Miracle-dz/UniFAR-FTUs huggingface dataset:
The Change of Laboratory Tests Could Be Predictive Factors for Infection after McKeown Esophagogastrectomy

Aim To analyze whether the change of laboratory tests (postoperative day 1 (POD1) minus pre-operation) could be predictive factors for postoperative infection in patients who have undergone McKeown esophagogastrectomy. Methods We retrospectively investigated the clinical data of 358 patients who have undergone McKeown esophagogastrectomy, and divided them into infection and noninfection groups. SPSS 22.0 software was performed for data analysis. Results In the two groups, smoking status (66.7% vs. 42.3%; P = 0.014), male gender (86.1% vs. 72.0%; P < 0.001), hoarseness (23.6% vs. 8.7%; P < 0.001), poor coughing ability (51.4% vs. 9.1%; P < 0.001), the change of WBC count (5.59 ± 4.75 × 109/L vs. 4.51 ± 4.11 × 109/L; P = 0.05), the change of glucose (6.03 ± 3.97 g/L vs. 3.78 ± 3.18 g/L), the change of ALB (−12.83 ± 3.45 g/L vs. −10.69 ± 3.86 g/L), the change of CRE (0.17 ± 19.94 umol/L vs. −4.02 ± 15.40 umol/L, P = 0.047) were significantly different. These factors were assessed using logistic regression analysis, and factors with P ≤ 0.05 in the univariate analysis were entered into multivariate analysis based on the forward stepwise (conditional) method. Poor coughing ability (odds ratio [OR], 11.034, 95% confidence interval [CI], 5.358–22.724), smoking status (OR, 4.218; 95% CI, 2.110–8.431), the change of WBC count (OR, 1.079; 95% CI, 1.000–1.164), the change of serum ALB level (OR, 0.849; 95% CI, 0.772–0.935), and the change of blood glucose levels (OR, 1.237; 95% CI, 1.117–1.371) were determined as independent risk factors for postoperative infection. We established a scoring system based on these 5 factors, and the area under the curve for this predictive model was 0.843 (range, 0.793–0.894); the sensitivity, specificity, and cut-off score were 70.8%, 85.3%, and 2.500, respectively. Conclusion Poor coughing ability, smoking habit, the high change of WBC and blood glucose levels, and low change of serum ALB levels can be used to predict the occurrence of postoperative infections among patients who have undergone McKeown esophagogastrectomy.
Clinical efficacy of Japanese herbal medicine daikenchuto in the management of fecal incontinence: A single-center, observational study

Objectives: The purpose of this study was to investigate whether the symptoms of fecal incontinence (FI) or anal sphincter dysfunction are improved by daikenchuto (DKT). Methods: This is a retrospective observational study that analyzes the effects of DKT. The study was conducted at Kunimoto Hospital. Patients who visited the hospital from January 2012 to December 2016 due to symptoms of FI with a certain degree of chronic constipation and who took DKT were enrolled. The drug to be evaluated was “Tsumura Daikenchuto Extract Granules for Ethical Use (TJ-100)” manufactured by Tsumura & Co., Tokyo, Japan. The primary outcome measures were changes in the scores of the Cleveland Clinic Incontinence Score (CCIS) and Constipation Scoring System (CSS) before and after the administration of DKT. Results: A total of 157 patients were enrolled. On the CCIS, “leakage of solid stool,” “leakage of liquid stool,” “pad use,” and “total score” were significantly improved. On the contrary, on the CSS, the score of “type of assistance” was significantly improved after the administration of DKT, but no significant difference was found in the total score. On the Bristol Stool Form Scale, the administration of DKT showed a tendency to normalize stool consistency. Maximum resting anal pressure and maximum squeeze anal pressure significantly increased after the administration of DKT. No side effects caused by DKT were observed during the study. Conclusions: DKT appears to be a safe and useful agent for the management of FI in patients with defecation disorders and internal anal sphincter dysfunction.
ATTITUDE AND WILLINGNESS OF INFERTILE PERSONS TOWARDS THE UPTAKE OF ASSISTED REPRODUCTIVE TECHNOLOGIES IN IBADAN, NIGERIA

Introduction: In most developing countries, the joy of every married man and woman is to procreate and raise children of their own. However, this desire does not always find fulfilment among some couples because of primary or secondary infertility. The majority who experience this condition live in developing countries where fertility services including Assisted Reproductive Technologies (ARTs) are not always available. This study, therefore, investigated the attitude and willingness of infertile persons to uptake ARTs. Methods: The study was a descriptive cross-sectional survey; a three-stage multi-stage sampling technique was adopted to select 202 married persons receiving fertility services at a gynaecological clinic in Ibadan, Nigeria. A validated interviewer-administered semi-structured questionnaire was used for data collection. Data were analysed using SPSS with descriptive and inferential statistics with the level of the significant set at ≤0.05. Results: Respondents' age was 34.3 years (SD ± 6.5); 88.6% were female; 55.5% had tertiary education; 54.5% reported a history of primary infertility. The negative attitude towards ARTs was observed among many of the respondents; however, some were willing to use ART services. In vitro fertilization (IVF) was the most preferred method; only 15.0% were optimistic of non-complications. The cost was the most mentioned barrier to use of ART. Positive association existed between attitude and willingness to use ART. Females are three times more likely than males to have a positive attitude toward the uptake of ART. Conclusion: Public enlightenment and advocacy are recommended to influence negative attitude towards ARTs.
Superior mesenteric venous thrombosis as a first manifestation of Antithrombin III deficiency in the postoperative course of laparoscopic sleeve gastrectomy: a case study of 2 patients from 1211 bariatric patients

Abstract Superior mesenteric venous thrombosis (SMVT) following laparoscopic sleeve gastrectomy (LSG) is a rare, potentially life-threatening complication, which presents either isolated, or as a part of portal/mesenteric/splenic vein thrombosis. Distinction between them possibly confers an important clinical and prognostic value. Antithrombin III (ATIII) deficiency causes an hypercoagulable state which predisposes to SMVT. We report the clinical presentation and treatment of two patients among 1211 LSGs (incidence = 0.165%) that presented with isolated SMVT and ATIII deficiency in an Academic Bariatric Center. Both patients had an unremarkable past medical history; none was smoker or had a previously known thrombophillic condition/thrombotic episode. Mean time of presentation was 15.5 days after LSG. Despite aggressive resuscitative and anticoagulation measures, surgical intervention was deemed necessary. No mortalities were encountered. Coagulation tests revealed ATIII deficiency in both patients.
Spontaneous Splenic Rupture Complicating Severe P. falciparum Infection: A Case Report and Literature Review

Spontaneous rupture of the spleen in malarial infection or malarial splenic rupture (MSR) is a rare but life-threatening condition complicating severe malarial infection in tropics and subtropics, and hence it deserves special attention. A high index of clinical suspicion is warranted for the early diagnosis as delayed or missed diagnosis can be potentially fatal. We report on a 32-year-old male who was diagnosed with severe Plasmodium falciparum infection and presented with an acute abdomen due to spontaneous splenic rupture. He was managed conservatively and had a successful outcome. The epidemiology, pathophysiology, clinical presentation, and management of MSR were briefly discussed in this report.
The Challenge of Treatment in Potential Celiac Disease

Potential celiac disease (PCD) is defined by the presence of positive serum antibodies, HLA-DQ2/DQ8 haplotypes, and a normal small intestinal mucosa (Marsh grade 0-1). This condition occurs in one-fifth of celiac disease (CD) patients and usually represents a clinical challenge. We reviewed genetic, histologic, and clinical features of this specific condition by performing a systematic search on MEDLINE, Embase, and Scholar database. Accordingly, we identified different genetic features in patients with PCD compared to the classical forms. Frequently, signs of inflammation (deposits of immunoglobulin A (IgA) and/or increased number of intraepithelial lymphocytes) can be clearly identify in the mucosa of PCD patients after an accurate histological assessment. Finally, the main challenge is represented by the treatment: the gluten-free diet should be considered only in the presence of gluten-dependent symptoms in both children and adults. What is known: (i) potential celiac disease (PCD) occurs in one-fifth of all celiac diseases (CD), and (ii) despite the absence of classical lesions, clear signs of inflammation are often detectable. What is new: (i) patients with PCD show different genetic features, and (ii) the presence of gluten-dependent symptoms is the main determinant to initiate the gluten-free diet, after a complete diagnostic work-up.
Successful Integration of Face-to-Face Bootcamp Lab Courses in a Hybrid Online STEM Program†

The Microbiology and Cell Science program at the University of Florida compressed two standard 16-week lab courses into five-day versions of the course, which are referred to as bootcamp labs. The bootcamp labs have the same objectives, activities, and assessments as their traditional counterparts. Development of the bootcamp labs was part of a larger effort to increase access to the major, and more broadly STEM, by offering a 2+2 hybrid online transfer program. The results of this mixed-methods study include a direct comparison between bootcamp and traditional lab format as an approach for delivery of a face-to-face lab course. The bootcamp lab cohort has a greater diversity of students, with more women and underrepresented minorities in STEM than the traditional semester-long cohorts. Students in the bootcamp labs have comparable grade outcomes and learning gains to students in traditional lab format. Regression analysis identified GPA, but not lab format, as the most significant predictor of success for students enrolled in lab courses. Qualitative results suggest that the bootcamp format may be a better way than traditional formats to teach microbiology lab. In summary, the results demonstrate that a bootcamp version of a face-to-face microbiology course is just as effective as the traditional semester-long version. This work has broader implications as it supports the bootcamp lab approach as a model in STEM education for increasing access and for overcoming a major barrier to online STEM programs: face-to-face delivery of key lab courses.
Are Changes in Distance-Run Performance of Australian Children between 1985 and 1997 Explained by Changes in Fatness?

The aim of this study was to determine whether changes in fitness performance could be explained by changes in body fatness. Two hundred seventy-nine 10- to 12-year-old children were tested in 1985 as part of a national survey. They were matched for age, sex, body-mass index, and triceps skin-fold thickness with 279 children from a 1997 survey. Average speeds on the 1.6 km walk/run test were compared. Children from the 1997 survey performed significantly worse than their matched peers from the 1985 survey. The decline in performance was evident for boys, girls, and all children. Matching for fatness reduced performance differences by about 61% in boys, and 37% in girls. Declines in fitness performance in this population have not been entirely due to increases in fatness.
Knockdown of SET Domain, Bifurcated 1 suppresses head and neck cancer cell viability and wound-healing ability in vitro

Head and neck cancer (HNC) is the sixth most common cancer worldwide and therefore presents a global public health problem. There are no standard algorithms for the diagnosis and follow-up of the disease, and no effective current treatment approaches exist. Therefore, the discovery of new biomolecules and the design of new strategies to aid in early diagnosis is necessary, along with establishing prognostic factors of HNC. In several cancer studies, the upregulation of SET Domain, Bifurcated 1 (SETDB1) has been reported to be tumor-inducing and to indicate a cancer-invasive prognosis, leading to the modulation of genes associated with different signaling pathways; however, the literature is sparse regarding the relationship between SETDB1 and HNC. In our study, three HNC primary cell lines and their corresponding metastatic cell lines were used. The quantitative reverse transcriptase-polymerase chain reaction and western blotting data indicated that the SETDB1 mRNA and protein expression levels were higher in all metastatic cell lines compared to their primary cell lines (P < 0.05 for all). To investigate the role of SETDB1 in HNC biology, in vitro functional analyses were carried out using small interference RNA (siRNA) technology, cell viability, scratch wound-healing, and the caspase-3 activity assay of gene expression of SETDB1 to compare primary and metastatic cell lines of HNC. Metastatic cells were more susceptible to this suppression, which decreased the vitality of cells and their ability of wound-healing and induced level of caspase-3 activity (P < 0.05 for all). This functional study has shown that SETDB1 plays an important role in head and neck carcinogenesis. Therefore, SETDB1 may be an attractive therapeutic target molecule and also a potential diagnostic and prognostic biomarker in HNC.
Inotropes in Acute Heart Failure: From Guidelines to Practical Use: Therapeutic Options and Clinical Practice

Inotropes are pharmacological agents that are indicated for the treatment of patients presenting with acute heart failure (AHF) with concomitant hypoperfusion due to decreased cardiac output. They are usually administered for a short period during the initial management of AHF until haemodynamic stabilisation and restoration of peripheral perfusion occur. They can be used for longer periods to support patients as a bridge to a more definite treatment, such as transplant of left ventricular assist devices, or as part of a palliative care regimen. The currently available inotropic agents in clinical practice fall into three main categories: beta-agonists, phosphodiesterase III inhibitors and calcium sensitisers. However, due to the well-documented potential for adverse events and their association with increased long-term mortality, physicians should be aware of the indications and dosing strategies suitable for different types of patients. Novel inotropes that use alternative intracellular pathways are under investigation, in an effort to minimise the drawbacks that conventional inotropes exhibit.
Epidemiology of Alzheimer's Disease and Dementia in Arab Countries: A Systematic Review

Background/Objectives Contrary to popular belief, the condition of dementia is not an actual discrete disease, but rather a group of symptoms, most notable of which is the disturbance of memory and social ability, often severe enough to impair daily functioning. As a result, it has been a major cause of functional deterioration among varying populations in the world. This study is aimed at reviewing the epidemiology of dementia in Arab countries in terms of its prevalence, distribution, and risk factors. Methods A systematic literature review was conducted using articles published in PubMed, Embase, Scopus, and other local journals between 1990 and 2018. After applying the inclusion and exclusion criteria, a total of 18 studies were concluded to be eligible for the review. Results Prevalence studies demonstrated that dementia is indeed a prevalent condition in Arab countries, ranging between 1.1% and 2.3% among age groups of 50 years and older, as well as between 13.5% and 18.5% among age groups of 80 years and above. However, these results are not different from those of many other countries in the world. Moreover, prevalence was found to vary depending on sociodemographic characteristics. Major risk factors of dementia included hypertension, low income, and low education, while the risk of developing dementia is increased by obesity, diabetes mellitus, and cardiovascular risk factors. Despite the growing evidence regarding the epidemiological distribution and determinants of dementia worldwide, studies from the Arab region remain scarce. Conclusion This systematic review highlights the need for population-based studies to provide necessary information for developing preventive and curative strategies specific to the Arab region.
Managerial reporting by food production companies in Slovakia in 2017

Abstract Corporate reporting on non-financial information has been currently gaining much more interest compared to the past. Most food enterprises believe that performing responsibly and showing an interest in society and the environment will produce a profit and benefit them as well as society. Such cases, in which enterprises report on non-financial information, were the subject of this research. The study aims to discover the managerial reporting of 2017 on the social and environmental effects of food companies in Slovakia to better understand problems in this regard. 2017 was the first year when enterprises were required to draft annual reports containing non-financial information following the amendment to the Slovak law that resulted from the European Union requirements. Across the world, reporting on non-financial information is regulated by voluntary guidelines. The paper presents conclusions of a content analysis of annual food business reports in the Slovak Republic in the context of G4 (GRI) directives from social and environmental points of view as key elements in social responsibility reporting. Individual social and environmental aspects of the research are disclosed by an enterprise if the information in its annual report conforms to defined G4 activities (GRI). All the food enterprises operating in Slovakia that compiled annual reports for 2017 were included in the research. Therefore, 142 annual reports with economic activities in 26 subclasses in the food industry sector were selected. The results present a current and comprehensive (full) reporting overview of this industry in Slovakia and reveal several shortcomings in executive reporting. The analysis of the environmental information in the annual reports shows that food enterprises reporting on environmental protection mainly focus on waste, product services, wastewater, materials and energy, evidenced by information about ongoing monitoring of the environmental impacts of production. In the social category, the G4 (GRI) directive defines four main aspects: (i) labour relations and the environment, (ii) human rights, (iii) society and (iv) liability for products.
Effect of parameter selection on different topological structures for Particle Swarm Optimization algorithm

Abstract Particle Swarm Optimization is an evolutionary optimization algorithm, largely studied during the years: analysis of convergence, determination of the optimal coefficients, hybridization of the original algorithm and also the determination of the best relationship structure between the swarm elements (topology) have been investigated largely. Unfortunately, all these studies have been produced separately, and the same coefficients, derived for the original topology of the algorithm, have been always applied. The intent of this paper is to identify the best set of coefficients for different topological structures. A large suite of objective functions are considered and the best compromise coefficients are identified for each topology. Results are finally compared on the base of a practical ship design application.
Weed control efficacy of hoe weeding and commercially formulated mixture of metolachlor + prometryn herbicide under maize production in soil amended with biochar

Abstract Successful cultivation of maize depends largely on efficient weed control, adequate supply of essential nutrients and sufficient soil moisture. Screenhouse and field trials were conducted at the Teaching and Research Farm of the Federal University of Agriculture, Abeokuta, Nigeria during the early and late cropping season of 2013 to evaluate effects of biochar integrated with manual weeding and pre-emergence herbicides on weed control efficiency and productivity of maize. The screenhouse trial was a 6 × 5 factorial experiment fitted into Completely Randomized Design in three replicates. The two factors were biochar: 0, 2, 4, 6, 8 and 10 t ha−1 and weed control methods: weedy check, hoe weeding at 6 Weeks After Sowing (WAS), hoe weeding at 3, 6, and 9 WAS, pre-emergence herbicide application (Codal Gold) at 1.0 and 2.0 kg a.i./ha−1. The field trial was laid out in split-plot arrangement fitted into Randomized Complete Block Design with three replicates. The three main treatments plots on the field consisted of the optimum rates of biochar obtained in the screenhouse (10 t ha−1) compared with 20 t ha−1 and 0 t ha−1 which served as the control. The sub-plots treatments consisted of weed control methods used in the screen house experiment. Data were collected on grain yield and weed dry matter. The result showed that biochar at 10 and 20 t ha−1 in the screenhouse and field trials, respectively, resulted in significantly (P < 0.05) higher grain yield compared with other rates tested. Highest grain yield was obtained in pots hoe weeded thrice at 3, 6 and 9 WAS. Whereas similar grain yield was recorded in plot weeded once at 6 WAS and that hoe weeded at 3, 6 and 9 WAS in the field experiment. Biochar application of 20 t ha−1 gave optimum maize yield. Among the weed control treatments manual weeding either at 6 WAS or at 3, 6 and 9 WAS recorded the highest grain yields. Therefore, incorporation of biochar with either preemergence herbicide or manual hoe weeding would enhance the growth and yield of maize.
Current possibilities of mechanized logging in mountain areas

Abstract Modern technologies allow wood harvest in almost all terrains, including hard-to-reach mountain areas. Each of the technical measures used, however, has limitations due to its construction and the nature of the work. The present study discusses issues related to the selection of machinery and technology as well as planning work in mountainous terrain, taking into account factors such as accessibility of the stand and terrain properties (slope, ground bearing capacity). Adaptive changes of forest machinery for work in mountain stands are also presented. This article furthermore discusses possibilities of applying machinery and technologies already used in other countries to harvest wood in mountainous forests in Poland.
Structure, composition and diversity of trees within the dry evergreen reserve forest of Kondapalli (Eastern Ghats, southern India)

Abstract The dry evergreen forest of Kondapalli (Andhra Pradesh state, India) is declared as a forest reserve, but, despite of this, it is subjected to degradation resulting in loss of biodiversity. Thus, the current study was carried out to investigate the tree diversity of Kondapalli forest. A total of 566 ±16 trees (≥10 cm) representing 46±8 species from 40 genera and 21 families were recorded from the 0.36 ha area of Kondapalli forest. Mimosaceae was the most species rich family, while Rutaceae was the most abundant family. Atalantia monophylla was most frequent and abundant species and, with respect to basal area, Melia azedarach and Syzygium cumini were the dominant taxa. The recorded stem density was 1572 stems ha−1 and the mean forest basal area was 47.17 m2 ha−1. The results of cluster analysis revealed that Atalantia monophylla, characterised by a high ecological amplitude, had a wide distribution and was associated with species forming different communities. The study showed that Kondapalli forest is characterised by a fairly high species richness, which provides the baseline data on the floristic structure and diversity of this forest for better management and conservation.