Miracle-dz/UniFAR-FTUs huggingface dataset:
In situ and Operando Raman Spectroscopy of Layered Transition Metal Oxides for Li-ion Battery Cathodes

In situ and operando Raman spectroscopy is proposed to provide unique means for deeper fundamental understanding and further development of layered transition metal LiMO2 (M=Ni,Co,Mn) oxides suitable for Li-ion battery applications. We compare several spectro-electrochemical cell designs and suggest key experimental parameters for obtaining optimum electrochemical performance and spectral quality. Studies of the most practically relevant LiMO2 compositions are exemplified with particular focus on two experimental approaches: (1) lateral and axial Raman mapping of the electrode’s (near-) surface to monitor inhomogeneous electrode reactions and (2) time-dependent single-particle spectra during cycling to analyze the LixMO2 lattice dynamics as a function of lithium content. Raman Spectroscopy is claimed to provide a unique real-time probe of the M-O bonds, which are at the heart of the electrochemistry of LiMO2 oxides and govern their stability. We highlight the need for further fundamental understanding of the relationships between the spectroscopic response and oxide lattice structure with particular emphasis on the development of a theoretical framework linking the position and intensity of the Raman bands to the local LixMO2 lattice configuration. The use of complementary experimental techniques and model systems for validation also deserve further attention. Several novel LiMO2 compositions are currently being explored, especially containing dopings and coatings, and Raman Spectroscopy could offer a highly dynamic and convenient tool to guide the formulation of high specific charge and long cycle life LiMO2 oxides for next-generation Li-ion battery cathodes.
Awake Rat Brain Functional Magnetic Resonance Imaging Using Standard Radio Frequency Coils and a 3D Printed Restraint Kit

Functional magnetic resonance imaging (fMRI) is a powerful noninvasive tool for studying spontaneous resting state functional connectivity (RSFC) in laboratory animals. Brain function can be significantly affected by generally used anesthetics, however, rendering the need for awake imaging. Only a few different awake animal habituation protocols have been presented, and there is a critical need for practical and improved low-stress techniques. Here we demonstrate a novel restraint approach for awake rat RSFC studies. Our custom-made 3D printed restraint kit is compatible with a standard Bruker Biospin MRI rat bed, rat brain receiver coil, and volume transmitter coil. We also implemented a progressive habituation protocol aiming to minimize the stress experienced by the rats, and compared RSFC between awake, lightly sedated, and isoflurane-anesthetized rats. Our results demonstrated that the 3D printed restraint kit was suitable for RSFC studies of awake rats. During the short 4-day habituation period, the plasma corticosterone concentration, movement, and heart rate, which were measured as stress indicators, decreased significantly, indicating adaptation to the restraint protocol. Additionally, 10 days after the awake MRI session, rats exhibited no signs of depression or anxiety based on open-field and sucrose preference behavioral tests. The RSFC data revealed significant changes in the thalamo-cortical and cortico-cortical networks between the awake, lightly sedated, and anesthetized groups, emphasizing the need for awake imaging. The present work demonstrates the feasibility of our custom-made 3D printed restraint kit. Using this kit, we found that isoflurane markedly affected brain connectivity compared with that in awake rats, and that the effect was less pronounced, but still significant, when light isoflurane sedation was used instead.
Workplace Bullying and Psychological Distress: A Longitudinal Multilevel Analysis Among Japanese Employees

Objective: We sought to investigate the contextual effect of workplace bullying on subsequent individual psychological distress and intention to leave. Methods: A longitudinal study was conducted among 3142 Japanese employees in the public sector. Both the baseline and follow-up questionnaires inquired about demographic and occupational characteristics, workplace bullying, psychological distress, and intention to leave. Results: The results of three-level (individual—division—department) multilevel analyses revealed that division-level workplace bullying was associated with increased individual-level psychological distress after adjustment for individual experience of workplace bullying, while the association between individual experience of bullying and psychological distress was not statistically significant in the same model. Conclusion: The results of the current study suggest that the presence of bullying in the workplace can have a detrimental effect on employees’ mental health even if they are not personally victimized.
Why does work cause fatigue? A real-time investigation of fatigue, and determinants of fatigue in nurses working 12-hour shifts.

BACKGROUND One of the striking regularities of human behavior is that a prolonged physical, cognitive, or emotional activity leads to feelings of fatigue. Fatigue could be due to (1) depletion of a finite resource of physical and/or psychological energy or (2) changes in motivation, attention, and goal-directed effort (e.g. motivational control theory). PURPOSE To contrast predictions from these two views in a real-time study of subjective fatigue in nurses while working. METHODS One hundred nurses provided 1,453 assessments over two 12-hr shifts. Nurses rated fatigue, demand, control, and reward every 90 min. Physical energy expenditure was measured objectively using Actiheart. Hypotheses were tested using multilevel models to predict fatigue from (a) the accumulated values of physical energy expended, demand, control, and reward over the shift and (b) from distributed lag models of the same variables over the previous 90 min. RESULTS Virtually all participants showed increasing fatigue over the work period. This increase was slightly greater when working overnight. Fatigue was not dependent on physical energy expended nor perceived work demands. However, it was related to perceived control over work and perceived reward associated with work. CONCLUSIONS Findings provide little support for a resource depletion model; however, the finding that control and reward both predicted fatigue is consistent with a motivational account of fatigue.
Augmenting Statistical Machine Translation with Subword Translation of Out-of-Vocabulary Words

Most statistical machine translation systems cannot translate words that are unseen in the training data. However, humans can translate many classes of out-of-vocabulary (OOV) words (e.g., novel morphological variants, misspellings, and compounds) without context by using orthographic clues. Following this observation, we describe and evaluate several general methods for OOV translation that use only subword information. We pose the OOV translation problem as a standalone task and intrinsically evaluate our approaches on fourteen typologically diverse languages across varying resource levels. Adding OOV translators to a statistical machine translation system yields consistent BLEU gains (0.5 points on average, and up to 2.0) for all fourteen languages, especially in low-resource scenarios.
Learning alternatives:a last chance or a real choice?

But it is not just a metaphor it is the most powerful driver of change in the way we live, consume and learn. It is the most persuasive thing that convinces us of our individual autonomy and it is the most powerful influence in shaping our identity. This is because our individual personality is increasingly tied to the degree of control we can exercise, or at least what we perceive we can exercise, over what we do. In this sense the temptation is to identify 'what we choose' as synonymous with 'who we are'.
Internal doses from radionuclides and their health effects following the Fukushima accident

This paper presents an overview of current internal dose estimates from the Fukushima accident, potential population specific uncertainties in these estimates are investigated, along with the relative effects of internal and external exposures. Thyroid doses were largely due to 131I, but variations in thyroid weight and fractional uptake and retention times of 131I in the thyroid contribute to uncertainties in thyroid dose estimates. Lower values for these parameters in the Japanese population, as compared to international reference assumptions, would lead to underestimation of doses on the basis of reference thyroid weights and overestimation of doses using reference thyroid uptake and retention times. Any overall bias in thyroidal doses due to population specific factors is the net result of the balance between these effects. Internal doses to other organs are largely due to 134Cs and 137Cs and their whole body distribution, population specific differences in these dose estimates are driven by average body mass, due to the inverse relationship between this and retention times. Potential differences in dose estimates and any inferred risks, due to local population specific factors, may be less than a factor of two for children and male adults, but the potential difference may be slightly underestimated for female adults. Recent micro-dosimetric studies have confirmed the existing perception that risk from internal exposures to 137Cs, 134Cs, and 131I should be nearly equivalent to that from external exposure to gamma rays at the same absorbed dose. Epidemiological studies provide comparisons between external and internal exposures to 131I in children and suggest that effects of internal exposure are similar to those of external exposure. Effective dose has been formulated to harmonise internal and external exposure risks for radiation protection purposes. On the basis of this review, the use of effective dose in this context does not seem to be unreasonable.
Prospective Evaluation of Utilization Patterns and Prescribing Guidelines of Opioid Consumption Following Orthopedic Foot and Ankle Surgery

Background: Overprescription of narcotic pain medication is a major culprit in the present opioid epidemic plaguing the United States. The current literature on lower extremity opioid usage has limitations and would benefit from additional study. The purpose of our study was to prospectively assess opioid consumption patterns following outpatient orthopedic foot and ankle procedures. Methods: Patients undergoing outpatient orthopedic foot and ankle procedures who met inclusion criteria had the following prospective information collected: patient demographics, preoperative health history, patient-reported outcomes, anesthesia type, procedure type, opioid prescription and consumption details. The morphine equivalent dose was calculated for each prescription and then converted to the equivalent of a 5-mg oxycodone “pill. ” Univariable analyses were performed to identify variables with a statistically robust association with opioid consumption for inclusion in a multivariable linear regression. A stepwise backward regression was then performed to identify independent predictors of opioid consumption. Postoperative opioid utilization was reported for 988 patients (mean age: 49 years). Results: Overall, patients consumed a median of 20 pills whereas the median number of pills prescribed was 40. This resulted in a utilization rate of 50% and 20 631 pills left unused. Independent factors associated with higher opioid consumption were anesthesia type (P < .004), age <60 years (P < .001), preoperative visual analog scale (VAS) pain report of >6 (P = .008), and bony procedures (P = .008); residual standard error 16.73 (F7,844=14.3, P < .001). Conclusion: Our study found that patients who underwent orthopedic foot and ankle procedures were overprescribed narcotic medication by nearly twice the amount that was actually consumed. Although we identified 4 independent factors associated with opioid consumption, the large residual standard error suggests that there remains a substantial degree of unexplained variance of opioid consumption observed in the patient population. Physicians face a challenging task of setting appropriate protocols when balancing pain relief and generalizable guidelines. Level of Evidence: Level II, prospective observational cohort study.
An Analysis of Informed Consent Form Readability of Oncology Research Protocols

Twenty-two percent of adults in the United States have only basic health literacy skills. We used a multiple linear regression model to identify associations between readability of informed consent documents with study sponsor, study phase, and approval year using a sample of 143 oncology studies at Ochsner Medical Center. The M ± SD Flesh-Kincaid Reading Grade Level (RGL) was 10.33 ± 0.85 and Flesh Reading Ease (FRE) was 52.89 ± 5.49. National Cancer Institute studies had a significantly lower mean RGL and FRE as compared with other sponsors (RGL 9.85 ± 0.66 vs. 10.72 ± 0.79; p value < .0001). Mean RGL did not differ by study phase. Future research should include assessment and improvement of the readability of informed consent documents.
Stigma, Coping, and Alcohol Use Severity Among People Living With HIV: A Prospective Analysis of Bidirectional and Mediated Associations.

Background HIV-related stigma is associated with health consequences among people living with HIV, including increased risk for alcohol problems. Theory suggests that maladaptive coping may mediate the relationship between HIV-related stigma and alcohol outcomes, and these variables may be bidirectionally associated over time. However, no studies have examined the temporal relationships among these variables in people living with HIV. Purpose This study examined prospective bidirectional and mediated associations among HIV-related stigma, maladaptive coping, and alcohol use severity in patients enrolled in the Ontario HIV Treatment Network Cohort study. Method Patients receiving care for HIV (N = 1,520) at one of several clinics completed self-report measures annually. Data were analyzed in a four-wave, cross-lagged panel model. Results Greater HIV-related stigma at each wave consistently predicted increased maladaptive coping 1 year later. Similarly, maladaptive coping consistently predicted greater subsequent HIV-related stigma. Further, we observed some evidence that maladaptive coping mediated the prospective associations between HIV-related stigma and alcohol use severity in both directions (i.e., stigma to subsequent alcohol use severity and vice versa) although these associations were not observed across all waves. Conclusion Results suggest that HIV-related stigma and maladaptive coping are bidirectionally associated with one another over time. This study also provides some evidence that coping may be a relevant mediator of these associations, although findings were less consistent for mediated pathways. Future research should examine whether interventions addressing stigma and coping among people living with HIV may help to minimize health risks such as hazardous drinking.
Confidence and RISC: How Russian papers indexed in the national citation database Russian Index of Science Citation (RISC) characterize universities and research institutes

The paper analyses Russian Index of Science Citation (RISC), a national citation database. We continue our previous study (Moskaleva et al., 2018) and focus on difference between bibliometric indicators calculated on, so to say, "the best" journals, so called RISC Core, and those which take into account all Russian journals available. Such a difference may show focuses of insitutional actors on different document types, publication strategies etc.
Recognising the importance of informal communication events in improving collaborative care

Background While the concept of collaboration is highly touted in the literature, most descriptions of effective collaboration highlight formal collaborative events; largely ignored are the informal collaborative events and none focusing on the frequent, ‘seemingly’ by chance communication events that arise and their role in supporting patient safety and quality care. Objective To identify the types of informal communication events that exist in the inpatient setting and better understand the barriers contributing to their necessity. Methods We undertook a constructivist grounded theory study in an inpatient internal medicine teaching unit in Ontario, Canada. Interview and observational data were collected across two phases; in total, 56 participants were consented for the study. Data collection and analysis occurred iteratively; themes were identified using constant comparison methods. Results Several types of informal communication events were identified and appeared valuable in three ways: (1) providing a better sense of a patient’s baseline function in comparison to their current function; (2) gaining a more holistic understanding of the patient’s needs; and (3) generating better insight into a patient’s wishes and goals of care. Participants identified a number of organisational and communication challenges leading to the need for informal communication events. These included: scheduling, competing demands and the spatial and temporal organisation of the ward. As a result, nursing staff, allied health professionals and caregivers had to develop strategies for interacting with the physician team. Conclusion We highlight the importance of informal communication in supporting patient care and the gaps in the system contributing to their necessity. Changes at the system level are needed to ensure we are not leaving important collaborative opportunities to chance alone.
What Fantasies Can Do to Your Relationship: The Effects of Sexual Fantasies on Couple Interactions

Research addressing the underlying functions of sexual fantasies has mainly focused on variables associated with frequency and content of fantasies. Relatively less is known about how sexual fantasizing affects the relationship. Four studies examined the contribution of fantasizing about one’s partner (“dyadic fantasies”) to relationship outcomes. In Studies 1 and 2, participants fantasized either about their partner or about someone else and rated their desire to engage in sex and other nonsexual relationship-promoting activities with their partner. In Studies 3 and 4, romantic partners recorded their fantasies and relationship interactions each evening for a period of 21 and 42 days, respectively. In Study 4, partners also provided daily reports on relationship perceptions. Overall, dyadic fantasizing was associated with heightened desire and increased engagement in relationship-promoting behaviors. Relationship perceptions explained the link between dyadic fantasies and relationship-promoting behaviors, suggesting that such fantasies benefit the relationship by enhancing partner and relationship appeal.
Association between socio-economic status and physical activity is mediated by social support in Brazilian students

ABSTRACT This study evaluated whether the relationship between socioeconomic status (SES) and moderate-to-vigorous physical activity (MVPA) is mediated by social support of peers and parents. A cross-sectional study included students (n = 1182) aged 11 to 18 years who were recruited in 2014 from public schools in Fortaleza, Brazil. Participants completed a questionnaire to assess all variables. Mediation analyses were performed to determine the role of parental support and peer support on the relationship between SES and MVPA. Also, moderated-mediation analyses with estimating of conditional indirect effects were performed in order to identify whether gender is a moderator of the mediating effect. A positive and significant association between SES and MVPA was found among Brazilian students, and social support of parents and peers were significant mediators of this relationship. Conditional indirect effects showed that both parental and peer support had a significant indirect effect among boys; only parental support had a significant indirect effect among girls. These results suggest that improving social support can help reduce the impact of SES on physical activity among Brazilian adolescents.
Uptake of NHS health check: issues in monitoring

Abstract Within the NHS health check (NHSHC) programme, there is evidence of marked inconsistencies and challenges in practice-level self-reporting of uptake. Consequently, we explored the perceptions of those involved in commissioning of NHSHC to better understand the implications for local and national monitoring and evaluation of programme uptake. Semi-structured, one-to-one, telephone interviews (n=15) were conducted with NHSHC commissioners and leads, and were analysed using inductive thematic analysis. NHSHC data were often collected from practices using online extraction systems but many still relied on self-reported data. Performance targets and indicators used to monitor and feedback to general practices varied between localities. Participants reported a number of issues when collecting and reporting data for NHSHC, namely because of opportunistic checks. Owing to the perceived inaccuracies in reporting, there was concern about the credibility and relevance of national uptake figures. The general practice extraction service will be important to fully understand uptake of NHSHC.
The Arabidopsis LDL1/2-HDA6 histone modification complex is functionally associated with CCA1/LHY in regulation of circadian clock genes

Abstract In Arabidopsis, the circadian clock central oscillator genes are important cellular components to generate and maintain circadian rhythms. There is a negative feedback loop between the morning expressed CCA1 (CIRCADIAN CLOCK ASSOCIATED 1)/LHY (LATE ELONGATED HYPOCOTYL) and evening expressed TOC1 (TIMING OF CAB EXPRESSION 1). CCA1 and LHY negatively regulate the expression of TOC1, while TOC1 also binds to the promoters of CCA1 and LHY to repress their expression. Recent studies indicate that histone modifications play an important role in the regulation of the central oscillators. However, the regulatory relationship between histone modifications and the circadian clock genes remains largely unclear. In this study, we found that the Lysine-Specific Demethylase 1 (LSD1)-like histone demethylases, LDL1 and LDL2, can interact with CCA1/LHY to repress the expression of TOC1. ChIP-Seq analysis indicated that LDL1 targets a subset of genes involved in the circadian rhythm regulated by CCA1. Furthermore, LDL1 and LDL2 interact with the histone deacetylase HDA6 and co-regulate TOC1 by histone demetylation and deacetylaion. These results provide new insight into the molecular mechanism of how the circadian clock central oscillator genes are regulated through histone modifications.
Ageing stereotypes influence the transmission of false memories in the social contagion paradigm

ABSTRACT These experiments are the first to investigate the impact of confederate accuracy, age, and age stereotypes in the social contagion of memory paradigm. Across two experiments, younger participants recalled household scenes with an actual (Experiment 1) or virtual (Experiment 2), older or younger confederate who suggested different proportions (0%, 33% or 100%) of false items during collaboration. In Experiment 2, positive and negative age stereotypes were primed by providing bogus background information about our older confederate before collaboration. Across both experiments, if confederates suggested false items participants readily incorporated these into their own memory reports. In Experiment 1, when no age stereotype was primed, participants adopted similar proportions of false items from younger and older confederates. Importantly, in Experiment 2, when our older confederate was presented in terms of negative ageing stereotypes, participants reported less false items and were better able to correctly identify the source of those false items.