Miracle-dz/UniFAR-FTUs huggingface dataset:
Proteome analysis of wheat embryo (Triticum aestivum) Sensu stricto germination under osmotic stress.

Seed germination is an important growth phase in the plant life cycle that can be injured by osmotic stress. Germination is divided into three phases and many processes are initiated before radical protrusion. Many metabolic activities occur, especially in Sensu stricto germination phase since the seed embryo is a live organ, so differences in protein patterns are important in this phase. This study was carried out to find out the effects of osmotic stress on protein patterns in Sensu stricto germination phase. Effects of osmotic stress (-12 bar) on T. aestivum embryo (Sardari and Qods, tolerant and susceptible cultivars, respectively) proteins were evaluated. An osmotic potential of -12 bar was selected as the critical stress level, because at this treatment, germination percentage in susceptible cultivar was too low, but in tolerant cultivar was 50% as compared to control condition. Osmotic stress decreased germination percentage and caused adverse effects on protein patterns. After 2-DE proteome analysis of wheat embryo axis, 1000 spots were reproducible, although 16 spots were expressed differentially. Five protein categories were identified by MALDITOF/TOF in 16 differentially expressed, including energy (19%), stress/disease /defense (25%), metabolism (37%), protein synthesis/degradation (13%), and signal transduction (6%). Therefore, it should be noted that seeds were acting as intelligent systems which has an important role in response mechanism to osmotic stress during germination, especially before radical protrusion. In this study, it was demonstrated that stress and metabolism-related proteins such as HSPs, 1–Cys peroxiredoxin, alpha amylase inhibitor, and ADP–glucose pyrophosphorylase were more than other protein classes had vital roles in response to osmotic stress at 24 HAI. The results indicated that protein abundance under osmotic stress depends on the severity and amount of stress and imbibition time.
The measure matters: Language dominance profiles across measures in Spanish–English bilingual children*

The purpose of this study was to determine if different language measures resulted in the same classifications of language dominance and proficiency for a group of bilingual pre-kindergarteners and kindergarteners. Data were analyzed for 1029 Spanish–English bilingual pre-kindergarteners who spanned the full range of bilingual language proficiency. Parent questionnaires were used to quantify age of first exposure and current language use. Scores from a short test of semantic and morphosyntactic development in Spanish and English were used to quantify children's performance. Some children who were in the functionally monolingual range based on interview data demonstrated minimal knowledge of their other languages when tested. Current use accounted for more of the variance in language dominance than did age of first exposure. Results indicate that at different levels of language exposure children differed in their performance on semantic and morphosyntax tasks. These patterns suggest that it may be difficult to compare the results of studies that employ different measures of language dominance and proficiency. Current use is likely to be a useful metric of bilingual development that can be used to build a comprehensive picture of child bilingualism.
Efficient ConvNet Feature Extraction with Multiple RoI Pooling for Landmark-Based Visual Localization of Autonomous Vehicles

Efficient and robust visual localization is important for autonomous vehicles. By achieving impressive localization accuracy under conditions of significant changes, ConvNet landmark-based approach has attracted the attention of people in several research communities including autonomous vehicles. Such an approach relies heavily on the outstanding discrimination power of ConvNet features to match detected landmarks between images. However, a major challenge of this approach is how to extract discriminative ConvNet features efficiently. To address this challenging, inspired by the high efficiency of the region of interest (RoI) pooling layer, we propose a Multiple RoI (MRoI) pooling technique, an enhancement of RoI, and a simple yet efficient ConvNet feature extraction method. Our idea is to leverage MRoI pooling to exploit multilevel and multiresolution information from multiple convolutional layers and then fuse them to improve the discrimination capacity of the final ConvNet features. The main advantages of our method are (a) high computational efficiency for real-time applications; (b) GPU memory efficiency for mobile applications; and (c) use of pretrained model without fine-tuning or retraining for easy implementation. Experimental results on four datasets have demonstrated not only the above advantages but also the high discriminating power of the extracted ConvNet features with state-of-the-art localization accuracy.
Construction of Efficient q-ary Balanced Codes

Knuth proposed a simple scheme for balancing codewords, which was later extended for generating q-ary balanced codewords. The redundancy of existing schemes for balancing q-ary sequences is larger than that of the full balanced set which is the minimum achievable redundancy. In this article, we present a simple and efficient method to encode the prefix that results in less redundancy for the construction of q-ary balanced codewords.
Early warning signs of failure in offshore outsourced software project – an indo-german case study

Due to the cultural and linguistic differences, different time zones, and complexities of knowledge transfer involved in IT offshoring, offshore-outsourced projects are more prone to failure than in-house and domestically outsourced projects. These inherent risks exacerbate the communication, coordination and collaboration between vendors and clients and thus affect various stages of the offshore outsourced software development (OOSD). Several academic and practitioner studies have reported about the failed offshore projects. Although there is no silver bullet to overcome the inherent risks , the postmortem examination of failed projects has shown that long before the failure there were significant symptoms or early warning signs (EWS) of trouble. An EWS can be defined as an event or indication that predicts or cautions one of possible or impending problems in the first 20 % of the project‟s cooperation or collaboration period between clients and vendors. These signs become more significant in the unique onshore-offshore environment, where the risks are higher and there is a need for an early warning mechanism that helps to avoid failures. We analyze a failed project case that involved an Indo-German OOSD contractual arrangement for a web development project in this work. Based on explorative, in-depth case study, we identify the EWSs of failure and develop a preliminary model to understand the failures. Although this study is based on just one case study, it provided exclusive insights from both vendor and client perspectives to study the EWSs from a team perspective and to understand the interrelations between the EWS categories.
Oncogene activation by chromosome translocation in human malignancy.

INTRODUCTION 322 BURKITT'S LYMPHOMA-A PARADIGM FOR LYMPHOID MALIGNANCy. 323 Chromosomal Aberrations in Burkitt's Lymphomas. 323 Molecular Analysis of Burkitt's Lymphoma Translocations . 325 THE NORMAL FUNCTION AND REGULATION OF c·myc 326 The Structure and Function of c-myc . 326 The Regulation of c-myc . 327 TRANSLOCATION-ASSOCIATED DEREGULATION OF c-myc IN BURKITT'S LyMPHOMAS . 327 Transcriptional Deregulation of c-myc . 328 ACTIVATION OF OTHER ONCOGENES BY THE IgH LOCUS: bcl-J and bc1-2. 329 Molecular Analysis of the t(lJ ;14) Translocation . 330 Molecular Analysis of the ((14;18) Translocation . 330 ACTIVATION OF TRANSLOCATED ONCOGENES BY THE T-CELL RECEPTOR LOCI . 331 Molecular Analyses of T-Cell Translocations . 331 THE MECHANISM OF TRANSLOCATION IN LYMPHOID MALIGNANCIES. 333 B-Cell Translocation Mechanisms . 333 T-Cell Translocation Mechanisms . 334 LYMPHOID MALIGNANCY: A SUMMARy. 335 THE MOLECULAR BIOLOGY OF THE PHILADELPHIA CHROMOSOME. 335 The Proto-Oncogene c-abl . 336 The Activation of c-abl by the Ph' Translocation . 336 CONCL US ION . 338
Mutations of the CFTR Gene in Idiopathic Pancreatic Hyperenzymemia

Objectives: Idiopathic pancreatic hyperenzymemia is a new syndrome that is characterized by a chronic increase of serum pancreatic enzymes in the absence of pancreatic disease. The aim of this study was to assess whether mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene may have a role in the etiology of this hyperenzymemia. Methods: Seventy subjects with idiopathic pancreatic hyperenzymemia, 44 men and 26 women (mean age, 48 years; range, 8-74 years), were studied. Thirteen of these 70 subjects had the familial form of the syndrome. The mutation analysis of the CFTR gene was carried out using diagnostic commercial kits for the simultaneous detection of 29 mutations and Tn polymorphism. Results: Among the 70 subjects studied, 7 (10.0%) had CFTR gene mutations. None of these 7 subjects had the familial form of pancreatic hyperenzymemia. These mutations were ΔF 508 in 1 subject, 2789 + 5 G > A in another subject, and T5 allele in the remaining 5. All these mutations were heterozygous, with the exception of 1 T5 allele that was homozygous in 1 subject. Conclusions: The frequencies of the mutations of the CFTR gene found in these subjects are similar to the carrier frequencies in the general Italian population. This finding does not support a role for CFTR gene mutations in the etiology of idiopathic pancreatic hyperenzymemia.
The Impact of Institutional Ownership and a Firm's Size on Firm Value: Tax Avoidance As a Moderating Variable

"Objective –The objective of this study is to investigate how institutional ownership and firm size affect firm value. The study also investigates the moderating effect of tax avoidance on the relationship between institutional ownership and the size of a firm on its value. Methodology/Technique –A model was developed and tested using a sample of 66 manufacturing companies listed on the Indonesian Stock Exchange between 2012 and 2014. Findings –The data was collected and analysed using a least square regression and moderated regression analysis. The analysis shows that institutional ownership and firm size affect firm value. The results also indicate that tax avoidance moderates the effect of institutional ownership and that of a firm's size on its value"
Educating for care: a review of the literature.

Given that nursing is a practice-based discipline with care and caring at the core, it can be argued that these two elements should be fundamental concepts within the nursing curriculum. With the ever-increasing use of health care technology it is, however, possible that caring theory as an underpinning concept could be omitted from the curriculum. This literature review explores the issues surrounding student nurses' understanding of what care means to them, and considers the process of conveying the meaning and practice of care to the student nurse. Through reviewing the main theme of Education for Care, the question 'Is it possible to teach "care" to students? ' will be explored.
The Developments on Audit Quality in Indonesia, The Qualitative Analysis on the Practitioners' Expectations

Indonesia has a continuous concerned on its audit quality (AQ) since the impact of global changes on the country’s accounting profession. The data was obtained from face-to-face interviews with practitioners which have given the notion on how far Indonesia has already gone to enhance its AQ. Review of documentary material which was obtained from on the official websites of parties and observation of routine activities of the participants also involved in this study. The discussion of the developments focused on the way to implement AQ conducted by each participant. Institutional analysis was derived directly from data obtained. The findings explained regulators’ roles have created significant efforts to the development on audit quality. In addition, it also shows the implementation of AQ conducted by practitioners in their audit firm. Therefore, those created the expectation of most of practitioners to obtain monetary and nonmonetary value-added impact significantly because of the regulatory efforts. This paper is a contribution to the literature on the subject of AQ by providing the insights into how Indonesia as an emerging country responded to the global demands on AQ improvements and the expectation of the practitioners regarding to the changes. Keywords—Audit Quality, Regulatory Changes, Efforts, Expectation, Practitioner
THE CORRELATION BETWEEN SUSTAINABLE VALUE ADDED AND FINANCIAL PERFORMANCE AMONG INDONESIAN LISTED COMPANIES

Sustainability awareness is growing very fast in the society and companies. A lot of companies do Corporate Social Responsibility (CSR) to satisfy stakeholders, while in return they expect to get a better performance. This research discusses the correlation of sustainability performance to financial performance, by using sustainable value added as a mean of measurement. This measurement monetize the impact of environmental and society performance, so the performance can be measured precisely. This research uses Spearman Correlation to analyze the correlation of thirty-four samples. From this research, it is found that there is correlation between CSR and financial performance
Sleep in High-Functioning Children With Autism: Longitudinal Developmental Change and Associations With Behavior Problems

Sleep disturbance is common in autism spectrum disorder (ASD), but longitudinal trajectories are poorly defined. This study measured sleep disturbance at baseline and 1 year later examining change over time and associated problem behaviors. Participants were 84 gender-matched children, aged between 7 and 12 years at baseline; 46 children were diagnosed with ASD, and 38 were typically developing (TYP) children. Parent reports on a range of scales were collected. The ASD group had more sleep disturbance than the TYP group. Sleep disturbance decreased over the year in children with ASD, but not in TYP children. Reduced sleep disturbance was associated with improved social ability. Sleep disturbance at baseline predicted later anxiety. Findings indicated different trajectories of sleep disturbance in ASD, and the implications are discussed.
Stretching Soil Sampling to Watershed: Evaluation of Soil‐Test Parameters in a Semi‐arid Tropical Watershed

Soil sampling is an integral component of fertility evaluation and nutrient recommendation for efficient use of nutrients in crop production. Little attention has been devoted to evaluating methodology for sampling watersheds under dryland agriculture. A stratified random sampling methodology for sampling the Appayapally watershed in Mahabubnagar district of Andhra Pradesh state in the semi‐arid tropical region of India was adopted and evaluated. The watershed has an area of about 500 ha, with gentle sloping lands (<1% slope), and 217 farmers own land in the watershed. The soils are Alfisols. A total of 114 soil samples were collected from the top 15‐cm layer to represent the entire watershed. Each sample was a composite of 7–8 cores, randomly collected from the area represented by a crop and group of farmers. The soil samples were air dried, ground, and analyzed for pH, electrical conductivity (EC), organic carbon (C), total nitrogen (N), and extractable phosphorus (P), potassium (K), calcium (Ca), magnesium (Mg), sodium (Na), sulfur (S), zinc (Zn), manganese (Mn), iron (Fe), copper (Cu), and boron (B). Statistical analysis of the results on soil fertility parameters showed that the mean‐ or median‐based results of soil tests performed in the study did not differ significantly when the sample set size varied from 5 to 114 (100% of the population). Our results indicate that farmers' fields in the Appayapally watershed are uniform in the chemical fertility parameters studied, and even a small sample set size can represent the whole population. However, such a sampling strategy may be applicable only to watersheds that are very gently sloping and where fertilizer use is very low, resulting in an overall low fertility in the whole watershed.
Equilibrium Isotherms and Kinetic Studies of Removal of Methylene Blue Dye by Adsorption onto Miswak Leaves as a Natural Adsorbent

In this research miswak leaves, agriculture wastes, available in large quantity in Saudi Arabia, was used as low-cost adsorbent for removing methylene blue (MB) dye. Equilibrium behavior of miswak leaves was investigated by performing batch adsorption experiments. The effects of [MB] 0, pH, contact time and adsorbent dose were evaluated. An alkaline pH (10.6) was favorable to the adsorption of MB dye. Adsorption isotherm models, Langmuir, Freundlich and Temkin were used to simulate the equilibrium data. Langmuir equation was found to have the highest value of R2 compared with other models. Furthermore, it was found that miswak leaves have a high adsorptive capacity towards MB dye (200 mg/g) and show favorable adsorption of MB dye with separation factor (RL < 1). In addition, pseudo-first- order, pseudo-second order and intra-particle diffusion were used to study the kinetics of MB adsorption onto miswak leaves. Adsorption process undergoes pseudo-second order kinetic as proved by the high value of R2 and the low value of sum of squared error (SSE percentage). Results indicated that intra-particle diffusion is not the limiting step, and the adsorption process is spontaneous as indicated by the negative value of the .
Anesthetic profile of dexmedetomidine identified by stimulus-response and continuous measurements in rats.

This study characterizes the anesthetic profile of dexmedetomidine on the basis of steady-state plasma concentrations using defined stimulus-response, ventilatory, and continuous electroencephalographic (EEG) and cardiovascular effect measures in rats. At constant plasma concentrations of dexmedetomidine (range, 0.5-19 ng/ml), targeted and maintained by target-controlled infusion, the whisker reflex, righting reflex, startle reflex (to noise), tail clamp response, hot water tail-flick latency, and attenuation of heart rate (HR) increase associated with tail-flick (sympathoadrenal block) and corneal reflex, were assessed in 22 rats. EEG (power in 0.5- to 3.5-Hz frequency band), mean arterial pressure, and HR were recorded continuously. Blood gas values and arterial drug concentrations were determined regularly. The following steady-state plasma EC(50) values of dexmedetomidine (mean +/- S.E. nanograms per milliliter) were estimated: HR decrease (0.51 +/- 0.04), EEG (1.02 +/- 0.08), whisker reflex (1.09 +/- 0.10), sympathoadrenal block (1.85 +/- 0.80), mean arterial blood pressure increase (1.99 +/- 0.44), righting reflex (2.13 +/- 0.15), tail-flick latency (3.65 +/- 0.87), startle reflex (3.75 +/- 0.64), tail clamp (5.49 +/- 1.34), and corneal reflex (24.5 +/- 12.3). At the EC(50) value of tail clamp, ventilatory depression was minor. In rats, dexmedetomidine creates bradycardia, sedation/hypnosis, sympathoadrenal blocking effects, and blood pressure-increasing effects at plasma concentrations below 2.5 ng/ml. Higher plasma concentrations are needed to loose the startle reflex, tail-flick, tail clamp, and corneal reflex responses. Ventilatory depressant effects are minor. The applied EEG measure seems to reflect sedation/hypnosis but seems to have limited value to predict the deeper levels of analgesia and anesthesia of dexmedetomidine.
Ligand‐Induced Folding of the Adenosine Deaminase A‐Riboswitch and Implications on Riboswitch Translational Control

By using a structure‐based fluorescence spectroscopic approach, we have examined the folding of an adenine‐responsive riboswitch that regulates translation initiation. We observed adaptive recognition of the ligand for the aptamer domain of adenosine deaminase (add) mRNA from Vibrio vulnificus, and revealed pronounced conformational changes even in the preorganized loop–loop region that is distant from the binding site. Importantly, the full‐length riboswitch domain, which has a potential translational repressor stem is able to form a binary complex with adenine, and does not act as a folding trap to inhibit binding. The aptamer that is extended by the expression platform therefore remains fully responsive to its ligand; this is in contrast to the previously investigated pbuE A‐riboswitch, which becomes trapped in a nonresponsive terminator fold. Consequently, the latter must employ complex response mechanisms, such as operating in kinetic‐control mode or using transcriptional pausing, to provide time for the aptamer portion to fold and to bind. The different behavior of the riboswitches can be rationalized by their distinct sequence interface between the aptamer and expression platform. For the add A‐riboswitch, our data suggest a thermodynamically driven response mechanism.
ANALISIS PENGARUH UKURAN PERUSAHAAN, PROFITABILITAS, SOLVABILITAS, KUALITAS AUDITOR DAN AUDIT TENURE TERHADAP AUDIT DELAY PADA PERUSAHAAN MANUFAKTUR DI BURSA EFEK INDONESIA PERIODE 2012-2015

The increase of company listed in Capital Market caused demand of financial report auditing by public accountant is getting higher. Companies have obligation to publish their audit financial report to provide information for the external parties, especially investors in determining the investment decision. The sooner the submission of audit financial report, could give good sign fo the investors and late of audit financial report submission caused bad sign for the market. Normally, the investor assume that late submission means bad performance of the company. The period since date of comercial financial report until audit financial report submission refers to the length time of auditing which is call audit delay. There are many factors which are possible to affect the audit delay, such as size of company, profitability, solvency, contingency, audit tenure, and others. This research conducts to research the factors which are affecting audit delay. Variabels as sample on this research are size of company, profitability, solvability, auditor’s quality and audit tenure at manufacturing companies listed on the Indonesia Stock Exchange 2012-2015. The amount of population is 142 companies which become 31 sample by using purposive sampling and 124 observation during 2012 until 2015. The result of this research is profitability, auditor’s quality and audit tenure have negative impact to audit delay. While, company’s size and auditor’s quality have no impact to audit delay. Keywords: audit delay, company size, profitability, solvency, auditor quality, audit tenure
Being high and taking sexual risks: findings from a multisite survey of urban young men who have sex with men.

Adolescent and young adult males who have sex with men (MSM) remain at high risk of HIV infection. Many sexual risk factors have been identified, yet the role of substance use remains controversial. We assess the extent to which urban young MSM report being "high" on drugs or alcohol during sex and the association between being "high" and unprotected anal intercourse (UAI). During summer 2000, 3,075 MSM aged 15-25 years completed a 20-minute interview for the Community Intervention Trial for Youth Project. Participants were asked about their last sexual contact with main and nonmain partners, including whether they were "high on drugs or alcohol. " 18.6% of MSM with a main partner reported being high during their last sexual encounter; 25.0% reported UAI. Among men with a nonmain partner, 29.3% reported being high, and 12.3% reported UAI. Being high was associated with unprotected receptive anal intercourse with nonmain partners (odds ratio = 1.66, p = .02). HIV prevention should include messages about the potential dangers of drinking and drug use in situations where sexual encounters with nonmain partners may occur.