Miracle-dz/UniFAR-FTUs huggingface dataset:
THE IMPACT OF PARENTS ' MEDICATION BELIEFS ON ADHD MANAGEMENT

Adherence behaviour to medication for attention deficit hyperactivity disorder (ADHD) is frequently suboptimal. Parents have several beliefs and experiences about ADHD medication and they going to make their decisions based on that background. This study aims to investigate qualitatively the parental experiences regarding using medication of ADHD for their children with ADHD. A qualitative approach was chosen to gain an in-depth insight into the experiences and beliefs. The investigations approached more than 60 parents during their follow-up. And the final sample included 44 parents. Parents generally were reluctant to medicate their children. Some parents revealed positive experiences about ADHD's medication, mainly when that medication associated with positive performance at their schools. Parents described their hesitancy to continue the medication as a result of having uncertain assessments, side-effects of that medication and stigma. It was rare to hear from parents that behavioural or educational intervention could be used to manage ADHD, mainly when they decide to discontinue medication. There is a need to develop intervention program that educate, encourage, and support parents in following behaviour and pharmacological recommendations.
Yelling at Your TV: An Analysis of Speech Recognition Errors and Subsequent User Behavior on Entertainment Systems

Millions of consumers issue voice queries through television-based entertainment systems such as the Comcast X1, the Amazon Fire TV, and Roku TV. Automatic speech recognition (ASR) systems are responsible for transcribing these voice queries into text to feed downstream natural language understanding modules. However, ASR is far from perfect, often producing incorrect transcriptions and forcing users to take corrective action. To better understand their impact on sessions, this paper characterizes speech recognition errors as well as subsequent user responses. We provide both quantitative and qualitative analyses, examining the acoustic as well as lexical attributes of the utterances. This work represents, to our knowledge, the first analysis of speech recognition errors from real users on a widely-deployed entertainment system.
Serum levels and differential expression of CD44 in childhood leukemia and malignant lymphoma: Correlation with prognostic criteria and survival

Abstract Background : The CD44, a cell surface proteoglycan, participates in a variety of function including tumor dissemination and metastasis. However, there are no available data on the prognostic significance of CD44 expression of tumor tissue correlated with serum sCD44 level in childhood leukemias and lymphomas.
Epistemological Beliefs and their Relations with Conceptions of Learning and Learning Strategies

A questionnaire was administered to 231 teacher education students of a university in Hong Kong to examine their epistemological beliefs, conceptions of learning, and learning strategies. The three variables were measured respectively using the Epistemological Beliefs Scale (EBS) (Chan & Elliott, 2002), Conceptions of Learning Inventory (COLI) (Purdie & Hattie, 2002) and Revised Two Factor Study Process Questionnaire (R-SPQ-2F) (Biggs, Kember, & Leung, 2001). Correlation and path analysis showed significant relations between epistemological beliefs and conceptions of learning and learning strategies. The results suggest the significant roles of epistemological beliefs in learning, through their impact on and relations with the conceptions of learning and strategies adopted by the students. Implications were drawn with suggested ways for further research on their relationships and other metacongitive variables in learning such as achievement or motivation goals. The research findings would provide significant and valuable knowledge in this area and enable a better understanding of the nature and process of learning.
Active Therapy for Chronic Low Back Pain: Part 2. Effects on Paraspinal Muscle Cross-Sectional Area, Fiber Type Size, and Distribution

Design. Randomized prospective study to compare the effects of three types of active therapy on the back muscle structure of chronic low back pain patients. Objectives. To analyze the effects of 3 months active therapy on gross back muscle size and muscle fiber type characteristics and their relationship to changes in muscle function. Summary of Background Data. Many studies have documented a diminished muscular performance capacity in cLBP patients, but few have supported this with evidence of alterations in either the macro- or microscopic structure of the paraspinal muscles. Investigations of the changes in muscle structure following active rehabilitation are even rarer. Methods. Assessments of trunk muscle cross-sectional area (using MRI), erector spinae fiber size/type distribution and pathology (percutaneous biopsy), and muscle function (see Part 1) were made in a group of 59 individuals with cLBP, who were participating in a randomized trial of active therapies for cLBP (physiotherapy, muscle training on devices, aerobics). Results. Fifty-three out of 59 patients (90%) completed the therapy. At baseline, significant correlations were observed between the size of the paraspinal muscles and isometric back extension strength (P =0.0001), and between the proportional area of the muscle occupied by each fiber type and the fatigability of the muscle (P =0.012). Following therapy, there were small (few percent) increases in trunk muscle size in the aerobics and physiotherapy groups and a similarly slight decrease in the devices group. Changes in erector spine size correlated only weakly and nonsignificantly with changes in back extension strength. There were no major changes in fiber type proportion or fiber size in any group following therapy. Conclusion. Three months active therapy is not sufficient to reverse the typical “glycolytic” profile of the muscles of cLBP patients or to effect major changes in backmuscle size. The alterations in muscle performance observed (increased strength and endurance; Part 1) werenot explainable on the basis of structural changes within the muscle.
Development of software on simulation modeling of multi-level information system

The performance study of any software being developed is quite important. This stage is essential in any more or less large-scale project such as development of enterprise-level information systems. To correct the development course it is helpful to have a possibility of analyzing capabilities of the information system being created and obtaining quantitative data of its future performance. Usually, obtaining the information system performance data is possible only after its trial run. Simulation modeling methods fit well the purpose of such studies. The peculiarities of the software applied for simulation modeling include sufficient flexibility in adjusting the mathematical model which represents the information system under development.
A comparison between different selection indexes for milk and udder health traits on Friesian cows in Egypt

A total of 937 normal lactation records of Friesian cows, kept at Sakha Farm, belonging to ministry of Agriculture, Dokki, Cairo Egypt during the period from 1999 to 2004 were used to estimate phenotypic and genetic parameters for 305 day milk yield (305 d MY), lactation period (LP), fat percent (F %) and somatic cell count (SCC). Data were analyzed using Multiple Trait Derivate Free Restricted Maximum Likelihood (MTDFREML). Means of 305 d MY, LP, F % and SCC were 3558 kg, 301 d, 3.7 % and 536 x 10, respectively. Heritability estimates for 305 d MY, LP, F % and SCC were 0.61±0.14, 0.16±0.07, 0.40±0.07 and 0.03±0.07, respectively. Eleven selection indexes were constructed. Index I1 incorporating the four traits was the best (RIH= 0.97).
Ethyl acetate fraction of garlic (Allium sativum) inhibits the viability of MCF7 and HepG2 through induction of apoptosis and G2/M phase cell cycle arrest

© 2018 Amira M. Shaban et al. This is an open access article distributed under the terms of the Creative Commons Attribution License -NonCommercialShareAlikeUnported License (http://creativecommons.org/licenses/by-nc-sa/3.0/). *Corresponding Author Mohammed Abu El-Magd, Anatomy Department, Faculty of Veterinary Medicine, Kafrelsheikh University, Post Box 33516, El-Geish Street, Kafrelsheikh, Egypt. E-mail: mohrizk73 @ yahoo.com; mohamed.abouelmagd @ vet.kfs. edu.eg Ethyl acetate fraction of garlic (Allium sativum) inhibits the viability of MCF7 and HepG2 through induction of apoptosis and G2/M phase cell cycle arrest
Exposure to Pulsed Magnetic Fields Enhances Motor Recovery in Cats After Spinal Cord Injury

Study Design. Animal model study of eight healthy commercial cats was conducted. Objective. To determine whether pulsed electromagnetic field (PMF) stimulation results in improvement of function after contusive spinal cord injury in cats. Summary of Background Data. PMF stimulation has been shown to enhance nerve growth, regeneration, and functional recovery of peripheral nerves. Little research has been performed examining the effects of PMF stimulation on the central nervous system and no studies of PMF effects on in vivo spinal cord injury (SCI) models have been reported. Materials and Methods. PMF stimulation was noninvasively applied for up to 12 weeks to the midthoracic spine of cats with acute contusive spinal cord injury. The injury was produced using a weight-drop apparatus. Motor functions were evaluated with the modified Tarlov assessment scale. Morphologic analyses of the injury sites and somatosensory-evoked potential measurements were conducted to compare results between PMF-stimulated and control groups. Results. There was a significant difference in locomotor recovery between the PMF-stimulated and control groups. Although not statistically significant, PMF-stimulated spinal cords demonstrated greater sparing of peripheral white matter and smaller lesion volumes compared to controls. Somatosensory-evoked potential measurements indicated that the PMF-stimulated group had better recovery of preinjury waveforms than the control group; however, this observation also was not statistically significant because of the small sample size. Conclusions. This preliminary study indicates that pulsed magnetic fields may have beneficial effects on motor function recovery and lesion volume size after acute spinal cord injury.
Pacesetter potential of the human gastroduodenal junction

The pacesetter potential of the gastric antrum and proximal duodenum has been recorded in man by electrodes placed under the serosal coat of the gut. The typical 3 cycle/min of the stomach was found to be conducted across the pylorus into the first part of the duodenum at a rate (2 cm/sec) about four times as fast as its conduction in the more proximal antrum (0·5 cm/sec). A 3 cycle/min pacesetter potential could be detected as far distally in the duodenum as 10 cm from the pylorus.
Lactic dehydrogenase as a biochemical marker of adverse pregnancy outcome in severe pre-eclampsia.

BACKGROUND Pre-eclampsia is a specific disease of pregnancy with multisystem complications. We conducted this study to examine the relationship between lactic dehydrogenase concentration and the severity of the disease and the occurrence of its complications. MATERIAL/METHODS One hundred eleven pre-eclamptic women (49 with mild and 62 with severe pre-eclampsia) and 60 healthy normotensive controls were studied prospectively at the King Hussein Medical Center between January and December 2002. Demographic, hemodynamic, and laboratory data were compared among the three groups. The symptoms and complications of severe pre-eclampsia along with fetal outcome were analyzed according to the levels of LDH (<600, 600-800, and >800 IU/l). One-way analysis of variance (ANOVA) and the chi-square test were used to compare the results. Differences were considered significant when p<0.05. RESULTS The incidence of severe pre-eclampsia was 1.3%. Severely pre-eclamptic patients were significantly younger, with low gravidity and parity. On the other hand, they had significantly increased systolic and diastolic pressure and liver enzymes, uric acid, urine albumin, and LDH levels. The symptoms and complications of pre-eclampsia along with perinatal mortality were increased significantly in patients with LDH >800 IU/l compared with those who had lower levels. CONCLUSIONS Lactic dehydrogenase is a useful biochemical marker that reflects the severity of and the occurrence of complications of pre-eclampsia. Identification of high-risk patients with elevated levels of lactic dehydrogenase, their close monitoring, and prompt, correct management may prevent these complications, with a subsequent decrease in maternal and fetal morbidity and mortality.
Epidemic Content Distribution in Mobile Networks

With the growing popularity of integrating mobile networks and social networks, people now enjoy a freer and more efficient means of communication. Smarter mobile devices facilitate modern human life. In the information age, various new types of information have begun to appear. How to disseminate content to people in a swift and fair way has long been a question. Choosing the right strategy for content distribution is especially crucial for mobile social networks. In this thesis project we use epidemic models for content distribution in mobile social networks. Stochastic mobility models and an SIR epidemic model are set up in the evaluation. We analyze the impact of various parameters of mobility models and epidemic model on content distribution’s success rate and delivery delay. Also, we exploit the social relationships to facilitate content distribution and show the impact of social relationships on content distribution. Simulations have shown that increasing speed and node number in the mobility models will have positive impact on content distribution success rate as well as decreasing the delay. The infect time limit and infect count limit of the epidemic model are also important for swiftly distributing content while considering energy consumption and fairness for nodes. In the social relationship simulation, nodes’ meeting times during a period of time are calculated and a threshold based on a certain level of meeting times is used for categorizing the friendship relationships between nodes. The results show that it will be easier for a successful distribution to be achieved as the social relationship between nodes gets stronger. Also, the delay shows a decreasing trend until reaching the ideal distribution delay time.
Mankin adenosine 2503 in 23 S rRNA The methyltransferase YfgB / RlmN is responsible for modification of

A2503 in 23S rRNA of the Gram-negative bacterium Escherichia coli is located in a functionally important region of the ribosome, at the entrance to the nascent peptide exit tunnel. In E. coli, and likely in other species, this adenosine residue is posttranscriptionally modified to mA. The enzyme responsible for this modification was previously unknown. We identified E. coli protein YfgB, which belongs to the radical SAM enzyme superfamily, as the methyltransferase that modifies A2503 of 23S rRNA to mA. Inactivation of the yfgB gene in E. coli led to the loss of modification at nucleotide A2503 of 23S rRNA as revealed by primer extension analysis and thin layer chromatography. The A2503 modification was restored when YfgB protein was expressed in the yfgB knockout strain. A similar protein was shown to catalyze post-transcriptional modification of A2503 in 23S rRNA in Gram-positive Staphylococcus aureus. The yfgB knockout strain loses in competition with wild type in a co-growth experiment, indicating functional importance of A2503 modification. The location of A2503 in the exit tunnel suggests its possible involvement in interaction with the nascent peptide and raises the possibility that its post-transcriptional modification may influence such an interaction.
Modes of Effective Connectivity within Cortical Pathways Are Distinguished for Different Categories of Visual Context: An fMRI Study

Context contributes to accurate and efficient information processing. To reveal the dynamics of the neural mechanisms that underlie the processing of visual contexts during the recognition of color, shape, and 3D structure of objects, we carried out functional magnetic resonance imaging (fMRI) of subjects while judging the contextual validity of the three visual contexts. Our results demonstrated that the modes of effective connectivity in the cortical pathways, as well as the patterns of activation in these pathways, were dynamical depending on the nature of the visual contexts. While the fusiform gyrus, superior parietal lobe, and inferior prefrontal gyrus were activated by the three visual contexts, the temporal and parahippocampal gyrus/Amygdala (PHG/Amg) cortices were activated only by the color context. We further carried out dynamic causal modeling (DCM) analysis and revealed the nature of the effective connectivity involved in the three contextual information processing. DCM showed that there were dynamic connections and collaborations among the brain regions belonging to the previously identified ventral and dorsal visual pathways.
Echocardiographic study of healthy Indian Spitz dogs with normal reference ranges for the breed

Aim: The present study was aimed to determine the normal reference values of M-mode echocardiographic measurements in healthy Indian Spitz dogs and evaluate the influence of gender and body weight on these measurements. Materials and Methods: M-mode echocardiography was performed in twenty-four clinically healthy conscious Indian Spitz dogs, aged 3-5 years and weighing 7-18 kg. Measurements were made from the right parasternal long axis left ventricular outflow tract view of the heart. The parameters recorded were: Left ventricular internal dimension, interventricular septal thickness and left ventricular posterior wall thickness during diastole and systole, left atrial diameter, aortic root diameter, left ventricular systolic functional parameters, and indices and mitral valve parameters. Results: M-mode echocardiographic measurements in healthy Indian Spitz dogs were standardized. Gender had no influence on echocardiographic measurements except mitral valve excursion amplitude and time interval between onset and end of mitral valve closure, which were significantly (p<0.05) higher in females than males. Left ventricular internal dimension at end-diastole, left ventricular internal dimension at end-systole, left ventricular posterior wall dimension at end-systole, end-diastolic volume, end-systolic volume, stroke volume, cardiac output, left ventricular ejection time, and mitral valve excursion amplitude correlated significantly (p<0.05) with body weight in Indian Spitz dogs. Conclusion: Data obtained in the present study can be used as breed-specific reference values for cardiac disease diagnosis as well as for future studies in Indian Spitz dogs.
Mutation segregation and rapid carrier detection of X-linked muscular dystrophy in dogs.

OBJECTIVES To use exon 7-specific genomic polymerase chain reaction (PCR) products to identify the genotypes of normal, affected, and carrier female dogs in pedigrees segregating Golden Retriever muscular dystrophy (GRMD), and to confirm the concordant segregation of the mutation in all carrier and affected dogs presently available. DESIGN The GRMD mutation is found in the consensus splice acceptor site in intron 6 of the canine dystrophin gene. PCR cycle-sequencing and restriction fragment length polymorphism/PCR were used for determination of the pattern of segregation of the point mutation which causes GRMD. ANIMALS Normal, clinically affected, and obligate carrier dogs in pedigrees of GRMD. PROCEDURE DNA from blood was amplified, using PCR and primers that bracket all of exon 7 of the canine dystrophin gene as well as 100 base pairs of intron on either side. PCR products were either cycle-sequenced directly or submitted to a second round of PCR, using 1 of the original primers coupled with a mutagenic restriction fragment length polymorphism-primer, which thus creates an artificial restriction site. Digestion with Stu I detected the normal allele. To detect the affected allele, Sau96 I was used to digest the 310-base pair exon 7 genomic fragment directly. CONCLUSIONS Simple, clear diagnosis of carrier status was possible using these methods. This mutation is passed through all carrier and affected dogs in both United States GRMD colonies and the colony in Australia. CLINICAL RELEVANCE Rapid, accurate diagnosis of carrier and affected dogs will enhance study of this homologue of Duchenne muscular dystrophy.
Vitamin Supplementation: What The Gastroenterologist Needs To Know

Background: The vitamin business is a multimillion dollar industry. Aggressive marketing strategies are used to make claims for the health benefits of these products. Observational studies suggest that people who consume vitamin supplements decrease their risks for cancer, cardiovascular disease, and gastrointestinal disease. What is the evidence for these claims, and as a prescribing gastroenterologist, is there a scientific basis for vitamin supplementation? Methods: A narrative review focusing on randomized controlled trials, where available, plus observational studies obtained from personal files, "on-line" searches, and references in reviewed articles. Results: From the perspective of a gastroenterologist, there is strong evidence to recommend B12 supplementation in gastric and intestinal disease, as well as pernicious anemia. There exists moderate evidence to support B12 supplements in pancreatic disease. Vitamin D and calcium supplementation are recommended for persons with disorders of malabsorption, cholestasis, and illnesses requiring chronic steroids. Only observational studies suggest a correlation between vitamin D/calcium and decreased colorectal adenoma recurrence. Although folic acid supplementation is beneficial in persons on medications such as methotrexate and sulfasalazine, studies are contradictory with regard to folic acid and colon cancer prevention. Overall, antioxidants have not been proven to decrease the risk for colorectal adenoma, gastric cancer, or esophageal cancer. Conclusions: Observational studies do not correlate with randomized clinical trials; therefore, few definitive recommendations can be made. Vitamin supplements are appropriate for recognized deficiencies; however, there is a lack of evidence to support their effects in the prevention of chronic disease.
Apolipoprotein E Polymorphism and Serum Concentration in Alzheimer's Disease in Nine European Centres: the ApoEurope Study

Abstract As part of the ApoEurope Project, apolipoprotein E (apo E) common polymorphism and serum concentration were determined in 489 Alzheimer's disease patients and 429 controls. Patients and controls were recruited through nine centres in eight European countries. Age, sex ratios and education levels of both case and control populations were similar, although discrete differences appeared between centres. The prevalence of the ε4 allele was higher in Alzheimer's disease than in controls (increased by 140%), while serum apo E concentration was lower by 11.2% (p<0.001). In addition, serum total cholesterol and triglyceride concentrations were lower in Alzheimer's disease (p<0.001), while that of apo AI was not affected. The decrease in serum apo E concentration was not accounted for by the ε4 allele, age or gender, suggesting that apo E concentration might represent an additional risk factor for Alzheimer's disease, complementary and independent of the ε4 allele. Further analysis will be aimed at determining whether the quantitative link between apo E concentration and Alzheimer's disease occurs through the effect of apo E genotype on lipid parameters or by other mechanisms.