Miracle-dz/UniFAR-FTUs huggingface dataset:
Sustainability Reporting By Universities In Indonesia Abstract

Abstract: This study aims to describe sustainability reporting practices by universities in Indonesia by knowing the reporting channel used by universities and the conformity of information disclosure with GRI G4 indicator and campus sustainability assessment instrument. This study uses a framework with 73 indicators based on GRI and a campus sustainability assessment instrument to analyze information disclosed by universities in Indonesia. The results of the analysis show that the level of disclosure of sustainability information conducted by universities in Indonesia is lower when compared with universities in Canada and Lithuania. Disclosure of information undertaken by universities in Indonesia remains limited in scope, and no universities disclose sustainability information in an integrated report. Abstrak: Penelitian ini bertujuan untuk mendeskripsikan praktik pelaporan keberlanjutan oleh perguruan tinggi di Indonesia dengan mengetahui saluran pelaporan yang digunakan oleh universitas dan kesesuaian pengungkapan informasi dengan indikator GRI G4 dan instrumen penilaian keberlanjutan kampus. Penelitian ini menggunakan kerangka kerja dengan 73 indikator berdasarkan GRI dan instrumen penilaian keberlanjutan kampus untuk menganalisis informasi yang diungkapkan oleh universitas di Indonesia. Hasil analisis menunjukkan bahwa tingkat pengungkapan informasi keberlanjutan yang dilakukan oleh universitas di Indonesia lebih rendah bila dibandingkan dengan universitas di Kanada dan Lithuania. Keterbukaan informasi yang dilakukan oleh universitas di Indonesia masih terbatas dalam ruang lingkupnya, dan tidak ada universitas yang mengungkapkan informasi keberlanjutan dalam laporan terpadu.
Adherence of Candida albicans to endothelial cells is inhibited by prostaglandin I2

The adherence of Candida species yeast cells to bovine and human endothelium was measured. The adherence phenomenon is a saturable event which can be altered by the release of prostaglandin I2 (PGI2 or prostacyclin) by endothelial cells. Release of PGI2 by endothelium has a protective effect, reducing Candida albicans yeast cell adherence to endothelial cells in a dose-dependent manner. Conversely, C. albicans appears to inhibit the release of PGI2 by endothelial cells and thus perhaps is capable of increasing the number of yeast cells which adhere to endothelium. Furthermore, a long-acting analog of PGI2, carbacyclin, reduced the number of yeast cells adhering to human platelet aggregates. Thus, it is possible that the release of PGI2 by endothelium has a protective effect against the hematogenous dissemination of C. albicans and its ability to adhere to vascular endothelium and fibrin-platelet matrices.
Faulty radiographs: A cross-sectional analysis among dental college students in Namakkal District, Tamil Nadu, India

Aim: The aim of this study was to assess the ability of taking and processing of intraoral periapical radiographs (IOPA) by the dental college undergraduate students and also to evaluate the impact of teaching on their skills. Materials and Methods: This study was conducted in the OMRD department. Final year students (52) and interns (41) of 2014 were included in this study. In this 1 year study, 13104 IOPAs were taken and manually processed by these students. These radiographs were evaluated by two senior faculties of the department separately. To check variability between two examiners, ANOVA test was performed and all data were analyzed using WINDOW'S SPSS version 12 (Microsoft, USA). Results: Of 13104 IOPAs, 3538 were considered as faulty radiographs, of this 26.1% cone cut which occupies the first position and was followed by improper vertical angulation (25.2%), film position error (23.2%), improper horizontal angulation (13.1%), processing errors (9.5%), and miscellaneous such as reversed film, film bending (2.9%). Conclusion: Considering the statistical analysis by increasing experience, students make fewer numbers of errors.
Inhibition of Gap Junctional Intercellular Communication and Activation of Mitogen-Activated Protein Kinase by Tumor-Promoting Organic Peroxides and Protection by Resveratrol

Abstract Dicumyl peroxide (di-CuOOH) and benzoyl peroxide (BzOOH) act as tumor promoters in SENCAR mice, whereas di-tert-butylhydroperoxide does not. Tumor promotion requires the removal of growth suppression by inhibition of gap junctional intercellular communication (GJIC) and the induction of mitogenic intracellular pathways. We showed that di-CuOOH and BzOOH both reversibly inhibited GJIC and transiently activated mitogen-activated protein kinase, specifically, the extracellular receptor kinase at noncytotoxic conditions in WB-F344 rat liver epithelial cells, whereas the non–tumor-promoting di-tert-butylhydroperoxide did not inhibit GJIC or activate extracellular receptor kinase. di-CuOOH but not BzOOH inhibited GJIC through a phosphatidylcholine-specific phospholipase C–dependent mechanism. N-Acetylcysteine (NAC) was needed to prevent a cytotoxic, glutathione-depleting effect of BzOOH, whereas di-CuOOH was noncytotoxic and did not alter glutathione levels at all doses and times tested. Pretreatment of WB-F344 cells with resveratrol, a polyphenolic antioxidant present in red wine, prevented at physiological doses the inhibition of GJIC by di-CuOOH but not from BzOOH and was effective in significantly preventing extracellular receptor kinase activation by both peroxides. NAC did not prevent any of the peroxide effects on either GJIC or extracellular receptor kinase, suggesting a specific antioxidant effect of resveratrol.
Seroepidemiology of human herpesvirus 7 in healthy children and adults in Japan

The isolation of human herpesvirus 7 (HHV‐7) from saliva and blood, and the prevalence of antibodies to the virus in healthy individuals were investigated in Japan. By cocultivating samples with phytohemagglutinin‐P‐stimulated cord blood mononuclear cells, HHV‐7 was isolated from the saliva of 1 of 20 children and from 4 of 38 adults but not from their blood. The isolates were confirmed as closely related to RK strain of HHV‐7, but not to U1102 (human herpesvirus 6, HHV‐6 type A) or Z29 (HHV‐6 type B) strains by restriction cleavage patterns of the DNA. The virus antibody of 330 healthy children and adults was measured with an indirect immunofluorescence assay, using one of our isolates (FG7‐6). The positivity rate of antibody was 40% in the first 2 months of life, declined during the first 6 months, then gradually increased and was 45% at 1‐4 years of age. It reached the highest level (60%) at 11‐13 years of age and was maintained until the end of the third decade, then decreased thereafter. Additionally, no simultaneous rise in the antibody titers was observed in 7 virologically confirmed exanthem subitum patients.
Health anxiety and fear of fear in panic disorder and agoraphobia vs. social phobia: a prospective longitudinal study

Background: This study is aimed to evaluate the role of two vulnerability factors, health anxiety and fear of fear, in the prediction of the onset of panic disorder/agoraphobia (PDA) relative to a comparison anxiety disorder. Methods: Young women, aged between 18 and 24 years, were investigated at baseline and, 17 months later, using the Anxiety Disorders Interview Schedule‐Lifetime and measures of health anxiety and fear of bodily sensations (subscale disease phobia of the Whiteley Index, and total score of the Body Sensations Questionnaire). First, 22 women with current PDA were compared to 81 women with current social phobia and 1,283 controls. Second, 24 women with an incidence of PDA were compared to 60 women with an incidence of social phobia and 1,036 controls. Results: Multiple logistic regression analyses adjusted for history of physical diseases, somatic symptoms, and other psychological disorders revealed that (a) fear of bodily sensations was elevated for women with PDA vs. controls as well as women with social phobia, and (b) health anxiety (and history of physical diseases) was elevated in women who developed PDA vs. controls and vs. women who developed social phobia. Conclusions: These results suggest that health anxiety, as well as history of physical diseases, may be specific vulnerability factors for the onset of PDA relative to social phobia. Whereas fear of bodily sensations was not found to be a risk factor for the onset of panic disorder/agoraphobia, it was a specific marker of existing PDA relative to social phobia. Depression and Anxiety, 2010. © 2010 Wiley‐Liss, Inc.
A model of political leadership characteristics leading to country development

At present, overall dimensions of leadership quality in Thailand tend to decrease dramatically. When considering political context in Thailand, it was found that Thailand is facing crisis in political leadership. This study aimed to investigate political leadership characteristics leading to country development and to develop a structural equation model. The researchers collected qualitative data by interviewing experts in the field and collecting quantitative data by interviewing 500 political leaders at the local and national levels. The data analysis yielded the political leadership model consisted of 5 aspects; namely, Interpersonal Building related to thinking and implementing projects beneficial to society at large; Individualized Consideration in relation to utilizing personnel according to their ability; Intelligence concerning having ability to analyze problems and having courage to make right decisions in every situation; Integrity involving loving and being faithful to the nation, religion, the king and the organization; Interpersonal Attribution including persistence, devotion and sacrifice. After testing the hypotheses, it was found that political leaders at the national and local levels differently emphasized overall leadership characteristics for country development. The analysis of the structural equation model developed by the researcher revealed that the model passed the assessment criteria and accorded with the empirical data with Chi-square value of 0.722, relative Chi-square value of 0.948, IOC value of 0.961, and RMSEA of 0.000. The hypotheses testing of the model showed that Intelligence had direct effect on Interpersonal Building, while Integrity had direct effect on Intelligence and Interpersonal Building. However, Interpersonal Building had direct effect on Individualized Consideration and Interpersonal Attribution also had direct effect on Integrity. The statistical significance level of this study was set at 0.05. Corresponding author: Sathit Pitutecha Email addresses for the corresponding author: sunee.w@fba.kmutnb. ac.th First submission received: 3rd April 2018 Revised submission received: 5th June 2018 Accepted: 17th August 2018
Spatial disorientation as an early symptom of Parkinson's disease

In 44 consecutive outpatients with idiopathic Parkinson's disease (PD) without levodopa substitution therapy, we tested spatial orientation. Spatial orientation was impaired on the rod orientation test in 43 patients, on the line orientation test in 7 patients, and on the facial recognition test in 17 patients. There was no correlation between severity of spatial disorientation and age, length of illness, verbal WAIS score, or severity of PD. Impairment of spatial orientation is part of PD even in mild cases.
Predictive Duty Cycle Control of Three-Phase Active-Front-End Rectifiers

This paper proposed an online optimizing duty cycle control approach for three-phase active-front-end rectifiers, aiming to obtain the optimal control actions under different operating conditions. Similar to finite-control set model predictive control strategy, a cost function previously constructed based on the desired control performance is adopted here, which is essential for the solving process of the optimizing problem. On the other hand, differently, with respect to the proposed strategy, duty cycle signals are optimized, instead of possible switching states. The determination of optimal duty cycles is made by predicting the effect of duty cycles on instantaneous current variations and minimizing the cost function. Due to the adoption of behavior prediction, the proposed controller inherits the excellent dynamic characteristics of predictive controllers. Moreover, the application of optimal duty cycles determined by cost function minimization automatically ensures optimum operations of converters within each sampling period. Improved transient and steady-state features of the proposed strategy are confirmed by experimental validations and in-depth comparisons with linear controllers, deadbeat predictive controllers, and finite-control set model predictive control strategies.
Interferon-Γ Release Assays for the Diagnosis and Mycobacterium Tuberculosis Infection in Children: A Systematic Review and Meta-Analysis

Data regarding the use of Interferon-gamma release assays (IGRAs) for tuberculosis diagnosis are accumulating. We systematically searched PubMed, EMBASE and Cochrane and performed pooled estimates of sensitivity and specificity of QuantiFERON-TB Gold In Tube (QFT-G-IT) and T-SPOT. TB compared to tuberculin skin test (TST). For studies assessing sensitivity, children had to have active tuberculosis. Specificity data were derived from children classified as non-infected. Eleven studies were included in the sensitivity analysis for TST, 10 for QFT-G-IT, and 9 for T-SPOT.TB. Eight studies were included in specificity analysis for TST, 8 for QFT-G-IT, and 7 for T-SPOT.TB. Pooled QFT-G-IT sensitivity was 0.79 (95%CI:0.70–0.89) pooled T-SPOT.TB sensitivity was 0.74 (95%CI:0.59–0.90) and pooled TST sensitivity was 0.82 (95%CI:0.72–0.93). Pooled QFT-G-IT and T-SPOT.TB specificities were 0.95 (95%CI:0.93–0.97) and 0.96 (95%CI:0.93–1.00), respectively. Pooled TST specificity was significantly lower 0.83 (95%CI:0.74–0.92). IGRA performance in children showed no better sensitivity than TST, but higher specificity.
A Survey of G6 and G10 Serotypes of Group a Bovine Rotaviruses from Diarrheic Beef and Dairy Calves using Monoclonal Antibodies in ELISA

Group A bovine rotaviruses (BRV) have been identified worldwide as a major cause of diarrhea in the young of many species, including humans. Group A rotaviruses are classified into serotypes on the basis of the outer capsid proteins, VP7 (G types) and VP4 (P types). To date, there are 14 G types of group A rotaviruses, with G1, G6, G8, and G10 described for BRV isolates. In this study, G6- and G lo-specific monoclonal antibodies (MAbs) were used in an enzyme-linked immunosorbent assay (ELISA) for the G typing of BRV-positive stool samples from diarrheic beef and dairy calves from South Dakota, Ohio, Michigan, Nebraska, and Washington, USA, and Ontario, Canada. ELISA plates were coated using a broadly reactive VP7 MAb (Common 60) or with G6- or G10-specific MAbs. BRV-positive fecal samples were diluted and added to duplicate wells, followed by the addition of polyclonal guinea pig anti-group A rotavirus serum as the secondary antibody. Several reference G6 and G10 BRV strains as well as other G types previously reported in cattle (G1, G2, G3, G8) and BRV-negative samples were included as G type specificity and negative controls. From a total of 308 field samples analyzed, 79% (244/308) tested positive by the broadly reactive VP7 MAb; of these, 54% (131/244) were G6 positive, 14% (35/244) were G10 positive, 4% (9/244) were both G6 and G10 positive, and 28% (69/244) were G6 and G10 negative. The negative samples may represent additional or undefined serotypes. The 89 samples from South Dakota were further subdivided into samples from beef (n = 43) or dairy (n = 46) herds. G6 was more prevalent in beef herd samples (67%) than in dairy herd samples (47.5%). In addition, dairy herds had higher percentages of G10-positive samples (17.5%) G6-G10 double positives (10%), and untypable samples (25%) than did beef herds, in which the prevalence of G10 positive samples was 5.5%, G6-G10 double positives was 5.5%, and untypable samples was 22%. Application of the serotype ELISA for the analysis of additional BRV samples will provide further epidemiologic data on the distribution of BRV serotypes in beef or dairy cattle, an important consideration for the development of improved BRV vaccines.
Deletion of chromosome 21 disturbs human brain morphogenesis

Purpose: Humans with small deletions of chromosome 21 provide important models for understanding the role of dosage-sensitive genes in brain morphogenesis. To identify chromosome 21 genes responsible for defects of the central nervous system, we determined the deleted regions and brain malformations in three unrelated individuals with overlapping partial deletions of chromosome 21.Methods: Fluorescent in situ hybridization and magnetic resonance imaging were used to define the chromosomal structure and structural brain abnormalities present in these three individuals.Results: The regions of chromosome 21 found to be deleted in these individuals were as follows: case 1: KCNJ6 to the telomere; case 2: ITSN1 to the telomere; and case 3: ITSN1 to PCNT2. The abnormalities of brain structure shared by all included microcephaly, pachygyria, polymicrogyria, colpocephaly, hypoplastic corpus callosum and white matter, hypoplastic cerebellum, and enlarged ventricular system. The clinical features in common included mental retardation, microcephaly, facial dysmorphism, and epilepsy (severe in one patient). Conclusion: From analyses of the molecular, cytogenetic, and neuroimaging data from these three individuals, combined with those from previously reported cases, we infer that deletion of an 8.4-Mb region in chromosome band 21q22.2-22.3 (KCNJ6-COL6A2) is associated with cortical dysplasia. We propose that one or more dosage-sensitive genes in this region contributes to cortical development and that deletion of 21q22.2-22.3 should be considered in the diagnosis of mentally retarded patients with facial dysmorphism and cerebral dysplasia.
Improved survival with highly active antiretroviral therapy in HIV-infected patients with severe Pneumocystis carinii pneumonia

Background: Although the incidence of Pneumocystis carinii pneumonia (PCP) has declined, mortality of patients who require intensive care for this disease remains high. Highly active antiretroviral therapy (HAART) might alter the course of PCP either via effects on the immune system or through anti-Pneumocystis actions; however, HAART has not been studied in patients acutely ill with PCP. Objective: To assess the effects of HAART on outcome of patients admitted to the intensive care unit (ICU) with PCP. Design and setting: Retrospective cohort study carried out at a University-affiliated county hospital. Participants: Fifty-eight HIV-infected adults with PCP admitted to an ICU from 1996 to 2001. Measurements: A standardized chart review was performed to collect information on demographic variables, hospital course, and use of antiretroviral therapy. Outcome measured was death while in the ICU or hospital. Results: A total of 20.7% of patients were either receiving HAART or were started on therapy while hospitalized. Mortality in this group was 25%, whereas mortality in those not receiving therapy was 63% (P = 0.03). Multiple logistic regression analyses adjusting for potential confounders showed that HAART started either before or during hospitalization was associated with a lower mortality [odds ratio (OR), 0.14; 95% confidence interval (95% CI), 0.02–0.84; P = 0.03). The need for mechanical ventilation and/or development of a pneumothorax (OR, 20.9; 95% CI, 1.9–227.2; P = 0.01) and delayed ICU admission (OR, 9.7; 95% CI, 2.2–42.1; P = 0.002) were associated with increased mortality. Conclusions: Use of HAART is an independent predictor of decreased mortality in severe PCP and may represent a potential therapy to improve outcome in this disease.
Are Evoked Potentials in Patients With Adult-Onset Pompe Disease Indicative of Clinically Relevant Central Nervous System Involvement?

Purpose: Pompe disease is a multisystem autosomal recessive glycogen storage disease. Autoptic findings in patients with classic infantile and late-onset Pompe disease have proven that accumulation of glycogen can also be found in the peripheral and central nervous system. To assess the functional role of these pathologic findings, multimodal sensory evoked potentials were analyzed. Methods: Serial recordings for brainstem auditory, visual, and somatosensory evoked potentials of 11 late-onset Pompe patients were reviewed. Data at the onset of the enzyme replacement therapy with alglucosidase alfa were compared with follow-up recordings at 12 and 24 months. Results: Brainstem auditory evoked potentials showed a delayed peak I in 1/10 patients and an increased I–III and I–V interpeak latency in 1/10 patients, respectively. The III–V interpeak latencies were in the normal range. Visual evoked potentials were completely normal. Median somatosensory evoked potentials showed an extended interpeak latency in 3/9 patients. Wilcoxon tests comparing age-matched subgroups found significant differences in brainstem auditory evoked potentials and visual evoked potentials. Conclusions: We found that the majority of recordings for evoked potentials were within the ranges for standard values, therefore reflecting the lack of clinically relevant central nervous system involvement. Regular surveillance by means of evoked potentials does not seem to be appropriate in late-onset Pompe patients.
Predictors for non-adherence to antiretroviral therapy.

OBJECTIVES To determine the risk factors for non-adherence to antiretroviral therapy. METHODS Two hundred clients attending the Melbourne Sexual Health Centre completed a questionnaire about lifestyle, self-efficacy, depression, drug or alcohol use, social supports, and attitudes to health care. Self-reported adherence (SRA) was measured by missed doses in the last 4, 7 and 28 days. Routinely collected viral load levels were reviewed. RESULTS Two hundred (85%) out of 231 eligible clients participated in the study. Viral load was most strongly associated with SRA for the last 28 days (P < 0.001). Non-adherence was defined as <98.2% SRA. Non-adherence was most strongly associated with having regular daily routines [odds ratio and 95% confidence interval = 0.4 (0.2, 0.7)], having set times for getting up and going to bed [0.5 (0.3, 1.0)], using marijuana more than 4 times per week [0.4 (0.2, 1.0)] and lower self-efficacy which included; being sure that you will be able to take medications as directed [0.2 (0.1, 0.6)] and being sure that missing doses of HIV medication will result in drug resistance [0.4 (0.2, 0.7)]. When significant questions were combined into a composite score to screen for non-adherence, the sensitivity to predict non-adherence was as high as 71% with a specificity of 59%. CONCLUSIONS This study showed that a 10-min questionnaire was associated with clients past non-adherence to antiretroviral therapy and may be useful for predicting future adherence.