Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparative Study to Evaluate Efficacy, Safety and Quality of Life of Metoprolol and Telmisartan versus Metoprolol and Ramipril in Patients of Hypertension

Background: Hypertension(HTN) is a major cardiovascular disease and is a major worldwide clinical problem. The prevalence of hypertension increases in urban and rural areas. The treatment of hypertension began in the 1960s with oral diuretics. The other modalities of treatment of hypertension are beta – blockers, calcium-channel blockers, alphareceptors blockers, ACE inhibitors and ARBs. The better compliance occurs with single-pill combination, and may be even double or even triple pill combination therapy should be used. Also quality of life was improved better with Metoprolol and Telmisartan as compared with Metoprolol and Ramipril. Quality of life was assessed by SF -36 Quiestionnare. Objective: To compare the effect of Metoprolol and Telmisartan versus Metoprolol and Ramipril on BP and quality of life in patients of hypertension. Material and Methods: In this prospective, open, randomized, parallel group, comparative study, 80 patients of hypertension attending the Cardiology Outpatient Department, Govt. Medical College & Rajindra Hospital, Patiala were recruited. This randomized comparative study was done on 80 patients for 4 months. Quality of Life: In my project of Quality of life, I had taken total 80 patients and the patients were divided into two groups and 40 patients each of Metoprolol and Ramipril versus Metoprolol and Telmisartan. To assess quality of life questionnaire SF-36 was administered to the patients. Results: There was a marked decrease in SBP and DBP with the use of Metoprolol and Telmisartan than Metoprolol and Ramipril. There was also no change in demographic parameters. There was significant improvement in the quality of life with Metoprolol and Telmisartan. Conclusion: Metoprolol and Telmisartan was a better choice than Metoprolol and Ramipril in treating hypertension as this combination causes more reduction in BP and little effect on HR.
Performance Analysis of Ad Hoc Routing Protocols

Routing is the method of selecting appropriate path in a network while sending packets from source to destination. Mobile ad hoc network is very popular domain of research due to their ad hoc nature. Ad hoc networks are wireless network with no infrastructure support. Due to the limited transmission range of wireless network interfaces, multiple network hops may be needed for nodes to exchange data across the network. In such a network, each mobile node operates not only as a host but also as a router, forwarding packets for other mobile nodes in the network that may not be within the direct reach. Routing protocols developed for wired networks such as the distance vector or link state protocols are inadequate here as they not only assume mostly fixed topology but also have high overheads. This has lead to several routing algorithms/proposals specifically targeted for ad hoc networks. While some of these proposals are optimized variants of protocols originally designed for wired networks, the rest adopt new paradigms such as proactive or on demand routing. In this paper, we include the MANET supported routing protocols and perform their performance analysis over different performance parameters such as packet delivery ratio and delay etc.
Diagnostic Accuracy Of Ripasa Score.

BACKGROUND Acute appendicitis is one of the most common acute surgical emergencies on emergency room floor and timely diagnosis of the condition is of utmost importance. Multiple diagnostic Score exist to help in the clinical diagnosis; among Which RIPASA is a recent introduction. METHODS The study was carried out Ayub Teaching hospital of Abbottabad from Sept-2017 to Feb-2018, Department of General Surgery. The ultimate decision to perform surgery was not guided by the scores and the surgeon's decision was the final word, and specimens were sent afterward for histopathology. The results compiled and entered into SPSS 20. RESULTS Out of the 308, 288 patients underwent surgery for AP, 165 (57.3%) were male and 123 (42.7%) were female, 252 (87.5%) had positive histopathology report and 36 (12.5%) had a negative report, with resultant negative appendectomy rate of 12.5% well below the average. 26 (9.02%) had a perforated appendix and 8 (2.8%) had post-op wound infection. The sensitivity of RIPASA score at a cut-off value of 7.5 was 98.02%, with specificity of 75%, and Positive Predictive Value of 96.48%, and Negative Predictive Value of 84.7%. Compared to Alvarado's Score Sensitivity and Specificity of 53% and 75% respectively. CONCLUSIONS On the balance the RIPASA Score detects early preventing from dreadful complication and in turn have low specificity giving way to a slightly higher negative appendectomy rate with the consequent morbidity and mortality of unnecessary surgery. Still RIPASA Score outperforms the Alvarado and Modified Alvarado Score.
Transfer Cost of Virtual Machine Live Migration in Cloud Systems

Virtualized frameworks typically form the foundations of Cloud systems, where Virtual Machine (VM) instances provide execution environments for a diverse range of applications and services. Normally, modern VMs support Live Migration (LM) – a feature wherein a VM instance is transferred to an alternative node without stopping its execution. The focus of this research is to assess the cost of the total network usage required to complete a LM process. The paper describes four major areas of the LM transfer process – CPU registers, memory, permanent storage and network switching – and analyses their impact on the size of the migrated data. We also introduce a Live Migration Data Transfer (LMDT) formula, which can be successfully used for estimation purposes. Finally, the paper describes a series of experiments which were performed for LMs of VM instances within an isolated network, before discussing the subsequent outcomes and conclusions.
Epidemiology, Clinical and Paraclinical Presentations of Pulmonary Embolism: A Cross-Sectional Study in a Sub-Saharan Africa Setting

Background: Venous thromboembolic (VTE) disease burden is increasing worldwide, representing a major cause of cardiovascular death and public health problem. Pulmonary embolism (PE) is the most serious clinical presentation of VTE. Epidemiological and clinical data on PE are still lacking in Africa, particularly in Cameroon. This study aimed at determining the clinical features as well as imaging presentation and outcome of pulmonary embolism. Methods: A cross-sectional study was carried out in three hospitals in Douala. We retrospectively reviewed patient records admitted for PE from January 2009 to May 2017. We collected data on epidemiology, clinical presentation, venous Doppler/pulmonary computed tomographic angiography (CTA), and outcome. Results: We included 103 patients (56 males) with PE. Their median age was 52 years. The main risk factors were obesity (49.5%), hypertension (35.0%), long trip (24.3%) and cancer (18.4%). The most frequent clinical presentations were dyspnoea (83.4%), chest pain (78.6%), and cough (40.8%). Additionally, pleural effusion (32.8%), atelectasis (25.7%) and pulmonary hyperlucency (20.0%) were the most frequent findings on chest X-ray. The main abnormalities found in electrocardiogram were sinus tachycardia (63.4%), S1Q3T3 aspect (37.6%) and right axial deviation (28.7%). Moreover, right cavities dilatation (26.0%), pulmonary artery hypertension (35.0%) and pulmonary artery dilatation (21.0%) were the main echocardiographic findings. Low-molecular-weight heparin (LMWH) was the initial anticoagulant in all cases. There were 19 (18.4%) in-hospital deaths, and the mean hospital stay was 8.5 ± 5 days. Conclusion: PE is not rare in our setting. Obesity, long trip and cancer are the main risk factors, while dyspnoea, chest pain and respiratory distress are the main clinical presentation for PE. LMWH remains the therapeutic agent of choice. Lastly, in-hospital mortality is very high.
Genetic association between antipsychotic induced weight gain and FTO gene in a Sri Lankan population

Background About 30% of patients treated with second generation antipsychotics (SGA) experience weight gain. Although there is evidence that the FTO gene is associated with obesity its role in antipsychotic induced weight gain is not so clear. Methods A genetic association study was carried out to identify the association between FTO rs9939609 and antipsychotic induced weight gain. Sample consisted of 180 cases and 120 controls. Cases were patients diagnosed with schizophrenia or schizoaffective disorder, treated with second-generation antipsychotics for a minimum of 3 months, and had gained at least 10% of body weight. Controls were patients with schizophrenia treated with second-generation antipsychotics for a minimum of 3 months but had not gained ≥10% of body weight. Genomic DNA was extracted from whole blood. Polymerase chain reaction of the samples was done. Real-time quantitative PCR (qPCR) was carried out using BIO-RAD CFX96 Touch TM PCR detection system. Results Females were significantly more among cases (58.3%) than controls (35%). Cases (52.4%) were significantly more likely to be overweight or obese than controls (13.8%). Genotype distribution was in Hardy-Weinberg equilibrium (p=0.43). Cochran-Armitage trend test was not significant. Risk of antipsychotic induced weight gain in the AA genotype [OR 1.69 (95% CI 0.74-3.86)] and AT genotype [OR 1.1 (95% CI 0.67-1.79)] were not significantly higher than the TT genotype. Recessive model showed that AA/AT genotypes were at significantly higher risk of being obese/overweight [OR 1.84 (95% CI 1.05-3.2)]. Conclusions There was no significant association between FTO rs9939609 and antipsychotic induced weight gain. AA/AT genotypes had significantly higher risk of overweight/obesity.
Increasing Utilization of Cognitive Behavioral Therapy to Reduce Morbid Obesity in a Primary Care Setting

Background: Obesity among adults is characterized by a body mass index (BMI) of 30 or higher. The impairment and disability resulting from obesity indicates a significant health problem that is often seen in primary care settings. Research indicates that cognitive behavioral therapy (CBT) is an underutilized, but extremely beneficial intervention that may support individuals in achieving weight loss. Adults suffering from obesity with or without comorbid conditions such as psychiatric disorders (e.g. anxiety and depression) have benefitted from CBT. Purpose: To implement the increased utilization of CBT in the adult population with obesity and depression or anxiety in a primary care setting. Methods: Based on an extensive review of literature, a project was designed and conducted to increase knowledge and utilization of CBT by health care providers for the treatment of obesity. Outcome evaluation was based on post-implementation questionnaire and data regarding number of referrals made to the in-office cognitive behavioral therapist. Results: Results include an increased understanding, by health care providers of CBT use for treatment of obesity, and an increased number in referrals to the cognitive behavioral therapist. Conclusion: Delivering health care providers information about CBT increased their likelihood to recommend and place referrals to the in-office cognitive behavioral therapist for future patients with BMI of 30 or greater.
Psychosocial Issues Experienced by Parents of Children with Cancer in Southern Nigeria

Background: Childhood cancers have been on the rise globally. Parents of affected children have to cope with pressures and stresses of treatment often associated with a significantly increased risk of psychosocial issues. Objectives: To explore the experiences and psychosocial issues of parents whose children were diagnosed and are undergoing treatment for cancer. Methods: This qualitative study was conducted between June and November 2018. Data were gathered through semi-structured interviews held with 27 parents whose children were being treated for various cancers at the Paediatric Oncology Unit of the University of Port Harcourt Teaching Hospital, Nigeria. Results: Prior to diagnosis, knowledge of respondent about childhood cancers was deficient. Shock, disbelief and anxiety were often experienced when diagnosis was made known, while fear of the unknown and fear of death were significant concerns. Challenges at the workplace, especially lack of concentration and frequent absences were causes of added distress to mothers, while having a support group was a perceived need to help parents cope better. Positive behavioural changes in families were identified in the course of the child treatment. Conclusion: Parents caring for children with cancer face a wide range of distresses. There is need to empower healthcare providers as well as community members on ways to support these parents and help them cope with their child's illness and treatment. Original Research Article Eke; IRJO, 2(2): 1-8, 2019; Article no.IRJO. 49143 2
Surgical management of an accessory canal in a maxillary premolar: a case report

We report the surgical endodontic treatment of a maxillary first premolar with a lateral lesion that originated from an accessory canal. Although lesions originating from accessory canals frequently heal with simple conventional endodontic therapy, some lesions may need additional and different treatment. In the present case, conventional root canal retreatment led to incomplete healing with the need for further treatment (i.e., surgery). Surgical endodontic management with a fast-setting calcium silicate cement was performed on the accessory canal using a dental operating microscope. At the patient's 9-month recall visit, the lesion was resolved upon radiography.
Low FODMAP diet in children and adolescents with functional bowel disorder: A clinical case note review

Functional bowel disorders (FBD), such as irritable bowel syndrome (IBS), are increasingly more common in children and affect up to 20% of children. The etiology is multifactorial with no clear organic cause. Symptoms are recurrent and are associated with a reduced quality of life, school absences, and psychological challenges. Treatment options are variable. FODMAPs are short‐chained carbohydrates, poorly absorbed by the gastrointestinal tract due to their increased osmotic activity and excess gas production from the bacterial fermentation process. There is a paucity of data examining dietary interventions that restrict carbohydrates in children with IBS. The aim of this study was to examine the use of the low FODMAP diet (LFD) in children with an FBD.
The Contradiction of Obesity Incidence Based on Sleep Duration in Adolescents

Obesity is an abnormal state of excess body fat where obesity that occurs in adolescence increases the risk of obesity as an adult and causes several health problems. This study aims to differ the proportion of obesity incidence based on sleep duration in high school adolescents in the Tanah Abang District, Central Jakarta. The study design was cross sectional, sampling using the simple random sampling method, and a total sample of 100 students. Data analysis included univariate and bivariate analysis with chi-square tests. The results showed that respondents categorized as obese based on Body Mass Index (BMI) were 37 (37%) adolescents, and respondents categorized as obese was based on Body Fat Percent (PLT) of 32 (32%) adolescents. There is a difference in the proportion of obesity incidence based on sleep duration in adolescents (p value = 0.003, OR = 5.79). Adolescents should improve their sleep patterns according to the recommended duration to prevent obesity, which is at least 7 hours a day. ABSTRAK Obesitas merupakan keadaan kelebihan lemak tubuh yang abnormal dimana obesitas yang terjadi pada masa remaja meningkatkan risiko obesitas saat dewasa dan menimbulkan beberapa masalah kesehatan. Penelitian ini bertujuan perbedaan proporsi kejadian obesitas berdasarkan durasi tidur pada remaja SMA di Kecamatan Tanah Abang Jakarta Pusat. Desain penelitian adalah cross sectional, pengambilan sampel menggunakan metode simple random sampling, dan total sampel sebanyak 100 siswa. Analisis data meliputi analisis univariat dan bivariat menggunakan uji statistik chi-square. Hasil penelitian menunjukkan bahwa responden yang dikategorikan obesitas berdasarkan Indeks Massa Tubuh (IMT) sebanyak 37 (37%) remaja, dan responden yang dikategorikan obesitas berdasarkan Persen Lemak Tubuh (PLT) sebanyak 32 (32%) remaja. Ada perbedaan proporsi kejadian obesitas berdasarkan durasi tidur pada remaja (pvalue = 0,003, OR = 5,79). Sebaiknya remaja memperbaiki pola tidur sesuai dengan durasi yang dianjurkan agar mencegah terjadinya obesitas yaitu minimal 7 jam sehari.
Antibacterial Activity of Date Palm (PhoenixDectyliferaL.) Fruit at Different Ripening Stages

In vitro and in situ antibacterial activity of aqueous, ethanol, and ether extracts of three varieties of palm date (Khulase, Sheshi and Rezaz) in different maturation stages (Biser, Rutab and Tamer) were evaluated against some food borne pathogens. Gram positive bacteria showed higher sensitive against most extracts than Gram negative bacteria. Among the Gram positive bacteria, Listeria monocytogenesATCC 7644 and Staphylococcus saprophyticus ATCC 15305 recorded highest sensitive against most extracts. The ethanol followed by water extracts of Biser stage had a stronger antibacterial activity than other maturation stage for all varieties against Staphylococcus saprophyticus ATCC 15305. The results of Minimum Inhibitory Concentration (MIC) shows that Staphylococcus saprophyticus was very sensitive to the lowest concentration of ethanol extract of Rezaz variety at Biser stage (RBOH), (MIC, and 3.75 mg/ml). RBOH was able to reduce the count of Staphylococcus saprophyticus in minced meat by above of 1 log cycle during storage at 5°C. This extracts (RBOH) contained highest amount of phenolics (2035.3 mg/100g) compared to other extracts.
Performance of Health Care Workers towards Hepatitis C and B Patients

Background: Health care workers are a high risk group who are liable for acquiring infection of hepatitis B and C viruses and its transmission to their patients and close contacts. Aim: The aim of the present study was to identify performance of health care worker towards hepatitis B and C. Research Design: Cross-sectional descriptive study design was used. Sample & setting was consisted of 288 physician, nurse, and technician work directly with patients with HBV and HCV at four different settings which are affiliated to Main Mansoura University Hospitals (Specialized Medical Hospital, Gasteriology Center, Maternity and Gynecological Hospital, Egyptian Liver Research Institute and Hospital” in addition to elderly homes at Dakahlia Governorate). Tools: two tools were used to collect pertinent data which are structured questionnaire sheet and observational Checklist. Results: Results of current study revealed that study sample age ranged from 20 to 50 years with a mean age of 31.94 ± 7.40 years, regarding knowledge, physicians were more knowledgeable than other groups (nurses and technicians). The staff members who work at GIT center, Liver Research Institute and Hospital and Specialized Medical Hospital were more knowledgeable than staff members in other health care settings. 83.3% of health care workers had a positive attitude and more than half of them (58.3%) had a good practice. There was positive correlation between the knowledge, attitude and practice (p>0.05). Conclusion: The study revealed that, the physicians showed high level of performance regarding hepatitis B and C viruses’ infection compared with nurses and technicians. The study recommended that continuous in–service training program in safety measures is essential to all nurses and technicians to update their knowledge and improve their practice to care for patients with viral hepatitis.
Real-time Processing for Advanced Ultrasound Visualization

This thesis focuses on the development of visual computing techniques for advanced medical ultrasound visualization. At first, techniques for improved 2D B-mode ultrasound visualization are presented, where the observer is provided with real-time feedback on the uncertainty present in the image. The second part of this thesis then introduces an orientation-driven ultrasound compounding approach to create high-quality 3D ultrasound volumes. Finally, a novel predicate-based classification technique allows for more meaningful visualization of such data.
Investigating the Psychological Empowerment of Nurses in Educational Hospitals: A Study in Ahvaz Jundishapur University of Medical Sciences in Southwest Iran

Introduction: Medical education system has been integrated with the health and therapeutic services system in Iran, so investigating the empowerment status of nurses working in educational hospitals is an essential. This study was conducted for the same purpose. Materials and Methods: The population of this descriptive and cross-sectional study included all nurses working in educational hospitals of Ahvaz Jundishapur University of Medical Sciences in southwest of Iran. The questionnaires were distributed among all of them by census sampling method. Finally, 235 of them completed the questionnaires. To collect the data, the Spreitzer Empowerment Questionnaire was used. Descriptive and inferential statistics were used to analyze the data through SPSS 22 software. Results: Investigating the different components of nurses' empowerment revealed that the mean scores of the areas of impact (12.22 ± 2.15), meaning (11.48 ± 3.19), sense of competence (12.89 ± 2.50) and self-determination (12.87 ± 2.48) were at high level. In addition, variables such as employment history, education, age, type of employment and teaching hospital of nurses did not have a significant effect on their psychological empowerment (p>0.05). Discussion and Conclusion: In general, the psychological empowerment status of nurses in teaching hospitals of Ahvaz Jundishapur University of Medical Sciences was evaluated at high level. It is suggested that the managers of educational hospitals to provide the conditions so that the staff consider their work valuable and have an intrinsic interest in it. It could increase their active participation in solving the problems of health systems, medical treatment and education and make them to be an effective and creative member of the hospital.
Foreign Body Aspiration in Infants: Role of Self-Feeding.

Background: Foreign body aspiration (FBA) is a serious life-threatening condition in childhood. "Baby-led weaning (BLW)" is a popular method in which the babies are encouraged to self-feed to gain oral motor abilities. The role of BLW in FBA is controversial. A retrospective study was performed to evaluate the results of FBA in infants (<1 year of age) and its relation to the feeding method. Materials and Methods: Children who underwent bronchoscopy for FBA for the past 10 years were included. Infants (<1 year of age) were evaluated for age, gender, clinical findings, and the results of bronchoscopy. The type of feeding, including self-feeding or caregiver-assisted feeding, was noted. Results: The medical records of 826 patients who underwent bronchoscopy were evaluated. FBA was noted in 50.2% (n = 417) of cases. Only 9.07% (n = 75) of patients were <1 year of age and 67% (n = 50) of them had a foreign body according to the bronchoscopy. The mean age was 9 months (5-12 months) and 36% of them were male. When the feeding characteristics of patients were surveyed, 80% of cases aspirated when self-feeding and 14% aspirated during caregiver-assisted feeding. Conclusions: Self-feeding to promote oral motor function may cause FBA in infants. Emergent bronchoscopy is more common in infants and reveals the aspiration of foods that cannot be consumed safely in this age group.