Miracle-dz/UniFAR-FTUs huggingface dataset:
Osteoid osteoma: resection with CT guidance.

BACKGROUND Osteoid osteoma is a benign bone lesion characterized by nocturnal pain mostly, which may be relieved by non-steroidal prostaglandin inhibitors. Treatment by complete resection of the nidus immediately relieves the pain. Intraoperative location of the nidus may be difficult, and extensive bone resection may be necessary to ensure complete excision. Few studies have described resection of osteoid osteoma under CT guidance, and little attention has been given to lesions near the neurovascular bundle. OBJECTIVE To report our results of osteoid osteoma resection under CT guidance, with specific attention to lesions lying near the neural structure. METHODS Nine patients with suspected osteoid osteoma underwent resection with a 6.8 mm core drill under CT guidance. RESULTS Histologic confirmation was obtained in seven patients, while in two there was no evidence of the nidus in the excised bone material. All nine reported complete pain relief immediately after the surgery. Postoperative CT scan showed complete removal of the osteoid osteoma. CONCLUSIONS Removal of osteoid osteoma under CT guidance is simple, safe and allows complete removal of the nidus with low morbidity.
Career Stage and Organizational Citizenship Behaviour among Indian Managers

Organizational citizenship behavior is now considered as fifth bottom line variable in organization behavior research and practice. Several studies have been conducted to identify antecedents and consequences of this bottom line variable. By using the career stage model proposed by Super, we have endeavored to identify the levels of organizational citizenship behavior in different career stages. The research was conducted on 210 front level Indian managers. The results reveal that the executives exhibited significantly high level of OCB in establishment and maintenance stage than trial stage of the career. Although, differences of means score of OCB, in establishment and maintenance stage was trivial.
Policing immigrant communities in the United States

Purpose – This chapter examines some of the dilemmas involved in policing immigrant communities. Methodology – The chapter is based upon the relatively limited research literature on policing immigrant communities, an ongoing review of the contemporary dynamics of this issue in cities and states using the Internet, and original research in Chicago where a large and rapidly growing immigrant Latino community offers examples of most of the observations made by others. Findings – The chapter first examines some of the barriers limiting the ability of local police to work effectively in heavily immigrant areas. It then describes how these barriers are exacerbated by the presumed presence of significant concentrations of unauthorized migrants as well as legal residents. Demands that local police in the United States become more involved in enforcing immigration laws have become a point of great contention because this involvement runs at cross-purposes with community policing and other strategies to engage more closely with the community. Research implications – The magnitude of this conflict is illustrated by current debate over “sanctuary cities. ” These are communities where local officials have resisted the enforcement priorities of the federal government, and have continued to emphasize the role of the police in serving all residents.
Pessimistic, Anxious, and Depressive Personality Traits Predict All-Cause Mortality: The Mayo Clinic Cohort Study of Personality and Aging

Objective: To study the association between several personality traits and all-cause mortality. Methods: We established a historical cohort of 7216 subjects who completed the Minnesota Multiphasic Personality Inventory (MMPI) for research at the Mayo Clinic from 1962 to 1965, and who resided within a 120-mile radius centered in Rochester, MN. A total of 7080 subjects (98.1%) were followed over four decades either actively (via a direct or proxy telephone interview) or passively (via review of medical records or by obtaining their death certificates). We examined the association of pessimistic, anxious, and depressive personality traits (as measured using MMPI scales) with all-cause mortality. Results: A total of 4634 subjects (65.5%) died during follow-up. Pessimistic, anxious, and depressive personality traits were associated with increased all-cause mortality in both men and women. In addition, we observed a linear trend of increasing risk from the first to the fourth quartile for all three scales. Results were similar in additional analyses considering the personality scores as continuous variables, in analyses combining the three personality traits into a composite neuroticism score, and in several sets of sensitivity analyses. These associations remained significant even when personality was measured early in life (ages 20–39 years). Conclusions: Our findings suggest that personality traits related to neuroticism are associated with an increased risk of all-cause mortality even when they are measured early in life. CES-D = Center for Epidemiologic Studies—Depression; CI = confidence interval; EPI = Eysenck Personality Inventory; HADS = Hospital Anxiety and Depression Scale; HR = hazard ratio; IQR = interquartile range; MMPI = Minnesota Multiphasic Personality Inventory; NEO-FFI = NEO Five-Factor Inventory; NEO-PI-R = Revised NEO Personality Inventory; SD = standard deviation.
Ultra-short-term heart rate variability analysis on accelerometric signals from mobile phone

The feasibility of measuring stress-related parameters by ultra-short variability (USV) indices calculated from the ballistocardiographic signal acquired by the mobile phone accelerometers (m-BCG) positioned on the navel was tested, and its accuracy compared with gold standard ECG-derived indices. The m-BCG was acquired in six healthy volunteers while in supine position, during spontaneous breathing (CTRL) and during 1 minute of mental stress (MS) induced by arithmetic serial subtraction task. Beat occurrence was independently and automatically extracted from both ECG and m-BCG signals, to compute USV parameters in 30 s intervals, during both the CTRL and MS. Linear regression and Bland-Altman analyses between RR series and m-BCG derived beat-to-beat measurements (JJ series) showed very high correlation (r2>0.97), no bias, and narrow limits of agreement (±2SD < ±34 ms) for both CTRL and MS. A significant decrease (p=0.03 Wilcoxon test) in beat duration, SDNN and RMSSD was found in MS compared to CTRL, in both RR and JJ variability series, underlying the ability of m-BCG in capturing the decrease in parasympathetic tone in agreement with the induced stimulus.
Comparative Assessment of the Effects of Three Local Anesthetics: Lidocaine, Prilocaine, and Mepivacaine on Blood Pressure Changes in Patients with Controlled Hypertension.

BACKGROUND Given large number of patients with hypertension attending dental clinics and the profound effects of local anesthetics containing vasoconstrictors, this study aimed to compare the effects of lidocaine 2% + epinephrine, prilocaine 3% + felypressin0.03, and mepivacaine 3% on blood pressure changes. METHODS The current study was carried out from May 2014 to February 2015.Patients with controlled hypertension (systolic blood pressure<159.94 mmHg before the injection) who attended Zahedan dental school (Zahedan , Iran) for the extraction of a mandibular tooth were selected and randomly allocated to three groups of 20. Groups 1-3 received lidocaine 2% + epinephrine, prilocaine 3% + felypressin 0.03 units, and mepivacaine3%, respectively. Patients were only included if they were injected with a maximum of two 1.8 ml cartridges (3.6 ml) for tooth extraction (maximum epinephrine dose of 0.04 mg was maintained in systemic patients). The collected data were analyzed using the analysis of variance (ANOVA) in SPSS 19.0. (SPSS Inc., Chicago, IL, USA)RESULTS: No significant differences were observed between the systolic and diastolic blood pressure of the three groups. The three evaluated local anesthetic solutions had similar effects in patients with controlled hypertension. CONCLUSION While no significant changes in blood pressure were observed in three groups, all dental procedures on the mentioned group of patients have to be performed under careful monitoring and aspiration. Moreover, the maximum epinephrine dose (0.04mg) should never be exceeded in these patients.
Biomechanical walking pattern changes in the fit and healthy elderly.

A descriptive study of the biomechanical variables of the walking patterns of the fit and healthy elderly compared with those of young adults revealed several significant differences. The walking patterns of 15 elderly subjects, selected for their active life style and screened for any gait- or balance-related pathological conditions, were analyzed. Kinematic and kinetic data for a minimum of 10 repeat walking trials were collected using a video digitizing system and a force platform. Basic kinematic analyses and an inverse dynamics model yielded data based on the following variables: temporal and cadence measures, heal and toe trajectories, joint kinematics, joint moments of force, and joint mechanical power generation and absorption. Significant differences between these elderly subjects and a database of young adults revealed the following: the same cadence but a shorter step length, an increased double-support stance period, decreased push-off power, a more flat-footed landing, and a reduction in their "index of dynamic balance. " All of these differences, except reduction in index of dynamic balance, indicate adaptation by the elderly toward a safer, more stable gait pattern. The reduction in index of dynamic balance suggests deterioration in the efficiency of the balance control system during gait. Because of these significant differences attributable to age alone, it is apparent that a separate gait database is needed in order to pinpoint falling disorders of the elderly.
Analyzing EEG signals under insulin-induced hypoglycemia in type 1 diabetes patients

Hypoglycemia is dangerous and considered as a limiting factor of the glycemic control therapy for patients with type 1 diabetes mellitus (T1DM). Nocturnal hypoglycemia is especially feared because early warning symptoms are unclear during sleep so an episode of hypoglycemia may lead to a fatal effect on patients. The main objective of this paper is to explore the correlation between hypoglycemia and electroencephalography (EEG) signals. To do this, the EEG of five T1DM adolescents from an overnight insulin-induced study is analyzed by spectral analysis to extract four different parameters. We aim to explore the response of these parameters during the clamp study which includes three main phases of normal, hypoglycemia and recovery. We also look at data at the blood glucose level (BGL) of 3.3-3.9 mmol/l to find a threshold to distinguish between non-hypoglycemia and hypoglycemia states. The results show that extracted EEG parameters are highly correlated with patients' conditions during the study. It is also shown that at the BGL of 3.3 mmol/l, responses to hypoglycemia in EEG signals start to significantly occur.
Assessment of the Pharmacogenomics Educational Needs of Pharmacists

Objectives. To evaluate the self-perceived knowledge and confidence of inpatient and outpatient pharmacists in applying pharmacogenomics information to clinical practice. Methods. A 19-question multiple-choice, electronic needs-assessment survey instrument was distributed to 480 inpatient and outpatient pharmacists in a large, academic, multi-campus healthcare system. Results. The survey response rate was 64% (303). Most respondents (85%) agreed that pharmacists should be required to be knowledgeable about pharmacogenomics, and 65% agreed that pharmacists should be capable of providing information on the appropriate use of pharmacogenomics testing. Sixty-three percent felt they could not accurately apply the results of pharmacogenomics tests to drug-therapy selection, dosing, or monitoring. Conclusion. Pharmacists believe pharmacogenomics knowledge is important to the profession, but they lack the knowledge and self-confidence to act on the results of pharmacogenomics testing and may benefit from pharmacogenomics education.
Exploration intensity, analysts’ private information development and their forecast performance

This study examines whether analysts in the extractive industries in Australia adjust their private information searching and processing in response to the complexity of information about a firm’s exploration and evaluation (E&E) activities. We find that both the proportion of private information in their forecasts and the accuracy of their forecasts increase with the intensity of E&E activities. Additional analyses reveal that this effect is more pronounced for firms with substantial E&E activities but limited production activities, and that analysts’ private information development activities are mainly related to the capitalized E&E expenditures. Our results provide guidance for both investors and future standard setters. They show that investors can benefit from analysts’ expertise in situations of high information asymmetry. They also provide evidence of the advantage of distinguishing successful from unsuccessful investments in resource exploration when accounting for E&E expenditures, which may inform future decisions about accounting for intangible assets.
Antiplatelet Treatment Reduces All-Cause Mortality in COPD Patients: A Systematic Review and Meta-Analysis

ABSTRACT Previous studies clearly showed that patients with chronic obstructive pulmonary disease (COPD) are at high risk for cardiovascular events. Platelet activation is significantly heightened in these patients, probably because of a chronic inflammatory status. Nevertheless, it is unclear whether antiplatelet treatment may contribute to reduce all-cause mortality in COPD patients. To clarify this issue, we performed a systematic review and meta-analysis including patients with COPD (outpatients or admitted to hospital for acute exacerbation). The primary endpoint was all-cause mortality. We considered studies stratifying the study population according the administration or not of antiplatelet therapy and reporting its relationship with the primary endpoint. Overall, 5 studies including 11117 COPD patients were considered (of those 3069 patients were with acute exacerbation of COPD). IHD was present in 33% of COPD patients [95%CI 31%–35%). Antiplatelet therapy administration was common (47%, 95%CI 46%–48%), ranging from 26% to 61%. Of note, IHD was considered as confounding factor at multivariable analysis in all studies. All-cause mortality was significantly lower in COPD patients receiving antiplatelet treatment (OR 0.81; 95%CI 0.75–0.88). The data was consistent both in outpatients and in those with acute exacerbation of COPD. The pooled studies analysis showed a very low heterogeneity (I2 : 8%). Additional analyses (meta-regression) showed that antiplatelet therapy administration was effective independently (to potential confounding factors as IHD, cardiovascular drugs and cardiovascular risk factors. In conclusion, our meta-analysis suggested that antiplatelet therapy might significantly contribute to reduce all-cause mortality in COPD patients.
A case-control study of asthma among U.S. Army Gulf War veterans and modeled exposure to oil well fire smoke.

OBJECTIVE Thousands of American troops were exposed to oil well fire smoke during the Persian Gulf War, but the actual impact of this on their health is unknown. To assess the potential association between physician-diagnosed asthma and objective estimates of oil fire smoke, we conducted a case-control study of Army Gulf War veterans. METHODS Subjects were participants in the Comprehensive Clinical Evaluation Program. Cases had physician-diagnosed asthma; controls were selected from the population of noncases. The two estimates of exposure were cumulative exposure and number of days at high levels. RESULTS A total of 873 cases and 2,464 controls were included. Significant associations were observed between asthma and both estimates of exposure, with an adjusted odds ratio of 1.4 (95% confidence interval = 1.11.8) for both the highest levels of cumulative exposure and days exposed to high levels. A dose response was observed for both exposure measures. CONCLUSIONS We found significant associations between asthma and oil fire smoke exposure. Because much of the medical history was not available, an etiological association cannot be determined from this study, and additional research is needed.
Estimating risks in declining populations with poor data

Census data on endangered species are often sparse, error-ridden, and confined to only a segment of the population. Estimating trends and extinction risks using this type of data presents numerous difficulties. In particular, the estimate of the variation in year-to-year transitions in population size (the “process error” caused by stochasticity in survivorship and fecundities) is confounded by the addition of high sampling error variation. In addition, the year-to-year variability in the segment of the population that is sampled may be quite different from the population variability that one is trying to estimate. The combined effect of severe sampling error and age- or stage-specific counts leads to severe biases in estimates of population-level parameters. I present an estimation method that circumvents the problem of age- or stage-specific counts and is markedly robust to severe sampling error. This method allows the estimation of environmental variation and population trends for extinction-risk analyses using corrupted census counts—a common type of data for endangered species that has hitherto been relatively unusable for these analyses.
The passive diffusion of Leptospira interrogans

Motivated by recent experimental measurements, the passive diffusion of the bacterium Leptospira interrogans is investigated theoretically. By approximating the cell shape as a straight helix and using the slender-body-theory approximation of Stokesian hydrodynamics, the resistance matrix of Leptospira is first determined numerically. The passive diffusion of the helical cell is then obtained computationally using a Langevin formulation which is sampled in time in a manner consistent with the experimental procedure. Our results are in excellent quantitative agreement with the experimental results with no adjustable parameters.
Use of force-plate analysis of gait to compare two surgical techniques for treatment of cranial cruciate ligament rupture in dogs.

OBJECTIVE To use ground reaction forces and related impulses as an objective measurement of limb function in the comparison of 1 extracapsular and 1 intracapsular surgical technique for repair of cranial cruciate ligament rupture in dogs. ANIMALS 18 healthy dogs. DESIGN All dogs underwent force-plate analysis of gait prior to transection of the left cranial cruciate ligament. The dogs were randomly allotted to 3 groups. The ligamentous instability was corrected, using a modified retinacular imbrication technique (MRIT) in 1 group and an under-and-over technique in another group. No attempt was made to correct the ligamentous instability in a control group. Clinical grading of lameness and force-plate analysis of gait were performed at 4, 8, 12, 16, and 20 weeks after surgery. PROCEDURE Peak vertical force and vertical, braking, and propulsion impulses were recorded for each limb at each time. The degree of clinical lameness was graded at each time. RESULTS Left hind limb peak vertical forces and vertical impulses were significantly decreased at all times after surgery in the control and under-and-over technique group, compared with values before surgery. Dogs of the MRIT group had improved by 20 weeks, with no significant differences between left hind limb peak vertical forces or vertical impulses recorded before surgery and at 20 weeks. CONCLUSION Peak vertical forces and vertical impulses in dogs undergoing MRIT repair after experimentally created cranial cruciate ligament rupture are not significantly different when values recorded for the operated limb at 20 weeks after surgery are compared with those recorded prior to surgery.
SURFING INJURIES.

Skurfboarding is currently enjoying a phase of popularity, but it is not without hazards. Among 75 consecutive cases of skurfboard injuries seen in an emergency department, 29 fractures were encountered, 16 of which were in the region of the ankle and foot. The majority of injuries, however, consisted of sprains, contusions and abrasions. Six patients required hospital admission, three for operative management of fractures and three because of head injuries.The concrete playground, the instability of the board, the lack of protective clothing and the exhibitionist instincts of the teen-age enthusiast are suggested as factors responsible, at least in part, for the injuries sustained on skurfboards.
Toll-like receptor 4 expression during cerebral aneurysm formation. Laboratory investigation.

OBJECT The pathophysiological origin of cerebral aneurysms is closely associated with chronic inflammation in arterial walls. Recently, the authors identified nuclear factor-kappa B (NF-κB) as a key mediator of cerebral aneurysm formation and progression. Because Toll-like receptor 4 (TLR4) stimulates NF-κB activation in arterial walls in atherosclerosis, the authors hypothesize that TLR4 expresses in cerebral aneurysms and contributes to the activation of NF-κB in cerebral aneurysm walls. METHODS Cerebral aneurysms were induced in male Sprague-Dawley rats. Expression of TLRs in cerebral aneurysm walls was assessed using reverse transcriptase polymerase chain reaction (RT-PCR). The expression of TLR4 was examined using RT-PCR, immunohistochemical studies, and Western blotting. To assess TLR4 dependency on NF-κB activation, double immunostaining and a study using NF-κB-deficient mice were done. Finally, TLR4 expression in human cerebral aneurysm walls was assessed using immunohistochemical studies. RESULTS In cerebral aneurysm walls, TLR1, -4, -5, -6, -10, and -11 were expressed. Among them, TLR4 and TLR10 expression changed during cerebral aneurysm formation. Expression of TLR4 was predominantly in the endothelial cell layer of cerebral aneurysm walls, and was transitionally upregulated at the early stage of cerebral aneurysm formation. The TLR4 expression coincided well with NF-κB activation. In human cerebral aneurysms, TLR4 was also expressed in the endothelial cell layer, as it was in rats. CONCLUSIONS Toll-like receptor 4 was expressed in cerebral aneurysm walls both in rats and humans. This receptor may play a crucial role in cerebral aneurysm formation through NF-κB activation in endothelial cells. The results of the present study will shed new light on the pathogenesis of cerebral aneurysm formation.