Miracle-dz/UniFAR-FTUs huggingface dataset:
Regulation and the cost of equity capital in Australia

This paper examines four issues associated with the Officer model, in the context of estimating the cost of equity capital for regulatory purposes. The conclusions are thus. First, regarding the issue of foreign investors, continued use of a version of the Capital Asset Pricing Model that assumes that national share markets are segmented rather than integrated (such as the Officer model) is recommended. Second, a value for “gamma” of 1 rather than the generally employed figure of . 50 is recommended. Third, in respect of the market risk premium, continued use of the generally employed figure of 6% is recommended. Finally, regarding the differential taxation of capital gains and ordinary income, the simplifying assumption in the Officer model that they are equally taxed could lead to an error in estimating the cost of equity of up to 2% if individual firm values for the dividend yield are used, and up to 1.1% if industry average values are used. Whether this is a sufficiently large sum to warrant concern, and whether the ACCC should lead in this area, are arguable.
Parents' perceptions of the individualized family service plan

PARENTS’ PERCEPTIONS OF THE INDIVIDUALIZED FAMILY SERVICE PLAN MAY 2001 DESIREE P. LALBEHARIE-JOSIAS, B.A., SMITH COLLEGE M E D. , SMITH COLLEGE Ed.D. , UNIVERSITY OF MASSACHUSETTS AMHERST Directed by: Professor Patricia G. Silver The Individualized Family Service Plan (IFSP), is designed to offer a holistic family-centered approach to meet the needs of families with children with disabilities between the ages of 0 to 3 years old. The goal is to help support the family, and provide services that are specific to the child’s special needs in order to facilitate the child’s growth and development. Therefore, this is a very complex and comprehensive program that tries to help meet the needs of the child and family simultaneously. The goal of this study was to explore parents’ perceptions of the IFSP based on their experiences with the program. Twenty-one parents representing fourteen families of young children with disabilities, or experiencing developmental delays, who were either currently on, or have been part of an IFSP within the past 2 years, participated in this study. Qualitative research methods using a phenomenological design of in-depth interviews, together with follow-up interviews and a focus group were used in conducting this study. The results of this study revealed two categories of service coordination, and family experience and perspective, as the source of origination of themes and critical issues that the parents had highlighted. The themes included: the role of the caseworker; IFSP coordination;
Concerted functions of Streptococcus gordonii surface proteins PadA and Hsa mediate activation of human platelets and interactions with extracellular matrix

A range of Streptococcus bacteria are able to interact with blood platelets to form a thrombus (clot). Streptococcus gordonii is ubiquitous within the human oral cavity and amongst the common pathogens isolated from subjects with infective endocarditis. Two cell surface proteins, Hsa and Platelet adherence protein A (PadA), in S. gordonii mediate adherence and activation of platelets. In this study, we demonstrate that PadA binds activated platelets and that an NGR (Asparagine‐Glycine‐Arginine) motif within a 657 amino acid residue N‐terminal fragment of PadA is responsible for this, together with two other integrin‐like recognition motifs RGT and AGD. PadA also acts in concert with Hsa to mediate binding of S. gordonii to cellular fibronectin and vitronectin, and to promote formation of biofilms. Evidence is presented that PadA and Hsa are each reliant on the other's active presentation on the bacterial cell surface, suggesting cooperativity in functions impacting both colonization and pathogenesis.
Virtual Shopping: Breakthrough in Marketing Research

Publication languages: Data set: Elsevier Source The Journal of Product Innovation Management > 1996 > 13 > 6 > 558-559 Unfortunately, this is not a research report, but an advocacy presentation. A very good one, and full of details, but offering a marketing research method without a vigorous, balanced analysis of its strengths and weaknesses. This abstract will deal only with the portion of the article describing the method and how it can be used. Later authors will perhaps challenge the method as a new member of the research team.Under development for many years, virtual shopping is the consequence of research on in-store presentations and sales forecast modeling. The centerpiece is a computer screen, on which is projected a simulated purchasing environment. Usually an in-store array of shelves and products, it emulates the actual simulated stores used for years in shopping mall spaces. As consumers scan through the store, they see various product categories, with a selection of various products in each category. They pick up a. more Identifiers journal ISSN : 0737-6782 Authors Additional information English Publisher Elsevier Science Fields of science No field of science has been suggested yet. article Read online Download Add to read later Add to collection Add to followed Share Export to bibliography Raymond R. Burke Virtual shopping: Breakthrough in marketing research Burke, Raymond (1996), "Virtual Shopping: Breakthrough in Marketing Research, Harvard Business Review, (March-April), 120-131. Comley, Pete, (1996), "The Use of the Internet as a Data Collection Method," at http://www.sga. co.uk/esomar.html. Coomber, R. (1997), "Using the Internet for Survey Research," Sociological Research Online, 2(2) at http://www.socresonline. org.uk/socresonline/2/2/2.html. Â Edmondson, Brad (1997), "The Wired Bunch: Online Surveys and Focus Groups Might Solve the Toughest Problems in Market Research. But Can the Internet Really Speak For Everyone? American Demographics, 19(June), 10-15. Eventually, a breakthrough of Virtual shopping was explored as it has been shammed and counterfeited by other marketers online. (Burke 1996). Â The technological advancements should offer new hope, opening opportunities in marketing research and beyond, with microchips making personal computing possible, this has thus far stimulated Virtual Shopping simulation for most companies. This has given managers an easy avenue to promoting products and promotions, packaging and merchandising at the same time. This has also been a tool to change the companies approach to a variety of strategic issues such as entering new markets and responding to new emerging competitors. Terms of service Accessibility options Report an error / abuse © 2015 Interdisciplinary Centre for Mathematical and Computational Modelling
JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1α–mediated glucose metabolism

Significance Cancer cells favor high rates of aerobic glycolysis, or the Warburg effect, which is mediated by a key molecule, pyruvate kinase muscle isozyme (PKM)2. PKM2 functions both as a cytosolic enzyme and a nuclear factor in tumor cells. This report shows that PKM2’s nuclear translocation is regulated by Jumonji C domain-containing dioxygenase (JMJD)5 via direct physical binding. JMJD5 hinders the PKM2 tetrameric assembly and facilitates PKM2’s nuclear translocation. Together, they modulate hypoxia-inducible factor 1α-mediated transcriptional reprogramming of metabolic genes. These results reveal a mechanism whereby PKM2’s activity can be modulated by a dioxygenase/demethylase. JMJD5, a Jumonji C domain-containing dioxygenase, is important for embryonic development and cancer growth. Here, we show that JMJD5 is up-regulated by hypoxia and is crucial for hypoxia-induced cell proliferation. JMJD5 interacts directly with pyruvate kinase muscle isozyme (PKM)2 to modulate metabolic flux in cancer cells. The JMJD5-PKM2 interaction resides at the intersubunit interface region of PKM2, which hinders PKM2 tetramerization and blocks pyruvate kinase activity. This interaction also influences translocation of PKM2 into the nucleus and promotes hypoxia-inducible factor (HIF)-1α–mediated transactivation. JMJD5 knockdown inhibits the transcription of the PKM2–HIF-1α target genes involved in glucose metabolism, resulting in a reduction of glucose uptake and lactate secretion in cancer cells. JMJD5, along with PKM2 and HIF-1α, is recruited to the hypoxia response element site in the lactate dehydrogenase A and PKM2 loci and mediates the recruitment of the latter two proteins. Our data uncover a mechanism whereby PKM2 can be regulated by factor-binding–induced homo/heterooligomeric restructuring, paving the way to cell metabolic reprogram.
The Mediating Effect of Relationship Quality on the Transaction Cost–Export Performance Link: Bangladeshi Exporters' Perspectives

This study explores how relationship quality might mediate the link between transaction cost variables and export performance. In the proposed conceptual model, relationship-specific assets and uncertainty affect export performance both directly and through relationship quality; survey data from 185 exporting organizations in Bangladesh provide the test of this model. This article thus proposes that transaction cost economics and relational exchange theories are complementary rather than competing theories. These conclusions arise because this study accounts for not only the direct effect of asset specificity and uncertainty on export performance but also their indirect effects through relationship quality, which have not been empirically tested or clarified previously.
Adoption of Soil Conservation Measures in Manilla Shire, New South Wales

Land in Manilla Shire, New South Wales, is characterised by serious soil erosion and land use is characterised by high rates of adoption of the recommended soil conservation measures. This behaviour is analysed to attempt to determine what factors are promoting soil conservation at each stage in the adoption process. The results suggest that policies to promote farmer perception of erosion problems should be formulated differently from those to promote actual adoption of the recommended measures. Perception of the problem depends mainly on the percentage of farm area that is eroded, but the likelihood of adoption depends mainly on the intensity of the erosion. The farmer's rating as an investor, the size and security of farm income, and the presence of institutional programmes are all significant factors which encourage adoption. While the stewardship motivation and personal factors encourage perception and recognition of a problem, economic factors promote actual adoption.
The influence of industry mix on regional new firm entry

Per capita rates of entry are commonly used to measure regional entrepreneurial climate. Yet entry rates vary widely by industry and tend to mirror existing regional specializations. Without controlling for industry mix, factors associated with regional differences in entry may describe the industry base rather than entrepreneurial climate. This study finds that while industry mix explains a potentially large portion regional variation in entry, it does not radically alter the relative standing of the most highly ranked regions. Most of the factors commonly associated with the regional entrepreneurial climate remain significant after purging the data of industry mix effects. However, a number of commonly-cited factors—namely, educational attainment, homeownership, University R&D, and unemployment—were found to be contingent upon industry structure. JEL classification: R11, M13, L26, O18
Syntactic Gender and Semantic Expectancy: ERPs Reveal Early Autonomy and Late Interaction

This experiment explored the effect of semantic expectancy on the processing of grammatical gender, and vice versa, in German using event-related-potentials (ERPs). Subjects were presented with correct sentences and sentences containing an article-noun gender agreement violation. The cloze probability of the nouns was either high or low. ERPs were measured on the nouns. The low-cloze nouns evoked a larger N400 than the high-cloze nouns. Gender violations elicited a left-anterior negativity (LAN, 300-600 msec) for all nouns. An additional P600 component was found only in high-cloze nouns. The N400 was independent of the gender mismatch variable; the LAN was independent of the semantic variable, whereas an interaction of the two variables was found in the P600. This finding indicates that syntactic and semantic processes are autonomous during an early processing stage, whereas these information types interact during a later processing phase.
Mobile lipids and metabolic heterogeneity of brain tumours as detectable by Ex Vivo 1H MR spectroscopy

To examine metabolic heterogeneity in primary brain tumour, multiple biopsies (one to five per tumour) from four benign meningiomas, five acoustic schwannomas, eleven glial tumours and five medulloblastomas were each subdivided into one to five samples (total = 194) and investigated using ex vivo 360 MHz 1H MR spectroscopy with histopathological correlation. Low amounts of mobile lipids were detected in meningothelial meningiomas and medulloblastomas, high amounts in some or all samples of all other tumours. The differences in non‐lipid metabolites between different tumour types were less marked, with the exception of the medulloblastomas, which had high amounts of N‐acetyl aspartate and cholines. The amount of mobile lipid correlated with Antoni type B areas in schwannomas and necrosis in a high grade giant cell tumour. The amount of lipid varied significantly from sample to sample in a grade 2 astrocytoma and grade 4 astrocytoma samples with 0–5% necrosis but did not correlate with the site in the tumour or histopathological characteristics. The metabolic heterogeneity occurred on a spatial scale at least as small as the size of the MR samples, i.e., ≤60 mg. These results suggest that the detection of metabolic heterogeneity and mobile lipids may have importance for the design of clinical studies.
Evidence on the Geographic Concentration of German Industries: Do High-Tech Clusters Really Matter?

The agglomeration of industries has received much interest both in empirical and theoretical work in recent time. Especially in Germany politicians became inspired by the notion of high-technology industry clusters and German regional policy has seen a wave of initiatives aiming at the formation of such clusters. This papers explorers in a systematic w ay the geographic concentration of German manufacturing industries and relates it to industry characteristics and agglomeration forces proposed by theory. The main finding is that there is no general relationship between agglomeration and R&D or high-technology related business which suggests that hope put in the fast and effective development of "high-tech" clusters might be disappointed.
Commentary - Invited Comment on "Opinion Leadership and Social Contagion in New Product Diffusion"

Iyengar, Van den Bulte, and Valente (2011; referred to as IVV in the rest of this paper) address a number of important questions in their paper, “Opinion Leadership and Social Contagion in New Product Diffusion. ” They have assembled a unique data set in which they are able to observe not only adoptions and network ties, but also marketing effort and two different potential measures of recipients’ leadership, one self-reported and the other sociometric. Their paper delivers a number of important and interesting results: (1) contagion exists even after controlling for many possible confounds including, most significantly, marketing efforts; (2) contagion is moderated by the recipients’ self-reported opinion leadership: opinion leaders are less responsive to the actions of others; (3) this is not true of sociometric leadership (indegree); (4) contagion is moderated by usage: adoption by a heavy user has a bigger impact on her ties’ decision to adopt; and (5) time of adoption is increasing in both indegree and self-reported leadership: influentials adopt earlier. Their paper promises to contribute to the evolving literature on word of mouth (WOM), and wordof-mouth marketing, in a number of ways. In this comment, I offer some opinions on where the paper stands in this literature and, perhaps more important and I hope more interesting, where the literature itself stands. The authors ground their inquiry in a set of three fundamental assumptions. I will discuss these assumptions that motivated their work and offer my perspective on IVV’s contribution to our ability to have faith in these assumptions. I will particularly highlight where I feel there may exist deeper, unanswered questions. I feel it important to stress that it is not my goal to write a review article on contagion or word of mouth. My goal is a simple one: to emphasize the contributions offered by IVV and to note the very real potential their paper offered to shift the focus of future researchers in the area. The authors argue that the field of word-of-mouth marketing is characterized by three assumptions. I address each of them in turn.
Stop Bashing: Chinese Firms Even Have Better Financial Reporting Quality

Starting in 2010, US regulators have taken a series of actions in response to the accounting fraud at some Chinese reverse merger companies (CRM) listed on the US capital markets. Recent studies have documented significant spillover or bashing effects against innocent Chinese firms but not against US reverse merger companies. There seems to be a perception that accounting fraud is widespread in Chinese firms. In this study we find that there are significant bashing effects against Chinese firms listed in China. We also find some evidence that the Chinese firms listed in China may even have better financial reporting quality than similar US firms. This study is important to academics, regulators and investors around the world.
The Effectiveness of a Cation Resin (Kayexalate) as an Adsorbent of Paraquat: Experimental and Clinical Studies

1 The cation-exchange-resin KayexalateR has an adsorption capacity for paraquat 15 times greater than activated charcoal and 6 times greater than Adsorbin. The oral LD 50 of paraquat in rats rose 2.1 times by intragastric injection of Kayexalate.1 2 In the present study, the survival rate of rats given Kayexalate or Adsorbin after paraquat administration was examined. Results of clinical studies on 22 patients are also presented.
Empirically supported treatments in pediatric psychology: bedtime refusal and night wakings in young children.

OBJECTIVE To review the literature for empirically supported treatments for bedtime refusal and night wakings in young children. METHODS An extensive review of the literature resulted in the inclusion of 41 studies that were evaluated according to the criteria established by the Task Force on Promotion and Dissemination of Psychological Procedures (1995). RESULTS Evidence exists indicating that extinction and parent education on the prevention of sleep problems can be considered well-established treatments. Furthermore, graduated extinction and scheduled awakenings are probably efficacious treatments, with positive routines a promising intervention. CONCLUSIONS A discussion of effectiveness, treatment feasibility, cost-effectiveness, and methodological limitations of the studies is provided. Recommendations for future directions for research in the treatment of these two common sleep disorders are presented.
Retail Experience Marketing : A study on customer perceptions of successful in-store experience marketing within retailing

It has been shown that in today’s society, businesses will need to consider not only selling products or services, but also experiences in order to fulfil customers’ increasing demand for more stimuli in purchase situations. Additionally, brick and mortar retailers will need to respond to the increased use of online sales channels through finding ways of attracting customers to their stores. One way of responding to both trends can be to practise Experience Marketing and thereby offer holistic, stimulating and memorable customer experiences at every purchase situation.With this insight, this thesis will investigate which specific factors that are perceived as important when creating successful in-store experiences. From this, the aim is to create a framework based on customers’ perceptions that can be useful for brick and mortar retailers when implementing experience marketing. Five propositions of what factors to include in order to create successful experiences are presented. These are tested and further developed through both quantitative and qualitative research. The empirical investigation results in the creation of a final suggested framework including the supported propositions, one new Additional Factor and several suggested subcategories within each factor. The final framework suggests following factors as important when creating successful experience marketing: Store Environment, Employee Characteristics, Senses and Additional Factor.
Expansion Financing and Capital Structure

We analyze the financing of an expansion project, as well as the pre-expansion capital structure decision. Using too much equity (debt) in the expansion financing results in under (over)-investment relative to the first-best (total firm value maximizing) policy. We identify the expansion financing packages that ensure first-best as well as second-best (optimal, or equity value maximizing) policies, and show that they are in general quite different. The optimal expansion financing package generally implies a significantly larger debt component than the first-best. With optimal expansion financing, the model's implications are consistent with empirical regularities such as (i) existing debt has a negative effect, while the debt component of expansion financing has a positive effect, on investment; (ii) the debt component of expansion financing is generally a decreasing function of the existing debt level, except for highly-levered firms; and (iii) the debt component of expansion financing is decreasing in growth opportunities. The ex-ante (pre-expansion) leverage ratio is also identified for both cases - first-best and second-best expansion financing. In the latter case, the model's implications are again consistent with empirical regularities: (i) growth opportunities have a negative effect on both book and market optimal leverage ratios; and (ii) optimal leverage ratio is negatively related to earnings or profitability. Overall, the available empirical evidence suggests that expansion decisions are usually second-best, i.e., made to maximize equity value rather than total firm value.
Femtosecond laser-assisted corneal surgery

Purpose of review The femtosecond laser has potentially improved the safety and precision of creating corneal flaps in laser in situ keratomileusis (LASIK). This review focuses on recent advances in applying femtosecond laser technology to other corneal procedures. Recent findings The femtosecond laser is capable of cutting tissue at various depths and patterns with minimal collateral tissue injury. The laser can now be used to perform corneal pockets for ring segments, arcuate wedge-shaped resection in correction of high astigmatism, lamellar dissections in anterior lamellar keratoplasty, donor tissue preparation in Descemet's stripping endothelial keratoplasty, and shaped full-thickness keratoplasty. Summary Femtosecond laser-assisted corneal surgery may provide a more precise and safer approach to corneal surgery.