Miracle-dz/UniFAR-FTUs huggingface dataset:
Factors affecting days open, gestation length, and calving interval in Florida dairy cattle.

Effects of several factors on reproductive performance were evaluated. Mean performance and number of observations were for days from parturition to first service, 93 and 7730; days from first to successful service, 35 and 11,751; days open, 123 and 8571; gestation length, 280 and 13,612; and calving interval, 400 and 8524. Data covered 52 yr during which no detectable trends in calving interval occurred; other variables changed slightly. Jerseys had 8 fewer d from parturition to first service, 16 fewer d from first service to conception, 8 fewer d open, and 8-d shorter calving intervals than did Guernseys and Holsteins, which did not differ. Cows freshening in warm rather than cool weather suffered by 7, 7, 12, and 13 d for these variables. Repeatabilities ranged from . 05 to . 12; heritabilities were . 05 and . 06. Nonmaternal estimate of heritability of gestation length was . 22. Phenotypic and genetic correlations between days from parturition to first service and calving interval were . 48 and . 87; for days open and calving interval, they were . 97 and . 96. Although days from first to successful service were essentially uncorrelated with days open and calving interval phenotypically (.05), genetic correlations were greater than 1.0 and estimated as unity. Results show no discrepancy between estimates for measures of reproductive performance in a subtropical environment and numerous studies in temperate areas. Large studies from subtropical areas are sparse; essentially none concerns long-term trends.
External quality assessment program for detection of glucose-6-phosphate dehydrogenase deficiency in the Guangxi region

The aim of this study is to improve the quality of testing for glucose-6-phosphate dehydrogenase (G6PD) deficiency through evaluation and analysis of the laboratory tests for G6PD activity. External quality assessment (EQA) was carried out twice per year with five samples each from 2014 to 2016. Samples were used for quantitative and qualitative assays. Quantitative results were collected, qualitative results were determined with reference values, and information about methods, reagents and instruments from participating laboratories within the required time. Laboratory performance scores, coefficient of variation (CV), and the rates of false negative and positive results were calculated. As a result, a total of 2,834 cases of negative quality control (QC) samples and 2,451 cases of positive QC samples were assessed, where the rates of false negative and false positive results were 1.31% (37/2,834) and 1.34% (33/2,451), respectively. Quantitative results indicated an increasing trend in testing quality, which were consistent with conclusions based on the comparison of EQA full-score and acceptable ratio in six assessments. The 2nd assay in 2016 had the best full-score ratio of 68.9% (135/196) and best acceptable ratio of 84.2% (165/196). There was a decreasing trend in the average CV of six reagents produced in China, and the range of average CV increased to 14.6–23.6% in 2016. The average CV of low level and high level samples was 22.5% and 15.3%, respectively, demonstrating that samples with low G6PD activity have greater interlaboratory CV values. In conclusion, laboratories improved their testing quality and provided better diagnostic service for G6PD deficiency in areas with high incidence after participation in the EQA program in the Guangxi region.
The effect of combined inositol hexakisphosphate and inositol supplement in streptozotocin‐induced type 2 diabetic rats

Inositol hexakisphosphate (IP6) and inositol both regulate insulin secretion, but their combined use in the management of diabetes deserves investigation. The combined effects of IP6 and inositol supplementation were investigated in streptozotocin‐induced type 2 diabetic rats. The following groups of rats were studied for 8 weeks: non‐diabetic control, non‐diabetic high‐fat diet control, diabetic untreated, diabetic rats treated with the combination of IP6 and inositol (650 mg/kg bw) and diabetic rats treated with glibenclamide (10 mg/kg bw). High‐fat diet and streptozotocin were used to induce type 2 diabetes mellitus in Sprague–Dawley rats. Body weight, blood glucose, glycated haemoglobin, insulin, serum leptin, HOMA‐insulin resistance scores, intestinal amylase activity, serum and faecal lipids and food and fluid consumption were measured. Treatment with the combination significantly reduced blood glucose (306 ± 53 mg/dl) and insulin resistance score (1.93 ± 0.45) compared with diabetic controls (522 ± 24 mg/dl and 5.1 ± 0.69 respectively). Serum leptin (2.8 ± 0.6 ng/dl) and faecal triglycerides (108 ± 8 mg/dl) were significantly increased in rats treated with the combination compared with the diabetic control (1.8 ± 0.06 ng/dl and 86 ± 4 mg/dl). Serum triglyceride (47 ± 5.1 mg/dl), total cholesterol (98 ± 3.2 mg/dl) and food intake (26 ± 0.3 g) were significantly reduced by 45%, 25% and 25%, respectively, in rats treated with the combination compared with the diabetic control. Inositol and IP6 combined supplementation may be effective in the management of type 2 diabetes mellitus and related metabolic disorders by regulating some aspects of lipid and carbohydrate metabolism.
Plasma Vasopressin and V2 Receptor in the Endolymphatic Sac in Patients With Delayed Endolymphatic Hydrops

Objective: There are some kinds of sicknesses provoked by inadequate adaptation to physical and/or psychogenic stress in daily life. Delayed endolymphatic hydrops (DEH) is an inner ear disease like Ménière's disease (MD) characterized by episodic vertigo in the setting of preexisting unilateral deafness that especially occurs in civilized people with a stressful lifestyle. Its otopathologic finding was demonstrated to be inner ear endolymphatic hydrops through a temporal bone study in 1976, as in the case with MD in 1938. To elucidate the relationship between stress and the inner ear, we examined the plasma antidiuretic stress hormone vasopressin (pAVP) and its type 2 receptor (V2R) expression in the endolymphatic sac in patients with DEH. Study Design: A prospective molecular biological study. Methods: Between 1998 and 2007, we enrolled 20 patients with ipsilateral DEH to examine their pAVP during remission from vertigo attacks. Plasma vasopressin was also examined in 87 patients with unilateral MD and 30 control patients with chronic otitis media. Using the real-time polymerase chain reaction method with tissue samples obtained during surgery, we examined V2R mRNA expression in the endolymphatic sac in 6 patients with ipsilateral DEH, 9 patients with unilateral MD, and 6 control patients with acoustic neuroma. Results: Plasma vasopressin (1.5 times versus controls; unpaired t test, p = 0.140) and V2R mRNA expression in the endolymphatic sac (35.8 times versus controls; unpaired t test, p = 0.002) were higher in patients with DEH compared with those with acoustic neuroma. There were no significant differences in pAVP or V2R expression in the endolymphatic sac between DEH and MD. Patients with DEH showed a significantly negative correlation between pAVP and V2R (Pearson test, r = −0.92, p = 0.009) as in those with MD (Pearson test, r = −0.68, p = 0.043). Conclusion: Civilized people are frequently exposed to stress in their daily life, and pAVP can easily become elevated at any time. Therefore, a negative feedback system between pAVP and V2R in the endolymphatic sac may function for inner ear fluid homeostasis against stress-induced increases in pAVP. For the pathogenesis of endolymphatic hydrops resulting in vertigo attacks in patients with DEH as well as MD, pAVP may represent a matter of consequence, but V2R overexpression in the endolymphatic sac could be much more essential as a basis for these diseases.
African-American, Anglo-American, and Anglo-Canadian Grade 4 Children's Concepts of Old People and of Extended Family

A cross-national study of 104 fourth grade children's concepts of old people and extended family was conducted in Canada and the United States, using the Children's Attitudes Toward the Elderly Scale (CATE), and a modified version of the Gilby and Pederson (1982) Family Concept Interview. Both Anglo-American and African-American children were included in the U.S. sample. Results indicated that Anglo-American and Anglo-Canadian children were significantly more similar in their attitudes toward the elderly and their concepts of family than African-American and Anglo-American children. In comparison with the other two cultural groups, Anglo-American children were significantly more likely to include extended family members in their concept of who is family; Anglo-Canadian children had a significantly higher level of age discrimination ability; and African-American children showed a trend toward more positive attitudes toward older people. Overall findings of negative attitudes toward old people were consistent with earlier studies. The implications of children's ageist attitudes for increasingly aging Western societies are noted, particularly given impoverished children's potential need for extrafamilial social supports.
Nutritional energetics in fish: energy and protein utilization in rainbow trout (Salmo gairdneri).

Article de synthese sur la bioenergetique chez le poisson, etude des particularites chez la truite. Apport energetique des aliments; Methode de mesure de la digestibilite, coefficients de digestibilite apparente, energie digestible. Energie metabolisable. Retention d'energie nette. Equilibre energetique
Dosimetric comparison between IMRT delivery modes: Step-and-shoot, sliding window, and volumetric modulated arc therapy — for whole pelvis radiation therapy of intermediate-to-high risk prostate adenocarcinoma

This study was performed to evaluate dosimetric differences between current intensity modulated radiation therapy (IMRT) delivery modes: Step-and-shoot (SS), sliding window (SW), and volumetric modulated arc therapy (VMAT). Plans for 15 prostate cancer patients with 10 MV photon beams using each IMRT mode were generated. Patients had three planning target volumes (PTVs) including prostate, prostate plus seminal vesicles, and pelvic lymphatics. Dose volume histograms (DVHs) of PTVs and organs at risk (OARs), tumor control probability (TCP) and normal tissue complication probabilities (NTCPs), conformation number, and monitor units (MUs) used were compared. Statistical analysis was performed using the analysis of variance (ANOVA) technique. The TCPs were < 99% with insignificant differences among modalities (P > 0.99). Doses to all critical structures were higher on average with SW method compared to SS, but insignificant. NTCP values were lowest for VMAT in all structures excepting bladder. Normal tissue volumes receiving doses in the 20-30 Gy range were reduced for VMAT compared to SS. Percentage of MUs required for VMAT to deliver a comparable plan to SS and SW was at least 40% less. In conclusion, similar target coverage and normal tissue doses were found by the three compared modes and the dosimetric differences were small.
EFFECTS OF DIRECT HAEMOPERFUSION THROUGH FIBRES IMMOBILIZING POLYMYXIN B AND NAFAMOSTAT MESILATE ON ENDOTOXAEMIA IN CONSCIOUS GUINEA‐PIGS

1 Direct haemoperfusion through a network of fibres immobilizing polymyxin B (PMX‐B) is used for the treatment of septic shock, but the mechanism underlying its clinical benefits remains unclear. The aims of the present study were to assess the actions of direct haemoperfusion through fibres immobilizing PMX‐B (PMX‐DHP) on the effects of exogenously administered endotoxin in conscious guinea‐pigs and to examine the difference in the effects of heparin compared with nafamostat mesilate (NM) used as an anticoagulant. Although nafamostat is widely used in Japan, the agent cannot necessarily be used elsewhere in the world. Therefore, the study aimed to investigate and elucidate the effectiveness of NM compared with heparin. 2 Colonic motion was monitored continuously via telemetry using a force transducer attached to the taenia caecum, whereas blood pressure was monitored using a carotid artery catheter. To establish a haemoperfusion circuit in each freely moving and conscious guinea‐pig, catheters were implanted in the carotid artery and the jugular vein, tunnelled subcutaneously, exteriorized at the back of the neck in contact with a lightweight tethering spring and attached to a swivel device at the top of the cage. On the day after the operation, lipopolysaccharide (LPS; Escherichia coli, O111:B4; 1 mg/kg) was administered i.v. and PMX‐DHP was conducted for 2 h. Heparin (50 IU/h) or NM (0.4 mg/h) was used as the anticoagulant. Furthermore, guinea‐pigs were administered a lethal dose of LPS (10 mg/kg) and the survival rate was examined for animals undergoing PMX‐DHP compared with control animals. 3 In guinea‐pigs treated with PMX‐DHP, relaxation of colonic longitudinal muscle caused by LPS was significantly suppressed, as were decreases in blood pressure. Of the two anticoagulants used, NM was more effective than heparin. In addition, PMX‐DHP significantly increased the survival rate of guinea‐pigs that received potentially lethal doses of LPS. 4 In ca onscious and unrestrained guinea‐pig endotoxaemia model, PMX‐DHP significantly improved intestinal paralysis and decreases in blood pressure. These effects were augmented more by NM than by heparin when an anticoagulant was used in the perfusion process. These findings suggest that haemoperfusion using PMX and NM performed in the early stage of endotoxaemia is an effective treatment.
Amygdala interconnections with the cingulate motor cortex in the rhesus monkey

Amygdala interconnections with the cingulate motor cortices were investigated in the rhesus monkey. Using multiple tracing approaches, we found a robust projection from the lateral basal nucleus of the amygdala to Layers II, IIIa, and V of the rostral cingulate motor cortex (M3). A smaller source of amygdala input arose from the accessory basal, cortical, and lateral nuclei, which targeted only the rostral region of M3. We also found a light projection from the lateral basal nucleus to the same layers of the caudal cingulate motor cortex (M4). Experiments examining this projection to cingulate somatotopy using combined neural tracing strategies and stereology to estimate the total number of terminal‐like immunoreactive particles demonstrated that the amygdala projection terminates heavily in the face representation of M3 and moderately in its arm representation. Fewer terminal profiles were found in the leg representation of M3 and the face, arm, and leg representations of M4. Anterograde tracers placed directly into M3 and M4 revealed the amygdala connection to be reciprocal and documented corticofugal projections to the facial nucleus, surrounding pontine reticular formation, and spinal cord. Clinically, such pathways would be in a position to contribute to mediating movements in the face, neck, and upper extremity accompanying medial temporal lobe seizures that have historically characterized this syndrome. Alterations within or disruption of the amygdalo‐cingulate projection to the rostral part of M3 may also have an adverse effect on facial expression in patients presenting with neurological or neuropsychiatric abnormalities of medial temporal lobe involvement. Finally, the prominent amygdala projection to the face region of M3 may significantly influence the outcome of higher‐order facial expressions associated with social communication and emotional constructs such as fear, anger, happiness, and sadness. J. Comp. Neurol. 500:134–165, 2007. © 2006 Wiley‐Liss, Inc.
Evaluation by indirect immunofluorescent assay and enzyme linked immunosorbent assay of the dynamic changes of serum antibody responses against severe acute respiratory syndrome coronavirus.

BACKGROUND Severe acute respiratory syndrome coronavirus (SARS-CoV) is a newly emerging virus that gives rise to SARS patients with high rates of infectivity and fatality. To study the humoral immune responses to SARS-CoV, the authors evaluated IgG and IgM specific antibodies in patients' sera. METHODS Two methods, enzyme-linked immunosorbent assay (ELISA) and indirect immunofluorescent assay (IFA), were used to detect specific serum IgG and IgM against SARS-CoV in 98 SARS patients and 250 controls consisting of patients with pneumonia, health-care professionals and healthy subjects. The serum antibody profiles were investigated at different times over one and a half years in 18 of the SARS patients. RESULTS The sensitivity and specificity of ELISA for detecting IgG against SARS-CoV were 100.0% and 97.2% and for IgM 89.8% and 97.6% respectively; the figures using IFA for IgG were 100.0% and 100.0% and for IgM 81.8% and 100.0% respectively. During the first seven days of the antibodies trace test, no IgG and IgM were detected, but on day 15, IgG response increased dramatically, reaching a peak on day 60, remaining high up to day 180 and decreasing gradually until day 540. On day 15, IgM was detected, rapidly reached a peak, then declined gradually until day 180 when IgM was undetectable. CONCLUSION The detection of antibodies against SARS virus is helpful in the clinical diagnosis of SARS.
Effects of maintenance of propofol-ketamine anesthesia with repeat bolus and constant rate infusion of propofol on physiological, biochemical, anesthetic and analgesic indices in dogs

The research work was aimed at investigating physiological, biochemical, analgesic and anesthetic indices of dogs anesthetized with propofol-ketamine and maintained with repeat bolus and constant infusions of propofol. Eight dogs, assigned to two groups (n=4), were used in this study. All dogs were pre-medicated with atropine (at 0.03 mg/kg bwt) and xylazine (at 2 mg/kg bwt). Anesthesia was induced by a concurrent administration of propofol (at 4 mg/kg bwt) and ketamine (at 2.5 mg/kg bwt). Maintenance of anesthesia in Group 1 was done with a repeat bolus of propofol (at 2 mg/kg bwt), while in Group 2 it was done with a constant infusion of propofol (at 0.2 mg/kg bwt/min). Gastrotomy was performed in both groups, and anesthesia was maintained for 60 min. Physiological, analgesic, anesthetic parameters and plasma glucose concentration were measured. There was no significant (P>0.05) difference found in the analgesia and pedal reflex scores, durations of analgesia and recumbency, recovery time and standing time between the groups. The heart rate, respiratory rate and rectal temperature reduced significantly (P
Traumatic brain injuries sustained in the Afghanistan and Iraq wars.

UNLABELLED Because these injuries can go unrecognized, nurses stateside need to know how to recognize possible cases and how to help. OVERVIEW When traumatic brain injury (TBI) occurs simultaneously with more obviously life-threatening wounds, it may go unrecognized. Civilians and military personnel working in or near combat zones are at risk for this injury. Blast-related and closed-head injuries, rather than penetrating injuries, constitute the majority of TBIs in this population. The authors describe the experiences of the Defense and Veterans Brain Injury Center team at Walter Reed Army Medical Center in Washington, DC, and present a composite case to illustrate the nurse's role in the assessment and care of the TBI patient.
Probabilistic learning of indexed families under monotonicity constraints: hierarchy results and complexity aspects

We are concerned with probabilistic identification of indexed families of uniformly recursive languages from positive data under monotonicity constraints. Thereby, we consider conservative, strong-monotonic and monotonic probabilistic learning of indexed families with respect to class comprising, class preserving and proper hypothesis spaces, and investigate the probabilistic hierarchies in these learning models. In the setting of learning indexed families, probabilistic learning under monotonicity constraints is more powerful than deterministic learning under monotonicity constraints, even if the probability is close to 1, provided the learning machines are restricted to proper or class preserving hypothesis spaces. In the class comprising case, each of the investigated probabilistic hierarchies has a threshold. In particular, we can show for class comprising conservative learning as well as for learning without additional constraints that probabilistic identification and team identification are equivalent. This yields discrete probabilistic hierarchies in these cases. In the second part of our work, we investigate the relation between probabilistic learning and oracle identification under monotonicity constraints. We deal with the question how much additional information provided by oracles is sufficient and necessary for compensating the additional power of probabilistic learning machines. In this context, we introduce a complexity measure in order to measure the additional power of the probabilistic machines in qualitative terms. One main result is that for each oracle A ≤T K, there exists an indexed family LA which is properly conservatively identifiable with p = 1/2, and which exactly reflects the Turing degree of A, i.e., LA is properly conservatively identifiable by an oracle machine M [B] iff A ≤T B. However, not every indexed family which is conservatively identifiable with probability p = 1/2 reflects the Turing degree of an oracle. Hence, the conservative probabilistic learning classes are higher structured than the Turing degrees below K. Finally, we prove that there exist learning problems which are conservatively (monotonically) identifiable with probability p = 1/2 (p = 2/3), but conservatively (monotonically) identifiable only by oracle machines having access to T OT . Dekan: Prof. Dr. Gerald Urban Vorsitzender der Prüfungskommission: Prof. Dr. Thomas Ottmann Erstreferent: Prof. Dr. Britta Schinzel Zweitreferent: Prof. Dr. Thomas Zeugmann (Uni Lübeck) Datum der Disputation: 31.Mai 2001
Disjunctures for Women and Frontline Workers: Implementation of the Family Violence Option

This research uses analysis of qualitative interviews with 10 battered welfare clients and 15 frontline welfare workers to examine the implementation of the Family Violence Option (FVO) under welfare reform. States adopting the FVO agree to screen for domestic violence, refer identified victims to community resources, and waive program requirements that would endanger the women or with which they are unable to comply. The analyses find that none of the 10 clients in this study received these services. This lack of services reflects four critical disjunctures between the formal policy and the policy experienced by the clients. It also reveals several more basic structural factors that provide conflicting mandates to frontline workers. Frontline workers’ discretionary behaviors enforce core rules related to welfare eligibility and reduce welfare caseloads but do not provide violence‐related services to victims.