Miracle-dz/UniFAR-FTUs huggingface dataset:
Convertible Call Protection and Capital Investment Timing

We appeal to the literature on optimal timing of capital investment to identify a metric that permits a new test of the sequential financing motive for financing with convertible securities. We argue that firms that should execute capital investment with little delay should design convertibles so that they may be called quickly. Using three different measures of the strength of call protection in an examination of over 900 convertibles issued during 1980 to 1998, we find unambiguous evidence in support of the hypothesized linkage. Thus Mayers' theoretical argument for the use of convertibles in staged investment is supported (D. Mayers, 1998, Why firms issue convertible bonds: The matching of financial and real investment options, Journal of Financial Economics).
Doing Well by doing good - or doing better by delegating?

Machiavelli advises against delegating the distribution of favors. We test this claim in an experiment, in which an investor can directly transfer money to a trustee or delegate this decision to another investor. Varying the value of the transfers of the investor and the delegate, we find that the trustee’s rewards follow a rather simple pattern. In all situations, both investors are rewarded, but the person who actually decides gets a higher reward. Delegation only pays off for the initial decision maker if the value of the delegate’s transfer is much higher than the value of the investor’s transfer.
The Basal Ganglia in Human Learning

For many years, the basal ganglia were described in anatomy courses as strictly motor structures. Certainly, some of the most obvious and debilitating symptoms shown by persons with basal ganglia disorders are problems in motor control. However, the basal ganglia are not limited to motoric aspects of behavior: recent research shows that they are involved in most areas of cognitive and emotional functioning, consistent with their anatomical connections with all areas of the cortex. This review will focus on the roles of the basal ganglia in human learning, particularly sequence learning and category learning. Current areas of research that are discussed include the differing roles of different basal ganglia regions, patterns of interaction between the cortex and basal ganglia, differences in positive and negative association learning, effects of dopaminergic medication on learning, whether basal ganglia–mediated learning is implicit or explicit, and how the basal ganglia learning systems interact with other learning systems, particularly within the medial temporal lobe.
Detection of Metastases from Gastrointestinal Neuroendocrine Tumors: Prospective Comparison of 18F-TOCA PET, Triple-Phase CT, and PET/CT

The purpose of the investigation was to assess positron emission tomography (PET), computed tomography (CT) and the image fusion of PET and CT (PET/CT) in the detection of metastases from gastrointestinal neuroendocrine tumors. In a prospective study, thirty-one patients were consecutively examined using a state-of-the-art PET/CT. PET was performed with a carbohydrated F-18-labeled somatostatin receptor ligand (Gluc-Lys([18F]FP-TOCA) from the base of the skull to the proximal thigh using a Pico-3D PET scanner. CT was performed with a noncontrast low-dose CT (LD-CT) and a venous-dominant contrast-enhanced CT (VD-CT) from the base of the skull to the proximal thigh and a hepatic arterial-dominant contrast-enhanced CT (AD-CT) from the epigastric region using a 16-slice CT. The data sets from PET and CT (LD-CT and VD-CT) were fused automatically. To assess a relative sensitivity of each imaging modality, the total number of metastases by summing the number of metastases depicted for each patient by the highest sensitive modality was used as reference standard. PET, LD-CT, AD-CT, VD-CT, PET/LD-CT and PET/VD-CT showed a lesion-by-lesion based overall detection rate for liver metastases (n=858) of 90.8% (P<0.001), 29.4% (P<0.001), 45.5% (P<0.001), 73.9% (P<0.001), 91.5% (P<0.001) and 100%. PET, LD-CT, VD-CT, PET/LD-CT and PET/VD-CT showed an overall detection rate for lymph node metastases (n=193) of 93.8% (P<0.001), 25.4% (P<0.001), 64.8% (P<0.001), 93.8% (P<0.001) and 100% and for osseous metastases (n=567) of 98.6% (P<0.005), 40.7% (P<0.001), 40.7% (P<0.001), 100% and 100%. Furthermore, PET revealed 2 (22.2%) of 9 intrapulmonal lesions seen on LD-CT, VD-CT, PET/LD-CT and PET/VD-CT. PET as single modality revealed most liver, lymph node and osseous metastases. The combination of molecular/metabolic with anatomical/morphological information improves the diagnostic accuracy for the detection of metastases in comparison to any single imaging modality. LD-CT cannot replace VD-CT in the detection of liver and lymph node metastases, but was equal in the detection of osseous metastases and identifying of pulmonary lesions.
The Effect of Job Security Regulations on Labor Market Flexibility: Evidence from the Colombian Labor Market Reform

Job security provisions are widely believed to reduce dismissals and hiring. In addition, in developing countries job security is believed to reduce compliance with labor regulations and to increase informal activity. Reductions in dismissal costs are, thus, often advocated as a way to increase labor market flexibility and to increase compliance with labor regulations. This paper analyzes the impact of a substantial reduction in dismissal costs introduced by the Colombian Labor Market Reform of 1990. A theoretical model illustrates the effect of dismissal costs when there is a noncompliant sector. The model shows the direct effect of a reduction in dismissal costs on increased turnover as well as the second order effects on wages and on the composition of the compliant and noncompliant sectors. Using microdata from the Colombian National Household Surveys, I exploit the temporal variability in dismissal costs together with the variability in coverage between formal and informal workers (who are not covered and were, thus, not directly affected by the reform). The differences-in-differences results indicate increased separations and accessions for formal workers relative to informal workers after the reform. Moreover, the increase in worker turnover was greatest among younger workers, more educated workers, and workers employed in larger firms who are most likely to have been affected by the reform. The estimates, together with the steady-state conditions of the model, suggest the reform contributed to 10% of the reduction in unemployment during the period of study.
ARIMBAY’S VERBAL LORE: AN ANTHOLOGY OF FOLKTALES

This is a descriptive ethno-literary research that documented, translated, classified, and analysed folktales from Barangay Arimbay, Legazpi City, Albay Province, Philippines. The ethnographic methods of data collection, as well as the vertical and horizontal tests of Manuel (1985) were employed in the validation of 74 diversified folktales gathered from the said locale. The Labovian and literary approaches for the structural and textual analysis were employed to identify structural patterns, themes, beliefs, values, cultural practices and traditions discernible from the texts. This study revealed that the environment plays a major influence in the creation, transmission and diffusion of varied types of folktales, while the life of a folktale largely depends upon its narrators and on its generational transmission. Said folktales mirror a belief system where the supernatural and paranormal outweigh religious influences. Arimbay folktales are well-springs of information about the people’s mythical, legendary, historical past and mainstream experiences which bridges
The Effect of Corporate Governance on Capital Structure in Public Listed Companies in Indonesia

This research examines the effect of corporate governance on capital structure decision in public listed companies in Indonesia. To describe corporate governance, the proxies used are the existence of independent commissioners in board of commissioner (BOC), audit committee possessing financial knowledge, audit committee's frequency of meeting, Big 4 auditors, ownership concentration, managerial ownership, and CEO tenure. The proxy for capital structure is debt ratio. This research utilizes Kompas 100 index as per August 2012 “ January 2013 as the base of the sample firms with exclusion of financial firms, banks, and insurance companies. Financial data will be collected from companies' annual report in the period 2007-2011. The method of analysis employed is multiple regression analysis. The data is subjected to multicollinearity test. The research finds that some variables of corporate governance do have relationship with capital structure. The presence of independent commissioner in BOC and the meeting frequency of audit committee are significantly negatively associated with debt ratio. Meanwhile, the presence of financial experts in audit committee is significantly positively associated with debt ratio. Other measures of corporate governance are not significant in their influence on debt ratio. The research concludes that some corporate governance factors do affect capital structure as the answer to the question whether corporate governance affects capital structure in Indonesian public listed companies or not. Interestingly, those significant corporate governance variables are all parts of BOC which is the most important element of corporate governance. Hence, BOC affects capital structure in Indonesian public listed companies. Keywords Capital Structure, Corporate Governance, Agency Theory, Debt Ratio, Indonesia
Mobile Learning Via SMS Among Distance Learners: Does Learning Transfer Occur?

The purpose of this study is to determine whether learners are willing to transfer learning in this mobile learning environment via SMS. The reason for this is to measure the effectiveness of the new method used in learning and education especially in distance education field. For this reason, studentsâ? responses are gathered which looked at three factors namely learner characteristic, learning design and learning environment. The data are gathered through a survey research design with questionnaires using five-point likert scale. The questionnaires was administered for 105 distance education students from four courses including Bachelor of Science, Bachelor of Arts, Bachelor of Social Science and Bachelor of Management. The Rasch Model Analysis was used to measure these dimensions. Rasch Model is a one-parameter logistic model within item response theory (IRT) whereby the amount of a given latent trait in a person and the amount of that same latent trait reflected in various items can be estimated independently yet still compared explicitly to one another. The result of the study showed that learning transfer occurred and being influenced most by learnerâ? s characteristics especially in term of their motivation as well as their perceive utility/value of the SMS learning to their job and academic performances.
Initial Public Offerings in Canada: A Test of the Underpricing Theories and Aftermarket Performance

The under-pricing and the long-run performance of initial public offerings (IPOs) have been widely documented. In general, the literature confirms that IPO are under-priced thus causing abnormal positive initial returns (returns above those of the benchmarks) and that the long-run IPO returns fall behind the returns of the benchmark. Evidence also suggests that investors are over-optimistic about companies issuing equity, and this is true despite the form of issuance: IPO, private or seasoned placement. The reputation of the underwriter is also found to affect the under-pricing and the long run return of the IPO.
The relationship between capital structure and profitability of listed non financial firms in Kenya

v TABLE OF CONTENTS . vi LIST OF TABLES . viii ABBREVIATIONS . ix CHAPTER ONE: INTRODUCTION . 1 1.1 Background . 1 1.2 Research Problem . 8 1.3 Research Objective . 10 1.4 Value of the Study . 11 CHAPTER TWO: LITERATURE REVIEW . 12 2.
Stent-Assisted Embolization of Wide-Neck Anterior Communicating Artery Aneurysms: Review of 21 Consecutive Cases

BACKGROUND AND PURPOSE: Anterior communicating artery (AcomA) aneurysm is the most frequent form of aneurysm. Stent placement is particularly difficult and of limited use for AcomA aneurysms. We report our experience with stent-assisted embolization for wide-neck AcomA aneurysms in 21 patients. Particular attention is given to the morphologic characteristics and strategy of stent deployment. MATERIALS AND METHODS: Between January 2005 and February 2008, stent-assisted coiling was performed in 21 patients with wide-neck AcomA aneurysms. Patient demographics, aneurysm morphology, procedures, and clinical and angiographic outcomes were retrospectively reviewed. RESULTS: Successful deployment of the stent in the targeted artery was achieved in all patients. Nineteen Neuroform 2 or Neuroform 3 stents and 2 LEO stents were used. The distal segment of the stent was positioned in the ipsilateral A2 in 12 patients, in the contralateral A2 across the AcomA in 5 patients, and into the aneurysm sac in 4 patients. Complete occlusion was achieved in 18 patients; near-complete occlusion, in 2 patients; and partial occlusion, in 1 patient. Intraoperative perforation of the aneurysm developed in 1 patient, which was secured by subsequent coiling. Angiographic follow-up in 12 patients for 6.9 months showed 1 recanalization and no in-stent stenosis. CONCLUSIONS: Our preliminary results suggest that stent-assisted embolization for wide-neck AcomA aneurysms is technically feasible and safe. Further follow-up is needed for long-term efficacy of stent placement.
Experience of a large series of mastoscopic axillary lymph node dissection

Minimally invasive and functional therapy represents an inevitable trend in breast surgery. Improved visualization during mastoscopic axillary lymph node dissection (MALND) realizes a clear exposure of axillary anatomy, but it differs from a general laparoscopic operation. There are some challenges in technique itself which need to be noted. Detailed understanding of the elaborate operative technique, familiarity with the axillary anatomy and accurate adherence to procedure are main elements for successful MALND. Based on our experience of MALND, we have identified several points that are essential in ensuring successful MALND.
Genetic analysis of antibiotic-resistance determinants in multidrug-resistant Shigella strains isolated from Chilean children

A total of 162 clinical isolates of Shigella collected from children in a semi-rural community of Chile were examined for the presence of genetic determinants of resistance to ampicillin, chloramphenicol, tetracycline, and trimethoprim. Ampicillin resistance was most frequently associated with the presence of blaOXA in S. flexneri and with blaTEM in S. sonnei. The blaOXA gene but not blaTEM was located in class 1 integrons. The dhfrIa gene encoding for resistance to trimethoprim was associated to class 2 integrons and detected exclusively in S. flexneri, whereas dhfrIIIc was found in all S. sonnei strains and in 10% of the S. flexneri isolates. Cat, coding for choramphenicol resistance, and blaOXA genes were located in the chromosome in all cases, whereas tetA gene, coding for tetracycline resistance, and blaTEM, dhfrIa and dhfrIIIc genes were found either in the chromosome or in conjugative plasmids. Our results show a heterogenous distribution of antibiotic-resistance determinants between S. flexneri and S. sonnei.
Adapting to aquaculture in Vietnam: securing livelihoods in a context of change in two coastal communities

This chapter examines the effects of aquaculture development on the livelihoods of households in two historically and geographically distinct coastal communities in north and south Vietnam. It is shown that the importance of open-access resources for livelihoods increases in line with the poverty and vulnerability of the social group. This increase has occurred at the same time as a decrease in the availability of open-access products because of the privatization of resources associated with aquaculture. Many openaccess resources are accessed illegally or with unofficial access rights and this has implications for livelihood security, since open-access resources have uncertain rights and legislative status, a status that is open to change and frequently subject to privatization. The high capital investment required and the loans necessary to raise that capital are also increasing the vulnerability of the wealthier households involved in aquaculture.
Tocotrienols: A Family of Molecules with Specific Biological Activities

Vitamin E is a generic term frequently used to group together eight different molecules, namely: α-, β-, γ- and δ-tocopherol and the corresponding tocotrienols. The term tocopherol and eventually Vitamin E and its related activity was originally based on the capacity of countering foetal re-absorption in deficient rodents or the development of encephalomalacia in chickens. In humans, Vitamin E activity is generally considered to be solely related to the antioxidant properties of the tocolic chemical structure. In recent years, several reports have shown that specific activities exist for each different tocotrienol form. In this short review, tocotrienol ability to inhibit cancer cell growth and induce apoptosis thanks to specific mechanisms, not shared by tocopherols, such as the binding to Estrogen Receptor-β (ERβ) and the triggering of endoplasmic reticulum (EndoR) stress will be described. The neuroprotective activity will also be presented and discussed. We propose that available studies strongly indicate that specific forms of tocotrienols have a distinct mechanism and biological activity, significantly different from tocopherol and more specifically from α-tocopherol. We therefore suggest not pooling them together within the broad term “Vitamin E” on solely the basis of their putative antioxidant properties. This option implies obvious consequences in the assessment of dietary Vitamin E adequacy and, probably more importantly, on the possibility of evaluating a separate biological variable, determinant in the relationship between diet and health.
Distinct pathogenic effects of group B coxsackieviruses on human glomerular and tubular kidney cells

The six group B coxsackieviruses (CVBs) are highly prevalent human pathogens that cause viremia followed by involvement of different organs. Clinical and experimental evidence suggests that CVBs can induce kidney injury, but the susceptibility of human renal cells to these viruses is unknown. By using pure cultures of human glomerular and tubular cells, we demonstrated that all CVBs are capable of productively infecting renal cells of three different histotypes. Distinct pathogenic effects were observed. Proximal tubular epithelial cells and, to a lesser extent, glomerular podocytes were highly susceptible to CVBs; in both cases, infection led to cytolysis. In contrast, glomerular mesangial cells supported the replication of the six CVBs but failed to develop overt cytopathologic changes. Mesangial cells continued to produce infectious progeny for numerous serial subcultures (i.e., more than 50 days), especially with type 1, 3, 4, and 5 viruses. In the above cells, persistent infection induced the de novo synthesis of platelet-derived growth factor A/B and enhanced the release of transforming growth factor beta1/2. These two factors are important mediators of progression from glomerular inflammation to glomerulosclerosis. CVB replication appeared also to impair the phagocytic and contractile activity of mesangial cells. Loss of these properties--which are important in glomerular physiopathology--may contribute to the development of progressive nephropathy. The results show that CVBs induce distinct effects in different types of cultured renal cells and suggest that CVB infections may be associated with both acute and progressive renal injury.
Market Value Maximizing Ownership Structure When Investor Protection is Weak

We hypothesize that in a country with lax corporate governance rules Tobin's Q is maximized when controlholders’ vote approaches the supermajority level. In this holding range, controlholders do not possess extreme power (cannot pass supermajority decisions), nor do they feel a strong temptation to loot the firm (which largely belongs to them). Using a sample of 144 Israeli firms, we find that Tobin's Q is maximized when control group vote reaches 67%. This evidence is strong when ownership structure is treated as exogenous and weak when it is considered endogenous. Other ownership structure variables do not appear to have a significant valuation effect.
Mechanism of genistein in the regulation of pancreatic beta-cell proliferation

This study was designed to examine the effect of genistein, a botanical derived primarily from legumes, on pancreatic β-cell proliferation and the related molecular mechanisms. Diabetes mellitus is a major and growing public health problem worldwide. Both in type 1 (T1D) and type 2 diabetes (T2D), the deterioration of glycemic control over time is primarily caused by an inadequate mass and progressive dysfunction of β-cells. Therefore, the search for novel, safe and cost-effective agents that can enhance islet β-cell proliferation, thereby preserving β-cell mass, could be one of the essential strategies to prevent diabetes, given that β-cells have the potential to regenerate by proliferation of pre-existing β-cells in both physiological condition and after onset of diabetes. Genistein has various biological actions. However, studies on whether genistein has an effect on pancreatic β-cell function are very limited. Our laboratory recently found that genistein activates cAMP/protein kinase A (PKA) signaling in both clonal β-cells and mouse islets. Here I present evidence that genistein induced cellular proliferation of clonal rat pancreatic β-cells (INS1) and human islets following 24 h of incubation. This effect was dose-dependent with 5 μM genistein inducing a maximal 41% increase. The effect of genistein on cell proliferation was not dependent on estrogen receptors because this effect was not blocked by the estrogen receptor inhibitor ICI182,780. In addition, the genistein effect on β-cell proliferation was not shared by 17-β-estradiol or a host of structurally related flavonoid compounds, suggesting that this genistein action is structure-specific. Pharmacological or molecular intervention of PKA or MEK1/2, the upstream kinase of p42/44 mitogen activated protein kinases (ERK1/2), completely abolished the genistein-stimulated proliferation of INS1 cells and human islets, suggesting that both molecules are essential for genistein action. Consistent with its effect on cell proliferation, genistein increased intracellular cAMP and subsequently activated PKA in human islets. Genistein also caused a rapid and sustained phosphorylation of ERK1/2 with a maximal increase of 185% at 5 μM genistein. The genistein-induced ERK1/2 activation was completely ablated by inhibition of PKA in INS1 cells and human islets. Furthermore, I found that genistein induced protein expression of cyclin D1, a nuclear target of PKA and ERK1/2 activation and a major cell-cycle regulator essential for β-cell growth. These findings demonstrated that genistein may be a plant-derived growth factor for pancreatic β-cells involving induction of cyclin D1 via activation of the cAMP/PKA-dependent ERK1/2 signaling pathway, thereby providing a novel role for genistein in the regulation of pancreatic β-cell function.