Miracle-dz/UniFAR-FTUs huggingface dataset:
Inflammatory bowel disease : diagnosis and therapeutics

1. The Influence of 20th-Century Biomedical Thought on the Origins of Inflammatory Bowel Disease Therapy * Dr. Joseph B. Kirsner, University of Chicago 2. The Changing Epidemiology of IBD * Dr. Anders Ekbom. Karolinska Institute 3. Recent Advances in the Genetics of IBD * Dr. Russell D. Cohen 4. New Paradigms in the Pathogenesis of IBD * Giorgos Barnia, Theresa Pizarro, and Fabio Cominelli 5. State of the Art Medical Treatment of the Adult Patient with IBD: The Mesalamine-based Therapies * L. Campbell Levy and Corey Seigel 6. State of the Art Medical Treatment of the Adult Patient with IBD: Modern-Use Of Corticosteroids * Wojciech Blonski, David Kotlyar, and Gary Lichtenstein 7. State of the Art Medical Treatment of the Adult Patient with IBD: The Immunomodulators * Dana Moffatt and Charles Bernstein 8. State of the Art Medical Treatment of the Adult Patient with IBD: The Biological Therapies * Stephen Hanauer 9. State of the Art Medical Treatment of the Adult Patient with IBD: Prebiotics, Probiotics, Antibiotics, and Nutritional Therapies * Richard Fedorak, Levinus Dieleman, and Karen Madsen 10. State of the Art Medical Treatment of the Pediatric Patient with IBD * Marla Dubinsky 11. State of the Art Surgical Treatment of the Patient with IBD * Roger Hurst 12. Clinical Utility of Serological Markers and Thiopurine Drug Monitoring in IBD * Raja Tamaz and Ernest Seidman 13. Caring for Women with Inflammatory Bowel Disease * Sunanda Kane and Rebecca Kowalczyk 14. Novel Radiographic Techniques in IBD Patients * Vikram Sahni and Koenraad Mortele 15. Novel Techniques in the Diagnosis of Inflammatory Bowel Disease * Shabana Pasha and Jonathan Leighton 16. Pathology Slide Show: Inflammatory Bowel Disease * Christopher Weber 17. New Findings in the Diagnosis and Prevention of Colorectal Cancer in IBD * Jami Rothe and David Rubin 18. Managing the Patient with a Fecal Diversion * Janice Colwell 19. The New Economic Reality in the World of IBD * Nanda Venu and Russell Cohen
Link traversal and reasoning in dynamic linked data knowledge bases

Typical approaches for querying structured Web Data collect (crawl) and pre-process (index) large amounts of data in a central data repository before allowing for query answering. However, this time-consuming pre-processing phase however leverages the benefits of Linked Data – where structured data is accessible live and up-to-date at distributed Web resources that may change constantly – only to a limited degree, as query results can never be current. An ideal query answering system for Linked Data should return current answers in a reasonable amount of time, even on corpora as large as the Web. Query processors evaluating queries directly on the live sources require knowledge of the contents of data sources. In this paper, we develop and evaluate an approximate index structure summarising graph-structured content of sources adhering to Linked Data principles, provide an algorithm for answering conjunctive queries over Linked Data on the Web exploiting the source summary, and evaluate the system using synthetically generated queries. The experimental results show that our lightweight index structure enables complete and up-to-date query results over Linked Data, while keeping the overhead for querying low and providing a satisfying source ranking at no additional cost.
F06 A critical evaluation of inflammatory markers in Huntington's disease plasma

Background Huntington's Disease (HD) is a progressive neurodegenerative genetic disorder characterised by motor dysfunction, cognitive decline and psychiatric disturbance. Although HD is not traditionally thought of as an inflammatory disorder, it has been shown that there is a parallel immune activation in CNS and the periphery that can be seen throughout the course of the disease (Björkqvist et al, J Exp Med 2008). The cytokines that are increased earliest in the disease course are IL-6 and IL-8, both of which are involved in the innate immune response. Aims The aim of this study is to investigate whether components of innate immunity may serve as biomarkers of disease progression in HD. Methods/Techniques We investigated the potential of several components of innate immunity, such as S100 proteins and complement factors, as biomarkers in HD by measuring their levels in plasma from healthy controls, premanifest HD and early HD subjects. The plasma samples were obtained from the TRACK-HD study. Results/Outcome S100A12 and calprotectin were increased in moderate HD compared with healthy controls. Levels of clusterin, complement factors H, 3, 3a, 4, 4a, 5, 5a and 9, α-2 macroglobulin, and α1-antitrypsin did not differ between healthy controls and HD subjects. Conclusion Of the analytes tested in this study, none showed potential as a biomarker in early stages of HD.
Managing Older Patients Safely in the Time Critical Environment of an Emergency Department

Demand for emergency department (ED) services is increasing worldwide. The fastest growth in ED presentations is by patients aged ≥65 years, currently representing 18% of all attendances. Older patients present with more complex clinical conditions and multiple co-morbidities. This means they are likely to spend more time in ED, are more likely to be admitted to hospital, and are more likely to re-attend. The Safe Elderly Emergency Discharge (SEED) project aims to determine whether current models of emergency care ensure safe discharge and facilitate optimal health outcomes for older patients; and develop a tailored evidence-based care framework applicable to Australian and international settings. Risk screening for unsafe discharge will be conducted on patients aged ≥65 years discharged home from ED. Patients will be followed for 6 months post-ED presentation to monitor health outcomes and map their care journey. Demographic, clinical, and functional characteristics will be collected. The primary outcome is unsafe discharge, defined as unplanned re-presentation/admission within 30 days of the index presentation. Secondary outcomes include unplanned ED re-presentation/hospital admission within 6 months; patient experience; change in functional status; functional decline; health service utilisation; and death within 6 months. The effectiveness of the ED discharge risk screening tools for predicting unsafe discharge will be evaluated at 30 days and 6 months. SEED will determine the risk factors for unplanned ED re-presentation/hospital admission at 30 days for patients aged ≥65 years presenting to ED; which will inform the development of an evidence-based older patient care framework for EDs.
Thoracic aorta aneurysm-endovascular aortic repair.

Endovascular aortic repair (EVAR) is the treatment of choice for patients with descending thoracic aortic aneurysm who are unfit for open surgery. We report a 50-year-old Asian woman who presented with a saccular symptomatic thoracic aortic aneurysm and underwent EVAR with a covered stent with prompt relief of symptoms and no residual complications at 1 year of follow up.
Manejo Alimentar na Larvicultura do Jundiá (Rhamdia voulezi)

O presente trabalho teve como objetivo determinar o periodo ideal de fornecimento de artemia na larvicultura de jundia Rhamdia voulezi, sobre a sua sobrevivencia e desempenho. O estudo foi realizado no Laboratorio de Aquicultura da Universidade Estadual do Oeste do Parana, com quatro tratamentos e cinco repeticoes, os tratamentos foram constituidos atraves da alimentacao com artemia em 5, 10, 15 e 20 dias, depois sua substituicao pela racao. Foram utilizadas 200 larvas distribuidas em 20 aquarios. A alimentacao com artemia durante 15 dias proporcionou os melhores resultados de ganho de peso, comprimento final e sobrevivencia.
Circulating Osteonectin and Adipokine Profiles in Relation to Metabolically Healthy Obesity in Chinese Children: Findings From BCAMS

Background The role of adipokine dysregulation in determining the metabolic fate of obesity is not well studied. We aimed to examine whether the matricellular protein osteonectin and the profiles of certain adipokines could differentiate metabolically healthy obese (MHO) versus metabolically unhealthy obese phenotypes in childhood. Methods and Results This study included 1137 obese children and 982 normal‐weight healthy (NWH) controls recruited from the BCAMS (Beijing Child and Adolescent Metabolic Syndrome) study. MHO was defined by the absence of insulin resistance and/or any metabolic syndrome components. Six adipokines—osteonectin, leptin, adiponectin, resistin, FGF21 (fibroblast growth factor 21), and RBP‐4 (retinol binding protein 4)—were assessed. Approximately 20% of obese children displayed the MHO phenotype. MHO children had a more favorable adipokine profile than metabolically unhealthy obese children, with lower osteonectin, leptin, and RBP‐4 and higher adiponectin (all P<0.05). Compared with normal‐weight healthy controls, MHO children displayed increased leptin, resistin, and RBP‐4 levels and reduced adiponectin concentrations (all P<0.05) but similar osteonectin and FGF21 levels. Among obese subjects, decreased osteonectin (odds ratio [OR]: 0.82; 95% confidence interval [CI] per standard deviation, 0.70–0.97), RBP‐4 (OR: 0.77; 95% CI per standard deviation, 0.64–0.93), and leptin/adiponectin ratio (OR: 0.58; 95% CI per standard deviation, 0.43–0.77) were independent predictors of MHO. In addition, compared with children without abnormalities, those with any 3 adipokine abnormalities were 80% less likely to exhibit the MHO phenotype (OR: 0.20; 95% CI, 0.10–0.43) and 3 times more likely to have metabolic syndrome (OR: 2.77; 95% CI, 1.52–5.03). Conclusions These findings suggest that dysregulation of adipokines might govern the metabolic consequences of obesity in children. Low osteonectin levels, along with a healthy adipokine profile, might be used as an early marker of the MHO phenotype.
Media and Monarchy in Sweden

In this book, nine scholars from six different academic disciplines study various relations between media and monarchy in Sweden from the fifteenth century up until today. With an emphasis on the last one and a half century, the texts primarily analyzes how the Bernadotte family has responded to and used media such as press, film, television and Internet.
Factors that influence young adults' online security awareness.

Online fraud is aggressively threatening individuals and some believe that it can turn into a weapon of electronic warfare in the near future. There is strong agreement that society is required to develop its own resilience against this risk (Jakobsson & Srikwan, 2008). Vast sums are spent by both the government and business sectors on deflecting mechanisms and on cleaning up after online attacks which are becoming increasingly sophisticated and diverse (Gartner, 2009). The goal of this exploratory study was to establish what the factors that influenced online security were amongst young South African, Durban based adults. The conceptual framework used to guide this approach was Protection Motivation Theory (Rogers, 1983). Data for this study was collected via an online survey. The questionnaire was e-mailed to prospective participants at the University of KwaZulu Natal, where they could submit it electronically. The survey was also sent to the researchers Facebook friends and Twitter followers who fitted the criteria. Significant findings were that gender, race and employment status affected user awareness of online security. Peer Reviewed Sapsi Accredited Conference Abstract accepted for the ISSA 2013 conference that is to be held in Johannesburg on the 14 th – 16 th August 2013. Below is the abstract of this paper.accepted for the ISSA 2013 conference that is to be held in Johannesburg on the 14 th – 16 th August 2013. Below is the abstract of this paper.
Estimation of Time-Varying Parameters in Rule Systems for Music Performance

In studies of music performance, rule systems have been used to model the expressive deviations introduced by musicians. In this work we present a methodology for the estimation of the rule parameters to reproduce a given human performance as closely as possible. To achieve best fit, a least square algorithm was used. The estimation can be carried out on different time scales to improve the fit when the performer used different expressive strategies during the piece. The method has been tested on different pieces, recorded both in a controlled experiment, and also in ecological settings. Results confirm this methodology, and allow an objective comparison of parameter sets already studied in literature. The model can also be used to compare different rule systems, both from a numerical point of view, and also by listening the synthesized performances obtained using the estimated values.
Akathisia and Restless Legs

Volume 1: neural sciences neuropsychiatry and behavioural neurology contributions of psychological sciences contributions of the sociocultural sciences quantitative and experimental methods in psychiatry theories of personality and psychopathology - psychoanalysis diagnosis and psychiatry - examination of the psychiatric patient clinical manifestations of psychiatric disorders classification of mental disorders delirium, dementia and amnesia and other cognitive disorders and mental disorders due to a general medical condition substance-related disorders schizophrenia other psychotic disorders mood disorders anxiety disorders somatoform disorders fractious disorders dissociative disorders normal human sexuaity, and sexual and gender identity disorders. Volume 2: eating disorders sleep disorders impulse-control disorders not elsewhere classified and adjustment disorders personality disorders psychologic factors affecting medical condition (psychosomatic disorders) relational problems additional problems that may be a focus of clinical attention psychiatry and other specialties psychiatric emergencies psychotherapies biological therapies child psychiatry psychiatric examination of the infant, child and adolescent mental retardation learning disorders, motor skills disorders, and communication disorders pervasive developmental disorders attention-deficit disorders disruptive behaviour disorders feeding and eating disorders of infancy and early childhood TIC disorders elimination disorders other disorders of infancy, childhood and adolescence mood disorders and suicide schizophrenia with childhood onset child psychiatry - psychiatric treatment child psychiatry - special areas of interest adulthood geriatric psychiatry hospital and community psychiatry psychiatric education forensic psychiatry psychiatry - past and future epilogue.
A mental health survey of community correctional clients in Canada

Probation and parole officers completed a brief survey questionnaire on 2500 community correctional clients, who were randomly selected from a total caseload of 60 000 active files. The survey instrument inquired about the mental health histories and the clinical or programme needs of these clients, most of whom (76.5%) were on probation. Among the sample, 13.2% had a known psychiatric diagnosis, including 5.0% who had been diagnosed with a schizophrenic illness, bipolar disorder or mental retardation. A total of 6.4% had at least one documented psychiatric hospitalisation. Subjects with a history of hospitalisation had an average of 4.6 psychiatric admissions and an average total of 73.2 days' stay in mental health facilities. A total of 9.0% had a rating on the Global Assessment of Functioning scale that indicated serious mental health symptoms or serious social impairment, whilst 2.0% were rated as being suicidal, grossly impaired or delusional. Collectively, 18.9% met at least one of the three criteria, whilst 8.3% of the subjects met two or more of the criteria. Disordered clients were more likely than their non-disordered counterparts to have inadequate accommodation, to live alone, and to be in an institution or on social assistance and less likely to be employed or in school. According to staff ratings, the commonest need areas for the disordered offenders were general counselling, alcohol/drug programmes, psychological services, life/social skills training, psychiatric assessment and employment. Needs were most likely to be met for medical problems and least likely for non-clinical, social services. Refusal, lack of motivation, dropping out from a service and unsuccessful previous participation accounted for approximately one-half of the unserviced needs. The importance of integrating services between health, corrections and social service agencies for disordered offenders is highlighted. Copyright © 1996 Whurr Publishers Ltd.
Evaluating Teaching and Learning: A practical handbook for colleges, universities and the scholarship of teaching

Acknowledgements 1. Evaluation Principles 2. Questionnaire design 3. Questionnaires 4. Item Bank 5. Collecting and Processing Questionnaire Data 6. Collection of Qualitative Data 7. Analysis of Qualitative Data 8. Observation 9. Use of Assessment for Evaluation 10. Using Evaluation Data for the Scholarship of Teaching 11. International Perspectives on Teaching Evaluation 12. Institutional Use of Teaching Evaluation Data 13. Conclusion
Factorial structure of SILL revisited: adaptation of SILL for Estonian EFL learners

DOI: http://dx.doi. org/10.5128/ERYa11.15 The present study aims to contribute to the understanding of the taxonomy of language learning strategies (Oxford 1990: 14–22) and its measuring instrument, the Strategy Inventory for Language Learning (SILL), through the adaptation process of the Estonian version. The translated version of the SILL was pilot-tested with a sample of 337 tertiary students. Cronbach’s alpha (0.91) reveals an acceptable reliability of the instrument. The t-test that was conducted in addition to descriptive analysis, to check for gender differences, did not reveal any significant differences. The results of the exploratory factor analysis did not support the 2- or 6-factor structures but the 9-factor analysis provides a good comparison to similar studies published in 1995 (Oxford, Burry-Stock 1995). The ethnic and gender differences of the results are discussed from the cultural perspective.
Blood Viscosity of the Neonate

After completing this article, readers should be able to: 1. List the determinants of blood viscosity in the neonate. 2. List the causes of polycythemia and hyperviscosity in the neonate. 3. List the signs, symptoms, and diagnostic criteria for polycythemia and hyperviscosity. 4. Describe steps for prevention and treatment of polycythemia and hyperviscosity in the neonate. Blood viscosity is defined as resistance to the movement of blood. In a circular vessel or tube, the resistance (R) increases with increasing viscosity (V) of the moving fluid and with the resistance resulting from the vessel geometry (Z): R=Z · V. Thus, blood viscosity describes the contribution of blood rheologic factors to blood flow resistance. However, blood viscosity depends on several factors, and the importance of these factors differs among various vessels. The major determinants of blood viscosity are the hematocrit, plasma viscosity, red blood cell (RBC) aggregation, RBC deformability, leukocyte properties, vessel diameter, and the shear forces acting on the RBC. (1) The hematocrit generally is assumed to be the most important determinant of blood viscosity. Blood viscosity rises exponentially with increasing hematocrit (Fig. 1). A marked rise in blood viscosity is seen when the hematocrit exceeds 0.65 L/L, which typically is defined as the threshold for hyperviscosity of the blood. However, in narrow arteries and arterioles and in capillaries, the plasma viscosity becomes the dominant determinant of blood viscosity. The fetal hematocrit increases from 0.33 L/L in the 12th week of gestation to 0.45 L/L in the 30th week and 0.50 L/L in the 40th week at term. At birth, the hematocrit may rise markedly as a result of “blood transfusion” from the placenta to the neonate. (2) A postnatal hematocrit of 0.45 to 0.65 L/L is considered normal in the healthy term neonate. Figure 1. Blood viscosity in tubes that have a diameter of 50 …
Comparative Assessment of Reduction in Discomfort by Topical Anesthetic Gels before Local Anesthetic Injections in Children: An in-vivo Study

Background: Pediatric dentists always feel the need of topical anesthetics that would make the local anesthetics administration painless for children. At present number of agents are being marketed each claiming better results. Supporting literature regarding their efficacy is lacking. Aim: The aim was to compare efficacy of 20% benzocaine and combination of 8% lidocaine + 0.8% dibucaine as flavored topical anesthetic agents in reducing discomfort by intraoral local anesthetic injections and extraction of deciduous teeth with pre shedding mobility. Methodology: Study included 30 children who were grouped under three treatment categories - Palatal injection, inferior alveolar nerve block, and extraction of pre-shedding mobile deciduous teeth. Both the products were tested for each treatment category using split-mouth design in two appointments. Pain assessment was done under visual analog scale and sound eye motor pain scale. Statistical analysis of data obtained was done using Mann–Whitney U-test. Results: 8% lidocaine + 0.8% dibucaine provides significantly better anesthesia ( P 0.5) was found in anesthesia while extracting mobile primary teeth. No significant difference ( P > 0.5) on gender wise comparison or appointment wise comparison was seen. Conclusion: 8% lidocaine + 0.8% dibucaine can be used when anesthesia is required for deeper tissue, when better penetration is required as in inferior alveolar nerve block and palatal injection.
COMBINING ON- AND OFF-CAMPUS SERVICE-LEARNING IN A STATISTICS METHODS COURSE

Many models for implementing service-learning are possible, but the issue of meeting the needs of a community service organization within an academic time frame must be considered regardless of which model is chosen. Organizational deadlines that occur too early or too late in a course can minimize the contribution of the service project to students’ learning. Expanding the definition of ‘community’ to include the academic community allows the possibility of working with student, faculty and administrative ‘clients’ across campus whose data analysis needs may agree better with the time frame available during a single course. Service-learning in this expanded definition of community can meet the necessary criteria for academic service learning: relevant and meaningful service within the community, enhanced academic learning, and purposeful civic learning.