Miracle-dz/UniFAR-FTUs huggingface dataset:
KINERJA PORTOFOLIO SAHAM BERDASARKAN STRATEGI INVESTASI MOMENTUM PADA INDUSTRI MANUFAKTUR

The purpose of this study was to determine the performance of a stock portfolio using momentum investment strategy in the manufacturing industry. The scope of this research area is the companies in the manufacturing industry listed in Indonesia Stock Exchange during the period January 2009 to December 2014. 120 samples of manufacturing companies were taken using purposive sampling method. Methods of data collection is done through non-participant observation and analysis techniques using paired sample t-test. Based on the results of data analysis found that the performance of winner portfolio was lower than the performance of loser portfolio in the period of the next possession, and then, there is a difference between the winner-loser portfolio performance in the formation period and the holding period. This indicates that the momentum investment strategy is not profitable when applied in the Indonesian capital market.
Insights on Extent of Effectiveness, Trend, and Gap in Existing Frameworks for e-Procurement System

With the advancement of technologies, the organization and business applications are witnessed with the increasing trends to adopt cut edge technologies to normalize their business process. However, this trend was not observed much on the e-Procurement system, where the existing users still place the purchase order using conventional web-based approach that cannot address various ongoing challenges in eProcurement system. This paper attempts to review the existing trends and challenges of web-based eProcurement system and discusses that with the adoption of cloud computing as present trend, such ongoing issues of eProcurement can be addressed. The paper discusses the effectiveness of the existing techniques with interpretation of research gap.
Skeletal muscle satellite cell characteristics in young and older men and women after heavy resistance strength training.

Skeletal muscle satellite cell proportions and morphology were assessed in healthy, sedentary young and older men and women in response to heavy resistance strength training (HRST). Fourteen young (20-30 years) men (n = 7) and women (n = 7) and 15 older (65-75 years) men (n = 8) and women (n = 7) completed 9 weeks of unilateral knee extension exercise training 3 days per week. Muscle biopsies were obtained from each vastus lateralis before and after training, with the nondominant leg serving as an untrained control. All four groups demonstrated a significant increase in satellite cell proportion in response to HRST (2.3 +/- 0.4% vs 3.1 +/- 0.4% for all subjects combined, before and after training, respectively; p < .05), with older women demonstrating the greatest increase (p < .05). Morphology data indicated a significant increase in the proportion of active satellite cells in after-training muscle samples compared with before-training samples and with control leg samples (31% vs 6% and 7%, respectively; p < .05). The present results indicate that the proportion of satellite cells is increased after HRST in young and older men and women, with an exaggerated response in older women. Furthermore, the proportion of satellite cells that appear morphologically active is increased as a result of HRST.
Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice

Here, we study the intricate relationship between gut microbiota and host cometabolic phenotypes associated with dietary-induced impaired glucose homeostasis and nonalcoholic fatty liver disease (NAFLD) in a mouse strain (129S6) known to be susceptible to these disease traits, using plasma and urine metabotyping, achieved by 1H NMR spectroscopy. Multivariate statistical modeling of the spectra shows that the genetic predisposition of the 129S6 mouse to impaired glucose homeostasis and NAFLD is associated with disruptions of choline metabolism, i.e., low circulating levels of plasma phosphatidylcholine and high urinary excretion of methylamines (dimethylamine, trimethylamine, and trimethylamine-N-oxide), coprocessed by symbiotic gut microbiota and mammalian enzyme systems. Conversion of choline into methylamines by microbiota in strain 129S6 on a high-fat diet reduces the bioavailability of choline and mimics the effect of choline-deficient diets, causing NAFLD. These data also indicate that gut microbiota may play an active role in the development of insulin resistance.
Estimating Aggregate Consumer Preferences from Online Product Reviews

Today, consumer reviews are available on the Internet for a large number of product categories. The pros and cons expressed in this way uncover individually perceived strengths and weaknesses of the respective products, whereas the usually assigned product ratings represent their overall valuation. The key question at this point is how to turn the available plentitude of individual consumer opinions into aggregate consumer preferences, which can be used, for example, in product development or improvement processes.To solve this problem, an econometric framework is presented that can be applied to the mentioned type of data after having prepared it using natural language processing techniques. The suggested methodology enables the estimation of parameters, which allow inferences on the relative effect of product attributes and brand names on the overall evaluation of the products. Specifically, we discuss options for taking opinion heterogeneity into account. Both the practicability and the benefits of the suggested approach are demonstrated using product review data from the mobile phone market. This paper demonstrates that the review-based results compare very favorably with consumer preferences obtained through conjoint analysis techniques.
Comparison of Polyphenol Profile and Inhibitory Activities Against Oxidation and α-Glucosidase in Mulberry (Genus Morus) Cultivars from China.

UNLABELLED Mulberry (genus Morus) is a significant source of polyphenols, which can promote positive effects on human health. China has various mulberry cultivars, however, many Chinese mulberry cultivars have been only minimally studied. To solve this lack of research, 8 mulberry cultivars (Da10, Tang10, Yueshen74, Yuefenshen, Longsang, Ningxia1hao, Taiwanguosang, and Baiyuwang) from 4 regions of China were assessed to determine their polyphenol profiles using HPLC-MS/MS and then tested for their antioxidant and anti-α-glucosidase activities in vitro. A total of 18 nonanthocyanins and 4 anthocyanins were quantified in mulberry cultivars; among these polyphenols, chlorogenic acid, quercetin 3-O-rutinoside, and cyanidin 3-O-glucoside were confirmed as the major phenolic acid, flavonol derivative, and anthocyanin, respectively. Two types of stilbene compounds, piceid, and piceatannol, were detected for the 1st time in all mulberry cultivars. Moreover, the methanolic extracts of different mulberry cultivars showed disparate antioxidant and α-glucosidase inhibitory activities, and this discrepancy was mainly attributed to varying the anthocyanin content. Based on our results, Taiwanguosang is proposed to be a good candidate suitable for further process due to its high level of anthocyanins. PRACTICAL APPLICATION The polyphenols of mulberry cultivars are vital for human health and are relevant to the further development of mulberry-based products. China has a wide range of mulberry cultivar resources, and many of these cultivars have not yet been studied. Our research concentrated on the polyphenol profiles, antioxidant, and α-glucosidase inhibitory activities of various mulberry cultivars from different regions of China to provide basic information for mulberry cultivar selection and mulberry-based food production.
Gene control of mammalian pigmentary differentiation. I. Clonal origin of melanocytes.

Background information on melanocyte development -melanocytes are clonally derived from a fixed number of primordial melanoblasts -Genes that determine the fate of these cells are activated in the early embryonic life, prior to any visible evidence of neural crest -Gene activity is stable -primordial melanoblast cells can have different cell phenotypes -when these diverse cells coexist, they follow a given arrangement so that they reproduce a color pattern
Psychic distance, marketing strategy and performance in export ventures of Brazilian firms

Compared to other issues examined in the exporting literature, less attention has been paid to the performance implications of following a standardisation or adaptation strategy. In addition, despite the interest in the psychic distance construct in the international marketing literature, there has been also little empirical research on the effect of managers' psychic distance on the international marketing strategies of the firm. To address these issues the present study offers an empirical investigation of the relationship among psychic distance, international marketing strategies, and export performance of Brazilian firms. A sample of senior managers of industrial firms in Brazil is used to test the hypotheses. The results reported here indicate that the degree of international marketing strategy adaptation is affected by the manager's psychic distance towards the foreign markets. Product and promotion adaptation were found to have a positive effect on export performance while surprisingly, distribution and price adaptation were found to influence export performance negatively. Contrary to expectations, the results also confirm that psychic distance has a positive effect on the export performance of the firm. Implications of these findings along with the limitations of the study are discussed.
IL-12-Mediated Signaling - and g Th1 Differentiation by Blocking IFN-Suppressive Oligodeoxynucleotides Inhibit

2 Repetitive TTAGGG motifs present at high frequency in mammalian telomeres can suppress Th1-mediated immune responses. Synthetic oligonucleotides (ODN) containing TTAGGG motifs mimic this activity and have proven effective in the prevention/ treatment of certain Th1-dependent autoimmune diseases. This work explores the mechanism by which suppressive ODN block the induction of Th1 immunity. Findings indicate that these ODN inhibit IFN- (cid:1) -induced STAT1 phosphorylation and IL-12-induced STAT3 and STAT4 phosphorylation. As a result, T-bet expression is reduced as is the maturation of naive CD4 (cid:2) cells into Th1 effectors. These changes indirectly support the generation of Th2-dominated immune responses. Suppressive ODN may thus represent a novel approach to inﬂuence the Th1:Th2 balance in vivo. The Journal of Immunology, 2004, 173: 5002–5007. 25 (cid:2) g/ml oligo(dT) 12–18 , 200 U Moloney leukemia virus reverse transcriptase, 2 mM dNTP, and 10 mM DTT. The reaction was conducted at 42°C for 1 h. A standard PCR was performed on 1 (cid:2) l of the cDNA synthesis for 24 cycles using the following primer pairs: mouse T-bet, CGCTGGGGCCCCTTCTCCTTTTG and CCCAGTCCGCCCGCAGT CACC and mouse (cid:4) GACATGGAGAAGATCTGGCAACCACA ATCTCCTGCTCGAAGTCTAGAGCAA. agarose visualized ethidium bromide
Predictive factors for prolonged survival in acquired immunodeficiency syndrome—associated progressive multifocal leukoencephalopathy

Progressive multifocal leukoencephalopathy (PML) complicating the acquired immunodeficiency syndrome (AIDS) is typically inexorably progressive with death usually occurring within 6 months of symptom onset. Occasional patients have been observed to survive longer than 1 year, often with remission of clinical features. In this study, we identify predictive factors for prolonged survival in patients with biopsy proven, AIDS‐associated PML, by comparing 7 patients with survival exceeding 12 months from symptom onset with 45 patients with shorter survivals. PML was the presenting manifestation of AIDS in 5 (71.4%) of 7 long‐term survivors compared with 8 (17.8%) of 45 short‐term survivors. CD4 T‐lymphocyte counts were substantially higher in the long‐term survivors, with 3 (42.9%) of 7 having counts exceeding 300 cells/mm3 in comparison with only 1 (4.3%) of 23 short‐term survivors. Contrast enhancement on radiographic imaging was observed in 3 (50%) of 6 long‐term survivors in comparison with 4 (8.9%) of 45 short‐term survivors. Neurological recovery and radiographic improvement were not observed in any short‐term survivors but were seen in 5 (71.4%) long‐term survivors. There was no association between treatment modalities and survival. Predictors of long‐term survival in AIDS patients with PML include PML as the heralding manifestation of AIDS, high CD4 T‐lymphocyte count at disease onset, lesion enhacement on computed tomographic scan or magnetic resonance imaging, and evidence of recovery of neurological function.
Influence of supply chain model on quality and safety control of table grape and performance of small‐scale vinegrowers in China

Purpose – Table grape is one of the most important horticultural crops in China. However, quality and safety have become major constraints for the further development of the Chinese table grape industry, which is dominated by small‐scale vinegrowers. Strategic partnership has been regarded as an effective mechanism to manage the supply chain. The purpose of this paper is to examine the impact of a supply chain model based on different strategic partnerships on the effect of safety and quality control and small‐scale vinegrowers' performance.Design/methodology/approach – The field survey was performed in seven representative districts in China, including Inner Mongolia, Gansu, Tianjin, Liaoning, Shandong, Jiangsu and Zhejiang Provinces. A semi‐structured interview was adopted as the data collection method. Both quantitative and qualitative data were generated and analyzed in this research. All quantitative analyses were conducted using EXCEL 2003 version and a comparative analysis was conducted to test the.
Regulation of p26-bcl-2 protein levels in human peripheral blood lymphocytes.

BACKGROUND The protein encoded by the bcl-2 (B cell lymphoma/leukemia-2) proto-oncogene has been implicated in the regulation of lymphocyte cell survival and has been shown to interfere with programmed cell death (apoptosis). Recently, controversy has emerged regarding the expression of bcl-2 in circulating peripheral blood lymphocytes (PBL) and its correlation with lymphocyte proliferation. Using immunohistochemical methods, Pezzella et al. (Pezzella F, Tse G, Cordell J, Pulford K, Gatter K, Mason D. Am J Pathol 1990; 137:225-32) detected abundant amounts of Bcl-2 protein in resting PBLs and observed an inverse correlation between bcl-2 expression and cellular proliferation in lymphoid tissues. In contrast, previous in vitro studies of bcl-2 mRNAs showed that expression of this gene is very low in unstimulated PBLs but can be markedly induced when lymphocytes are stimulated to proliferate in culture (Reed JC, Tsujimoto Y, Alpers JD, Croce CM, Nowell PC. Science 1987; 236:1295-9; Granniger W, Seto M, Boutain B, Goldman P, Korsmeyer S. J Clin Invest 1987; 80:1512-5). EXPERIMENTAL DESIGN To resolve this issue, the regulation of p26-Bcl-2 protein levels was examined in freshly isolated and in cultured human PBLs by immunoblotting using two different polyclonal antisera specific for the human Bcl-2 protein. RESULTS When freshly isolated from whole blood, resting PBLs contained easily detectable amounts of p26-Bcl-2 protein that did not significantly change in culture when cellular proliferation was stimulated with mitogenic lectins and lymphokines. If processing of the blood was delayed, however, p26-Bcl-2 protein was low or undetectable in resting PBLs and underwent marked increases in its relative levels after in vitro stimulation of PBLs by mitogenic lectins and lymphokines. CONCLUSIONS The findings indicate that bcl-2 is normally expressed in quiescent circulating lymphocytes, consistent with a role for this gene in the maintenance of lymphocyte survival, and illustrate the importance of correlating in vitro and in vivo expression data.
The influence of supply chain collaboration on collaborative advantage and port performance in maritime logistics

ABSTRACT Although many academics and practitioners in the maritime industry have recognised the importance of supply chain collaboration (SCC) between ports and port users, there is still a lack of empirical work on this issue. This work empirically investigates the association between SCC, collaborative advantage and port performance in a maritime logistics context. Data were collected via a web-based questionnaire survey which engaged 178 responses from maritime logistics firms in South Korea. Hypotheses were tested by using structural equation modelling, following a hierarchical analysis process. The results confirm that SCC has positive impacts on collaborative advantage, which in turn helps to improve port performance. The finding indicates that collaborative advantage has a full mediation effect on the link SCC-port performance. This work invites managers to recognise the positive outcomes of inter-organisational SCC practices in enhancing collaborative advantage and port performance within port supply chain.
Banner advertising: Measuring effectiveness and optimizing placement

The article describes how one company improved banner advertising response rates by taking advantage of the medium's rich data to optimize placement. The study identified Web surfers who were frequent visitors to the banner advertiser's site. It then identified 100 Websites that these surfers tended also to visit. These sites were cluster analyzed to yield site genre definitions (affinities). In this manner a model was built to identify a group of affinities whose visitors were disproportionately likely to respond to banner advertising. These predictions were tested by placing banners on sites forecast to perform well. The average cost per response was nine times lower for sites predicted to belong to high affinity groups than low groups.
Cognitive Rehabilitation of Schizophrenia Through Neurovr Training

Cognitive difficulties are prevalent in people with diagnosis of schizophrenia and are associated with poor long-term functioning. In particular, memory, selective, divided and sustained attention and executive functions are altered by this disease. We used a Virtual Reality environment (developed via the NeuroVr2.0 software) for the rehabilitation of shifting, sustained attention and action planning functions using tasks reminiscent of daily life tasks. Test and retest showed significant differences in the assessed cognitive dimensions.
Inhibition of IFN-γ-Induced STAT1 Tyrosine Phosphorylation by Human CMV Is Mediated by SHP21

Human CMV (HCMV) is a ubiquitous β-herpesvirus which has developed several mechanisms of escape from the immune system. IFN-γ-induced signaling relies on the integrity of the JAK/STAT pathway which is regulated by phosphorylation steps and leads to nuclear translocation of tyrosine-phosphorylated STAT1 (STAT1-P-Tyr), and its binding to IFN-γ activation site sequences of IFN-γ-inducible promoters. Activation of those promoters leads to the expression of genes involved in the immune response and in the antiviral effects of IFN-γ. Src homology region 2 domain-containing phosphatase 2 (SHP2) is a ubiquitous phosphatase involved in the regulation of IFN-γ-mediated tyrosine phosphorylation. Several mechanisms account for the inhibition IFN-γ signaling pathway by HCMV. In this study, we have identified a new mechanism that involved the inhibition of STAT1 tyrosine phosphorylation within 12–24 h postinfection. This defect was dependent on HCMV transcription. Consequences were impaired nuclear translocation of STAT1-P-Tyr, inhibition of IFN-γ activation site-STAT1 interaction, and inhibition of HLA-DR expression. Expression of indoleamine-2,3-dioxygenase which is involved in the antiviral effects of IFN-γ was also inhibited. Treatment of cells with sodium orthovanadate rescued STAT1 tyrosine phosphorylation, suggesting that a tyrosine phosphatase was involved in this inhibition. Coimmunoprecipitation of STAT1 and SHP2 was induced by HCMV infection, and SHP2 small interfering RNA restored the expression of STAT1-P-Tyr. Our data suggest that SHP2 activation induced by HCMV infection is responsible for the down-regulation of IFN-γ-induced STAT1 tyrosine phosphorylation.
Flow-diversion for ophthalmic segment aneurysms.

BACKGROUND The use of flow-diversion to treat ophthalmic segment aneurysms (OSA) has not been well evaluated. OBJECTIVE To assess the visual outcomes, the obliteration rate, and the need for retreatment of OSA treated by the pipeline embolization device (PED). METHODS Patients who underwent treatment with PED for OSA from 2009 to 2014 were selected and retrospectively reviewed. Patient's age, sex, mode of presentation, and aneurysm size were recorded. The complication rates, the need for retreatment (due to recurrence of the aneurysm or worsening symptoms), the aneurysm occlusion rates, the evolution of visual symptoms, and the evolution of headache/retro-orbital pain were registered. RESULTS Forty-one patients harboring 44 OSA treated by flow-diversion were identified. Females constituted 87.80% (37/41) of the cohort. The mean age was 59.16 ± 12.54 years. At final angiographic follow-up, 77.27% (34/44) had complete occlusion, 6.81% (3/44) had near-complete occlusion, and 15.90% (7/44) had incomplete occlusion. Of the 22 symptomatic OSA, complete resolution or significant improvement was noted in 72.72% (16/22), while worsening of symptoms occurred in 4.54% (1/22). Five patients out of 22 (22.72%; 5/22) had no significant changes in their symptoms. The complication rate was 2.27% (1/44). The mortality rate was 0%. CONCLUSION The low complication rate, the high obliteration rate, and the high rate of improvement in the visual symptoms make flow-diversion an appealing option for the treatment of OSA.
Supply chain transparency as a key prerequisite for sustainable agri-food supply chain management

This paper discusses the antecedences and consequences of supply chain transparency (SCT) in sustainable agrarian supply chain management using partial least squares regression in an empirical sample with 131 supply chains with lead firms in German-speaking countries (Germany, Austria and Switzerland). We investigated the effect of such structural antecedences as disintermediation, as well as the effect of governance tools similar to intensive communication, the integration of third parties in supply chain governance or the use of formal specifications on SCT. We found that all these antecedences are helpful in increasing SCT, while low developed countries of origin significantly reduced SCT. Then, the effects of SCT on the four main performance dimensions in sustainable supply chain management (SSCM), i.e. social, ecological, and operational performance and long-term relationship success, were verified. Higher SCT improves all four dimensions significantly, while the effect on operational performance is lowest. Supply chain transparency turns out to be a prerequisite or a basic indicator of good management in SSCM in agri-food supply chains.