Miracle-dz/UniFAR-FTUs huggingface dataset:
The Effectiveness Of Yoga To Decrease Blood Pressure In Elderly With Hypertension In Tresna Werdha Khusnul Khotimah Nursing Homes Pekanbaru

Uncontrolled hypertension increase the incidence of stroke disease by 7 times, congestive heart failure by 6 times, and heart attack by 3 times. About 74% elderly in Indonesia who from chronic hypertension consumed pharmacological medicine during their life that had some adverse effects. Therefore, nonpharmacological intervention such as simple yoga exercise can prevent the complications in elderly. The objective of this research was to find out the The effectiveness of yoga to decrease blood pressure in elderly with hypertension in Tresna Werdha Khusnul Khotimah Nursing Homes Pekanbaru. The research design was quasi-experimental research by using pretestposttest design with control group. Total sample were 34 respondents by using purposive sampling. The research used univariat and bivariate analysis by using wilcoxson test to find out pretest result of experimental and control group, mann-whitney test to find out posttest result of experimental and control group. The results showed that the difference between systole blood pressure before (pretest) and after (posttest) of experimental group was significant with p-value 0,000 and diastole with p-value 0,000. Results also showed that mean rank systolic experimental group was 21,40 mmHg and 14,42 mmHg in control group with p-value 0,043 (<0,05), while that mean rank of diastolic experimental group was 21,60 mmhg and 14,26 mmHg to the control group with p-value 0,033 (<0,05). It can be concluded that yoga intervention effective toward decreasing of blood pressure in elderly with hypertension. This research recommends that yoga can be used as a therapy to decrease blood pressure in elderly with hypertension.
A Double-Blind, Randomized Controlled 12-Week Follow-Up Trial to Evaluate the Efficacy and Safety of Polycan in Combination with Glucosamine for the Treatment of Knee Osteoarthritis

Aim The aim of the present study was to examine the efficacy and safety of Polycan, a β-glucan produced from the black yeast Aureobasidium pullulans SM-2001, in combination with glucosamine in reducing knee osteoarthritis-associated symptoms. Methods This was a double-blind, randomized controlled trial of a formulated product composed of 16.7 mg of Polycan and 250 mg of glucosamine (Group A), 16.7 mg of Polycan and 500 mg of glucosamine (Group B), or 500 mg of glucosamine (control group) per capsule, administered as three capsules once per day over a period of 12 weeks, conducted with 100 osteoarthritis patients, aged 35–80 years. The primary outcome measure was osteoarthritis symptoms assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire. The secondary outcome measures included rescue medication use (according to data from a patient-reported diary) and other safety indices (body weight, blood pressure, hematological, and biochemistry markers). Results Compared with the control group, Group B demonstrated a statistically significant reduction in the total WOMAC score after 12 weeks of treatment (p < 0.05). There was a significant reduction in the frequency of rescue medication used in Groups A and B compared with the control group (p < 0.05). There were no significant changes in hematology and biochemistry parameters or health indices between the active and the control group. Conclusion Among patients with mild or moderate osteoarthritis, a daily oral dose of Polycan (50 mg) in combination with glucosamine (750 mg or 1500 mg; Group A or B, respectively) resulted in a better treatment outcome than treatment with glucosamine (1500 mg) alone.
TOJDE: Electronic Publishing and a Review of Ten Years’ Experience in Turkey

This review examines The Turkish Online Journal of Distance Education (TOJDE) over a ten years period from 2000-2010. The study provides an opportunity to examine publishing activities such as number of published articles, authors, research topics and methods, and analyses of TOJDE’s website such as time users stay on site and user profiles. After a content analysis, the articles are reviewed according to the selected criteria. These data were categorized according to emerging themes. Most parts of the data were analysed using descriptive statistics, and presented with tables and figures. The results can be used to review current distance education research trends and to explore potential research directions.
Etiology and Outcome of Open Fractures of the Extremities: A Single Center, Retrospective Study of 287 Patients

Objectives To retrospectively evaluate the incidence, mechanism of injury and outcome of all consecutive open fractures of the extremities in patients treated in Ndjamena (Chad) at Hopital de l’Amitie Tchad-Chine, a single medical center between August 1, 2013, to August 31, 2014. Materials and methods In 1 year interval, 287 patients (198 males and 89 females) with open fractures were admitted in this trauma center. A retrospective analysis was conducted on data obtained from the medical records, including patient’s age, sex, mechanism of injury, types of fractures, grades of fractures, surgical interventions and complications. Results Among 302 patients admitted with fractures of the extremities during 1year of the study period, 287 patients had open fractures with an incidence rate of 95.03%. Road traffic accidents were the commonest injuries with 50.52%, followed by interpersonal violence 14.98%, construction site 12.54%, falls from height 11.50% and sports injury 10.45%. Upper limb injuries were 39.38% and Lower limb 60.62%. Surgical debridement, plaster mobilization, external and internal fixation were used in the management of those patients. Only 1 patient was amputated. Conclusion As lower limb was the most injured part, an early surgical debridement with frequent use of external fixators devices can definitely minimize the rate of complications in such patients. Road safety awareness should be instilled in order to reduce the rate of mortality and morbidity.
Thymic lesions of the paediatric age group: a comprehensive review of non-neoplastic and neoplastic etiologies

Thymus is an important part of the immune system of the paediatric age group. Thymic lesions are rare causes of anterior mediastinal pathology. Their occurrence in children is rarer, nevertheless, knowledge about their pathologies help in clinching the correct diagnosis. All lesions both non-neoplastic as well as neoplastic are found in children, however, they differ from adults not only in the clinical presentation but also in the pathogenesis and natural history of the disease. Thymic hyperplasia may not actually be true if age is taken into consideration. Similarly, a type B thymoma may be mistakenly diagnosed as a lymphoblastic lymphoma especially on small biopsies. This review has been carried out after extensive search of literature using the Google and Pubmed search engines. An attempt has been made to comprehensively cover all aspects of thymic pathology of the paediatric age group having historical significance as well as the recent updates.
Differential Analysis of Hypertension-Associated Intestinal Microbiota

Hypertension is the main risk factor for cerebral stroke and death resulting from cerebral stroke. Current association studies on hypertension and intestinal microbiota focus on patients with hypertension (HTN); however, no investigations involving patients with isolated diastolic hypertension (IDH) or systolic hypertension (SH) have been conducted to date. In this study, fecal samples from 62 cases with normal blood pressure (BP) and 67 cases with high BP were used for 16S amplicon sequencing. Sixty-one cases of HTN and 61 corresponding cases with normal BP were obtained by propensity score matching (PSM), and differential analysis was conducted using the DEseq2 package. PSM was also used to match six IDH patients with six controls and to match 35 cases of SH with 35 controls. There were 54 differential genera between the HTN and normal BP groups, and there were five differential genera between the IDH and normal BP groups. There were 38 differential genera between the SH and normal BP groups, including Christensenella. Bayesian network analysis showed that variations in BP influenced microbial abundance. Pearson's correlation analysis showed that bacterial abundance is correlated with BP. Significant differences between the intestinal microbiota of high and normal BP groups were observed. Gut microbiota dysbiosis differed among HTN, IDH, and SH patients. In particular, diastolic blood pressure (DBP) and systolic blood pressure (SBP) were related to different intestinal microbiota.
Computer-Aided Detection for Breast Cancer Screening in Clinical Settings: Scoping Review

Background With the growth of machine learning applications, the practice of medicine is evolving. Computer-aided detection (CAD) is a software technology that has become widespread in radiology practices, particularly in breast cancer screening for improving detection rates at earlier stages. Many studies have investigated the diagnostic accuracy of CAD, but its implementation in clinical settings has been largely overlooked. Objective The aim of this scoping review was to summarize recent literature on the adoption and implementation of CAD during breast cancer screening by radiologists and to describe barriers and facilitators for CAD use. Methods The MEDLINE database was searched for English, peer-reviewed articles that described CAD implementation, including barriers or facilitators, in breast cancer screening and were published between January 2010 and March 2018. Articles describing the diagnostic accuracy of CAD for breast cancer detection were excluded. The search returned 526 citations, which were reviewed in duplicate through abstract and full-text screening. Reference lists and cited references in the included studies were reviewed. Results A total of nine articles met the inclusion criteria. The included articles showed that there is a tradeoff between the facilitators and barriers for CAD use. Facilitators for CAD use were improved breast cancer detection rates, increased profitability of breast imaging, and time saved by replacing double reading. Identified barriers were less favorable perceptions of CAD compared to double reading by radiologists, an increase in recall rates of patients for further testing, increased costs, and unclear effect on patient outcomes. Conclusions There is a gap in the literature between CAD’s well-established diagnostic accuracy and its implementation and use by radiologists. Generally, the perceptions of radiologists have not been considered and details of implementation approaches for adoption of CAD have not been reported. The cost-effectiveness of CAD has not been well established for breast cancer screening in various populations. Further research is needed on how to best facilitate CAD in radiology practices in order to optimize patient outcomes, and the views of radiologists need to be better considered when advancing CAD use.
Optimizing locally the spread of influence in large scale online social networks

Optimizing the spread of influence in online social networks (OSNs) is important for the design of efficient viral marketing strategies using online recommendations. It is commonly believed that, spreading is a global process, whose optimization would require the knowledge of the whole network information. Here we uncover a characteristic local length scale, called influence radius, hidden in the global nature of spreading processes. We show that, any node's influence to the entire OSN can be quantified from its local network environment within the influence radius, which is significantly smaller than the whole network diameter. By mapping the problem onto bond percolation, we give a theoretical explanation for the presence of this short influence radius, and a framework to quantify individual's influence in real OSNs. We then propose a scalable optimization algorithm to identify the most influential spreaders. The time complexity of our algorithm is independent of network size, and its performance is remarkably close the true optimum. Our method may be applied to other large scale spreading problems, such as the world-wide epidemic control.
The influence of maturation on functional performance and injury markers in male youth

Abstract The aim of this study was to identify the influence of maturation on sprinting and jump performances, whilst quantifying injury markers in 95 youth males (age 13.2–15.7y). Comparative statistics were performed between maturation groups, identifying significant differences (p < 0.05) in all measured anthropometric variables. Sprint and jump performances were positively influenced (ES = trivial to large) by maturation status, whereas injury markers revealed no significant differences between groups. Increases in limb length, muscle size and muscular force output due to corresponding neuromuscular maturation, may help account for these improvements. Individuals’ within the circa PHV group exhibit a larger variability in sprint and jump performance when compared to the pre or post maturation groups. This variability may be attributed to the under-researched phenomenon of “adolescent awkwardness”. To conclude, performance characteristics of youth of similar chronological age vary considerably based on biological maturation, which may have consequences for long-term athlete development.
Irradiation-Related Lymphopenia for Bone Metastasis from Hepatocellular Carcinoma

Background/Aim: In the era of immunotherapy, treatment-related lymphopenia (TRL) is gaining attention. In this study, TRL was investigated in patients with bone metastasis from hepatocellular carcinoma (HCC) treated with radiotherapy (RT). Methods: Clinical data of 302 patients receiving RT for 511 bone metastases from HCC between 2005 and 2018 were reviewed. Data on absolute lymphocyte count (ALC) from pre-RT to 12 months post-RT were collected. Severe TRL was defined as ALC <500 cells/mm3 and evaluated using ALC 2 months after initiating RT. Factors associated with TRL were analyzed, which include the amount of active bone marrow within the RT field. The amount of active bone marrow included in the RT field was calculated as the product of the percentage of the bone compartment included in the RT field and the active bone marrow percentage of the bone compartment. Results: Overall, 33.4% of patients developed TRL 2 months after initiating RT. The mean ALC decreased after initiating RT and remained persistently low during 12 months of observation. Overall survival (OS) was significantly worse in patients with TRL than in those without (median OS: 3.7 vs. 6.5 months, p < 0.001). In the prognostic factor analysis, TRL was an independent prognostic factor of OS (p = 0.036), along with known prognostic factors of HCC. The percentage of active bone marrow within the RT field was the only significant factor associated with TRL (p < 0.001). Conclusion: TRL was observed in patients receiving RT for bone metastasis from HCC, and it was associated with poor survival. The percentage of active bone marrow within the RT field significantly affected TRL development. The results suggest that a new strategy is required to prevent TRL.
Evaluation of Survival Rate and Non-Fetal Outcomes in Patients with Esophageal Cancer Under Treatment with Neoadjuvant Chemoradiotherapy Plus Additional Platinium-Based Chemotherapy from 2010 to 2016

Background: Esophageal cancer is an invasive lethal disease with a 10-year survival rate since diagnosis. About 45% of the tumor is completely removed by surgery, which has 5% mortality and 20% survival rate. In the locoregional stage, the use of neoadjuvant chemoradiotherapy and then surgery reduces recurrence and increases survival. Objectives: Thisstudywasperformedtoinvestigatetheeﬀectof neoadjuvantchemoradiotherapyandthesubsequentchemother-apy with platinum-based regimen on survival, recurrence, and response to treatment. Methods: Planning a descriptive retrospective follow-up study, during 2010 to 2016, 44 patients with esophageal cancer, who received chemotherapy with 5-Fluorouracil + Oxaliplatin + Docetaxel before and after radiotherapy (45 - 50 Gray) accompanying by oral Capecitabin, were followed up. Five operable patients underwent surgery. Response to treatment and recurrence were evalu-atedbyperiodicendoscopicbiopsyandimaging. Tocalculatetheresponseratetotreatment,survival,andrecurrence,thedatawere extracted and analyzed, using SPSS version 18. The categorized variables were compared, using Pearson’s test. The survival curves were drawn, using the Kaplan Meier method and compared with the log-rank test. Results: Among44patientswithanaverageageof 61.5 ± 11.5years,88.6% hadsquamouscellcarcinoma(SCC)and11.4% hadadeno-carcinoma; surgery was performed for 5 patients, one of whom had severe complication leading to death and 54.5% had complete response as well as more survival rate. The patients suﬀering from SCC and middle segment tumors had more response rate. Also, recurrence was seen in 16 patients (36.4%), of whom 9.1% had local recurrence and 27.3% had metastatic recurrence. The mean survival rate was 38.87 months and 1-, 3-, and 5-year survival rate was %81.6, %47.6, and 39.6%, respectively. It was signiﬁcantly more in middle esophageal segment and also tumors with complete response to treatment. Conclusions: Regardingtheresults,thistreatmentapproachincreasesoverallanddisease-freesurvival,andresponsetotreatment and reduces locoregional recurrence even if no surgery is performed. This treatment is recommended as a deﬁnitive treatment for esophageal cancer without metastasis. can be seen, the treatment applied in our study increased the complete pathologic survival of complete
Teacher Scaffolding in Small-Group Work: An Intervention Study

Adapting support contingently to student needs by first diagnosing their current understanding, that is, scaffolding, is considered a key aspect of excellent teaching. The use of classroom scaffolding is rare, however. We therefore investigated the benefits to teachers of a professional development program that was based upon a model of contingent teaching (MCT) with the following 4 steps: diagnostic strategies, checking of diagnoses, giving contingent support, and checking of student learning. In our experimental study, 17 of 30 teachers participated in this program. All of the teachers (prevocational education; teaching social studies) taught the same 5-lesson project on the European Union. The frequency and quality of their use of the 4 steps from the MCT were then compared. The teachers who worked with the MCT increased their teaching quality more than the teachers who did not participate, especially with regard to the steps of contingent teaching. They also showed more complete cycles of contingent teaching at postmeasurement than the other teachers. Less successful teachers showed a tendency to provide less support because they mistakenly thought that prompting was not part of scaffolding. Future scaffolding research and professional development efforts aimed at promoting scaffolding can benefit from the MCT, provided that teachers’ understanding of scaffolding is closely monitored.
Risk Factors in Descending Necrotizing Mediastinitis Following Submandibular Abscess at dr. Cipto Mangunkusumo Hospital in Januari 2012 – Juli 2016

Introduction . Descending necrotizing mediastinitis (DNM) encountered problem of a high mortality rate. The increasing number of incidence and the need of immediate intervention DNM cases urge surgeons to manage early preventions dan adequate therapy. The purpose of this study is to find risk factors that correlate to the incidence of DNM in submandibular abscess patients. Method . Cross sectional study conducted enrolling all patients diagnosed with submandibular abscess that developed to DNM and treated surgically in emergency operating theater in period of January 2012 to July 2016 were reviewed. Mediastinitis which was not following submandibular abscess, those were not treated surgically or treated by other than the division of thoracic and cardiovascular surgery, and those of pediatrics were not included on the study. The incidence of DNM was the dependent variable on the study; risk factors such as gender, age, body mass index (BMI), comorbid(s), leukocyte counts, and microorganism(s) were independent variables on the study. Results. There were 68 subjects enrolled on the study. The met the inclusion and exclusion criteria. Subjects characteristics are shown in table 1. Septic condition, surgical intervention, postoperative complications, and mortality are shown in table 2. There was no correlation between gender (p = 0.656), age (p = 0.763), comorbid(s) (p = 0.767 and 0.952). It also found that leukocyte counts, and cultured microorganism(s) showed no significant correlation. Conclusion . Not a single risk factor specifically correlate to the incidence of DNM in subjects with submandibular abscess. Thus, so those with submandibular abscess have a same risk to have DNM developed. Keywords : descending necrotizing mediastinitis, submandibular abscess, risk factors
Sex differences in lower extremity musculoskeletal and neuromuscular characteristics in intercollegiate soccer athletes

ABSTRACT Purpose: Establishing sex-specific musculoskeletal characteristics promotes specific and effective injury prevention. The purpose was to identify sex differences in musculoskeletal characteristics in soccer athletes.Methods: 80 collegiate male and female soccer athletes participated. Flexibility included: weight-bearing ankle dorsiflexion mobility (DFM), active ankle dorsiflexion (ADF), active knee extension (AKE), and passive hip flexion (PHF). Strength tests included: ankle dorsiflexion/inversion/eversion, knee flexion/extension, hip abduction/adduction/internal/external rotation. LE dynamic postural stability (DPS) was assessed with an accelerometer. DPS was expressed as the Dynamic Postural Stability Index composite (DPSIC) and component scores in the anterior/posterior (APSI), medial/lateral (MLSI), and vertical (VSI) directions. If normally distributed, differences were calculated using a Student’s T-test; if non-normal, a Mann–Whitney U test was utilized.Results: Flexibility tests yielded significant differences for AKE (Dominant:p = 0.008, Non-Dominant:p = 0.040) and PHF (Dominant:p < 0.000,Non-Dominant:p = 0.001). Strength tests yielded significant differences for non-dominant hip internal rotation (p = 0.002). Dynamic postural stability tests yielded significant differences for DPSIC (p = 0.0160) and APSI (p = 0.014). Conclusion: These results implicate that flexibility and DPS may be better linked to sex than strength, suggesting that they may sex-specific musculoskeletal characteristics for the purpose of effective injury prevention.
Development of a Sense and Avoid System

Remotely Operated Aircraft (ROAs) currently do not have convenient access to civil airspace due to their inability to provide an onboard capability to “see and avoid” air traffic. Defense Research Associates, Inc. and AFRL/SNJT have developed affordable technology based on silicon charge couple device sensors and passive moving target detection algorithms. Previously, a flight demonstration proved real-time implementation of complex detection and tracking algorithms with multiple sensors providing a wide field of regard was feasible. This paper documents lessons learned from that demonstration, subsequent improvements made to the prototype system, resulting performance improvements, and planned next steps .