Miracle-dz/UniFAR-FTUs huggingface dataset:
Selective discrete Fourier transform algorithm for time-frequency analysis: method and application on simulated and cardiovascular signals

The Selective Discrete Fourier transform (DFT) Algorithm [SDA] method for the calculation and display of time-frequency distribution has been developed and validated. For each time and frequency, the algorithm selects the shortest required trace length and calculates the corresponding spectral component by means of DFT. This approach can be extended to any cardiovascular related signal and provides time-dependent power spectra which are intuitively easy to consider, due to their close relation to the classical spectral analysis approach. The optimal parameters of the SDA for cardiovascular-like signals were chosen. The SDA perform standard spectral analysis on stationary simulated signals as well as reliably detect abrupt changes in the frequency content of nonstationary signals. The SDA applied during a stimulated respiration experiment, accurately; detected the changes in the frequency location and amplitude of the respiratory peak in the heart rate (HR) spectrum. It also detected and quantified the expected increase in vagal tone during vagal stimuli. Furthermore, the HR time-dependent power spectrum displayed the increase in sympathetic activity and the vagal withdrawal on standing. Such transient changes in HR control would have been smeared out by standard heart rate variability (HRV), which requires consideration of long trace lengths. The SDA provides a reliable tool for the evaluation and quantification of the control exerted by the Central Nervous System, during clinical and experimental procedures resulting in nonstationary signals.
Stability of Psychiatric Diagnoses in Clinical Practice

This is a retrospective study that aimed at studying the diagnostic stability of psychiatric diagnoses over a 4-year period. Three-hundred and twelve patients (n=312) admitted more than once to Al Ain in-patient unit from January 1, 1990 to December 31, 1993, were the subjects for this study. The sample included patients with the following index diagnoses: acute psychoses (n = 37), alcohol abuse (n = 15), bipolar disorder (n = 27), depressive disorders (n = 63), drug abuse (n = 21), hysteria (n = 23), neurotic disorders (n = 50) and schizophrenia (n = 76). Diagnoses on discharge for first admissions were considered the index diagnoses. The shift from index diagnoses to subsequent diagnoses was counted. Diagnostic stability was calculated as the percentages of index diagnoses that did not change over time. In nearly half of the patients the index diagnoses changed over the 4-year period. Highest diagnostic stability was found in patients with index diagnoses of alcohol abuse, schizophrenia and drug abuse (92%, 74% and 71 % respectively), while the lowest stability was found in patients with neurotic, hysterical, depressive disorders, acute psychoses and bipolar disorders (38%, 48% and 45%, 42%, 52% respectively). Two distinct patterns of shifts were noted. First shift occurred between functional psychoses and second shift between depressive and neurotic disorders. This study provides further support to the notion that diagnostic stability in clinical practice is still far from being satisfactory.
Documenting individual identity : the development of state practices in the modern world

Acknowledgments ix Introduction: Jane Caplan and John Torpey 1 PART ONE: CREATING APPARATUSES OF IDENTIFICATION 13 1. Describing the Person, Reading the Signs in Late Medieval and Renaissance Europe: Identity Papers, Veste Figures, and the Limits of Identification, 1400-1600 by Valentin Groebner 15 2. The Identification of the Citizen: The Birth of Republican Civil Status in France by Gerard Noiriel 28 3. "This or That Particular Person": Protocols of Identification in Nineteenth-Century Europe by Jane Caplan 49 4. Making Social Groups, One Person at a Time: The Identification of Individuals by Estate, Religious Confession, an Ethnicity in Late Imperial Russia by Charles Steinwedel 67 5. Colonizing the Subject: The Genealogy an Legacy of the Soviet Internal Passport by Marc Garcelon 83 6. Modern Horrors: British Identity and Identity Cards by Jon Agar 101 PART TWO: IDENTIFICATION RACTICES AND POLICING 121 7. Republican Identity: Bertillonage as Government Technique by Martine Kaluszynski 123 8. The Standardize Gaze: The Standardization of the Search Warrant in Nineteenth-Century Germany by Peter Becker 139 9. Anthropometry, the Police Expert, an the Deptford Murders: The Contested Introduction of Fingerprinting for the Identification of Criminals in Late Victorian an Edwardian Britain by Anne M. Joseph 164 10. Fingerprinting an the Argentine lan for Universal Identification in the Late Nineteenth an Early Twentieth Centuries by Kristin Ruggiero 184 PART THREE: IDENTIFICATION AND CONTROL OF MOVEMENT 197 11. Domenica Saba Takes to the Road: Origins an Development of a Modern Passport System in Lombardy-Veneto by Andrea Geselle 199 12. Governments and Forgers: Passports in Nineteenth-Century Europe by Andreas Fahrmeir 218 13. A Many-Headed Monster: The Evolution of the Passport System in the Netherlands an Germany in the Long Nineteenth Century by Leo Lucassen 235 14. The Great War an the Birth of the Modern Passport System by John Torpey 256 PART FOUR: CONTEMPORARY ISSUES IN IDENTIFICATION 271 15. DNA-Typing: Galton's Eugenic Dream Realized? by Pamela Sankar 273 16. Under My Skin: From Identification Papers to Body Surveillance by David Lyon 291 17. Identity an Anonymity: Some Conceptual Distinctions and Issues for Research by Gary T. Marx 311 18. Identifiying Unauthorize Foreign Workers in the German Labor Market by Dita Vogel 328 19. Identity Cards, Ethnic Self-Perception, and Genocide in Rwanda by Timothy Longman 345 Bibliography 359 Notes on Contributors 397 Index 403
Genetic education for primary care providers: improving attitudes, knowledge, and confidence.

OBJECTIVE To increase primary care providers' awareness and use of genetic services; increase their knowledge of genetic issues; increase their confidence in core genetic competencies; change their attitudes toward genetic testing for hereditary diseases; and increase their confidence as primary care genetic resources. DESIGN Participants completed a workshop and 3 questionnaires: a baseline questionnaire, a survey that provided immediate feedback on the workshop itself, and a follow-up questionnaire 6 months later. SETTING Ontario. PARTICIPANTS Primary care providers suggested by deans of nursing, midwifery, family medicine, and obstetric programs, as well as coordinators of nurse practitioner programs, in Ontario and by the Ontario College of Family Physicians. INTERVENTION A complex educational intervention was developed, including an interactive workshop and PowerPoint educational modules on genetic topics for participants' use (available at www.mtsinai.on.ca/FamMedGen/). MAIN OUTCOME MEASURES Awareness and use of genetic services, knowledge of genetics, confidence in core clinical genetic skills, attitudes toward genetic testing, and teaching activities related to genetics. RESULTS The workshop was attended by 29 participants; of those, 21 completed the baseline questionnaire and the 6-month follow-up questionnaire. There was no significant change found in awareness or reported use of genetic services. There was significant improvement in self-assessed knowledge of (P = .001) and confidence in (P = .005) skills related to adult-onset genetic disorders. There were significant increases in confidence in many core genetic competencies, including assessing risk of hereditary disorders (P = .033), deciding who should be offered referral for genetic counseling (P = .003), discussing prenatal testing options (P = .034), discussing benefits, risks, and limitations of genetic testing (P = .033), and describing what to expect at a genetic counseling session (P = .022). There was a significant increase in the number of primary care providers agreeing that genetic testing was beneficial in the management of adult-onset diseases (P = .031) and in their confidence in being primary care genetic resources for adult-onset genetic disorders (P = .006). CONCLUSION Educational interventions that include interactive peer resource workshops and educational modules can increase knowledge of and confidence in the core competencies needed for the delivery of genetic services in primary care.
Characterization of Rhodobacter capsulatus genes encoding a molybdenum transport system and putative molybdenum-pterin-binding proteins

The alternative, heterometal-free nitrogenase of Rhodobacter capsulatus is repressed by traces of molybdenum in the medium. Strains carrying mutations located downstream of nifB copy II were able to express the alternative nitrogenase even in the presence of high molybdate concentrations. DNA sequence analysis of a 5.5-kb fragment of this region revealed six open reading frames, designated modABCD, mopA, and mopB. The gene products of modB and modC are homologous to ChlJ and ChlD of Escherichia coli and represent an integral membrane protein and an ATP-binding protein typical of high-affinity transport systems, respectively. ModA and ModD exhibited no homology to known proteins, but a leader peptide characteristic of proteins cleaved during export to the periplasm is present in ModA, indicating that ModA might be a periplasmic molybdate-binding protein. The MopA and MopB proteins showed a high degree of amino acid sequence homology to each other. Both proteins contained a tandem repeat of a domain encompassing 70 amino acid residues, which had significant sequence similarity to low-molecular-weight molybdenum-pterin-binding proteins from Clostridium pasteurianum. Compared with that for the parental nifHDK deletion strain, the molybdenum concentrations necessary to repress the alternative nitrogenase were increased 4-fold in a modD mutant and 500-fold in modA, modB, and modC mutants. No significant inhibition of the heterometal-free nitrogenase by molybdate was observed for mopA mopB double mutants. The uptake of molybdenum by mod and mop mutants was estimated by measuring the activity of the conventional molybdenum-containing nitrogenase. Molybdenum transport was not affected in a mopA mopB double mutant, whereas strains carrying lesions in the binding-protein-dependent transport system were impaired in molybdenum uptake.
Generation of Recombinant Human Parainfluenza Virus Type 1 Vaccine Candidates by Importation of Temperature-Sensitive and Attenuating Mutations from Heterologous Paramyxoviruses

ABSTRACT Human parainfluenza virus type 1 (HPIV1) is a significant cause of respiratory tract disease in infants and young children for which a vaccine is needed. In the present study, we sought to attenuate HPIV1 by the importation of one or more known attenuating point mutations from heterologous paramyxoviruses into homologous sites in HPIV1. The introduced mutations were derived from three attenuated paramyxoviruses: (i) HPIV3cp45, a live-attenuated HPIV3 vaccine candidate containing multiple attenuating mutations; (ii) the respiratory syncytial virus cpts530 with an attenuating mutation in the L polymerase protein; and (iii) a murine PIV1 (MPIV1) attenuated by a mutation in the accessory C protein. Recombinant HPIV1 (rHPIV1) mutants bearing a single imported mutation in C, any of three different mutations in L, or a pair of mutations in F exhibited a 100-fold or greater reduction in replication in the upper or lower respiratory tract of hamsters. Both temperature-sensitive (ts) (mutations in the L and F proteins) and non-ts (the mutation in the C protein) attenuating mutations were identified. rHPIV1 mutants containing a combination of mutations in L were generated that were more attenuated than viruses bearing the individual mutations, showing that the systematic accretion of mutations can yield progressive increases in attenuation. Hamsters immunized with rHPIV1 mutants bearing one or two mutations developed neutralizing antibodies and were resistant to challenge with wild-type HPIV1. Thus, importation of attenuating mutations from heterologous viruses is an effective means for rapidly identifying mutations that attenuate HPIV1 and for generating live-attenuated HPIV1 vaccine candidates.
Tobacco and alcohol during pregnancy: prevalence and determinants in Geneva in 2008.

OBJECTIVES To describe alcohol and tobacco consumption during pregnancy in women giving birth in a public hospital in Geneva, to evaluate risk factors related to these consumptions and to explore the influence of close relatives on the consumption habits of pregnant women. METHODS A cross-sectional questionnaire survey after delivery in 207 women in the maternity ward of the Geneva University Hospitals in 2008. We used retrospective self-reports of smoking during pregnancy (including temporary smoking), smoking during the entire pregnancy and alcohol drinking during pregnancy (even a single glass). RESULTS The proportion of smokers decreased from 31.2% before pregnancy to 21.7% during pregnancy (temporary smoking included), and 9.2% of women smoked continuously until delivery. Major factors associated with tobacco use were living alone, living with a smoker and tobacco consumption of the husband/partner in the presence of the pregnant woman. Regarding alcohol consumption, 62.7% of the participants reported drinking (even occasionally) before pregnancy, and 36.3% of the women drank at least one glass of alcohol during pregnancy. The alcohol consumption of the husband/partner and invitations to drink from other people were associated with alcohol consumption during pregnancy. CONCLUSIONS Among women delivering in a public hospital, tobacco and alcohol consumption during pregnancy was important and significantly influenced by the habits and attitude of close relatives. The involvement of relatives in health promotion interventions should be addressed.
Potential Ecological and Human Health Impacts of Antibiotics and Antibiotic-Resistant Bacteria from Wastewater Treatment Plants

The occurrence of antibiotics and other pharmaceuticals in the environment has become an increasing public concern as recent environmental monitoring activities reveal the presence of a broad range of persistent pharmaceuticals in soil and water. Studies show that municipal wastewater treatment plants (WWTPs) are important point sources of antibiotics and antibiotic-resistant bacteria in the environment. The fate of antibiotics and other pharmaceuticals in WWTPs is greatly influenced by the design and operation of treatment systems. Because knowledge on the fate of antibiotics and resistant bacteria in WWTPs is important in estimating their potential impacts on ecology and human health, investigations on occurrence, treatment, and observed effects are reviewed in this article. In addition, human health risk assessment protocols for antibiotic and resistant bacteria are described. Although data on other pharmaceutical compounds are also presented, discussion is focused on antibiotics in the environment because of the potential link to increased emergence of resistance among pathogenic bacteria. The applications of modern analytical methods that facilitate the identification of novel transformation products of pharmaceuticals in environmental matrices are also included to illustrate that the disappearance of the parent pharmaceuticals in WWTPs does not necessarily equate to their complete removal.
GPGPU: general purpose computation on graphics hardware

The graphics processor (GPU) on today's commodity video cards has evolved into an extremely powerful and flexible processor. The latest graphics architectures provide tremendous memory bandwidth and computational horsepower, with fully programmable vertex and pixel processing units that support vector operations up to full IEEE floating point precision. High level languages have emerged for graphics hardware, making this computational power accessible. Architecturally, GPUs are highly parallel streaming processors optimized for vector operations, with both MIMD (vertex) and SIMD (pixel) pipelines. Not surprisingly, these processors are capable of general-purpose computation beyond the graphics applications for which they were designed. Researchers have found that exploiting the GPU can accelerate some problems by over an order of magnitude over the CPU.However, significant barriers still exist for the developer who wishes to use the inexpensive power of commodity graphics hardware, whether for in-game simulation of physics of for conventional computational science. These chips are designed for and driven by video game development; the programming model is unusual, the programming environment is tightly constrained, and the underlying architectures are largely secret. The GPU developer must be an expert in computer graphics and its computational idioms to make effective use of the hardware, and still pitfalls abound. This course provides a detailed introduction to general purpose computation on graphics hardware (GPGPU). We emphasize core computational building blocks, ranging from linear algebra to database queries, and review the tools, perils, and tricks of the trade in GPU programming. Finally we present some interesting and important case studies on general-purpose applications of graphics hardware.The course presenters are experts on general-purpose GPU computation from academia and industry, and have presented papers and tutorials on the topic at SIGGRAPH, Graphics Hardware, Game Developers Conference, and elsewhere.
A compact LTCC Transmit Receive module at Ku-band

A 15–17GHz Transmit Receive module is developed using Ferro A6M LTCC multilayer substrate. The T/R module consists of a core RF T/R module and a down converter. Three types of T/R architecture are discussed and a T/R architecture based on system requirement is proposed. For the feasibility of the T/R module, each component is designed individually. Three key components, which are low noise amplifier, power amplifier and bandpass filter, are presented in this paper in detail. The measured low noise amplifier has a 20dB gain, a −7dB return loss and a 2.6dB noise figure from 8 GHz to 20 GHz. From 15 GHz to 17 GHz, the gain is greater than 21dB with ±0.5dB variation, the noise figure is less than 2.5dB, the input return loss is smaller than −7dB and the output return loss is less than −9dB. The power amplifier shows a measured gain of 30.4dB with ± 0.5dB variation in 15–17GHz and a 1dB compression output power of 28.2dBm at 16GHz. The input return loss is better than −10dB and the output return loss is better than −8dB. The measured filter has a maximum in-band insertion loss of −2.8dB, a return loss of −15dB and out-band rejection of −40dB@DC-12GHz and 20–28GHz. The compact T/R module has a size of 44×22× 1.1mm3. The measured results of the T/R module exhibit a transmit gain of 15dB, an output power of 26dBm and a receive gain of 35dB, a noise figure of 2.5~3.5dB.
A New Composite Facial and Scalp Transplantation Model in Rats

There are limited sources of autogenous tissue available for reconstruction of severe facial and scalp deformities caused by extensive tumor ablation, burns, or trauma. Allografts from cadaveric sources may serve as a reconstructive alternative. However, technical and immunological aspects of harvesting and transplanting face and scalp flaps limit the routine use of such procedures. For evaluation of the feasibility of composite-tissue reconstruction, an experimental model of composite face/scalp flap transplantation in rats was designed. Technical aspects of the model, survival rates, and the complications encountered during development of the model are presented. A total of 64 animals, in three experimental groups, were studied. In group I, the anatomical study group (n = 6), the anatomical features of the face and scalp region in rats were explored. Groups II and III were the transplantation groups. Isograft transplantations were performed between identical Lewis rats (RT11 to RT11), and allografts were transplanted, across major histocompatibility complex barriers, between Lewis-Brown Norway rats (RT1l/n) and Lewis rats (RT11). In group II (the control group, n = 8), transplantation of nonvascularized composite face/scalp isografts and allografts was performed. In group III (the transplantation group, n = 50), vascularized face/scalp isografts (n = 36) and allografts (n = 14) were transplanted. Complications included partial or total flap necrosis, death attributable to food aspiration, and poor general condition. To prevent acute and chronic allograft rejection, cyclosporine A (16 mg/kg per day) therapy was initiated 24 hours after transplantation; the dose was tapered to 2 mg/kg per day within 4 weeks and was maintained at that level thereafter. Long-term survival (>170 days) was achieved, without any signs of rejection, with low-dose (2 mg/kg per day) cyclosporine A therapy. This is the first report documenting successful composite face/scalp flap transplantation in the rat model.
Effects of In-Season Low-Volume High-Intensity Plyometric Training on Explosive Actions and Endurance of Young Soccer Players

Abstract Ramírez-Campillo, R, Meylan, C, Álvarez, C, Henríquez-Olguín, C, Martínez, C, Cañas-Jamett, R, Andrade, DC, and Izquierdo, M. Effects of in-season low-volume high-intensity plyometric training on explosive actions and endurance of young soccer players. J Strength Cond Res 28(5): 1335–1342, 2014—Integrating specific training methods to improve explosive actions and endurance in youth soccer is an essential part of players' development. This study investigated the efficiency of short-term vertical plyometric training program within soccer practice to improve both explosive actions and endurance in young soccer players. Seventy-six players were recruited and assigned either to a training group (TG; n = 38; 13.2 ± 1.8 years) or a control group (CG; n = 38; 13.2 ± 1.8 years) group. All players trained twice per week, but the TG followed a 7-week plyometric program implemented within soccer practice, whereas the CG followed regular practice. Twenty-meter sprint time (20-m), Illinois agility test time, countermovement jump (CMJ) height, 20- (RSI20) and 40- (RSI40) cm drop jump reactive strength index, multiple 5 bounds distance (MB5), maximal kicking test for distance (MKD), and 2.4-km time trial were measured before and after the 7-week period. Plyometric training induced significant (p ⩽ 0.05) and small to moderate standardized effect (SE) improvement in the CMJ (4.3%; SE = 0.20), RSI20 (22%; SE = 0.57), RSI40 (16%; SE = 0.37), MB5 (4.1%; SE = 0.28), Illinois agility test time (−3.5%, SE = −0.26), MKD (14%; SE = 0.53), 2.4-km time trial (−1.9%; SE = −0.27) performances but had a trivial and nonsignificant effect on 20-m sprint time (−0.4%; SE = −0.03). No significant improvements were found in the CG. An integrated vertical plyometric program within the regular soccer practice can substitute soccer drills to improve most explosive actions and endurance, but horizontal exercises should also be included to enhance sprinting performance.