Miracle-dz/UniFAR-FTUs huggingface dataset:
Prediction of underwater acoustic signals based on neural network

Local predictability is important in underwater acoustic signal processing,which is the basis in detection of non-stationary signals.Based on prediction of nonlinear time series and artificial neural networks,prediction of underwater acoustic signals is studied in this paper.Prediction models and design of network parameters are discussed.Predictions of both simulated data and real ship radiated noise data are made using BP and RBF network.Error distribution of the two kinds of network prediction models is obtained,and a method for effective reduction of prediction error is presented.The results are useful in the further study of underwater acoustic signal processing.
A radiomics nomogram for invasiveness prediction in lung adenocarcinoma manifesting as part-solid nodules with solid components smaller than 6 mm

Objective To investigate whether radiomics can help radiologists and thoracic surgeons accurately predict invasive adenocarcinoma (IAC) manifesting as part-solid nodules (PSNs) with solid components <6 mm and provide a basis for rational clinical decision-making. Materials and Methods In total, 1,210 patients (mean age ± standard deviation: 54.28 ± 11.38 years, 374 men and 836 women) from our hospital and another hospital with 1,248 PSNs pathologically diagnosed with adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA), or IAC were enrolled in this study. Among them, 1,050 cases from our hospital were randomly divided into a derivation set (n = 735) and an internal validation set (n = 315), 198 cases from another hospital were used for external validation. Each labeled nodule was segmented, and 105 radiomics features were extracted. Least absolute shrinkage and selection operator (LASSO) was used to calculate Rad-score and build the radiomics model. Multivariable logistic regression was conducted to identify the clinicoradiological predictors and establish the clinical-radiographic model. The combined model and predictive nomogram were developed based on identified clinicoradiological independent predictors and Rad-score using multivariable logistic regression analysis. The predictive performances of the three models were compared via receiver operating characteristic (ROC) curve analysis. Decision curve analysis (DCA) was performed on both the internal and external validation sets to evaluate the clinical utility of the nomogram. Results The radiomics model showed superior predictive performance than the clinical-radiographic model in both internal and external validation sets (Az values, 0.884 vs. 0.810, p = 0.001; 0.924 vs. 0.855, p < 0.001, respectively). The combined model showed comparable predictive performance to the radiomics model (Az values, 0.887 vs. 0.884, p = 0.398; 0.917 vs. 0.924, p = 0.271, respectively). The clinical application value of the nomogram developed based on the Rad-score, maximum diameter, and lesion shape was confirmed, and DCA demonstrated that application of the Rad-score would be beneficial for radiologists predicting invasive lesions. Conclusions Radiomics has the potential as an independent diagnostic tool to predict the invasiveness of PSNs with solid components <6 mm.
Health, school and family factors in adolescence and labour market integration problems in young adulthood : the HUNT study

AIMS: Family and intergenerational perspectives might contribute to a better understanding of why young people in many European countries experience work impairment and end up being dependent on public benefits for life sustenance. The aim of this cohort study was to explore the relationship between the receipt of medical benefits in parents and their young adult offspring and the contributions of family health and family socioeconomic status.METHODS: Baseline information on the health of 7597 adolescents and their parents who participated in the HUNT Study 1995-1997 was linked to national registers to identify long-term receipt of medical benefits for parents (1992-1997) and adolescents as they entered adulthood (1998-2008). We used logistic regression to explore the association between parent and offspring receipt of medical benefits, adjusting for family health and socioeconomic status.RESULTS: Among adolescents, 13% received medical benefits from age 20-29. Adolescents whose parents had received medical benefits (26%) were more likely to receive such benefits themselves from age 20-29 compared with adolescents without benefit-receiving parents (age- and sex-adjusted odds ratio (OR) 2.16, 95 % confidence interval (CI) 1.86-2.49). Adjustment for family health reduced this estimate considerably (to OR 1.66, 95% CI 1.38-1.99), whereas adjustment for family socioeconomic status had less impact.CONCLUSIONS: Adolescents whose parents receive medical benefits enter adult working life with an elevated risk of health-related work exclusion. Family health vulnerability appears to be a key to understanding this association, suggesting that more attention to intergenerational continuities of health could be a way to prevent welfare dependence in future generations.
The value of ultrasound grayscale ratio in the diagnosis of papillary thyroid microcarcinomas and benign micronodules in patients with Hashimoto’s thyroiditis: A two-center controlled study

Objective The value of ultrasound grayscale ratio (UGSR) in the diagnosis of papillary thyroid microcarcinomas (PTMCs) and benign micronodules (BMNs) has been recognized by some authors, but studies have not examined these aspects in patients with Hashimoto’s thyroiditis (HT). This retrospective study investigated the value of UGSR in the diagnosis of PTMCs and BMNs in patients with HT using data from two medical centers. Methods Ultrasound images of 428 PTMCs in 368 patients with HT and 225 BMNs in 181 patients with HT in center A were retrospectively analyzed and compared to the ultrasound images of 412 PTMCs in 324 patients with HT and 315 BMNs in 229 patients with HT in medical center B. All of the cases were surgically confirmed. The UGSR was calculated as the ratio of the grayscale value of lesions to the surrounding normal thyroid tissues. The optimal UGSR thresholds for the PTMCs and BMNs in patients with HT from the two medical centers were determined using a receiver operating characteristic (ROC) curve. Furthermore, other statistics, including the area under the curve (AUC), the optimal UGSR threshold, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy of the two medical centers, were pair analyzed in this study. Results The UGSR of PTMCs and BMNs in patients with HT from medical center A were 0.513 (0.442, 0.592) and 0.857 (0.677, 0.977) (Z = −15.564, p = 0), and those from medical center B were 0.514 (0.431, 0.625) and 0.917 (0.705, 1.131) (Z = −15.564, p = 0). For both medical centers A and B, the AUC, optimal UGSR threshold, sensitivity, specificity, PPV, NPV, and diagnostic accuracy of the UGSR in differentiating between PTMCs and BMNs in patients with HT were 0.870 and 0.889, 0.68 and 0.70, 0.921 and 0.898, 0.747 and 0.759, 0.874 and 0.829, 0.832 and 0.848, and 0.861 and 0.836, respectively. There were no significant differences in the UGSR for the PTMCs between patients from the two medical centers (Z = −0.815, p = 0.415), while there was a significant difference in the UGSR of the BMNs between patients from the two medical centers (Z = −3.637, p = 0). Conclusion In the context of HT, UGSR still has high sensitivity, accuracy, and stability in differentiating between PTMCs and BMNs, making it a complementary differentiator of thyroid imaging reporting and data systems. However, due to its low specificity, a comprehensive analysis of other ultrasound signs is required.
Multiteam Systems Handling Time-Sensitive Targets: Developing Situation Awareness in Distributed and Co-located Settings

There is an increasing interest in how to organize operations carried out by multiteam systems (MTS). Large MTS typically operate with a dedicated integration team, responsible for coordinating the operation. We report a study of a military multiteam system that prosecute time-sensitive targets. We asked whether and how the integration team’s efficiency depends on its communication setting. Specifically, we studied how a co-located vs. a distributed communications setting influenced the shared situation awareness and whether the shared situation awareness again influenced the outcome of the decision processes. We found that performance fell when the integration team shifted from a co-located to a distributed setting. The fall in performance seemed to be mediated by a corresponding fall in situation awareness. Moreover, while the performance improved for each run in the co-located setting, we did not see such learning in the distributed setting. Qualitative observations revealed that misunderstandings lasted longer in a distributed configuration than in a co-located setting. We found that situation awareness at level 3 was the only level of situation awareness significant for predicting all dimensions of performance. Implications for theory, research, and practice are discussed.
The Gypsy caravan : from real Roma to imaginary gypsies in Western music and film

Preface Acknowledgments Chapter One: The Relative Neglect of Gypsy Music: Nationalism, Interest, and Advocacy in Musicology Chapter Two: Alms, Virgins, and Feuerzeichen: Literature's Place in Configuring Gypsiness Chapter Three: A Nineteenth-Century Tale of Two Others: Gypsy Improvisation and the Exotic Remainder Chapter Four: Nomads and the Rhizome: Becoming Gypsy Chapter Five: Brahms's "Hungarian Dance no. 5" and the Dynamics of Exaggeration Chapter Six: The Poetics of Gypsiness in Liszt's Hungarian Rhapsodies Chapter Seven: Gypsies and Vol'nost' in Russian Music: Aleko Chapter Eight: Gypsy Pleroma: Janacek's Diary of One Who Disappeared Chapter Nine: The Specter of Bartok: From Hungarian Musicology to the Folk-Music Revival Chapter Ten: Gypsiness in Film Music: Spectacle and Act Chapter Eleven: O lunga drom: The Digital Migration of Gypsy Music Musical Examples Gypsy Music Discography References Index
The Persian and Carthaginian Invasions of 480 B.C.E. and the Beginning of the Classical Style: Part 2, the Finds from Other Sites in Athens, Attica, Elsewhere in Greece, and on Sicily; Part 3, the Severe Style: Motivations and Meaning

This study, in three parts, addresses the problem of the beginning of the classical style—the so-called Severe Style—from an archaeological perspective, focusing on those sculptures either found, or allegedly found, in Persian destruction contexts or directly associated with the Persian and Carthaginian invasions. Part 1 appears in a previous issue of the AJA (112 [2008] 377-412). Parts 2 and 3 are presented in this article. The first part of the study reexamined the 19th-century excavations of the Acropolis and demonstrated that the style probably did not predate the Persian invasion of 480-479 B.C.E. Part 2 revisits finds from elsewhere in Athens and Attica, Phokis, the Aphaia sanctuary on Aigina, and Sicily, with similar results. Part 3 summarizes current theories on the origins and significance of the Severe Style, suggests that the Tyrannicides of Kritios and Nesiotes, dedicated in 477/6, indeed inaugurated it, and reconsiders the idea that the Greek victories of 480-479 somehow inspired it, at least in part.
No-reference video quality assessment model based on artifact metrics for digital transmission applications

The main causes for the reducing of visual quality in digital imaging systems are the unwanted presence of degradations introduced during processing and transmission steps. However, measuring the quality of a video implies in a direct or indirect comparison between test video and reference video. In most applications, psycho-physical experiments with human subjects are the most reliable means of determining the quality of a video. Although more reliable, these methods are time consuming and difficult to incorporate into an automated quality control service. As an alternative, objective metrics, i.e. algorithms, are generally used to estimate video quality quality automatically. To develop an objective metric, it is important understand how the perceptual characteristics of a set of artifacts are related to their physical strengths and to the perceived annoyance. Then, to study the characteristics of different types of artifacts commonly found in compressed videos (i.e. blockiness, blurriness, and packet-loss) we performed six psychophysical experiments to independently measure the strength and overall annoyance of these artifact signals when presented alone or in combination. We analyzed the data from these experiments and proposed several models for the overall annoyance based on combinations of the perceptual strengths of the individual artifact signals and their interactions. Inspired by experimental results, we proposed a no-reference video quality metric based in several features extracted from the videos (e.g. DCT information, cross-correlation of sub-sampled images, average absolute differences between block image pixels, intensity variation between neighbouring pixels, and visual attention). A non-linear regression model using a support vector (SVR) technique is used to combine all features to obtain an overall quality estimate. Our metric performed better than the tested artifact metrics and for some full-reference metrics.
A cross-sectional study of practices regarding HIV/AIDS among attendees of integrated counseling and testing center at the SMS Medical College, Jaipur

Introduction: This proposed study was carried out among attendees of integrated counseling and testing center (ICTC) associated with the SMS Medical College, Jaipur which included general population as well as multiple types of high-risk behavior people to determine practices about the human immunodeficiency virus (HIV) and to correlate the socio-demographic profile of attendees with their practice about HIV/AIDS. Materials and Methods: This cross-sectional study was conducted among 177 attendees at ICTC at the SMS Medical College, Jaipur from May 2015 to October 2015. Data were collected through an anonymous pre-designed semi-structured questionnaire. Continuous variables were summarized as mean and standard deviation while categorical variables as proportion (%). Chi-square test was used for the analysis of categorical variable. Stepwise multiple logistic regression analysis was done to find out predictors of practice. All statistical calculations were done by using the Med Calc. 12.2. 1.0 software. Results: Most participants were male (80.79%), age group 20–29 year (44.07%), married (57.63%), Hindu (92.09%), from OBC caste (36.72%), graduate (22.6%), from urban setting (53.11%), joint family (66.67%), from socio-economic Class 1 (31.07%), and referred by doctor (61.02%). About 22% agreed that they had sexual intercourse with a person other than spouse; 8.47% agreed on having more than one sexual partner; 8.39% male respondents agreed that they had sex with men. Poor practice was prevalent in 16.38%. Gender, age, literacy, mode of referral, socio-economic class, and area of residence were found significantly associated (P < 0.05) with high-risk behavior. Literacy of respondents was found only significant predictor of practice scores in stepwise multivariate regression analysis with following regression equation – Practice score = 2.9821 + 0.3421 (Education). Conclusion: Literacy of respondents was found only significant predictor of practice scores. Government should strengthen IEC activities and ongoing HIV/AIDS education and prevention programs.
Elderly persons with acute pancreatitis – specifics of the clinical course of the disease

Background As may readily be inferred from clinical observations, there is an increasing prevalence of severe acute pancreatitis (SAP) in the elderly, even though the precise nature of the relationship between a patient’s age and severity of the disease has not been unequivocally determined to date. This study aimed therefore to investigate the incidence, clinical course, and mortality rate among the elderly patients suffering from acute pancreatitis (AP), as compared to younger ones. Methods A prospective study, lasting a single calendar year, covered patients with AP successively admitted to hospitals. The final assessment comprised 963 patients. The patients were subsequently divided into three groups corresponding to the three grades of disease severity, based on the Revised Atlanta Classification for Acute Pancreatitis. The actual cause of the disease, its clinical course, results of radiological ultrasonography, computed tomography, and laboratory tests, as well as the duration of hospital stay were assessed in due consideration of patients’ age (groups aged 65–79 years and ≥80 years vs <65 years). Results Cholelithiasis was determined as the main cause of AP among the older patients (54.08% and 58.12% vs 22.46%; P<0.000). Among the oldest patients (≥80 years), its course was often significantly more severe, in comparison with the ones under 65 years of age: 14.53% vs 6.31% (P<0.00); a phenomenon not observed in the age range 65–79 years, nor among the younger patients (7.69% vs 6.31%; P>0.05). Moderate AP occurred significantly more often in the younger patients compared to those aged ≥80 years (16% vs 8.55%; P<0.00), although without any significant differences observed between the group aged 65–79 years and the younger patients (13.27% vs 8.55%). SAP more frequently ended in death among the oldest patients – 11.97% vs 2.31% (P<0.000) than in the group aged 65–79 years (4.59%), as compared to the younger groups (P>0.05). Conclusion An appreciably higher susceptibility of older patients aged ≥80 years to AP, with cholelithiasis being the main cause that results in high mortality rate, is presently acknowledged a serious diagnostic and therapeutic management challenge to a national healthcare system.
Measuring cis-regulatory energetics in living cells using allelic manifolds

Gene expression in all organisms is controlled by cooperative interactions between DNA-bound transcription factors (TFs), but quantitatively measuring TF-DNA and TF-TF interactions remains difficult. Here we introduce a strategy for precisely measuring the Gibbs free energy of such interactions in living cells. This strategy centers on the measurement and modeling of “allelic manifolds”, a multidimensional generalization of the classical genetics concept of allelic series. Allelic manifolds are measured using reporter assays performed on strategically designed cis-regulatory sequences. Quantitative biophysical models are then fit to the resulting data. We used this strategy to study regulation by two Escherichia coli TFs, CRP and σ70 RNA polymerase. Doing so, we consistently obtained energetic measurements precise to ~ 0.1 kcal/mol. We also obtained multiple results that deviate from the prior literature. Our strategy is compatible with massively parallel reporter assays in both prokaryotes and eukaryotes, and should therefore be highly scalable and broadly applicable.
Evaluation of cardiac rehabilitation on functional capacity in depressed and nondepressed patients after angioplasty

Background: About 50% of the annual deaths in the developed countries are as a result of coronary artery disease. Several studies have shown the role of cardiac rehabilitation (CR) in improving cardiovascular indices including functional capacity, reducing depression, and mortality rates in cardiovascular patients. One of the psychological problems observed in cardiovascular patients is depression. Depression is one of the most important barriers to the treatment of heart attack, because it leads to denial of the disease and reduces the patient's motivation to continue treatment. Objectives: There are controversy information about the relationship between the effects of CR on these cases after angioplasty. The aim of this study was to evaluate the effect of CR on functional capacity in depressed and nondepressed patients after angioplasty in patients referred to Imam Khomeini, Ahvaz. Methods: This descriptive epidemiological study was performed on 54 patients referred for angioplasty. Functional capacity and depression score before and after participation in the 2-month CR program were evaluated in two groups of depressed and nondepressed patients. Data were analyzed by SPSS software, and the significance level was considered as P < 0.05. Results: The results of this study showed that in both the groups, the functional capacity after CR was significantly increased compared with the previous period (P < 0.001). Also in depressed patients, there was a significant decrease in depression scores (P < 0.001). Conclusion: Our findings showed improvement of functional capacity index following angioplasty, suggesting that patients participating in CR can be recommended by therapists. In addition, the results of this study showed that the participation in the CR program greatly affects the improvement of functional capacity and reduction in depression in patients undergoing angioplasty.
MDA-19 Suppresses Progression of Melanoma Via Inhibiting the PI3K/Akt Pathway

Abstract Objective To investigate the effect of MDA-19 on progression of melanoma, and explore the relevant mechanism. Methods The melanoma cell lines, M14 and UACC257, were treated with different concentrations of MDA-19, then CCK8, clone formation assay, Transwell and flow cytometry assays were performed to examine cell proliferation, migration, invasion and apoptosis, respectively. The expression of apoptosis-related proteins (Bcl-2, Bax and caspase 3 P17), EMT and signaling pathway-related proteins were also detected by Western blot. Results MDA-19 inhibited melanoma cells in a dose-dependent manner. Compared to the NC group, MDA-19 significantly inhibited cell growth capacity, migration and invasion of M14 and UACC257 cells, and accelerated cell apoptosis in a mitochondrial pathway through regulating Bcl-2/Bax and Caspase 3 in M14 and UACC257 cells. Moreover, MDA-19 was observed to up-regulate the expression of E-cad and down-regulate the expression of N-cad, Vimentin and Slug in melanoma cells in vitro. Furthermore, MDA-19 could inhibit the PI3K/Akt pathway by blocking Akt phosphorylation (p-Akt) and downstream proteins, P70 and Cyclin D1 in M14 and UACC257 cells. Conclusion Our data demonstrate that MDA-19 could inhibit progression of melanoma by suppressing the PI3K/Akt pathway, suggesting that MDA-19 is a potential anti-cancer agent for therapy of melanoma.