Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis of Drug Release from Different Agglomerates Using a Mathmatical Model

The release rate of an active ingredient from a dosage form may be affected by the agglomeration of an active ingredient before tablet compression. This study is aimed at establishing the effects of the agglomerates on active ingredient release profiles. A model substance, caffeine, was tested in the powdered form and in the two agglomerated forms prepared by wet granulation and compaction. The profiles of caffeine release from these forms were measured using a flow-through cell dissolution apparatus (USP 4) in an open-loop arrangement. To identify the particular processes responsible for the differences in the dissolution profiles of the model forms, we developed a mathematical description of the dissolution profiles. Using this mathematical approach, we proposed that caffeine was adsorbed to the microcrystalline cellulose present in the granulated and compacted form and that diffusion of the active ingredient was inhibited in the presence of a binder in the granulate. Both of these effects resulted in imperfections in the shape of dissolution profiles and in a decrease in the dissolution rate of caffeine. The mathematical model is based on generic parameters, thus it is transferable to other pharmaceutical substances in powdered and agglomerated forms.
Hematological Malignancies: Analysis of Myelogram Results over 21 Years in Lome Teaching Hospitals

Objectives: Determine the frequency of malignancies diagnosed in myelogram seen in hematology services of Campus and Sylvanus Olympio Teaching Hospitals in Lome from 1992 to 2013. Study the epidemiology profile of these diseases. Materials and methods: It was an analytical retrospective study of 469 cases of malignancies diagnosed in 1511 myelograms during 21 years in both teaching hospital of Lome. Results: Blood disorders represent 31.70% of the results of myelogram performed during 21 years in the Teaching Hospital of Lome. Each year, there is an average of 22.3 cases diagnosed hematological malignancies. The most hematological malignancies were Kahler's disease (28.57%), chronic myeloid leukemia (24.52%), chronic lymphocytic leukemia (22.17%), acute lymphoblastic leukemia (12.58%) and acute myeloid leukemia (8.10%). Other (4.05%) were represented by the essential hypereosinophilic syndrome (4 cases), hairy cell leukemia (4 cases), Sezary lymphoma (3 cases), essential thrombocythemia (3 cases), Waldenstrom's disease (2 cases), acute myelomonocytic leukemia (1 case), prolymphocytic leukemia (1 case) and plasma cell leukemia (1 case). By gender, the CLL is most predominant in women against CML in men. Hemopathies were observed at all ages of life. Conclusion: Hematological malignancies are diagnosed in the Teaching Hospital of Campus and Sylvanus Olympio in Lome with a high relatively frequency. This prevalence must be higher if all cases of malignancies diagnosed in Togo were recorded in a national cancer register. This study aims to knowledge of epidemiological aspects of hematological malignancies and improve the care of patients with hematological malignancies by the provision of adequate anti-mitotic drugs.
Reduction of speckle noise by using an adaptive window

Speckle noise is a multiplicative noise that results from random fluctuations of signals when they are reflected on a surface. This research article proposes a technique to reduce speckle noise by using classic statistical filters and a size-adaptive window. The advantage of using the mentioned window is that such filters show adequate performance at reducing noise and preserving edges. In fact, the results show that the measurement of absolute performance that can be obtained with this window is better than the best results when the window is not used. Such better performance is expressed in terms of the signal / noise ratio, the edge improvement index and the mean square error.
Acoustic correlates of stress in Besemah

The present study investigates the location and acoustic correlates of stress in Besemah, a Malay isolect of southwest Sumatra. While a number of studies have shown that other wellknown varieties of Malay do not show evidence of word-level stress, the present study is a first attempt at discovering whether Besemah shows evidence of word-level stress and if so what acoustic properties are associated with the stressed syllable. Results indicate that stress is realized on the ultima with a raised fundamental frequency, greater intensity, and longer duration. The study further investigates these results by looking at additional intonational evidence from naturalistic speech to better understand the interaction between word-level stress and phrase-level prominence. The present study adds to the current typology of prominence systems, demonstrating that Besemah is not on a par with other Malay varieties.
Divergent Views: Teacher and Professor Perceptions about Pre-College Factors that Influence College Science Success.

Interview data from secondary and postsecondary science instructors explored their in depth views on preparing students for college science. Professors expressed a high level of consensus concerning two factors: general student skills and mathematics preparation. Teachers, who expressed lower levels of consensus, did agree on the importance of mathematics, but also highlighted a variety of factors that promote active pedagogy in the classroom as well as the importance of technology, textbooks, other materials, and assessments. Given this divergence, the authors explored the research supporting the value of these factors as well as highlighted possible strategies for narrowing the gap. Introduction Transitioning from secondary to post-secondary educationis a daunting challenge for many students. Preparing them for this transition is an equally daunting task for their teachers. A recent report from Stanford University, Betraying the College Dream, points out that success in high school is a necessary yet insufficient step (Venezia, Kirst, & Antonio, 2003). The authors identify a serious disconnect between high school and college coursework and standards, and the lack of any system to facilitate a successful transition. In science education, the finding of a "disconnect" is not new. Studies conducted more than ten years ago reported important differences between the focus of high school teachers and expectations of college professors regarding student preparation (Razali & Yager, 1994; Shumba & Glass, 1994). It is increasingly important to re-address this transition because students, parents, and even high school teachers are unaware of what is expected of students entering college science. The risk is another generation of students entering college with insufficient science preparation to support their success and persistence. Adding to this concern is the decline in the average scores of high school seniors between 1996 and 2000, which may indicate that the preparation of high school seniors is declining rather than improving (National Science Board, 2006). Of more particular concern is the challenge the United States faces in maintaining its competitive edge in science research at the international level. The task of preparing future scientists for work in the US has become more difficult as the number of non-citizens in American universities and research institutions has decreased. Daunting visa restrictions for foreign scientists and science students have limited the pool of available researchers who can work in the US in recent years (Simoncelli & Stanley, 2005; Glanz, 2003). In addition, the National Science Foundation reports, "the number of native-born science and engineering (SE Shumba & Glass, 1994). Our study investigates how factors identified by both science instructors and the research literature impact student success in university science. …
Patch density determines movement patterns and foraging efficiency of large herbivores

Few experimental studies have tested theoretical predictions regarding the movement strategies of large herbivores and their consequences for foraging efficiency. We therefore analyze how the movement and foraging behavior of goats are related to patch density, with patches being trees and bushes. We show that their movements become slower and more tortuous when patch density increases, resulting in shorter steps, more acute turns, and a lower net displacement. Furthermore, the movements of the goats can be well described by Levy walks (LWs). In agreement with hypotheses generated by LW models, the goats move with μ a 2 at low patch density but with μ a 3 when patches are abundant. However, simplified statistical descriptors of movement patterns like the shape of the step/flight length and turn angle distributions become insufficient in predicting foraging efficiency when patch density is high because then the sequence of steps and turns becomes an important determinant of foraging efficiency. By changing their movements and behavior with increasing patch density, the goats intensify their utilization of resources and consequently are able to raise the efficiency of the foraging process more than proportional to the increase in patch density. This resembles the concept of area-restricted search, stating that animals concentrate their foraging effort in areas with high reward, thereby increasing the efficiency of foraging. The findings as presented in this paper provide support for theoretical expectations on the movement and foraging behavior of large herbivores in relation to resource density. Copyright 2007, Oxford University Press.
Determination of antioxidant activity and t otal phenol contents of two Salvia extracts

The most Salvia species are used as a traditional herbal tea in some Mediterranean countries. It has been collected from their natural habitat. Total phenolic substance, flavonol amounts, antioxidant capacity and antiradical activity values of sage extracts were determined as 51.19-118.13 mg Gallic Acid Equivalent (GAE)/gm, 820.71-1000.65 µg RE/gm, 67.26 to 138.44 mg AAE, and 725.19 – 815.56 IC50 = µg/ml, respectively. In medicinal sage (Salvia fruiticosa), the highest total phenolic total flavonol, antiradical activity and antioxidant capacity were found in U2 (Metanol:water:acetic acid (95:4.5:0.5)), U2, U3 (Aceton:water:acetic acid (95:4.5:0.5)) and S1 extracts, respectively. In addition, total phenol and total flavonol of sage extract were found in U5. Antiradical activity values of extracts of S.fruticosa changed between 599.10 µg/m and 890.14 µg/ml. The obtained results recommended that sage could be regarded as an important source of natural antioxidant.
Molecular Detection Based Epidemiology of Canine Parvovirus and Canine Coronavirus Infection in Diarrheic Dogs in Haryana

Diarrheic faecal samples of dogs were screened for the presence of canine parvovirus (CPV) and canine coronavirus (CCoV) using polymerase chain reaction (PCR) and reverse transcriptase polymerase chain reaction (RT-PCR) respectively followed by analysis of positive cases to find their relationship with breed, age, sex and vaccination status. Faecal samples were collected from dogs having vomition and diahorrea. PCR amplification of DNA and RNA (c-DNA) templates extracted from the faecal samples was conducted using the designed primers against the relevant genes (VP2 and M) of the two viruses respectively. Out of a total 50 screened faecal samples, twenty five were found positive for CPV and 4 samples for CCoV infection by developed PCR/RT-PCR. Out of 25 CPV positive dogs, 23 dogs were from Hisar district and one dog each was reported from Fatehabad and Jind district of Haryana. Out of four positive CCoV dogs one dog was reported from Fatehabad and three other were reported from Hisar. The disease was found to be more common in mixed breed, male pups of less than 6 months of age. The percent prevalence of positive cases in unvaccinated or inadequately vaccinated dogs was found to be 96.55%. PCR and RT-PCR based detection revealed 50% and 8% prevalence of CPV and CCoV respectively. It may be concluded that CPV and CCoV infections are very much prevalent in the state and their prevalence is very high in dogs not vaccinated. Thus, there is a need to strengthen vaccination against these etiological agents.
The Forecasting Power of the Volatility Index in Emerging Markets: Evidence from the Taiwan Stock Market

This paper explores the predictive power of the volatility index (VIX) in emerging markets from December 2006 to March 2010. The results of the study show that the models including both the volatility indicator and the option market information have a stronger predictive power. The predictive power of the models is improved by 88% in explaining the future volatility of stock markets, much better than that of other models merely considering the volatility indicator. With respect to the trading information from different types of investors in option markets, the trading information from the foreign institutional investors in option markets demonstrates a significantly positive relationship with the stock market volatility. In addition, the results of this paper also reveal that the volatility index (TVIX) of Taiwan stock index options is a strong indicator of future stock market volatility. The TVIX outperforms the historical volatility and the GARCH volatility forecast in assessing the activities of Taiwan’s stock market.
Understanding and Treating Perfectionism in Frum Adolescents

A motor device including a pair of motor units and a driven member meshed with rotary gears of the pair of motor units to drive the driven member, the motor units each including a rotary magnet that is cylindrical and magnetized so as to have different magnetic poles in turn along the circumferential direction, a rotary gear having a plurality of teeth, the rotary gear rotating about the rotation axis of the rotary magnet together with the rotary magnet, and a stator member having a plurality of outer magnetic poles that are arranged on the outer periphery of the rotary magnet and an inner magnetic pole that is arranged on the inner periphery of the rotary magnet and is opposed to the outer magnetic poles, the plural outer magnetic poles and the inner magnetic pole being excited by a coil.
Oxytocin and Pareidolia Face Detection Using the Visual Search Task. A double blind, placebo-controlled within-subject design study using eye tracking and intranasal oxytocin.

Face pareidolia is the human tendency to see illusory human-like faces, for example in random patterns exhibiting configural properties of a face. Past research on humans’ show that oxytocin has a crucial role in enhancing facial processing. By leading to an increased focus on the face in general, and eyes especially, alter the encoding and conceptual recognition of social stimuli, enhancing sensitivity to ‘hidden’ emotions in facial expressions, and enhancing the ability to interpret the facial cues of others, oxytocin has been proposed to promote prosocial behavior in humans. In this study, we evaluated whether oxytocin modified responses to illusory face perception at an earlier perceptual, bottom-up stage of processing during limited time in the visual search task. In a double blind, randomized, placebocontrolled, within-subject design, oxytocin (24 IU) and placebo was administered to 24 healthy volunteers in two different sessions. Results revealed that random elements were perceived as a face when organized together within a configural facial distance, showing that illusory facial elements both attract pre-attentive attention resources and stands out from background of other objects and natural elements. Random elements presented in a scrambled fashion were not perceived as faces. Oxytocin did not, however, influence the accuracy of detecting pareidolia compared to placebo. Neither response time, nor confidence, gaze toward illusory faces or eyes were enhanced by the neuropeptide. The results of this study suggest that oxytocin may not influence the detection of illusory faces at early perceptual levels of processing. On the other hand, oxytocin may prove to have greater influence in altering the cognitive processing of social valence at more conceptual and elaborate levels of processing.
Three-dimensional numerical simulation of blood flow in two coronary stent

The aim of the present study is to carry out Computational Fluid Dynamics simulations in a realistic three dimensional geometry of two stent under physiological conditions. The two stent, similar to real coronary ones, are both made of 12 rings but are differing as far as the position of the struts is concerned. One type has parallel-connectors and the other transverse-ones. The artery is modeled as rigid cylinder and the fluid is assumed as incompressible Newtonian fluid in laminar flow with the average physical properties of blood. The commercial computational fluid dynamic code FLUENT is used with the mesh made of non-uniform tetrahedrons. The mesh independence is proved using the steady state results of the wall shear stress. The parameters correlated to neo-intimal hyperplasia, such as wall shear stress, magnitude of wall shear stress gradient, and oscillatory shear index, are investigated. Time variation of the parameters is investigated with the conclusion that the stent with parallel-connectors has a better fluid dynamic behavior.
Phyllodes tumors of the breast: a retrospective evaluation of cases from the Hospital do Servidor Público Estadual de São Paulo

Study carried out at the Hospital do Servidor Público Estadual Francisco Morato de Oliveira – São Paulo (SP), Brazil. 1Hospital do Servidor Público Estadual Francisco Morato de Oliveira – São Paulo (SP), Brazil. 2Paulista School of Medicine, Universidade Federal de São Paulo – São Paulo (SP), Brazil. 3Instituto de Assistência Médica ao Servidor Público Estadual – São Paulo (SP), Brazil. *Corresponding author: matos.anabeatriz@gmail.com Conflict of interests: nothing to declare. Received on: 09/25/2017. Accepted on: 09/25/2017. Objetivo: Avaliar as características clínicas e patológicas do tumor filoides e identificar fatores relacionados com risco de recidivas em pacientes acompanhadas no ambulatório de Mastologia do Hospital do Servidor Público Estadual de São Paulo (HSPE-SP). Método: Estudo retrospectivo descritivo de dados de 52 pacientes, entre 1976 e 2013, dentre os quais: idade, tamanho do tumor, tipo histológico, margens cirúrgicas, tipo de cirurgia, recidivas e tempo para recidiva. Resultados: A idade média das pacientes foi 45,7 anos. O tamanho médio do tumor foi de 7,8 cm. O tratamento em 12 pacientes foi a mastectomia, e as demais 40 a excisão ampla. O tipo histológico encontrado em 30 pacientes foi tumores benignos, 11 malignos e 11 de variedade borderline. Após o seguimento médio de 53,93 meses, observaram-se 17 recidivas. Não houve relevância estatística entre a recorrência local e as variáveis avaliadas. Conclusões: A amostra avaliada tem características clínicas e patológicas condizentes com a literatura, com média de idade de 45 anos, tamanho do tumor de 7,8 cm, sendo encontrados na maioria tumor filoides benigno e 33% de recidivas. Não houve significância estatística entre características avaliadas e o risco de recidiva.
Relating emotional intelligence to academic achievement among university students in Barbados.

This study investigated the relationships between e motional intelligence and academic achievement among 151 undergraduate psychology students at The University of the West Indies (UWI), Barbados, making use of Barchard (2001)’s Emotional Intelligence Scale and an Academic Achievement Scale. Findings revealed significant positive correlations between academic achievement and six of the emotional intelligence components, and a negative correlation with negativ e expressivity. The emotional intelligence components also jointly contributed 48 % of the variance in academic achievement. Attending to emotions was the best pre dictor of academic achievement while positive expressivity, negative expressivity and empathic concern were other significant predictors. Emotion-based decision-maki ng, responsive joy and responsive distress did not make any significant relative cont ribution to academic achievement, indicating that academic achievement is only partia lly predicted by emotional intelligence. These results were discussed in the c ontext of the influence of emotional intelligence on university students’ academic achie vement.
Post Treatment of UASB Reactor Effluent in an Integrated Duckweed and Stabilization Pond System for Treating of Domestic Wastewater

Post-treatment of effluent from an Up-flow Anaerobic Blanket (UASB) reactor, which was fed with domestic sewage, has been conducted in an integrated pond system. The UASB reactor was operated at a hydraulic retention time of 8 hrs, the effluent of which was directed to three series of ponds operated in parallel. The system consisted of a series of Duckweed pond (DWP) and stabilization ponds (SP). The main objective of post-treatmen t is removal of bacterial pathogens and further polishing of effluent quality. The results obtained indicated the superiority of the treatment scheme consisted of 2DWP, 2AP, 2DWP) are efficient with regard to organic pollutants removal as 22 reflected residual COD and BOD values (COD: 75mg0 /l, and BOD: 23.7mg0 /l). Also, 83.1 % of TSS were removed. Percentage removal of fecal coliform was around 99.99%. Residual FC counts in the final effluent concentration were extremely variable, ranging from 3E+01 to 7E+03 per 100ml with an average value 8E+02per 100ml. However duckweed ponds with long retention time can be competitive in reducing pathogens. It was demonstrated that duckweed bio-mass production and wastewater treatment for reuse in irrigation can be achieved in one simple system. The highest duckweed production (23g dry weight/m .d) has been recorded in the first (2DWP) and (23.46g dry 2 weight/m .d) of the second (2DWP) . From the available data it can concluded that a treatment system 2 consisting of UASB reactor followed by a series of duckweed and algal ponds is highly recommended for small communities such as rural areas and small cities.
Characterizing the Effects of Multiple Analogs and Extraneous Information for Novice Designers in Design-by-Analogy

This study examines how the quantity of ideas and analog transfer in design-by-analogy (DbA) are affected by multiple analogs and extraneous information, or noise, using a between-subjects, factorial experiment. To evaluate the effects of multiple analogs and noise on ideation, the study uses two metrics in conjunction with one another; namely, number of ideas (most typical in engineering design) and recognition of high-level principle (more common in psychology). The quantity analysis included three components: number of ideas generated, number of ideas that use example products (analogs and noise stimuli), and number of ideas that use analogs. The results indicate two important findings: (1) providing multiple analogs during ideation had a positive impact on ideation quantity and analog transfer. Specifically, the number of analog-based ideas increased with increasing number of analogs but eventually reached a “saturation point”; (2) introducing extraneous information (noise) diminished the successful mapping of analogs to design solutions. The presence of extraneous information did not significantly affect student designers’ ability to identify high-level principles in analogs. The study demonstrated that some extraneous information was perceived as surface similar analogs. Any design analog retrieval method or automated tool will produce extraneous information, and more work is needed to understand and minimize its impact. [DOI: 10.1115/1.4038565]