Miracle-dz/UniFAR-FTUs huggingface dataset:
Nocturnal Panic Attack: Is it an Another Subtype?

Nocturnal panic attack: is it an another subtype? Objective: The aim of this study is to investigate if the nocturnal panic attack has different features and might be considered as a subtype or not. Methods: Sociodemographic data form, SCID-I, SCID-II, Panic and Agoraphobia Scale (PAS), Hamilton Depression Scale (HAM-D), Beck Anxiety Scale, and Bakirkoy Panic Disorder Behavioral Changes Form are applied to the participants. 51 of the 98 patients were suffering from Nocturnal Panic Attacks according to the inclusion/exclusion criteria. Results: It was revealed that 47.9% of the panic disorder patients were suffering from nocturnal panic attacks. The most frequent symptoms in nocturnal panic disorder cases were experiences of feelings like drowning, lethargy, palpitation, vertigo, fear of death, and anxiety. The existence of nocturnal panic attacks is found to be related with severity of the disorder and comorbid depression. Moreover, comorbid sleep disturbances characterized with troubles in falling asleep, difficulty in sustaining sleep, feeling tired in the morning, were observed. There were sleep related avoidances and behavioral changes. Panic disorder patients with nocturnal panic attacks were found to avoid sleeping, or going to bed alone. Conclusions: Panic disorder cases with nocturnal panic attacks had more severe symptoms. From here, it can be concluded that it might be a subtype of panic disorder.
Future Achievements, Passion and Motivation in the Transition from Junior-to-Senior Sport in Spanish Young Elite Soccer Players

Abstract Within the context of the transition from junior-to-senior sport, this study aims in first place to explore differences in young Spanish elite soccer players based on the importance given to getting different achievements in their future (including sport, studies and private life) and, in second place, to explore differences among those players in levels of passion, motivation and basic psychological need. 478 elite youth soccer filled out a questionnaire based on the presented theoretical models. A cluster analysis shows a sport oriented group (N = 98) only interested in becoming a professional, a life spheres balance group (N = 288) characterized by balancing the importance of achievements in the sport sphere, as well as in education and a private life and a group (N = 91) only interested in private life achievements. The life spheres balance group shows higher levels of harmonious passion (η2 = .06, F(2, 475) = 9.990, p < . 001) than the players of the other groups. The life spheres balance group shows higher levels of autonomous motivation (η2 = .10, F(2, 475) = 13.597, p < . 001), autonomy (η2 = .07, F(2, 475) = 6.592, p < . 01) and relatedness satisfaction (η2 = .07, F(2, 475) = 5.603, p < . 01) than the sport oriented group as well as lower levels of amotivation (η2 = .04, F(2, 475) = 6.665, p < . 01) than the private life oriented group. This study suggests players who perceive equal future importance in their life spheres appear to be more resourceful than the other two groups regarding athletes’ internal resources, such as passion and motivation, to cope with the transition to professional soccer.
Multiple choice examinations

from ASA Meeting. 18–22 October 1997, San Diego. Anesthesiology 1997; 86: A482. 5 Baskett PJF, Parr MJA, Nolan JP. The intubating laryngeal mask; results of a multicentre trial with experience of 500 cases. Anaesthesia 1998; 53:
Hippocampal slow EEG frequencies during NREM sleep are involved in spatial memory consolidation in humans

The hypothesis that sleep is instrumental in the process of memory consolidation is currently largely accepted. Hippocampal formation is involved in the acquisition of declarative memories and particularly of spatial memories. Nevertheless, although largely investigated in rodents, the relations between spatial memory and hippocampal EEG activity have been scarcely studied in humans. Aimed to evaluate the effects of spatial learning on human hippocampal sleep EEG activity, we recorded hippocampal Stereo‐EEG (SEEG) in a group of refractory epilepsy patients undergoing presurgical clinical evaluation, after a training on a spatial navigation task. We observed that hippocampal high‐delta (2–4 Hz range) activity increases during the first NREM episode after learning compared to the baseline night. Moreover, the amount of hippocampal NREM high‐delta power was correlated with task performance at retest. The effect involved only the hippocampal EEG frequencies inasmuch no differences were observed at the neocortical electrodes and in the traditional polysomnographic measures. The present findings support the crucial role of hippocampal slow EEG frequencies during sleep in the memory consolidation processes. More generally, together with previous results, they suggest that slow frequency rhythms are a fundamental characteristic of human hippocampal EEG during both sleep and wakefulness, and are related to the consolidation of different types of memories. © 2014 Wiley Periodicals, Inc.
Accurate frameless registration of MR and CT images of the head: applications in planning surgery and radiation therapy.

PURPOSE To evaluate the feasibility and efficacy of a three-dimensional image registration technique for planning skull base surgery, performing frameless image registration for stereotaxic neurosurgery, and staging nasopharyngeal carcinoma. MATERIALS AND METHODS Computed tomographic (CT) and magnetic resonance (MR) images from 35 patients were registered by identifying 12-16 homologous landmarks with each modality. Images were displayed as overlaid sections or rendered three-dimensional scenes. The clarity of the combined images from 15 patients undergoing skull base surgery was compared with that of the conventional displays. RESULTS Images were combined for three applications, with an accuracy of 1-2 mm. For the 15 patients undergoing skull base surgery, the combined images were significantly better at depicting the relationship between bone and lesion than conventional display (P < .01). CONCLUSION MR and CT images of the head can be accurately registered without using external markers or substantially altering image acquisition protocols. The resulting images can show the radiologic information more clearly than conventional viewing.
A Self-Guided Relaxation Module for Telepsychiatric Services: Development, Usefulness, and Feasibility

Objective: A modified form of the standard autogenic relaxation exercise was developed as part of a telepsychiatry project, which aims to deliver mental healthcare to remote areas through the net, and through the agency of non-specialists. This study describes the development and evaluation of a brief and simpler form of a relaxation technique, the Self-Guided Relaxation (SGR). Method: SGR is a systematic technique to focus on muscle groups and feel the heaviness and relaxation through suggestions to induce relaxation in the body. The SGR was taught to 37 patients with different psychiatric disorders over two sessions a week apart. Measures of change used were scores on the Hamilton Anxiety Rating Scale (HAM-A) and a visual analog scale. Its usefulness and feasibility was examined over a follow-up period of one month. Additionally a group of non-specialists was trained in SGR supplemented by audiovisual aids and printed instructions. These therapists rated the ease in learning and administering SGR in patients. Results: There was a consistent reduction in the HAM-A scores over the follow-up period among patients. Improvements were also noted in positive experiences, adherence, depth of relaxation achieved, perceived benefit, and patient satisfaction. Majority of the patients, relatives, and therapists reported that they could administer or practice SGR after having learned the technique in a single session lasting about 30 minutes. The use of audio-video aids and manual was helpful in making the process of learning easy. Conclusions: Preliminary findings of usefulness, feasibility, and acceptance of the SGR were encouraging. These findings pave way for larger, randomized controlled study and for testing applicability of the SGR as a net-based psychological intervention.
The Reamer-Irrigator-Aspirator: Roles and Evidence Supporting its use in Current Orthopaedic Practice

The Reamer-Irrigator-Aspirator (RIA) is an innovative technology created to address physiologic consequences of intramedullary reaming in femur fractures. While multiple physiolgic benefits have been demonstrated in animal studies, currently, no high quality data to demonstrate improved clinical outcomes in trauma patients or support its routine use in the treatment of acute femur fractures. Auto graft obtained from the use of RIA demonstrates osteogenic potential at least equal to iliac crest auto graft with potentially less donor site morbidity. The RIA also demonstrates theoretical benefits in the treatment of conditions which require intramedullary debridement; however, at this time no high level comparative trials exist to support its routine use. Although new complications unique to the RIA device have been reported, most can be avoided with careful preoperative planning and meticulous attention to technique. The RIA has many promising characteristics, but further research is necessary to continue to clarify its clinical role in modern orthopaedics.
Microbiological analysis of bacterial plaque on three different threads in oral surgery.

BACKGROUND Suture is the final act of most oral surgery procedures. The quality of healing after the operation depends on its efficiency. Sutures must not cause inflammation - neither directly nor indirectly. The objective of this study is to compare the bacterial colonization on different suture materials after a third molar extraction. METHODS Thirty patients were randomly selected among people going under third molar extraction; they were divided into 3 groups and one suture type was used on each group. After 7 days distal stitches were removed by a single operator, placed in physiologic solution and analyzed after 2 or 3 hours. Patients followed the same postsurgical protocols; materials used were: Ethicon Silk® 4/0, B. Braun Dafilon® 4/0, and B. Braun Safil® 4/0. RESULTS The amount of cocci and bacilli on the sutures analyzed shows that silk (Ethicon Silk) is the higher level of retention material where monofilament (B. Braun Dafilon) is the lower. There is a difference between monofilament and polyglycolide (B. Braun Safil), as the former is less retentive than the latter, although not significantly so. CONCLUSIONS A less plaque retention, and consequently a fewer bacterial presence, is crucial to minimize the inflammatory process and allow a better tissue healing. Since the capability of brushing and, of course, the final personal hygiene depends on multiple variables, we must use surgical protocols able to minimize the effect of improper cleaning on the healing process: this statement implies the use of low plaque retention materials. The use of monofilament or polyglycolide threads in sutures can help reducing bacterial concentration and therefore promotes a faster and better healing.
Cytology and Colposcopy After Loop Electrosurgical Excision: Implications for Follow‐up

Objective To analyze risk factors associated with residual and recurrent lesions after loop electrosurgical excision procedure and to assess the reliability of cytology and colposcopy in detection of these lesions. Methods Cytology and colposcopy were used to follow up 288 women after treatment by loop electrosurgical excision 3–6 months, 9–15 months, and 24–36 months after the procedure. Results The mean (± standard deviation) postoperative follow-up was 39 ± 13 months (range 24–68 months). Treatment failure, defined as the persistence or recurrence of a cervical lesion, was observed in 20 patients (6.9%). The endocervical localization of the initial lesion (adjusted relative risk [RR] 13.7; 95% confidence interval [CI] 1.3, 150.1; P < .05) and incomplete excision (adjusted RR 9.1; 95% CI 3.0, 27.3; P < .001) were the only independent risk factors for treatment failure. In six cases, a second treatment was performed before the first cytologic and colposcopic visit because of incomplete excisions. The remaining 14 treatment failures were diagnosed by postoperative cytology and colposcopy, ten after the first visit, three after the second, and one after the third. To diagnose the treatment failures, colposcopy and cytology provided complementary information at the first (P < .001) and second postoperative visits (P < .05). Although the sensitivity of cytology was not significantly improved by the association of both methods, the latter decreased the number of residual lesions overlooked by cytology alone and contributed to the diagnosis of 95% of treatment failures in less than 2 years. Conclusion The high detection rate obtained by combining cytology and colposcopy during the first 2 postoperative years may allow more leisurely follow-up schedules after that time and may reduce the consequences of subsequent loss to follow-up.
Ketogenic diet treatment increases longevity in Kcna1‐null mice, a model of sudden unexpected death in epilepsy

Individuals with poorly controlled epilepsy have a higher risk for sudden unexpected death in epilepsy (SUDEP). With approximately one third of people with epilepsy not achieving adequate seizure control with current antiseizure drugs, there is a critical need to identify treatments that reduce risk factors for SUDEP. The Kcna1‐null mutant mouse models risk factors and terminal events associated with SUDEP. In the current study, we demonstrate the progressive nature of epilepsy and sudden death in this model (mean age of mortality (± SEM), postnatal day [P] 42.8 ± 1.3) and tested the hypothesis that long‐term treatment with the ketogenic diet (KD) will prolong the life of Kcna1‐null mice. We found that the KD postpones disease progression by delaying the onset of severe seizures and increases the lifespan of these mutant mice by 47%. Future studies are needed to determine the mechanisms underlying the KD effects on longevity.
Developing measurement systems: an industrial case study

The process of measuring in software engineering has already been standardized in the ISO/IEC 15939 standard, where activities related to identifying, creating, and evaluating of measures are described. In the process of measuring software entities, however, an organization usually needs to create custom measurement systems, which are intended to collect, analyze, and present data for a specific purpose. In this paper, we present a proven industrial process for developing measurement systems including the artifacts and deliverables important for a successful deployment of measurement systems in industry. The process has been elicited during a case study at Ericsson and is used in the organization for over 3 years when the paper was written. The process is supported by a framework that simplifies the implementation of the measurement systems and shortens the time from the initial idea to a working measurement system by the factor of 5 compared with using a standard development process not tailored for measurement systems. Copyright © 2010 John Wiley & Sons, Ltd.
Avaliação da remoção de matéria orgânica de efluente de tanque séptico utilizando filtro anaeróbico preenchido com Luffa cylindrica como meio de suporte

O objetivo deste estudo foi analisar comparativamente a eficiencia de remocao de materia orgânica em tres filtros anaerobios precedidos por tanque septico e preenchidos com diferentes meios suportes para crescimento bacteriano. Os filtros, denominados F1, F2 e F3, foram preenchidos com o fruto seco de bucha vegetal (Luffa cylindrica), aparas de eletroduto corrugado e brita granitica, respectivamente. A remocao de DBO5 nos filtros F1 e F2 variou entre 22 e 57%, enquanto no F3 variou entre 48 e 84%. A remocao de DQO foi entre 33 e 55% no filtro F1, 23 e 45% no F2, e 30 e 52% no F3. Com relacao as eficiencias de remocao de DBO5 e DQO, analise de variância revelou que nao existiram diferencas significativas ao nivel de 5% entre quaisquer pares de filtros estudados, demonstrando que a Luffa cylindrica pode ser utilizada como meio suporte alternativo para crescimento bacteriano em filtros anaerobios, quando a brita ou aparas de eletroduto forem de dificil aquisicao. Nao foi observada degradacao apreciavel na bucha vegetal no periodo de um ano durante o qual o estudo foi desenvolvido.
Blind Spectrum Detector for Cognitive Radio Using Compressed Sensing

Based on the sparse property of the cyclic autocorrelation in the cyclic frequencies domain, this paper proposes a new blind spectrum sensing method which uses the compressed sensing technique in order to detect free bands in the radio spectrum. This new sensing method that presents a relative low complexity has the particularity to perform blind and robust detection with only few samples (short observation time) and without any knowledge about the cyclic frequency of the signal, in contrary to cyclostationary detection methods that are not robust when the sample size is small and might need some information about the signal in order to detect. ROC curves obtained by simulation show the superiority of the new proposed technique over cyclostationary detection under the same conditions, particularly the same observation time.
Interleukin-1,8 and Psychological Factors in Patients with Benign MigratoryGlossitis

Objective: Benign migratory glossitis is a immunologic-psychologic disease with unknown etiology. Aim of this study is evaluation of salivary IL-1 and Il-8 levels in these patients. Study Design: A case-control study was performed on 170 participants (85 with BMG, 85 controls). Unstimulated whole saliva was collected, and interleukin 8 (IL-8) and interleukin 1(IL-1) concentrations were measured. Anxiety level was measured using psychologic and physiologic testing instruments. An independent t test and a Pearson correlation analysis were performed with SPSS. Results: There was a significant difference between the 2 groups regarding the salivary concentrations of IL8 (P ≤ .006) and IL-1 (P ≤ .002). The concentration of salivary cortisol and state and trait anxiety levels in the BMG group were significantly higher than those in the control group (P ≤ .001). Conclusions: Immunologic and psychologic parameters appear associated with BMG and may constitute risk factors of this condition.
CD56, HBME-1 and cytokeratin 19 expressions in papillary thyroid carcinoma and nodular thyroid lesions

Background: Carcinomas of the thyroid follicular epithelium are the most common cancers of the endocrine system. In the diagnosis of thyroid nodules and tumors, the gold standard is histological evaluation. In cases which have morphological overlap, immunohistochemistry is needed for differential diagnosis. The purpose of this study is to investigate the expressions of CD56, HBME-1, cytokeratin 19 (CK19) antibodies in papillary thyroid carcinoma (PTC) and thyroid nodular lesions and their contributions to differential diagnosis. Materials and Methods: In this study, 47 PTCs (26 follicular variant, 21 classic type) and 26 benign thyroid lesions (15 nodular hyperplasia, 10 follicular adenomas, 1 Hurtle cell adenoma) were analyzed retrospectively. HBME-1, CK19, and CD56 antibodies were performed with immunohistochemical methods. The results were evaluated statistically. Results: +3 staining with HBME-1 and CK19 was observed in 72.3% and 83% of patients with PTC. In 95.7% of PTC cases, loss of CD56 expressions in various degrees was identified. A statistically significant difference was detected in HBME-1, CK19, and CD56 expressions between PTCs and benign lesions (P < 0.001). Conclusion: In our study, positive staining of HBME-1, CK19, and loosing expression of CD56 that supports malignancy was found and concluded that CD56 is a helpful antibody for the differential diagnosis of benign and malignant lesions and may increase the diagnostic accuracy when used with HBME-1 and CK19.
Prevalence of Hypertension and Associated Risk Factors Among Diabetic Individuals: The Three-City Study

A cross-sectional study was conducted from 1979 through 1982 in three rural Minnesota cities to describe the natural history of diabetes mellitus. Detailed abstracts of the medical records of physician-defined diabetic individuals were used to construct medical profiles. As part of the effort, the date of physiciandefined hypertension was identified and used to calculate hypertension prevalence. The crude hypertension prevalence was 56.8% for women and 33.99% for men, with an overall crude prevalence of 47.2%. No hypertensive patients were identified among diabetic patients <15 yr old, and most hypertensive diabetic patients were >70 yr old. Hypertension prevalence in diabetic individuals demonstrated a highly significant trend with age (P < .01). Compared with the general population, diabetic individuals had a significantly higher prevalence of hypertension (P < .01), largely explained by the higher prevalence in women. Variables known to be associated with hypertension risk in the general population were also significantly associated with hypertension among diabetic individuals. Older age, being female, nd increased body mass index were strongly associated with hypertension in this study population. Diabetic individuals with hypertension were six times more likely to have renal disease than those without hypertension.
Effects of interleukin (IL)‐13 on immediate‐early response gene expression, phenotype and differentiation of human mast cells. Comparison with IL‐4

The recently cloned interleukin 13 (IL‐13) shares most investigated biological activities on B lymphocytes and monocytes with IL‐4. In this study we investigated the potential role of IL‐13 in regulating human mast cell activities. The effects of IL‐13 on the expression of an immediate‐early response gene (c‐fos), proliferation, expression of mast cell‐associated cell surface antigen (CD54 and Kit), and in vitro differentiation of human mast cells, were investigated. We compared the effect of IL‐13 with that of IL‐4. Both IL‐13 and IL‐4 induced expression of c‐fos in cells from the human mast cell line HMC‐1. This indicates that mast cells express functional receptors for IL‐13. IL‐13 and IL‐4 decreased the proliferation rate of HMC‐1 cells. However, IL‐13 was less potent than IL‐4. Human mast cells constitutively express the adhesion molecule ICAM‐1 (CD54) and the receptor for stem cell factor (Kit) (CD117). The expression of CD54 was increased after treatment with IL‐13 or IL‐4, whereas the expression of Kit was decreased. Also in this action IL‐4 was more potent than IL‐13. By culturing mononuclear cells from cord blood in the presence of stem cell factor there is a differentiation of tryptase‐positive mast cells in the cultures. This process was inhibited when IL‐4 was present. In contrast, IL‐13 did not affect the expression of tryptase during differentiation of stem cell factor dependent cord blood‐derived mast cells. Taken together, these findings indicate that IL‐13 has regulatory effects on human mast cells. The effect overlaps with but is also different from that of IL‐4.