Miracle-dz/UniFAR-FTUs huggingface dataset:
Isolated compression of the pectoral nerve resulting in atrophy of the major pectoral muscle

We report on two cases of isolated damage to a muscle branch of the lateral pectoral nerve. Diagnosis was established by the clinical presentation and electromyographic examination. In the few reported cases of such injuries, the cause was trauma to this region. However, in both of our patients, focal muscle atrophy gradually developed after initiation of training schedules to increase the cross‐section of the major pectoral muscle; we therefore assume that compression injury to the nerve by repetitive muscle contractions may be of pathogenic relevance. Anatomical studies of this region showed that the nerve branches of the lateral pectoral nerve, having to pierce through a connective tissue septum that is thicker here by a few millimeters, may be subjected to additional risk of compression. Early recognition and treatment are vital to prevent associated morbidity of these rare but serious injuries. Muscle Nerve 28: 760–763, 2003
ARE THE POOR THE WEAK LINK? DEMOCRATIC SUPPORT AND INCOME LEVELS IN POST-CRISIS SOUTH KOREA

Abstract Extant literature on democratization documents that ordinary citizens’ unconditional support for democracy is indispensable to democratic consolidation. Yet observers of nascent democracies have repeatedly witnessed that such support often hinges upon their economic conditions. This article argues that income levels have a conditioning effect on this relationship; the Korean poor see democracy as a tool for income redistribution and are less likely than the rich to support it when economic hardships appear to close windows of opportunities for such redistribution. Using survey data from the first round of the Asian Barometer Survey on South Korea, I find strong empirical support for this argument. The implication of this finding for broader literature on democratization is that the weakening of young democracies can be attributed to the poor in times of trouble, or the “weak link. ”
Nasal haemangiopericytoma: report of two cases with literature review

Abstract Haemangiopericytoma (HPC) is a rare vascular tumour produced by proliferation of pericytes. One hundred and thirty-three cases of HPC have been reported in the nose and the paranasal sinuses. We present two more cases. Wide surgical excision via lateral rhinotomy, midfacial degloving, or endonasal removal is the treatment of choice. Radiotherapy has been used post-operatively in cases of incomplete removal. Life-long follow-up is required to evaluate local recurrence and late metastases.
Greater Parametric Downside Risk Aversion

We show that, just as an expected utility maximizer with utility function u responds to a compensated increase in risk by adjusting a control variable to reduce the degree of risk aversion measured by the Arrow–Pratt index Ru=−u′′∕u′ (Diamond & Stiglitz, 1974), so the response to a compensated increase in downside risk entails adjusting the control to reduce the degree of downside risk aversion measured by the Schwarzian Su=u′′′∕u′−(3∕2)Ru2. We also show that, ceteris paribus, increases in Su and in Ru result in reduced exposure to downside risk and, therefore, greater demand for self-protection activities that reduce downside risk to future income. An increase from Su to Sv is characterized by downside risk-averse transformations of utility everywhere along a path from u to v, which together constitute what we define to be a parametric increase in downside risk aversion. These parametric increases yield comparative statics predictions not true if v is simply a downside risk-averse transformation of u, and predictions for incremental changes in risk preferences can be extended immediately to global changes.
The internationalization of the renminbi

1. Internationalization Index of Renminbi 2. Current Situation of Renminbi Internationalization 3. Important Incidents and their Influence 4. Annual Hot Issues on the Internationalization of Renminbi 5. The Historical Opportunity of the Internationalization of Renminbi 6. Challenge of the Internationalization of Renminbi 7. Conclusions and Suggestions
Bilateral laparoscopic ovariectomy in standing mares: 22 cases.

OBJECTIVE To describe a technique for laparoscopic bilateral ovariectomy in standing mares and report the outcome of 22 clinical cases. STUDY DESIGN Prospective study. ANIMALS OR SAMPLE POPULATION A total of 22 mares between 4 and 23 years of age, weighing between 360 and 600 kg. METHODS Mares with normal ovaries, as determined by palpation per rectum, were restrained in standing stocks and sedated with detomidine (0.01 to 0.02 mg/kg intravenously [i.v.]) and butorphanol (0.01 to 0.02 mg/kg i.v.). The laparoscope and instrument insertion sites were infiltrated with 2% lidocaine before incision. One laparoscope portal and two instrument portals were located in each paralumbar fossa. Ovariectomy was accomplished by intracorporeal dissection and ligation of the ovarian pedicles. The two instrument portals in each flank were ultimately connected resulting in a 4 to 5 cm laparotomy to facilitate ovarian removal. RESULTS No major operative or postoperative complications occurred. Minor complications included incomplete hemostasis of an ovarian pedicle with a single ligature (three mares), transient inappetence, pyrexia and incisional infection. Owner satisfaction and cosmetic results were considered excellent. CONCLUSIONS Standing laparoscopic ovariectomy appears to eliminate many of the potential complications associated with traditional surgical methods for ovariectomy and avoids the risk of general anesthesia. CLINICAL RELEVANCE This technique requires minimal laparoscopic instrumentation and will provide surgeons with an alternative approach for bilateral ovariectomy in mares.
Activation processes in a medical linear accelerator and spatial distribution of activation products

Activation products have been identified by in situ gamma spectroscopy at the isocentre of a medical linear accelerator shortly after termination of a high energy photon beam irradiation with 15 × 15 cm field size. Spectra have been recorded either with an open or with a closed collimator. Whilst some activation products disappear from the spectrum with closed collimator or exhibit reduced count rates, others remain with identical intensity. The former isotopes are neutron-deficient and mostly decay by positron emission or electron capture; the latter have neutron excess and decay by β− emission. This new finding is consistent with the assumption that photons in the primary beam produce activation products by (γ, n) reactions in the treatment head and subsequently the neutrons created in these processes undergo (n, γ) reactions creating activation products in a much larger area. These findings are expected to be generally applicable to all medical high energy linear accelerators.
Fusidic Acid Inhibits Hepatic Transporters and Metabolic Enzymes: Potential Cause of Clinical Drug-Drug Interaction Observed with Statin Coadministration

ABSTRACT Fusidic acid (FA), which was approved in the 1960s in many European and Asian countries, has gained renewed interest due to its continued effectiveness against methicillin-resistant Staphylococcus aureus. As rhabdomyolysis has been reported upon coadministration of FA with statins, we aimed to elucidate the underlying molecular mechanisms that contribute to FA-statin drug-drug interactions. Because of the association between rhabdomyolysis and increased exposure to statins, we investigated if cytochrome P450 (CYP) enzymes and transporters involved in the disposition of various statins are inhibited by FA. FA was found to inhibit BCRP and OATP1B1 but not P-gp. In overexpressing cell systems, FA inhibited BCRP-mediated efflux (50% inhibitory concentration [IC50], ∼50 to 110 μM) and OATP1B1-mediated uptake (IC50, ∼4 to 35 μM) of statins at clinically relevant concentrations achievable in the intestine and liver (based on a 550-mg oral dose of FA, the expected maximum theoretical gastrointestinal concentration is ∼4 mM, and the maximum total or unbound concentration in the inlet to the liver was reported to be up to 223 μM or 11 μM, respectively, upon multiple dosing). Similarly, FA inhibited metabolism of statins in human liver microsomes (IC50, ∼17 to 195 μM). These data suggest that FA inhibits at least 3 major dispositional pathways (BCRP, OATP1B1, and CYP3A) and thus affects the clearance of several statins. We confirmed that FA is eliminated via phase 1 metabolism (primarily via CYP3A); however, there is also some phase 2 metabolism (mediated primarily by UGT1A1). Taken together, these data provide evidence for molecular mechanisms that may explain the occurrence of rhabdomyolysis when FA is administered with statins.
Understanding the Role of Places and Activities on Mobile Phone Interaction and Usage Patterns

User interaction patterns with mobile apps and notifications are generally complex due to the many factors involved. However a deep understanding of what influences them can lead to more acceptable applications that are able to deliver information at the right time. In this paper, we present for the first time an in-depth analysis of interaction behavior with notifications in relation to the location and activity of users. We conducted an in-situ study for a period of two weeks to collect more than 36,000 notifications, 17,000 instances of application usage, 77,000 location samples, and 487 days of daily activity entries from 26 students at a UK university. Our results show that users’ attention towards new notifications and willingness to accept them are strongly linked to the location they are in and in minor part to their current activity. We consider both users’ receptivity and attentiveness, and we show that different response behaviors are associated to different locations. These findings are fundamental from a design perspective since they allow us to understand how certain types of places are linked to specific types of interaction behavior. This information can be used as a basis for the development of novel intelligent mobile applications and services.
Broadband High-Gain Beam-Scanning Antenna Array for Millimeter-Wave Applications

A novel method of achieving low profile, broadband microstrip array antennas with high antenna gain is proposed for millimeter-wave applications. The element employs a novel third-order vertically coupled resonant structure that a U-slot resonator in the ground is used to couple with the feeding resonator and the radiating patch, simultaneously. This proposed structure can significantly improve the bandwidth and frequency selectivity without increasing the thickness of the antenna. Then, to achieve the subarray, a new wideband power divider with loaded resonators is employed, which can be used to further improve the bandwidth. To demonstrate the working schemes of broadside radiation and scanned beam, two $4 \times 4$ array antennas are implemented on the same board. Measured results agree well with the simulations, showing a wide bandwidth from 22 to 32 GHz (FBW = 37%) with the gain of around 19 dBi. The beam-scanning array can realize a scanning angle of 25° over a broadband. In addition, due to the filtering features are integrated in the design, the proposed antenna could also reduce the complexity and potential cost of the frontends.
On the IASB’s construction of legitimacy – the case of the agenda consultation project

As an expertise-based private standard-setter, the International Accounting Standards Board (IASB) needs to work continuously to maintain its position as the uncontested rule-making authority of financial reporting in the international regulatory arena. The present paper analyses how the IASB constructs legitimacy in interaction with its constituents. We focus on the specific case of the IASB’s agenda consultation in 2011/2012 as this project was explicitly introduced by the IASB to promote its legitimacy. We carry out a comprehensive study of the agenda consultation that takes into account all board meetings, comment letters and public board activities. We show that the consultation activities in this project were used by the IASB to pronounce its user (investor) orientation, which, however, might be formal rather than substantial, and to integrate a loyal circle of constituents further. It is also shown that the IASB increasingly tried to portray agenda-setting (and standard-setting) as an objective and evidence-based procedure that resonates with constituents’ demands, although it might in fact enlarge the discretionary leeway of IASB (and staff) members.
Team‐Specific Human Capital and Performance

In this paper we explore the effects of team-specific human capital (TSHC) on performance. We do so by delineating between two dimensions of TSHC, relating to team members and the team manager, and then exploring how the two dimensions may interact in shaping performance. Employing a 10-year panel of football teams from the English Premier League we find that team members’ TSHC has a positive and significant effect on team performance, which is positively moderated by managers’ TSHC. Our results attest to the importance of considering both the team member and team manager dimensions of TSHC, and how the performance effects of team members’ TSHC are shaped by managers’ TSHC. Our results stand in stark contrast to the dramatic reduction in managerial tenure that has characterized the English Premier League in recent years.
Role of the intergenic dinucleotide in vesicular stomatitis virus RNA transcription

To investigate the role played by the intergenic dinucleotide sequence of the conserved vesicular stomatitis virus (VSV) gene junction in modulation of polymerase activity, we analyzed the RNA synthesis activities of bicistrionic genomic analogs that contained either the authentic N/P gene junction or gene junctions that had been altered to contain either the 16 possible dinucleotide combinations, single nucleotide intergenic sequences, or no intergenic sequence at all. Quantitative measurements of the amounts of upstream, downstream, and readthrough mRNAs that were transcribed by these mutant templates showed that the behavior of the viral polymerase was profoundly affected by the nucleotide sequence that it encountered as it traversed the gene junction, although the polymerase was able to accommodate a remarkable degree of sequence variation without altogether losing the ability to terminate and reinitiate transcription. Alteration or removal of the intergenic sequence such that the U tract responsible for synthesis of the upstream mRNA poly(A) tail was effectively positioned adjacent to the consensus downstream gene start signal resulted in almost complete abrogation of downstream mRNA synthesis, thus defining the intergenic sequence as an essential sequence element of the gene junction. Many genome analogs with altered intergenic sequences directed abundant synthesis of a readthrough transcript without correspondingly high levels of downstream mRNA, an observation inconsistent with the shunting model of VSV transcription, which suggests that polymerase molecules are prepositioned at gene junctions, awaiting a push from upstream. Instead, the findings of this study support a model of sequential transcription in which initiation of downstream mRNA can occur only following termination of the preceding transcript.
Autism risk following antidepressant medication during pregnancy

Background Previous studies have examined if maternal antidepressant medication during pregnancy increase the risk of autism spectrum disorder (ASD) in the offspring, but the results have been conflicting. Methods In a population-based cohort of 179 007 children born in 2006 and 2007 and followed through 2014 when aged 7 and 8, we estimated relative risks (RRs) of ASD and 95% confidence intervals (CIs) from Cox regression in children exposed to any antidepressant medication during pregnancy, and nine specific antidepressant drugs. Analyses were adjusted for potential confounders and were conducted in the full population sample, and in a clinically relevant sub-sample of mothers with at least one diagnosis of depression or anxiety during life. Results The adjusted RR of ASD in children of mothers who used antidepressant medication during pregnancy was estimated at 1.23 (95% CI 0.96–1.57), and at 1.07 (95% CI 0.80–1.43) in women with a history of depression or anxiety. Analyses of specific antidepressants initially revealed increased RRs of offspring ASD confined to citalopram and escitalopram (RR: 1.47; 95% CI 0.92–2.35) and clomipramine (RR: 2.86; 95% CI 1.04–7.82). Conclusion Medication with antidepressants during pregnancy does not appear to be causally associated with an increased risk of ASD in the offspring. Instead, the results suggest that the association is explained by factors related to the underlying susceptibility to psychiatric disorders. Based on these findings, the risk of ASD in the offspring should not be a consideration to withhold treatment with commonly used antidepressant drugs from pregnant women.
Acute blood pressure changes are related to chronic effects of resistance exercise in medicated hypertensives elderly women

A previous study observed that the chronic effects of aerobic training on blood pressure (BP) are related to acute BP responses after a single bout of aerobic exercise. However, whether similar responses are observed with resistance exercise (RE) remains obscure. Thus, this study analysed the relationship between the acute BP responses to a single bout of RE and chronic changes in resting BP after a RE training in medicated hypertensive elderly women.
Social structures depend on innate determinants and chemosensory processing in Drosophila

Flies display transient social interactions in groups. However, whether fly–fly interactions are stochastic or structured remains unknown. We hypothesized that groups of flies exhibit patterns of social dynamics that would manifest as nonrandom social interaction networks. To test this, we applied a machine vision system to track the position and orientation of flies in an arena and designed a classifier to detect interactions between pairs of flies. We show that the vinegar fly, Drosophila melanogaster, forms nonrandom social interaction networks, distinct from virtual network controls (constructed from the intersections of individual locomotor trajectories). In addition, the formation of interaction networks depends on chemosensory cues. Gustatory mutants form networks that cannot be distinguished from their virtual network controls. Olfactory mutants form networks that are greatly disrupted compared with control flies. Different wild-type strains form social interaction networks with quantitatively different properties, suggesting that the genes that influence this network phenotype vary across and within wild-type populations. We have established a paradigm for studying social behaviors at a group level in Drosophila and expect that a genetic dissection of this phenomenon will identify conserved molecular mechanisms of social organization in other species.
Organized for Parliament? Explaining the Electoral Success of Radical Right Parties in Post-Communist Europe

Over the last three decades a great deal of research has been carried out in an attempt to explain the electoral performance of radical right parties in Europe. Most approaches concentrate on demand-side determinants and have some limitations. We compensate for these shortcomings and focus on the context of party competition and supply-side determinants (consistency of ideological discourse, functioning party propaganda, the continuity of the leader in office and strong party organization) to explain the electoral success of radical right parties in post-communist Europe. We conducted our analysis at party level in nine radical right parties in four countries from Central and Eastern Europe (Bulgaria, the Czech Republic, Hungary and Romania) between 1990 and 2014. The bivariate and multivariate (ordinal logistic regression) analyses draw on unique data collected from primary and secondary sources.
Intonation features of the expression of emotions in Spanish: preliminary study for a prosody assessment procedure

This study aimed to find out what intonation features reliably represent the emotions of “liking” as opposed to “disliking” in the Spanish language, with a view to designing a prosody assessment procedure for use with children with speech and language disorders. 18 intonationally different prosodic realisations (tokens) of one word (limón) were recorded by one native Spanish speaker. The tokens were deemed representative of two categories of emotion: liking or disliking of the taste “lemon”. 30 native Spanish speakers assigned them to the two categories and rated their expressiveness on a six‐point scale. For all tokens except two, agreement between judges as to category was highly significant, some tokens attracting 100% agreement. The intonation contours most related to expressiveness levels were: for “liking”, an inverted U form contour with exaggerated pitch peak within the tonic syllable; and for “disliking”, a flat melodic contour with a slight fall.
ORBITOCRANIAL WOODEN FOREIGN BODY: A PRE‐, INTRA‐, AND POSTOPERATIVE CHRONICLE CASE REPORT

OBJECTIVEIntraorbital wooden foreign bodies—usually from a low-velocity puncture—are elusive and demand a low threshold for further imaging. In patients with traumatic injuries, orbital and intracranial air from fractures may be present, and it is particularly easy to overlook a wooden fragment CLINICAL PRESENTATIONA 53-year-old equestrian was kicked in the face by the rear hoof of a horse. The event was captured on video by her husband. Although no obvious entry point in and around the eye was observed, her ocular examination was notable for superior orbital fissure syndrome and increasing intraocular pressure in the left eye. Closer inspection revealed a 5-mm laceration above her superior lid margin; imaging revealed a foreign body at the orbital apex with apparent communication with the cranial vault. INTERVENTIONWe proceeded with cranio-orbital exploration because of the risk of continued ocular damage in the setting of increasing intraocular pressure and the potential for infection of both the eye and the intracranial space from a suspected foreign body. A 3.0 cm × 0.5 cm fragment was found lodged in the orbital apex and removed. CONCLUSIONThe patient recovered well after surgery and a course of antibiotics and has returned to riding. This case report presents an algorithm for approaching cranio-orbital foreign objects of unclear identity and the favorable outcomes that may be achieved.
CYP1A1 and GSTM1 genetic polymorphisms in lung cancer populations exposed to arsenic in drinking water

Region II of Chile is the most important copper mining area in the world and it shows the highest lung cancer mortality rate in the country (35/100 000). The population in Antofagasta, the main city of Region II, was exposed from 1958 to 1970 to 860 µg m−3 arsenic (As) in drinking water and has currently been declining to 40 µg m−3. Glutathione serves as a reducing agent and glutathione S-transferase (GST) may have an important role in As methylation capacity and body retention. In the current study, the null genotype of GSTM1 and the MspI polymorphism of CYP450 1A1 were investigated in lung cancer patients and in healthy volunteers of Region II. In males, the 2A genotype of MspI represented a highly significant estimated relative lung cancer risk (OR = 2.60). Relative lung cancer risk for the combined 2A/null GSTM1 genotypes was 2.51, which increased with the smoking habit (OR = 2.98). In Region II, the cancer mortality rate for As-associated cancers at least partly might be related to differences in As biotransformation. Genetic biomarkers such as 2A and GSTM1 polymorphisms in addition to DR70 as screening biomarkers might provide relevant information to identify individuals with a high risk for lung cancer as prevention and protection actions to protect public health.