Miracle-dz/UniFAR-FTUs huggingface dataset:
Pharmaceutical dosage forms : tablets

"Principles of Improved Tablet Production System Design, Garnet E. Peck, Neil R. Anderson, and Gilbert S. Banker Coating of Pharmaceutical Solid-Dosage Forms, Stuart C. Porter and Charles H. Bruno Particle-Coating Methods, Dale E. Wurster Sustained Drug Release from Tablets and Particles Through Coating, Rong-Kun Chang and Joseph R. Robinson The Pharmaceutical Pilot Plant, Charles I. Jarowski Tablet Production, Robert J. Connolly, Frank A. Berstler, and David Coffin-Beach The Essentials of Process Validation, Robert A. Nash Stability Kinetics, Samir A. Hanna Quality Assurance, Samir A. Hanna "
Personality Profiles of Patients with Psychogenic Nonepileptic Seizures

Despite the substantial prevalence of psychogenic disorders (from 50% to 70% of patients who report to physicians of various specialities are treated for psychogenic, functional disorders), these disorders continue to be relatively poorly understood (Hamilton et al., 1996; Mace & Trimble, 1996). Psychogenic nonepileptic seizures (PNES) are one variety of psychogenic disorders. PNES are sudden changes in behaviour, usually of limited duration, which imitate an epileptic attack, but are not accompanied by EEG changes occurring during a genuine epileptic attack.
Nominalization and ellipsis in the Greek DP

Two DP-internal phenomena in Greek are being distinguished: nominal subdeletion and substantivization. We show that the two cannot be analyzed as instances of the same phenomenon, and that a unified account in terms of ellipsis is untenable. Instead, nominal subdeletion is analyzed as a genuine case of nominal ellipsis, and substantivization as nominalization in the sense of Chierchia (1998). Two novel results can be drawn as consequences of our analysis. First, the question of whether the omitted constituent in subdeletion is ofzero (lexical) or phrasal category can be dispensed with, as it is simultaneously both (just a lexical N(oun) or N with a merged A(djective)). Second, the 'expletive' definite determiner which appears in generic DPs is not at all expletive but contentful: it is the locus of the nominalization operator.
Cancer Gene Therapy: Targeted Genomedicines

Given the fact that malignant cells proliferate more rapidly than normal cells, damage to the cancer cells is anticipated to be markedly greater than normal cells. However, cancer cells generate chemoresistance mechanisms within the tumor microenvironment, while undesired toxicity may occur in the normal cells. For example, in colorectal cancer (CRC), there exist well-described sequences of mutational events that evince the shift of normal colon epithelium to premalignant adenoma and malignant adenocarcinoma. These events are 1) loss of the function of the adenomatous polyposis coli (APC) gene (encoding a protein involved in cell adhesion and transcription) in up to 85% of all cases of CRC, 2) mutation of KRAS (a GTP-ase that controls cell proliferation) in 50–60% of all cases of CRC, and 3) downregulated expression of the cell-adhesion transmembrane glycoprotein E-cadherin in almost 50–60% of all cases of CRC. Mutations in the mismatch-repair genes MLH1 and MSH2 contribute to genetic instability. Besides, there exist a number of genes alterations leading cells toward remodeling that include: 1) SMAD4 involved in the transforming growth factor signal transduction suppressing epithelial-cell growth, 2) INK4A involved in the retinoblas‐ toma tumor-suppressor pathway, and 3) TP53 alterations increasing the resistance of cancer cells to apoptosis [1]. Similar molecular/cellular alterations occur in various solid tumors, highlighting the intricacy of biological events leading to initiation and progression of malignancies. Therefore, necessity for development and advancement of more effective modalities targeting such genetic changes is perceptible to achieve successful cancer treatment and cure. After decades of disappointment, targeted therapy of cancer has been advanced by integration of immunotherapy as well as gene and cell therapy. As proof-ofconcept, recent clinical trials (e.g., anti-CTLA4 antibody, ipilimumab) have shown signifi‐
A Comparative Study of Tear Film Stability & Secretion in Pterygium Patients - Diabetic vs. Non-diabetic. -

Aims, settings & design: The present prospective study was conducted on 62 ophthalmology patients over a period of 1 year, between May 2012 to April 2013 in rural set up to compare Schirmer's test’s and the tear film breakup time test’s diagnostic utility to detect tear film abnormalities in pterygium patients having diabetes vs control group Materials & Methods: Our study involved 62 pterygium patients equally categorized into two groups. Group A comprised of diabetic patients & Group B of non-diabetic patients. The tear film stability & secretion were estimated in patients of both the groups. Results: The mean Schirmer's test 1, mean Schirmer's test 2 & mean tear film breakup time values were 13.64 mm, 11.23 mm & 12.76 sec in Group A & 17.63 mm, 14.51 mm & 17.73 sec in Group B respectively. There was a statistically significant difference in the dry eye results between both the groups (p value
TOWARDS CRISES PREVENTION: FACTORS AFFECTING LENDING BEHAVIOUR

The purpose of this study is to examine the behavior of bank lending in ASEAN economies. For this purpose, macroeconomic and bank related factors are identified from existing literature, defining the lending behavior. Data is collected from official sources like web pages, company’s annual report and online databases. A sample of five banking firm from four ASEAN economies is collected over 2011-2017 with annual observations. Regression analysis indicates the fact that both macroeconomic factors (GDP growth, inflation) are playing their significant role in defining the lending behavior of bank as measured through net loans and unused commitments. From bank related variables, liquidity ratio, risk, return on assets and equity are found to be significant determinant for bank lending. it is highly suggested that credit managers in banking firms, and related departments should use these findings as documentary evidence for the future decision making. Additionally, these findings are also useful facts for country administration, dealing with the macroeconomic factors and their direct influence on bank lending. However, various limitations are also observed which can be addressed in upcoming research studies. Sample size is limited to five banking firms from each state with seven years of time period. At second, specific macroeconomic and bank related measures are used which can be expanded in coming studies.
Documenting Undocumented Motives Influencing the Career Choice of the First-Year Science and Math Student Teachers in Indonesia

The aim of this study was to investigate the motives that were instrumental in driving the firstyear science and math student teachers to be a teacher at one public university in Sumatra, Indonesia. A questionnaire and semi-structured interviews were used to collect the data. 378 participants completed questionnaires consisting of 318 females and 60 males while the interview data were collected from voluntary participants. The data of the fulfilled questionnaires were calculated as percentage of their whole results while the data of the interviews were carefully analysed by looking at the responses from all interviewees. Our results indicated that there was a trend among participants to regard highly on first altruistic, second intrinsic, and third extrinsic motives to be a teacher as a career by going into teacher education programs. Policy implications are also discussed.
A study on the green hotels in Egypt.

The study aims at developing green hotels in Egypt to overcome environmental, economic and social problems of conventional hotels. Studied also were the drivers, obstacles, benefits of green hotels, the factors that have helped their owners in the process of going to green, the most important green programs applied, as well as the most important procedures necessary for hotels to go green and how to market them. The practical study was conducted through personal interviews with officials of environmental management in five-star hotels in Sharm El Sheikh. The study recommended hotels to assign a special department for environmental affairs, and to act in accordance to environmental written policies, and to start with the goals that are easily applicable and of quick return. Governmental financial, technical and legislative supports are needed
SOME OF MY BEST FRIENDS ARE OLD: A QUALITATIVE EXPLORATION OF MEDICAL STUDENTS' INTEREST IN GERIATRICS

This paper provides insight into the reasons underlying medical students' interest in geriatrics. Semi-structured interviews, informed by attitude theory, were conducted with first-year medical students who indicated that they were not interested in geriatric medicine (n = 10) and those who indicated that they were moderately to very interested in geriatrics (n = 10). The interviews were analyzed qualitatively. While most students in both groups did not plan on pursuing geriatric medicine, differences were found between the two groups. Students who expressed an interest in geriatrics had more positive and negative experiences with older adults, were more comfortable with palliative care, did not view their patients as responsible for their illnesses, and held more fears about aging and death than did those students who were not interested in geriatrics. The discussion of the results focuses on the role of experience in students' interest in geriatrics, and their beliefs about personal gain and loss and the field of medicine in general. Implications for educators, including the need to increase exposure to older patients and geriatric medicine for all students, are discussed.
Integrated Theory and Knowledge Development in Nursing

Chapter 1 Nursing's Fundamental Patterns of Knowing Knowledge for a Practice Discipline Knowing and Knowledge Overview of Nursing's Patterns of Knowing Processes for Developing Nursing Knowledge Why Develop Nursing's Patterns of Knowing? Reflection and Discussion Chapter 2 The History of Knowledge Development in Nursing From Antiquity to Nightingale From Nightingale to Science Knowing Patterns in the Early Literature The Emergence of Nursing as a Science Trends in Knowledge Development The Contexts of Knowledge Development Reflection and Discussion Chapter 3 Emancipatory Knowledge Development The Concept of Emancipatory Knowing The Rebirth of Emancipatory Knowing in Nursing The Dimensions of Emancipatory Knowing Reflection and Discussion Chapter 4 Ethical Knowledge Development Ethics, Morality, and Nursing Overview of Ethical Perspectives Nursing's Focus on Ethics and Morality Dimensions of Ethical Knowledge Development Reflection and Discussion Chapter 5 Personal Knowledge Development Personal Knowing in Nursing Conceptual Meanings of Personal Knowing Dimensions of Personal Knowing Reflection and Discussion Chapter 6 Aesthetic Knowledge Development Art and Aesthetics Aesthetic Knowing The Dimensions of Aesthetic Knowing Reflection and Discussion Chapter 7 Empiric Knowledge Development: Conceptualizing and Structuring What Is Empiric Theory? Creating Conceptual Meaning What Is a Concept? Methods for Creating Conceptual Meaning Structuring and Contextualizing Theory Reflection and Discussion Chapter 8 Description and Critical Reflection of Empiric Theory What is this? The Description of Theory How Does It Work? The Critical Reflection of Theory Reflection and Discussion Chapter 9 Confirmation and Validation of Empiric Knowledge Using Research Theory-Linked Research and Isolated Research Challenges Related to Theory-Linked Research Refining Concepts and Theoretic Relationships Designing Theoretically Sound Empiric Research Developing Sound Theoretic Research Reflection and Discussion Chapter 10 Confirmation and Validation of Empiric Knowledge in Practice Theory- and Evidence-Based Practice Refining Conceptual Meaning Validating Theoretic Relationships and Outcomes in Practice Methodologic Approaches to Validation of Relationships and Outcomes Expected Outcomes That Flow From Theoretic Reasoning Implementing a Formal Method of Study Reflection and Discussion
The Primacy of Family in Elder Care Discourse

Abstract Although public and institutional policy states that the presence of family to provide care should not limit older people's access to public services, it does occur in practice. When family members are perceived as being able to contribute to the care of their elderly relatives, the frequency and duration of public sector support diminishes. This reality is particularly important to address with respect to ethnic elders where the perception and expectation of increased family involvement by public sector workers is commonplace. This article reports on the findings of a qualitative study addressing the experience of access among ethnic minority elderly women. It highlights the primary role of families in the discourse of home care and the resulting pressures this places on older ethnic women and their families. Suggestions for improving services are also mentioned.
Toxoplasmosis in HIV/AIDS Patients - A Living Legacy

The coccidian Toxoplasma gondii (T. gondii) is a ubiquitous, intracellular, protozoan parasite that causes toxoplasmosis, a cosmopolitan zoonotic disease. Toxoplasma infections are reported in approximately half of the world’s population but most are asymptomatic. T. gondii may serve as one factor that can enhance the immunodeficiency found after HIV-1 infections. Co-infection with other pathogens in humans infected with HIV-1 may enhance the progression of the disease to AIDS (Lin & Bowman, 1992). In concurrence with HIV infection, cerebral toxoplasmosis (CT) occurs primarily due to reactivation of latent Toxoplasma infection and is one of the most frequent opportunistic infections, particularly in patients with full-blown AIDS. CT is the most common clinical presentation of toxoplasmosis (Luft & Remington, 1992), and is one of the most frequent causes of focal intracerebral lesions that complicates AIDS (Nissapatorn et al, 2004). CT is undoubtedly a serious life-threatening disease but it is treatable when there is a timely diagnosis and prompt treatment, and there are no other concurrent co-infections. When HIV-infected patients develop CT this poses many diagnostic and therapeutic challenges for clinicians (Israelski & Remington, 1992), particularly in developing countries where the infrastructure is limited but the number of patients infected with HIV is increasing. This chapter focuses on the clinico-epidemiological aspects of toxoplasmosis in HIV/AIDS patients at the time of transition to treatment with highly active anti-retroviral therapy (HAART). The course of toxoplasmosis in HIV/AIDS patients should be able to provide us with a better understanding of the clinical scenario and future management of this so-called “enigmatic parasite” of the tropics.
The psychological aspects of physical illness and disability

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Immunotherapy as an effective tool in allergy treatment

Allergen-specific immunotherapy and allergen reduction are the only interventions in allergic diseases with the potential to reduce symptoms in the long term. The clinical value of specific immunotherapy in the treatment of allergic diseases has been questioned for the last 20 years in spite of substantial documentation of efficacy. In the evaluation of the relative advantages of immunotherapy compared to exclusively pharmacologic treatment of allergic diseases, several aspects such as the magnitude of efficacy (short term and long term), practical applicability, sideeffects, and costs and durations are important factors. The present review will focus on the magnitude of efficacy and side-effects. In Hymenoptera venom allergies, immunotherapy represents the only curative treatment, and the only real option for protection of patients against life-threatening, sting-induced anaphylaxis (1). Drug treatment in allergic rhinitis and asthma is widely used and is clinically effective. However, pharmacotherapy has limitations, as its long-term efficacy in relation to preventing the development of chronic, irreversible destruction of mucous membranes is almost unknown.
The Availability of Traditional and Family-Friendly Employee Benefits among a Cohort of Young Women, 1968–1995

Based on a nationally representative sample of young women who ever worked between 1968 and 1995 (N = 2,594), findings of a study on the availability of traditional and family-friendly employee benefits are presented. The highest concentrations (70% to 95%) of women held jobs with traditional benefits such as medical coverage, life insurance, and retirement pensions, while the proportions holding jobs with family-friendly benefits such as paid and unpaid maternity leave and flexible work hours were about half that or less. In any given survey year, between 9% and 11% of working women held jobs without benefits, while, over their work histories, 39% had held at least one job without benefits. The effects of 10 correlates on the number of years working women held jobs with specific employee benefits were also assessed. Correlates included age; highest grade completed; number of employers; number of children ever had; race; and years of full-time employment, marriage, public assistance, private-sector employment, and union membership. A positive relationship was found between full-time employment and nearly all employee benefits, while number of children had no effect on all but one benefit, flexible menu of benefits. Most significant, race was found to affect whether working women ever held jobs with certain employee benefits, as well as the number of years they were likely to hold such jobs. Despite longer full-time work histories, Black women were less likely than White women to have jobs with job-related training programs and with several family-friendly benefits. Implications for retaining principles of affirmative action, workplace strategies, and other policies are discussed.
Black Tea and Green Tea in Reducing Children Dental Caries

Dental caries is a most prevalent oral disease in children. There were tendency of diverse children drink consumption including soft drinks that attracts by its taste and flavor and causing dental caries. Earlier study suggested that tea had important element in dental caries inhibition. Hence this study was conducted to evaluate and compare pH of saliva after rinsing with green tea and black tea. Methods for his study was conducted among thirty two healthy school children between 10-12 years old. The subjects who fulfilled inclusion and exclusion criteria were selected and randomly divided into two groups. The first group had rinsing with green tea and the other group with black tea. They were asked to rinse for one minute after sugary soft drink consumption. Then salivary pH were measured using pH meter. Statistical analysis was done using Mann Whitney test. p < 0.05 was considered statistically significant. Results of this study showed that there was no statistically significant difference among subjects rinsing for one minute with green tea and black tea after sugary soft drink consumption. But green tea showed much better effect in rising salivary pH. As the conclusion that green tea showed a promising greater rising on salivary pH than black tea after sugary soft drink consumption in children. Keyword(s) : dental caries, tea, children
Economic Impact of Retirement Migration on the Texas Hill Country

Early in the 20th century economies stagnated and populations dwindled in the Texas Hill Country. Over the past three decades, however, several Hill Country counties have experienced a remarkable reversal of demographic fortune, culminating in a notable influx of older migrants with wealth. This study documents this flow with census data for 34 counties in Texas Hill Country between 1965 and 1990. Correlation statistics show a close relationship between elderly inmigrant flows and economic resurgence in several counties. In particular, elderly in-migration rates were closely tied to increases in county income, as well as growth in the service, retail, and construction sectors.
Neoadjuvant Chemotherapy in Gynecologic Cancers

Neoadjuvant chemotherapy is introduced in many gynecologic cancers such as cervical and ovarian cancer. The aim of using neoadjuvant chemotherapy is to reduce the tumor size prior to the principle treatment, either radiation or surgery. The benefit of reducing tumor size can increase the operability and decrease the morbidity in many types of gynecologic cancers. Besides this, neoadjuvant chemotherapy might control the micrometastatic disease to decrease the distant metastasis (Benedetti-Panici et al., 1998; Buda et al., 2005; Chua, 2010). On the other hand, in patients who did not respond to chemotherapy, however, the administration of neoadjuvant chemotherapy risks delaying the principle treatment. In this chapter, literature pertaining to neoadjuvant chemotherapy for gynecologic cancer will be presented in five parts, categorized by types of cancers; cervical cancer, ovarian cancer, endometrial cancer, vulvar cancer, and vaginal cancer.
Results from an exploratory study of sun protection practice: Implications for the design of health promotion messages

Purpose – The primary aim of the research reported here is to provide strategic guidance for the development of a national communication strategy to improve sun protection practice amongst young people.Design/methodology/approach – The research adopted an exploratory approach, employing qualitative focus groups to represent three population groups, mothers, teenagers and young adults living independently of the family home. A total of 12 focus groups were conducted (with six to eight participants per group) in the UK. Participants were recruited door‐to‐door using quota sampling methods.Findings – Consistent with other studies, awareness of sun protection measures was high compared with actual practice. A number of factors were identified which help to explain this behaviour deficit. These include environment and exposure context, financial cost, understanding of protection process, behavioural influence and control, experiential learning and benefits attached to tanning.Originality/value – While the find.