Miracle-dz/UniFAR-FTUs huggingface dataset:
Testing Is More Desirable When It Is Adaptive and Still Desirable When Compared to Note-Taking

Testing is a well-established desirable difficulty. Yet there are still some open issues regarding the benefits of testing that need to be addressed. First, the possibility to increase its benefits by adapting the sequence of test questions to the learners’ level of knowledge has scarcely been explored. In view of theories that emphasize the benefits of adapting learning tasks to learner knowledge, it is reasonable to assume that the common practice of providing all learners with the same test questions is not optimal. Second, it is an open question as to whether the testing effect prevails if stronger control conditions than the typical restudy condition are used. We addressed these issues in an experiment with N = 200 university students who were randomly assigned to (a) adaptive testing, (b) non-adaptive testing, or note-taking (c) without or (d) with focus guidance. In an initial study phase, all participants watched an e-lecture. Afterward, they processed its content according to their assigned conditions. One week later, all learners took a posttest. As main results, we found that adaptive testing yielded higher learning outcomes than non-adaptive testing. These benefits were mediated by the adaptive learners’ higher testing performance and lower perceived cognitive demand during testing. Furthermore, we found that both testing groups outperformed the note-taking groups. Jointly, our results show that the benefits of testing can be enhanced by adapting the sequence of test questions to learners’ knowledge and that testing can be more effective than note-taking.
Envelope Detection for an ADC-Relaxed Double-Sideband Low-IF CW Doppler Radar

In this paper, we propose a new envelope detection (ED) method to reduce the analog-to-digital converters’ (ADCs) sampling rate from 20 kHz to 20 Hz in a double-sideband low-intermediate-frequency (IF) continuous-wave Doppler radar. Compared with the conventional synchronous demodulation (SD) method, which typically consumes a large amount of ADC resources, the proposed ED can achieve the same results on both mechanical vibration and human vital sign detection. Meanwhile, this paper also describes in detail the hardware implementation of carrier compensation and envelope detectors to recover and extract the envelopes in the IF domain. Experiments also show that, when the IF carrier frequency is higher than 1 kHz, the signal-to-noise ratio performance of ED would be comparable to that of SD.
Prosodic aspects of repetition in Swedish-speaking children with developmental language disorder

Abstract Purpose: To examine repetition of stress and tonal word accents in real words and non-words in Swedish-speaking children with developmental language disorder (DLD), and to investigate the relation of prosodic repetition to measures of language ability. Method: A cross-sectional study was undertaken with 30 monolingual Swedish-speaking children with DLD, mean age 4;11 (years;months) and 29 age-matched controls, mean age 5;1, who repeated words and non-words with systematically varying prosody. Group differences for the repetition of prosodic features, and correlations between repetition and phonology, grammar, and vocabulary, were explored. Result: Children with DLD performed below controls on repetition of prosodic features of words and non-words. Repetition of stress and tonal word accent was not correlated with phonological production or receptive vocabulary, but a significant correlation was found between stress repetition in words and expressive grammar. Conclusion: Repetition of stress and tonal word accents is challenging for children with DLD acquiring Swedish as their first language, but may not be a good indicator of general language ability. Prosody should be taken into account when interpreting results from clinically used word repetition (WR) and non-word repetition (NWR) tasks.
Fall Prevalence and Contributors to the Likelihood of Falling in Persons With Upper Limb Loss

BACKGROUND Arms are important for locomotor stability and preventing falls by controlling whole-body angular momentum, redirecting the body's center of mass, and providing support to arrest descent. Hence, upper limb loss (ULL) can increase fall risk. However, the prevalence of falls and factors that influence fall risk have not previously been reported for people with ULL. OBJECTIVE This study quantified fall prevalence in persons with ULL at or proximal to the wrist and identified clinical factors that contributed to the likelihood of falling. DESIGN This was a cross-sectional study. METHODS Factors including body and health characteristics, activity level, fall history, prosthesis use, and balance confidence were determined for persons with ULL proximal to the wrist using an online survey. Logistic regression analyses assessed the contribution of these factors to the classification of fallers (≥2 falls in previous year) and nonfallers. RESULTS A percentage (28.6%) of participants (n = 105) reported experiencing 2 or more falls in the past year. The regression model (R2 = 0.473) correctly classified 84.5% of cases and indicated that increased likelihood of falling was significantly influenced by reduced balance confidence, use of upper limb prostheses, and reduced physical capabilities. LIMITATIONS Data were collected online from a convenience sample, and fall classification was based on retrospective data. CONCLUSIONS Falls in persons with ULL are prevalent, suggesting that clinicians should use screening methods to identify at-risk individuals. Balance confidence, use of upper limb prostheses, and perceived physical capabilities could be useful screening metrics. Research is warranted to better understand the factors that underlie fall risk in persons with ULL and the efficacy of therapeutic interventions capable of mitigating fall risk.
Case report of traumatic abdominal wall hernia caused by seat belt

Rationale: Traumatic abdominal wall hernia (TAWH) is a rare form of hernia that is caused by disruption of the abdominal wall musculature and fascia. The diagnostic criteria and classification of TAWH are still unclear; furthermore, the ideal timing and method of surgical treatment are still unclear. Herein, we report a case of TAWH and describe the surgical approach used. Patient concerns: A 71-year-old Han Chinese female presented for swelling in the right lower abdominal quadrant. The patient underwent exploratory laparotomy because of a car collision before 1 year ago. Diagnosis: She was finally diagnosed with TAWH according to the abdominal computed tomography (CT) and surgery. Interventions: She was performed with an open surgery to repair the TAWH. Outcomes: The patient was discharged without complications and showed no recurrence or complications during a follow-up period of 6 months. Lessons: TAWH is a rare form of hernia that presents a diagnostic and therapeutic challenge. The appropriate timing and approach of surgical treatment for TAWH depend on a case-by-case basis. This case highlights that delayed selective surgery may be more suitable for stable patients.
Advanced gastric cancer: the value of systemic and intraperitoneal chemotherapy

Several possibilities in treating advanced gastric cancer exist. Radical surgery associated with chemotherapy represents the cornerstone. Which one is more effective among neoadjuvant, adjuvant or perioperative chemotherapy is still a matter of debate. Several innovative results showed the necessity to keep increasingly into consideration the intraperitoneal administration of chemotherapies. Moreover, classical drugs and their ways of administration should be combined with the new ones to improve results. Lastly the prevention of recurrence should be considered: one possibility is to administer intraperitoneal chemotherapy earlier in the therapeutic algorithm. (www.actabiomedica.it)
Improving the Performance and Endurance of Encrypted Non-Volatile Main Memory through Deduplicating Writes

Non-volatile memory (NVM) technologies are considered as promising candidates of the next-generation main memory. However, the non-volatility of NVMs leads to new security vulnerabilities. For example, it is not difficult to access sensitive data stored on stolen NVMs. Memory encryption can be employed to mitigate the security vulnerabilities, but it increases the number of bits written to NVMs due to the diffusion property and thereby aggravates the NVM wear-out induced by writes. To address these security and endurance challenges, this paper proposes DeWrite, a secure and deduplication-aware scheme to enhance the performance and endurance of encrypted NVMs based on a new in-line deduplication technique and the synergistic integrations of deduplication and memory encryption. Specifically, it performs low-latency in-line deduplication to exploit the abundant cache-line-level duplications leveraging the intrinsic read/write asymmetry of NVMs and light-weight hashing. It also opportunistically parallelizes the operations of deduplication and encryption and allows them to co-locate the metadata for high time and space efficiency. DeWrite was implemented on the gem5 with NVMain and evaluated using 20 applications from SPEC CPU2006 and PARSEC. Extensive experimental results demonstrate that DeWrite reduces on average 54% writes to encrypted NVMs, and speeds up memory writes and reads of encrypted NVMs by 4.2 × and 3.1 ×, respectively. Meanwhile, DeWrite improves the system IPC by 82% and reduces 40% of energy consumption on average.
Radiomics for Identification of Active Bone Marrow from CT: An Exploratory Study

The radiation dose received by the pelvic Bone Marrow (BM) is a predictive factor for Hematologic Toxicity (HT) occurrence in the treatment of anal cancer. For this reason it is important to avoid BM during radiotherapy. In particular, the standard strategy in these cases consists in the identification of hematopoietically active BM (actBM), i.e. the part of BM in charge of blood cells generation, on 18FDG-PET, FLT-PET or MRI, but no approached have been developed for identifying actBM from CT images. This exploratory study aims to use radiomics for detecting actBM on CT sequences. Our approach is based on the extraction of 36 first-order and texture (second-order) features for each CT slice. These features are used as input of a Decision Tree (DT) classifier able to discriminate between active and inactive BM regions on the images. This method was applied to five patients affected by carcinoma of the anal canal and the obtained actBM segmentation was compared with the standard actBM identification from 18FDG-PET (reference standard, RS). Our results show that actBM identification in lumbosacral and iliac structures using radiomics overlaps the RS for more than 75% in 4 out of 5 patients.
The Singularity of Literature

Winner of the ESSE (European Society for the Study of English) Book Award for Literature 2006 Literature and the literary have proved singularly resistant to definition. Derek Attridge argues that such resistance represents not a dead end, but a crucial starting point from which to explore anew the power and practices of Western art. In this lively, original volume, the author: * considers the implications of regarding the literary work as an innovative cultural event, both in its time and for later generations; * provides a rich new vocabulary for discussions of literature, rethinking such terms as invention, singularity, otherness, alterity, performance and form; * returns literature to the realm of ethics, and argues the ethical importance of the literary institution to a culture; * demonstrates how a new understanding of the literary might be put to work in a 'responsible,' creative mode of reading. *The Singularity of Literature is not only a major contribution to the theory of literature, but also a celebration of the extraordinary pleasure of the literary, for reader, writer, student or critic.
Clinical Observations, Plasma Retinol Concentrations, and In Vitro Lymphocyte Functions in Children With Sickle Cell Disease

Background: Children with sickle cell disease (SCD) often have infections, growth deficits, and impaired immunity, problems that also are observed in individuals with a vitamin A deficiency (plasma retinol concentration <20 μg/dL). The goal of this study was to investigate the association between vitamin A, health status, and the in vitro immune function of children with SCD. Methods: Fifty-nine children (40 SS, 11 SC, and 8 Sβthalassemia [Sβthal] hemoglobin genotypes) 9 months to 18 years old were investigated for plasma levels of retinol, retinol binding protein, C-reactive protein, alpha-1-acid glycoprotein, lymphocyte proliferation, and interleukin (IL)-2 activity in supernatant of phytohemagglutinin-treated lymphocytes. Results: The plasma retinol concentrations of children with SCD (mean 57.6 μg/dL, range 4.6-116 μg/dL) were not different from those of 21 normal individuals (mean 62 μg/dL, range 28.7-162 μg/dL). Plasma retinol concentrations did not vary by hemoglobin genotype but were lower in boys than in girls (P < 0.05) and were also lower in children with inflammation (P = 0.1). Seven children (11.9%) (6 HbSS, 1 HbSβ0thal) were vitamin A–deficient, and 9 children (15.3%) had suboptimal vitamin A status (plasma retinol concentration of 20-29 μg/dL). Children with vitamin A deficiency had slightly lower height (P = 0.09) and weight mean percentiles, lymphocyte proliferative responses, and IL-2 activity (P > 0.1), but higher means of C-reactive protein (P = 0.05), pain crisis episodes and inflammation (P = 0.1), and health scores (P > 0.1) than children who were not vitamin A–deficient. Lymphocyte proliferative responses negatively correlated with health score, pain crisis episodes, and blood units received, but positively correlated with retinol binding protein (P < 0.05 to P = 0.1). Conclusion: Identification and correction of suboptimal vitamin A status in children with SCD may improve immunity and attenuate certain health complications associated with this disease.
Dual-Band Folded-Shorted Patch Antenna for Military Search and Rescue Operations and Emergency Communications

There has been a gradual increase in wearable-based applications such as Nike plus, Google glass, Fitbit and smart watches to name a few. In this paper, a dual-band compact folded-shorted patch (FSP) antenna is developed and is operational at 400 MHz and 2.4 GHz for UHF satellite communications and WBAN/WLAN technologies, respectively. Polydimethylsiloxane (PDMS) is used as a flexible substrate for the FSP antenna making it suitable for wearable applications. Moreover, the compactness and durability of this antenna make it appropriate for military search and rescue operations and emergency communications, and the presence of the PDMS substrate makes it resilient to harsh environmental conditions while also providing flexibility for the user.
Nutrition and lipidomic profile in colorectal cancers

Background: Adherence to a healthy diet has been reported to be essential for the primary prevention of colorectal cancer, through a reduction of tissue inflammation, a low concentration of circulating lipoproteins and lower levels of serum cholesterol. Since an altered expression of the fatty acids pattern has been demonstrated to be a crucial event in colorectal carcinogenesis, lipidomic analysis is considered able to identify early diagnostic and prognostic biomarkers of complex diseases such as colorectal cancer. Methods: cell membrane fatty acid profile and serum lipoproteins pattern were evaluated by gas chromatography and electrophoresis method respectively. Results: There is a close association between diet and lipidomic profile in colorectal cancer, both in pre-clinical and clinical studies. A modified serum lipoproteins pattern has been demonstrated to be predominant in intestinal tumors. Conclusions: The study of fatty acids profile in cell membrane and the evaluation of serum lipoproteins subfractions could be useful to have an integrate vision on the interactions between lipids and the pathogenesis of colorectal cancer and to understand the mechanisms of action and the consequences of these interactions on human health status. (www.actabiomedica.it)
One-year parasitological screening of stray dogs and cats in County Dublin, Ireland

Abstract To date, there are no recent studies identifying the prevalence of parasites of human and veterinary importance in dogs and cats in Ireland. The interaction between pets and wildlife species in the environment is an important source of parasite exposure to canids and felines, and one likely to be heightened in the stray animal population. This study aimed to establish the prevalence of endoparasites in unowned dogs and cats in County Dublin, Ireland. Feces from stray dogs (n = 627) and cats (n = 289) entering a rehoming centre were collected immediately after defecation. The main parasitic agents detected were ascarids (15.52 and 30.26%), Cystoisospora (3.27 and 3.69%), Giardia spp. (6.02 and 1.84%) and lungworms (0.64 and 2.08%), in dogs and cats respectively. Animals younger than 3 months of age were more likely to be infected with ascarids (P < 0.001) and Cystoisospora spp. (P = 0.008 and P = 0.014) than older animals. All lungworms were morphologically identified and dogs were infected with Angiostrongylus vasorum (0.48%) and Crenosoma vulpis (0.16%) whereas cats were only infected with Aelurostrongylus abstrusus (2.08%). This represents the first prevalence study of stray animals in Ireland. Data collected will inform the treatment and in addition, the future monitoring and control studies of parasite populations.
TWINs: Two Weighted Inconsistency-reduced Networks for Partial Domain Adaptation

The task of unsupervised domain adaptation is proposed to transfer the knowledge of a label-rich domain (source domain) to a label-scarce domain (target domain). Matching feature distributions between different domains is a widely applied method for the aforementioned task. However, the method does not perform well when classes in the two domains are not identical. Specifically, when the classes of the target correspond to a subset of those of the source, target samples can be incorrectly aligned with the classes that exist only in the source. This problem setting is termed as partial domain adaptation (PDA). In this study, we propose a novel method called Two Weighted Inconsistency-reduced Networks (TWINs) for PDA. We utilize two classification networks to estimate the ratio of the target samples in each class with which a classification loss is weighted to adapt the classes present in the target domain. Furthermore, to extract discriminative features for the target, we propose to minimize the divergence between domains measured by the classifiers' inconsistency on target samples. We empirically demonstrate that reducing the inconsistency between two networks is effective for PDA and that our method outperforms other existing methods with a large margin in several datasets.
Bloodless living donor liver transplantation

Abstract Massive bleeding is often unavoidable during liver transplantation (LT). However, blood transfusions are associated with risks and should be avoided whenever possible. This study compares preoperative factors and outcomes between non-transfusion and transfusion groups to identify variables that could be used to predict bloodless surgery in living donor liver transplantation (LDLT) patients. We conducted a retrospective study of 87 LDLT patients. The group of patients who did not require packed red blood cell (PRBC) transfusion (non-PRBC group, n = 44) was compared with those who did (PRBC group, n = 43). We compared risk factors, fluid management, and outcomes between the groups and identified variables for prediction of transfusion during LDLT. Compared with the PRBC group, the non-PRBC group had a lower model for end-stage liver disease (MELD) score (8.1 ± 1.1 vs 18.2 ± 8.8), international normalized ratio (INR) (1.16 ± 0.1 vs 1.80 ± 0.94), and partial thromboplastin time (PTT) (37.1 ± 6.3 vs 54.1 ± 24.0), but higher hemoglobin (Hb) (13.6 ± 1.6 vs 11.5 ± 2.2) and hematocrit (HCT) (39.1 ± 4.4 vs 32.6 ± 6.0). The non-PRBC group were more likely to receive colloid and albumin but had shorter intensive care unit (ICU) and hospital length of stay. The area under the receiver operative characteristic (ROC) curve of the MELD score was the highest (91%) using a cutoff value of 10.5. Patients without PRBC transfusion during LDLT were in better condition preoperatively and had better outcomes. The MELD score is a significant predictor for PRBC transfusion.
Conference on ‘Targeted approaches to tackling current nutritional issues’ Symposium 2: Developing and using novel health and nutritional biomarkers Gut microbiota and health: connecting actors across the metabolic system

Overweight-related metabolic diseases are an important threat to health in the Western world. Dietary habits are one of the main causative factors for metabolic syndrome, CVD and type 2 diabetes. The human gut microbiota is emerging as an important player in the interaction between diet and metabolic health. Gut microbial communities contribute to human metabolism through fermentation of dietary fibre and the result of intestinal saccharolytic fermentation is production of SCFA. Acetate, propionate and butyrate positively influence satiety, endocrine system, glucose homeostasis, adipogenesis, lipid oxidation, thermoregulation, hepatic gluconeogenesis, endothelial function and gut barrier integrity, and these mechanisms have all been linked to protection from type 2 diabetes, hypertension and cardiovascular health. The gut microbiota is also involved in bile acid metabolism and regulating their cell signalling potential, which has also been shown to modify pathways involved in metabolic health. Similarly, the gut microbiota renders recalcitrant plant polyphenols into biologically active small phenolic compounds which then act systemically to reduce metabolic disease risk. This review summarises how dietary patterns, specific foods and a healthy lifestyle may modulate metabolic health through the gut microbiota and their molecular cross-talk with the host.
Cross‐sectional associations of sex hormones with leucocyte telomere length, a marker of biological age, in a community‐based cohort of older men

Telomeres protect chromosomes from damage, and shorter leucocyte telomere length (LTL) is a marker of advancing biological age. The association between testosterone (T) and its bioactive metabolites, dihydrotestosterone (DHT) and oestradiol (E2) with telomere length, particularly in older men, is uncertain. The study aimed to clarify associations of sex hormones with LTL in older men.