Miracle-dz/UniFAR-FTUs huggingface dataset:
Heavy-Load Eccentric Calf Muscle Training For the Treatment of Chronic Achilles Tendinosis

We prospectively studied the effect of heavy-load eccentric calf muscle training in 15 recreational athletes (12 men and 3 women; mean age, 44.3 7.0 years) who had the diagnosis of chronic Achilles tendinosis (degenerative changes) with a long duration of symptoms despite conventional nonsurgical treatment. Calf muscle strength and the amount of pain during activity (recorded on a visual analog scale) were measured before onset of training and after 12 weeks of eccentric training. At week 0, all patients had Achilles tendon pain not allowing running activity, and there was significantly lower eccentric and concentric calf muscle strength on the injured compared with the noninjured side. After the 12-week training period, all 15 patients were back at their preinjury levels with full running activity. There was a significant decrease in pain during activity, and the calf muscle strength on the injured side had increased significantly and did not differ significantly from that of the noninjured side. A comparison group of 15 recreational athletes with the same diagnosis and a long duration of symptoms had been treated conventionally, i.e., rest, nonsteroidal antiinflammatory drugs, changes of shoes or orthoses, physical therapy, and in all cases also with ordinary training programs. In no case was the conventional treatment successful, and all patients were ultimately treated surgically. Our treatment model with heavy-load eccentric calf muscle training has a very good short-term effect on athletes in their early forties.
Quantitative Phase-Field Simulation of Composition Partition and Separation Kinetics of Nanoscale Phase in Fe-Cr-Al Alloy

Phase separation of the Cr-enriched nanoscale α′ phase in the Fe-38 at. % Cr-10 at. % Al alloy is studied by utilizing phase-field simulation. The partition of elements in the α and α′ phases is clarified with the composition evolution through the α/α′ phase interface, and the separation kinetics is quantitatively investigated by the temporal evolution of the size and volume fraction of the α′ phase. Aluminum partitions into the Fe-enriched α phase and depletes in the α′ phase, and the partition coefficient decreases as the temperature changes from 720 K to 760 K for the steady-state coarsening stage. As the temperature increases, the initial change rate of the volume fraction of the α′ phase is faster, indicating an accelerated phase separation. At the coarsening stage, the average particle distance and coarsening rate constant of the α′ phase increase with increased temperature, and the ratio of the Ostwald ripening is dominating compared with coalescence coarsening. The element partition and kinetics evolution of the α′ phase with temperature are helpful for the morphology and property predication of nanoscale precipitates.
High order edge elements on simplicial meshes

Low order edge elements are widely used for electromagnetic field problems. Higher order edge approximations are receiving increasing interest but their definition become rather complex. In this paper we propose a simple definition for Whitney edge elements of polynomial degree higher than one. We give a geometrical localization of all degrees of freedom over particular edges and provide a basis for these elements on simplicial meshes. As for Whitney edge elements of degree one, the basis is expressed only in terms of the barycentric coordinates of the simplex. Mathematics Subject Classification. 78M10, 65N30, 68U20.
The factors influencing CoP activities and their impact on relationship commitment and individual performance

Purpose – The objective of this study is to identify the factors that affect CoP activation and performance variables obtainable through CoP activities, and to gain greater insight into their relationships and the mechanisms. In particular, this paper intends to illustrate the role of perceived risk factor for the loss of uniqueness of one's own knowledge in terms of their influence on CoP activities. Design/methodology/approach – In this study, the human behaviours were divided into online and offline CoP activities and adopted affirmative affect and social norm from the Triandis model. In addition, the paper considered perceived expectation, perceived risk, and organization support as independent variables. These would accelerate online and offline activities in the community of practice. The paper considered relationship commitment and individual performance in the context of performance evaluations via CoP activities. A structural equation model was developed with research variables and hypotheses. Fi.
Data Content and Exchange in General Practice: a Review

Background: efficient communication of data is inevitable requirement for general practice. Any issue in data content and its exchange among GP and other related entities hinders continuity of patient care. Methods: literature search for this review was conducted on three electronic databases including Medline, Scopus and Science Direct. Results: through reviewing papers, we extracted information on the GP data content, use cases of GP information exchange, its participants, tools and methods, incentives and barriers. Conclusion: considering importance of data content and exchange for GP systems, it seems that more research is needed to be conducted toward providing a comprehensive framework for data content and exchange in GP systems.
Characterization of the Polypeptides Formed in Response to Encephalomyocarditis Virus Ribonucleic Acid in a Cell-Free System from Mouse Ascites Tumor Cells

The polypeptide products synthesized at different times in a cell-free system from Krebs mouse ascites tumor cells in response to the addition of encephalomyocarditis (EMC) virus ribonucleic acid (RNA) were characterized by electrophoresis on polyacrylamide gels and fingerprint analysis of their tryptic peptides. Translation of the EMC RNA genome with time occurred in a nonrandom fashion in these systems, to yield products containing sequences characteristic of both virion capsid polypeptides and EMC-specific polypeptides present only in the infected cell. The molecular weights of the products fell in a series from 20,000 to 140,000 daltons, although occasionally traces of larger polypeptides were also observed. All of the major polypeptides appeared to arise from partial or complete translation of about 60% of the EMC RNA genome. They were not formed by cleavage of a large precursor molecule. It is suggested that they are artifacts generated by premature “termination” of nascent polypeptide chains at preferred sites.
Haptically Straight Lines

In this research, we set out to investigate haptically perceived space. Large deviations with respect to physical space have already been shown to exist. Here, research on haptic space is continued by investigating straight lines constructed by touch. In four experiments, subjects were asked to produce straight lines between two reference markers that were in the horizontal plane at a fixed distance from each other. Each experiment corresponded to a different task: two different interpolation tasks, an intersection task, and a pointing task. Straight lines had an orientation that was approximately frontoparallel. Subjects used both hands; manipulation was unrestricted. Although we found considerable differences between observers, the overall pattern of results showed that haptically straight lines were generally curved away from the observer. However, in one of the interpolation tasks they corresponded to physically straight lines. In addition, the pointing task generally produced larger deviations than the other three tasks. Taken together, the results show that there is no unique definition of the straight line, a conclusion that questions the viability of the concept of haptic space.
Extremely deep Bayesian learning with Gromov's method

We have invented two new Bayesian deep learning algorithms using stochastic particle flow to compute Bayes’ rule. These learning algorithms have a continuum of layers, in contrast with 10 to 100 discrete layers in standard deep learning neural nets. We compute Bayes’ rule for learning using a stochastic particle flow designed with Gromov’s method. Both deep learning and standard particle filters suffer from the curse of dimensionality, and we mitigate this problem by using stochastic particle flow to compute Bayes’ rule. The intuitive explanation for the dramatic reduction in computational complexity is that stochastic particle flow adaptively moves particles to the correct region of d dimensional space to represent the multivariate probability density of the state vector conditioned on the data. There is nothing analogous to this in standard neural nets (deep or shallow), where the geometry of the network is fixed.
Robust state-derivative feedback LMI-based designs for multivariable linear systems

In some practical problems, for instance in the control systems for the suppression of vibration in mechanical systems, the state-derivative signals are easier to obtain than the state signals. New necessary and sufficient linear matrix inequalities (LMI) conditions for the design of state-derivative feedback for multi-input (MI) linear systems are proposed. For multi-input/multi-output (MIMO) linear time-invariant or time-varying plants, with or without uncertainties in their parameters, the proposed methods can include in the LMI-based control designs the specifications of the decay rate, bounds on the output peak, and bounds on the state-derivative feedback matrix K. These design procedures allow new specifications and also, they consider a broader class of plants than the related results available in the literature. The LMIs, when feasible, can be efficiently solved using convex programming techniques. Practical applications illustrate the efficiency of the proposed methods.
A Review of the Federal Government's Health Activities in Response to Asbestos-Contaminated Ore Found in Libby, Montana

Vermiculite ore is a naturally occurring fibrous mineral widely used in various consumer products, such as attic insulation, lawn and garden products, and fireproofing material. While most vermiculite ore and products do not pose a health hazard, the vermiculite mined from Libby, MT was contaminated with naturally occurring asbestos. The federal Agency for Toxic Substances and Disease Registry (ATSDR) has documented a significant number of asbestos-related deaths among Libby residents. Additionally, as part of the ongoing investigation, ATSDR has learned that this contaminated ore was shipped to hundreds of locations around the United States for processing. While the Libby mine is now closed, studies from ATSDR and elsewhere show that people who worked in the Libby mine or vermiculite processing facilities may have been exposed to hazardous levels of asbestos while the facilities were in operation. People who lived or worked near these sites also may have been exposed to asbestos if they came into contact with contaminated vermiculite. Prolonged exposure to asbestos can cause serious and life-threatening health conditions, including asbestosis, lung cancer, and mesothelioma. In response, ATSDR has initiated 10 different activities to help evaluate the potential health effects among Libby residents and populations throughout the United States who might have been exposed to the asbestos-contaminated ore found in Montana. Some of these activities include conducting environmental exposure evaluations, health statistics reviews, community screenings, and disease-specific surveillance. This article presents the various follow-up activities that have been conducted to date by ATSDR and partnering state health departments.
Antimicrobial Efficacy of Selected Natural Products on Microorganisms Isolated from Throat of Patients with Throat Infection

Introduction: Natural products have been used in traditional medicines for treatment of infections due to the antimicrobial activity they exhibit. This study therefore evaluates the efficacy of honey, ginger (Zingiber officinale) and garlic (Allium sativum) extracts on microorganisms isolated from throat of patients with throat infection. Methods: The antibacterial and antifungal efficacy of honey, ginger (Zingiber officinale) and garlic (Allium sativum) extracts was investigated against microorganisms isolated from throats of infected patients at the ENT Department of State Specialist Hospital, Akure, using agar disc diffusion and agar well diffusion technique respectively. Results: Bacteria isolated from patients with throat infection were Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa, and Proteus mirabilis while the fungal isolates were Candida albicans and Candida tropicalis. The antibacterial and antifungal assay results showed that all bacterial isolates were inhibited by honey, garlic and ginger extract. Honey, ginger and garlic showed highest inhibition against P. mirabilis (19.01±0.31 mm), P. aeruginosa (20.20±0.42 mm) and S. aureus (23.00±0.01 mm) respectively also, antifungal assay results showed that all the extracts had antifungal effect on the fungal isolates. The combination of equal concentrations of honey plus garlic showed the highest inhibitory effect on all the test bacteria followed by honey plus ginger then garlic plus ginger while the combination of honey plus garlic had the highest inhibitory effect on Candida albicans (21.63±0.02 mm) but garlic plus ginger combination showed the highest inhibitory effect on Candida tropicalis (21.68±0.04 mm). Conclusion: The result of this study therefore showed that the bacteria and fungi isolated from throat of patients with throats infection demonstrated sensitivity towards the tested samples of honey, garlic and ginger and hence, can serve as effective therapeutic agents in the treatment of throat infections.
Domain State and Temperature Dependence of Pressure Remanent Magnetization in Synthetic Magnetite: Implications for Crustal Remagnetization

Pressure remanent magnetization (PRM) is acquired when a rock is compressed in the presence of a magnetic field. This process can take place in many different environments from impact and ejection processes in space, to burial and subsequent uplifting of terrestrial rocks. In this study, we systematically study the acquisition of PRM at different pressures and temperatures, using synthetic magnetite in four different grain sizes ranging from nearly single‐domain to purely multidomain. The magnitude of the PRM acquired in a 300 μT field is, within error, independent of the domain state of the sample. We propose that the acquisition of a PRM is mainly driven by the magnetostriction of the magnetic material. We further show that compared to a thermal remanent magnetization, the acquisition of PRM in large multidomain grains can be quite efficient, and may represent a significant component of magnetization in low‐temperature–high‐pressure environments.
Low-Density Lipoprotein Receptor–Related Protein Is Decreased in Optic Neuropathy of Alzheimer Disease

Background: Alzheimer disease (AD) is associated with optic nerve degeneration, yet the underlying pathophysiology of this disease and the optic nerve disorder remain poorly understood. Low-density lipoprotein receptor-related protein (LRP) is implicated in the pathogenesis of AD by mediating the transport of amyloid-β (Aβ) out of the brain into the systemic circulation. As a key player in the reaction to central nervous system injury, astrocytes associate with LRP in AD. This study investigates the role of LRP and astrocytes in the pathogenesis of AD optic neuropathy. Methods: To investigate the role of LRP and astrocytes in the pathogenesis of AD optic neuropathy, we conducted immunohistochemical studies on postmortem optic nerves in AD patients (n = 11) and age-matched controls (n = 10) to examine the presence of LRP. Quantitative analyses using imaging software were used to document the extent of LRP in neural tissues. Axonal integrity was assessed by performing immunohistochemistry on the subjects' optic nerves with an antibody to neurofilament (NF) protein. Double-immunofluorescence labeling was performed to investigate whether LRP colocalized with astrocytes, expressing glial fibrillary acidic protein. Results: LRP expression was decreased in AD optic nerves compared to that in controls (P < 0.001). LRP immunoreactivity was observed in the microvasculature and perivascularly in close proximity to the astrocytic processes. Colocalization of LRP in the astrocytes of optic nerves was also demonstrated. The presence of optic neuropathy was confirmed in the AD optic nerves by demonstrating greatly reduced immunostaining for NF protein as compared to controls. Conclusions: The reduction of LRP in the AD degenerative optic nerves supports the hypothesis that LRP may play a role in the pathophysiology of AD optic neuropathy.
ANALISIS PENDAPATAN USAHATANI BAWANG MERAH DI KABUPATEN MAJALENGKA

Penelitin ini bertujuan untuk menganalisis pendapatan usahatani bawang merah di Kabupaten Majalengka. Penelitian ini dilaksanakan di satu Kabupaten sentra produksi bawang merah di Jawa Barat selama tiga musim tanam. Data yang digunakan dalam penelitian ini merupakan data sekunder yang diperoleh dari data penelitian komoditas bawang merah Pusat Kajian Hortikultura Tropika (PKHT) IPB tahun 2015. Pengumpulan data yang dilakukan oleh PKHT dilakukan melalui metode survei dan wawancara langsung dengan responden petani bawang merah dengan bantuan kuesioner. Responden petani bawang merah ditentukan secara purposive . Jumlah data responden yang digunakan dalam penelitian ini sebanyak 37 petani bawang merah di Kabupaten Majalengka. Analisis data yang digunakan adalah deskriftif, analisis pendapatan serta analisis R/C rasio. Hasil analisis menunjukkan bahwa pendapatan usahatani bawang merah disetiap Musim (Musim Hujan, Musim Kemarau I dan Musim Kemarau II) di Kabupaten Majalengka, pendapatan usahatani atas biaya tunai maupun biaya total lebih besar dari nol. Hal ini menunjukkan bahwa usahatani bawang merah dengan tingkat efisiensi teknis yang ada mampu memberikan keuntungan bagi petani. Hasil analisis R/C rasio juga menunjukkan bahwa usahatani di ketiga Musim menguntungkan untuk diusahakan karena nilai R/C rasio atas biaya tunai maupun atas biaya total lebih besar dari satu.
Demand-Supply Mismatches and Stock Market Reaction: Evidence from Excess Inventory Announcements

This paper documents that excess inventory announcements, an indication of demand-supply mismatch, are associated with an economically and statistically significant negative stock market reaction. The results are based on a sample of 276 excess inventory announcements made during 1990--2002. Over a two-day period (the day of the announcement and the day before the announcement) the mean (median) stock market reaction ranges from -6.79% to -6.93% (-4.51% to -4.79%), depending on the benchmark used to estimate the market reaction. The percent of sample firms that experience negative market reaction ranges from 73% to 74%. When excess inventory is at the announcing firm's customers, the market reaction is more negative than when the excess inventory is at the announcing firm. The stock market reaction is less negative for excess inventory announcements made by larger firms but is more negative for firms with higher growth prospects and with higher debt-equity ratios.
Characterization of allergen‐specific monocyte‐derived dendritic cells generated from monocytes by a single‐step procedure: effect on naïve and memory T cells

Background: Dendritic cells are one of the most potent antigen‐presenting cells and when pulsed with allergen can modulate allergen‐specific T‐cell responses. We sought to establish a single‐step method by which to generate allergen‐specific monocyte‐derived dendritic cells (MoDCs).
Relationship between Community Collectivization and Financial Vulnerability of Female Sex Workers in Southern India

Introduction Studies exploring the linkages between financial vulnerabilities and community collectivization of female sex workers (FSWs) are scarce in India despite having potential policy implications. To fill this gap in the literature, this study attempts to understand the financial vulnerabilities among FSWs and assess the relationship between community collectivization and financial vulnerabilities in southern India. Data and Methods Data were drawn from a cross-sectional, behavioral tracking survey (BTS)—2014, conducted among FSWs (N = 2400) in Andhra Pradesh, a southern state of India under the Avahan-India AIDS initiative program. Adjusted odds ratios (AOR) and their 95% confidence intervals (CI) were estimated through multivariate logistic regression, to assess the independent relationships of the degree of community collectivization indicators with financial vulnerability indicators, adjusting for socio-demographic characteristics. Results Most FSWs (87%) reported having either one or more financial vulnerability and nearly one-fifth had a high financial vulnerability. The risk of facing financial vulnerability was significantly lower among FSWs with a high degree of perceived collective efficacy (15% vs 31%; AOR: 0.4; 95% CI: 0.3–0.5) and collective agency (4% vs 21%; AOR: 0.2; 95% CI: 0.1–0.3) as compared to their respective counterparts, after controlling for their individual socio-demographic characteristics. FSWs with a high degree of collective efficacy are also less likely to report different components of financial vulnerability (e.g. income, saving, expenditure, and debt). Conclusion This study finding suggests that community-led interventions such as improving collectivization are promising strategies to address financial vulnerabilities and a path to a sustainable reduction of HIV risk. This study calls for further evidence-based research and measurement of the effects of community-led approaches in addressing the financial vulnerabilities of the key population at risk for HIV.
CHARACTERISATION OF RESPONSE TO PHOSPHINE IN ADULTS OF REPRESENTATIVE STRAINS OF SITOPHILUS ZEAMAIS (MOTSCH.), SITOPHILUS ORYZAE (L.) AND RHYZOPERTHA DOMINICA (F.) FROM CHINA

The effects of exposure period and phosphine concentration were quantified in adults of representative strains of Sitophilus zeamais (Motsch.), Sitophilus oryzae (L.) and Rhyzopertha dominica (F.) from China. All three species are major pests of stored grain in China. Although phosphine resistance is common in Chinese S. oryzae and R. dominica, with some very resistant populations, it is not present in Chinese S. zeamais. Therefore, the study was undertaken on a susceptible strain of S. zeamais, a strong resistant strain of S. oryzae, and a strong resistant strain of R. dominica. Adults were fumigated at a range of concentrations for periods of 20-144 h at 25oC and 70% r.h. The data fitted the probit model well except for data from the Chinese strains of S. oryzae and R. dominica at 20 h, where the LC 99.9 values were much greater than the highest test concentrations. The LC 50 and LC 99.9 tended to decrease with increasing exposure period, and the effects of concentration (C) and time (T) could be described for all strains by the equation C n T = K. Time and concentration were equally important dosage factors for the susceptible strain of S. zeamais (n ≅ 1), but time was a more important dosage factor than concentration for the resistant strains of S. oryzae and R. dominica (n < 1).