Miracle-dz/UniFAR-FTUs huggingface dataset:
Risk of cardiovascular disease in Chinese patients with rheumatoid arthritis: A cross-sectional study based on hospital medical records in 10 years

Objective Though the risk of cardiovascular disease (CVD) in rheumatoid arthritis (RA) has been established in Western population, little is known about the risk in Chinese people with RA. Our objective was to estimate the risk of CVD in Chinese people with RA using hospital medical records data. Methods The inpatients medical record database 2005–2015 of Sichuan provincial people’s hospital was examined. All individuals with a primary diagnosis of RA were included as cases, and those of osteoarthritis (OA) were included as controls, which consisted of the unmatched dataset. Then, RA cases and OA controls were matched by sex and age at 1:1 ratio, forming the matched dataset. The morbidity of CVD (including ischemia heart disease (IHD), congestive heart failure (CHF), et al), stroke and arthrosclerosis were extracted from the database, so as the demographic data and comorbidities related to CVD. Multiple logistic regression analysis was used to estimate the risk of CVD in RA adjusted for demographics and comorbidities using the unmatched dataset. Sensitivity analysis was conducted 1) considering interaction terms between RA and comorbidities, and 2) using multivariable conditional logistic regression for the matched dataset. Results The unmatched dataset comprised of 1824RA cases and 1995 OA controls and the matched dataset comprised of 1022 pairs of sex and age matched RA and OA patients. RA exhibited increased odds of prevalent CVD compared with OA, and the adjusted ORs (95%CIs) for CVD, stroke, IHD, CHF, and atherosclerosis were1.86(1.42–2.43), 1.11(0.71–1.74), 1.47(0.97–2.24), 2.09(1.03–4.22), and 2.49 (1.97–3.13), respectively, and was 2.26 (1.29–3.96)for IHD further adjusted for interaction term. The matched dataset analysis found similar results. Conclusions Chinese people with RA were approximated 2 times more likely to have CVD, IHD, CHF and atherosclerosis compared with those with OA. The findings justified the need of further longitudinal study to establish the causal-relationship between RA and CVD and to estimate the precise risk in this population.
Reference intervals of embryos/fetuses heart rate between 6 and 14 weeks of pregnancy

Abstract Objective: To determine reference intervals for the embryos/fetuses heart rate (HR) between 6 and 14 weeks of pregnancy. Methods: A retrospective cross-sectional study was carried in a single center with singleton pregnancies of embryos/fetuses with a crown-rump length (CRL) between 5 and 85 mm. The HR was assessed by real time M-mode or spectrum Doppler ultrasound. To evaluate the correlation between embryo/fetal HR and CRL, polynomial equations were calculated, with adjustment by the determination coefficient (R2). Results: A total of 5867 pregnancies were assessed. The mean gestational age was 10.37 ± 2.12 weeks. The mean maternal age was 26.41 ± 6.78 years. The mean embryo/fetal HR (bpm) for the CRL (mm) intervals 5├15; 15├25; 25├35; 35├45; 45├55; 55├65; 65├75; 75├85 was 145.1 ± 18.7; 167.2 ± 10.1; 166.9 ± 8.7; 165.5 ± 6.9; 162.2 ± 6.8; 159.2 ± 6.4; 157.1 ± 6.4; 154.9 ± 7.3; respectively. The following third-order equation best represented the correlation between embryo/fetal HR and CRL: HR = 119.25 + 3.596*CRL-0.07954*CRL2 + 0.00051*CRL3 (R2 = 0.36). Conclusion: Reference intervals of HR in embryos/fetuses in a large sample were determined. These reference intervals can be used in high-risk early pregnancy losses.
Multilocular Cystic Nephroma: A Systematic Literature Review of the Radiologic and Clinical Findings.

OBJECTIVE The objective of our study was to systematically summarize the published evidence of demographic, clinical, diagnostic imaging, and therapeutic characteristics of patients with multilocular cystic nephroma (MLCN). CONCLUSION Cross-sectional imaging evaluation is important for suggesting the diagnosis of MLCN but has several limitations. The number of radical nephrectomies reported for MLCN encourages discussion concerning the utility of percutaneous presurgical biopsy and frozen-section intraoperative biopsy as a more conservative diagnostic approach.
EFFECTS OF DIETARY THREONINE LEVEL, METHIONINE SOURCES, SEX OF BROILER CHICKS AND THEIR INTERACTIONS ON CARCASS TISSUE DISTRIBUTION AND CHEMICAL COMPOSITION

A total sum of 180 Hubbard broilers chicks (46.9 ± 2.5 g) at one-day-old were used, weighed and divided into six treatments of three replicates each to investigate effects of using two levels of amino acid threonine (T) being (0.0 or 1.0 g/ kg diet) and three different methionine sources: DLmethionine (DLM), acid liquid methionine (ALM) or methionine hydroxy-analogue-calcium salt (MHA) in 2 x 3 factorial design on carcass tissue weight distribution and chemical composition for both male and female broiler chicks, fed corn-soybean meal based diets. Results obtained declared that skin and subcutaneous fat percentages of carcass parts were not altered by neither different dietary treatments nor bird sex. Also, distribution of both muscles and bones was not altered by different dietary treatments as male and female chicks appeared similar, except for muscles percentages of breast and drumstick where, males recoded significantly higher values than female chickens. Additionally, all parameters of tibia bone measurements (tibia length, tibia width, tibia Seedor index (SI) and tibia Robusticity index (RI)) were not significantly affected by different dietary treatments, while male chickens had a significant higher figures (tibia length, width, (SI) and dry tibia weight percentage (DTW %)) than female chickens. Data of chemical composition of both tibia bone and breast meat were presented insignificant effect of either different dietary treatments, or bird sex. While most of studied parameters showed insignificant response due to interactions between threonine levels (T), methionine sources (M) and sex of birds (S). According to results obtained, it would be stated that interactions between dietary threonine (T) supplementation, methionine (M) sources and sex (S), for nearly all studied parameters, were insignificant.
Detection of Oxytetracycline Residues in Honey Samples Using ELISA and HPLC Methods

Background: Honey is being used as an ingredient in many foods, pharmaceuticals and cosmetics than ever before, so honey testing has become essential to maintaining its healthful characteristics and protecting public health. This study was designed to investigate the occurrence of oxytetracycline residue in honey samples. A number of 145 honey samples were collected from Ardabil provinces (Northwest region of Iran). ELISA and HPLC were used to qualify and quantify the contamination of the honey samples with oxytetracycline. The ELISA assay showed that out of 145 samples, 34 samples were positive for oxytetracycline residue. ELISA analyses demonstrated that the minimum and maximum level of oxytetracycline residue was 5.32 and 369.1ng/g respectively. HPLC analyses confirmed the ELISA findings, although the level of oxytetracycline which detected in honey samples using HPLC method was remarkably (P<0.05) lower than that of which detected by ELISA. Considering the relatively high contamination level of foods of animal origin with oxytetracycline and their high levels of consumption, it is likely that consumers experience a high risk of exposure to drug residues, especially through honey bees. A R T I C L E I N F O A B S T R A C T
Mutual Influences Between Parental Psychological Distress and Alcohol Use and Child Problem Behavior in a Cohort of Urban African Americans

Parental psychological distress, parental alcohol involvement, and child/adolescent behavior problems frequently occur together with deleterious effects on individuals and families. Extant evidence suggests that parental and child problems are related; however, less is known about the patterns and directions of their relationships over time, particularly among African Americans. This study examined mutual influences between parental psychological distress and alcohol use, and child/adolescent problem behavior over a 10-year period (N = 459), using data from a prospective cohort study of urban African Americans. Using structural equation modeling, we found statistically significant effects between young adult parents’ alcohol use and later adolescent problem behavior, as well as child problem behavior and parental alcohol use 10 years later, even after taking into account potential extraneous influences. Findings also demonstrated continuity in parental and child behaviors over time, and several contemporaneous associations. These findings have potential implications for intervention planning among African American families.
Does haptic feedback change the way we view touchscreens in cars?

Touchscreens are increasingly being used in mobile devices and in-vehicle systems. While the usability benefits of touchscreens are acknowledged, their use places significant visual demand on the user due to the lack of tactile and kinaesthetic feedback. Haptic feedback is shown to improve performance in mobile devices, but little objective data is available regarding touchscreen feedback in an automotive scenario. A study was conducted to investigate the effects of visual and haptic touchscreen feedback on driver visual behaviour and driving performance using a simulated driving environment. Results showed a significant interaction between visual and haptic feedback, with the presence of haptic feedback compensating for changes in visual feedback. Driving performance was unaffected by feedback condition but degraded from a baseline measure when touchscreen tasks were introduced. Subjective responses indicated an improved user experience and increased confidence when haptic feedback was enabled.
Lernstrategien im Fach Englisch

Lernstrategien sind geistige Aktivitaten, die mit dem Ziel des Lernens, Verstehens und Wissenserwerbs mehr oder weniger bewusst eingesetzt werden. Neben allgemeinen Lernstrategien, die grundlegende kognitive, metakognitive und ressourcenbezogene Aktivitaten umfassen spielen bereichsspezifische Lernstrategien eine wichtige Rolle. Dies gilt in besonderem Mase fur das Lernen von Fremdsprachen, das in den letzten Jahren zum Gegenstand der Lernstrategie-Forschung geworden ist. Fur das Fremdsprachenlernen sinnvolle Strategien umfassen unter anderem gezielte Bemuhungen, die Fremdsprache moglichst oft und systematisch einzusetzen, mit fehlenden Informationen (z.B. nicht bekannten Bedeutungen) umzugehen oder Lerngelegenheiten zu nutzen. Diese Strategien sind Gegenstand des Strategy Inventory for Language Learning (SILL), einem der bekanntesten Fragebogeninstrumente in diesem Bereich. (DIPF/Orig.)
Analysis of “Comparison an Electronic Glycemic Management System Versus Provider Managed Subcutaneous Basal Bolus Insulin Therapy in the Hospital Setting”

Safety and efficacy of a nurse-directed electronic glycemic management system (eGMS) in comparison to basal-bolus subcutaneous insulin therapy managed by providers has been evaluated recently by Aloi et al. They included 993 non–critically ill patients across 9 different hospitals in a retrospective observational crossover study and compared mean blood glucose, number of hypoglycemic events <40 mg/dl and <70 mg/dl and the percentage of blood glucose in target (140-180 mg/dl) before, during and after the use of eGMS. Conclusion was that eGMS can lead to better glycemic control with less hypoglycemic events compared to provider managed basal-bolus insulin therapy (before and after eGMS). Although some limitations exist, the authors made a strong case that eGMS has positive impact on glycemic control in hospitalized patients with diabetes.
Validity and Reliability Analysis of Turkish Version of Childhood Autism Rating Scale 2

Method: 96 children and adolescents aged between 4-18, (48 diagnosed with pervasive developmental disorder (PDD) and 48 diagnosed with mental disability (MD) and developmental delay based on DSM-IV-TR criteria) were included in the study. In order to consider the reliability analysis of the Turkish Form of the scale, Cronbach’s alpha values as internal consistency indicator, and inter-rater reliability and test-retest reliability were calculated. Principal components analysis and Varimax rotation were used in order to determine factors. The scale was compared with the Autism Behavior Checklist and Clinical Global Impression-Severity of Illness. The most appropriate cut-off point was determined for CARS-TF by conducting ROC analysis.
Nevirapine-selected mutations Y181I/C of HIV-1 reverse transcriptase confer cross-resistance to stavudine

Stavudine administration did not increase the frequency of Y181I/C reverse transcriptase (RT) mutations in non-nucleoside reverse transcriptase inhibitor (NNRTI)-treated patients. However, recombinant Y181C HIV-1 showed reduced stavudine susceptibility with respect to both recombinant wild-type and K103N HIV-1 strains. In addition, recombinant Y181I RT enzyme showed reduced susceptibility to stavudine with respect to both wild-type and K103N RT. A previously unnoticed role of Y181I/C RT changes selected by nevirapine or other NNRTI in determining stavudine resistance is documented.
Generalized multiple Dirichlet series and generalized multiple polylogarithms

where t is a complex variable. By Assumption I, we see that the series (1.3) is convergent when <t < 0. We further assume the following: (Assumption II ) ψ(s) can be continued analytically to the whole complex plane C, and holomorphic for all s ∈ C. In any fixed strip σ1 ≤ σ ≤ σ2, ψ(s; u) is uniformly convergent to ψ(s) as u → 1 + 0. Furthermore there exists a certain θ0 = θ0(σ1, σ2) ∈ R with 0 ≤ θ0 < π/2 such that ψ(s;u) = O ( eθ0|τ | ) as |τ | → ∞.
Cheap Talk with Two Audiences: An Experiment

In this paper we experimentally test strategic information transmission between one informed and two uninformed agents in a cheap-talk game. We find evidence of the "disciplining" effect of public communication as compared to private; however, it is much weaker than predicted by the theory. Adding a second receiver naturally increases the complexity of strategic thinking when communication is public. Using the level-k model, we exploit the within subject design to show how individuals decrease their level-k in public communication. Surprisingly, we find that individuals become more sophisticated when they communicate privately with two receivers rather than one.
Exercise in End‐Stage Renal Disease

This article will outline the clinical reasoning for exercise counseling in end‐stage renal disease (ESRD) patients and give healthcare providers detailed information on the different programs that can be implemented in this population according to patients’ specific needs. End‐stage renal disease patients often have other health problems that can be improved by participation in regular exercise programs. Research accumulated during the last 30 years on exercise for the ESRD population supports its numerous beneficial effects including those on cardiovascular capacity, sarcopenia, and health‐related quality of life. We describe the different types of exercise, aerobic and resistance programs (including their frequency, intensity and progression) that are recommended for the ESRD population, as well as the potential goals of each program. Groups with special needs among the ESRD population are considered, as well as safety, potential adverse events, and adherence to exercise programs. Finally, recommendations for future researches are highlighted.
The Surgical Relations of the Levator Palpebrae Superioris Muscle

We conducted a cadaver study of the levator palpebrae superioris muscle to examine several areas of interest that have been reported in the current medical literature. A very strong intermuscular fascia exists between the levator and superior rectus muscles; it is unlikely that a superior rectus bridle suture could pull them apart during cataract surgery. The superior transverse ligament of Whitnall functions to check the posterior movement of the levator; it provides longitudinal support to the resected levator, but does not act as a vertical fulcrum.
In Flight Evaluation of Active Inceptor Force-Feel Characteristics and Handling Qualities

The effect of inceptor feel-system characteristics on piloted handling qualities has been a research topic of interest for many years. Most of the research efforts have focused on advanced fly-by-wire fixed-wing aircraft with only a few studies investigating the effects on rotorcraft. Consequently, only limited guidance is available on how cyclic force-feel characteristics should be set to obtain optimal handling qualities for rotorcraft. To study this effect, the U.S. Army Aeroflightdynamics Directorate working with the DLR Institute of Flight Systems in Germany under Task X of the U.S. German Memorandum of Understanding have been conducting flight test evaluations. In the U.S., five experimental test pilots have completed evaluations of two Mission Task Elements (MTEs) from ADS-33E-PRF and two command/response types for a matrix of center-stick cyclic force-feel characteristics at Moffett Field. In Germany, three experimental test Pilots have conducted initial evaluations of the two MTEs with two command/response types for a parallel matrix of side-stick cyclic force-feel characteristics at WTD-61 in Manching. The resulting data set is used to correlate the effect of changes in natural frequency and damping ratio of the cyclic inceptor on the piloted handling qualities. Existing criteria in ADS-33E and a proposed Handling Qualities Sensitivity Function that includes the effects of the cyclic force-feel characteristics are also evaluated against the data set and discussed.
Impulsive synchronization for uncertain delayed complex dynamical networks with minimal coupling strength

This paper investigates the impulsive synchronization problem of complex dynamical network system (CDNs) with uncertainty and coupling time-varying delay. The aim is to design distributed impulsive controllers with minimum necessary coupling strength. A time-varying Lyapunov function based method is proposed to find the synchronization condition for the impulsively controlled CDNs. By utilizing a convex combination technique, the derived synchronization condition is expressed in terms of linear matrix inequalities (LMIs). Then, an optimization algorithm is proposed to design the distributed impulsive controller with minimum coupling strength. Finally, an example is presented to illustrate the effectiveness of the theoretical results.
Evidence of Validity for the Foot and Ankle Ability Measure (FAAM)

Background: There is no universally accepted instrument that can be used to evaluate changes in self-reported physical function for individuals with leg, ankle, and foot musculoskeletal disorders. The objective of this study was to develop an instrument to meet this need: the Foot and Ankle Ability Measure (FAAM). Additionally, this study was designed to provide validity evidence for interpretation of FAAM scores. Methods: Final item reduction was completed using item response theory with 1027 subjects. Validity evidence was provided by 164 subjects that were expected to change and 79 subjects that were expected to remain stable. These subjects were given the FAAM and SF-36 to complete on two occasions 4 weeks apart. Results: The final version of the FAAM consists of the 21-item activities of daily living (ADL) and 8-item Sports subscales, which together produced information across the spectrum ability. Validity evidence was provided for test content, internal structure, score stability, and responsiveness. Test retest reliability was 0.89 and 0.87 for the ADL and Sports subscales, respectively. The minimal detectable change based on a 95% confidence interval was ±5.7 and ±-12.3 points for the ADL and Sports subscales, respectively. Two-way repeated measures ANOVA and ROC analysis found both the ADL andSports subscales were responsive to changes in status (p < 0.05). The minimal clinically important differences were 8 and 9 points for the ADL and Sports subscales, respectively. Guyatt responsive index and ROC analysis found the ADL subscale was more responsive than general measures of physical function while the Sports subscale was not. The ADL and Sport subscales demonstrated strong relationships with the SF-36 physical function subscale (r = 0.84, 0.78) and physical component summary score (r = 0.78, 0.80) and weak relationships with the SF-36 mental function subscale (r = 0.18, 0.11) and mental component summary score (r = 0.05, −0.02). Conclusions: The FAAM is a reliable, responsive, and valid measure of physical function for individuals with a broad range of musculoskeletal disorders of the lower leg, foot, and ankle.
Cells meeting our immunophenotypic criteria of endothelial cells are large platelets

Circulating endothelial cells (CEC) are shed from damaged vasculature, making them a rational choice to serve as surrogate marker for vascular damage. Currently, various techniques and CEC definitions are in use, and their standardization and validation is needed. A flow cytometric single platform assay defining CEC as forward light scatter (FSC)low‐to‐intermedate, sideward light scatter (SSC)low, CD45−, CD31++ and CD146+ is a promising approach to enumerate CEC because of its simplicity (Mancuso et al., Blood 2001;97:3658–3661). Here, we set out to confirm the endothelial nature of these cells.
Success in NCLEX-RN: identifying predictors and optimal timing for intervention.

This ex post facto study was designed to identify predictors of success in the NCLEX-RN and determine the optimal point in time for identifying students at risk. The convenience sample consisted of 407 graduates of an integrated, upper division, baccalaureate nursing program, 1984-1987. Prematriculation (total lower division GPA, science GPA, type of lower division College, age, and sex), junior year (three Nursing theory course grades) and pre graduation variables (three senior year nursing theory course grades and Mosby ASSESSTEST) were analyzed for predictive value. Nursing theory courses at the junior and senior year and the Mosby ASSESSTEST strongly correlated (p less than .0001) with NCLEX performance. Discriminant analysis enabled successful classification of 62% of the sample at prematriculation, 81% at the end of the junior year, and 86% at the end of the senior year. The study indicates that students at high risk can be identified at the end of the junior year so that enrichment and support programs can be introduced at that time.