Miracle-dz/UniFAR-FTUs huggingface dataset:
Enhanced dual-path compensated amplifier for driving large capacitive load

This paper presents an improved amplifier compensation scheme for driving large capacitive loads. The dual-path compensated amplifier topology requires two parallel high speed paths for signal propagation and offers better performances than previously reported compensation schemes. The goal of this work was to improve this type of architecture in order to achieve lower power consumption, bandwidth extension and slew rate improvement, while reducing the compensation capacitors size and, therefore, the overall chip area.
The Drama of Doctrine: A Canonical-Linguistic Approach to Christian Theology

Observing a strange disappearance of doctrine within the church, Kevin Vanhoozer argues that there is no more urgent task for Christians today than to engage in living truthfully with others before God. He details how doctrine serves the church--the theater of the gospel--by directing individuals and congregations to participate in the drama of what God is doing to renew all things in Jesus Christ. Taking his cue from George Lindbeck and others who locate the criteria of Christian identity in Spirit-led church practices, Vanhoozer relocates the norm for Christian doctrine in the canonical practices, which, he argues, both provoke and preserve the integrity of the church's witness as prophetic and apostolic.
Functions of synapsins in corticothalamic facilitation: important roles of synapsin I

The synaptic vesicle associated proteins synapsin I and synapsin II have important functions in synaptic short‐term plasticity. We investigated their functions in cortical facilitatory feedback to neurons in dorsal lateral geniculate nucleus (dLGN), feedback that has important functions in state‐dependent regulation of thalamic transmission of visual input to cortex. We compared results from normal wild‐type (WT) mice and synapsin knockout (KO) mice in several types of synaptic plasticity, and found clear differences between the responses of neurons in the synapsin I KO and the WT, but no significant differences between the synapsin II KO and the WT. These results are in contrast to the important role of synapsin II previously demonstrated in similar types of synaptic plasticity in other brain regions, indicating that the synapsins can have different roles in similar types of STP in different parts of the brain.
Effect of Replacement of Wheat Straw with Maize Cobs with or without Physico- Chemical Treatment on Degradation of Dry Matter, Truly Digestible Organic Matter and Production of Microbial Biomass of Composite Ration In Vitro using Goat Rumen Liquor

This study was carried out to investigate the effect of replacement of wheat straw by different levels of maize cobs in composite ration on in vitro degradation of dry matter, truly digestible organic matter and production of microbial biomass in order to determine its level of supplementation in ruminant ration. Wheat straw was replaced by maize cobs @ 0, 10, 20, 30, 40, 50 and 100% level to formulate composite rations. The different formulae of composite rations were used for in vitro gas production studies using goat rumen liquor with wheat straw. In physical treatment only soaking was done while under chemical treatment application of urea, molasses and combination of both urea and molasses were applied before conducting in vitro studies using goat rumen liquor. Proximate composition, fiber fractionation and calcium and phosphrous content of all the composite rations were estimated. The in vitro degradability of maize cobs based diets is better than wheat straw based composite ration. There was no significant (P>0.05) improvement in per cent IVDMD of maize cob based diet by water soaking irrespective of the soaking period, however, a significant (P<0.05) improvement in in vitro degradation parameters were observed with urea-ammoniation of maize cobs. No benefit of molasses treatment either in isolation or in combination was observed over maize cobs utilization as compared to urea-ammoniated maize cobs. It is concluded that feeding value of maize cobs is similar to wheat straw as indicated by IVDMD while urea-ammoniation appears to be the ‘treatment of choice’ for improving nutritive value of maize cobs.
k-Nearest Neighbor Neural Network Models for Very Short-Term Global Solar Irradiance Forecasting Based on Meteorological Data

This paper proposes a novel methodology for very short term forecasting of hourly global solar irradiance (GSI). The proposed methodology is based on meteorology data, especially for optimizing the operation of power generating electricity from photovoltaic (PV) energy. This methodology is a combination of k-nearest neighbor (k-NN) algorithm modelling and artificial neural network (ANN) model. The k-NN-ANN method is designed to forecast GSI for 60 min ahead based on meteorology data for the target PV station which position is surrounded by eight other adjacent PV stations. The novelty of this method is taking into account the meteorology data. A set of GSI measurement samples was available from the PV station in Taiwan which is used as test data. The first method implements k-NN as a preprocessing technique prior to ANN method. The error statistical indicators of k-NN-ANN model the mean absolute bias error (MABE) is 42 W/m2 and the root-mean-square error (RMSE) is 242 W/m2. The models forecasts are then compared to measured data and simulation results indicate that the k-NN-ANN-based model presented in this research can calculate hourly GSI with satisfactory accuracy.
Survival Rates of Tropical and Temperate Passerines: A Trinidadian Perspective

Mark‐recapture data collected using mist nets over a 10‐yr period in Trinidad were used to estimate adult survival rates for 17 species of forest passerines. Trinidadian survival rates (mean 65%, range 45%—85%) were significantly higher than published estimates for European (mean survival 52%, range 32%–71%) and North American (mean survival 53%, range 29%–63%) passerines of similar body size (equivalent to 45% higher mean life expectancy in Trinidad). These findings were confirmed after controlling for phylogeny using a method of independent contrasts. Transient and/or young birds were an important feature of the Trinidad data, and studies that fail to allow for the presence of such birds risk underestimating adult survival. This study lends support to the hypothesis that avian survival rates are higher in the humid tropics, although the magnitude of the difference may be smaller than previously suggested.
Long‐Term Results of Free Vascularized Fibular Graft: A Clinical and Radiographic Evaluation

Seven patients who had free vascularized fibular grafts for bone defects >6 cm (mean, 16.6 cm) were studied retrospectively. There were 5 cases of tumor, 1 pseudoarthrosis, and 1 chronic osteomyelitis. The average followup period was 9.2 years (range, 5.2–11.3 years). Of the 5 patients with grafts to the lower limb, 1 showed a 30% reduction in bone width as seen on anteroposterior radiographs, whereas 4 patients had increases ranging from 44% to 100% (average, 66%). There were 4 graft stress fractures, of which 1 developed eventual shortening of 2.5 cm. One graft had pseudoarthrosis involving the proximal graft-host junction that required secondary procedures with autogenous cancellous bone grafting, with eventual limb-length shortening of 5 cm. All other graft-recipient junctions healed primarily. The Functional Evaluation Score ranged from 60% to 100% of normal function (mean, 85%). Three patients were able to return to sports participation. Mild weakness of the extensor hallucis longus in the donor limb was observed in 5 patients. Two patients had mild loss of plantar flexion, and 4 had limitation of dorsiflexion affecting the ankle of the donor limb.
Children's Key Concerns: Piloting a Qualitative Approach to Understanding Their Experience of Mental Health Care

This article reports the piloting of an approach to apply the principles of child involvement to service experience research. The approach aimed to systematically explore the service concerns of children who had received mental health care. Eleven children who had previously attended mental health services took part in focus groups to discuss their experience. Thematic content analysis of transcribed interviews revealed 13 themes that potentially could help to identify children's key concerns and clarify the notion of child-centred care. The themes suggested the potential importance of children's expectations about therapy, and their concerns relating to the process, content and outcome may be important to their experience of care. The possible implications for child-centred clinical practice and service provision are discussed.
Evaluation of exogenous siRNA addition as a metabolic engineering tool for modifying biopharmaceuticals

Traditional metabolic engineering approaches, including homologous recombination, zinc‐finger nucleases, and short hairpin RNA, have previously been used to generate biologics with specific characteristics that improve efficacy, potency, and safety. An alternative approach is to exogenously add soluble small interfering RNA (siRNA) duplexes, formulated with a cationic lipid, directly to cells grown in shake flasks or bioreactors. This approach has the following potential advantages: no cell line development required, ability to tailor mRNA silencing by adjusting siRNA concentration, simultaneous silencing of multiple target genes, and potential temporal control of down regulation of target gene expression. In this study, we demonstrate proof of concept of the siRNA feeding approach as a metabolic engineering tool in the context of increasing monoclonal antibody (MAb) afucosylation. First, potent siRNA duplexes targeting fut8 and gmds were dosed into shake flasks with cells that express an anti‐CD20 MAb. Dose response studies demonstrated the ability to titrate the silencing effect. Furthermore, siRNA addition resulted in no deleterious effects on cell growth, final protein titer, or specific productivity. In bioreactors, antibodies produced by cells following siRNA treatment exhibited improved functional characteristics compared to antibodies from untreated cells, including increased levels of afucosylation (63%), a 17‐fold improvement in FCgRIIIa binding, and an increase in specific cell lysis by up to 30%, as determined in an Antibody‐Dependent Cellular Cytoxicity (ADCC) assay. In addition, standard purification procedures effectively cleared the exogenously added siRNA and transfection agent. Moreover, no differences were observed when other key product quality structural attributes were compared to untreated controls. These results establish that exogenous addition of siRNA represents a potentially novel metabolic engineering tool to improve biopharmaceutical function and quality that can complement existing metabolic engineering methods. © 2013 American Institute of Chemical Engineers Biotechnol. Prog. , 2013 American Institute of Chemical Engineers Biotechnol. Prog. , 29: 415–424, 2013
Cell wall monoglycine cross-bridges and methicillin hypersusceptibility in a femAB null mutant of methicillin-resistant Staphylococcus aureus

The femAB operon is involved in the formation of the characteristic pentaglycine side chain of the staphylococcal peptidoglycan. Allele replacement of the femAB operon with the tetracycline resistance determinant tetK in a methicillin-resistant Staphylococcus aureus strain resulted in impaired growth, methicillin hypersusceptibility, and lysostaphin resistance. The usual pentaglycine cross-bridges were replaced by monoglycine bridges exclusively, and cross-linking of the peptidoglycan strands was drastically reduced. Complementation of the femAB null mutant by either femA or femAB resulted in the extension of the cross-bridges to a triglycine or a pentaglycine, respectively. This finding suggests that FemA is responsible for the formation of glycines 2 and 3, and FemB is responsible for formation of glycines 4 and 5, of the pentaglycine side chain of the peptidoglycan precursor. Moreover, it can be deduced that addition of the first glycine must occur by a femAB-independent mechanism.
Clinical Predictors Associated With Duration of Repetitive Transcranial Magnetic Stimulation Treatment for Remission in Bipolar Depression: A Naturalistic Study

Repetitive transcranial magnetic stimulation (rTMS) has been widely tested and shown to be effective for unipolar depression. Although it has also been investigated for bipolar depression (BD), there are only few rTMS studies with BD. Here, we investigated 56 patients with BD who received rTMS treatment until remission (defined as Hamilton Depression Rating Scores ≤7). We used simple and multiple logistic regressions to identify clinical and demographic predictors associated with duration of treatment (defined as <15 vs. >15 rTMS sessions). Age, refractoriness, number of prior depressive episodes, and severe depression at baseline were associated with a longer rTMS treatment. In the multivariate analysis, refractoriness (likelihood ratio (LR) = 4.33; p < 0.01) and baseline severity (LR = 0.18, p < 0.01) remained significant predictors. Our preliminary study showed that, in remitted patients, refractoriness and severity of index episode are associated with the need of a longer rTMS treatment; providing preliminary evidence of important factors associated with rTMS parameters adjustment.
Generation automatique d'algorithmes de filtrage a partir de specifications declaratives : le systeme gap

Le filtrage est un mecanisme qui permet de determiner les regles candidates au declenchement a chaque cycle du moteur en eliminant les regles dont au moins une condition n'est pas satisfaite. L'instanciation des regles n'est alors effectuee que sur les regles qui ont franchi l'etape de filtrage avec succes. Dans les systemes classiques, les moyens mis en uvre pour realiser le filtrage sont simples. Cela est du principalement a la nature des conditions qui sont autorisees en premisses de regles. En regle generale, ces conditions decrivent de maniere generique les elements de la memoire de travail. Nous nous sommes interesses a la generation automatique d'algorithmes de filtrage a partir d'une specification declarative. Dans notre etude, nous avons considere des conditions de regles complexes qui sont des formules de la logique des predicats du premier ordre avec les quantificateurs existentiels et universels dans n'importe quel ordre. Notre methode de generation automatique des algorithmes de filtrage repose sur la differentiation ensembliste que nous avons definie en tenant compte a la fois des aspects qualitatifs et quantitatifs. La differentiation ensembliste qualitative nous permet d'eliminer les directions vers lesquelles les ensembles ne peuvent varier. Dans la generation des algorithmes de filtrage, ces informations de nature qualitative nous ont permis de conclure immediatement dans certaines situations. La connaissance des differentielles qualitatives des ensembles nous evite egalement de calculer des differentielles quantitatives d'expressions ensemblistes composees qui s'averent vides. Nous avons developpe un prototype, le systeme gap. Gap se compose d'un module de generation et d'un module de reecriture. Ce dernier permet de simplifier les expressions contenues dans les algorithmes engendres
Bank Capital Regulation and Endogenous Shadow Banking Crises

We study the macroeconomic effects of bank capital requirements in an economy with two banking sectors. Banks are connected through a wholesale funding market. Anticipated banking crises occur endogenously in the form of self-fulfilling wholesale funding rollover crises. Retail bank capital requirements can reduce the frequency and severity of banking crises. Tightening retail bank capital requirements increases the size and leverage of the shadow banking sector through a novel channel that works through the anticipation of banking crises. A policy which corrects this spillover is more than twice as effective in reducing the frequency and severity of banking crises.
Efficient generation of 
 T2* ‐weighted contrast by interslice echo‐shifting for human functional and anatomical imaging at 9.4 Tesla

Standard gradient‐echo sequences are often prohibitively slow for T2* ‐weighted imaging as long echo times prolong the repetition time of the sequence. Echo‐shifting offers a way out of this dilemma by allowing an echo time that exceeds the repetition time. The purpose of this work is to present a gradient‐echo sequence that is optimized for multislice T2* ‐weighted imaging applications by combining echo‐shifting with an interleaved slice excitation order.
Proton magnetic resonance spectroscopy-guided biopsy for cerebral glial tumors.

BACKGROUND AND PURPOSE Although application of proton magnetic resonance (MR) spectroscopy in the diagnosis of brain tumors has been reported, the role of this technique as guidance for targeting biopsy of brain tumors is not well established. The usefulness and limitations of predicting tumor proliferative activity and pathological grading of brain gliomas based on samples obtained from proton MR spectroscopy-guided stereotactic biopsy also remains unclear. The purpose of this study was to evaluate the usefulness of single-voxel MR spectroscopy-guided stereotactic biopsy for cerebral gliomas and to correlate the findings of MR spectroscopy with proliferative activity (measured by Ki-67 labeling index) of tumors and pathological diagnosis. METHODS Localized proton spectra were obtained before stereotactic/surgical biopsy in 7 patients with glioma (8 lesions). Metabolic values in the spectra were measured semiquantitatively and correlated with the Ki-67 labeling index and pathological grade of each surgical specimen. RESULTS MR spectroscopy-guided biopsy was effective in obtaining a representative specimen for accurate pathological diagnosis in all patients, including 1 patient with multifocal glioma and 2 with diffusely infiltrated gliomas (gliomatosis cerebri). Those lesions with higher choline complex/creatine ratio (Cho/Cr) and lower N-acetyl-L-aspartate/creatine values in MR spectroscopy were higher grade tumors. Higher Ki-67 labeling index (indicating higher proliferative activity of tumor) with higher Cho/Cr ratios in MR spectroscopy were significantly correlated with tumor grade. CONCLUSIONS MR spectroscopy-guided biopsy was effective in obtaining a representative specimen for accurate pathological diagnosis, and the Cho/Cr ratio of MR spectra and Ki-67 labeling index were reliable predictors of glioma grade.
Genotyping of Giardia lamblia Isolates from Humans in China and Korea Using Ribosomal DNA Sequences

Genetic characterization of a total of 15 Giardia lamblia isolates, 8 from Anhui Province, China (all from purified cysts) and 7 from Seoul, Korea (2 from axenic cultures and 5 from purified cysts), was performed by polymerase chain reaction amplification and sequencing of a 295-bp region near the 5′ end of the small subunit ribosomal DNA (eukaryotic 16S rDNA). Phylogenetic analyses were subsequently conducted using sequence data obtained in this study, as well as sequences published from other Giardia isolates. The maximum parsimony method revealed that G. lamblia isolates from humans in China and Korea are divided into 2 major lineages, assemblages A and B. All 7 Korean isolates were grouped into assemblage A, whereas 4 Chinese isolates were grouped into assemblage A and 4 into assemblage B. Two Giardia microti isolates and 2 dog-derived Giardia isolates also grouped into assemblage B, whereas Giardia ardeae and Giardia muris were unique.
Effect of Educational Nursing program on reducing the incidence of Venous Thromboembolism among postpartum women.

Background: Venous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and pulmonary embolism (PE), is a serious cause of direct maternal morbidity and mortality in hospitals, that is highly preventable. Literatures strongly support patient education on VTE prevention as it can promote strategies such as early ambulation and encourages self assessment and self reporting of VTE signs and symptoms. Aim of this study was to assess the effect of educational nursing program on reducing the incidence of VTE among postpartum women at Assiut Women’s Health Hospital, postpartum unit and followed up at post partum outpatient clinic. Subjects and Methods: A randomized controlled trial study design used and 400 immediate post partum women were divided randomly into two main groups, intervention and control groups. Intervention group received an educational nursing program about VTE, while the control group received the routine post partum hospital care. Results: Number of new cases of post partum VTE that occurred among women who received the educational program about VTE prevention were significantly lower than those who received the routine hospital post partum care. Women’s knowledge about VTE were significantly improved after implementing the educational program. Conclusions: Findings of this study proved that postpartum women could benefit from the educational nursing program about VTE and this appeared in the occurrence of only one DVT case of the intervention group VS two DVT cases and one pulmonary embolism case among the control group. Recommendations: This study highlights the need to strengthen the nurses’ role in providing patient education about VTE and indicates the need to improve resources that support obstetric nurses in educating their post partum women about VTE.
Banking the Unbanked in Ghana

Financial inclusion is considered an emerging priority for many economies across the globe today because of its potential to speed up economic growth. Banking the unbanked in Ghana is a research endeavour seeking to provide wider access to financial products and services to the estimated 70 percent unbanked population in the country. For the purpose of this study, the research combined both qualitative and quantitative methodologies. The mixed-methods approach was used in order to present a descriptive account and an in-depth investigation of the factors accounting for people’s decision to bank. Data was collected by the use of questionnaires administered to unbanked participants as well as face-to-face interviews with selected individuals. The findings of the study revealed that social factors and firm factors both had significant and positive effects in predicting an individual’s intention to bank. On the contrary, however, personal factors were not found to be significant in predicting banking propensity. The study proposed three key strategic recommendations.