Miracle-dz/UniFAR-FTUs huggingface dataset:
Bioaccumulation of metals by the southern mouthbrooder, Pseudocrenilabrus philander (Weber, 1897) from a mine-polluted impoundment

The bioaccumulation of Fe, Mn, Zn, Cu, Ni and Pb by the cichlid Pseudocrenilabrus philander from a mine-polluted impoundment in the Transvaal was investigated. With the exception of Fe, all the other metals were accumulated in higher concentrations in the tissues of the fish than those in the sediments of the lake, with the highest bioconcentration factor being 8.54 for Zn. Results also showed that there was an inverse relationship between metal concentration and body mass of the fish, with the smaller juvenile fish being better able to concentrate all the metals per equivalent body mass than was the case for the larger, adult fish. This phenomenon is linked to a superior bioregulation mechanism for metals by the larger older fish, as well as the relatively higher metabolic rate of the younger juvenile fish
Formulation and in vitro Evaluation of Piroxicam Emulgel

The present work is concerned with the formulation and evaluation of Piroxicam emulgel employing carbopol 934 and xanthan gum as polymers. The emulgel is prepared by combining the gel and emulsion. The gel in formulations were prepared by dispersing Carbopol 934 and xanthan gum separately in purified water with constant stirring at a moderate speed and then the pH was adjusted to 4 to 5.4 using Tri-ethanol amine (TEA). The oil phase in the emulsion consists of oleic acid and span-80. The aqueous phase in the emulsion was prepared using Tween-80, propylene glycol and distilled water. The prepared emulgel formulations were subjected to evaluation studies like Physical appearance, rheological studies, estimation of drug content and in-vitro drug release. The appearance of prepared emulgel was white. The pH of the emulgel was found to be 5.4. The in vitro drug release studies revealed that formulation F1 showed 85.20% and formulation F2 showed 79.23% of drug release at the end of 8 hrs. The drug release of F1 formulation follows zero order kinetics.
Yarış Atlarında Halothan ve Sevofluran Anestezisinin Kardiyopulmoner Etkilerinin Karşılaştırılması

Bu calismada; yaris atlarinda halothan ve sevofluranin kardiyopulmoner etkileri karsilastirilarak degerlendirildi. Yaslari 4-8 agirliklari 430±47 olan minor ortopedik cerrahi ve kastrasyon uygulanmis toplam 24 yaris ati calismanin materyalini olusturdu. Halothan 14, sevofluran ise 10 ata uygulandi. Butun atlar acepromazin ve xylazin hidroklorid ile premedike edildi. Indiksiyon ketamin hidroklorid ile saglandi. Halothan grubunda inhalasyon anestezisi 8 L/dak O2 ve %5 halothan ile baslandi daha sonra %6 ya, refleksler azaldiginda %3-4 e kadar dusuruldu. Sevofluran grubunda 8 L/dak O2 ve %8 sevofluran konsantrasyonu ile baslandi derin anestezide %3-4 e kadar dusuruldu. Nabiz ve arteriyel kan basinci monitorize edildi. Solunun sayisi inspeksiyon ile belirlendi. Alinan heparinize kanlardan pO2, pCO2 ve pH degerleri saptandi. Olcum zamanlari 0. (baseline), 30. , 60. ve 90. dakikalar olarak belirlendi. Her iki grubun anestezi protokollerinde komplikasyon gozlenmedi. Butun olgularda bradikardi ve hipotansiyon saptanmadi. Solunum sayisi her iki grupta da dustu. Ancak sevofluran grubunda keskin dususler gozlendi (p
The Biological Activities of 20 Nature Identical Essential Oil Constituents

Abstract Twenty nature identical essential oil constituents from seven structural groups were tested for antimalarial, antimicrobial, antioxidant and toxicity properties. The compounds displayed antimalarial activity (IC50 values ranging from 0.9 to 1528.8 μM) with varying toxicity (IC50 values ranging from 5.5 to 1358.4 μM). The data indicates that (-)-pulegone, (E-& Z-)-(±)-nerolidol, linalyl acetate and (+)-α-pinene have the most potent antimalaial activity. Carvacrol (MIC values ranging from <1.66 to 13.3 mM) followed by geraniol (MIC values: 19.5-51.9 mM) displayed the broadest spectrum of antimicrobial activity. The least toxic of the tested compounds, eugenol, was the only compound with antioxidant activity comparable to ascorbic acid. The results demonstrate that the 20 compounds individually display variable biological activity, although further research is required to determine how they may interact when combined.
Investigating ion dyshomeostasis in Niemann-Pick diseasetype C, both in vitro and in vivo

This thesis investigated ion dyshomeostasis within Niemann-Pick disease type C (NPC), a neurodegenerative lysosomal storage disease. Chapter 3 characterizes newly discovered lysosomal Zn2+ storage in NPC, and identifies a novel function for the NPC1 protein as a lysosomal Zn2+ transporter. Zn2+ accumulation appears responsible for some lipid storage within NPC, and treating cells with the Zn2+ chelator phytic acid corrects downstream NPC phenotypes. Chapter 4 investigates Ca2+-modulating therapies for treating NPC. These include tanganil, demonstrated in a recent case study to ameliorate ataxia within NPC patients, and which works by increasing cytosolic Ca2+ to overcome the NPC lysosomal Ca2+ signaling defect. The importance of this Ca2+ signaling defect in NPC can be seen both in the aforementioned beneficial effects of Ca2+ modulating therapies and when looking at NPC-like lipid storage and reduced neuronal Ca2+ spikes observed following treatment of zebrafish with an inhibitor of lysosomal Ca2+ signaling, Ned-19 (Chapter 5). In addition, Chapter 5 describes the generation and characterization of NPC zebrafish treated with inhibitors of npc1 (U18666A, 1NMP) and microinjected with npc1-morpholino. These models accurately recapitulate human NPC phenotypes (characteristic lipid storage, behavioural defects) and can be used to test emerging NPC therapies in vivo (e.g. phytic acid, tanganil). Finally, Chapter 6 explores how different formulations of curcumin, which correct NPC phenotypes both in vitro and in vivo via Ca2+ modulation, have reduced effect and can exacerbate storage in cells when combined with lipid vectors. Having described studies into both Ca2+ and Zn2+ dyshomeostasis in NPC, a new 2-armed pathogenic cascade was hypothesized whereby early dyshomeostasis of lysosomal Ca2+ and Zn2+ generates all downstream NPC phenotypes. Combination therapies with Ca2+ modulators (e.g. tanganil) and Zn2+ chelators (e.g. phytic acid) may provide the best option to treat this complex disease, and require testing both in vitro and in vivo.
An Investigation of the Industrial Ecology of Business Start-up Survival

HENRY RENSKI: An Investigation of the Industrial Ecology of Business Start-up Survival (Under the Direction of Edward Feser) This study examines the influence of external economies on the survival and longevity of new independent businesses in the continental U.S. It hypothesizes that new firms with access to the sources of specialized inputs, labor, product markets and knowledge spillovers will outlive those in areas of relative isolation. The size of the region and the diversity of its industrial base are also considered as possible sources of beneficial external economies. The findings show that while external economies have a statistically significant influence on new firm survival, the effects are typically very modest. The most consistently significant effects are found for localization, which lowers the risk of new firm failure in five of the nine detailed study industries examined: farm and garden machinery, metalworking machinery, motor vehicle parts, advertising and computer and data programming services. After controlling for other sources of external economies, the size of the region is insignificant for most industries. By contrast, regional industrial diversity reduces hazard rates for new firms in drugs, advertising, computer and data processing, and research and testing services. Measures representing the specific sources of localization are statistically significant in fewer industries than the broadly defined measures of localization, but when significant they often have a stronger influence on new firm longevity. Among the specific sources of
Synthesis of an Anticorrosive Pigment by Thermal Treatment of Iron Oxides from Steel Industry Wastes

This work reports the obtaining of an anticorrosive pigment composed mainly of hematite (ɑ-Fe2O3) from a powder steel industry waste from rust scale of rebar steel. This residue is mainly composed of Fe2O3 (87.97 %), SiO2 (6.13 %), CaO (1.88 %), Al2O3 (1.30%) and MnO (0.77 %). The total iron oxide of the residue is constituted by the following crystalline phases: magnetite, maghemita, lepidocrocita, wüstite, goethite and hematite. The production of a pigment with a high content of hematite was possible thanks to the high content of precursor iron oxides, which were calcined at different temperatures (750-850 °C) and holding times (0.5-1.50 h). For characterizing the iron content chemically and to identify their iron oxides phases, it was used X-ray fluorescence (XRF) and X-ray diffraction (XRD). The results showed that the pigment with the highest amount of hematite (ɑ-Fe2O3) was obtained at a calcination temperature of 850 °C and a holding time of 1.00 h.
Adaptive Event Location Technique via Time Difference of Event Arrival

This paper presents the phasor measurement unit (PMU) based event localization technique. In order to achieve the event localization in real-time manner, the proposed method is based on the measurement of the time required of the event propagation at each PMU. When an event propagates through the transmission network, there exists a time delay to arrive electrical buses in wide-area condition. As an initiated time of the event is unknown information in the practical power systems, time difference of arrival (TDoA) is used to estimate the event location instead of time of arrival. In this regard, the key point of the proposed localization utilizes the comparison of TDoA features that are composed of entire transmission lines to estimate the propagation path. As a result, the directions and time difference values in the shortest path are developed as features under the assumption of event location. Furthermore, a historical event-based network training method is proposed to substitute the system state estimation and calculation of propagation speed. Finally, the comparisons between calculated and measured TDoA features could estimate the event bus, and real-world test shows successful estimation results.
Multiobjective optimization of modular structures: Weight versus geometric versatility in a Truss‐Z system

This paper proposes an approach for multicriterial optimization of modular structures with respect to their structural and geometrical properties. The approach is tested using the quickly deployable and reconfigurable modular ramp system Truss‐Z intended for pedestrian traffic. The focus is on modular structures composed of a moderate number of relatively complex modules, which feature an irregular, noncuboidal geometry. Such modules can be assembled into a variety of geometrically different configurations which do not adhere to any predefined spatial grid; their global geometry can be treated as free‐form and determined in situ during construction. The optimization variables represent local‐level geometrical and structural properties of a single module. The Pareto front is used to balance between two kinds of objectives. The geometrical objective quantifies the ability of the modules to generate geometrically versatile global structures that are well‐suited to comply with spatial constraints of real construction sites. The structural objective is formalized in analogy to the minimum weight problem with upper bound constraints imposed on the von Mises stress and the Euler buckling load ratio. A two‐level optimization scheme is employed with NSGA‐II at the top level and a simulated annealing with adaptive neighborhood at the lower level.
High-Order Harmonic Resonances in Traction Power Supplies: A Review Based on Railway Operational Data, Measurements, and Experience

Harmonic resonances in traction power supply systems (TPSSs) have attracted great attention due to their potentially destructive impact on the safe and stable operation of railways. Based on operation data acquired from Chinese railways, this paper presents a comprehensive review of this issue considering both academic and engineering requirements. Analyzing actual incidents, the general patterns and effects of TPSS resonances are derived. The relation between the TPSS and the locomotive is illustrated by circuit models. Relevant methods for modeling locomotives and TPSSs are discussed. Both advanced resonance analysis methods giving general influence factors and a simplified resonance analysis explaining resonance features in a practical manner are discussed. Multiple ground-based and on-board solutions for resonance elimination are presented. At last, preidentifying resonances in actual systems is investigated for addressing the open topic of resonance prevention.
EUV-Induced Plasma: A Peculiar Phenomenon of a Modern Lithographic Technology

After a long period of relatively low interest, science related to effects in the Extreme Ultraviolet (EUV) spectrum range experienced an explosive boom of publications in the last decades. A new application of EUV in lithography was the reason for such a growth. Naturally, an intensive development in such area produces a snowball effect of relatively uncharted phenomena. EUV-induced plasma is one of those. While being produced in the volume of a rarefied gas, it has a direct impact onto optical surfaces and construction materials of lithography machines, and thus has not only scientific peculiarity, but it is also of major interest for the technological application. The current article provides an overview of the existing knowledge regarding EUV-induced plasma characteristics. It describes common, as well as distinguishing, features of it in comparison with other plasmas and discusses its interaction with solid materials. This article will also identify the gaps in the existing knowledge and it will propose ways to bridge them.
Design and Evaluation of a Control Scheme for the Hybrid Cascaded Converter in Grid Applications

Compared with the well-known modular multilevel cascaded converter with single-star bridge-cells (MMCC-SSBC), the hybrid cascaded converter (HCC) has the advantage of the lower component count of power transistors and dc capacitors. Thereby, this paper explores the HCC in grid applications and proposes a hierarchical control scheme, which allows the HCC to operate under unbalanced grid conditions and power imbalances among all cells. The HCC is further compared with the MMCC-SSBC under these unbalanced conditions to evaluate its performance. The laboratory test results are provided to verify the proposed control scheme and the comparison. The operational flexibility and reliability of the HCC are also discussed.
Measuring Project’S Team Culture in Projects Using the Last Planner System

At this stage, construction industry is known for bad project performances and a culture characterized by adversarial behaviours. The Last Planner  System (LPS) is designed to improve these circumstances through the enhancement of workflow reliability by involving various disciplines in joint planning processes and a culture of collaboration. How to actually measure related project team culture (PTC) is unknown at this stage. This paper tries to close this gap and compares two defined versions of the Ideal Lean Culture for organizations with the actual PTC in projects using the LPS. It first presents the two Ideal Lean Cultures for organizations, based on a framework developed for organizations (the Competing Values Framework - CVF). Next, it examines on the basis of three case studies the applicability of the CVF for measuring the actual culture in project teams using the LPS and compares it with the named Ideal Lean Culture conditions. The paper concludes that the CVF is a suitable tool to take a snapshot of the PTC and that the comparison to the Ideal Lean Culture can give conclusions about the current project team’s maturity in projects using the LPS.
Gold Catalysis: Fundamentals and Recent Developments

We present an overview of fundamental organometallic transformations in relation to gold chemistry. The focus of this chapter is to provide comprehensive depth of oxidative addition, transmetalation, reductive elimination, β-hydride elimination, and migratory insertion reactions for the benefit of gold catalysis. Recent advances of these reactions enables intelligent catalyst design and pushes the frontier of homogenous gold catalysis.
Statistical Study on Space Charge effects and Stage Characteristics of Needle-Plate Corona Discharge under DC Voltage

The air’s partial discharges (PD) under DC voltage are obviously affected by space charges. Discharge pulse parameters have statistical regularity, which can be applied to analyze the space charge effects and discharge characteristics during the discharge process. Paper studies air corona discharge under DC voltage with needle-plate model. Statistical rules of repetition rate (n), amplitude (V) and interval time (∆t) are extracted, and corresponding space charge effects and electric field distributions in PD process are analyzed. The discharge stages of corona discharge under DC voltage are divided. Furthermore, reflected space charge effects, electric field distributions and discharge characteristics of each stages are summarized to better explain the stage discharge mechanism. This research verifies that microcosmic process of PD under DC voltage can be described based on statistical method. It contributes to the microcosmic illustration of gas PD with space charges.
Integrating components of sustainability into chemical engineering curricula

Sustainability has been gaining attention worldwide due to rising evidences of environmental problems and societal issues.Tertiary education has responded to the attention by taking a series of initiatives for delivering knowledge of sustainability.Among all, engineering discipline appears to be among the most active in seeking to integrate the components ofsustainable development into its curricula. Many researchers have studied the approaches used for integratingsustainability knowledge into engineering education, but most of these studies are only relevant to the European,American and Australian contexts. The relevant information in the Asian context is scant, due to limited published reportsor literature on how the Asian universities, including Malaysian’s, are integrating sustainability into their engineeringcurricula. Therefore, this study aims at studying the current approach used by the Malaysian universities to integratesustainability into its engineering curricula and identifying which approach is more effective for such integration. Thisstudy targeted at the chemical engineering undergraduate programme in five selected universities in Malaysia. A surveywas used and a total of 173 responses were collected. Correlation analysis was then conducted. It was found that theundergraduates’ knowledge and interest level of sustainable development was unsatisfactory. The results revealed thatspecific and compulsory courses related to sustainable development could be more effective for delivering knowledge ofsustainability for the undergraduates, a finding that was different from that suggested in the existing literature for theWestern Countries such as the United States, United Kingdom, the Netherlands, Sweden and others.
A Case for Reproducibility in MIR: Replication of 'A Highly Robust Audio Fingerprinting System'

Claims made in many Music Information Retrieval (MIR) publications are hard to verify due to the fact that (i) often only a textual description is made available and code remains unpublished – leaving many implementation issues uncovered; (ii) copyrights on music limit the sharing of datasets; and (iii) incentives to put effort into reproducible research – publishing and documenting code and specifics on data – is lacking. In this article the problems around reproducibility are illustrated by replicating an MIR work. The system and evaluation described in ‘A Highly Robust Audio Fingerprinting System’ is replicated as closely as possible. The replication is done with several goals in mind: to describe difficulties in replicating the work and subsequently reflect on guidelines around reproducible research. Added contributions are the verification of the reported work, a publicly available implementation and an evaluation method that is reproducible.
Developments in knowledge discovery processes and methodologies: anything new?

The process of turning data into knowledge is referred to as “knowledge discovery” (KD) and originated in the 1990s. Since that time many different process models and methodologies have been developed. A genealogy presented in 2010, showed how the different models evolved and presented a refined process model, which represents a synthesis of the models presented before. However, the rise of data analytics and big data have changed how organizations do business. The key to these changes is to use data and turn it into knowledge to create value for the organization. Therefore, this study aims to update our understanding of knowledge discovery processes by reviewing the research into KD processes since 2010 in order to understand if there have been considerable changes and developments in this field. The developments in KD process models and methodologies that were found are threefold: tasks, steps and agile practices.
Topology and Control of a Four-Level ANPC Inverter

Four-level hybrid-clamped inverter is a newly proposed topology that can operate under a wide voltage range without switches connected in series. However, when it is applied in medium voltage high power conversions, the flying capacitors in each phase will occupy a huge volume and a high switching frequency is required to restrain the voltage ripples. In order to overcome this drawback, a four-level active neutral-point clamped inverter is discussed in this paper, which consists of only six switches and no diodes or flying capacitors are required. In order to balance the neutral-point voltages under the full power factor and modulation index range, a capacitor voltage balance method based on carrier-overlapped pulsewidth modulation is proposed in this paper. The upper and lower dc-link capacitor voltages are balanced by zero-sequence voltage injection and the central dc-link capacitor voltage is balanced by adjusting the duty cycles of switching signals slightly. Simulation and experimental results are presented to confirm the validity of this method.
HOW TO TEACH WRITING IN LITERATURE CLASS THROUGH GENRE-BASED APPROACH

This present study was conducted in order to portray how to teach writing in literature class throgh Genre-Based Approach. Specifically, this study identifies (1) how lecturer guides students write their response to literature through Genre-Based Approach, and (2) how the students write their response to literature using Genre- Based Approach. Qualitative case study design was chosen as the method of the study. The participants were 1 lecturer and 40 students who studied Prose in English Education Study Program at one state university in Palembang. The data were collected through observation, documentation, and questionnaire. The data were analyzed qualitatively by doing thematic analysis. The result shows that (1) all the procedures of Genre-Based Approach which incorporated Building Knowledge of The Field (BKOF), Modelling, Joint Construction and Independent writing were helpful in facilitating students writing, specifically BKOF and Joint Construction; (2) Most of the participants, to some extents, have applied the schematic structures (introduction, expands-on and summary) and the linguistic features modeled in this study.