Miracle-dz/UniFAR-FTUs huggingface dataset:
A conceptual e-service quality model for career sites

the increasing number of publications in e-recruiting and e-service quality, little research has been conducted on factors determining e-service quality for career sites in specific. In this paper, models for determining website quality and thus factors influencing e-service quality as well as determinants for successful (e-)recruitment have been investigated by conducting two systematic literature researches in the fields of e-service quality and (e-)recruitment. The dimensions found were compared and where possible combined to ensure determining factors which applied to career sites specifically. The resulting model contains seven dimensions: 1) quality of information, 2) security/trust, design of a website regarding 3) appearance and 4) useability), 5) enjoyment/entertainment, 6) system quality and 7) customer service.
Attention guidance for immersive video content in head-mounted displays

Immersive videos allow users to freely explore 4 π steradian scenes within head-mounted displays (HMD), leading to a strong feeling of immersion. However users may miss important elements of the narrative if not facing them. Hence, we propose four visual effects to guide the user's attention. After an informal pilot study, two of the most efficient effects were evaluated through a user study. Results show that our approach has potential but it remains challenging to implicitly drive the user's attention outside of the field of view.
Measles Virus Interacts with and Alters Signal Transduction in T-Cell Lipid Rafts

ABSTRACT By a contact-dependent surface interaction, the measles virus (MV) glycoprotein complex induces a pronounced inhibition of T-cell proliferation. We now show that MV directly interacts with glycosphingolipid-enriched membrane microdomains on human primary T cells and alters recruitment and segregation of membrane proximal signaling components. Contact-dependent interference with T-cell receptor-stimulated tyrosine phosphorylation and Ca mobilization is a late event seen 24 h after MV treatment. In contrast, stimulated recruitment of pleckstrin homology domain-containing proteins such as Akt and Vav is inhibited early after MV contact, as is segregation of the activated Akt kinase from rafts. Tyrosine phosphorylation of the regulatory subunit of the phosphatidylinositol 3-kinase (PI3K), p85, is apparently normal then, yet this protein fails to partition to the lipid raft fraction, and this is associated with stable expression of its negative regulator Cbl-b. Thus, by interaction with lipid rafts, MV contact initially targets recruitment of PI3K by preventing stimulated Cbl-b degradation and activation of PI3K-dependent signaling components.
4-Methylumbelliferyl-β-N-Acetylglucosaminide Hydrolysis by a High-Affinity Enzyme, a Putative Marker of Protozoan Bacterivory

Hydrolysis of an artificial fluorogenic substrate, 4-methylumbelliferyl-β-N-acetylglucosaminide, has been studied in a monoculture predator-prey system with either a flagellate (Bodo saltans) or a ciliate (Cyclidium sp.) fed upon pure bacterial culture (Aeromonas hydrophila or Alcaligenes xylosoxidans). Aeromonas hydrophila produced a low-affinity β-N-acetylglucosaminidase-like enzyme (Km, ≫100 μmol liter-1) but Alcaligenes xylosoxidans did not. Inoculation of both bacterial strains with bacterivorous protozoa induced the occurrence of another, high-affinity, β-N-acetylglucosaminidase-like enzyme (Km, <0.5 μmol liter-1). The latter enzyme showed significant, close correlations with total grazing rates of both B. saltans (r2 = 0.96) and Cyclidium sp. (r2 = 0.89) estimated by using uptake of fluorescently labelled bacteria. Further significant correlations between several protozoan parameters and kinetic parameters of this enzyme suggest its likely protozoan origin. If both types of enzyme occurred together, they could be satisfactorily distinguished by using kinetic data analysis. Hence, measurements of β-N-acetylglucosaminidase-like activities might be promising to use to improve estimations of protozoan bacterivory.
Pathologic Responses of Lambs to Experimental Inoculation with Acholeplasma Laidlawii

16. Rock DL, Hagemoser WA, Osorio FA, McAllister HA: 1988, with deletions in the latency and early protein O genes: repliTranscription from the pseudorabies virus genome during latent cation, virulence and immunity in neonatal piglets. J Vet Diagn infection. Arch Virol 98:99-106. Invest O:OOO–OOO. 17. Southern EM: 1975, Detection of specific sequences among 19. Zhu X, Chen J, Young CHS, Silverstein S: 1990, Reactivation DNA fragments separated by gel electrophoresis. J Mol Biol 98: of latent herpes simplex virus by adenovirus recombinants en503-518. coding mutant IE-O gene products. J Virol 64:4489-4498. 18. Wesley RD, Cheung AK: 1995, A pseudorabies virus mutant
On possibilities for action: The past, present and future of affordance research

We give a historical overview of the development of almost 50 years of empirical re- search on the affordances in the past and in the present. Defined by James Jerome Gibson in the early development of the Ecological Approach to Perception and Action as the prime of perception and action, affordances have become a rich topic of investi- gation in the fields of human movement science and experimental psychology. The methodological origins of the empirical research performed on affordances can be traced back to the mid 1980's and the works of Warren (1984, 1988) and Michaels (1988). Most of the research in Ecological Psychology performed since has focused on the actualization of discretely defined actions, the perception of action boundaries, the calculation of pi-numbers, and the measurement of response times. The research ef- forts have resulted in advancements in the understanding of the dynamic nature of affordances, affordances in a social context and the importance of calibration for per- ception of affordances. Although affordances are seen as an instrumental part of the control of action most studies investigating affordances do not pay attention to the control of the action. We conclude that affordances are still primarily treated as a util- ity to select behaviour, which creates a conceptual barrier that hinders deeper un- derstanding of affordances. A focus on action-boundaries has largely prevented ad- vancement in other aspects of affordances, most notably an integrative understanding of the role of affordances in the control of action.
Computerized tomographic morphometric analysis of subaxial cervical spine pedicles in young asymptomatic volunteers.

BACKGROUND Although cervical spine pedicle screws have been shown to provide excellent fixation, widespread acceptance of their use is limited because of the risk of injury to the spinal cord, nerve roots, and vertebral arteries. The risks of pedicle screw insertion in the cervical spine can be mitigated by a three-dimensional appreciation of pedicle anatomy. Normative data on three-dimensional subaxial pedicle geometry from a large, young, and asymptomatic North American population are lacking. The purpose of the present study was to determine three-dimensional subaxial pedicle geometry in a large group of young volunteers and to determine level and sex-specific morphologic differences. METHODS Helical computerized tomography scans were made from the third cervical to the seventh cervical vertebra in ninety-eight volunteers (sixty-three men and thirty-five women) with an average age of twenty-five years. Pedicle width, height, length, and transverse and sagittal angulations were measured bilaterally. Pedicle screw insertion positions were quantified in terms of mediolateral and superoinferior offsets relative to readily identifiable landmarks. RESULTS The mean pedicle width and height at all subaxial levels were sufficient to accommodate 3.5-mm screws in 98% of the volunteers. Pedicle width and height dimensions of <4.0 mm were rare (observed in association with only 1.7% of the pedicles), with 82% occurring in women and 72% occurring unilaterally. Screw insertion positions generally moved medially and superiorly at caudal levels. Transverse angulation was approximately 45 degrees at the third to fifth cervical levels and was less at more caudal levels. Sagittal angulation changed from a cranial orientation at superior levels to a caudal orientation at inferior levels. Mediolateral and superoinferior insertion positions and sagittal angulations were significantly dependent (p < 0.05) on sex and spinal level. Transverse angulation was significantly dependent (p < 0.05) on spinal level. CONCLUSIONS Pedicle screw insertion points and orientation are significantly different (p < 0.05) at most subaxial cervical levels and between men and women. Preoperative imaging studies should be carefully templated for pedicle size in all patients on a level-specific basis. Although the prevalence was low, women were more likely to have pedicle width and height dimensions of <4.0 mm.
Los factores competitivos de la empresa a partir de la perspectiva de los distritos industriales. Un estudio de industria de cerámica de revestimiento brasileña

Esta tesis ha tenido como objetivo general estudiar los factores competitivos de la empresa, a partir de la perspectiva de los distritos industriales, centrandose en el caso de la industria de ceramica de revestimiento brasilena. Se ha tomado un trabajo de referencia que se ha realizado en Espana y se ha incorporado los resultados de Brasil, en terminos de la existencia de unos recursos compartidos, o sea, aquellos propios de las localizaciones donde la industria brasilena de ceramica de revestimiento estuviese concentrada. El primer capitulo se presenta la perspectiva teoricas relevantes para la comprension de la ventaja competitiva de las empresas que estan relacionadas con el desarrollo de los distritos industriales - la perspectiva de recursos, capacidades dinamicas y del conocimiento y de los costes de transacion. En el capitulo segundo se ha descrito las formas organizativas colectivas - las redes de empresas - con enfasis en los distritos industriales. Partiendo de los dos capitulos anteriores, se ha planteado los objetivos o preguntas especificas de la investigacion y la manera de alcanzarla. En el capitulo cuarto se presenta una descripcion del objeto de estudio, centrandose en las dos aglomeraciones territoriales que se ha estudiado - Criciuma y Santa Gertrudis - destacando su evolucion a lo largo del tiempo, sus particularidades y estado actual. En el capitulo se explica la metodologia que se ha aplicado, resaltando el aspecto cualitativo y cuantitativo del estudio, ademas de los procedimientos de recogida y tratamiento de los datos. En el capitulo seis, se presentan los resultados, contestando a las preguntas planteadas a la investigacion. El capitulo siete presenta las siguientes conclusiones: En Brasil hay dos distritos industriales del tipo abierto. Ellos son distintos entre si tanto en terminos de posesion de factores competitivos, como de resultados empresariales. Los distritos de
Microsurgical Removal of Olfactory Groove Meningiomas via the Pterional Approach

Commonly used frontobasal approaches for microsurgical removal of olfactory groove meningiomas have certain disadvantages, such as late exposure of the neurovascular complex located dorsal to the tumor, namely, the internal carotid artery, middle cerebral artery, anterior cerebral artery, and the optic nerves. In addition, the frontal sinuses are frequently opened and there can be compression of the frontal lobes from significant spatula pressure. We report our experience with the pterional approach for these tumors in 28 patients. All patients presented with hyposmia/anosmia; 20 had personality changes and 8 had visual deficits. At surgery, after dissection of the sylvian fissure, the internal carotid artery, middle cerebral artery, anterior cerebral artery, and the homolateral optic nerve were exposed before removal of the posterior tumor parts. Reduction of focal pressure was achieved by removal of the contralateral tumor following partial resection of the falx and crista galli. Total tumor removal was obtained in all but 1 patient. One patient died of pulmonary embolism. The psychoorganic syndrome resolved in all but 1 patient; visual deficits improved in 6 patients. There were no postoperative infections. We consider the pterional approach to be superior to others for these lesions because it provides early exposure of the neurovascular complex, preservation of the frontal venous drainage, and avoidance of postoperative cerebrospinal fluid fistulae.
Efficacy of garcinia cambogia on body weight, inflammation and glucose tolerance in high fat fed male wistar rats.

INTRODUCTION Obesity leads to derangements in lipid and glucose homeostasis resulting in various metabolic complications. Plants containing vital phytochemicals are known to posses anti obesity properties and have proved to exert beneficial effects in obesity. OBJECTIVES The present study was aimed to investigate the effects of Garcinia Cambogia on body weight, glucose tolerance and inflammation in high fat diet fed male Wistar rats. MATERIALS AND METHODS Five month old male wistar rats (n=40) were divided into four groups. Two groups were fed with standard rodent diet and the remaining two with 30% high fat diet. One group in each of the two sets received the crude ethanolic extract of Garcinia Cambogia at a dose of 400mg/kg body weight/day for ten weeks. Body weight, intraperitoneal glucose tolerance test, leptin, tumour necrosis factor-α (TNF-α) and renal function (urea, creatinine, uric acid) were studied. RESULTS High fat diet fed rats showed increased body weight gain, glucose intolerance, elevated levels of plasma leptin and TNF-α. Supplementation of Garcinia Cambogia extract (GE) along with high fat diet significantly decreased body weight gain, glucose intolerance, plasma leptin and TNF-α level. No significant changes were observed in the renal function parameters in any of the groups. CONCLUSION Supplementation of the Garcinia Cambogia extract with high fat diet reduced body weight gain, inflammation and glucose intolerance.
The clinical investigator as an endangered species.

THIS paper deals with the physician-investigator as an endangered species and with the future of clinical research. Clinical research includes the wide range of activities extending from epidemiology to studies of patients, to laboratory studies of specimens and tissues. Clinical research is usually conducted by physician-investigators working in a clinical department of a medical school or in a clinical division of an institute. An increasing number of Ph.D.'s are also engaging in clinical research, but this paper will be largely devoted to the physician-investigator. For several years there has been a declining interest in biomedical research on the part of .
Endotoxin reduces specific pulmonary uptake of radiolabeled monoclonal antibody to angiotensin-converting enzyme.

The biodistribution of radiolabeled monoclonal antibody (Mab) to angiotensin-converting enzyme (ACE) was examined in normal and endotoxin-treated rats. Endotoxin administration at a dose of 4 mg/kg induced mild or middle pulmonary edema. The ACE activity in lung homogenate remained virtually unchanged, while the activity of serum ACE increased 15 hr after endotoxin infusion. In normal rats, anti-ACE Mab accumulates specifically in the lung after i.v. injection. Endotoxin injection induces reduction of specific pulmonary uptake of this antibody. Even in non-edematous endotoxemia, the accumulation of anti-ACE Mab antibody (Mab 9B9) decreased from 19.02 to 11.91% of ID/g of tissue without any change in accumulation of control nonspecific IgG. The antibody distribution in other organs and its blood level were almost the same as in the control. In a case of endotoxemia accompanied by increased microvascular permeability, the lung accumulation of Mab 9B9 was reduced to 9.17% of ID/g of tissue, while the accumulation of nonspecific IgG increased to 1.44% versus 0.89% in the control.
Molecular detection and characterization of piroplasms infecting cervids and chamois in Northern Spain

Wildlife can act as reservoir of different tick-borne pathogens of veterinary and zoonotic importance. To investigate the role of wild ruminants as reservoir of piroplasm infection, 28 red deer, 69 roe deer and 38 chamois from Northern Spain were examined by reverse line blot (RLB) hybridization. The survey detected a prevalence of 85·7% in red deer, 62·3% in roe deer and 28·9% in chamois. Four different piroplasms were identified: Theileria sp. OT3 (previously described in sheep) as the most prevalent (85·7% in red deer, 46·4% in roe deer and 26·3% in chamois); Theileria sp. 3185/02 (previously described in a red deer in Central Spain) more abundant in red deer (53·6%) than in roe deer (10·1%) but absent from chamois; Babesia divergens detected in 6 roe deer; Theileria ovis present in 1 chamois. Mixed infections (Theileria sp. OT3 and Theileria sp. 3185/02) were only found in red and roe deer. Sequencing analysis of the 18S rRNA gene confirmed the RLB results and showed 99·7% identity between Theileria sp. 3185/02 and T. capreoli, suggesting that they are the same species. Tick distribution and contact of wild ruminants with domestic animals are discussed in terms of piroplasm infection. The results suggest that a considerable number of wildlife ruminants are asymptomatic carriers that may serve as reservoirs of the infection posing a serious concern in terms of piroplasmosis control.
Silicate Esters of Paclitaxel and Docetaxel: Synthesis, Hydrophobicity, Hydrolytic Stability, Cytotoxicity, and Prodrug Potential

We report here the synthesis and selected properties of various silicate ester derivatives (tetraalkoxysilanes) of the taxanes paclitaxel (PTX) and docetaxel (DTX) [i.e., PTX-OSi(OR)3 and DTX-OSi(OR)3]. Both the hydrophobicity and hydrolytic lability of these silicates can be (independently) controlled by choice of the alkyl group (R). The synthesis, structural characterization, hydrolytic reactivity, and in vitro cytotoxicity against the MDA-MB-231 breast cancer cell line of most of these derivatives are described. We envision that the greater hydrophobicity of these silicates (vis-à-vis PTX or DTX itself) should be advantageous from the perspective of preparation of stable aqueous dispersions of amphiphilic block-copolymer-based nanoparticle formulations.
Breastfeeding Knowledge, Attitude, and Practice and Related Determinants Among Maternal in Gondar, Ethiopia: Cross-Sectional Study

Breastfeeding has always been the ideal feeding practice for infants because of that it is one of the components of Primary Health Care and considered as natural practices in Ethiopia even though it remains a challenging due to lack of knowledge of mothers. The objective of this study was to assess the breastfeeding knowledge, attitude, practice and related Determinants among Maternal in Gondar; Northwest Ethiopia. A cross sectional community based study was carried out from September to December, 2015 in Gondar City. A total of 543 women who had a child aged less than 24 months from five different villages. The sample size determination was calculated using the single proportion formula. Households that have lactating mothers who had child less than 24 months were selected by multistage random sampling technique. The questionnaire was distributed according to the proportion of the selected village population Data were analyzed using SPSS v21. Binary logistic regressions were used to see the strength of association between independent and dependent variables using odds ratios and 95% of confidence intervals. Finally a multivariate logistic regression analysis was made to identify the predictors of maternal knowledge about optimal breastfeeding practices. Full breastfeeding was reported by 59.3%, mixed feeding was reported by 31.3% and infant formula feeding was reported by 12.4%. Almost one third of the full breastfeeding group did so for 7–12 months, and almost two thirds did continue breastfeeding for more than one year. Employed women were more likely not to practice full breastfeeding compared to unemployed women (odds ratio 3.34, 96% CI 1.60, 6.98), and women who had caesarian delivery were more likely not to repetition full breastfeeding compared to those who had vaginal delivery (odds ratio 2.36, 97% CI 1.17, 4.78). The women had a positive attitude but short maternity leaves had a negative impact on breastfeeding. This study showed that a majority of mothers has known the importance of Exclusive Breast Feeding and have good attitude, knowledge in order that strongly agree that Exclusive Breast Feeding is advantageous for infant aged less than six months. Though, poor practice to exclusive breastfeeding for the first six months postpartum among urban mothers. It is speculated health care providers and decision makers should be comprehensively addressed on adverse work related issues to improve exclusively breast feeding practices in the study community.
Re-Inquiries Television ’ s Cultivation of Material Values

Prior research has shown that television viewing cultivates perceptions of the prevalence of societal affluence through a memory-based process that relies on the application of judgmental heuristics. This article extends this research by examining (1) whether cultivation effects generalize to consumer values such as materialism and (2) whether these values judgments are also processed in a heuristic manner. Data from both a survey and an experiment suggest that television cultivates materialism through an online process in which television’s influence is enhanced by active (rather than heuristic) processing during viewing. This finding stands in contrast to the cultivation of prevalence judgments, which are attenuated by active processing during judgment elicitation.
Higher multiple births in Switzerland: neonatal outcome and evolution over the last 20 years.

QUESTION UNDER STUDY The study has following objectives: 1) to determine the incidence of higher-order multiple births from 2005 to 2008 in Switzerland and its evolution over the last twenty years, and 2) to analyse the neonatal outcome and its change over the last two decades. METHODS Data on higher-order multiple births were retrospectively obtained from Swiss obstetric and neonatal hospitals and compared with results from the first two national surveys. RESULTS The incidence of higher-order multiple births was 35.3/100,000 live births for triplets, 0.7/100,000 for quadruplets and 0.3/100,000 for quintuplets. All newborns were premature with a median gestational age of 32 1/7 weeks for triplets, 29 2/7 weeks for quadruplets and 28 4/7 weeks for quintuplets. 94% of triplets and all quadruplets and quintuplets survived the neonatal period. Over the last two decades, the incidence of quadruplet and quintuplet births has fallen, while that of triplet births has risen by 40%. The perinatal mortality of triplets has decreased and the neonatal morbidity, mainly respiratory distress, has remained constant. CONCLUSION Higher-order multiple births have a high morbidity that has not improved over the last two decades. The incidence of higher-order multiple births is still increasing, which demonstrates that reproductive medicine in Switzerland is not yet sufficiently controlled and monitored.