Miracle-dz/UniFAR-FTUs huggingface dataset:
Management of Peroneal Nerve Paralysis in a Three Month old Puppy using a Tendon Transplantation Technique J. O. Omamegbe and A. V. Okorie 8-14 Small Ruminant Lungworms: Parasite detection, identification and prevalence estimation in Three Districts of South Wollo, Ethiopia

The main objective of this paper was to compare growth traits and heterosis of body parameters of two varieties of Archachatina marginata (var. ovum and var. saturalis) and their crosses under experimental conditions. Three hundred (300) juvenile snails (Archachatina marginata), one hundred (100) each of A. marginata var. ovum, A. marginata var. saturalis and their crosses with mean body weights of 12.40 ± 0.58 g were used for the study. The snails were randomly allotted using completely randomized design into three (3) treatment varieties. Results from the study showed significant variety effect (P<0.05) on final body weight and average weight gain. The crossbred variety recorded the highest average weight gain compared to the other two varieties. No significant (P>0.05) variety effect was observed on daily weight gain, total feed intake, daily feed intake and feed conversion ratio. The crossbred variety recorded the highest final body weight and final shell width, indicating heterotic effects on these two bodies and shell parameters. Significant variety effects (P<0.05) were observed on body weight, shell length and shell “mouth” length. The low heterotic values obtained for body weight and the shell parameters supported the assertion that growth traits have low heterotic values which may be due to their high heritability. Though, low and positive heterotic values were obtained for all parameters studied, the crossbred variety recorded the highest heterotic values, which indicated that it may have heterotic advantage over the purebred varieties.
Immunomodulatory Effect of Dietary Turmeric against Aflatoxins in Mice: Histological and Immunohistochemical Study

The Journal is an Egyptain journal covering the whole field of general, experimental, systematic and applied entomology. Manuscripts generally should not exceed 30 pages (exceptions are possible, particularly in case of reviews, and should be negotiated in advance with the editors). Papers are considered by referees before acceptance. Authors will receive first editorial decision within 8 weeks from confirmed submission. All contributions are published in English. Authors whose mother tongue is not English are strongly urged to have their manuscripts reviewed linguistically before submission. Papers written in poor English will be returned. It is understood that manuscripts submitted to EAJBS have not been offered to any other journal for prior or simultaneous publication. www.eajbs. eg.net Provided for non-commercial research and education use. Not for reproduction, distribution or commercial use.
Work-family balance measures in companies and employees’ work satisfaction: the effect of work-family enrichment

This paper analyses the relationship between a group of different practices of work-fam-ily balance and the employees’ job satisfaction, as well as the relationship between job satisfaction and employee’s organizational commitment. We differentiate this relationship according to the level of work-family (W-F) enrichment and family-work (F-W) enrichment, as well as we analyze the role of work-family (W-F) and family-work (F-W) conflict. We use a sample of 322 employees, and test the relationships with structural equations. The results show that a higher use of work-family practices has more beneficial effects on enrichment and conflict, and that both enrichment and conflict influence employees’ job satisfaction. However, higher levels of interference or stress at work make employees feel less satisfied at work. The paper highlights the positive role of enrichment in order to improve employee’s job satisfaction as well as to increase his/her organizational commitment.
Caenorhabditis elegans model for admixed proteinopathy of Huntington’s and Alzheimer-type

Formation of proteinaceous deposits composed of abnormally aggregated proteins characterizes a range of pathological conditions. Proteinaceous inclusions detected in the neurodegenerative conditions such Huntington’s chorea (HD) and Alzheimer’s disease (AD) are often referred as pathognomic and regarded as causally implicated. Despite of differences in aetiology and underlying genetics, rare cases of combined HD and AD were reported and described as admixed proteinopathies. Mixed proteopathies are characterized by the co-occurrence of at least two types of abnormal aggregation-prone variants; pathological deposition of proteinaceous inclusions might however, affect different cell populations. Here, combining plaques derived from human ß-amyloid with mutant HTT-like polyglutamine inclusions in a cell-autonomous manner, we report on the Caenorhabditis elegans model for admixed proteinopathy of Alzheimer’s and Huntington’s type. We show both types of intracellular foci are formed in vivo: non-amyloidic extended polyglutamine derived inclusions and distinguish those from the presence of mature ß- amyloid fibers. We found that polyglutamines expanded above pathogenic threshold and ß-amyloid act synergistically to promote the progression of proteotoxicity in a temperature dependent manner. We further, implicate the hsp-1 (the predominant C. elegans chaperone interacting with ER-routed Aß42) modulate the proteotoxic insults observed in combined proteopathy model. Our results demonstrate how the in vivo model of admixed proteopathy could be utilized to probe for human pathogenic variants confined to the same cellular type. In that perspective expanded aggregation-prone polyglutamines appended with fluorescent proteins could be regarded as ‘pathogenic probes’ useful in the proteotoxicity assays i.e. involving ß-amyloid and possibly other comparable models of disease-associated aggregation prone variants.We anticipate models of combined proteopathies will be informative regarding the underlying pathogenesis and provide the sensitized background for sophisticated screening. For example the combinatorial effects of multiple pathogenic aggregation-prone variants could be tested against mutant backgrounds and pharmacological compounds. Furthermore, we surmise the postulated synergistic actions might explain some of the overlaps in observed progression of clinical symptoms in HD and AD. We also formulate the conjecture regarding the polyQ containing proteins as a contributing factor in degenerative conditions associated with increased ß-amyloid formation and deposition.
Longevity Risk Management: Models and Hedging Strategies

Longevity risk management is becoming increasingly important in the pension and life insurance industries. The unexpected mortality improvements observed in recent decades are posing serious concerns to the financial stability of defined-benefit pension plans and annuity portfolios. It has recently been argued that the overwhelming longevity risk exposures borne by the pension and life insurance industries may be transferred to capital markets through standardized longevity derivatives that are linked to broad-based mortality indexes. To achieve the transfer of risk, two technical issues need to be addressed first: (1) how to model the dynamics of mortality indexes, and (2) how to optimize a longevity hedge using standardized longevity derivatives. The objective of this thesis is to develop sensible solutions to these two questions. In the first part of this thesis, we focus on incorporating stochastic volatility in mortality modeling, introducing the notion of longevity Greeks, and analysing the properties of longevity Greeks and their applications in index-based longevity hedging. In more detail, we derive three important longevity Greeks—delta, gamma and vega—on the basis of an extended version of the Lee-Carter model that incorporates stochastic volatility. We also study the properties of each longevity Greek, and estimate the levels of effectiveness that different longevity Greek hedges can possibly achieve. The results reveal several interesting facts. For example, we found and explained that, other things being equal, the magnitude of the longevity gamma of a q-forward increases with its reference age. As with what have been developed for equity options, these properties allow us to know more about standardized longevity derivatives as a risk mitigation tool. We also found that, in a delta-vega hedge formed by q-forwards, the choice of reference ages does not materially affect hedge effectiveness, but the choice of times-to-maturity does. These facts may aid insurers to better formulate their hedge portfolios, and issuers of mortality-linked securities to determine what security structures are more likely to attract liquidity. We then move onto delta hedging the trend and cohort components of longevity risk under the M7-M5 model. In a recent project commissioned by the Institute and Faculty of Actuaries and the Life and Longevity Markets Association, a two-population mortality model called the M7-M5 model is developed and recommended as an industry standard
Exploring levels of egg parasitism and variation in egg cuticular chemistry in different Clavigralla spp.

Clavigralla spp. (Hemiptera: Coreidae) are major pests of cowpea (Vigna unguiculata (L.) Walp, Fabacae), common bean (Phaseolus vulgaris L., Fabacae) and pigeon pea (Cajanus cajan L., Fabacae) in Africa. Clavigralla spp. egg parasitoids, Gryon spp. (Hymenoptera: Scelionidae), have previously been reported as potential biological control candidates. Little is known about the parasitism levels and their potential relationship with cuticular chemistry of Clavigralla spp. The aims of this study were to determine parasitism levels of Clavigralla tomentosicollis Stål (Hemiptera: Coreidae) and C. elongata Signoret (Hemiptera: Coreidae) eggs, and to explore the relationship between egg parasitism and egg cuticular chemistry. High parasitism levels were determined for C. tomentosicollis by collecting eggs from plants in mono‐cropping and multi‐cropping systems in farmers’ fields in Bénin and Kenya between April and June 2016. Three species of Clavigralla were recorded: C. tomentosicollis, C. shadabi and C. elongata. Clavigralla tomentosicollis was the most common in both countries, while C. shadabi and C. elongata were only collected in Bénin and Kenya, respectively. An egg parasitoid (Gryon sp.) was recovered from egg batches collected from both countries. In parasitism assays using Gryon sp. , the incidence of parasitism was higher in C. tomentosicollis eggs than that of C. elongata. Chemical analysis by coupled gas chromatography/mass spectrometry (GC/MS) of cuticular extracts obtained from C. tomentosicollis and C. elongata eggs identified fifteen compounds including ten alkanes of which the amounts varied between the two species. We speculate that Clavigralla spp. cuticular chemistry may serve as potential host location cues for Gryon sp.
Absorption, Translocation, and Toxicity of Glyphosate and Oxyfluorfen in Yellow Nutsedge (Cyperus esculentus)

The potential for yellow nutsedge (Cyperus esculentus L. var. leptostachyus Boeck. # CYPES) regrowth was reduced by increasing plant age and by glyphosate [N-(phosphonomethyl)glycine] and oxyfluorfen [2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene]. Of the amount of glyphosate transported to underground parts, most was found in the tubers, with immature rhizomes, roots, and tubers having 2 to 3 times higher concentrations than comparable mature tissues. Addition of unlabeled oxyfluorfen as a tank mixture with glyphosate increased absorption and translocation, mainly into leaves and new tubers, of radioactivity from 14C-glyphosate in 30-day-old plants. In contrast to the younger plants, the addition of oxyfluorfen decreased 14C-glyphosate detected in 60-day-old plants. The greater effectiveness of glyphosate when applied with oxyfluorfen on yellow nutsedge at the early growth stage has important implications in the field because the tuberization process must be stopped early in the development of the plant for successful control.
Appropriability: Theorisation essay on the role of appropriation in the second-hand item purchase process

This article presents a theorisation essay on the role of appropriation in the second-hand item purchase process. It highlights the concept of appropriability, which is defined as the relative potential of an object to become a consumer’s complete and entire possession. An item’s appropriability potential is relative to the prevalence of displayed traces from a previous owner or owners and the nature of the motivation that led to its acquisition. It also affects both the phases of a second-hand object’s appropriation process: (1) the Distancing phase, the intensity of which varies according to the prevalence of the Other’s trace and (2) the Absorption phase, the strategies of which – Denial, Creativity and Mastery – are defined by the nature of the purchase motivation.
Concurrent use of ciprofloxacin and metronidazole for controlling of some bacterial infections in broiler chickens

This study was carried out to investigate the efficacy of ciprofloxacin (8 mg/kg b.wt.) and/or metronidazole (30 mg/kg.b.wt.) in drinking water for 5 successive days for treatment of E. coli and/or Cl. perfringens each alone or both. Bloodand tissue samples were collected from 5 birds from each group on the 5th, 12th and 19th days post-infection and treatment.This was done through studying the effect on growth Performance (body weight, weight gain, feed consumption and feedconversion rate), lesion score, mortality rate, some liver and kidney function parameters and some blood pictureparameters. Infection with E. coli and/or Cl. perfringens induced the characteristic symptoms and lesions of the diseaseinfection with E. coli induced mortality rate up to 20% which is reduced to 5% post- treatment with ciprofloxacin whereas,Cl. perfringens infection induced mortality up to 35% which is reduced to 12% post-treatment with metronidazole. Mixedinfection with E. coli and Cl. perfringens induced 75% mortality which is reduced to 20% post-treatment with both drugs.Infection with E. coli and/or Cl. perfringens each alone or mixed together afforded a significant decrease in body weight,weight gain, feed consumption and increased feed conversion compared with normal control group. Whereas, treatmentof infected birds with both drugs elicited a significant increase in body weight, feed consumption and significant decreasein feed conversion rate compared with infected non-treated groups. On blood picture infection with E. coli and Cl.perfringens or their mixed infection induced a significant decrease in total RBCs count, Hb % and PCV% whereas,treatment of infected birds with each drug alone or their combination induced a significant increase in the previousparameters along the course of the study compared with infected non-treated groups. Serum Aspartate aminotransferase(AST), Alanine aminotransferase (ALT), Alkaline phosphatase (ALP), uric acid and creatinine were significantly elevatedin response to infection with each microbe alone or their combination compared with normal control group. Treatment ofinfected birds with each drug alone or their combination elicited a significant decrease in the previous parameters alongentire period of the study compared with the infected non-treated groups. Taken together, our data could be framed withinthe view of the revealing high efficacy of metronidazole and ciprofloxacin toward infection with clostridium and /or E.coli in poultry
Broadening of Cloud Droplet Size Distributions by Condensation in Turbulence

To consider the growth of cloud droplets by condensation in turbulence, the Fokker–Planck equation is derived for the droplet size distribution (droplet spectrum). This is an extension of the statistical theory proposed by Chandrakar and coauthors in 2016 for explaining the broadening of the droplet spectrum obtained from the “Π-chamber”, a laboratory cloud chamber. In this Fokker–Planck equation, the diffusion term represents the broadening effect of the supersaturation fluctuation on the droplet spectrum. The aerosol (curvature and solute) effects are introduced into the Fokker–Planck equation as the zero flux boundary condition at R = 0, where R is the droplet radius, which is mathematically equivalent to the case of Brownian motion in the presence of a wall. The analytical expression for the droplet spectrum in the steady state is obtained and shown to be proportional to R exp (-cR), where c is a constant. We conduct direct numerical simulations of cloud droplets in turbulence and show that the results agree closely with the theoretical predictions and, when the computational domain is large enough to be comparable to the Π-chamber, agree with the results from the Π-chamber as well. We also show that the diffusion coefficient in the Fokker–Planck equation should be expressed in terms of the Lagrangian autocorrelation time of the supersaturation fluctuation in turbulent flow.
Robust multivariate nonparametric tests via projection averaging

In this work, we generalize the Cram\'er-von Mises statistic via projection-averaging to obtain a robust test for the multivariate two-sample problem. The proposed test is consistent against all fixed alternatives, robust to heavy-tailed data and minimax rate optimal against a certain class of alternatives. Our test statistic is completely free of tuning parameters and is computationally efficient even in high dimensions. When the dimension tends to infinity, the proposed test is shown to have comparable power to the existing high-dimensional mean tests under certain location models. As a by-product of our approach, we introduce a new metric called the angular distance which can be thought of as a robust alternative to the Euclidean distance. Using the angular distance, we connect the proposed method to the reproducing kernel Hilbert space approach. In addition to the Cram\'er-von Mises statistic, we demonstrate that the projection-averaging technique can be used to define robust, multivariate tests in many other problems.
Pengaruh Kompetensi terhadap Kinerja Perangkat Nagari dalam Pengelolaan Keuangan Nagari di Kabupaten Tanah Datar

This study aimed to determine the influence of competence on performance of nagari government apparatus in managing nagari finance in Tanah Datar regency. This study was conducted with quantitative approach. The population of this study was all nagari government apparatus in Tanah Datar regency as many as 525 people consisting of nagari secretary, nagari treasurer, and five head of nagari affairs. The sample in this study consisted of 227 respondents determined with Slovin formula and Multi Stage Random Sampling technique. The data of this study were collected through questionnaire with likert scale measurement. Data of this study were analyzed with multiple linear regression test. The finding of this study indicated that the influence of knowledge sub-variables on the performance of nagari government apparatus in nagari financial management was 5.6%; the influence of skill on the financial management was equal to 7,3%; and the influence of attitude sub variable on the nagari financial management was equal to 8,5%. At the same time, the influence of knowledge, skills, and attitudes on the performance of financial management was 10.3%. Thus it could be concluded that the competence of nagari government apparatus consisting of knowledge, skills, and attitudes significantly influenced their performance in nagari financial management.
Driving Brand Engagement Through Online Social Influencers: An Empirical Investigation of Sponsored Blogging Campaigns

Influencer marketing is prevalent in firm strategies, yet little is known about the factors that drive success of online brand engagement at different stages of the consumer purchase funnel. The findings suggest that sponsored blogging affects online engagement (e.g., posting comments, liking a brand) differently depending on blogger characteristics and blog post content, which are further moderated by social media platform type and campaign advertising intent. When a sponsored post occurs on a blog, high blogger expertise is more effective when the advertising intent is to raise awareness versus increase trial. However, source expertise fails to drive engagement when the sponsored post occurs on Facebook. When a sponsored post occurs on Facebook, posts high in hedonic content are more effective when the advertising intent is to increase trial versus raise awareness. The effectiveness of campaign incentives depends on the platform type, such that they can increase (decrease) engagement on blogs (Facebook). The empirical evidence for these findings comes from real in-market customer response data and is supplemented with data from an experiment. Taken together, the findings highlight the critical interplay of platform type, campaign intent, source, campaign incentives, and content factors in driving engagement.
Peroxisome Proliferator Activated Receptor Gamma Sensitizes Non-small Cell Lung Carcinoma to Gamma Irradiation Induced Apoptosis

The nuclear receptors known as peroxisome proliferator activated receptor gamma (PPARG) are lipid-activated transcription factors that have emerged as key regulators of inflammation. PPARG ligands have been shown to have an anti-proliferative effect on a variety of cancers. These ligands can induce apoptosis via TP53 (Tumor protein p53) or ERK1/2 (Extracellular signal-regulated kinases 1/2) (EPHB2) pathways. However, the exact mechanism is not known. PPAR, a type II nuclear hormone receptor deserves attention as a selective target for radiotherapy. Our study examines the potential of selective agonism of PPARG for radiation therapy in non-small cell lung carcinoma (NSCLC). We found that the overexpression of PPARG protein as well as its induction using the agonist, rosiglitazone was able to stimulate radiation-induced cell death in otherwise radio resistant NSCLC A549 cell line. This cell death was apoptotic and was found to be BAX (BCL2 associated X) mediated. The treatment also inhibited radiation-induced AKT (Protein Kinase B) phosphorylation. Interestingly, the ionising radiation (IR) induced apoptosis was found to be inversely related to TP53 levels. A relatively significant increase in the levels of radiation induced apoptosis was observed in H1299 cells (TP53 null) under PPARG overexpression condition further supporting the inverse relationship between apoptosis and TP53 levels. The combination of PPARG agonist and radiation was able to induce apoptosis at a radiation dose at which A549 and H1299 are radioresistant, thus confirming the potential of the combinatorial strategy. Taken together, PPARG agonism was found to invigorate the radiosensitising effect and hence its use in combination with radiotherapy is expected to enhance sensitivity in otherwise resistant cancer types.