Miracle-dz/UniFAR-FTUs huggingface dataset:
Systematic Review of Tendon Transfer Versus Nerve Transfer for the Restoration of Wrist Extension in Isolated Traumatic Radial Nerve Palsy

Purpose: To compare the outcomes of tendon transfer and nerve transfer for radial nerve palsy. Methods: We performed a systematic review of the literature in EMBASE, PubMed, and Cochrane Database to include studies that address persistent traumatic radial nerve palsy treated with tendon transfer or nerve transfer surgery. Results: We identified 2,044 citations; 1,512 texts were excluded because of content, and 96 texts were screened for eligibility. Texts were excluded if they did not report the motor score (M0 to M5 as determined by the British Medical Research Council) or measurements of range of motion of the wrist. Sixteen texts were eligible for qualitative synthesis. Outcomes of these studies show heterogeneity with regard to the technique and functional restoration. Conclusions: On the basis of the results of this systematic review, there does not seem to be a clearly superior technique; rather, there are advantages and disadvantages to each. Patient selection and surgeon experience are important when considering surgical interventions in this challenging clinical scenario. Nerve transfer surgery is an emerging technique that may offer patients meaningful functional gains with reduced donor site morbidity. Level of Evidence: Level III
CaSK23, a Putative GSK3/SHAGGY-Like Kinase of Capsicum annuum, Acts as a Negative Regulator of Pepper’s Response to Ralstonia solanacearum Attack

GSK3-like kinases have been mainly implicated in the brassinosteroids (BR) pathway and, therefore, in plant growth, development, and responses to abiotic stresses; however, their roles in plant immunity remain poorly understood. Herein, we present evidence that CaSK23, a putative GSK3/SHAGGY-like kinase in pepper, acts as a negative regulator in pepper’s response to Ralstonia solanacearum (R. solanacearum) inoculation (RSI). Data from quantitative RT-PCR (qRT-PCR) showed that the constitutively-expressed CaSK23 in pepper leaves was down-regulated by RSI, as well as by exogenously-applied salicylic acid (SA) or methyl jasomonate (MeJA). Silencing of CaSK23 by virus-induced gene silencing (VIGS) decreased the susceptibility of pepper plants to RSI, coupled with up-regulation of the tested genes encoding SA-, JA-, and ethylene (ET)-dependent pathogenesis-related (PR) proteins. In contrast, ectopic overexpression (OE) of CaSK23 conferred a compromised resistance of tobacco plants to RSI, accompanied by down-regulation of the tested immunity-associated SA-, JA-, and ET-dependent PR genes. In addition, transient overexpression of CaSK23 in pepper plants consistently led to down-regulation of the tested SA-, JA-, and ET-dependent PR genes. We speculate that CaSK23 acts as a negative regulator in pepper immunity and its constitutive expression represses pepper immunity in the absence of pathogens. On the other hand, its decreased expression derepresses immunity when pepper plants are attacked by pathogens.
Bidisperse Magnetic Particles Coated with Gelatin and Graphite Oxide: Magnetorheology, Dispersion Stability, and the Nanoparticle-Enhancing Effect

The magnetorheology and dispersion stability of bidisperse magnetic particles (BMP)-based magnetorheological (MR) fluids were improved by applying a novel functional coating composed of gelatin and graphite oxide (GO) to the surfaces of the micron-sized carbonyl iron (CI) and nanoparticles Fe3O4. Gelatin acted as a grafting agent to reduce the aggregation and sedimentation of CI particles and prevent nanoparticles Fe3O4 from oxidation. In addition, a dense GO network on the surface of gelatin-coated BMP was synthesized by self-assembly to possess a better MR performance and redispersibility. The rheological properties of MR fluids containing dual-coated BMP were measured by a rotational rheometer under the presence of magnetic field and their dispersion stability was examined through sedimentation tests. The results showed that CI@Fe3O4@Gelatin@GO (CI@Fe3O4@G@GO) particles possessed enhanced MR properties and dispersion stability. In addition, the nanoparticle-enhancing effects on the dispersion stability of BMP-based MR fluids were investigated using Monte Carlo simulations.
Childhood Maltreatment, Attachment, and Borderline Personality–Related Symptoms: Gender-Specific Structural Equation Models

Objectives: Survivors of early interpersonal trauma may experience relational problems, anger, impulsive and self-destructive behaviors, identity disturbance, and other difficulties that are associated with borderline personality disorder. Insecure attachment also has been documented in survivors and may be related to borderline personality–related symptoms (BPRS). The goal of the current study was to examine an integrative model of maternal and paternal childhood maltreatment and insecure attachment as they predict BPRS. Method: The sample was composed of 954 participants who completed self-report measures of parental maltreatment during childhood, attachment security, and trauma-related symptoms. Results: Structural equation modeling suggested differential impacts of maternal and paternal maltreatment on male and female participants. Both maternal and paternal maltreatment were directly associated with BPRS in women, whereas in men, only paternal maltreatment was directly related to BPRS. In women, paternal maltreatment was indirectly associated with BPRS through attachment anxiety but not through attachment avoidance. In men, maternal maltreatment was indirectly associated with BPRS through attachment anxiety but not through attachment avoidance. Conclusion: These findings have implications for the understanding of gender-specific etiologies of borderline personality symptoms and underscore attachment security as an important intervention target.
Surgical therapy and next-generation sequencing-based genetic alteration analysis of malignant solitary fibrous tumor of the pleura

Background Solitary fibrous tumor of the pleura (SFTP) is a rare pleural neoplasm arising from mesenchymal cells, accounting for <5% of pleural neoplasms. Approximately 10% of cases of SFTP demonstrate malignant potential, leading to local recurrence after radical surgery and subsequent metastasis. Methods A large malignant-like mass was found in the left thoracic cavity of a 61-year-old woman. Following radical resection of the mass, the patient was diagnosed with malignant SFTP by histologic and immunohistochemical analyses. In addition, a next-generation sequencing-based mutation test was used to reveal the mutational profile of the tumor. The genetic alteration panel was analyzed with reference to public data on the ClinVar and COSMIC databases, after which the public SFTP data were analyzed for frequency of altered genes. Finally, through overlay of the abovementioned two sets, the genetic alteration accounting for SFTP initiation was anticipated to be identified. Results In the mutation panel of our malignant SFTP group, kinase insert domain receptor (KDR) and fms-related tyrosine kinase 1 (FLT1) scored high in pathogenesis but had only a medium frequency; the NAB2–STAT6 fusion appeared to be the dominant genetic alteration in public SFTP samples. Conclusion The high frequency of NAB2–STAT6 fusion indicates its prominent role in SFTP, while somatic mutations such as FLT1-R593W and KDR-V297I may also contribute to the malignant angiogenic phenotype. The present study affirmed the heterogeneity of SFTP, and more sophisticated classification methods will be needed to explore its underlying mechanisms. Summary We believe that improvement in the prognosis of SFTP relies on early diagnosis, margin-free resection, and long-term follow-up. Through genetic analysis, it appears that both NAB2–STAT6 fusion and somatic mutations such as FLT1-R593W and KDR-V297I contribute to SFTP development.
Focusing of Terahertz Radiation With Laser-Ablated Antireflective Structures

Numerical simulations and experimental characterization of laser-ablated focusing antireflective and phase-shifting structures for terahertz frequencies are presented. More than 10% shift of reflectance minimum to lower frequencies was predicted by simulations for relatively coarse structures with the period of 100 $\mu$m in comparison with that of a substantially smaller period and with results of the model used for the design of antireflective surfaces in the terahertz range. Such a shift of the resonance frequency can be employed to optimize the thickness of antireflective layers simultaneously obtaining additional means of more precise control of layer properties due to ablation of larger structures. Nearly 90% transmittance of silicon wafers within 0.5–0.6 THz frequencies was confirmed experimentally. Optical path differences equivalent to a half period at 0.53 THz, suitable for applications in high-efficiency zone plates, were demonstrated with high transmittance simultaneously. Possibilities of delay adjustment up to one wavelength were illustrated by numerical simulations. A focusing binary zone plate for 0.6 THz was produced employing phase-shift differences of the dual-function antireflective layer. Its close to diffraction-limited focusing performance was evaluated, further confirming sufficient uniformity of the structured layer.
Satellite Image Classification with Deep Learning

Satellite imagery is important for many applications including disaster response, law enforcement, and environmental monitoring. These applications require the manual identification of objects and facilities in the imagery. Because the geographic expanses to be covered are great and the analysts available to conduct the searches are few, automation is required. Yet traditional object detection and classification algorithms are too inaccurate and unreliable to solve the problem. Deep learning is a family of machine learning algorithms that have shown promise for the automation of such tasks. It has achieved success in image understanding by means of convolutional neural networks. In this paper we apply them to the problem of object and facility recognition in high-resolution, multi-spectral satellite imagery. We describe a deep learning system for classifying objects and facilities from the IARPA Functional Map of the World (fMoW) dataset into 63 different classes. The system consists of an ensemble of convolutional neural networks and additional neural networks that integrate satellite metadata with image features. It is implemented in Python using the Keras and TensorFlow deep learning libraries and runs on a Linux server with an NVIDIA Titan X graphics card. At the time of writing the system is in 2nd place in the fMoW TopCoder competition. Its total accuracy is 83%, the F1score is 0.797, and it classifies 15 of the classes with accuracies of 95% or better.
Energy and Reliability Improvement of Voltage-Based, Clustered, Coarse-Grain Reconfigurable Architectures by Employing Quality-Aware Mapping

An energy–quality scalable coarse grain reconfigurable architecture (CGRA) based on the voltage overscaling (VOS) technique is presented. The approximation level of each processing element (PE) in the CGRA is determined by the applied VOS-determined voltage level. By employing the technique, the architecture may be configured for accurate or approximate modes of computation depending on a user-specified output quality-of-service target for a given application. More precisely, operating voltages used for performing various operations in the application dataflow graph are minimized subject to the output quality constraint by using an energy–quality tradeoff algorithm. To make the hardware implementation of the scheme more efficient, PEs are clustered into groups of (e.g., <inline-formula> <tex-math notation="LaTeX">$3\times 1$ </tex-math></inline-formula> and <inline-formula> <tex-math notation="LaTeX">$2\times 1$ </tex-math></inline-formula>) voltage islands. To assess the efficacy of the proposed method in improving the power (energy) consumption and reliability of CGRAs, different combinations of minimum output quality constraints, voltage levels, and cluster sizes for several benchmarks are studied. Simulation results indicate considerable reductions in energy consumption (up to 43%) and aging rate (up to 73%) when compared with the conventional CGRA with perfect output quality (i.e., with no approximate computations).
PTSD and Comorbid Depression: Social Support and Self-Efficacy in World Trade Center Tower Survivors 14–15 Years After 9/11

Objective: Following the World Trade Center (WTC) terrorist attack in New York City, prevalence rates of posttraumatic stress disorder (PTSD) and depression remain elevated. Although social support and self-efficacy have been associated with PTSD, little is known about their differential effect on PTSD and depressive comorbidity. Method: WTC tower survivors (n = 1,304) were assessed at Wave 1 (2003–2004), Wave 2 (2006–2007), Wave 3 (2011–2012), and Wave 4 (2015–2016). Results: At Wave 4, 13.0% of participants had probable PTSD, a decrease from 16.5% at Wave 1. In addition, 4.1% (54) were identified as having PTSD alone, 6.8% (89) had depression alone, and 8.9% (116) had comorbid PTSD and depression. Of those with PTSD, 68.2% also had comorbid depression. WTC tower survivors with PTSD and comorbid depression reported greater PTSD symptom severity and were more likely to have had greater exposure to the events of 9/11 (adjusted odds ratio [aOR] = 1.14) and lower self-efficacy (aOR = 0.85) than those with depression alone. Less perceived social support predicted only depression and not PTSD, whereas less perceived self-efficacy equally predicted having PTSD or depression (aOR = 0.76). Conclusions: Findings indicate that self-efficacy may be more important to the severity and chronicity of PTSD symptoms than social support. Multivariate comparisons suggest that PTSD with comorbid depression is a presentation of trauma-dependent psychopathologies, as opposed to depression alone following trauma, which was independent of trauma exposure and may be secondary to the traumatic event and posttraumatic response. Implications for assessment and treatment are discussed.
Collaborative Remembering of Emotional Autobiographical Memories: Implications for Emotion Regulation and Collective Memory

People frequently engage in conversation about shared autobiographical events from their lives, particularly those with emotional significance. The pervasiveness of this practice raises the question whether shared memory reconstruction has the power to influence the memory and emotions associated with such events. We developed a novel paradigm that combined the strengths of the methods from autobiographical and collaborative memory research traditions to examine such consequences. We selected a shared, real-life autobiographical event of an exam, and asked students to recall their memory of taking a recent exam where they provided a group and/or personal narrative of this autobiographical event. Students first recalled the event either collaboratively (C) or individually (I), followed by a final individual (I) recall by all. Valence ratings as well as the emotional tone of the narratives converged to show that prior collaborative remembering down-regulated negative emotion and enhanced the positive emotional tone of the memories. The recalled detail in the narratives indicated that at initial recall members of collaborative groups reported fewer internal details than those who recalled alone, and reported more external details in a later recall when working alone. Earlier collaboration also increased collective memory such that more of these details were shared among prior group members in their later individual recall compared with those who did not collaborate before. We discuss the influence of collaborative remembering on shaping memory and emotion for autobiographical events as well as the potential mechanisms that promote collective autobiographical memory.
The mouthparts of female Corethrella brakeleyi and C. wirthi (Diptera: Chaoboridae)

The mouthparts of female Corethrella brakeleyi and C. wirthi were studied using light and electron microscopy. Mandibles, hypopharynx and labium are highly sclerotized and are modified for obtaining blood meals. All structures were larger in C. brakeleyi than in C. wirthi except mandibular and hypopharyngeal teeth; these were smaller and more numerous in C. brakeleyi. The labium of both species terminates in peg‐like structures which are similar to those reported from several genera of mosquitoes. Sensillae on the second segment of the maxillary palps appear to be identical to those described in both biting and nonbiting male and female blackflies.
Clinical Value of Combining 18F-FDG PET/CT and Routine Serum Tumor Markers in The Early Detection of Recurrence Among Follow-up Patients Treated for Cervical Squamous Cell Carcinoma

Objective: The purpose of this retrospective study was to investigate the role of 18F-Fluorodeoxyglucose Positron Emission Tomography (18F-FDG PET/CT) and evaluate if combined elevated serum tumor markers levels improve the accuracy of 18F-FDG PET/CT in detecting recurrence of cervical squamous cell carcinoma. Methods: A total number of 42 patients who were treated for cervical squamous cell carcinoma and had underwent 18F-FDG PET/CT for suspected recurrence of cervical cancer were retrospectively reviewed in this study and their clinical, pathological and serological data were collected and analyzed. The clinical value of combining 18F-FDG PET/CT with serum tumor markers was investigated. Results: Among the 42 patients, 18F-FDG PET/CT was true positive in 25 (59.5%), false positive in 5 (11.9%), true negative in 12 (28.5%) and false negative in none. The overall patient-based sensitivity, specificity, accuracy, positive predictive value and negative predictive value of 18F-FDG PET/CT in detecting recurrent cervical cancer were 100%, 70.6, 88.1%, 83.3%, and 100%, respectively. The accuracy of 18F-FDG PET/CT with combined squamous cell carcinoma antigen (SCC Ag) and carcinoembryonic antigen (CEA) elevation was 100% compared to only SCC Ag elevation and only CEA elevation, 90% and 33.3%, respectively. The positive predictive value of a positive 18F-FDG PET/CT with combined SCC Ag and CEA elevation was 100% for detection of recurrent cervical cancer. Also, the negative predictive value of a negative 18F-FDG PET/CT combined with normal SCC Ag and CEA levels was 100%. Conclusion: 18F-FDG PET/CT is highly sensitive in the diagnosis of recurrent cervical cancer. When 18F-FDG PET/CT is associated with both SCC Ag and CEA elevation or only SCC Ag elevation, the accuracy is increased but not when associated with only CEA elevation. Positive 18F-FDG PET/CT associated with both tumor markers elevation can precisely predict recurrence. Moreover, normal levels of both tumor markers with a negative 18F-FDG PET/CT result may clinically reassure that a recurrence is absent.
Measurement matters: higher waist-to-hip ratio but not body mass index is associated with deficits in executive functions and episodic memory

Background The current study aimed to reconcile the inconsistent findings between obesity, executive functions, and episodic memory by addressing major limitations of previous studies, including overreliance on body mass index (BMI), small sample sizes, and failure to control for confounds. Methods Participants consisted of 3,712 midlife adults from the Cognitive Project of the National Survey of Midlife Development. Executive functions and episodic memory were measured by a battery of cognitive function tests. Results We found that higher waist-to-hip ratio was associated with deficits in both executive functions and episodic memory, above and beyond the influence of demographics, comorbid health issues, health behaviors, personality traits, and self-perceived obesity. However, higher BMI was not associated with deficits in executive functions and episodic memory. More importantly, these differential associations were robust and stable across adulthood. Discussion Our findings confirm the association between obesity and episodic memory while highlighting the need for better measures of obesity when examining its associations with individual differences in cognitive functions.
Association of MiRNA122 & ADAM17 with Lipids among Hypertensives in Nigeria

Abstract Background Dyslipidaemia and hypertension are established major risk factors for cardiovascular diseases. The suggested roles of miRNA-122 and ADAM17 in lipid metabolism can therefore be applied in the management of metabolic disorders. The authors’ aim was to determine the association between miRNA-122 and ADAM17, as well as the association between miRNA-122 and lipid fractions, in the study participants. Method A comparative cross-sectional study was conducted among 200 hypertensive patients and 100 non-hypertensive adult controls between May, 2015, and June, 2016, in Nigeria. Lipids were analysed with spectrophotometric methods whereas ADAM17 and miRNA-122 were analysed with enzyme linked immunosorbent assay and quantitative polymerase chain reaction, respectively. Results The mean (standard deviation [SD]) ages of 200 hypertensives and 100 controls were 56.3 (6.9) and 54.9 (8.3) years, respectively. miRNA-112 and ADAM17 had significantly higher values among dyslipidaemic individuvals compared with non-dyslipidaemic participants. The correlation between miRNA-122 and ADAM17 levels was strongly positive, r=0.82, p<0.05. LDL-cholesterol and total cholesterol also showed statistically significant positive correlation with miRNA-122, r=0.53, r=0.51, (p< 0.001) respectively. Conclusion In this study, miRNA-122 showed a strong correlation with ADAM17 and a positive correlation with LDL-cholesterol and total cholesterol. These findings support the stimulant roles of miRNA-122 and ADAM17 in lipid metabolism and thus could be used in the management of dyslipidaemia.
The effect of REDV/TiO2 coating coronary stents on in-stent restenosis and re-endothelialization

The coronary artery stent has been widely used in clinic. In-stent restenosis was mainly caused by the excessive proliferation of smooth muscle cell and the inflammation due to the metal ion released from stent scaffold of the drug-eluting stent. Thus, to reduce the in-stent restenosis and promote the vascular endothelialization have become a hot research point in this area. In this paper, a nano-TiO2 ceramic coating was deposited on 316L stainless steel to reduce the metal ion release and to inhibit the inflammation reaction. An endothelia cell selective adhesion peptide Arg-Glu-Asp-Val (REDV) coating was prepared on the ceramic coating by a polydopamine technology to promote the endothelialization. The corrosion test indicated that nano-TiO2 ceramic film could effectively decrease the nickel ion released from 316L stainless steel. REDV/TiO2 coating could promote the endothelial cell adhesion and proliferation, meanwhile REDV/TiO2 coating could also increase the nitric oxide concentration. Bare metal stent, TiO2-coated stent and REDV/TiO2-coated stent were implanted in the iliac arteries of rabbit model. In-stent restenosis and re-endothelialization were evaluated at 28 days post-implantation of the stents. The results showed that REDV/TiO2-coated stents could effectively reduce in-stent restenosis and promote re-endothelialization in comparison with TiO2-coated drug-eluting stent and bare metal stent. These results suggest that REDV/TiO2-coated drug-eluting stent maybe a good choice of the application for coronary artery disease.