Miracle-dz/UniFAR-FTUs huggingface dataset:
PENGARUH VARIABEL EKONOMI DAN NON EKONOMI TERHADAP IMPOR INDONESIA DARI ASEAN+6 MELALUI MODA TRANSPORTASI LAUT

Selama periode tahun 2007-2011 impor Indonesia dari negara-negara ASEAN+6 didominasi oleh impor bahan baku dan bahan penolong. Faktor-faktor yang mempengaruhi dominannya impor Indonesia yang dimaksud, khususnya impor Indonesia yang diangkut melalui moda transportasi laut, merupakan tema utama tulisan ini. Variabel-variabel yang digunakan dalam analisis dengan menggunakan model gravity meliputi variabel ekonomi, yakni GDP per kapita ASEAN+6, GDP per kapita Indonesia, jarak ekonomi, nilai tukar riil, dan variabel non-ekonomi, yakni kualitas pelabuhan, stabilitas politik dan efektivitas pemerintahan Indonesia. Hasil estimasi dengan menggunakan pendekatan gravity model menunjukkan bahwa variabel yang secara signifikan berpengaruh positif pada impor Indonesia adalah GDP per kapita Indonesia dan kualitas pelabuhan Indonesia. Sedangkan variabel jarak ekonomi, nilai tukar riil, stabilitas politik dan efektivitas pemerintahan Indonesia secara signifikan berpengaruhnegatif. During 2007-2011, the Indonesia’s imports from the ASEAN+6 countries were dominated by the raw materials. The factors that influence volumes of the Indonesia’s imports, expecially which transported by sea transport mode, become the main topic of this research. The variables of the gravity model used in this research are economic variables, i.e. per capita GDP of ASEAN+6, Indonesia’s per capita GDP, economic distance, and real exchange rate, as well as non-economic variables such as Indonesia’s quality of sea port, political stability and government effectiveness. Estimation using the gravity model shows that the variables of Indonesia’s per capita GDP and Indonesia’s quality of sea ports significantly have positive influence on Indonesia’s imports, while the variables of economic distance, real exchange rate, political stability and government effectiveness significantly have negative influence.
Two‐dimensional speckle tracking echocardiography of acute cardiac transplant rejection following pregnancy

A 44‐year‐old woman, who had undergone orthotopic cardiac transplantation in 1999, presented acute allograft rejection 4 months after childbirth. Analysis of myocardial deformation by speckle tracking echocardiography showed, in contrast with traditional markers of systolic function, a strong reduction of left ventricular strain, which recovered, together with rejection, under pharmacological treatment. This case documents the potential advantages of speckle tracking echocardiography in the noninvasive management of transplant recipients. © 2012 Wiley Periodicals, Inc. J Clin Ultrasound 40:451–454, 2012
A New 1MHz-2GHz Permeance Meter For Metallic Thin Films

We have developed a permeance meter in the 1 MHz-2 GHz range using a shielded loop type pickup coil. The effect of grounding between drive coil and pickup coil was analyzed using time domain reflectometry (TDR). The grounding increased the output voltage and eliminated the multiple reflections in the drive coil. Using the grounding, magnetic thin film permeance can be measured accurately over a wide frequency range. The complex permeance is shown of a l /spl mu/m thick Co/sub 85/Nb/sub 12/Zr/sub 3/ film.
A non-invasive study to estimate and compare salivary sialic acid level as tumor marker in patients with pre-cancer and oral cancer.

INTRODUCTION Sialic acids are important terminal sugars of the carbohydrate chains of cell membrane glycoproteins and glycolipids. The progressive rise in total sialic acid (TSA) levels has been significantly associated with tumor progression and metastasis. MATERIALS AND METHODS Samples of 2 ml of unstimulated whole saliva were collected from 20 healthy patients, and 20 cases of histopathologically confirmed oral pre-cancer patients and 20 cases of histopathologically confirmed oral squamous cell carcinoma (OSCC) patients, using the method of Navazesh. Estimation of total sialic acid was done by the histochemical method of Yao et al. RESULTS The study revealed significantly elevated total sialic acid (TSA) levels in the saliva of oral precancer and OSCC patients, yielding a mean value of 59.75 ± 7.29 mg/dl and 204.85 ± 60.38 mg/dl, respectively, against the mean value of 21.65 ± 5.71 mg/dl of the healthy controls. Also, high total sialic acid (TSA) levels in the well-differentiated squamous cell carcinoma cases were appreciable to those of moderately differentiated ones. DISCUSSION AND CONCLUSION The result suggests the correlation of elevated salivary TSA levels with the progression of OSCC. In conclusion, the study indicates that the glycoprotein metabolism is significantly altered in the saliva of patients, with both oral pre-cancer and OSCC.
Spillover Effects of Unconventional Monetary Policy in Asia and the Pacific

We assess the evolution of spillover effects of unconventional monetary policies on Asia and the Pacific region, and evaluate the impact on and implications for the macroeconomy. We develop a Panel Vector Auto Regression model for the Asia and Pacific region for a period covering data from first quarter 2000 until first quarter 2015. We split the overall sample into two subsets: the Pre-Crisis (2000q1–2006q4) and Post-Crisis (2009q1–2015q1) samples. We identify unconventional monetary policy shocks with a shadow interest rate estimated by Krippner (2013). We find that Asia and the Pacific region has responded to the advanced economies’ actions with accommodative monetary policy. Such lower interest rates were coupled with currency appreciation, asset price inflation, and strong movements in capital flows. Foreign investors have shifted their preferences for bonds in Asia and the Pacific. If prior to the Global Financial Crisis, the “global saving glut” hypothesis (i.e., Asian savings flight to the US) was one of the major effects resulting in booming US house prices, it is clear that a reversal effect has dominated the economy after the Global Financial Crisis: funds flight to Asia and the Pacific region putting pressure on asset prices, leading to financial vulnerability.
Study of lipoprotein patterns as an atherogenic factor in T2DM patients and their FDRs.

BACKGROUND The present study was carried out to determine the lipoprotein patterns as an atherogenic factor in T2DM (Type 2 Diabetes Mellitus) patients and their FDRS (First Degree Relatives). In various previous studies it has been reported that hyperinsulinemia and hyperlipidemia frequently coexist in T2DM patients which indicate that the diabetic state it self is associated with atherogenic lipid disorders. METHOD The present study included 26 Type 2DM (T2DM) patients and 21 apparently healthy First Degree Relative (FDRs) of T2DM patients. Twenty three age matched control not related to diabetics were also included in the study. RESULTS The BMI in male patients and FDRs were significantly higher as compared to controls but no significant difference was seen among the BMI of female FDRs. Fasting plasma glucose (FPG) levels of T2DM patients were significantly higher but no significant difference was observed among the FDRs and controls. FPG did not show any significant correlation with the BMI in diabetic patients, FDRs and controls. The lipid profile of patients showed no significant difference, except the mean LDL-Chol of female patients was significantly higher as compared to female controls. HDL-Chol of males FDRs was significantly lower as compared to male controls. LDL-Chol of female FDRs was significantly lower than the female controls. No significant difference was observed in the total cholesterol and the triglycerides level of the patients of T2DM and FDRs but those cases in which pre-beta band appear upon lipoprotein electrophoresis had significantly higher triglyceride levels as compared to those patients in which pre-beta band did not appear. CONCLUSION Lipoproteins of the T2DM patients and FDRs group were found to be highly disturbed as compared to the control group and they show a trend of developing atherogenic states in future.
Brome Mosaic Virus 1a Nucleoside Triphosphatase/Helicase Domain Plays Crucial Roles in Recruiting RNA Replication Templates

ABSTRACT Positive-strand RNA virus RNA replication is invariably membrane associated and frequently involves viral proteins with nucleoside triphosphatase (NTPase)/helicase motifs or activities. Brome mosaic virus (BMV) encodes two RNA replication factors: 1a has a C-terminal NTPase/helicase-like domain, and 2apol has a central polymerase domain. 1a accumulates on endoplasmic reticulum membranes, recruits 2apol, and induces 50- to 70-nm membrane invaginations (spherules) serving as RNA replication compartments. 1a also recruits BMV replication templates such as genomic RNA3. In the absence of 2apol, 1a dramatically stabilizes RNA3 by transferring RNA3 to a membrane-associated, nuclease-resistant state that appears to correspond to the interior of the 1a-induced spherules. Prior results show that the 1a NTPase/helicase-like domain contributes to RNA recruitment. Here, we tested mutations in the conserved helicase motifs of 1a to further define the roles of this domain in RNA template recruitment. All 1a helicase mutations tested showed normal 1a accumulation, localization to perinuclear endoplasmic reticulum membranes, and recruitment of 2apol. Most 1a helicase mutants also supported normal spherule formation. Nevertheless, these mutations severely inhibited RNA replication and 1a-induced stabilization of RNA3 in vivo. For such 1a mutants, the membrane-associated RNA3 pool was both reduced and highly susceptible to added nuclease. Thus, 1a recruitment of viral RNA templates to a membrane-associated, nuclease-resistant state requires additional functions beyond forming spherules and recruiting RNA to membranes, and these functions depend on the 1a helicase motifs. The possibility that, similar to some double-stranded RNA viruses, the 1a NTPase/helicase-like domain may be involved in importing viral RNAs into a preformed replication compartment is discussed.
European Banks' Implied Recovery Rates

We examine recovery rates of the European banking sector. To this end, we employ information embedded in credit default swaps (CDS) with different levels of seniority. To estimate implied recovery rates, we extend the model of Schlafer and Uhrig-Homburg (2014) and include absolute priority violation. We fit the extended model and find that the implied recovery rates are much higher than the ones usually applied in pricing formulas. Since the implied recovery rates are estimated from traded instruments, we obtain recovery rates under the so-called pricing measure Q. They incorporate potentially risk premia and differ from physical or historical rates. We also attempt to estimate the impact of the new resolution regulation in the EU on implied recovery rates. When we compare implied recovery rates with historical ones, we observe an underestimation of the recovery risk premium for senior debt and subordinated debt. However, the negative risk premium on subordinated debt has a larger magnitude. Our results are relevant for pricing models of default-prone instruments and risk management practices that require implied recovery and default rates.
Making sense of memory.

The current work explores how people make recognition and belief judgments in the presence of obvious repetition primes. In two experiments, subjects received a 200-ms prime ("cheetah"), either before or after reading a trivia question ("What is the fastest animal? ") but always before being presented with the target answer ("cheetah"). Results showed that repetition priming decreased "old" claims (Recognition--Experiment 1), while it increased truth claims (Belief--Experiment 2). Furthermore, repetition prime placement affected recognition but not belief. Combined, these results suggest that dissociations in memory performance are a natural outcome of task and processing demands and reflect the dynamic, flexible nature of memory.
Effectiveness and Complications Associated With Recombinant Human Bone Morphogenetic Protein-2 Augmentation of Foot and Ankle Fusions and Fracture Nonunions

Background: Recombinant human bone morphogenetic protein-2 (rhBMP-2) has been used to augment bone healing and fusion in a variety of orthopaedic conditions. However, there is a paucity of data evaluating the potential benefits of its use in foot and ankle surgery. The purpose of this study was to investigate the effectiveness and associated complications with the use of rhBMP-2 in high-risk foot and ankle fusions and fracture nonunions. Methods: A total of 51 cases in 48 patients undergoing foot and ankle fusions or fracture nonunion revisions and considered at high risk for subsequent nonunion were identified through a retrospective review in which rhBMP-2 was used as an augment for bone healing. Rate of union, time to union, and associated complications were evaluated. Results: Forty-seven of 51 high-risk cases treated with rhBMP-2 united for a per-case union rate of 92.2%. Seventy-eight of 82 individual sites treated with rhBMP-2 united for a per-site union rate of 95.1%. Of the successful unions, the mean time to union was 111 days (95% confidence interval, 101-121). There were no statistically significant differences in time to union with regard to supplementation with bone allograft or autograft or size of rhBMP-2 kit used. Complication rates were low. Conclusion: rhBMP-2 was a safe and apparently effective adjunct to bony union in high-risk foot and ankle surgeries. Further randomized controlled trials are warranted. Level of Evidence: Level IV, retrospective case series.
“Chaos” In Energy And Commodity Markets: A Controversial Matter

We test whether the futures prices of some commodity and energy markets are determined by stochastic rules or exhibit nonlinear deterministic endogenous fluctuations. As for the methodologies, we use the maximal Lyapunov exponents (MLE) and a determinism test, both based on the reconstruction of the phase space. In particular, employing a recent methodology, we estimate a coefficient $\kappa$ that describes the determinism rate of the analyzed time series. We find that the underlying system for futures prices shows a reliability level $\kappa$ near to $1$ while the MLE is positive for all commodity futures series. Thus, the empirical evidence suggests that commodity and energy futures prices are the measured footprint of a nonlinear deterministic, rather than a stochastic, system.
Ras Proteins Induce Senescence by Altering the Intracellular Levels of Reactive Oxygen Species*

Human diploid fibroblasts eventually lose the capacity to replicate in culture and enter a viable but nonproliferative state of senescence. Recently, it has been demonstrated that retroviral-mediated gene transfer into primary fibroblasts of an activated ras gene (V12ras) rapidly accelerates development of the senescent phenotype. Using thisin vitro system, we have sought to define the mediators of Ras-induced senescence. We demonstrate that expression of V12Ras results in an increase in intracellular and in particular, mitochondrial reactive oxygen species. The ability of V12Ras to induce growth arrest and senescence is shown to be partially inhibited by coexpression of an activated rac1 gene. A more dramatic rescue of V12Ras-expressing cells is demonstrated when the cells are placed in a low oxygen environment, a condition in which reactive oxygen species production is inhibited. In addition, in a 1% oxygen environment, Ras is unable to trigger an increase in the level of the cyclin-dependent kinase inhibitor p21 or to activate the senescent program. Under normoxic (20% O2) conditions, the V12Ras senescent phenotype is demonstrated to be unaffected by scavengers of superoxide but rescued by scavengers of hydrogen peroxide. These results suggest that in normal diploid cells, Ras proteins regulate oxidant production and that a rise in intracellular H2O2 represents a critical signal mediating replicative senescence.
Center-Based Care for Young Children: Examining Predictors of Quality

Abstract The authors collected information from caregivers, trained observers, and parents to investigate quality elements in child-care programs designed for young children in center-based settings. Participants were 75 parents of children aged 15 to 36 months and their caregivers from 13 child-care centers in a southeastern state. Observers collected indicators of program quality and process and structural quality indicators, including adult-child ratio, group size, use of planned activities, use of child-designated space, housekeeping activities, and caregiver-child interactions. Participants responded to questions regarding their child-rearing beliefs, social support networks, perceived stress levels, and demographic characteristics. The best predictors of higher quality care and sensitive caregiver-child interaction in centers were specialized caregiver training, higher adult-child ratios, use of planned activities, and less perceived stress by caregivers. Implications of these findings are discussed.
Reduced NO synthesis and eNOS mRNA expression in endothelial cells from newborns with a strong family history of type 2 diabetes

A deficient synthesis of nitric oxide (NO) may play a role in the early endothelial dysfunction of healthy humans with a strong family history of type 2 diabetes (DM2). In this study, we evaluate the intracellular synthesis of NO and the expression of eNOS transcripts in human umbilical vein endothelial cells (HUVECs), exposed to high glucose concentrations, of healthy newborns with (experimental) and without (control) a strong family history of DM2.
Breaking the Principle of Secrecy: An Examination of Judicial Dissent in the European Constitutional Courts

As “oracles of the law,” judges are trained to provide certainty and guidance within an often-uncertain legal landscape. Nowhere is this statement truer than in the civil law tradition, where the idea of legal certainty has been prized as a “supreme value. ” Despite this tradition, dissenting opinions are now quite common within most European constitutional courts. Using new data from five countries and interviews with constitutional court judges and clerks, I investigate factors that contribute to dissent on constitutional courts. Results indicate that legal and policy characteristics matter, but so do judicial backgrounds and the issues reviewed.
The effect of protein degradation products in grass silages on intake and intake behaviour in sheep

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. The effect of protein degradation products in grass silages on intake and intake behaviour in sheep M Van Os, Jp Dulphy, R Baumont
Otoacoustic emissions in young adults with a history of otitis media

The aim of this study was to investigate otoacoustic emissions in young adults who had a history of otitis media (OM) in childhood and to assess whether a history of OM had an irreversible effect on hearing. We studied 116 cases between 15 and 25 years of age, divided into three groups. Each subject underwent a single examination comprising otoscopy, pure-tone audiometry (PTA), tympanometry, and transient evoked otoacoustic emission (TEOAE) and distortion product otoacoustic emission (DPOAE) testing. Subjects in the first and second groups had normal audiometric hearing thresholds and type A tympanograms. The only difference between the first and second group was the presence or absence of a history of OM. The third group consisted of patients diagnosed as having active OM; these patients had poorer hearing thresholds and type B or C tympanograms. After statistical analysis of TEOAE and DPOAE results (one-way analysis of variance test), significant differences were noted between groups. Otoacoustic emission levels were, unsurprisingly, lowest in the third group, as expected. However, the most striking result in the study was that significantly fewer otoacoustic emissions were detected in subjects with a history of OM than in subjects without a history of OM. These findings suggest that OM in childhood may cause minor but irreversible damage to the middle ear or cochlea. Otoacoustic emissions testing can be used to detect this sub-clinical damage.
Aberrant expression of β-catenin in invasive ductal breast carcinomas.

BACKGROUND AND PURPOSE β-catenin has crucial roles in cell-cell adhesion as well as Wingless (Wnt) signaling pathway, which is closely associated with carcinogenesis. The aim of this study was to evaluate the expression of β-catenin in invasive ductal breast carcinomas and investigate its associations with known clinicopathological parameters, estrogen receptor (ER), progesterone receptor (PR) and tumor proliferative activity then, to explore βcatenin expressional differences in primary tumors and corresponding axillary lymph node metastasis (ALNM). MATERIAL AND METHODS Immunohistochemistry using streptavidin biotin immunoperoxidase method was applied on 65 formalin-fixed paraffin-embedded primary invasive ductal breast carcinomas. Among them, 39 primary tumors (showing LN metastasis) and their corresponding ALNM were further evaluated for differential expression of Βcatenin. Cases were diagnosed during the time period between 2005 to 2007 and retrieved from the archival material of the Pathology Department, Minia University Hospital. RESULTS Of the 65 primary tumors, positive staining for β-catenin was observed in 60 (92.3%) cases with membrane and /or cytoplasmic localization in the examined tumor cells. Reduced membrane expression was significantly associated with advanced stage, lymph node metastasis and negative ER. On the contrary, cytoplasmic localization seemed to be related to an aggressive tumor phenotype where significant associations were identified between high cytoplasmic expression and a large tumor size, a high grade, advanced stage, lymph node positivity, high Ki-67 proliferation index and poor Nottingham Prognostic Index. Membrane βcatenin expression was significantly higher in ALNM compared to their primary where it was significantly reduced with re-expression in ALNM. CONCLUSION β-catenin seemed to have different roles in invasive ductal breast carcinomas, based on its expression levels and subcellular distribution. Altered β-catenin expression in primary tumors with re-expression in nodal metastases is a common event in breast ductal carcinomas and may play a central role in establishing metastasis. These results may offer new insights regarding the role of β-catenin in breast cancer.