Miracle-dz/UniFAR-FTUs huggingface dataset:
Women's Perceptions of the Risks of Age-Related Diseases, Including Breast Cancer: Reports from a 3-Year Research Study

Misperceptions of health risks lead many women to misunderstand their risks and fail to take appropriate measures to prevent or treat many diseases. This article analyzes the impact of various sources of information on the perceptions and misperceptions of women regarding the risks of age-related diseases. This article shows that most of the women respondents held incorrect beliefs about their risk of heart disease, breast and lung cancer, and osteoporosis; half held inaccurate beliefs about disease-related statistical correlation and causation, and about dose-response relations; and many lacked the skills necessary to evaluate media reports about health and medicine. This article indicates that information and education related to health issues, focused on improved public understanding and decision making related to health risks, is needed to achieve improved health outcomes.
Child Behavior Checklist findings further support comorbidity between ADHD and major depression in a referred sample.

OBJECTIVE To examine the convergence of categorical and empirical diagnostic systems to evaluate whether psychiatric comorbidity of juvenile major depression with attention-deficit hyperactivity disorder (ADHD) is due to assessment bias. METHOD Using total predictive value and the odds ratio, the authors evaluated the convergence of Child Behavior Checklist (CBCL) scales with structured interview-derived diagnoses in 94 children with major depression, 97 with ADHD, and 115 normal control children with neither diagnosis. RESULTS The CBCL Anxious/Depressed scale discriminated depressed from nondepressed children irrespective of comorbidity with ADHD, and the Attention Problems scale discriminated ADHD from non-ADHD children irrespective of comorbidity with major depression. Children with major depression comorbid with ADHD had CBCL correlates of both syndromes. CONCLUSIONS Since the CBCL is an empirically derived taxonomic system, the correspondence between the content-congruent CBCL scales and DSM-III-R categorical diagnoses of major depression and of ADHD indicates that previously reported findings of high overlap between these two disorders using structured diagnostic interview methodology and trained raters were not due to rater biases.
PI 3 K Signaling Regulates Rapamycin-Insensitive Translation Initiation Complex Formation in Vaccinia Virus-Infected Cells

How vaccinia virus (VV) regulates assembly of the host translation initiation complex eIF4F remains unclear. Here, we show that VV activated host PI3K to stimulate downstream mammalian target of rapamycin (mTOR), a kinase that inactivates the translational repressor 4E-BP1. However, although the mTOR inhibitor rapamycin suppressed VV-induced inactivation of 4E-BP1, it failed to inhibit eIF4F assembly. In contrast, PI3K inhibition in VV-infected cells increased the abundance of hypophosphorylated 4E-BP1 and disrupted eIF4F complex formation. PI3K signaling, therefore, plays a critical role in regulating protein production during VV infection, at least in part by controlling the abundance and activity of 4E-BP1.
Preliminary studies on immobilized cells-based microbial fuel cell system on its power generation performance

Microbial fuel cell (MFC) is considered an alternative energy production technology that uses the degradation ability of microbes toward organic matters. The resultant products are electrons that will be transferred to the electrode and flows to cathode of the MFC through an external circuit to produce current. The flow of electrons and protons can be channeled to an external circuit to produce electricity. Although the MFC has many advantages, the power density produced is still low. This happens due to high internal resistance cause by electrolyte, the MFC design and the microbes itself. In order to overcome the restriction cause by internal barrier, the present research has focused on developing bio-based anode using microbial cells immobilized in alginate and activated carbon mixture (GAC). In addition, the power production performance was analyzed via single chamber MFC (SCMFC). Through scanning electron microscopic (SEM) observation, the microbes have been successfully embedded into the matrix of alginate. Furthermore, using the GAC, maximum open circuit voltage produced was 403 mV which was higher than a control experiment without the usage of GAC, which achieved 217 mV only after 200 hours operation. In addition, the maximum power densities achieved by the MFC were 0.184mW/m3 for immobilized system and 0.0054mW/m3 for non-immobilized system respectively.
Risk of pyometra in bitches treated for mismating with low doses of oestradiol benzoate

A review of the literature concerning the effect of oestrogens for treating mismating in bitches on the occurrence of pyometra indicated that low doses of oestradiol benzoate substantially increase the incidence of pyometra. A retrospective study of the clinical records of a uk general practice found that the incidence of pyometra in the four months after administration of low doses of oestradiol benzoate was 8·7 per cent, whereas the incidence in the practice's untreated at-risk population was estimated to be less than 1·32 per cent per interoestrus interval, suggesting that more than 85 per cent of pyometras occurring within four months of treatment are iatrogenic.
[Clinical study on treatment of infantile rotaviral enteritis with Psidium guajava L].

OBJECTIVE To observe the clinical effect of olium Psidium guajava (PG) in treating infantile rotaviral enteritis. METHODS Sixty-two patients of rotaviral enteritis were randomly divided into the treated group treated with PG and the control group treated with Gegen Qinlian decoction. The time for ceasing diarrhea, the content of Na+ in blood, the content of Na+ and glucose in stool, and the rate of negative conversion of human rotavirus (HRV) antigen were observed. RESULTS The rate of recovery in 3 days of the treated group was 87.1%, significantly higher than that of the control group (58.1%, P < 0.05). The time of ceasing diarrhea of the treated group (25.1 +/- 9.5 hr) was significantly shorter than that of the control group (38.7 +/- 15.2 hr, P < 0.01). The content of Na+ and glucose in stool was reduced obviously in the treated group, while the reduction in the control group was insignificant, the treated group was superior to the control group significantly (P < 0.05). The rate of negative conversion of HRV in feces of the treated group was 87.1%, significantly better than that of the control (58.1%, P < 0.05). CONCLUSION The treatment with PG has good curative effect on infantile rotaviral enteritis.
Dental Abstracts

PURPOSE To evaluate the biologic width dimensions around implants with nonmatching implant-abutment diameters. MATERIALS AND METHODS Five canines had their mandibular premolars and first molars removed bilaterally and replaced with 12 implants that had nonmatching implant-abutment diameters. On one side, six implants were placed in a submerged surgical approach, and the other side utilized a nonsubmerged approach. Two of the implants on each side were placed either 1 mm above, even with, or 1 mm below the alveolar crest. Two months later, gold crowns were attached, and the dogs were sacrificed 6 months postloading. Block sections were processed for histologic and histomorphometric analyses. RESULTS The bone level, connective tissue length, epithelial dimension, and biologic width were not significantly different when the implants were initially placed in a submerged or nonsubmerged surgical approach. The bone level was significantly different around implants placed 1 mm above the crest compared to implants placed even with or 1 mm below the alveolar crest. The connective tissue dimension was not different for any implant level placement. The epithelial dimension and biologic width were significantly greater for implants placed 1 mm below the alveolar crest compared to implants placed even with or 1 mm above the alveolar crest. For five of six implant placements, connective tissue covered the implant/abutment interface. CONCLUSIONS This study reveals a fundamental change in the biologic response to implants with nonmatching implant-abutment diameters. Unlike implants with matching implant-abutment diameters, the connective tissue extended coronally past the interface (microgap). This morphologic tissue alteration represents a significant change in the biologic reaction to implant-abutment interfaces and suggests that marginal inflammation is eliminated or greatly reduced in these implant designs.
Levels of infection and colonization of some oral bacteria after use of naf, chlorhexidine and a combined chlorhexidine with naf mouthrinses

This study was carried out to evaluate levels of infection of bacteria involved in caries and oral streptococci and their colonization after use of mouthrinses with NaF, chlorhexidine and chlorhexidine plus NaF. Combination of chlorhexidine and fluoride was the only agent that reduced levels of Streptococcus mutans (group) for 30 days.
Interplay between crystal-size and disorder effects in the high-energy optical response of photonic crystal slabs

Experimental reflectance spectra have been obtained for colloidal crystals whose widths ranged from one to several sphere monolayers, and their features in the higher order band energy range have been reproduced theoretically. In order to fit the measured data, optical extinction has been introduced in the theoretical model, which accounts for structure imperfections and disorder, the main sources of losses in an actual measurement. A complex spectrum in the high frequency region is observed even for one ordered monolayer, being this peak structure gradually modified as more layers are piled up. This allowed us to identify which peaks are reminiscent of the optical reflectance features of a single close-packed layer and which are the result of building up a three dimensional periodicity. A clear correlation between the amount of extinction introduced in the fitting and the slab width has been found, which demonstrates that wider real crystals produce less diffusely scattered light. At the same time, we find that the optical response of thinner crystals is more robust against the introduction of extinction than that of thicker ones, for which the effect is dramatic.
Factors predicting the use of breast-conserving therapy in stage I and II breast carcinoma.

PURPOSE To define patterns of care for the local therapy of stage I and II breast cancer and to identify factors used to select patients for breast-conserving therapy (BCT). PATIENTS AND METHODS A convenience sample of 16,643 patients with stage I and II breast cancer treated in 1994 was obtained from hospital-based tumor registries. Histologic variables were determined from original pathology reports. RESULTS BCT was performed in 42.6% of patients. Multivariate analysis demonstrated that living in the Northeast United States (odds ratio [OR], 2.48; 95% confidence interval [CI], 2.16 to 2.84), having a clinical T1 tumor (OR, 2.51; 95% CI, 2.27 to 2.78), and having a tumor without an extensive intraductal component (OR, 2.07; 95% CI, 1.81 to 2.37) were the strongest predictors of breast-conserving surgery. Radiation therapy was given to 86% of patients who had breast-conserving surgery. Age less than 70 years was the most significant predictor of receiving radiation (OR, 2.11; 95% CI, 1.77 to 2.25). Tumor variables did not correlate with the use of radiation, but favorable tumor characteristics were associated with the use of breast-conserving surgery. CONCLUSION Despite strong evidence supporting the use of BCT, the majority of women continue to be treated with mastectomy. Predictors of the use of BCT do not correspond to those suggested in guidelines.
Depressive symptoms and social demographic, stress and health risk behaviour among university students in 26 low-, middle- and high-income countries

Background. The aim of this study was to determine the prevalence and association between depressive symptoms, sociodemographic, social and health risk variables among undergraduate students in 26 low, middle and high income countries. Method. Using anonymous questionnaires, data were collected from 20222 undergraduate university students (mean age 20.8, SD = 2.8) from 27 universities in 26 countries in Africa, Asia, Caribbean and Latin America. Results. Overall study participants had a prevalence of 24.0 % moderate and 12.8 % severe depressive symptoms. In multivariate logistic regression, demographic and social variables (being female gender, low organised religious activity, lack of social support and lack of personal control), stressful or traumatic life events (sexual violence and physical child abuse) and health risk behaviour (tobacco use, insufficient brushing of teeth, irregular sleep duration, increased salt intake, infrequent meals a day, heavy internet use and having sustained an injury) were associated with severe depressive symptoms. Conclusion. High rates of depressive symptoms were found. Several risk factors including social and health risk behaviour variables were identified which can be utilised in guiding interventions.
Field Dependence and the Eysenck Personality Inventory: A Replication

Significant correlations have been described between scores on the extraversion scale of the Ma~tdsley Personality Inventory and field dependence as measured by the Embedded Figures Test (Evans, 1967). Loo ( 1976) has since reported a similar relationship with performance on Form A of the more recent Eysenck Personality Inventory and the Group Embedded Figures Test. This paper describes a replication of Loo's study with the addition of male as well as female subjects. The Embedded Figures Test and Form B of the Eysenck Personality Inventory were administered to 3 3 male and 34 female psychology students ranging in age from 17 to 31 yr. No significant Pearson correlation was found between field dependence and either extraversion (males, r = .22; females, 7 = .03; all, r = .05) or neuroticism (males, r = -.01, females, r = -.25, all, r = -.14). Two-tailed t tests (df = 65) indicated a small but significant sex difference in embedded-figures performance (males, M = 15.24, females, M = 13.09; t = 2.89, p j < .01) but no difference on either Eysenck measure. This greater field independence in males was in line with previous findings and confirmed a specific result with the Group Embedded Figures Test (Witkin, Oltman, Raskin, & Karp, 1971). The lack of a significant correlation between scores on this test and extraversion scores failed to confirm Loo (1976), thereby suggesting that either relationships established with the individual embeddedfigures test do not apply to the group version, or else the inclusion of male subjects or the use of Form B somehow interferred with any correlation Contrary to Loo's (1976) conclusion, the present results do not maintain relationships reported earlier (e.g., Evans, 1967). Rather they suggest that considerably more research is required.
Understanding human papillomavirus vaccination intentions: comparative utility of the theory of reasoned action and the theory of planned behavior in vaccine target age women and men.

INTRODUCTION Human papillomavirus (HPV) is an exceedingly prevalent sexually transmitted infection with serious medical, sexual, and relationship consequences. HPV vaccine protection is available but vaccine uptake is very inconsistent. AIMS This research applies two major theories of health behavior uptake, the Theory of Reasoned Action and the Theory of Planned Behavior, in an effort to understand intentions to receive HPV vaccine among vaccine target age women and men. The Theory of Reasoned Action asserts that attitudes toward HPV vaccination and perceptions of social support for HPV vaccination are the determinants of intentions to be vaccinated, whereas the Theory of Planned Behavior holds that attitudes toward vaccination, perceptions of social support for vaccination, and perceived ability to get vaccinated are the determinants of intentions to be vaccinated. METHODS Canadian university men (N=118) and women (N=146) in the HPV vaccine target age range took part in this correlational study online. MAIN OUTCOME MEASURES Participants completed standard measures of attitudes toward HPV vaccination, perceptions of social support for vaccination, perceived ability to get vaccinated, beliefs about vaccination, and intentions to be vaccinated in the coming semester. RESULTS Findings confirmed the propositions of the Theory of Reasoned Action and indicated that attitudes toward undergoing HPV vaccination and perceptions of social support for undergoing HPV vaccination contributed uniquely to the prediction of women's (R2=0.53) and men's (R2=0.44) intentions to be vaccinated in the coming semester. CONCLUSION Clinical and public health education should focus on strengthening attitudes and perceptions of social support for HPV vaccination, and on the basic beliefs that appear to underlie attitudes and perceptions of social support for HPV vaccination, in efforts to promote HPV vaccine uptake.
The short-term efficacy of bortezomib combined with glucocorticoids for the treatment of refractory lupus nephritis

Objective The treatment of refractory lupus nephritis (LN) remains challenging for clinicians because these patients either do not respond to conventional therapy or relapse during the maintenance treatment period. The aim of this study was to investigate the efficacy and safety of bortezomib combined with glucocorticoids in refractory lupus patients. Methodology Five refractory LN patients aged 21 to 43 years (four females and one male) with biopsy-proven diagnosis (four with type IV and one with type V+IV) were recruited. These patients received bortezomib therapy for four cycles (1.3 mg per square meter of body surface area as an intravenous bolus on days 1, 4, 8, and 11 of 21-day cycles) and glucocorticoids (methylprednisolone 0.5 g/d intravenously for three days, followed by prednisone 0.6 mg/kg/d orally for four weeks, with gradual tapering to 10 mg/d). Proteinuria, serum albumin and creatinine, and immunological parameters were assessed, and adverse effects were also evaluated. Results After two to four bortezomib treatment cycles, four patients achieved partial remission with decreases in SLE disease activity index scores from the range of 12–16 to that of 4–8. The patients also exhibited a decline in proteinuria and an elevation of albumin level after treatment. SCr level was decreased in three of five patients with elevated SCr at baseline. The anti-autoantibodies and complements were also improved. Adverse events were of grades 1–2 and included transient thrombocytopenia, gastrointestinal symptoms and acroesthesia. During a 6- to 24-month follow-up period, three patients achieved complete remission, and one had partial remission. However, one patient received renal replacement therapy. Conclusion Bortezomib combined with glucocorticoids reduces proteinuria, improves renal function and decreases anti-autoantibodies, with good tolerance and mild adverse events, thus representing an alternative therapy for refractory LN and warranting further study.
Electrochemical Comparative Study of Riboflavin, FMN and FAD Immobilized on the Silica Gel Modified with Zirconium Oxide

Eletrodos de pasta de carbono modificados foram preparados pela inclusao de flavinas adsorvidas sobre a silica gel modificada com oxido de zirconio (Si:Zr:flavina). O comportamento eletroquimico de riboflavina, FMN e FAD imobilizadas foi investigado. O potencial formal, Eo´, para as flavinas neste eletrodo foi encontrado como sendo -0,46 V vs. SCE, que e comparavel com os valores obtidos para estas especies em solucao. Alem disso, os valores de Eo´ permaneceram dependentes do pH com certa independencia para riboflavina entre pH 4 e 5. A composicao do eletrolito de suporte nao afetou o Eo´ com excecao de Ca2+, mas em sistemas tampoes e especialmente em fosfato foram verificadas velocidades satisfatorias de transferencia de eletrons. As diferencas observadas no comportamento eletroquimico e espectro de absorcao UV-visivel entre as flavinas imobilizadas foram discutidas em termos de diferentes tipos de interacao.
Direct interactions of coxsackievirus B3 with immune cells in the splenic compartment of mice susceptible or resistant to myocarditis

In vitro replication of coxsackievirus B3 (CVB3) in cells of the immune system derived from uninfected adolescent A/J and C57BL/6J mice and replication of CVB3 in and association with immune cells from spleens of infected animals in vivo were assessed. Nonstimulated or mitogen-stimulated spleen cells were minimally permissive for viral replication during an 8-h period. Three days postinfection (p.i.), CVB3 RNA was localized in vivo to B cells and follicular dendritic cells of germinal centers in both A/J and C57BL/6J mice; however, extrafollicular localization was greater in C57BL/6J mice (P = 0.0054). Although the pattern of CVB3 RNA localization was different, the total load of infections virus (PFU per milligram of tissue) was not different. Splenic CVB3 titers (PFU per milligram of tissue) in both strains were maximal at day 3 or 4 p.i. and were back to baseline by day 7 p.i. , with most infectious virus being non-cell associated. CVB3 titers (PFU per milligram of tissue) correlated directly with in situ hybridization positivity in splenic follicles and extrafollicular regions in both murine strains; however, follicular hybridization intensity was greater in A/J mice at day 5 p.i. (P = 0.021). Flow cytometric analysis demonstrated that 50.4% of total spleen cells positive for CVB3 antigen were B cells and 69.6% of positive splenic lymphocytes were B cells. Myocardial virus load in C57BL/6J mice was significantly lower than that in A/J mice at days 4 and 5 p.i. These data indicate that CVB3 replicates in murine splenocytes in vitro and in B cells and extrafollicular cells in vivo.
Lymphocyte Subpopulations in Patients With Acute Brucellosis

The aim of this work was to evaluate changes in lymphocyte subpopulations, especially helper and cytotoxic T cells, in acute brucellosis patients undergoing treatment. Forty-three acute brucellosis patients were included in the study. Twenty healthy subjects served as controls. Total lymphocytes and the CD3+, CD4+, CD8+, CD19+ and CD (16+56)+ subpopulations were counted by two-color flow cytometric analysis. The CD4+ counts in patients before and after treatment were not statistically different (p = 0.7), but healthy subjects had significantly more of these cells (p = 0.001 and p = 0.001 compared to pre- and post-treatment patients, respectively). The CD8+ counts in acute brucellosis patients decreased after treatment (p = 0.004), but remained higher in both pre- and post-treatment samples than in healthy subjects (p = 0.001 and p = 0.01 respectively). Neither the total leukocyte counts nor the numbers of cells in any subpopulation correlated with blood culture results (positive or negative). No statistically significant differences in the patients' CD4+ T cell counts were observed between the pre-and post-treatment periods, and the count was higher in healthy subjects. Counts of CD8+ T cells increased in acute brucellosis patients, and although they decreased after treatment they remained higher than in the controls. In view of this increase, it was concluded that CD8+ T cells could be the major component in immunity against brucellosis.