Miracle-dz/UniFAR-FTUs huggingface dataset:
Quantitative Data Analysis with IBM SPSS 17, 18 & 19: A Guide for Social Scientists

This latest edition has been fully updated to accommodate the needs of users of SPSS Releases 17, 18 and 19 while still being applicable to users of SPSS Releases 15 and 16. As with previous editions, Alan Bryman and Duncan Cramer continue to offer a comprehensive and user-friendly introduction to the widely used IBM SPSS Statistics. The simple, non-technical approach to quantitative data analysis enables the reader to quickly become familiar with SPSS and with the tests available to them. No previous experience of statistics or computing is required as this book provides a step-by-step guide to statistical techniques, including: Non-parametric tests Correlation Simple and multiple regression Analysis of variance and covariance Factor analysis. This book comes equipped with a comprehensive range of exercises for further practice, and it covers key issues such as sampling, statistical inference, conceptualization and measurement and selection of appropriate tests. The authors have also included a helpful glossary of key terms. The data sets used in Quantitative Data Analysis with IBM SPSS 17, 18 and 19 are available online at http://www.psypress. com/brymancramer; in addition, a set of multiple-choice questions and a chapter-by-chapter PowerPoint lecture course are available free of charge to lecturers who adopt the book.
Validation of the Mindful Self-Care Scale (MSCS) and development of the Brief-MSCS among hospice and healthcare professionals: a confirmatory factor analysis approach to validation

Abstract Objective In the emotionally intense field of healthcare, the ability to peacefully inhabit one's body, maintain good boundaries, and be fully present during care is essential. This study aimed to validate the recently developed Mindful Self-Care Scale (MSCS) among hospice and healthcare professionals and develop a brief version of the 33-item MSCS. Method A sample of hospice and healthcare professionals from all 50 states (n = 858) was used. A confirmatory factor analysis was run using a rigorous methodology for validation and item reduction to develop a brief version of the 33-item MSCS. The brief MSCS (B-MSCS) was developed by identifying items for exclusion through examination of conceptual overlap, descriptive statistics by detecting sources of improvement model fit using confirmatory factor analysis. Model modifications were done sequentially and with regard to theoretical considerations. Result The existing model, 33-item MSCS with six subscales, had good fit to the data with all indicators in acceptable ranges (chi-square/df = 3.08, df (480), p < 0.01, root mean square error of approximation = 0.059, comparative fit index = 0.915, Tucker and Lewis's index of fit = 0.907). Nine items were excluded on the basis of very low loadings and conceptual and empirical overlap with other items. Significance of results The final 24-item, B-MSCS model was consistent with the original conceptual model and had a closer fit to the data (chi-square/df = 1.85, df (215), p < 0.01, root mean square error of approximation = 0.041, comparative fit index = 0.961, Tucker and Lewis's index of fit = 0.955). In addition, the reliability, construct, and concurrent validity of the MSCS and B-MSCS were in the acceptable and good ranges, respectively. Mean and standard deviation of the MSCS and B-MSCS scores were similar; B-MSCS mean scores well approximated the MSCS scores. Informal mindful self-care, in the process of everyday life, was practiced more regularly and associated with increased wellness and reduced burnout risk than formal mind-body practices.
Associations Between Boys' Early Childhood Exposure to Family and Neighborhood Poverty and Body Mass Index in Early Adolescence.

OBJECTIVE To test relations between exposure to poverty, in the forms of family income and neighborhood deprivation, during three developmental stages, and children's body mass index (BMI) in early adolescence. METHODS Data came from a longitudinal sample of racially diverse, urban, low-income boys. Interactions between family income to needs and census-derived neighborhood deprivation at three developmental stages-early childhood (18 and 24 months), preschool-to-school entry (3.5 and 6 years), and school-age (8 and 10 years)-were tested in relation to BMI at age 11. RESULTS There was a significant interaction whereby higher income predicted lower BMI only in the context of low levels of neighborhood deprivation in early childhood. In high-deprivation neighborhoods, higher income was associated with risk for overweight/obesity in early adolescence. This pattern was found to be specific to income and neighborhood deprivation measured in early childhood. CONCLUSIONS Findings have implications for policy relevant to obesity prevention. More research on associations between early exposure to poverty and later risk for obesity on low-income samples is warranted, as the relationship is likely complex and influenced by many different factors, including the family and neighborhood food environments and child health behaviors.
Emotional Processing and Personality as Predictors of Obsessive-compulsive Symptoms in College Students

Abstract The categorical definition of obsessive-compulsive disorder, and exclusive focus on thoughts and behaviors, have constrained the study and treatment of its symptoms. The present study’s aim was to search for relationships among emotional processing dimensions, five major personality dimensions, and self-perceived obsessive-compulsive symptoms. The participants were 100 college students, and the questionnaires used were a selection of images from the International Affective Picture System (IAPS), the Self-assessment Manikin (SAM), the Dimensional Obsessive-Compulsive Scale (DOCS), and the NEO-FFI. We found differences in emotional processing dimensions between participants with high and low DOCS scores, grouped according to sex (d = .56); and evidence that the neuroticism and agreeableness dimensions predict self-perceived obsessive-compulsive symptoms. Emotional processing dimensions and personality are considered useful to comprehending obsessive-compulsive symptoms, which lends support to dimensional models of OC symptomatology, as well as planning and developing psychological interventions.
Pneumonitis and concomitant bacterial pneumonia in patients receiving pembrolizumab treatment

Abstract Rationale: Pembrolizumab, a monoclonal antibody against the programmed cell death 1 (PD-1) protein, can induce a stable regression of some malignancies refractory to conventional chemotherapy. Despite such therapeutic benefits, pembrolizumab can induce immune-related adverse events, with pneumonitis being the most critical problem. Patient concerns: All 3 patients complained of fever, cough, and dyspnea after a variable time interval (1–21 days) from pembrolizumab treatment. Diagnoses: Chest computed tomography invariably showed ground glass opacity. All tests for possible infectious agents were negative. Based on high procalcitonin level, one of 3 patients was diagnosed to have accompanying bacterial pneumonia. Interventions: All patients received antibiotics and steroid treatments (methylprednisolone, 1 mg/kg). Outcomes: The 3 patients showed different clinical courses ranging from mild pneumonitis to rapidly progressing respiratory failure. Among the 3 patients, 2 fully recovered with steroid treatment; 1 died from superimposed bacterial pneumonia. Lessons: The prognosis of pembrolizumab-induced pneumonitis with a superimposed bacterial pneumonia would be poor. It is important to distinguish pure pneumonitis from that with a superimposed bacterial pneumonia.
A pilot intervention to reduce postpartum weight retention at primary health care in Brazil.

BACKGROUND postpartum weight retention (PWR) strongly predicts obesity, the major nutritional concern of this century; however, there is a gap in nutritional care for postpartum women in Brazil. OBJECTIVE to evaluate the effect of nutritional counselling provided at primary health care on the reduction of PWR. METHOD pilot study carried out in a low-income community in southeastern Brazil, involving postpartum women with PWR, who were provided with individual monthly appointments with a nutritionist over three months of follow-up. Nutritional counselling was based on the Dietary Approach to Stop Hypertension (DASH diet) aiming at healthy and gradual weight loss. Anthropometric evaluation included measurement of weight, height, waist circumference and percentage of body fat. Dietary intake was assessed using a food frequency questionnaire and adherence to diet was evaluated using a DASH score. RESULTS women who participated in the study (n = 26) showed a reduction in PWR (median -1.80 kg, p = 0.004), body mass index (-0.57 kg/m², p = 0.004), and waist circumference (-2.50 cm, p = 0.024), as well as 91.67% of them presented good adherence to diet. CONCLUSION nutritional counselling provided to low-income postpartum women at primary health care contributed to the reduction of PWR, body mass index and waist circumference, as the study participants presented good adherence to a healthy dietary pattern.
Comparison of early postoperative recovery between laryngeal mask airway and endotracheal tube in laparoscopic cholecystectomy

Abstract Background: Laryngeal mask airway (LMA) insertion provokes fewer stress responses than endotracheal intubation. This study aimed to evaluate the LMA Protector for assessing improvements in intraoperative hemodynamic stability and to reduce postoperative discomfort compared with endotracheal intubation in laparoscopic cholecystectomy. Methods: Fifty-six patients who underwent laparoscopic cholecystectomy while under sevoflurane-based general anesthesia were randomly allocated to airway management using LMA (LMA group) or endotracheal tube (ETT group). Heart rate, blood pressure, and peak airway pressure were recorded before and after carboperitoneum. Postoperative pain and analgesic requirements were assessed, in addition to nausea, hoarseness, dysphonia, and sore throat during the first 1 hour postoperatively and until postoperative day 1. Results: All patients underwent successful LMA or ETT placement within 2 attempts. There was no difference in highest mean (SD) peak airway pressure during carboperitoneum between the LMA and ETT groups (17.7 [2.8] mm Hg vs 19.1 [3.8] mm Hg, P = .159, respectively). The incidence of high systolic blood pressure and bradycardia was higher in the LMA group. The highest pain scores 1 hour postoperatively and on postoperative day 1 were lower in the LMA group than in the ETT group (3.9 [2.0] vs 5.4 [2.3], P = .017 and 5.6 [1.9] vs 6.7 [1.7], P = .042, respectively); requirements for analgesics were similar in the 2 groups. The incidence of nausea was lower in the LMA group than in the ETT group until postoperative day 1 (4/28 [14%] vs 12/28 [43%], P = .031, respectively). Conclusion: The LMA Protector was an effective ventilator device associated with fewer intraoperative hemodynamic stress responses and improved the quality of early recovery after laparoscopic cholecystectomy.
Cellular Microbiology: The metabolic interface between host cell and pathogen

Cellular Microbiology has benefited greatly from the use of immortalized cell lines as host cells for tissue culture models of infection. However, these cells lack many important characteristics of the different cell lineages that are found in vivo. This deficiency is particularly true of macrophages that we now know derive from several distinct ontogenic lineages. This perspective discusses these challenges and possible approaches to overcome them.
Deoxyshikonin isolated from Arnebia euchroma inhibits colorectal cancer by down-regulating the PI3K/Akt/mTOR pathway

Abstract Context: Shikonins, a series of natural occurring naphthoquinones extracted from Arnebia euchroma (Royle) Jonst. (Boraginaceae), have antitumor activities and low toxicity. Objective: To illuminate potential activity and mechanism of shikonins against colorectal cancer (CRC). Materials and methods: Five shikonins were isolated from A. euchroma, and elucidated by extensive spectroscopic analysis. Anti-proliferative activities of shikonins (0–100 μg/mL) on human colorectal cells were evaluated by MTT and CCK-8 for 24 or 48 h. Cell apoptosis and cycle distribution were examined by FCM analysis. The expression of PI3K/Akt/mTOR pathway mRNAs and proteins was analysed by RT-PCR and Western blot, respectively. Cell viability, cell apoptosis, cell cycle and protein expression were measured, when co-treated with PI3K/Akt/mTOR pathway inhibitors. The in vivo activity of deoxyshikonin was evaluated using xenograft tumour model. Results: Deoxyshikonin and another four shikonins were isolated and identified. Deoxyshikonin exhibited anti-proliferative activity with IC50 of 10.97 μM against HT29 cells. Moreover, the percentage of early apoptotic cells and G0/G1 cells increased from 1 to 29% and 44 to 67% with 0–50 μg/mL deoxyshikonin, respectively. Deoxyshikonin also down-regulated the expression of PI3K, p-PI3K, Akt, p-Akt308 and mTOR proteins in HT29 and DLD-1 cells. Moreover, LY294002, NVP-BEZ235 and MK-2206 can make deoxyshikonin more cell proliferation inhibited, cell cycle arrested at G0/G1 and apoptosis promoted. In vivo study, the weight of tumour tissues at deoxyshikonin groups was significantly reduced compared with the control group, and PI3K, p-PI3K, Akt, p-Akt308 and mTOR expression was decreased. Discussion and conclusions: We can conclude that deoxyshikonin isolated from Arnebia euchroma inhibited CRC through the PI3K/Akt/mTOR pathway.
DEMOGRAPHICS, COMPLICATIONS AND RESOURCE UTILIZATION FOR PATIENTS HOSPITALIZED FOR MEASLES ACROSS US CHILDREN'S HOSPITALS.

Our objective was to retrospectively describe measles hospitalizations in 52 US children's hospitals. We identified 136 patients hospitalized for measles in 2004-2018; 17% (23/136) had complex chronic conditions, 2 of whom died or were in hospice. Among noncomplex patients only 39% received vitamin A, median length of stay was 3 days and median adjusted estimated costs were $5896.
An optimal scheduling policy for fork/join queues

We consider the problem of optimally scheduling an arriving job on a set of homogeneous single-server queues: (i) arriving jobs consist of a random number of tasks which can be executed independently of each other; (ii) a job is completed only after all of its component tasks have finished execution; and (iii) a central dispatcher schedules the tasks on the queues at job arrival instants using information on the number of tasks currently scheduled on each processor. In the case of two queues when task are exponentially distributed, we show that the individually optimal policy is a mixture of policies corresponding to sequential job execution (all tasks are scheduled on a single processor) and parallel scheduling (tasks are distributed among several queues in a manner that tends to equalize queue lengths). Under conditions that include the case of moderate to heavy loads, the individually optimal scheduler is shown to schedule tasks according to the sequential policy. The conclusions obtained in this special case hold generally for an arbitrary number of processors and general task service time distribution. <<ETX>>
Relationships among measures of physical fitness in adult patients with heart failure.

OBJECTIVES To describe the relationships among 3 measures of physical fitness (exercise capacity, muscle function and functional capacity) in patients with heart failure, and to determine whether these measures are influenced by impairment of movement. METHODS Secondary analysis of baseline data from the Italian subsample (n = 96) of patients with heart failure enrolled in a randomized controlled trial, the HF-Wii study. Exercise capacity was measured with the 6-min walk test, muscle function was measured with the unilateral isotonic heel-lift, bilateral isometric shoulder abduction and unilateral isotonic shoulder flexion, and functional capacity was measured with the Duke Activity Status Index. Principal component analysis was used to detect covariance of the data. RESULTS Exercise capacity correlated with all of the tests related to muscle function (r = 0.691-0.423, p < 0.001) and functional capacity (r = 0.531). Moreover, functional capacity correlated with muscle function (r = 0.482-0.393). Principal component analysis revealed the bidimensional structure of these 3 measures, thus accounting for 58% of the total variance in the variables measured. CONCLUSION Despite the correlations among exercise capacity, muscle function and functional capacity, these measures loaded on 2 different factors. The use of a wider range of tests will help clinicians to perform a more tailored assessment of physical fitness, especially in those patients with heart failure who have impairment of movement.
Cytotoxic p-terphenyls from the deep-sea-derived Aspergillus candidus

Abstract From the deep-sea-derived fungus Aspergillus candidus, one novel (1) and three known (2–4) p-terphenyl derivates were isolated. The structure of the new compound was established mainly on the basis of extensive analysis of 1D and 2D NMR data. All four isolates were tested for in vitro anti-food allergic and antitumor bioactivities. Compounds 3 and 4 showed potent antiproliferative effect against four cancer cells of Hela, Eca-109, Bel-7402, and PANC-1 with IC50 values ranging from 5.5 μM to 9.4 μM. GRAPHICAL ABSTRACT
Teaching Methodology and its Effects on Quality Learning.

Teaching method is the mechanism that is used by the teacher to organize and implement a number of educational means and activities to achieve certain goals. Teaching techniques are the means that reflect the success of the learning process and the competencies of the teacher. Being a teacher, I always need to look for new ways to deliver knowledge to my learner, and in many occasions, I found that traditional teaching methods become not effective as it used to be due to the current advancement in technology. Teaching becomes more effectives when it performed in a quicker response to the needs of the learner, so that blending various techniques to deliver knowledge and ideas become necessary. This paper presents the characteristics of many teaching methods including online teaching and a comparison between them is highlighted, in order to choose the method that satisfy the aims and provide the teacher with high competency. Keywords: Teaching Methodology, Competency, Strengths and Limitations, Quality of Teaching, Online Learning.
MepmiRDB: a medicinal plant microRNA database

Abstract MicroRNAs (miRNAs) have been recognized as a key regulator in plant development and metabolism. Recent reports showed that the miRNAs of medicinal plants not only act as a critical modulator in secondary metabolism but also had a great potential of performing cross-kingdom gene regulation. Although several plant miRNA repositories have been publicly available, no miRNA database specific for medicinal plants has been reported to date. Here, we report the first version of MepmiRDB (medicinal plant microRNA database), which is freely accessible at http://mepmirdb.cn/mepmirdb/index.html. This database accommodates thousands of miRNA candidates belonging to 29 medicinal plant species. The miRNA information on sequences, expression patterns and regulatory networks has been included in the functional modules of the database. Specifically, the ‘Sequence’ module provides the sequences of the mature miRNAs and their precursors, and the structure information of the precursors. Moreover, the processing and small RNA accumulation signals on the miRNA precursors are also included in the ‘Sequence’ module. The organ/growth condition-specific expression information of the mature miRNAs has been stored in the ‘Expression’ module. The ‘Interaction’ module offers the information of the degradome-validated miRNA—target pairs of eight plant species. The ‘Search’ module enables users to search for the miRNAs by plant species and miRNA families, or by sequences. All data in this database are available for download. Taken together, the functional modules of MepmiRDB ensure its importance and timeliness for mechanistic and functional studies on the medicinal plant miRNAs.
Motion planning using a colored Kohonen network

Figure 14: The success rate for three diierent scenes, set against the number of learning steps. generalizable to higher-dimensional connguration spaces without major changes of the algorithm. Furthermore it is quite fast; it typically takes only a few seconds to compute a motion, and we expect that a more careful implementation can improve this even further. Finally, the resulting motions are relatively short and smooth, thus eliminating the need for additional (time-consuming) path smoothing. The generalization of the method to higher dimensions should be straightforward. However, it could still be improved in a number of details, such as a more powerful algorithm for nding a partial motion between two nodes. Also a complexity analysis would be interesting. References 1] D. Desieno. Adding a conscience to competitive learning. 3] B. Fritzke. Let it grow | self-organizing feature maps with problem dependent cell structure. be explained by considering the size of the rotating robot in terms of the size of the connguration space. A full rotation of an average size robot occupies only a small part of the connguration space when compared to e.g., moving it from x = 0 to x = 1. Therefore an initial grid size of 4 in the dimension already allows for a better precision in that dimension than a grid of size 10 in the x and y dimension. To test the learning behavior of the network, 100 source and goal conngurations were randomly chosen. The success rate for a scene is deened as the relative number of these conngurations between which the program is able to construct a path. Note that this can only be equal to 1:0 if the connguration space consists of only one connected component. Figure 14 shows the success rate for Scenes 1, 4, and 5, set against the number of learning steps. The results for Scene 1 are indicated with a dotted line. The networks performance very quickly converges towards a success rate of 1.0, indicating it perfectly`knows' the whole scene. In the case of Scene 5 (shown with a dashed line), the network converges quickly, but towards a success rate of only 0.95. This can be explained by the fact that the scene contains conngurations from which the robot cannot escape (e.g., the small part of free space in the upper right corner). The same applies to Scene 4 (shown with a solid line) where the performance converges towards …