Miracle-dz/UniFAR-FTUs huggingface dataset:
A comparative analysis of radiographer versus radiologist in the diagnosis of rotator cuff tears of the shoulder using ultrasound

License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress. com/permissions.php Orthopedic Research and Reviews 2015:7 131–135 Orthopedic Research and Reviews Dovepress
Effect of Rosemary Transglutaminase on Yoghurt Fortified with Whey Protein Isolate

Abstract Rosemary (Rosmarinus officinalis L.) transglutaminase (RTGase) was used to cross-link whey protein isolate (WPI) and its ability to induce gelation was investigated. The rheological and textural properties of WPI were improved with RTGase treatment. Set-type yoghurts fortified with 1% WPI powder treated with RTGase at the level of 2.5 and 10 unit/g protein were studied. Chemical, rheological, textural and organoleptic properties of the yoghurt treated with RTGase were better than these of the control yoghurt.
1 Mimiviridae : a rising family of highly diverse large 2 aquatic dsDNA viruses infecting a wide variety of 3 eukaryotes . 4

Since 1998, when Jim van Etten’s team initiated its characterization, Paramecium bursaria 14 Chlorella virus 1 (PBCV-1) had been the largest known DNA virus, both in terms particle size and 15 genome complexity. In 2003, The Acanthamoeba-infecting Mimivirus unexpectedly superseded 16 PBCV-1, opening the era of giant viruses, i.e. with virions large enough to be visible by light 17 microscopy and genomes encoding more proteins than many bacteria. During the 15 following 18 years, the isolation of many Mimivirus-relatives, have made the Mimiviridae one of the largest and 19 most diverse family of eukaryotic viruses isolated from aquatic environments. Metagenomic studies 20 keep suggesting that many more remain to be isolated. As Mimiviridae members are found to infect 21 an increasing range of phytoplanckton species, their taxonomic position compared to the traditional 22 Phycodnaviridae (i.e. etymologically “algal viruses”) became a source of confusion in the literature. 23 Following a rapid history of the key discoveries that established the Mimiviridae family, we 24 describe its current taxonomic structure and propose a set of operational criteria to help in the 25 classification of future isolates. 26
Structural studies of Erwinia carotovora L-Asparaginase by X-ray crystallography

Bacterial L-asparaginases (E.C.3.5.1.1) are enzymes that catalyze the hydrolysis of L-asparagine to aspartic acid. For the past 30 years these enzymes have been used as therapeutic agents in the treatment of acute childhood lymphoblastic leukemia. The presence of a low rate glutaminase activity however causes serious side-effects to patients in treatment, as glutamine depletion give rise to neurotoxicity, anaphylaxis, and other hypersensitivity reactions. The interest in the enzyme from Erwinia carotovora originates from the fact that it shows a decreased glutaminase activity, and therefore the enzyme is expected to exhibit fewer side effects when used in therapy.The main focus of this thesis is the crystal structure determination of L-asparaginase from Erwinia carotovora in the presence of aspartic acid at 2.5 A resolution. The structure was refined to an R/Rfree factor of 19.9/28.6 with good stereochemistry.L-Asparaginases are homotetrameric enzymes with a known 222 symmetry and an identical fold. The Erwinia carotovora asparaginase consists of eight monomers of 330 amino acid residues each. In this case the enzyme is active as a dimer of tetramers. The two tetramers have an inner twofold non-crystallographic symmetry. Each monomer forms two identifiable domains a large N-domain and a small C-domain. The active sites are found at a topological switch-point between those domains.
Overexpression of HOXB 7 is associated with a poor prognosis in patients with gastric cancer

Previous studies have indicated that the homeobox gene HOXB7 is overexpressed in certain cancers, which promotes tumorigenesis. However, less is known about the association between the HOXB7 gene and gastric cancer. The purpose of the present study was to investigate the association between the expression level of HOXB7 and gastric cancer. Reverse transcription-quantitative polymerase chain reaction and western blot analysis were used to detect the expression of the homeobox B7 (HOXB7) RNA and protein, respectively. In addition, the association between the expression of HOXB7 and the clinicopathological characteristics of gastric cancer was analyzed by immunohistochemistry. The Kaplan-Meier method was used to calculate the survival rates, and the COX proportional hazards model was used to investigate univariate and multivariate analyses. The expression level of HOXB7 RNA and protein was significantly elevated in cancerous tissues compared with the corresponding normal mucosa. Increased expression of HOXB7 was significantly associated with tumor size (P=0.01), T stage (P<0.001) and advanced Union for International Cancer Control stage (P=0.003). In addition, patients with positive HOXB7 expression possessed an evident lower overall survival and disease-free survival rate compared with patients with tumors that did not express HOXB7. Furthermore, univariate and multivariate analyses indicated that HOXB7 served as a significant independent prognostic factor for OS and DFS in patients with gastric cancer. The present data indicate that the HOXB7 gene may play an important role in the process of gastric tumorigenesis, and also indicate that HOXB7 may be an important determinant of patient prognosis in gastric cancer.
Financial Indicators and Density Forecasts for US Output and Inflation

When do financial markets help in predicting economic activity? With incomplete markets, the link between financial and real economy is state-dependent and financial indicators may turn out to be useful particularly in forecasting "tail" macroeconomic events. We examine this conjecture by studying Bayesian predictive distributions for output growth and inflation in the US between 1983 and 2012, comparing linear and nonlinear VAR models. We find that financial indicators significantly improve the accuracy of the distributions. Regime-switching models perform better than linear models thanks to their ability to capture changes in the transmission mechanism of financial shocks between good and bad times. Such models could have sent a credible advance warning ahead of the Great Recession. Furthermore, the discrepancies between models are themselves predictable, which allows the forecaster to formulate reasonable real-time guesses on which model is likely to be more accurate in the next future.
Socioeconomic value of orthopedic devices: evidence and methodological challenges

Correspondence: Corinna Sorenson LSE Health, London School of Economics and Political Science, London, UK Tel +44 (0)20 7955 7397 Fax +44 (0)20 7955 6803 Email c.sorenson@lse.ac. uk Abstract: With continued technological advances in orthopedic devices and increasingly limited health care resources, greater attention will be placed on substantiating the socioeconomic value of these devices. Therefore, this study focused on a systematic review of available economic evaluations of selected orthopedic devices (n = 33 studies) to assess their impact on different clinical and economic outcomes. The existing evidence suggests that they have important benefits to patients, including reduced risk of fractures, increased mobility and functioning, and enhanced quality of life, and do so cost effectively or with cost savings. However, we have identified several methodological obstacles to sufficient ascertainment of value, such as a lack of robust information on health economic outcomes and long-term evidence. We also identify areas where additional research is needed to assess more fully the value of orthopedic devices.
Submitted to the Annals of Statistics AN OPERATOR THEORETIC APPROACH TO NONPARAMETRIC MIXTURE MODELS By

When estimating finite mixture models, it is common to make assumptions on the mixture components, such as parametric assumptions. In this work, we make no distributional assumptions on the mixture components and instead assume that observations from the mixture model are grouped, such that observations in the same group are known to be drawn from the same mixture component. We precisely characterize the number of observations n per group needed for the mixture model to be identifiable, as a function of the number m of mixture components. In addition to our assumption-free analysis, we also study the settings where the mixture components are either linearly independent or jointly irreducible. Furthermore, our analysis considers two kinds of identifiability – where the mixture model is the simplest one explaining the data, and where it is the only one. As an application of these results, we precisely characterize identifiability of multinomial mixture models. Our analysis relies on an operator-theoretic framework that associates mixture models in the grouped-sample setting with certain infinite-dimensional tensors. Based on this framework, we introduce a general spectral algorithm for recovering the mixture components.
WOOD ANATOMY OF THE GENUS EUPLASSA AND ITS RELATION TO OTHER PROTEACEAE OF THE GUIANAS AND BRAZIL

Three genera of the Proteaceae belonging to the tribe Grevilleeae occur in the Guianas and Brazil: Roupala, Panopsis, and Euplassa. The microscopical wood structure of one of these genera, Euplassa, has not been described before. Anatomically it proves to be nearly identical with Panopsis which it also resembles in general properties. Roupala differs in several respects. Within the genera differences are not fundamental and chiefly a matter of numbers and dimensions. A key to the genera is given. The relation of these three genera with the two other members of the tribe in South America, Orites and Gevuina, is discussed.
on Association between SCD 1 and OLR 1 Genes

Quantitative traits are controlled by large numbers of genes and also influenced by environmental factors. Recent researches with farm animals have quantified the effect of candidate genes on economically important traits. Identification of genes with large effects on milk production traits would be useful for genetic improvement programs in dairy cattle (Wang et al. 2016; Cecchinato et al. 2015; Hosseinpour et al. 2013). Stearoyl-CoA desaturase (SCD) is an enzyme that plays an important role in the biosynthesis of fatty acids. This enzyme belongs to a large family of enzymes that are involved in the synthesis of saturated fatty acids and they are found in both animals and plants. Stearoyl-CoA desaturase (SCD) is the enzyme responsible for conversion of saturated fatty acids into 9monounsaturated fatty acids in mammalian adiposities (Campbell et al. 2001; Taniguchi et al. 2004). Two SCD isoforms are known in cattle, SCD5 is expressed in brain and is located on chromosome 6 and SCD1 is located on The present study was carried out to investigate the association of C/T single nucleotide polymorphism (SNP) in exon 5 of stearoyl-CoA desaturase 1 (SCD1) gene and A/C SNP in the 3' untranslated region of oxidized low density lipoprotein receptor 1 (OLR1) gene with milk production traits in Iranian Holstein dairy Cattle. The blood samples of 153 (for OLR1) and 308 (for SCD1) dairy cattle from three different farms were used for genotyping. A 146 bp fragment of 3'UTR of OLR1 gene and a 400 bp fragment of exon 5 of SCD1 gene were amplified by standard PCR. Single nucleotide polymorphism of OLR1 and SCD1 gene was determined by polymerase chain reaction single-restriction fragment length polymorphism (PCRRFLP) technique. The association between genotypes of OLR1 and SCD1 genes with milk production traits was studied by general linear models (GLM) procedure of SAS package and Duncan test was used for comparing means of traits. The frequency of AA, AV and VV genotype of SCD1 gene were 0.60, 0.32 and 0.08 respectively. The frequency of alleles A and V were 0.76 and 0.24. The genotype frequencies of AA, AC and CC in OLR1 gene were 0.22, 0.50 and 0.28 respectively. The frequency of allele A and C was 0.47 and 0.53. Thus, this population was in Hardy-Weinberg equilibrium for OLR1 but not for SCD1. The means of fat percentage for SCD1 genotypes were 3.43% and 3.33 for VV and AA respectively (P<0.05). The means of OLR1 genotypes were 8273 kg (CC), 8344 kg (AC) and 7178 kg (AA) for milk yield; 276.3 kg (CC), 277.6 kg (AC) and 239.7 kg (AA) for fat yield and for protein yield were 286.7 kg (CC), 290.5 kg (AC) and 253 kg (AA) (P<0.05). The results revealed these two SNP are appropriate for marker assisted selection.
Testing gridded land precipitation data and precipitation and runoff reanalyses (1982–2010) between 45° S and 45° N with normalised difference vegetation index data

The realistic simulation of key components of the land-surface hydrological cycle – precipitation, runoff, evaporation and transpiration, in general circulation models of the atmosphere – is crucial to assess adverse weather impacts on environment and society. Here, gridded precipitation data from observations and precipitation and runoff fields from reanalyses were tested with satellite derived global vegetation index data for 1982–2010 and latitudes between 45° S and 45° N. Data were obtained from the Climate Research Unit (CRU), the Global Precipitation Climatology Project (GPCP) and Tropical Rainfall Monitoring Mission (TRMM; analysed for 1998–2010 only) and precipitation and runoff reanalyses were obtained from the National Centers for Environmental Prediction/National Center for Atmospheric Research (NCEP/NCAR), the European Centre for Medium-Range Weather Forecasts (ECMWF) and the NASA Global Modelling and Assimilation Office (GMAO). Annual land-surface precipitation was converted to annual potential vegetation net primary productivity (NPP) and was compared to mean annual normalised difference vegetation index (NDVI) data measured by the Advanced Very High Resolution Radiometer (AVHRR; 1982–1999) and Moderate Resolution Imaging Spectroradiometer (MODIS; 2001–2010). The effect of spatial resolution on the agreement between NPP and NDVI was investigated as well. The CRU and TRMM derived NPP agreed most closely with the NDVI data. The GPCP data showed weaker spatial agreement, largely because of their lower spatial resolution, but similar temporal agreement. MERRA Land and ERA Interim precipitation reanalyses showed similar spatial agreement to the GPCP data and good temporal agreement in semi-arid regions of the Americas, Asia, Australia and southern Africa. The NCEP/NCAR reanalysis showed the lowest spatial agreement, which could only in part be explained by its lower spatial resolution. No reanalysis showed realistic interannual precipitation variations for northern tropical Africa. Inclusion of runoff in the NPP prediction resulted only in marginally better agreement for the MERRA Land reanalysis and slightly worse agreement for the NCEP/NCAR and ERA Interim reanalyses.
Single molar restoration Wide implant versus two conventional

implant with standard abutment (Nobel Biocare). 1 _The single-tooth restoration has become one of the most widely used procedures in implant dentistry.1 In the posterior region of the oral cavity, bone volume and density are often compromised. Occlusal forces are greater in this region and, with or without parafunctional habits, can easily compromise the stability of the restorations (Fig. 1). 2, 3
Acute Effects of Stretching on Flexibility, Power and Sport Specific Performance in Fencers

Acute Effects of Stretching on Flexibility, Power and Sport Specific Performance in Fencers Elite athletes are eager to perform to the best of their ability, regardless of different warm-up stretching techniques used before training or competition which actually help or hinder specific performance variables. The aim of this study was to investigate the acute effects of static or ballistic stretching on flexibility and leg power characteristics of fencing performance in fencers of both genders. Ten male and ten female international level fencers participated in this study. Each subject performed static or ballistic stretching (3 sets of 20 sec) on three muscles of the lower limbs on separate days. Flexibility, squat jump, countermovement jump, drop jump, time and power of lunge and shuttle run test were measured before and after different stretching interventions. Neither static nor ballistic stretching exercises affected flexibility, jumping ability and leg functional fencing performance tests. Moreover, stretching conditions did not affect differently. The results of this study suggest that static or ballistic stretching in the later stages of a general warm-up normally used before training or competition does not hinder specific performance in fencing. Consequently, fencers can continue performing any type of stretching before training or competition at their preference.
Technology and Institutions: Theoretical Aspects of Institutional Innovation and its Deficiency in Haiti

In the recent decades, in Haiti, a growing propensity to accept new technologies is observed. More than ever, the national market represents a potential advantage, as well as the cheapness of the labor force. Meanwhile, the country cannot take plenty advantage of its technological development potential in order to stimulate the economic growth. The paper analyzes the disadvantage factors. The conclusion show that in addition to the low level of education and the expatriation of skilled human resources, institutional characteristics may help to understand the ineffectiveness of economic development strategies implemented in Haiti in recent years. Then, we propose institutional innovation as both an analytical framework and a challenge to understand and foster economic development through technology in Haiti.
Type of the Paper ( Review ) 1 Computing the Effect of Environmental Damage on 2 Aircraft Structural Integrity 3

This paper studies the combined effect of corrosion and fatigue on the growth of cracks in 14 aircraft and on the effect of skin corrosion and stress corrosion cracking on the load bearing 15 capacity of rib stiffened aircraft wings. In this context it is shown that the growth of cracks from 16 surface pitting, and also from intergranular cracking at a fastener hole, can be accurately computed 17 using the Hartman-Schijve variant of the NASGRO crack growth equation. The examples studied 18 support the lead crack approach, that has been independently developed by the USAF and the 19 Australian Defence Science Technology Group, in which the growth of lead cracks is often 20 exponential. In the case of skin corrosion it is shown that to be consistent with the US Joint Service 21 Structural Guidelines (JSSG2006) assessment of its effect on the load bearing capacity of the wing 22 should involve an assessment of whether at 115% DLL the remaining material exceeds the yield 23 stress of the material. 24
Self–Compassion is Best Measured as a Global Construct and is Overlapping with but Distinct from Neuroticism: A Response to Pfattheicher, Geiger, Hartung, Weiss, and Schindler (2017)

Pfattheicher and colleagues recently published an article entitled ‘Old Wine in New Bottles? The Case of Self–compassion and Neuroticism’ that argues the negative items of the Self–compassion Scale (SCS), which represent reduced uncompassionate self–responding, are redundant with neuroticism (especially its depression and anxiety facets) and do not evidence incremental validity in predicting life satisfaction. Using potentially problematic methods to examine the factor structure of the SCS (higher–order confirmatory factor analysis), they suggest a total self–compassion score should not be used and negative items should be dropped. In Study 1, we present a reanalysis of their data using what we argue are more theoretically appropriate methods (bifactor exploratory structural equation modelling) that support use of a global self–compassion factor (explaining 94% of item variance) over separate factors representing compassionate and reduced uncompassionate self–responding. While self–compassion evidenced a large correlation with neuroticism and depression and a small correlation with anxiety, it explained meaningful incremental validity in life satisfaction compared with neuroticism, depression, and anxiety. Findings were replicated in Study 2, which examined emotion regulation. Study 3 established the incremental validity of negative items with multiple well–being outcomes. We conclude that although self–compassion overlaps with neuroticism, the two constructs are distinct. © 2018 European Association of Personality Psychology
Mycobacterial skin and soft tissue infections : TB or not TB ?

Olanzapine, a second generation antipsychotic, has previously been associated with an increased risk of venous thromboembolism (VTE). In this mini-review we describe a case of a thirty-year-old schizophrenic patient who was diagnosed with a deep venous thrombosis (DVT) six months after starting olanzapine therapy, as well as seventeen other VTE cases in patients using olanzapine reported to the Netherlands Pharmacovigilance Centre Lareb. In 14 of these reports, patients had reported additional risk factors for VTE. We found disproportionate Reporting Odds Ratios (RORs) in the global database VigiBase for olanzapine and the reactions deep vein thrombosis (ROR of 1.38 with a 95% CI (Confidence Interval) of 1.22-1.57) and pulmonary embolism (ROR of 1.99 with a 95% CI of 1.81-2.19). The mechanism behind the association of olanzapine with VTE could be explained by two risk factors, substantial weight gain and lethargy, both common side effects of olanzapine. So far, a direct effect of olanzapine on platelet aggregation or coagulation has not been found. Schizophrenic patients are more likely to have diagnostic delay in the diagnosis of VTE, as symptoms such as lethargy and impaired pain perception result in diminished pain perception and pain expression, while they are at increased risk of developing VTE. Currently no validated risk score is available for detection of psychiatric patients who might benefit from pharmacologic VTE prophylaxis. In patients developing a VTE while being treated with olanzapine, discontinuation of olanzapine could be considered based on the individual risk profile, control of psychotic symptoms and antipsychotic treatment options.
A Compact QPSK Modulator with Low Amplitude and Phase Imbalance for Remote Sensing Applications

A new, compact and wide-band Quadrature Phase Shift Keying (QPSK) modulator is presented for remote sensing applications. The microstrip-based modulator employs quadrature hybrid coupler, Wilkinson divider, rat race coupler and GaAs MESFET switches. It is designed to be part of an X band remote sensing transmitter with a center frequency of 8.25GHz. The fabricated module demonstrates the lowest reported amplitude and phase imbalances (0.1dB and 0.4° respectively) around its center frequency. The modulation, tested up to 160 Mbps data rate, displays carrier suppression greater than 30 dB. With negligible DC power consumption and low insertion loss, it operates for a wide bandwidth of 3 GHz (7-10 GHz). The effect of amplitude and phase imbalance is investigated on the performance of the modulator. Finally, a transmitter employing this modulator exhibits an excellent overall Error Vector Magnitude (EVM) of around 8 % that is considerably low as compared to the typically obtained values for such transmitters.