Miracle-dz/UniFAR-FTUs huggingface dataset:
Diallel Crosses in Nicotiana tabacum 1

COMPARISONS of parent and F1 hybrid performance in tobacco are numerous in literature and a review of this early work was given by Ashton (1). The objective most previous studies has been to assess the amount of heterosis and to determine if it was sufficient to justify the use of F1 hybrids on a commercial scale. Even though tobacco is naturally self-fertilized, crossing can be accomplished with ease and seed yields are high. In some cases workers have advocated the use of F1 hybrids commercially, e.g., Bawolska et al. (2), however, most authors refer "fixing of heterosis" in later generations, e.g., Rave and Bolsunov (3). The resolution of the question of whether heterosis can be maintained only in the F1 generation, or whether transgressive segregates can be isolated in pure lines equal or superior to the F, depends upon the types of predominant gene action for each character in the population under study. Very little has been done to relate the amount of heterosis obtained in tobacco crosses with estimates of types or amount of genetic variability. As the first step in a program to obtain quantitative genetic information in fluecured tobacco and to relate this information to breeding methodology, the present experiment was planned with the following objectives: (1) to estimate the amount of heterosis and inbreeding depression in flue-cured tobacco crosses, (2) to test for differences between reciprocal F hybrids, (3) to obtain estimates of variances of general and specific combining ability, and (4) to measure the stability of general and specific effects with respect to environmental differences. The material used will form the foundation for extensive statistical genetic studies to determine more clearly the genetic mechanism governing the inheritance of a number of characters and their response to selection.
The Journal of Pain Lifespan Developmental Perspective on Chronic Pain Development : Pediatric Considerations Development of Nociception and Pain Fetuses

*Departments of Anesthesiology and Pain Medicine, Pediatrics, and Psychiatry, University of Washington School of Medicine, Seattle, Washington. ySeattle Children’s Hospital, Seattle, Washington. zDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, California. xStanford Children’s Health, Palo Alto, California. {Department of Medicine, Duke University Medical Center, Durham, North Carolina. kGRECC, Durham VA Medical Center, Durham, North Carolina. **VA Pittsburgh Geriatric Research, Education and Clinical Center, Pittsburgh, Pennsylvania. yyDepartments of Medicine, Psychiatry, and Anesthesiology, Clinical and Translational Science Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Microcirculation after Achilles tendon rupture correlates with functional and patient-reported outcome Running head : Blood flow may predict tendon healing potential

Introduction: Patients with acute Achilles tendon rupture (ATR) display an extended healing process with varying clinical outcome. Poor microcirculatory blood flow has been suggested to be a significant factor for the healing process. However, whether microcirculation may predict healing outcome has been mostly unknown. Therefore, we investigated if blood flow in the Achilles tendon may be associated with patientreported and functional outcomes after ATR. Methods: In vivo laser Doppler flowmetry was used to assess microvascular blood flow bilateral in the Achilles tendons, during post-occlusive reactive hyperemia, of nine patients with acute total ATR at two weeks post-operatively. At three months post-operatively, patient-reported outcome was assessed using Achilles tendon Total Rupture Score (ATRS). At one year a uniform outcome score, Achilles Combined Outcome Score (ACOS), was obtained by combining validated, independent, patientreported (ATRS) and functional outcome (heel-rise test) measures. Results: An improved combined patient-reported and functional outcome, ACOS, at one year was significantly correlated with higher maximum blood flow (r= 0.777, p= A cc ep te d A rt ic le This article is protected by copyright. All rights reserved. 0.040) in the injured limb. Furthermore, enhanced patient-reported outcome, ATRS, at three months, was associated with an elevated ratio of maximum to resting blood flow (r= 0.809, p= 0.015) in the uninjured limb. Conclusion: Blood flow in early tendon healing is associated with long-term patientreported and functional outcomes after ATR. The microcirculatory blood-flow of both the healing and contralateral Achilles tendon seems to determine the healing potential after injury.
Comparative study of movement patterns of Mastomys natalensis in irrigated rice and fallow fields in eastern Tanzania

A 2-year capture–mark–recapture study was conducted to estimate home ranges and weekly travel distance of Mastomys natalensis (Smith 1834) in an irrigated rice ecosystem and fallow fields. We found that adults have larger home ranges than subadults in fallow fields but not in rice fields, indicating that fallow fields are more suitable for breeding. Travel distances were larger in rice fields, especially in the transplanting stage, during which rice fields are flooded and provide less food, causing movements into neighbouring fallow fields that then temporarily experience higher population density. A decrease in travel distance was observed in rice fields during the maturity stage, which can be explained by higher food availability and a more suitable, nonflooded situation. Movement of M. natalensis in rice-fallow mosaic landscapes thus seems to be driven by food availability and flooding status of the rice fields, which can be attributed to land use practices. Resume Une etude de deux ans a ete realisee par capture-marquage-recapture pour estimer le domaine vital et la distance de deplacement hebdomadaire de Mastomys natalensis (Smith 1834) dans un ecosysteme de rizieres irriguees et de champs en jachere. Nous avons constate que les adultes avaient un domaine vital plus etendu que les subadultes dans les jacheres mais pas dans les rizieres, ce qui indique que les jacheres sont plus appropriees pour la reproduction. Les distances parcourues etaient plus grandes dans les rizieres, specialement au moment du repiquage, quand les rizieres sont inondees et procurent moins de nourriture, ce qui entraine des deplacements dans les jacheres proches qui connaissent temporairement une densite de population plus elevee. On observe une diminution des distances parcourues dans les rizieres a maturite, ce qui peut s'expliquer par la plus grande disponibilite de nourriture et une situation non inondee plus adaptee. Les deplacements de M. natalensis dans des paysages en mosaique de rizieres-jacheres semblent donc etre determines par la disponibilite en nourriture et par l’etat, inonde ou pas, des champs de riz, qui peuvent etre attribues aux pratiques d'utilisation des terres.
The character of seafloor ambient noise recorded offshore New Zealand: Results from the MOANA ocean bottom seismic experiment

We analyze the characteristics of ambient noise recorded on ocean‐bottom seismographs using data from the 2009–2010 MOANA (Marine Observations of Anisotropy Near Aotearoa) seismic experiment deployed west and east of South Island, New Zealand. Microseism and infragravity noise peaks are clear on data recorded on the vertical channel of the seismometer and on the pressure sensor. The noise levels in the infragravity band (<0.03 Hz) on the horizontal seismometer channels are too high to show the infragravity peak. There is a small difference (∼0.25 Hz versus ∼0.2 Hz) in microseism peak frequencies between the two sides of the South Island on all three seismic channels. Our results show clear depth dependence between the peak frequency of infragravity waves and the water depth. We find that the product of water depth and wave number at the peak frequency is a constant,koH = 1.5. This relationship can be used to determine the variation of phase and group velocity of infragravity waves with water depth, and the location of the infragravity peak and corresponding noise notch at any water depth. These estimates of spectral characteristics, particularly low noise bands, are useful for future OBS deployments.
sulfurreducens Production by Cytochrome Essential for Optimal Current-Type c an Outer-Surface , Octaheme Purification and Characterization of OmcZ

Published Ahead of Print 16 April 2010. 10.1128/AEM.00027-10. 2010, 76(12):3999. DOI: Appl. Environ. Microbiol. and Derek R. Lovley Kim, Tünde Mester, Mounir Izallalen, Carlos A. Salgueiro Kengo Inoue, Xinlei Qian, Leonor Morgado, Byoung-Chan Geobacter sulfurreducens Production by Cytochrome Essential for Optimal Current -Type c an Outer-Surface, Octaheme Purification and Characterization of OmcZ,
Determinants of productivity in Africa: The role of economic freedom

This paper examines the determinants of multifactor productivity in a cross-country study of 33 African countries. Among others, we specifically focus on the role of economic freedom, and its subcomponents, as defined by the Heritage Foundation/Wall Street Journal Economic Freedom Index (EFI). The empirical results show that the economic freedom index (and most of its components) has a positive and statistically significant impact on the productivity of African nations. The components of economic freedom that are critically important to enhancing productivity of African countries are: Business freedom, investment freedom, financial freedom, property rights freedom and freedom from corruption. We also investigate ‘bivariate granger-causality’ between economic freedom and total productivity. The results show that economic freedom granger-causes total factor productivity in most of these countries, but the other way around is not true.
Regime-Switching in Emerging Stock Market Returns

Many emerging markets have experienced significant changes in government policies and capital market reforms. These changes may lead to changes in their return-generating processes. Based on Markov-switching models, this paper investigates whether there is more than one regime in the return-generating processes of nine emerging markets and the specific characteristics of each regime. The results show very strong evidence of regime-switching behavior in emerging stock market returns. The two regimes through which emerging markets evolve are different whether one takes the domestic investors' perspective or that of foreign investors. For foreign investors, changes in volatility seem to be the main characteristic of emerging market regimes. The implications of these findings for the stability of emerging stock markets are discussed.
Some International Evidence on Output-Inflation Tradeoffs.

This paper reports the results of an empirical study of real output-inflation tradeoffs, based on annual time-series from eighteen countries over the years 1951-67. These data are examined from the point of view of the hypothesis that average real output levels are invariant under changes in the time pattern of the rate of inflation, or that there exists a "natural rate" of real output. That is, we are concerned with the questions (i) does the natural rate theory lead to expressions of the output-inflation relationship which perform satisfactorily in an econometric sense for all, or most, of the countries in the sample, (ii) what testable restrictions does the theory impose on this relationship, and (iii) are these restrictions consistent with recent experience? Since the term "'natural rate theory" refers to varied aggregation of models and verbal developments,' it may be helpful to sketch the key elements of the particular version used in this paper. The first essential presumption is that nominal output is determined on the aggregate demand side of the economy, with the division into real output and the price level largely dependent on the behavior of suppliers of labor and goods. The second is that the partial "rigidities" which dominate shortrun supply behavior result from suppliers' lack of information on some of the prices relevant to their decisions. The third presumption is that inferences on these relevant, unobserved prices are made optimally (or "rationally") in light of the stochastic character of the economy. As I have argued elsewhere (1972), theories developed along these lines will not place testable restrictions on the coefficients of estimated Phillips curves or other single equation expressions of the tradeoff. They will not, for example, imply that money wage changes are linked to price level changes with a unit coefficient, or that {"long-run"' (in the usual distributed lag sense) Phillips curves must be vertical. They will (as we shall see below) link supply parameters to parameters governing the stochastic nature of demand shifts. The fact that the implications of the natural rate theory come in this form suggests an attempt to test it using a sample, such as the one employed in this study, in which a wide variety of aggregate demand behavior is exhibited. In the following section, a simple aggregative model will be constructed using the elements sketched above. Results based on this model are reported in Section II, followed by a discussion and conclusions.
Computational Fluid Dynamics Modeling of Steam Condensation on Nuclear Containment Wall Surfaces Based on Semiempirical Generalized Correlations

In water-cooled nuclear power reactors, significant quantities of steam and hydrogen could be produced within the primary containment following the postulated design basis accidents (DBA) or beyond design basis accidents (BDBA). For accurate calculation of the temperature/pressure rise and hydrogen transport calculation in nuclear reactor containment due to such scenarios, wall condensation heat transfer coefficient (HTC) is used. In the present work, the adaptation of a commercial CFD code with the implementation of models for steam condensation on wall surfaces in presence of noncondensable gases is explained. Steam condensation has been modeled using the empirical average HTC, which was originally developed to be used for “lumped-parameter” (volume-averaged) modeling of steam condensation in the presence of noncondensable gases. The present paper suggests a generalized HTC based on curve fitting of most of the reported semiempirical condensation models, which are valid for specific wall conditions. The present methodology has been validated against limited reported experimental data from the COPAIN experimental facility. This is the first step towards the CFD-based generalized analysis procedure for condensation modeling applicable for containment wall surfaces that is being evolved further for specific wall surfaces within the multicompartment containment atmosphere.
David Reich multiplexed target capture Cost-effective , high-throughput DNA sequencing libraries for Material

Material Supplemental http://genome.cshlp. org/content/suppl/2012/01/20/gr.128124. 111.DC1. html References http://genome.cshlp. org/content/22/5/939.full. html#ref-list-1 This article cites 29 articles, 8 of which can be accessed free at: License Commons Creative . http://creativecommons.org/licenses/by-nc/3.0/ described at as a Creative Commons License (Attribution-NonCommercial 3.0 Unported License), ). After six months, it is available under http://genome.cshlp. org/site/misc/terms.xhtml for the first six months after the full-issue publication date (see This article is distributed exclusively by Cold Spring Harbor Laboratory Press
Establishing etiopathogenesis in Epstein-Barr virus associated malignancies using chromogenic in situ hybridization

Background: Epstein–Barr virus is a human herpes virus ubiquitously infecting 90% of world population and causing 1% of tumors worldwide. The objectives were to establish etiopathogenesis in the Epstein-Barr virus (EBV) associated malignancies reported in our laboratory using the gold standard test, i.e., chromogenic in situ hybridization (CISH) for Epstein-Barr virus - encoded RNA (EBER). Aims and Objectives: We performed CISH on 244 cases of associated malignancies in the year 2013–2016, the decision was taken after H and E diagnosis and immunohistochemistry confirmation. Observation and Results: In the period of 2013–2016, 253 cases were evaluated by CISH for EBER. The age range in our study was 5–88 years with the mean age of 41.8 years, a slight male predominance was noted with male: female ratio of 1.5:1. CISH in 61 Classical Hodgkin lymphoma cases of 90cases were positive Conclusion: EBER ISH is the single best histochemical assay for defining EBV - related neoplasia. It is likely that emerging technologies such as gene expression profiling and proteomics will identify patterns of viral and human gene expression correlating with diagnosis, prognosis, and outcome in response to therapy.
Mixtures of charged-neutral superfluids

MIXTURES OF CHARGED-NEUTRAL SUPERFLUIDS Fatmanur Ünal Ph.D. in Physics Advisor: Mehmet Özgür Oktel December 2016 Motivated by the developments of artificial magnetic fields (AMFs) enabling coupling to the neutral particles of ultracold quantum gases, we have theoretically studied charged-neutral mixtures in various settings. The techniques that have been used to manufacture these AMFs are highly sensitive to the internal degrees of freedom of the atoms, resulting in unequal coupling to the components of a mixture. We demonstrate the possible consequences of this unequal coupling by considering two different systems. First, we examine an impurity problem in a fermion background under an AMF coupling selectively to the impurity in a ring trap. We calculate the response of the system exactly by using Bethe Ansatz and argue that the AMF can be employed as a probe to analyze polaron formation. Secondly, we explore Bardeen-Cooper-Schrieffer theory of superconductivity in the presence of a charge imbalance under an AMF. We analytically calculate the gap equation for any degree of asymmetry between the Landau level spectra of up and down spin particles, and show that the system displays reentrant superconductivity both in magnetic field and temperature. Apart from mixtures, we also investigate the non-equilibrium Hall response of a topological system. The strength of an AMF applied on a optical lattice can be suddenly changed without creating Eddy currents, allowing us to quench the system across a topological phase boundary. We report a fractional Hall response for the resulting non-equilibrium system and discuss possible implementations for cold atom experiments.
MacrophagesTLR2-Dependent ERK Activation in Predominant IL-10 Production via Strains into Lactobacillus Certain Predominant IL-12 Production Induced by Bacterial Teichoic Acids Reverse

The cytokine response of macrophages to probiotic lactobacilli varies between strains, and the balance of IL-10/IL-12 production is crucial for determination of the direction of the immune response. To clarify the mechanism whereby Lactobacillus strains differentially induce production of IL-10 and IL-12, we examined the potential relationship between cytokine production and MAPK activation. In mouse peritoneal macrophages, Lactobacillus plantarum potently induced IL-10 but weakly induced IL-12 production, whereas L. casei potently induced IL-12 but weakly induced IL-10 production. Kinetic analysis of the activation of ERK, p38, and JNK showed that L. plantarum induced a more rapid and intense activation of MAPKs, especially of ERK, than L. casei . A selective blockade of ERK activation induced by L. plantarum resulted in a decrease in IL-10 production and a simultaneous increase in IL-12 production. Interestingly, when macrophages were stimulated with a combination of L. plantarum and L. casei , IL-10 production was induced synergistically. We identiﬁed cell wall teichoic acid and lipoteichoic acid as key factors for triggering the synergistic induction of IL-10 production, although these teichoic acids alone only weakly induced IL-10 production. The effect of these teichoic acids on IL-10 production was mediated by TLR2-dependent ERK activation. Our data demonstrate that activation of the ERK pathway is critical for determination of the balance of the IL-10/IL-12 response of macrophages to lactobacilli and that predominant IL-12 production induced by certain lactobacilli such as L. casei can be converted into predominant IL-10 production when stimulated in the presence of teichoic acids. The Journal of Immunology , mechanism of IL-10 and IL-12 production induced by lactobacilli by studying MAPK activation in mouse peritoneal macrophages following recognition of three strains L. plantarum , potently casei johnsonii , which weakly induces the production both IL-10 and IL-12. Additionally, we investigated the bacterial cell components and their that are involved in MAPK activation. We report that activation by plays a key role in determination of the balance of IL-10/IL-12 production by macrophages in response to lactobacilli.
Stability Analysis of Elite Chickpea Genotypes Tested under Diverse Environments

Twelve elite chickpea genotypes along with two check varieties were grown at four diverse locations in Punjab province to check their stability. The analysis of variance for seed yield at individual locations showed significant to highly significant differences between genotypes. Pooled analysis of variance over locations displayed highly significant differences between genotypes, locations and genotype x location interaction. Among 14 genotypes, the maximum mean seed yield over the locations was produced by the CC119/00 (1.229 t ha{-1}) and the highest mean seed yield producing location was NIAB (1.412 t ha{-1}). The cluster analysis effectively grouped the locations and genotypes into three clusters each viz. low, medium and high yielding ones. G x E interaction was of crossover in nature. Partitioning of total variance revealed significant differences among environments and genotypes for grain yield demonstrating the presence of considerable variations among genotypes as well as diversity of environments at various locations. The analysis of stability based on mean grain yield, regression coefficient and deviation from regression revealed that the genotypes; CC119/00, CC117/00 (Colchicine mutants), CM256/99, CH38/00 and K-70022 were most stable and adapted to the diverse environmental conditions of Punjab. Previously colchicine was only known to cause chromosome doubling but now it is also known to induce mutations. This is the first report of the systematic work on the mutants induced through colchicine treatments and demonstrated their yield superiority and stability over the locations. These genotypes are recommended for commercial cultivation and can also be effectively utilized in the recombination breeding programs to enhance genetic variability in kabuli chickpea.
Long-Lived Larvae of the Gastropod Aplysia juliana: Do They Disperse and Metamorphose or Just Slowly Fade Away

The planktonic larvae of the opisthobranch Aplysia juliana stop growing about 30 d after release from the egg niass. Both tissue and shell mass remain at a plateau in excess of 200 d. During this pel-~od larvae swim, feed dnd renlaln conlpetent to metamorphose. Mortality of larvae in long-term cultures appears to be due to envlronn~ental factors rather than senescence. The potential duration of larval life suggests that these larvae are capable of long-d~stance dispersal by major ocean currents.