Miracle-dz/UniFAR-FTUs huggingface dataset:
Efforts to induce estrus in the bitch, using pituitary gonadotropins.

: Induction of fertile estrus in 14 anestrous bitches was attempted, using pituitary gonadotropins given by intramuscular injection in 3 treatment regimens: as a single dose of 10-mg follicle stimulating hormone (FSH; 5 bitches), as multiple doses of FSH (1, 2, 4, 8, 16 mg) given to 4 bitches on days 1 and 2, 3 and 4, 5 and 6, 7 and 8, and 9 and 10, and as multiple doses of combined FSH and luteinizing hormone (LH; 1:1, 1:1, 2:1, 4:1, 8:2.5, 16:5 mg) given to 5 bitches on days 1, 3, 5, 7, 9, and 11, respectively. Four bitches were injected with equivalent volume of isotonic NaCl solution (saline). Treatments were evaluated by observation of sexual behavior in presence of a male, microscopic changes in exfoliated vaginal epithelium, plasma concentrations of estradiol-17 beta and progesterone, and qualitative and quantitative, gross and microscopic changes in the ovaries and uterus. Four of the 14 treated bitches came into estrus and mated (one became pregnant), two after single, and two after multiple doses of FSH. In each of the four, vaginal cornification, plasma estradiol and progesterone patterns, and ovarian and uterine changes were comparable with those seen in the one saline-treated bitch with a spontaneous estrous cycle and pregnancy. Three treated bitches manifested proestrous behavior (2 after a single injection and 1 after multiple injections of FSH) but had no measurable response in the vaginal epithelium, endocrine patterns, or appearance of ovaries and uterus. Seven gonadotropin-treated bitches and 3 saline-treated bitches did not respond in any way. (ABSTRACT TRUNCATED AT 250 WORDS)
THE ROLE OF NOSTALGIA PRONENESS IN THE EFFECT OF BRAND IMAGE, CORPORATE IMAGE, BRAND TRUST AND CONSUMER INVOLVEMENT ON EMOTIONAL ATTACHMENT: GLOBAL VS. LOCAL BRAND

Nostalji, “bireylerin gecmise duyduklari arzu veya gecmis gunlerde yasananlara ve sahip olunanlara karsi hissedilen hoslanma” olarak tanimlanmaktadir (Holbrook, 1993, p. 245). Son yillarda pazarlama alaninda, nostalji, tuketicilerde olumlu duygular uyandirmak amaciyla yaygin olarak kullanilmaktadir (Holak et al., 2007). Bu baglamda, bu calismanin amaci Marka Imaji, Kurumsal Imaj, Marka Guveni ve Tuketici Ilgilenimi’nin Duygusal Baglilik uzerindeki etkisinde Nostalji’nin rolunu incelemektir. Kavramsal model farkli nostalji egilimi duzeylerine (yuksek/dusuk) sahip tuketiciler acisindan test edilmistir. Ayrica, bir kuresel ve bir yerel marka icin model karsilastirilmistir. Kolayda ornekleme ve yuzyuze anket yontemi ile Istanbul ilinde 643 anket toplanmistir. Arastirma hipotezlerini test etmek amaciyla Regresyon Analizi kullanilmistir. Arastirma bulgularina gore, her iki marka ve her iki nostalji egilimi duzeyindeki cevaplayici gruplari icin tum bagimsiz degiskenler duygusal baglilik bagimli degiskeni uzerinde istatistiksel olarak anlamli etki gostermektedir. Ancak, gerek markalar gerek nostalji duzeylerine gore etki dereceleri ve siralamalarinda farkliliklar tespit edilmistir.
Acquired inguinal hernia in the horse: a review of 27 cases.

: Twenty-seven cases of acquired inguinal hernia in the horse were reviewed. The history, clinical signs, treatment, and complications were summarized. Mortality was 25.9%. Only 13 or the 27 cases were diagnosed prior to admission. With early diagnosis and treatment, mortality should approach zero. In 24 of these cases, the hernia was strangulated. In each case, the signs were colic, a firm slightly enlarged testicle in the scrotum, and small intestine displacement through the inguinal ring, as determined via rectal palpation. In was concluded that palpation of the scrotum and inguinal rings should be performed on every stallion with colic. The importance of early diagnosis in decreasing mortality was illustrated by the comparison of nonsurvivors to survivors.
Public opinion on UK milk marketing and dairy cow welfare

Interview questionnaires were administered to the general public in central Scotland and northern England during summer 2007 to investigate consumer awareness of UK dairy production methods, welfare issues and recognition of ‘quality assurance’ product logos. Fifty percent of respondents gave UK dairy animal welfare a positive rating. Recognition of individual quality assurance logos was poor and 75% of respondents stated that they did not intentionally seek to buy products with any of the logos. Respondents’ perceptions of good dairy welfare included: appropriate feeding, good stockmanship, plenty of space, freedom to roam/free range and environmental cleanliness. Half of respondents felt they were poorly informed about food production and the majority of respondents (68%) would like more information on food production. Respondents believed that information on animal welfare provided by veterinarians and farmers would be reliable. Most respondents (93%) said they would pay more for good dairy welfare. The findings show that the general public are interested in animal welfare but could be better informed on dairy animal production and welfare. Veterinarians and farmers may have a potentially important role in providing this information with increasing demand for higher welfare provenance products potentially helping to improve animal welfare.
Yedinci Sınıf Öğrencilerinin STEM Etkinlikleri Hakkındaki Görüşleri: Karışımların Ayrıştırılması Örneği

STEM egitim yaklasimi, STEM disiplinlerindeki gercek yasam problemlerine odaklanmaktadir. Muhendislik tasarim sureci STEM egitim yaklasiminda uygulanabilecek yontemlerden birisidir. Bu calismanin amaci “Karisimlarin Ayristirilmasi” konusunda muhendislik tasarim sureci kullanilarak gelistirilen STEM etkinligine iliskin ogrenci goruslerini belirlemektir. Arastirma nitel arastirma yaklasimlarindan durum calismasina gore yurutulmustur. Calismanin orneklemini, 2016-2017 Egitim-Ogretim yilinda Dogu Karadeniz Bolgesi’nin ic kesiminde bulunan bir koy okulunun 7. sinifinda ogrenim goren toplam 13 ogrenci (5 erkek ve 8 kiz) olusturmaktadir. Veri toplama araci olarak, yari yapilandirilmis gorusme formu kullanilmistir. Etkinlik sonunda ogrencilerle yapilan yari yapilandirilmis gorusmelerden elde edilen veriler icerik analizi ile analiz edilmistir. Arastirmada ogrencilerin tasarimlarini yaparken birtakim zorluklar yasadiklari ortaya cikmistir. Bununla birlikte etkinliklerin ogrencilere bircok alanda olumlu ozellikler kazandirdigi, etkinlikler sirasinda ogrencilerin cok eglendikleri ve derse karsi ilgilerinin arttigi sonucuna ulasilmistir. Ayrica, gorusmelerden elde edilen sonuclar, STEM etkinliginin ogrencilerde; is birligi, elestirel dusunebilme, problem cozebilme, yaraticilik, ozguven gibi 21.yuzyil becerilerine katki sagladigini ortaya koymustur.
Exploring Task-agnostic, ShapeNet-based Object Recognition for Mobile Robots

This position paper presents an attempt to improve the scalability of existing object recognition methods, which largely rely on supervision and imply a huge availability of manually-labelled data points. Moreover, in the context of mobile robotics, data sets and experimental settings are often handcrafted based on the specific task the object recognition is aimed at, e.g. object grasping. In this work, we argue instead that publicly available open data such as ShapeNet can be used for object classification first, and then to link objects to their related concepts, leading to task-agnostic knowledge acquisition practices. To this aim, we evaluated five pipelines for object recognition, where target classes were all entities collected from ShapeNet and matching was based on: (i) shape-only features, (ii) RGB histogram comparison, (iii) a combination of shape and colour matching, (iv) image feature descriptors, and (v) inexact, normalised cross-correlation, resembling the Deep, Siamese-like NN architecture of Submariam et al. (2016). We discussed the relative impact of shape-derived and colour-derived features, as well as suitability of all tested solutions for future application to real-life use cases.
p53-associated differential response to platinumgemcitabine and platinum-paclitaxel in advanced nonsmall cell lung cancer

Abstract Background: Platinum-paclitaxel and platinum-gemcitabine are commonly used first-line chemotherapies for advanced non-small-cell lung cancer (NSCLC). Currently, there is no established biomarker predicting the treatment outcomes of these two regimens. Previous studies have suggested that p53 expression might determine the response to platinum compounds and gemcitabine, but not paclitaxel. We hypothesized that p53 overexpression would predict a worse response to platinum-gemcitabine than to platinum-paclitaxel in patients with advanced NCSLC. Objective: To investigate whether tumor p53 expression would be able to predict the treatment outcome of these two chemotherapy regimens in advanced NSCLC patients. Methods: We identified patients with advanced NSCLC who had been treated with either platinum-gemcitabine or platinum-paclitaxel as first-line chemotherapy at King Chulalongkorn Memorial Hospital. We obtained the corresponding archived tissue samples and performed immunohistochemical staining to determine the p53 expression in tumor tissues. We then compared the response rates and time to progression (TTP) between two regimens and p53 expression statuses. Results: Of the 76 advanced NSCLC patients, we identified 40 (52.6%) patients with p53 overexpression, in which we showed better treatment outcomes with platinum-paclitaxel than with platinum-gemcitabine: the response rates were 42.1% vs 14.3% (p = 0.053) and TTPs were 5.3 [95%CI, 4.3-6.3] months vs 3.3 [95%CI, 1.3-5.2] months (p = 0.067). In the platinum-gemcitabine group, the response rate and TTP were better in normal expression of p53 subgroup compared to p53-overexpression subgroup (response rate 47.4% vs 14.3%, p = 0.026 and TTP 5.0 [95%CI, 4.4-5.5] months vs 3.3 [95%CI, 1.3-5.2] months, p = 0.062). These differences were not found in the platinum-paclitaxel group. Conclusion: Our findings suggest that p53 expression is a potential predictive marker for the response to platinum-gemcitabine in advanced NSCLC. Consequently, platinum-paclitaxel would be favored over platinumgemcitabine in patients with p53 overexpression.
A COMPARISON OF MATERNITY CARE MODELS AND THEIR RELATIONSHIP TO ADVERSE FETAL AND NEONATAL OUTCOMES: A RETROSPECTIVE COHORT STUDY BASED IN NEW ZEALAND.

i ACKNOWLEDGEMENTS iv LIST OF TABLES viii LIST OF FIGURES ix LIST OF ABBREVIATIONS x CHAPTER ONE: INTRODUCTION 1 CHAPTER TWO: BACKGROUND 5 2.0 A History of New Zealand’s Maternity System 1900-1990 5 2.1 The Path to Change 12 2.2 The New Maternity System 18 2.3 The Maternity Debate 22 2.4 The Response of the Government 28 CHAPTER THREE: LITERATURE REVIEW 37 3.0 Maternity Care Safety Outcomes within New Zealand 37 3.1 New Zealand Maternal Mortality Ratios, Perinatal Mortality Rates and Caesarean Section Rates: 1980-2011 40 3.2 International Comparison of Maternity System Outcome Measures 46 3.3 Literature Review: The Safety of Midwife-Led Care 50 3.30 New Zealand Based Research 50 3.31 International Research 52 3.32 The Dutch Study 63 3.4 Conclusion 66
Finding Answers Online in Sickness and in Health

Recent research from the Pew Internet & American Life Project shows that, as more and more Americans come online, so too do more Americans rely on the internet for important health information. In a March 2005 survey, 12% of online adults –representative of 17 million people--said the internet played a crucial or important role as they helped another person cope with a major illness. When the same question was asked in a January 2002 survey, nearly the same proportion (10%) said the net played a major role in such circumstances, but that represented only 11 million people. In addition, the March 2005 survey found the number of those who said the internet played a crucial or important role as they themselves coped with a major illness reached 7 million while a December 2005 survey found that one in five (20%) online Americans said the internet has greatly improved the way they get information about health care.
Osteoporosis and fracture prevention: costs and effects modeled on the Rotterdam study

textabstractOsteoporosis is defined, by consensus, as a systemic skeletal disease. characterized by low bone mass and microarchitectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to fracture,' It is well known that there is an important age-related decrease in bone mass and bone strength as witnessed by the exponential increase of hip fractures with age.2 Osteoporosis is primarily described in postmenopausal women but men arc not free from it. and a quarter of the hip fractures occurs in men.3 Osteoporosis and its direct consequences, fractures, are major concerns for public health since they arc associated with increased death rates and with substantial disability. :Moreover, they represent an important cost for the public health budget. 'TIle European Commission estimated in a recent report the cost of osteoporosis in the countries of the European Union at € 3.5 billion annually for hospital health care alone,4 and an American study estimated the total health care expenditure attributable to osteoporotic fractures in the United States at USS 13.8 billion (€ 12.4 billion) in 1995. ' Without intervention, the improved life expectancy and the demographic evolution will cause the number of hip fractures worldwide to increase from around 1.7 million in 1990 to over 6 million in 2050.6 Therefore, it can be expected that medical expenditure will also increase in the coming decades. Osteoporosis, defined as a reduction in bone mass below a specified threshold, has been shown to be a major determinant of fracture risk.7 Bone mass can be measured with sufficient accuracy and precision and it is currently the best available indicator of fracture risk, other than age and gender. There is, however, a considerable overlap of bone density values between people who develop fractures and people who do not.2 The central goal of this thesis is to study the cost of osteoporosis and fractures in the Netherlands and to develop mathematical models for estimating fracture risk based on Dutch epidemiological data. These models are then used in simulations to analyze the effects of potential preventive measures against osteoporotic fractures. 'The most disabling of these is the hip fracture, but also wrist fractures and fractures of the vertebrae are considered as osteoporotic fractures.8 Also from a cost perspective the importance of hip fractures appears to be overwhelming, and therefore the models focus is on hip fractures.
The Effectiveness of A Teen Pregnancy Prevention Program That Offer Special Benefits For Pregnant and Parenting Teens: A Qualitative Study

iii Dedication v Acknowledgements vi TABLE OF CONTENTS vii LIST OF TABLES x CHAPTER ONE: INTRODUCTION 1 Background 1 Situation to Self 7 Problem Statement 8 Purpose Statement 8 Significance of the Study 9 Research Questions 10 Research Plan 11 Delimitations 14 CHAPTER TWO: LITERATURE REVIEW 15 Introduction 15 Theoretical Framework 16 Teen Sexual Practice and Pregnancy: Contributing Factors 21 Teenage Pregnancy Prevention Program Examples 48 God’s Views on Sex and Premarital Sexual Intercourse 55 CHAPTER 3: METHODOLOGY 6
Determinants and Pathways of Progression to Level 2 Qualifications: Evidence from the NCDS and BHPS

The commitment of the government to improving the education of the workforce has been emphasized both in the Five Year Strategy for Children and Learners of the Department for Education and Skills (DfES, 2004) - now Department for Children Schools and Families (DCSF) - and in the recently published Leitch Review, which calls for the UK to be a “world leader in skills”. Leitch also called for over 90 per cent of adults qualified to at least Level 2, an increase from 69 per cent in 2005, with a commitment to go further and achieve 95 per cent as soon as possible. However, our understanding of the characteristics and motivations of individuals who participate in level 2 courses is limited. While their demographic features are well known, few studies have used longitudinal data to look at the life histories of participants and thus our understanding of what may influence or predict their participation in learning is limited. This report aims to address this issue, describing the characteristics of people who return to learning to take level 2 qualifications and their pathways to progression. The research draws on two nationally representative longitudinal studies, the National Child Development Survey (NCDS) and the British Household Panel Survey (BHPS).
X-linked Bulbospinal Neuronopathy

Objective: To characterize the earliest symptoms of Xlinked bulbospinal neuronopathy (Kennedy disease [KD]) during the course of the disease, including a definition of the age of onset. Methods: We describe the earliest symptoms, signs on clinical investigation, electrophysiological and muscle biopsy specimen findings, and creatine kinase levels in 34 patients with KD. Correlations were made among the CAGrepeat length and clinical symptoms, age at onset, and the presence of electrophysiological and laboratory findings. Results: Our findings indicate that the age at onset of KD is in adolescence which is earlier than previously thought. Most frequently early symptoms are gynecomastia, muscle pain, and premature muscular exhaustion. Weakness is not a typical initial symptom and is frequently found in distal limbs if present early. We found a correlation between the of number of CAG repeats and the age at onset of weakness but not to the age at onset of KD. Furthermore, no correlations were found between the occurrence of gynecomastia, tremor, increased creatine kinase levels, and additional myopathic changes in muscle biopsy specimens. Conclusions: Our data show that KD is a multisystem disorder with onset in adolescence. Because of the heterogeneity of clinical presentation and no correlation between the number of CAG repeats and most of the clinical hallmarks of KD, we suggest that other environmental or genetic factors contribute to the manifestation of specific organ systems in KD. Arch Neurol. 2002;59:1921-1926
Advances in Financial Machine Learning: Numerai's Tournament (seminar slides)

Machine learning (ML) is changing virtually every aspect of our lives. Today ML algorithms accomplish tasks that until recently only expert humans could perform. As it relates to finance, this is the most exciting time to adopt a disruptive technology that will transform how everyone invests for generations. Readers will learn how to structure Big data in a way that is amenable to ML algorithms; how to conduct research with ML algorithms on that data; how to use supercomputing methods; how to backtest your discoveries while avoiding false positives. The book addresses real-life problems faced by practitioners on a daily basis, and explains scientifically sound solutions using math, supported by code and examples. Readers become active users who can test the proposed solutions in their particular setting. Written by a recognized expert and portfolio manager, this book will equip investment professionals with the groundbreaking tools needed to succeed in modern finance.
An investigation into the role of platelet-monocyte interaction and inflammation in coronary artery disease

Introduction: - Platelet monocyte complex (PMC) formation has been widely reported as a marker of platelet activation in vascular disease states and several studies have shown heightened systemic expression of PMC in stable and acute coronary disease. However, the relationship between intracoronary platelet and monocyte activation status and local intracoronary inflammation in acute coronary syndrome (ACS) remains unclear. Method:- Fifteen ST elevation myocardial infarction (STEMI), 8 non ST elevation myocardial infarction (NSTEMI) and 7 stable angina patients were recruited. PMC, P selectin positive PMC (activated platelet within the complex), tissue factor (TF) positive PMC (activated monocyte within the complex) were estimated with flow cytometry from blood samples aspirated from the coronary artery (distal to the lesion), aorta and right atrium . Plasma CRP, SAA, TNF –alpha and IL-6 were also measured. Results:- In ACS patients no significant transculprit lesion gradient of PMC expression was observed but significant gradients were found with P-selectin positive PMC (p= 0.01) and TF positive PMC expression (p=0.04). Overall median P- selectin positive PMC expression in ACS patients was significantly higher compared to stable angina (p= 0.006). Intracoronary P-selectin positive PMC was also found to be higher in the ACS group compared to stable group (p=0.003). Overall median CRP (p= 0.001), SAA (p=0.0007) and IL-6 (p= 0.03) levels were significantly higher in ACS. In STEMI intracoronary PMC correlated positively with intracoronary TNF-alpha (r= 0.68, p= 0.03). Positive correlation was also observed between intracoronary TF positive PMC (% monocyte) with TNF-alpha and IL-6 (r=0.66, p=0.05 & r=0.71, p= 0.05 respectively). Conclusion:- The work outlined in this thesis has demonstrated the importance of platelet and monocyte activation status of the PMC as a determinant of intracoronary inflammation. Beyond a local intracoronary role, PMC may contribute to systemic inflammation through P-selectin expression and local intracoronary inflammation through increased P-selectin and tissue factor expression.
Modalities of testing Helicobacter pylori in patients with nonmalignant bile duct diseases

AIM: This paper describes the procedure of detection ofHelicobacter pylori ( H. pylori) in bile specimens in patientssuffering from benign diseases of biliary ducts (lithiasiswith/without nonspecific cholangitis). METHODS: The group of 72 patients entering the studyconsisted of 32 male and 40 female (45 % and 55 %,respectively). Bile was obtained during ERCP in 68 patients,and during cholecystectomy in 4 patients. A fast urease test(FUT) to determine the existence of H. pylori in gastricmucosa was carried out for all the patients during theendoscopic examination. The existence of genetic materialof H. pylori was determined by detection of ure A gene bythe method of nested PCR. The results of this reaction wereshown by electrophoresis on l0 g@ L-1 agarose gel in a bandof 256 bp.RESULTS: The majority of the patients included in our studyhad biliary lithiasis without signs of cholangitis (48 patients,67 %), whereas other patients were complicated bycholangitis (17 patients, 24 %). Seven patients (9 %) hadnormal ERCP, forming thus the control group. In the groupof patients with lithiasis 26 patients (54.2 %) had positivePCR of H. pylori in bile and among the patients withassociated cholangitis positive PCR was detected in 9patients (52.9 % ). Among the seven patients with nornalERCP only one (14 %) had positive PCR of H. pylori. Ahigh percentage of H. pylori infection of gastric mucosawas observed (57 patients, 79 % ) : It was also observed thatits slightly higher positivity was in the patients with distinctbile pathology: 81% FUT positive patients in the group withcholedocholithiasis alone and 76 % in the group withcholedocholithiasis associated with cholangitis. Seventy-onepercent of the patients with regular findings had positive FUT.CONCLUSION: The prevalence of H. pylori infection both inbile and in gastric mucosa in patients with benign diseasesof biliary ducts does not show a statistically significantdifference in relation to the prevalence of the same with thepatients with normal ERCP. The existence of H. pylo