Miracle-dz/UniFAR-FTUs huggingface dataset:
Seizure clusters: characteristics and treatment.

PURPOSE OF REVIEW Many patients with epilepsy experience 'clusters' or flurries of seizures, also termed acute repetitive seizures (ARS). Seizure clustering has a significant impact on health and quality of life. This review summarizes recent advances in the definition and neurophysiologic understanding of clustering, the epidemiology and risk factors for clustering and both inpatient and outpatient clinical implications. New treatments for seizure clustering/ARS are perhaps the area of greatest recent progress. RECENT FINDINGS Efforts have focused on creating a uniform definition of a seizure cluster. In neurophysiologic studies of refractory epilepsy, seizures within a cluster appear to be self-triggering. Clinical progress has been achieved towards a more precise prevalence of clustering, and consensus guidelines for epilepsy monitoring unit safety. The greatest recent advances are in the study of nonintravenous route of benzodiazepines as rescue medications for seizure clusters/ARS. Rectal benzodiazepines have been very effective but barriers to use exist. New data on buccal, intramuscular and intranasal preparations are anticipated to lead to a greater number of approved treatments. Progesterone may be effective for women who experience catamenial clusters. SUMMARY Seizure clustering is common, particularly in the setting of medically refractory epilepsy. Clustering worsens health and quality of life, and the field requires greater focus on clarifying of definition and clinical implications. Progress towards the development of nonintravenous routes of benzodiazepines has the potential to improve care in this area.
Topography of orientation centre connections in the primary visual cortex of the cat

The functional topography of lateral connections to orientation-centre zones was studied by optical imaging of intrinsic signals in combination with tracer injections (fluorescent beads and biocytin) and electrophysiological recordings. Three-dimensional reconstruction of anterogradely labelled axon terminals and retrogradely labelled somata revealed a uniform distribution across all orientations in a non-patchy manner. The overall lateral extent of the labelling was 3–4 mm in layer 3, that is about half of the extent observed for orientation domain connections in the same layer. These bulk injection data are in contrast with the reportedly sharp orientation tuning of neurons of centre zones and suggest that orientation specificity here does not require highly specific connections. Nonetheless, another plausible scenario is that orientation centre connections are orientation specific but their specificity present at the single cell level cannot be revealed by bulk labelling due to their large spatial overlap.
Capacitive Micromachined Ultrasonic Transducers: Theory and Technology

Capacitive micromachined ultrasonic transducers ~CMUTs! , introduced about a decade ago, have been shown to be a good alternative to conventional piezoelectric transducers in various aspects, such as sensitivity, transduction efficiency, and bandwidth. In this paper, we discuss the principles of capacitive transducer operation that underlie these aspects. Many of the key features of capacitive ultrasonic transducers are enabled with micromachining technology. Micromachining allows us to miniaturize device dimensions and produce capacitive transducers that perform comparably to their piezoelectric counterparts. The fabrication process is described briefly, and the performance of the CMUT transducers is evaluated by demonstrating characterization results. It is shown that the transduction efficiency as defined by the electromechanical coupling coefficient can be close to unity with proper device design and operating voltage. It is also shown that CMUTs provide large bandwidth ~123% fractional bandwidth! in immersion applications which translate into high temporal and axial resolution. Finally, the feasibility of using CMUTs is demonstrated by showing imaging examples in air and in immersion.
Board meeting frequency and financial performance: A case of listed firms in Vietnam

This study investigates the effect of board meeting frequency on the financial performance of listed firms in a fiscal year. We use 94 firms listed on Ho Chi Minh Stock Exchange from 2013 to 2015. Financial performance is measured as returns on asset, equity and sales. Results show that board meeting frequency exerts a negative effect on the financial performance of the sample firms. High board meeting frequency equates to low returns on asset, equity and sales. Overall, the quality of board meetings is an important factor that contributes to financial performance.
A 1.35 GS/s, 10 b, 175 mW Time-Interleaved AD Converter in 0.13 µm CMOS

A time-interleaved ADC is presented with 16 channels, each consisting of a track-and-hold (T&H) and two successive approximation (SA) ADCs in a pipeline configuration to combine a high sample rate with good power efficiency. The single-sided overrange architecture achieves a 25% higher power efficiency of the SA-ADC compared with the conventional overrange architecture, and look-ahead logic is used to minimize logic delay in the SA-ADC. For the T&H, three techniques are presented enabling a high bandwidth and linearity and good timing alignment. Single channel performance of the ADC is 6.9 ENOB at an input frequency of 4 GHz. Multichannel performance is 7.7 ENOB at 1.35 GS/s with an ERBW of 1 GHz. The FoM of the complete ADC including T&H is 0.6 pJ per conversion step. An improved version is presented as well and achieves an SNDR of 8.6 ENOB for low sample rates, and, with increased supply voltage, it reaches a sample rate of 1.8 GS/s with 7.9 ENOB at low input frequencies and an ERBW of 1 GHz. At fin = 3.6 GHz, the SNDR is still 6.5 ENOB, and total timing error including jitter is 0.4 ps rms.
Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon

The selective CB1 receptor antagonist rimonabant (SR141716) was shown to perform a number of biological effects in several pathological conditions. Emerging findings demonstrate that rimonabant exerts antitumor action in thyroid tumors and breast cancer cells. In our study, human colorectal cancer cells (DLD‐1, CaCo‐2 and SW620) were treated with rimonabant and analyzed for markers of cell proliferation, cell viability and cell cycle progression. Rimonabant significantly reduced cell growth and induced cell death. In addition, rimonabant was able to alter cell cycle distribution in all the cell lines tested. Particularly, rimonabant produced a G2/M cell cycle arrest in DLD‐1 cells without inducing apoptosis or necrosis. The G2/M phase arrest was characterized by a parallel enhancement of the number of mitoses associated to elevated DNA double strand breaks and chromosome misjoining events, hallmarks of mitotic catastrophe. Protein expression analyses of Cyclin B1, PARP‐1, Aurora B and phosphorylated p38/MAPK and Chk1 demonstrated that rimonabant‐induced mitotic catastrophe is mediated by interfering with the spindle assembly checkpoint and the DNA damage checkpoint. Moreover, in the mouse model of azoxymethane‐induced colon carcinogenesis, rimonabant significantly decreased aberrant crypt foci (ACF) formation, which precedes colorectal cancer. Our findings suggest that rimonabant is able to inhibit colorectal cancer cell growth at different stages of colon cancer pathogenesis inducing mitotic catastrophe in vitro. © 2009 UICC.
Determinants of Shari’ah governance disclosure in financial institutions

Purpose This paper aims to investigate factors influencing Shari’ah governance disclosure (SGD) in financial institutions. Design/methodology/approach Using content analysis approach, 46 annual reports published in 2015 by banks and insurance companies were investigated based on a self-constructed disclosure index. Findings The results show that the average level of voluntary disclosure of Shari’ah governance in Saudi financial institutions is 11.7 per cent, which is lower than expectations Moreover, regression analysis shows that industry type, ownership structure and board composition significantly determine the extent of voluntary disclosure of Shari’ah governance. Local financial institutions which are owned by non-governmental agencies are more likely to disclose voluntarily their Shari’ah governance, in particular from the banking industry. Research limitations/implications It also bridges the gap between theory and practice and can be used to practice economic and commercial impact in teaching to influence public policy in research contributing to the body of knowledge and especially for the insurance sector and government. Social implications It provides guidance to the ethical investors and supports them in the decision-making process. Originality/value This research extends the investigation of SGD into insurance sector in a country that has a general policy about adhering to Islamic principles. Financial institutions might go beyond the country affirmations to legitimate their identity in response to the society critiques about the issue. Accordingly, internal attributes and strategies of financial institutions may play a significant role in distinguishing its compliance with Islamic principles to respond to the society critiques about financial transactions.
Satisfaction and Service Quality of Using High-Speed 4G Wireless Broadband in University Campus

This paper aims to examine customers’ satisfaction with the product service quality rendered by high-speed 4G wireless broadband (YES! ) and YES! Campus Store. 161 of 300 students were engaged from numerous faculties at Universiti Teknologi MARA, Shah Alam, Selangor, Malaysia. Based on a survey, this study suggested that tangibility, reliability, responsiveness, assurance, and empathy produce negative results. It shows that the service rendered by YES! does not meet the expectation of customers’ satisfaction. This paper draws attention to the importance of having high-speed 4G wireless broadband in the campus as its impact on customers’ satisfaction as well as service quality at YES! campus store.
Demonstration of high-speed data transmission using MIMO-OFDM visible light communications

This letter reports an experimental demonstration of high-speed indoor optical wireless Optical multiple-input multiple-output (MIMO)-orthogonal frequency division multiplexing (OFDM) system with an imaging receiver. The system consists of a 2×1 array of white LEDs that transmit data to a 9 channel imaging receiver that uses a 3×3 photodetector array. A total transmission rate of 220Mbit/s at a BER of 10−3 is achieved over a range of 1m. An overview of the design specifications, optical design and experimental setup are reported in this letter, together with results and discussion of how improvements to the system may be achieved.
The Strata Model Predicting Advertising Effectiveness

ABSTRACT The use of neuroscience methods in advertising research continues to grow, but it remains controversial. One area of neuroscience that has the potential to advance understanding of consumer decision making is neural-network analysis. The authors draw a parallel between means–end decision theory and neural-network analysis. They then apply these two theoretical perspectives to validate empirically a recognized advertising-strategy assessment (Strata) model. The results of an analysis of 240 television advertisements offer support for the neural-network-based Strata model. The article concludes with recommendations for how to improve advertising effectiveness.
Personal values underlying halal food consumption: evidence from Indonesia and Malaysia

Purpose The purpose of this paper is to uncover the personal values driving Indonesian and Malaysian Muslims’ consumption decisions with respect to halal food. Design/methodology/approach The personal values of 130 Indonesian and 80 Malaysian Muslims have been analyzed, using a means-end chain (MEC) approach, in relation to halal food. Findings Primary personal values are identified as a better sense of personal security. This is ascribed as seeking “better future” and “go to heaven. ” Other personal values are related to tradition, benevolence and achievement. Research limitations/implications Since this study was conducted in both the capital cities of Indonesia and Malaysia, this study might not take account of cultural diversity within the two countries’ Muslim communities. Practical implications An understanding of the personal values governing Muslim consumption is a useful tool toward improving the promotion of halal certification and food products. Originality/value This study reveals the personal values of Indonesian and Malaysian Muslims with underpinning their consumption of halal food.
A Multi-Session Attribution Modification Program for Children with Aggressive Behaviour: Changes in Attributions, Emotional Reaction Estimates, and Self-Reported Aggression

Background: Research suggests that aggressive children are prone to over-attribute hostile intentions to peers. Aims: The current study investigated whether this attributional style can be altered using a Cognitive Bias Modification of Interpretations (CBM-I) procedure. Method: A sample of 10–12-year-olds selected for displaying aggressive behaviours was trained over three sessions to endorse benign rather than hostile attributions in response to ambiguous social scenarios. Results: Compared to a test-retest control group (n = 18), children receiving CBM-I (n = 16) were less likely to endorse hostile attributions and more likely to endorse benign attributions in response to a new set of ambiguous social situations. Furthermore, aggressive behaviour scores reduced more in the trained group than in the untrained controls. Children who received attribution training also reported less perceived anger and showed a trend to report more self-control than those in the control group. Conclusions: Implications of these findings are discussed.
Effects of natural ventilation on leaf ultrastructure of Dianthus caryophyllus L. cultured in vitro

SummaryVessel closure configurations exert direct and indirect control over factors pertaining to the physical boundaries of the mieroenvironment, and induce a typical phenotype in in vitro plant production. Upon modification of the in vitro environment, carnation explants showed a gradation of their ultrastructural characteristics from hyperhydric to normal. A higher degree of development was observed in plants from vessels with higher ventilation compared to ones from vessels with low ventilation rates. The cell walls of epidermal cells from both normal and hyperhydric plants grown in nonventilated vessels were less developed than those from plants grown in ventilated vessels. Cytoplasm of normal plants was dense and generally located in parietal areas. The cytoplasm was even more dense in plants grown in ventilated vessels and acclimated. The degree of thylakoid stacking and distribution were affected by ventilation conditions, being poorly developed with low ventilation. Ultrastructurally, stomata from in vitro plants are ready to carry out their task, although there are significant differences in guard cell size and vacuolar area between acclimated and in vitro plants.
Translation initiation in Escherichia coli: old and new questions

We discuss the features of Escherichia coli mRNAs which determine where and how efficiently translation is initiated. We have shown that DNA fragments comprising 60–80 nucleotides that bracket the initiation codon of real genes generally promote translation when inserted within a foreign mRNA, while those not corresponding to an authentic gene start do not do so even if they include a Shine‐Dalgarno‐like element followed by AUG or GUG. Therefore, the information that pinpoints the correct start sites, while extending beyond the mere presence of these elements, remains essentially local. The possible nature of this information is discussed. Next, we point out that, in order to remain accessible, translational starts must escape long‐range base‐pairing within large mRNAs, and we argue that the tight coupling between translation and transcription plays an important role in achieving this. Finally, we discuss two intriguing situations in which the initiation frequency should be dependent upon the rate of translation elongation.
Political Approaches to Tackling Islamophobia: An ‘Insider/Outsider’ Analysis of the British Coalition Government’s Approach between 2010–15

Soon after the Conservative-led Coalition government came to power in 2010, Baroness Sayeeda Warsi announced that Islamophobia had passed the ‘dinner-table test’ in contemporary Britain. Resultantly, the need to address Islamophobia was identified as a priority for the Coalition. This article critically analyses how the Coalition sought to achieve this and the extent to which it was successful. Focusing on the period 2010–15, this article initially frames what is meant by Islamophobia, before briefly setting out how it had been responded to by previous British governments. Regarding the Coalition, a threefold approach is adopted that considers the All-Party Parliamentary Group on Islamophobia, the Cross-Government Working Group on Anti-Muslim Hate, and the political discourses used by the Coalition about Muslims and Islam more generally. Concluding that the Coalition failed to meet the high expectations set by Warsi’s speech, this article considers why this might have been so.
The healing of tibial fracture and response of the local lymphatic system.

BACKGROUND Damage of tissues by mechanical injury and inflammation is followed by reaction of the regional lymphoid tissue, lymphatics, and lymph nodes. In our previous lymphoscintigraphic studies, we showed that closed fractures of a lower limb cause reaction of the local lymphoid tissue. There was dilation of lymphatics draining the site of the fracture and enlargement of inguinal lymph nodes. These changes persisted even after clinical healing of the fracture. In the long-lasting nonhealing fractures, the lymphoscintigraphic pictures were different. The draining lymphatics became obliterated, and the lymph nodes disappeared. METHODS In this study, we tried to correlate the lymphoscintigraphic images, reflecting the immune events at the fracture site, with the immunohistochemical observations of the biopsy specimens obtained during corrective operations from the healing and nonhealing fracture gaps. Thirty-eight patients with closed fracture of the tibia without traumatic skin changes were studied. RESULTS We confirmed that closed tibial fracture evokes response of the regional lymphatic system. Normal fracture healing with immune cell infiltrates and foci of ossification was accompanied by dilated lymphatics and enlarged lymph nodes. Prolonged nonhealing fracture with lack of cellular reaction in the gap proceeded with decreased mass of lymph nodes. CONCLUSION This study provides evidence for existence of a functional axis between wound of bone and surrounding soft tissue and the local lymphatic (immune) system. We hypothesize that the fast healing is regulated by influx into the wound of lymph node regulatory cells, whereas prolonged healing causes gradual exhaustion of the regional lymph node functional elements, and reciprocally impairment in sending regulatory cells to the fracture gap.
Models in information behaviour research

This paper presents an outline of models of information seeking and other aspects of information behaviour, showing the relationship between communication and information behaviour in general with information seeking and information searching in information retrieval systems. It is suggested that these models address issues at various levels of information behaviour and that they can be related by envisaging a ‘nesting’ of models. It is also suggested that, within both information seeking research and information searching research, alternative models address similar issues in related ways and that the models are complementary rather than conflicting. Finally, an alternative, problem‐solving model is presented, which, it is suggested, provides a basis for relating the models in appropriate research strategies.
Multi-constrained IIR filter design using PSO

In this study, IIR (Infinite Impulse Response) filters having a null and the specified error in a stop band are designed using PSO (Particle Swarm Optimization). A new penalty term to form a null is introduced to an objective function in addition to the conventional penalty function that ensures the stability of IIR filters. Furthermore, the specified error is restricted in the objective function. A design problem based on the minimax criteria is formulated as the non-linear optimization problem and cannot be solved easily. In addition, adding such constraints bring to local minima to the objective function. PSO is applicable to solve such non-linear optimization problems. However, it is reported that a local minimum stagnation occurs due to the strong intensification characteristic. Therefore, it is important to avoid the local minimum stagnation. In our method, a particle reallocation strategy is applied when the stagnation occurs. The effectiveness of our method is verified through several design examples.
Exploiting holistic computation : an evaluation of the sequential RAAM

In recent years it has been claimed that connectionist methods of representing compositional structures, such as lists and trees, support a new form of symbol processing known as holistic computation. In a holistic computation the constituents of an object are acted upon simultaneously, rather than on a one-by-one basis as is typical in traditional symbolic systems. This thesis presents firstly, a critical examination of the concept of holistic computation, as described in the literature, along with a revised definition of the concept that aims to clarify the issues involved. In particular it is argued that holistic representations are not necessary for holistic computation and that holistic computation is not restricted to connectionist systems. Secondly, an evaluation of the capacity of a particular connectionist representation, the Sequential RAAM, to generate representations that support holistic symbol processing is presented. It is concluded that the Sequential RAAM is not as effective a vehicle for holistic symbol processing as it initially appeared, but that there may be some scope for improving its performance.
Optical Information and Practice in the Discrimination of 3-D Mirror-Reflected Objects

Two studies of the discrimination of three-dimensional mirror-reflected objects were concerned with the influence of practice and stimulus information for shape, specifically binocular information and perspective transformations. In the first study subjects made ‘same-different’ responses to successively presented pairs of real objects, under binocular and monocular viewing conditions. In the second study subjects viewed object pairs on a rotating turntable, in five different displays. Neither binocular information nor perspective transformations contributed to isomorph discrimination. In both studies mental rotation and other less well specified strategies were employed. After practice, in contrast to previous reports, five of the six subjects in these studies produced reaction times unrelated to the orientation difference between the objects. These practice effects may reflect either extremely rapid rotation rates, the detection of rotationally invariant features, or the use of multiple strategies.