Miracle-dz/UniFAR-FTUs huggingface dataset:
Essential Assessment Parameters Thais

on the clinical performance of short implants and, under these circumstances, determine the reasons for implant failure. This study evaluated, through a systematic review of the literature and meta-analysis, the essential parameters required to assess the long-term clinical performance of short and extra-short implants. Electronic databases (PubmedMEDLINE, Cochrane Library Database, Embase, and Lilacs) were searched by two independent reviewers, without language limitation, to identify eligible papers. References from the selected articles were also reviewed. The review included clinical trials involving short dental implants placed in humans, published between January 2000 and March 2014, which described the parameters applied for outcome’s measurements and provided data on survival rates. Thirteen methodologically acceptable studies were selected and 24 parameters were identified. The most frequent parameters assessed were the marginal bone loss and the cumulative implant survival rate, followed by implant failure rate and biological complications such as bleeding on probing and probing pocket depths. Only cumulative implant survival rate data allows meta-analysis revealing a positive effect size (from 0.052 (fixed) to 0.042 (random)), which means that short implant appears to be a successful treatment option. Mechanical complications and crown-to-implant (C/I) ratio measurement were also commonly described, however, considering the available evidence; no strong conclusions could be drawn since different methods were used to assess each parameter. By means of this literature review, a standard evaluation scheme is proposed, being helpful to regiment further investigations and comparisons on future studies. L o n g t e r m S h o r t I m p l a n t s Performance: Systematic Review a n d M e t a A n a l y s i s o f t h e Essential Assessment Parameters
Deposited in DRO : 27 November 2014 Version of attached le : Accepted Version Peer-review status of attached

Let C be two times continuously differentiable curve in R with at least one point at which the curvature is non-zero. For any i, j > 0 with i + j = 1, let Bad(i, j) denote the set of points (x, y) ∈ R for which max{∥qx∥, ∥qy∥} > c/q for all q ∈ N. Here c = c(x, y) is a positive constant. Our main result implies that any finite intersection of such sets with C has full Hausdorff dimension. This provides a solution to a problem of Davenport dating back to the sixties.
Disassociation Between Intracranial and Systemic Temperatures as an Early Sign of Brain Death

Intracranial temperature and its normal variation, as well as its response to various pathologic conditions, has become a critical component of monitoring in neurosurgical intensive care. In a prospective clinical study of 54 neurosurgical patients, intracranial pressure, cerebral perfusion pressure, and intraventricular and systemic temperatures were monitored in a neurosurgical intensive care unit. All of our patients' intraventricular temperatures were initially higher than their systemic temperatures. In 11 patients, the intraventricular temperature became lower than the systemic temperature, in a median time of 4.43 hours (range, 4.21–5.18 hours), prior to any changes in intracranial and cerebral perfusion pressures. Reversal of the disassociation between intraventricular and systemic temperatures may be an early marker of patients with a poor prognosis.
Propagation of Canine Distemper Virus on the Chorio-Allantolc Membrane of Embryonated Hen Eggs

Summary Studies are reported in which the Lederle stock strain of canine distemper virus was adapted and maintained through 74 serial passages on the chorio-allantoic membranes of developing chick embryos. The chick embryo adapted strain retained its capacity to produce lethal infection in ferrets through the 24th egg passage level but apparently lost its ability to do so between the 24th and 28th egg passages. Ferrets inoculated with chick embryo adapted virus of passage levels higher than the 28th transfer failed to show any signs of disease, but were found immune on rechallenge with fully virulent ferret spleen virus. Cross neutralization tests carried out in chick embryos and in ferrets indicate that the chick embryo adapted strain and the parent strain of ferret spleen virus are immunologically related.
Burrow use and the influence of ectoparasites in Brants' whistling rat Parotomys brantsii

In Brants’ whistling rat, Parotomys brantsii, single animals inhabit unusually complex burrow systems containing several nest chambers. We investigated burrow use and examined the effect of ectoparasites on choice of alternative nest chambers by radiotelemetrically monitoring the nocturnal sleeping locations of individual whistling rats, before and after treating themto rem ove ectoparasites. Prior to treatment, animals used several different nest chambers within a single burrow, moving from one chamber to another every 1.6 d on average, and most individuals also slept in more than one burrow. Anti-parasite treatment reduced the rate at which animals switched from one nest chamber to another within a burrow. Screening of a separate sample of animals for ectoparasites revealed that they were infested with fleas, mainly Xenopsylla eridos. We suggest that by switching periodically fromone nest chamber to another, whistling rats reduce the rate at which ectoparasites, especially fleas, accumulate.
Perceived Environmental and Personal Factors Associated with Walking and Cycling for Transportation in Taiwanese Adults

This study examined perceived environmental and personal factors associated with walking and cycling as means of transportation for Taiwanese adults. A random-digit-dialing telephone-based cross-sectional survey was conducted with Taiwanese adults aged 20 to 64 years. Data on time spent walking and cycling for transportation and perceptions of neighborhood environment and personal characteristics were obtained from 1065 adults by using the International Physical Activity Questionnaire-long version and its environmental module. Adjusted binary logistic regression was performed. The results showed that, after adjusting potential confounders, common and different personal and perceived environmental factors were associated with walking and cycling for transportation. For common personal factors, adults who had employment were less likely to engage in 150 min of walking per week (odds ratio [OR] = 0.41; 95% confidence interval (CI): 0.27–0.62) and to use cycling as a means of transportation (OR = 0.51; 95% CI: 0.32–0.79). For common perceived environmental factors, adults who perceived good connectivity of streets were more likely to walk (OR = 1.95; 95% CI: 1.20–3.16) and cycle (OR = 2.02; 95% CI: 1.16–3.54) for transportation. Targeting employed adults and improving the connectivity of streets should be a priority for developing transport policies and intervention strategies to promote active transportation.
Momentary Work Happiness as a Function of Enduring Burnout and Work Engagement

ABSTRACT The present study (N = 136) combined global measures with specific, experience-based measures to investigate how enduring job burnout and engagement influence the impact of daily work activities on momentary need satisfaction and happiness. We used the day reconstruction method (DRM) to ask employees from various occupations to reconstruct their working days. On the basis of employee work engagement and self-determination theories, we hypothesized that time spent on (a) core work tasks; (b) administrative work tasks; (c) client interactions; (d) interactions with colleagues; and (e) meetings would be negatively related to need satisfaction on the task level for employees high (vs. low) in enduring burnout; and positively related to need satisfaction on the task level for employees high (vs. low) in enduring work engagement. In addition, we predicted that psychological need satisfaction would mediate the relationships between time spent on work tasks and happiness during the tasks. The results of multilevel analyses largely supported these hypotheses. Our findings contribute to the literature by showing how those with high levels of burnout do not manage to satisfy their basic needs through their work, whereas those with high levels of work engagement satisfy their daily needs and stay happy.
On a System of Two Nonlinear Difference Equations

Abstract In this paper we study the oscillatory behavior, the boundedness of the solutions, and the global asymptotic stability of the positive equilibrium of the system of two nonlinear difference equationsxn + 1 = A + yn/xn − p,yn + 1 = A + xn/yn − q,n = 0, 1,…,p, qare positive integers.
Delay of Gratification and Delay Maintenance by Rhesus Macaques (Macaca Mulatta)

The authors tested the self-control of rhesus macaques by assessing if they could refrain from reaching into a food container to maximize the accumulation of sequentially delivered food items (a delay-maintenance task). Three different versions of the task varied the quantity and quality of available food items. In the first 2 versions, food items accumulated across the length of the trial until a monkey consumed the items. In the 3rd task, a single less-preferred food item preceded a single more-preferred food item. Some monkeys delayed gratification even with relatively long delays between deliveries of items. However, the data suggested that self-control, in the majority of tested individuals, was not significantly different across different task versions and that self-control by macaques was not as prevalent in these tasks as it is in chimpanzees and human children.
DNA Mismatch Repair Deficiency in Colorectal Adenocarcinoma and its Association with Clinicopathological Features

Background: Evaluation of mismatch repair (MMR) status in colorectal cancer (CRC) could be used as the guidance for postsurgical treatment. Defective MMR status is associated with distinct clinicopathological features. This study aims to evaluate associations between MMR status and clinicopathological features in a retrospective cohort of consecutive Chinese CRC patients. Methods: Clinicopathological information was collected from 481 consecutive individuals who underwent curative surgery for CRC. MMR status was determined by Immunohistochemistry (IHC) staining, which was used to examine expression of MLH1, PMS2, MSH2 and MSH6 on paraffin embedded tissues containing adenocarcinoma. Results: IHC results showed that 33 (of 481, 6.9%) CRC cases presented loss of MMR proteins expression, including 26 (of 205, 12.7%) from colon and 5 (of 262, 1.9%) from rectum. Tumors with deficient DNA mismatch repair (dMMR) status were significantly related to younger patients, larger tumor size, mucinous-focal or signet-ring histological phenotype, and preferred right-sided location (P<0.001). And dMMR tumors also implied poor differentiation and more occurrence in stage CRC patients. No significant association was found between MMR status and gender, invasion depth and lymph node metastasis. Conclusions: We concluded that the prevalence of abnormal MMR protein expression in this cohort of Chinese CRC patients was comparable with the West. Meanwhile, tumors with dMMR status were associated with distinct clinicopathological characteristics of CRC patients.
Clinical Utility of SPECT-(Low-Dose)CT Versus SPECT Alone in Patients Presenting for Bone Scintigraphy

Purpose: This prospective study evaluated the contribution of single-photon emission computed tomography (SPECT)-(low-dose)CT (SPECT-ldCT) over SPECT alone in all-comers referred for bone scintigraphy for any indication. Methods: In this prospective study, imaging was performed on 100 consecutive patients who presented for bone scintigraphy using a combined SPECT-ldCT single-gantry system (Brightview XCT, Philips Medical Systems Inc., Cleveland, OH). SPECT images were reconstructed with (AC) and without (NAC) attenuation and scatter correction. SPECT (NAC), SPECT-ldCT (NAC), and SPECT-ldCT (AC) were reviewed independently and in a blinded manner. Reader interpretation of images was compared with the final clinical diagnosis. Results: Subjects were referred for oncologic (28%) and nononcologic (72%) indications. Attenuation correction significantly improved perceived image quality (P = 0.012), but did not significantly alter diagnostic confidence (P = 0.96). Availability of ldCT data during interpretation of the SPECT images yielded a significant increase in the level of diagnostic confidence (P < 0.001). When the ldCT data were available, 18 of 200 bone SPECT reads recommended additional diagnostic CT imaging, compared with 70 when ldCT data were unavailable at the time of reading (P < 0.001). The sensitivity, specificity, and accuracy of SPECT-ldCT (with or without attenuation and scatter correction) in the diagnosis of osseous processes were 90.9%, 85.9%, and 87.0%, respectively, and these values did not differ significantly from those obtained with SPECT alone. Conclusions: Bone SPECT-ldCT provides interpreting physicians a significantly greater level of diagnostic confidence and reduces additional diagnostic imaging studies, but the overall diagnostic accuracy of SPECT-ldCT was not affected when compared with SPECT alone, suggesting that SPECT-ldCT should be used on a patient-by-patient basis.
Humoral immunological response in broilers vaccinated against newcastle disease and supplemented with dietary zinc and vitamin E

The humoral immune response of broilers fed diets supplemented with Zinc (Zn) (0, 40, and 400mg/kg) and vitamin E (0, 12, and 120mg/ kg), separately or combined, was evaluated. A completely randomized design was used according to a 3x3 factorial arrangement, with nine treatments and four repetitions per treatment. Sexed birds (n=1440) were distributed in 36 boxes with 40 chicks each and reared until 41 days of age. Vaccination against Newcastle Disease (ND) was performed when birds were 14 days old. ELISA and HI tests were used to assess antibody levels before vaccination and at 28, 35 and 41 days of age. The results were analyzed using Proc Mixed from SAS. The interaction between the highest dietary levels of Zn and vitamin E resulted in higher antibody levels in ELISA at 14, 28, 35 and 41 days of age. Increasing levels of Zn and vitamin E supplemented separately in the diets provided greater levels of hemagglutinating antibodies in HI at 14, 28, 35 and 41 days old. The interaction between the highest levels of Zn and vitamin E resulted in greater antibody levels at 41 days of age.
Dynamically Organizing KDD Processes

How to increase both autonomy and versatility of a knowledge discovery system is a core problem and a crucial aspect of KDD (Knowledge Discovery and Data Mining). Within the framework of the KDD process and the GLS (Global Learning Scheme) system recently proposed by us, this paper describes a way of increasing both autonomy and versatility of a KDD system by dynamically organizing KDD processes. In our approach, the KDD process is modeled as an organized society of KDD agents with multiple levels. We propose an ontology to describe KDD agents, in the style of OOER (Object Oriented Entity Relationship) data model. Based on this ontology of KDD agents, we apply several AI planning techniques, which are implemented as a meta-agent, so that we might (1) solve the most difficult problem in a multiagent KDD system: how to automatically choose appropriate KDD techniques (KDD agents) to achieve a particular discovery goal in a particular application domain; (2) tackle the complexity of KDD process; and (3) support evolution of KDD data, knowledge and process. The GLS system, as a multistrategy and multiagent KDD system based on the methodology, increases both autonomy and versatility.
Nasopharyngeal carcinoma: clinical assessment and review of 176 cases.

OBJECTIVE The objective of this study was to delineate salient disease characteristics and to determine factors associated with survival in a series of patients with nasopharyngeal carcinoma (NPC). STUDY DESIGN To address our research objective, we used a retrospective cohort study design and a sample of patients who presented for evaluation and management of NPC. Demographic data, medical history, radiographic findings, staging, and histology were recorded. Treatment and follow-up information were ascertained. Survival data and descriptive statistics were calculated. Multivariate analyses identified risk factors associated with survival rates for all World Health Organization (WHO) types. RESULTS The sample comprised 123 men and 53 women (n = 176) of which 70% were white and 23% were Asian. A neck mass was the initial symptom in 49% of patients. In 99% of cases, radiation therapy was the primary treatment mode. WHO types 1 and 3 were most common. Overall 5-year disease-free survival rate was 45.5%. Age, use of tobacco or ethanol, and number of presenting symptoms were statistically associated with decreased survival rate in WHO 1 (squamous cell) tumors. Male gender and total number of presenting symptoms were associated with decreased survival rate for WHO 2 and 3 (nonkeratinizing or undifferentiated) tumors. CONCLUSIONS Being attuned to the presenting signs of NPC may lead to a more expedient diagnosis. The differing risk factors associated with WHO 1 tumors become clear in this predominantly white population.
Effects of hypo or hyper‐thyroidism on growth hormone‐binding protein

Summary. objective Growth hormone (GH) receptors are Influenced by the thyroidal state of experimental animals. It has been suggested that GH‐binding protein (BP) might serve as an Indirect measure of the GH receptors. The present study was undertaken to investigate the growth hormone binding protein in patients with hypo or hyperthyroidism.
Öğretim Sürecinde Bilgisayara Dayalı Alıştırma Amaçlı Oyun Kullanılmasının Eğitim Fakültesi Öğrencilerinin Akademik Başarısına Etkisi

Th e aim of this study is to define whether using exercise-based games increase the performance of learning. For this reason, two basic questions were tried to be answered in the study. First, is there any diff erence in learning between the group that was given exercisebased games and the group that was not? Second, is there any diff erence in learning between the group that used exercise-based games at end of the process of learning and the group that was not applied this but taken the questions of exercises in game material? Th is research has been conducted within the subject of Testing and Evaluation in the program of Kocaeli University Primary Maths Teacher’s College. Experimental design with a pre test-post test control group was used in this study. Experimental process based on game material was used in 120 minutes at the end of a 3-week-teaching period. Th e reliability values (KR-20) of the two tests were found to be . 79 and . 71 which were used to evaluate learning level. Th e study has reached a conclusion that game materials used at the end of learning process have increased the learning levels of teacher candidates. However, the similar learning levels have been observed among students who were taken printed exercises instead of using learning game method to reinforce the traditional learning in the research. Th is means that in method of applying teaching games in addition to the traditional teaching, there isn’t any diff erence of learning eff iciency of students answered the questions based on competition and fun and the group who only answered the questions. Th is study is expected to contribute defining in which situations games are eff ective.
Helicase-primase inhibitor pritelivir for HSV-2 infection.

BACKGROUND Pritelivir, an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. We tested the efficacy and safety of pritelivir in otherwise healthy persons with genital HSV-2 infection. METHODS We randomly assigned 156 HSV-2-positive persons with a history of genital herpes to receive one of four doses of oral pritelivir (5, 25, or 75 mg daily, or 400 mg weekly) or placebo for 28 days. Participants obtained daily swabs from the genital area for HSV-2 testing, which was performed with a polymerase-chain-reaction assay. Participants also maintained a diary of genital signs and symptoms. The primary end point was the rate of genital HSV shedding. RESULTS HSV shedding among placebo recipients was detected on 16.6% of days; shedding among pritelivir recipients was detected on 18.2% of days among those receiving 5 mg daily, 9.3% of days among those receiving 25 mg daily, 2.1% of days among those receiving 75 mg daily, and 5.3% of days among those receiving 400 mg weekly. The relative risk of viral shedding with pritelivir, as compared with placebo, was 1.11 (95% confidence interval [CI], 0.65 to 1.87) with the 5-mg daily dose, 0.57 (95% CI, 0.31 to 1.03) with the 25-mg daily dose, 0.13 (95% CI, 0.04 to 0.38) with the 75-mg daily dose, and 0.32 (95% CI, 0.17 to 0.59) with the 400-mg weekly dose. The percentage of days with genital lesions was also significantly reduced, from 9.0% in the placebo group to 1.2% in both the group receiving 75 mg of pritelivir daily (relative risk, 0.13; 95% CI, 0.02 to 0.70) and the group receiving 400 mg weekly (relative risk, 0.13; 95% CI, 0.03 to 0.52). The rate of adverse events was similar in all groups. CONCLUSIONS Pritelivir reduced the rates of genital HSV shedding and days with lesions in a dose-dependent manner in otherwise healthy men and women with genital herpes. (Funded by AiCuris; ClinicalTrials.gov number, NCT01047540.).
Directly observed therapy for tuberculosis in a low prevalence region: first experience at the Tuberculosis Dispensary in Lausanne.

AIM Evaluation of first experience of the directly observed therapy (DOT) programme for tuberculosis introduced in the Canton of Vaud in 1997. METHOD Retrospective analysis of tuberculosis patients included in a DOT programme from October 1997 to March 2000 under the supervision of the TB Dispensary in Lausanne. RESULTS 54 patients were included, 49 of whom were new cases and 5 relapses. 70% were asylum seekers and illegal immigrants. The indications for DOT were immigrant status, social problems, and physical or psychiatric comorbidities. Treatment was fully supervised in 67% and partially in 33%. The outcome was favourable (cure or treatment completion) in 88.9% and unfavourable in 11.1%. A similar success rate was observed in full and partial DOT and there was no difference in success rates between the various structures where DOT was administered. By comparison, the success rate in a historical group from the same institution was 70% in 1990. The biggest problem was communication with the patients and within the team. CONCLUSION Treatment of tuberculosis under DOT in the Canton of Vaud resulted in improvement of the treatment success rate.