Miracle-dz/UniFAR-FTUs huggingface dataset:
The 2012 Olympic Ambassadors and sustainable tourism legacy

ABSTRACT This paper examines the capacity of the London (2012) Olympic Ambassador volunteer programmes to create a sustainable tourism legacy. It contributes to the literature on event legacies, particularly the role of volunteers promoting tourism in their home destination. Using an exploratory inductive approach, semi-structured in-depth interviews were conducted, in 2012 and 2013, with managers of all 11 Ambassador volunteer programmes associated with London and the 10 other regional venues that hosted London Olympic and Paralympic Games events. These show that volunteer Ambassadors enhanced tourist experiences during the Games through the Ambassadors’ pride in their home city, enthusiasm and local knowledge. However, although the Ambassador programmes had aspirations to create a sustainable legacy, in the form of a pool of experienced volunteers to support future events and further tourist visits, this was severely constrained by cuts in local government budgets. The Government Olympic Executive provided a coordinating role leading up to the Games, but neither they nor the London Organising Committee for the Olympic Games provided practical assistance for legacy development. This was a missed opportunity to channel the enthusiasm of mega-event volunteers into further volunteering to promote tourism.
Tax arrears amongst individual income taxpayers in Malaysia

Purpose The purpose of this paper is to investigate the relationship between tax arrears and socio-psychological demographic factors on individual taxpayers as well as macroeconomic factors in Malaysia. Design/methodology/approach In this study, using proprietary data from Inland Revenue Board of Malaysia on individual income tax returns for the year of 2004 through 2012, the authors run a panel data fixed effect model analysis to examine the impact of socio-psychological demographic factors such as age, gender, marital status, income level, occupational sector, place of residence of individual tax payers as well macroeconomic factors such as real GDP, inflation and economic growth on tax arrears in Malaysia. Findings We find that, by and large, older male taxpayers in big towns, with high incomes, tend to accumulate tax arrears. Tax arrears are also significantly affected by real GDP, but not by marital status or occupational sector. Originality/value To the best of our knowledge, this is one the few studies that uses individual tax returns data to study determinants of tax arrears.
The effectiveness of a permaculture education project in Butula, Kenya

ABSTRACT In the 1980s, agricultural development organizations began promoting permaculture, an agroecological approach that emphasizes local autonomy, through training programmes in the developing world. Few assessments have measured the effectiveness of such projects. Here we surveyed and interviewed small-scale farmers to assess the perceived impacts of a Canadian permaculture non-governmental organization’s (NGO) project in Butula, Western Kenya. Two types of projects are evaluated and compared: community projects (CPs) at six primary schools, and an intensive two-week permaculture design certification (PDC) programme. Our results suggest that both PDC and CP participants felt that they had benefited from the projects. However, PDC participants developed a more comprehensive understanding of permaculture, felt empowered and frequently related permaculture to their own traditional cultural values whereas CP participants often misunderstood permaculture, felt frustrated by the limited immediate economic benefits and frequently contrasted permaculture against traditional cultural values. These differences may have occurred because CP participants had fewer opportunities to interact directly with the permaculture teachers, to ask questions, or to clarify points of uncertainty. This study emphasizes the importance of direct, reciprocal communication between NGOs and project participants for fostering feelings of autonomy and competence, thereby strengthening resilient agroecological systems.
Role of polymorphic N‐acetyl transferase2 and cytochrome P4502E1 gene in antituberculosis treatment‐induced hepatitis

Background and Aim: Antituberculosis drugs, isoniazid and rifampicin, in combination, are known to develop drug‐induced hepatotoxicity (DIH). A higher risk of DIH during antituberculosis treatment (ATT) has been reported in the Indian subcontinent compared to its Western counterparts. The role of genetic factors in a higher incidence of ATT hepatotoxicity in the Indian population is still unclear. The present study was aimed at investigating the role of the N‐acetyltransferase2 (NAT2) and cytochrome P4502E1 (CYP2E1) gene polymorphisms in ATT hepatotoxicity.
(When) Should We Use Foreign Direct Investment Data to Measure the Activities of Multinational Corporations? Theory and Evidence

This paper reviews the different concepts of measuring activities of multinational corporations. It aims at working out the economic relationships that theoretically exist between these measures under general economic assumptions and then empirically investigates to which extent such relationships exist in the data. As a main conclusion, foreign direct investment (FDI) stock data is indeed a good proxy for measuring most real economic activities of multinational firms. Discrepancies between FDI stock and other data can to a large extent be given a reasonable economic meaning, but observed asset‐to‐employment patterns in multinational production also call for more thorough future research.
Time in residence affects escape and agonistic behavior in adult male american lobsters.

Acquisition and retention of a shelter by a lobster are two of the variables that play a role in lobster agonistic interactions. Since shelter procurement and retention are important for lobster survival, behaviors related to this activity frequently outrank other daily behaviors (e.g., searching for food). Here, we examine the effects of time in residence on the parameters of the escape response of the American lobster, Homarus americanus. Adult male intermolt lobsters (Stage C4) were placed in an experimental tank for three different time periods (one hour, 24 hours, and 48 hours). The probability of eliciting an escape response was inversely related to the time spent in the tank. Eighty percent of the animals in residence for 1 h tailflipped in response to a threat, whereas only 14% of the animals in residence for 48 h tailflipped. There were also significant changes in some of the parameters of the escape response among animals in residence for 24 h compared to those in residence for 1 h. The number of tailflips and the distance traveled were reduced, although frequency, velocity, acceleration, force, and work factors were not significantly different. Furthermore, with increased time in residence, lobsters switched from an avoidance or escape-prone behavior to an aggressive-prone behavior. Most of the animals in residence for 48 h approached and attacked a threat-stimulus rather than fleeing from it. On an empirically defined "index of aggressiveness," in which various behaviors were numerically ranked from least aggressive (0) to most aggressive (6), animals residing in the tank for 1 h had an average index value of 0.1 compared to a value of 5.0 for animals in residence for 48 h. These findings are consonant with the suggestion that lobsters that have occupied a given space for an extended period of time take possession of the site and defend it instead of fleeing when threatened with a threat-inducing stimulus; it supports the idea that shelter retention increases aggressiveness and diminishes avoidance behaviors.
Building Relationship Innovation in Global Collaborative Partnerships: Big Data Analytics and Traditional Organizational Powers

This study examines how relationship innovation can be developed in global collaborative partnerships (alliances, joint ventures, mergers, and acquisitions). The recently emerging theory of big data analytics linked with traditional organizational powers has attracted a growing interest, but surprisingly little research has been devoted to this important and complex topic. Therefore, after developing the theoretical foundations, our study empirically quantifies the links between the theoretical constructs based on the data collected from chief executive officers, managing directors, and heads of departments who work in contemporary global data-and-information driven collaborative partnerships. The results from structural equation modeling indicate that the relationship innovation depends on the power of big data analytics and non-mediated powers (NMP, expert and referent). The power of big data analytics also mediates the correlation between NMP and relationship innovation. However, mediated powers (coercive and manipulative) negatively affect the power of big data analytics and relationship innovation. The interaction effects further depict that analytically powered partnerships have better relationship innovation compared with those which focus less on the analytical power. Consequently, the contributions of this study provide a deeper understanding of mechanisms of how modern collaborative partnerships can use big data analytics and traditional organizational powers to co-create relationship innovation.
Point of sale tobacco displays and smoking among 14–15 year olds in New Zealand: a cross-sectional study

Objective: To examine the association between exposure to tobacco displays at the point of sale and teenage smoking and susceptibility to the uptake of smoking. Design: The sample comprised a national cross-section of 14–15 year olds with two measures of exposure to tobacco displays at the point of sale and three outcome measures. The outcome measures were susceptibility to smoking initiation, experimenting with smoking or current smoking. Results: Compared with visiting stores less often than weekly, a greater frequency of store visits was related to increased odds of being susceptible to smoking (daily visits, adjusted OR 1.8, 95% CI 1.6 to 2.2) and experimenting with smoking (daily visits, adjusted OR 2.7, 95% CI 2.4 to 3.1). The likelihood of being a current smoker increased with a greater frequency of store visits among students of medium and high socioeconomic status, but not among those of low socioeconomic status. Conclusion: Although these findings are cross-sectional in nature, they are consistent with the notion that greater exposure to tobacco displays at the point of sale increases youth smoking, and suggest display bans are needed.
Onset exercise hyperaemia in humans: partitioning the contributors

Using a step‐wise, reductionist approach we characterized the time course and degree to which mechanical, vasodilatory and cardiac mechanisms contribute to the increase in leg blood flow (LBF) at the onset of dynamic knee‐extensor exercise. Heart rate (HR) and LBF (ultrasound Doppler) were evaluated during (1) voluntary and (2) passive exercise in the seated position, (3) passive exercise in the supine position with the leg above the heart, and (4) passive exercise with measurements made in the non‐moving leg. In trials 2 and 3, the degree of change and time course of peak ΔHR (8.7 ± 2 bpm, seated; 10 ± 1 bpm, supine) and peak ΔLBF (518 ± 135 ml min−1, seated; 448 ± 179 ml min−1, supine) were similar, supporting the concept that the skeletal muscle pump was minimized. Even with the reduction of skeletal muscle pump and metabolic influences (trials 2, 3 and 4) a significant cardio‐acceleration and hyperaemia was seen. In the first 5 s of seated passive exercise, the retrograde component of the blood velocity profile was significantly greater than rest or the 5–20 s interval, which may suggest an arterial inflow that initially exceeded leg vasodilatation. Steady‐state LBF (minutes 2 and 3) remained elevated during voluntary exercise, but returned to near baseline during passive movement. Taken together, these data suggest that cardio‐acceleration (i.e. tachycardia) and mechanical forces other than the skeletal muscle pump play a role in reducing vascular resistance and ultimately increasing LBF at the onset of exercise, followed by steady‐state LBF which matches muscle metabolic demand.
Postresuscitation disease after cardiac arrest: a sepsis-like syndrome?

Purpose of reviewDespite advances in cardiac arrest resuscitation, neurologic impairments and other organ dysfunctions cause considerable mortality and morbidity after restoration of spontaneous cardiac activity. The mechanisms underlying this postresuscitation disease probably involve a whole-body ischemia and reperfusion syndrome that triggers a systemic inflammatory response. Recent findingsPostresuscitation disease is characterized by high levels of circulating cytokines and adhesion molecules, the presence of plasma endotoxin, and dysregulated leukocyte production of cytokines: a profile similar to that seen in severe sepsis. Transient myocardial dysfunction can occur after resuscitation, mainly as a result of myocardial stunning. However, early successful angioplasty is independently associated with better outcomes after cardiac arrest associated with myocardial infarction. Coagulation abnormalities occur consistently after successful resuscitation, and their severity is associated with mortality. For example, plasma protein C and S activities after successful resuscitation are lower in nonsurvivors than in survivors. Low baseline cortisol levels may be associated with an increased risk of fatal early refractory shock after cardiac arrest, suggesting adrenal dysfunction in these patients. SummaryPostresuscitation abnormalities after cardiac arrest mimic the immunologic and coagulation disorders observed in severe sepsis. This suggests that therapeutic approaches used recently with success in severe sepsis should be investigated in patients successfully resuscitated after cardiac arrest.
Efficacy of DNA barcoding for the species identification of spiders from Western Ghats of India

Abstract DNA barcoding has emerged as an additional tool for taxonomy and as an aid to taxonomic impediments. Due to their extensive morphological variation, spiders are taxonomically challenging. Therefore, all over the world, attempts are being made to DNA barcode species of spiders. Till now no attempts were made to DNA barcode Indian spiders despite their rich diversity. We have generated DNA barcodes for 60 species (n = 112) of spiders for the first time from India. Although only 17 species were correctly identified at the species level, DNA barcoding correctly discriminated 99% of the species studied here. We have also found high intraspecies nucleotide divergence in Plexippus paykulli suggesting cryptic diversity that needs to be studied in detail. Our study also showed non-specific amplification of the Cytochrome Oxidase I (COI) gene of endosymbiont bacteria Wolbachia. However, these cases are very rare and could be resolved by the use of modified or group specific primers.
Differential Effects of Trimipramine and Fluoxetine on Sleep in Geriatric Depression

The effects of trimipramine, a tricyclic antidepressant (TCA) with atypical pharmacological properties, and fluoxetine, a selective serotonine reuptake inhibitor (SSRI), were compared in an exploratory analysis using mood and polysomnographic parameters during a six-week double-blind trial in 19 depressed geriatric patients. In sleep EEG measures, trimipramine demonstrated clear-cut effects on sleep measures resulting in higher values for sleep efficiency, total sleep time, stage 2 sleep, and shorter wake time. Under fluoxetine treatment, the proportion of REM sleep was decreased and REM latency was lengthened, whereas no change in REM sleep parameters was observed in the trimipramine group. The present data suggest that early antidepressant effects of medication occur independently of drug-induced changes in objective measures of sleep, i.e. suppression of REM sleep.
Evaluation of masticatory performance and bite force in children with sleep bruxism.

The aim of this study was to evaluate the association between masticatory performance (MP) and bite force (BF) in children with sleep bruxism (SB) during the mixed dentition stage, considering also the occlusal characteristics. The sample was composed by 52 healthy children of both genders, aged 6-10 years. From those, 22 presented signs and symptoms of SB and 30 were the controls. SB diagnosis consisted of both parental report and presence of tooth wear. MP was evaluated by the individual's ability to communicate an artificial chewable test material for determining the median particle size (X50) and distribution of particles in the different sieves (b). BF was measured using a digital gnathodynamometer with fork strength of 8 mm. The results were submitted to descriptive statistics, Mann-Whitney and chi-square tests, Spearman's correlation and multiple logistic regression. Mean BF and X50 did not differ between groups with and without SB. A significant negative correlation was observed between BF and X50 only in the group of children with SB. Moreover, the logistic regression model showed an association between the presence of SB and higher b index. The other independent variables included in the model showed no association with SB. BF did not differ between children with and without SB. Besides, higher BFs in children with SB meant better MP; however, they were more likely to present chewed particles retained in the larger aperture sieves, consequently requiring more chewing cycles to break down the test material in smaller particles.
Ecuador: Creating Fiscal Space for Poverty Reduction: A Fiscal Management and Public Expenditure Review. Volume I

This report consists of two volumes. Volume I examines whether, and how, the core goals of public expenditure management, i.e., balanced fiscal aggregates, resource allocations to strategic sectors, and equity and microeconomic efficiency of public spending are met in Ecuador. Volume II presents sector studies on fiscal sustainability, the fiscal rules, education, health, pensions, the results of a national teachers tracking survey, water and sanitation, electricity, telecommunications and oil.
Postembryonic expression of Caenorhabditis elegans mab‐21 and its requirement in sensory ray differentiation

The male tail sensory rays in Caenorhabditis elegans are complex copulatory structures, the normal patterning of which requires a number of regulatory genes. Among them, mab‐21 specifies the identity of sensory ray 6. By using green fluorescent protein reporters, we identify multiple cis‐acting elements that control the developmental expression of mab‐21. Traced with a functional mab‐21:gfp gene driven by authentic regulatory sequences, mab‐21 expression could be detected in hypodermal, neuronal, muscle, and ray cells. We showed here that the expression of mab‐21 in the hypodermis and neuronal cells was dispensable for its function in ray 6. In contrast, its expression in the ray 6 structural cell and neurons as conferred by its 3′ enhancer was crucial for determining the correct ray 6 identity. © 2001 Wiley‐Liss, Inc.
Exchange Rate Regimes and Welfare Losses from Foreign Crises: The Impact of the US Financial Crisis on Mexico

We modify the Gali and Monacelli small open economy dynamic stochastic general equilibrium (DSGE) model, calibrate to Mexican data and simulate the impact of the financial crisis on Mexico, under floating and counter factual fixed exchange rates. The floating exchange rate ameliorates welfare losses for Mexico. They are greater under fixed exchange rates because the return paths to equilibrium are more volatile (higher variance) and output, consumption and employment impulse response functions (IRFs) overshoot. Monetary policy, inflation targeting with floating exchange rates, clearly reduced the welfare costs vis‐a‐vis other counter factual policies including consumer price index‐based Taylor rule, domestic inflation Taylor rule and fixed exchange rates.
An examination of trait, spontaneous and instructed emotion regulation in dysphoria

Depression is thought to be characterised by impaired emotion regulation, although the mechanisms of that regulation are not yet well understood. The present study examined trait, spontaneous and instructed emotion regulation in dysphoric (n = 66) and non-dysphoric (n = 86) participants. Participants were randomly assigned to use reappraisal while watching a sadness-inducing film clip (instructed emotion regulation condition) or were not given specific viewing instructions (spontaneous emotion regulation condition). Participants also completed trait measures of emotion regulation. Dysphoric individuals reported greater spontaneous use of rumination and suppression than non-dysphoric individuals, and these strategies were associated with greater negative emotional reactivity to the sadness-inducing film clip. Both participant groups were able to effectively use reappraisal when instructed to do so. The clinical implications of these findings and future research directions are discussed.
Collision tumor composed of Merkel cell carcinoma and lentigo maligna melanoma

We report the case of an immunocompetent 79‐year‐old white man with a history of melanoma in situ on the back with a collision tumor composed of a Merkel cell carcinoma (MCC) and lentigo maligna melanoma on the left cheek. The cells of the MCC expressed cytokeratin 20 (CK 20) in a diffuse cytoplasmic pattern, AE1 and AE3 in a perinuclear dot‐like pattern and diffusely with neuron‐specific enolase. The tumor cells of the MCC failed to express thyroid transcription factor‐1. The atypical melanocytes of lentigo maligna melanoma expressed Melan‐A and S‐100. At the same visit, a lentigo maligna was diagnosed by excisional biopsy on the right cheek. The variability in expression of CK 20, AE1 and AE3 in MCC are reviewed. Prior reports of MCC in collision with non‐melanoma skin cancers are reviewed. Additionally, the role of immunosuppression in the development of MCC is considered.
Reductions of budgets, staffing, and programs among local health departments: results from NACCHO's economic surveillance surveys, 2009-2013.

OBJECTIVES To provide an overview of budget cuts, job losses, and program reductions among local health departments (LHDs) and to examine the association between LHD infrastructure characteristics and the likelihood of budget cuts. DESIGN Data from 4 waves of the economic surveillance survey (July-August 2009, September-November 2010, January-February 2012, and January-March 2013) conducted by the National Association of County & City Health Officials were analyzed to assess cuts to budgets, jobs, and programs since 2009. Data from the 2013 National Profile of Local Health Departments survey were used to assess the infrastructural characteristics associated with budget cuts. RESULTS When asked in early 2013, more than a quarter of LHDs (26.9%) reported a reduced budget, continuing the trend of a substantial proportion of LHDs experiencing financial hardship in recent years. The percentages of LHDs that made cuts to programmatic areas fluctuated from year to year but have never been lower than 40%. Maternal and child health services were among areas most often cut during all 4 time points of the survey. Governance type, total expenditures, and percentage of revenues from local sources were significantly associated with LHD budget cuts. CONCLUSIONS Cuts in LHD budgets, staff, and activities have been widespread for a period that lasted long after the official end of the Great Recession. There is a great need for substantive and consistent funding to ensure the retention of the workforce and the delivery of essential public health services.