Miracle-dz/UniFAR-FTUs huggingface dataset:
Cause Related Marketing and Customer Value: The Role of Service Quality
and Perceived Risk as Mediators

The present research paper is an attempt to understand the role of mediating variables in the relationship of cause related marketing and customer Value. Based on the literature review, the role of service quality and perceived risk as mediators has been analysed in depth. The data for the study has been collected from mobile subscribers of the select telecom companies that were running cause campaigns. The results of the research showed higher total effect than direct effect, which signalled the role of mediators in the relationship of cause related marketing and customer value. Furthermore it is evident from the analysis that service quality has a direct and significant impact on the relationship of Cause related marketing and customer value, as compared to the perceived risk. This research study emphasizes the role of Cause Related Marketing in enhancing customer value via service quality.
Preinjury family environment as a determinant of recovery from traumatic brain injuries in school-age children

Previous studies of childhood traumatic brain injury (TBI) have emphasized injury-related variables rather than environmental factors as predictors of recovery. We addressed this concern using data collected during a prospective study of children with either TBI or orthopedic injuries (OI) and their families. Participants included 53 children with severe TBI, 56 with moderate TBI, and 80 with OI, all from 6 to 12 years of age at the time of injury. Measures of the preinjury family environment were collected shortly after the injury (baseline). Child cognitive and behavioral outcomes were assessed at baseline and at 6- and 12-month follow-ups. Individual growth curve analyses showed that measures of the preinjury family environment consistently predicted both the level of cognitive and behavioral functioning at 12 months postinjury and the rate of intraindividual change during the 12-month follow-up period, even after taking into account group membership and injury severity. In some cases, the preinjury family environment was a significant moderator of the effect of TBI, buffering its impact in high-functioning families and exacerbating it in low-functioning families. Thus, preinjury environmental factors predict recovery following TBI in children, even after accounting for injury-related variables. (JINS, 1997, 3, 617–630.)
Hemorrhagic Shock-induced Endothelial Cell Activation in a Spontaneous Breathing and a Mechanical Ventilation Hemorrhagic Shock Model Is Induced by a Proinflammatory Response and Not by Hypoxia

Introduction: The interaction between neutrophils and activated endothelium is essential for the development of multiple organ dysfunction in patients with hemorrhagic shock (HS). Mechanical ventilation frequently is used in patients with HS. The authors sought to investigate the consequences of mechanical ventilation of mice subjected to HS on microvascular endothelial activation in the lung and kidney. Methods: Anesthetized wild type C57BL/6 male mice were subjected to controlled hemorrhage; subgroups of mice were mechanically ventilated during the HS insult. To study the effect of acute hypoxia on the mice, the animals were housed in hypoxic cages. Gene expression levels was assessed by quantitative real-time polymerase chain reaction. Protein expression was assessed by immunohistochemistry and enzyme-linked immunosorbent assay. Results: Ninety minutes after the shock induction, a vascular bed-specific, heterogeneous proinflammatory endothelial activation represented by E-selectin, vascular cell adhesion molecule 1, and intercellular adhesion molecule 1 expression was seen in kidney and lung. No differences in adhesion molecules between the spontaneously breathing and mechanically ventilated mice were found. Concentrations of the proinflammatory cytokines chemokine (C-X-C motif) ligand 1 (11.0-fold) and interleukin-6 (21.7-fold) were increased after 90 min of HS. Two hours of 6% oxygen did not induce the expression of E-selectin, vascular cell adhesion molecule 1, and intercellular adhesion molecule 1 in the kidneys and the lung. Conclusions: Hemorrhagic shock leads to an early and reversible proinflammatory endothelial activation in kidney and lung. HS-induced endothelial activation is not changed by mechanical ventilation during the shock phase. Hypoxia alone does not lead to endothelial activation. The observed proinflammatory endothelial activation is mostly ischemia- or reperfusion-dependent and not related to hypoxia.
MOLECULAR POPULATION GENETICS AND EVOLUTION

Will reading habit influence your life? Many say yes. Reading molecular population genetics and evolution is a good habit; you can develop this habit to be such interesting way. Yeah, reading habit will not only make you have any favourite activity. It will be one of guidance of your life. When reading has become a habit, you will not make it as disturbing activities or as boring activity. You can gain many benefits and importances of reading.
Assessing Short-Statured Children for Growth Hormone Deficiency

Aim: To optimize the workup of short-statured children by defining the most appropriate tools for diagnosing growth hormone (GH) deficiency. Methods: Patients were assigned to prepubertal (n = 113) or pubertal (n = 112, including 25 boys primed with testosterone) age groups. Mean plasma GH concentration during sleep, GH peak after provocative test, and insulin-like growth factor I (IGF-I) were measured in a single evaluation. Results: The mean GH concentration during sleep was more often normal (n = 155) than the GH peak after provocative tests (n = 105) or the IGF-I concentration (n = 88). Prepubertal patients with a normal body mass index (BMI) had mean GH concentrations during sleep that correlated positively with height, growth rate, GH peak after provocative tests, and IGF-I (p < 0.0005 for all) and negatively with the difference between target and patient heights (p = 0.01) and BMI (p < 0.05). Pubertal patients with a normal BMI had a mean GH concentration during sleep that correlated positively with GH after provocative tests (p < 0.0001) and IGF-I (p < 0.005). Mean GH concentration during sleep and IGF-I concentration for boys primed with testosterone were more often normal (n = 23) than the GH peak after provocative tests (n = 14). All 9 patients with pituitary stalk interruption had low IGF-I concentrations; 1 patient had a normal GH peak after provocative test, and 2 patients had normal mean GH concentrations during sleep. Conclusions: Measuring the GH concentration during sleep and priming boys with pubertal delay can help to exclude idiopathic GH deficiency. Magnetic resonance imaging is needed to exclude anatomic abnormalities when GH and/or IGF-I concentrations are low.
Late spontaneous rupture of the extensor pollicis longus tendon after corticosteroid injection for flexor tenosynovitis.

INTRODUCTION Spontaneous rupture of the extensor pollicis longus (EPL) tendon has been reported after trauma, rheumatoid arthritis and sports. Rupture may also occur as a consequence of the use of anabolic steroids for recreational purposes, or systemic steroids for the treatment of a variety of medical conditions. CASE REPORT We present a case report of a woman affected with a spontaneous EPL tendon rupture resulted 14 months after a corticosteroid injection for flexor tenosynovitis, "trigger finger," of the thumb. The edges of the tendon were debrided and sutured using figure of eight stitch and a running locked stitch. In addition multiple specimens were sent to Pathology. DISCUSSION Duplay in 1876 described spontaneous rupture as a problem of mechanical and pressure phenomena. Another cause of EPL rupture is related to the development and persistence of inflammatory processes seen in patients with medical illnesses such as rheumatoid arthritis. There have been no reports in the literature to date of spontaneous EPL tendon rupture in the late period after steroid injection. Tendon ruptures in the hand usually occur one or two weeks after a corticosteroid injection, and the affected tendons are usually in neighbouring areas.
Qualitative Methods Used in the Assessment of Engineering Education

This article clarifies key concepts that undergird qualitative research, which is being used increasingly as engineering educators improve classrooms, programs, and institutions. The paper compares quantitative and qualitative research, describes some qualitative data collection strategies used in engineering education, addresses methods for establishing trustworthiness, and discusses strategies for analyzing qualitative data. Also included are illustrative examples of recent engineering education research that features qualitative data analysis and mixed‐method (quantitative and qualitative) approaches.
Personality, Preventive Health Behaviour and Comparative Optimism about Health Problems

The aim was to test a model whereby personality influences preventive health behaviour which in turn influences comparative optimism about possible future health problems. Students (N 5 150) completed measures of personality (five-factor), preventive health behaviour and comparative optimism. The model was tested using structural equation modelling with observed variables. In the final model, agreeableness and conscientiousness had positive main effects and an interactive effect upon preventive health behaviour. Preventive health behaviour had a positive effect upon comparative optimism. In addition, extraversion had a direct positive effect (not mediated by preventive health behaviour) upon comparative optimism. It is speculated that agreeableness and conscientiousness combine to produce a general regard for social convention that is conducive to healthier behaviour. The effect of extraversion is explicable in terms of positive affectivity.
Programmed Cell Death in Amyotrophic Lateral Sclerosis: a Mechanism of Pathogenic and Therapeutic Importance

BackgroundAmyotrophic lateral sclerosis (ALS) is a fatal paralytic disease of adulthood. Mounting evidence indicates that molecular components of the programmed cell death (PCD) machinery are implicated in the demise of motor neurons in this illness. PCD, rather than being passive, is an active mechanism of cell death tightly regulated by multiple molecular pathways. Review SummaryThus far, little is known about the etiology and the pathogenesis of ALS. However, several studies support the view that PCD is instrumental in ALS neurodegenerative process. Data from postmortem ALS specimens and from experimental models of ALS show that some dying motor neurons exhibit features reminiscent of apoptosis, a prominent morphologic form of PCD. In addition, many key molecular components of the PCD machinery are activated in ALS spinal cords. Supporting the significance of these alterations, genetic and pharmacological interventions aimed at mitigating these changes prolong survival and attenuate neurodegeneration in a mouse model of ALS. ConclusionThe morphologic evidence of PCD in ALS remains an equivocal. However, the molecular evidence of PCD involvement in ALS is compelling. Moreover, preclinical studies in mice demonstrate the beneficial effects of targeting PCD on ALS-like neurodegeneration. The neurologist needs to be familiar with the concept of PCD and the potential significance of targeting PCD as neuroprotective strategies for ALS.
PENGARUH PROFITABILITAS, LIKUIDITAS, DAN CAPITAL INTENSITY TERHADAP PENGHINDARAN PAJAK (TAX AVOIDANCE)

Adanya perbedaan kepentingan antara Pemerintah dengan Wajib Pajak menimbulkan tindakan penghindaran pajak ( tax avoidance) oleh Wajib Pajak dalam bentuk memanfaatkan celah Undang-Undang Perpajakan. Penelitian ini bertujuan untuk mengetahui seberapa besar pengatruh profitabilitas, likuiditas dan capital intensity terhadap penghindaran pajak ( tax avoidance ) pada perusahaan sub sektor manufaktur consumer goods yang terdaftar di Bursa Efek Indonesia periode 2013-2016. Penelitian ini menggunakan kriteria purposive sampling dengan metode analisis data panel. Berdasarkan data penlitian diperoleh hasil bahwa profitabilitas berpengaruh negarif terhadap penghindaran pajak pada tingkat signifikan α1%, likuiditas berpengaruh positif pada tingkat signifikan α10% dan capital intensity berpengaruh negatif pada tingkat
Segment Routing Green Spine Switch Management System for DCN

Abstract It is without a doubt that the data center is the core of most IT industries, providing services to billions of users today. Furthermore, due to the exponential increase of information and services from datacenters, it is projected that a 14.1 zeta bits of bandwidth would be needed to meet the current demands of data by the end of 2020 in USA data centers alone. This requires a tremendous amount of energy to run those data centers. To reduce the energy consumption of a data center, this thesis approaches this problem by utilizing Segment Routing and Traffic Engineering to have an efficient the bandwidth usage. The proposed approach makes it possible to deactivate spine switches and links on the data center networks, which results in energy savings. The experimental results yielded up approximately 78% energy savings, whilst maintaining an average similar traffic performance.
Optimal designs for estimating penetrance of rare mutations of a disease‐susceptibility gene

Many clinical decisions require accurate estimates of disease risks associated with mutations of known disease‐susceptibility genes. Such risk estimation is difficult when the mutations are rare. We used computer simulations to compare the performance of estimates obtained from two types of designs based on family data. In the first (clinic‐based designs), families are ascertained because they meet certain criteria concerning multiple disease occurrences among family members. In the second (population‐based designs), families are sampled through a population‐based registry of affected individuals called probands, with oversampling of probands whose families are more likely to segregate mutations. We generated family structures, genotypes, and phenotypes using models that reflect the frequencies and penetrances of mutations of the BRCA1/2 genes. We studied the effects of risk heterogeneity due to unmeasured, shared risk factors by including risk variation due to unmeasured genotypes of another gene. The simulations were chosen to mimic the ascertainment and selection processes commonly used in the two types of designs. We found that penetrance estimates from both designs are nearly unbiased in the absence of unmeasured shared risk factors, but are biased upward in the presence of such factors. The bias increases with increasing variation in risks across genotypes of the second gene. However, it is small compared to the standard error of the estimates. Standard errors from population‐based designs are roughly twice those from clinic‐based designs with the same number of families. Using the root‐mean‐square error as a measure of performance, we found that in all instances, the clinic‐based designs gave more accurate estimates than did the population‐based designs with the same numbers of families. Rough variance calculations suggest that clinic‐based designs give more accurate estimates because they include more identified mutation carriers. Genet Epidemiol 24:173–180, 2003. © 2003 Wiley‐Liss, Inc.
Ultra Compact Inline  ${\rm E}$-Plane Waveguide Extracted Pole Bandpass Filters

This letter presents an ultra compact extracted pole E-plane filter. The proposed structure can achieve up to 65% size reduction in comparison with a standard extracted pole filter designed at 9.5 GHz centre frequency with a 3% fractional bandwidth. The filter has been fabricated and tested using E-plane waveguide technology. Measurements on a fabricated filter confirm the accuracy of the design method.
Embryotoxicity evaluation of iron oxide Fe2O3 on land snails: Helix aspersa

In order to evaluate an ecotoxicological approach to assessing toxicological effects caused by iron oxide powder (Fe2O3) nanoparticles, we conducted a bioassay with helix as a biological model since the species is considered bioaccumulator and bioindicator of pollution. In this study, we evaluated the toxicity of Fe2O3 nanoparticles on the embryonic stage of Helix aspersa with different concentrations (1.25mg/ml, 1.5mg/ml, and 2mg/ml). Results reveal a deformation of the egg membrane and accumulation of this molecule at the back of the egg. We have also noted a low rate of hatching in 12 day, the mortality rate is found to be high at the highest concentration of Fe2O3. This bioassay highlights the toxicity of Fe2O3 nanoparticles on eggs of land snail: Helix aspersa.
Prevention of Inhalational Anthrax in the U.S. Outbreak

The anthrax outbreak in the United States in fall 2001 resulted from the intentional dissemination of Bacillus anthracis spores ([1][1]). In response to the outbreak, public health authorities recommended that some groups of individuals undergo a 60-day regimen of antimicrobial prophylaxis (AP) ([2
ROLE OF TALENT MANAGEMENT PROGRAMMES ON EMPLOYEE PERFORMANCE IN PROFESSIONAL CONSULTANCY SERVICES FIRMS IN KENYA

Purpose: The purpose of this study was to establish the influence of talent management programmes on employee performance in professional consultancy services firms with focus on Deloitte. Methodology: Descriptive study design was applied. The population targeted the 218 employees at Deloitte East Africa that were stationed in Nairobi. Stratified random sampling was applied to select a sample of 141. A questionnaire was utilized to collect primary data. Statistical Package for the Social Sciences (SPSS) was used in analysis and descriptive, correlation and regressions analysis were conducted. Results: The study results showed that talent acquisition was a significant positive predictor of employee performance. Study findings also established that talent development was a significant positive predictor of employee performance. Moreover, talent retention had a significant positive effect on employee performance. Unique Contribution to Theory, Practice and Policy: The study recommended that Deloitte East Africa should ensure that it has enough digital presence to ensure that they forge connections with candidates and strengthen the employment brand. Deloitte East Africa should have a director of talent and development whose responsibilities should be to lead the design, implementation, and evaluation of talent development and management programs. Lastly, since all employees are different with unique goals and desires, Deloitte East Africa should have unique talent retention practices that will appeal to the diverse workforce.
Endoscopically Harvested Stem Cells: A Putative Method in Future Autotransplantation

OBJECTIVE:The discovery of stem cells in the adult human brain and developing stem cell technology open a possible future scenario of autotransplantation, where stem cells are harvested from the patient and propagated in vitro before they are used as transplants. The objectives of this study were: 1) to investigate the feasibility of harvesting tissue containing neural stem cells by endoscopy; 2) to study the possibility of propagating and multiplying stem cells from this tissue efficiently in vitro; and 3) to examine whether the stem cells differentiate into functional neurons. METHODS:In 13 patients with hydrocephalus undergoing routine neurosurgical procedures, we used an endoscope and a 3-mm biopsy forceps (Medtronic) to harvest the small piece of the ventricular wall that is detached by the introduction of the endoscope. Cells were cultured as neurospheres, and after induced differentiation, they were investigated with immunocytochemistry and whole-cell patch-clamp recordings. All cells characterized were propagated under strict clonal conditions. RESULTS:We found it uncomplicated to harvest the part of the lateral ventricular wall that compares with the inner lumen of the endoscope. Single cells, isolated and cultivated in vitro, multiplied to form neurospheres in a serum-free environment. A single stem cell had the potential to give rise to approximately 9 × 105 new cells after two passages. The total number of cells produced from a single biopsy was already, after the second passage, far beyond the number required in, for instance, Parkinson's disease. Within 1 week of induced differentiation, cells expressing markers for neurons (β-III-tubulin or NeuN), oligodendrocytes (RIP or O4), and astrocytes (glial fibrillary acidic protein) appeared. After 3 weeks, cells with a neuronal phenotype showed a firing pattern distinctive of mature neurons, including repetitive, short-lasting, and overshooting action potentials that were blocked by inhibiting voltage-dependent Na+-channels with tetrodotoxin. CONCLUSION:These results indicate that it may be feasible to produce neural tissue for autotransplantation from endoscopically harvested stem cells, but further work is needed in refining culture protocols to control phenotype fate.
Improving the postnatal outcomes of new mothers.

BACKGROUND Postnatal depression persists worldwide as a troubling issue for many new mothers and their families. The practice of early discharge within 72 hours after birth from maternity hospitals in Australia requires community-based care of new mothers, typically provided by community midwives initially, and then by maternal and child health nurses (MCHN). This latter workforce encounters the onset of distress/depression in vulnerable women and is expected to manage their care, but their training does not equip sufficiently them to do this. AIMS The aim of the study was to evaluate the effectiveness of brief training for MCHN in early detection and effective management of mildly distressed new mothers. METHODS A controlled comparative longitudinal study was carried out with a group of first-time mothers recruited through antenatal clinics at four major hospitals in a large Australian city. Forty MCHN were allocated to the intervention group. Those in the intervention group received training in the identification and management of distressed mothers. Intervention group nurses also had access to a liaison psychiatric network for consultation and referrals. Other nurses were allocated to the control group, which provided standard management services to new mothers in their catchment areas. Mothers' outcomes in psychological and psychosocial functioning were assessed; comparing those cared for by the nurses who had received the intervention with those cared for by standard practices. Mothers' satisfaction with the maternal and child health nurse services was also assessed. RESULTS Levels of distress peaked in early pregnancy in both groups and reduced over the study period. Rates and group levels of psychological distress and psychosocial functioning did not differ over time between mothers receiving care from the enhanced trained nurses and those receiving standard care. Differential group findings were apparent in attrition, with the more distressed mothers withdrawing from the control group and the less distressed withdrawing from the intervention group. Satisfaction with maternal and child health nurse services was high in both groups. Limitations of the study included events occurring while the study was in progress, such as staffing upheaval and unrest following the introduction of compulsory competitive tendering requirements, heavy workloads and the concurrent introduction of computerized case records that required the rapid familiarization with computer usage. CONCLUSIONS Findings indicate that the extra training of MCHN did not substantially assist in the detection and management of postnatal distress in these new mothers. Unexpected ecological conditions of workforce disruption and extra workloads may have mitigated against the success of the programme. Limitations of the study are examined and the implications for future research are discussed.