Miracle-dz/UniFAR-FTUs huggingface dataset:
Anaphylactic shock-induced ischemic proctocolitis following bee stings: first case report

for hematochezia following resuscitation from a hypotensive shock. The history revealed that while working outdoors, the patient had been attacked by a swarm of bees and received multiple stings, rendering him unconscious. Following initial recovery at the local hospital, he developed hematochezia and was referred to us. On examination at admission, the patient was alert and not pale, and his vital signs were stable. He denied any previous allergic history related to drugs or other substances, and he was not taking any medication. There was no notable family history. Pain and tenderness were elicited in the periumbilical region but without rebound tenderness. Digital rectal examination revealed bloody and mucoid discharge. The initial laboratory results showed leukocytosis and mild elevation of serum aminotransferases without anemia. Abdominopelvic computed tomography (CT) disclosed edematous wall thickening in the rectosigmoid and cecal regions. Electrocardiography did not show any sign of cardiac arrhythmia. On sigmoidoscopy, the rectal mucosa was hemorrhagic and greatly swollen with narrowing of the lumen, whitish exudates, and intermittent, deep ulcerations (●" Fig. 1a). This presentation persisted as the scopewas advanced and then relatively normal mucosa was seen at 25 cm from the anal vergewith a sharply distinct margin (●" Fig. 1b). Total colonoscopy carried out the next day revealed cecal pathology with similar findings (●" Fig. 1c). Following administration of empirical antibiotics, bowel rest, and copious intravenous hydration, the abdominal pain subsided and the hematochezia ceased. The patient resumed his normal diet 11 days after admission. Pathologic examination verified the diagnosis of ischemic colitis. Followup total colonoscopy before discharge revealed much improvement (●" Fig. 1d– f), and a later endoscopic review examination revealed minimal changes in the colonic mucosa with no evidence of stricture or other deformities. Ischemic colitis is the most commonmanifestation of mesenteric ischemia [1], and a few cases of acute ischemic colitis of unusual etiology have been reported [2– 5]. Our patient’s young age and otherwise apparently healthy constitution with no notable medical history are suggestive of low probability of atherosclerotic change and susceptibility to any kind of bowel ischemia. Our patient therefore exemplifies a rare instance of anaphylactic shock caused by bee stings leading to ischemic colitis, and is the only case of its kind to be reported to date.
Injection of microfilariae induces resistance to Brugia malayi infection in ferrets and accelerates development of lymphostatic disease

Summary Ferrets injected intravenously with living microfilariae or cutaneously with microfilariae followed by intravenous injection developed partial resistance to a challenge infection as measured by recovery of adult filariae from lymphatics. Following a challenge infection, the ferrets injected with microfilariae developed lymphatic pathology characteristic of a chronic infection or that observed following multiple infections. There was disruption of lymphatic drainage of the infected limb and lymphoedema. The results suggest that immune responses to antigens of microfilariae, presumably antigens shared with other developmental stages, effected both increased resistance and enhanced lymphatic pathology.
An inside view: credibility in Wikipedia from the perspective of editors

Introduction. The question of credibility in participatory information environments, particularly Wikipedia, has been much debated. This paper investigates how editors on Swedish Wikipedia consider credibility when they edit and read Wikipedia articles. Method. The study builds on interviews with 11 editors on Swedish Wikipedia, supported by a document analysis of policies on Swedish Wikipedia. Analysis. The interview transcripts have been coded qualitatively according to the participants' use of Wikipedia and what they take into consideration in making credibility assessments. Results. The participants use Wikipedia for purposes where it is not vital that the information is correct. Their credibility assessments are mainly based on authorship, verifiability, and the editing history of an article. Conclusions. The situations and purposes for which the editors use Wikipedia are similar to other user groups, but they draw on their knowledge as members of the network of practice of wikipedians to make credibility assessments, including knowledge of certain editors and of the MediaWiki architecture. Their assessments have more similarities to those used in traditional media than to assessments springing from the wisdom of crowds.
Dental Health and Access to Dental Care for Ethnic Minorities in Sweden

Objective. To describe access to dental care in a population-based sample of foreignborn Swedish residents in relation to dental health. Design. The study was based on data from the Immigrant Survey of Living Conditions in four minority study groups consisting of a total of 1,898 Swedish residents born in Poland, Chile, Turkey and Iran aged 2760. An age-matched study group of 2,477 Swedish-born residents from the Survey of Living Conditions of 1996 was added as a comparison group. The study also included 2,228 children aged 315 years in the minority households and 2,892 children in the households of the Swedish-born study group. Results. The risk of poor dental health was higher in all four minority study groups than for the Swedish-born study group after adjusting for socio-economic variables. In the adult minority study groups the adjusted odds ratios (ORs) for having prostheses and problems with chewing was 6.3 (4.39.1) and 2.7 (1.84.3), respectively, for the Polish-born, 4.8 (3.37.1) and 3.2 (2.14.9) for the Chilean-born, 4.6 (3.16.9) and 4.8 (3.67.2) for the Turkish-born, and 2.7 (1.54.8) and 6.5 (4.110.3) for the Iranian-born compared with the Swedish-born. In the child study group all four minority groups had an increased risk of caries ranging from OR 1.6 (1.32.1) in the Chilean group to 2.5 (2.03.0) in the Turkish group compared with the children with Swedish-born parents. The adults in all four minority study groups more often lacked regular treatment by a dentist than Swedish-born residents. The OR for not having been treated by a dentist during the 2 years preceding the interview ranged from 1.9 (1.42.6) in the Polish-born study group to 3.0 (2.34.0) in the Chilean-born study group after adjustment for socio-economic factors and general health. Conclusion. This study demonstrates that adults in minority populations in Sweden use less dental care despite having greater needs of dental treatment than the majority population. This inequity calls for action in health policy and preventive dental health programmes.
The Role of the Renin‐Angiotensin System in Mediation of Adrenal Catecholamine Secretion in the Cat Induced by Intrarenal β‐Adrenergic Stimulation

Isoproterenol infusion (0.1 μ/kg per min) into the renal artery of the cat induced an increase in plasma renin concentration (PRC) from 14.3 ± 5.7 (mean ± SE) ng angiotensin I/ml per hr to 56.8 ± 7.7 after 70 minutes {P < 0.05) and an increase in catecholamine secretion rate from 38.7 ± 6.0 ng/kg per 10 min to 180.0 ± 40.0 after 70 minutes (P< 0.001). Intravenous infusion of the same dose of isoproterenol had no significant effect on adrenomedullary catecholamine secretion rate. Isoproterenol induced preferential norepinephrine release: the ratio of norepinephrine to epinephrine secretion changed from 11.5:23.7 during the control period to 130.0:40.1 70 minutes after the start of isoproterenol administration. Intrarenal infusion of propranolol (3.0 mg/kg per min) inhibited renal renin release and adrenal catecholamine secretion in response to intrarenal isoproterenol. Intravenous infusion (0.4 Mg/kg P e r m in) °fan angiotensin II antagonist [Sar Ileu8]angiotensin II abolished the catecholamine response to intrarenal isoproterenol infusion. It is suggested that intrarenal isoproterenol infusion stimulates renal renin release and angiotensin production which, in turn, stimulates a preferential secretion of adrenomedullary norepinephrine. Circ Res 47: 835-839, 1980
Imaging the lungs in asthmatic patients by using hyperpolarized helium-3 magnetic resonance: assessment of response to methacholine and exercise challenge.

BACKGROUND Imaging of gas distribution in the lungs of patients with asthma has been restricted because of the lack of a suitable gaseous contrast agent. Hyperpolarized helium-3 (HHe3) provides a new technique for magnetic resonance imaging of lung diseases. OBJECTIVE We sought to investigate the use of HHe3 gas to image the lungs of patients with moderate or severe asthma and to assess changes in gas distribution after methacholine and exercise challenge. METHODS Magnetic resonance imaging was performed in asthmatic patients immediately after inhalation of HHe3 gas. In addition, images were obtained before and after methacholine challenge and a standard exercise test. RESULTS Areas of the lung with no signal or sharply reduced HHe3 signal (ventilation defects) are common in patients with asthma, and the number of defects was inversely related to the percent predicted FEV(1) (r = 0.71, P <.002). After methacholine challenge (n = 3), the number of defects increased. Similarly, imaging of the lungs after exercise (n = 6) showed increased ventilation defects in parallel with decreases in FEV(1). The increase in defects after challenge in these 9 asthmatic patients was significant both for the number (P <.02) and extent (P <.02) of the defects. The variability and speed of changes in ventilation and the complete lack of signal in many areas is in keeping with a model in which the defects result from airway closure. CONCLUSION HHe3 magnetic resonance provides a new technique for imaging the distribution of inhaled air in the lungs. The technique is suitable for following responses to treatment of asthma and changes after methacholine or exercise challenge.
Spin density wave order, topological order, and Fermi surface reconstruction

In the conventional theory of density wave ordering in metals, the onset of spin density wave (SDW) order coincides with the reconstruction of the Fermi surfaces into small ``pockets. '' We present models which display this transition, while also displaying an alternative route between these phases via an intermediate phase with topological order, no broken symmetry, and pocket Fermi surfaces. The models involve coupling emergent gauge fields to a fractionalized SDW order, but retain the canonical electron operator in the underlying Hamiltonian. We establish an intimate connection between the suppression of certain defects in the SDW order and the presence of Fermi surface sizes distinct from the Luttinger value in Fermi liquids. We discuss the relevance of such models to the physics of the hole-doped cuprates near optimal doping.
Formation and Evolution of the Centennial Unconformity-Related Uranium Deposit in the South-Central Athabasca Basin, Canada

The Centennial U deposit is situated in the south-central Athabasca Basin (Canada) and straddles the unconformity between early Paleoproterozoic to Archean metasedimentary and metavolcanic rocks and granitoids, and the clastic sediments of the Paleoproterozoic Athabasca Group. Although it has most characteristics of an unconformity-related uranium deposit, the Centennial deposit is atypical in that it is not directly associated with an electromagnetic conductor (there is a paucity of graphite in the basement) or with a major reverse fault zone; it is distal from a major fluid conduit (ca. 300 to 400 m from the Dufferin Lake Fault), has low Ni, Cu, Co, Zn, and Pb contents, and contains an unusually large amount (up to 5%) of secondary uranyl minerals. Additionally, a network of diabase dikes and sills is observed at Centennial, seemingly intruding the main U mineralization of massive uraninite, based on the relatively sharp contacts between the diabase dike and the high-grade U mineralization. The pre-U alteration assemblage at Centennial includes kaolinite, illite, and sudoite, which have been formed by fluids with isotopic and chemical compositions that are comparable with those from other sandstone-hosted unconformity-type U deposits in the Athabasca Basin. Pre-U illite-related fluids have δ 18O of ca. 3‰ and δ D of ca. −40‰, whereas pre-U chlorite-related fluids have δ 18O between 1.7 and 4.3‰ and δ D between −18 and 1‰. Laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) U/Pb dating of the various U phases indicates that initial mineralization, represented by disseminated uraninite found directly to the north-northeast of the Centennial deposit, occurred at ca. 1.6 Ga. The main U mineralization, represented by massive and strongly altered uraninite, followed at an unknown time. A minor (<5%) unaltered uraninite formed from the local remobilization of the main massive uraninite at ca. 380 Ma. The main uranyl mineral, uranophane, formed last, at ca. 2 Ma. The recurrence of local U remobilization might have been facilitated by the persisting high permeability of the sandstones in the area due to the nearby Dufferin Lake Fault and to the emplacement of the diabase dikes. The usefulness of Pb isotopes for exploration is demonstrated at the Centennial deposit, with strongly radiogenic Pb isotope signatures close to the deposit and a common Pb signature observed at a distance of a few km from the deposit.
Evolution of regional scientific collaboration networks: China-Europe emerging collaborations on nano-science

This study analyses the dynamics of regional scientific collaboration networks between Chinese and European regions on the emerging nano-science field. Using data on the co-author publications between Chinese and European nano-scientists for the period 1990-2011, the results enable us to identify the evolutionary and active collaboration networks between China and Europe. The driving forces for engaging cross-border regional collaboration networks are identified between a new global science polar and a traditional scientific superpower. This analysis suggests that the rapid and uneven growth of scientific collaboration networks between China and European Union membership nation's evolutes, which resulting from multiple factors. Implications for promoting global-regional collaborations among scientists' communities are discussed.
Induction of Adaptive Response by Low-Dose Radiation in RIF Cells Transfected with Hspb1 (Hsp25) or Inducible Hspa (Hsp70)

Abstract Lee, Y-J., Park, G-H. , Cho, H-N. , Cho, C-K. , Park, Y-M. , Lee, S-J. and Lee, Y-S. Induction of Adaptive Response by Low-Dose Radiation in RIF Cells Transfected with Hspb1 (Hsp25) or Inducible Hspa (Hsp70). Radiat. Res. 157, 371–377 (2002). An adaptive response results in a reduced effect of a high challenging dose of a stressor after a smaller, inducing dose has been applied a few hours earlier. Radiation-induced fibrosarcoma (RIF) cells did not show an adaptive response, i.e. a reduced effect from a high challenging dose (2 Gy) of a radiation after a priming dose (1 cGy) had been applied 4 or 7 h earlier, but cells of a thermoresistant clone (TR) derived from RIF cells did. Since the expression of inducible Hspa (also known as Hsp70) and Hspb1 (also known as Hsp25) was different in these two cell lines, the role of inducible Hspa and Hspb1 in the adaptive response was examined. When RIF cells were transfected with inducible Hspa or Hspb1, both radioresistance measured by clonogenic assays and a reduction of apoptosis were detected. The adaptive response was also acquired by these two cell lines. The inducible Hspa transfectant showed a more pronounced adaptive response than the Hspb1 transfectant. Based on these results, it appears that inducible Hspa and Hspb1 are at least partly responsible for the induction of the adaptive response in these cells. Moreover, when inducible Hspa or Hspb1 was transfected into RIF cells, co-regulation of the two genes was detected. Heat-shock factor (Hsf) was found to be at least partially responsible for the induction of the adaptive response in these cells.
Relationship between delayed and spatially extended dynamical systems.

The interpretation of delayed dynamical systems (DDS) in terms of a suitable spatiotemporal dynamics is put on a rigorous ground by deriving amplitude equations in the vicinity of a Hopf bifurcation. We show that comoving Lyapunov exponents can be defined and computed in a DDS. From the propagation of localized infinitesimal disturbances in DDS, we show the existence of convective type instabilities. Moreover, a widely studied class of DDS is mapped onto an evolution rule for a spatial system with drift and diffusion.
Effect of a lactobacillus product administration on the anaerobic intestinal flora of aged adults.

Estimations were performed on the numbers of Clostridium perfringens in 1-ml samples of fecal specimens collected from 30 healthy aged adults. These measurements were repeated 15 times for each individual during a 16-week period. Most of the fecal samples proved to consistently contain more than 105 C. perfringens cells and the majority of aged adults were observed to carry over 106 cells of this organism on more than eight testing occasions. Few adults were revealed to carry over 107 cells with fairly strong α-toxigenicities without any clinical symptoms. An attempt to decrease the numbers of organisms present by continued drinking of a commercial product containing live lactobacilli resulted in failure, whilst a gradual increase in the numbers of lactobacilli and a decrease in the numbers of Bacteroides were observed. Most infants when examined for the numbers of C. perfringens in a 1-ml portion of their fecal specimens, showed less than 102 cells of this organism and when given the Lactobacillus preparation per os exhibited a rapid increase in the numbers of lactobacilli in their intestinal contents.
Physical activity among Spanish adolescents: Relationship with their relatives' physical activity – The AVENA Study

Abstract Identifying factors related to physical activity levels in young people is important for a more efficient health promotion. The aims of this study were to assess physical activity levels in a national sample of urban Spanish adolescents, and to examine the association between significant others' physical activity (father, mother, brother, sister, and close friends) and that of the adolescents. The present study comprised 2260 adolescents (1157 boys, 1103 girls) aged 13.0–18.5 years participating in the AVENA Study. Both the adolescents' physical activity and that of their relatives and close friends was assessed by questionnaire. The odds of being active were higher in boys than girls (odds ratio = 2.79, 95% confidence interval = 2.34–3.33) and tended to decrease across age groups in both boys and girls. Father's and older brother's physical activity was associated with boys' physical activity, while that of any significant other was associated with girls' physical activity. When both parents reported being active, boys had nearly two times higher odds of being active and girls had nearly three times higher odds of being active. The physical activity levels of Spanish adolescents are in line with those previously reported. Physical activity levels in girls are strongly related to the physical activity of any significant other, whereas physical activity levels in boys are only related to their male relatives' physical activity.
Epidemiology of acute spinal cord injuries in the Groote Schuur Hospital Acute Spinal Cord Injury (GSH ASCI) Unit, Cape Town, South Africa, over the past 11 years.

BACKGROUND Spinal cord injury (SCI) is devastating to both patient and society, with acute management and ongoing care being extremely expensive. Few epidemiological data are available on SCIs in South Africa (SA). OBJECTIVES To identify the epidemiological profile of SCI patients at Groote Schuur Hospital (GSH), Cape Town, SA, and identify seasonal trends and peak periods. As the majority of the injuries are preventable, these data are important to develop prevention strategies. METHODS A retrospective review of prospectively collected data was conducted on all patients admitted to the Acute Spinal Cord Injury (ASCI) Unit at GSH from 1 April 2003 to 31 March 2014. All cases registered on a prospectively maintained database were included in the study. RESULTS The total number of patients admitted to the ASCI Unit was 2,042, with an average of 185 admissions per year. The male/female ratio was 5.25:1. The 21-30-year-old age category was the largest, comprising 33.5% of the patients. The most prevalent cause of injury was motor vehicle accidents (44.6%), followed by violence-related injuries (27.2%). Thirty-two point two per cent of patients needed ventilatory support, and 91.5% of mechanically ventilated patients were successfully weaned. December was the busiest month in the unit. In patients in whom neurological deficit was incomplete, the average motor function improvement was 16.0%. CONCLUSIONS Data capturing and analysis of SCIs should be encouraged in SA to guide management and prevention strategies, and to optimise outcomes. This study establishes the ASCI Unit at GSH to be one of the key role players in acute SCI management in SA.
ARID 1 A expression in gastric adenocarcinoma : clinicopathological significance and correlation with DNA mismatch repair status MMR and ARID 1 A in gastric cancer

AIM: To analyze the mismatch repair (MMR) status and the ARID1A expression as well as their clinicopathological significance in gastric adenocarcinomas. METHODS: We examined the expressions of MMR proteins and ARID1A by immunohistochemistry in consecutive 489 primary gastric adenocarcinomas. The results were further correlated with clinicopathological variables. RESULTS: The loss of any MMR protein expression, indicative of MMR deficiency, was observed in 38 cases (7.8%) and was significantly associated with an older age (68.6 ± 9.2 vs 60.4 ± 11.7, P < 0.001), a female sex (55.3% vs 31.3%, P = 0.004), an antral location (44.7% vs 25.7%, P = 0.021), and a differentiated histology (57.9% vs 39.7%, P = 0.023). Abnormal ARID1A expression, including reduced or loss of ARID1A expression, was observed in 109 cases (22.3%) and was significantly correlated with lymphatic invasion (80.7% vs 69.5%, P = 0.022) and lymph node metastasis (83.5% vs 73.7%, P = 0.042). The tumors with abnormal ARID1A expression more frequently indicated MMR deficiency (47.4% vs 20.2%, P < 0.001). A multivariate analysis
Evaluation of Sugar Syrup as a Partial Substitute for Maize in Broilers ’ Ration

A study was conducted to evaluate sugar syrup as a partial substitute for maize on feed consumption, growth rate, feed conversion ratio, carcass yield and economic importance of using sugar syrup in the ration of broilers. Three hundred one day old Hubbard classic chicks were randomly distributed to five treatments each with three replications in CRD with 0, 7, 14, 21, and 28% of maize substituted by sugar syrup for T1, T2, T3, T4, and T5, respectively. The results obtained indicated that there was no significant difference (P>0.05) in DM intake, body weight gain and mortality during the entire growth period. There was significant difference (P<0.05) in feed as well as protein and energy conversion ratio among the treatment groups during the whole growth period. Slaughter weight, eviscerated weight, drumstickthigh weight and percent as well as breast weight and percent showed non significant difference (P>0.05) among treatments. But significant difference (P<0.05) was observed in eviscerated percentage. Abdominal fat weight and percent was greater for T1 and T2 as compared to T4 and T5. Birds in T4 and T5 score higher chicks’ sale to feed cost than T2, T1 and T3. In summary, increasing the substitution level of sugar syrup for maize increases profit. The study highlighted that sugar syrup could substitute maize up to 28% in formulating broilers’ ration without adverse effect on growth performance.