Miracle-dz/UniFAR-FTUs huggingface dataset:
Multicenter Prospective Comparative Study of Robotic Versus Laparoscopic Gastrectomy for Gastric Adenocarcinoma.

OBJECTIVE To compare short-term surgical outcomes including financial cost of robotic and laparoscopic gastrectomy. BACKGROUND Despite a lack of supporting evidence, robotic surgery has been increasingly adopted as a minimally invasive modality for the treatment of gastric cancer because of its assumed technical superiority over conventional laparoscopy. METHODS A prospective, multicenter comparative study was conducted. Patients were matched according to the surgeon, extent of gastric resection, and sex. The primary endpoint was morbidity and mortality. Outcomes were analyzed on an intention-to-treat and per-protocol basis. RESULTS A total of 434 patients were enrolled for treatment with either robotic (n = 223) or laparoscopic (n = 211) gastrectomy for intention-to-treat analysis, and a total of 370 patients (n = 185 per treatment) were compared in per-protocol analysis. Results were similar between both analyses. In per-protocol analysis, both groups showed similar overall complication rates (robotic = 11.9% vs laparoscopic = 10.3%) and major complication rates (robotic = 1.1% vs laparoscopic = 1.1%) with no operative mortality in either group. Patients treated with robotic surgery showed significantly longer operative time (robotic = 221 minutes vs laparoscopic = 178 minutes; P < 0.001) and significantly higher total costs (robotic = US$13,432 vs laparoscopic = US$8090; P < 0.001), compared with those who underwent laparoscopic gastrectomy. No significant differences between groups were noted in estimated blood loss, rates of open conversion, diet build-up, or length of hospital stay. CONCLUSIONS The use of robotic systems is assumed to provide a technically superior operative environment for minimally invasive surgery. However, our analysis of perioperative surgical outcomes indicated that robotic gastrectomy is not superior to laparoscopic gastrectomy. Clinical trials identification: NCT01309256.
Exploring the folding energy landscape of a series of designed consensus tetratricopeptide repeat proteins

Repeat proteins contain short, tandem arrays of simple structural motifs (20−40 aa). These stack together to form nonglobular structures that are stabilized by short-range interactions from residues close in primary sequence. Unlike globular proteins, they have few, if any, long-range nonlocal stabilizing interactions. One ubiquitous repeat is the tetratricopeptide motif (TPR), a 34-aa helix-turn-helix motif. In this article we describe the folding kinetics of a series of 7 designed TPR proteins that are assembled from arraying identical designed consensus repeats (CTPRan). These range from the smallest 2-repeat protein to a large 10-repeat protein (≈350 aa). In particular, we describe how the energy landscape changes with the addition of repeat units. The data reveal that although the CTPRa proteins have low local frustration, their highly symmetric, modular native structure is reflected in their multistate kinetics of unfolding and folding. Moreover, although the initial folding of all CTPRan proteins involves a nucleus with similar solvent accessibility, their subsequent folding to the native structure depends directly on repeat number. This corresponds to an increasingly complex landscape that culminates in CTPRa10 populating a misfolded, off-pathway intermediate. These results extend our current understanding of the malleable folding pathways of repeat proteins and highlight the consequences of adding identical repeats to the energy landscape.
Motivation for corss‐dressing in heterosexual transvestism

The literature concerning the motivation for corss‐dressing in heterosexual transvestism is briefly reviewed. Thirty‐three members of a club estiblished for hetersexual transvestities were interviewed. The sensations they derived fro cross‐dressing and the importance of compulsive and nacissistic aspects in their transvestite behaviour were assessed and compared with those reported by 24 transsexual subjects.
X-linked dominant Charcot-Marie-Tooth disease with connexin 32 ( Cx 32 ) mutations in Koreans

X-linked dominant Charcot-Marie-Tooth disease (CMTX) is an inherited peripheral neuropathy, caused mainly by a mutation of connexin 32 (Cx32 ) gene. We performed a mutation analysis of Cx32 by direct sequencing of the coding sequence, then identified 23 mutations from 28 Korean CMTX families. Nine mutations were not reported previously: Gly5Ser, Ser26fs, Val37Leu, Thr86Ile, Val152fs, Phe153Cys, Asp178X, Ala197Val, and Ile214Asn. The extracellular 2 (EC2) domain of Cx32 protein was the hot spot mutation domain in 44% of Koreans. Transmembrane domain 4 was rarely affected in Koreans (4%), compared with 14% of Europeans. The EC1 and intracellular domain was not affected in Koreans, although they were frequently affected in Europeans. This study revealed that the frequencies of CMTX with Cx32 mutations are specific to different ethnic groups. The frequency of CMTX (5.3%) caused by Cx32 mutation in Koreans is similar to those in Asians but lower than those in Europeans. This study suggests differences between CMTX patients with Cx32 mutations and ethnic background.
Alveolar defects in human skulls.

Abstract The prevalence and intra-oral distribution of dehiscences and fenestrations was determined in 398 19th Century British skulls. The percentage of teeth and skulls with dehiscences and fenestrations decreased with age and over half of the affected skulls, with the exception of the oldest age group, had two or more defects. Dehiscences were consistently observed on the mandibular canines and first premolars and the maxillary canines and first molars. Fenestrations were found most frequently on the maxillary first molars and the mandibular lateral incisors and canines.
Characterization of flow emerging from a stenosis using MRI

MRI ultra‐fast imaging techniques are used to characterize flow emerging from streamlined and abrupt stenoses inside cylindrical channels. Reattachment lengths of the shear boundary to the channel wall are measured using rotating ultra‐fast imaging sequence (RUFIS) in‐flow imaging. Velocity profiles of flow are created using velocity (sine and cosine)‐encoded RUFIS sequences. The sine‐encoded images permit one to identify reverse flow (i.e., eddies) that arise within the region of flow reattachment. The ratios of peak velocities (downstreamhpstream of the stenosis) derived from the cosine‐encoded images are used to identify the transition from the laminar to the turbulent regimen. Based on these experiments, the transition from the laminar to turbulent regimen occurs at a stenotic Reynolds Number of 350, whereas fully developed turbulence occurs at a stenotic Reynolds Number of 2600. These results are compared with the results from invasive studies.
Mencapai Financial Well-being melalui Peran Financial literacy bagi Masyarakat Indonesia

Literasi keuangan (financial literacy) memegang peran kunci dalam pencapaian kemapanan finansial (financial wellbeing). Literasi keuangan akan membantu seseorang untuk memiliki tujuan-tujuan keuangan yang terarah dan runtut berdasarkan skala prioritas. Literasi keuangan akan membantu seseorang untuk mengendalikan cara membelanjakan uang, agar berdasarkan kebutuhan (need) dan bukan keinginan (want). Apabila seseorang telah mampu mengendalikan cara membelanjakan uangnya (spending) dengan bijak, maka kemapuan menyisihkan penghasilan untuk ditabung akan terus tumbuh. Kemampuan untuk menabung secara berkesinambungan akan memungkinkan seseorang untuk menginvestasikan sebagian penghasilannya. Kebiasaan berinvestasi akan memungkinkan seseorang untuk meraih seluruh tujuan keuangannya, yang dikenal dengan kemapanan finansial (financial wellbeing). Namun berdasarkan data financial literacy di Indonesia, ditemukan financial lteracy masyarakat Indonesia masih terkonsentrasi pada produk perbankan. Sementara financial literacy masyarakat Indonesia pada produk pasar modal dan asuransi masih rendah. Bercermin pada data financial lteracy, maka dapat diketahui bahwa pencapaian kemapanan finansial di Indonesia masih menghadapi hambatan yang cukup besar. Perjalanan sosialisasi financial lteracy masih perlu terus dilakukan secara berkesinambungan, agar harapan tercapainya masyarakat Indonesia yang mapan secara finansial dapat tercapai.
Contrast-enhanced CT colonography in recurrent colorectal carcinoma: feasibility of simultaneous evaluation for metastatic disease, local recurrence, and metachronous neoplasia in colorectal carcinoma.

OBJECTIVE Contrast-enhanced CT colonography has the potential to detect local recurrence, metachronous disease, and distant metastases in patients with a history of invasive colorectal cancer. The purpose of our study was to determine whether colonic anastomoses prohibit adequate colonic distention on contrast-enhanced CT colonography and to estimate the performance of contrast-enhanced CT colonography in detecting recurrent colorectal carcinoma. MATERIALS AND METHODS Fifty patients with a history of resected invasive colorectal carcinoma underwent contrast-enhanced CT colonography and colonoscopy. Colonic distention was graded for different colonic segments. Two radiologists evaluated for the presence of local recurrence, metachronous disease, and metastatic disease. Results were compared with colonoscopy, histology, and clinical follow-up. RESULTS Most patients had adequate colonic inflation (37/50, 74%). Eleven of 13 patients with inadequate distention had collapse in the sigmoid colon, usually associated with ileocolic anastomoses. Contrast-enhanced CT colonography detected local recurrences with an accuracy of 94% (95% confidence interval, 83-99%). The accuracy of contrast-enhanced CT colonography for metachronous lesions greater than or equal to 1 cm was 92% (95% confidence interval, 80-98%), but there was only one such lesion, which was missed on initial colonoscopy. Stool, granulation tissue, and inflammation can mimic the CT appearance of local recurrence or metachronous disease and account for false-positive examinations. Contrast-enhanced CT colonography identified five patients with metastatic disease. CONCLUSION Suboptimal sigmoid distention can be seen on contrast-enhanced CT colonography, predominantly in patients with right hemicolectomies. Contrast-enhanced CT colonography is a promising method for detecting local recurrence, metachronous disease, and distant metastases in patients with prior invasive colorectal carcinoma. The technique can also serve as a useful adjunct to colonoscopy by detecting local recurrences or metachronous disease that are endoscopically obscure or by serving as a full structural colonic examination when endoscopy is incomplete.
Blood pressure and risk of stroke in patients with cerebrovascular disease

There is widespread clinical uncertainty about lowering blood pressure in patients with ischaemic cerebrovascular disease. This often manifests as comparatively high thresholds for starting treatment and modest targets in reducing blood pressure. Concern has arisen partly from reports of a J shaped association between blood pressure and recurrent stroke in these patients.1 This relation may, however, be because severe strokes are associated both with a fall in blood pressure2 and independently with a relatively high risk of stroke recurrence, rather than from any adverse effects of low blood pressure itself. If this were true, then people with a history of minor cerebrovascular disease would have direct and continuous relations between usual blood pressure and risk of stroke, as observed in people without cerebrovascular disease.3 Data from …
Rethinking Asset Bubbles: Reflections for the Age of Institutional Investing

Upon surveying a contentious topic that has occasioned much debate, this paper offers reflections on the likelihood that asset booms, bubbles and busts continue posing a threat to financial stability despite financial markets becoming increasingly informationally-efficient, complete, and heavily influenced by sophisticated (presumably rational) investors. Rather than arise from widespread behavioral irrationality as is commonly assumed, this paper suggests procyclical mispricings stand to increasingly reflect institutional frictions — benchmarking, incentive and organizational design pressures — in the rapidly-growing institutional investment industry. These influences may make bubble riding ‘rational,’ or at the very least, discourage institutions from leaning against the wind. Moreover, even in the absence of leverage, systemic risk could increasingly be shaped by large shifts in risk premia owing to the rational herding motivations of institutional investors. To the extent procyclicality owes less to ‘irrational exuberance’ and more to performance evaluation practices, traditional countercyclical policy measures could be of reduced efficacy unless reinforced by reforms to institutional incentives.
Measures to prevent transfusion‐related acute lung injury (TRALI)

H. W. Reesink, J. Lee, A. Keller, P. Dennington, J. Pink, R. Holdsworth, H. Schennach, M. Goldman, T. Petraszko, J. Sun, Y. Meng, K. Qian, V. Rehacek, P. Turek, T. Krusius, E. Juvonen, P. Tiberghien, D. Legrand, G. Semana, J. Y. Muller, J. Bux, A. Reil, C. K. Lin, H. Daly, E. McSweeney, L. Porretti, N. Greppi, P. Rebulla, H. Okazaki, S. A. Sanchez-Guerrero, H. A. Baptista-Gonzalez, C. Martinez-Murillo, A. Guerra-Marquez, H. Rodriguez-Moyado, R. A. Middelburg, J. C. Wiersum-Osselton, A. Brand, C. van Tilburg, D. Dinesh, J. Dagger, P. Dunn, E. Brojer, M. Letowska, K. Maslanka, E. Lachert, M. Uhrynowska, E. Zhiburt, M. Palfi, G. Berlin, B. M. Frey, L. Puig Rovira, E. Muniz-Diaz, E. Castro, C. Chapman, A. Green, E. Massey, N. Win, L. Williamson, C. C. Silliman, D. J. Chaffin, D. R. Ambruso, N. Blumberg, P. Tomasulo, K. J. Land, P. J. Norris, O. C. Illoh, R. J. Davey, R. J. Benjamin, A. F. Eder, L. McLaughlin, S. Kleinman & S. Panzer
The Effect of Green Organizational Culture and Green Innovation in influencing Competitive Advantage and Environmental Performance

The preset study investigated the role of green organizational culture as the antecedent of both green product and process innovation. In addition, the current examination also analyzed the unique contribution of both product and process innovation in prompting organizational competitiveness and environmental performance in Malaysian companies. In doing so, we apply Partial Least Square equation modeling approach. The results of the examination confirm that green product innovation, green process innovation and competitive advantage have positive and significant influenced by green organizational culture. Moreover, the results of PLS-SEM likewise confirm that competitive advantage is positive and significantly influenced by green product innovation and green process innovation. The outcomes further affirm that competitive advantage has positively and significantly impact on environmental performance in Malaysian manufacturing firms.
The effect of corporate governance on the cost of debt capital

Agency theory predicts that corporate governance (CG) and audit quality (AQ) enhance the convergence of interests between shareholders and managers and enable investors and lenders to have better perception on the optimum level of cost of debt capital. However, there is a lack of studies that investigate this issue in the emerging markets, particularly in Malaysia. Therefore, this research is conducted to investigate the relationship between internal monitoring characteristics of board of director and audit committee relating to the size, independence, financial expertise, frequency of meeting, ethnicity and education of directors and ethnicity of chairperson, and AQ as proxies by audit fees, non-audit service fees and industry specialist auditor, as external monitoring on the cost of debt capital. This study reports the results of multivariate analysis on dataset that were obtained from the Bursa Malaysia, DataStream, Bloomberg and annual reports of firms between 2003 and 2012. The empirical results of this study indicate that larger size and independent nonexecutive directors with less frequent directors’ meeting, ethnicity of Malay directors on the board, larger size and more frequent meeting of audit committee have significant effects on reducing the agency problem with internal monitoring function. These lead to a reduction in the cost of raising fund from lenders in capital market. The results also indicate that hiring industry specialist auditors and using non-audit services of external auditors have remarkable influence on reducing the information asymmetry with external monitoring function, which help to lower the cost of debt capital in the capital market. Findings are consistent with the agency theory, signaling theory and cultural theory, whereby internal and external CG mechanisms are associated with effective monitoring, which in turn helps to lower information asymmetry and agency problem in capital markets and consequently increases potential investors and lenders. The findings are of potential interest to policy makers, board members, audit committee members and external auditors.
Impact of Land Use Rights Transfer on Household Labor Productivity: A Study Applying Propensity Score Matching in Chongqing, China

In order to improve the rural labor productivity and farmers’ income, land use transfer was launched and encouraged in recent years, especially the Thirteenth Five-Year Plan (2016–2020). This study aims to shed light on the impact of land use rights transfer on household labor productivity, based on a case study of Chongqing in China. Studies have revealed that land use transfer entails a process of self-selection and does not occur in a random manner. The study, therefore, addressed the issue of sample selection by applying propensity score matching. The study results suggested significant differences in the effects of land use transfer on household labor productivity. Specifically, renting land from other households had a positive effect on total labor productivity (TLP) and agricultural labor productivity (ALP). Moreover, TLP and ALP were found to be higher for households that rented more land or that were located in plain areas. Renting out land had a robust and positive effect on the TLP and non-agricultural labor productivity (NALP). TLP and NALP were also higher for households that rented out more land or that were located in plain areas. These findings suggest that land use transfer should be actively encouraged in plain areas. However, in mountainous areas, there is a need to pay more attention to expanding agriculture to benefit poor and marginalized populations in these areas.
RELIVE: A Markerless Assistant for CPR Training

Cardiopulmonary resuscitation (CPR) is a first-aid key survival technique used to stimulate breathing and keep blood flowing to the heart. Its effective administration can significantly increase the chances of survival in victims of cardiac arrest. In this paper, we propose a markerless system for quality CPR training based on RGB-D (RGB + Depth) sensors, called RELIVE. Then, we report the results of a series of experimental tests conducted to evaluate RELIVE tracking performance. The proposed system is able to accurately track the 3-D position of the hands performing CPR by means of RGB-D sensors to estimate the chest compression rate and depth, providing a real-time visual/audio feedback about the rescuer's performance. Finally, the system usability has been assessed by both healthcare professionals and lay people.
Documents de Travail du Centre d ’ Economie de la Sorbonne Is the Veil of Ignorance Transparent ?

— Theories of justice in the spirit of Rawls and Harsanyi argue that fair-minded people should aspire to make choices for society as if in the original position, that is, behind a veil of ignorance that prevents them from knowing their own social positions. In this paper, we provide a fairly simple framework showing that preferences in front of the veil of ignorance (i.e., in face of everyday risky situations) can be entirely deduced from ethical preferences behind the veil. Moreover, by contrast with Kariv & Zame (2008), in many cases of interest, the converse is not true: Ethical decisions cannot be deduced from economic ones. This not only rehabilitates distributive theories of justice but even proves that standard decision theory in economic environments cannot be exonerated from ethical questioning.
Quality Assurance of Some Heat Treated Meat Products

The aim of this work was to assure the quality of some heat treated meat products, through organoleptic, chemical and microbiological aspects of these products. These products were Luncheon, Frankfurter and Hot dog. A total of 75 samples of final products of Luncheon, Frankfurter and Hot dog (25 / each) were collected randomly from supermarkets in Cairo Province and transferred directly (in a dry icebox) to the laboratory under complete aseptic condition with a minimum of delay. All samples were subjected to organoleptic, chemical and microbiological examination to evaluate their quality status. The results of organoleptic examination revealed that the odour ranged from good to very good, medium to very good and fair to good in Luncheon, Frankfurter and Hot Dog respectively while colour and consistency was good to very good in the three products. The results of chemical analysis revealed that the chemical indicators pH, Total Volatile Nitrogen (T.VN.) and Thiobarbituric Acid (T.B.A.) were within the permissible limits according to EOS (2005). For the chemical examination the mean value of total mesophilic bacterial count was 5.73×102 ± 2.08×102cfu/g, 2.07×106 ± 3.04×105cfu/g, and 1.83×106 ± 2.76×105cfu/g. Also, it was revealed that 100% of the examined samples of total mesophilic count of luncheon were less than the permissible limits according to EOS, (2005) while, 100% of samples of frankfurter and hot dog exceeded the permissible limits when compared with the same standard. The mean value of coliforms count were 2.92 ± 0.31cfu/g, 5.12 ± 0.25 cfu/g, and 6.92 ± 0.27cfu/g for Luncheon, Frankfurter and Hot Dog respectively. The three products were free from Salmonella. Luncheon was free from E.coli and S. aureus while frankfurter and hot dog both of E.coli and S. aureus were isolated in the rate of 80 and 12% respectively. And obtained results indicated that the gram negative coliforms and gram-positive bacteria were present predominantly, Moreover, Moulds and Yeasts counts. Moulds countscfu/g ranged from 0 to 2.1×104 with a mean value of 5.2×102 ± 1.5×102, from 2.2×102 to 3.5×104 with a mean value of 2.9×103 ± 2.1×102 and ranged from 3.1×102 to 4.6×104 with a mean value of 5.3×103 ± 2.2×102 in Luncheon, Frankfurter and Hot Dog respectively. Yeasts counts cfu/g were negative in Luncheon while, ranged from 0to 1.1×104 with a mean value of 3.8×103 ± 2.3×102 and ranged from 0to 1.6×104 with a mean value of 4.5×103 ± 2.1×102 in Frankfurter and Hot Dog respectively. So, it is highly recommended to apply restricted hygiene practices along all steps of processing and storage.