Invasive Bacterial and Malaria Co-Infection and Associated Factors among Pregnant Mothers Attending a Private Tertiary Teaching Hospital in South Western Rural Uganda: Retrospective Review of Records between Feb 2014-Feb 2018

Introduction: Malaria and invasive bacterial infection (IBI) adversely affects the prognosis of pregnant women, globally. However, in sub-Saharan Africa, data on IBI and malaria co-infection among pregnant women is scarce, rather most studies look at Malaria and Invasive bacterial infection dis-jointly. Objectives: We aimed to study the burden of Invasive bacterial and malaria coinfection and associated factors among pregnant mothers attending a private hospital in rural South-Western Uganda. Methods: A cross-sectional study involving retrospective review of records was carried out. The records about pregnant women attending ante-natal clinic at Kampala International University teaching hospital were collected from February 2014 to February 2018.Waiver of consent was thought from relevant Ethical committees. Checklists were used to capture relevant data and data analysis was done using STATA version 14.2. Descriptive statistics, binary crude and adjusted logistic regression were carried out. GJMR-K Classification: NLMC Code: WC 195 InvasiveBacterialandMalariaCo-InfectionandAssociatedFactorsamongPregnantMothersAttendingaPrivateTertiaryTeachingHospitalinSouthWesternRuralUganda RetrospectiveReviewofRecordsbetweenFeb2014-Feb2018 Strictly as per the compliance and regulations of: Invasive Bacterial and Malaria Co-Infection and Associated Factors among Pregnant Mothers Attending a Private Tertiary Teaching Hospital in South Western Rural Uganda: Retrospective Review of Records between Feb 2014-Feb 2018 AbstractIntroduction: Malaria and invasive bacterial infection (IBI) adversely affects the prognosis of pregnant women, globally. However, in sub-Saharan Africa, data on IBI and malaria co-infection among pregnant women is scarce, rather most studies look at Malaria and Invasive bacterial infection dis-jointly. Introduction: Malaria and invasive bacterial infection (IBI) adversely affects the prognosis of pregnant women, globally. However, in sub-Saharan Africa, data on IBI and malaria co-infection among pregnant women is scarce, rather most studies look at Malaria and Invasive bacterial infection dis-jointly. Objectives: We aimed to study the burden of Invasive bacterial and malaria coinfection and associated factors among pregnant mothers attending a private hospital in rural SouthWestern Uganda. Methods: A cross-sectional study involving retrospective review of records was carried out. The records about pregnant women attending ante-natal clinic at Kampala International University teaching hospital were collected from February 2014 to February 2018.Waiver of consent was thought from relevant Ethical committees. Checklists were used to capture relevant Results: Of 367 pregnant women enrolled, the prevalence of Malaria-IBI co-infection was 26% (95%CI 22-31). Being of Muganda tribe was associated with reduced risk of IBI-malaria co-infection as compared to Munyankole; aOR= 0.33, [95% CI 0.11-1.02]. Mothers aged over 28 years were 56% less likely to experience IBI-malaria co-infection as compared to adult mothers below 22 years; aOR=0.44, [95% CI=0.21-0.92]. Those with history of blood transfusion were more likely to have IBI -malaria coinfection compared to those who have never had history of blood transfusion; aOR=1.65, [95%CI=0.96-2.84]. Conclusions & Recommendations: The prevalence of IBImalaria co-infection was high among pregnant women attending Kampala International Teaching hospital of Western Uganda. Factors like age, tribe were significant predictors of the co-infection. There is need for emphasis on education of