Miracle-dz/UniFAR-FTUs huggingface dataset:
DCLK1 phosphorylates the microtubule‐associated protein MAP7D1 to promote axon elongation in cortical neurons

Doublecortin‐like kinase 1 (DCLK1) is a member of the neuronal microtubule‐associated doublecortin (DCX) family and functions in multiple stages of neural development including radial migration and axon growth of cortical neurons. DCLK1 is suggested to play the roles in part through its protein kinase activity, yet the kinase substrates of DCLK1 remain largely unknown. Here we have identified MAP7D1 (microtubule‐associated protein 7 domain containing 1) as a novel substrate of DCLK1 by using proteomic analysis. MAP7D1 is expressed in developing cortical neurons, and knockdown of MAP7D1 in layer 2/3 cortical neurons results in a significant impairment of callosal axon elongation, but not of radial migration, in corticogenesis. We have further defined the serine 315 (Ser 315) of MAP7D1 as a DCLK1‐induced phosphorylation site and shown that overexpression of a phosphomimetic MAP7D1 mutant in which Ser 315 is substituted with glutamic acid (MAP7D1 S315E), but not wild‐type MAP7D1, fully rescues the axon elongation defects in Dclk1 knockdown neurons. These data demonstrate that DCLK1 phosphorylates MAP7D1 on Ser 315 to facilitate axon elongation of cortical neurons. © 2016 Wiley Periodicals, Inc. Develop Neurobiol 77: 419–437, 2017
Low temperature magnetothermoelectric effect and magnetoresistance in Te vapor annealed Bi2Te3

The electrical properties of single crystals of p-type Bi2Te3 are shown to be tuned by annealing as-grown crystals in elemental Te vapor at temperatures in the range of 400–420 °C. While as-grown nominally stoichiometric Bi2Te3 has p-type conductivity below room temperature, Te vapor annealed Bi2Te3 shows a cross over from p- to n-type behavior. The temperature dependent resistivity of the Te annealed crystals shows a characteristic broad peak near 100 K. Applied magnetic fields give rise to a large low temperature magnetothermoelectric effect in the Te annealed samples and enhance the low temperature peak in the resistivity. Further, Te annealed Bi2Te3 shows a large positive magnetoresistance, ∼ 200% at 2 K, and ∼ 15% at room temperature. The annealing procedure described can be employed to optimize the properties of Bi2Te3 for study as a topological insulator.
Managing Word-of-Mouth: A Nonprofit Case Study

Word-of-mouth (WOM) is an important influence on the opinions of donors and their donation behaviors. Against a background of more professional donor relationship management, we investigate about how, if at all, nonprofits (NP) manage WOM. We report an in-depth case study of a single NP. We find that there is widespread appreciation that WOM influences NP performance indirectly through its impact on donor acquisition, donor loyalty, and organizational reputation. Whilst the organization employs networking and WOM practices, it stresses the reduction of negative WOM (NWOM) rather than the promotion of positive WOM (PWOM). Crisis management dominates the NP's WOM-related thinking. We find that PWOM emanates from many organizational influences including donor satisfaction, the welfare service itself, networking practices, external suppliers, alliances, its officers and communication practices including both advertising and public relations. We apply a new model, the eight pillars of WOM, to our analysis of WOM management in the case organization.
The Measurement of the Impacts of the IIC on the End-Users: The Survey

situational factors, also known as facilitating conditions, and feedback. In describing facilitating conditions, Triandis (1979) suggested that the ‘‘geography of the environment may prevent intended behavior. ’’ Because some of IIC technologies were not available to some respondents, accessibility (Culnan, 1984, 1985) was a primary facilitating condition or situation constraining utilization [see Fig. 1 in the preceding article by Goodhue (1997)] . For this reason, accessibility was added as a control variable in the analyses. In addition, one of the managerial problems which the IIC faced was how to allocate its scarce resources. Thus, it seemed quite appropriate to measure the feedback construct via ‘‘allocation of resources,’’ i.e., would users allocate more, less, or the same resources to this technology in the future? Decisions about future resource allocation is one form of feedback from an individual’s experience with the technologies. Presumably respondents would like to see more resources allocated to technologies which have had a high impact on their tasks and to those which are a good fit to their tasks. Our goal in this effort is twofold: First, to check the validity of the Task–Technology Fit (TTF) model, and second, using the TTF model as a base, to determining the impact of the IIC on its target population. The TTF model can be considered to be supported if the primary hypothesized linkages in the research model are found to be significant. These linkages include: (1) Task–technology fit (controlling for IT accessibility) leads to utilization; (2) both fit and utilization lead to performance impacts; and (3) both performance impacts and fit lead to The Measurement of the Impacts of the IIC on the End-Users: The Survey
Woody species diversity and important value indices in dense dry forests in Abdoulaye Wildlife Reserve (Togo,West Africa)

Dry forests are seriously under threats, mostly linked to human disturbance. In Togo where continuous deforestation is ongoing, it important to assess woody species diversity that maintain forest structure and functions. In that concern, this study was carried out in Abdoulaye Wildlife Reserve (AWR) with a specific objective to assess woody species diversity. A total of 258 plant species belonging to 119 genera and 63 families were found in AWR dry forests. Of this total, 67 woody species with 903 individuals and 52 genera were recorded. The highest relative frequencies were recorded byAnogeissus leiocarpa (83.37%), Pouteria alnifolia var. alnifolia (73.37%), Cola gigantea (50%),Diospyros mespiliformis (50%) and Dialium guineense (40%). The lianas species are dominated byRourea coccinea, Dioscorea dumetorum, Cissus populnea, Dioscorea burkilliana whereas the dominated herbaceous of the undergrowth layer were Anchomanes difformis, Chromolaena odorata,Olyra latifolia and Oplismenus hirtellus. Three stand groups were revealed and the study highlighted trees bushfire and breakage as main threats on species diversity. These human pressures were highest in GIII. Globally, Pielou’s index varied from 0.78 to 0.85. All these groups were dominated by A.leiocarpa. The study suggests conservation strategies to protect woody species against anthropogenic pressures (for example, protection from or reducing the frequency and/or intensity of disturbance, especially wood-cutting and bushfires). Key words: Togo, biodiversity, woody species, sustainable management, dense dry forests.
Gamma-ray burst progenitors and the population of rotating

In our quest for gamma-ray burst (GRB) progenitors, it is relevant to consider the progenitor evolution of normal supernovae (SNe). This is largely dominated by mass loss. We discuss the mass-loss rate Ṁ for very massive stars up to 300M . These objects are in close proximity to the Eddington Γ limit. We describe the new concept of the transitional mass-loss rate, enabling us to calibrate wind mass loss. This allows us to consider the occurrence of pair-instability SNe in the local Universe. We also discuss luminous blue variables and their link to luminous SNe. Finally, we address the polarization properties of Wolf– Rayet (WR) stars, measuring their wind asphericities. We argue to have found a group of rotating WR stars that fulfil the required criteria to make longduration GRBs.
Myopia, customer returns and the theory of planned behaviour

As a prevalent and growing form of customer behaviour, deshopping is on the rise. Retailers' focus on good customer service and the offering of lenient returns polices has led to the growth in this fraudulent behaviour of customers in returning goods. This paper considers retailer myopia in the context of dishonest customer returns, applying the Theory of Planned Behaviour (TPB) using a quantitative questionnaire with 535 female consumers. The findings highlight the extent of the behaviour with 50% admitting to partaking in deshopping. The TPB variables can be utilised to manage and prevent deshopping. The results indicate that currently these customers perceive it to be easy to deshop as there are no consequences with the result that such behaviour continues to grow. If retailers were less myopic they would monitor returns more thoroughly and make it less easy for such customers to get away with undesirable deshopping behaviour. The paper makes recommendations for retailers to manage or alter perceived behavioural characteristics for customers, which in turn, would reduce tendencies for dishonesty in customers returning goods for refunds. Retail myopia is evident with deshopping behaviour with consequences for retailers in time, effort and costs.
Determinants and Value of Enterprise Risk Management: Empirical Evidence from the Literature

The development of an enterprise risk management (ERM) program enables companies to manage corporate risks in a holistic manner as opposed to the silo‐based perspective in traditional risk management frameworks. One main question in this regard is what factors drive the implementation of an ERM system in companies and whether ERM programs can actually create value once implemented. This article addresses these questions by conducting a comparative assessment of empirical evidence from the literature regarding the determinants of ERM and its value once implemented. In doing so we are able to illustrate differences in model specifications and the underlying data. Our literature study shows that particularly the company size and the level of institutional ownership are significantly positively related to the implementation of ERM in most empirical studies and, furthermore, that ERM generally has a (significant) positive impact on corporate value and performance (to a different extent and depending on the focus of the studies). However, geographic and/or industrial restrictions regarding the underlying data sets partly limit the generalization of the empirical results.
The effects of sale signs on consumer intentions to visit a store

This study examines consumer attention to and the perceived aesthetics of sale signs, such as the designs (size and color) of the Point of Purchase (POP) sale signs outside shops, and how these factors affect consumer intention to visit a shop based on expectation regarding the stores. External store stimuli were created using the Sketchup 8 software package. Research found that influences on intention to visit a store can differ depending on how the sale signs are perceived. Consumer expectations of the store can differ depending on the size of sale signs and the colors employed. We expect that the outcomes of this study will aid fashion brands in designing sale signs that reflect their brand value and image. Sale sign planning and utilization as a part of the strategy will be the key factor that can affect consumer behavior.
Political Connections and Dividends Payout in Malaysia: The Influence of Institutional Investors

This study examines the agency problem of expropriation using dividends in politically connected firms and the relevance of institutional investors in limiting this problem. Our results suggest that politically connected firms (PCON) have a preference to pay lower dividends whereas institutional investors are more likely to demonstrate a higher preference for higher dividends. The interaction effects between political connection and institutional investors indicate a positive relationship with dividends which suggest that, in the presence of institutional investors, politically connected firms are more likely to be associated with higher dividends payout. This further emphasizes on the role of institutional investors in limiting expropriation concerns within PCON firms. Our further analysis also suggests that institutional investors are more concerned with higher capital investment which in turn creates the potential to enhance firm valuation (contrary to PCON firms). Our findings are important especially to regulators, in order for them to promote and facilitate the participations of institutional investors with a view to constrain the behavior of PCON firms, enhance firm value and protect shareholders’ interest.
Agency costs and corporate performance: Analysis of public listed companies in Bursa Malaysia

The agency theory is one of the company’s theories in a way that company is explained as a set of contractual explicit of implicit relationships between principal (shareholders) and agent (management). The role of second party is to perform certain tasks and authorized to make decisions on behalf of the first party. Meanwhile corporate performance is very crucial for market efficiency since it will influenced the decision made by the market players and internal investors of the Companies. This study examines the relationship of agency costs with corporate performance. Five variables of agency costs proxies are analysed: Debt Ratio, Firm’s size, Growth, Expense and Efficiency. While the corporate performance is measured by Return on Assets (ROA) and Return on Equity (ROE) . ROA gives an idea as to how efficient management is at using its assets to generate earnings while ROE measures a corporation’s profitability by revealing how much profit a company generates with the money shareholders have invested. Besides, this study examined whether there are any correlation between agency costs which is proxied by Debt Ratio, Firm’s size, Growth, Expense and Efficiency Ratio; against Corporate Performance for the Top 50 and Bottom 50 Public Listed Companies in Bursa Malaysia. This study used secondary data which is the data from Public Listed Companies in Bursa Malaysia. From the total 814 population, the 100 sample was taken from different categories which is the Top 50 and the Bottom 50 companies covering over period of 5 years from 2008 to 2012. It is found that for a certain extent, the Agency costs play an important roles in relation to the Corporate Performance.The result gathered after analyzing the data acquired from Bursa Malaysia explained that only Firm’s size, Expense and Efficiency Ratio has the relationship with the significant value of 0.000. Debt ratio and growth variables was not significant with Corporate Performance
Investigating work engagement in the service environment

Purpose – Frontline employees (FLEs) represent a major source of value creation for the modern firm. As such, firms are constantly evaluating different attributes of potential and current employees in the hopes of attracting, retaining, and rewarding key employees. Recently, the construct of work engagement has garnered interest as an important indicator of employee performance. However, much is unknown about this construct with regards to antecedents, outcomes and measurement. Thus, the purpose of the current research is to contribute to the developing literature on work engagement. Design/methodology/approach – Data were collected from FLEs across high and low customer contact service contexts. The hypothesized relationships in the model were tested using structural equation modeling (SEM). Findings – This research provides empirical evidence that service climate, job satisfaction and affective commitment influence work engagement. Employee's work engagement subsequently impacts constructs such as caree.
Nurses' views on dignity in care.

AIM The aim of the RCN dignity survey was to gain the perspectives of nurses, healthcare assistants and nursing students regarding the maintenance and promotion of dignity in everyday practice. This article presents survey respondents' experiences of providing dignified care for older people. METHOD A survey questionnaire was developed including fixed response and free text questions. A survey link was emailed to RCN members. Of the 2,048 respondents, 1,110 (54 per cent) worked with older people. These responses were analysed using an Excel spreadsheet for the quantitative data and the free text data were analysed thematically. RESULTS The respondents perceived that the physical environment and organisation influenced the provision of dignified care. Respondents described how they endeavoured to promote dignity during care activities which might threaten dignity through thoughtful planning, sensitive communication, preserving privacy and promoting choice. CONCLUSION A conducive physical care environment, a supportive organisation and individual nurses' actions can do much to promote the dignity of older people while they are undergoing health care.
Dark-light Change of Iris Parameters and Related Factors Among American Caucasians, American Chinese, and Mainland Chinese

Purpose: To assess the distribution of dark-light changes in iris features and associated factors amongst American Caucasians, American Chinese and mainland Chinese aged 40 years and over. Methods: Four gender- and age-matched cohorts: Caucasians, American Chinese, Southern Chinese and Northern Chinese comprised the study population. Anterior segment optical coherence tomography (ASOCT) images were acquired under dark and light conditions. Customized software was used to calculate iris thickness at 750 μm from the scleral spur (IT750), iris curvature (ICurv), iris area (IArea), and pupil diameter (PD) from ASOCT images. Results: Data from 121, 124, 121 and 120 subjects were available for American Caucasian, American Chinese, Southern and Northern Chinese subjects respectively. Caucasians had significantly less dark-light change (Δ) of IT750 and greater ΔPD than Chinese. When using multiple linear regression analyses, the inter-ethnic difference for ΔIT750 was independent of age, gender, refractive error, anterior chamber width and axial length. After controlling for ΔPD, ΔICurv was found to be inversely associated with age (β = −0.001, P = 0.001). Independent predictors of greater ΔPD included younger age (β = −0.02, P = 0.001), Caucasian ethnicity (β = −0.022, P = 0.009) and wider anterior chamber (β = 0.18, P = 0.03). Conclusions: Compared with Caucasians, Chinese irides show greater thickening with light to dark adaptation despite the lesser change of PD in Chinese. The change of iris area per unit change of pupil diameter from dark to light did not differ between ethnicities. These dynamic characteristics intrinsic to Chinese irides may partially account for the substantially increased risk for angle closure among this ethnic group.
In vivo EIS characterization of tumour tissue properties is dominated by excess extracellular fluid

Electrical impedance spectroscopy (EIS) is a non-ionizing, non-invasive technique which can be used to detect the presence of malignant tumours based on their electrical properties. Although it has been suggested that the edema which accompanies tumours strongly influences EIS tumour characterization, such information has not, until now, been documented in the literature. Growing intramuscular rodent tumours were imaged using magnetic resonance imaging (MRI) and EIS at several time points post-tumour implantation. The amount of edema associated with the tumours was calculated from the MRI images. Electrical parameters (resistivity, permittivity, fluid index ratio and peak frequency) were extracted from the EIS spectra. Taken together, the resulting electrical parameters strongly indicate that edema is the dominating pathological feature in EIS characterization and can at times conceal the presence of the tumour. Receiver operating characteristic analysis supports these findings.
A Survey on the Perceptions of Consumer Organizations to Promote Risk Communication for Food Additives

Abstract Consumer organizations usually lead the opinions of the consumers. This study was performed to investigate the perceptions and information needs of consumer organizations on food additives for the promotion of risk communication. A survey was conducted for 4 weeks in March 2012 by using a self-administered questionnaire consisting of 32 questions. Total 111 responses were collected for analysis. ‘Safety (91.0%)’ was the most important factor influencing the purchase of processed food, and both ‘food additives (24.3%)’ and ‘environmental pollution (23.4%)’ were considered as main risk factors. The longer the career of the members had, the higher negative perceptions on food additives (p<0.01). About 70% of the respondents who had known KFDA’s researches on evaluating safety of food additives answered that researches were not enough to make sure the safety. Although lectures and other domestic organization were the main channels for getting information, ‘TV’ was considered as the most suitable way for it. ‘Poor risk communication (32.4%)’ was pointed out as the serious problem of government’s food safety policy. Based on these results, consumer organizations’ low level of trust on government should be overcome by continuous supply of information what they need to facilitate risk communication on food additives. Key words: food additives, consumer organization, perception, risk communication
The Impact of the Precision and Scale of News on Trading Volume: Evidence from Volume Following Profit Warnings

We contribute new empirical evidence on the determinants of trading volume for stocks. First, we investigate whether the precision of the information in a public announcement affects volume. We compare volume following profit warnings that offer a new quantitative earnings forecast with volume following those that simply announce that earnings will fall short of expectations. Second, for the sample of warnings that include a quantitative forecast, we examine the impact on volume of the size of the earnings surprise. We find that volume is higher following warnings that include a new earnings forecast, and higher the larger is the surprise. January 2006 George Bulkley Ioannis Krassas Xfi Centre for Finance University of Exeter Exeter Devon EX4 4RJ UK Contact Author: I.G. Bulkley@exeter.ac. uk Xfi, Streatham Court, University of Exeter, Exeter, EX4 4ST, UK Tel: 44-1392-263214 Fax: 44-1392-262525
Service‐dominant logic: a necessary step

Purpose – The purpose of this paper is to respond to the criticism O'Shaughnessy and O'Shaughnessy made of service‐dominant logic in EJM, on behalf of both the paper and the worldwide community of scholars that have embraced S‐D logic as historically informed, integrative, transcending and rich in its potential to generate theoretical and practical contributions.Design/methodology/approach – The paper is a critical, conceptual analysis of the fallacious arguments that O'Shaughnessy and O'Shaughnessy developed to argue against the emerging and rapidly developing service‐dominant logic.Findings – The paper shows that, contrary to the claims of O'Shaughnessy and O'Shaughnessy, S‐D logic: is neither regressive nor intended to displace all other marketing perspectives; is not advocating technology at the expense of explanatory theory; and is pre‐theoretic and intended to be soundly grounded in a manner to assist theory construction.Research limitations/implications – Theory advancement is critical to marketing.
The multiple banking behaviour of Singaporeans

This study, using a sample of adult Singaporeans, established that 76.8 per cent of its respondents engaged in multiple banking. The Post Office Savings Bank was main bank to 61.3 per cent of the respondents, while the local full licence banks were main bank to 35.1 per cent of the respondents. These same banks held 27.6 per cent and 66.1 per cent respectively of subsidiary bank relationships. Multiple bank customers were typified as being people who were tertiary educated, were Chinese and were paid an income of $2,000 p.m. and above. No significant differences were found upon comparing single and multiple banking customers based on five psychographic characteristics.