Miracle-dz/UniFAR-FTUs huggingface dataset:
The survival of lambs in shelter declines at high stocking intensities

This experiment evaluated the effect of stocking intensity at lambing on lamb survival. A randomised block design with three replicates compared stocking rates of 16 and 30 ewes/ha. Twin-bearing Merino ewes (n = 69) that had been mated with Poll Dorset × White Suffolk rams were placed in paddocks sheltered with rows of hessian, with 8 or 15 ewes per 0.5-ha plot for the low and high stocking rates, respectively. The survival of lambs born alive at the high stocking rate (63%) was 24% less (P = 0.002) than for those at the low stocking rate (83%), and was associated with a higher (P 0.05) in lamb birthweight, marking weight, ewe liveweight or condition, suggesting nutritional conditions between the stocking rates were similar. The results suggest caution in using lambing strategies which require high stocking rates.
INFERENCE FOR THE JUMP PART OF QUADRATIC VARIATION OF ITÔ SEMIMARTINGALES

Recent research has focused on modeling asset prices by Itô semimartingales. In such a modeling framework, the quadratic variation consists of a continuous and a jump component. This paper is about inference on the jump part of the quadratic variation, which can be estimated by the difference of realized variance and realized multipower variation. The main contribution of this paper is twofold. First, it provides a bivariate asymptotic limit theory for realized variance and realized multipower variation in the presence of jumps. Second, this paper presents new, consistent estimators for the jump part of the asymptotic variance of the estimation bias. Eventually, this leads to a feasible asymptotic theory that is applicable in practice. Finally, Monte Carlo studies reveal a good finite sample performance of the proposed feasible limit theory.
Mothering Work and Perinatal Transfer: An Institutional Ethnographic Investigation

Background While maternal or infant transfer is generally the safest course of action when health complications arise, the process of shifting from one hospital to another is stressful for mothers and their infants. There is limited understanding of how institutional processes coordinate patient transfer in ways that increase tensions for women and their families who are trying to navigate the institutional systems during health crises. Methods This institutional ethnographic study explored womens’ experience of transfer. Interviews were conducted with a purposive sample of six childbearing women. The analysis highlights tensions and contradictions between patient care and institutional demands and shows how ordinary institutional decision-making practices impacted participants in unexpected ways. Results Women experienced uncertainty and stress when trying to convince health-care providers they needed care. Before, during, and after transfer, participants navigated home responsibilities, childcare, and getting care closer to home in difficult circumstances. Conclusion The effort and skill women need to care for their infants and families as they are transferred is extraordinary. This study offers insight into the resources and support childbearing women need to accomplish the work of caring for their families in the face of perinatal crisis and multiple transfers.
Hand Motor Actions of Children With Cerebral Palsy Are Associated With Abnormal Sensorimotor Cortical Oscillations

Background. The neuroimaging literature on cerebral palsy (CP) has predominantly focused on identifying the structural aberrations (eg, fiber track integrity), with very few studies examining neural activity within the key networks that serve the production of hand movements. Objective. We aimed to start to fill this knowledge gap by using magnetoencephalographic brain imaging to quantify the temporal dynamics of the sensorimotor oscillations during a hand motor action. Methods: Children with CP (n = 12; MACS [Manual Abilities Classification System] levels I-III) and typically developing (TD) children (n = 26) performed an arrow-based version of the Eriksen flanker task where a button press was performed with either the second or third digit of the right hand depending on the arrow’s direction. Results: Overall, the children with CP were less accurate and had slower reaction times compared with the TD children. These behavioral differences were closely linked with aberrant sensorimotor cortical oscillations seen in the children with CP. Compared with the TD children, the children with CP had a weaker gamma (68-82 Hz) response during motor execution and a weaker post-movement beta rebound (PMBR; 14-26 Hz) response on movement termination. Moreover, we observed a significant correlation between the amplitude of the gamma and PMBR with reaction time, with weaker gamma and PMBR responses being linked with slower reaction times. Conclusions: Overall, these results suggest that aberrations in motor-related gamma and beta cortical oscillations are associated with the impaired hand motor actions seen in children with CP.
Breast cancer prognostic staging and internal mammary lymph node metastases: a brief overview.

The incidence of cancer worldwide continues to increase, and it remains the second leading cause of death (1). Of the 17.5 million cancer cases worldwide in 2015, breast cancer was the most common in women (2.4 million cases) and was the leading cause of cancer deaths (523,000) in women (1). As such, the importance of effectively and efficiently communicating disease characteristics and prognosis remains essential to patients, clinicians, and researchers.
Change in Physical Activity after Diagnosis of Diabetes or Hypertension: Results from an Observational Population-Based Cohort Study

Background: Chronic diseases like diabetes mellitus or hypertension are a major public health challenge. Irregular physical activity (PA) is one of the most important modifiable risk factors for chronic conditions and their complications. However, engaging in regular PA is a challenge for many individuals. The literature suggests that a diagnosis of a disease might serve as a promising point in time to change health behavior. This study investigates whether a diagnosis of diabetes or hypertension is associated with changes in PA. Methods: Analyses are based on 4261 participants of the population-based KORA S4 study (1999–2001) and its subsequent 7-and 14-year follow-ups. Information on PA and incident diagnoses of diabetes or hypertension was assessed via standardized interviews. Change in PA was regressed upon diagnosis with diabetes or hypertension, using logistic regression models. Models were stratified into active and inactive individuals at baseline to avoid ceiling and floor effects or regression to the mean. Results: Active participants at baseline showed higher odds (OR = 2.16 [1.20;3.89]) for becoming inactive after a diabetes diagnosis than those without a diabetes diagnosis. No other significant association was observed. Discussion: As PA is important for the management of diabetes or hypertension, ways to increase or maintain PA levels in newly-diagnosed patients are important. Communication strategies might be crucial, and practitioners and health insurance companies could play a key role in raising awareness.
Cortical correlates of creative thinking assessed by the figural Torrance Test of Creative Thinking

Torrance Test of Creative Thinking is the most widely used form of creativity test. Although creativity assessed using the figural form of Torrance Test of Creative Thinking has been considered non-unidimensional, the structural correlates for each separable dimension have yet to be explored. The present study investigated the underlying cortical structure of separable dimensions for creativity using the figural Torrance Test of Creative Thinking. To this end, we recruited healthy young adults and conducted a regression analysis of the figural Torrance Test of Creative Thinking scores of gray matter volume after factorizing the five subscales using exploratory factor analysis. As a result, two factors of the figural Torrance Test of Creative Thinking were identified: (1) ‘FO’ factor consisting of fluency and originality and (2) ‘RAS’ factor consisting resistance to premature closure, abstractness of titles, and sophistication/elaboration. Subsequently, the FO factor showed a positive association with cerebral volumes in the parieto-temporal regions of the left angular gyrus and the right inferior parietal lobule, inferior and middle temporal, and parahippocampal gyri, which overlapped the default network. The RAS factor showed a positive correlation with the fronto-temporal regions including the bilateral temporal area, the left inferior parietal, and the right dorsolateral prefrontal regions representing the semantic control network. Our findings revealed the morphological substrates for the figural Torrance Test of Creative Thinking depending on two creative dimensions. The implications of the results are discussed.
Morphological, Structural and Chemical Properties of p- type Porous Silicon Produced by Electrochemical Etching

In this paper, the nanocrystalline porous silicon (PS) films are prepared by electrochemical etching of p-type silicon wafer with current density (7 mA/cm 2 ) and etching times on the formation nano-sized pore array with a dimension of around different etching time. The films were characterized by the measurement of XRD, FTIR spectroscopy and atomic force microscopy properties (AFM). We have estimated crystallites size from X-Ray diffraction about nanoscale for porous silicon and Atomic Force microscopy confirms the nanometric size Chemical fictionalization during the electrochemical etching show on the surface chemical composition of PS. The etching possesses inhomogeneous microstructures that contain a-Si clusters (Si3-Si-H) dispersed in amorphous silica matrix . From the FTIR analyses showed that the Si dangling bonds of the as-prepared PS layer have large amount of Hydrogen to form weak Si -H bonds. The atomic force microscopy investigation shows the rough silicon surface, with increasing etching process (current density and etching time) porous structure nucleates which leads to an increase in the depth and width (diameter) of surface pits. Consequently, the surface roughness also increase.
Whole Language Reading Education for Middle School Students with Learning Disabilities.

Whole language reading education is a constructivist view of learning with particular emphasis on the development of literacy. Constructivism asserts that human beings develop concepts through their own intellectual interactions and actions with the world. In whole language reading classrooms acceptance of learners means that the whole language reading teachers develop the classroom environment and the curriculum for and with the students, to meet their needs and excite them in learning about what interests them, as well as covering curriculum guidelines. The instruction received by students with learning disabilities (LD) often takes place in the resource room. Little attention is paid to the individual needs of the students with learning disabilities despite the legal requirement to do so. This paper, a literature review, addresses two areas pertaining to the development of reading ability. First, the paper investigates the development of reading ability in whole language classrooms. Then, it explores the development of reading ability in students with learning disabilities, including motivating an LD middle school student to read. It also discusses middle school student needs and preferences in reading. Contains 48 references. (NKA) ENTIRE DOCUMENT: POOR PRINT QUALITY Reproductions supplied by EDRS are the best that can be made . from the on final document PERMISSION TO REPRODUCE AND DISSEMINATE THIS MATERIAL HAS BEEN GRANTED BY TO THE EDUCATIONAL RESOURCES INFORMATION CENTER (ERIC) 1 Whole Language Reading Education for Middle School Students with Learning Disabilities John A. Sargent Donnie Bickham Middle School Louisiana Tech University A Paper Presented at the Mid South Education Research Association Conference Chattanooga, Tennessee U.S. DEPARTMENT OF EDUCATION November 6th 2002 Office of Educational Research and Improvement EDUCATIONAL RESOURCES INFORMATION CENTER (ERIC) This document has been reproduced as received from the person or organization originating it. Minor changes have been made to improve reproduction quality. Points of view or opinions stated in this document do not necessarily represent official OERI position or policy.
Association between work environment and implicit rationing of nursing care: An integrative literature review.

AIM To systematically evaluate the effect of working environment on implicit rationing of nursing care. BACKGROUND Research has established direct and indirect associations between work environment and adverse patient outcomes.However, the causal nature of this relationship is uncertain, and implicit rationing has been proposed as a mediating factor between the work environment and patient outcomes. EVALUATION Eight databases were searched for articles published between May 2000 and May 2019. KEY ISSUES The reviewed articles provided evidence for the negative correlation between working environment and implicit rationing in 15 studies,and one of the studies showed that the correlation was not strong.There were differences in the levels of implicit rationing in different hospitals, units and shifts. CONCLUSION The degree of influence of various factors in the working environment on implicit rationing is different.In addition.The working environment is only one of the factors that affects implicit rationing. IMPLICATION FOR NURSING MANAGEMENT Nursing managers initiatives to improve nurses' work environments should include improve nurses' perception of the adequacy of staffing and resources and improving teamwork to decrease nursing care left undone,so as to improve nurse outcomes and quality of care.
The Clinical Characteristics of Pediatric Non-Infectious Uveitis in Two Tertiary Referral Centers in Turkey

ABSTRACT Purpose: To report the manifestations, patterns of disease, treatment strategies and outcomes in pediatric patients with noninfectious uveitis. Methods: Demographic information of 76 cases was recorded. Symptoms, anatomic location, laterality, visual acuity (VA), intraocular pressure, associated systemic diseases, therapeutic strategies, side effects, complications were reviewed. Results: Thirty-one patients were diagnosed as uveitis on routine surveillance because of underlying systemic disease. The most common anatomic location was intermediate uveitis (34.2%). Juvenile idiopathic arthritis (JIA) was the most common underlying systemic disease (25%). Glaucoma was the most common complication (7.7%). The patients with refractory uveitis received adalimumab (26.5%), infliximab (4.6%) and tocilizumab (3.1%). The mean first-year VA was between 20/32 and 20/20 in 116/140 eyes. Conclusion: Most pediatric noninfectious uveitis cases have bilateral intermediate uveitis. JIA was the most common systemic association. The first-year VA was good in most eyes which may be due to early use of corticosteroid-sparing agents.
Simultaneous Immunization with Multivalent Norovirus VLPs Induces Better Protective Immune Responses to Norovirus than Sequential Immunization

Human noroviruses (NoVs) are a genetically diverse, constantly evolving group of viruses. Here, we studied the effect of NoV pre-existing immunity on the success of NoV vaccinations with genetically close and distant genotypes. A sequential immunization as an alternative approach to multivalent NoV virus-like particles (VLPs) vaccine was investigated. Mice were immunized with NoV GI.3, GII.4-1999, GII.17, and GII.4 Sydney as monovalent VLPs or as a single tetravalent mixture combined with rotavirus VP6-protein. Sequentially immunized mice were primed with a trivalent vaccine candidate (GI.3 + GII.4-1999 + VP6) and boosted, first with GII.17 and then with GII.4 Sydney VLPs. NoV serum antibodies were analyzed. Similar NoV genotype-specific immune responses were induced with the monovalent and multivalent mixture immunizations, and no immunological interference was observed. Multivalent immunization with simultaneous mix was found to be superior to sequential immunization, as sequential boost induced strong blocking antibody response against the distant genotype (GII.17), but not against GII.4 Sydney, closely related to GII.4-1999, contained in the priming vaccine. Genetically close antigens may interfere with the immune response generation and thereby immune responses may be differently formed depending on the degree of NoV VLP genotype identity.
Next-Generation Multimodality of Nanomedicine Therapy: Size and Structure Dependence of Folic Acid Conjugated Copolymers Actively Target Cancer Cells in Disabling Cell Division and Inducing Apoptosis

Nanomedicine as a multimodality treatment of cancer utilizes the advantages of nanodelivery systems of drugs. They are superior to the clinical administration of different therapeutic agents in several aspects, including simultaneous delivery of drugs to the active site, precise ratio control of the loading drugs and overcoming multidrug resistance. The role of nanopolymer size and structural shape on the internalization process and subsequent intracellular toxicity is limited. Here, the size and shape dependent mechanism of a functionalized copolymer was investigated using folic acid (FA) covalently bonded to the copolymer poly (styrene-alt-maleic anhydride) (SMA) on its hydrophilic exterior via a biological linker 2,4-diaminobutyric acid (DABA) to target folic acid receptors (FR) overly expressed on cancer cells actively. We recently reported that unloaded FA-DABA-SMA copolymers significantly reduced cancer cell viability, suggesting a secondary therapeutic mechanism of action of the copolymer carrier post-internalization. Here, we investigated the size and shape dependent secondary mechanism of unloaded 350 kDa and 20 kDa FA-DABA-SMA. The 350 kDa and 20 kDa copolymers actively target folic acid receptors (FR) to initialize internationalization, but only the large size and sheet shaped copolymer disables cell division by intracellular disruptions of essential oncogenic proteins including p53, STAT-3 and c-Myc. Furthermore, the 350 kDa FA-DABA-SMA activates early and late apoptotic events in both PANC-1 and MDA-MB-231 cancer cells. These findings indicate that the large size and structural sheet shape of the 350 kDa FA-DABA-SMA copolymer facilitate multimodal tumor targeting mechanisms together with the ability to internalize hydrophobic chemotherapeutics to disable critical oncogenic proteins controlling cell division and to induce apoptosis. The significance of these novel findings reveals copolymer secondary cellular targets and therapeutic actions that extend beyond the direct delivery of chemotherapeutics. This report offers novel therapeutic insight into the intracellular activity of copolymers critically dependent on the size and structural shape of the nanopolymers.
Analysis of Factors Effective on Loyalty of Customers of Websites

Today, the issue of keeping and strengthening customer loyalty is considered as a strategic challenge for the companies which are concerned how to retain and develop their competitive position in the market. They bear high costs to understand this concept and to achieve the practical approaches to strengthen it; because as the competition is intensified and the quantitative and qualitative level of the services in the selection area of the customers, it is considered as a vital task to provide the services which would be able to attract their attention and change them into the permanent customers of the services provided by the organization. The present investigation examines the quality system, information quality, interface design quality and their effects on the satisfaction and trust of the customers of websites as well as the effects of such trust and satisfaction on loyalty of customers of websites. Statistical population of this research includes the customers of Center Market website among which a sample of 320 people was selected. The data were analyzed using SPSS and AMOS statistical software and the Structural Equation Modeling (SEM) was used as the statistical method. The results so achieved show that system quality and interface design quality affect significantly on the satisfaction and trust of the customers. Furthermore, the trust and satisfaction are considerably effective on the customer loyalty.
The impact of threat of shock-induced anxiety on the neural substrates of memory encoding and retrieval

Abstract Dysfunctional memory processes are widely reported in anxiety disorders, but the underlying neurocognitive mechanisms are unclear. Recent work shows that the impact of anxiety on memory depends on the context and memory modality. For instance, threat of shock, a translational within-subject anxiety induction, has been shown to impair the encoding of facial stimuli, while improving spatial working memory (WM) accuracy. The present study aimed to delineate the neural circuitry regulating these opposing behavioural effects. Thirty-three healthy volunteers performed the previously assessed facial recognition and a spatial WM tasks inside an fMRI scanner, under alternating within-subject conditions of threat or safe from shock across encoding and retrieval. Facial recognition impairments were replicated when threat was selectively induced at encoding. Neuroimaging results suggest that this effect was driven by increased competition for attentional resources within the anterior cingulate cortex, in which activation correlated positively with stress levels. The impact of threat on spatial WM performance did not, however, replicate in the fMRI environment. Nevertheless, state-dependent hippocampal activation was observed in both tasks. These findings suggest a neurocognitive mechanism by which anxiety impairs facial recognition as well as a state-dependent hippocampal activation pattern, which may putatively underline retrieval of negative experiences in anxiety.
Human-felid conflict: a review of patterns and priorities worldwide

Abstract Conflict between people and felids is one of the most urgent wild cat conservation issues worldwide, yet efforts to synthesize knowledge about these conflicts have been few. For management strategies to be effective a thorough understanding of the dynamics of human-felid conflicts is necessary. Here we present the results of a cross-species, systematic review of human-felid conflicts worldwide. Using a combination of literature review and geographical information system analyses, we provide a quantitative as well as qualitative assessment of patterns and determinants that are known to influence the severity of human-felid conflicts, and a geographical overview of the occurrence of conflict worldwide. We found evidence of conflict affecting over 75% of the world's felid species. The severity of conflict increases with felid body mass and is of greatest conservation significance to nine species: caracal, cheetah, Eurasian lynx, jaguar, leopard, lion, puma, snow leopard and tiger. We also reveal specific gaps in knowledge about human-felid conflicts, and required actions within this aspect of felid conservation. With only 31% of implemented management strategies having been evaluated scientifically, there is a need for greater and more rigorous evaluation and a wider dissemination of results. Also urgently required are standardized reporting techniques to reduce the current disparity in conflict reporting methods and facilitate resolution of patterns and trends in the scale of human-felid conflict worldwide. This review provides a basis both for further synthesis and for the coordination of human-felid conflict management among researchers, practitioners and organizations.