Miracle-dz/UniFAR-FTUs huggingface dataset:
Primary Repair of Knee Dislocations: Results in 25 Patients (28 Knees) at a Mean Follow-up of Four Years

Objective: To investigate the outcomes of knee dislocations treated with primary repair and an early rehabilitation protocol. Design: Retrospective. Settings: Level 1 Trauma Center. Patients: Consecutive patients with knee dislocation referred to a single surgeon for care between 1994 and 2002 were included, for a total of 27 patients with 30 knee dislocations. Twenty-five patients (28 knees) were evaluated by an independent observer at a mean of 48 months (13-82 months). Intervention: All patients underwent primary repair of all injured ligaments using a consistent technique and early rehabilitation protocol. Main Outcome Measurements: In addition to range of motion and stability assessment, Lysholm and Tegner scores were used to evaluate outcome. Results: The mean post-operative Lysholm score was 89.0. Range of motion analysis for the 22 unilateral dislocations available for examination showed a mean extension loss of 1.9° and mean flexion loss of 10.2°, with a mean arc of motion of 119.3°. Overall, the knees were found to be clinically stable. Conclusions: Primary repair of ligaments coupled with an early rehabilitation program provides comparable outcomes to published results of ligament reconstruction. Primary repair of ligaments in the dislocated knee should be considered as an effective option in the trauma population.
Low-frequency noise of advanced memory devices

This paper reviews the application of low-frequency noise and Random Telegraph Signal (RTS) studies on advanced memory devices, namely, Metal-Insulator-Metal capacitors with SrTiOx as insulator, peripheral transistors for Dynamic Random Access Memories and Resistive Random Access Memory structures. In the first two cases, flicker noise is used to analyze the quality or defectiveness of the gate stack, while in the third case, both flicker and RTS noise provide information on the carrier trapping and transport.
Comparison of similarity measures for clustering Turkish documents

Text clustering has become an important part of the web data organization with the rapid growth of the World Wide Web (www). Clustering simplifies web search engine work by grouping large amount of documents, retrieved according to a given query. Similarity measures used in clustering affect the output of the grouping directly. Most of the document clustering techniques rely on single term analysis of text, such as vector space model. In order to improve grouping of Turkish documents, we investigate several similarity measures based on the semantic similarity of terms. Moreover, some techniques for calculating documents similarity are studied. The aim of this paper is to study the effects of semantic and single term similarity measures to the clustering results of Turkish documents. All experiments are carried out on Turkish web sites, taking into account the relationships of terms based on the ontology for the Turkish language.
Ion channel blockers and spinal cord injury

The activation of a delayed secondary cascade of unsatisfactory cellular and molecular responses after a primary mechanical insult to the spinal cord causes the progressive degeneration of this structure. Disturbance of ionic homeostasis is part of the secondary injury process and plays an integral role in the early stage of spinal cord injury (SCI). The secondary pathology of SCI is complex and involves disturbance of the homeostasis of K+, Na+, and Ca2+. The effect of ion channel blockers on chronic SCI has also been proved. In this Mini‐Review, we provide a comprehensive summary of the effects of ion channel blockers on the natural responses after SCI. Combination therapy is based on the roles of ions and disturbance of their homeostasis in SCI. The effects of ion channel blockers suggest that they have potential in the treatment of SCI, although the complexity of their effects shows that further knowledge is needed before they can be applied clinically. © 2011 Wiley‐Liss, Inc.
Evidence for the Low Dose Dexamethasone Suppression Test to Screen for Cushing's Syndrome—Recommendations for a Protocol for Biochemistry Laboratories

Evidence for the low dose dexamethasone suppression test to screen for Cushing's syndrome-recommendations for a protocol for biochemistry laboratories P J Wood l , J H Barth", D B Freedman. ', L Perry? and B Sheridan' From the 'Department of Chemical Pathology, Duthie Building, Southampton General Hospital. Tremona Road, Southampton SOl6 6YD. 2Leeds General Infirmary, St George Street, Leeds LSI 3EX, 3Luton & Dunstable Hospital. Lewsey Road, Luton. Bedfordshire LU4 ODZ, 4St Batholomew's Hospital, West Smithfield, London EC IA 7BE. 5Royal Victoria Hospital, Grosvenor Road, Belfast BTl2 6BA. UK
Planum temporale asymmetry and models of dominance for language: a reappraisal

A classical developmental model for the left hemisphere specialization for language has been proposed based on the observation of a positive correlation coefficient between the value of an index of asymmetry between the left and right planum temporale surface areas and the size of the right planum temporale. Here, we demonstrate that such correlation is a mathematical artefact and thus should not serve as a basis for establishing models of language hemispheric dominance.
Potency on lowering serum uric acid in gout patients: a pooled analysis of registrative studies comparing febuxostat vs. allopurinol.

OBJECTIVE Hyperuricemia leading to urate crystal formation in tissues represents the pathophysiological mechanism of gout. Guidelines recommend a therapeutic target of serum urate concentration (sUA) <6 mg/dL, or even lower (≤5 mg/dL) in patients with large deposits. We conducted an analysis with the aim to achieve additional insights into the urate-lowering efficacy of two xanthine oxidase inhibitors, allopurinol and febuxostat. PATIENTS AND METHODS This was a pooled analysis of phase III trials on allopurinol and febuxostat, including 4101 patients with gout and hyperuricemia. The efficacy outcomes were: mean reduction of sUA concentration from baseline; number of patients with target sUA levels (<6.0 mg/dL or ≤5 mgdL); time to reach target sUA levels. RESULTS Three registrative, phase III, randomized, multicenter, placebo-controlled/allopurinol-controlled trials assessing the efficacy of febuxostat, were included. The mean reduction of sUA concentration with any dose of febuxostat was higher (-2.92±2.87 mg/dL; -27%), with respect to placebo- (-0.62±1.84 mg/dL; -5%) and allopurinol-pooled groups (-2.41±2.20 mg/dL; -24%). Moreover, febuxostat showed a higher probability to achieve the recommended target sUA concentration than allopurinol [odds ratio: 2.43 (95% CI: 2.119-2.789) and 4.05 (95% CI: 3.41-4.82) for sUA levels <6 mg/dL and ≤5 mg/dL, respectively]. Patients on any-dose febuxostat reached target sUA faster than allopurinol-treated patients (86.04±71.47 vs. 98.76±70.88 days and 52.08±49.97 vs. 90.42±68.03 days for reaching sUA levels <6 mg/dL and ≤5 mg/dL, respectively; p <0.001 for both comparisons). CONCLUSIONS In patients with gout and hyperuricemia, febuxostat was significantly more effective and faster than allopurinol in obtaining the recommended target sUA levels, which were reached by a higher number of patients. Therefore, febuxostat was confirmed as an effective option for the treatment of hyperuricemia in gout.
Some Non-Parametric Identification Results using Timing and Information Set Assumptions

A recent empirical literature on topics such as production function and demand estimation has addressed potential endogeneity problems through use of a combination of timing assumptions on when endogenous variables are chosen by agents, information set assumptions regarding what unobservables are in agents’information sets at various points in time, and Markov assumptions on the unobservable term. This literature has generally relied on parametric assumptions on the primary structural function of interest (e.g. the production function, the demand function). We consider the application of these identifying assumptions in a non-parametric context, and show how the results of Matzkin (2004) and Imbens and Newey (2009) can be applied to show non-parametric identification of the structural function, assuming a scalar unobservable term. We apply the identification argument in a production function context, showing significant non-Hicksian neutral aspects of productivity shocks across three Chilean datasets.
Study of the heterogeneous impact of product-harm events : findings and implications

Though the impact of product-harm events on brands has widely been documented, several interesting questions concerning the impact’s heterogeneity still remain: (1) What is behind the difference of the impact of a product-harm event on different brands? (2) What explains the difference of the impact of a product-harm event on different products under the same umbrella brand? (3) How does the impact of a product-harm event on consumers vary along with the extent to which the focal category is necessary to them? (4) If there is any difference between the impact of product-harm events of different natures (an officially confirmed crisis vs. an unverified rumor), what would it be and what explains it? We use a quasi-experimental approach and design three quantitative studies based on a Nielsen dataset on the Infant Milk Formula category covering sales on all hypermarkets in Shanghai, China between 2008 and 2009 when a product-harm crisis and a product-harm rumor happened successively. We address these questions and propose that those differences can be explained by consumers’ high product-quality uncertainty and their reliance on different information to infer products’ quality after a product-harm crisis or a product-harm rumor. We obtain several findings: (1) The differential impact of a product-harm event on different brands can be explained by several kinds of information that effectively signal brands’ quality; (2) Price-Quality cue largely explains the differential impact on products under the same umbrella brand but not the differential impact on brands; (3) The degree of consumers’ reliance on product quality signals is moderated by the extent to which the focal category is necessary to them; (4) A product-harm crisis and a product-harm rumor can differ not only in terms of the degree of impact, but what is more important, in terms of different product quality signals that consumers would rely on.
Investor reactions to news about firms listed on the Ghana Stock Exchange

The Ghana Stock Exchange has received a lot of attention in recent years. Some research done concerning the GSE conclude that the market is inefficient. Behavioural Finance has been used to explain the aggregate stock market, highlighting irrational decision making. Directly related to the field of Behavioural Finance, this research presents a study into how individual investors react to news on the GSE and the reasons why they react in the ways they do. A descriptive study was done, using interviews and open-ended questionnaires to gather data from individual stock owners as well as some brokerage houses. It was found out that the response to new information on the GSE is fairly rapid. Findings showed that investors react more rapidly to negative news than to positive news. The type of information that respondents admit would cause them to withdraw their investments are mainly news of fraud and financial distress. However, some investors are immune to news, because of the issue of single-sided market orders which makes it difficult for them to react to news and trade the way they want. It is recommended that brokerage houses, investments banking firms and entrepreneurs take advantage of the insufficient or non-existence of market makers, provide such services and help make the stock market more liquid.
Whole-blood folate values in subjects with different methylenetetrahydrofolate reductase genotypes: differences between the radioassay and microbiological assays.

Traditionally, serum and erythrocyte folate were analyzed by microbiological assay (1). Because of the original technical difficulty of such assays, more and more laboratories switched over to the radiometric competitive binding assays (radioassays) as they became available. However, it was subsequently found that these newer assays were problematic, particularly with respect to erythrocyte folate estimates (2). These difficulties are said to have been corrected in the newer versions of the radioassay, and it is now believed that both assays are measuring similar folates, albeit by a different principle, and that the assays give equivalent results (3). The C677T genetic variant results in a thermolabile and less active form of the folate-dependent enzyme 5,10-methylenetetrahydrofolate reductase and has a homozygous prevalence of between 5% and 15% depending on the population studied (4). This variant is of interest clinically because it has been found to be more prevalent in people with neural tube defects (4)(5)(6) and also in those with increased plasma homocysteine, …
Coexisting ferromagnetism and superconductivity in hybrid rutheno-cuprate superconductors

We report the observation of microscopically coexisting ferromagnetism and superconductivity in a hybrid ruthenocuprate RuSr/sub 2/GdCu/sub 2/O/sub 8/, with T/sub c//spl les/40 K. By means of various substituents it is established that the superconductivity originates in the CuO/sub 2/ planes and the ferromagnetism in the RuO/sub 2/ planes, as expected. Muon spin relaxation measurements show that the ferromagnetism, with Curie temperature T/sub M/=132 K, is microscopically uniform and originates from the entire sample bulk. This is probably the first confirmed example of uniform microscopic coexistence of superconductivity and atomic ferromagnetism. The material is determined from thermopower measurements to be an underdoped cuprate with a projected T/sub c,max/=90-100 K, typical of a two-layer cuprate. The oxygen isotope effect exponent of /spl alpha//sub Tc/=1.7 is the largest observed in the high-T/sub c/ cuprates. These materials are expected to provide a rich source of new physics and applications.
Smart Specialization Policy in the EU: Relatedness, Knowledge Complexity and Regional Diversification

Smart specialization has become a hallmark of the EU's Cohesion Policy. Envisaged as a bottom-up initiative identifying local knowledge cores and associated competitive advantages, the operationalization of smart specialization has been rather limited, as a coherent set of analytical tools to guide the policy directives remains elusive. To tackle the weak underpinning of smart specialization policy, we propose a policy framework around the concepts of relatedness and knowledge complexity. We use EPO patent data to provide evidence on how EU regions develop new technologies in the period 1990-2009. We find that diversifying into more complex technologies is highly attractive but difficult for EU regions to accomplish. Regions can overcome this diversification dilemma by developing new complex technologies that build on local related capabilities. We use these findings to construct a policy framework for smart specialization that highlights the potential risks and rewards for regions of adopting competing diversification strategies. We show how potential costs of alternative strategies in regions may be assessed by making use of the relatedness concept, and how potential benefits of various smart specialization strategies can be derived from estimates of the complexity of technologies. A series of case-studies of different types of regions illustrate the utility of this policy framework.
SPARQL Rewriting for Query Mediation over Mapped Ontologies

In the recent years establishing interoperability and supporting data integration has become a major research challenge for the web of data. Uniform information access of heterogeneous sources is of major importance for Semantic Web applications and end users. We describe a methodology for SPARQL query mediation over federated OWL/ RDF knowledge bases. The query mediation exploits mappings between semantically related entities of the global ontology and the local ontologies. A very rich set of mappings, based on Description Logic semantics, is supported. The SPARQL queries that are posed over the global ontology are decomposed, rewritten, and then submitted to the federated sources. The rewritten SPARQL queries are locally evaluated and the results are returned to the mediator. We describe the formal modeling of executable mappings (i.e. mappings that can be used in SPARQL query rewriting), as well as the theoretic and implementation aspects of SPARQL query rewriting. Finally we describe the implementation of a system supporting the mediation process.
Spontaneous Vertebral Artery Dissection Mimicking Cluster Headache

Trigeminal autonomic cephalalgias (TACs) are characterized by severe, strictly unilateral pain in the territory of the distribution of the trigeminal nerve in association with autonomic manifestations (1). The International Headache Society (IHS) classification divides strictly unilateral headaches into three groups: cluster headache (CH), episodic and chronic paroxysmal hemicrania (PH), and shortlasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (1). Symptomatic TACs are not common. However, they have been reported in association with the lesions of the sellar or parasellar structures, internal carotid artery dissection and vertebro-basilar artery diseases (1, 2). As for the disorders involving the vertebral artery, a case of a vertebral artery aneurysm and some cases of vertebral artery dissections (VADs) with lateral medullary infarctions have been reported (3–6). To the best of our knowledge, there has not been any case report of VAD without infarction that was manifested by cluster-like headache. We describe here a case of a spontaneous VAD that presented with cluster-like headache without other neurological manifestations.
Analysis of the genome of an endogenous, ecotropic retrovirus of the AKR strain of mice: micromethod for detailed characterization of high-molecular-weight RNA

A detailed characterization of the genome of an endogenous, ecotropic type C virus, the Akv virus, is presented. Approximately 100 RNase T1-resistant oligonucleotides characteristic of the Akv genome were identified by two-dimensional gel electrophoresis, and the complete nucleotide sequence is presented for 75 of these oligonucleotides. A correspondence between the sequence of some of these oligonucleotides and the amino acid sequence of some virus-coded gag gene proteins is reported. For this study we developed methods suitable for the analysis of high-molecular-weight RNA species in nanogram quantities. The in vitro labeling procedures used here led to uniform labeling of the unique oligonucleotides.
Collaboration In Implementing Problem Based Learning For Nursing Education

Background: Problem based learning is advocate as teaching strategy for development of the 21st century health care practitioners. Collaborative partnerships are much-touted values in organizational life today Purpose: To explore and describe the perceptions of nurse educators and manager on collaboration in implementing PBL in nursing education in South African context Methodology: An exploratory sequential mixed method was used to collect data from purposively recruited participants from three of the five South African universities implementing PBL in nursing education and three North-West Provincial hospitals where PBL students are place for clinical learning. Ethical clearance certificate is NWU-00033-11-A9 Results: Both qualitative and quantitative data indicated the need for various types of collaboration; benefits of collaboration to staff, students, organizations and health care users; factors to successful collaboration in implementing PBL Conclusions: Successful implementation of PBL can be achieved through collaboration of clinical spaces. The strategic management and leadership should be committed to the collaboration by offering support and commitment of time, energy and resources. Recommendations For practice, the strategic management and leadership should be committed to the collaboration by offering support, commitment of time, energy and resources. Effective communication should be to promote participation in the collaboration. Further research on collaboration in implementing PBL at different levels of operations; cultural influences on collaboration; criteria to assess effectiveness of collaboration is necessary.
Association of class I HLA antigens with the clinical manifestations of Turkish patients with Behçet's disease

Summary Genetic factors appear to be important in the pathogenesis of Behçet's disease. Although it is known to be strongly associated with HLA‐B51, the association of HLA class I antigens with specific clinical findings of the disease has not been studied extensively and the few studies are conflicting. The aim of this study was to investigate the association of HLA class I alleles with the manifestations of Behçet's disease in Turkish patients. Eighty‐five patients with Behçet's disease were typed for HLA‐A, B, and C antigens with the serologic, standard microlymphocytotoxicity technique. Possible associations of the HLA complex with clinical findings of Behçet's disease were examined. Statistically significant findings are as follows (P < 0.05): increased HLA‐B51 and decreased HLA‐B35 frequency in patients with thrombophlebitis, increased HLA‐A29 and decreased HLA‐Bw6 frequency in patients with ocular involvement, decreased HLA‐Cw2 frequency in patients with erythema nodosum, and decreased HLA‐Cw7 frequency in patients with genital ulceration. Of particular note, the results of this study suggest that the presence of HLA‐B51 and the absence of HLA‐B35 can be regarded as laboratory risk factors of venous thrombosis in patients with Behçet's disease.
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI KEPUASAN PENGGUNA LAYANAN E-GOVERNMENT Studi Kasus Pada Modul Penerimaan Negara Generasi 2

This research aims to identify the factors that determine customer satisfaction of e-government services. Based on theory and relevant previous research, five hypothesis are formulated, which contain five independent variables, security and privacy, trust, accessibility, awareness of public services, and quality of public services, and one dependent variables, customer satisfaction. Data used in this research is primary data collected through questionnaire distributed to 90 treasurer or finance staff as institution taxpayer in Blitar State Treasury Authority’s precinct. Based on multiple linear regression, trust, accessibility, and quality of public services are significantly influence customer satisfaction. These findings may utilized by Ministry/Institutions to unveil the key factors in developing e-government which are compatible with citizens’ needs and desire as the public service customer.
e-Publications@Marquette e-Publications@Marquette

Objectives: The purpose of this study was to describe the patient experience of communication during mechanical ventilation. Research methodology: This descriptive study is a secondary analysis of data collected to study the relationship between sedation and the MV patients’ recall of the ICU . Interviews, conducted after extubation, included the Intensive Care Experience Questionnaire. Data were analysed with Spearman correlation coefficients ( r s ) and content analysis. Setting: Participants were recruited from a medical-surgical intensive care unit in the Midwest United States.