Miracle-dz/UniFAR-FTUs huggingface dataset:
Structuring warehouse management : Exploring the fit between warehouse characteristics and warehouse planning and control structure, and its effect on warehouse performance

markdownabstractAbstract This dissertation studies the management processes that plan, control, and optimize warehouse operations. The inventory in warehouses decouples supply from demand. As such, economies of scale can be achieved in production, purchasing, and transport. As warehouses become more and more vital for the success of many companies, they are facing increasing demands with respect to costs, productivity, and customer service. At the same time, warehouse operations have become more complex due to developments such as value added services, e-fulfillment, and up-scaling warehouses. Consequently, planning, controlling, and optimizing warehouse operations, defined as warehouse management in this dissertation, have become a distinguishing factor for supply chain performance. This dissertation explores warehouse management by studying the effects of the characteristics of a warehouse (i.e., context) on the structure (i.e., design) of warehouse management. In addition, the match (i.e., fit) between characteristics and structure is researched as an important driver of warehouse performance. By conducting empirical research using a multiple case study and a survey study, an overall theoretical model on structuring high performance warehouse management has been developed.
Biochemical alterations induced by the acute exposure to combination of chlorpyrifos and lead in Wistar rats.

Chlorpyrifos, a well known organophosphorus insecticide and heavy metal lead, was challenged to Wistar rats to study their interactive effects on biochemical parameters (clinical pathology) after acute exposure via oral gavaging. Hematology and clinical chemistry parameters were estimated after 14 days of exposure. In addition, serum butryl and RBC cholinesterase was estimated on days 3 rd and 15 th of experimentation. The study was conducted using two different dose levels of chlorpyrifos and lead acetate and grouped into seven groups. The parameters of hematology and serum chemistry were analysed through automatic analyzers. No treatment related or interactive effects were noticed in hematology values except for the reduced RBC, Hb content and HCT values in lead treated animals at 1000mg/kg. A significant decrease in both serum and RBC cholinesterase enzymes were noticed in animals treated with chlorpyrifos at 50 mg/kg and in combination group (chlorpyrifos 50 + lead 1000 mg/kg), and increased inhibition along with delayed recovery was observed in the animals of combination group (i.e., chlorpyrifos plus lead). Chlorpyrifos in presence of lead increases the inhibition of both serum and RBC cholinesterase enzymes. The long lasting or persistence effects of CPF along with and lead may result in impaired cognitive functions of brain considering the role of cholinesterases in neuronal architecture of brain and other normal functioning of nervous system. Therefore, simultaneous exposure to a combination of chlorpyrifos and lead is considered to be more dangerous than to an exposure of either alone. In addition, serum chemistry revealed changes in concentrations of glucose and sodium owing to lead treatment.
On Equal Terms Working With Disabled People

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The prevalence of TT virus and GB virus C/hepatitis G virus infection in individuals with raised liver enzymes but without HBV or HCV infection in Taiwan

The prevalence of TT virus (TTV) and GB virus-C/hepatitis G virus (GBV-C/HGV) infection and the association with raised liver function tests in 546 Taiwanese with negative HBsAg, anti-HCV and HCV RNA was elucidated. They were tested for serum alanine aminotransferase (ALT), GBV-C/HGV RNA, anti-envelope protein 2 antibody (anti-E2) and TTV DNA. Direct sequencing and phylogenetic analyses were performed on 58 isolates for TTV genotype determination. The prevalence of TTV DNA, GBV-C/HGV RNA, anti-E2 and over all GBV-C/HGV exposure was 24.9, 3.4, 8.2 and 11.1%, respectively. Using uni- and multi-variate analyses, male gender and TTV viremia were associated significantly with raised ALT values. Sixty-nine percent of TTV isolates were deduced to be TTV genotype 1 and they had significantly lower mean age than genotype non-1 isolates. In the population, raised ALT may be related to male gender and be attributable to TTV infection but not to GBV-C/HGV among individuals with no evidence of current HBV and HCV infection. TTV genotype 1 is the most prevalent genotype and associated with younger age.
Parasite-Induced Th2 Polarization Is Associated with Down-Regulated Dendritic Cell Responsiveness to Th1 Stimuli and a Transient Delay in T Lymphocyte Cycling

The nature of the signals that bias Th effector choice is still not completely understood. Using parasite extracts from pathogens known to induce polarized Th1 or Th2 responses and an in vitro experimental model for priming murine CD4+ cells, we demonstrated that splenic dendritic cells (DC), but not B cells, promote Th1/Th2 differentiation of naive CD4+ lymphocytes. Th polarization in this system was found not to depend on DC secretion of the polarizing cytokines IL-12/IL-4, but instead correlated with distinct states of DC activation induced by the different parasite preparations. As expected, conditioning of DC for Th1 development was associated with up-regulation of costimulatory molecules and enhanced chemokine production and required intact MyD88 signaling. In contrast, conditioning of DC for Th2 differentiation correlated with down-regulation of many of the same functions and was MyD88 independent. This dampened DC activation was accompanied in the cocultures by a reduction in the frequency of CD4+ lymphocytes exiting the first division of the cell cycle. When the latter was mimicked by drug-induced arrest of peptide-primed CD4+ cells after the S phase of the first cycle, a marked Th2 polarization was also observed. Together, these findings suggest that the emergence of IL-4-producing CD4+ lymphocytes results from a suppression in DC function leading to a temporary delay in initial T cell cycling.
Oral health status of children with type 1 diabetes: a comparative study

Abstract Background: The aim of this study was to compare the oral health status of children with type 1 diabetes and healthy controls. Methods: This comparative study involved 64 children, 32 children with type 1 diabetes and 32 age- and gender-matched controls. Oral health examination was conducted using WHO criteria. Dental caries experience was recorded using DMFT/dmft index and periodontal parameters were assessed using plaque, gingivitis, gingival bleeding and calculus indexes. Dental caries and periodontal parameters between the two groups were compared using the Mann-Whitney U-test. Results: Children with diabetes exhibited significantly greater plaque deposits (p=0.01) and a higher mean plaque index (p<0.01), when compared to healthy subjects. No significant difference in DMFT and dmft scores, mean bleeding index, calculus index and gingival index was found between the two groups. Conclusions: Children with type 1 diabetes had a poor oral health status with greater plaque accumulation than children without diabetes.
Board Governance and Performance: An Exploratory Study of Malaysian Cooperative Organizations

Cooperatives are expected to help generate economic growth; become competitive business entities; and remain as effective self-help organizations while upholding sensitivity towards the environment. However, cooperatives like their business cousins in the public corporations are plagued with governance issues (Shaw, 2006). This has prompted studies to isolate the probable causes of their predicament. The issue of corporate governance of cooperatives has begun to become mainstream in research, and conventional wisdom dictates that governance procedures and processes that abound in the corporate world can prudently be applicable in the governance of cooperatives (Cornforth, 2004). In a cooperative, the Board of Directors plays a pivotal role in safeguarding the collective interest of the members (Jussila, Goel, & Tuominen, 2012). The Board of Directors needs to demonstrate adequate and effective monitoring of the organizations they are helming. This paper examines the role of Board of Directors as custodian against financial fiasco in cooperatives organizations. This study focuses on the association of the size of Board of Directors of cooperatives and the frequency of board meetings with performance. Outcomes from the study indicated both the size of the board and the frequency of board meetings have no relationship with performance of cooperatives organizations in Malaysia. The results suggest that the board of directors may no longer be effective in managing the cooperatives towards achieving their members' objectives. Various literatures supported this finding. This result indicates that governance of cooperatives is in dire need of revision to increase its effectiveness.
Single crystal targets may improve soft-tissue contrast in megavoltage imaging by means of coherent bremsstrahlung

Coherent bremsstrahlung denotes the process of bremsstrahlung emission by electrons traversing a single crystal, causing prominent peaks in the resulting photon spectra at low energies. While this phenomenon has been known for decades, little attempt has been made to exploit its potential for megavoltage imaging, where the quality of images is affected by low contrast due to the lack of sufficient photons at the energy range suited for diagnostic purposes. We provide a theoretical foundation of coherent bremsstrahlung in the first-order Born approximation without confinement to high energies. Based on this theory, first evidence is given that diamond crystals are capable of boosting the amount of diagnostic photons by about 10–20%. It is shown that this behaviour is largely conserved for polychromatic electrons hitting thick targets, where multiple scattering dominates the energy distribution of the emitted photons.
Stable Histone Deacetylase Complexes Distinguished by the Presence of SANT Domain Proteins CoREST/kiaa0071 and Mta-L1*

Human histone deacetylases I (HDAC1) and II (HDAC2) are homologous proteins (84% identity) that catalyze release of acetyl groups from modified N-terminal lysines of core histones. Histone deacetylation is correlated with both transient and persistent states of transcriptional inactivity (i.e.silencing) in many eukaryotes. In this study, we analyzed complexes containing HDAC1 and HDAC2 to identify the proteins most stably associated with these deacetylases. Complex cI (9.5 S) contained transcriptional corepressor CoREST/kiaa0071 and a protein homologous to FAD-dependent oxidoreductases, kiaa0601. Complex cII (15 S) contained ≥15 proteins, including CHD3/4 (Mi-2), Mta-L1, RbAp48/46, and MBD3, characteristic of vertebrate nucleosome-remodeling complexes. Under native conditions, cI and cII may contain HDAC1, HDAC2 or both; these can be dissociated to cI and cII core complexes containing only HDAC1 or HDAC2. The mCpG-binding protein MBD2 was associated only with the HDAC1 cII core complex. A model is proposed in which HDAC1 core complexes can be targeted to methylated DNA via MBD2 with recruitment of HDAC2 occurring through formation of HDAC1/2 cII dimers. We note that the cI component CoREST/kiaa0071 and the cII component Mta-L1 share a region of homology that includes a SANT domain; this domain may play a role in complex assembly.
Does Total Quality Management Affect the Performance of Small and Medium Enterprises? A Case of Manufacturing SMEs in Ghana

The paper examines the relationship between total quality management (TQM) practices of small and medium enterprises (SMEs) and the performance and profitability of these businesses in Ghana. With the use of a mixed research method consisting of descriptive and inferential statistics the researchers found that differences exist between SMEs in relation to managerial education level, TQM awareness, managerial commitment to TQM principles of continuous improvement, use of new technology, putting the customer first, effective supervision and enforcement of quality practices. The study also shows a statistically significant association between the implementation of TQM and the SMEs’ financial and organisational performance. The implication of the findings is that the government of Ghana should pursue policies aimed at encouraging training and improving the managerial skills of SME owner/managers as well as creating the enabling environment for the development of improved modern technologies to transform the business processes of these vital industries. The Ghana Standards Board must also sit up and enforce quality regimes to ensure goods and services produced meet international standards.
Formation of the Giant Planets by Concurrent Accretion of Solids and Gas

New numerical simulations of the formation of the giant of the second phase. planets are presented, in which for the first time both the gas and The actual rates at which the giant planets accreted small planetesimal accretion rates are calculated in a self-consistent, planetesimals is probably intermediate between the constant interactive fashion. The simulations combine three elements: rates assumed in most previous studies and the highly variable (1) three-body accretion cross sections of solids onto an isolated rates used here. Within the context of the adopted model of planetary embryo, (2) a stellar evolution code for the planet’s planetesimal accretion, the joint constraints of the time scale gaseous envelope, and (3) a planetesimal dissolution code for dissipation of the solar nebula and the current high-Z masses within the envelope, used to evaluate the planet’s effective of the giant planets lead to estimates of the initial surface capture radius and the energy deposition profile of accreted density (sinit) of planetesimals in the outer region of the solar material. Major assumptions include: The planet is embedded nebula. The results show that sinit P 10 g cm 22 near Jupiter’s in a disk of gas and small planetesimals with locally uniform orbit and that sinit ~ a 22 , where a is the distance from the Sun. initial surface mass density, and planetesimals are not allowed These values are a factor of 3 to 4 times as high as that of to migrate into or out of the planet’s feeding zone. the ‘‘minimum-mass’’ solar nebula at Jupiter’s distance and a All simulations are characterized by three major phases. Dur- factor of 2 to 3 times as high at Saturn’s distance. The estimates ing the first phase, the planet’s mass consists primarily of solid for the formation time of Jupiter and Saturn are 1 to 10 million material. The planetesimal accretion rate, which dominates years, whereas those for Uranus fall in the range 2 to 16 million that of gas, rapidly increases owing to runaway accretion, then years. These estimates follow from the properties of our Solar decreases as the planet’s feeding zone is depleted. During the System and do not necessarily apply to giant planets in other second phase, both solid and gas accretion rates are small planetary systems. © 1996 Academic Press, Inc. and nearly independent of time. The third phase, marked by runaway gas accretion, starts when the solid and gas masses are about equal. It is engendered by a strong positive feedback
The role and limitation of living donor liver transplantation for hepatocellular carcinoma

Liver transplantation for hepatocellular carcinoma (HCC) is restricted by the scarcity of cadaver grafts. Living donor liver transplantation (LDLT) may potentially increase the applicability but its role and limitation are not clear. We studied the outcome of a cohort of 51 patients with unresectable HCC who were accepted on list for both options of deceased donor liver transplantation (DDLT) and LDLT. Twenty‐five of 51 (49%) patients had voluntary living donors (group 1) and 26 did not (group 2). Patients in group 1 were younger, and more often had a MELD score more than 20 or blood group other than O. Twenty‐one patients of group 1 underwent LDLT after a median waiting time of 24 days (range, 2–126 days), but 4 did not because the donors were not suitable (HBsAg‐positive, 2; ABO‐incompatible, 1; liver dysfunction, 1). Of the 30 patients who remained on list, only 6 underwent DDLT after a median waiting time of 344 days (range, 22–1359 days, P < .005). Nineteen died before transplantation and 2 were alive but taken off the list because of disease progression (drop‐out rate, 70%). One patient was alive on list and 2 had undergone transplantation outside Hong Kong. The 1‐, 2‐, 3‐, and 4‐year intention‐to‐treat survival rates were 88%, 76%, 66%, and 66%, respectively, for group 1 and 72%, 46%, 38%, and 31%, respectively, for group 2 (relative risk of death for group 1, 0.35; 95% CI, 0.14 to 0.90; P = .029). In conclusion, although complicated factors such as donor voluntarism and selection criteria limit the role of LDLT for HCC, LDLT allows more patients to undergo early transplantation and results in a better outcome. (Liver Transpl 2004;10:440–447.)
In vitro antimicrobial activity of AH Plus, EndoREZ and Epiphany against microorganisms.

OBJECTIVE The aim of the present study was to evaluate the antimicrobial activity of endodontic sealers against microorganisms. MATERIALS AND METHODS The agar diffusion method was used. A double base layer of Mueller Hinton agar was done. The microorganisms used were: Candida albicans, Enterococcus faecalis, Escherichia coli and Staphylococcus aureus. The wells were obtained by removing a standardized portion of the agar. After the distribution of the sealers, Petri plates were incubated for 24 h. Inhibition halos formed around the wells were measured. RESULTS Epiphany did not show any antimicrobial activity on the tested microorganisms (without inhibition halo). The AH Plus showed the greatest inhibition halo on C. albicans followed by EndoREZ on S. aureus. EndoREZ also showed greater inhibition halo in comparison to AH Plus on E. faecalis and E. coli. CONCLUSION It could be concluded that AH Plus and EndoREZ showed antimicrobial activity against all the tested microorganisms. No antimicrobial activity was observed for Epiphany.
International capital mobility and the taxation of portfolio investments

This paper provides an overview of problems related to the taxation of portfolio investments in an open economy. It starts by outlining empirical results on how taxation affects the household portfolio structure and proceeds by discussing the relevance of international capital mobility in relation to portfolio investments. Then, it describes problems pertaining to the taxation of derivative financial instruments, interest, and dividends.
A three-stage model of requirements elicitation for Web-based information systems

Although requirement elicitation is generally acknowledged to be very important in traditional information systems development (ISD), it does not get enough attention in most Web‐based information systems development (WISD). This paper highlighted the difference between ISD and WISD, and proposed a three‐stage model of user requirements elicitation for Web‐based information systems. This model divides the requirements definition into three stages: initial analysis, key user requirements elicitation and regular user responses. Most current WIS design methodologies consider only initial analysis, and neglect actual users’ requirements. Key user input is emphasized in this model, and social network analysis is proposed as a tool for identifying key users. Requirements analysis for WISD is no longer considered a one‐stop step, but is better regarded as a continuous evolving process. Finally, managerial implications are also provided in this paper.
Dental Amalgam: the Materials

The goal of this presentation is to describe the material as it is used clinically, explain why small quantities of Hg can be released, and suggest ideas for amalgams that do not release mercury. A set amalgam is a dynamic material that undergoes many microstructural changes during clinical use, related to both the elevated temperature and corrosion-prone environment in the mouth and mechanical forces applied to the restoration. Amalgams can be divided roughly into two groups by their copper content: low Cu (traditional) and high Cu. High-Cu amalgams generally perform better clinically, but all amalgams corrode to some extent in the mouth. Some corrosion is deemed to be a positive factor, because corrosion product deposition reduces leakage at the margins of restorations; that is, the restorations are partly self-sealing. One of the reasons cited for the improved clinical performance of high-Cu amalgams over low-Cu amalgams is that the corrosion-prone phase, γ 2, is nearly eliminated in high-Cu amalgams. Future research should involve improvements in the clinical performance of dental amalgams, studies of the mercury release from various types of amalgams and the toxic potential of this exposure, and the development of new amalgam systems that reduce the mercury exposure. Although the longevity of modern amalgams is impressive, it is important for their stability to be increased both clinically and microstructurally. An amalgam should be developed with a stable microstructure that, once set, would not change during clinical use. Microstructural changes lead to clinical deterioration. A stable system would not corrode, and the matrix transformation γ 1 to β1 would be prohibited. The latter effect could be achieved by stabilization of the γ1 phase or development of a system that would form the stable β1 phase during amalgamation. Such a system would simultaneously improve clinical performance and reduce the potential for biological side-effects from its deterioration. Studies of the potential for Hg release should be conducted with proper consideration of the microstructures of amalgam systems and alterations in the structures induced by clinical use. Careful studies are needed of the toxic potential from exposure to these materials as they are used clinically.
Explaining Accounting Policy Practices Under IFRS: The Role of Institutional Factors

We argue and document that persistent institutional factors determine managerial accounting policy practice under IFRS. In an analysis of accounting choice across thirteen European countries, we study both overt and covert choices, aggregating them to measure their impact over income, thereby focusing on firm overall accounting strategy and not only on individual choices. Our results indicate that institutional factors significantly explain the observed heterogeneity in accounting policy practices and that firm characteristics have a smaller role in explaining them. Capital market structure and tax-alignment are particularly important factor in driving accounting practice. Contrary to the recent emphasis on enforcement as a key institutional factor, our evidence indicates it is a second order factor, when controlling for other institutional factors.