Miracle-dz/UniFAR-FTUs huggingface dataset:
Constructive Sobolev gradient preconditioning for semilinear elliptic systems

We present a Sobolev gradient type preconditioning for iterative methods used in solving second order semilinear elliptic systems; the n-tuple of independent Laplacians acts as a preconditioning operator in Sobolev spaces. The theoretical iteration is done at the continuous level, providing a linearization approach that reduces the original problem to a system of linear Poisson equations. The method obtained preserves linear convergence when a polynomial growth of the lower order reaction type terms is involved. For the proof of linear convergence for systems with mixed boundary conditions, we use suitable energy spaces. We use Sobolev embedding estimates in the construction of the exact algorithm. The numerical implementation has focus on a direct and elementary realization, for which a detailed discussion and some examples are given.
Risk factors associated with amblyopia among primary school pupils in Kosofe town, Lagos state, Nigeria

Aim: To investigate the risk factors associated with amblyopia among primary school pupils in Kosofe town, Lagos State, Nigeria. Materials and Methods: A descriptive, cross-sectional, school-based study was conducted, in which a multistage random sampling technique was employed for recruiting the children. Data were collected using self-administered questionnaires by the parents or caregivers and from detailed ocular examinations performed by the investigators. Data analysis was performed using the IBM Statistical Package for Social Sciences software version 20.0. Results: A total of 1702 children participated in the study, with over 90% of the children being aged 4–10 years. Most (78.5%) of the mothers were aged 20–39 years at childbirth, and the mean age was 30.5 ± 7.8 years. Amblyopia was detected in 24 (1.41%) children. Following multivariate logistic regression analysis, children whose mothers had no formal education at childbirth had an 11-fold greater risk of having amblyopia [odds ratios (OR) = 11.25, 95% confidence intervals (95% CI) = 1.25–1.49], while those with birth weight <2500 g were 10 times more likely to have amblyopia at the time of examination (OR = 10.15, 95% CI = 0.70–0.90). In addition, children with a positive family history of crossed eyes had an eightfold greater risk of having amblyopia (OR = 8.14, 95% CI = 0.24–0.46). Conclusion: Mother’s educational qualification at childbirth, low birth weight, and a positive family history of crossed eye were found to be strongly associated with the development of amblyopia.
Frequency of Seizure Types in Patients with Multiple Sclerosis Referred to Ardabil City Hospitals: north-west of Iran

1Department of Neurology, Faculty of Medicine, Ardabil University of Medical Science, Ardabil, Iran 2Anesthesiologist, fellowship of palliative care, Faculty of Medicine, Tabriz University of Medical Science, Tabriz, Iran 3Alavi Clinical Research Development Center, Alavi Hospital, Ardabil University of Medical Science, Ardabil, Iran 4Faculty of Medicine, Ardabil University of Medical Science, Ardabil, Iran
HUBUNGAN TINGKAT PENGETAHUAN DENGAN KETERAMPILAN PETUGAS DALAM PELAKSANAAN TRIAGE DI INSTALASI GAWAT DARURAT RSUD WATES

Background:Triage is the process of determining the priority of patients’ treatment based on these verity of their condition. Triage at the Emergency Room is needed to manage the flow of patients coming to the Emergency Room through the sorting of patients according to their critical condition. Staff doing triage are those who have got certificate of training on the management of emergency patients or Basic Trauma Cardiac Life Support (BTCLS). Staff must have good knowledge in implementing triage. Objectives: To identify knowledge and skills of staff in implementing triage and strength of correlation between level of knowledge with skills of staff in implementing triage. Methods:The studi was descriptive analytic with crossectional approach. Samples were purposively selected, consisting of 20 respondents. Data were obtained through questionnaire and observation sheet and analyzed using Kendall Tau. Results:The result of the studi showed the majority of staff had good knowledge (70%) and skills (85%). The result of Kendall Tau test showed score of significance was 0.025 (sig<0.05) with correlation coefficient 0.450 which meant that strength of correlation between level of knowledge with skills in the implementation of triage was average. Conclusion:There was significant correlation between level of knowledge with skills of staff at the Emergency Room of Wates Hospital with average strength of correlation. Keywords:knowledge, skills, triage
What is the contribution of personal information management systems (PIMS) to the Working Model and personal work system of knowledge workers

The thesis reports research into a phenomenon which it calls the personal working model of an individual knowledge worker. The principal conjecture addressed in this thesis is that each of us has a personal working model which is supported by a personal work system enabled by a personal information management system. For some people, these are well defined; for most they are not even explicit. By means of structured self-reflection aided by conceptual knowledge modelling within the context of a process of action learning they can be improved. That personal working model is predicted by Ashby's law of requisite variety and by the good regulator theorem of Conant and Ashby. The latter theorem states that the only good regulator of a system is a model of that system. The thesis and the work it reports result from a systemic approach to identifying the personal information management system and personal work system which together contribute to the personal working model. Starting with abductive conjecture, the author has sought to understand what models are and to explore ways in which those models can themselves be expressed. The thesis shows how a new approach to the conceptual modelling of aspects of the personal knowledge of knowledge worker was designed, built and then used. Similarly, the actual data used by a knowledge worker had to be stored, and for this purpose a personal information management system was also designed. Both these artefacts are evaluated in accordance with principles drawn from the literature of design science research. The research methodology adopted in the first phase of the research now ending also included a relatively novel approach in which the PhD student attempted to observe himself over the last five years of his PhD research – this approach is sometimes called autoethnography. This autoethnographic element is one of a number of methods used within an overall framework grounded by the philosophical approach called critical realism. The work reported in the thesis is initial exploratory research which, it is planned, will continue in empirical action research involving mentored action learning undertaken by professional knowledge workers.
Raddeanin A Induces Apoptosis and Cycle Arrest in Human HCT116 Cells through PI3K/AKT Pathway Regulation In Vitro and In Vivo

This study aimed to investigate the in vitro and in vivo effects of Raddeanin A on apoptosis and the cell cycle in the human colorectal cell line, HCT116, and to explore the possible underlying mechanisms of action. We found the growth inhibition rate gradually increased as the drug concentration increased via the 3-(4,5)-dimethylthiahiazo(-z-y1)-3,5-di-phenytetrazoliumromide (MTT) assay, which indicated that Raddeanin A significantly inhibited the growth of HCT116 cells. Flow cytometry (FCM) showed that Raddeanin A concentration-dependently induced apoptosis in HCT116 cells. In addition, the percentage of cells in the G0/G1 phase was noticeably increased, which indicated that Raddeanin A blocked cell cycle progression in HCT116 cells and caused arrest in the G0/G1 phase. Moreover, the expression of proteins involved in the PI3K/AKT signaling pathway (e.g., p-PI3K and p-AKT) was decreased. The results showed that in vivo revealed that Raddeanin A significantly inhibited tumor growth in an HCT116-xenografted mouse model; apoptotic cells were also detected in the tumor tissue. The expression of the tissue proteins cyclinD1, cyclinE, p-PI3K, and p-AKT was decreased. The above results show that the Raddeanin A exerted a strong antitumor effect in the human colorectal cell line HCT116 both in vitro and in vivo. This effect may be caused by the induction of apoptosis and cycle arrest achieved through PI3K/AKT signaling pathway regulation.
FAKTOR – FAKTOR YANG BERHUBUNGAN DENGAN KEKURANGAN ENERGI KRONIK (KEK) IBU HAMIL DI WILAYAH KERJA PUSKESMAS ROWOSARI SEMARANG

Latar Belakang : Status gizi ibu hamil merupakan salah satu faktor yang dapat mempengaruhi kondisi kehamilan dan kesehatan janin. Proporsi KEK di Jawa Tengah tahun 2015 sebesar 1.836 ibu hamil. Tujuan: Mengetahui faktor risiko yang berhubungan dengan kejadian KEK pada ibu hamil. Metode Penelitian : Analitik observasional dengan desain case control di Rowosari bulan Juni – September 2018 dengan teknik total sampling untuk kelompok kasus dan simple random sampling untuk kelompok kontrol,dengan jumlah sampel yang berhasil terkumpul yaitu 18 kasus dan 58 kontrol. Instrumen berupa kuesioner yang telah diuji validitasnya. Pengambilan data dengan cara wawancara, kemudian analisis hubungan dengan uji statistic Chi square dan uji statistik multivariat dengan regresi logistik. Hasil : Analisis statistik diperoleh jarak kehamilan (p= 0,001, 95% CI= 1,974-24,354, OR= 6,93), status ekonomi (p= 0,012, 95% CI= 1,298-11,888, OR=3,929), dukungan keluarga (p= 0,000, 95%CI= 2,884-38,961, OR= 10,600), asupan zat gizi (p= 0,019,95% CI= 0,093-0,838, OR= 0,279), PHBS (p=0,002, 95%CI= 1,876-61,807, OR= 10,769) memiliki hubungan signifikan terhadap KEK. Sedangkan factor usia (p= 0,173,95% CI= 0,030-2,096,OR= 0,251), pendidikan ibu hamil (p= 0,097,95% CI= 0,831-7,608, OR =2,541),pengetahuan (p= 0,136, 95%CI= 0,759-6,950, OR= 2,296), gravida (p= 0,872, 95%CI= 0,277-2,973,OR= 0,907), pendidikan suami(p= 0,097,95%CI= 0,831-7,608,OR= 2,514), aksesibilitas layanan kesehatan (p= 0,577,95%CI =0,198-2,397,OR= 0,689). Analisis statistik multivariat diperoleh faktor yang paling dominan yaitu asupan zat gizi (p= 60,031, 95%CI= 1,184 – 35,539,OR= 6,488). Kesimpulan :Faktor jarak kehamilan, status ekonomi, dukungan keluarga, asupan zat gizi, dan PHBS memiliki hubungan signifikan dengan KEK. Faktor yang paling dominan penyebab KEK yaitu asupan gizi. Disarankan untuk meningkatkan pengetahuan mengenai KEK Kata kunci: KEK,karakteristik ibu hamil, sosial ekonomi,status gizi, PHBS.
Fall and Spring Applications of Trifluralin and Metribuzin in Fababeans (Vicia faba)

Field experiments were conducted to study the effect of fall and spring pre-plant incorporated applications of trifluralin (α,α,α-tri-fluoro-2,6-dinitro-N,N-dipropyl-p-toluidine) and metribuzin [4-amino-6-tert-butyl-3-(methylthio)-as-triazine-5(4H)-one] alone and in combinations on crop tolerance, seed yield, and weed control in fababeans (Vicia faba L. ‘Diana’). Trifluralin applied either in the fall or the spring resulted in acceptable control of green foxtail [Setaria viridis (L.) Beauv. ] and wild oat (Avena fatua L.) while metribuzin resulted in excellent control of wild mustard [Brassica kaber (DC.) L.C. Wheeler var. pinnatifida (Stokes) L.C. Wheeler]. In 2 out of 3 yr, a tank-mixture of trifluralin plus metribuzin applied in the fall at 1.4 and 0.4 kg/ha, respectively, resulted in significantly larger seed yield than the same combination applied at 1.1 and 0.3 kg/ha in the spring. Although the fall treatments generally resulted in higher seed yields, there was no consistent difference in weed densities between fall and spring applications. In both field and growth room studies, trifluralin reduced the injury to fababeans from metribuzin. A postemergence application of metribuzin in the spring at 0.3 kg/ha following a fall-application of trifluralin resulted in good wild mustard control but caused considerable crop damage. Dinoseb (2-sec-butyl-4,6-dinitrophenol) and bentazon [3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2dioxide] controlled wild mustard effectively with no injury to the crop.
Top Management Team Diversity, Equality, and Innovation: A Multilevel Investigation of the Health Care Industry

The role of women on top management teams (TMTs) is an increasingly important topic for both academics and practitioners. Despite increased attention to gender diversity on TMTs, there remains limited understanding of how gender diversity influences important outcomes of the firm, such as innovation. To this end, I investigate the relationships between two dimensions of TMT diversity—TMT gender diversity and TMT compensation equality—and firm innovation, and consider how TMT size influences these relationships. Using a unique, multilevel, longitudinal sample of publicly traded firms in the U.S. health care industry, I find TMT size to be a key driver in the TMT diversity and firm innovation relationship.
Page Proof Instructions and Queries

Whether pornography contributes to sexual aggression in real life has been the subject of dozens of studies over multiple decades. Nevertheless, scholars have not come to a consensus about whether effects are real. The current meta-analysis examined experimental, correlational, and population studies of the pornography/sexual aggression link dating back from the 1970s to the current time. Methodological weaknesses were very common in this field of research. Nonetheless, evidence did not suggest that nonviolent pornography was associated with sexual aggression. Evidence was particularly weak for longitudinal studies, suggesting an absence of long-term effects. Violent pornography was weakly correlated with sexual aggression, although the current evidence was unable to distinguish between a selection effect as compared to a socialization effect. Studies that employed more best practices tended to provide less evidence for relationships whereas studies with citation bias, an indication of researcher expectancy effects, tended to have higher effect sizes. Population studies suggested that increased availability of pornography is associated with reduced sexual aggression at the population level. More studies with improved practices and preregistration would be welcome.
EVALUATING EFFECT OF PEPPER MINT OIL (Mentha pipreta) AND ITS NANO-FORMULATIONS ON SOME ENZYMATIC ACTIVITIES AND BIONOMICS OF COTTON LEAF WORM Spodoptera littoralis (BOISD.) [

Different formulations of pepper mint oil, i.e. bulk, nano-emulsion and nano-encapsulation were evaluated against 2nd and 4th instar larvae of the cotton leafworm Spodoptera littoralis (Boisd.). Their effects on enzymatic activities and bionomics were also investigated. Transmission Electron Microscopy (TEM) showed that the mean particle size of the prepared nano-emulsion ranged between 20-90nm. The encapsulation efficiency and loaded capacity percentages exhibited that distilled H2O was more suitable than ethanol in preparation of nano-encapsulation particles. Bioassay treatments showed LC50's on 2nd instars larvae were 70.59, 12.23 and 21.72 ppm for pepper mint oil, pepper mint nano-emulsion and loaded nanoemulsion, respectively. While on 4th instars these values were 80.47, 26.14 and 67.69 ppm, respectively. LC90's on 2nd instars were 104.75, 33.97 and 30.14 for pepper mint oil, pepper mint nanoemulsion and loaded nano-emulsion, respectively. While on 4th instars these values were 177.66, 71.37 and 102.29 ppm. Toxicity index and relative potency proved that nano-emulsion was more effective than loaded nano-emulsion, while the bulk preparation was the least effective one. Results of enzymatic activities showed marked effects of the three formulations of mint oil, significant inhibitions were recorded for amylase, invertase, trehalase, protease and alkaline phosphatase, while significant increase in activities of cuticle phenoloxidase and chitinase. Effects of adding the three formulations to artificial diet of 2nd instar showed significant effects of the insect bionomics. Larvae durations, percentage mortalities, were increased as well as larval malformations. Also, pupal duration, percentage pupal mortality and pupal malformation were increased, while pupal weight was decreased. Adults longevity showed insignificant effects, while female fecundity and egg % fertility showed significant responce.
COMPARAÇÃO DAS PROPRIEDADES QUÍMICAS E DO PERFIL LIPÍDICO DAS FARINHAS DE BOCAIUVA (Acrocomia spp.) DESPOLPADA DE FORMA MANUAL E MECÂNICA

A palmeira Acrocomia spp, também conhecida como bocaiuva, tem sido explorada de forma extrativista por agricultores de subsistência que vivem na área de ocorrência, gerando fonte de renda e a valorização dos frutos nativos. A bocaiuva é de difícil despolpa, então este estudo tem como objetivo comparar as propriedades químicas e o perfil lipídico das farinhas de bocaiuva despolpadas de forma manual e mecânica. Foram realizadas as análises químicas: umidade, cinzas, lipídios, proteínas, carboidratos e fibras. Os ácidos graxos foram determinados por cromatografia gasosa. Todos os parâmetros químicos diferiram estatisticamente entre as duas farinhas, exceto os valores de proteínas. Os valores de umidade, cinzas e carboidratos foram superiores na farinha da polpa extraída de forma mecânica. Maiores teores de lipídios, fibras e calorias foram encontrados na farinha de despolpa manual. O perfil de ácidos graxos saturados dos óleos da polpa de bocaiuva extraída pelos diferentes métodos foi o mesmo (23%), dos quais o ácido palmítico foi o componente majoritário. Os ácidos graxos poli- e insaturados reduziram na farinha de extração mecânica. Em conclusão, a farinha de bocaiuva obtida de forma manual apresentou maior valor nutricional, presença de ácidos graxos poli- e insaturados.
Systematic interrogation of the distinct metabolic potential in gut microbiomes of inflammatory bowel disease patients with dysbiosis

The human gut microbiome plays an important role in human health. In order to investigate changes in metabolic activity associated with dysbiotic microbiomes, we retrieved strain-level relative abundances from metagenomics data from a cohort of pediatric Crohn’s Disease patients with and without dysbiosis, and healthy control children to construct a personalized microbiome model for each sample using the AGORA resource of genome-scale gut microbial reconstructions. Subsequently, we systematically profiled each individual microbiome by predicting the quantitative biosynthesis potential for all secreted metabolites as well as the strain-level contributions to each metabolite in each individual microbiome. The predicted fecal metabolomes and strain-metabolite contributions of microbiomes from patients with dysbiosis were distinct from healthy controls and patients without dysbiosis. Finally, we validated the predicted amino acid production profiles against fecal metabolomic measurements. Taken together, we presented an efficient, scalable, tractable computational approach to systematically interrogate the metabolic potential of individual microbiomes.
Evolution of the Palaeotethys in the Eastern Mediterranean: a multi-method approach to unravel the age, provenance and tectonic setting of the Upper Palaeozoic Konya Complex and its Mesozoic cover sequence (south-central Turkey)

ABSTRACT Siliciclastic sediments from the Upper Palaeozoic Konya Complex and its Mesozoic cover were studied by a multi-method approach combining thin-section petrography, bulk-rock geochemistry, mineral chemistry of rutile, and U–Pb geochronology of detrital zircons. Provenance sensitive data of samples from the Upper Palaeozoic Halıcı Formation indicate sediment supply from mainly low- to medium-grade metamorphosed sedimentary rocks of felsic character, while the contribution from volcanic rocks was rare. The detrital zircon record of sediments from the Halıcı Formation documents sediment supply from different sources and excludes a similar provenance. Some samples show great similarities with Palaeozoic sandstones from the cover sequence of the Saharan Metacraton and the Arabian–Nubian Shield, while the other samples indicate a provenance that must be sought in units with a southern Eurasian affinity. The upper limit for sediment deposition in the Halıcı Formation is mostly constrained by Early Palaeozoic zircon populations; however, sediment accumulation in Pennsylvanian–Cisuralian time is more likely, contemporaneously with the Upper Palaeozoic succession on the Karaburun Peninsula (western Turkey). The provenance of sediments from the Upper Triassic Ardıçlı Formation remains enigmatic, but the source should be sought nonetheless in units close to the depositional site. In any case, detrital zircon age spectra and compositional data exclude recycling of underlying rock units (i.e. Halıcı Formation). Overall, our new provenance data reveal great similarities between the Konya Complex and comparable units (Chios, Karaburun) but also highlight distinct differences in terms of sediment composition and provenance.
Economics and Quality of Life in Oncology Clinical Practice

Pharmacoeconomics and outcomes research are two new sciences that are beginning to affect the practice of oncology. As cost awareness in cancer care becomes acute, practicing oncologists must understand how to apply these sciences to their practices. This publication represents the proceedings of the symposium, Economics and Quality of Life in Oncology Clinical Practice, which was held on November 19, 1997, on the occasion of the EORTC meeting during The First European Conference on the Economics of Cancer. The presentations at the symposium provided an overview of some studies that have begun to explore the variety of activities comprising outcomes assessment, and how such data can be used to help deliver high quality patient care in a cost-conscious environment.
Soil Water Content Estimation Using High-Frequency Ground Penetrating Radar

The rapid high-precision and nondestructive determination of shallow soil water content (SWC) is of vital importance to precision agriculture and water resource management. However, the low-frequency ground penetrating radar (GPR) technology currently in use is insufficient for precisely determining the shallow SWC. Therefore, it is essential to develop and use a high-precision detection technology to determine SWC. In this paper, a laboratory study was conducted to evaluate the use of a high-frequency GPR antenna to determine the SWC of loamy sand, clay, and silty loam. We collected soil samples (0–20 cm) of six soil types of loamy sand, clay, and silty loam and used a high-frequency (2-GHz) GPR antenna to determine the SWC. In addition, we obtained GPR data and images as well as characteristic parameters of the electromagnetic spectrum and analyzed the quantitative relationship with SWC. The GPR reflection two-way travel times and the known depths of reflectors were used to calculate the average soil dielectric permittivities above the reflectors and establish a spatial relationship between the soil dielectric permittivity ( ε ) and SWC ( θ ), which was used to estimate the depth-averaged SWC. The results show that the SWC, which affects the attenuation of wave energy and the wave velocity of the GPR signal, is a dominant factor affecting the soil dielectric permittivity. In addition, the conductivity, magnetic soil, soil texture, soil organic matter, and soil temperature have substantial effects on the soil dielectric permittivity, which consequentially affects the prediction of SWC. The correlation coefficients R2 of the “ θ ~ ε ” cubic curve models, which were used to fit the relationships between the soil dielectric permittivity ( ε ) and SWC ( θ ), were greater than 0.89, and the root-mean-square errors were less than 2.9%, which demonstrate that high-frequency GPR technology can be applied to determine shallow SWC under variable hydrological conditions.