Miracle-dz/UniFAR-FTUs huggingface dataset:
Plasma fatty acids, prostaglandin F2alpha metabolite, and reproductive response in postpartum heifers fed rumen bypass fat.

An experiment was conducted to determine whether feeding rumen-protected fatty acids (FA) to postpartum heifers would increase plasma concentrations of linoleic acid and PGF2, metabolite (PGFM), shorten the interval from calving to first increase in plasma concentrations of progesterone (P4), and increase pregnancy rate relative to controls. Hereford x Angus heifers (346 kg) were assigned randomly to treatments containing either lipid or barley supplemented diets for the first 30 d postpartum. Lipid was . 23 kg.heifer(-1). d(-1) of calcium salts of FA (CSFA; n = 20), and an isocaloric amount of barley served as the control (n = 19). Supplements, with . 23 kg of barley as a vehicle, and a basal diet of meadow and alfalfa hays were pen fed to heifers (5/pen). Heifers were bled on alternate days (d1 to 30) and twice weekly (d 30 to 2 wk after first estrus) for RIA of plasma PGFM and P4, respectively. Weight percentage of major FA in plasma on d1 and 7 was determined with gas chromatography. First behavioral estrus was detected by use of intact bulls and confirmed by an increase in plasma P4. On d 7, but not d 1, plasma from heifers fed CSFA had altered proportions of major FA (P < .01), including an increase in linoleic acid compared with those of controls (29.1 vs 25.6% of total FA; SE = .75; P < .01). Analysis of variance of contrast variables revealed an effect of treatment on direction of change in PGFM from d 3 to 5 (P < .01). By d 7 and on d 9, plasma concentrations of PGFM were greater in heifers fed CSFA than in controls (P = .02 and P = .06, respectively). There was no difference in plasma concentration of PGFM between treatments on d 1, 3, 5, 11, 13, and 15 postpartum (P = .80, .17, .52, .82, .46, and .77, respectively). Days to first estrus with ovulation, pregnancy rate, and calving interval were not affected by treatments (P = .58, .52, and .24, respectively). Although supplemental lipid fed to primiparous beef heifers increased plasma levels of linoleic acid and production of PGFM in the early postpartum period, it did not improve the fertility of these heifers in the subsequent breeding season.
A comparison of the CD 4 response to antiretroviral regimens in patients commencing therapy with low CD 4 counts

s of the Eleventh Conference on Retroviruses and Opportunistic Infections, San Francisco, CA, USA. Abstract 550. 42. Staszewski, S. , Gallant, J., Pozniak, A. , et al. (2003). Efficacy and safety of tenofovir df versus stavudine when used in combination with lamivudine and efavirenz in antiretroviral naive patients: 96 week preliminary interim results. In Abstracts of the Tenth International Conference on Retroviruses and Opportunistic Infections, Boston, USA, Poster 564b. CD4 response to antiretrovial regimens 507 D ow naded rom http/academ ic.p.com /jac/article-ct/54/2/503/767433 by gest on 03 M arch 2019
The information content of money in forecasting euro area inflation

This article contributes to the debate on the role of money in monetary policy by analysing the information content of money in forecasting euro-area inflation. We compare the predictive performance within and among various classes of structural and empirical models in a consistent framework using Bayesian and other estimation techniques. We find that money contains relevant information for inflation in some model classes. Money-based New Keynesian Dynamic Stochastic General Equilibrium (DSGE) models and Vector Autoregressions (VARs) incorporating money perform better than their cashless counterparts. But there are also indications that the contribution of money has its limits. The marginal contribution of money to forecasting accuracy is often small, money adds little to dynamic factor models, and it worsens forecasting accuracy of partial equilibrium models. Finally, nonmonetary models dominate monetary models in an all-out horserace.
Inhibition of Human Erythrocyte Glucose 6-Phosphate Dehydrogenase by Cadmium, Nickel and Aluminium

The inhibition of human erythrocyte glucose 6-phosphate dehydrogenase (G6PD) by Cd (II), Al (III) and Ni (II) was studied. The enzyme was partially purified having specific activity of 1.4 U/mg protein. Cadmium inhibited G6PD activity progressively up to 1.5 mM concentration where about 65% of the enzyme activity was lost. The inhibition was uncompetitive and noncompetitive with respect to glucose 6-phosphate and NADP + , respectively. Cd (II) also increased maximum emission spectrum of the intrinsic protein fluorescence. Sulfhydryl compounds such as glutathione (1.2 mM), β-mercaptoethanol (1.2 mM) or dithiothreitol (1.25 mM) protected the enzyme activity against Cd (II) inhibition and restored the native protein fluorescence. The data suggest that sulfhydryl groups are involved in Cd (II) inhibition. The inhibition patterns for Al (III) were mixed type and competitive when NADP + and glucose 6-phosphate were the variable substrates, respectively. The enzyme inhibition by Al (III) was increased as the pH of the incubation mixture decreased indicating that mainly the ionized form of Al (III) abolishes the enzyme activity. The types of the enzyme inhibition by Ni (II) were competitive with respect to NADP + and mixed type when glucose 6-phosphate varied. Ki values of 1.5 mM, 0.039 mM 0.05 mM for Cd (II), Al (III) and Ni (II) were calculated from the slope replots, respectively. The data suggest that direct interaction of these metal ions with human erythrocyte G6PD produces a reversible inhibition of the enzyme and that their toxicity, at least in part, may be due to the inhibition of this enzyme.
A survey of common pathogens in wound in patients at the University of Port Harcourt Teaching Hospital (U.P.T.H), Port Harcourt.

During a 30-month period, January 1996 to June 1998, a total of 2458 wound swab samples were collected, cultured and identified. In descending order of frequency, the organisms isolated include: Staphylococcus aureus (31.60%), Escherichia coli (25.97%), Pseudomonas aeruginosa (21.21%), Klebsiella species (10.82%), Proteus species (8.23%), non-haemolytic streptococci (1.29%), Beta-haemolytic streptococcus (0.43%) and Candida albicans (0.43%). The variation in frequency of the isolates according to sex, age and ward is reported. The antibiotic sensitivity pattern of these isolates is also presented.
STUDI DESKRIPTIF KEPUASAN PERKAWINAN PADA PEREMPUAN YANG MENIKAH DINI

Dewasa ini, banyak perempuan yang memutuskan untuk menikah pada usia dini. Perkawinan dini menimbulkan banyak masalah bagi perempuan yang menjalaninya seperti dalam hal pendidikan, ekonomi, dan kesehatan reproduksi. Hal ini memengaruhi cara pandang perempuan dalam melihat perkawinannya yang disebut sebagai kepuasan perkawinan. Kepuasan perkawinan adalah kesan subjektif individu dalam melihat hubungan perkawinannya. Adanya keterkaitan antara kepuasan perkawinan pada perempuan yang menikah dini mendasari peneliti untuk meneliti lebih lanjut. Tujuan penelitian adalah untuk menggambarkan kepuasan perkawinan pada perempuan yang menikah pada usia dini. Subjek penelitian terdiri atas perempuan berusia 16 hingga 24 tahun yang menikah pada usia 16 hingga 19 tahun. Data diperoleh menggunakan teknik snowball sampling dan pengambilan data menggunakan angket adaptasi Fowers & Olson yaitu Enrich Marital Scale (EMS). Pada penelitian ini ditemukan bahwa kepuasan perkawinan perempuan yang menikah dini terbagi menjadi empat kelompok (rendah (N=3), (N=8), tinggi (N=24), dan sangat tinggi (N=40). Hasil penelitian menunjukkan bahwa dari tiap kelompok kepuasan perkawinan terdapat lima persamaan antar kelompok dan delapan perbedaan yang menjadi karakteristik tiap kelompok. Kelima persamaannya dalam hal agama, dampak perkawinan dalam hal ekonomi, kesehatan, emosional, dan sosial. Kedelapan perbedaan antar kelompok kepuasan perkawinan ini yaitu dalam hal jumlah anak, tempat tinggal, usia kawin, pendapatan suami subjek per bulan, alasan perkawinan, usia perkawinan, dan dampak perkawinan dalam hal fisik dan pendidikan.
Quantitative Analysis of Lead, Cadmium and Chromium found in Selected Fish marketed in Metro Manila, Philippines

Heavy metals are considered as a major pollutant causing environmental cytotoxic, mutagenic and carcinogenic effects in animals and aquatic organisms. Pollution caused by these substances can arise from many sources and the major problem associated with its persistence is its potential for bioaccumulation. Heavy metals such as lead (Pb), cadmium (Cd) and chromium (Cr) are the most common toxicant that can be found in the marine environment including fish. Fish is a common table food consumed by humans for protein nourishment and its use to study heavy metal contamination would benefit majority of individuals living in a country surrounded by bodies of water, such as the Philippines. The study aims to analyze the presence of lead, cadmium and chromium using qualitative and quantitative tests in the head, meat and internals of selected fish samples sold in wet markets located at Metro Manila, Philippines. Quantitative analysis confirmed the presence of lead, cadmium and chromium in all fish samples. Results were reinforced by the Flame Atomic Absorbance Spectroscopy, wherein most of the fish samples exceeded the standard limits set by US-EPA and FDA for lead, cadmium and chromium i.e. 0.5, 0.05 and 0.1 ppm respectively. Single factor ANOVA have shown that there is no significance among the levels of lead, cadmium and chromium with p values of 0.3679, 0.8858 and 0.9593 respectively in the head, meat and internal organs of the fish samples. Therefore, a person will acquire the same amount and effect of the heavy metals regardless of the part of the fish to be consumed. This study would be useful for the creation of guidelines to protect the public from the harmful effects of the toxicants present in fish that is consumed by the public.
In proven deep vein thrombosis, a low positive D-Dimer score is a strong negative predictor for associated malignancy

Summary D-Dimer measurements are being increasingly used for negative prediction of deep vein thrombosis (DVT). At our institution, clinical score, D-Dimer assay, plethysmography and, if necessary, Doppler ultrasound are used to secure the diagnosis. We collected the data from 100 consecutive patients proven to have DVT. We examined their medical case notes at diagnosis for concurrent clinical conditions and one year later to look for documented evidence of malignancy. Twenty-two of the 66 patients with D-Dimers greater than 1000 ng/ml were diagnosed with a cancer compared with only 2 of the 34 patients with a presenting D-Dimer score of less than 1000 ng/ml. We propose that a D-Dimer score of less than 1000 ng/ml in proven DVT is a strong negative predictor for malignancy (p = 0.0025).
Mesh Cage Reconstruction With Autologous Cancellous Graft in Anterior Cervical Discectomy and Fusion

Study Design Retrospective case series. Objective To present the technique and results of anterior cervical discectomy and fusion (ACDF) by using mesh cage reconstruction with autologous cancellous bone graft. Background Since the initial ACDF description by Bailey and Badgley, a variety of grafting techniques have been proposed. The primary disadvantage of autologous bone grafting is donor site pain when compared with allograft. However, autologous bone graft still remains the standard and cancellous bone retrieval through a cortical window minimizes subperiosteal stripping. This may improve donor site morbidity while providing the advantages of autologous bone graft. Methods Thirty-seven patients who had undergone ACDF with cancellous bone graft by using mesh cages and anterior plating with at least 6 months follow-up were reviewed. All patients had autologous cancellous bone graft harvested through a cortical window with limited subperiosteal striping. Bone graft was then packed into and around a titanium mesh cage that furnishes structural support. Results The principal diagnosis was radiculopathy in 30 patients, myeloradiculopathy in 2 patients, instability in 3 patients, and kyphosis in 2 patients. Sixty-four levels were fused: one 4-level fusion, eight 3-level fusions, eight 2-level fusions, and twenty 1-level fusions. All patients demonstrated improved neurologic function and resolution of preoperative pain postoperatively. The donor site for cancellous bone was the iliac crest in 33 patients and the manubrium in 4 patients. Perioperative donor site pain was absent in 35 of 38 patients by 6 weeks with resolution of donor site pain by 3 months in all patients. At most recent follow-up, no patients had donor site pain, no instrumentation failure, and no wound complications. Sixty-three of 64 (98.4%) of cervical segments fused. One pseudoarthrosis occurred in an attempted 4-level fusion, which fused after a second operation. Conclusions Autologous bone grafting with mesh cage reconstruction is an acceptable alternative to autologous tricortical structural graft or allograft with reduced donor site pain and excellent biologic arthrodesis.
Bobath or Motor Relearning Programme? A follow-up one and four years post stroke

Objective: The purpose of this follow-up one and four years post stroke was to find out whether the initial physiotherapy approach had had any long-term effects on mortality, motor function, postural control, activities of daily living, life quality, follow-up from community services and living conditions. Design: A randomized controlled trial of first time ever stroke patients. Group 1 (n = 33) and group 2 (n = 28) had initial physiotherapy according to the Motor Relearning Programme and Bobath, respectively. Main outcome measures: The Motor Assessment Scale (MAS), the Sødring Motor Evaluation Scale (SMES), the Barthel ADL Index, the Nottingham Health Profile (NHP) and Berg Balance Scale were used. The following parameters were also registered: incidence of new strokes, other diseases, use of assistive devices, the patient's accommodation and use of services from the community. Results: The mortality rates were similar in the two groups. In both groups the motor function, postural control and ADL had decreased rapidly, leaving many of the patients dependent and with a high risk of falling. Life quality had increased compared to the acute stage, but was still low in comparison with healthy persons. Patients in both groups lived at home, but were dependent on help from relatives and community services. Physiotherapy as follow-up service was seldom used. The initial physiotherapy approach did not seem to have a major in‘uence on the patients' ability to cope in the long term. Conclusion: This follow-up at one and four years post stroke showed no major in‘uence of two different initial physiotherapy regimens on long-term function. The study confirmed a rapid deterioration of ADL and motor function and an increased dependence on relatives. The study reveals a gap between the intense treatment in the acute phase and little or no follow-up of physiotherapy treatment or other rehabilitation activities later.
Glucosamine‐Induced Sp1 O‐GlcNAcylation Ameliorates Hypoxia‐Induced SGLT Dysfunction in Primary Cultured Renal Proximal Tubule Cells

The aim of this study is to determine whether GlcN could recover the endoplasmic reticulum (ER) stress‐induced dysfunction of Na+/glucose cotransporter (SGLT) in renal proximal tubule cells (PTCs) under hypoxia. With the rabbit model, the renal ischemia induced tubulointerstitial abnormalities and decreased SGLTs expression in tubular brush‐border, which were recovered by GlcN. Thus, the protective mechanism of GlcN against renal ischemia was being examined by using PTCs. Hypoxia decreased the level of protein O‐GlcNAc and the expression of O‐GlcNAc transferase (OGT) while increased O‐GlcNAcase (OGA) and these were reversed by GlcN. Hypoxia also decreased the expression of SGLTs (SGLT1 and 2) and [14C]‐α‐methyl‐D‐glucopyranoside (α‐MG) uptake which were recovered by GlcN and PUGNAc (OGA inhibitor). Hypoxia enhanced reactive oxygen species (ROS) and then ER stress proteins, glucose‐regulated protein 78 (GRP78), and C/EBP‐homologous protein (CHOP). However, the expression of GRP78 increased till 6 h and then decreased whereas CHOP increased gradually. Moreover, decreased GRP78 and increased CHOP were reversed by NAC (antioxidant) and GlcN. GlcN ameliorated hypoxia‐induced decrease of O‐GlcNAc modification of Sp1 but OGT or Sp1 siRNAs blocked the recovery effect of GlcN on SGLT expression and α‐MG uptake. In addition, hypoxia‐decreased GRP78 and HIF‐1α expression was reversed by GlcN but OGT siRNA or Sp1 siRNA ameliorated the effect of GlcN. When PTCs were transfected with GRP78 siRNA or HIF‐1α siRNA, SGLT expression and α‐MG uptake was decreased. Taken together, these data suggest that GlcN‐induced O‐GlcNAc modified Sp1 with stimulating GRP78 and HIF‐1α activity ameliorate hypoxia‐induced SGLT dysfunction in renal PTCs. J. Cell. Physiol. 229: 1557–1568, 2014. © 2014 Wiley Periodicals, Inc.
Both linked and unlinked mutations can alter the intracellular site of synthesis of exported proteins of Escherichia coli

It previously has been demonstrated that synthesis of the periplasmic maltose-binding protein (MBP) and alkaline phosphatase (AP) of Eschericha coli predominantly occurs on membrane-bound polysomes. In this study, signal sequence alterations that adversely affect export of MBP and AP, resulting in their cytoplasmic accumulation as unprocessed precursors, were investigated to determine whether they have an effect on the intracellular site of synthesis of these proteins. Our findings indicate that export-defective MBP and AP are not synthesized or are synthesized in greatly reduced levels on membrane-bound polysomes. In some instances, a concomitant increase in the amount of these proteins synthesized on free polysomes was clearly discerned. We also determined the site of synthesis of MBP and AP in strains harboring mutations thought to alter the cellular secretion machinery. It was found that the presence of a prlA suppressor allele partially restored synthesis of export-defective MBP on membrane-bound polysomes. On the other hand, the absence of a functional SecA protein resulted in the synthesis of wild-type MBP and AP predominantly on free polysomes.
Dairy Fat Consumption and Mortality due to Cardiovascular Disease. Does Source of Fats Matter

This study analyzed data for correlation between dairy fat availability for consumption and cardiovascular mortality, in adults of both sexes from 35 to 74 years of age, across a selection of countries. In addition we focused on the dietary levels of vegetable and animal fats in countries with high and low cardiovascular mortality.Mortality statistics were taken from the WHO, 2014. Data pertaining to fat availability for consumption was obtained from Food Balance Sheets (FAOStat, 2011). Consumption patterns of animal and vegetal fats were analyzed for countries with high and low cardiovascular mortality.Evolution of dairy fat consumption has changed over time. Cardiovascular mortality showed high rates in countries within the region. Countries with low cardiovascular mortality showed higher levels of vegetable fat consumption, while countries with high mortality rates showed higher levels of animal fat consumption. No particular pattern was observed for dairy fat. This study found no significant correlation between dairy fat consumption and cardiovascular mortality.
The potential costs of accounting for genotypic errors in molecular parentage analyses

Genotypic errors, whether due to mutation or laboratory error, can cause the genotypes of parents and their offspring to appear inconsistent with Mendelian inheritance. As a result, molecular parentage analyses are expected to benefit when allowances are made for the presence of genotypic errors. However, a cost of allowing for genotypic errors might also be expected under some analytical conditions, primarily because parentage analyses that assume nonzero genotypic error rates can neither assign nor exclude parentage with certainty. The goal of this work was therefore to determine whether or not such costs might be important under conditions relevant to parentage analyses, particularly in natural populations. Simulation results indicate that the costs may often outweigh the benefits of accounting for nonzero error rates, except in situations where data are available for many marker loci. Consequently, the most powerful approach to handling genotypic errors in parentage analyses might be to apply likelihood equations with error rates set to values substantially lower than the rates at which genotypic errors occur. When applying molecular parentage analyses to natural populations, we advocate an increased consideration of optimal strategies for handling genotypic errors. Currently available software packages contain procedures that can be used for this purpose.
TGF-β-induced activation of mTOR complex 2 drives epithelial–mesenchymal transition and cell invasion

In cancer progression, carcinoma cells gain invasive behavior through a loss of epithelial characteristics and acquisition of mesenchymal properties, a process that can lead to epithelial–mesenchymal transition (EMT). TGF-β is a potent inducer of EMT, and increased TGF-β signaling in cancer cells is thought to drive cancer-associated EMT. Here, we examine the physiological requirement for mTOR complex 2 (mTORC2) in cells undergoing EMT. TGF-β rapidly induces mTORC2 kinase activity in cells undergoing EMT, and controls epithelial cell progression through EMT. By regulating EMT-associated cytoskeletal changes and gene expression, mTORC2 is required for cell migration and invasion. Furthermore, inactivation of mTORC2 prevents cancer cell dissemination in vivo. Our results suggest that the mTORC2 pathway is an essential downstream branch of TGF-β signaling, and represents a responsive target to inhibit EMT and prevent cancer cell invasion and metastasis.
Real-Time Action Detection in Video Surveillance using Sub-Action Descriptor with Multi-CNN

When we say a person is texting, can you tell the person is walking or sitting? Emphatically, no. In order to solve this incomplete representation problem, this paper presents a sub-action descriptor for detailed action detection. The sub-action descriptor consists of three levels: the posture, the locomotion, and the gesture level. The three levels give three sub-action categories for one action to address the representation problem. The proposed action detection model simultaneously localizes and recognizes the actions of multiple individuals in video surveillance using appearance-based temporal features with multi-CNN. The proposed approach achieved a mean average precision (mAP) of 76.6% at the frame-based and 83.5% at the video-based measurement on the new large-scale ICVL video surveillance dataset that the authors introduce and make available to the community with this paper. Extensive experiments on the benchmark KTH dataset demonstrate that the proposed approach achieved better performance, which in turn boosts the action recognition performance over the state-of-the-art. The action detection model can run at around 25 fps on the ICVL and more than 80 fps on the KTH dataset, which is suitable for real-time surveillance applications.
Hypohyperdontia: Agenesis of three third molars and mandibular centrals associated with midline supernumerary tooth in mandible

Agenesis of teeth in a patient who also presents with a supernumerary tooth is one of the rare numerical anomalies in human dentition. Agenesis of third molars was shown to be associated with other missing permanent teeth. A review of literature on hypodontia including third molar agenesis, hyperdontia and a concomitant presence of these two conditions which is termed as hypohyperdontia is presented along with a case showing agenesis of three third molars, both mandibular central incisors and a midline supernumerary tooth.