Miracle-dz/UniFAR-FTUs huggingface dataset:
Do Size and Value Premia Vary Across Industry and Market Conditions? Evidence from the Euro Area

This paper investigates whether value and size premia exist in the Euro areaâ€™s industry returns and, if so, what factors are driving them. We use a Garch-M (1,1) model on daily return data from the STOXX market indices for five major industries in the euro area. Our findings show that an industry-specific three-factor Fama and French type model does provide a robust explanation of returns over the period, 2001-2012. While, our results further emphasize the widespread influence of the value and size effects in the Euro market, the pattern, sign, size, and significance of these factors vary widely across different industries and market conditions.
Isolation and characterization of embryonic stem‐like cells derived from in vivo‐produced cat blastocysts

Embryonic stem (ES)‐like cells were isolated from in vivo‐produced cat embryos. Total of 101 blastocysts were collected from female cats. The inner cell mass (ICM) were mechanically isolated and cultured on mitomycin‐C‐treated cat embryonic fibroblast feeder layers in medium supplemented with knockout™ Serum Replacement (KSR‐medium) or fetal bovine serum (FBS‐medium). Putative ES‐like cell colonies developed in both KSR‐ and FBS‐medium conditions, but formed domed and flat colonies, respectively. ICM cell attachment and ES‐like cell colony formation were significantly higher in KSR‐medium, but subsequent cell proliferation was significantly lower than in FBS‐medium. For passaging, 32 and 18 colonies in KSR‐ and FBS‐medium were separated by enzymatic dissociation or mechanical disaggregation. Enzymatic dissociation resulted in cell differentiation; however, mechanical disaggregation generated cells that remained undifferentiated over more than four passages and yielded two cat ES‐like cell lines that continued to grow for up to eight passages in FBS‐medium. These cells had typical stem cell morphology, expressed high levels of alkaline phosphatase activity, and were positive for the ES cell‐markers Oct‐4, stage‐specific embryonic antigen‐1 (SSEA‐1), SSEA‐3, and SSEA‐4. These cells formed embryoid bodies (EBs) in suspension culture after extended suspension culture. When simple EBs were cultured on tissue culture plates, they differentiated into several cell types, including epithelium‐like and neuron‐like cells. In addition, EBs were positive for mesoderm marker, desmin. After prolonged in vitro culture, some colonies spontaneously differentiated into beating myocardiocytes, and were positive for alpha‐actinin. These observations indicate that cat ES‐like cells were successfully isolated and characterized from in vivo‐produced blastocysts. Mol. Reprod. Dev. 75: 1426–1432, 2008. © 2008 Wiley‐Liss, Inc.
Making the familiar strange: can visual research methods render the familiar setting more perceptible?

The centrality of the researcher and their position in relation to the research setting has been subject to controversy and long standing debates threaded with the narratives of insider and outsider myths. Insiders are often charged with the tendency to present their group in an unrealistically favourable light, and their work is often considered to be overshadowed by the enclosed, self-contained world of common understanding. This article draws upon data generated by six participants from a research project, which aimed to explore and represent the everyday experiences of working-class mothers and daughters residing on a peripheral social housing estate. The article describes how I, as an indigenous researcher, employed visual methods of data production in order to suspend my preconceptions of familiar territory, and facilitate an understanding of the unique viewpoints of mothers and daughters on the margins of contemporary Britain. The article focuses the usefulness of the approach for making the familiar strange when the researchers own experience mirrors that of their participants.
Recent progress in nanofluids based on transformer oil: preparation and electrical insulation properties

Given the adoption of ultrahigh-voltage ac and dc power transmission, it is desirable to develop a new kind of oil-paper insulation system, with higher dielectric strength and smaller volume compared with conventional insulation systems, in order to reduce the volume and mass of high-voltage power transformers and improve their long-term operational reliability [1], [2]. Methods of improving the dielectric properties of the oil-paper insulation have therefore been widely investigated [3], [4]. The most influential factors affecting the performance of oil-paper insulation systems are the low dielectric strength of transformer oil and its degradation caused by water and other contaminants [5]. The dielectric strength of oil-paper insulation may be increased by filtering the oil in order to remove water and other contaminants [6]. However, further increase in the dielectric strength of the oil is required in order to achieve reduction of transformer volume and mass.
Modification of pain on injection of propofol

One hundred and fifty ASA 1 and 2 patients were randomly allocated to receive pethidine 25 mg (1 ml), lignocaine Wing (1 ml) or 0.9% saline (1 ml) on a double‐blind basis, as pretreatment to reduce pain on injection of propofol. Both active treatments were significantly better than placebo at preventing pain (p<0.01). Lignocaine was most effective in preventing pain in men (p<0.05) whilst pethidine was more effective in women (p<0.05).
Unfair treatment, racial/ethnic discrimination, ethnic identification, and smoking among Asian Americans in the National Latino and Asian American Study.

OBJECTIVES We examined the relations of self-report of general unfair treatment and self-report of race/ethnicity-specific discrimination with current smoking among Asian Americans. We investigated whether ethnic identification moderated either association. METHODS Weighted logistic regressions were performed among 1977 Asian Americans recruited to the National Latino and Asian American Study (2002-2003). RESULTS In weighted multivariate logistic regression models including both general unfair treatment and racial/ethnic discrimination, odds of current smoking were higher among Asian Americans who reported high levels of unfair treatment (odds ratio [OR]=2.80; 95% confidence interval [CI]=1.13, 6.95) and high levels of racial/ethnic discrimination (OR=2.40; 95% CI=0.94, 6.12) compared with those who reported no unfair treatment and discrimination, respectively. High levels of ethnic identification moderated racial/ethnic discrimination (F(3) =3.25; P =. 03). High levels of ethnic identification were associated with lower probability of current smoking among participants reporting high levels of racial/ethnic discrimination. CONCLUSIONS Our findings suggest that experiences of unfair treatment and racial/ethnic discrimination are risk factors for smoking among Asian Americans. Efforts to promote ethnic identification may be effective in mitigating the influence of racial/ethnic discrimination on smoking in this population.
Assessment of Functional Capacity in Chagas Heart Disease by Incremental Shuttle Walk Test and its Relation to Quality-of-Life

Background: The cardiopulmonary exercise test (CPET) is considered to be the gold standard to evaluate functional capacity (FC) in patients with heart failure. However, field tests such as the 6-min walk test (6MWT) and the incremental shuttle walk test (ISWT) are simple and effective in evaluating the same. Despite the increasing use of ISWT, no studies that used the test in patients with Chagas heart disease (CHD) were found and only few studies have evaluated the health-related quality-of-life (HRQoL) in this population. The objective of this study was to correlate the distance walked in the ISWT with distance walked by 6MWT and peak oxygen uptake (VO2peak) by CPET and HRQoL in patients with CHD. Methods: A total of 35 patients with CHD were evaluated according to the FC and HRQoL. The FC was assessed by CPET, 6MWT and ISWT. HRQoL was assessed by the generic short-form health survey (SF-36) and Minnesota Living with Heart Failure Questionnaire (MLHFQ). Descriptive data were shown as mean and standard deviation or median and interquartile range. The correlation was carried out with Pearson or Spearman correlation test. A receiver operating characteristic (ROC) curve was constructed to investigate the accuracy of ISWT for predicting low values of VO2peak. Results: The distance walked in ISWT correlated with VO2peak(r = 0.587; P < 0.001), distance walked in 6MWT (r = 0.484; P = 0.003), MLWHFQ scores (r = −0.460; P = 0.006) and physical functioning and role physical domains of the SF-36 scores (r = 0.435, P = 0.009; r = 0.477, P = 0.008, respectively). There was no significant difference between the distances walked in field tests (P = 0.694). The area under the ROC curve was 0.871 for ISWT in predicts a VO2peak value of, at least, 25 mL/kg/min. Conclusions: The ISWT showed to be effective in evaluating the FC in CHD and in demonstrate the impact of disease on some aspects of the HRQoL of these patients.
From Gaussian to Paretian Thinking: Causes and Implications of Power Laws in Organizations

A lthough normal distributions and related current quantitative methods are still relevant for some organizational research, the growing ubiquity of power laws signiﬁes that Pareto rank/frequency distributions, fractals, and underlying scale-free theories are increasingly pervasive and valid characterizations of organizational dynamics. When they apply, researchers ignoring power-law effects risk drawing false conclusions and promulgating useless advice to practitioners. This is because what is important to most managers are the extremes they face, not the averages. We show that power laws are pervasive in the organizational world and present 15 scale-free theories that apply to organizations. Next we discuss research implications embedded in Pareto rank/frequency distributions and draw statistical and methodological implications.
Utility of glucose transporter 1 in the distinction of benign and malignant thoracic and abdominal mesothelial lesions.

CONTEXT Malignant mesothelioma, of either peritoneum or pleura, is an uncommon cancer. The diagnosis is often difficult to make, in part because of the overlapping morphology of reactive and malignant mesothelial cells. Glucose transporter 1 (GLUT-1) is a glucose transporter typically found on erythrocytes, which is aberrantly expressed in various carcinomas. It has recently been reported as specific and sensitive in discriminating malignant pleural mesothelioma from reactive hyperplasia. The application of GLUT-1 staining in peritoneal mesothelioma has not been fully explored. OBJECTIVE To determine if GLUT-1 staining is helpful in distinguishing abdominal mesotheliomas from benign, reactive mesothelial lesions and to further study its utility in the thorax. DESIGN Tissue microarrays containing 135 abdominal malignant mesotheliomas and 30 malignant pleural mesotheliomas were stained with an antibody to GLUT-1, as were 56 reactive mesothelial lesions. RESULTS The overall sensitivity and specificity for GLUT-1 in mesothelioma was 53% and 98%, respectively. The sensitivity in epithelioid malignant mesothelioma was 49% and in sarcomatoid/biphasic malignant mesothelioma, 66%. In the thorax, the sensitivity was 50% and in the abdomen it was 54%. The positive predictive value of GLUT-1 immunoreactivity was 98% and the negative predictive value was 40%. CONCLUSION Glucose transporter 1 staining of thoracic mesotheliomas showed high specificity but lower sensitivity than previously reported. Abdominal malignant mesotheliomas showed similar results. Because of low sensitivity, only positive staining is informative. In both sites, the utility of the stain was limited by nonspecific staining (eg, in necrotic areas) as well as bright labeling of erythrocytes and occasional lymphoid elements. Despite these limitations, GLUT-1 can help differentiate malignant mesothelioma from reactive benign mesothelium.
Sickness absence and ventilatory capacity of workers exposed to sulphuric acid mist

Williams, M. K. (1970). Brit. J. industr. Med.,27, 61-66. Sickness absence and ventilatory capacity of workers exposed to sulphuric acid mist. The certified sickness absence and ventilatory capacity of men exposed to high concentrations of sulphuric acid mist in the Forming department of an electric accumulator factory, and in control departments, were investigated. The Forming men showed a slight excess of spells of respiratory disease, particularly bronchitis, but not of other disease. The excess of repiratory disease was due to an increased number of spells in men attacked rather than to an increase in the proportion of men attacked. The absence of a marked excess of lower respiratory tract disease might be due to large mist particle size. The forced expiratory volume over one second (F.E.V.1·0) and the forced vital capacity (F.V.C.) were measured in Forming men and in a control group at the beginning and end of the afternoon shifts on a Monday and Friday. Statistically significant decreases of both tests on both days could be attributed to circadian variation. Differences between the Forming and control departments in the mean changes of F.E. V.1·0 and F.V. C. during the shift were not significant.
Collapse, outflows and fragmentation of massive, turbulent and magnetized prestellar barotropic cores

Context. Stars, and more particularly massive stars, have a drastic impact on galaxy evolution. Yet the conditions in which they form and collapse are still not fully understood. Aims: In particular, the influence of the magnetic field on the collapse of massive clumps is relatively unexplored, it is therefore of great relevance in the context of the formation of massive stars to investigate its impact. Methods: We perform high resolution, MHD simulations of the collapse of one hundred solar masses, turbulent and magnetized clouds, with the adaptive mesh refinement code RAMSES. We compute various quantities such as mass distribution, magnetic field, and angular momentum within the collapsing core and study the episodic outflows and the fragmentation that occurs during the collapse. Results: The magnetic field has a drastic impact on the cloud evolution. We find that magnetic braking is able to substantially reduce the angular momentum in the inner part of the collapsing cloud. Fast and episodic outflows are being launched with typical velocities of the order of 1-3 km s-1, although the highest velocities can be as high as 20-40 km s-1. The fragmentation in several objects is reduced in substantially magnetized clouds with respect to hydrodynamical ones by a factor of the order of 1.5-2. Conclusions: We conclude that magnetic fields have a significant impact on the evolution of massive clumps. In combination with radiation, magnetic fields largely determine the outcome of massive core collapse. We stress that numerical convergence of MHD collapse is a challenging issue. In particular, numerical diffusion appears to be important at high density and therefore could possibly lead to an overestimation of the number of fragments.
Poor stimulus discriminability as a common neuropsychological deficit between ADHD and reading ability in young children: a moderated mediation model

Background Attention deficit hyperactivity disorder (ADHD) is frequently associated with poorer reading ability; however, the specific neuropsychological domains linking this co-occurrence remain unclear. This study evaluates information-processing characteristics as possible neuropsychological links between ADHD symptoms and RA in a community-based sample of children and early adolescents with normal IQ (⩾70). Method The participants (n = 1857, aged 6–15 years, 47% female) were evaluated for reading ability (reading single words aloud) and information processing [stimulus discriminability in the two-choice reaction-time task estimated using diffusion models]. ADHD symptoms were ascertained through informant (parent) report using the Development and Well-Being Assessment (DAWBA). Verbal working memory (VWM; digit span backwards), visuospatial working memory (VSWM, Corsi Blocks backwards), sex, socioeconomic status, and IQ were included as covariates. Results In a moderated mediation model, stimulus discriminability mediated the effect of ADHD on reading ability. This indirect effect was moderated by age such that a larger effect was seen among younger children. Conclusion The findings support the hypothesis that ADHD and reading ability are linked among young children via a neuropsychological deficit related to stimulus discriminability. Early interventions targeting stimulus discriminability might improve symptoms of inattention/hyperactivity and reading ability.
Changes in Adult Attachment Styles in American College Students Over Time

The current article examines changes over time in a commonly used measure of adult attachment style. A cross-temporal meta-analysis was conducted on 94 samples of American college students (total N = 25,243, between 1988 and 2011) who chose the most representative description of four possible attachment styles (Secure, Dismissing, Preoccupied, and Fearful) on the Relationship Questionnaire. The percentage of students with Secure attachment styles has decreased in recent years (1988: 48.98%; 2011: 41.62%), whereas the percentage of students with Insecure attachment styles (sum of Dismissing, Preoccupied, Fearful) has increased in recent years (1988: 51.02%; 2011: 58.38%). The percentage of students with Dismissing attachment styles has increased over time (1988: 11.93%; 2011: 18.62%), even after controlling for age, gender, race, and publication status. Positive views of others have declined across the same time period. We discuss possible implications and explanations for these changes.
Methodology and Demographics of a Brief Adolescent Alcohol Screen Validation Study.

OBJECTIVE The aim of this study was to determine the psychometric properties of the National Institute on Alcohol Abuse and Alcoholism (NIAAA) 2-question alcohol screen within 16 Pediatric Emergency Care Applied Research Network pediatric emergency departments. This article describes the study methodology, sample characteristics, and baseline outcomes of the NIAAA 2-question screen. METHODS Participants included 12- to 17-year-olds treated in one of the participating pediatric emergency departments across the United States. After enrollment, a criterion assessment battery including the NIAAA 2-question screen and other measures of alcohol, drug use, and risk behavior was self-administered by participants on a tablet computer. Two subsamples were derived from the sample. The first subsample was readministered the NIAAA 2-question screen 1 week after their initial visit to assess test-retest reliability. The second subsample is being reassessed at 12 and 24 months to examine predictive validity of the NIAAA 2-question screen. RESULTS There were 4834 participants enrolled into the study who completed baseline assessments. Participants were equally distributed across sex and age. Forty-six percent of the participants identified as white, and 26% identified as black. Approximately one quarter identified as Hispanic. Using the NIAAA 2-question screen algorithm, approximately 8% were classified as low risk, 12% were classified as moderate risk, and 4% were classified as highest risk. Alcohol use was less likely to be reported by black participants, non-Hispanic participants, and those younger than 16 years. DISCUSSION This study successfully recruited a large, demographically diverse sample to establish rates of the NIAAA screen risk categories across age, sex, ethnicity, and race within pediatric emergency departments.
The Xenopus laevis poly(A) binding protein is composed of multiple functionally independent RNA binding domains.

A family of eukaryotic RNA binding proteins is defined by the conserved RNP motif. The poly(A) binding protein has four such motifs. We report on the isolation and structural characterization of several variant cDNA clones, as well as of a gene encoding this protein in Xenopus laevis embryos. Wild‐type protein as well as truncated versions carrying isolated single motifs or artificial combinations of two and more such elements were characterized for their ability to bind specifically to RNA homopolymers. Three of the isolated repeats were functional in specific RNA binding, whereas the N‐terminal RNP motif was non‐functional. Combinatorial effects in RNA binding were measured with constructs carrying multiple repeats, which were not predictable from the activity of isolated domains.
Clinical Proteomics: A Novel Diagnostic Tool for the New Biology of Preterm Labor, Part I: Proteomics Tools

The molecular mechanisms regulating myometrial contractility and preterm premature rupture of the membranes leading to preterm birth are poorly understood. The completion of the human genome sequence led to the development of functional genomics and gene array technology to simultaneously identify candidate genes potentially involved in regulation of human parturition. However, the study of living systems can now be expanded past genomics based on the rationale that it is the protein products of the genes, not simply gene expression, that have effects and cause disturbances at the cellular level. Therefore, identification of disease biomarkers, followed by a description of their functional networks, has the potential to significantly aid the development of new strategies for the prediction, diagnosis, and prevention of preterm birth. Interest in mass spectrometry and its use as a new clinical diagnostic tool has grown rapidly and is poised to become an important medical field for the next century. Target Audience: Obstetricians & Gynecologists, Family Physicians Learning Objectives: After completion of this article, the reader should be able to state the general concept of proteomics, summarize the use of proteomics as a potential clinical tool as a biomarker of disease, and recall that proteomics can be a means for understanding mechanisms of disease states.
Anatomical study of the connections of the primary auditory area in the rat

The aim of the present study was to identify in the rat the overall input‐output pattern of connections of the primary auditory field, with special attention to the topographical organization of the geniculocortical auditory projection. By using cytoarchitectural criteria, three temporal cortical fields were distinguished in the rat: Te1, Te2, and Te3. The primary auditory field Te1 is characterized by a relatively specific differentiation of its layers when compared with other temporal fields. The afferent and efferent connections of Te1 were identified by using the retrograde and anterograde transport of wheat germ agglutinin conjugated with horseradish peroxidase (WGA‐HRP).