Miracle-dz/UniFAR-FTUs huggingface dataset:
Containers and Virtual Machines at Scale: A Comparative Study

Virtualization is used in data center and cloud environments to decouple applications from the hardware they run on. Hardware virtualization and operating system level virtualization are two prominent technologies that enable this. Containers, which use OS virtualization, have recently surged in interest and deployment. In this paper, we study the differences between the two virtualization technologies. We compare containers and virtual machines in large data center environments along the dimensions of performance, manageability and software development. We evaluate the performance differences caused by the different virtualization technologies in data center environments where multiple applications are running on the same servers (multi-tenancy). Our results show that co-located applications can cause performance interference, and the degree of interference is higher in the case of containers for certain types of workloads. We also evaluate differences in the management frameworks which control deployment and orchestration of containers and VMs. We show how the different capabilities exposed by the two virtualization technologies can affect the management and development of applications. Lastly, we evaluate novel approaches which combine hardware and OS virtualization.
Keys to Bowel Success

Although many rehabilitation clients have neurogenic bowels requiring special bowel protocols, a review of the literature affirmed the authors' assumptions and experiences as professional nurses that any bowel program must begin with a good nursing assessment, a clean bowel, and eight keys to success. Once these criteria are met, bowel care can be individualized to meet the needs of the specific patient. This article presents a review of the literature and provides references for nurses seeking additional information on bowel programs.
Tamoxifen alters the plasma concentration of molecules associated with cardiovascular risk in women with breast cancer undergoing chemotherapy.

OBJECTIVES The objective of this study was to evaluate the effect of tamoxifen on blood markers that are associated with cardiovascular risk, such as C-reactive protein (CRP), apolipoprotein A-1 (Apo-A), and apolipoprotein B-100 (Apo-B), in women undergoing chemotherapy for breast cancer. METHODS Over a period of 12 months, we followed 60 women with breast cancer. The women were divided into the following groups: a group that received only chemotherapy (n = 23), a group that received chemotherapy plus tamoxifen (n = 21), and a group that received only tamoxifen (n = 16). Plasma CRP levels were assessed at 0, 3, 6, and 12 months, and Apo-A and Apo B levels as well as the Apo-B/Apo-A ratio were assessed at 0 and 12 months. RESULTS We found increases in the plasma concentration of CRP in the chemotherapy alone and chemotherapy plus tamoxifen groups after 3 and 6 months of treatment (before the introduction of tamoxifen). However, after 12 months of treatment, women who used tamoxifen (the chemotherapy plus tamoxifen and tamoxifen alone groups) showed a significant reduction in CRP and Apo-B levels and a decrease in the Apo-B/Apo-A ratio. A significant increase in serum Apo-A levels was observed in the group receiving chemotherapy alone as a treatment for breast cancer. CONCLUSION The use of tamoxifen after chemotherapy for the treatment of breast cancer significantly reduces the levels of cardiovascular disease risk markers (CRP, Apo-B, and the Apo-B/Apo-A ratio).
Quasi-Newton Methods for Real-Time Simulation of Hyperelastic Materials

We present a new method for real-time physics-based simulation supporting many different types of hyperelastic materials. Previous methods such as Position-Based or Projective Dynamics are fast but support only a limited selection of materials; even classical materials such as the Neo-Hookean elasticity are not supported. Recently, Xu et al. [2015] introduced new “spline-based materials” that can be easily controlled by artists to achieve desired animation effects. Simulation of these types of materials currently relies on Newton’s method, which is slow, even with only one iteration per timestep. In this article, we show that Projective Dynamics can be interpreted as a quasi-Newton method. This insight enables very efficient simulation of a large class of hyperelastic materials, including the Neo-Hookean, spline-based materials, and others. The quasi-Newton interpretation also allows us to leverage ideas from numerical optimization. In particular, we show that our solver can be further accelerated using L-BFGS updates (Limited-memory Broyden-Fletcher-Goldfarb-Shanno algorithm). Our final method is typically more than 10 times faster than one iteration of Newton’s method without compromising quality. In fact, our result is often more accurate than the result obtained with one iteration of Newton’s method. Our method is also easier to implement, implying reduced software development costs.
EvilCoder: automated bug insertion

The art of finding software vulnerabilities has been covered extensively in the literature and there is a huge body of work on this topic. In contrast, the intentional insertion of exploitable, security-critical bugs has received little (public) attention yet. Wanting more bugs seems to be counterproductive at first sight, but the comprehensive evaluation of bug-finding techniques suffers from a lack of ground truth and the scarcity of bugs. In this paper, we propose EvilCoder, a system to automatically find potentially vulnerable source code locations and modify the source code to be actually vulnerable. More specifically, we leverage automated program analysis techniques to find sensitive sinks which match typical bug patterns (e.g., a sensitive API function with a preceding sanity check), and try to find data-flow connections to user-controlled sources. We then transform the source code such that exploitation becomes possible, for example by removing or modifying input sanitization or other types of security checks. Our tool is designed to randomly pick vulnerable locations and possible modifications, such that it can generate numerous different vulnerabilities on the same software corpus. We evaluated our tool on several open-source projects such as for example libpng and vsftpd, where we found between 22 and 158 unique connected source-sink pairs per project. This translates to hundreds of potentially vulnerable data-flow paths and hundreds of bugs we can insert. We hope to support future bug-finding techniques by supplying freshly generated, bug-ridden test corpora so that such techniques can (finally) be evaluated and compared in a comprehensive and statistically meaningful way.
The Achilles heel of OAuth: a multi-platform study of OAuth-based authentication

Websites and mobile applications today increasingly utilize OAuth for authorization and authentication. Major companies such as Facebook, Google and Twitter all provide OAuth services. The usage of OAuth for authorization is well documented and has been studied by many researchers. However, little work has been done to specify or analyze the usage of OAuth for authentication. Given that many developers have employed OAuth for authentication on multiple platforms, we believe it is imperative to conduct a study to understand how developers customize OAuth for authentication on different platforms. In this paper, we analyze how popular applications on the Web, Android and iOS platform authenticate users with OAuth. Our approach is to dissect the traffic from an attacker's perspective to recover the authentication mechanisms employed by the apps and identify exploitable vulnerabilities. The results show that OAuth-based authentication mechanisms employed by these applications lack sufficient verification and suffer from many vulnerabilities. Closer examination reveals that developers have different tendencies to authenticate users with OAuth on different platforms, and 32.9%, 47.1% and 41.6% of the analyzed mechanisms on the three platforms are vulnerable. We then categorize the root causes of these vulnerabilities and make practical recommendations for developers to help design and implement robust authentication mechanisms with OAuth.
Agreement in risk prediction between the 21-gene recurrence score assay (Oncotype DX®) and the PAM50 breast cancer intrinsic Classifier™ in early-stage estrogen receptor-positive breast cancer.

PURPOSE To compare risk assignment by PAM50 Breast Cancer Intrinsic Classifier™ and Oncotype DX_Recurrence Score (RS) in the same population. METHODS RNA was extracted from 151 estrogen receptor (ER)+ stage I-II breast cancers and gene expression profiled using PAM50 "intrinsic" subtyping test. RESULTS One hundred eight cases had complete molecular information; 103 (95%) were classified as luminal A (n = 76) or luminal B (n = 27). Ninety-two percent (n = 98) had a low (n = 59) or intermediate (n = 39) RS. Among luminal A cancers, 70% had low (n = 53) and the remainder (n = 23) had an intermediate RS. Among luminal B cancers, nine were high (33%) and 13 were intermediate (48%) by the RS. Almost all cancers with a high RS were classified as luminal B (90%, n = 9). One high RS cancer was identified as basal-like and had low ER/ESR1 and low human epidermal growth factor receptor 2 (HER2) expression by quantitative polymerase chain reaction in both assays. The majority of low RS cases were luminal A (83%, n = 53). Importantly, half of the intermediate RS cancers were re-categorized as low risk luminal A subtype by PAM50. CONCLUSION There is good agreement between the two assays for high (i.e., luminal B or RS > 31) and low (i.e., luminal B or RS < 18) prognostic risk assignment but PAM50 assigns more patients to the low risk category. About half of the intermediate RS group was reclassified as luminal A by PAM50.
Building consumer trust online

M oving some Web consumers along to the purchase click is proving to be difficult, despite the impressive recent growth in online shopping. Consumer online shopping revenues and related corporate profits are still meager, though the industry is optimistic, thanks to bullish forecasts of cyberconsumer activity for the new millennium. In 1996, Internet shopping revenues for U.S. users, excluding cars and real estate, were estimated by Jupiter Communications , an e-commerce consulting firm in New York, at approximately $707 million but are expected to How merchants can win back lost consumer trust in the interests of e-commerce sales. reach nearly $37.5 billion by 2002 [1]. Meanwhile, the business-to-business side is taking off with more than $8 billion in revenues for 1997 and $327 billion predicted by 2002 just in the U.S., according to For-rester Research, an information consulting firm in Cambridge, Mass. [4]. On the consumer side, a variety of barriers are invoked to explain the continuing difficulties. There are, to be sure, numerous barriers. Such factors as the lack of standard technologies for secure payment, and the lack of profitable business models play important roles in the relative dearth of commercial activity by businesses and consumers on the Internet compared to what analysts expect in the near future. Granted, the commercial development of the Web is still in its infancy, so few expect these barriers to commercial development to persist. Still, commercial development of the Web faces a far more formidable barrier—consumers' fear of divulging their personal data—to its ultimate com-mercialization. The reason more people have yet to shop online or even provide information to Web providers in exchange for access to information, is the fundamental lack of faith between most businesses and consumers on the Web today. In essence, consumers simply do not trust most Web providers enough to engage in " relationship exchanges " involving money and personal information with them. Our research reveals that this lack of trust arises from the fact that cyberconsumers feel they lack control over the access that Web merchants have to their
Attention as the Mediator Between Top Management Team Characteristics and Strategic Change: The Case of Airline Deregulation

We integrate the upper-echelons perspective with the attention-based view of the firm by examining the role of attentional orientation of top management teams (TMTs). In the context of airline deregulation, we find that deregulation caused a shift in managerial attention, but that this shift in attention was the greatest for firms that changed the composition and compensation of their TMTs in ways that favored the deregulated regime. We also find that attention partially mediated the relationship between TMT changes and strategy changes. The results of this study shed light on the transformation of industry attention patterns following an environmental shift, and the role of TMT composition and incentive systems in that process.
EmotiW 2016: video and group-level emotion recognition challenges

This paper discusses the baseline for the Emotion Recognition in the Wild (EmotiW) 2016 challenge. Continuing on the theme of automatic affect recognition `in the wild', the EmotiW challenge 2016 consists of two sub-challenges: an audio-video based emotion and a new group-based emotion recognition sub-challenges. The audio-video based sub-challenge is based on the Acted Facial Expressions in the Wild (AFEW) database. The group-based emotion recognition sub-challenge is based on the Happy People Images (HAPPEI) database. We describe the data, baseline method, challenge protocols and the challenge results. A total of 22 and 7 teams participated in the audio-video based emotion and group-based emotion sub-challenges, respectively.
Treatment patterns and clinical outcomes in patients with metastatic colorectal cancer initially treated with FOLFOX-bevacizumab or FOLFIRI-bevacizumab: results from ARIES, a bevacizumab observational cohort study.

BACKGROUND The Avastin Registry: Investigation of Effectiveness and Safety (ARIES) study is a prospective, community-based observational cohort study that evaluated the effectiveness and safety of first-line treatment patterns, assessing the impact of chemotherapy choice and treatment duration. METHODS The ARIES study enrolled patients with metastatic colorectal cancer (mCRC) receiving first-line chemotherapy with bevacizumab and followed them longitudinally. The protocol did not specify treatment regimens or assessments. Analyses included all patients who initiated bevacizumab in combination with either first-line oxaliplatin with infusional 5-fluorouracil and leucovorin (FOLFOX) or irinotecan with infusional 5-fluorouracil and leucovorin (FOLFIRI). Progression-free survival (PFS) and overall survival (OS) times were estimated using Kaplan-Meier methods. Hazard ratios (HRs) were estimated with multivariate Cox regression analysis, adjusting for potential confounding factors. RESULTS In total, 1,550 patients with first-line mCRC were enrolled (median follow-up, 21 months) and most received FOLFOX-bevacizumab (n = 968) or FOLFIRI-bevacizumab (n = 243) as first-line therapy. The baseline characteristics and median treatment duration were generally similar between subgroups. There were no significant differences in the median PFS (10.3 months vs. 10.2 months) or OS (23.7 months vs. 25.5 months) time between the FOLFOX-bevacizumab and FOLFIRI-bevacizumab subgroups, respectively, by unadjusted analyses. Multivariate analyses showed FOLFIRI-bevacizumab resulted in a similar PFS (HR, 1.03; 95% confidence interval [CI], 0.88-1.21) and OS (HR, 0.95; 95% CI, 0.78-1.16) outcome as with FOLFOX-bevacizumab. The incidence proportions of bevacizumab-associated adverse events were similar for FOLFOX- and FOLFIRI-based therapies. CONCLUSIONS In first-line mCRC patients, the FOLFOX-bevacizumab and FOLFIRI-bevacizumab regimens were associated with similar treatment patterns and clinical outcomes.
Perspective - Neo-Carnegie: The Carnegie School's Past, Present, and Reconstructing for the Future

Cyert and March's (1963) A Behavioral Theory of the Firm and the broader Carnegie School form critical theoretical underpinnings for modern organization studies. Despite its impact, however, we suggest that researchers who rely on the Carnegie School have progressively lost touch with its defining commitment to a decision-centered view of organizations. Decision making has given way to learning, routines, and an increased focus on change and adaptation; the organizational level of analysis, although frequently invoked, has been largely supplanted by either a more micro or a more macro focus. In this paper, we argue for restoring the School's original mission and perspective. Our proposal for how this overarching goal can be achieved encompasses three central points. First, we believe the School needs to resurrect a few select ideas that, despite their fundamental importance, have been neglected over time. Second, we believe there is a need for greater paradigmatic closure amongst the School's central theoretical pillars. Loose coupling among such pillars might keep key insights on organizational decision making from emerging. Finally, there is the need to incorporate major developments that have been generated post-Carnegie School, both within organization theory and in the behavioral and social sciences more broadly. In particular, we point to the shift to more open systems perspectives on organizations, the conceptions of organizations being embedded in larger social contexts, and recent developments in the study of individual cognition.
Brick: Towards a Unified Metadata Schema For Buildings

Commercial buildings have long since been a primary target for applications from a number of areas: from cyber-physical systems to building energy use to improved human interactions in built environments. While technological advances have been made in these areas, such solutions rarely experience widespread adoption due to the lack of a common descriptive schema which would reduce the now-prohibitive cost of porting these applications and systems to different buildings. Recent attempts have sought to address this issue through data standards and metadata schemes, but fail to capture the set of relationships and entities required by real applications. Building upon these works, this paper describes Brick, a uniform schema for representing metadata in buildings. Our schema defines a concrete ontology for sensors, subsystems and relationships among them, which enables portable applications. We demonstrate the completeness and effectiveness of Brick by using it to represent the entire vendor-specific sensor metadata of six diverse buildings across different campuses, comprising 17,700 data points, and running eight complex unmodified applications on these buildings.
Measuring Cognitive Load using Eye Tracking Technology in Visual Computing

In this position paper we encourage the use of eye tracking measurements to investigate users' cognitive load while interacting with a system. We start with an overview of how eye movements can be interpreted to provide insight about cognitive processes and present a descriptive model representing the relations of eye movements and cognitive load. Then, we discuss how specific characteristics of human-computer interaction (HCI) interfere with the model and impede the application of eye tracking data to measure cognitive load in visual computing. As a result, we present a refined model, embedding the characteristics of HCI into the relation of eye tracking data and cognitive load. Based on this, we argue that eye tracking should be considered as a valuable instrument to analyze cognitive processes in visual computing and suggest future research directions to tackle outstanding issues.
Successful treatment of polyomavirus infection in kidney allograft recipients: case reports and literature review

Background: Polyomavirus nephropathy, also termed BK virus nephropathy, is an infectious complication after kidney transplantation, causing allograft failure. The state of immunosuppression of the patient is the principal risk for the infection. Most cases of BK virus nephropathy were associated with the use of potent immunosuppressive regimens like tacrolimus and mycophenolate mofetil. To the best of our knowledge, no patient with BK virus nephropathy has been reported in Southeast Asia. Objective: We report two cases of BK virus nephropathy in patients who received the immunosuppressive regimen of sirolimus with cyclosporine. We also review the literature regarding the pathogenesis, clinical manifestations, and treatment strategies.
Imaging of bladder cancer

Bladder cancer is the fourth most common cancer in males and the eleventh most common cancer in females in the UK.Bladder cancer is more common in males than in females.The majority of primary bladder tumours are epithelial in origin: 95% of these are urothelial tumours (or transitional cell carcinomas). Cigarette smoking and occupation are the greatest risk factors for developing bladder cancer.Multifocal tumours (bladder and/or upper tract) are seen in 30–40% of patients.The role of imaging in patients with bladder cancer is to assess the local extent of disease and to detect nodal and distant metastases once a malignant diagnosis is established. Bladder cancer is a relatively common cancer and, while imaging is rarely required to make the diagnosis, it plays an important role in the staging and follow-up of patients with this malignancy. This review discusses the indications and limitations of currently available imaging modalities.
Mobile IP Handover for Vehicular Networks

The popularity and development of wireless devices has led to a demand for widespread high-speed Internet access, including access for vehicles and other modes of high-speed transportation. The current widely deployed method for providing Internet Protocol (IP) services to mobile devices is the mobile IP. This includes a handover process for a mobile device to maintain its IP session while it switches between points of access. However, the mobile IP handover causes performance degradation due to its disruptive latency and high packet drop rate. This is largely problematic for vehicles, as they will be forced to transition between access points more frequently due to their higher speeds and frequent topological changes in vehicular networks. In this article, we discuss the different mobile IP handover solutions found within related literature and their potential for resolving issues pertinent to vehicular networks. First, we provide an overview of the mobile IP handover and its problematic components. This is followed by categorization and comparison between different mobile IP handover solutions, with an analysis of their benefits and drawbacks.
Annotation: Paediatric HIV Infection

HIV and AIDS have made a huge global impact, permeating the social, cultural, and economic fabric of almost all nations. The first cases of HIV infection in children were reported in the late 1980s and numbers have since risen steadily throughout the world, with some of the poorest and least developed countries experiencing the highest prevalence. Combined drug regimes have changed the course of HIV-related illness and brought increased survival to those for whom treatment is available. With this, however, have come fresh concerns relating to drug resistance, treatment adherence, and the risk of second-generation vertical transmission as HIV-infected children now survive into adulthood and beyond. The psychological literature has addressed issues such as the direct effect of HIV on child development, social and cultural attitudes, family functioning and support, affected children and orphans of HIV-infected parents, sexual health education, disclosure of diagnosis, and long-term clinical management. The outcome for those living in wealthier countries is optimistic, but the spread of this virus in the rest of the world and its impact on family life and social and political systems remains of great concern.