Miracle-dz/UniFAR-FTUs huggingface dataset:
Arthroscopic Labral Repair and Treatment of Femoroacetabular Impingement in Professional Hockey Players

Background Hip injuries are common among professional hockey players in the National Hockey League (NHL). Hypothesis Professional hockey players will return to a high level of function and ice hockey after arthroscopic labral repair and treatment of femoroacetabular impingement. Study Design Case series; Level of evidence, 4. Methods Twenty-eight professional hockey players (NHL) were unable to perform at the professional level due to unremitting and debilitating hip pain. Players underwent arthroscopic labral repair and were treated for femoroacetabular impingement from March 2005 to December 2007. Players who had bilateral hip symptoms were excluded. Athletes completed the Modified Harris Hip Score preoperatively and postoperatively and also completed a patient satisfaction questionnaire postoperatively. Return to sport was defined as the player resuming skating for training or participation in the sport of ice hockey. Results The average age at the time of surgery was 27 years (range, 18-37). There were 11 left hips and 17 right hips. Player positions included 9 defensemen, 12 offensive players, and 7 goaltenders. All players had labral lesions that required repair. In addition, all patients had evidence of femoroacetabular impingement at the time of surgery. The average time to return to skating/hockey drills was 3.4 months. The average time to follow-up was 24 months (range, 12-42). The Modified Harris Hip Score improved from 70 (range, 57-100) preoperatively to an average of 95 (range, 74-100) at follow-up. The median patient satisfaction was 10 (range, 5-10). Two players had reinjury and required additional hip arthroscopy. Conclusion Treatment of femoroacetabular impingement and labral lesions in professional hockey players resulted in successful outcomes, with high patient satisfaction and prompt return to sport.
Requirements Engineering Visualization: A Systematic Literature Review

Requirements Engineering (RE) is a decision-centric activity which is highly data-intensive. The results of this process are known to have key impact on the results of the project. As known from the experience in other fields and disciplines, visualization can potentially provide more insights into data, information and knowledge studied. While research in the area of information visualization and its application to software engineering has rapidly increased over the last decade, there is only a limited amount of studies addressing the usage and impact of visualization techniques for RE activities. In this paper, we report on the results of a Systematic Literature Review (SLR) related to RE visualization. Extending the established SLR process by the usage of grounded theory for the encoding of papers, we synthesize 18 usage patterns. Even though there are punctual applications, there is a clear deficit on a holistic perspective across the different RE activities. As another conclusion, we derive the clear need for more research on visualization support in particular for tackling requirements uncertainty, requirements verification, and modeling, as well as non-functional requirements (NFRs).
Long-Term Durability of Autologous Chondrocyte Implantation

Background Autologous chondrocyte implantation for full-thickness lesions of the distal femur has demonstrated good short- to midterm clinical improvement. However, long-term durability (>5 years) of autologous chondrocyte implantation has not been evaluated in US patients to date. Hypothesis Patients who improve from baseline to early follow-up will sustain improvement at later follow-up. Study Design Case series, Level of evidence, 4. Methods Cartilage Repair Registry patients with full-thickness distal femur lesions who were treated with autologous chondrocyte implantation before December 31, 1996 and had modified overall Cincinnati scores at baseline and 1- to 5-year follow-up scores were re-evaluated at 6- to 10-year follow-up. Autologous chondrocyte implantation durability was determined by comparing early (1-5 years) to long-term (6-10 years) outcomes. Adverse events and treatment failures were recorded. Results Seventy-two patients met eligibility criteria (at baseline: mean age, 37 years; mean lesion size, 5.2 cm2; and overall condition score, 3.4 points [poor]). Eighty-seven percent of patients (47 of 54) who improved at the earlier follow-up period sustained a mean improvement in overall condition score of 3.8 points from baseline to the later follow-up period (P < .001). From baseline to 10-year follow-up (mean follow-up, 9.2 years), 69% improved, 17% failed, and 12.5% reported no change from baseline. Most failures (75% [9 of 12]) occurred at a mean follow-up of 2.5 years. Thirty patients (42%) had 42 operations after autologous chondrocyte implantation; 24 operations (57%) occurred in patients who met the study definition of failure. Conclusion Treatment with autologous chondrocyte implantation for large, symptomatic, full-thickness lesions of the distal femur can result in early improvement that is sustained at longer follow-up (up to 10 years) in the majority of patients.
Conversion of Sugars to Lactic Acid Derivatives Using Heterogeneous Zeotype Catalysts

Approaching Lactate Inorganically Conversion of biomass to value-added chemical compounds currently relies in large part on fermentation. For full-scale displacement of petroleum as the chemical industry's primary feedstock, alternative conversion technologies will be necessary. Holm et al. (p. 602) have found that Lewis acidic zeolite derivatives suspended in methanol can catalyze the selective conversion of glucose, fructose, and sucrose sugars to methyl lactate, a versatile synthetic intermediate for commercial products. The catalysts were easily separated from product mixtures and proved robust over six reaction and regeneration cycles. Lewis acid catalysis offers an alternative to fermentation in converting sugars to a commercial chemical feedstock. Presently, very few compounds of commercial interest are directly accessible from carbohydrates by using nonfermentive approaches. We describe here a catalytic process for the direct formation of methyl lactate from common sugars. Lewis acidic zeotypes, such as Sn-Beta, catalyze the conversion of mono- and disaccharides that are dissolved in methanol to methyl lactate at 160°C. With sucrose as the substrate, methyl lactate yield reaches 68%, and the heterogeneous catalyst can be easily recovered by filtration and reused multiple times after calcination without any substantial change in the product selectivity.
Does Intensive Rehabilitation Permit Early Return to Sport without Compromising the Clinical Outcome after Arthroscopic Autologous Chondrocyte Implantation in Highly Competitive Athletes?

Background Despite improvement in treatment for articular cartilage lesions, prolonged recovery still precludes early return to competitive sports. The challenge of postoperative rehabilitation is to optimize return to preinjury activities without jeopardizing the graft. Hypothesis Intensive rehabilitation after second-generation arthroscopic autologous cartilage implantation (Hyalograft C) facilitates graft maturation and safely allows for early return to competition without jeopardizing clinical outcome at longer follow-up. Study Design Cohort study; Level of evidence, 3. Methods The outcome of 31 competitive male athletes with International Cartilage Repair Society grade III-IV cartilaginous lesions of the medial or lateral femoral condyle or trochlea were evaluated at 1-, 2-, and 5-year follow-up. The athletic cohort was compared with a similar control cohort of 34 nonathletic patients who were treated with autologous chondrocyte implantation. The athletic cohort followed a 4-phase intensive rehabilitation protocol. Eleven of the patients in this cohort were also treated with an isokinetic exercise program and on-field rehabilitation. The patients in the control cohort completed only phase 1 of rehabilitation. Results When comparing the 2 groups, a greater improvement in the group of athletes was achieved at 5-year follow-up (P = .037) in the self-assessment of quality of life and International Knee Documentation Committee subjective evaluation at 12 months and at 5 years of follow-up (P = .001 and P = .002, respectively). When analyzing the return to sports activity, 80.6% of the athletes returned to their previous activity level in 12.4 ± 1.6 months; athletes treated with the on-field rehabilitation and isokinetic exercise program had faster recovery and an even earlier return to competition (10.6 ± 2.0 months). Conclusion For optimal results, autologous chondrocyte implantation rehabilitation should not only follow but also facilitate the process of graft maturation. Intensive rehabilitation may safely allow a faster return to competition and also influence positively the clinical outcome at medium-term follow-up.
Major Galaxy Mergers and the Growth of Supermassive Black Holes in Quasars

Dusty Quasars Quasars are energetic sources thought to be fueled by matter accreting onto black holes a billion times more massive than the Sun. Some quasars are difficult to detect because of surrounding clouds of gas and dust, so much so that this population of objects has remained elusive. Based on a compilation of x-ray, optical, and mid-infrared data, Treister et al. (p. 600, published online 25 March; see the Perspective by Primack) show that the evolution of quasars across cosmic time occurs during mergers of gas-rich galaxies, with an obscured phase preceding an unobscured state by about 100 million years. Other objects have been detected in diverse wavebands, including ultraluminous infrared galaxies, which are known to be the product of similar gas-rich mergers of massive galaxies. Obscured and unobscured quasars represent two sequential phases of gas-rich mergers of massive galaxies. Despite observed strong correlations between central supermassive black holes (SMBHs) and star formation in galactic nuclei, uncertainties exist in our understanding of their coupling. We present observations of the ratio of heavily obscured to unobscured quasars as a function of cosmic epoch up to z ≅ 3 and show that a simple physical model describing mergers of massive, gas-rich galaxies matches these observations. In the context of this model, every obscured and unobscured quasar represents two distinct phases that result from a massive galaxy merger event. Much of the mass growth of the SMBH occurs during the heavily obscured phase. These observations provide additional evidence for a causal link between gas-rich galaxy mergers, accretion onto the nuclear SMBH, and coeval star formation.
Scheduling I/O requests with deadlines: A performance evaluation

The I/O scheduling problem is examined in detail. The authors present a realistic model for studying this problem in the context of a system which executes real-time transactions. The model takes advantage of the fact that reading from the disk occurs before a transaction commits, while writing to the disk usually occurs after the transaction commits. New algorithms are presented that exploit this fact in order to meet the deadlines of individual requests. The algorithms are evaluated via detailed simulation and their performance is compared with traditional disk scheduling algorithms. <<ETX>>
Subpolar Link to the Emergence of the Modern Equatorial Pacific Cold Tongue

Birth of the Cool Over the past 4 million years or so, tropical sea surface temperatures have experienced a cooling trend (see the Perspective by Philander). Herbert et al. (p. 1530) analyzed sea surface temperature records of the past 3.5 million years from low-latitude sites spanning the world's major ocean basins in order to determine the timing and magnitude of the cooling that has accompanied the intensification of Northern Hemisphere ice ages since the Pliocene. Martínez-Garcia et al. (p. 1550) found that the enigmatic eastern equatorial Pacific cold tongue, a feature one might not expect to find in such a warm region receiving so much sunlight, first appeared between 1.8 and 1.2 million years ago. Its appearance was probably in response to a general shrinking of the tropical warm water pool caused by general climate cooling driven by changes in Earth's orbit. The eastern Pacific Ocean cold tongue appeared as Earth’s climate cooled and subpolar waters expanded in the Pleistocene. The cold upwelling “tongue” of the eastern equatorial Pacific is a central energetic feature of the ocean, dominating both the mean state and temporal variability of climate in the tropics and beyond. Recent evidence for the development of the modern cold tongue during the Pliocene-Pleistocene transition has been explained as the result of extratropical cooling that drove a shoaling of the thermocline. We have found that the sub-Antarctic and sub-Arctic regions underwent substantial cooling nearly synchronous to the cold tongue development, thereby providing support for this hypothesis. In addition, we show that sub-Antarctic climate changed in its response to Earth’s orbital variations, from a subtropical to a subpolar pattern, as expected if cooling shrank the warm-water sphere of the ocean and thus contracted the subtropical gyres.
100-Million-Year Dynasty of Giant Planktivorous Bony Fishes in the Mesozoic Seas

From Big Fish to Big Whales Whales are the largest animals today, and many feed on the abundant plankton, particularly diatoms, in the oceans. Whales arose and diversified in the Cenozoic, about 30 to 40 million years ago (see the Perspective by Cavin). Marx and Uhen (p. 993) show that their diversity parallels the diversity of diatoms and changes in ocean temperature. Whether there were large predators of plankton before whales has been enigmatic, because the fossil record during the Mesozoic (245 to 65 million years ago) is sparse. Friedman et al. (p. 990) now show that a group of large fish filled this role for nearly 100 million years in the Mesozoic. Although not as large as whales, these globally distributed fish were still several meters long. Their extinction at the Cretaceous-Paleogene boundary 65.5 million years ago may have cleared the seas for the evolution of whales. The extinction of widespread large plankton-eating fish led to the emergence of whales in the Cenozoic. Large-bodied suspension feeders (planktivores), which include the most massive animals to have ever lived, are conspicuously absent from Mesozoic marine environments. The only clear representatives of this trophic guild in the Mesozoic have been an enigmatic and apparently short-lived Jurassic group of extinct pachycormid fishes. Here, we report several new examples of these giant bony fishes from Asia, Europe, and North America. These fossils provide the first detailed anatomical information on this poorly understood clade and extend its range from the lower Middle Jurassic to the end of the Cretaceous, showing that this group persisted for more than 100 million years. Modern large-bodied, planktivorous vertebrates diversified after the extinction of pachycormids at the Cretaceous-Paleogene boundary, which is consistent with an opportunistic refilling of vacated ecospace.
Extreme Deuterium Excesses in Ultracarbonaceous Micrometeorites from Central Antarctic Snow

Dust to Dust Interplanetary dust particles are thought to sample the most primitive materials in the solar system. Because of their large deuterium enrichments, they are thought to have formed in interstellar molecular clouds—the birthplaces of stars—and to predate the solar system. Duprat et al. (p. 742; see Perspective by Nittler) describe two large interplanetary dust particles collected from Antarctic snow. The particles contain large zones of organic matter with deuterium excesses 10 to 30 times the terrestrial value. Because the organic matter is associated with crystalline silicates similar to those formed within the solar accretion disk, it is expected that the particles themselves formed in the Sun's protoplanetary disk, contradicting the idea that all organics with deuterium excesses are of interstellar origin. Interplanetary dust particles recovered from Antarctic snow may provide a sample of the early solar system. Primitive interplanetary dust is expected to contain the earliest solar system components, including minerals and organic matter. We have recovered, from central Antarctic snow, ultracarbonaceous micrometeorites whose organic matter contains extreme deuterium (D) excesses (10 to 30 times terrestrial values), extending over hundreds of square micrometers. We identified crystalline minerals embedded in the micrometeorite organic matter, which suggests that this organic matter reservoir could have formed within the solar system itself rather than having direct interstellar heritage. The high D/H ratios, the high organic matter content, and the associated minerals favor an origin from the cold regions of the protoplanetary disk. The masses of the particles range from a few tenths of a microgram to a few micrograms, exceeding by more than an order of magnitude those of the dust fragments from comet 81P/Wild 2 returned by the Stardust mission.
Results about fast mutual exclusion

A fast mutual exclusion algorithm where only five accesses to the shared memory are needed in order to enter a critical section in the absence of contention is presented. In the presence of contention, the winning process may need to delay itself for 3* Delta time units, where Delta is an upper bound on the time taken by the slowest process to execute a statement involving an access to the shared memory. It is also proven that there is not two (or more) process mutual exclusion algorithm with an upper bound on the number of times a winning process needs to access the shared memory in order to enter its critical section in the presence of contention. However, under the assumption that busy-waiting counts as just one step, the authors present, for every fixed parameter k, an algorithm with the property that from a state where no process tries to enter its critical section, as long as the number of contenders does not exceed k, the time complexity of the winning process is a linear function of k. Finally, the ideas from the mutual exclusion algorithm are used to implement a fast and simple consensus algorithm. <<ETX>>
From cell to organism: the need for multiparametric assessment of exposure and biological effects

Radiation exposure produces a range of responses at every level of biological organisation. As new molecular, cellular, tissue, organ and organism responses are identified, it is essential to relate these responses to exposure parameters. This paper examines the use of different exposure parameters such as dose, fluence, local energy deposition, total energy deposited and hit number, and then relates them to biological responses at different levels of biological organisation. For many responses to high doses of radiation, the dose or energy concentration is the most appropriate and widely used parameter. The best predictor of response for cellular and molecular alterations following exposure to low radiation doses and for non-uniform radiation exposures appears to be “hit” number or the total energy deposited in the biological structure of interest. In many cases, this structure is the cell or the nucleus. To evaluate the probability of producing a cancer in an organ or tissue, the most appropriate measur.
Explaining Bird Migration

Predation pressure falls with increasing latitude, helping to explain why many birds migrate as far north as the high Arctic. Arctic shorebirds can travel tens of thousands of kilometers every year as they fly along intercontinental flyways from their southern wintering grounds to their remote, harsh breeding sites. How these birds solve the navigational and physiological constraints has been largely answered, but why they migrate is still a question with many possible answers (1). On page 326 of this issue, McKinnon et al. (2) present a continent-wide study that points to predation as a driving mechanism for migration. The study also elucidates the role of predation in shaping Arctic terrestrial biodiversity.
A Comparison of the Effect of Central Anatomical Single-Bundle Anterior Cruciate Ligament Reconstruction and Double-Bundle Anterior Cruciate Ligament Reconstruction on Pivot-Shift Kinematics

Background: Biomechanical differences between anatomical double-bundle and central single-bundle anterior cruciate ligament reconstruction using the same graft tissue have not been defined. Purpose: The purpose of this study was to compare these reconstructions in their ability to restore native knee kinematics during a reproducible Lachman and pivot-shift examination. Study Design: Controlled laboratory study. Methods: Using a computer-assisted navigation system, 10 paired knees were subjected to biomechanical testing with a standardized Lachman and mechanized pivot-shift examination. The navigation system recorded the 3D motion path of a tracked point at the center of the tibia, center of the medial tibial plateau, and center of the lateral tibial plateau with each maneuver. The testing protocol consisted of evaluation in the intact state, after complete anterior cruciate ligament transection, after medial and lateral meniscectomy, and after anterior cruciate ligament reconstruction with (1) a single-bundle center-center or (2) anatomical double-bundle technique. Repeated-measures analysis of variance with a post hoc Tukey test was used to compare the measured translations with each test condition. Results: A significant difference in anterior translation was seen with Lachman examination between the anterior cruciate ligament– and medial and lateral meniscus–deficient condition compared with both the double-bundle and single-bundle center-center anterior cruciate ligament reconstruction (P < .001); no significant difference was observed between reconstructions. The double-bundle construct was significantly better in limiting anterior translation of the lateral compartment compared with the single-bundle reconstruction during a pivot-shift maneuver (2.0 ± 5.7 mm vs 7.8 ± 1.8 mm, P < .001) and was not significantly different than the intact anterior cruciate ligament condition (2.7 mm ± 4.7 mm, P > .05). Discussion: Although double-bundle and single-bundle, center-center anterior cruciate ligament reconstructions appear equally effective in controlling anterior translation during a Lachman examination, analysis of pivot-shift kinematics reveals significant differences between these surgical reconstructions. An altered rotational axis resulted in significantly greater translation of the lateral compartment in the single-bundle compared with double-bundle reconstruction. Clinical Relevance: A double-bundle anterior cruciate ligament reconstruction may be a favorable construct for restoration of knee kinematics in the at-risk knee with associated meniscal injuries and/or significant pivot shift on preoperative examination.