Miracle-dz/UniFAR-FTUs huggingface dataset:
Relationship of maternal negative moods to child emotion regulation during family interaction

Abstract The relationship of maternal hostile and depressive moods to children's downregulation of unprovoked anger and sadness/fear was assessed in a community sample of 267 5-year-old boys and girls. The speed of children's downregulation of unprovoked anger and sadness/fear was based on real-time observations during mother–child interaction. The association of downregulation with maternal mood was estimated using Bayesian event history analysis. As mothers reported higher depressive mood, both boys and girls were faster to downregulate anger displays as those displays accumulated during mother child interaction. The speed of boys' downregulation of anger and of sadness/fear was not associated with maternal hostile mood. As mothers reported more hostile mood, girls were faster to downregulate displays of sadness/fear, but the speed of this downregulation slowed as those displays accumulated during ongoing mother–child interaction. These associations of child downregulation and maternal mood were observed after controlling for child adjustment. The data suggest frequent exposure to different negative maternal moods affect children's expression and regulation of emotions in relatively specific ways, conditional on the type of maternal mood, the type of child emotion, and child gender.
Evidence of Morocco Industry Long-Term Return Contrarian

In a landmark paper, Bornholt, Gharaibeh, and Malin (2015) show strong evidence of contrarian in the long-term returns of U.S. industries over formation periods (up to 132 months), this paper investigates whether there is evidence of contrarian in the long-term returns of 17 Morocco industries using monthly data covering the period from January 1995 to April 2014. This study finds strong evidence of long-term return contrarian in industry returns from strategy with long formation period lengths of 108, 120 and 132 months and this finding confirms the Bornholt et al. (2015) finding. The finding of this paper suggests that industry-level return contrarian is not simply a reflection of the stock-level contrarian. These contrarians are difficult to reconcile with overreaction.
Bowled Over by Cricket : Impact of Tape-Ball Injuries on the Eyes f

y , rl Purpose: The aim of this study was to describe the type and severity o tape-ball cricket–related eye injuries seen at a tertiary care hospital. Methods: This study included all cases of tape-ball cricket–related ey injuries presenting to the Section of Ophthalmology, Aga Khan Universit Hospital, Karachi, from January 2014 to January 2015. Results: A total of 20 patients with tape-ball cricket–related eye injurie were treated during this period. The right eye was involved in most (14/20 of the cases. The commonest presenting symptoms included reduce blurred vision, ocular pain, redness, and floaters. Sixty percent (12/20) o the affected eyes had a best corrected visual acuity of less than 20/200 presentation, with the retina being the most commonly involved ocul structure. All patients reported that they were not wearing protective ey wear at the time of trauma. Despite standard management, half of the eye had severe or total vision loss at the last follow-up (minimum, 3 months mainly due to retinal damage. Conclusions: Our study calls for the compulsory use of protective ey wear by cricket players and for countrywide surveillance data on the tru burden of this “unnoticed” preventable cause of unilateral eye injurie and associated vision loss.
Collection of hematopoietic CD34 stem cells in rhesus macaques using Spectra Optia

Nonhuman primates, particularly rhesus macaques, are ideal preclinical large animal models to investigate organ tolerance induction protocols using donor hematopoietic stem cells (HSCs) to induce chimerism. Their relatively small size poses some challenges for the safe and effective collection of peripheral blood HSCs through apheresis procedures. We describe our experiences using the Spectra Optia apheresis unit to successfully obtain HSCs from mobilized peripheral blood of rhesus macaques.
The Interplay of Family Systems, Social Networks and Fertility in Europe Cohorts Born Between 1920 and 1960

ABSTRACT Despite important variations in regional family systems, little research has been done to assess the effects of these differences on fertility and thus on families’ economic status. Even less attention has been paid to the effects of deviating from these regionally embedded norms in terms of network compositions. People's social networks may not conform to the region's view of the ideal family, while this could have important implications for their fertility behaviour. To fill this knowledge gap, this paper aims to answer two questions: to what extent do family systems shape family size, and to what extent do deviations from regional family system norms in terms of social network composition result in differences in completed fertility? To answer these questions, we use the first two waves of the ‘Survey of Health, Aging and Retirement’ and derive indicators describing regional family systems and people's social networks. We test the influence of these covariates on the completed fertility of cohorts born between 1920 and 1960 in 13 European countries. Our results show that family system norms, and deviations from them in terms of specific social networks, play an important role in determining family size.
Fiscal Policy and Inflation Targets: Does Credibility Matters?

We reconsider Svensson’s inflation-targeting proposal in a model where the need to raise seigniorage revenues determines the socially optimal inflation rate and distortionary taxes cause the inflation bias. Interpreting the targets as contracts, we show that the interaction between fiscal and monetary policy complicates the structure of the optimal contract. Moreover, if the commitment technology is imperfect, «highish» targets generate lower inflation than targets, which are too low to be credible. Alternatively, interpreting inflation targets as policy delegation to a non-distortionary target-conservative agent, we show that target-conservative bankers are public-expenditures conservative. Unfortunately, only idiosyncratic views about the benefits from public expenditures can be invoked to justify expenditures-conservatism, implying that target-conservative agents are also weight-conservative.
Does gamified elements influence on user’s intention to adopt and intention to recommend internet banking?

Purpose Understanding the main determinants of internet banking is important for banks and users. Although several prior research projects have focused on the factors that impact on adoption of technology, there is a limited empirical work which simultaneously captures technology-specific factors (PE, EE, WD, GAM) and customer-specific factors (GSC, INTRC) that help customers to adopt internet banking. Thus, the purpose of this paper is to verify how these factors influence individual behavior and motivate them to adopt new technology. The authors advance the body of knowledge on this subject by proposing moderating relationship of gamification between user’s intention to adopt and intention to recommend internet banking in social network. Design/methodology/approach To test the model the authors developed a quantitative study involving 398 internet users from five commercial banks. Data were collected in four weeks beginning of September 2017 from three large cities of Pakistan using convenience sampling approach. The theoretical model was tested using structural equation modeling (SEM). Findings The results indicate that intention to adopt internet banking is positively affected by performance expectancy, effort expectancy, website design, website characteristics and general self-confidence. Findings of SEM showed that approximately 72 percent of the variance in customer’s intention to adopt internet banking was accounted by predictors. Moderating effect of gamification suggested that the positive relationship between customer’s intention to adopt and customer’s intention to recommend internet banking will be stronger when gamification is higher. Importance performance matrix analysis (IPMA) suggested that among all other variables general self-confidence is the most important construct as it has the highest importance value in IPMA. Practical implications This study provides insightful guideline to practitioners, web designers and marketing professional that they should focus on both technology perspective and customer-specific factors to boost the confidence of internet banking users, while for researchers this study provides a basis for further development of technology adoption models in e-commerce domain. Originality/value This study contributes to the body of knowledge by adding game elements in technology perspective model and augments the e-commerce literature in the internet banking adoption context. To the date, this study is the first in its nature that investigates both technology-specific factors and customer-specific factors altogether to see the users influence toward technology adoption.
Variability in the Interpretation of Transmitted Genotypic HIV-1 Drug Resistance and Prediction of Virological Outcomes of the Initial Haart by Distinct Systems

High level HIV-1 drug resistance in recently infected treatment-naive individuals correlates with sub-optimal virological responses to highly active antiretroviral therapy (HAART). To determine whether genotypic HIV-1 drug resistance in chronic naive patients, as interpreted by various systems, could predict the virological outcomes of HAART, isolates from patients enrolled in a prospective observational cohort (ICoNA) prior to treatment start were genotyped. Genotypic susceptibility scores (GSS) assigned to the initial HAART regimens using the interpretations of pre-therapy resistance mutations by 13 systems were related to virological outcomes. Of 415 patients, 42 (10%) had at least one major resistance mutation. According to the different interpretations, 1.9–20.5% of patients had some level of resistance to at least one drug in the initial regimen. In multivariable analysis, GSS from two systems significantly predicted the time to virological success: Rega 5.5, for each unit increase in GSS adjusted relative hazard (RH) 1.86 [95% confidence intervals (95% CI): 1.15–3.02] and hivresistanceWeb v3, RH 1.87 (95% CI: 1.00–3.48). With three other systems, GSS showed a trend towards a significant prediction of success: Retrogram 1.6, RH 2.33 (95% CI: 0.98–5.53), Menéndez 2002, RH 2.36 (95% CI: 0.97–5.72) and Stanford hivdb, RH 2.06 (95% CI: 0.94–4.49). Genotypic resistance testing coupled with adequate interpretation in chronic naive patients can usefully identify those at risk of sub-optimal virological response to HAART.
Female Leadership Dilemmas in Primary Schools: A Case Study of 18 Primary Schools in Kambuzuma, Warren Park and Kuwadzana Areas of Harare Province in Zimbabwe

This case study qualitatively examined dilemmas that female school leaders in 18 predominantly female headed primary schools in Kambuzuma, Warren Park and Kuwadzana areas of Harare Province face. It used a purposive sample of 54 research participants comprising 12 female and six male heads, 14 female and four female deputy heads, and 18 female teachers-in-charge (TICs). The study found out that Zimbabwean women have been socially, politically, economically and culturally marginalised for a very long time. Female school leaders in spite of their high educational qualifications they raise children and manage homes. They also lacked the support of other fellow female subordinates. The study found out that social and cultural factors intervene to form a barrier to women advancement. The study concluded that female leaders were not as successful as male leaders in schools when it comes to the issues possession of charisma, expertise and staff motivational techniques. The study recommended that education systems should prove that they are gender sensitive by using a quota system throughout their recruitment and promotion policies. Finally, further studies on a much wider and larger scale should be held using quantitative and mixed research approaches in the capabilities between male and female school leaders who hold some educational qualifications and who are given equal opportunities.
Addressing Household Food Insecurity using the Household Food Insecurity Access Scale (HFIAS) in a Poor Rural Community in Sabah, Malaysia

Household food insecurity is defined as the lack of capability to produce food and to have access by all people at all times to enough food for an active and healthy life. The objective of this study was to evaluate household food insecurity status in Pitas town, Sabah, Malaysia. A sample of 102 households with the presence of mothers and at least one child between 1 and 5 years old were included. The respondents were interviewed with the use of a structured questionnaire to obtain information on their demographic, socioeconomic characteristics and dietary intake. 35.3% of the households were categorized as food secure, 28.4% as mildly food insecure, 27.5% as moderately food insecure and 8.8% as severely food insecure based on the Household Food Insecurity Access Scale (HFIAS) It is recommended that efforts to improve socio-economic status by enhancing the livelihood of the households in Pitas town need to be focused. More studies based on HFIAS scale should be carried out to generate more information in addressing household food insecurity among different ethnic groups in Malaysia.
Computer simulation of group Ia EPSPs using morphologically realistic models of cat alpha-motoneurons.

1. Morphological and electrophysiological data on the electrotonic structure of six triceps surae alpha-motoneurons and on the number and location of 202 Group Ia synapses making contact with ankle extensor motoneurons, previously obtained in this laboratory, were used to construct computer models to examine the generation of composite monosynaptic Group Ia excitatory postsynaptic potentials (EPSPs). 2. A total of 300 active synapses, each generating conductance transients based on voltage-clamp data and having activation times temporally dispersed (range approximately 1.3 ms) according to the conduction velocity profile of Group Ia-afferents, were used to generate composite EPSPs. 3. The shape indexes (foot-to-peak rise times and half widths) of simulated EPSPs matched those of experimentally observed Ia EPSPs reasonably well, although the rise times were, on average, approximately 0.25 ms longer in the simulated EPSPs. This may indicate that the effective temporal dispersion of actual Group Ia monosynaptic EPSPs is less than that the temporal asynchrony used in the simulations. 4. The peak amplitudes of simulated composite EPSPs (6-14 mV), as well as EPSPs produced by single somatic synapses (80-300 microV), were comparable to those found in experimental data. 5. Simulated EPSPs in motoneuron models with two forms of nonuniform Rm distribution ("step" increase from low values of Rm on the soma to much higher but uniform values in the dendrites, versus gradual monotonic "sigmoidal" increases from soma to distal dendrites) were similar in shape and amplitude. This prevented choosing one or the other Rm model as more "correct. " 6. Transmembrane voltages at synaptic sites in motoneuron dendrites during generation of composite Ia EPSPs had peak amplitudes less than twice those of the somatic EPSP. The amount of nonlinearity during EPSP production was assessed by making the delivery of synaptic current independent of the local transmembrane voltage. This non-linearity was modest (less than 10%) during composite EPSP generation, consistent with previous experimental evidence. 7. The local voltages produced in various parts of different dendrites during composite EPSP generation depended on the number and location of active synapses and on the electrotonic structure of the particular dendrite. The results show that dendrites that project in different directions away from the motoneuron soma could, in principle, exhibit different degrees of interaction between Ia and other synaptic inputs. 8. Although produced by the same number of active synapses, the simulated composite Ia EPSPs varied over a two-fold range of peak amplitude in relation to motor-unit type, cell input resistance, and cell size (total membrane area). (ABSTRACT TRUNCATED AT 400 WORDS)
Pengaruh Citra Merek dan Kualitas terhadap Kepuasan Konsumen melalui Keputusan Pembelian sebagai Variabel Intervening

The development of the business world that increasingly stringent demands companies should be able to move quickly and precisely to be able to face the competition. In fact become a leader in the market is not easy. Right marketing strategy is needed for the company to survive and compete with the hope to increase sales and customer satisfaction. Maintain the image and quality of the product is an attempt to attract purchases and customer satisfaction. This study aims to investigate the influence of brand image and quality to customer satisfaction through the purchase decision as an intervening variable. This study population are all consumers daily newspaper Suara Merdeka. Sampling by using incidental sampling technique, the number of respondents were 116 respondents. Data collection method used is the method of observation, interviews, and a questionnaire method. Path analysis Analyse the data using SPSS version 20, which used variables include brand image, quality, purchasing decisions and consumer satisfaction.
Herpes simplex virus type 1 DNA persistence, progressive disease and transgenic immediate early gene promoter activity in chronic corneal infections in mice.

We have used a mouse model system and the corneal route of inoculation to examine the issue of extra-neuronal persistence of herpes simplex virus type 1 (HSV-1). HSV-1 strain F DNA and inflammatory lesions were detected in corneal tissue of mice at 5, 11, 23, 37 and 60 days post-infection (p.i.) Viral DNA was localized by in situ PCR to epithelial cells and less frequently to cells in the stroma of the cornea. Viral proteins were not detected in the cornea and virus could not be isolated from tissue homogenates after 11 days p.i. even though histopathological lesions became progressively more severe at 37 and 60 days p.i. The DNA-containing cells were usually adjacent to the sites of inflammation or within these sites in the chronic stage (23, 37 and 60 days p.i.). In contrast to strain F, persistence of HSV-1 strain KOS DNA and inflammatory lesions were not detected after 11 days p.i. ; this result suggests that the long-term persistence of HSV-1 DNA and the development of inflammatory lesions are virus strain-dependent. We tested for the possibility of transgenic HSV-1 immediate early gene (ICP4) promoter activity in chronically infected corneas of transgenic mice containing the ICP4 promoter fused to the bacterial beta-galactosidase coding sequence. Our results indicated that the chimeric transgene was expressed in the cornea at 5, 11, 23, 37 and 41 days p.i. Possible explanations for these results and mechanisms for the generation of the chronic inflammatory lesions are discussed. The properties of chronic HSV infections in the cornea may be similar to those which have been described for persistent or defective viral infections in other systems.
In vitro cytotoxicity of nelarabine, clofarabine and flavopiridol in paediatric acute lymphoblastic leukaemia

The in vitro efficacies of three new drugs – clofarabine (CLOF), nelarabine (NEL) and flavopiridol (FP) – were assessed in a panel of acute lymphoblastic leukaemia (ALL) cell lines. The 50% inhibitory concentration (IC50) for CLOF across all lines was 188‐fold lower than that of NEL. B‐lineage, but not T‐lineage lines, were >7‐fold more sensitive to CLOF than cytosine arabinoside (ARAC). NEL IC50 was 25‐fold and 113‐fold higher than ARAC in T‐ and B‐lineage, respectively. T‐ALL cells were eightfold more sensitive to NEL than B‐lineage but there was considerable overlap. FP was more potent in vitro than glucocorticoids and thiopurines and at doses that recent phase I experience predicts will translate into clinical efficacy. Potential cross‐resistance of CLOF, NEL and FP was observed with many front‐line ALL therapeutics but not methotrexate or thiopurines. Methotrexate sensitivity was inversely related to that of NEL and FP. Whilst NEL was particularly effective in T‐ALL, a subset of patients with B‐lineage ALL might also be sensitive. CLOF appeared to be marginally more effective in B‐lineage than T‐ALL and has a distinct resistance profile that may prove useful in combination with other compounds. FP should be widely effective in ALL if sufficient plasma levels can be achieved clinically.
Evidence for early specialized processing of speech formant information in anterior and posterior human auditory cortex

Many speech sounds, such as vowels, exhibit a characteristic pattern of spectral peaks, referred to as formants, the frequency positions of which depend both on the phonological identity of the sound (e.g. vowel type) and on the vocal‐tract length of the speaker. This study investigates the processing of formant information relating to vowel type and vocal‐tract length in human auditory cortex by measuring electroencephalographic (EEG) responses to synthetic unvoiced vowels and spectrally matched noises. The results revealed specific sensitivity to vowel formant information in both anterior (planum polare) and posterior (planum temporale) regions of auditory cortex. The vowel‐specific responses in these two areas appeared to have different temporal dynamics; the anterior source produced a sustained response for as long as the incoming sound was a vowel, whereas the posterior source responded transiently when the sound changed from a noise to a vowel, or when there was a change in vowel type. Moreover, the posterior source appeared to be largely invariant to changes in vocal‐tract length. The current findings indicate that the initial extraction of vowel type from formant information is complete by the level of non‐primary auditory cortex, suggesting that speech‐specific processing may involve primary auditory cortex, or even subcortical structures. This challenges the view that specific sensitivity to speech emerges only beyond unimodal auditory cortex.
Medulloblastoma and Birth Date: Evaluation of 3 U.S. Datasets

Studies from Norway and Japan have found a higher incidence of medulloblastoma related to births that occur in the fall. The authors sought further evidence concerning this association. For 122 patients in a Duke University database and 90 patients from the Central Cancer Registry of North Carolina, the frequency distribution of birth dates by month was statistically significantly different from the expected North Carolina distribution (p = 0.04 and 0.06). For 75 patients from California Surveillance, Epidemiology, and End Results (SEER) data, the frequency distribution of birth dates by month was marginally different from the expected U.S. distribution (p = 0.14). For 922 patients from national SEER data, the frequency distribution of birth dates by month was not statistically significantly different from the expected U.S. distribution (p = 0.54). Subgroup analysis suggests seasonality of birth dates is most significant for patients aged 5-14 yr diagnosed with medulloblastoma.