Miracle-dz/UniFAR-FTUs huggingface dataset:
Méthodes asymptotiques pour le calcul des champs électromagnétiques dans des milieux à couches minces : application aux cellules biologiques

Dans cette these, nous presentons des methodes asymptotiques mathematiquement justifiees permettant de connaitre les champs electromagnetiques dans des milieux a couches minces heterogenes. La motivation de ce travail est le calcul du champ electrique dans des cellules biologiques composees d'un cytoplasme conducteur entoure d'une fine membrane tres isolante. Nous remplacons la membrane, lorsque son epaisseur est infiniment petite, par des conditions de transmission ou des conditions aux limites appropriees et nous estimons l'erreur commise par ces approximations. Pour les basses frequences, nous considerons l'equation quasistatique donnant le potentiel dont derive le champ. A l'aide d'un calcul en geometrie circulaire nous obtenons les expressions explicites du potentiel et nous en deduisons les asymptotiques du champ electrique, en fonction de l'epaisseur de la couche mince, avec des estimations de l'erreur. Nous estimons ensuite la difference entre le champ reel et le champ statique. Puis nous generalisons notre developpement asymptotique a une geometrie quelconque. La deuxieme partie de cette these traite des moyennes frequences : nous donnons le developpement asymptotique de la solution de l'equation de Helmholtz lorsque l'epaisseur de la membrane tend vers 0. Tous ces precedents resultats sont illustres par des calculs par elements finis. Enfin, pour les hautes frequences, nous construisons une condition d'impedance pseudodifferentielle permettant de concentrer l'effet de la couche sur son bord interieur. Nous concluons cette these par un probleme de diffraction a haute frequence d'une onde incidente par un disque de petite taille. A l'aide d'une analyse pseudodifferentielle, nous bornons la norme de la trace du champ diffracte a distance fixe de l'inhomogeneite en fonction de la taille de l'objet et de l'onde incidente.
Determinants of Bank Efficiency in Turkey: A Two Stage DataEnvelopment Analysis

Financial industry plays an important role in the economy and banks are indispensable players in the financial industry. Th erefore, the evaluation of banks' performance became a popular research topic in all over the world, and also in Turkey. There are different techniques to determine the banks' pe rformance. Among those techniques, Data Envelopment Analysis (DEA), which is a non-parametric technique, has been widely used in the banking sector. In this research, we analyzed t he efficiency of Turkish Banking Industry with Data Envelopment Analysis (DEA) methodology between 2002 and 2007. All the banks that constantly operated in the years between 2002 and 2007, excluding investment and development, participation banks, get into the anal ysis. So there are four groups of banks in the research, those are state-owned deposit banks, privately-owned deposit banks, foreign banks founded in Turkey, and foreign banks having branches in Turkey. In the research model, number of employees, interest expenses, non-interest expenses and total deposit are determined as input, total credits, interest revenu e and non-interest revenue are determined as output. This analysis aims to explain the variation in efficiency scores with a set of explanatory variables, such as size, ownership type , nationality, being publicly held. According to results, the efficiency levels do not change very much between 2002 and 2007. The efficiency scores reached top level in 2005 and 2006. The results of regression application denote that all of the explanatory vari ables have a significant effect on banks' efficiency levels. According to regression analysis results, size negatively affects the efficiency levels of banks. Publicly listed banks o perate more efficient than not publicly listed banks. Foreign owned banks operate more efficient t han their domestic peers. Furthermore, state owned banks are less efficient than non-state banks.
Milk yield, udder health and reproductive performance in Swedish organic and conventional dairy herds

Organic dairy farming is an expanding segment of the dairy sector where cow management differs from the conventional model in many respects. Thus, a comparative evaluation of disease and welfare status in organically and conventionally managed dairy cows is required. Assessment of milk yield, udder health and reproductive performance (RP) was done in 20 organically and 20 conventionally managed Swedish dairy herds. In accordance with earlier findings we confirmed lower milk yield in organic cows. Udder health and RP were chosen as indicators of animal health in view of their clinical relevance and the availability of appropriate data bases providing good background knowledge for further animal health assessment. No obvious differences were found in the investigations of somatic cell count (SCC) profiles or time to veterinary-treated cases of mastitis between organically and conventional managed cows. Pregnancy success at first insemination, an appropriate measurement of RP with biological interpretation and background, did not reveal any difference between management types, whereas the hazard rate-ratio (HR) of having a calving-interval was significantly lower (HR=0·71) in organically managed cows. The calving-interval is an important financial determinator in dairy production, but it is not considered an optimal indicator of biologic relevance as it partially reflects farmer decisions. In conclusion, the organically managed cows in this study did not differ from conventionally managed cows in udder health or RP, with the exception of calving interval.
The role of drug therapies in the treatment of anorexia and bulimia nervosa: a review of the literature

Conclusion Even if there have been useful researches on the efficacy of pharmacotherapy in the treatment of BN, there are still many unsolved issues regarding the optimal management of other EDs. Future directions for pharmacological treatment researches in EDs should include randomized controlled trials with different medications, inpatient versus outpatient trials and the assessment of medication effects for relapse prevention in recovered patients.
Fonctions métaboliques de Sirtuine 1 dans le muscle strié squelettique : contribution à l'étude de la régulation de l'expression de SREBP-1c et rôle potentiel lors d'un jeûne chez des myotubes C2C12

Sirt1 (Sirtuine 1) est une proteine histone deacetylase dependante de NAD+ qui stimule la neoglucogenese et inhibe la glycolyse dans le foie, et qui augmente l’oxydation des acides gras dans le muscle strie squelettique. Le but de ce travail de these a ete de definir les fonctions metaboliques de Sirt1 dans le muscle strie squelettique. Nous avons tout d’abord montre, a l’aide d’un modele de souris deficientes pour le gene Sirt1, que Sirt1 regulait l’expression de l’hexokinase II et de SREBP-1c, proteine regulatrice de l’expression de l’hexokinase. De plus, un modele d’electrotransfert de genes permettait de mettre en evidence que Sirt1 regulait l’expression de SREBP-1c de facon LXR dependante. Enfin, l’inhibition de Sirt1 par l’EX527 aboutissait a une diminution de la consommation de glucose chez des myotubes C2C12. Prises ensemble, ces donnees suggerent un role important de Sirt1 dans la regulation du metabolisme du glucose dans le muscle strie squelettique. Dans un second temps, nous avons determine le role potentiel de Sirt1 lors d’un jeune chez des myotubes C2C12. Un jeune entrainait une augmentation de l’activite cathepsine B + L et une dephosphorylation des proteines AktS473, GSK3S21/S9, p70S6KT412 et S6 S235/S236 qui precedait une amyotrophie des myotubes. La renutrition aboutissait a une rephosphorylation de ces proteines et a un retour a la normale de la taille des myotubes. L’activite cathepsine B + L restait cependant elevee. Enfin, le niveau en ARNm de Sirt1 etait augmente de facon transitoire lors de la renutrition. D’autres mesures de marqueurs des voies proteolytiques et de l’activite de Sirt1 sont a envisager. Nos donnees ainsi que celles de la litterature suggerent que Sirt1 pourrait avoir un role dans la regulation de l’autophagie lors du jeune. Pour conclure, ce travail de these met en evidence un role pour Sirt1 dans la regulation du metabolisme du glucose dans le muscle strie squelettique et apporte de nouvelles perspectives dans l’etude de la regulation de ce metabolisme en conditions pathologiques
Prognostic parameters in adult impalpable ultrasonographic lesions of the testicle.

PURPOSE Through an analysis of individual published data we assessed whether prognostic criteria exist for adult impalpable testicular sonographic lesions. MATERIALS AND METHODS We performed a bibliographic search on PubMed, MEDLINE, EMBASE online databases from 1990 to May 2004 using search words such as sonographic lesions of the testicle, impalpable tumors of the testicle and impalpable testicular lesions. Six articles were found that presented a description of the histological characteristics, patient age, lesion dimensions, presence of cryptorchidism and association with tumors in other parts of the body. A multivariate analysis was performed comparing the characteristics that appeared more interesting from a univariate analysis. RESULTS The characteristics of the 48 impalpable sonographic lesions were examined. Histologically 15 of the lesions were Leydig cell tumors (31%), 12 (25%) seminomas, 7 (14.5%) nonseminomatous germ cell tumors, 2 (4.5%) Sertoli cell tumors, 12 (25%) benign forms (fibrosis, infarct, lipoma, mesothelial hyperplasia, adenomatoid tumor). The average age was 37.5, average dimension was 10.11 mm. The lesions were hypoechoic in 85% of the cases. Of the patients 31% were infertile. Multivariate analysis showed that histological data were correlated with lesion dimensions and presence of infertility. Dimension was particularly related to germ cell tumors (for dimensions between 16 and 32 mm relative risk ratio [RRR] = 13.97, p=0.0449). Infertility proved significant in defining stromal tumors (RRR = 9,681, p=0.022) CONCLUSIONS Although with the limits of a retrospective study consisting in an analysis of individual data, interesting correlations between malignant pathologies and the initial characteristics of impalpable sonographic lesions were revealed. In particular an interesting correlation was found between the dimensions of the lesion and the malignant pathology and between Leydig cell tumor and infertility.
Pengaruh Cash Holding, Earning Per Share dan Nilai Perusahaan terhadap Income Smoothing

Abstract. This study aims to determine the effect of Cash Holding, Earning Per Share, and litigation risk to Income Smoothing. The method used in this research is descriptive research method, with quantitative approach. To propose the proposed hypothesis, this study used a sample of 13 mining companies listed in Indonesia Stock Exchange (IDX) period 2014-2017. The type of data used is secondary data, which is the financial statements of companies listing on the BEI. Hypothesis testing using multiple regression method with SPSS 22 software. The results of this study indicate the existence of Cash Holding, Earning Per Share, and litigation risk in Income Smoothing. For the purpose of further research to use other sector companies, Profitability and Stock Price. which may affect Income Smoothing. Keywords: Cash Holding, Earning Per Share, Company Value, Income Smoothing. Abstrak. Penelitian ini bertujuan untuk mengetahui pengaruh Cash Holding, Earning Per Share, dan Nilai Perusahaan terhadap Income Smoothing. Metode yang digunakan dalam penelitian ini adalah metode penelitian deskriptif, dengan pendekatan kuantitatif. Untuk menguji hipotesis yang diajukan, penelitian ini menggunakan sampel sebanyak 13 perusahaan sektor aneka industri yang listing di Bursa Efek Indonesia (BEI) periode 2014-2017. Jenis data yang digunakan adalah data sekunder, yang berupa laporan keuangan perusahaan yang listing di BEI. Pengujian hipotesis dilakukan menggunakan metode regresi berganda dengan software SPSS 22. Hasil dari penelitian ini menunjukkan bahwa Cash Holding, Earning Per Share, dan Nilai Perusahaan berpengaruh terhadap Income Smoothing. Untuk kegunaan penelitian selanjutnya untuk menggunakan perusahaan sektor lainnya, mengganti variabel independen lain seperti Profitabilitas dan Harga Saham. yang mungkin mempengaruhi Income Smoothing Kata Kunci: Cash Holding , Earning Per Share, Nilai Perusahaan, Income Smoothing
A Software Application to Streamline and Enhance the Detection of Fraud in Published Financial Statements of Companies

—Considerable effort has been devoted to the development of software to support the detection of fraud in published ﬁnancial statements of companies. Until the present date, however, the applied use of such research has been extremely limited due to the “black box” character of the existing solutions and the cumbersome input task they require. The application described in this paper solves both problems while signiﬁcantly improving performance. It is based on Web-mining and on the use of three Multilayer Perceptron where a modiﬁed learning method leads to the formation of meaningful internal representations. Such representations are then input to a features’ map where trajectories towards or away from fraud and other ﬁnancial attributes are identiﬁed. The result is a Web-based, self-explanatory, ﬁnancial statements’ fraud detection solution.
Immigration and suicidality in the young.

OBJECTIVES Little research has focused on the relation of immigration and suicidal behaviour in youth. Nevertheless, the impact of migration on the mental health of youth is an issue of increasing societal importance. This review aimed to present studies on the prevalence of suicidal behaviour in immigrant youth in various countries and to provide possible explanations for suicidal behaviour in immigrant youth, especially regarding acculturation. METHODS The review included a literature search to locate articles on the subject of suicidal behaviour in immigrant youth in the context of acculturation. RESULTS Studies on suicidal behaviour in culturally diverse youth are few and most of the existing research does not differentiate ethnic minorities from immigrants. Studies on epidemiology and on specific risk factors were found regarding various immigrant youth including Hispanics in the United States, Asians in North America and Europe, as well as comparative studies between different immigrant groups in specific countries. CONCLUSIONS The relation between immigration status and suicidal behaviours in youth appears to vary by ethnicity and country of settlement. Time spent in the new country as well as intergenerational communication and conflicts with parents have, in many of the studies, been related to suicidality in immigrant youth. Summing up, there is a clear and urgent need to further pursue the work in this field, to develop targeted public health interventions as well as psychosocial treatment for preventing suicide in these youth.
the dOuBle-edged sWORd OF negative in-gROup steReOtyping

The present work examined the negative consequences that result when stigmatized individuals endorse negative in-group stereotypes after failure. Study 1 found that women given the opportunity to blame their math failure on the stereotype “women are bad at math” showed higher stereotype endorsement, exerted less effort on a subsequent math test, and displayed less identification with the math domain. Study 2 found that observers’ felt more negative emotions toward a woman who blamed her poor per formance on the math stereotype. Furthermore, this effect was fully mediated by changes in perceptions of the woman’s confidence. Together, these findings suggest that people who use negative stereotypes to excuse their failures incur both personal and interpersonal costs.
Biodiversity and Productivity

The relationship between species richness and ecosystem productivity appears to be very complex. Researchers predict that human activities—especially landscape modification and climate change—will have a considerable impact on the distribution and abundance of species at local, regional, and global scales in the 21st century (1, 2). This is a concern for a number of reasons, including the potential loss of goods and services that biodiversity provides to people (3, 4). Exactly how biodiversity relates to ecosystem function and productivity, however, has been a widely studied and highly controversial issue over the past few decades. Initially, for example, many researchers believed that the relationship between species richness and net primary productivity (often expressed as the number of grams of carbon produced within a square meter of an ecosystem over a year) could be visualized as a hump-shaped or modal curve (5), with richness first rising and then declining with increasing productivity. However, subsequent theoretical and empirical research, including meta-analyses, seriously diminished acceptance of the modal pattern as a canonical relationship (6–11). On page 1750 of this issue, Adler et al. (12) carry the critique a step further. In a multiscale assessment of 48 plant communities on five continents, they demonstrate that the modal productivity-diversity pattern is quite rare in nature, rather than the dominant relationship. Their findings suggest that ecological understanding may advance more rapidly if investigators focus on exploring a range of topics that are germane to the productivity-diversity relationship in a changing world, rather than continue the search for a dominant pattern.
PbsP, a cell wall‐anchored protein that binds plasminogen to promote hematogenous dissemination of group B Streptococcus

Streptococcus agalactiae (Group B Streptococcus or GBS) is a leading cause of invasive infections in neonates whose virulence is dependent on its ability to interact with cells and host components. We here characterized a surface protein with a critical function in GBS pathophysiology. This adhesin, designated PbsP, possesses two Streptococcal Surface Repeat domains, a methionine and lysine‐rich region, and a LPXTG cell wall‐anchoring motif. PbsP mediates plasminogen (Plg) binding both in vitro and in vivo and we showed that cell surface‐bound Plg can be activated into plasmin by tissue plasminogen activator to increase the bacterial extracellular proteolytic activity. Absence of PbsP results in a decreased bacterial transmigration across brain endothelial cells and impaired virulence in a murine model of infection. PbsP is conserved among the main GBS lineages and is a major plasminogen adhesin in non‐CC17 GBS strains. Importantly, immunization of mice with recombinant PbsP confers protective immunity. Our results indicate that GBS have evolved different strategies to recruit Plg which indicates that the ability to acquire cell surface proteolytic activity is essential for the invasiveness of this bacterium.
The social network and the quality of life of people suffering from schizophrenia seven years after the first hospitalisation

andrzej Cechnicki1, Anna Wojciechowska1, Miguel Valdez2: Community Psychiatry Section, Chair of Psychiatry, Collegium Medicum, Jagiellonian University, 2 Departamento de Psiquiatria Universidad Autonoma de Nuevo Leon; Correspondence address: Andrzej Cechnicki: Community Psychiatry Section, Chair of Psychiatry, Collegium Medicum, Jagiellonian University, 2 Sikorskiego Pl. Apt. 8, 31-115 Cracow, Poland.
Intellectual Capital Disclosure and Firm Value: Does Jokowi’s Era Matter?

The purpose of this study is to observe the impact of Intellectual Capital Disclosure (Human Capital Disclosure, Structural Capital Disclosure, and Relational Capital Disclosure), Firm Size and Leverage towards the firm value (measured by Tobins Q). This study examines 36 Indonesias listed companies from infrastructure, utility, and transportation industry in 5 years period, from 2013 to 2017. The periods that have been chosen in order to differentiate the performance of 2 years before and 3 years of Joko Widodos era (Jokowi, President of Indonesia 2014-2019). Various results are found from the individual tests. None of the components from ICD has an influence on firm value during the pre-Jokowi�s era. The negative effect of RCD on firm value is found without differentiating the presidential era. In addition, the negative response from firm value is found when the interaction of ICD and the time period is increasing. This study conducts the content analysis of the IC disclosure in the annual reports, while it may not express the whole quality of IC practice. Furthermore, the company also may use other information channels than annual report to expose its IC performance. The restricted information of this study is driven by the sample size; therefore the extension of the type of industries could bring comprehensive results. Despite these limitations, this study contributes to the discussion about the appreciation of investors on the disclosures of IC and its components.
Desmopressin is a safe drug for the treatment of enuresis

Objective To verify the safety of desmopressin treatment and its associated side-effects in a large number of patients.Material and Methods The study was conducted in accordance with the guidelines of the Italian Club for Nocturnal Enuresis, whose criteria are: age >5 years; absence of malformations and infections of the urinary tract; absence of psychological disorders or neurological alterations; number of “wet nights” >5–7; control of liquid intake during the afternoon and evening; monitoring of serum electrolytes before beginning treatment; control of body weight before the beginning of treatment and during the first 4–5 days of therapy; and the informed consent of the parents. The therapeutic regimen provided for a maximum dose of desmopressin of 40 µg/day (four puffs/nostril or two tablets), starting from an initial dosage of 20 µg/day (two puffs/nostril or one tablet) 1 h before going to bed. The study involved two groups of patients with monosymptomatic enuresis: some of them had been administered desmopressin in the form of a spray and others in the form of tablets.Results A small percentage of patients presented mild, transient side-effects; in no case were severe side-effects verified.Conclusion Desmopressin is a safe drug with a low incidence of side-effects.