Miracle-dz/UniFAR-FTUs huggingface dataset:
Burnout in organizational settings.

Within the last decade, there has been a tremendous surge of interest in the problem of burnout. Although it was virtually unheard of prior to the late 1970s, It suddenly became a very popular topic. Hundreds of articles were written about it, as were numerous books; professional conventions held special sessions on it; and the mass media gave it extensive coverage. The general theme of all these discussions was that: (1) burnout is a problem, and (2) we need to do something about it. Consequently, there has been a tremendous proliferation of workshops, training materials, and organizational interventions planned by burnout consultants. Burnout has become big business. From our vantage point as researchers who have studied this topic extensively, these developments are cause for both applause and alarm. On one hand, we are pleased that this problem is finally getting some serious attention, after years of being Ignored or denied. On the other hand, we are concerned about the rush into solutions before there is full understanding of the problem. Research on burnout is still in its infancy, and there is much that we simply do not know about the phenomenon. For example, there is very little base rate information (e.g., what percentage of people experience burnout, and for how long), as well as a paucity of data on critical criterion outcomes, such as quality of work, turnover, and personal health (Maslach, 1983). Given the shortage of facts about burnout, it would be premature to give an authoritative answer about how to handle It. The picture is not entirely bleak, however. Even if it is not a lot, several things have been learned about burnout, as a result of studies by various researchers. Our own contributions to this state of knowledge have been: (1) the proposal of a mufti-faceted concept of burnout (Jackson & Maslach, 1982b; Maslach & Jackson, 1981b); (2) the development of a standardized instrument, the Maslach Burnout Inventory (MBI), to assess these different aspects of burnout (Maslach & Jackson, 1981a); and (3) the completion of several studies linking burnout to both work and family variables (Jackson & Maslach, 1982a; Maslach & Jackson,
Value of autonomic testing in reflex sympathetic dystrophy.

OBJECTIVE To attempt to characterize reflex sympathetic dystrophy (RSD) and to determine factors that would predict a response to sympathetic block. DESIGN We undertook a retrospective analysis on 396 patients with chronic limb pain referred for autonomic testing during a 5-year period. MATERIAL AND METHODS Clinical endpoints were relief of pain after sympathetic block and a composite RSD diagnostic probability score, based on the clinical attributes of allodynia, protopathia, swelling, and vasomotor alterations. We compared the results of three autonomic tests--resting sweat output (RSO), resting skin temperature (RST), and quantitative sudomotor axon reflex test (QSART). RESULTS Increased RSO predicted the diagnosis of RSD with 94% specificity, and the specificity was 98% when RSO was considered in conjunction with an abnormal QSART result, the best laboratory correlate (P = 0.003) of the clinical diagnosis. Shorter duration of pain correlated with a warmer limb (P < 0.001), even in the absence of RSD. Response to a single sympathetic block did correlate with the diagnosis (P = 0.031) but correlated most significantly with short duration of pain in the arm (P = 0.001) and laboratory findings in the leg, where increased RST (P < 0.001) and QSART (P < 0.001) were near-perfect predictors of response. CONCLUSION Sweating abnormalities correlate strongly with the clinical syndrome of RSD, and alterations in RST may be superior to clinical findings in predicting the response to sympathetic block. The findings provide physiologic support for the unproven view of a natural disease progression ("stages"), with better treatment response and a warmer extremity initially. Because certain physiologic trends occur in all patients, general alterations of autonomic function with pain are suggested.
Factors associated with the temporomandibular disorder, pain dysfunction syndrome (PDS): Manchester case-control study.

OBJECTIVES To determine the individual and combined effects of potential risk factors in relation to the temporomandibular disorder, Pain Dysfunction Syndrome (PDS). DESIGN Case-control study. MATERIAL AND METHODS Cases were new referrals to the temporomandibular disorder clinic of the University Dental Hospital of Manchester, diagnosed with PDS. Controls were randomly selected from 24 dental practices. Using a postal questionnaire information was collected on socio-demographic, local mechanical, psychological factors, co-morbidities and illness behaviour. The adjusted participation rate was similar in cases and controls (64%), and 131 cases and 196 controls finally participated in the study. RESULTS Compared with the controls, the cases were more likely to report that their teeth felt as though they did not fit together properly [odds ratio (OR) 8, 95% Confidence Interval (CI) 6-13] and report history of facial trauma (OR 3, 95% CI 2-6). Both diurnal and nocturnal grinding were significantly associated with PDS, and individuals who reported grinding their teeth both during the day and at night had a risk of 6; 95% CI 3-13 for PDS compared with those who did not. A history of orthodontic treatment, having any dentures, having missing teeth, use of chewing gum or biting the fingernails did not show any relationship with PDS. People who took medication for the bowels had a higher risk of PDS (OR 2, 95% CI 1-4). Participants with frequent headaches had a threefold increase in risk of having PDS (OR 3, 95% CI 2-5) while having pain in parts of the body other than the head was associated with an OR of 3 (95% CI 2-5). An increased propensity to have PDS was seen in those individuals with higher levels of psychological distress (OR 3; 95% CI 1-4 in the highest category, test for trend P < 0.001) and sleep disturbance (OR 5; 95% CI 2-94 in the highest category, test for trend P < 0.001). Aspects of illness behaviour, such as disease conviction (OR 4; 95% CI 2-9 in the highest category) and perception of illness (0.3; 95% CI 0.2-0.5) were associated with PDS. The result for the denial scale became statistically significant after adjustment for age and gender (2; 95% CI 1-3). CONCLUSIONS The current case-control study provides complementary epidemiological information on oro-facial pain (OFP) and supports a multifactorial aetiology of PDS, with factors from many domains, including local mechanical factors, psychological and co-morbidities. People with PDS were characterized by frequent headaches, history of facial trauma, teeth grinding, sleep problems, pain elsewhere in the body and high levels of psychological distress. From the results of current study and available evidence it seems inappropriate to consider PDS in isolation and future research should adopt a multidisciplinary approach to OFP.
Prospective Randomized Comparison Between a Dynamic Hip Screw and a Mini-invasive Static Nail in Fractures of the Trochanteric Area: Preliminary Results

Objectives This study aimed at comparing the results obtained with a sliding screw plate and an experimental device including a small-diameter nail that can be placed with a mini-invasive approach and provides a stable fixation. Design Randomized prospective study. Setting University hospital. Patients The study included two groups with thirty fractures of the trochanteric area. Interventions In both groups, the surgical procedure was carried out on patients placed on a traction table in a supine position, under an x-ray amplifier. Sliding screw plates (THS) were set in place according to the usual open technique. Nails were placed through a twenty-millimeter supratrochanteric cutaneous incision. This experimental system comprised a locked intramedullary nail with two nonparallel seven-millimeter cervicocephalic screws. Main Outcome Measures The comparison between the two groups was based on the surgical procedure (time, duration of x-ray irradiation, and total blood loss); the initial postoperative period (complications, duration of hospital stay, and the time before returning home); the time before full weight bearing became effective; the functional and social recovery; mortality; and the quality of immediate and final anatomic restitution and healing. Results Operating time (p < 0.001) and blood loss (p < 0.001) were lower in the nail group, and no blood transfusion was required. Postoperative pain (p < 0.01), time necessary to support full weight bearing (p < 0.02), and time before returning home (p < 0.05) were reduced in the nail group. All fractures healed in the same amount of time, with good anatomic results in the nail group, whereas ten impactions beyond ten millimeters occurred in the plate group. No difference was found between the two groups in walking ability and autonomy recovery, but hip function (p < 0.05) was better in the nail group. Conclusion This preliminary clinical study has shown the advantages of this mini-invasive technique. It could not evaluate all the possible disadvantages inherent in the method. These points will be evaluated in a multicenter study justified by these preliminary results.
Optimal Social Insurance and Health Inequality

Abstract This paper integrates into public economics a biologically founded, stochastic process of individual aging. The novel approach enables us to quantitatively characterize the optimal joint design of health and retirement policy behind the veil of ignorance for today and in response to future medical progress. Calibrating our model to Germany, our analysis suggests that the current social insurance policy instruments are set close to the (constrained) socially optimal levels, given proportional contribution rates for health and pension finance, the equivalence principle in the pension system, and a common statutory retirement age. Future progress in medical technology calls for a potentially drastic increase in health spending and a higher retirement age without lowering the pension contribution rate. Interestingly, from an ex ante point of view, medical progress and higher health spending are in conflict with the goal to reduce health inequality.
Occurrence of D-aspartic acid in rat brain pineal gland.

We found a high concentration (1030 pmol per pineal gland) of D-aspartic acid (D-Asp) in the pineal gland of 6-week-old Sprague-Dawley (SD) rats. The content of D-Asp decreased with age, being 210 and 33 pmol per pineal gland in 28- and 45-week-old rats respectively. The proportion of D-Asp [(D-Asp/total Asp) x 100] also decreased with age, declining from 66% to 10% between 6 and 45 weeks after birth. The proportion of D-Asp did not differ between the sexes. The concentration of D-Asp was higher at night (at 2.00 a.m. 2830 +/- 485 pmol per pineal gland) than during the day (at 10.00 a.m. 1030 +/- 200 and at 3:00 p.m. 682 +/- 194 pmol per pineal gland), suggesting that biosynthesis of D-Asp in the pineal gland occurs at night. D-Asp was found to be distributed in the cytosol of pinealocytes, but its biological role remains unclear.
KFU at CLEF eHealth 2017 Task 1: ICD-10 Coding of English Death Certificates with Recurrent Neural Networks

This paper describes the participation of the KFU team in the CLEF eHealth 2017 challenge. Specifically, we participated in Task 1, namely “Multilingual Information Extraction ICD-10 coding” for which we implemented recurrent neural networks to automatically assign ICD10 codes to fragments of death certificates written in English. Our system uses Long Short-Term Memory (LSTM) to map the input sequence into a vector representation, and then another LSTM to decode the target sequence from the vector. We initialize the input representations with word embeddings trained on user posts in social media. The encoderdecoder model obtained F-measure of 85.01% on a full test set with significant improvement as compared to the average score of 62.2% for all participants’ approaches. We also obtained significant improvement from 26.1% to 44.33% on an external test set as compared to the average score of the submitted runs.
Episodic fluctuations of serum gonadotropins in pre- and post-pubertal girls and boys.

The concentrations of LH and FSH were determined in serum samples obtained at 15 min intervals during a 4 h period from seven normal girls, 9.5-16.5 years of age, and eight normal boys, 9.0-16.8 years of age. An episodic pattern of LH secretion was found in all subjects. There was no significant (P greater than 0.1) difference between girls and boys as to number of episodes (3.0 +/- 0.6 vs. 3.0 +/- 0.0 per 4 h), absolute LH increase (2.6 +/- 1.1 vs. 2.4 +/- 1.0 mIU per ml) or "apparent LH half-life" (64.3 +/- 20.8 vs. 76.1 +/- 23.4 min). Mean absolute increase during secretory episodes correlated (R = 0.89, P less than 0.005) with the mean LH concentration per 4 h, and a significant (P less than 0.025) inverse correlation (R = -0.52) was found between the mean per cent increment of the LH secretory episode and the mean "apparent LH half-life. " Minor fluctuations of FSH were also observed. In girls and boys, the mean concentration of both gonadotropins increased with advancing puberty. The increase in LH concentration was due to an increase in the amplitude of secretory episodes rather than to an increase in the number of episodes. The increase in FSH concentration reflected a consistent elevation throughout the period of sampling.
Genomic Analysis of Tumor Microenvironment Immune Types across 14 Solid Cancer Types: Immunotherapeutic Implications

We performed a comprehensive immuno-genomic analysis of tumor microenvironment immune types (TMITs), which is classified into four groups based on PD-L1+CD8A or PD-L1+cytolytic activity (CYT) expression, across a broad spectrum of solid tumors in order to help identify patients who will benefit from anti- PD-1/PD-L1 therapy. The mRNA sequencing data from The Cancer Genome Atlas (TCGA) of 14 solid cancer types representing 6,685 tumor samples was analyzed. TMIT was classified only for those tumor types that both PD-L1 and CD8A/CYT could prefict mutation and/or neoantigen number. The mutational and neoepitope features of the tumor were compared according to the four TMITs. We found that PD-L1/CD8A/CYT subgroups could not distinguish different mutation and neoantigen numbers in certain tumor types such as glioblastoma multiforme, prostate adenocarcinoma, and head and neck and lung squamous cell carcinoma. For the remaining tumor types, compared with TIMT II (low PD-L1 and CD8A/CYT), TIMT I (high PD-L1 and CD8A/CYT) had a significantly higher number of mutations or neoantigens in bladder urothelial carcinoma, breast and cervical cancer, colorectal, stomach and lung adenocarcinoma, and melanoma. In contrast, TMIT I of kidney clear cell, liver hepatocellular, and thyroid carcinoma were negatively correlated with mutation burden or neoantigen numbers. Our findings show that the TMIT stratification proposed could serve as a favorable approach for tailoring optimal immunotherapeutic strategies in certain tumor types. Going forward, it will be important to test the clinical practicability of TMIT based on quantification of immune infiltrates using mRNA-seq to predict clinical response to these and other immunotherapeutic strategies in more different tumors.
Prevalence, Course, and Risk Factors for Antenatal Anxiety and Depression

OBJECTIVE: To estimate the prevalence and course of antenatal anxiety and depression across different stages of pregnancy, risk factors at each stage, and the relationship between antenatal anxiety and depression and postpartum depression. METHODS: A consecutive sample of 357 pregnant women in an antenatal clinic in a regional hospital was assessed longitudinally at four stages of pregnancy: first trimester, second trimester, third trimester, and 6 weeks postpartum. The antenatal questionnaire assessed anxiety and depression (using the Hospital Anxiety and Depression Scale) and demographic and psychosocial risk factors. The postpartum questionnaire assessed postpartum depression with the Edinburgh Postnatal Depression Scale. RESULTS: More than one half (54%) and more than one third (37.1%) of the women had antenatal anxiety and depressive symptoms, respectively, in at least one antenatal assessment. Anxiety was more prevalent than depression at all stages. A mixed-effects model showed that both conditions had a nonlinear changing course (P<.05 for both), with both being more prevalent and severe in the first and third trimesters. Risk factors were slightly different at different stages. Both antenatal anxiety (adjusted odds ratio [OR] 2.66, P=.004 in the first trimester; adjusted OR 3.65, P<.001 in the second trimester; adjusted OR 3.84, P<.001 in the third trimester) and depression (adjusted OR 4.16, P<.001 in the first trimester; adjusted OR 3.35, P=.001 in the second trimester; adjusted OR 2.67, P=.009 in the third trimester) increased the risk of postpartum depression. CONCLUSION: Antenatal anxiety and depression are prevalent and serious problems with changing courses. Continuous assessment over the course of pregnancy is warranted. Identifying and treating these problems is important in preventing postpartum depression. LEVEL OF EVIDENCE: II
Initial occurrence of Taylorella asinigenitalis and its detection in nurse mares , a stallion and donkeys in Kentucky

In 1998, a newly identified bacterium Taylorella asinigenitalis was isolated from the external genitalia and reproductive tracts of nurse mares, a stallion and donkey jacks in Kentucky. An extensive regulatory effort was implemented to contain the outbreak including the tracing and testing of 232 horses and donkeys on 58 premises. T. asinigenitalis was isolated from the reproductive tract of 10 adult equids, including two donkey jacks, one Paint Quarter-horse stallion and seven draft-type breeding mares. None of the infected horses had clinical signs Equine Taylorella asinigenitalis
“Siéntete un cyborg” Sistema demostrativo del funcionamiento de un robot

Este documento presenta un sistema de monitorizacion y telecontrol de una plataforma movil robotica utilizando una conexion inalambrica Bluetooth. Se ha disenado una aplicacion con una interfaz de usuario atractiva y sencilla de manejar, que permite a una persona interactuar con un robot en tiempo real y de forma remota. Este sistema es una herramienta para acercar el mundo de la robotica a personas con diferentes niveles de conocimiento, puesto que permite explicar de forma sencilla los diferentes elementos que forman un robot, asi como su funcionamiento y su interaccion con el entorno. El sistema tambien puede ser utilizado como herramienta didactica para practicas de asignaturas donde se estudien Sistemas Empotrados, LabView y Robotica Basica.
Design of a Two-Channel NMR Coil Using an Impedance Transformation Approach

In the field of small-animal magnetic resonance imaging, multi-channel coils are increasingly being used. Two-channel coils based on a common conductor between the two elements are not considerably used and theoretical equations are not explicitly given. In this paper, the design of a two-channel nuclear magnetic resonance coil based on common conductor for imaging applications has been carried out using an impedance transformation approach. The equations and simulations result at an operating frequency of 300 MHz are confirmed by the characterization of the two-channel receiver coil prototype.
Application of Principal Component Factor Analysis in Quantifying Size and Morphological Indices of Domestic Rabbits

Los objetivos de la investigacion fueron determinar el peso corporal y cuatro rasgos morfoestructurales denominados longitud corporal, circunferencia cardiaca, circunferencia del muslo y longitud de la oreja de 103 mestizos de conejos blancos de Nueva Zelanda x Chinchilla. Ademas, describir la interdependencia entre los rasgos de conformacion y predecir el peso corporal desde los resultados de sus factores independientes mediante el analisis de los componentes principales. Correlaciones fenotipicas entre el peso corporal y las dimensiones corporales fueron altamente significativas (r = 0,61 - 0,91; P <0,01). Correlaciones pareadas de los caracteres de la forma del cuerpo variaron de valores moderados a altos. Fueron extraidos dos componentes principales, desde elanalisis factorial con rotacion Varimax de los rasgos intercorrelacionados, que representan el 90,27% de la varianza total. El primer componente principal, denominado tamano general PC1, tiene su carga para longitud corporal, circunferencia cardiaca y circunferencia del muslo y explican el 74,98% de la varianza. La longitud de la oreja determina principalmente el segundo componente principal, PC2 que contribuyo al 15,29% de la varianza generalizada. Los caracteres ortogonales de la forma del cuerpo derivados del analisis factorial representaron el 81,7% de la variacion en el peso corporal de los conejos. Para la seleccion de animales para un optimo balance, el PC basado en modelos de prediccion es preferible a los basados en modelos de medicion lineal ya que combina el tamano y componentes de la forma en un indice compuesto para prediccion.
Effect of Ankle Joint Contact Angle and Ground Contact Time on Depth Jump Performance

Abstract Phillips, JH and Flanagan, SP. Effect of ankle joint contact angle and ground contact time on depth jump performance. J Strength Cond Res 29(11): 3143–3148, 2015—Athletes often need to both jump high and get off the ground quickly, but getting off the ground quickly can decrease the vertical ground reaction force (VGRF) impulse, impeding jump height. Energy stored in the muscle-tendon complex during the stretch-shortening cycle (SSC) may mitigate the effects of short ground contact times (GCTs). To take advantage of the SSC, several coaches recommend “attacking” the ground with the foot in a dorsiflexed (DF) position at contact. However, the efficacy of this technique has not been tested. This investigation tested the hypotheses that shorter GCTs would lead to smaller vertical depth jump heights (VDJH), and that this difference could be mitigated by instructing the athletes to land in a DF as opposed to a plantar flexed (PF) foot position. Eighteen healthy junior college athletes performed depth jumps from a 45-cm box onto force platforms under instruction to achieve one of the 2 objectives (maximum jump height [hmax] or minimal GCT [tmin]), with one of the 2 foot conditions (DF or PF). These variations created 4 distinct jump conditions: DF-hmax, DF-tmin, PF-hmax, and PF-tmin. For all variables examined, there were no significant interactions. For all 4 conditions, the ankle was PF during landing, but the DF condition was 28.87% less PF than the PF condition. The tmin conditions had a 23.48% shorter GCT than hmax. There were no significant main effects for jump height. The peak impact force for tmin was 22.14% greater than hmax and 19.11% greater for DF compared with PF conditions. A shorter GCT did not necessitate a smaller jump height, and a less PF foot did not lead to improvements in jump height or contact time during a depth jump from a 45-cm box. The same jump height was attained in less PF and shorter GCT conditions by larger impact forces. To decrease contact time while maintaining jump height, athletes should be instructed to “get off the ground as fast as possible. ” This cue seems to be more important than foot position. However, it should be acknowledged that this technique leads to larger impact forces, which should be considered when prescribing the number of foot contacts in a plyometrics program. The ability of athletes to truly land in a DF position during depth jumps is questioned and needs further investigation.