Miracle-dz/UniFAR-FTUs huggingface dataset:
Continuum approximation to fullerene molecules.

The electronic and elastic properties of large fullerene molecules are studied. The low-lying electronic levels are described by the Dirac equations in (2+1) dimensions, and the intramolecular modes are given by the theory of elasticity. Coupling between electrons and phonons can also be written in a simple way. The quantum dynamics of the ions is modified by the appearance of nontrivial Berry's phases. The qualitative features of fullerenes with elliptical and cylindrical geometries, and minimal surfaces with negative curvature are also studied
Mechanisms of Hypothalamic‐Pituitary‐Adrenal Axis Stimulation by Immune Signals in the Adult Rat a

Abstract: Immune stimulation increases the activity of the HPA axis, a phenomenon directly or indirectly mediated through cytokines. We have used two models, the peripheral administration of endotoxin (LPS) or turpentine‐induced tissue injury to show that corticotropin‐releasing factor (CRF) and vasopressin (VP), hypothalamic peptides released by cytokines, play a dominant role in the increased ACTH measured in these two paradigms. In turn, CRF and VP synthesis and/or release is modulated by catecholamines, prostaglandins (PGs), and nitric oxide (NO). These secretagogues are produced in the periphery and/or the central nervous system (CNS) in response to increased cytokine levels and act on CRF/VP neurons and nerve terminals. Finally, endotoxemia and local tissue inflammation may upregulate brain levels of tumor necrosis factor α, interleukin‐1β, and/or interleukin‐6, providing yet another mechanism through which the occurrence of systemic inflammation is conveyed to the brain. The relative importance of brain or peripheral intermediates appears to depend on the site at which cytokine levels are increased. We have shown, for example, that peripheral, but not brain, PGs are important in mediating the neuroendocrine influence of blood‐borne cytokines, while PGs in the CNS play a role in situations characterized by elevated brain immune proteins. NO, on the other hand, restrains the response of the HPA axis to circulating, but not brain cytokines. These results illustrate the complexity of the mechanisms involved in the stimulation of the HPA axis and suggest that their specific involvement depends on the type, intensity, and duration of immune stimulation.
Polar hydrogen positions in proteins: Empirical energy placement and neutron diffraction comparison

A method for the prediction of hydrogen positions in proteins is presented. The method is based on the knowledge of the heavy atom positions obtained, for instance, from X‐ray crystallography. It employs an energy minimization limited to the environment of the hydrogen atoms bound to a common heavy atom or to a single water molecule. The method is not restricted to proteins and can be applied without modification to nonpolar hydrogens and to nucleic acids. The method has been applied to the neutron diffraction structures of trypsin ribonuclease A, and bovine pancreatic trypsin inhibitor. A comparison of the constructed and the observed hydrogen positions shows few deviations except in situations in which several energetically similar conformations are possible. Analysis of the potential energy of rotation of Lys amino and Ser, Thr, Tyr hydroxyl groups reveals that the conformations of lowest intrinsic torsion energies are statistically favored in both the crystal and the constructed structures.
An Avirulent Ralstonia Solanacearum Strain Undergoes Phenotype Conversion from a Pathogenic Strain Under Natural Environment

An avirulent R. solanacearum strain named FJAT-1458 was isolated from living tomato vessel and it showed no toxicity to tomato, pepper and eggplant. Multilocus sequence analysis (MLSA) based on eight genes (egl, hrpB, mutS, pehA, recA, rpoA, rpoB and rpoC) and whole genome average nucleotide identity (ANI) analysis suggested that strain FJAT-1458 belong to phylotype I. Genome sequence of the strain FJAT-1458 revealed a circular chromosome and a circular megaplasmid with whole genome size of 6,059,899 bp and GC content of 66.78%. Functional annotation of FJAT-1458 showed a total of 5,442 genes, with 5,166 protein-encoding genes, 202 pseudogenes and 74 noncoding RNA genes. Among which, 3,938 protein-coding genes can be assigned to 23 COG families, and 1,521 of them had KEGG orthologs. Prophage prediction using PHASTER revealed 12 prophages, including 7 intact, 1 questionable and 4 incomplete prophages. Comparative genome analyses between GMI1000 and FJAT-1458 showed that most of the virulence factors were well conserved and only small portion of them were distinct between them. Two genes, including a methyltransferase and an ISL3 family transposase genes, were identified to be inserted immediately upstream (141 bp) of phcA gene, which assumed to be responsible for avirulence of strain FJAT-1458. It is suggested that strain FJAT-1458 was originated from a wild-type pathogenic strain through an accident phenotype conversion, which is like those when cultured under experimental conditions. Our study provides new insight into the evolution of virulence in R. solanacearum strain under natural environment.
Convective Impact on Temperatures Observed near the Tropical Tropopause

Abstract Observed temperature trends and interannual variations near the tropical tropopause suggest that temperatures up to the cold point are controlled by the troposphere, but some models indicate otherwise. Here, previous investigations of thermal anomalies and heating profiles associated with tropical convective outbreak are extended, by examining behavior near the tropopause. Observations show that active convective systems are locally associated with warm anomalies in the upper troposphere but cold anomalies in the lower troposphere and near the tropopause. Time-dependent solutions of Laplace's equations demonstrate that the cold anomaly below 100 hPa can be, at least partly, accounted for by adiabatic lofting associated with a transient heating pulse at lower levels. However, detailed examination of the cold-point tropopause in the data reveals that it moves against the lofting, downward toward higher pressure and colder potential temperatures, in response to convection. These variations qualitati.
Do Fire Sales Create Externalities?

We develop three novel measures of how much of the price impact of their trading different mutual funds internalize. We show that mutual funds that internalize more of their price impact hold larger cash buffers and use these buffers more aggressively to accommodate inflows and outflows. As a result, stocks held by these funds have lower volatility, and flows out of these funds have smaller spillover effects on other funds holding the same securities. Our results provide evidence of meaningful fire sale externalities in the mutual fund industry.
Farmers Willingness to Share Data: A Study of Saskatchewan Farmers

Modern farm machinery captures geocoded data on all aspects of a farming operation. These detailed datasets are called big data. Although some of this data is useful to individual farmers, much of it has little value to the farmer that collects it. Capturing the true value of big data comes when it is aggregated over many farms, allowing researchers to find underlying trends. To analyze farmers willingness to share data we conduct a hypothetical choice experiment that asked farmers in Saskatchewan whether they would join a big data program. The choice tasks varied the type of organization that operated the big data program, and included financial and non-financial incentives. Heteroscedastic and random effects probit models are presented using data from a survey constructed for this study. The results are consistent across models and find that farmers are most willing to share their data with university researchers, followed by crop input suppliers or grower associations, and financial institutions or equipment manufacturers. Farmers are least willing to share their data with government. Farmers are more willing to share data in the presence of a financial incentive or non-financial incentive such as comparative benchmark statistics or prescription maps generated from the data submitted. Acknowledgement :
Recovery from Acidification in European Surface Waters: A View to the Future

Abstract There is now overwhelming documentation of large-scale chemical recovery from surface water acidification in Europe, but to date there has been little documentation of biological recovery. Modelling studies based on current emission reduction plans in Europe indicate that there will be further chemical recovery. The uncertainties in these scenarios mainly relate to the future behavior of nitrogen in the ecosystem and the effects of climate change. Four major climate-related confounding factors that may influence the chemical and biological recovery process are: i) increased frequency and severity of sea-salt episodes; ii) increased frequency and severity of drought; iii) in-creased turnover of organic carbon; iv) increased mineralization of nitrogen. International cooperative work to abate acidification has so far been very successful, but there is still a long way to go, and many potential setbacks. It is essential that future development of water chemistry and aquatic biota in acidified waterbodies continue to be monitored in relation to further emission reductions of S and N and future effects of climate change.
An Effective Data Privacy Mechanism through Secure Session Key Exchange Model for MANET

Data privacy in the mobile ad-hoc network is a problem due to wireless medium, frequent node movement and lack of any centralized infrastructure support. In such case, it is very important to build a reliable and secure network and achieve high throughput in MANET. The reliability and security of a network depend on whether the network remains linked to different failures and malicious activities, which is the fundamental issue that needs to be focused when designing a secure routing protocol in MANET. This paper proposes an effective privacy mechanism to handle data security through a novel secure session key exchange model, which provides the node data privacy and network stability for a longer period of time and prevents abnormal behavior changes due to malicious behavior and different type of attacks in the network. The simulation results show improvement in throughput with nominal overhead and end-to-end delay in different malicious conditions against existing protocols.
Corporate governance and firm performance: Evidence from an emerging market

The paper investigates the link between corporate governance scores and firm performance among the largest 90 listed companies on the Saudi Stock market. The sample of 90 listed firms is split into two samples: firms with high governance scores and firms with low governance scores. The research compares and contrasts the operating performance of the two samples. In addition, regression models are used to test the link between governance scores and performance. No link between the companies’ corporate governance scores and operating performance is found. It is difficult to capture all elements of the complex corporate governance topic in corporate governance scores. It seems that corporate governance in emerging markets lags far behind that of developed markets. This is the first paper to examine the link between corporate governance scores and operating performance in the Saudi market, a new emerging market that has not been examined. The paper adds to the debate in the literature whether there is a link between corporate governance scores and performance. The evidence in the literature is inconclusive.
Cachectin: more than a tumor necrosis factor.

THE metabolic impact of infectious and neoplastic disease states has long been known to clinicians.1 2 3 4 Invasive diseases may disrupt normal homeo-static mechanisms, both locally and systemically. For example, acute gram-negative infections frequently lead to profound metabolic acidosis and to biphasic changes in plasma glucose concentration, both seen in the context of hypotension, disseminated intravascular coagulation, and widespread tissue injury.5 6 7 8 9 10 11 12 Chronic infectious diseases, as well as neoplastic diseases, may provoke a severe wasting diathesis, in which negative calorie and nitrogen balance lead to death despite the absence of a large parasite or tumor burden. It was once widely believed that invasive .
Three-year clinical comparison of survival of endodontically treated teeth restored with either full cast coverage or with direct composite restoration.

STATEMENT OF PROBLEM Little information exists regarding the outcome of crown build-ups on endodontically treated teeth restored with metal-ceramic crowns or with only a direct-placed composite. PURPOSE The aim of this study was to evaluate the clinical success rate of endodontically treated premolars restored with fiber posts and direct composite restorations and compare that treatment with a similar treatment of full-coverage with metal-ceramic crowns. MATERIAL AND METHODS Subjects included in this study had one maxillary or mandibular premolar for which endodontic treatment and crown build up was indicated and met specific inclusion/exclusion criteria. Only premolars with Class II carious lesions and preserved cusp structure were included. Subjects were randomly assigned to 1 of the following 2 experimental groups: (1) teeth endodontically treated and restored with adhesive techniques and composite or (2) teeth endodontically treated, restored with adhesive techniques and composite, and then restored with full-coverage metal-ceramic crowns. Sixty teeth were included in the first group and 57 in the second. All restorations were performed by one operator. Causes of failure were categorized as root fracture, post fracture, post decementation, clinical and/or radiographic evidence of marginal gap between tooth and restoration, and clinical and/or radiographic evidence of secondary caries contiguous with restoration margins. Subjects were examined for the listed clinical and radiographic causes of failure by 2 calibrated examiners at intervals of 1, 2, and 3 years. Exact 95% confidence intervals for the difference between the 2 experimental groups were calculated. RESULTS At the 1-year recall, no failures were reported. The only failure modes observed at 2 and 3 years were decementations of posts and clinical and/or radiographic evidence of marginal gap between tooth and restoration. There was no difference in the failure frequencies of the 2 groups (95% confidence interval, -17.5 to 12.6). There was no difference between the number of failures caused by post decementations and the presence of marginal gaps observed in the 2 groups (95% confidence intervals, -9.7 to 16.2 and -17.8 to 9.27). CONCLUSION Within the limitations of this study, the results upheld the research hypothesis that the clinical success rates of endodontically treated premolars restored with fiber posts and direct composite restorations after 3 years of service were equivalent to a similar treatment of full coverage with metal-ceramic crowns.
Pulsed dye laser-mediated photodynamic therapy for acne inversa is not successful: A pilot study on four cases

The relapses and the chronicity of acne inversa cause a significant impact on the quality of life of the affected patients and urge for a search of more effective treatments. We report the treatment of four consecutive acne inversa patients with pulse dye laser-mediated photodynamic therapy (PDL-PDT). Three months after the end of the treatment there was no improvement in comparison with opposite control sites. Intense pain during treatment was reported by all the patients. These cases do not support the use of PDL-PDT for treating acne inversa.
Disease‐modifying drug therapies

The development of the disease modifying drug, riluzole, is changing the natural history of amyotrophic lateral sclerosis (ALS). Let us take the ‘classic’ ALS patient as portrayed by ALS CARE-Wisconsin (Tables 1 and 2). When ALS patients come to see us, many are already on vitamin E, as we have seen in our clinic population, and then within a short period of time they are put on a number of therapies. The main one is, of course, riluzole, the only approved disease-modifying agent for ALS at this time (Figures 1 and 2).
Pengaruh Belanja Modal, Intergovernmental Revenue, Leverage, Size dan Pendapatan Alsi Daerah Terhadap Kinerja Keuangan Pemerintah Daerah Kota dan Kabupaten di Pulau Jawa Tahun 2014

The emergence of MPR Decree No. XV/MPR/1998 on "Implementation of Autonomous Regions, Distribution and Utilization of National Resources Fair Indonesia" has responsibility for local government that is big enough. Responsibility is one of them can be evidenced by the performance of pemerinrah area. Performance is the picture of the achievement of the vision, mission, and goals of an organization. This research was conducted in order to obtain empirical evidence related to the effect of capital expenditures, the intergovernmental revenue, size, leverage and local revenues on the financial performance of local governments. The population of this research is all local government district / city island of Java in fiscal year 2014. The total sample of this research are 43 local government district / city are taken by using purposive sampling. Data were analyzed using multiple linear regression analysis results showed that capital spending and intergovernmental revenue significantly influence the financial performance of local government districts / cities in Java. As for size, leverage and local revenues do not affect the financial performance of local government districts / cities in Java.
Clonal reproduction by males of the ant Vollenhovia emeryi (Wheeler)

In colonies of the queen‐polymorphic ant Vollenhovia emeryi, some colonies produce only long‐winged (L) queens, while others produce only short‐winged (S) queens. At four nuclear microsatellite loci, males in the S colony had alleles that were different from those of their queen. This suggests that the nuclear genome of males is not inherited from their colony queen, as has also been described for Wasmannia auropunctata (Roger). In V. emeryi the possibility of male transfer from other colonies has not been ruled out because previous studies of this species have obtained only nuclear gene information. We analyzed both mitochondrial and nuclear genes for S queens, S males and L queens to clarify the origins of males. Sequence analyses showed that although S queens and S males shared the same mtDNA haplotype, they had a different genotype at a nuclear gene (long‐wavelength opsin) locus. Neighbor‐joining analysis based on the four microsatellite loci also suggested gene pool separation between S queens and S males. These results are consistent with predictions of clonal reproduction by males. While L queens share opsin genotypes with S males, they have very different mtDNA sequences. Hybridization in the near past between S queens and L males or gene transmission from S males to L queen populations in the present would explain these differences.
Consumers' Trust of Multi-Attribute Experience-Goods Seller

A monopolist sells experience goods with observable and experience attributes. The attributes are termed complements (substitutes) if an increase in one attribute raises (lowers) the marginal value of the other. Deviation in quality takes two periods to complete, possibly causing a V-shaped quality trend. The equilibrium observable attribute increases (decreases) in the seller's discount factor when the two attributes are complements (substitutes). For pure experience goods, turning one experience attribute observable can lower the remaining experience attribute and profit. Commitment of the observable attribute promotes consumers' trust and raises profit, but exogenously-imposed minimum quality standard can hamper trust when attributes are substitutes.
Prevalence of coeliac disease and relations to Helicobacter pylori infection and duodenitis in a Swedish adult population sample: a histomorphological and serological survey

AbstractAim: The aim of this study was to determine the prevalence of coeliac disease and its relation to duodenitis, H. pylori infection and gastritis in a sample of the adult general population. Methods: A Swedish population sample of 482 subjects (aged 35 to 85 years) were examined with gastro-duodenoscopy with multiple biopsies taken. Circulating antibodies to endomycium, gliadin, and H. pylori were also determined. Results: Based on histomorphological findings, coeliac disease was evident in 9 of 482 subjects giving a prevalence of 1.9 [1.0-4.0, 95% confidence interval] percent. The prevalence of gastritis with or without H. pylori infection did not differ between subjects with and without coeliac disease. Considering subjects without coeliac disease, there was no difference in the serum levels of gliadin antibodies between those with and without duodenitis. However, subjects with positive H. pylori status had significantly higher levels of gliadin antibodies than those with negative H. pylori status. Conclusions: This study confirms that there is a relatively high prevalence of undiagnosed coeliac disease in Swedish adults. There was no association between coeliac disease and H. pylori infection or gastritis, although serum gliadin antibody levels were slightly increased in subjects with positive H. pylori status.
Inversion of the attenuated Radon transform for non-parallel geometries

In this work, we first introduced a reorganized form of the Novikov's inversion formula for the attenuated Radon transform with parallel-beam geometry which utilizes the conventional filters (such as the Shepp-Logan, Hanning, etc.) to simplify image reconstruction procedures. Then we developed an accurate reconstruction method for non-parallel beam geometries. The method contains three major steps: (1) one-dimensional rebinning using phase-shifting technique, (2) performing non-uniform Hilbert transform, and (3) applying the reorganized Novikov's formula. Numerical evaluations demonstrated its computational efficiency and sound stability to different levels of Poisson noise. It also seemed to be very robust to different settings of fan-beam geometry from very long to very short focal lengths without affecting the reconstruction accuracy.
Ultrastructure of Developing Feline Nonciliated Bronchiolar Epithelial Cells

Abstract The ultrastructure of the developing bronchiolar cell was studied in six age groups: prenatal (60 d post-conception); postnatal (1-, 7-, 14- and 21-day-old); and adult. Following intratracheal fixation, the lung tissue was processed for scanning and transmission electron microscopy. The lining of terminal bronchioles consists of cuboidal to columnar nonciliated bronchiolar cells (NBCs) and ciliated with or without microvilli. NBCs were recognized by indented centrally located nucleus. The apical surface extended beyond the surface of neighboring cells and was covered by minute microvilli, except in prenatal kittens. The NBCs of the adult were characterized by abundant mitochondria and glycogen inclusions. In prenatal kittens, the cytoplasm was filled with patches of alpha and beta form of glycogen. Postnatally, glycogen was reduced in quantity, became scattered throughout the cytoplasm and was predominantly of the beta form. Islands of cytoplasm, separated from the apical cytoplasm were observed in the lumen of adult bronchioles. This suggests an apocrine mode of secretion. The NBCs attain maturity by three weeks of age.