Miracle-dz/UniFAR-FTUs huggingface dataset:
Energy Efficient Resource Allocation in Heterogeneous Cloud Radio Access Networks

Energy harvesting is becoming an attractive option of energy supply for wireless networks as it can effectively reduce capital expenditure (CAPEX) and operational expenditure (OPEX). In this paper, an energy efficient radio resource optimization algorithm is proposed for a two-tier heterogeneous cloud radio access network (H-CRAN) where macro cells are empowered by conventional grid power and remote radio heads (RRH) are empowered by renewable energy sources. The resource allocation optimization is firstly formulated as a mixed integer programming problem, which is NP-hard. Therefore, an equivalent green power utilization maximization problem is formulated, and solved by Lagrange dual decomposition method. Numerical results show that the proposed algorithm can increase the utilization of the green power harvested from the renewable energy sources. This, in turn, leads to reduced grid power consumption compared to the baseline algorithms.
Structural Variety of Cobalt(II), Nickel(II), Zinc(II), and Cadmium(II) Complexes with 4,4'-Azopyridine: Synthesis, Structure and Luminescence Properties.

Self-assembled bi- and polymetallic complexes of Co(II), Ni(II), Zn(II), and Cd(II) were obtained by the reaction of 4,4'-azopyridine (azpy) with metal tri-tert-butoxysilanethiolates (Co, 1; Cd, 2), acetylacetonates (Ni, 3; Zn, 4), and acetates (Cd, 5). All compounds were characterized by single-crystal X-ray structure analysis, elemental analysis, FTIR spectroscopy, and thermogravimetry. Complexes 1, 2 and 4, 5 exhibit diverse structural conformations: 1 is bimetallic, 2 and 4 are 1D coordination polymers, and 5 is a 2D coordination framework formed from bimetallic units. The obtained complexes contain metal atoms bridged by a molecule of azpy. The luminescent properties of 1-5 were investigated in the solid state.
Perforated appendicitis in patients with schizophrenia: a retrospective cohort study

Objective Altered pain sensitivity may affect the outcome of appendicitis in patients with schizophrenia. We aimed to compare the prevalence of perforation in appendicitis between patients with and without schizophrenia. Design Retrospective cohort study with random matching. Setting A single tertiary medical centre in Japan. Participants From 1985 to 2013, 1821 cases of appendicitis requiring appendectomy were collected. Patients with schizophrenia and a cohort of randomly selected control subjects without schizophrenia who underwent appendectomy were identified. Primary and secondary outcome measures The primary outcome was the rate of perforated appendicitis in patients with and without schizophrenia. Secondary outcome was the odds of perforated appendicitis by different clinical factors. Results 62 patients with schizophrenia and randomly sampled 200 non-schizophrenic patients were compared. The prevalence of perforation was 53% in patients with schizophrenia versus 17% in controls (p<0.0001). The adjusted OR for perforation were 4.87 (95% CI: 2.33 to 10.2) for schizophrenia, 3.35 (95% CI 1.51 to 7.45) for age >55 years and 2.18 (95% CI: 1.12 to 4.27) for delayed presentation. Conclusion Appendiceal perforation was more frequent in patients with schizophrenia than controls, which may be partly attributable to delayed presentation and altered responses to pain.
Mammalian Sperm-Egg Fusion: Evidence That Epididymal Protein DE Plays a Role in Mouse Gamete Fusion1

Abstract Rat epididymal protein DE associates with the sperm surface during epididymal maturation and is a candidate molecule for mediating gamete membrane fusion in the rat. Here, we provide evidence supporting a role for DE in mouse sperm-egg fusion. Western blot studies indicated that the antibody against rat protein DE can recognize the mouse homologue in both epididymal tissue and sperm extracts. Indirect immunofluorescence studies using this antibody localized the protein on the dorsal region of the acrosome. Experiments in which zona-free mouse eggs were coincubated with mouse capacitated sperm in the presence of DE showed a significant and concentration-dependent inhibition in the percentage of penetrated eggs, with no effect on either the percentage of oocytes with bound sperm or the number of sperm bound per egg. Immunofluorescence experiments revealed specific DE-binding sites on the fusogenic region of mouse eggs. Because mouse sperm can penetrate zona-free rat eggs, the participation of DE in this interaction was also investigated. The presence of the protein during gamete coincubation produced a significant reduction in the percentage of penetrated eggs, without affecting the binding of sperm to the oolemma. These observations support the involvement of DE in an event subsequent to sperm-egg binding and leading to fusion in both homologous (mouse-mouse) and heterologous (mouse-rat) sperm-egg interaction. The lack of disintegrin domains in DE indicates that the protein interacts with its egg-binding sites through a novel mechanism that does not involve the reported disintegrin-integrin interaction.
Improved Neural Machine Translation with SMT Features

Neural machine translation (NMT) conducts end-to-end translation with a source language encoder and a target language decoder, making promising translation performance. However, as a newly emerged approach, the method has some limitations. An NMT system usually has to apply a vocabulary of certain size to avoid the time-consuming training and decoding, thus it causes a serious out-of-vocabulary problem. Furthermore, the decoder lacks a mechanism to guarantee all the source words to be translated and usually favors short translations, resulting in fluent but inadequate translations. In order to solve the above problems, we incorporate statistical machine translation (SMT) features, such as a translation model and an n-gram language model, with the NMT model under the log-linear framework. Our experiments show that the proposed method significantly improves the translation quality of the state-ofthe-art NMT system on Chinese-to-English translation tasks. Our method produces a gain of up to 2.33 BLEU score on NIST open test sets.
The use of mineral trioxide aggregate in one-visit apexification treatment: a prospective study.

AIM To assess the outcome of apexification using mineral trioxide aggregate (MTA). METHODOLOGY Fifty-seven teeth with open apices on 50 patients referred for root canal treatment received an apexification procedure in one appointment with MTA by the same operator. Patients were recalled at 6 months, 12 months and every year thereafter. Blind to the treatment record, two examiners assessed the pre-treatment, post-treatment and control radiographs of the study patients in a dark room using a magnifier. Each apex visible on the radiographs was scored with the periapical index (PAI), and the size of the apical lesion was measured. The presence of an apical bridge was also noted. Kappa-Cohen test was used for examiners calibration. The paired t-test was used for statistical analysis of apical healing. RESULTS Forty-three cases were included with at least 12 months follow-up. When considering the PAI score and the decrease in size of the apical lesion, healing occurred in 81% of cases. CONCLUSION Apexification in one step using an apical plug of MTA can be considered a predictable treatment, and may be an alternative to the use of calcium hydroxide.
Dielectric permittivity measurement methods of textile substrate of textile transmission lines

The article describes measurement methods of the dielectric permittivity which is the most important parameter of the substrate of new kind, textronic, transmission lines. The paper also presents the classification and short description of these methods and discusses their suitability for dielectric permittivity measurement of textile substrates. The substrate permittivity of the textile transmission line is one of electrical parameters which determines their suitability for the transmission of signals with a wide frequency spectrum. The paper discusses the main difficulties related to the dielectric permittivity measurement of flat textiles. The paper also presents examples of permittivity measurements of textile substrate line using selected method. Slowa kluczowe: Tekstronika, przenikalnośc dielektryczna, tekstylne linie transmisyjne, tekstylne linie sygnalowe
The High Mobility Group A1 (HMGA1) Transcriptome in Cancer and Development.

BACKGROUND & OBJECTIVES Chromatin structure is the single most important feature that distinguishes a cancer cell from a normal cell histologically. Chromatin remodeling proteins regulate chromatin structure and high mobility group A (HMGA1) proteins are among the most abundant, nonhistone chromatin remodeling proteins found in cancer cells. These proteins include HMGA1a/HMGA1b isoforms, which result from alternatively spliced mRNA. The HMGA1 gene is overexpressed in cancer and high levels portend a poor prognosis in diverse tumors. HMGA1 is also highly expressed during embryogenesis and postnatally in adult stem cells. Overexpression of HMGA1 drives neoplastic transformation in cultured cells, while inhibiting HMGA1 blocks oncogenic and cancer stem cell properties. Hmga1 transgenic mice succumb to aggressive tumors, demonstrating that dysregulated expression of HMGA1 causes cancer in vivo. HMGA1 is also required for reprogramming somatic cells into induced pluripotent stem cells. HMGA1 proteins function as ancillary transcription factors that bend chromatin and recruit other transcription factors to DNA. They induce oncogenic transformation by activating or repressing specific genes involved in this process and an HMGA1 "transcriptome" is emerging. Although prior studies reveal potent oncogenic properties of HMGA1, we are only beginning to understand the molecular mechanisms through which HMGA1 functions. In this review, we summarize the list of putative downstream transcriptional targets regulated by HMGA1. We also briefly discuss studies linking HMGA1 to Alzheimer's disease and type-2 diabetes. CONCLUSION Further elucidation of HMGA1 function should lead to novel therapeutic strategies for cancer and possibly for other diseases associated with aberrant HMGA1 expression.
Second pathway for completion of human DNA base excision‐repair: reconstitution with purified proteins and requirement for DNase IV (FEN1)

Two forms of DNA base excision‐repair (BER) have been observed: a ‘short‐patch’ BER pathway involving replacement of one nucleotide and a ‘long‐patch’ BER pathway with gap‐filling of several nucleotides. The latter mode of repair has been investigated using human cell‐free extracts or purified proteins. Correction of a regular abasic site in DNA mainly involves incorporation of a single nucleotide, whereas repair patches of two to six nucleotides in length were found after repair of a reduced or oxidized abasic site. Human AP endonuclease, DNA polymerase β and a DNA ligase (either III or I) were sufficient for the repair of a regular AP site. In contrast, the structure‐specific nuclease DNase IV (FEN1) was essential for repair of a reduced AP site, which occurred through the long‐patch BER pathway. DNase IV was required for cleavage of a reaction intermediate generated by template strand displacement during gap‐filling. XPG, a related nuclease, could not substitute for DNase IV. The long‐patch BER pathway was largely dependent on DNA polymerase β in cell extracts, but the reaction could be reconstituted with either DNA polymerase β or δ. Efficient repair of γ‐ray‐induced oxidized AP sites in plasmid DNA also required DNase IV. PCNA could promote the Pol β‐dependent long‐patch pathway by stimulation of DNase IV.
Development of the osteocranium in Corydoras aeneus (Gill, 1858) Callichthyidae, Siluriformes

Development in the osteocranium of Corydoras aeneus was studied based on 48 cleared and stained specimens and 10 series of serial sections. Development overall follows the general trends observed in siluriform development, with ossifications appearing as a response to functional demands. Early development of the skull occurs in two distinct phases. In a first phase, several new bony elements, all of dermal origin and related to feeding, appear shortly after yolk depletion (4.4 mm SL). Between 5 and 8 mm SL, developmental priorities seem to shift to size increase of the cartilaginous skull and no new bony elements appear. Finally, a second phase of osteogenesis occurs from 8 to 18 mm SL, in which all remaining dermal and perichondral bones appear. J. Morphol. 2011. © 2011 Wiley‐Liss, Inc.
The Future of Higher Education Teaching and the Student Experience

To do this will require a clearer sense of relative responsibilities. We will not be able to take the student experience forward unless we see it as a joint venture between students and those who provide higher education. Universities and colleges should be prepared to contemplate remodelling their curricula, perhaps radically, and building a more flexible workforce. Government and agencies should be ready to introduce funding models and quality systems that will realise a vision of higher education as an engaged partnership between students and providers.
Genetic dissection of plexin signaling in vivo

Significance Plexins, a family of transmembrane receptors for semaphorins, control diverse biological processes during mouse development. However, it is largely unknown through which signaling pathways they exert their functions in vivo. Using an allelic series of transgenic mice, we show that the GTPase activating protein domain of plexins constitutes their key signaling module during development, which is required for proper formation of the nervous, cardiovascular, and skeletal system. In contrast, development of the liver vasculature specifically depends on the activation of the small GTPase RhoA by the plexin family member Plexin-B2. This study uncovers the in vivo context-dependence and functional specificity of individual plexin-mediated signaling pathways during mouse development. Mammalian plexins constitute a family of transmembrane receptors for semaphorins and represent critical regulators of various processes during development of the nervous, cardiovascular, skeletal, and renal system. In vitro studies have shown that plexins exert their effects via an intracellular R-Ras/M-Ras GTPase-activating protein (GAP) domain or by activation of RhoA through interaction with Rho guanine nucleotide exchange factor proteins. However, which of these signaling pathways are relevant for plexin functions in vivo is largely unknown. Using an allelic series of transgenic mice, we show that the GAP domain of plexins constitutes their key signaling module during development. Mice in which endogenous Plexin-B2 or Plexin-D1 is replaced by transgenic versions harboring mutations in the GAP domain recapitulate the phenotypes of the respective null mutants in the developing nervous, vascular, and skeletal system. We further provide genetic evidence that, unexpectedly, the GAP domain-mediated developmental functions of plexins are not brought about via R-Ras and M-Ras inactivation. In contrast to the GAP domain mutants, Plexin-B2 transgenic mice defective in Rho guanine nucleotide exchange factor binding are viable and fertile but exhibit abnormal development of the liver vasculature. Our genetic analyses uncover the in vivo context-dependence and functional specificity of individual plexin-mediated signaling pathways during development.
Scale-Invariant Recognition by Weight-Shared CNNs in Parallel

Deep convolutional neural networks (CNNs) have become one of the most successful methods for image processing tasks in past few years. Recent studies on modern residual architectures, enabling CNNs to be much deeper, have achieved much better results thanks to their high expressive ability by numerous parameters. In general, CNNs are known to have the robustness to the small parallel shift of objects in images by their local receptive fields, weight parameters shared by each unit, and pooling layers sandwiching them. However, CNNs have a limited robustness to the other geometric transformations such as scaling and rotation, and this lack becomes an obstacle to performance improvement even now. This paper proposes a novel network architecture, the weight-shared multi-stage network (WSMS-Net), and focuses on acquiring the scale invariance by constructing of multiple stages of CNNs. The WSMS-Net is easily combined with existing deep CNNs, enables existing deep CNNs to acquire a robustness to the scaling, and therefore, achieves higher classification accuracy on CIFAR-10, CIFAR-100 and ImageNet datasets.
Induction of skin ulcers in moon light gourami (Trichogaster microlepis) with Aphanomyces invadans zoospores.

Epizootic ulcerative syndrome (EUS) is one of the seasonal and economically devastating diseases in the wild and farmed fresh water and estuarine fish. Thus, an experimental study was conducted by the Faculty of Veterinary Medicine, Universiti Putra Malaysia (UPM) from February to April 2012, to examine the susceptibility of Malaysia’s indigenous fish to EUS infection. In this experiment, forty apparently healthy moonlight gourami (Trichogaster microlepis) (10 ± 2 g body weight and 7.5 ± 1 cm in body length) were kept at 20 °C and challenged by intramuscular injection of zoospores (0.1 ml of 10,000 spores ml–1 suspension ) of Aphanomyces invadans (isolate NJM9701). Fish were observed daily for characteristic EUS clinical signs during the 14-day trial and sampled at 1, 2, 4, 6, 7, 8, 9, 10, 11, 13, 12, 14 days post-injection. The infected skin and muscle were then sampled for histopathological examination. The results demonstrated that injected fish started to develop lesions that were histopathologically and grossly identical to those found in naturally EUS-infected fish and they died within two weeks after the infection. The profoundly penetrating ulcers had characteristics such as severe dermatitis, myofibrillar degeneration, and deep necrotizing granulomatous myositis. Therefore, the result of this study proved that moonlight gourami was vulnerable to the EUS agent.
Nurses’ and Physicians’ Opinions on Aggressiveness of Treatment for General Ward Patients

The aim of this study was to evaluate agreement between nurses’ and physicians’ opinions regarding aggressiveness of treatment and to investigate and compare the rationales on which their opinions were based. Structured interviews regarding 714 patients were performed on seven general wards of a university hospital. The data gathered were then subjected to qualitative and quantitative analyses. There was 86% agreement between nurses’ and physicians’ opinions regarding full or limited treatment when the answers given as ‘uncertain’ were excluded. Agreement was less (77%) for patients with a life expectancy of less than one year. Disagreements were not associated with professional status because the physicians considered limiting life-sustaining treatment as often as the nurses. A broad spectrum of rationales was given but the results focus mostly on those for full treatment. The nurses and the physicians had similar bases for their opinions. For the majority of the patients, medical rationales were used, but age and quality of life were also expressed as important determinants. When considering full treatment, nurses used quality-of-life rationales for significantly more patients than the physicians. Respect for patients’ wishes had a minor influence.
Phenotypic and Genomic Variation among Staphylococcus epidermidis Strains Infecting Joint Prostheses

ABSTRACT We studied the SmaI and SstII macrorestriction patterns of 54 Staphylococcus epidermidisstrains isolated from 14 patients infected following the implantation of joint prostheses. Multiple strains from pus and infected tissue specimens of each patient were selected on the basis of different colony morphologies and drug resistance patterns. The same criteria were used to select 23 S. epidermidis strains from hand swabs of eight healthy individuals. For 10 of the 14 patients, all the intrapatient strains appeared to be closely or possibly related, whereas related strains were detected in the skin flora of only one of the eight healthy individuals. This observation suggests that, in most cases, the patients were infected by a single S. epidermidis clone which subsequently underwent rearrangements that yielded derivatives with divergent phenotypes and, occasionally, divergent macrorestriction patterns. The four patients whose specimens contained unrelated S. epidermidisstrains were probably infected with several polyclonal strains.
Initial use of a broth microdilution method suitable for in vitro testing of fungal isolates in a clinical microbiology laboratory

Antifungal susceptibility testing methods currently lack a standardized procedure. Many factors, such as inoculum preparation, inoculum density, medium selection, pH, incubation time and temperature, and endpoint determination, affect results. We developed a workable procedure for fungal susceptibility testing, with a microtiter method based upon modifications of the proposed guidelines from the National Committee for Clinical Laboratory Standards, using two different growth media. For this procedure, the microtiter tray is prepared as a panel of 6 drugs (amphotericin B, flucytosine, fluconazole, ketoconazole, miconazole, and itraconazole) alone and in combination with amphotericin B. Eagle's minimal essential medium and RPMI 1640 are the two growth media. Two separate susceptibility trays are inoculated for each sensitivity test, with one tray incubated at 30 degrees C and the other incubated at 35 degrees C. After 48 h of growth, results for both temperatures and both media are recorded and interpreted. The four test environments (two media each at two temperatures) provided growth for 100 of the first 104 organisms that were submitted for testing. This approach provides a workable methodology for routine antifungal susceptibility testing in a clinical microbiology laboratory setting.
Thoracoabdominal breathing motion pattern and coordination of professional ballet dancers

Abstract Ballet training includes exercises of high and moderate intensities, which require breathing control for a good performance. This study describes the thoracoabdominal motion of professional dancers and compares the breathing patterns between professional dancers and non-dancers. Participants of this study were four male and four female (30.33 ± 4.64 years) professional dancers and four male and four female (22.75 ± 1.49 years) non-dancers. The participants executed two breathing manoeuvres while sitting motionless: quiet breathing (QB) and vital capacity (VC). The 3D coordinates of 32 retro-reflective markers positioned on the trunk were used to calculate the volume of the superior thorax, inferior thorax and abdomen. Principal component analysis was applied in the volume variation of each trunk compartment to search for dominant independent variables in a breathing motion pattern. The correlation coefficient was calculated to verify the coordination between the compartments during the breathing manoeuvres. A predominance of the superior thorax or abdomen movement was found in both groups. The professional ballet dancers have an efficient breathing pattern and maintain the same breathing pattern in QB and VC manoeuvres. On the other hand, the non-dancers group showed relevant changes of the breathing pattern to respond to a greater breathing effort, like in VC.