Miracle-dz/UniFAR-FTUs huggingface dataset:
Leukokinetic studies. III. The distribution of granulocytes in the blood of normal subjects.

In a previous publication (1) it was noted that when granulocytes were labeled in vitro with radioactive diisopropylfluorophosphate (DFP32 ) and then returned to the circulation of the donor, about half of the labeled cells could not be found in the circulation at the completion of the infusion (T0). Thereafter the remaining labeled cells left the circulation in a random fashion with a mean halftime disappearance (T.) of 6.6 hours. Since cell damage and significant elution of the label could not be demonstrated tinder the conditions of the study, it was suggested that the immediate disappearance of half the infused cells was due to their rapid dilution in a larger pool than that calculated from the blood volume and the venous granulocyte count. The concept that the circulating granulocyte pool (CGP) does not constitute all of the intravascular leukocytes is not new. Vejlenis (2) reviewed the lntumerotus inivestigations carried out up to 1938 and pointed out that as early as 1867 Cohnheim observed white cells in a marginal position along the walls of venutles. By microscopic examination it has since been demonstrated that leukocytes may circulate freely in the blood, adhere to the vascular enidothelium in sites where the blood flow is relatively slow and then once again re-enter the circulation in a process of continuous exchange (2). If DFP32-labeled granulocytes come into rapid equilibrium with marginated granulocytes, it might be expected that one could account for most if not all of the labeled cells bv mobilizing the marginated cells into the circulation Nwith epinephrine. M\Io-
MEASURING THE CORONAL PROPERTIES OF IC 4329A WITH NuSTAR

We present an analysis of a ∼160 ks NuSTAR observation of the nearby bright Seyfert galaxy IC 4329A. The high-quality broadband spectrum enables us to separate the effects of distant reflection from the direct coronal continuum, and to therefore accurately measure the high-energy cutoff to be . The coronal emission arises from accretion disk photons Compton up-scattered by a thermal plasma, with the spectral index and cutoff being due to a combination of the finite plasma temperature and optical depth. Applying standard Comptonization models, we measure both physical properties independently using the best signal to noise obtained to date in an active galactic nucleus over the 3–79 keV band. We derive with assuming a slab geometry for the plasma, and with for a spherical geometry, with both having an equivalent goodness-of-fit.
Improving the process for public transport patronage forecasting

Public transport demand forecasting is a challenging and controversial process and both Australian and international forecasts have frequently been criticised for overestimating likely demand. It is important that organisations managing these forecasts develop sound processes to provide assurance to senior management, boards and key external stakeholders that the risks of inaccurate or inappropriate forecasts are being properly managed. In this paper, our goal was to develop recommendations for modelling practitioners and clients at both a strategic and project level to assist in the management of forecasting risks. To reach this goal the authors undertook a risk assessment of the patronage forecasting process for public transport considering: 1. the key stakeholders; 2. the objectives of a good public transport forecast; 3. the risks to achieving these objectives; and 4. management of these risks. Our methodology involved a literature review and in-depth discussions with 17 stakeholders in the NSW forecasting environment. (a) For the covering entry of this conference, please see ITRD abstract no. E213716.
Phosphorylation of the Inositol 1,4,5-Trisphosphate Receptor

The effects of cyclic GMP (cGMP) and activation of cGMP-dependent protein kinase (PKG) on the phosphorylation of the inositol 1,4,5-trisphosphate (IP3) receptor were examined in intact rat aorta using the technique of back phosphorylation. Aorta treated with the nitric oxide donors, S-nitroso-N-acetylpenicillamine and sodium nitroprusside, or the selective PKG activator, 8-(4-para-chlorophenylthio)-cGMP (8-CPT-cGMP), demonstrated increased IP3 receptor phosphorylation in situ, which was both time- and concentration-dependent with a stoichiometry of 0.5 mol of phosphate/mol of receptor above control. Treatment of aorta with the adenyl cyclase activator, forskolin, also demonstrated increased phosphorylation of the IP3 receptor on the PKG site, although the selective cAMP-dependent protein kinase activator, 8-(4-para-chlorophenylthio)-cAMP (8-CPT-cAMP), did not increase the phosphorylation of the IP3 receptor. Moreover, the PKG selective inhibitor, KT 5823, inhibited both sodium nitroprusside and forskolin-induced IP3 receptor phosphorylation more potently than the selective cAMP-dependent protein kinase inhibitor, KT 5720, suggesting that PKG mediates the increase in IP3 receptor phosphorylation by both cyclic nucleotides in intact aorta. These results provide further support for the notion that PKG is activated by both cAMP and cGMP in intact vascular smooth muscle and that PKG performs a critical role in cyclic nucleotide-dependent relaxation of blood vessels.
Granular flow down an inclined plane: Bagnold scaling and rheology.

We have performed a systematic, large-scale simulation study of granular media in two and three dimensions, investigating the rheology of cohesionless granular particles in inclined plane geometries, i.e., chute flows. We find that over a wide range of parameter space of interaction coefficients and inclination angles, a steady-state flow regime exists in which the energy input from gravity balances that dissipated from friction and inelastic collisions. In this regime, the bulk packing fraction (away from the top free surface and the bottom plate boundary) remains constant as a function of depth z, of the pile. The velocity profile in the direction of flow vx(z) scales with height of the pile H, according to vx(z) proportional to H(alpha), with alpha=1.52+/-0.05. However, the behavior of the normal stresses indicates that existing simple theories of granular flow do not capture all of the features evidenced in the simulations.
Analysis of Depth Perception with Virtual Mask in Stereoscopic AR

A practical application of Augmented Reality (AR) is see-through vision, a technique that enables a user to observe an inner object located behind a real object by superimposing the virtually visualized inner object onto the real object surface (for example, pipes and cables behind a wall or under a floor). A challenge in such applications is to provide proper depth perception when an inner virtual object image is overlaid on a real object. To improve depth perception in stereoscopic AR, we propose a method that overlays a random-dot mask on the real object surface. This method conveys to the observers the illusion of observing the virtual object through many small holes. We named this perception "stereoscopic pseudo-transparency. " Our experiments investigated (1) the effectiveness of the proposed method in improving the depth perception between the real object surface and the virtual object compared to existing methods, and (2) whether the proposed method can be used in an actual AR environment.
Reallocation of road space

This research project investigated the economic impacts of transport and road space reallocation in shopping areas located in central cities and along major transport corridors in New Zealand. It focused on three research questions. The first being to understand the retail spending of transport users; resulting in data that provides an average dollar spent per user and primary mode of transport. The second element focused on identifying the road space allocation and design elements important to retailers and shoppers. Finally, a case study compendium was developed. The data shows that sustainable transport users account for 40 per cent of the total spend in the shopping areas and account for 37 per cent of all shoppers who completed the survey. The data indicates the pedestrians and cyclists contribute a higher economic spend proportionately to the modal share and are important to the economic viability of local shopping areas. The study also identified that retailers generally overestimate the importance of on-street parking outside shops. Shoppers value high-quality pedestrian and urban design features in shopping areas more than they value parking and those who drive are willing to walk to the shopping precinct from other locally available parking areas.
pulp and paper industry

ABSTRACT Uniformity of physical properties of paper continues to be one of the most serious quality issues in today's paper mills. Thelarge-scale "average" profile can often be controlled effectively with today' s technologies. However, to detect and controlsizes from several microns to a few centimeters remains the industry's biggest challenge. Over the last several years, INO hasdeveloped and perfected an entirely new instrument to measure surface fiber orientation. This non-destructive, non-contacttechnique can more appropriately be described as a surface strain tester. It is slowly finding its way in various laboratoriesaround the world, notably Sweden, United States and France. The instrument uses a custom designed phase-modulated, laser-based ellipsometer in the far infrared spectral region. It basically measures the local surface birefringence and direction of theoptic axis. Our approach is highly unusual since it works for samples of widely varying surface roughness and does notrequire careful alignment of the sample with respect to the laser beam. This paper describes how the instrument works, whatit measures and illustrates various applications from small scale mapping to cross-machine profiles.
STUDY ON THE FINGERPRINT PATTERN AND GENDER DISTRIBUTION IN AND AROUND NANDED DISTRICT OF MAHARASHTRA STATE

Identification of a person can be broadly classified into two categories, viz., complete and partial identification [1]. Although the complete identification of an individual is a responsibility of police officers and is the ultimate goal, most of the time it gets difficult especially in mutilated and intensely decomposed bodies. In such cases, the partial identification done by a forensic expert or medical officers becomes equally important to arrive at a certain conclusion and may also lead to the complete determination of individuality of a person [2].
Social Media Measurement

Social media measurement is quite immature, just as Web analytics was back in the mid-1990s. It will evolve quickly as marketers attempt different approaches and hold enterprise measurement firms accountable to help make sense of all the activity data generated by social media interactions. In turn, social media can seem very challenging, and at times even impossible, to measure with regard to its effects. At its core, digital measurement is contingent on controlling the customer experience and laying tracking hooks along the way to understand response and subsequent behavior. However, social media's foundation challenges this very tenet: The consumer is now in control after all!
Effect of estradiol versus estradiol and testosterone on brain-activation patterns in postmenopausal women

Objective: To determine the effect of estradiol and testosterone on brain-activation patterns in surgically postmenopausal women viewing erotic video clips using functional magnetic resonance imaging. Design: Six women, who had undergone a bilateral oophorectomy and hysterectomy for benign disease, viewed erotic and neutral videos during functional magnetic resonance imaging while not on hormone therapy, while on estradiol therapy, and while on estradiol and testosterone therapy. Five similarly aged premenopausal women viewed the same videos. Areas of brain activation between the functional magnetic resonance imaging scans of both groups of women were compared with determine whether agonadal serum levels of sex hormones and administration of estradiol and testosterone impacted brain patterns of sexual arousal. Results: When compared with premenopausal women, untreated postmenopausal women had significantly decreased areas of brain activation during both erotic and neutral stimulations. Administration of estradiol increased global brain-activation patterns during both visual stimulations, with erotic video viewing causing a limited increase in limbic system activation. Combined estradiol and testosterone therapy was associated with a greater activation of the central nervous system, with more limbic system activated during the erotic video. Brain-activation patterns of the postmenopausal women were similar to the premenopausal group only during the estradiol and testosterone treatment phase. Conclusions: Agonadal serum hormone levels result in globally decreased brain-activation patterns in postmenopausal women while viewing neutral and erotic videos. Administration of both estradiol and testosterone increase global brain activation, and both sex steroids are independently associated with enhanced limbic system response during erotic visual stimulation.
TAX STRUCTURE AND THE LOCATION OF ECONOMIC ACTIVITY ALONG STATE BORDERS

This paper documents research on the effect that differential tax structures have in distorting the location of retail sales and employment along state borders. Increases in the state and local sales tax rate are found to reduce the level of retail activity on that side of the state border for two of the three moderately sized metropolitan areas which are studied. Employment and sales exhibited approximately the same responsiveness to tax rate changes. State income taxes are found to have minor influences on the location of retail activity and increases in selective sales tax rates generally create zero or very small effects on overall retail activity. The results indicate that consumers are more likely to change their consumption behavior in response to increases in the easily observable general sales tax than in other taxes that may indirectly raise business costs.
Pesticide intoxications in Cukurova, Turkey: three years analysis

In Cukurova region, pesticide poisonings still remain an unfortunate cause of death, which led to the present study. The autopsy records of Adana Branch of the Council of Forensic Medicine, between 2006 and 2008, were evaluated retrospectively. Deaths that were attributed to pesticide poisoning were included in the scope of the study to identify the type of pesticide, and etiology of intoxication. The frequency and distribution of intoxications were also analyzed in terms of sex and age. In the studied period, a total of 4199 autopsies were referred to the forensic toxicology laboratory for pesticide analysis. Seventy-two cases were positive for pesticide analysis. Of these, 42 (58.33%) were male and 30 (41.67%) were female, with a mean age of 38.8 ± 20.6 years. Among the inspected pesticides, endosulfan was found to be the most common with 47.2% of prevalence, followed by dichlorvos. This report showed that certain pesticides, endosulfan in particular, remains as common cause of poisonings in Cukurova region.
Managerial Labor Market Frictions and Corporate Investment

We argue that corporate investment decisions depend not only on project characteristics such as expected NPV, but also on how well a firm can assess its managers’ human capital. If so, projects pitched by managers about whom the firm has more complete information should be more likely to be funded, all else equal. Using a novel matched employer-employee dataset of firms in the U.S. venture capital (VC) industry and exploiting employees’ moves across VC firms for identification, we show that external hires experience a dip in investment activity when they join a new VC firm. Over time, the gap between external hires and seasoned insiders closes, consistent with the firm gathering information about managerial ability. Exogenous shocks to a firm’s ability to learn result in a slower rate of convergence between external hires and insiders. The data are best explained by the interpretation that informational frictions in the managerial labor market have a significant impact on investment policy.
Treatment of Hypertension in Patients With Coronary Artery Disease: A Scientific Statement From the American Heart Association, American College of Cardiology, and American Society of Hypertension

1. Relationship Between Hypertension and CAD 1374 2. Prevention of Cardiovascular Events in Patients With Hypertension and CAD 1380 3. BP Goals 1382 4. Management of Hypertension in Patients With CAD and Stable Angina 1386 5. Management of Hypertension in Patients With ACS 1388
Adaptive task-space synchronisation of networked robotic agents without task-space velocity measurements

In this paper, we investigate the problem of task-space synchronisation of multiple robotic agents in the presence of uncertain kinematics and dynamics. Our control objective is to realise synchronisation without the measurements of task-space velocity. The communication topology is assumed to be directed graphs containing a spanning tree. A decentralised task-space observer with kinematic parameter updating is proposed to avoid the reliance of task-space velocity. Based on the observer, we propose the distributed adaptive synchronisation controller for two cases: (1) the leaderless consensus case and (2) the leader-follower case, where all the followers track the convex hull spanned by the virtual leaders and for each follower, it is required that there exists at least one leader that has a directed path to the follower. The asymptotic synchronisation is proved with Lyapunov analysis and input–output stability analysis tools. Simulations with multiple robotic agents are performed to show the effectiveness of the proposed schemes.
Identification and control of 2DOF nonlinear helicopter model using intelligent methods

This paper presents an implementation of soft computing methodologies, like genetic algorithm and fuzzy logic, in identification and control of 2DOF nonlinear helicopter model (Humusoft CE 150). The genetic algorithm is proposed for identification of the physical structure of helicopter system, which contains a helicopter body, main and tail motors and drivers. The quality of helicopter model achieved was validated through simulation and experimental modes. Then, this model is used to elevation and azimuth fuzzy logic Mamdani type controllers design in a simulation mode. The main objective of the paper is to obtain robust and stable controls for wide range of azimuth and elevation angles changing during the long time flight. The robustness and effectiveness of both fuzzy controllers were verified through both simulations and experiments.
Body composition in patients with inflammatory bowel disease: a population-based study

OBJECTIVES:Weight loss and nutritional depletion are common features of inflammatory bowel disease. Our aim was to assess body composition in patients with Crohn's disease (CD) and ulcerative colitis (UC) and to evaluate possible differences between the patient groups and healthy subjects.METHODS:A total of 60 patients with CD, 60 patients with UC, and 60 healthy subjects were investigated. Each group consisted of 24 men and 36 women. Body composition was measured by dual x-ray absorptiometry and Z scores were obtained by comparison to age- and sex-matched normal values.RESULTS:Bone mineral content and lean body mass were significantly lower in patients with CD compared with patients with UC and healthy subjects. The body composition of CD men was more strongly affected than that of women. UC patients had significantly higher fat mass and body mass index than patients with CD and healthy subjects. There was no difference in the percentage of fat mass between the two patient groups. Corticosteroid treatment and smoking had a negative impact on bone mineral content and lean body mass in CD patients independently of each other.CONCLUSIONS:CD was associated with disturbances in body composition: both bone mineral content and lean body mass were significantly reduced, especially in men with CD. Corticosteroid therapy and smoking had a significant influence on body composition in patients with CD. When studying the effects of inflammatory bowel disease on body composition and nutritional status, patients with CD and UC should be evaluated separately.
Tax Compliance Costs in New Zealand: An International Comparative Evaluation

The focus of this article is on the burden imposed by all aspects of compliance with tax obligations in New Zealand (NZ). It explores the levels of research into tax compliance costs undertaken in NZ and the outcomes of that research, and compares this data with comparable international experience. It establishes that NZ has a sound track record of research into tax compliance costs, at least at the government level, and certainly so far as research into business tax compliance costs is concerned. The outcomes of that research also suggest that NZ compares favourably with many other developed countries including its OECD counterparts in terms of the compliance cost burden faced by business and non-business taxpayers.
Characteristics and implications of attrition in health-related quality of life studies in palliative care

In a longitudinal study of 297 palliative care patients, 280 patients were followed from inclusion to death. Characteristics and health-related quality of life (HRQL) of the participants and those who later dropped out were compared at inclusion, and 3 and 2 months before their death. At inclusion, the dropouts were older (P = 0.001), had reduced Karnofsky performance score (P < 0.001), received more help from the local authority (P = 0.004) and had reduced HRQL compared with patients who continued in the study and completed the next questionnaire. There were no differences in any of the HRQL parameters between participants and dropouts 3 months before death. Two months before death, differences in HRQL were found, but in favour of the dropouts. Data from patients close to death may be representative of a larger group of patients, whereas initial dropouts may lead to a positive bias of reported HRQL.
Risk factors for HIV in pregnant women

Worldwide, the number of childbearing women infected with the human immunodeficiency virus HIV is rising. Early intervention can improve care for these women and reduce HIV transmission to their children. However, for intervention strategies to be effective, childbearing women at risk must be identified. HIV prevalence and risk factors vary widely from one region to another, and strategies for HIV testing must be tailored to local conditions. In this review, published data on HIV risk factors in pregnant women are presented by region, and implications for regional strategies for HIV testing in pregnant women are discussed.