Miracle-dz/UniFAR-FTUs huggingface dataset:
Advances in the understanding of the hydraulic behavior of wedge-shape block spillways

The technology of wedge shaped blocks (WSB) for spillways has had a rising development through the last forty years, and has proved its reliability for practical applications with spillways executed during the last decade. Ongoing additional research aims to complete the understanding of the hydraulic behavior, improve current design criteria and make this technology available to practitioners, in order to consider this type of spillway together with the conventional alternatives when designing an embankment dam spillway. A summary is here shown of recent research performed by the consortium formed by the research organizations: Research Group in Dam Safety (SERPA) of the Technical University of Madrid (UPM) and the International Center for Numerical Methods in Engineering (CIMNE) and the company PREHORQUISA. Even though the experimental campaign has not been completed, some preliminary conclusions can be addressed about the developed pressures along the block tread and the leakage flow from the joints among blocks and the drainage holes.
Do public investment and FDI crowd in or crowd out private domestic investment in Malaysia?

Motivated by the concern of a persistent decline in total investment in Malaysia during the post-crisis era, this article examines the long-run relationship between private domestic investment (PDI), public investment and foreign direct investment (FDI) in Malaysia. Using multivariate cointegration techniques, the results indicate a fairly robust cointegrated relationship between these variables during the period 1960 to 2003. Both public investment and FDI are found to be complementary to, rather than competing with, PDI.
Assessment of the Quality of Life in Korean Hemophiliacs: Impact of Disease-Related Factors, Social Status and Treatment Factors on the Quality of Life of Korean Hemophiliacs

The morbidity and mortality of hemophiliac patients has markedly decreased since the introduction of viral inactivation technologies, gene recombinant products, and prophylactic treatment. The success in the treatment of hemophilia requires a shift from the narrow focus on morbidity and mortality to the enhancement of quality of life and well being of patients. Therefore, health related quality of life (HRQoL) has been increasingly used as an outcome parameter in hemophilia treatment. Most of the quality of life (QoL) assessments for hemophiliac patients have mainly focused on the impact of the disease-related factors such as the severity of disease, inhibitor presence, arthropathy and human immunodeficiency virus (HIV) infection status of the patients. However, the QoL may differ depending on the social status of the patients. Epidemiologic and clinical research studies have indicated that social and cultural factors exert an influence on patients’ QoL, and the impact of these factors may differ among countries. Despite the plausible impact of social status on the QoL of hemophiliac patients, few researchers have studied the impact of social status such as marital status and occupational status on the QoL of hemophiliac patients. Furthermore, it is important to identify factors affecting the QoL of hemophiliac patients, such as social status and treatment, in order to establish potential intervention strategies across different countries. Therefore, the impact of social status, disease-related factors and treatment factors on the QoL were evaluated in Korean hemophiliac patients.
A global analysis of the seaward salt marsh extent: The importance of tidal range

Despite the growing interest in ecosystem services provided by intertidal wetlands, we lack sufficient understanding of the processes that determine the seaward extent of salt marsh vegetation on tidal flats. With the present study, we aim to establish a globally valid demarcation between tidal flats and salt marsh vegetation in relation to tidal range. By comparing results from a regional GIS study with a global literature search on the salt marsh‐tidal flat border, we are able to define the global critical elevation, above which salt marsh plants can grow in the intertidal zone. Moreover, we calculate inundation characteristics from global tide gauge records to determine inundation duration and frequency at this predicted salt marsh‐tidal flat border depending on tidal range. Our study shows that the height difference between the lowest elevation of salt marsh pioneer vegetation and mean high water increases logarithmically with tidal range when including macrotidal salt marshes. Hence, the potentially vegetated section of the tidal frame below mean high water does not proportionally increase with tidal range. The data analysis suggests that inundation frequency rather than duration defines the global lower elevational limit of vascular salt marsh plants on tidal flats. This is critical information to better estimate sea level rise and coastal change effects on lateral marsh development.
Computational Insights into the Role of the Frontiers Orbital in the Chemistry of Tridentate Ligands

The FERM O concept emerges as a powerful and innovative implement to investigate the role of molecular orbitals applied in the description of breakage and formation of chemical bonds. In this work, Hartree-Fock (HF) and Density Functional Theory (DFT) calculations were carried out for a series of four tridentate ligands and their behavior was analyzed using molecular orb ital (M O) energies. It was observed that HOMO energies are inadequate to describe the Pearsons Hard and Solf acid-base (HSA B) p ricinple behavior of these compounds. By using the frontier effective-for-reaction molecular orbital (FERM O) concept, the reactions that are driven by HOM O, and those that are not, can be better exp lained, independent of the calculation method used, since both HF and Kohn-Sham methodologies lead to the same FERM O.
Characteristics of School Examination Test of Biology Subject

The results of the analysis of a test is indispensable for making the policies that should be done by a teacher in improving the quality of teaching and learning. This study aimed to describe characteristics of the school examination for Biology subject in Banjar Regency in the year of 2014/2015. The quantitative analysis was based on modern test theory using software version MICROCAT Big steps 2.30 on the response of the students' answers to the tests made in the Department of Education and Ministry of Religious Affairs. The results showed that the tests made in the Ministry of Religion have suitability items with the model of Rasch and better quality than the tests made in the Department of Education. Both tests had a level of difficulty that was good, discriminating power which was unacceptable, and the distribution of response answers that was not good. Statistics showed that the reliability of items was preferential while the reliability of persons was weak. Moreover, it was still found the students who responded inconsistently. Keywords—Biology, Characteristic, Examination
Work–life interferences in the early stages of academic careers: The case of precarious researchers in Italy

This paper addresses the topic of work–life interferences in academic contexts. More specifically, it focuses on early career researchers in the Italian university system. The total availability required from those who work in the research sector is leading to significant transformations of the temporalities of work, especially among the new generation of researchers, whose condition is characterized by a higher degree of instability and uncertainty. Which are the experiences of the early career researchers in an academic context constituted by a growing competition for permanent positions and, as a consequence, by a greatly increased pressure? Which are the main gender differences? In what elements do Science, Technology, Engineering and Mathematics disciplines differ from Social Sciences and Humanities? The collected narratives reveal how the ongoing process of precarization is affecting both the everyday working activities and the private and family lives of early career researchers, with important consequences also on their future prospects.
The Role of Policy Rules in Inflation Targeting

This paper seeks to clarify the ways in which inflation targeting corresponds to a policy rule conceptually, and to assess the extent to which inflation targeters' policy can be described by policy rules in practice. Using central banks' inflation and output forecasts, the empirical analysis shows that simple forward-looking instrument rules provide a reasonably good characterization of interest rate setting by the inflation-targeting Reserve Bank of New Zealand and Sveriges Riksbank, as well as by the U.S. Federal Reserve. While explicit inflation targeters tend to react more strongly to their inflation forecasts than the Fed, none is an inflation nutter, and all appear to exercise a large degree of judgment in setting policy. Simple optimal targeting rules appear generally less informative than empirical instrument rules.
Local-scale faunal turnover on the deep Pacific seafloor

The high biodiversity of the deep-sea floor is often attributed to high local coexistence of species achieved through microhabitat variation. Grassle & Sanders (1973; Deep-Sea Res 34: 313-341) proposed that deep-sea species were differentially adapted to multiple and small-scale suc- cessional patches that varied across the landscape and through time. However, results from both manipulative experiments and precision sampling to test the patch-mosaic model of Grassle & Sanders (1973) have varied, leading some authors to suggest that patch dynamics may be unimpor- tant in explaining deep-sea biodiversity. We utilized a remotely operated vehicle and a rigid spatial sampling protocol to document macrofaunal turnover and individual species spatial dispersion at a 3203 m deep site in the Pacific Ocean over scales of 1 to 350 m. We found high variability in assem- blage composition and, in contrast to most previous work, we also found that intraspecific species aggregation was common. These findings suggest that patch dynamics and microhabitat variation are important in promoting local species coexistence in the deep-sea benthos.
Comparative genomics by targeted capture and long read sequencing reveal dynamic evolution of hemoglobin gene clusters in codfishes

Teleost fishes is an extremely species rich group of vertebrates, showing a remarkable ability to adapt to a variety of aquatic environments. The fishes within this group display a wide diversity of hemoglobin variants, which is most likely linked to the array of different environments they inhabit and by such, acts as signatures of genetic adaptation. A main environmental factor – and a strong selective force – is temperature, as temperature directly influences the ability of teleost hemoglobin to bind oxygen at respiratory surfaces and its subsequently release in tissues. The overall goal of this study was to investigate the genetic basis of the evolution within the Hb gene clusters in Gadiformes – the codfishes – an order displaying a wide range of adaptations to temperature and depth. To do so, I determined the organization and synteny of the hemoglobin gene region in a selection of species of codfishes by targeted sequence capture using Pacific Biosciences long-read sequencing. Targeted capture technology involves the use of DNA probes to capture the genetic region of study. I here demonstrate successful targeted sequence capture and enrichment with custom made probes largely designed based on a published reference genome of the Atlantic cod for eight species of codfishes, with the most distant species sharing a most recent common ancestor with the Atlantic cod 70 million years ago. I present the syntenic relationship amongst Hb genes in six species – Atlantic cod, haddock, silvery cod, cusk, burbot and European hake. Interestingly, the sequenced data revealed that an indel suggested to be associated with thermal adaption in Atlantic cod populations, is present in the bidirectional promoter region of the Hb genes and in haddock, silvery cod and cusk. Overall, this study sheds light on the evolutionary history of the Hb clusters by revealing an overall conservation of genetic structure and synteny, but also lineage specific gene duplications, as well as variation in regulatory regions between genes.
A CROSS‐CULTURAL EXPLORATORY STUDY OF THE LINKAGE BETWEEN EMOTIONAL INTELLIGENCE AND MANAGERIAL EFFECTIVENESS

Multinationals increasingly require a cadre of skilled managers to effectively run their global operations. This exploratory study examines the relationship between emotional intelligence (EI) and managerial effectiveness among three cultures. EI is conceptualized and measured as self‐other agreement concerning the use of managerial skills using data gathered under a 360‐degree feedback process. Three hypotheses relating to managerial self‐awareness of both interactive and controlling skills are examined using data from 3,785 managers of a multinational firm located in the United States (US), United Kingdom (UK), and Malaysia. The two sets of managerial skills examined were found to be stable across the three national samples. The hypotheses were tested using polynomial regressions, and contour plots were developed to aid interpretation. Support was found for positive relationships between effectiveness and EI (self‐awareness). This relationship was supported for interactive skills in the US and UK samples and for controlling skills in the Malaysian and UK samples. Self‐awareness of different managerial skills varied by culture. It appears that in low power distance (PD) cultures such as the United States and United Kingdom, self‐awareness of interactive skills may be crucial relative to effectiveness whereas in high PD cultures, such as Malaysia self‐awareness of controlling skills may be crucial relative to effectiveness. These findings are discussed along with the implications for future research.
rAPD analysis of somaclonal variation in banana (Musa acuminate l.) cultivar Valery

Thirty decamer RAPD primers were used to study somaclonal variation among the parental plants as well as regenerated plants of the first, third, fifth, seventh and ninth sub-cultures. Eighteen out of thirty primers produced 289 bands in all the genotypes studied. Hundred and forty-two bands (48.95%) were common in the parental genotype and the re- generated plants while 147 bands were polymorph (51.40%). Among the primers used, OPI-07 produced the highest number of bands (24) while primers OPH-16 produced the lowest number (5). In total 74 specific bands were observed in the parental genotype and the regenerated plants of the sub-cultures. The presence of specific band/loci in the parental plants and loss of it in the regenerated plants of different sub-cultures indicates the loss of certain loci during tissue culture due to somaclonal variation. Such specific loci are of high importance in the genetic identification of the genotypes or somaclones from each other. Grouping of the parental cultivar and their sub-cultures regenerated plants indicate the genetic distinctness of the genotypes studied as they are placed in different clusters/groups far from each other. It also seems that the genetic variations induced in the regenerated plants increase with the time-period of the sub-culture. Acta Biol Szeged 52(2):307-311 (2008)
/ ReVISIón ASSeSSMenT OF ROTATIOn CROPS AnD COVeR CROPS FOR MAnAGeMenT OF ROOT-KnOT neMATODeS ( MELOIDOGYNE SPP . ) In THe SOUTHeASTeRn UnITeD STATeS

McSorley, R. , 2011. Assessment of rotation crops and cover crops for management of root-knot nematodes (Meloidogyne spp.) in the southeastern United States. Nematropica 41:200-214. Studies that utilized rotation crops for management of root-knot nematodes in the southeastern United States were examined to evaluate the overall performance of rotation crops. In general, nematode-susceptible crops that followed effective rotation crops produced yields and supported nematode numbers similar to those obtained on crops treated with most standard nematicides. Fumigation with methyl bromide was an exception, and resulted in low nematode numbers up to the end of the susceptible target crop, whereas nematode numbers recovered following rotation crops. Performance of rotation crops was similar to clean fallow in most studies, and there was little evidence that rotation crops could suppress nematode numbers below levels obtained after clean fallow. Large reductions in nematode numbers often were achieved following rotation crops. In sites with relatively low initial population levels before rotation crops were used, effective rotation crops sometimes maintained relatively low nematode numbers through the following susceptible target crop, and nematode recovery was not observed until the second year of the rotation sequences. Where practical, very long rotations such as bahiagrass pastures were often effective in preventing increase in nematode numbers on subsequent susceptible crops. Rehabilitation of heavily infested sites is difficult, could require several years of rotation crops, and the benefit gained may last only through one susceptible crop.
Preservation of Cardiac Function and Attenuation of Remodelling in Transient Receptor Potential Vanilloid 4 Knockout Mice Following Myocardial Infarctionnd Medical Center

Transient receptor potential channel vanilloid 4 (TRPV4) is a non-selective Ca2+ permeable cation channel, recently implicated by computational methods as a key signalling component during myocardial infarction. We previously showed that pharmacological TRPV4 inhibition can prevent and resolve pulmonary edema in pre-clinical heart failure animal models. Here, we examined the impact of genetic deletion of TRPV4 (TRPV4-/-) on cardiac function, both basally and following myocardial infarction. Cardiac function was similar in wild type and TRPV4-/- mice under normal conditions. By contrast, following myocardial infarction induced by permanent ligation of the left anterior descending coronary artery, left ventricular systolic and diastolic volumes were reduced and ejection fraction was significantly improved in TRPV4-/- when compared to wild type mice. Consistent with the differences in chamber volumes between TRPV4-/- and wild type mice, myocardial infarction induced a significant increase in heart weight and left ventricular mass index in wild type, but not in TRPV4-/- mice. In a separate cohort of mice, we also investigated the effect of genetic deletion of TRPV4 on infarct size after a 30 min myocardial ischemia and 24 hours reperfusion. There were no differences in myocardial infarct size or area at risk in TRPV4-/- and wild type mice after ischemia/reperfusion injury. These results suggest that TRPV4 does not mediate acute myocardial ischemic injury, but does play an important role in ventricular remodelling known to correlate with poor outcomes following acute myocardial infarction.
Volumen total y ahusamiento para Pinus patula Schiede ex Schltdl. et Cham. en tres condiciones de bosque

El objetivo de este estudio fue estimar el volumen total y comercial en pie de plantaciones de Pinus patula en Zacualpan, Veracruz, y comparar el ahusamiento-volumen con dos poblaciones de P. patula procedentes de bosques naturales, en Zacualtipan, Hidalgo e Ixtlan, Oaxaca. Los datos obtenidos se ajustaron al modelo de Fang, el cual estima el ahusamiento, volumen y permite analizar los tipos dendrometricos. Los resultados del analisis indican un factor de forma de los arboles diferente para cada condicion de bosque analizada: 0.50 para arboles creciendo en el sistema de plantacion, 0.46 para arboles creciendo en bosque natural bajo manejo intensivo (Zacualtipan), y 0.44 para arboles de bosque natural creciendo en condiciones de manejo extensivo (Ixtlan). La forma del arbol varia segun la silvicultura aplicada y se sugiere que arboles relativamente pequenos (menores de 25 cm de diametro) y jovenes creciendo en plantaciones con poda, concentran una mayor cantidad de volumen en el fuste y se deberia considerar solo un punto de inflexion sobre el fuste
Characterization of organic aerosols from a Chinese Mega-City during winter : 1 predominance of fossil fuel combustion 2 3

3 Md. Mozammel Haque, Kimitaka Kawamura, Dhananjay K. Deshmukh, Cao 4 Fang , Wenhuai Song, Bao Mengying and Yan-Lin Zhang 5 6 1 Yale-NUIST Center on Atmospheric Environment, Department of Applied 7 Meteorology, Nanjing University of Information Science and Technology, Nanjing 8 210044, China 9 2 Chubu Institute for Advanced Studies, Chubu University, Kasugai 487-8501, Japan 10 Key Laboratory of Meteorological Disaster, Ministry of Education & Collaborative 11 Innovation Center on Forecast and Evaluation of Meteorological Disasters, Nanjing 12 University of Information Science and Technology, Nanjing 210044, China 13 14
BACTERIAL DNA GYRASE IS NOT THE TARGET OF QUINOLINE - BASED ANTI - TUBERCU LOSIS COMPOUNDS

Few quinoline - based synthetic compounds (2, 8 Dicyclopentyl - 4 - methyl quinoline and 2, 8 Dicyclohexyl - 4 - methyl quinoline), the synt hesis of which have been already shown by our medicinal chemistry group, were found to be potent inh ibitor of mycobacterial growth . Based on the results of cell culture - based cell killing assays using DNA gyrase positive E. coli strains, we presumed that b acterial DNA gyrase might be a probable target of quinolines. The resemblance of the basic skeletal structural moiety of quinolone and quinoline inspired us to hypothesize that these quinolines might inhibit DNA gyrase. While the non - gyrase inhibitors like ethambutol and isoniazid did not inhibit the growth of these strains. The genesis of the notion of using E. coli DNA gyrase as an alternative to DNA gyrase from the pathogenic Mycobacterium , stems from the fact that E. coli DNA gyrase is found to be about eighty times more sensitive to the action of quinolones than the Mycobacterium DNA gyrase . Therefore, we had used E. coli DNA gyrase as a model enzyme for studying the action of some synthetic quinoline compounds synthesized by us . In the present work, we have used cell killing assay, gel electrophoresis assay (for DNA supercoiling) and UV spectroscopy - based coupled assay (for ATP hydrolysis) for characterizing the activity of DNA gyrase. Quinolones exhibited low IC 50 values as compared to the studied quin olines on DNA gyrase positive E. coli strains We found that although quinolones are the potent inhibitors of supercoiling activity of E. coli DNA gyrase, quinolines are not. We further found that ATPase activity of E. coli DNA gyrase (Non - specific inhibito r) was inhibited to a very minor extent in the presence of very high concentration of these synthetic quinolines. DNA gyrase is not the primary target of these synthetic quinolines (2, 8 Dicyclopentyl - 4 - methyl quinoline and 2, 8 Dicyclohexyl - 4 - methyl quino line).
Modelling the surface and subsurface Martian radiation environment: Implications for astrobiology

The damaging effect of ionising radiation on cellular structure is one of the prime limiting factors on the survival of life in potential astrobiological habitats. Here we model the propagation of solar energetic protons and galactic cosmic ray particles through the Martian atmosphere and three different surface scenarios: dry regolith, water ice, and regolith with layered permafrost. Particle energy spectra and absorbed radiation dose are determined for the surface and at regular depths underground, allowing the calculation of microbial survival times. Bacteria or spores held dormant by freezing conditions cannot metabolise and become inactivated by accumulating radiation damage. We find that at 2 m depth, the reach of the ExoMars drill, a population of radioresistant cells would need to have reanimated within the last 450,000 years to still be viable. Recovery of viable cells cryopreserved within the putative Cerberus pack‐ice requires a drill depth of at least 7.5 m.