Miracle-dz/UniFAR-FTUs huggingface dataset:
Primordial odontogenic tumor with prominent calcifications: A rare case report

Primordial odontogenic tumor (POT) is a rare odontogenic tumor. It is a new entity in the latest edition of the World Health Organization classification in 2017. In the English-language literature, only 14 cases have been documented. Most POTs show a well-defined unilocular radiolucency surrounding a crown of an unerupted molar, resembling a dentigerous cyst. Microscopically, POT may be difficult to distinguish from odontogenic myxoma, ameloblastic fibroma, hyperplastic dental follicle and dental papilla. Here, we reported a case of POT in a 17-year old female presenting with an asymptomatic bony hard swelling at the left posterior mandible. Interestingly, this case shows unique radiographic and microscopic features with prominent calcifications and stellate reticulum-like structures. These characteristics have rarely been described in all previously reported POTs. Importantly, this case is the first case of POT demonstrating radiopacity in the radiographs. We encourage more cases of POTs to be documented as POTs may have more variations in radiographic and microscopic features. Importantly, oral radiologists, surgeons and pathologists must be aware of this new and rare tumor in order to avoid a misdiagnosis and an inappropriate treatment. Key words:Calcification, mandible, odontogenic tumor, primordial odontogenic tumor.
Physical birth outcomes in neonates prenatally exposed to buprenorphine - our first experiences

Introduction/Objective. Buprenorphine appears generally similar to, and in some cases superior to, methadone in terms of maternal, fetal, and neonatal outcomes. The objective of the study was to assess some physical birth outcomes in neonates prenatally exposed to buprenorphine. Methods. During a seven-year period, nine patients have been treated with buprenorphine during their pregnancy. All women underwent interview, clinical investigations, biochemical analysis, toxicological screening, viral markers for hepatitis B, C, HIV, with regular check-ups by an obstetrician and a psychiatrist. Newborn outcomes included: birth weight in grams, birth length in centimeters, physical anomalies, head/chest circumference in centimeters, Apgar score at 1 minute / 5 minutes, gestational age (weeks), newborn length of hospital stay in days, breast-feeding, the newborn? s need for pharmacologic treatment after delivery. Results. The mean birth weight was 2,991.11 ? 37 g; birth length was 49.44 ? 2.29 cm; head circumference was 33.11 ? 0.78 cm; chest circumference was 32.33 ? 1 cm; first minute Apgar score was 8.22, fifth minute 9.22; age at delivery was 38.77 ? 1.09 weeks; hospitalization after delivery 4.44 ? 1.13 days. None of the newborns had physical anomalies. Six of the newborns were breastfed. Conclusion. Buprenorphine is a safe and important part of a complete comprehensive treatment approach in pregnant women with opioid use disorder. Buprenorphine treatment of maternal opioid use disorder indicated a low risk of preterm birth, normal birth weight and length, head and chest circumference, Apgar score, short hospitalization after delivery.
The knowledge of the dentists in dental clinics in Kerman City, Iran, about ocular complications after local anesthesia

BACKGROUND AND AIM: Ocular disorder like, diplopia, mydriasis, blurred vision, ptosis, exophthalmos, and blindness (permanent or temporary) are infrequent complications of an injection of local anesthetics in mouth.The main purpose of this study was to survey the dentist’s knowledge and attitude about ocular disorders due to intra-oral anesthetics injection. METHODS: A three-part questionnaire including demographic data and questions on knowledge and attitude about ocular complication was distributed among 197 dentists in Kerman, Iran. Data analysis were performed using the SPSS. RESULTS: Of the study participants, 7.6% did not have any knowledge regarding the ocular complications after local anesthetics injection and 10.7% indicated that eye problems have not been occurred following the dental anesthesia. Among the participants who were aware of this issue expressed self-experience in the clinical practice as the major source of their information, while just 2.0% indicated that their awareness on the ocular complications was from the studies published. In addition, this lack of knowledge in general dentists was more than the specialists. CONCLUSION: The knowledge of the dentists regarding the ocular complications due to anesthesia in the present survey investigation is not satisfactory and needs enhancement. There is a necessity for precise protocol for dentists in recognizing and managing ocular complications by intra-oral anesthetics injections.
utilization of self care brochure for relieving mothers minor discomforts during pregnancy

The aim of this study was to investigate the utilization of self-care brochure forsss relieving mother’s minor discomforts during pregnancy. Methods: An interventional quasi-experimental research design was carried out at Antenatal Clinic of Mansoura University Hospital-Mansoura City on 90 primigravida women at≤34 gestational weeks, who were selected by simple random sampling technique. They were free from any medical and obstetric problems, can read and write, and reported one or more of the associated pregnancy minor discomforts. They were divided into either control or intervention group 45 per each group. The intervention group: had received a self-care brochure beside the routine antenatal care. While the control group had received the routine antenatal care only. Mother’s attitude regarding self-care was assessed utilizing Likert scale. Results: Providing the pregnant mothers with a self-care brochure was associated with relieving most of the self-reported pregnancy discomforts among the study group compared to those of the control group as reported by women 3 weeks’ post intervention. Conclusion: The intervention group had agreed that the self-care guide is easy to be used and the majority of them reported that they will use it in the future pregnancy.
Swallowing Physiology and Impairment in Individuals with Amyotrophic Lateral Sclerosis (ALS)

Dysphagia, or swallowing impairment, is a common symptom of bulbar disease in Amyotrophic Lateral Sclerosis (ALS). Dysphagia in ALS significantly affects quality of life and places an affected individual at risk of developing chest infections, becoming malnourished, and shortened life expectancy. The purpose of this doctoral thesis is to provide a comprehensive overview of swallowing physiology in ALS and elucidate potential relationships between swallowing physiology and clinical swallowing function. The first chapter of this thesis provides an introductory overview of normal swallowing, dysphagia, and ALS pathology, highlighting commonly reported swallowing impairments and associated complications in individuals with ALS. Chapter 2 builds on this discussion through a comprehensive review of research literature on dysphagia in ALS. Following scoping review methodology, we identified research trends and areas for further exploration, including a need for further quantitative analysis of swallowing physiology. Chapter 3 involves a retrospective, cross-sectional study of swallowing physiology in ALS, using quantitative videofluoroscopic analysis. Measures of pharyngeal area at maximum constriction and swallow-related hyoid kinematics were obtained and compared against reference data to test face validity of the measures and identify changes associated with disease pathology. Through this analysis, we identified reductions in maximum pharyngeal constriction and anterior hyoid movement, compared to healthy reference data. Further, we revealed relationships between enlarged maximum pharyngeal constriction areas and measures of swallowing inefficiency.
Influence of Expectation Confirmation, Network Externalities, and Flow on Use of Mobile Shopping Apps

ABSTRACT The purpose of the current research is to examine the influence of expectation confirmation, network externalities, and flow on word-of-mouth intention and continued use of mobile shopping apps. A structured online survey questionnaire is used to collect data from 363 users of mobile shopping apps. Structural equation modeling is used to analyze the research model. The findings reveal that indirect network externalities, i.e., perceived complementarity, influence perceived usefulness of the mobile shopping app. Users’ confirmation of expectations significantly influences perceived usefulness, satisfaction, and continuance intention to use mobile apps. Satisfaction is found to be a significant predictor of continuance intention and word-of-mouth intention. Flow influences satisfaction of users, perceived usefulness, and continuance intention. Word-of-mouth intention is found to be an important post-adoption behavioral outcome. The results provide valuable theoretical insights for academics and managerial implications for providers of mobile shopping apps.
Urinary tract infections in children: an overview of diagnosis and management

Urinary tract infections (UTIs) are a common and potentially serious bacterial infection of childhood. History and examination findings can be non-specific, so a urine sample is required to diagnose UTI. Sample collection in young precontinent children can be challenging. Bedside dipstick tests are useful for screening, but urine culture is required for diagnostic confirmation. Antibiotic therapy must be guided by local guidelines due to increasing antibiotic resistance. Duration of therapy and indications for imaging remain controversial topics and guidelines lack consensus. This article presents an overview of paediatric UTI diagnosis and management, with highlights of recent advances and evidence updates.
[Equipment for diagnostics, laboratory analyses and treatment in out-of-hours services].

BACKGROUND Availability of equipment for diagnostics and treatment in out-of-hours services in Norway is not documented and no guidelines exist on requirements for the various types of equipment (including drugs) needed. A knowledge basis on status and needs should be established so minimum requirements can be developed. MATERIAL AND METHODS The National Centre for Emergency Primary Health Care sent a questionnaire on availability of diagnostic equipment, laboratory tests, medication and quality assurance systems to all 261 municipal out-of-hours services in Norway in February 2006. RESULTS 223/261 (86 %) of the services responded. 150 used the same office as a day-time practice, 59 had their own office and 14 were localised in a hospital/ emergency care unit. Services located in GP surgeries with a daytime-practice had a wider range of equipment, laboratory tests and medicines. Physicians on duty in the out-of-hours services with shared facilities did much of the laboratory work, but the quality control was done by the personnel at daytime. 27 % of the independent services did not have external control of their laboratory work (they were not members of the Norwegian Quality Improvement of Primary Care Laboratories). GPs were trained on acute medical situations more than once a year in 52 % of all the out-of-hours-services, but for only 40 % in the independent services. Other personnel were trained more than once a year in 74 % of the independent services. INTERPRETATION Availability of equipment and laboratory test repertoire for GPs on duty at out-of-hours services seems to depend on whether the services are shared with GP surgeries and also used at daytime, and the distance to ambulance, hospital and pharmacy. Lack of routines for laboratory work and low training frequency in acute medical procedures may lead to poor quality of the analyses and lower competence than needed.
Hyperbaric bupivacaine 0.5% versus hyperbaric bupivacaine 0.5% & fentanyl in spinal anaesthesia: Haemodynamic changes and adverse effects

Cardiovascular system is the most important physiologic response to spinal anaesthesia. They are mediated by combined autonomic denervation and higher levels of neural blockade and the added effects of vagal nerve intervention. The level of sympathetic blockade determines the magnitude of cardiovascular responses to spinal anaesthesia. Higher the level of neural blockade the greater would be change in cardio-circulatory parameters. In the presence of partial sympathetic blockade a reflex increase in sympathetic activity occurs in sympathetically intact areas. The result is vasoconstriction that tends to compensate for peripheral vasodilatation taking place in sympatheticlly denervated areas. 100 patients belonging to American Society of Anaesthesiology (ASA) Grade-I & II physical status, scheduled for elective surgeries of lower abdomen and lower extremities aged between 18-60 years were included in this study. Hypotension was noted in 6 patients in group I and 5 patients in group II. One patient complained of itching (pruritis) over the neck and shoulders in group II and none in group I. Intrathecal fentanyl along with bupivacaine gives a more reliable anaesthesia, better operative conditions, patient comfort and prolonged duration of analgesia with minimal side effects.
Fast, volumetric live-cell imaging using high-resolution light-field microscopy

Visualizing diverse anatomical and functional traits that span many spatial scales with high spatio-temporal resolution provides insights into the fundamentals of living organisms. Light-field microscopy (LFM) has recently emerged as a scanning-free, scalable method that allows for high-speed, volumetric functional brain imaging. Given those promising applications at the tissue level, at its other extreme, this highly-scalable approach holds great potential for observing structures and dynamics in single-cell specimens. However, the challenge remains for current LFM to achieve subcellular level, near-diffraction-limited 3D spatial resolution. Here, we report high-resolution LFM (HR-LFM) for live-cell imaging with a resolution of 300-700 nm in all three dimensions, an imaging depth of several micrometers, and a volume acquisition time of milliseconds. We demonstrate the technique by imaging various cellular dynamics and structures and tracking single particles. The method may advance LFM as a particularly useful tool for understanding biological systems at multiple spatio-temporal levels.
Analysis on Feature Extraction and Classification of Rice Kernels for Myanmar Rice Using Image Processing Techniques

The paper presents the analysis on feature extraction and classification of rice kernels for Myanmar rice using image processing techniques. There are seven steps to analyze the image processing techniques. The classification of export-rice quality is a great challenge in agricultural industries. The development of modern technology-based methods for rice quality classification is currently necessary to provide a reliable and consistent rice quality to consumers. An image processing algorithm has been implemented the analysis and classification the rice kernels in Myanmar. The proposed method is based on real-field feature and KNN classifier. Then, a series of measurements were done using image processing techniques on three classes of Paw-San rice in Myanmar. The real-field feature of Paw-San rice is percentage of broken rice contained in the batch. At 30 tests are conducted for each class of Paw-San rice. The simulation results show that the proposed method can confirm the classification accuracy in the range of 83~100% for the three grades.
Does breastfeeding have a long-term positive effect on dental occlusion?

Background Breastfeeding produces beneficial effects on a baby’s early growth and development, and general well-being. Some studies have associated breastfeeding with better occlusal development. The aim of this study was to assess the long-term effect of breastfeeding on occlusal development in children. Material and Methods A retrospective cohort study was conducted to evaluate the occlusions of 320 children belonging to the Spanish INMA Project cohort, monitored from gestation onwards. The association between the duration of breastfeeding and different occlusal traits in mixed dentition (overjet, overbite, openbite, midline displacement, incisor crowding, incisor spacing, diastema, maximum maxillary and mandibular irregularity, anterior and posterior crossbite) at the age of 9 was assessed, as well as the orthodontic treatment need as determined by the “Index of Orthodontic Treatment Need” and the “Dental Aesthetic Index”. Results A statistically significant association between the duration of breastfeeding and posterior crossbite was found. The Odds Ratio for posterior crossbite was 2.52 (IC 95% 1.34-4.74) for children breastfed up to 16 weeks, 0.56 (IC 95% 0.29-1.08) for children breastfed 16 to 45 weeks, and for more than 45 weeks of breastfeeding it was 0.50 (IC 95% 0.19-1.32). No association was found between breastfeeding and the other examined occlusal traits, nor with the orthodontic treatment need. Conclusions Breastfeeding for less than 4 months increases the risk of posterior crossbite. However, breastfeeding duration is not linked to other malocclusion traits nor is it linked to the orthodontic treatment need of nine-year-old children. Key words:Breastfeeding, occlusion, malocclusion, dental development.
Evaluating the Usability of A Group Support System Using Co-Discovery

Group Support Systems (GSSs) have emerged as a new type of information system to aid group decision-making. With the proliferation of such systems in organizations, evaluation of GSSs is becoming increasingly important. This paper reports the evaluation of an existing GSS. Our usability framework consists of nine dimensions: visual clarity, consistency, compatibility, informative feedback, explicitness, flexibility and control, error prevention and correction, ease of learning, and ease of use. We make use of the co-discovery method where teams of two participants perform tasks together while being observed. The study involves questionnaires and interview sessions. The strengths and weaknesses of the research method, research framework, and research instruments used in this evaluation are also discussed.
Re-identification for Online Person Tracking using Discriminative Spatio-temporal Features

The goal of this dissertation is to develop an effective online multi-person multicamera tracking system without unrealistic assumptions. The key technical elements necessary for this include: (i) transformation of detection of each person into a feature space to identify individuals and handle changes in position and posture, (ii) automated procedure to extract features and form trajectories without the need of prior information of individuals, and (iii) learning the evolution of the frame-by-frame spatial representation with the temporal dependencies. The thesis presents a novel model named Continuous Entity Association that combines the two acts of tracking within and across cameras and reformulates it as a single problem of continuous re-identification. The approach unifies the two separate tasks and presents a much clearer and simpler online solution which has the advantage of not requiring temporally contiguous sequences of video frames for tracking. This is accomplished by extracting appearance and facial features, and modeling location constraints across cameras. The approach is validated by using a simple and efficient inference algorithm. Next, a discriminative spatio-temporal learning approach for online tracking using LSTM networks is proposed. The idea is to exploit LSTM’s temporal step-by-step functionality to identify detections as belonging to the same individual and recovering from past errors in associating different individuals to a particular trajectory. State-of-the-art tracking results are obtained on two large publicly available datasets, CamNeT and DukeMTMC.
The mechanisms and consequences of bacterial colonisation in chronic obstructive pulmonary disease

2 Author’s Declaration . 4 Acknowledgments . 6 Publications and Abstracts . 7 Original articles – first author . 7 Original articles – other author . 7 Original article manuscripts in preparation . 8 Reviews . 8 Oral presentations . 9 Poster discussions . 10 Table of
High lncRNA MEG3 expression is associated with high mortality rates in patients with sepsis and increased lipopolysaccharide-induced renal epithelial cell and cardiomyocyte apoptosis

Long non-coding RNA (lncRNA) maternally expressed 3 (MEG3) has been reported to be a key component in cancer biology. Preliminary microarray data from a previous study indicated that lncRNA MEG3 expression was altered in plasma of patients with sepsis. The present study found that the plasma levels of lncRNA MEG3 were significantly higher in sepsis patients compared with healthy controls. Patients were subsequently divided into high and low lncRNA MEG3 expression groups according to the Youden's index. Patients from the high lncRNA MEG3 expression group exhibited a significantly higher mortality rate compared with those from the low lncRNA MEG3 expression group. According to treatment outcomes, patients were divided into survival and mortality groups. It was observed that the pre-therapy expression levels of lncRNA MEG3 were significantly higher in mortality group compared with the survival group. Cell experiments in vitro revealed that lncRNA MEG3 overexpression and silencing using siRNA promoted and inhibited renal epithelial cell and cardiomyocyte apoptosis induced by lipopolysaccharide, respectively. In conclusion, these data suggest that lncRNA MEG3 overexpression may be involved in sepsis, and the downregulation of lncRNA MEG3 may serve as a potential therapeutic target for sepsis.
Night Eating Syndrome and Food Addiction in Turkish Population

Objectives: The aim of this study was to determine the prevalence of food addiction (FA) and night eating syndrome (NES) and to investigate any correlation between them in Turkish population. Materials and Methods: Subjects registered with family medicine centers were randomly invited to participate in the study (415 volunteers). Participants were evaluated with a socio-demographic data form, the Yale Food Addiction Scale (YFAS) and the Night Eating Questionnaire (NEQ). Results: A total of 295 subjects, including 160 females and 135 males, were evaluated in our study. The mean age of the participants was 33.78±10.72 and the mean BMI was 25.11±4.63. 7.8% of the subjects had FA according to the YFAS, and 13.2% had NES according to the NEQ. The prevalence of a coexistence of NES and FA was 2%. Using Pearson correlation analysis, a positive correlation was established between BMI and NEQ (r=0.14, p<0.01) and a positive correlation was found between total scores from the NEQ and the YFAS (r=0.14, p<0.01). With multiple linear regression analysis, it was demonstrated that 18.4% of total NEQ scores could be explained by eight YFAS symptom scores (p<0.001). Conclusion: It should be kept in mind that normal-weight, overweight or obese individuals may have NES or FA or both. Therefore, it could be useful to assess these problematic eating behaviors in individuals presented to family medicine outpatient clinics and to refer those with these problematic eating behaviors to relevant treatment centers.