Miracle-dz/UniFAR-FTUs huggingface dataset:
Psychologists' and Social Workers' Self-Descriptions Using DSM—IV Psychopathology

There is limited information on mental health of psychologists and social workers despite their rendering mental health services, so their subjective perception of mental disorder was explored via a self-evaluation survey in which they self-diagnosed the presence of DSM-IV disorders within themselves. The sample of 128 professionals included 63 psychologists and 65 social workers. The presence of Axis I traits was reported by 81.2%, the three most frequent traits being mood, obsessive-compulsive disorder, and eating disorder. Axis II traits were reported by 73.4% of subjects, the three most frequent conditions being narcissistic, avoidant, and obsessive-compulsive personality traits. While a high percentage of subjects reported the presence of either an Axis I or Axis II disorder, the average severity reported was low. More psychologists reported on mood, social phobia, and eating problems than social workers, while the latter reported more on psychotic problems. Psychologists reported more Axis II traits, especially paranoid, narcissistic, and avoidant subtypes. More women than men reported eating problems, while more men reported schizoid and avoidant personality traits. In conclusion, manifestations of subthreshold psychiatric conditions were prominently reported. These findings suggest encouraging mental health care professionals to explore treatment for problems if present.
Adaptive output-feedback consensus protocol design for linear multi-agent systems with directed graphs

This paper addresses the output feedback consensus protocol design problem for general linear multi-agent systems with directed communication graphs. By proposing a new method called adding an extra observer, two novel adaptive output feedback consensus protocols are proposed to achieve consensus for any strongly connected directed graph. The proposed adaptive output feedback protocols are fully distributed, relying on only the agent dynamics and the local output information of neighboring agents. A sufficient condition for the existence of the proposed adaptive protocols is that each agent is stabilizable and detectable.
Task‐dependent changes in the responses to low‐threshold cutaneous afferent volleys in the human lower limb.

1. In seven human subjects who were standing without support the sural nerves were stimulated electrically using trains of non‐painful stimuli (five pulses at 300 Hz), designed to activate afferents from cutaneous mechanoreceptors. The reflex effects of the stimulus train on different muscles of the ipsilateral and contralateral legs were sought in post‐stimulus averages of rectified EMG. Changes in the pattern of reflex influence were investigated when the subjects maintained different postures. 2. Clear reflex responses were seen in ipsilateral tibialis anterior, soleus, biceps femoris and vastus lateralis, but only when the muscles were actively contracting. In each muscle, inhibition was the dominant reflex response within the first 100 ms. In four of the seven subjects, reflex changes were detectable in the contralateral tibialis anterior and soleus, the peak‐to‐peak modulation within the first 200 ms being 25‐50% of that for the homologous ipsilateral muscle. 3. When subjects attempted to stand on a tilted platform, an unstable platform or on one leg with the other flexed, different combinations of muscles were active, involving both flexors and extensors or predominantly flexors or predominantly extensors. In each posture the reflex effects were demonstrable only in the active muscles. 4. With ipsilateral tibialis anterior, there were task‐dependent changes in the short‐latency components of the EMG response, approximately 60 ms and 80 ms after the stimulus. When seated performing voluntary contractions these components were difficult to define, and when standing on a platform tilted toe‐up they were small. When the ipsilateral leg was flexed or when standing on an unstable base, these early components were more prominent in each subject. With contralateral tibialis anterior, the dominant reflex pattern was inhibition when seated and contracting voluntarily, and facilitation during bipedal stance tilted toe‐up. These changes in reflex pattern could not be explained by different levels of background contraction. 5. It is concluded that cutaneous mechanoreceptors of the foot have widespread reflex actions on muscles throughout both limbs, particularly the ipsilateral limb, and that the reflex pattern in different muscles and within a single muscle may change dependent on the task that the subject is undertaking. These task‐dependent changes indicate plasticity in the expression of cutaneous reflex activity, affecting both short‐latency spinal as well as long‐latency pathways.
Methods, rules and limits of successful self-assembly

The self-assembly of structured particles into monodisperse clusters is a challenge on the nano-, micro- and even macro-scale. While biological systems are able to self-assemble with comparative ease, many aspects of this self-assembly are not fully understood. In this thesis, we look at the strategies and rules that can be applied to encourage the formation of monodisperse clusters. Though much of the inspiration is biological in nature, the simulations use a simple minimal patchy particle model and are thus applicable to a wide range of systems. The topics that this thesis addresses include: Encapsulation: We show how clusters can be used to encapsulate objects and demonstrate that such `templates' can be used to control the assembly mechanisms and enhance the formation of more complex objects. Hierarchical self-assembly: We investigate the use of hierarchical mechanisms in enhancing the formation of clusters. We find that, while we are able to extend the ranges where we see successful assembly by using a hierarchical assembly pathway, it does not straightforwardly provide a route to enhance the complexity of structures that can be formed. Pore formation: We use our simple model to investigate a particular biological example, namely the self-assembly and formation of heptameric alpha-haemolysin pores, and show that pore insertion is key to rationalising experimental results on this system. Phase re-entrance: We look at the computation of equilibrium phase diagrams for self-assembling systems, particularly focusing on the possible presence of an unusual liquid-vapour phase re-entrance that has been suggested by dynamical simulations, using a variety of techniques.
Editorial. Problems, challenges and opportunities: the small business as a setting for management accounting research

This special issue is devoted to management accounting in the small firm. It comprises five studies which address various aspects of this topic, which have been undertaken from different perspectives and which involve different research methodologies. The editorial below reviews the potential for and significance of research in this area and assess the contribution made by the five studies.
Total Serum Cholesterol and Suicidality in Anorexia Nervosa

Objective: No published study has evaluated the relationship between serum cholesterol and suicidality in anorexia nervosa (AN). Aims: To assess psychiatric and nutritional correlates of serum cholesterol in a sample of AN patients. Methods: Serum cholesterol and nutritional status were evaluated in a sample of 74 AN patients, before starting any type of refeeding. All subjects underwent a structured clinical interview and completed the Hopkins Symptom Checklist. Results: Subjects who reported previous suicide attempts, impulsive self-injurious behavior, or current suicidal ideation showed significantly lower cholesterol levels than subjects without suicidality. Cholesterol levels were negatively correlated with the severity of depressive symptoms in all the patients with the exception of those with recurrent binge eating. A multivariate analysis showed that the relationships between cholesterol levels and suicidal behavior and ideation do not seem to be affected by the nutritional and metabolic factors considered in the study. Conclusions: Notwithstanding the influence of important metabolic factors affecting cholesterolemia in AN, our research tends to confirm previous studies that have found an association between low cholesterol levels and suicidality.
Are Academics Wrongly Assuming Bioscience Students Have the Transferable Skills and IT Competency They Need to Be Successful Beyond the Degree?

Acquisition and development of key transferable skills is an important requirement for all graduate employees. The aim of the current study was to investigate a potential skills shortage in bioscience students and, if revealed, explore ways of addressing it. A research questionnaire, which included mixed methodology, was used to collate information from a cohort of students across levels four, five and six enrolled on Biological and Biomedical Science undergraduate programmes. A total of 131 students participated in the study. The questionnaire was designed to establish students’ confidence using packages such as the Microsoft Office Suite and whether they required additional support with certain programmes; further areas explored students’ self-assessment of key skills such as written communication, referencing, self-confidence, presentation skills and team working. No statistically significant gender differences (males n = 49; females n = 82) were observed in participant responses (p> .05). Of the total number of students included in the survey, 91% rated themselves as competent using Word and 64% felt least confident using statistical software and performing statistical analysis in Microsoft Excel. Comparing responses by year of study revealed no statistical differences in reported abilities (p> .05). These findings indicate areas of potential key skills shortages, particularly using data handling software, which may not be sufficiently addressed if prior knowledge is incorrectly assumed. Nearly half of students (50% of level six students) who were graduating felt unprepared performing statistical analysis in Excel. Inclusion of an IT component to support skills development in data handling software at Level 4 is recommended and teaching key software packages is necessary. Furthermore, opportunities for students to develop their presentation skills and report writing abilities are required. This in turn should improve the student experience and develop the transferable skills which are increasingly sought by employers.
Investigating the association of rs2910164 with cancer predisposition in an Irish cohort

Introduction MicroRNAs (miRNAs) are small noncoding RNA molecules that exert post-transcriptional effects on gene expression by binding with cis-regulatory regions in target messenger RNA (mRNA). Polymorphisms in genes encoding miRNAs or in miRNA–mRNA binding sites confer deleterious epigenetic effects on cancer risk. miR-146a has a role in inflammation and may have a role as a tumour suppressor. The polymorphism rs2910164 in the MIR146A gene encoding pre-miR-146a has been implicated in several inflammatory pathologies, including cancers of the breast and thyroid, although evidence for the associations has been conflicting in different populations. We aimed to further investigate the association of this variant with these two cancers in an Irish cohort. Methods The study group comprised patients with breast cancer (BC), patients with differentiated thyroid cancer (DTC) and unaffected controls. Germline DNA was extracted from blood or from saliva collected using the DNA Genotek Oragene 575 collection kit, using crystallisation precipitation, and genotyped using TaqMan-based PCR. Data were analysed using SPSS, v22. Results The total study group included 1516 participants. This comprised 1386 Irish participants; 724 unaffected individuals (controls), 523 patients with breast cancer (BC), 136 patients with differentiated thyroid cancer (DTC) and three patients with dual primary breast and thyroid cancer. An additional cohort of 130 patients with DTC from the South of France was also genotyped for the variant. The variant was detected with a minor allele frequency (MAF) of 0.19 in controls, 0.22 in BC and 0.27 and 0.26 in DTC cases from Ireland and France, respectively. The variant was not significantly associated with BC (per allele odds ratio = 1.20 (0.98–1.46), P = 0.07), but was associated with DTC in Irish patients (per allele OR = 1.59 (1.18–2.14), P = 0.002). Conclusion The rs2910164 variant in MIR146A is significantly associated with DTC, but is not significantly associated with BC in this cohort.
Influence of light nuclei on neutrino-driven supernova outflows

We study the composition of the outer layers of a protoneutron star and show that light nuclei are present in substantial amounts. The composition is dominated by nucleons, deuterons, tritons and alpha particles; 3He is present in smaller amounts. This composition can be studied in laboratory experiments with new neutron-rich radioactive beams that can reproduce similar densities and temperatures. After including the corresponding neutrino interactions, we demonstrate that light nuclei have a small impact on the average energy of the emitted electron neutrinos, but are significant for the average energy of antineutrinos. During the early post-explosion phase, the average energy of electron antineutrinos is slightly increased, while at later times during the protoneutron star cooling it is reduced by about 1 MeV. The consequences of these changes for nucleosynthesis in neutrino-driven supernova outflows are discussed.
Seizure occurrence during ovulatory and anovulatory cycles in patients with temporal lobe epilepsy: a prospective study

We investigated the influence of ovulatory and anovulatory menstrual cycles on seizure occurrence in female patients with complex partial seizures. We prospectively documented seizures in relation to menstrual cycles (defined by measurement of basal body temperature and progesterone serum concentrations) in 39 female patients. One hundred and thirty‐two cycles of 35 patients entered final analysis. Only eight patients had anovulatory cycles, in 18 patients all cycles were ovulatory. In the remaining nine patients anovulatory as well as ovulatory cycles were documented. In ovulatory cycles the mean frequency of seizures during the days of menstruation was significantly higher as compared to the periovulatory or the luteal phase of the cycles. During anovulatory cycles seizure frequency was significantly lower during menstruation than in the remaining days of the cycles. Since progesterone is known to exhibit anticonvulsant effects, seizure occurrence during menstruation seems to be related to ovulatory cycles, possibly due to the premenstrual decrease of progesterone. Therapeutic recommendations for the treatment of seizures related to the menstrual cycle (catamenial seizures) include the administration of hormones, as progesterone (recommended especially for women with catamenial epilepsy who have a documented inadequate luteal phase) or the suppression of the menstrual hormonal cycle by synthetic gonadotropin releasing hormone analogs.
Dioxin Exposure and Cancer Risk: A 15‐Year Mortality Study after the “Seveso Accident”

Dioxin (2,3,7,8‐tetrachlorodibenzo‐para‐dioxin, or TCDD) is a powerful carcinogen in experimental animals, whereas the evidence in humans is limited. We examined cancer mortality from 1976 to 1991 among residents of Seveso, Italy, which was highly contaminated after an industrial accident. The area was divided into zones with decreasing exposure to dioxin (A = highest, B = lower, R = lowest). The population of a surrounding noncontaminated area was used as a reference group. Zone A was small (11,516 person‐years); in that zone, we saw a moderate increase in mortality from digestive cancer among women [relative risk (RR) = 1.5; 95% confidence interval (CI) = 0.5–3.5]. In zone B, we also saw excesses at digestive sites (83,610 person‐years), 10 years after the accident. Women had an increased mortality from stomach cancer (RR = 2.4; 95% CI = 0.8–5.7), and men had increased mortality from rectal cancer (RR = 6.2; 95% CI = 1.7–15.9). Hematologic neoplasms were increased. The highest risks were seen in zone B for leukemia in men (RR = 3.1; 95% CI = 1.3–6.4), multiple myeloma in women (RR = 6.6; 95% CI = 1.8–16.8), and Hodgkin's disease in both genders (RR = 3.3; 95% CI = 0.4–11.9 in men; and RR = 6.5; 95% CI = 0.7–23.5 in women). Soft tissue sarcoma was elevated only among zone R males (256,408 person‐years; RR = 2.1; 95% CI = 0.6–5.4). We found no increase for all‐cancer mortality or major specific sites (for example, respiratory among males, breast among females). The specific excesses that we observed were not explained by bias or confounding, and their association with dioxin exposure is plausible. The follow‐up is continuing.
Performance Comparison of OFDM Signal and CAP Signal Over High Capacity RGB-LED-Based WDM Visible Light Communication

We experimentally demonstrate a visible light communication (VLC) system based on a single commercially available RGB-type LED. High spectrally efficient carrierless amplitude and phase (CAP) modulation and orthogonal frequency-division multiplexing (OFDM) are adopted in the intensity-modulation and direct-detection VLC system of limited bandwidth. In order to achieve higher capacity of the uneven-frequency-response LED-based VLC system, OFDM signals are combined with the bit- and power-loading techniques, and CAP signals of various modulation are pre-emphasized to modulate one of the RGB chips. To reach the BER of less than 10-3, CAP and OFDM signals demonstrate the maximum data rates of 1.32 and 1.08 Gb/s, respectively, employing the blue chip. In addition to spectrally efficient formats, the wavelength-division-multiplexing (WDM) scheme is applied to further increase the capacity. After individually optimizing RGB chips, the maximum aggregate data rates of CAP and OFDM are 3.22 and 2.93 Gb/s, respectively, in our RGB-LED-based WDM VLC system. Hence, compared with OFDM, the CAP scheme shows competitive performance and provides an alternative spectrally efficient modulation for next generation optical wireless networks.
Alkaline battery‐induced tracheo‐oesophageal fistula

The rapid propagation of small electronic gadgets and toys controlled by alkaline batteries has brought these potentially lethal objects within the reach of small children whose natural instinct is to put everything into the mouth. Tracheo-oesophageal fistula caused by alkaline battery ingestion is a rare complication but highlights the hazards of ignoring these foreign bodies
Genetic analysis of the yeast cytoskeleton.

INTRODUCTION 259 THE CYTOSKELETON AND CELL CYCLE OF SACCHAROMYCES CEREVISIAE. 261 Mitotic Cell Cycle " 261 Conjugation 264 Structural Genes Specifying Filamentous Cytoskeletal Components 264 GENERATING MUTANTS DEFECTIVE IN THE FUNCTIONS OF KNOWN PROTEINS (PLAN B) 264 Isolation of Genes For Known Proteins by Homology 264 Isolation of Genes via Yeast Cytoskeletal Proteins 266 Constructing Null Mutations 267 Constructing Conditional-Lethal Mutants 268 IDENTIFICATION OF GENES BY MUTANT PHENOTYPE (PLAN A) 270 Identification of Mutations "lhat Affect Cytoskeletal Function 270 Identification of Genes Whose Products Interact 273 PHENOTYPES OF CYTOSKELETAL MUTATIONS 277 Tubulin Mutants 277 Nontubulin Mutants That Affect Spindle Function 278 Actin Mutants 280 Ten-Nanometer Filament Mutants 280 CONCLUSIONS 280
Legg-Calvé-Perthes disease in children with Down syndrome.

OBJECTIVE The aim of this study was to describe the features of Perthes disease in patients with Down syndrome. METHODS The data of this retrospective case series were collected between 2000 and 2011. Patients were assessed according to demographic, clinical and radiographic classifications. RESULTS The study included 7 hips of 6 patients (5 males, 1 female). Mean age at first visit was 6.1 (range: 3.5 to 12.7) years and mean follow-up period was 52.3 (range: 30.2 to 90.8) months. Initial complaints were pain and limping with limited range of motion at the first visit. Range of motion tended toward early improvement despite continuous radiographic changes. One patient had late onset Perthes disease and developed rapid femoral head collapse managed with total hip arthroplasty. CONCLUSION Perthes disease in children with Down syndrome must be followed despite clinical improvement. Radiographic characteristics of Perthes disease in patients with Down syndrome do not differ from those without it.
How Many Kinds of Reading Disabilit Are There?

This paper reviews the recent research bearing on the single cause/multiple cause controversy in regard to reading disabilities. The inadequacy of the common practice of comparing a group of disabled readers with a control group is noted. A number of single-factor theories are reviewed, including those of Orton, Levinson, Delacato, Bender, Frostig, and Vellutino. Recent research pointing to multiple causation is summarized, including clinically based studies and those employing statistical techniques such as cluster analysis and Q technique. There seem to be at least three main types of reading disability and possibly several less common ones, with great individual variations in constitutional, environmental, and motivational handicaps.
Survival, Body Weight, and Spontaneous Neoplasms in Ad Libitum- Fed and Food-Restricted Fischer-344 Rats

Ad libitum- fed (AL) and food-restricted (FR) Fischer-344 male and female rats were monitored for survival, body weight, and spontaneous neoplasms. Mean and maximal lifespans for each group were inversely related to mean body weights. AL males were the shortest lived (mean lifespan 101 wk) followed by AL females (118 wk), FR males (125 wk), and FR females (132 wk). Gross and microscopic examinations were performed on 851 rats from cross-sectional and longevity components of the study. In FR groups, the incidence of mammary gland fibroadenomas, testicular interstitial cell tumors, and pituitary neoplasms was decreased while the latency of these neoplasms was increased. In longevity components, most FR groups had a higher incidence of leukemia than AL cohorts, but all FR groups had a higher mean age at death for the rats with leukemia. Higher leukemia rate in the FR groups was thought to be a result of their extended mean lifespan.