Miracle-dz/UniFAR-FTUs huggingface dataset:
Imagining a Better Memory

Recent research has demonstrated that self-referential strategies can be applied to improve memory in memory-impaired populations. However, little is known regarding the mnemonic mechanisms and relative effectiveness of self-referential strategies in memory-impaired individuals. This study investigated the benefit of a new self-referential strategy known as self-imagination, traditional self-referential strategies, and non-self-referential strategies on free recall in memory-impaired patients with acquired brain injury and in healthy control respondents. The data revealed an advantage of self-imagining in free recall relative to all other strategies in patients and control respondents. Findings also demonstrated that, in the patients only, a self-referential strategy that relied on semantic information in self-knowledge was more effective than a self-referential strategy that relied on autobiographical episodic information. This study provides new evidence to support the clinical utility of self-imagining as a memory strategy and has implications for the future development and implementation of self-referential strategies in memory rehabilitation.
Effects of Boswellia Serrata Roxb. and Curcuma longa L. in an In Vitro Intestinal Inflammation Model Using Immune Cells and Caco-2

Inflammatory bowel diseases, which consist of chronic inflammatory conditions of the colon and the small intestine, are considered a global disease of our modern society. Recently, the interest toward the use of herbal therapies for the management of inflammatory bowel diseases has increased because of their effectiveness and favourable safety profile, compared to conventional drugs. Boswellia serrata Roxb. and Curcuma longa L. are amongst the most promising herbal drugs, however, their clinical use in inflammatory bowel diseases is limited and little is known on their mechanism of action. The aim of this work was to investigate the effects of two phytochemically characterized extracts of B. serrata and C. longa in an in vitro model of intestinal inflammation. Their impact on cytokine release and reactive oxygen species production, as well as the maintenance of the intestinal barrier function and on intestinal mucosa immune cells infiltration, has been evaluated. The extracts showed a good protective effect on the intestinal epithelium at 1 µg/mL, with TEER values increasing by approximately 1.5 fold, compared to LPS-stimulated cells. C. longa showed an anti-inflammatory mechanism of action, reducing IL-8, TNF-α and IL-6 production by approximately 30%, 25% and 40%, respectively, compared to the inflammatory stimuli. B. serrata action was linked to its antioxidant effect, with ROS production being reduced by 25%, compared to H2O2-stimulated Caco-2 cells. C. longa and B. serrata resulted to be promising agents for the management of inflammatory bowel diseases by modulating in vitro parameters which have been identified in the clinical conditions.
Orthogonal Decomposition Methods to Analyze PIV, LDV, and Thermography Data of Thermally Driven Rotating Annulus Laboratory Experiments

Modeling Atmospheric and Oceanic Flows: Insights from Laboratory Experiments and Numerical Simulations provides a broad overview of recent progress in using laboratory experiments and numerical simulations to model atmospheric and oceanic fluid motions. This volume not only surveys novel research topics in laboratory experimentation, but also highlights recent developments in the corresponding computational simulations. As computing power grows exponentially and better numerical codes are developed, the interplay between numerical simulations and laboratory experiments is gaining paramount importance within the scientific community. The lessons learnt from the laboratory–model comparisons in this volume will act as a source of inspiration for the next generation of experiments and simulations.
Design, Development and Evaluation of Solid Dispersion incorporated Transdermal Gel of Benzoyl Peroxide

Benzoyl peroxide (BPO) an antiacne agent was chosen as model drug for present study is commonly used in topical formulations for the treatment of acne. The major drawback of Benzoyl Peroxide is its poor aqueous solubility. Solid Dispersion is an effective approach to improve its solubility and dissolution. To improve the permeability of Benzoyl Peroxide, the use of gel bases is a logical approach to increase the drug flux across the epithelium. Penetration rate of drugs through the stratum corneum can be increased with appropriate vehicles and transdermal permeation enhancers. Stability of the solid dispersion incorporated trandermal gel of Benzoyl Peroxide can be improved with the use of Propylene Glycol. Solid dispersion of Benzoyl Peroxide was prepared in β-cyclodextrin, PEG6000 by kneading method and were characterized for Drug Content. Out of which optimised gel showed the best in-vitro drug release having better dissolution, permeation and stability used for the treatment of Acne.
Foraging and Roosting Behaviour of the Fringe-Lipped Bat, Trachops cirrhosus, on Barro Colorado Island, Panamá

The Neotropical fringe-lipped bat, Trachops cirrhosus, is a generalist predator that hunts frogs and insects by homing in on their mating calls. Although research has examined cognition and prey preferences of bats in captivity, little is known of the foraging or roosting behaviour of this species in the wild. We radio tracked six T. cirrhosus individuals on Barro Colorado Island, Panamá. Bat day roosts were all in hollow cashew trees, Anacardium excelsum, in mixed sex groups of three to five T. cirrhosus individuals, with frequent roost switching. Radio tracked individuals flew an average of 218 ± 227 m from their day roosts to 12.0 ± 10.17 ha foraging areas (50% utilization distribution [UD] kernels = areas where bats spent 50% of their time as estimated from a probability distribution). These 50% UD kernels were less than 10% of their average total range use, but larger than previously reported for T. cirrhosus. Radio tracked individuals overlapped in 50% UD kernel foraging areas by only 2.1 ± 5.9 % on average. Foraging behaviour consisted predominantly of short sally flights of less than one minute, indicating bats were likely perch hunting. Bats were more frequently in flight, and had longer flight durations, at the beginning of the night and just before dawn than throughout the rest of the night. These data provide insight into the foraging behaviour of T. cirrhosus in the wild, that is a species fast becoming a model system of cognition in captivity.
ICF 01012 melanoma imaging and [ 131 I ] ICF 01012 dosimetry allow adapted internal targeted radiotherapy in preclinical melanoma models Running title : Melanoma Imaging and internal targeted radiotherapy

Background: Melanin-targeting radiotracers are interesting tools for imaging and treatment of pigmented melanoma metastases. However variation of the pigment concentration may alter the efficiency of such targeting. Objectives: A clear assessment of both tumor melanin status and dosimetry are therefore prerequisites for internal radiotherapy of disseminated melanoma. Materials & Methods: The melanin tracer ICF01012 was labelled with iodine-123 for melanoma imaging in pigmented murine B16F0 and human SK-Mel 3 melanomas. Results: In vivo imaging showed that the uptake of [ 123 I]ICF01012 to melanomas correlated significantly with melanin content. Schedule treatment of 3 × 25 MBq [ 131 I]ICF01012 significantly reduced SK-Mel 3 tumor growth and significantly increased the median survival in treated mice. For this protocol, the calculated delivered dose was 53.2 Gy. Conclusion: Radio-iodinated ICF01012 is a good candidate for both imaging and therapeutic purposes for patients with metastatic pigmented melanomas.
Advance Directives in Patients Over 60 Years Old: Assessment of Perceived Value and Need For Education in the Outpatient Setting

Background: Advance directives have widely been regarded as playing a pivotal role in end-of-life care for patients. This study sought to evaluate the current value and perspective on advance directives in patients greater than 60 years of age visiting outpatient clinics. Methods: A cross-sectional survey study was performed at four different departmental outpatient clinics at Texas Tech University Health Sciences Center in Amarillo, Texas for patients over the age of 60 years who presented during a three-month time frame. In addition to demographic data, the survey collected data on patients’ perspective on and completion of advance directives. Results: 314 patients completed the survey. Non-Hispanic white patients were significantly more likely than those of other racial or ethnic groups to have an advance directive in place (58.8% vs. 28.8%, p<0.001). Married and widowed patients were more likely to have advance directive than those single or separated (57.2% and 63.1% vs. 30.8% and 35.5%, p=0.002). Those with greater than 12 years of education were also more likely to have an advance directive in place than those with 12 or fewer years of education (59% vs. 48%, p=0.042). Patients who received education from their primary care provider about advance directives were more likely to have an advance directive than those who had not received any education (64.7% vs. 44.9%, p=0.01). Conclusion: Education from physicians about the value of having an advance directive is a powerful intervention that can results in a significant increase in completion of advance directives. Specific demographic groups that could benefit from education about the value of advance directives include patients of different racial or ethnic backgrounds, patients who are single or divorced, and patients with limited education. We recommend that physicians work to initiate discussions about end-of-life care with all patients over 60 years of age.
Efficiency of aggressive and submissive visual displays against environmental motion noise in Jacky dragon (Amphibolurus muricatus)

Despite variations of environmental noise, signals are designed to be effective and conspicuous over an appreciable distance. In particular, visual signals must be perceptible against interference caused by natural elements, such as windblown vegetation. We examined the efficiency of aggressive and submissive displays to elicit behavioural responses from observers in the Jacky dragon (Amphibolurus muricatus) across relative environmental noise. Both displays have been reported to play an important role during social interactions in this species. We conducted two video playback experiments that utilised a high-resolution computer-generated lizard animation to produce social displays that were embedded within simulated windblown vegetation. First, we compared the efficiency a full aggressive display action pattern (comprised of a tail-flick, backward-forward arm wave, and push-up body rock) to a slow arm wave submissive display, against identical background of windblown vegetation. Second, we compared the tail-flick (alerting component) to the slow arm wave across three varying natural conditions, in which the vegetation behind the displays acted as simulated noise: calm, typical, and windy. We found that aggressive displays were more efficient to elicit an observer's response than submissive signals. Furthermore, the tail-flick display is more efficient than submissive displays across a range of natural variation in windblown vegetation movement, but both signals remain efficient in the face of environmental motion noise. Our results suggest that constraints from the environmental background scene play may have a critical role in the evolution of signal design used in Jacky dragon communication.
The Ossification Sequence of Aneides lugubris, with Comments on Heterochrony

Post-hatching ontogeny is described for the skeleton of a large, direct-developing, terrestrial plethodontid salamander, Aneides Iugubris. This species appears to have the most pro- longed ontogeny of the plethodontids. Until the end of the second year of life, osteological ontog- eny is similar to that of other species, but beyond that point major changes occur. Ossification of the long bones continues throughout life and is never completed. Elements such as the pelvic plate ossify continuously, but never completely. Mesopodial elements remain cartilaginous throughout life. The most dramatic changes relate to the feeding system. The anterior part of the skull becomes grotesquely enlarged in the largest specimens, with extensive coossification. Maxillary and dentary teeth decrease in number but increase in size and complexity. Features identified as "supportive adaptations" appear during ontogeny, more so in the feeding than in the locomotory mechanism. Data are interpreted in the framework of recent studies of heterochrony. Salamanders of the family Plethodon- tidae present an unusually good oppor- tunity for investigating the role of devel- opmental modes of evolution in the production of phylogenetic patterns. The family includes a wide array of adaptive morphologies. Several species (in the gen- era Gyrinopkilus, Haideotriton, Eurycea, and Typklornolge) are permanently aquatic and never metamorphose from their essen- tially larval morphology (Dunn, 1926; Wake, 1966). In contrast, over two-thirds have abandoned the aquatic larval stage, have direct terrestrial development, and occupy a vast array of terrestrial habitats, from temperate deciduous forests to des- ert canyons and tropical rain forests. The terrestrial species range from surface- dwelling salamanders to fossorial and arboreal forms. Such developmental modes of evolution as heterochrony have been very important, as is evident from the neoteny of the permanently larval species. However, heterochrony is also of
Role of nutrients in metabolic syndrome: a 2017 update

php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). Nutrition and Dietary Supplements 2018:10 13–26 Nutrition and Dietary Supplements Dovepress
The New Economic Geography

Recently, the 'new economic geography' literature has developed as a theory of the emergence of large agglomerations which relies on increasing returns to scale and transportation costs. This literature builds on diverse intellectual traditions. It combines the insights of traditional regional science with those of modern trade theory and thus attempts to provide an integrative approach to interregional and international trade. The paper surveys this literature and discusses its relation to earlier approaches to similar topics. Copyright 1999 by Blackwell Publishers Ltd
Potential East-West Migration Demographic Structure, Motives and Intentions

This article is based on a large survey which tries to identify the migra- tion potential in the Czech Republic, Hungary, Poland and Slovakia. More than 4,000 persons were asked if they want to migrate, which steps they have undertaken to realise the migration, what their social circumstances are and what they expect of staying and working abroad. One main result was the fact that all scenarios that pre- dict an imminent exodus of people from East and Central Europe are exaggerating the real dimension of East-West migration. The migration potential in Poland, the Czech Republic, Slovakia and Hungary is somewhere between a possible 4 million and a more likely 700,000 persons. The latter figure is less than 1% of the popula- tion over the age of 14. This figure remains, however, higher than the numbers fore- seen by the law for annual immigration to Austria and Germany and higher than the numbers that are thought of as politically acceptable. Furthermore the article gives principal information concerning the demographic and social structure of the people who are willing to leave their country and planning a short or longer stay in Western Europe. 1. Preliminary Remarks Large-scale East-West migration was characteristic of the late 19th and early 20th centu- ries (cf. Fassmann and Munz 1994a). Austria-Hungary, the German Empire and France were the destinations of migrants from East and South-east Europe. With the spread of industrial methods of production from the mid-19th century, with far-reaching improve- ments in public transport and the liberalisation of laws concerning the right of establish- ment, East-West migration reached substantial proportions. The industrial centres of Lorraine, the Ruhr and the Vienna Basin joined the European metropolises of Paris, Ber- lin and Vienna as migration destinations for several hundred thousand people from East and East-Central Europe. Until the Second World War, Berlin was the centre of attraction for Prussians, Silesians, Poles and people from the Baltics, whilst Vienna was for Bohe- mians, Moravians and Jews from Galicia and Bukowina. The second stage of East-West European migration was a direct result of the Sec- ond World War and its consequences for the post-war European order. According to rough estimates 15.4 million people had to leave their former home countries in the years after the war (1944-50); taken alone more than 12 million East and ethnic Germans fled from the former eastern parts of the German Reich and Poland or were expelled from Czechoslovakia. The national borders settled at Yalta and Potsdam affected not only East
Associations between polymorphisms in the myostatin, αA-globin and lactate dehydrogenase B genes and racing performance in homing pigeons

The aim of this study was to investigate the associations between variability in the myostatin, αA-globin and lactate dehydrogenase B genes and racing performance in homing pigeons. The study included 123 animals (60 females and 63 males) participating in racing competitions. The data set used in this study consisted of scores from 17 short (≤ 400 km) and 11 long races (≥ 500 km) (2589 race records in total). Our study is the first study to analyse the associations between polymorphisms in the myostatin, αA-globin and lactate dehydrogenase B genes and racing performance in pigeons. However, no associations were found between the SNPs analysed and the studied traits.
Coupled Inertial Navigation and Flush Air Data Sensing Algorithm for Atmosphere Estimation

This paper describes an algorithm for atmospheric state estimation based on a coupling between inertial navigation and flush air data-sensing pressure measurements. The navigation state is used in the atmospheric estimation algorithm along with the pressure measurements and a model of the surface pressure distribution to estimate the atmosphere using a nonlinear weighted least-squares algorithm. The approach uses a high-fidelity model of atmosphere stored in table-lookup form, along with simplified models propagated along the trajectory within the algorithm to aid the solution. Thus, the method is a reduced-order Kalman filter in which the inertial states are taken from the navigation solution and atmospheric states are estimated in the filter. The algorithm is applied to data from the Mars Science Laboratory entry, descent, and landing from August 2012. Reasonable estimates of the atmosphere are produced by the algorithm. The observability of winds along the trajectory are examined using an index based o.
HAVRILIAK-NEGAMI RESPONSE IN THE FRAMEWORK OF THE CONTINUOUS-TIME RANDOM WALK ∗

We show how to modify the random-walk scenario underlying the classical, exponential relaxation response in order to derive the empirical Havriliak–Negami function, commonly used to fit the dielectric permittivity of complex-material data. The turnover from the exponential Debye to the power-law Havriliak–Negami relaxation response is associated with a new type of a coupled memory continuous-time random walk (CTRW) driving a fractional dynamics.
The Antihypertensive Effect of ASA Lasts Less than 24 Hours

Objectives: Some studies suggest that acetylsalicylic acid (ASA) administered in the evening may have a lowering effect on the blood pressure. The purpose of this study was to measure the effect of the time of ASA administration on blood pressure, markers of arterial stiffness as well as various plasma parameters. Methods and Results: The study included 34 patients (20 men and 14 women) ranging in age from 47 to 82 years. Low-dose ASA (50 - 250 mg/day) was used by all the patients, first in the morning and later in the evening for three months. Home, office and ambulatory blood pressure and pulse wave velocity (PWV) were measured. Compared with the morning administration of ASA, significantly lower office systolic blood pressure (p = 0.017) and significantly higher carotid-femoral PWV (p = 0.010) as well as plasma triglycerides (p = 0.002) were found after the evening administration. There were no statistically significant changes in the average ambulatory blood pressure values, carotid-radial PWV or other parameters measured. However, the time of ASA administration seemed to affect the circadian variation in blood pressure. Conclusions: The results suggest that ASA administration may lower blood pressure, but for less than 24 hours. Our results should be verified by larger, randomized studies.
Data Statements for Natural Language Processing: Toward Mitigating System Bias and Enabling Better Science

In this paper, we propose data statements as a design solution and professional practice for natural language processing technologists, in both research and development. Through the adoption and widespread use of data statements, the field can begin to address critical scientific and ethical issues that result from the use of data from certain populations in the development of technology for other populations. We present a form that data statements can take and explore the implications of adopting them as part of regular practice. We argue that data statements will help alleviate issues related to exclusion and bias in language technology, lead to better precision in claims about how natural language processing research can generalize and thus better engineering results, protect companies from public embarrassment, and ultimately lead to language technology that meets its users in their own preferred linguistic style and furthermore does not misrepresent them to others.
Simultaneous Tolerance Intervals for the Linear Regression Model

In this article, we address the problem of constructing the simultaneous tolerance intervals for linear regression. The suggested method is based on inverting the exact likelihood ratio test (LRT) for testing the simple null hypothesis on all parameters of the linear regression model with normally distributed errors, as proposed in Chvostekova and Witkovský (2009).
Ab initio study of the split silicon-vacancy defect in diamond: Electronic structure and related properties

The split silicon-vacancy (SiV) defect in diamond is an electrically and optically active color center. Recently, it has been shown that this color center is bright and can be detected at the single defect level. In addition, the SiV defect shows a nonzero electronic spin ground state that potentially makes this defect an alternative candidate for quantum optics and metrology applications beside the well-known nitrogen-vacancy color center in diamond. However, the electronic structure of the defect, the nature of optical excitations and other related properties are not well understood. Here we present advanced ab initio study on SiV defect in diamond. We determine the formation energies, charge transition levels, and the nature of excitations of the defect. Our study unravels the origin of the dark or shelving state for the negatively charged SiV defect associated with the 1.68-eV photoluminescence center.