Miracle-dz/UniFAR-FTUs huggingface dataset:
Clinical, socio‐demographic and psychological characteristics in individuals with persistent psychotic experiences with and without a “need for care”

Individuals reporting persistent psychotic experiences (PEs) in the general population, but without a “need for care”, are a unique group of particular importance in identifying risk and protective factors for psychosis. We compared people with persistent PEs and no “need for care” (non‐clinical, N=92) with patients diagnosed with a psychotic disorder (clinical, N=84) and controls without PEs (N=83), in terms of their phenomenological, socio‐demographic and psychological features. The 259 participants were recruited from one urban and one rural area in the UK, as part of the UNIQUE (Unusual Experiences Enquiry) study. Results showed that the non‐clinical group experienced hallucinations in all modalities as well as first‐rank symptoms, with an earlier age of onset than in the clinical group. Somatic/tactile hallucinations were more frequent than in the clinical group, while commenting and conversing voices were rare. Participants in the non‐clinical group were differentiated from their clinical counterparts by being less paranoid and deluded, apart from ideas of reference, and having fewer cognitive difficulties and negative symptoms. Unlike the clinical group, they were characterized neither by low psychosocial functioning nor by social adversity. However, childhood trauma featured in both groups. They were similar to the controls in psychological characteristics: they did not report current emotional problems, had intact self‐esteem, displayed healthy schemas about the self and others, showed high life satisfaction and well‐being, and high mindfulness. These findings support biopsychosocial models postulating that environmental and psychological factors interact with biological processes in the aetiology of psychosis. While some PEs may be more malign than others, lower levels of social and environmental adversity, combined with protective factors such as intact IQ, spirituality, and psychological and emotional well‐being, may reduce the likelihood of persistent PEs leading to pathological outcomes. Future research should focus on protective factors and determinants of well‐being in the context of PEs, rather than exclusively on risk factors and biomarkers of disease states.
The Commitment-Trust Theory of Relationship Marketing

Relationship marketing—establishing, developing, and maintaining successful relational exchanges—constitutes a major shift in marketing theory and practice. After conceptualizing relationship marketing and discussing its ten forms, the authors (1) theorize that successful relationship marketing requires relationship commitment and trust, (2) model relationship commitment and trust as key mediating variables, (3) test this key mediating variable model using data from automobile tire retailers, and (4) compare their model with a rival that does not allow relationship commitment and trust to function as mediating variables. Given the favorable test results for the key mediating variable model, suggestions for further explicating and testing it are offered.
Sensitivity of synaptic GABAA receptors to allosteric modulators in hippocampal oriens‐alveus interneurons

GABAA receptors are heteropentamers that are heterogeneously distributed at different synapses in the central nervous system. Although the modulation of GABAA receptors received much attention in hippocampal pyramidal cells, information is scarce regarding the pharmacology of these receptors in inhibitory interneurons. We investigated the pharmacological properties of GABAA‐mediated miniature inhibitory postsynaptic currents (mIPSCs) using whole‐cell voltage clamp recordings in two morphologically identified types of hippocampal CA1 interneurons, horizontal and vertical cells of stratum oriens‐alveus. The negative modulators zinc (200 μM) and furosemide (600 μM) significantly decreased the amplitude of mIPSCs. Benzodiazepine agonists also produced significant effects: 10 μM zolpidem increased the amplitude, rise time, and decay time constant (decay τ) of mIPSCs, whereas 10 μM flunitrazepam affected similarly the amplitude and decay τ, but not the rise time. The neurosteroid allopregnanolone (10 μM) prolonged the decay τ of mIPSCs. Since these modulators act on different GABAA receptor subunits, this pharmacological profile suggests that GABAA receptors at spontaneously active inhibitory synapses onto vertical and horizontal interneurons are heterogeneous and formed by co‐assembly of different combinations of subunits (α1–5β1–3γ1–3). Furthermore, these synaptic GABAA receptors appear in large part pharmacologically similar to those of pyramidal cells. Synapse 41:29–39, 2001. © 2001 Wiley‐Liss, Inc.
Service quality in the banking sector in an emerging economy: a consumer survey

Reports on the results and managerial implications of a Turkish study which investigated relationships between service quality, and customer satisfaction, complaint behaviour and commitment. Concludes that the ultimate success of any service quality programme implemented by a bank can only be gauged by creation and retention of satisfied customers. The role of customer‐contact personnel in the attainment of these goals is of paramount importance. Therefore, in their efforts to deliver high quality services to their external publics (i.e. clients), banks should not ignore the specific needs of their internal publics, notably their customer‐contact employees.
Investments and Capital Markets Imperfections, Identification Issues: A Survey

If financial markets are perfect, the choice of the sources of finance does not influence investment decisions. However, financial markets are considered to be far from perfect. This review concentrates on the role of information asymmetry in determining real investment decisions. Despite the theoretical plausibility of a relationship between capital markets imperfections and real investments, the empirical literature has found it difficult to identify this channel. Overall, more research is needed to identify method which will not be subject to critiques related to the use of cash-flow in the investment equation and will be based on the data that are relatively available across countries and over time.
Feedlot Performance Of Dromedary Camel (CAMELUS DROMEDARIUS) Calves fed Different Dietary Regimes

The aim of the present study was to evaluate the feeding performance of Sudanese dromedary camel calves kept under controlled management systems and fed three different dietary regimes. It was also aimed to compare the body weight obtained by using direct weighing bridge and the body weight obtained by using certain body dimensions. The study was carried out at the Animal Research Unit, College of Veterinary Medicine and Animal Production, Khartoum North (Kuku). Twelve growing dromedary male camels were used in the 70 days study trial. The average initial body weight of the calves was 175.75 ± 0.25 kg. The calves were randomly divided into 3 groups, of 4 animals each. The calves in each group were randomly allotted into a separate iso-caloric and iso-nitrogenous dietary treatment. The fattening performance of experimental camels was significantly (P<0.05) affected by dietary treatments. Dry matter (DM) intake, average daily weight gain and feed conversion ratio were significantly (P<0.05) different among dietary treatments. Kenana feed (complete fattening pellets) tended to be superior for daily weight gain (0.815kg), daily DM intake (4.35kg ) and final live body weight (233.28kg). Camels fed diet of cottonseed cake (CSC) had lowes (P<0.05) feed intake (3.99kg) and daily gain (0.591kg) with poor feed conversion ratio (9.98). Prediction of body weight from body measurements has been proved in this study. The results showed that there was a high correlation (p<0.0001) between body weight obtained by direct weighing using a weigh bridge and the body weight obtained using certain body measurements.
The Effects of Strategic Orientations on Technology- and Market-Based Breakthrough Innovations

Does market orientation impede breakthrough innovation? To date, researchers have presented opposing arguments with respect to this important issue. To address this controversy, the authors conceptualize and empirically test a model that links different types of strategic orientations and market forces, through organizational learning, to breakthrough innovations and firm performance. The results show that a market orientation facilitates innovations that use advanced technology and offer greater benefits to mainstream customers (i.e., technology-based innovations) but inhibits innovations that target emerging market segments (i.e., market-based innovations). A technology orientation is beneficial to technology-based innovations but has no impact on market-based innovations, and an entrepreneurial orientation facilitates both types of breakthroughs. Different market forces (demand uncertainty, technology turbulence, and competitive intensity) exert significant influence on technology- and market-based innovations, and these two types of innovations affect firm performance differently. The results have significant implications for firm strategies to facilitate product innovations and achieve competitive advantages.
Guest editorial: Retailing for communities: issues of inclusion and exclusion

Local shopping is a topic that has been neglected for many years by both retail researchers and policy makers. However, in recent years it has come on to the agenda again, mainly because a number of government policy areas – including social exclusion, regeneration and sector competitiveness – have recognised the vital community role played by small shops, and the problems of maintaining their vitality and viability. Within that context, introduces the special issue of IJRDM which presents a number of papers on the general theme of retailing for communities that were given at the CIRM Conference held in Manchester on 13 September 2002. They fall into three main groups: local shopping areas; business strategy and operations; and, learning, training and support for small retailers. The papers illustrate the diversity of research that needs to be undertaken in this area, and there are close parallels with work being undertaken in other management and social science disciplines.
High prevalence of extra-genital chlamydial or gonococcal infections among men who have sex with men and transgender women in Lima, Peru

Chlamydia trachomatis and Neisseria gonorrhoeae are among the most common sexually transmitted bacterial infections in the world. Data are limited, however, on the burden of extra-genital chlamydial and gonococcal infections among men who have sex with men and transgender women in Lima, Peru. Data were gathered from self-collected anal or pharyngeal swabs from participants in Lima, Peru, and analyzed via cross-sectional methods. Prevalence ratios for the association between extra-genital infection with socio-demographic and sexual behaviors were determined. Overall, 127 (32.8%) participants had anal or pharyngeal infections. On multivariate modeling, anal infection was positively associated with practicing both receptive and insertive anal sex, when compared to insertive alone (PR = 2.49; 95% CI = 1.32–4.71), and negatively associated with any antibiotic use in the prior three months (PR = 0.60; 95% CI = 0.39–0.91). Pharyngeal infection was negatively associated with age greater than 30 years compared to 18–30 years (PR = 0.54; 95% CI = 0.30–0.96), and positively associated with gender identity of transgender women (PR = 2.12; 95% CI = 1.20–3.73). This study demonstrates considerable burden of extra-genital chlamydial and gonococcal infections among men who have sex with men and transgender women in Lima, Peru.
E-commerce information systems (ECIS) in a relational service context

There is a general scarcity of models and frameworks for evaluating e-commerce information systems (ECIS) in a relational service context. Traditional theories and models in the fields of the information systems and marketing can be extended to address this issue. Particularly, we believe that deeper theoretical developments are needed to re-examine the ECIS quality concept in the online context as well as its impact on customer satisfaction in the relational service area. Through theoretical discussions of how system quality, information quality, and service quality are related to each other and to customer satisfaction, this research applies and extends IS success models, as well as SERVQUAL framework to the internet service environment. An ECIS quality (ECISQ) model is proposed to consider the unique characteristics of the internet and the service domain.
Safety and Pharmacokinetics of Sirolimus-eluting Stents in the Canine Cerebral Vasculature: 180 Day Assessment

OBJECTIVE:We evaluated local and systemic pharmacokinetics and pharmacodynamics of sirolimus-eluting stents (SES) in canine cerebral vessels. METHODS:SES (1.5 × 8 mm, 79 &mgr;g/479 &mgr;g sirolimus) and control stents (1.5 × 8 mm stainless steel with or without polymer) were implanted in canine basilar and ventral spinal arteries. Animals were sacrificed for local pharmacokinetic (36 animals at 1, 3, 8, 30, 90, 180 days) and pharmacodynamic (60 animals at 3, 30, 90, 180 days) assessment. RESULTS:Postrecovery adverse clinical events were not serious, requiring no unscheduled treatment. Histologically, brain and spinal cord sections revealed scattered microinfarcts and minimal gliosis consistent with postprocedure changes in all four stent-treatment groups. All stented vessels at all time points demonstrated good luminal patency with low injury and inflammation scores and no thrombosis of either stented or branch arteries. Endothelialization was complete in all stent groups by 30 days. Intimal smooth muscle cell scores were reduced in both SES groups at 30, 90, and 180 days. Systemic sirolimus levels peaked between 1 and 7 hours postimplant (maximum concentration, 1.2 ± 1.47, 79 &mgr;g; 4.5 ± 1.23 ng/ml, 479 &mgr;g), then declined rapidly to 1 ng/ml or less by 96 hours. Peak local tissue sirolimus levels were 41.5 ng/mg (79 &mgr;g) and 65 ng/mg (479 &mgr;g). CONCLUSION:SES in canine cerebral vessels were associated with good luminal patency to 180 days, with complete endothelialization and no evidence of acute thrombosis. This model has shown that SES deployed within the brain do not cause neurotoxicity during a 180-day time course, even when exaggerated doses are used. The findings support the contention that SES are safe to use and maintain patency in cerebral vessels.
Deciphering the Physalis fl oridana Double-Layered-Lantern 1 Mutant Provides Insights into Functional Divergence of the GLOBOSA Duplicates within the Solanaceae 1 [ C ] [ W ]

Physalis spp. develop the “Chinese lantern” trait, also known as inflated calyx syndrome, that is a morphological novelty. Here, we identified the double-layered-lantern1 (doll1) mutant, a recessive and monofactorial mutation, in Physalis floridana; its corolla and androecium were transformed into the calyx and gynoecium, respectively. Two GLOBOSA-like MADS-box paralogous genes PFGLO1 and PFGLO2 were found in Physalis floridana, while the mutated phenotype was cosegregated with a large deletion harboring PFGLO1 and was complemented by the PFGLO1 genomic locus in transgenic plants, and severe PFGLO1 knockdowns phenocopied doll1. Thus, DOLL1 encodes the PFGLO1 protein and plays a primary role in determining corolla and androecium identity. However, specific PFGLO2 silencing showed no homeotic variation but rather affected pollen maturation. The two genes featured identical floral expression domains, but the encoding proteins shared 67% identity in sequences. PFGLO1 was localized in the nucleus when expressed in combination with a DEFICIENS homolog from Physalis floridana, whereas PFGLO2 was imported to the nucleus on its own. The two proteins were further found to have evolved different interacting partners and regulatory patterns, supporting the hypothesis that PFGLO2 is functionally separated from organ identity. Such a divergent pattern of duplicated GLO genes is unusual within the Solanaceae. Moreover, the phenotypes of the PFGLO1PFGLO2 double silencing mutants suggested that PFGLO2, through genetically interacting with PFGLO1, also exerts a role in the control of organ number and tip development of the second floral whorl. Our results, therefore, shed new light on the functional evolution of the duplicated GLO genes.
Differentiating Entrepreneurs from Small Business Owners: A Conceptualization

The literature of small business and entrepreneurship is explored. It is established that, although there is an overlap between entrepreneurial firms and small business firms, they are different entities. Using the 1934 work of Schumpeter and recognizing the additions to the field of current writers, a conceptual framework is established for the differentiation of entrepreneurs from small business owners.
STELLAR AND PLANETARY PROPERTIES OF K2 CAMPAIGN 1 CANDIDATES AND VALIDATION OF 17 PLANETS, INCLUDING A PLANET RECEIVING EARTH-LIKE INSOLATION

The extended Kepler mission, K2, is now providing photometry of new fields every three months in a search for transiting planets. In a recent study, Foreman-Mackey and collaborators presented a list of 36 planet candidates orbiting 31 stars in K2 Campaign 1. In this contribution, we present stellar and planetary properties for all systems. We combine ground-based seeing-limited survey data and adaptive optics imaging with an automated transit analysis scheme to validate 21 candidates as planets, 17 for the first time, and identify 6 candidates as likely false positives. Of particular interest is K2-18 (EPIC 201912552), a bright (K = 8.9) M2.8 dwarf hosting a 2.23 ± 0.25 R ⨁ ? > planet with T eq = 272 ± 15 ? > K and an orbital period of 33 days. We also present two new open-source software packages which enable this analysis. The first, isochrones, is a flexible tool for fitting theoretical stellar models to observational data to determine stellar properties using a nested sampling scheme to capture the multimodal nature of the posterior distributions of the physical parameters of stars that may plausibly be evolved. The second is vespa, a new general-purpose procedure to calculate false positive probabilities and statistically validate transiting exoplanets.
Social support provided to caregivers of children with cerebral palsy.

OBJECTIVE To describe the perception of caregivers of children with cerebral palsy (CP) concerning social support received and to verify how the characteristics of the children (i.e. type of CP and severity of motor impairment) and those of their caregivers (i.e. age, level of education, occupation, income and number of children) are significantly related to this perception. METHOD A total of 50 children with CP aged between 3 and 12 years and their respective caregivers participated in this study. Children were grouped in terms of type of CP and according to the severity of motor impairment through the Gross Motor Function Classification System (GMFCS). The Social Support Questionnaire (SSQ) was used to evaluate the perception of caregivers concerning the social support they receive (number of people offering support - SSQ-N index, and level of satisfaction concerning such support - SSQ-S index). RESULTS The caregivers reported receiving support from a mean of 1.67 people. Core and extended family members (i.e. husband, mother, siblings) and friends are the most common providers of support. In regard to level of satisfaction, caregivers considered the support they received to be positive, obtaining a mean of 5.52 out of a total of six points. Children's and caregivers' characteristics were not significantly related to the SSQ-N and SSQ-S indexes. CONCLUSION Family members are the caregivers' primary source of social support and caregivers reported being satisfied with the support they received.
Impact of Demographic Factors on Consumer Behaviour - A Consumer Behaviour Survey in Himachal Pradesh

Consumer behaviour doesn't remain the same or constant in every situation it changes time to time. There are various factors which affects consumer behaviour. As the change comes in these factors, consumer behaviour also changes. The demographic factors which affect consumer behavior are: (1) age (2) sex (3) marital status (4) income (5) family background (6) education (7) occupation (8) family size (9) geographic factors (10) psychological factors. In this grim battle for snatching maximum share of market, only those producers are destined to emerge victorious who will be able to read the pulse of the buyers. And this is here, where buyer behaviour has a very important role to play. There are so many demographic factors like age, sex, income, occupation, education, marital status and family background which affects the behaviour of consumers. Here an at-tempt has been made that how and to what extent these factors affects the behaviour of consumers. It is quite necessary for the manufacturers of four-wheeler to know the behaviour of consumers. So, that they can increase their sales and capture the maximum share of the market. In this research paper an attempt has been made to know the affect of demographic factors on consumer behavior.
Spontaneous recovery of superhydrophobicity on nanotextured surfaces

Significance Due to its aversion to the hydrophobic surface texture, a water droplet makes minimal contact with, and readily rolls off of, a superhydrophobic surface, conferring it with beneficial properties such as water repellency and self-cleaning. However, the surface texture can readily wet in response to conditions such as elevated pressures, leading to a breakdown of superhydrophobicity that is widely believed to be irreversible. By using specialized molecular simulations to study surfaces with nanoscale texture, here we find that the dewetting of the surface texture is strongly influenced by water density fluctuations. Furthermore, an understanding of the dewetting pathways allows us to design novel surface textures on which fluctuations can facilitate a spontaneous recovery of superhydrophobicity. Rough or textured hydrophobic surfaces are dubbed “superhydrophobic” due to their numerous desirable properties, such as water repellency and interfacial slip. Superhydrophobicity stems from an aversion of water for the hydrophobic surface texture, so that a water droplet in the superhydrophobic “Cassie state” contacts only the tips of the rough surface. However, superhydrophobicity is remarkably fragile and can break down due to the wetting of the surface texture to yield the “Wenzel state” under various conditions, such as elevated pressures or droplet impact. Moreover, due to large energetic barriers that impede the reverse transition (dewetting), this breakdown in superhydrophobicity is widely believed to be irreversible. Using molecular simulations in conjunction with enhanced sampling techniques, here we show that on surfaces with nanoscale texture, water density fluctuations can lead to a reduction in the free energetic barriers to dewetting by circumventing the classical dewetting pathways. In particular, the fluctuation-mediated dewetting pathway involves a number of transitions between distinct dewetted morphologies, with each transition lowering the resistance to dewetting. Importantly, an understanding of the mechanistic pathways to dewetting and their dependence on pressure allows us to augment the surface texture design, so that the barriers to dewetting are eliminated altogether and the Wenzel state becomes unstable at ambient conditions. Such robust surfaces, which defy classical expectations and can spontaneously recover their superhydrophobicity, could have widespread importance, from underwater operation to phase-change heat transfer applications.