Miracle-dz/UniFAR-FTUs huggingface dataset:
Shaping Ability of ProTaper Next, WaveOne, and Reciproc in Simulated Root Canals.

INTRODUCTION The study aimed to compare the shaping and preservation of the original curvature of simulated curved root canals using the following instruments: Reciproc (Rcp), WaveOne (Wo), and the ProTaper Next system (Ptn). MATERIALS AND METHODS A total of 45 resin blocks with simulated curved root canals were divided into three groups (n = 15), prepared using the Rcp (R25), Wo (25/0.8), and Ptn (X2) instruments. Standardized photographs were taken before and after canal instrumentation. After the superimposition of the images, the amount of resin removed from the curvature's inner and outer walls was measured at six apical levels, at intervals of 1 mm. The canals' angles of curvature before and after instrumentation were subtracted. RESULTS There were no significant differences between the instruments in terms of the total amount of resin removed of the inner or outer walls of the apical curvature (p > 0.05). The Rcp instruments provided the best resin removed ratios between the walls. The means of the change in angle were as follows: Wo = 2.15°, Ptn = 0.92°, and Rcp = 0.21°. WaveOne caused significantly higher deviations than Rcp. CONCLUSION All of the instruments demonstrated a tendency to straighten the simulated root canal. Instruments that use rotary movement achieved an effect similar to that of the reciprocating instruments in relation to change in angle. CLINICAL SIGNIFICANCE Deviations from the original shape of the root canal could have a negative impact on the quality of a filling and consequently on the success of the endodontic treatment.
Kinetic Simulations of SPT and HEMP Thrusters Including the Near-Field Plume Region

The particle-in-cell (PIC) method is used to study two different ion thruster concepts-stationary plasma thrusters (SPTs) and high-efficiency multistage plasma thrusters (HEMP-Ts)-in particular, the plasma properties in the discharge chamber due to the different magnetic field configurations. Special attention is paid to the simulation of plasma particle fluxes on the thrusters' channel surfaces. In both cases, PIC proves itself as a powerful tool, delivering important insight into the basic physics of the different thruster concepts. The simulations demonstrated that the new HEMP-T concept allows for a high thermal efficiency due to both minimal energy dissipation and high acceleration efficiency. In the HEMP-T, the plasma contact to the wall is limited only to very small areas of the magnetic field cusps, which results in small ion energy flux to the thruster channel surface. The erosion yields for dielectric discharge channel walls of SPT and HEMP-Ts were calculated with the binary collision code SDTrimSP. For HEMP, thruster simulations have shown that there is no erosion inside the dielectric discharge channel.
A bioturbation classification of European marine infaunal invertebrates

Bioturbation, the biogenic modification of sediments through particle reworking and burrow ventilation, is a key mediator of many important geochemical processes in marine systems. In situ quantification of bioturbation can be achieved in a myriad of ways, requiring expert knowledge, technology, and resources not always available, and not feasible in some settings. Where dedicated research programmes do not exist, a practical alternative is the adoption of a trait-based approach to estimate community bioturbation potential (BPc). This index can be calculated from inventories of species, abundance and biomass data (routinely available for many systems), and a functional classification of organism traits associated with sediment mixing (less available). Presently, however, there is no agreed standard categorization for the reworking mode and mobility of benthic species. Based on information from the literature and expert opinion, we provide a functional classification for 1033 benthic invertebrate species from the northwest European continental shelf, as a tool to enable the standardized calculation of BPc in the region. Future uses of this classification table will increase the comparability and utility of large-scale assessments of ecosystem processes and functioning influenced by bioturbation (e.g., to support legislation). The key strengths, assumptions, and limitations of BPc as a metric are critically reviewed, offering guidelines for its calculation and application.
Moral Distress Among School Nurses

School nurses are well positioned to provide care to a diverse population of school-age children, but their role and work environment can present a variety of moral dilemmas leading to moral distress. The purpose of this study is to identify the moral distress level that exists in school nurses and to describe its relationship to common moral dilemmas and school nurse characteristics. Data were collected through face-to-face attendance at school nurse meetings in North Carolina where 307 school nurses participated in the survey. Moral distress was measured using the moral distress thermometer, and common moral dilemmas were identified using a researcher developed questionnaire. Almost all of the school nurses (97.3%) experienced some degree of moral distress. Each of the common moral dilemmas was positively correlated with moral distress levels. The findings suggest that many of the common moral dilemmas experienced by school nurses are strongly related to moral distress.
Ontogenetic changes in the bathypelagic distribution of European perch fry Perca fluviatilis monitored by hydroacoustic methods

The behaviour of bathypelagic perch fry (BPF) was monitored during 21 May, 24 June, 8 August and 5 September 1996 along the longitudinal profile of Římov reservoir (Czech Republic), using acoustic methods (SIMRAD EY 500 echosounder, elliptical split-beam transducer, Sonar5 postprocessing software). In May, the BPF layer comprised a mass of solitary perch larvae at an abundance of over 31,000 ind. ha−1. In contrast, in June, the BPF layer consisted almost exclusively of shoaling individuals. The abundance of BPF increased up to 166,000 ind. ha−1. Similary, in August, fish in shoals prevailed in the BPF layer but the abundance dropped to less than 3,000 ind. ha−1. In September, the BPF layer consisted of both individuals and small groups of fish. At this time the abundance of BPF slightly increased to almost 5,000 ind. ha−1. Individual parameters describing the BPF layer, depth of the main layer, abundance of BPF in the main layer and thickness of the whole layer, differed significantly among months. The negligible abundance of potential predators below the thermocline, both in June and in August (exclusively adult perch), suggests that the BPF shoals were more likely to be created as a result of a social need rather than as a defense against predators. During similar surveys carried out prior to (25 April, 5 May, 7 May, 12 May, 15 May) and after this period (3 October, 7 November, 2 December), the BPF layer was not recorded.
The progression of maternal RSV antibodies in the offspring

The concentrations of maternal anti-RSV IgG antibodies were followed in 49 healthy newborns over the first six months of life. At birth, 41 mothers (83%) tested positive for anti-RSV IgG and all of their babies carried maternal anti-RSV IgG. Anti-RSV IgG positivity dropped to 73% at 1 month, 6% at 3 months, and 2% at 6 months. Between 3 and 6 months, 8% did acquire RSV infection, half of them as acute bronchiolitis and half as non-specific respiratory infection. All of the patients who acquired clinical RSV disease had an antibody concentration of <20 RU/ml which may be the cut off value for protection.
Molecular and Phenotypic Analysis of the CS54 Island of Salmonella enterica Serotype Typhimurium: Identification of Intestinal Colonization and Persistence Determinants

ABSTRACT The shdA gene is carried on a 25-kb genetic island at centisome 54 (CS54 island) of the Salmonella enterica serotype Typhimurium chromosome. In addition to shdA, the CS54 island of Salmonella serotype Typhimurium strain LT2 contains four open reading frames designated ratA, ratB, sivI, and sivH. DNA hybridization analysis revealed that the CS54 island is comprised of two regions with distinct phylogenetic distribution within the genus Salmonella. Homologues of shdA and ratB were detected only in serotypes of Salmonella enterica subsp. I. In contrast, sequences hybridizing with ratA, sivI, and sivH were present in S. enterica subsp. II and S. bongori in addition to S. enterica subsp. I. Deletion of the ratA and sivI genes did not alter the ability of Salmonella serotype Typhimurium to colonize the organs of mice. Insertional inactivation of the sivH gene resulted in defective colonization of the Peyer's patches of the terminal ileum but normal colonization of the cecum, mesenteric lymph nodes, and spleen. Deletion of the shdA gene resulted in decreased colonization of the cecum and Peyer's patches of the terminal ileum and colonization to a lesser degree in the mesenteric lymph nodes and spleen 5 days post-oral inoculation of mice. A strain containing a deletion in the ratB gene exhibited a defect for the colonization of the cecum but not of the Peyer's patches, mesenteric lymph nodes, and spleen. The shdA and ratB deletion strains exhibited a shedding defect in mice, whereas the sivH deletion strain was shed at numbers similar to the wild type. These data suggest that colonization of the murine cecum is required for efficient fecal shedding in mice.
Hyperemesis Gravidarum and the Sex of the Offspring

Studies have suggested that offspring of women hospitalized for hyperemesis gravidarum have a different sex ratio than those of women without this diagnosis, but little is known of the potential association between fetal gender and variables such as severity of hyperemesis, gestational trimester, and maternal age. Our findings provide evidence that pregnant women with a diagnosis of hyperemesis gravidarum in the first trimester give birth to a higher proportion of female newborns than do all mothers, regardless of whether they are hospitalized.
Erectile function and sexual satisfaction before and after penile prosthesis implantation in radical prostatectomy patients: a comparison with patients with vasculogenic erectile dysfunction.

INTRODUCTION Patients with erectile dysfunction (ED) after radical prostatectomy (RP) may benefit from penile prosthesis (PP) implantation after failure of less invasive treatments. Aim. To assess surgical outcomes and satisfaction after PP implantation in RP patients and compare the results with those in patients with vasculogenic ED (controls). METHODS A database of 415 consecutive PPs (January 1996-December 2008) was used to collate data on preimplantation ED treatments, surgical complications, satisfaction, and International Index of Erectile Function (IIEF) scores before and 3 months after implantation. The results for 90 post-RP implants (79 primary, 11 secondary) and 131 implants for vasculogenic ED were compared. MAIN OUTCOME MEASURES The main outcome measures of this study are intra- and postoperative complications and IIEF domain scores. RESULTS Mean follow-up of RP patients was 37.6 ± 26.8 months. Mean interval between RP and PP implantation was 31.5 ± 28.7 months. Nearly all primary implants (96.2%) were inflatable (3-piece, 70.1%; 2-piece, 24.1%). There was no significant difference between groups in terms of rates of infection (1.1%), mechanical failure (3.3%), and other surgical complications requiring revision surgery (migration, auto-inflation) (4.4%). For primary implants, the mean preimplantation IIEF score (all items) was significantly lower in RP patients than in controls (14.7 ± 5.9 vs. 22.6 ± 10.8, P = 0.003), chiefly because of significantly lower scores for erectile function, intercourse satisfaction, and orgasmic function. After PP implantation in RP patients, the scores for all domains improved, but the total score remained significantly lower than in controls (63.1 ± 7.0 vs. 68.5 ± 6.9, P = 0.005). The orgasmic function score was significantly lower (P < 0.001). Overall satisfaction rate was 86.1% in RP patients and 90.7% in controls (P = 0.3). CONCLUSIONS PP implantation after RP is associated with low morbidity and high satisfaction. It improves the scores for all IIEF domains and, in particular, erectile function. Fibrosis of the retropubic space may require a second incision for reservoir placement or implantation of a 2-piece PP.
Erythropoietin-mediated expression of placenta growth factor is regulated via activation of hypoxia-inducible factor-1α and post-transcriptionally by miR-214 in sickle cell disease.

Placental growth factor (PlGF) plays an important role in various pathological conditions and diseases such as inflammation, cancer, atherosclerosis and sickle cell disease (SCD). Abnormally high PlGF levels in SCD patients are associated with increased inflammation and pulmonary hypertension (PHT) and reactive airway disease; however, the transcriptional and post-transcriptional mechanisms regulating PlGF expression are not well defined. Herein, we show that treatment of human erythroid cells and colony forming units with erythropoietin (EPO) increased PlGF expression. Our studies showed EPO-mediated activation of HIF-1α led to subsequent binding of HIF-1α to hypoxia response elements (HREs) within the PlGF promoter, as demonstrated by luciferase transcription reporter assays and ChIP analysis of the endogenous gene. Additionally, we showed miR-214 post-transcriptionally regulated the expression of PlGF as demonstrated by luciferase reporter assays using wild-type (wt) and mutant PlGF-3'-UTR constructs. Furthermore, synthesis of miR-214, located in an intron of DNM3 (dynamin 3), was transcriptionally regulated by transcription factors, peroxisome proliferator-activated receptor-α (PPARα) and hypoxia-inducible factor-1α (HIF-1α). These results were corroborated in vivo wherein plasma from SCD patients and lung tissues from sickle mice showed an inverse correlation between PlGF and miR-214 levels. Finally, we observed that miR-214 expression could be induced by fenofibrate, a Food and Drug Administration (FDA) approved PPARα agonist, thus revealing a potential therapeutic approach for reduction in PlGF levels by increasing miR-214 transcription. This strategy has potential clinical implications for several pathological conditions including SCD.
Examining institutional career preparation: student perceptions of their workplace readiness and the role of the university in student career development

xiii Chapter One: Introduction . 1 Background of the Problem . 6 Problem Statement . 11 Purpose of Research . 11 Research Questions . 12 Research Design . 12 Assumptions and Delimitations . 13 Conceptual Framework . 15 Definitions and Key Terms . 17 Significance of the Study . 19 Chapter Summary . 21 Chapter Two: Review of the Literature . 22 Workplace Readiness . 22 Perceptions and Attitudes towards Workplace Readiness . 30 Employment & Underemployment . 37 Gainful Employment . 40 Career Services in Higher Education . 45 Chapter Summary . 57 Chapter Three: Methods . 59 Research Design & Role of the Researcher . 60 Sources of Data . 62 Sampling Method and Sample Size . 63 Data Collection Strategies and Procedures . 63 Tools/Instruments Used . 64 Procedures . 67 Ethical Considerations . 67
East Asian welfare regime: obsolete ideal-type or diversified reality

ABSTRACT The paper asks if East Asian welfare regimes are still productivist and Confucian? And, have they developed public care policies? The literature is split on the first question but (mostly) confirmative on the second. Care has to a large, but insufficient extent, been rolled out in the region. Political science studies tend to conclude that the region has left the old legacies behind and are now welfare states comparable to European states including them either in the conservative type (e.g. Japan), the liberal type (e.g. Korea) or even as a tendency in the Nordic type (e.g. China), while studies focusing on outcomes or causal links tend to suggest that legacies prevail, but there is (nearly) consensus that Confucianism exercises great influence in the whole region.
Tumor HLA‐DR expression linked to early intrahepatic recurrence of hepatocellular carcinoma

The outcome of patients with hepatocellular carcinoma (HCC) remains poor because of the high frequency of intrahepatic recurrence (IHR), particularly early IHR within 1 year of hepatectomy. To search for genes involved in early IHR, we performed DNA microarray analysis in a training set of 33 HCCs and selected 46 genes linked to early IHR from approximately 6,000 genes by means of a supervised learning method. Gene selection was validated by a false discovery rate of 0.37%. The 46 genes included many immune response‐related genes, which were all downregulated in HCCs with early IHR. Four of these genes (HLA‐DRA, HLA‐DRB1, HLA‐DG and HLA‐DQA), encoding MHC class II antigens, were coordinately downregulated in HCCs with early IHR compared to levels in HCCs with nonrecurrence. A cluster analysis reproduced expression patterns of the 4 MHC class II genes in 27 blinded HCC samples. To localize the major site of production of HLA‐DR protein in the tumor, we used 50 frozen specimens from 50 HCCs. Immunofluorescence staining showed that HLA‐DR protein levels in tumor cells, but not in stromal cells, were associated with the transcription levels of HLA‐DRA determined by both DNA microarray analysis and real‐time quantitative reverse transcription‐PCR. Univariate analysis showed that tumor HLA‐DR protein expression, pTNM stage and venous invasion were associated with early IHR. Multivariate analysis showed that tumor HLA‐DR protein expression was one of the independent risk factors for early IHR, suggesting HLA‐DR protein potential as a biomarker and a molecular target for therapeutic intervention. © 2005 Wiley‐Liss, Inc.
The Effect of Surprise on Customer Satisfaction: The Moderating Role of Status Consumption

This study focused on the moderating role of different levels of status consumption on surprise (independent variable) and customer satisfaction (dependent variable). Two types of products – utilitarian and hedonic – were introduced unexpectedly to elicit surprise from participants. Three control variables were included: age, pre-consumption mood, and attitude toward the product. The experiment was manipulated with hypothetical scenarios in a 2 × 2 factorial design in a hotel setting. The sample population comprised 184 executive MBA students in northern Taiwan. Data from 176 of the participants were analyzed using the ANCOVA method. The results indicated that both utilitarian and hedonic products, given as a surprise, were effective in satisfying customers. The results showed, however, that customers with high levels of status consumption preferred hedonic products, whereas customers with low levels of status consumption preferred utilitarian products. Keywords: Surprise, status consumption, satisfaction
The immediate effect of dry needling on multifidus muscles' function in healthy individuals.

BACKGROUND Dry needling of muscles is mainly used for the management of pain in musculoskeletal disorders. Yet, the association between dry needling and motor performance of muscles is still unclear. OBJECTIVE To investigate the immediate effect of dry needling on lumbar multifidus muscles' function in healthy subjects. METHODS Twenty-eight volunteers were divided randomly into: study group (13 subjects) and control group (15 subjects) who underwent no intervention. Study group received dry needling to the lumbar multifidus muscles using a deep insertion technique with 4 needles (2 on each side of the spine). The needles were left in situ for 10 minutes. Ultrasound imaging was used to measure multifidus muscles' thickness, pre and post-procedure during rest in a prone position and during contralateral active straight leg extension. RESULTS Significant difference was found in the percentage of change of muscle activation post needling between groups on the right side at level L4-5. A slight increase in the percentage of muscle activity, post procedure was observed in the dry needling group compared with the control group, although not significant in other segments examined. CONCLUSION An improvement of back muscle function following dry needling procedure in healthy individuals was found. This implies that dry needling might stimulate motor nerve fibers and as such increase muscle activity.
When revenues are not revenues: the influence of municipal governance on revenue recognition within Swedish municipal waste management

ABSTRACT This paper explores the influence of municipal governance forms and structures on accounting compliance in municipal organisations. If municipal governance forms and structures influence accounting compliance, then understanding these relationships becomes important when discussing heterogeneous practice and efficient accounting regulation. The context and object of analysis is the practices of revenue recognition within the Swedish municipal solid waste management sector. Overall, this analysis identifies that financial accounting compliance is influenced by municipal governance forms and structures, and the results further highlight how financial accounting practices might diffuse through local intra-organisational processes. The results emphasise that municipal governance forms and structures are important factors when considering heterogeneous accounting practices in the municipal sector which complement the more conventional analysis of how external institutional, political and economic forces influence accounting choice and compliance.
Relationship Lending and Firms’ Leverage: Empirical Evidence in Europe

Using a novel measure of relationship lending based on the kind of information banks use to assess borrowers, we investigate the role of relationship lending in firmsâ€™ capital structure. Using a unique dataset of European manufacturing firms, we measure relationship lending based on three dimensions (closeness, soft information, exclusivity) and relate them to firmsâ€™ leverage. Overall our results support the hypothesis that supply factors matter. We find that the actual use of soft information increases leverage and only firms without soft informationâ€ intensive relationships increase their leverage through multiple relationships. However, the effect of relationship lending on leverage varies across countries.
Characteristics of Intracardiac Electrograms *

Cardiac electrograms were measured on endocardial leads on patients undergoing pacemaker implantation. The data show that small area electrodes reduce R wave amplitude, decrease width of the complex, and increase slopes. The bandwidth of the electrogram increases as the electrode area decreases. The loading of the sensing amplifier changes these characteristics. Distortion is most pronounced for small area electrodes and low lead resistances.