Miracle-dz/UniFAR-FTUs huggingface dataset:
Does NVIX matter for Volatility ? — — Evidence from Asia-Pacific Markets

Using news-based implied volatility (NVIX) that measures uncertainty, we examine the impact of NVIX on the stock market volatility in both long and short-term among Asia-Pacific markets. We find that NVIX do not well explain long-term volatility variants in the full sample period using GARCH-MIDAS model, and it is positively associated with market volatility after Financial Crisis. We also conclude that impact of NVIX is more efficient in determining short-term volatility than long-term volatility, indicating that the impact of NVIX is short-lived and information that investors concern could be quickly reflected in the stock market volatilities.
Diagnosis and Management of Ectopic Pregnancy in King Abdulaziz University Hospital: A Four Year Experience

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Yield Components and Yield of Haricot Bean ( Phaseolus vulgaris L . ) Under Different Irrigation Frequency and Planting Density Treatments

An experiment was undertaken to determine the yield component and yield of haricot bean (Phaseolus vulgaris L.) varieties in the semiarid region of Dire Dawa, Ethiopia. The experiment was a split plot with three irrigation frequencies as main plots and a combination of three planting densities and two haricot bean varieties as subplots, all of which replicated three times. Irrigation frequencies consisted of 1, 0.67, and 0.5 irrigation water to cumulative pan evaporation (IW/CPE ratio) thereby fixing the depth of IW to 60 mm, planting densities of 15.6, 25, and 35.7 (plants m ) and two haricot bean varieties, ‘Roba-1’ and ‘Mexican-142’ were considered. Different planting densities were employed by changing planting distances within cultivation rows. Plant data on dry biomass/plant, number of branches bearing pods, number of pods/primary branch, number of pods/plant, pod length and width, number of beans/pod, number of beans/plant, 100-bean weight and harvest index at harvest were recorded. Increasing irrigation frequency from 0.5 IW/CPE to 0.67 IW/CPE and to 1 IW/CPE significantly increased all parameters. On the contrary, increasing population densities caused a significant reduction in the parameters. Averaged over planting density and variety, yield/ha and soil water depletion increased significantly with the increase in irrigation frequency. These results showed that irrigation given at 1 IW/CPE can give maximum yield of both haricot bean varieties in the semi-arid condition of Dire Dawa. _____________________________________________________________________________________________________________
Evolution of increased adult longevity in Drosophila melanogaster populations selected for adaptation to larval crowding

In holometabolous animals such as Drosophila melanogaster, larval crowding can affect a wide range of larval and adult traits. Adults emerging from high larval density cultures have smaller body size and increased mean life span compared to flies emerging from low larval density cultures. Therefore, adaptation to larval crowding could potentially affect adult longevity as a correlated response. We addressed this issue by studying a set of large, outbred populations of D. melanogaster, experimentally evolved for adaptation to larval crowding for 83 generations. We assayed longevity of adult flies from both selected (MCUs) and control populations (MBs) after growing them at different larval densities. We found that MCUs have evolved increased mean longevity compared to MBs at all larval densities. The interaction between selection regime and larval density was not significant, indicating that the density dependence of mean longevity had not evolved in the MCU populations. The increase in longevity in MCUs can be partially attributed to their lower rates of ageing. It is also noteworthy that reaction norm of dry body weight, a trait probably under direct selection in our populations, has indeed evolved in MCU populations. To the best of our knowledge, this is the first report of the evolution of adult longevity as a correlated response of adaptation to larval crowding.
Serum Bepridil Concentration for Safety Rhythm Control Strategy in Patients with Atrial Tachyarrhythmias

Seiji Miura, MD, Masataka Sumiyoshi, MD, Hiroto Tsuchiya, MD, Masaki Maruyama, MD, Seigen I, MD, Iwao Okai, MD, Yoshiyuki Masaki, MD, Shinya Okazaki, MD, Kenji Inoue, MD, Yasumasa Fujiwara, MD, Kaoru Komatsu*, MD, Hidemori Hayashi*, MD, Gaku Sekita*, MD, Takashi Tokano**, MD, Yuji Nakazato***, MD, and Hiroyuki Daida*, MD Department of Cardiology, Juntendo University Nerima Hospital, Tokyo, Japan * Department of Cardiology, Juntendo University School of Medicine, Tokyo, Japan **Department of Cardiology, Juntendo University Shizuoka Hospital, Izunokuni-shi, Japan ***Department of Cardiology, Juntendo University Urayasu Hospital, Urayasu, Japan
Relevance of EHEC O 104 : H 4 in fenugreek seeds which are processed into other foods than sprouts and germ buds

There is a high probability that the cause for the EHEC outbreak event in Germany and France in May and June 2011 was attributable to contaminated fenugreek seeds and sprouts grown from them (see BfR Opinion "Relevance of sprouts and germ buds as well as seeds for sprout production in the current EHEC O104:H4 outbreak event in May and June 2011 " http://www.bfr.bund.de/cm/349/relevance_of_sprouts_and_germ_buds_as_well_as_seeds_f or_sprouts_production_in_the_current_ehec_o104_h4_outbreak_event_in_may_and_june_2 011.pdf). According to the current state of knowledge, sprouts from fenugreek seeds were involved in the outbreak event. However, the seeds are not only used for sprout production. Therefore, the Federal Institute for Risk Assessment (BfR) has assessed the relevance of EHEC O104:H4 in fenugreek seeds which are used in different food including food supplements. Whether these products can cause an infection if processed with contaminated fenugreek seeds is primarily determined by the preparation and processing methods. Depending on the producer and product, these methods can be very different and are, thus, not known in detail to BfR.
The effect of damping in prosthetic ankle and knee joints on the biomechanical outcomes: A literature review

Background: Given the growing number of variable-damping prosthetic knee and ankle components and broad number of potential biomechanical outcomes, a systematic review is needed to assess advantages of damped knee and ankle units over non-damped prostheses. Objectives: This study provides an overview of the biomechanical outcomes associated with the use of prosthetic knees and ankles with damping mechanisms in individuals with lower limb amputation. Study design: Literature review. Methods: A systematic search was performed through PubMed, Science Direct, Web of Science, Cochrane, and Scopus databases from June 1994 to March 2016. The level of evidence of each article was assessed using a 13-element checklist for evaluating non-randomized controlled trials for quality assessment. Afterward, the studies were classified as A-level, B-level, or C-level based on total score and positive scores from certain key categories. Results: In total, 22 papers remained for the quality assessment based on the inclusion criteria. In total, 15 studies scored sufficiently high quality scores to be classified. One article scored as A-level, eight as B-level, and six as C-level. In total, 10 studied knees and 5 examined ankles. Sample sizes ranged from 5 to 28 subjects. Conclusion: Available studies were evaluated in detail and biomechanical outcomes were extracted from the studies that met criteria. Results of this review indicate that study methodology and outcome measures were heterogeneous across reviewed papers. This could be an explanation for inconsistent findings of the reviewed studies. Only self-selected gait speed showed a consistent difference when dampers were applied to the leg. Thus, further research is required in this area. Clinical relevance This study provides an overview of evidence related to prosthetic knee and foot/ankle components with damping attachments. Research related to biomechanical outcomes is of great importance for researchers and practitioners in this area. The studies drew mixed conclusions, but walking speed was consistently different for damped versus non-damped components.
Improved Sentiment Detection via Label Transfer from Monolingual to Synthetic Code-Switched Text

Multilingual writers and speakers often alternate between two languages in a single discourse. This practice is called “code-switching”. Existing sentiment detection methods are usually trained on sentiment-labeled monolingual text. Manually labeled code-switched text, especially involving minority languages, is extremely rare. Consequently, the best monolingual methods perform relatively poorly on code-switched text. We present an effective technique for synthesizing labeled code-switched text from labeled monolingual text, which is relatively readily available. The idea is to replace carefully selected subtrees of constituency parses of sentences in the resource-rich language with suitable token spans selected from automatic translations to the resource-poor language. By augmenting the scarce labeled code-switched text with plentiful synthetic labeled code-switched text, we achieve significant improvements in sentiment labeling accuracy (1.5%, 5.11% 7.20%) for three different language pairs (English-Hindi, English-Spanish and English-Bengali). The improvement is even significant in hatespeech detection whereby we achieve a 4% improvement using only synthetic code-switched data (6% with data augmentation).
Then the mixed finite elementdiscretization of ( 2 ) is definedas :

We present a multigrid solver for the exponential fitting method, applied to the current continuity equations of semiconductor device simulation in two dimensions. The exponential fitting method is based on a mixed finite element discretization using the lowest-order Raviart-Thomas triangular element. This discretization method yields a good approximation of front layers and guarantees current conservation. The corresponding stiffness matrix is an M-matrix. "Standard" multigrid solvers, however, cannot be applied to the resulting system, as this is dominated by an unsymmetric part, which is due to the presence of strong convection in part of the domain. To overcome this difficulty, we explore the connection between Raviart-Thomas mixed methods and the nonconforming Crouzeix-Raviart finite element discretization. In this way we can construct nonstandard prolongation and restriction operators using easily computable weighted L 2projections based on suitable quadrature rules and the upwind effects of the discretization. The resulting multigrid algorithm shows very good results, even for real-world problems and for locally refined grids.
NUTRIENT , MINERAL , ANTIOXIDANT , AND ANTHOCYANIN PROFILES OF DIFFERENT CULTIVARS OF SYZYGIUM CUMINI ( JAMUN ) AT DIFFERENT STAGES OF FRUIT MATURATION

The study reports profiles of nutrients, minerals, bioactive phytochemicals, and anthocyanins in four cultivars of Syzygium cumini (jamun) fruit at four maturation stages designated as D1 (light-green: very early stage of fruit-set), D2 (dark-green: full-size unripe stage), D3 (pink: semi-ripe stage), and D4 (deep-purple: fully ripe stage). No previous study has investigated profiles of these constituents in jamun at different fruit maturation stages. The most significant findings of this study relate with anthocyanins, not reported heretofore, the biosynthesis of which started as the aglycones of delphinidin and cyanidin at as early as D1 stage when sugars as their glycone components were not yet detected, and the first-time report of pelargonidin in jamun. Further, a total of five anthocyanins were identified, namely, cyanidin 3,5-diglucoside, delphinidin 3glucoside, cyanidin 3-glucoside, malvidin 3-glucoside, and pelargonidin 3-glucoside. Yet another new information noted during the identification of anthocyanins was that all previous studies on jamun fruit had reported diglucosides as the major anthocyanins, whereas except for cyanidin diglucoside in the present study all other anthocyanins (also including cyanidin) were identified as monoglucosides. All cultivars showed high +90% DPPH scavenging ability, which may be attributed to the collective participation of several antioxidant components such as ascorbic acid, total phenols, and total anthocyanins, all present in high contents in the jamun fruit.
Non-medical use of prescription drugs and HIV risk behaviour in transgender women in the Mid-Atlantic region of the United States

Male-to-female transgender women (TGW) experience high rates of substance use and HIV. A recent substance use trend is the use of prescription medication without a doctor’s consent. No research to date has examined the associations between this non-medical use of prescription drugs and HIV risk behaviour in TGW. In the present study, TGW recruited from community venues (N = 104) in the Mid-Atlantic region of the United States completed surveys assessing demographic information, non-medical use of prescription drugs, other substance use, injection practices and sexual risk behaviour. Twenty-four per cent of the sample reported lifetime non-medical use of prescription drugs across the following categories: analgesics (21.2%), anxiolytics (14.4%), stimulants (12.5%) and sedatives (8.7%). Participants reporting non-medical use of prescription drugs were more likely to report other substance use, needle use to inject drugs, injecting silicone and sharing needles. In multivariable analyses, non-medical use of prescription drugs was associated with unprotected sex, sex after engaging in substance use, and commercial sex work, after controlling for demographic factors. Self-esteem and social support from family served as protective factors for non-medical use of prescription drugs. HIV-prevention programmes focused on TGW in the United States may wish to expand their assessment of substance use to include the use of prescription medications without a physician’s consent.
Frequency of the VNTR-Polymorphisms at the PAH Gene in the Iranian Azeri Turkish Patients with Phenylketonuria.

INTRODUCTION This study was carried out to determine the frequency of the VNTR-polymorphisms at the PAH gene in the Iranian Azeri Turkish patients with phenylketonuria (PKU) and normal controls. MATERIAL AND METHODS The VNTR-polymorphisms were determined by PCR in 43 PKU patients as well as 43 controls. OUTCOMES The frequencies of VNTR-alleles were 13(15.1%), 3(3.49%), 64(74.4%), 5(5.81%), and 1(1.16%) in the patients and 43(50%), 0(0%), 42(48.8%), 0(0%), and 1(1.16%) in the controls regarding 3, 7, 8, 9, and 11 repeat copies, respectively. The VNTR alleles with 12 and 13 repeats were not found in our samples. The frequencies of VNTR-genotypes were 25(58.1%), 1(2.33%), 1(2.33%), 10(23.3%), 2(4.65%), 2(4.65%), 1(2.33%), 1(2.33%), and 0(0%) in the patients and 13(30.2%), 13(30.2%), 0(0%), 16(37.2%), 0(0%), 0(0%), 0(0%), 0(0%) and 1(2.33%) in the controls regarding VNTR8/VNTR8, VNTR3/VNTR3, VNTR3/VNTR9, VNTR8/VNTR3, VNTR8/VNTR9, VNTR7/VNTR9, VNTR7/ VNTR8, VNTR8/VNTR11, and VNTR3/VNTR11 genotypes, respectively. The comparisons of VNTRpolymorphisms imply that there are statistically significant differences between the patients and controls regarding VNTR3, VNTR8, and VNTR9 alleles as well as VNTR8/VNTR8 and VNTR3/VNTR3 genotypes (all P-Value <0.05). The frequency of "risk-associated genotype of VNTR8/VNTR8" was significantly higher in the cases. CONCLUSION It is concluded that this position is heterozygous and there were statistically significant differences between patients and controls concerning the VNTR8/VNTR8 genotype. We found higher frequencies of disease-associated genotype in our samples than controls. This report is the first in its own type in the west Azerbaijani population. Further studies require assessing how this genotype predicts adverse outcomes in tested population.
Short fiber reinforced composite in restoring severely damaged incisors

Abstract Objective. To evaluate the static-load-bearing capacity of severely damaged endodontically-treated incisors restored with short fiber composite (SFC) as a direct post-core-crown complex and to investigate the effect of SFC on the failure mode of the restorations. Materials and methods. The clinical crowns of 40 maxillary incisors were prepared by cutting 2/3 parts of the crown horizontally. Five groups were fabricated (n = 8) using the direct technique; Group A: Crown restorations from conventional composite (CC); Group B: FRC-posts with core-crown restorations from CC; Group C: Crown restorations from SFC; Group D: FRC-posts and core-crown restorations from SFC; Group E: Post–core-crown restorations from SFC. The posts were cemented with dual-cure resin cement. The restorations were polymerized with a hand-light curing unit. All restored teeth were stored in distilled water at 37°C for 5 days before they were statically loaded. Initial fracture (IF) and final fracture (FF) were recorded. Failure modes were visually examined. Results. ANOVA revealed that SFC restorations had greater IF (469.8 N) and FF load values (515.8 N) (p < 0.05) than the CC restorations (164.8 N). No significant difference for both IF and FF was observed among groups C, D and E. Group E revealed a more favorable fracture mode than any other material combination used. Conclusion. The use of SFC as a restorative material for fabricating the direct composite post-core-crown restorations of severely damaged incisors provided improved load-bearing capacity than CC used alone or with FRC post reinforcement.
The effect of C 1 inhibitor on myocardial ischemia and reperfusion injury

Background—Activation of the complement system has been demonstrated to be an important mechanism in the mediation of myocardial ischemia and reperfusion (MIR) injury. C1 inhibitor (C1INH) has been shown to be beneficial in experimental MIR models. The underlying mechanism of this effect has been assumed to result primarily from inhibition of complement system activation. We recently demonstrated that C1INH plays a direct role in suppression of leukocyte transmigration in the mouse intestinal ischemia and reperfusion model. The purpose of this study was to investigate the mechanism of the beneficial effect of C1INH in mouse MIR model. Methods—C57BL/6, C1INH-deficient (C1INH-/-) and C3-deficient mice (C3-/-) were subjected to 30 min (C57BL/6 and C1INH-/-) or 60 min (C3-/-) occlusion of the left anterior descending branch (LAD) of the coronary artery followed by 4h reperfusion. C1INH or reactive center cleaved inactive C1INH (iC1INH) was injected intravenously 5min before reperfusion. Results—Myocardial infarct size relative to the area at risk or relative to left ventricular area was significantly reduced in C1INH treated WT, C1INH-/and C3-/mice compared with vehicletreated mice. MIR induced an increase in myocardial polymorphonuclear neutrophil accumulation and plasma cardiac specific troponin I levels in vehicle-treated MIR mice while C1INH treatment significantly attenuated these effects. iC1INH had a similar protective effect. Conclusions—These results suggested that C1INH prevented MIR injury in mice and that this cardioprotective effect may not solely result from complement inhibition, but might be also contributed by inhibiting leukocyte recruitment into ischemic tissue, an effect that is not mediated via protease inhibition.
Virulence-associated plasmids in Rhodococcus equi

Twenty-three strains of Rhodococcus equi from independent clinical cases were analyzed for the presence of virulence plasmid DNA. Of the clinical isolates, 19 contained an 85-kb plasmid and the remaining 4 contained a 90-kb plasmid. All of the isolates expressed 15- to 17-kDa antigens and were virulent in mice. Restriction enzyme and Southern blot analyses showed large regions of DNA homology between the 85- and 90-kb virulence plasmids. It was concluded tentatively that there are at least two virulence plasmids in R. equi and that they have a common origin.
A Novel Unsymmetrical Multi-Segment Concentric Winding Scheme for Electromagnetic Force and Leakage Flux Mitigation in HTS Power Transformers

The high axial and radial forces caused by short circuits can be very detrimental to high-temperature superconductor (HTS) windings of HTS transformers. Axial forces above the HTS winding critical value cause irreversible effects on the critical current reduction of an HTS tape. Such forces can disrupt the normal performance of HTS transformers and lead to quench phenomenon and insulation breakdown. Accordingly, any optimization in the design of HTS transformers that decreases the leakage flux and electromagnetic forces is very significant. This paper presents a novel method for reduction of leakage flux and thereby electromagnetic force in the windings of an HTS power transformer. First, concentric primary and secondary windings are subdivided into certain number of segments. In the next step, the proposed method, which is based on selecting the optimum distributive ratios for the created subwindings, is applied to the windings. In order to verify the effectiveness of the proposed method, an advanced finite-element method has been used. The method uses accurate and nonlinear E-J power law for defining the superconductivity characteristic. The results showed the efficiency of the applied method to mitigate the radial and axial leakage flux and thereby electromagnetic forces in the windings of the HTS transformer.
Adrenomedullin as a Novel Promising Therapeutic Approach

Since 1993, the year on which adrenomedullin was discovered, a none- stop researches were established to identify this promising peptide: its source, fate, pathway, mechanism of action inside the body, how can we involve this peptide into therapeutic field of medicine. This review handled several original papers that covered several brunches of medicine; all of them shared the therapeutic approach of adrenomedullin besides sharing the puzzle of being short in duration of action and its final fate.
The role of hydrogen sul fi de in homocysteine-induced cardiodynamic effects and oxidative stress markers in the isolated rat heart

This study aimed to assess the role of H2S in homocysteine-induced cardiodynamic effects in the isolated rat heart. The hearts were retrogradely perfused according to the Langendorff technique. The maximum and minimum rates of pressure in the left ventricle (dp/dt max, dp/dt min), systolic and diastolic left ventricular pressures (SLVP, DLVP), heart rate (HR), and coronary flow (CF) were measured. A spectrophotometrical method was used to measure the following oxidative stress markers: index of lipid peroxidation (thiobarbituric acid reactive substances, TBARS), nitrite level (NO2 ), superoxide anion radicals (O2 ), and hydrogen peroxide (H2O2) concentrations. The administration of 10 μmol/l DL-homocysteine (DL-Hcy) alone decreased dp/dt max, SLVP, and CF but did not change any oxidative stress parameters. The administration of 10 μmol/l DL-propargylglycine (DL-PAG) decreased all cardiodynamic parameters and increased the concentration of O2 . The co-administration of DL-Hcy and DL-PAG induced a significant decrease in all estimated cardiodynamic parameters and decreased the concentration of NO2 − and O2 − but increased the levels of TBARS and H2O2. Homocysteine shows a lower pro-oxidative effect in the presence of hydrogen sulfide (H2S), which indicates a potential anti-oxidative capacity of H2S.