Miracle-dz/UniFAR-FTUs huggingface dataset:
Air–Ground Channel Characterization for Unmanned Aircraft Systems—Part III: The Suburban and Near-Urban Environments

Applications for unmanned aircraft systems (UAS), or “drones,” are increasing rapidly. In order to provide safe and reliable links to integrate UAS into the National Airspace System (NAS), control and nonpayload communication (CNPC) system requirements are being specified. A comprehensive knowledge of the air-to-ground (AG) channels in the bands of interest (C-band and L-band) plays an essential role. The NASA Glenn Research Center has sponsored an AG channel measurement campaign for most of the typical ground site (GS) local environments, including over water [8], hilly/mountainous [9], suburban, and near-urban. As a continuation of our prior study, this paper addresses the suburban and near-urban scenarios. Our developed AG channel models include path loss, small-scale fading Ricean K factors, spatial and interfrequency correlations for multiple aircraft antennas, root-mean-square (RMS) delay spread, and wideband tapped delay line (TDL) models. The path loss is described by either log-distance or two-ray models, with small corrections for flight direction. The K factors were 12 (14) dB in L-band and 27.4 (28.5) dB in C-band in near-urban (suburban) environments. The interband signals were uncorrelated, but the intra-band signals were highly correlated, with the median correlation coefficient greater than 0.85. The C-band RMS delay spread was on average 10 to 60 ns, with maximum of approximately 4 μs. The TDL models are composed of the line-of-sight (LOS) component, a ground reflection, and up to seven intermittent multipath components (MPCs). Relative power, phase, occurrence probability, duration, and excess delays for these intermittent MPCs are quantified. An algorithm to simulate the AG channel impulse response (CIR) via the TDL models is provided.
A Comparison of Frailty Indexes for the Prediction of Falls, Disability, Fractures, and Mortality in Older Men

OBJECTIVES: To compare the validity of a parsimonious frailty index (components: weight loss, inability to rise from a chair, and poor energy (Study of Osteoporotic Fractures (SOF) index)) with that of the more complex Cardiovascular Health Study (CHS) index (components: unintentional weight loss, low grip strength, poor energy, slowness, and low physical activity) for prediction of adverse outcomes in older men.
Comparison of airway resistance measurements by the forced oscillation technique and the interrupter technique for detecting chronic obstructive pulmonary disease in elderly patients.

Pulmonary function tests provide an objective means to verify ventilatory dysfunction and to estimate its severity in respiratory disorders. Measurement of forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC) is considered to be the basic tests for the assessment of airway obstruction. Although they are useful diagnostically and prognostically, the results of FEV1 and FVC are strongly dependent on the cooperation of the patient. Lack of collaboration is particularly present in elderly patients because of mood alterations, fatigability or cognitive impairment.1 The forced oscillation technique (FOT) and the interrupter resistance technique are the two methods of measuring respiratory resistance during tidal breathing, they are of special interest because both of them are noninvasive, requires minimal cooperation, takes little time and can be easily repeated, especially in children and elderly subjects who cannot accomplish forced expiratory maneuvers in a reproducible manner.2
Effect of Legume Extracts on Germination, Seedling Health of Beans (Phaseolus vulgaris L.) and Soil Microorganisms

Application of undecomposed green manure has been reported to cause poor emergence and establishment of common beans in the field. Therefore, to understand the mechanisms’ contributing to the poor crop establishment, the effect of extracts from fresh and decomposed legume green manures on bean seed germination, fungal mycelial growth, spore germination and germ tube elongation were evaluated. The extracts were prepared in either ethanol or distilled water. Data was collected on percentage seed germination, seedling length, mycelial radial growth, spore germination and germ tube elongation. Ethanol extracts from fresh lablab inhibited bean germination by 56%, increased mean germination time to 8 days, and decreased germination index while ethanol extracts of groundnut and beans caused highest inhibition in bean shoot length and reduced biomass. Ethanol extracts from fresh green manures significantly inhibited fungal mycelial growth while the aqueous extracts from beans, groundnuts and soybean had significant level of antifungal activity while aqueous lablab extracts stimulated mycelial. Aqueous extract of lablab and soybean enhanced spore germination by over 70% with more pronounced effect on germ tube length and number of germ tubes by 8.0% and 13% respectively. The study comparatively reveals that the extract of lablab was inhibitory to common bean germination compared to other legume extracts and also stimulated the growth of root rot pathogens that may have resulted in poor establishment of beans.
Gene transfer with HSP 70 in rat chondrocytes confers cytoprotection in vitro and during experimental osteoarthritis

Osteoarthritis is characterized by a gradual degradation of extracellular matrix, resulting from an excess of chondrocyte cell death, mainly due to an increase in apoptotis. Recent studies have revealed the essential role of HSP70 in protecting cells from stressful stimuli. Therefore, overexpressing HSP70 in chondrocytes could represent a good strategy to prevent extracellular matrix destruction. To this end, we have developed a vector carrying HSP70/GFP, and transduced chondrocytes were thus more resistant to cell death induced by mono‐iodoacetate (MIA). To overcome the barrier‐effect of matrix, we investigated the efficacy of plasmid delivery by electroporation (EP) in rat patellar cartilage. Two days after EP, 50% of patellar chondrocytes were HSP/GFP+. After 3 months, long‐term expression of transgene was only depicted in the deep layer (20–30% positive cells). HSP70 overexpression inhibited the natural endochondral ossification in the deep layer, thus leading to a lesser decrease in chondrocyte distribution. Moreover, overexpression of HSP70, after a preventive EP transfer in rat patella, was sufficient to decrease the severity of osteoarthritis‐induced lesions, as demonstrated histologically and biochemically. In conclusion, intracellular overexpression of HSP70, through EP delivery, could protect chondrocytes from cellular injuries and thus might be a novel chondroprotective modality in rat OA. —Grossin, L. , Cournil‐Henrionnet, C. , Pinzano, A. , Gaborit, N. , Dumas, D. , Etienne, S. , Stoltz, J. F. , Terlain, B. , Netter, P., Mir, L. M. , Gillet, P. Gene transfer with HSP 70 in rat chondrocytes confers cytoprotection in vitro and during experimental osteoarthritis. FASEB J. 20, 65–75 (2006)
Monte Carlo simulations of pure liquid substituted benzenes with OPLS potential functions

Intermolecular potential functions have been developed for use in computer simulations of substituted benzenes. Previously reported optimized potentials for liquid simulations (OPLS) for benzene and organic functional groups were merged and tested in Monte Carlo statistical mechanics simulations for the pure liquids of toluene, m‐cresol, anisole, aniline, and benzonitrile at 25°C at 1 atm. The merged potential functions yielded acceptable thermodynamic results for the liquids except in the case of aniline, for which the error in the heat of vaporization was 12%. This was remedied by enhancing the polarity of the model to be more consistent with the observed dipole moment of aniline. Overall, the average errors in computed heats of vaporization and densities were then 2 and 1%, respectively. The structures of the liquids were characterized through energy and radial distribution functions. For m‐cresol and aniline, the molecules participate in averages of 1.6 and 1.4 hydrogen bonds, respectively. Condensed phase effects on the torsional energies for anisole, m‐cresol, and aniline were found to be small; m‐cresol has a slightly enhanced tendency to be nonplanar in the liquid than in the gas phase, while anisole shows the opposite pattern. © 1993 John Wiley & Sons, Inc.
Holistic Review and Conceptual Framework for the Drivers of Offsite Construction: A Total Interpretive Structural Modelling Approach

The significant ill-performances, challenges, and increasing competition within the construction sector are generating tremendous changes. One such revolution is the transition towards offsite construction (OSC). Although a plethora of studies has expounded the virtues and benefits of the approach, a holistic review and conceptual framework of the drivers of OSC is not well-established. This research draws on a multistage methodological framework of a systematic literature review, plenary discussions, and the total interpretive structural modelling (TISM) approach to build a holistic conceptual framework for the drivers of OSC. A review of 32 empirical studies distributed across four continents resulted in the extraction of 86 drivers. The 86 drivers were grouped into time, cost, quality, productivity, innovative competitiveness, market, sustainability, and policy clusters of drivers drawing on previous classifications in empirical studies. The TISM modeling revealed three hierarchical levels of the drivers, comprising dependent, linkage, and independent drivers. Based on an MICMAC analysis, “innovative competitiveness” and “sustainability” have the highest driving powers and lowest dependences, suggesting their prime significance in the adoption of OSC. Thus, this research provides a broader perspective of the drivers and may help OSC practitioners and policymakers to gain a better understanding of the ecosystem of the drivers.
Simultaneously detect and segment pedestrian

We present a framework to simultaneously detect and segment pedestrian in images. Our work is based on part-based method. We first segment the image into superpixels, then assemble superpixels into body part candidates by comparing the assembled shape with pre-built template library. A “structure-based” shape matching algorithm is developed to measure the shape similarity. All the body part candidates are input into our modified AND/OR graph to generate the most reasonable combination. The graph describes the possible variation of body configuration and model the constrain relationship between body parts. We perform comparison experiments on the public database and the results show the effectiveness of our framework.
High-Accurate Numerical Computation of Internal Impedance of Cylindrical Conductors for Complex Arguments of Arbitrary Magnitude

In this paper, a numerical model is proposed for computing the per-unit-length internal impedance of tubular cylindrical conductors for complex arguments of arbitrary magnitudes. The proposed model either numerically solves the exact formula for internal impedance consisting of modified Bessel functions or utilizes asymptotic approximations of modified Bessel functions when applicable. It is shown that the results obtained by the proposed model are highly accurate and numerically stable. The proposed model is also applicable for solid cylindrical conductors.
Serum IL‐6 Level and the Development of Disability in Older Persons

BACKGROUND: The serum concentration of interleukin 6 (IL‐6), a cytokine that plays a central role in inflammation, increases with age. Because inflammation is a component of many age‐associated chronic diseases, which often cause disability, high circulating levels of IL‐6 may contribute to functional decline in old age. We tested the hypothesis that high levels of IL‐6 predict future disability in older persons who are not disabled.
A Comparison of Methods for Determining the Rate of Force Development During Isometric Midthigh Clean Pulls

Abstract Haff, GG, Ruben, RP, Lider, J, Twine, C, and Cormie, P. A comparison of methods for determining the rate of force development during isometric midthigh clean pulls. J Strength Cond Res 29(2): 386–395, 2015—Twelve female division I collegiate volleyball players were recruited to examine the reliability of several methods for calculating the rate of force development (RFD) during the isometric midthigh clean pull. All subjects were familiarized with the isometric midthigh clean pull and participated in regular strength training. Two isometric midthigh clean pulls were performed with 2 minutes rest between each trail. All measures were performed in a custom isometric testing device that included a step-wise adjustable bar and a force plate for measuring ground reaction forces. The RFD during predetermined time zone bands (0–30, 0–50, 0–90, 0–100, 0–150, 0–200, and 0–250 milliseconds) was then calculated by dividing the force at the end of the band by the band's time interval. The peak RFD was then calculated with the use of 2, 5, 10, 20, 30, and 50 milliseconds sampling windows. The average RFD (avgRFD) was calculated by dividing the peak force (PF) by the time to achieve PF. All data were analyzed with the use of intraclass correlation alpha (ICC&agr;) and the coefficient of variation (CV) and 90% confidence intervals. All predetermined RFD time bands were deemed reliable based on an ICC&agr; >0.95 and a CV <4%. Conversely, the avgRFD failed to meet the reliability standards set for this study. Overall, the method used to assess the RFD during an isometric midthigh clean pull impacts the reliability of the measure and predetermined RFD time bands should be used to quantify the RFD.
Multi-sharing resource allocation for device-to-device communication underlaying 5G mobile networks

Device-to-device (D2D) communication can improve system spectrum efficiency in mobile networks; however, existing D2D resource allocation techniques may not work well in 5G mobile networks with many simultaneously connected devices. To address this problem, we study the multi-sharing resource allocation problem, which allows any cellular user equipment to share its radio resource with multiple D2D devices. We formulate the multi-sharing resource allocation problem and prove its NP hardness. Besides, we develop the Greedy Throughput Maximization Plus (GTM+) algorithm. Simulation results show that GTM+ is fast and outperforms existing algorithms in throughput and the number of permitted D2D pairs.
Genomic screen for genes involved in mammalian craniofacial development

Summary: Using a subtractive hybridisation approach, we enriched for genes likely to play a role in embryonic development of the mammalian face and other structures. This was achieved by subtracting cDNA derived from adult mouse liver from that derived from 10.5 dpc mouse embryonic branchial arches 1 and 2. Random sequencing of clones from the resultant library revealed that a high percentage correspond to genes with a previously established role in embryonic development and disease, while 15% represent novel or uncharacterised genes. Whole mount in situ hybridisation analysis of novel genes revealed that approximately 50% have restricted expression during embryonic development. In addition to expression in branchial arches, these genes showed a range of expression domains commonly including neural tube and somites. Notably, all genes analysed were found to be expressed not only in the branchial arches but also in the developing limb buds, providing support for the hypothesis that development of the limbs and face is likely to involve analogous molecular processes. genesis 35:73–87, 2003. © 2003 Wiley‐Liss, Inc.
Paléolithique final et Mésolithique dans le Bassin parisien et ses marges. Habitats, sociétés et environnements. Projet collectif de recherche. Bilan des activités de 2013 à 2015

Quatre-vingt-quinze chercheurs de plusieurs institutions europeennes ont directement ou indirectement œuvre a ce rapport dressant le bilan de trois annees de travaux collectifs (2013-2015) sur les societes qui peuplaient le Bassin parisien pendant le Tardiglaciaire et le debut du Postglaciaire (XIVe-VIe millenaire avant J.-C.). Apres un echantillon significatif de publications, de resumes de communications ou de theses, on y presente divers projets plus ou moins avances, notamment sur les gibiers tardiglaciaires, sur les industries lithiques du Paleolithique final ou encore sur le contexte mesolithique de realisation de bon nombre des gravures remplissant les abris sous gres du sud de l’Ile-de-France. Ensuite figurent les resumes d’une des sessions du XXVIIIe Congres prehistorique de France a Amiens : une table-ronde co-organisee par le PCR a propos des environs de 9500 avant J.-C. en Europe du Nord-Ouest. Puis l’actualite des decouvertes est presentee en annexe.
Moxifloxacin for the Treatment of Patients with Complicated Intra-abdominal Infections (the AIDA Study)

Abstract This prospective, randomized, open, international, multicenter study of adults with complicated intra-abdominal infections (cIAI) compared the efficacy and safety of sequential intravenous (i.v.) to oral (p.o.) moxifloxacin 400 mg once daily, with that of i.v. ceftriaxone 2 g once daily, plus metronidazole 500 mg three times daily, followed by p.o. amoxicillin/clavulanate 625 mg three times daily. The primary efficacy variable was clinical cure at test of cure (TOC) (day 28-42 after study entry) in the per protocol (PP) population. Of 595 patients in the study, 511 patients were valid for PP analysis (246 moxifloxacin, 265 ceftriaxone/metronidazole). Sequential moxifloxacin was noninferior to the comparator regimen - clinical cure rates at TOC were 80.9% ver-sus 82.3% (moxifloxacin versus ceftriaxone/metronidazole; 95% CI -8.9, 4.2%). The incidence of adverse events was comparable between the two treatment groups. Therefore, sequential moxifloxacin monotherapy is as effective and safe as combination therapy with i.v. ceftriaxone plus i.v. metronidazole followed by oral amoxicillin/clavulanate for the treatment of cIAI.
Assessment of Accurate Self-Knowledge

Despite ongoing theoretical interest in the accuracy of self-knowledge and its implications for mental health, few researchers have yet to tackle this topic directly. This may be due, in part, to several factors that make assessing individual differences in accurate self-knowledge especially difficult. In this article, we present a method for the assessment of accurate self-knowledge that relies on information gathered from the self, knowledgeable others, and observations of behavior in the laboratory, and we provide psychometric support for this newly developed assessment procedure. Specifically, we present evidence for internal consistency reliability, convergent and discriminant validity, and criterion-related validity. Other researchers interested in studying the accuracy of self-knowledge might wish to adopt this procedure in their own research endeavors.
The Effects of General Anesthesia on Whole Body and Regional Pharmacokinetics of Local Anesthetics at Toxic Doses

BACKGROUND:Local anesthetic toxicity is often studied experimentally in anesthetized subjects, but clinical toxicity usually occurs in conscious patients. In this study, we determined the influence of general anesthesia on the pharmacokinetics of six local anesthetics administered IV at approximately the highest recommended doses. METHODS:Chronically instrumented ewes (approximately 45–50 kg, n = 18) were infused over 3 min with (base doses as HCl salts) bupivacaine (100 mg), levobupivacaine (125 mg), ropivacaine (150 mg), lidocaine (350 mg), mepivacaine (350 mg), or prilocaine (350 mg), on separate occasions when conscious and halothane anesthetized. Serial arterial, heart, and brain venous blood drug concentrations were measured by achiral/chiral high-performance liquid chromatography, as relevant. Whole body pharmacokinetics were assessed by noncompartmental analysis; heart and brain pharmacokinetics were assessed by mass balance. Drug blood binding, in the absence and presence of halothane, was assessed by equilibrium dialysis in vitro. RESULTS:Blood local anesthetic concentrations were doubled with anesthesia because of decreased whole body distribution and clearance (respectively, to 33% and 52% of values when conscious). Heart and brain net drug uptake were greater under anesthesia, reflecting slower efflux from both regions. Clearances of R-bupivacaine > S-bupivacaine and R-prilocaine > S-prilocaine, but, mepivacaine clearance was not enantioselective. Halothane did not influence blood binding of the local anesthetics. CONCLUSIONS:General anesthesia significantly changed whole body and regional pharmacokinetics of each local anesthetic as well as the systemic effects. General anesthesia is thus an important but frequently overlooked factor in studies of local anesthetic toxicity.
Same Chemotherapy Regimen Leads to Different Myelotoxicity in Different Malignancies: A Comparison of Chemotherapy-Associated Myelotoxicity in Patients With Advanced Ovarian and Non–Small-Cell Lung Cancer

Carboplatin–paclitaxel chemotherapy combination is the standard first-line treatment of advanced ovarian cancer and is the most commonly used treatment combination shown to be effective in advanced non–small-cell lung cancer (NSCLC). The most important dose-limiting side effect is hematologic toxicity. In this study, the severity of treatment-related myelotoxicity is compared in patients with advanced ovarian and lung cancers who received same schedule of carboplatin–paclitaxel. The study was prospectively performed from February 2009 to July 2011 and involved 103 patients with stages Ic–IV ovarian (n = 51) and advanced NSCLC (n = 52) who were administered a maximum of 6 cycles of carboplatin–paclitaxel as a first-line treatment. Full blood counts were measured before treatment, before each chemotherapy cycle during therapy, and at the first and sixth month after therapy. The median ages were 59 years (range, 35–77 years) for patients with NSCLC and 56 years (range, 38–75 years) for patients with ovarian cancer. The frequencies of anemia were 17% and 28.6% before the initiation of chemotherapy, 39.2% and 68.0% at the third cycle of treatment, and 44.2% and 45.2% at the sixth cycle of treatment in patients with NSCLC and ovarian cancer, respectively. Initial leukopenia rates were 3.4% and 0%; at the third cycle 46.0% and 41.2%; and at the sixth cycle 41.9% and 48.8% in patients with NSCLC and ovarian cancer, respectively. At the third cycle, 2.5% of the patients with NSCLC and 10.4% of the patients with ovarian cancer had thrombocytopenia, and at the sixth cycle, 23.3% of the patients with NSCLC and 25% of the patients with ovarian cancer had thrombocytopenia. Hemoglobin, leukocyte, and platelet values at the third cycle were significantly lower than those at admission in both cancer groups. Declines in hemoglobin levels in patients with NSCLC and in platelets in patients with ovarian cancer at the sixth cycle were statistically significant compared with the third cycle. In conclusion, the same schedule of chemotherapy may lead to different myelotoxicities in different types of cancer. These results should be taken into consideration in terms of supportive care and management of toxicity.
TOP2A and HER2 gene amplification as predictors of response to anthracycline treatment in breast cancer

The purpose of this study was to evaluate amplification of topoisomerase IIalpha (TOP2A) and HER2 genes as predictors of response to chemotherapy in advanced breast cancer. Gene copy number of TOP2A and HER2 were analysed with chromogenic in situ hybridization (CISH) on paraffin-embedded tissue sections from the primary tumour of 85 patients treated with anthracycline containing chemotherapy. TOP2A gene amplification was present in 14 (16%) and HER2 gene amplification in 38 (45%) of the primary tumours. Two of the 14 cases with TOP2A amplification were amplified without concurrent HER2 amplification. Neither TOP2A nor HER2 gene amplification were significantly associated with response to chemotherapy (p = 0.35 and p = 0.49, respectively).