Miracle-dz/UniFAR-FTUs huggingface dataset:
The impact of Helicobacter pylori infection on coronary heart disease in a Korean population.

BACKGROUND/AIMS Although several studies have claimed that Helicobacter pylori (H. pylori) infection is related to cardiovascular disease, it is still uncertain whether it is related to the acute process or the chronic inflammatory atherosclerotic changes. The aim of our study was to confirm the impact of active H. pylori infection on coronary heart disease, acute inflammatory factors, and the coagulation factors. METHODS A total of 94 patients completed questionnaires about occupation, smoking, past medical history, and socio-economic status. The serum of the subjects was drawn for a low density lipoprotein test, white blood cell count, C reactive protein, fibrinogen, homocysteine, prothrombin time, activated partial thrombin time, plasminogen activator inhibitor type-1, and tissue-type plasminogen test. All of the subjects underwent a coronary angiography and an upper gastrointestinal endoscopy for the diagnosis of coronary heart disease and H. pylori infection, respectively. RESULTS There was no significant difference in acute inflammatory factors, coagulation factors, atheromatous burden score, and Jeopardy score between the H. pylori-infected group and non-infected group. Odds ratio of H. pylori infection on coronary heart disease was 2.59 (95% CI, 0.80-6.17), but it diminished below 1.0 (95% CI, 0.14-1.36) after adjusting for conventional risk factors such as age, gender, diabetes, hypertension, smoking, body mass index and socio-economic status. CONCLUSIONS H. pylori infection is not an independent risk factor for coronary heart disease, and it does not alter the coagulation system or evoke the systemic inflammatory response.
Multidetector row CT demonstration of inner and middle ear structures

The aim of this study is to evaluate the anatomical details of the inner ear and middle ear, using multidetector row CT. Temporal bone CT scans were obtained using 16‐detector row CT scanner (Lightspeed 16, General Electric Medical Systems, Milwaukee, WI) in 30 patients with dizziness, vertigo, or hearing loss. The three‐dimensional (3D) images were reconstructed with volume rendering techniques. The 3D images were reviewed by two radiologists and scored by using a three‐point quality rating for qualitative assessment of the 23 representative structures of the middle and inner ear. The malleus, incus, and facial nerve canal were identified in all patients. The incudomalleolar joint appeared fused in all patients. The stapes were seen clearly in 27 (90%) of 30 patients except in three patients. Among the three remaining patients, there was one who had effusions in the middle ear cavity. Another patient had left cholesteatoma. The third patient had normal middle ear cavity. The cochlea and the three semicircular canals (anterior, posterior, and lateral) were well demonstrated in 29 (97%) of 30 patients except for one old woman with osteoporosis. Sixteen‐detector row CT imaging of temporal bone with advanced 3D reformation yields state‐of‐the‐art anatomical details of the temporal region useful to address anatomical localization issues and ease conceptual structural learning. Clin. Anat. 19:337–344, 2006. © 2005 Wiley‐Liss, Inc.
Testing the Nest-Homing Abilities of a Phytotelm-breeding Frog, Chirixalus eiffingeri (Rhacophoridae)

Abstract We conducted a manipulative experiment to assess the homing of female Chirixalus eiffingeri to the nest. There were three experimental treatments and a control. For the control treatment, bamboo stumps were cut off at the base and reattached. In the first experimental treatment, when stumps were displaced 1 m, the proportion of stumps attended by females and the growth of tadpoles did not differ from the results of the control treatment, suggesting the 1-m stump displacement did not affect the nest homing of female frogs. In the second experimental treatment, when a bamboo stump was displaced 1 m and a new bamboo stump with tadpoles was put in its place, some females fed tadpoles in the displaced stump (3/12), but some fed tadpoles in the stump (3/12) at the original site. This finding suggests that the addition of a new stump confused the female frogs spatially, which resulted in females feeding the tadpoles in either stump. In the third experimental treatment, when a bamboo stump was displaced 1 m and a new stump without tadpoles was added at the original site, some female frogs fed tadpoles in the displaced stump (5/12) but some laid trophic eggs in the stump (4/12) at the original site, also indicating the female frogs were confused spatially. The overall results support the hypothesis that females rely on the spatial distribution of a nest stump, relative to other bamboo stumps, for nest homing to feed their offspring, and that stump location is an important cue to the nest homing of females.
Reciprocal changes in trefoil 1 and 2 expression in stomachs of mice with gastric unit hypertrophy and inflammation

H+/K+‐ATPase β‐subunit‐deficient mice (129/Sv background) display numerous pathologies in the stomach. Expression of the mutation in BALB/cCrSlc mice results in the development of an aberrant ‘mucus‐rich’ cell population. ‘Mucus‐rich’ cells have been described in stomachs of mice with autoimmune gastritis, a disease mediated by CD4+ T cells. Other pathological features of autoimmune gastritis are similar to those in H+/K+ β‐deficient mice and include a mononuclear cell infiltrate in the gastric mucosa, non‐functional or absent parietal cells, depletion of zymogenic cells, hypergastrinaemia, and gastric unit hypertrophy caused by immature cell hyperplasia. The present study investigates further the aberrant gastric ‘mucus‐rich’ cell lineage and analyses the mRNA expression of mucus cell products TFF1 and TFF2. ‘Mucus‐rich’ cells stained for both acidic and neutral mucins, and with a TFF2‐specific antibody. Stomachs from both models expressed decreased TFF1 mRNA and reciprocally increased TFF2 mRNA. The involvement of gastrin in regulating trefoil mRNA expression was also investigated using gastrin‐deficient mice. In contrast to previous findings, gastrin did not positively regulate TFF1 mRNA expression, but there was possible augmentation of TFF2. Additionally, a clear role for inflammation was established involving both polymorphonuclear and mononuclear cells in these models, and a link was found between mucosal hypertrophy and increased interleukin‐11 (IL‐11) expression. Copyright © 2005 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
Bowel necrosis associated with early jejunal tube feeding: A complication of postoperative enteral nutrition.

HYPOTHESIS Postoperative enteral nutrition may sometimes be responsible for severe complications such as mesenteri ischemia. DATA SOURCES Studies in the English literature were identified by a computer-assisted search of the MEDLINE database using the key words "enteral feeding OR jejunostomy" AND "complications OR mesenteric ischemia. " Cited references of each retrieved paper were checked for relevance. STUDY SELECTION All reports of mesenteric ischemia in the setting of postoperative enteral feeding were included. In cases of multiple articles from the same institution with overlapping patients, the most exhaustive article was included. DATA EXTRACTION All reports were abstracted for number of patients, presence of preoperative comorbidities, development of perioperative hypotension or mesenteric occlusion, and outcome. DATA SYNTHESIS Nine studies were retrieved in which enteral feedings were responsible for bowel ischemia; we report an additional case. The common clinical picture is that of a patient without significant risk factors for mesenteric ischemia, which during the early postoperative course develops nonspecific abdominal symptoms and then rapidly progresses to septic shock and eventually to multisystem organ failure and death. Mesenteric ischemia may present in up to 3.5% of enterally fed surgical patients; the associated mortality approaches 100%. The lack of specific symptoms requires a high index of suspicion for diagnosis; prompt abdominal exploration and bowel resection are the only chance for survival. CONCLUSIONS The benefits of enteral nutrition outweigh the likelihood of severe complications; when mesenteric ischemia develops, early diagnosis is challenging and the prognosis is poor.
In‐vivo three‐dimensional knee kinematics during daily activities in dogs

The canine knee is morphologically similar to the human knee and thus dogs have been used in experimental models to study human knee pathology. To date, there is limited data of normal canine 3D knee kinematics during daily activities. The objective of this study was to characterize 3D in‐vivo femorotibial kinematics in normal dogs during commonly performed daily activities. Using single‐plane fluoroscopy, six normal dogs were imaged performing walk, trot, sit, and stair ascent activities. CT‐generated bone models were used for kinematic measurement using a 3D‐to‐2D model registration technique. Increasing knee flexion angle was typically associated with increasing tibial internal rotation, abduction and anterior translation during all four activities. The precise relationship between flexion angle and these movements varied both within and between activities. Significant differences in axial rotation and coronal angulation were found at the same flexion angle during different phases of the walk and trot. This was also found with anterior tibial translation during the trot only. Normal canine knees accommodate motion in all planes; precise kinematics within this envelope of motion are activity dependent. This data establishes the characteristics of normal 3D femorotibial joint kinematics in dogs that can be used as a comparison for future studies. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:1603–1610, 2015.
NEW MARINE MEMBERS OF THE GENUS HEMISELMIS (CRYPTOMONADALES, CRYPTOPHYCEAE) 1

Cryptomonads are a ubiquitous and diverse assemblage of aquatic flagellates. The relatively obscure genus Hemiselmis includes some of the smallest of these cells. This genus contained only two species until 1967, when Butcher described seven new marine species mainly on the basis of observations with the light microscope. However, from these seven taxa, only H. amylifera and H. oculata were validly published. Additionally, the features Butcher used to distinguish species have since been questioned, and the taxonomy within Hemiselmis has remained clouded due to the difficulty in unambiguously applying his classification and validating many of his species. As a result, marine strains are often placed into one of three species—H. rufescens Parke, H. virescens Droop, or the invalid H. brunnescens Butcher—based on cell color alone. Here we applied microscopic and molecular tools to 13 publicly available Hemiselmis strains in an effort to clarify species boundaries. SEM failed to provide sufficient morphological variation to distinguish species of Hemiselmis, and results from LM did not correlate with clades found using both molecular phylogenetic and nucleomorph genome karyotype analysis, indicating a high degree of morphological plasticity within species. On the basis of molecular characters and collection geography we recognize four new marine species of Hemiselmis—H. cryptochromatica sp. nov., H. andersenii sp. nov., H. pacifica sp. nov., and H. tepida sp. nov.—from the waters around North America.
Surplus Value Production and Realization in Marxian Theory – Applications to the U.S., 1990–2015

ABSTRACT Marx's Capital shows that surplus value can be produced in one industry, yet realized as profit (and possibly revenue) by other industries over the course of circulation. This paper highlights the separation between surplus value production and realization in Marx's work, and develops a new method for estimating surplus value production at the industry level to trace out transfers of surplus value across industries. The framework is based on the ‘New Interpretation’ and links money value added to surplus value production at the industry level. Data on value added by industry for the U.S. are used to estimate surplus value production by industry. The analysis allows comparison of surplus value production and realization in each industry. The pattern of differentials between surplus value creation and realization across industries sheds light on the processes of capitalist competition and points to a source of instability for capitalist economies.
A Critical Assessment of the OECD Collaborative Study to Validate the Uterotrophic Assay for the Detection of Oestrogenic and Anti-oestrogenic Chemicals

The design and execution of a recently completed validation study on the rat uterotrophic assay for detecting oestrogens and anti-oestrogens, managed by the OECD, are critically assessed with respect to internationally agreed criteria for the validation of new in vitro and in vivo toxicity test methods. It is concluded that, while the design of the study did not take account of several important criteria for validation, the uterotrophic assay appears to reliably detect the strong and weak oestrogenic substances used in the study, which act via binding to the oestrogen receptor in vivo. However, the reliability of the assay has not been substantiated for detecting anti-oestrogens that act as antagonists, due to the involvement of an insufficient number of experiments and test chemicals. Moreover, the data do not permit an assessment of the accuracy of the prediction of oestrogenicity, and the protocols have not been sufficiently optimised with regard to controlling variables. This problem has been exacerbated by a wish to introduce as much flexibility as possible into the protocols during the formal validation phase of the study, rather than during a separate prevalidation stage. In addition, the choice between surgically treated and/or immature animals, and details of housing and husbandry conditions that are necessary for increasing the sensitivity and efficiency of the assay, need to be clarified. The assay also lacks a well-defined prediction model by which the overall relevance of the data to toxicity, and especially to human hazard, can be assessed, and no performance criteria have been established. The results of this analysis of the study indicate that it would be premature to produce an OECD test guideline for the uterotrophic assay at this time, before some of the above issues have been satisfactorily resolved.
Effect of leg dominance on change of direction ability amongst young elite soccer players

ABSTRACT Young soccer players often use one particular dominant leg (DL) to perform dynamic movements which require strength, resulting in leg asymmetry. The aim of this study was to compare, in young soccer players, the effect of using DL and non-dominant leg (NDL) on time performance of two change of direction (COD) manoeuvres in several angles of COD. Seventy-three young male soccer players (mean ± SD, age: 16.1 ± 1.8 year) participated in this study. Players performed 10-m sprints, either in a straight line or with a COD (5 m straight ahead and a turn of 45°, 90°, 135° and 180° to the opposite side of the DL or NDL). Testing for COD speed was conducted over two different manoeuvres: (1) sidestepping and (2) bypass. Maximal isometric voluntary contraction of the knee extensors/flexors and hip abductors/adductors was also measured using a handheld dynamometer. For sidestepping, COD performance with use of the DL was significantly better compared to the NDL (P < 0.05) in all angles of COD. However, bypass COD performance through use of the DL was better compared to the NDL only when turning at 135°. Additionally, strength of the knee extensors/flexors and hip abductors of the DL was significantly (P < 0.05) greater than the NDL. The use of the DL allows better COD performance than the NDL when sidestepping manoeuvre is used. However, the DL allows better COD performance than the NDL only at 135° with the use of the bypass manoeuvre. Furthermore, the greater strength of the DL compared to the NDL may contribute to COD performance difference between legs.
Retirement Savings of the Hip Generation: A Study of Retirement Preparation among Individuals in Their Fifties

Longer retirement periods coupled with the inadequacy of the Social Security system, low personal savings rates, and a decreasing trend in the prevalence of defined benefit retirement plans threaten to put a financial strain on individuals approaching retirement. To that end, we investigate retirement preparation among individuals in their fifties. Probit analysis was conducted using data from the 1995 Survey of Consumer Finances. Regarding individuals in their fifties, the findings indicate that good health and work history have significant positive effects on retirement plan eligibility. In addition, income has a significant positive effect on retirement plan eligibility for both men and women in their fifties. In contrast, age and education levels have significant negative effects regarding pension plan eligibility for both sexes in their fifties. The findings regarding retirement plan contributions indicate significant positive effects regarding income and women. Therefore, the findings generally support the hypothesis of income as a predictor of retirement plan preparation for women in their fifties. In addition, the findings indicate that women who are married or living with a partner are more likely to contribute to their pension plans through work. Education is also significant as a predictor of the decision to contribute to a pension plan for women in their fifties. In addition, the findings regarding work history (length of employment and number of weeks worked per year) and household size were significant and negative for women in their fifties. Finally, health and household status is not significant as a predictor of the decision to contribute to a pension plan. Therefore, the findings do not support the hypotheses of excellent health and homeownership as a predictor contributing to an employer sponsored pension plan.
An eHealth Application in Head and Neck Cancer Survivorship Care: Health Care Professionals' Perspectives

Background Although many cancer survivors could benefit from supportive care, they often do not utilize such services. Previous studies have shown that patient-reported outcomes (PROs) could be a solution to meet cancer survivors’ needs, for example through an eHealth application that monitors quality of life and provides personalized advice and supportive care options. In order to develop an effective application that can successfully be implemented in current health care, it is important to include health care professionals in the development process. Objective The aim of this study was to investigate health care professionals’ perspectives toward follow-up care and an eHealth application, OncoKompas, in follow-up cancer care that monitors quality of life via PROs, followed by automatically generated tailored feedback and personalized advice on supportive care. Methods Health care professionals involved in head and neck cancer care (N=11) were interviewed on current follow-up care and the anticipated value of the proposed eHealth application (Step 1). A prototype of the eHealth application, OncoKompas, was developed (Step 2). Cognitive walkthroughs were conducted among health care professionals (N=21) to investigate perceived usability (Step 3). Interviews were recorded, transcribed verbatim, and analyzed by 2 coders. Results Health care professionals indicated several barriers in current follow-up care including difficulties in detecting symptoms, patients’ perceived need for supportive care, and a lack of time to encourage survivors to obtain supportive care. Health care professionals expected the eHealth application to be of added value. The cognitive walkthroughs demonstrated that health care professionals emphasized the importance of tailoring care. They considered the navigation structure of OncoKompas to be complex. Health care professionals differed in their opinion toward the best strategy to implement the application in clinical practice but indicated that it should be incorporated in the HNC cancer care pathway to ensure all survivors would benefit. Conclusions Health care professionals experienced several barriers in directing patients to supportive care. They were positive toward the development and implementation of an eHealth application and expected it could support survivors in obtaining supportive care tailored to their needs. The cognitive walkthroughs revealed several points for optimizing the application prototype and developing an efficient implementation strategy. Including health care professionals in an early phase of a participatory design approach is valuable in developing an eHealth application and an implementation strategy meeting stakeholders’ needs.
Morphological and Molecular Characterization of Phasmarhabditis huizhouensis sp. nov. (Nematoda: Rhabditidae), a New Rhabditid Nematode from South China

The genus Phasmarhabditis is an economically important group of rhabditid nematodes, to which the well-known slug-parasite P. hermaphrodita belongs. Despite the commercial use of Phasmarhabditis species as an attractive and promising approach for pest control, the taxonomy and systematics of this group of rhabditids are poorly understood, largely because of the lack of diagnostic morphological features and DNA sequences for distinguishing species or inferring phylogenetic relationship. During a nematode sampling effort for identifying free-living relatives of Caenorhabditis elegans in Huizhou City, Guangdong, China, a novel species belonging to the genus Phasmarhabditis was isolated from rotting leaves. Detailed morphology of the gonochoristic P. huizhouensis sp. nov. was described and illustrated. The adult female has a robust body, a relatively short and wide buccal capsule conjoined by a rhabditiform pharynx. Females are characterized by a short cupola-shaped tail end bearing a slender pointed tip, with the junction flanked by a pair of ‘rod-like’ phasmids. Males have an open peloderan bursa that is supported by 9 pairs of genital papillae and 1 terminal pair of phasmids. P. huizhouensis sp. nov. is morphologically very similar to the type species Phasmarhabditis papillosa but is distinguishable by its male caudal traits. The new species is readily differentiated from other taxa in the genus by its female tail shape. Molecular phylogenetic inferences based on small subunit (SSU) and the D2-D3 domain of large subunit (LSU) ribosomal DNA genes reveal that P. huizhouensis sp. nov. forms a unique branch in both phylogenies which is genetically related to P. hermaphrodita and other parasites such as Angiostoma spp. The host associations of P. huizhouensis sp. nov. and its ability to parasitize slugs are unknown.