Miracle-dz/UniFAR-FTUs huggingface dataset:
Regional distribution of blood flow in the brain of horses at rest and during exercise.

OBJECTIVE To examine regional distribution of blood flow in the brain of horses at rest and during exercise. ANIMALS 9 clinically normal horses. PROCEDURE Regional brain blood flow was measured using radionuclide-labeled 15-microns-diameter microspheres injected into the left ventricle, while reference blood samples were obtained from the aorta. RESULTS At rest, cerebral cortex and caudate nuclei received significantly higher blood flow, compared with cerebral white matter. A similar perfusion heterogeneity existed in the cerebellum. In the brain stem, a gradual tapering of blood flow from thalamus-hypothalamus towards medulla was observed in standing horses. Progressive significant increases in heart rate and in aortic and right atrial pressures occurred during exercise at 8 and 13 m/s, and horses developed significant arterial hypoxemia and hypercapnia. Cerebral and cerebellar gray- to white-matter perfusion heterogeneity was maintained during exercise, indicating differential metabolic O2 needs. Despite arterial hypoxemia, hypercapnia, and hypertension, exercise did not result in significant changes in blood flow to the cerebral cortex and caudate nuclei whereas, in cerebral white matter, a significant decrease in blood flow was observed. In all cerebral tissues, vascular resistance increased during exercise, indicating autoregulation of cerebral blood flow. In the cerebellar cortex, blood flow increased significantly with strenuous exercise as vasodilation occurred. Vascular resistance in cerebellar white matter increased during exercise at 13 m/s. Blood flow in the medulla, pons, midbrain, and thalamus-hypothalamus was not significantly altered during exercise from that at rest. CONCLUSION Despite arterial hypoxemia, hypercapnia, and hypertension, autoregulation of cerebral and cerebellar blood flow is maintained in horses during exercise.
A structural credit risk model based on purchase order information

This study proposes a credit risk model based on purchase order (PO) information, which is called a gPO-based structural model,hand performs an empirical analysis on credit risk assessment using real PO samples. A time-series model of PO transitions is introduced and the asset value of the borrower firm is obtained using the PO time-series model. Then, we employ a structural framework in which default occurs when the asset value falls below the debt amount, in order to estimate the default probability of the borrower firm. The PO-based structural model enables us to capture borrower firms' precise business conditions on a real-time basis, which is not the case when using only financial statements. With real PO samples provided by some sample firms, we empirically show the effectiveness of our model in estimating default probabilities of the sample firms. One of the advantages of our model is its ability to obtain default probabilities reflecting borrower firms' business conditions, such as trends in PO volumes and credit quality of buyers.
Self-selected or imposed exercise? A different approach for affective comparisons

Abstract The aim of this study was to compare the psychological and physiological responses of self-selected and imposed sessions of equivalent intensities and durations and allowing to participants a free control of pace during the self-selected session. Seventeen participants completed three sessions on a cycle ergometer. Participant’s VO2Peak and lactate threshold were measured during an incremental exercise test. During the second and third sessions, participants could view a virtual cyclist on a monitor. During the self-selected session, participants were allowed free control of the intensity and duration. To ensure that the imposed session replicated the self-selected session in intensity, participants were instructed to follow an additional virtual cyclist, which was displayed on a monitor using the CompuTrainer 3D software. Power output and physiological and psychological variables were recorded during the sessions. A two-way ANOVA showed no effect of condition for power output (P = 0.940), heart rate (HR) (P = 0.965), VO2 (P = 0.898), blood lactate (P = 0.667), Feeling Scale (P = 0.877), Felt Arousal Scale (P = 0.924) and CR100 (P = 0.939). A paired t-test showed no significant difference in Physical Activity Enjoyment Scale scores between sessions (P = 0.054). In contrast to previous studies, the self-selected session did not provide better affective responses than the imposed session with same intensity and duration.
A longitudinal study of coping strategies in men receiving radiotherapy and neo-adjuvant androgen deprivation for prostate cancer: a quantitative and qualitative study.

AIM This paper reports a study on how men cope with the side-effects of radiotherapy and neo-adjuvant androgen deprivation for prostate cancer up to 1 year after treatment. BACKGROUND With early detection and improved treatments, prostate cancer survivors are living longer with the disease and the side-effects of treatment. How they cope affects their long-term physical and mental health. DESIGN A prospective, longitudinal, exploratory design using both qualitative and quantitative methods was used in this study. METHOD Between September 2006-September 2007 149 men who were about to undergo radical radiotherapy ± androgen deprivation for localized prostate cancer in Northern Ireland were recruited to the study. They completed the Brief Cope scale at four time-points. RESULTS Acceptance, positive reframing, emotional support, planning and, just getting on with it, were the most common ways of coping. Fewer men used coping strategies less at 6 months and 1 year after radiotherapy in comparison to pre-treatment and 4-6 weeks after radiotherapy. Interviews with these men demonstrated that men adapted to a new norm, with the support of their wives/partners and did not readily seek professional help. A minority of men used alcohol, behavioural disengagement and self blame as ways of coping. CONCLUSION Men used a variety of ways of coping to help them deal with radiotherapy and neo-adjuvant androgen deprivation for up to 12 months after radiotherapy. Interventions need to be developed to take account of the specific needs of partners of men with prostate cancer and single men who have prostate cancer.
Isoflavone Composition within Each Structural Part of Soybean Seeds and Sprouts

Isoflavone content in various parts of six soybean cultivars and soybean sprout during germination was analyzed by high performance liquid chromatography. The parts analyzed were seed coat, cotyledon, and axis for seeds and whole sprout, root, hypocotyl, and cotyledon for sprout. Two cultivars, Aga3 which is known to have the smallest seed size and the highest isoflavone content among the Korean soybean cultivars and Pungsannamulkong which is the most widely being used as soy-sprout, were selected for sampling from 1 to 10 days after germination. At the same weight, the order of isoflavone content increased from seed coat to cotyledon to axis. The highest total isoflavone (isoflavone × dry weight) content was observed in the cotyledon and the lowest in the seed coat. The cotyledon of the Aga3 variety had the highest total isoflavone content and the lowest was measured in the Pungsannamulkong variety. The highest total isoflavone content, 10,788μg/g, was observed in whole sprouts (cotyledon+hypocotyl+root) on day 7 for Aga3. After day 7, there was a decreasing trend in isoflavone content as the germination period increased. Total isoflavone content in the cotyledon of Aga3 significantly increased after seed germination, whereas the isoflavone content in the cotyledon of Pungsannamulkong decreased. However, total isoflavone content in the root of both varieties increased while isoflavone content in the hypocotyls decreased after seed germination.
Determinants Of Customer Loyalty: A Preliminary Study On A Prominent Bank In Malaysia

The study was conducted to identify the determinants of customer loyalty as it has become a critical aspect of maintaining organization permanence. There are three independent variables being tested in this study, which are, perceived service quality, emotional satisfaction, and corporate reputation. This study replicated the study done at a Tunisian Bank. Using convenience sampling as a sampling technique, the questionnaires had been personally distributed to 152 respondents. The results showed that two out of three hypotheses were supported. The study recommended a bigger sample size for future researcher.
Mepolizumab for severe refractory eosinophilic asthma: evidence to date and clinical potential

Severe asthma is characterized by major impairment of quality of life, poor symptom control and frequent exacerbations. Inflammatory, clinical and causative factors identify different phenotypes and endotypes of asthma. In the last few years, new treatment options have allowed for targeted treatments according to the different phenotypes of the disease. To accurately select a specific treatment for each asthmatic variant, the identification of appropriate biomarkers is required. Eosinophilic asthma is a distinct phenotype characterized by thickening of the basement membrane and corticosteroid responsiveness. This review reports the latest evidence on an anti-IL-5 monoclonal antibody, mepolizumab, a new and promising biological agent recently approved by the FDA specifically for the treatment of severe eosinophilic refractory asthma.
Correlation between Emotional Intelligence and Creativity Factors

The purpose of this research was to study the relationship between emotional intelligence and creativity in Student University. The statistical population of the research included 1370 students. The sample size was determined by cluster sampling method (n=375). In this study two standard questionnaires were used, one relating to EQ and the other to creativity. The reliability and validity of these two instruments were reported to be significant in different studies. The findings indicated that there was significant and positive relationship between Creativity its subscales with EQ.
New Insight into the Spatial Distribution of Novae in M 31

We use a Monte Carlo technique together with a simple model for the distribution of dust in M31 to investigate the observability and spatial distribution of classical novae in M31. By comparing our model positions of novae to the observed positions, we conclude that most M31 novae come from the disk population, rather than from the bulge population as has been thought. Our results indicate that the M31 bulge–to–disk nova ratio is as low as, or lower than, the M31 bulge–to–disk mass ratio. Subject headings: dust, extinction — galaxies: individual (M31) — novae, cataclysmic variables
Glenohumeral internal rotation deficit in table tennis players

ABSTRACT Table tennis requires rapid and extreme movements that may result in shoulder adaptations, such as glenohumeral internal rotation deficit, which is a risk factor for several injuries. This study compared range of motion of internal and external rotation and total rotation motion of glenohumeral joint between dominant and non-dominant shoulders of table tennis players. This is a cross-sectional observational study. Twenty healthy male table tennis players that were enrolled in an official table tennis league took part in this study (mean age: 22.9 ± 12.9 years, time of sports practice: 6.2 ± 7.12 years). Measurements of passive glenohumeral external rotation and internal rotation were taken with the individuals in the supine and sidelying positions. Total rotation motion was calculated by summing external and internal rotations. The dominant side showed decreased internal rotation when compared to non-dominant side in both supine (mean difference: 14.9°, p = 0.02) and sidelying positions (mean difference: 16.3°, p = 0.01). No significant difference (p > 0.05) was found for external rotation and total rotation motion between dominant and non-dominant shoulders. The findings indicate that table tennis players exhibit glenohumeral internal rotation deficit of dominant shoulder.
Behavioral / Cognitive Neuroanatomy Predicts Individual Risk Attitudes

Sharon Gilaie-Dotan,1* Agnieszka Tymula,2,* Nicole Cooper,3 Joseph W. Kable,3 Paul W. Glimcher,4 and Ifat Levy5 1Institute of Cognitive Neuroscience, University College London, London WC1N 3AR, United Kingdom, 2School of Economics, University of Sydney, Sydney, New South Wales 2006, Australia, 3Department of Psychology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, 4Center for Neural Science, New York University, New York, New York 10003, and 5Section of Comparative Medicine and Department of Neurobiology, Yale School of Medicine, New Haven, Connecticut 06520
The impact of Acehnese respect to customization, corporate reputation and airline service quality to switching barriers and customer loyalty: A study of airline customers in Indonesia

This study aimed to observe the impact of Acehnese Respect to Customization, Corporate Reputation and Airline Service Quality to Customer Loyalty with Switching Barriers as a mediating variable. The finding of this study would very use full to enrich the references how ethnical culture factor will also have a contribution to developing customer loyalty among airlines customers. Questionnaires distributed in the International Airport of Indonesia with Acehnese Ethnic segment as its primary target respondents. This survey was using probability sampling techniques to define its sample and respondents. Data were collected and then be analyzed using covariance Based SEM, AMOS. Hypothesis test results proved that there was a positive and significant influence among four variables examined in the study, both directly and indirectly. Although all the independent variables affect Customer Loyalty as dependence variable either directly or indirectly, but a more powerful influence given by variable of Airline Service Quality, compared to four other variables. This is shown by the coefficient numbers on the arrows leading to Customer Loyalty of 0.60 which is the highest coefficient compared to coefficients from other variables. Among the indicators that make up the Airline Service Quality, the indicator "Very friendly cabin crew service and ground staff” has the highest value with a score of 0.843. So this indicator was also played significant role to increase the Customer Loyalty of airline industry in Indonesia.
Angioedema induced by cardiovascular drugs: new players join old friends

During the last years, two new cardiovascular drug classes, namely inhibitors of DPP IV or neprilysin, have been developed. In both cases, there is clinical evidence for their potential to induce angioedema as known already from blockers of the renin–angiotensin–aldosterone system (RAAS). The majority of angioedema induced by DPP IV inhibitors occurs during concomitant treatment with ACEi and is therefore likely mediated by overactivation of bradykinin type 2 receptors (B2). In striking contrast, the molecular pathways causing angioedema induced by neprilysin inhibitors, that is, sacubitril, are unclear, although a contribution of bradykinin appears likely. Nevertheless, there is no clinical evidence suggesting that inhibition of B2 might relieve the symptoms and/or prevent invasive treatment including coniotomy or tracheotomy in angioedema caused by these drugs. Therefore, the risk of angioedema should always be considered, especially in ambulatory care situations where patients have no rapid access to intensive care.
Effects of seed magnetic fields on magnetohydrodynamic implosion structure and dynamics

The effects of various seed magnetic fields on the dynamics of cylindrical and spherical implosions in ideal magnetohydrodynamics are investigated. Here, we present a fundamental investigation of this problem utilizing cylindrical and spherical Riemann problems under three seed field configurations to initialize the implosions. The resulting flows are simulated numerically, revealing rich flow structures, including multiple families of magnetohydrodynamic shocks and rarefactions that interact non-linearly. We fully characterize these flow structures, examine their axi- and spherisymmetry-breaking behaviour, and provide data on asymmetry evolution for different field strengths and driving pressures for each seed field configuration. We find that out of the configurations investigated, a seed field for which the implosion centre is a saddle point in at least one plane exhibits the least degree of asymmetry during implosion.
Profiling the chemical content of Ficus lyrata extracts via UPLC-PDA-qTOF-MS and chemometrics

This study attempts to elucidate the secondary metabolite profiles of Ficus lyrata leaves and fruits grown in Egypt. Non-targeted metabolite profiling via ultra performance liquid chromatography (UPLC)-qTOF-MS was used to identify various chemical classes in F. lyrata fruits and leaves (i.e. flavonoids, phenolic acids and fatty acids) analysed by chemometrics. A total of 72 metabolites were evaluated via a UPLC-qTOF-MS-based metabolomic study. Seventeen flavonoids were characterised and tentatively identified with the main constituents being catechins/procyanidins, O- and C-linked flavonoid glycosides. The major procyanidins were dimers and trimers comprising (epi)catechin and (epi)afzelechin units, whereas the predominant flavones were C-glycosides of luteolin and apigenin. Aside from these major flavonoid classes, a group of benzoic acids, caffeoylquinic acids, fatty acid and sphingolipids were also annotated. This study provides the most complete map for polyphenol distribution in F. lyrata leaves and fruits and the basis for future investigation of its fruits nutritional value or possible nutraceutical uses.
MinD and role of the deviant Walker A motif, dimerization and membrane binding in oscillation

The ATPase activity of MinD is required for it to oscillate between the ends of the cell and spatially regulate cell division in Escherichia coli. It is a member of a functionally diverse subgroup of ATPases which are involved in activities ranging from nitrogen fixation (NifH) to plasmid segregation (ParA). All members of the subgroup have a deviant Walker A motif which contains a conserved ‘signature’ lysine that characterizes this subgroup. In the NifH homodimer the signature lysines make intermonomer contact with the bound nucleotides indicating a role in ATP hydrolysis. ATP binding to NifH leads to formation of an active dimer that associates with a partner that is also a dimer. Because ATP hydrolysis is coupled to formation of the complex, the complex is only transient. In the presence of ATP MinD binds MinC and goes to the membrane, however, the ATPase is not stimulated and the complex is stable. Subsequent interaction of this complex with MinE, however, leads to ATPase stimulation and release of the Min proteins from the membrane. The sequential interaction of MinD with these two proteins, which is dictated by the membrane, is critical to the oscillatory mechanism involved in spatial regulation of division.
The Determinants of Commercial Bank Profitability in Vietnam

This study investigates the determinants of profitability for Vietnamese banks between 2005 and 2015 using system generalized method of moments. The findings show the persistence of profits over time. More x-efficient banks appear to be more profitable, supporting the efficient-structure hypothesis. The same is true for banks with greater lending specialization; for those with lower liquidity risk; for more-diversified banks; for listed banks and smaller banks. Interestingly, the findings demonstrate that a less concentrated banking system improves bank profitability and profits tend to persist over time, suggesting the influence of government intervention in explaining bank performance in Vietnam.
Firefly Synchronization with Asynchronous Wake-up

This paper considers biologically-inspired synchronization algorithms for a model with primitive communication and asynchronous wake-up. Existing averaging-style algorithms for synchronization implicitly require a coherent round structure to guarantee convergence. We argue that this assumption is too strong in a distributed setting, and thus investigate the synchronization problem assuming nodes wake up asynchronously. Our preliminary results show that, under some assumptions, it is possible to approximate the properties of a coherent round structure given asynchronous wake-up, and leverage this observation to achieve synchronization in this setting. Achieving general solutions remains an interesting open question.
Parallel polyphase filtering for pulse shaping on high-speed optical communication systems

The requirement of higher data rates motivates the adoption of high-order modulations and pulse shaping in optical systems. This paper proposes an efficient architecture for FPGA-based parallel fractional sample rate conversion that has an optimum computational cost. The architecture supports non-integer oversampling factors, which allow increased flexibility when compared to schemes limited to adopting one or two samples per symbol, for example. The presented example is evaluated for a spectrally-efficient 400G optical supper-channel (three sub-channels with 16-QAM modulation) with different pulse shaping filter implementations using an FPGA working with a clock of 156.25 MHz. The results also illustrate the impact of the pulse shaping when a non-integer oversampling is adopted.
Adsorption Efficiency of a New Adsorbent Towards Uranium and Vanadium Ions at Low Concentrations

Abstract A new type of fibrous adsorbent with excess amidoxime groups was synthesized by radiation-induced graft polymerization. Glycidyl methacrylate (GMA) was first radiation‐grafted on polyethylene‐coated polypropylene nonwoven fabrics and chemically modified with 3,3′-iminodipropionitrile [NH (–CH2–CH2–CN)2] (IDPN), which was further reacted with hydroxylamine to obtain graft chains containing two amidoxime groups per graft repeating units. The adsorption properties of this new adsorbent for uranium (U), vanadium (V), lead (Pb), copper (Cu), and cobalt (Co) ions at low concentrations (3.3–1000 ppb) were investigated by a batch process. The adsorbent showed enhanced adsorption capacity for uranium and vanadium ions. In adsorption studies from a mixture of metal ions in aqueous solutions, the adsorbent showed selectivity for metal ions in the following order: V > U ≫ Cu ≥ Pb ≫ Co. The selectivity of the adsorbent was assessed by determining the distribution coefficient D, of the metal ions studied. The U and V ions were shown to be up to six times more selectively adsorbed onto the new adsorbent than the other metal ions.