Miracle-dz/UniFAR-FTUs huggingface dataset:
Role of Membrane Cholesterol in Modulating Actin Architecture and Cellular Contractility

Atherosclerosis is a chronic inflammatory process that initiates with accumulation of apolipoprotein B containing lipoproteins (LPs) in the subendothelium (intima), espe cially in areas where the laminar flow is disturbed. LP retention triggers an inflammatory response leading to activation of endothelial and vascular smooth muscle cells that cul minates with recruitment of leukocytes. Atherosclerosis is the leading cause of vascular disease worldwide being its major clinical manifestations ischemic heart disease, isch emic stroke, and peripheral arterial disease. Even though a lot has been done to unravel the role of turbulent flow and mechanotransduction for atherosclerosis development, little is known about the role of plasma membrane (PM) cholesterol in this process. This chapter is going to be focused on exploring what has been done so far to decipher the role of PM cholesterol in regulating actin architecture, cellular mechanical properties, and cellular contractility in muscle and nonmuscle cells.
Effective reduction of primary dysmenorrheal symptoms through concurrent use of n-3 fatty acids and Rosa damascena extract (RDE)

Background: Primary dysmenorrhea (PD) is characterized by painful cramps of lower abdomen without abnormal pelvic pathology. PD begins some hours before or simultaneously with the onset of menstrual bleeding. Objectives: The purpose of this study was to investigate the effects of separate and concurrent supplementation of fish oils (FO) containing n-3 fatty acids and Rosa Damascena extract (RDE) on PD symptoms. Methods: In this double blind clinical trial in 2015, through convenience sampling, 105 university students with primary menstrual pain in most recent years, without abnormal pathology, and with moderate/severe dysmenorrheal symptoms according to visual analogue scale (VAS) were randomly assigned into one of four groups: 1. FO 1000 mg/day (n=26), 2. RDE 1000 mg/day (n=27), 3. FO and RDE concurrently, with the same dose (n=27), and 4. Control group (n=25). All measurements were performed three times, at the beginning, 30 th day, and 60 th day. Symptoms including nausea, vomiting, diarrhea, bloating, cramp, low back pain, headache, fatigue, anxiety, sweat, weakness, dizziness, drowsiness, and feeling cold were measured by VAS. Results: After 2-month treatment, supplementation with RDE significantly reduced severity of bloating (p<0.001) and sweat (p<0.001), but FO supplementation had no significant effect on PD symptoms. The concurrent use of FO and RDE significantly decreased severity of diarrhea (p=0.038), weakness (p<0.001), dizziness (p=0.003), and feeling cold (p=0.049). Conclusion: Our results suggest that the concurrent supplementation of omega-3 fatty acids and RDE could be more effective than their separate use in decreasing PD symptoms; however, larger trials are warranted to confirm these preliminary findings.
Return to Sport after Anterior Cruciate Ligament Reconstruction: A Literature Review

Anterior Cruciate Ligament (ACL) injuries are very common in an athletic population. An ACL injury is a major injury, with a devastating effect on the athletes’ sports participation. The goal after an ACL surgery is to return to sport, and ideally to the same level of sports participation as prior to the injury. In the literature, reports of returning to competitive sports at the same pre-injury level are rather low and differ from 33 to 63%. General consensus exists that a successful return to sports relies heavily on the rehabilitation program. Today it is generally believed that muscle strength, neuromuscular control and fear of re-injury are critical factors for a successful return to sports and must be considered as imperative in the rehabilitation program. In this review, these parameters are described and based upon that, some criteria for a successful return to sport are provided. Indeed, research has proven that a good rehabilitation program, with demanding criteria can reduce the risk of re-injury, prepare the athlete to perform at the same pre-injury level and secure the safe transition of the player from physiotherapy to normal training. More research is needed in order to determine exact criteria for the return to sport. This evidently will lead to a higher percentage of successful return to sport.
Tidally induced oscillations and orbital decay in compact triple-star systems

We investigate the nature of tidal eects in compact triple-star systems. The hierarchical structure of a triple system produces tidal forcing at high frequencies unobtainable in binary systems, allowing for the tidal excitation of high frequency pmodes in the stellar components. The tidal forcing exists even for circular, aligned, and synchronized systems. We calculate the magnitude and frequencies of three-body tidal forcing on the central primary star for circular and coplanar orbits, and we estimate the amplitude of the tidally excited oscillation modes. We also calculate the secular orbital changes induced by the tidally excited modes, and show that they can cause signicant orbital decay. During certain phases of stellar evolution, the tidal dissipation may be greatly enhanced by resonance locking. We then compare our theory to observations of HD 181068, which is a hierarchical triply eclipsing star system in the Kepler eld of view. The observed oscillation frequencies in HD 181068 can be naturally explained by three-body tidal eects. We then compare the observed oscillation amplitudes and phases in HD 181068 to our predictions, nding mostly good agreement. Finally, we discuss the past and future evolution of compact triple systems like HD 181068.
A genie in a bottle?: Globalisation, competition and inflation

Declining inflation in many countries over the past few decades at the same time as rising global competition has led to a debate on the importance of globalisation for domestic inflation. This paper explores the implications of global value chain (GVC) integration and market contestability for inflation using a range of industry-level and micro-data sources. We provide evidence that rising participation in GVCs has placed downward pressure on producer price inflation, by increasing the ability of firms to substitute domestic inputs with cheaper foreign equivalents. We investigate the channels, which suggests that increased GVC participation contributed to lower inflation via downward pressures on unit labour costs – by raising productivity and reducing wages – in the importing country, especially when low-wage countries are integrated in supply chains. We then present industry-level evidence to support the conjecture that a higher level of GVC integration dampens producer price inflation by accentuating the impact of global economic slack on domestic inflation. However, we also find an increasing trend in mark-ups, suggestive of rising market power, particularly in services sectors. Thus, looking forward, there is a risk that stalling globalisation since the crisis, coupled with stronger aggregate demand and declining market contestability, could lead to inflationary pressures in the medium term, thereby letting the inflation genie out of the bottle.
Calibrating HRM and Marketing Practices for Job Satisfaction: The Role of Internal Marketing and Internal Market Orientation

Services sector is characterized by greater interactions among employees and the customers of an organizations. Satisfied employees or internal customers can lead to satisfied external customers; thus suggesting the need for calibrating HRM with marketing practices. The higher education sector in Pakistan is no different where increasing competition for quality students and rankings is putting strain on the organizations and their employees, especially the faculty. Internal marketing (IM) that attunes HRM approaches with a marketing paradigm is emerging as a new management tool. It focuses on addressing internal customers’ needs in order to improve organizational performance vis-a-vis external customers. Literature suggests that IM can be achieved through internal market orientation (IMO). Also, the more an organization focuses on IM, the more its employees will be satisfied with their jobs. This paper studies the impact of IMO on IM, the impact of IM and IMO on job satisfaction and the mediating role of IM between IMO and job satisfaction within the context of the higher education sector. For this purpose a quantitative study on 10 different universities and institutes having a management department was conducted. Faculty members and representatives of senior management were targeted for data collection. Results show positive relationships between IMO, IM and job satisfaction; thus extending the theory to the higher education context. From the results it can be concluded that IM is influenced by IMO and is as important for service organizations as external marketing. It further strengthens the notion that without satisfied internal customers in the form of faculty, higher education institutions may struggle to improve their quality, rankings, and financial performance
Cardiovascular Disease Risk Profile in Japanese Midlife Migraineurs

Background: Migraine is a common disabling disorder. A significant association between migraine and cardiovascular disease (CVD) has been reported in European and North American population. Little is known about CVD risk factors in Asian migraineurs. We aimed to clarify CVD risk profile of midlife migraineurs in Japan. Methods: A total of 596 subjects (409 women and 187 men) were diagnosed as migraine with aura (MA) and without aura (MO), according to the ICHD-II criteria. CVD risk factors were analyzed on body mass index, west circumference / height, smoking index , blood pressure (BP), serum l ipid levels , f asting blood sugar, hemoglobin A 1C , C-reactive protein, and a family history of CVD or stroke. Those factors were compared between migraineurs and 599 healthy controls matched by age and sex. Results: Mean age (SD) of migraineurs was 44.6 (9.4) years, 44.3 (9.4) in women and 45.2 (9.3) in men. Mean duration of migraine (SD) was 16.7 (11.4) years, 18.7 (12.2) in women and 13.3 (9.1) in men. Frequency and score of migraine attacks were higher significantly in women compared to men (P less than 0.01). As compared to controls, systolic and diastolic BP was significantly increased in female and male migraineurs (P less than 0.01). High-density lipoprotein cholesterol was decreased (P less than 0.01), and total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) were increased in sera of female and male migraineurs (P less than 0.01). Serum triglyceride levels were higher in male migraineurs (P less than 0.01). Migraineurs had higher frequency of relatives with CVD or stroke (P less than 0.01). With respect to migraine subtypes, MA and MO sufferers significantly elevated BP (P less than 0.05) and serum levels of TC and LDL-C (P less than 0.01). Conclusions: The present study indicated unfavorable CVD risk factors of BP, serum lipid levels and a family history of CVD or stroke in middle-aged migraineurs. The similarity of CVD risk profile was first confirmed between Japanese and Western migraineurs. doi:10.4021/jnr82w
NUTRIENT REDUCTION DURING TREATMENT OF WASTE WATER; A CASE STUDY OF KOTRA SEWAGE TREATMENT PLANT, BHOPAL (INDIA)

International studies on the nitrates and phosphates in the surface waters of various water bodies have drawn the attention of scientists around the globe. The nitrate and phosphate are two important constituents that immensely help in the growth of the plants where they present. Their presence in water bodies will excessively promote the growth of aquatic weeds and polluting our water resources. In present study sample of waste water from different stages of Kotra Sewage Treatment Plant (STP) situated at Bhopal, Madhya Pradesh were analyzed quarterly for nitrate & phosphate from March 2012 to February 2013 by using standard methods. The result obtained indicates that the sewage treatment plant was effective in reducing nitrate & phosphate concentration and treated water can be used for secondary purposes like industrial cooling, gardening, irrigation, domestic activities etc.
The VLT LBG redshift survey – V. Characterizing the z = 3.1 Lyman α emitter population

We present a survey of z ∼ 3 Lyα emitters (LAEs) within the fields of the VLT Lyman break galaxies (LBG) redshift survey. The data encompass five independent survey fields co-spatial with spectroscopic LBG data and covering a larger total area than previously analysed for LAE number counts and clustering. This affords an improved analysis over previous work by minimizing the effects of cosmic variance and allowing the cross-clustering analysis of LAEs and LBGs. Our photometric sample consists of ≈600 LAE candidates, over an area of 1.07 deg2, with equivalent widths of ≳65 A and a flux limit of ≈2 × 10−17 erg cm−2 s−1. From spectroscopic follow-up, we measured a success rate of 78 ± 18 per cent. We find the R-band continuum luminosity function to be ∼10 times lower than the luminosity function of LBGs at this redshift, consistent with previous studies. Exploiting the large area of the survey, we estimate the LAE auto-correlation function and find a clustering length of r0 = 2.86 ± 0.33 h−1 Mpc, low compared to the z ∼ 3 LBG population, but somewhat higher than previous LAE measurements. This corresponds to a median halo mass of MDM = 1011.0±0.3 h−1 M⊙. We present an analysis of clustering length versus continuum magnitude and find that the measurements for LAEs and LBGs are consistent at faint magnitudes. Our combined data set of LAEs and LBGs allows us to measure, for the first time, the LBG–LAE cross-correlation, finding a clustering length of r0 = 3.29 ± 0.57 h−1 Mpc and a LAE halo mass of 1011.1±0.4 h−1 M⊙. Overall, we conclude that LAEs inhabit primarily low-mass haloes, but form a relatively small proportion of the galaxy population found in such haloes.
A stability result for small stationary solutions of a class of nonlinear Dirac equations

Nous presentons, pour un operateur de Dirac, des estimations de Strichartz et de regularite au sens de Kato. Puis nous nous interessons a une classe d’equations de Dirac non lineaires. Celle-ci est associee a un operateur de Dirac n’ayant qu’une seule valeur propre, dont la multiplicite est deux. Nous construisons une petite variete d’etats stationnaires et, appliquant nos estimations, nous enoncons un theoreme sur la stabilite asymptotique de ces etats.
Floristic composition and zonation of seaweeds on Zabargad Reef (Red Sea, Egypt)

Composition, dominance, distribution and zonation of seaweeds were investigated, using line-transect technique,in three sites of varied water activity on Zabargad reef during November 1994. Fifty-four taxa included 16 green,13 brown and 25 red macroalgae were identified, adding four new records for the Red Sea. The flora appearsrich and diverse, composed of filamentous, turf-forming, fleshy sac, foliose, erect shoot, and coralline forms. Itshowed a geographic distribution pattern similar to that of the Indo-Pacific.The seaweed vegetation appears heterogeneous, having a dissimilar construction at each side of thereef. It showed a conspicuous zonation, revealing six zones related in general to reef topography, watermovement and in a lesser extent to grazing and nutrient enrichment. The intertidal zone had a marked reducedflora due to exposure to air during low tide, and mobility of coral sand. Reef flat was the richest in speciescomposition and dominance, as it lies in a shallow, well-illuminated, and less fluctuated subtidal region. Peculiarwas the presence of high species dominance in strong surf on the windward reef crest. The reason for this is thatthe crest is extensively eroded, rich in crevices and fissures within which the algae hideaway from wave action.Moreover, strong rhizoids, dwarfing of thalli, crustose morphologies, growing in adherent to substrata weresome modifications allowing algae to persist in strong surf.
Distribution and Abundance of Canadian Polar Bear Populations: A Management Perspective

Seasonal fidelity to relatively local areas and natural obstacles to movements allow the range of polar bears ( Ursus maritimus ) in Canada to be divided into 12 relatively distinct populations. These divisions are not the only ones possible, and may not be the best ones; however, they were consistent with observed movements of marked bears. The average area of sea ice (mainly annual ice) that constitutes polar bear habitat for populations within and shared with Canada was estimated to total approximately 3.1 million sq km in April each year. The density estimates of polar bears ranged between 1.1 and 10.4 bears per 1000 sq km with a weighted mean of 4.1 bears per 1000 sq km. The sum of polar bear population estimates within or partially within Canada is approximately 12 700. However, the available data were insufficient to quantify the precision and accuracy of some population estimates. Key words: abundance, Arctic, bear, distribution, polar bear, population, Ursus maritimus
THE MASTER TEACHER PROGRAM: A CASE FOR THE EVOLVING PRACTITIONER*

In this qualitative study I explored six CEGEP teachers’ perspectives on teaching and learning over a twoyear period, as they completed the first four courses in a professional development program, the Master Teacher Program (MTP). Repeated, semi-structured interviews were analyzed, using the dual processes of categorizing and connecting (Maxwell & Miller, 2008). Results converged to reveal four patterns and three major dimensions. The four patterns that emerged described a process of evolution from teacher to learner-centeredness. I used the four metaphors of awakening, stretching, exercising, and shaping to represent these four patterns. Three major dimensions related to teacher perspectives were also evident. The participants reported that they had become more aware of the learner and the learning process, more intentional in curriculum planning and teaching, and that they acquired greater self-knowledge, and in particular, a better sense of identity as teacher professionals. Reflection on practice over time emerged as the major factor underlying changes in perspectives.
Understanding the effect of Bathymetry on the Marine Controlled Source Electromagnetic Method using Electromagnetic Streamlines

Summary Understanding the impact of bathymetry can be a critical in application of the marine controlled source electromagnetic methods. Electromagnetic field strength and direction can be affected by small changes in water column depth. The bathymetry, the air-water interface and sub-surface resistivity variations will all contribute to any single electromagnetic measurement. In such complex geo-electric settings a deeper understanding of how and where each feature is expressed in the electromagnetic response is required. We compute the electromagnetic fields for a model with complex bathymetry and a hydrocarbon target. We compute the response with and without hydrocarbon to investigate the effect of bathymetry. A 2.5D finite element algorithm was used to forward model the MCSEM response. The interaction of the electromagnetic fields with the target and the bathymetry can be appreciated by viewing electric and magnetic streamlines. A key benefit of using streamlines is that they quickly show where the electric or magnetic fields would be most strongly altered by the target or alternatively by bathymetry. This aids both interpretation and survey design.
Between Resistance and Resilience. How Do Italian Solidarity Purchase Groups Change in Times of Crisis and Austerity

This Paper deals with the current transformations of Solidarity Purchase Groups (SPGs) in Italy. We particularly wonder if and eventually how the economic crisis and austerity policies have affected SPGs. Through an approach based on the literature on political consumerism and social movements, six hypotheses are proposed: ‘less economic resources, less SPGs,’ ‘cultural path dependency,’ ‘increased op-portunities,’ ‘isomorphism,’ ‘civic traditions,’ and ‘resilience. ’ Empirical data focus on Italian and Tuscan SPGs, by both articulating different research methods and focalizing on different levels. Although our work has only an explorative aim, our analysis shows that the amount of available economic resources cannot per se lead to a satisfying understanding of the evolution of SPGs. Hypotheses based on culture and politi-cal processes seem to be more promising and can point to the resilience capacity of those groups. Post-materialistic values resulting from economic well-being might have produced organized practices of political consumerism. However, once political consumerism gets structured—this is our tentative argument—not only does it resist to external shocks but also it transforms itself and adapts to the new conditions imposed by crises, that is, it becomes ‘resilient. ’ The ‘resilience hypothesis’ applied to SPGs nevertheless has to face some social cleavages.
Altering the Dutch labour market

Questioned is whether subsidized labour can increase social welfare compared to current redistribution policies. Three main policies of the Dutch welfare state - the assistance benefit, statutory minimum wage, and legislation favouring unions - are discussed. The assistance benefit causes wages to rise and unemployment to grow. Also, job-searchers put less effort in their search. The statutory minimum wage and labour unions favouring legislation causes wages to be above market-clearing levels, thus causing higher levels of unemployment. Due to higher unemployment levels among the low-skilled these policies do not achieve redistribution (efficiently). An alternative of subsidized labour is given. Such subsidy will improve employment, while government expenditure will not rise considerably. It provides an incentive to have a job, and assures a minimum income. The Earned Income Tax Credit (EITC) of the U.S.A. is given as an example of such a subsidy. Several models are provided to demonstrate the positive effect on social welfare, while redistributing income.
A Test of Market Efficiency based on Share Repurchase Announcements

Capital markets play a central role in resource allocation in an economy. They must be efficient for optimal resource allocation. This study tests market efficiency using event study method. The results, based on share repurchase announcements (event), confirm some earlier findings and refute others. The results can be explained through behavioural models of under and over reaction. Sub sample analysis shows opposite results to existing literature. There is some evidence that market responds selectively to share repurchase announcement of firms depending upon their recent performance-firms with positive earnings growth in the year prior to repurchase announcement perform better than firms with negative earnings growth. Keywords: Market Efficiency, Share Repurchase, Event Study, Efficient Market Hypothesis