Miracle-dz/UniFAR-FTUs huggingface dataset:
Encephalocraniocutaneous Lipomatosis: Clinical Spectrum of Systemic Involvement

Abstract: Encephalocraniocutaneous lipomatosis is a rare neurocutaneous syndrome with involvement of ectomesodermal tissues. Unilateral lipomatous hamartomas of the scalp and eyes are the hallmarks of this disorder. Associated findings are extremely variable, ranging from minor abnormalities to severe, debilitating disease. We report two unrelated Brazilian patients with encephalocraniocutaneous lipomatosis, one presenting with the full‐blown spectrum of cutaneous, ocular, and central nervous system manifestations, and the other with minor extracutaneous manifestations after a 5‐year follow‐up period.
E-learning model for teaching programming language for secondary school students in Indonesia

This paper aimed to propose e-Learning model as an educational concept to teach introduction to programming for secondary school students. The objective of the model is to determine the components involved by applying collaborative learning in e-Learning, to enhance students' motivation and understanding in the subject Information and Communication Technology/ICT, specifically in topic introduction to programming. The model is developed because the need of fast-paced informatics competencies as it mentioned in Indonesians Secondary School 2006 Curricula. In addition, ICT subject is considered as attractive yet a difficult subject to learn. Therefore, approaches and methods to teach in ICT subject should be designed and delivered carefully.
Disturbances of ionic equilibrium of intracellular and extracellular electrolytes in patients with tuberculous meningitis.

Diminished concentrations of chloride and sodium in plasma are frequently found in patients with acute bacterial infections (1). This type of deviation from the normal electrolyte pattern is also encountered in an occasional patient with pulmonary tuberculosis and has received special attention because of the problem of differential diagnosis of Addison's disease (2-5). By the use of methods of assessment of adrenocortical function which do not depend upon determinations of serum electrolytes it has been shown that hypochloremia and hyponatremia may be present in patients with tuberculosis without evidences of adrenal insufficiency (5). Reductions of the serum chloride and sodium values are consistently found in children with tuberculous meningitis. In the past this observation
Thyroid Disease Diagnosis using Genetic Algorithm and Neural Network

Nowadays, with advancement of technology and scie nce and expansion of computer usage in high-tech calculations, especially in the field of medicine, intelligence systems and in particular Neural Networks are becoming of signific ant importance in automatic diagnosis and prognoses of different diseases. This paper present s the diagnosis of thyroid diseases using Neural Networks. The genetic algorithm was used to find the optimum network structure with high classification accuracy. The experimental resu lts presented for different proportions of training/testing groups show a high classification accuracy and convergence in rates. The overall accuracy is 100% for training and in range between 96% and 98% for testing. The neural networks are simulated using MATLAB. While thyroid disease datasets are taken from UCI machine learning dataset.
[Efficacy of hirudin in treating immunoglobulin A nephropathy with hematuria: a randomized controlled trial].

OBJECTIVE To investigate the curative effects and side effects of hirudin in treating immunoglobulin A nephropathy (IgAN) with hematuria and minimal proteinuria in a short-term. METHODS Two hundred and sixty-two histologically confirmed cases of IgAN with hematuria and minimal proteinuria from 1998 to 2007 were randomly divided into hirudin-treated group (peroral administration of Maixuekang capsules) and dipyridamole-treated group (peroral administration of dipyridamole). In the two groups, contrast analysis of conformation and counts of erythrocytes in urine, urine protein quantitation in 24 hours, levels of serum creatinine (Scr) and creatinine clearance rate (Ccr), blood lipid, five items of blood clotting and side effects was performed. RESULTS After six-month treatment, the anisotrophy rate and the counts of erythrocytes in urine, and the urine protein quantitation in 24 hours in hirudin-treated group were decreased distinctly as compared with pre-treatment (P<0.01) and dipyridamole-treated group (P<0.05). On the other hand, Ccr was increased obviously in hirudin-treated group as compared with pre-treatment and dipyridamole-treated group (P<0.01). The blood lipid was also ameliorated in hirudin-treated group, but there was no significant difference. The anticoagulation effect of hirudin was better than dipyridamole (P<0.01). Efficacy assessment showed that the total response rate, complete remission rate and predominance remission rate in hirudin-treated group were higher than those in dipyridamole-treated group. Few side effects were found in both groups, and the rate of adverse reaction in gastrointestinal tract was lower in hirudin-treated group as compared with that in dipyridamole-treated group (P<0.05). CONCLUSION Compared with dipyridamole, hirudin has superiority in kidney protection and decreasing the anisotrophy rate, counts of erythrocytes in urine and the urine protein.
Social Functioning Difficulties in ADHD: Association with PDD Risk

Although social difficulties are a common feature of Attention-Deficit Hyperactivity Disorder (ADHD), little is known about the diversity of social problems, their etiology, or their relationship to disorders of social behavior, such as autism or Pervasive Developmental Disorder (PDD). In 379 children and adolescents with ADHD, social functioning was assessed using the Child Behavior Checklist (Achenbach, 1991). Factor analysis and structural equation modeling revealed two factors that we labeled Peer Rejection and Social Immaturity. A factor reflecting `PDD risk' was defined from eight items of a separate screening instrument for PDD and examined for its association with these two social factors. There was a significant association with both factors, but the association was much stronger for the Social Immaturity (Standardized Beta [β ] = .51) than Peer Rejection (β = .29) factors. Social Immaturity was also associated with a greater number of hyperactive symptoms while high Peer Rejection was associated with increased aggression and lower IQ in the ADHD children.
Calmodulin kinase and a calmodulin‐binding ‘IQ’ domain facilitate L‐type Ca2+ current in rabbit ventricular myocytes by a common mechanism

1 Ca2+‐calmodulin‐dependent protein kinase II (CaMK) and a calmodulin (CaM)‐binding ‘IQ’ domain (IQ) are both implicated in Ca2+‐dependent regulation of L‐type Ca2+ current (ICa). We used an IQ‐mimetic peptide (IQmp), under conditions in which CaMK activity was controlled, to test the relationship between these CaM‐activated signalling elements in the regulation of L‐type Ca2+ channels (LTCCs) and ICa in rabbit ventricular myocytes. 2 A specific CaMK inhibitory peptide nearly abolished ICa facilitation, but the facilitation was ‘rescued’ by cell dialysis with IQmp. 3 IQmp significantly enhanced ICa facilitation and slowed the fast component of ICa inactivation, compared with an inactive control peptide. Neither effect could be elicited by a more avid CaM‐binding peptide, suggesting that generalized CaM buffering did not account for the effects of IQmp. 4 I Ca facilitation was abolished and the fast component of inactivation eliminated by ryanodine, caffeine or thapsigargin, suggesting that the sarcoplasmic reticulum (SR) is an important source of Ca2+ for ICa facilitation and inactivation. IQmp did not restore ICa facilitation under these conditions. 5 Engineered Ca2+‐independent CaMK and IQmp each markedly increased LTCC open probability (Po) in excised cell membrane patches. The LTCC Po increases with CaMK and IQmp were non‐additive, suggesting that CaMK and IQmp are components of a shared signalling pathway. 6 Both CaMK and IQmp induced a modal gating shift in LTCCs that favoured prolonged openings, indicating that CaMK and IQmp affect LTCCs through a common biophysical mechanism. 7 These findings support the hypothesis that CaMK is required for physiological ICa facilitation in cardiac myocytes. Both CaMK and IQmp were able to induce a modal gating shift in LTCCs, suggesting that each of these signalling elements is important for Ca2+‐CaM‐dependent LTCC facilitation in cardiac myocytes.
Molecular cloning of cDNA species for rat and mouse liver α-methylacyl-CoA racemases

cDNA species coding for α-methylacyl-CoA racemase were cloned from rat and mouse liver cDNA libraries and characterized. The rat liver λgt11 cDNA expression library was screened with anti-racemase IgG [Schmitz, Albers, Fingerhut and Conzelmann (1995) Eur. J. Biochem. 231, 815–822]. Several fulllength clones were obtained that contained an open reading frame of 1083 bp, coding for a protein of 361 amino acid residues with a predicted molecular mass of 39679 Da. The sequences of three peptides that were isolated by HPLC from a tryptic digest of purified rat liver racemase fully matched the cDNA-derived amino acid sequence. The cDNA coding for mouse racemase was
Are memories for sexually traumatic events “special”? A within-subjects investigation of trauma and memory in a clinical sample

According to a long-standing clinical tradition, sexually traumatic experiences are processed and recalled differently from other experiences, often leading to memory impairment. In this study, we compared the characteristics of traumatic memories for sexual violence and two other types of emotional experiences. N=44 women recruited from a local sexual trauma agency were asked to recall and describe three autobiographical events: sexual abuse/assault, a non-sexual trauma, and a positive emotional event. The characteristics of the three memory types were compared on both subjective and objective measures. Further, the potential influences of level of traumatic impact and dissociation were assessed. Results indicated that memories for sexual trauma were not impaired or fragmented relative to other memories. Instead, memories for sexual trauma were associated with a remarkably high level of vividness, detail, and sensory components. Further, high levels of traumatic impact were not associated with memory impairment. Implications for the ongoing traumatic memory debate are discussed.
Rosenberg Self-Esteem Scale Greek Validation on Student Sample

This paper presents the standardization of the Rosenberg Self-Esteem Scale (RSES) in the Greek population. Self-esteem is defined as the positive or negative reflection that the individual has for himself/herself and the belief of being able to cope with the basic challenges of life. The RSES was completed by university students with a mean age of 19. Along with the RSES we administered the Health Locus of Control Scale, the Perceived Stress Scale (PSS), the Stress and Personality Self Test and the self-esteem questionnaire (Darviri & Varvogli). The results on the reliability and validity of the RSES were satisfactory as the internal reliability index crombach a was . 80 and the RSES had positive statistical significant relationship with the second questionnaire of self-esteem. We also found statistically significant relationships with stress levels, health locus of control and personality types. It seems that when people attribute their good health to others, they have increased self-esteem in relation to people who attributed their good health to themselves. Furthermore our study showed that women have higher levels of self-esteem than men, an opposite outcome to the one of previous validations. The RSES Greek version is a tool that can be used for the measurement of Self-Esteem in the Greek Population.
DEATH OF A SPOUSE: ILLUSORY BASIC ASSUMPTIONS AND CONTINUATION OF BONDS

Recently psychologists have questioned the traditional model of grief, arguing that the continuation of bonds with the deceased spouse is generally adaptive. Continuing bonds can be seen as attempts to cope with the loss of a spouse but also with the shattering of the normal illusory basic assumptions about the self,the world, and the future. At this time, however, scholarship has provided few concepts to understand how continuing bonds and illusions express adaptive or maladaptive forms of grief. Therefore, the purpose of this article is to identify, in the context of the illusory basic assumptions, the circumstances by which the bond with the deceased is adaptive or maladaptive. So Epstein (1980) distinguished between higher order postulates and lower order postulates. Higher order postulates are an abstract form of schemas, or generalized theories about the self, the world, and the future, that are resistant to changes. On the other hand, lower order postulates are a concrete form of schemas normally flexible and responsive to the changes in the reality of the new situation. On the basis of this distinction, the author argues that higher order bonds or symbolic bonds are adaptive, whereas lower order bonds or concrete bonds are maladaptive.
Measurement of internal charge distribution of electric double layer capacitor by PEA method

In this study, electrolyte was injected into an electric double layer capacitor (EDLC) after degas treatment in vacuum and directly in air, respectively, and the internal charge distribution in the EDLC was examined by the pulsed electro acoustic (PEA) method. It was found that volume charge density in the case of injection of electrolyte after degas treatment in vacuum is about seven times compared with that injected directly in air. It was thought that sufficient electrolyte can be injected into the polarized microporous electrode by degas in vacuum and more electric charge can be saved. Moreover, the sound velocity in the material is examined. It has been understood that electrostatic capacity gradually increases with the rise of applied voltage. The electrostatic capacity was estimated by the PEA method and the energy conversion method, respectively. The results from two methods are in good agreement.
Supported depression self-care may prevent major depression in community-dwelling older adults with chronic physical conditions and co-morbid depressive symptoms

Self-care programs for depression use educational and cognitive-behavioral techniques (e.g. written information, audiotapes, videotapes, computerized, or group courses) to assist patients in the management of depressive symptoms (Morgan and Jorm, 2008). In the UK, these interventions are recommended as step 1 in a stepped care program for treating depression in primary care (National Institute for Health and Clinical Excellence, 2007). One meta-analysis suggests that supported self-care (self-care with coaching) is more effective than unsupported self-care (Gellatly et al., 2007).
Changes in nerve fiber numbers distal to a nerve repair in the rat sciatic nerve model

Changes in nerve fiber numbers distal to a nerve repair in the sciatic nerve of 48 rats were evaluated over a 1‐ to 24‐month period. The results of the morphometric evaluation in the sciatic nerve distal to the nerve repair demonstrated an increase in nerve fiber counts as early as 1 month following the nerve repair. The number of nerve fibers in the distal nerve was greatest at 3 months and did not return to normal levels until 24 months. The results of this study will influence the timing of experimental studies in which nerve fiber counts are critical for evaluation, and provides a better understanding of the clinical events occurring following nerve repair.
Anaesthetic considerations for endovascular abdominal aortic aneurysm repair ( EVAR )

ee front matter & 2008 acc.2008. 04.006 ing author. Tel. : +44 161 6 8027. ess: adam.pichel@cmm Summary Over the previous decade, the management of vascular disease has changed considerably. Abdominal aortic aneurysm can now be definitively treated by means of endovascular stenting. Though significant shortand long-term morbidity has been reported, this less invasive procedure is increasing in popularity and has been championed by some as an alternative option for high-risk patients who might otherwise be offered conservative management. We review the perioperative management of endovascular abdominal aortic aneurysm repair (EVAR) and cover the issues pertinent to anaesthetists. & 2008 Elsevier Ltd. All rights reserved.
Early Health Shocks, Intra�?Household Resource Allocation and Child Outcomes

An open question in the literature is whether families compensate or reinforce the impact of child health shocks. Discussions usually focus on one dimension of child investment. This paper examines multiple dimensions using household survey data on Chinese child twins whose average age is 11. We find that, compared with a twin sibling who did not suffer from negative early health shocks at ages 0-3, the other twin sibling who did suffer negative health shocks received RMB 305 more in terms of health investments, but received RMB 182 less in terms of educational investments in the 12 months prior to the survey. In terms of financial transfers over all dimensions of investment, the family acts as a net equalizer in response to early health shocks for children. We estimate a human capital production function and establish that, for this sample, early health shocks negatively affect child human capital, including health, education, and socioemotional skills. Compensating investments in health as measured by BMI reduce the adverse effects of health shocks by 50%, but exacerbate the adverse impact of shocks on educational attainment by 30%.
Beliefs, attitudes and self-use of Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy medicines among senior pharmacy students: An exploratory insight from Andhra Pradesh, India

Objectives: To assess the beliefs, attitudes and self-use of Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy (AYUSH) medicines among senior pharmacy students. Methodology: This was a descriptive cross-sectional study conducted among pharmacy students in four pharmacy schools located in Andhra Pradesh in South India. This study was conducted from the August to September 2014. The study population included all pharmacy students enrolled in Doctor of Pharmacy, Bachelor of Pharmacy and Diploma in Pharmacy programs in studied pharmacy schools. The pretested AYUSH survey had 8 questions on AYUSH related beliefs and 8 question on AYUSH related attitudes. The survey also asked participants about AYUSH related knowledge, frequency of use of AYUSH and the reason for using AYUSH. The data analysis was performed using SPSS Version 20. Chi-square test and Mann-Whitney U-test were employed to study the association between the independent and dependent variables. Results: A total of 428 pharmacy students participated in the survey. 32.2% of the study population was females and 32.5% of the population resided in rural areas. Males were more likely to have positive beliefs about AYUSH when compared to females (odd ratio [OR] = 4.62, confidence interval [CI] = 2.37−8.99, P < 0.001). Similarly, students living in hostels were more positive in their beliefs about AYUSH compared with students living at home (OR = 2.14, CI = 1.12−4.07, P < 0.05). Students living in hostel also had a positive attitude about AYUSH use (OR = 1.74, CI = 1.03−2.93, P < 0.05). Conclusion: Pharmacy students held favorable attitude and beliefs about AYUSH use. This baseline survey provides important information about the pharmacy student′s perception about AYUSH. Further research is needed to explore the reasons that shape the pharmacy student′s beliefs and attitudes about AYUSH.
Botanical and Ethnoveterinary Surveys of Two Acacias ( Acacia raddiana and Acacia nilotica ) Exploited in Small Ruminant Rearing in Sahelian Area of Burkina Faso

In Burkina Faso, rural livestock farmers in arid and semi-arid areas rely heavily on woody plant resources such as Acacia nilotica and Acacia raddiana to satisfy the needs of small ruminant rearing. The assessment of the availability and the use of these two species are therefore essential to better manage them sustainably for their preservation. The survey carried out in the area showed that the questioned farmers exploited the leaves and pods of the two Acacia for the needs of the ruminants. 100% of the farmers exploit A. raddiana only for the feeding of small ruminants. However, A. nilotica was exploited for animal feed and health. The most commonly reported treatments are Foot and Mouth Disease (98.7%) followed by diarrhea (73.7%) and foot wounds (51.2%). In order to compare the results of the survey, a botanical inventory was carried out in the area and the results showed that A. raddiana is more available compared to A. nilotica. Also, other local species such as Faidherbia albida, Acacia senegal, Balanites aegyptiaca and Acacia siberiana are also exploited for the needs of small ruminant rearing in the study area. The most important constraints were excessive cutting, drought and overexploitation that negatively impact their survival. Data on these constraints provide the basis for a campaign to raise awareness among herders' communities to preserve these plants to sustainably improve the productivity of small ruminants and consequently farmer’s income.
The vitamin D receptor agonist elocalcitol inhibits IL‐8‐dependent benign prostatic hyperplasia stromal cell proliferation and inflammatory response by targeting the RhoA/Rho kinase and NF‐kB pathways

Benign prostatic hyperplasia (BPH) is characterized by an important inflammatory component. Stimulation of human prostate stromal cells from BPH tissues with proinflammatory cytokines leads to secretion of IL‐8, a chemokine involved in BPH pathogenesis. The vitamin D receptor (VDR) agonist elocalcitol can arrest prostate growth in BPH patients, but its mechanism of action in this pathology is still incompletely understood.
Position sense at the proximal interphalangeal joint is distorted in patients with rheumatoid arthritis of finger joints

The results of this investigation demonstrate, using a position matching paradigm, that the ability of subjects to detect changes in the position of the proximal interphalangeal joint is impaired in patients with rheumatoid arthritis affecting this joint. In this group there is a systematic flexion bias in position judgements compared to an age‐ and sex‐matched control group. This bias becomes progressively more pronounced at more extended positions. These results suggest that chronic inflammatory joint disease significantly alters proprioceptive sensations at finger joints and this may be due to the loss or distortion of afferent feedback from mechanoreceptors innervating the affected joint.
Delusional beliefs in psychotic depression vary according to age of onset

It has been suggested that the onset of psychotic disorders in later life plays a crucial role in the type of delusional beliefs (DBs). This hypothesis originates from clinical studies conducted in patients suffering mainly from schizophrenic and delusional disorders. In this context, it has been indicated that hypochon-driacal DBs peak between 20–30 years as well as over 60 years, whereas the theme of persecution peaks between 20–50 years (Musalek et al ., 1989). However, to the best of our knowledge, no studies have directly compared the types of DBs in major psychotic depression (PMD) between different age groups. Thus, the aim of this study was to investigate whether the DBs in PMD vary according to patient’s age at onset. Our sample comprised 55 (15 male and 40 female) patients consecutively admitted to the First Department of Psyciatry, Eginition Hospital (40) and to the Psychogeriatric Department of ‘Dromocaition’ Hospital (15), suffering from their ﬁrst depressive episode with psychotic features according to DSM IV (APA, 2000) criteria. All patients were assessed by means of SCID-I/P for DSM IV as well as Mini Mental State Examination