Miracle-dz/UniFAR-FTUs huggingface dataset:
AN EMPIRICAL EVALUATION OF STUDENT ACCOMMODATION QUALITY IN HIGHER EDUCATION

his paper, which was part of a larger study, aimed at examining student accommodation quality (SAQ) in two public tertiary institutions in Ghana. The study was a cross-sectional survey that involved a convenient sample of 700 tertiary students from College of Technology Education, Kumasi (COLTEK) of the University of Education, Winneba, and Kumasi Polytechnic (K-Poly). A selfadministered structured questionnaire was administered to the respondents in a survey that resulted in a 66.6% response rate for analysis. The findings indicate that SAQ items that received unfavourable rating include: bath room, access to transport, toilet, security, kitchen, entertainment, reading room, accommodation fees and searching cost. Moreover, it was found that students at COLTEK seem to be better in terms of SAQ in core facility, while those at K-Poly seem to be better in terms of accommodation cost, and some facilitating and support facilities. The results show that residential SAQ seems to be better than non-residential in terms of the distance to lecture and entertainment, while non-residential SAQ appears to better n areas such as overall quality, enjoying accommodation and core facilities. Recommendations and implications for management of higher education and student accommodation developers have been discussed. The paper contributes to the literature in the area of management of student accommodation and housing in tertiary education.
Consumer values, fashion consciousness and behavioural intentions in the online fashion retail sector

PurposeThe purpose of this paper is to study the underlying relationships among two distinct forms of consumer values, namely, instrumental and terminal values, fashion consciousness and behavioural intentions in the context of online fashion apparel retail sector.Design/methodology/approachA conceptual model and subsequent measurement scale were developed, grounded on in-depth review of the extensive literature and validated with customers engaged in online shopping of fashion apparels. The model was empirically examined, and a total of 395 responses were gathered from an online survey administered at a northeastern university in India. The model was validated using structural equation modelling, and a two-step approach suggested by Anderson and Gerbing (1988) was used to evaluate the measurement and structural models for the research.FindingsThe results of the study indicate that instrumental and terminal values significantly affect fashion consciousness, and fashion consciousness has a significant impact on behavioural intentions as well. The research brings out that fashion consciousness acts as a partial mediator between instrumental/terminal values and behavioural intentions. It is noteworthy that compared to terminal values instrumental values display a greater influence on both the variables fashion consciousness and behavioural intentions.Research limitations/implicationsThe conclusion of present research will notably assist the fashion retailers, online marketing researchers and experts understand the importance of terminal and instrumental values in increasing fashion consciousness, leading to strategically design campaigns for promoting and instigate consumers’ positive behavioural intentions in the best interest of the online fashion retail sector.Practical implicationsThe study results provide suggestions for competitive marketing strategies for online fashion companies operating in the emerging markets like India.Originality/valueThe present study is first of its kind attempt to use Rokeach’s (1973) two-dimensional measure of human values, in order to discover the terminal and instrumental values relationship and their influence on fashion consciousness and behavioural intentions in the online fashion retail industry.
Effects of estrogen on growth plate senescence and epiphyseal fusion

Estrogen is critical for epiphyseal fusion in both young men and women. In this study, we explored the cellular mechanisms by which estrogen causes this phenomenon. Juvenile ovariectomized female rabbits received either 70 μg/kg estradiol cypionate or vehicle i.m. once a week. Growth plates from the proximal tibia, distal tibia, and distal femur were analyzed after 2, 4, 6, or 8 weeks of treatment. In vehicle-treated animals, there was a gradual senescent decline in tibial growth rate, rate of chondrocyte proliferation, growth plate height, number of proliferative chondrocytes, number of hypertrophic chondrocytes, size of terminal hypertrophic chondrocytes, and column density. Estrogen treatment accelerated the senescent decline in all of these parameters. In senescent growth plates, epiphyseal fusion was observed to be an abrupt event in which all remaining chondrocytes were rapidly replaced by bone elements. Fusion occurred when the rate of chondrocyte proliferation approached zero. Estrogen caused this proliferative exhaustion and fusion to occur earlier. Our data suggest that (i) epiphyseal fusion is triggered when the proliferative potential of growth plate chondrocytes is exhausted; and (ii) estrogen does not induce growth plate ossification directly; instead, estrogen accelerates the programmed senescence of the growth plate, thus causing earlier proliferative exhaustion and consequently earlier fusion.
Historical origins of current IBD concepts.

INTRODUCTION The“nonspecific” inflammatory bowel diseases ,ulcerative colitis and Crohn,s represent a group of heterogeneous inflammatory and ulcerative disases of the small and large intestines of unknown etiology ,associated with many gastrointestinal and systemic complications . Appearing initially as isolated cases in Great Britain and northern Europe during the 19th and early 20th centuries ,they have steadily increased numerically and geographically and today are recognized worldwide.
Deregulated E2F Activity Induces Hyperplasia and Senescence-Like Features in the Mouse Pituitary Gland

ABSTRACT The retinoblastoma gene, RB1, is one of the most frequently mutated genes in human cancer. Rb heterozygous mice develop pituitary tumors with 100% incidence, and the E2F transcription factors are required for this. To assess whether deregulated E2F activity is sufficient to induce pituitary tumors, we generated transgenic mice expressing an inducible E2F3 protein in the intermediate lobe of the pituitary gland. We found that short-term deregulation of E2F activity, similar to the earliest stages of Rb loss, is able to induce abnormal proliferation of otherwise quiescent melanotrophs. However, while long-term exposure to deregulated E2F activity results in hyperplasia of the intermediate lobe, it did not lead to tumor formation. In fact, melanotrophs become insensitive to sustained E2F stimulation and enter an irreversible senescence-like state. Thus, although deregulated E2F activity results in hyperproliferation, it is not sufficient to mimic loss of Rb, sustain proliferation of melanotrophs, and ultimately induce pituitary tumors. Similarly, we found that primary cells in tissue culture become insensitive to sustained E2F3 activation and undergo premature senescence in a pRB-, p16Ink4a-, and p19Arf-dependent manner. Thus, we conclude that deregulated E2F activity is not sufficient to fully mimic loss of Rb due to the engagement of a senescence response.
Recruiting via social networking sites : the influence of scarcity and information specificity within recruitment via social networking sites on one's attractiveness toward the job advertisement and level of engagement.

Nowadays it is hard for recruitment organizations to differentiate themselves from others, considering the rise of the internet. However, there are some factors such as scarcity and information specificity than can play an important role in the process of recruiting via social networking sites. Attractiveness and engagement turn out to be important psychological concepts within employer branding. Therefore, this study aims to investigate whether the use of scarcity and information specificity in job advertisements offered via social networking sites positively affects potential job seekers’ attractiveness toward the job advertisement and level of engagement, and if their familiarity with the company moderates this. The current research employed this combination in a 2 (no scarcity vs. scarcity) x 2 (general information vs. specified information) x 2 (unknown vs. well-known company) between subjects design. Findings showed that respondents were more attracted toward the advertisement and they were more engaged if it includes specific information compared to general information. Respondents were also more attracted and more engaged toward a well-known company compared to an unknown company. However, it is especially important for unknown companies to use information specificity which leads to more attractiveness toward the job and to a higher level of engagement.
Accumulation of slowly activating delayed rectifier potassium current (IKs) in canine ventricular myocytes

In guinea‐pig ventricular myocytes, in which the deactivation of slowly activating delayed rectifier potassium current (IKs) is slow, IKs can be increased by rapid pacing as a result of incomplete deactivation and subsequent current accumulation. Whether accumulation of IKs occurs in dogs, in which the deactivation is much faster, is still unclear. In this study the conditions under which accumulation occurs in canine ventricular myocytes were studied with regard to its physiological relevance in controlling action potential duration (APD). At baseline, square pulse voltage clamp experiments revealed that the accumulation of canine IKs could occur, but only at rather short interpulse intervals (< 100 ms). With action potential (AP) clamp commands of constant duration (originally recorded at rate of 2 Hz), an accumulation was only found at interpulse intervals close to 0 ms. Transmembrane potential recordings with high‐resistance microelectrodes revealed, however, that at the fastest stimulation rates with normally captured APs (5 Hz) the interpulse interval exceeded 50 ms. This suggested that no IKs accumulation occurs, which was supported by the lack of effect of an IKs blocker, HMR 1556 (500 nM), on APD. In the presence of the β‐adrenergic receptor agonist isoproterenol (isoprenaline, 100 nM) the accumulation with AP clamp commands of constant duration was much more pronounced and a significant accumulating current was found at a relevant interpulse interval of 100 ms. HMR 1556 prolonged APD, but this lengthening was reverse rate dependent. AP clamp experiments in a physiologically relevant setting (short, high rate APs delivered at a corresponding rate) revealed a limited accumulation of IKs in the presence of isoproterenol. In conclusion, a physiologically relevant accumulation of IKs was only observed in the presence of isoproterenol. Block of IKs, however, led to a reverse rate‐dependent prolongation of APD indicating that IKs does not have a dominant role at short cycle lengths.
Effect of Entrepreneur Psychological Capital and Human Resources on the Performance of the Catering Industry in Indonesia

This study aims to determine and analyze the influence of Entrepreneur's Psychological Capital and Human Resources on the performance of the catering industry in Indonesia. The research method is used in an experimental survey with hypothesis testing. Data was collected for business catering actors in Bandung, West Java, Indonesia. The data that has been collected is analyzed by using Multiple Regression. Based on the results of research, It is known that Psychological Entrepreneur capital variables of entrepreneurs have the most influence on the performance of UKM catering compared to other variables studied with a coefficient of 0.465. Then other variables that have an influence on the performance of SME catering are human resource management variables with a coefficient of 0.393. This finding implies that in order to improve the performance of Catering SMEs, it is necessary to improve psychological entrepreneur capital and human resource management.
Influence of shareholders’ support over mergers and acquisitions in US banks

Abstract Using data about the US banking industry, the study investigates how the support disclosed by funds in corporate meetings influences the success of the completion of mergers and acquisitions (M&A). The methodological approach relies on the use of instrumental variables with the generalised method of moments (GMM). The results indicate that the voting support exercises a negative influence over the success of M&A, validating the probable presence of agency-driven behaviour in explaining M&A completion, and indicating that low governance and activism inspires independent behaviour of managers, proceeding against the wishes, position or interests of shareholders. Considering that voting performance has been reported as a proxy for reputational harm, the results provide some understanding about how the success in M&A in the US banking industry may be related to reputational consequences infiltrated through voting decisions.
Application and Implementation of E-Procurement Technologies in Malaysian Manufacturing Firm

In the present scenario of global business competition, web-based technology is of great importance. It has become an extremely important criterion where businesses are now adopting e-commerce such as electronic procurement for the operation management of their organization. Despite this, they are still experiencing slow adoption of e-procurement. The main objective of this study was to determine the extent of e-procurement implementation in Malaysia organization as well as identify the relationship between the e-procurement system and supply chain performance among organizations in Malaysia. The study anchored on relevant theories on e-procurement which was Technology Acceptance Model. This study used descriptive research design. The population of this study was the employees from the manufacturing firms in Malaysia. A questionnaire was used to collect data. Data collected was analyzed quantitatively through the Statistical Package for the Social Sciences (SPSS). The procurement processes include E-ordering, E-sourcing, E-tendering, E-reverse auctioning and E-informing. The findings indicated that the firms had implemented E-procurement to a moderate extent. The respondents indicated that E-tendering was highly implemented in the organization in order to improve the supply chain performance to a large percentage (M=3.92, SD=0.701). The results also identified that the e-procurement system was positively associated with the supply chain performance of the organization. This study provides insights into manufacturing firms regarding the importance of E-procurement technologies.
Postural variations of nasal patency.

Comparative quantitative measurements of the nasal airway resistance (Rn) in different positions were performed in normal individuals, in patients with allergic rhinitis, and in patients with common colds during and after infection. In normal persons and in patients recovered from common colds Rn increased only very little in positions of 20° or less above the horizontal plane. In rhinitic patients the same positions were followed by a considerable increase of Rn caused by swelling of the. nasal mucosa due to hydrostatic blood pressure increase. This was proved by the effect of neck vein compression causing about the same increase of Rn as the horizontal position. The mucosal reactions to high transmural pressures support the theory of vascular hypotonicity in the rhinitic nose. In view of the biological and clinical consequences of the postural effects on the nasal mucosa, common colds should not be “cured” with bed rest; at night, rhinitic patients should take up a body position of more than 204dG above.
Oral cancer prediction using gene expression profiling and machine learning

Oral premalignant lesion (OPL) patients have a high risk of developing oral cancer. In this study we investigate using machine learning techniques with gene expression profiling to predict the possibility of oral cancer development in OPL patients. Four classification techniques were used: support vector machine (SVM), Regularized Least Squares (RLS), multi-layer perceptron (MLP) with back propagation and deep neural network (DNN). Fisher discriminate analysis was used to select relevant features from the gene expression array. The results show high accuracy (96%) using DNN and 94% accuracy using SVM and MLP with one sample cross validation. Furthermore, we achieved the same results using 10-fold cross validation.
The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5*

Background: Kinesin-5 motors are important for formation and maintenance of the bipolar mitotic spindle. Results: ATP binding triggers coupled conformational changes of kinesin-5 specific structural elements in the microtubule-bound motor domain. Conclusion: Kinesin-5 mechanochemistry is tuned to its cellular functions. Significance: Subnanometer resolution structure determination of microtubule-bound kinesin-5s and kinetics experiments reveal the molecular basis of their motor properties and of drug inhibition. Kinesin-5 is required for forming the bipolar spindle during mitosis. Its motor domain, which contains nucleotide and microtubule binding sites and mechanical elements to generate force, has evolved distinct properties for its spindle-based functions. In this study, we report subnanometer resolution cryoelectron microscopy reconstructions of microtubule-bound human kinesin-5 before and after nucleotide binding and combine this information with studies of the kinetics of nucleotide-induced neck linker and cover strand movement. These studies reveal coupled, nucleotide-dependent conformational changes that explain many of this motor's properties. We find that ATP binding induces a ratchet-like docking of the neck linker and simultaneous, parallel docking of the N-terminal cover strand. Loop L5, the binding site for allosteric inhibitors of kinesin-5, also undergoes a dramatic reorientation when ATP binds, suggesting that it is directly involved in controlling nucleotide binding. Our structures indicate that allosteric inhibitors of human kinesin-5, which are being developed as anti-cancer therapeutics, bind to a motor conformation that occurs in the course of normal function. However, due to evolutionarily defined sequence variations in L5, this conformation is not adopted by invertebrate kinesin-5s, explaining their resistance to drug inhibition. Together, our data reveal the precision with which the molecular mechanism of kinesin-5 motors has evolved for force generation.
The B&B sector in Nova Scotia: Some preliminary evidence from Tripadvisor reviews

The following paper examines small accommodations firms, specifically 190 B&B operations in Nova Scotia, Canada in terms of recent online reviews on Tripadvisor. In particular the paper initially provides an overview of the bed-and-breakfast (B&B) sector in terms of select characteristics. It then examines Tripadvisor reviewers’ ratings in terms of Tripadvisor’s six sub elements, overall star ratings provided by Tripadvisor itself, and B&B participation in a provincial-government tourism program and a national star-rating system for accommodations. The extent to which B&B owners/managers respond differentially to poor and terrible reviews relative to very good and excellent reviews is also considered. Relationships between B&B prices and Tripadvisor reviewer overall ratings, Tripadvisor star ratings, the reviewers’ rating of the six attributes, and tendency of owners/managers to respond to Tripadvisor are also examined. Lastly, implications of the findings for the B&B sector are discussed along with limitations to this study and directions for future research.
Regulation of the heat‐shock response by interferon in mouse L cells

Interferon (IFN) is not able to induce heat‐shock protein (HSP) synthesis. However IFN pretreatment of mouse L cells has been shown to enhance the decrease of overall protein synthesis which follows a heat shock, and to stimulate the accumulation of HSPs. We show here that the synthesis of a protein (the hepatitis B virus surface antigen) under the control of a Drosophila HSP 70 promoter is also stimulated in IFN‐pretreated cells. The regulation by IFN takes place at two levels: first, the rate of HSP gene transcription is increased in nuclei isolated from IFN‐treated cells; second, the synthesis of HSPs is prolonged after pretreatment with IFN. Experiments performed in the presence of actinomycin D show that this effect is due to a stablization by IFN of mRNAs coding for HSPs.
Surface potential decay of epoxy/Al2O3 nanocomposites irradiated with high energy electron beam

Surface potential decay on electron beam irradiated epoxy based nanocomposites has been investigated in this paper. The 2 mm-thick laminate composites sample was irradiated with the electron beam at an average energy of 7.5 MeV, and the total accumulated dose was up to 500 kGy. After the irradiation, the nanocomposites were corona charged with DC voltage at 10 kV through a pair of needle to plate electrode. Surface potential of the sample was then measured by means of an electrostatic voltmeter and the trap distribution, carrier mobility could be estimated. Results obtained indicated that the presence of nano-filler in the nanocomposites played an important role in varying the charge transportation behavior both before and after the irradiation. It is proposed that the radiation induced variation in chemical and physical structures of the nanocomposites is responsible for the accumulated dose dependent charge transportation manner.
Osteochondral Lesions of the Capitellum in Pediatric Patients: Role of Magnetic Resonance Imaging

The role of magnetic resonance imaging (MRI) in the evaluation of patients with osteochondral lesions of the capitellum is undefined. To define its role, the cases of nine consecutive children with 11 capitellar osteochondral lesions who underwent MRI were reviewed. Magnetic resonance imaging accurately delineated the size of the osteochondral lesions and identified capitellar loose bodies not seen on plain radiographs in two elbows. In patients without capitellar loose bodies, two distinct MRI patterns existed that were similar to those seen in femoral head osteonecrosis. Magnetic resonance imaging aided in the treatment of children with osteochondral lesions of the capitellum. Further studies are necessary to define the significance of the two MRI patterns.
Neoplasms of the scapula.

1729 he scapula is a small bone in which many neoplasms can develop. Few radiology articles report the types and appearances of these tumors. The Musculoskeletal Tumor Society has developed a classification system for shoulder girdle tumors that divides the scapula into two zones [1]: the acromial–glenoid complex comprises the S2 region and the blade–spine portion comprises the S1 region (Fig. 1). The system helps provide a functional classification for resections and reconstructions and a logical division of the abnormalties that develop in the scapula. Neoplasms of the S1 region include those that commonly develop in the flat bones (i.e., Ewing’s sarcoma, multiple myeloma, and lymphoma). Neoplasms of the S2 region include those that commonly develop at the ends of the bone (i.e., giant cell tumors and aneurysmal bone cysts) [2]. We describe bone neoplasms that develop in the scapula and present examples of these tumors on radiographs, CT scans, and MR images.