Miracle-dz/UniFAR-FTUs huggingface dataset:
Amoebic gill disease outbreak in marine fish cultured in Korea

In 2015, 6.7–60% mortality was observed in black seabream (Acanthopagrus schlegelii), rock bream (Oplegnathus fasciatus), and gray mullet (Mugil cephalus) farmed in the southern coast of Korea. On examination, numerous amoebae were found on the gills of these 3 fish species with detection rate of 100%. Some rock bream and gray mullet were coinfected with bacteria (Pseudomonas anguilliseptica, Vibrio tapetis, or Vibrio anguillarum). Histologic examination revealed extensive hyperplastic epithelium and lamellar fusion in the gills. Numerous amoebae were seen between gill filaments. The amoebae collected from the 3 fish species had specific 630 bp of a partial 18S rRNA gene fragment for Neoparamoeba perurans. Phylogenetic analysis based on partial 18S rRNA gene nucleotide sequences revealed that these Korean amoeba isolates belonged to the N. perurans group. Based on our results, black seabream, rock bream, and gray mullet were added as new hosts for N. perurans.
Serving Children with Serious Emotional Disturbance in a System of Care

Children in need of mental health services do not constitute a homogeneous group. Important to this discussion is an examination of the diverse presenting problems and psychosocial histories of children referred by different service agencies. Using data from the East Baltimore Mental Health Partnership (EBMHP), we determined whether and how children referred to the EBMHP from a traditional mental health center differed from children referred to the EBMHP by non—mental health agencies. Data on demography, family background, and child and family functioning were collected on 254 children and their families. The analyses confirmed that children with serious emotional disturbance served in a system of care and their families are not homogeneous. Children and their families differed in terms of their sociodemographic characteristics and psychosocial adjustment depending on their referral source. These differences are discussed in terms of service planning and delivery, as well as theoretical implications.
Adherence compounds in embryo transfer media for assisted reproductive technologies.

BACKGROUND In order to increase the success rate of assisted reproductive technologies (ART), adherence compounds such as hyaluronic acid and fibrin sealant have been introduced into subfertility management. Adherence compounds are added to the embryo transfer medium in order to increase the likelihood of embryo implantation, with the potential for higher clinical pregnancy and live birth rates. OBJECTIVES To determine whether embryo transfer media containing adherence compounds affect the live birth rate in ART compared to transfer media without adherence compounds. SEARCH STRATEGY The Menstrual Disorders and Subfertility Group Trials Register, Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE and PsycINFO electronic databases were searched (to 26th May 2009) for publications which described randomised controlled trials of the addition of adherence compounds to embryo transfer media. Furthermore, reference lists of all obtained studies were checked and conference abstracts handsearched. SELECTION CRITERIA Only truly randomised controlled trials comparing embryo transfer media containing adherence compounds with transfer media without (or with lower doses of) adherence compounds were included. The adherence compounds that were evaluated were hyaluronic acid and fibrin sealant. DATA COLLECTION AND ANALYSIS One review author selected the trials for inclusion according to the above criteria, after which two authors independently extracted the data for subsequent analysis. The statistical analysis was performed in accordance with the guidelines developed by The Cochrane Collaboration. MAIN RESULTS Sixteen studies with a total of 3698 participants were analysed. One studied fibrin sealant, the other 15 studied hyaluronic acid. There was no evidence of a treatment effect of fibrin sealant as an adherence compound. For hyaluronic acid, there was no evidence of a treatment effect on live birth rate. Evidence of treatment effects could be found for the clinical pregnancy rate (OR 1.41, 95% CI 1.22 to 1.63; P < 0.00001) and the multiple pregnancy rate (OR 1.86, 95% CI 1.49 to 2.31; P < 0.00001), with higher rates in the hyaluronic acid groups. No evidence of treatment effect was found for the other outcomes. AUTHORS' CONCLUSIONS There is evidence of an improved clinical pregnancy rate with the use of adherence compounds in ART cycles but no evidence of an effect on live birth rate. The increase in multiple pregnancy rate may be the result of the use of a combination of an adherence compound and a policy of transferring more than one embryo. Further studies of adherence compounds with single embryo transfer need to be undertaken.
Detection of Treponema phagedenis–like antibodies in serum and bulk milk from cows with and without digital dermatitis

Digital dermatitis (DD) in dairy cows is a widespread disease linked to infection with Treponema. The traditional diagnostic method is clinical inspection, which is subjective and laborious. We explored the performance of 4 different immunogenic proteins from Treponema phagedenis in a new antibody ELISA for analysis of serum or milk. Analysis of samples from 390 cows in 25 herds showed that the ELISA could distinguish the majority of cows with DD from healthy cows. By changing the cutoff and applying parallel or serial testing, high sensitivity or specificity could be achieved. The investigation indicated that aggregated test results can be useful in the assessment of a herd’s DD status. In addition, analysis of bulk tank milk samples showed good agreement with results from individual cows. The test system could be useful in research on the epidemiology and immunology of DD.
Health-Related Quality of Life Relates to School Attendance in Children on Treatment for Cancer

The aims of this study are to follow health-related quality of life (HRQOL), school attendance, and social interaction with friends in children with cancer and to explore potential relationships between HRQOL and school attendance. The study also describes self-reported reasons for not attending school and not meeting friends. During a 2-year period, all schoolchildren in Sweden starting treatment for cancer were invited to participate in the study. Participants (N = 101) were assessed 3 times during the first 5 months of treatment using 2 questionnaires: DISABKIDS Chronic Generic Module (DCGM-37) and a study-specific questionnaire. The results indicate a diminished HRQOL that remained stable over the study period, with girls rating worse HRQOL compared with boys. School attendance significantly increased over time, and approximately half of the children attended school 5 months after start of treatment. Self-reported HRQOL was positively correlated to days of school attendance. The results emphasize the importance of psychosocial care and nursing for children diagnosed with cancer, especially for girls. Research to further explore gender differences in HRQOL among children diagnosed for cancer is recommended.
Chemotherapy-Related Side Effects in Childhood Acute Lymphoblastic Leukemia in Indonesia: Parental Perceptions

Noncompliance with prescribed medication has been associated with increased chance of relapse and poor outcome. Side effects may be an important cause of noncompliance. Fifty-one parents of children with acute lymphoblastic leukemia in a tertiary care hospital in Indonesia were interviewed about their perception of side effects and their impact on treatment noncompliance and daily activities. A symptom checklist assessing 13 common symptoms was used to examine side effects. During chemotherapy, childhood acute lymphoblastic leukemia patients suffered from psychological as well as physical side effects. The most frequent side effect reported by parents was behavior alteration (92%). Second and third in frequency were increased appetite and infections, reported by 88% and 83% of parents, respectively. The most severe side effects were leg weakness, increased appetite, and behavior alteration. The overall frequency of side effects was weakly correlated to noncompliance. Reducing the impact of side effects may increase compliance with the treatment.
Gut microbes shape response to cancer immunotherapy.

This week, two studies offer a raft of evidence from cancer patients suggesting that the gut microbiome—the community of bacteria, viruses, and other bugs living in our digestive tracts—helps determine whether tumors shrink when treated with a powerful new type of cancer drug. Patients who took antibiotics for routine reasons before or soon after starting a type of immunotherapy known as a PD-1 inhibitor relapsed and died sooner than those who were antibiotic-free. And when mice received fecal transplants from patients who responded to the drugs, they did better on PD-1 blockers than did mice given nonresponder feces. Researchers are now planning a clinical trial to test whether manipulating the gut microbiome could help more cancer patients respond to PD-1 blockers.
Pneumocystis carinii Pneumonia Prophylaxis

Pneumocystis pneumonia (PCP) can be life threatening for children receiving chemotherapy and immunosuppressive medication, including high-dose steroids. Although there are no current guidelines for prophylaxis in pediatric oncology patients, ongoing studies are evaluating the efficacy, side effects, ease of administration, and compliance of drugs used for PCP prophylaxis. Drugs currently being prescribed in practice include Bactrim, pentamidine, dapsone, and atovaquone. Bactrim remains superior for preventing PCP, but alternatives are being analyzed and investigated for those unable to tolerate Bactrim because of drug allergy or side effects. Educating patients and families about the importance of PCP prophylaxis and compliance should be a priority for all health care providers caring for children receiving immunosuppressive medications, including chemotherapy.
Results of a Nurse-Led Intervention

The objectives of this study were to assess the feasibility and perceived academic/psychosocial outcomes of a pilot program using videoconferencing facilities to connect children with cancer to their home school. Eight parents, three patients, and five teachers (n = 16) participated in semistructured interviews evaluating the efficacy/feasibility of this program. Results were analyzed using the qualitative framework of Miles and Huberman. Parents reported that videoconferencing provided the family with a sense of normalcy and connection to the outside world (4/8), often boosting patients’ mood (6/8). Further benefits included stronger relationships with classmates and teachers (15/16) and improved peer acceptance and school reintegration. There were no notable impacts on patients’ academic progression. Reported barriers included: costs, time commitments, bureaucratic hurdles, and technical and logistical difficulties. Videoconferencing technologies provide an important tool to connect childhood cancer patients to their classrooms; however, further solution-based investigation is warranted to overcome existing barriers.
Rasch Analysis of the Arabic Language Version of the Functional Disability Inventory

It is important for the responsive and effective treatment of pediatric cancer patients that functional disability is successfully measured, but no measures of functional disability have been validated for use with Arabic-speaking children and adolescents. The purpose of this study was to examine the psychometric characteristics of the first Arabic translation of the Functional Disability Inventory (FDI). A methodological study limited to the secondary analysis of functional disability data on 62 pediatric patients in Lebanon using the rating scale model and WINSTEPS Rasch analysis software was used. Disordered responses to 4 FDI times suggest that the Arabic translation of the rating scale categories might need revision or supplementation with a visual analogue scale. The dimensionality of the FDI needs further exploration because principal component analyses of residuals suggested the presence of secondary and possibly higher order dimensions. Additional FDI items are needed to improve targeting if low levels of functional disability are demonstrated to be clinically important for patient assessment and pain management. The FDI-A is suitable for clinical assessment and for monitoring the outcomes of pain management in Lebanese pediatric cancer patients. Our findings support the construct validity of the FDI-A and acceptable reliability for the 15-item scale, Cronbach α . 93 and . 85 for 4 of the item subsets we examined. Rating scale categories and the dimensionality of the FDI-A require further examination. The clinical relevance of distinctions between levels of functional disability in children and adolescents with cancer pain remains to be established.
Design of an Error-Tolerance Scheme for Discrete Wavelet Transform in JPEG 2000 Encoder

The JPEG 2000 image compression standard is designed for a broad range of data compression applications. The discrete wavelet transformation (DWT), central to the signal analysis and important in the JPEG 2000, is quite susceptible to computer-induced errors. The errors can be spread to many output transform coefficients if the DWT is implemented by using lifting scheme. This paper proposes an efficient error tolerance scheme (ETS) to detect errors occurring in DWT. A pipeline-based DWT structure is also developed in this paper to speed up the error detection process. The proposed ETS design uses weighting sums of the DWT coefficients at the output compared with an equivalent check value derived from the input-data. With the proposed ETS design, the errors introduced at DWT can be effectively detected. Additionally, the results of error detection can be further analyzed and evaluated to show the capability of error tolerance. Some standard images are used as test samples to verify the feasibility of the proposed ETS design. Experimental results and comparisons show that the proposed ETS has good performance in error detection time and error tolerance capability.
QCA Systolic Array Design

Quantum-dot Cellular Automata (QCA) technology is a promising potential alternative to CMOS technology. To explore the characteristics of QCA and suitable design methodologies, digital circuit design approaches have been investigated. Due to the inherent wire delay in QCA, pipelined architectures appear to be a particularly suitable design technique. Also, because of the pipeline nature of QCA technology, it is not suitable for a complicated control system design. Systolic arrays take advantage of pipelining, parallelism, and simple local control. Therefore, an investigation into these architectures in semiconductor QCA technology is provided in this paper. Two case studies, (a matrix multiplier and a Galois Field multiplier) are designed and analyzed based on both multilayer and coplanar crossings. The performance of these two types of interconnections are compared and it is found that even though coplanar crossings are currently more practical, they tend to occupy a larger design area and incur slightly more delay. A general semiconductor QCA systolic array design methodology is also proposed. It is found that by applying a systolic array structure in QCA design, significant benefits can be achieved particularly with large systolic arrays, even more so than when applied in CMOS-based technology.
Infertility Education

The majority of children diagnosed with cancer will become long-term survivors; however, many will suffer late effects of treatment, including infertility. Educating patients about potential risk for infertility is important, yet little is known regarding when patients would like to hear this information. The purpose of this study was to assess young adult survivors’ previous experience in receiving education about their risk for infertility and determine their preferences for infertility education at various time points during and after treatment. Only 36% of survivors report receiving education about risk for infertility at diagnosis, 39% at end of therapy, and 72% in long-term follow-up/survivor clinic visits. Survivors consistently identified their oncologist as a preferred educator at each time point. Although almost all participants identified wanting education at diagnosis, this time point alone may not be sufficient. End of therapy and survivorship may be times this message should be repeated and adapted for the survivor’s needs and developmental stage: conversations about the impact of cancer treatment on future fertility should be ongoing.
Overview of the SpiNNaker System Architecture

SpiNNaker (a contraction of Spiking Neural Network Architecture) is a million-core computing engine whose flagship goal is to be able to simulate the behavior of aggregates of up to a billion neurons in real time. It consists of an array of ARM9 cores, communicating via packets carried by a custom interconnect fabric. The packets are small (40 or 72 bits), and their transmission is brokered entirely by hardware, giving the overall engine an extremely high bisection bandwidth of over 5 billion packets/s. Three of the principal axioms of parallel machine design (memory coherence, synchronicity, and determinism) have been discarded in the design without, surprisingly, compromising the ability to perform meaningful computations. A further attribute of the system is the acknowledgment, from the initial design stages, that the sheer size of the implementation will make component failures an inevitable aspect of day-to-day operation, and fault detection and recovery mechanisms have been built into the system at many levels of abstraction. This paper describes the architecture of the machine and outlines the underlying design philosophy; software and applications are to be described in detail elsewhere, and only introduced in passing here as necessary to illuminate the description.
Factors Influencing Posttraumatic Growth in Mothers of Children With Cancer

The psychological adaptation of mothers of children with cancer has a significant impact on the management of the disease. As the mothers’ psychological adaptation and positive emotions have an impact on the psychological adaptation of the children, it is important to facilitate the positive growth of the mothers during their adjustment to their children’s illness. Therefore, it is necessary to determine the factors that influence posttraumatic growth (PTG) in these mothers. This research aimed to test the variables of PTG based on an existing theoretical model of PTG in mothers of children with cancer. Data were collected, using self-report questionnaires, from 222 mothers of children with cancer who visited an outpatient clinic between August 9 and September 17, 2013. The variables of optimism, disruption of core beliefs, social support, and deliberate rumination accounted for 41.4% of the variance in the mothers’ PTG. Social support and deliberate rumination are important factors directly affecting PTG in mothers of children with cancer.
Predicted normal values of pulmonary function tests in normal Korean children

Purpose: Pulmonary function tests are useful and important methods for evaluating patients with respiratory diseases. To assess lung function, we need to establish normal values of lung function, which vary according to population, age, gender and growth, particularly in children. This study was undertaken to establish normal predicted values of pulmonary function tests and to predict renewed reference values by spirometry in Korean school children. Methods: Spirometric forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), forced expiratory flow at 25% to 75% of FVC (FEF25%-75%), and peak expiratory flow rate (PEFR) were measured in 406 healthy elementary school children (age, 6-12 years old) in May, 2012. Multiple linear regression analysis was performed for each spirometric parameter against age, height, weight and body surface area (BSA) separately for boys and girls, and derived reference equations and coefficients for all the spirometric parameters. Results: All the measured spirometric parameters were significantly correlated with age, height, weight, and BSA. FVC was higher in boys aged 6-10 years than girls at ages matched. Height showed the highest correlation coefficient for all the spirometric parameters followed by BSA, weight and age in both genders. The normal predicted values of FVC and FEV1 at 130 cm in this study using renewed reference equations were approximately in the middle compared to previous studies. Conclusion: We reported here the renewed reference equations for normal predicted values of pulmonary function tests with high coefficients of determination based on updated data in healthy Korean children.
Speech perception with hearing aids: Effects of noise reduction and directional microphone systems on amplified signals

Our objective was to measure the variations of speech reception threshold (SRT) in noise induced by hearing aids with or without noise reduction (NR) and directional microphone systems (DM). Data were collected from 10 normal hearing volunteers wearing bilateral hearing aids and tested in a sound field of speech and noise. SRT was measured in function of: 1) speech source azimuth (0°,90°,180°); 2) background noise (monophonic vs. quadraphonic); 3) amplification (unaided vs. linearly aided); 4) amplification mode (linear, NR, DM, NR + DM). Compared using a hearing aid linear setting, NR does not improve the SRT in monophonic noise, while it improves the SRT by 2–3dB in quadraphonic noise with frontal and lateral speech. DM in monophonic noise improves frontal SRT (1dB) and worsens lateral and posterior SRT, while in quadraphonic noise frontal SRT is further advantaged and the DM negative effect disappears. With both devices activated a stronger positive effect is evident for frontal SRT in both noise fields (2–4dB) and for lateral SRT in quadraphonic noise. These results confirm that NR and DM can facilitate SRT in adverse noise conditions for normal hearing persons, and the results are useful as a reference for hearing impaired persons.
Health Disparities and Health-Seeking Behavior Among Latino Men

Many studies examining Latino health-seeking behavior have focused on comparing Latinos with other ethnic groups, primarily with Whites and African Americans. However, without the benefit of intragroup or intracultural comparisons, such studies fail to identify the subtle variation in health-seeking strategies and the range of needs within the Latino ethnic group, and thus are compromised in their capacity to guide and improve practice and policy. This article reviews the literature regarding health-seeking behavior and Latino men. Important factors identified include gender, occupation, and responsiveness of the health care system along with characteristics of the individual.
Evaluating Diversity in Nursing Education

This article presents the findings of a methodical examination of how well one school of nursing was meeting its goal of addressing diversity through its pedagogy. The underlying assumption was that a school's curriculum both shapes and reflects a climate of valuing diversity. This mixed-method evaluation study was conducted in four steps, including a content analysis of all syllabi in the School of Nursing's (SON) curriculum, comparison of the content analysis to students' evaluation of diversity in their education, a survey of the 2006 graduates, and an analysis of faculty responses to the findings. The findings are being used to guide the SON in the development of training and to bring about forums for formal dialogue. These will assist faculty to effectively integrate diversity in their teaching and interaction with students and to move toward the long-term goal of preparing culturally humble and sensitive clinicians, educators, and researchers.