Miracle-dz/UniFAR-FTUs huggingface dataset:
Angiotensin-converting enzyme inhibitory activity of polyphenolic compounds from Peperomia pellucida ( L ) Kunth : An in silico molecular docking study

Islamudin Ahmad1*, Azminah2,4, Kamarza Mulia3, Arry Yanuar4, Abdul Mun'im4* 1Department of Pharmaceutical Sciences, Faculty of Pharmacy, Mulawarman University, Samarinda, East Kalimantan, Indonesia. 2Faculty of Pharmacy, University of Surabaya, Surabaya, East Java, Indonesia. 3Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, Indonesia. 4Department of Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Indonesia, Depok, West Java, Indonesia.
A ff ect and control : A conceptual clari fi cation

Converging evidence seems to suggest that affect and cognitive control are related in interesting ways, and some researchers have suggested that affect may play a causal, or at least otherwise interesting role in cognitive control. Here I discuss reasons to believe that these claims are either unfounded or based on a conceptual misunderstanding. They are unfounded with respect to the role of conscious affective experience, which is not supported by any unequivocal evidence. And they are based on a conceptual misunderstanding with respect to unconscious affect: Given the strong conceptual overlap between affect on the one hand and cognitive control on the other, finding mechanisms that are shared by affect and control is an almost necessary outcome that does not provide any mechanistic insight but merely reflects the semantic overlap between the concepts. However, this overlap may be taken to expand our research perspective and take affect-related and control-related outcomes as equivalent markers of one underlying function that encompasses, and thus goes beyond the traditional concept of affect and control.
Spherical configurations over finite fields

abstract:We establish that if $d\geq 2k+6$ and $q$ is odd and sufficiently large with respect to $\alpha\in (0,1)$, then every set $A\subseteq{\bf F}_q^d$of size $|A|\geq\alpha q^d$ will contain an isometric copy of every spherical $(k+2)$-point configuration that spans $k$ dimensions.
FREQUENCY ANALYSIS OF CHAOTIC INTERMITTENCY MAPS WITH SLOWLY DECAYING CORRELATIONS

Established stochastic models for discrete-time long-memory processes are linear and Gaussian, and commonly require that the dth fractional-difference of the process has short memory 0 < d ≤ 0.5; if −0.5 < d < 0, the process is said to have an intermediate memory. Chaotic intermittency maps provide alternative nonlinear, non-Gaussian models for both classes of processes. An asymptotic expression for the rate at which the correlations of symmetric cusp map decay is developed, and the class of extended symmetric cusp maps is introduced. The small-frequency asymptotics of the polynomial, cusp and logarithmic maps are investigated, and it is shown that these maps can produce spectra with d = 0.5 on the one hand, d = 0 on the other, and yet the corresponding processes are stationary and have long-memory. Asymptotic expressions are derived for studying the bias of the small-frequency periodogram ordinates with these maps. Finite sample behaviour is examined in a simulation study.
A Novel Feature Engineering Framework in Digital Advertising Platform

Digital advertising is growing massively all over the world, and, nowadays, is the best way to reach potential customers, where they spend the vast majority of their time on the Internet. While an advertisement is an announcement online about something such as a product or service, predicting the probability that a user do any action on the ads, is critical to many web applications. Due to over billions daily active users, and millions daily active advertisers, a typical model should provide predictions on billions events per day. So, the main challenge lies in the large design space to address issues of scale, where we need to rely on a subset of well-designed features. In this paper, we propose a novel feature engineering framework, specialized in feature selection using the efficient statistical approaches, which significantly outperform the state-of-the-art ones. To justify our claim, a large dataset of a running marketing campaign is used to evaluate the efficiency of the proposed approaches, where the results illustrate their benefits.
Deep Neural Network Acoustic Models for ASR

Deep Neural Network acoustic models for ASR Abdel-rahman Mohamed Doctor of Philosophy Graduate Department of Computer Science University of Toronto 2014 Automatic speech recognition (ASR) is a key core technology for the information age. ASR systems have evolved from discriminating among isolated digits to recognizing telephone-quality, spontaneous speech, allowing for a growing number of practical applications in various sectors. Nevertheless, there are still serious challenges facing ASR which require major improvement in almost every stage of the speech recognition process. Until very recently, the standard approach to ASR had remained largely unchanged for many years. It used Hidden Markov Models (HMMs) to model the sequential structure of speech signals, with each HMM state using a mixture of diagonal covariance Gaussians (GMM) to model a spectral representation of the sound wave. This thesis describes new acoustic models based on Deep Neural Networks (DNN) that have begun to replace GMMs. For ASR, the deep structure of a DNN as well as its distributed representations allow for better generalization of learned features to new situations, even when only small amounts of training data are available. In addition, DNN acoustic models scale well to large vocabulary tasks significantly improving upon the best previous systems. Different input feature representations are analyzed to determine which one is more suitable for DNN acoustic models. Mel-frequency cepstral coefficients (MFCC) are inferior to log Mel-frequency spectral coefficients (MFSC) which help DNN models marginalize out speaker-specific information while focusing on discriminant phonetic features.
Regularizing the Factor Zoo with OWL : A Correlation-Robust Machine Learning Approach ∗

This paper sheds light on a new perspective of the “factor zoo enigma”, in which factor correlation prevails and worsens the “curse of dimensionality”. I introduce a newly developed machine learning tool, OWL, which circumvents complications from correlations in high dimensionality: it can identify and group correlated factors while shrinking off useless/redundant ones. I show that OWL estimator is consistent and I derive the grouping condition for correlated factors. Monte Carlo experiments show that OWL outperforms LASSO, adaptive LASSO and Elastic Net (EN) in various settings, particularly when factors are highly correlated. Empirical evidence suggests that liquidity related factors are primary to drive asset prices but cautions about a time-varying nature in factor selections. Out-of-sample analysis confirms superior performance of OWL hedged portfolios compared with LASSO, EN and Fama-MacBeth regression. JEL classification: C33 C52 C58 G12
Foundations to Query Labeled Property Graphs using SPARQL

The RDF (cid:63) /SPARQL (cid:63) approach extends RDF and SPARQL with means to capture and to query annotations of RDF triples, which is a feature that is natively available in graph databases modeled as Labeled Property Graphs (LPGs). Hence, the approach presents a step towards making the diﬀerent graph database models interoperable. This paper takes this step further by providing a solid theoretical foundation for converting LPGs into RDF (cid:63) data and for querying LPGs using the query language SPARQL (cid:63) . Regarding the latter, the contributions in this paper consider approaches that materialize the RDF (cid:63) representation of the LPGs into an RDF (cid:63) -enabled triplestore as well as approaches in which the queried LPGs may reside in an LPG-speciﬁc database system.
Expression of EIF 3p 48 / INT 6 , TID 1 and Patched in cancer , a profiling of multiple tumor types and correlation of expression June

June L. Traicoff* , Joon-Yong Chung, Till Braunschweig, Ilya Mazo, Youmin Shu, Arun Ramesh, Mark W. D’Amico, Mikhail M. Galperin, Vladimir Knezevic & Stephen M. Hewitt 20/20 GeneSystems, Inc., Rockville, MD, 20850, USA; Tissue Array Research Program, Laboratory of Pathology, National Cancer Institute, Bethesda, MD, 20892-4605, USA; Ariadne Genomics, Inc., Rockville, MD, 20850, USA; GeneHarbor, Inc., Rockville, MD, 20850, USA; PharmacoGenomics Research Center and Molecular Cell Physiology Research Group, Inje University College of Medicine, Busan, 614-735, Republic of Korea
Three-dimensional ZnMn 2 O 4 / porous carbon framework from petroleum asphalt for high performance lithium-ion battery

Three-dimensional ZnMn2O4/porous carbon framework (3D ZnMn2O4/PCF) was prepared from petroleum asphalt via template synthesis of 3D porous carbon framework (PCF) and subsequent incorporation with ZnMn2O4. As the anode material of lithium-ion batteries, 3D ZnMn2O4/PCF exhibits a high reversible capacity of 760 mAh g 1 at 100 mA g 1 and superior rate capability (ca. 500 mAh g 1 at 800 mA g ), which can be ascribed to the superior electrical conductivity of carbon framework and its dimensional confinement on ZnMn2O4 nanoparticles. 3D ZnMn2O4/PCF with ZnMn2O4 nanoparticles well dispersed and firmly anchored on the inner wall of PCF can stably exist during the insertion and desertion of Li ions, ensuring the high rate and long lifespan performances. The present study demonstrates an effective and scalable strategy to solve the long-term cycling difficulty for metal oxide electrodes and help us to understand the roles of dimensional confinement involved in electrodes. Meanwhile, the present study makes it possible to fulfill the high-valued application of petroleum asphalt and other kinds of heavy oil. ã 2015 Elsevier Ltd. All rights reserved.
Callus Induction and Plant Regeneration on Optimization of the Culture Conditions in Jow Haw Rice ( Oryza Sativa L . )

The objective of this study was to develop an efficient protocol for optimum callus induction and regeneration of Jow Haw (Oryza sativa L.). MS (Murashige and Skoog) and NB (Nitch and Nitch) media supplemented with 0.5 mg/l NAA (α-Naphthaleneacetic acid) and 0.5, 1, 2, 3 and 5 mg/l 2,4-D (2,4-Dichlorophenoxyacetic acid) in different concentrations were used for callus induction. The callus induction frequencies were 90-100% on NB medium containing 3 mg/l 2,4-D for 4 weeks. The maximum mean size of callus was 181.76 mm 3 and mean fresh weight of callus was 0.2552 g. For plant regeneration the callus were cultured on MS and NB media containing with 0.5 mg/l NAA and different concentrations of 1, 2 and 3 mg/l BAP (6Benzylaminopurine). The highest regeneration frequency (100%) was grown on MS medium containing with 2 mg/l BAP in 5.2 g/l phytagel. Complete plantlets were regenerated in 6 weeks. When the plantlets regeneration were be strong. Then transferred to the sterile soil into pots
INDIGENOUS PROTECTED AREAS AND ICCAS : COMMONALITIES , CONTRASTS AND CONFUSIONS

Indigenous Protected Areas (IPAs) in Australia and ICCAs (an acronym derived from ‘Indigenous and Community Conserved Areas’, originally used to summarize ‘Indigenous peoples’ protected areas, Indigenous peoples’ conserved territories and community conserved areas’) internationally are both areabased designations that provide contemporary expressions of the ancient and ongoing relationships between Indigenous peoples (and also non-Indigenous local communities in the case of ICCAs) and their local environments – with a particular emphasis on conservation outcomes. This paper explores commonalities and contrasts between IPAs and ICCAs, seeking to clarify their meanings and applications, and also to contribute to debate on the concepts of ‘conserved areas’ and ‘protected areas’ within the IUCN conservation lexicon. The paper describes the evolution of the IPA concept from being based on Indigenous legal ownership (tenure) of land to being based on Indigenous ‘Country’ (traditional clan estates), irrespective of current legal ownership. This is contrasted with the evolution of the ICCA concept that currently only applies to Indigenous peoples’ and local communities’ territories and areas where major decision-making authority has been retained by the respective Indigenous peoples or local communities. Proposals are made to clarify the use of the terms ‘protected area’ and ‘conserved area’, particularly in the context of respecting the rights of Indigenous peoples and local communities to assign their own designations to their respective territories and areas.
MicroRNA-133 inhibits the growth and metastasis of the human lung cancer cells by targeting epidermal growth factor receptor.

PURPOSE Accounting for 25% of all cancers and 20% of the cancer related-mortality, lung cancer is one of the devastating types of malignancies. The main obstacles for successful lung cancer manipulation include late diagnosis, dearth of safer chemotherapy and lack of potent therapeutic targets. Evidence indicates that microRNAs (miRs) may prove essential therapeutic targets for the management of deadly diseases, including cancer. Herein the role of miR-133 was investigated in lung cancer and the therapeutic potential of miR-133 was explored. METHODS qRT-PCR was used for expression profiling of miR-133 and epithermal growth factor receptor (EGFR) in normal lung cell line MRC5 and lung cancer cell lines SK-MES-1, A549, A427 and DMS-53. Cell Counting Kit-8 (CCK8) assay was used to monitor the proliferation rate. Flow cytometry was used for cell cycle analysis. Apoptosis was examined by DAPI and annexin V/propidium iodide (PI) staining. TargetScan analysis was performed to identify the potential target of miR-133 and western blot analysis was done to estimate the proteins' expression. RESULTS miR-133 was significantly (p<0.05) downregulated in lung cancer. Overexpression of miR-133 in A549 lung cancer cells caused significant (p<0.05) inhibition of their proliferation via activation of apoptotic cell death, suggestive of the tumor suppressive role of miR-133. In addition, miR-133 overexpression also resulted in significant (p<0.05) suppression of A549 cell migration and invasion. TargetScan analysis indicated EGFR to be the potential target of miR-133 in A549 cells. Analysis of EGFR expression in lung cancer cell lines showed up to 4.6 fold upregulation of EGFR. However, miR-133 overexpression resulted in downregulation of EGFR expression. Furthermore, silencing of EGFR also resulted in inhibition of proliferation, migration and invasion of A549 cells. However, overexpression of EGFR could nullify the tumor suppressive effects of miR-133, indicating EGFR inhibition is essential for the miR-133-mediated inhibitory effects on A549 cell proliferation. CONCLUSION Taken together, miR-133 acts as a tumor suppressor and may prove essential in the management of lung cancer.
Influence of cultural media on the growth of Fusarium moniliforme causing foot rot disease

Foot rot of rice caused by Fusarium moniliforme (Fusarium verticillioides) has become a major problem on certain cultivars of rice under Punjab conditions. The pathogen produces different types of symptoms (elongation, stunting or both and death of plants) in nursery as well as in field. The influence of the cultural media on morphological, cultural characteristics and growth rate of F. moniliforme on four different media: Potato dextrose agar (PDA), Soil Extract Agar (SEA), Spezieller Nahrstoffarmer (SNA) and Water Agar (WA) were studied and macro-conidial features were observed on carnation leaf Agar (CLA) medium. The pathogen was isolated from the foot rot infected Basmati plants, collected from different agro-ecological zones of Punjab. The colony color in PDA and SEA was varied between whitish to pinkish whereas in SNA and WA media it was observed to be white. The maximum colony diameter of Fusarium moniliforme was observed on PDA with 82.33 mm diameter and growth rate of 25.72 mm/ 48hrs, followed by SEA with colony diameter of 79.67 mm and growth rate of 19.65 mm/48hrs. Poor growth rate was observed on SNA with 16.55mm/ 48hrs growth rate and 47.98mm colony diameter. Lowest was observed on Water Agar (WA) with 35 mm colony diameter and 6.5mm/ 48hrs growth rate. Mycelial growth was dense and fluffy on both PDA and SEA. Moderate and sparse to thin growth on SNA medium was observed. No chlamydospores were observed on all the media under study. Sporulation was highest in SNA (6 x10 spores/ ml), followed by SEA (5.7 x10 spores/ ml) and PDA (4 x10 spores/ ml). But the culture show poor sporulation in WA.
Fachrichtung Mathematik Preprint Nr . 392 Galerkin-Petrov approach for the Boltzmann equation

In this work, we we propose a new Galerkin-Petrov method for the numerical solution of the classical spatially homogeneous Boltzmann equation. This method is based on an approximation of the distribution function by associated Laguerre polynomials and spherical harmonics and test an a variational manner with globally defined three-dimensional polynomials. A numerical realisation of the algorithm is presented. The algorithmic developments are illustrated with the help of several numerical tests.
Assessment of physical, mechanical, and biological properties of bamboo plastic composite made with polylactic acid

The effects of different mixing, bamboo mesh size and heat treatment on the physical and mechanical properties and biodegradability of a polylactic acid (PLA) composite were determined. The results indicated that this composite exhibited high strength in all mechanical properties examined, except hardness using the pure polymer (PLA). The mesh size of the bamboo flour and heat treatment had considerable effects on all tests expect the decay resistance. The water absorbance and thickness swelling of the PLA composite was reduced to nearly zero after 3000 hours immersion in water. Moreover, the fungal decay test results demonstrated that PLA was highly resistant to both Basidiomycetes and Ascomycetes fungi. The brown rot fungi, however, produced an extensive mass loss in the composite composed of different levels of bamboo flour.
Caring for caregivers: challenges facing informal palliative caregivers in Western Kenya

4 Background . 5 Literature Review . 7 Problem Statement . 9 Objectives . 9 Methodology . 10 Setting . 10 Population . 11 Methods. 11 Ethics . 12 Results . 12 Demographics . 12 Interviews . 15 Financial factors . 16 Medical factors . 18 Emotional/psychosocial factors . 19 Cultural/societal factors . 20 Interventions . 21 Discussion . 21 Limitations and Future Suggestions . 23 Conclusion and Recommendations . 23 References . 25 Appendices . 28 Appendix A: Consent Forms . 28 Appendix B: Interview Guides . 34
ICT Services and Robotics : The SocialRobot Solution *

Most elderly people prefer to live independently, for as long as possible, in their preferred environment. Nowadays, the predominant care model for supporting elders living alone at home is based on informal carers’ assistance (i.e., relatives, friends, neighbours, etc.). Considering the shifting demography of the elderly population, this model is expected to pose major challenges both in the economy as well as the society. To address these challenges, there is growing attention for assistive technologies to support seniors stay active and independent for as long as possible in their preferred home environment. ICT and Robotic systems are among those initiatives. The work presented in this paper is based on the context of the Social Robot project and focuses on presenting the integration of ICT and Robotic technologies as a trigger towards ‘Positive Ageing’. ‘Positive Ageing’ seeks to take a balance approach between addressing the opportunities and challenges of an ageing society rather than seeing the increase in longevity as a burden and a threat.
Study of β-phase development in spin-coated PVDF thick films

A study was conducted to ascertain the effect of variation in spin speed and baking temperature on β-phase content in the spin-coated poly(vinylidene fluoride) (PVDF) thick films (∼4−25 μm). Development of β-phase is dependent on film stretching and crystallization temperature. Therefore, to study the development of β-phase in films, stretching is achieved by spinning and crystallization temperature is adjusted by means of baking. PVDF films are characterized using Fourier transform infrared spectroscopy, X-ray diffraction, differential scanning calorimetry, and scanning electron microscopy. It is observed that crystallization temperature lower than 60◦C and increase in spin speed increases the β-phase content in PVDF films. Crystallization temperature above 60◦C reduces β-phase content and increases α-phase content. It was also observed that viscosity of the PVDF solution affects the β-phase development in films at a particular spin speed.
THE EFFECT OF NON-UNIFORM IONOSPHERIC CONDUCTIVITY ON STANDING MA

We look at time-de~ndent normal mode solutions to the Alfven wave equation in a uniform magnetic field, between planar ionospheres. In particular, the effect of sharp gradients in ionospheric conductivity on the spatial and temporal structure of the waves is considered. We show that the electric field of the wave must always be perpendicuiar to any conductivity discontinuities present, and that this is achieved by the generation of circularly polarized Affven waves at the discontinuity. The results are applied to an ionospheric strip of high conductivity; this being relevant to PiB.
Multi-level interactions and land ownership in 1930 ’ s Spain

We analyse the process of recovering common lands i itiated by the Spanish Government during the Second Spanish Republic (1931 6). Requests for the reinstatement of commons submitted to the Institute of Agrarian Reform by Spanish municipalities from nearly all the country’s provin ces reflect a huge variety of circumstances, as regards both the way these lands had been privatised and the agents and social groups involved in their recovery. The c ases investigated between 1931 and 1936 allowed reversing the trend in property rights over common lands that had prevailed in many Spanish municipalities since the 18 and 19 centuries (and even earlier).
The effect of overtraining on serum leptin levels in women national wrestlers

Purpose: Weight control and weight loss during the periods of wrestling competitions are attached great importance -in order to be successful in wrestling. Leptin hormone level is known to play an important role in the control of body weight. For this reason, the purpose of this study was to investigate the effect of substantial weight loss on serum leptin levels of women wrestlers during competition periods. Material and Methods: Twenty-five women wrestlers who trained for 2015 European Championship from Turkish National Wrestling Team and 26 sedentary women were recruited voluntarily for this study. Serum leptin levels of wrestlers in the experimental group and sedentary women in the control group were measured after overnight fasting before and after 21 days training camp of 2015 European Championship. Results. Statistically significant difference was found in the direction of decrease in body weight, body mass index (BMI), glucose, insulin, cholesterol, triglyceride, LD, VLDL and leptin parameters and increase in HDL parameters before and after training camp in the experimental group ( p < .05 ). There was a statistically significant difference in leptin levels between the control group and women wrestlers ( p < .05 ). There was also a statistically significant difference in leptin levels of wrestlers before and after training camp ( p < .05 ). Conclusion. As a result, the data obtained in the study indicate that intense wrestling trainings in camping period brought about weight loss and decreased leptin levels.