Miracle-dz/UniFAR-FTUs huggingface dataset:
Alveolar Bone Grafting in Patients with Complete Clefts: A Comparative Study between Secondary and Tertiary Bone Grafting

Objective: This investigation evaluated the results of alveolar bone grafting in patients with complete clefts, comparing secondary alveolar bone grafting (during the mixed stage of dentition) versus tertiary bone grafting (after completion of the second stage of dentition). Design: This was a retrospective study. Of 140 osteoplasties, which all were operated according to the same standardized surgical technique, a clinical and roentgenological follow-up investigation was carried out in a collective of 85 osteoplasties. Clinically we searched for oronasal fistulae, assessed the periodontal status, determined the extent of the gingival attachment in the area of the osteoplasty, and searched for vertical growth disturbances in the area of the osteoplasty. Roentgenologically the height of the alveolar bone in the former clefted area was ascertained. Setting: Records were obtained from a clinical and radiological study of the Department of Oral and Maxillofacial Surgery of the Medical University of Hannover (Germany). Interventions: All patients were operated with the same standardized surgical method. The osteoplastic bridging of the alveolar cleft was performed via a vestibular gingival marginal incision and exclusively by grafting of cancellous bone from the iliac crest. Results: The best results of alveolar bone grafting in cases of secondary osteoplasty were obtained when the lateral incisor or canine had grown into the transplant and had led to a functional stress of the transplanted bone. Approximately good results were to be found in tertiary osteoplasty when the transplanted bone had been stressed functionally through a dental implant. Comparing the secondary with the tertiary osteoplasty, there was a trend of lower resorption in secondary osteoplasty. Conclusions: Secondary osteoplasty should represent an integral component of any concept for the comprehensive treatment of patients with cleft lip and palate.
A LONG-TERM STUDY IN URBAN ROME

The breeding biology of the Tawny Owl (Strix aluco) was studied in northern and central Europe specifically focusing on the influence of food abundance on clutch s•ze and productivity of young (Southern 1970, Wendland 1984). Baudvin (1990) fbund a remarkable positive correlation belween the reproductive output of Tawny Owls and the percentage of woodland rodents in the diet of pairs in central France. Annual fluctuations in Tawny Owl breeding success were directly linked to the abundance of woodland rodents, especially the yellow-necked mouse (Apodemus flavicollis), the main prey of this owl in woods and mixed farmlands (Wendland 1984, Baudvin 1990, Jedrze. jewski et al. 1994). Moreover, alternative prey (e.g., birds and amphibiaus) increased in diet in low mouse years (Plesnik and Dusik 1994). Cyclic fluctuations •n populations of rodent prey is probably the main factor affecting •I:awny Owl productivity, but other fhctors, such as weafimr conditions, could be also involved (Kostrzewa and Kostrzewa 1990, Gil-Delgado et al. 1995, Penteriani 1997). In Mediterranean areas, very few studies have fbcused on the study the aunual variations in the breeding sin> cess of any rapmr (Gil-Delgado et al. 1995). The aim of this study was to assess the long-term breeding success of' Tawny Owls in a Mediterranean urban area, checking for variations, if any, in productivity of young, and comparing them to the breeding t)erfbrmance of other areas in Eu-
Acoustic Rhinometric Measurements of Changes in Velar Positioning

Acoustic rhinometry as a means to detect changes in velar position was examined in this study. Videofluoroscopic recordings were made of two normal speakers maintaining velopharyngeal open and velopharyngeal closed (silent /f/) targets. Simultaneous acoustic rhinometric recordings were made during the production of each stimulus. Determinations of changes in velar positioning during the closed samples were made from fluoroscopic recordings and compared to nasal cavity-nasopharynx changes detected by rhinometry. The excellent agreement between the measures from the two procedures (less than 1 cm) indicates that acoustic rhinometry is capable of detecting changes in velar positioning during “silent” speech. Implications for assessment and future research are discussed.
Craniofacial Growth in Bilateral Cleft Lip and Palate: Ages Six Years to Adulthood

The purpose of the study was to localize the characteristic craniofacial abnormalities in young children with complete bilateral cleft lip and palate, to average their growth changes, and to compare all these to observations from a normative sample. A longitudinal sample of 30 males with complete bilateral cleft lip and palate was obtained from the files of the Craniofacial Center at The Hospital for Sick Children, Toronto. An age-matched noncleft control sample was selected from the Burlington Orthodontic Research Center. All individuals had lateral cephalometric radiographs at approximately 6 years, 12 years, and as adults. These were analyzed by cephalometrics and by tensor biometrics. The results of the two methods of analysis were in agreement and tended to complement each other. In the cleft sample, there was little cleftinig effect on the midline structures of the cranial base; the premaxilla was initially protruded but became normal in the adult; the nasal bone was longer and more protruded; the posterior maxillary segments were hypoplastic and the bony pharynx narrower; there was overeruption of the posterior teeth; and the mandibular gonial area was smaller.
Factors influencing citizens’ co-production of environmental services: a multi-level analysis

Drawing on the literature on public service co-production, we examine the individuallevel factors associated with people’s pro-environmental behaviours. We also explore the role that local government-level factors play in shaping those behaviours. Multilevel analyses of data from a survey of citizens across the twenty-two local governments in Wales indicate that individuals who are more altruistic and have high levels of selfefficacy, are more likely to ‘co-produce’ environmental services through activities such as recycling, volunteering and ‘green’ consumerism. In addition, women, rural-dwellers, university graduates and middle-aged individuals exhibit more pro-environmental behaviours. Further analysis suggests that environmental co-production is more prevalent in areas with a high degree of compatibility between local public services and citizens, but poorer quality and cheaper services. Stronger backing for ‘green’ political representation is also important. The theoretical and practical implications of our findings are discussed.
DYNAMIC MODEL OF NEW PRODUCT LAUNCH IMPACT ON STOCK MARKET PARTICIPANTS

The instant access to global information and just as fast responses to the information result in very fast development of communication possibilities and information spreading. The paper addresses spreading information about a new product in a way similar to the principle of virus spreading in epidemiology. We will introduce a mathematical model of signal spreading about a new product in the stock market environment, considering the time delay and inspired by the virus dynamics theory. The mathematical model has been set up from the point of view of the investors ́ behaviour and analysed in terms of the time delay influence. The situations demonstrated confirm that the signal of the newly introduced product will have an effect on the stock market behaviour over a certain period but in the long-term perspective its influence disappears. The model solvability is analysed and the solution is demonstrated on a particular example.
CIient satisfaction: Why bother?

The literature on client satisfaction with health care services is considerable, but much is related to the period before the introduction of health care reforms of recent years. Interest in these areas has been sporadic, possibly because of the biases associated with this type of research. In the current climate of reduced health care resources and health care reforms, the findings from client satisfaction studies are increasingly being viewed as an integral component of strategic management and program monitoring. In this paper the main problems are discussed, with particular reference to alcohol and drug (AD) services, and strategies to enhance satisfaction are suggested. The need for routine studies conducted with standardized instruments with good psychometric properties is discussed.
Effect of Cuspid Positioning in the Cleft at the Time of Secondary Alveolar Bone Grafting on Eventual Graft Success

This investigation was to determine the relationship between the success of secondary alveolar bone grafting and the position of the permanent cuspid relative to the cleft at the time of grafting. In this retrospective study utilizing periapical radiographs taken on cleft patients to evaluate bone grafting results, the subjects were patients treated at the Lancaster Cleft Palate Clinic, a private institution specializing in the care of cleft patients. Sixty-seven patients (20 BCLP; 47 UCLP) were selected for this study based on availability of quality radiographs and a minimum of 6-month post-surgical follow-up. All patients underwent alveolar bone grafting (mean age, 10 years 7 months). Presurgical radiographs were taken within 3 months of the operation. Post-surgical radiographs were taken to evaluate the outcome of grafting (mean follow-up, 2 years 10 months). Radiographs were traced and digitized on a total of 86 cleft sites. Presurgically, a ratio was used to determine the amount of cuspid crown emerged through the alveolus into the cleft site relative to the anatomic cuspid-crown length. Post-surgically, ratios of bone support for the teeth mesial and distal to the cleft were established by dividing the amount of root covered by bone by the anatomic root length. Ratios expressing the height of alveolar crest relative to the cementoenamel junction (CEJ) of adjacent teeth and amount of alveolar notching relative to the mesial tooth root length were also evaluated. Linear regressions of each of the five ratios of graft outcome on the cuspid-eruption ratio were done. No significant correlations could be found between final graft success and the amount of cuspid crown exposed in the cleft at the time of grafting. Cuspid position could not be shown to be a significant factor in determining graft success.
PPA_A_198967 729..738

Omid Moradi Iman Karimzadeh Dorna Davani-Davari Mojtaba Shafiekhani Mohammad Mahdi Sagheb 1Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran; 2Department of Clinical Pharmacy, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran; 3Nephrology-Urology Research Center and Department of Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Purpose: Ever increasing number of patients who receive kidney transplantation as a therapeutic option, approaches to increase graft survival as well as to identify factors that reduce the treatment outcomes should be taken into account. One of the heightened concerns after transplantation is non-adherence to immunosuppressive medications, which increases the risk of kidney failure or even rejection. The aim of this study was to evaluate factors associated with immunosuppressant medications adherence in kidney transplant recipients. Patients and methods: Data were collected from 100 eligible kidney transplant patients referring to Shiraz Motahhari clinic and a private office of an attending nephrologist during 18 months. Adherence to immunosuppressive medications was assessed by Basel assessment of adherence to immunosuppressive medication scale at 2 time points. Results: According to the findings, 55% of patients did not adhere to their posttransplantation immunosuppressive medications. The rate of adherence to immunosuppressive medications was not either statistically or clinically significant between time points zero and six months. None of the investigated factors including demographic, clinical and social-economical-cultural factors were significantly associated with patients' adherence to immunosuppressive regimen. Furthermore, there was no statistically significant association between immunosuppressive medication adherence and acute kidney rejection. Conclusion: The rate of non-adherence to immunosuppressive medications was high. These data can be exploited by both physicians and policymakers to improve the rate of adherence to immunosuppressive medications amongst kidney transplant recipients.
ANTIGENIC DETECTION OF FELINE PANLEUKOPENIA VIRUS IN LOCAL BREED CATS AT TANGAIL DISTRICT IN BANGLADESH

Feline panleukopenia virus (FPV) is highly contagious viral disease of cat, responsible for high mortality but to our knowledge, there is not report for the antigenic detection of FPV in Bangladesh. Therefore, a cross-sectional survey was carried out for the antigenic detection of FPV in 58 randomly selected cats consisted of 46 pet and 12 stray cats at Tangail district in Bangladesh during May to October 2009. Rectal swab samples were collected from all cats and tested by commercial rapid RapiGEN ® Feline Parvo Virus (FPV) Ag Test Kit (RapiGEN Inc., Korea) following the manufacturer’s instructions. This study revealed that 22.41% of cats were found positive for FPV. The infection was more prevalent in cats less than 2 months (29.62%) compared with cats of age group 2 months to 1 year (21.43%) and age group > 1 year (11.76%) and higher prevalence of FPV was recorded in female (26.92%) than those of male (18.75 %) cats. A higher prevalence of FPV was recorded in stray cats (41.67%) than that of pet cats (17.39%) and in diarrhoeic cats (29.73%) than those of non-diarrhoeic cats (9.52%). There were no significant relationship with test results and variables. The knowledge of the status of feline panleukopenia infection in cats of study area would be helpful for initiating preventive measures.
The Evidence-Based Epidemiology of HCV-Associated Kidney Disease

Novel information supports a definite link between hepatitis C virus (HCV) infection and chronic kidney disease (CKD) in the general population. HCV is associated with a large spectrum of histopathological lesions in both native and transplanted kidneys. Kidney disease is probably uncommon in HCV-infected patients even if its exact frequency remains unknown. The most common HCV-associated nephropathy is type I membranoproliferative glomerulonephritis, usually in the context of type II mixed cryoglobulinemia. Controversial information exists on the relationship between positive HCV serology and CKD but several surveys at population-based level suggest that infection with HCV per se is associated with an increased risk of having or developing renal insufficiency or proteinuria. According to a novel metaanalysis of observational studies (4 clinical studies, 93,919 unique individuals), positive HCV serology was an independent and significant risk factor for proteinuria; the summary estimate for adjusted relative risk is 1.55 with a 95% confidence interval (CI) of 1.14; 2.12, p = 0.0001 (random-effects model). The mechanisms of these associations appear complex, but both viral and non-viral processes have been implicated. Prospective studies are needed to fully characterize the exact impact of chronic HCV infection on kidney function trajectories over time.
Cervical Root Resorption in Two Patients with Unilateral Complete Cleft of the Lip and Palate

Objective: Case reports on cervical root resorption in patients with complete cleft of the lip and palate are scarce. Moreover, cervical root resorption is sometimes diagnosed several years after a combined orthodontic and surgical therapy in patients with cleft. In this article a review of the literature is presented, and a description and the management of the cervical lesion is provided. An additional objective of this report is to advocate for alveolar bone grafting before the age of 12 years while the vulnerable cervical region of the teeth adjacent to the cleft defect is still protected by a thick layer of bone.
Pressure-Flow Measurements for Selected Nasal Sound Segments Produced by Normal Children and Adolescents

Objective: The purpose of this prospective study was to: (1) report simultaneous oral-nasal pressures, nasal airflow rates, and velopharyngeal orifice areas for nasal sounds produced by children and adolescents; (2) determine whether data could be statistically classified by age, sex, or utterance type; and (3) provide guidelines for determining typical from atypical productions. Participants: The study involved 56 subjects, with two boys and two girls representing each age from 5 to 18 years. Subjects had no history of speech therapy, were judged as having normal speech and resonance at the time of testing, and had no upper respiratory tract infections or allergies at the time of testing. Methods: All subjects repeated /ma/ and ‘‘hamper’’ at normal pitch and loudness after an examiner model. Mean oral-nasal pressures, nasal airflow rates, and velopharyngeal orifice areas were calculated for each subject’s utterances. A discriminate function analysis determined whether data could be grouped by age and sex. Results: Significant differences in mean data for age groups of 5 to 9 years, 10 to 13 years, and 14 to 18 years were observed. Data showed decreases in pressures and increases in nasal airflow and orifice areas with age. Variability in pressure stayed consistent or decreased with age, but variability in nasal airflow and orifice areas increased with age. Conclusions: We propose a scheme for categorizing velopharyngeal function for oral and nasal sound production to be used in clinical testing.
RANDOMIZED SKETCHING ALGORITHMS FOR LOW-MEMORY DYNAMIC

This paper develops a novel limited-memory method to solve dynamic optimization problems. The memory 4 requirements for such problems often present a major obstacle, particularly for problems with PDE constraints such as optimal 5 ﬂow control, full waveform inversion, and optical tomography. In these problems, PDE constraints uniquely determine the state 6 of a physical system for a given control; the goal is to ﬁnd the value of the control that minimizes an objective. While the 7 control is often low dimensional, the state is typically more expensive to store. 8 This paper suggests using randomized matrix approximation to compress the state as it is generated and shows how to 9 use the compressed state to reliably solve the original dynamic optimization problem. Concretely, the compressed state is 10 used to compute approximate gradients and to apply the Hessian to vectors. The approximation error in these quantities is 11 controlled by the target rank of the sketch. This approximate ﬁrst-and second-order information can readily be used in any 12 optimization algorithm. As an example, we develop a sketched trust-region method that adaptively chooses the target rank 13 using a posteriori error information and provably converges to a stationary point of the original problem. Numerical experiments 14 with the sketched trust-region method show promising performance on challenging problems such as the optimal control of an 15 advection-reaction-diﬀusion equation and the optimal control of ﬂuid ﬂow past a cylinder. 16
Clinical Characteristics and Outcomes of Patients with Heart Failure Hospitalized in the Clinical Emergency Hospital of Bucharest

Caracteristicile clinice aei evoluaia pacienailor cu insuficienaa cardiaca internaai in Spitalul Clinic de Urgenaa Bucureaeti Obiectivul studiului a fost de a investiga caracteristicile clinice, management-ul aei evoluaia pacienailor cu insuficienaa cardiaca cronica internaai consecutiv in Clinica de Medicina Interna a Spitalului Clinic de Urgenaa Bucureaeti, pe o perioada de 8 luni (1 ianuarie 2012 31 august 2012). Metoda: Studiul a inclus 436 pacienai. Au fost analizate datele din baza de date a spitalului. La fiecare pacient s-a efectuat examen obiectiv, EKG, teste de laborator, ecocardiografie 2-D aei alte teste imagistice. Rezultate: Vârsta medie a pacienailor a fost de 59.2 ±17.4 ani. Distribuaia in funcaie de sex: 233 (53,4%) barbaai aei 203 (46,6%) femei. Hipertensiunea arteriala a reprezentat cauza principala a insuficienaei cardiace (45.92%), urmata de boala cardiaca ischemica (38.22%), diabetul zaharat (16.51%), bolile valvulare aei alte cardiomiopatii. 46% din pacienai au fost in ritm sinusal aei 44.50% in fibrilaaie atriala. Principalele comorbiditaai au fost: 31.6% dislipidemie, 22% boala cronica de rinichi aei 5.3% boala arteriala periferica; 11.7% din pacienai au avut hipertensiune pulmonara. Durata medie de spitalizare a fost de 7 zile. Mortalitatea intraspitaliceasca a fost de 5.9%. Rata de re-internare la 90 zile, datorita insuficienaei cardiace, a fost de 6.7%. Diureticele parenterale au fost administrate la 69.21% din pacienai; 82.55% din pacienai au primit inhibitori ai enzimei de conversie sau blocante ale receptorilor de angiotensina, 62.11% beta-blocante, 39.24% antagoniaeti de aldosteron aei 29.36% inotrope in timpul spitalizarii. Concluzii: Cea mai frecventa cauza a insuficienaei cardiace in grupul de studiu a fost hipertensiunea arteriala, urmata de boala coronariana. Aproape 2/3 din pacienai au primit diuretice parenterale pentru ameliorarea simptomelor; majoritatea au primit inhibitori ai enzimei de conversie aei blocante ale receptorilor de aldosteron. Pentru prevenaia trombembolismului la pacienaii cu fibrilaaie atriala, acenocumarol-ul a fost medicamentul preferat. Cuvinte cheie: insuficienaa cardiaca, comorbiditaai, rata internarilor Clinical Characteristics and Outcomes of Patients with Heart Failure Hospitalized in the Clinical Emergency Hospital of Bucharest
Prenatal and Postpartum Depression among Low-Income Dominican and Puerto Rican Women

This longitudinal study examined depression symptoms among pregnant, low-income, urban Latinas, primarily Puerto Ricans and Dominicans, receiving obstetrical services in community health centers. In all, 106 women were interviewed in late pregnancy, 47 were interviewed again 2 to 3 weeks postpartum, and 42 three months postpartum. Elevated levels of depressive symptoms were evident in 53% of the original sample. Across time, depressive symptoms decreased significantly; however, a decreased score was strongly related to number of negative life events. Social support scores were minimally related to depressive symptomatology. Service recommendations based on these findings include conducting third-trimester assessments of life events experienced during the past year and screening for depression to better identify women at risk of late pregnancy to postpartum–persistent depressive symptoms. More research and clinical attention on dysphoric states in pregnant Latinas and understanding the consequences of impaired perinatal mental health on maternal well-being and infant outcomes are needed.
The Clinical and Economic Burden of Irritable Bowel Syndrome

Irritable bowel syndrome (IBS) is one of the most frequently diagnosed gastrointestinal disorders in primary care and gastroenterology practices. Research findings have pro- vided a greater understanding of the burden of IBS. Irritable bowel syndrome can sub- stantially impact an individual's ability to function socially and professionally. The magnitude of impairment in quality of life is directly related to the frequency and sever- ity of bowel symptoms, the presence of extraintestinal manifestations of IBS, and psy- chological symptoms. The total direct and indirect costs of IBS, estimated at $30 billion annually in the United States, are higher than for chronic conditions such as asthma. Findings demonstrating the clinical, humanistic, and economic burdens of IBS illus- trate the need for a multidimensional approach to this illness to establish appropriate patient management strategies and reduce the economic burden of IBS to the patient, employer, and healthcare system.