Miracle-dz/UniFAR-FTUs huggingface dataset:
Bayesian blind equalization of time-varying frequency-selective channels subject to unknown variance noise

We present in this article a novel particle-filter-based blind equalization algorithm suitable for FIR time-varying frequency-selective communication channels corrupted by unknown variance additive Gaussian noise. The proposed method is fully Bayesian, integrating out the unknown parameters via an original recursive method, unlike previous approaches that rely on suboptimal plug-in estimates. We verify via numerical simulations that the proposed method's performance approaches that of the trained MAP equalizer, exceeding that of the linear least squares Kalman equalizer for medium to low noise levels.
An Extracellular Matrix-Associated Zinc Metalloprotease Is Required for Dilauroyl Phosphatidylethanolamine Chemotactic Excitation in Myxococcus xanthus

ABSTRACT An extracellular matrix connects bacteria that live in organized assemblages called biofilms. While the role of the matrix in the regulation of cell behavior has not been extensively examined in bacteria, we suggest that, like mammalian cells, the matrix facilitates cell-cell interactions involved with regulation of cohesion, motility, and sensory transduction. The extracellular matrix of the soil bacterium Myxococcus xanthus is essential for biofilm formation and fruiting body development. The matrix material is extruded as long, thin fibrils that mediate adhesion to surfaces, cohesion to other cells, and excitation by the chemoattractant dilauroyl phosphatidylethanolamine. We report the identification of a putative matrix-associated zinc metalloprotease called FibA (fibril protein A). Western blotting with FibA-specific monoclonal antibody 2105 suggests extensive proteolytic processing of FibA during assembly into fibrils, consistent with the autoprocessing observed with other members of the M4 metalloprotease family. Disruption of fibA had no obvious effect on the structure of the fibrils and did not inhibit cell cohesion, excitation by dioleoyl phosphatidylethanolamine, or activity of the A- or S-motility motors. However, the cells lost the ability to respond to dilauroyl phosphatidylethanolamine and to form well-spaced fruiting bodies, though substantial aggregation was observed. Chemotactic excitation of the fibA mutant was restored by incubation with purified wild-type fibrils. The results suggest that this metalloprotease is involved in sensory transduction.
[Gender differences in the neurocognitive components of depression].

UNLABELLED The clinical symptoms of major depression are paralleled by typical neurocognitive deficits. Our aim was to investigate the gender differences in neurocognitive impairment in patients with major depressive disorder. METHODS 96 patients with acute major depressive disorder meeting DSM-IV criteria participated in our study. Depression was assessed by the Montgomery-Asberg Depression Rating Scale, the Hamilton Depression Scale and the Beck Depression Inventory. We measured neurocognitive functions associated with verbal learning and memory (Rey Auditive Verbal Learning Test), visual reconstruction and recall (Rey-Osterreith Complex Figure Test), selective attention, executive functions and inhibitory control (Trail Making Test, Stroop Test). RESULTS Depressive patients performed significantly worse than controls in all tests. We found no gender differences in any of the tests in the control group. Depressed women performed significantly worse on tests of cognitive interference threshold compared to depressed men (Stroop III). Depressed women performed significantly worse compared to depressed men in the test of visual recall (Rey-Osterreith Complex Figure Test). CONCLUSION Depressed patients performed worse in all tests of neurocognitive function compared to healthy controls. Depressed women performed significantly worse compared to depressed men in tests of visuospatial recall and cognitive interference. In the light of neuroimaging studies our results suggest that in the background of gender differences we observed in depressed patients lateralisation of hippocampal function may play an important role.
The Concept of Quality of Life

Despite the fact that, in the current debate, quality of life is depicted as something very desirable, its concept is seldom specified. With regard to previous research into welfare and quality of life, a model of an overall concept of quality of life is presented here. The theoretical analysis ends in and is woven into an empirical application. The application consists of a prospective longitudinal investigation of alcoholics who receive disability pensions. This report is the first in a planned series from the research project “Abuse of alcohol — Disability pension — Quality of life”.
Using Freeware Resources to Analyse Sentiments in Social Media

The social media is gaining a lot of importance among businesshouses, academicians, medical practitioners, politicians, among others, due to its role in creating awareness about products, services, and socio-political views. The end users of these products, services, and views provide their feedbacks in the form of comments. An accurate determination of the sentiments of end users is crucial in designing policies and plans for products and services in future. As the processing power and storage capacities of computers have increased several folds, researchers can focus more on the accuracy of sentiment detection than consumption of computational resources. In this paper, we are applying a set of heuristics to analyse sentiments using freely available dictionary resources and open source tools. We have tested these heuristics over a large data set collected from standard sources. The experimental results are promising and opening new research directions in dictionary-based sentiment analysis.
Improving bystander defibrillation in out-of-hospital cardiac arrests at home

Aims: Most out-of-hospital cardiac arrests occur at home with dismal bystander defibrillation rates. We investigated automated external defibrillator coverage of home arrests, and the proportion potentially reachable with an automated external defibrillator before emergency medical service arrival according to different bystander activation strategies. Methods and results: Cardiac arrests in homes (private/nursing/senior homes) in Copenhagen, Denmark (2008–2016) and registered automated external defibrillators (2007–2016), were identified. Automated external defibrillator coverage (distance from arrest to automated external defibrillator) and accessibility at the time of arrest were examined according to route distance to nearest automated external defibrillator and emergency medical service response time. The proportion of arrests reachable with an automated external defibrillator by bystander was calculated using two-way (from patient to automated external defibrillator and back) and one-way (from automated external defibrillator to patient) potential activation strategies. Of 1879 home arrests, automated external defibrillator coverage ≤100 m was low (6.3%) and a two-way bystander could potentially only retrieve an accessible automated external defibrillator before emergency medical service in 31.1% (n=37) of cases. If a bystander only needed to travel one-way to bring an automated external defibrillator (≤100 m, ≤250 m and ≤500 m), 45.4% (n=54/119), 37.1% (n=196/529) and 29.8% (n=350/1174) could potentially be reached before the emergency medical service based on current automated external defibrillator accessibility. Conclusions: Few home arrests were reachable with an automated external defibrillator before emergency medical service if bystanders needed to travel from patient to automated external defibrillator and back. However, nearly one-third of arrests ≤500 m of an automated external defibrillator could be reached before emergency medical service arrival if the bystander only needed to travel one-way from the automated external defibrillator to the patient.
Effects of Monetary and Macroprudential Policies on Financial Conditions: Evidence from the United States

The Global Financial Crisis has reopened discussions on the role of the monetary policy in preserving financial stability. Determining whether monetary policy affects financial variables domestically -- especially compared to the effects of macroprudential policies -- and across borders, is crucial in this context. This paper looks into these issues using U.S. exogenous monetary policy shocks and macroprudential policy measures. Estimates indicate that monetary policy shocks have significant and persistent effects on financial conditions and can attenuate long-term financial instability. In contrast, the impact of macroprudential policy measures is generally more immediate but shorter-lasting. Also, while an exogenous increase in U.S. monetary policy rates tends to reduce credit and house prices in other countries -- with the effects varying with country-specific characteristics -- an increase driven by improved U.S. economic conditions tends to have the opposite effect. Finally, we do not find evidence of cross-border spillover effects associated with U.S. macroprudential policies.
Cryptic Chromosomal Abnormalities Identified in Children With Congenital Heart Disease

Congenital heart disease (CHD) is the most common type of birth defect, and the etiology of most cases is unknown. CHD often occurs in association with other birth malformations, and only in a minority are disease-causing chromosomal abnormalities identified. We hypothesized that children with CHD and additional birth malformations have cryptic chromosomal abnormalities that might be uncovered using recently developed DNA microarray-based methodologies. We recruited 20 children with diverse forms of CHD and additional birth defects who had no chromosomal abnormality identified by conventional cytogenetic testing. Using whole-genome array comparative genomic hybridization, we screened this population, along with a matched control population with isolated heart defects, for chromosomal copy number variations. We discovered disease-causing cryptic chromosomal abnormalities in five children with CHD and additional birth defects versus none with isolated CHD. The chromosomal abnormalities included three unbalanced translocations, one interstitial duplication, and one interstitial deletion. The genetic abnormalities were predominantly identified in children with CHD and a neurologic abnormality. Our results suggest that a significant percentage of children with CHD and neurologic abnormalities harbor subtle chromosomal abnormalities. We propose that children who meet these two criteria should receive more extensive genetic testing to detect potential cryptic chromosomal abnormalities.
Ventricular Arrhythmias: Risk Stratification and Approach to Therapy After the Cardiac Arrhythmia Suppression Trial (CAST)

The Cardiac Arrhythmia Suppression Trial (CAST) was designed to determine if suppression of asymptomatic or minimally symptomatic high grade ventricular arrhythmias in patients within two years after myocardial infarction (MI) would reduce the rate of death from arrhythmia. * As a result of CAST, the role of antiarrhythmic drugs in the treatment of various arrhythmias has undergone reevaluation. There are two major goals of antiarrhythmic therapy for patients with ventricular arrhythmias: to suppress symptoms and prevent sudden cardiac death. Evaluation of the risk for sudden cardiac death requires knowledge of the patient as well as arrhythmia present. In this regard, several factors other than the arrhythmia are taken into consideration, including the type and severity of heart disease and left ventricular dysfunction (Fig. 1).
Toward the Ghosting Phenomenon in a Stereo-Based Map With a Collaborative RGB-D Repair

Although 3-D reconstruction of dynamic road environment by moving cameras has been broadly applied in recognition and navigation systems, this task is still considered challenging, especially under circumstances with moving objects, where the reconstruction precision is strongly harassed by the ghosting problem. To address this issue, in this paper, we propose a novel approach for reconstructing 3-D maps of complete static scenes, based on a combination of an elaborately designed moving-object filtering mechanism and a map repairing and blank refilling procedure, where both plausible color and depth information from stereo image pairs are utilized. In this approach, first, we employ the planarity knowledge into the initial depth map based on the simple linear iterative cluster (SLIC) superpixel segmentation. The dynamic area in the image is determined under the supervision of odometry calculation. After wiping off moving objects, by collaboratively repairing color and depth information, the final 3-D map containing only static scene is obtained. The experimental results on extensive challenging real-world scenarios demonstrate the effectiveness and robustness of our approach.
High-Resolution Real-Time Underwater 3-D Acoustical Imaging Through Designing Ultralarge Ultrasparse Ultra-Wideband 2-D Arrays

Acoustical imaging systems are an important kind of instrumentation for underwater investigation. Currently, angular resolutions of most existing real-time underwater 3-D imaging systems are around 1°, which cannot meet the high-quality imaging requirement in a relatively far distance. Enhancing the angular resolution of a real-time 3-D imaging system needs enlarging the aperture size of its receiving 2-D array. However, the huge number of elements is not affordable for a traditional fully sampled uniform large 2-D array with half-wavelength interelement spacing to achieve a high angular resolution. This paper proposes the concept of ultralarge ultrasparse ultra-wideband (UUU) 2-D arrays for achieving the high angular resolution of underwater 3-D acoustical imaging systems. The design method of UUU 2-D arrays is demonstrated through the example of designing an annular 2-D array with only 100 elements. The capabilities of the designed annular UUU 2-D array are evaluated, showing that it can achieve a 0.1° angular resolution and a −32 dB maximum sidelobe level. The imaging simulations of complicated targets also demonstrate that the designed annular UUU 2-D array can satisfy the requirement of high-resolution underwater 3-D acoustical imaging. The element number of the designed annular UUU 2-D array is 4 orders of magnitude lower than that of a fully sampled uniform 2-D array, which provides a viable choice for developing high-resolution real-time underwater 3-D acoustical imaging systems.
Factors Affecting Information Technology Usage: A Meta-Analysis of the Empirical Literature

With an estimated investment of over 1 trillion dollars to date on information technology (IT) products and applications, one would hope that there exists a corresponding improvement in organizational performance and productivity. The level of IT usage has widely been accepted as an important indicator of IT success within organizations. This research synthesizes and validates the construct of IT usage using a meta-analysis. It accomplishes that by analyzing the empirical results of various studies over a period of time covering a broad scope of characteristics of both users and information systems (IS), and it examines the relation between these characteristics and the level of IT usage within organizations. In general, the results of this meta-analysis lead to the conclusion that there exists a strong and significant positive relation between the perception of ease of use and the perceived usefulness of an IT system to the actual amount of usage. Another factor that indicates a high level of IT usage is the organizational support of IT within an enterprise. Although the factors of education level, training level, and professional level were found to have a substantial effect on IT usage, the magnitude of these effects were lower than those of the perceptions of the user and organizational support. Managers and IT professionals may have a better chance of avoiding IT system ineffectiveness and even failure by paying attention to the results of this research, especially in view of the fact that it synthesized and validated the results of a significant number of empirical studies published in some of the best IS journals. Rarely do single research experiments provide definitive answers on which to base policy decisions.
Connecting Self-Efficacy and Nature of Science Shifts in Undergraduate Research Experiences

Undergraduate research can support students’ more central participation in physics. We present analysis of one way this participation may shift: changes in their beliefs about the Nature of Science coupled to changes in a sense of ability to contribute to authentic research. Students in the study worked with faculty and graduate student research mentors on research projects and also participated in a seminar where they learned about research and reflected on their experiences. In videotaped interviews, we asked students to describe their experiences in research. Students developed nuanced views about how the research process works coupled to shifts in their sense of confidence in ability to contribute to research, feeling like their contributions as novices mattered. PACS: 01.40. -d, 01.40. Fk, 01.30. Cc
Comparison of accuracy and safety of the SEVEN and the Navigator continuous glucose monitoring systems.

OBJECTIVE This study evaluated the accuracy and safety of two continuous glucose monitoring (CGM) systems, the SEVEN (DexCom, San Diego, CA) and the Navigator (Abbott Diabetes Care, Alameda, CA), with the YSI laboratory measurements of blood glucose (blood glucose meter manufactured by YSI, Yellow Springs, OH), when worn concurrently in adults with type 1 diabetes. DESIGN AND METHODS Fourteen subjects with type 1 diabetes, 33 +/- 6 (mean +/- SD) years old, were enrolled in this study. All subjects wore both sensors concurrently over three consecutive 5-day CGM sessions (15-day wear). On Days 5, 10, and 15, subjects participated in an 8-h in-clinic session where measurements from the CGM systems were collected and compared with YSI measurements every 15 min. At the end of Day 5 and 10 in-clinic sessions, the sensors were removed, and new sensors were inserted for the following CGM session despite the SEVEN system's recommended use for up to 7 days. RESULTS The mean absolute relative difference (ARD) for the two CGM devices versus YSI was not different: 16.8% and 16.1% for SEVEN and Navigator, respectively (P = 0.38). In the hypoglycemic region (YSI value <80 mg/dL), the mean ARD for SEVEN was lower than for Navigator (21.5% vs. 29.8%, respectively; P = 0.001). The data analyses were similar when compared with self-monitoring of blood glucose (SMBG) values. Thirteen additional Navigator replacement devices were issued compared to two for the SEVEN. A total of three versus 14 skin reactions were reported with the SEVEN and Navigator insertion area, respectively. CONCLUSIONS Glucose measurements with the SEVEN and Navigator were found to be similar compared with YSI and SMBG measurements, with the exception of the hypoglycemic range where the SEVEN performed better. However, the Navigator caused more skin area reactions.
Factors of Job-related Stress As Perceived by Middle School Principals in Virginia

FACTORS OF JOB-RELATED STRESS AS PERCEIVED BY MIDDLE SCHOOL PRINCIPALS IN VIRGINIA by Teresa Harper Snyder This study was conducted among middle school principals in Virginia to determine their perceptions of job-related stress factors. The entire population of middle school principals (grades 6,7,8) was selected to participate in the study. The Administrative Stress Index was used, to assess factors that cause principals stress on the job and to measure their stress levels. A demographic data form was used to collect data on the variables of age, gender, administrative experience, assistant principal support, student enrollment, adults supervised, percentage of students receiving free or reduced lunch, location of school, type of school, experience as a middle school principal, and educational attainment to determine if any of these variables correlated with the principals' stress as measured by the Administrative Stress Index. The Administrative Stress Index contained five subscales of seven questions each, which were used to indicate the perceptions of stress factors among the middle school principals in the study. The responses to the questionnaires were analyzed and the following statistics were computed from the data.percentage distribution, content analysis, multiple linear regression, and descriptive statistics.
Synthesis and Characterization of Pectin/PVP Hydrogel Membranes for Drug Delivery System

The purpose of the present study was to develop and design pectin and polyvinyl pyrrolidone (PVP) blended hydrogel membranes (PEVP), with different pectin: PVP ratios (1:0.2, 1:0.4, 1:0.6, 1:0.8 and 1:1 w/w), which were prepared by using a conventional solution casting technique. An attempt has been made to characterize the hydrogel membranes by various instrumental techniques like, FTIR (Fourier transform infrared) spectroscopy, X-ray diffraction (XRD), Differential scanning calorimetry (DSC), tensile strength test and scanning electron microscopy (SEM). The release patterns of the drug (salicylic acid) from the hydrogel membrane were done in three different release mediums (pH 1.4, pH 7.4 and distilled water) and samples were analyzed spectrophotometrically at 294 nm wavelength on a UV Vis spectrophotometer. MTT assay was done to ensure cytocompatibility of the pectin/PVP hydrogel membranes using B16 melanoma cells. FTIR spectroscopy indicated the presence of secondary amide (I) absorption bands. The XRD study shows decrease in crystallinity of the hydrogel membranes with increase in PVP ratio. DSC study shows an increase in Tg of pectin after blending with PVP. It was found that tensile strength increases with increasing PVP ratios in the hydrogel membranes. The prepared hydrogel membranes were found to be biocompatible with B16 melanoma cells.
The Value of Active Investing

We examine whether the value of active investment management can exceed its cost, and find that it can, by a substantial margin. We consider the 0.67% average cost estimate in French (2008), comparing it versus the expected value of a known active investment strategy. For a “passive” benchmark, we develop a 225 year index of monthly U.S. equity market returns, from July 1789 through June 2014. This timeframe encompasses the entire history of every U.S. exchange and includes all known periods of secondary market stock trading in the United States. We then estimate the long-run monthly returns of an active investment strategy based on an actual 11-year investment strategy. We present a new performance model extending the Treynor and Mazuy (1966) model and implement it to estimate monthly returns to the active strategy over the same 225 year period. We believe this experiment offers a good example of how the value of well-constructed active investment strategies can be worth substantially more than their cost.