Miracle-dz/UniFAR-FTUs huggingface dataset:
Distribution of immunogenic epitopes on the two major immunodominant proteins (rOmpA and rOmpB) of Rickettsia conorii among the other rickettsiae of the spotted fever group

Forty-four monoclonal antibodies were raised against strain Seven, the type strain of Rickettsia conorii. Of these 44 monoclonal antibodies, 13, 27, and 4 were demonstrated to be directed against the 116-kDa protein (rOmpA), the 124-kDa protein (rOmpB), and lipopolysaccharide-like antigen, respectively. The antiprotein monoclonal antibodies were found to be directed against 29 distinct epitopes, which were located on the two major immunodominant proteins discussed above. Further analysis showed that strain-specific epitopes were located on the rOmpA protein and species- and subgroup-specific epitopes were located on the rOmpB protein. R. conorii Manuel, Indian tick typhus rickettsia, and Kenya tick typhus rickettsia also possessed all 29 epitopes, whereas the other rickettsiae of the spotted fever group (SFG) expressed between 3 and 25 epitopes, with the exception of Rickettsia helvetica, R. akari, and R. australis which did not possess any epitopes. Additional analyses by Western immunoblotting confirmed that the epitopes shared among the SFG rickettsiae were located on the same two high-molecular-mass proteins as on R. conorii. However, although epitopes on the R. conorii rOmpB protein were expressed on the rOmpB proteins of most other SFG rickettsiae, some were found on the rOmpA proteins of R. aeschlimannii, R. rickettsii, and R. rhipicephali. Both proteins possessing the common epitopes were found to have different sizes in the SFG rickettsial species. The different distributions of common epitopes in the SFG rickettsiae were also used to build a taxonomic dendrogram, which demonstrated that all the R. conorii strains formed a relatively independent cluster within the SFG rickettsiae and was generally consistent with previously proposed taxonomies.
Study of Behavioural Traits of Grape Exporters in Maharashtra

Many farmers from Maharashtra have become successful grape exporter by associating themselves to organizations like Mahagrapes. Study was conducted with ninety grape growers from Nashik, Sangli and Pune district of Maharashtra, who were members of cooperatives associated with the Mahagrapes organization. While studying socioeconomic and behavioral traits of these farmers it was observed 56 per cent members belonged to medium age category. In case of education 34.4 per cent members had completed their graduation and average annual income obtained was Rs. 13.32 lakh. About 15.5 per cent of total members were small and marginal, while 50 per cent belonged to semi medium (2.1-4 ha) land holding category. Productivity of grapes at members’ field was 11.78 tons per acre. Members showed higher level of achievement motivation and self confidence. Productivity of grapes was positively and significantly correlated with the annual income, material possession, achievement motivation and self confidence of the member farmers.
Practice guidelines on the diagnosis, surveillance, and therapy of Barrett's esophagus

These guidelines are developed under the auspices of the American College of Gastroenterology (ACG) and its Practice Parameters Committee and approved by the Board of Trustees. They have been intensely reviewed and revised by the Committee, other experts in the field, physicians who will use them, and specialists in the science of decision analysis. When approved by the ACG, they are submitted to the other major gastrointestinal societies (American Gastroenterolgical Association and the American Society for Gastrointestinal Endoscopy) for their review and approval. To develop the guidelines, the world literature is searched, then all appropriate studies are reviewed and evaluated by the authors. In the literature review, evidence is evaluated along a hierarchy with randomized, controlled trials given the greatest weight. No randomized controlled trials are available to address the issues in this guideline. Recommendations are based on large observational series and expert opinion. Abstracts presented at national and international meetings are used only in special circumstances in which unique data from ongoing trials were presented. These guidelines are intended to be applicable to all physicians who address the subject without regard to specialty training or interests and are intended to indicate the preferable, but not the only acceptable, approach to this problem. Given the wide range of specifics in any health care problem, the physician must always choose the course best suited to the individual patient and the variables in existence at the moment of decision.
Anti-LAMP-2 autoantibodies in ANCA-associated pauci-immune glomerulonephritis.

The association between anti–lysosome-associated membrane protein 2 (LAMP-2) autoantibodies and vasculitis is not new; it dates back to work by Kain et al. [1][1] in 1995 that identified LAMP-2 as a target of antineutrophil cytoplasmic antibodies (ANCA) in 14 of 16 patients with a pauci-immune
Association of Developmental Venous Anomalies with Demyelinating Lesions in Patients with Multiple Sclerosis

SUMMARY: We present 5 cases of demyelination in patients diagnosed with multiple sclerosis that are closely associated with a developmental venous anomaly. Although the presence of a central vein is a known phenomenon with multiple sclerosis plaques, demyelination occurring around developmental venous anomalies is an underreported phenomenon. Tumefactive demyelination can cause a diagnostic dilemma because of its overlapping imaging findings with central nervous system neoplasm. The relationship of a tumefactive plaque with a central vein can be diagnostically useful, and we suggest that if such a lesion is closely associated with a developmental venous anomaly, an inflammatory or demyelinating etiology should be a leading consideration.
Modified formalin and methanol fixation methods for molecular biological and morphological analyses

Several simplified fixation methods were examined to determine their suitability for both molecular biological analyses and morphological study. Fixation with 10% v/v formalin alone at 4°C and containing 5 mmol/L ethylenediamine‐N, N, N', N'‐tetraacetic acld (EDTA) at room temperature preserved significantly more high‐molecular‐weight DNA than 10% v/v formalin fixation at room temperature. The morphological differences between tissues fixed using these modified formalin fixation methods and conventional 10% v/v formalin fixation were negligible. Of the dehydration fixatives tested, 100% methanol did not cause regional differences due to artificial tissue shrinkage and the morphology of sections prepared by methanol fixation was preserved consistently better than that of acetone‐ or ethanol‐fixed sections. All three dehydration fixatives preserved relatively higher‐molecular‐weight DNA and RNA, compared with formalin. Cold formalin, formalin containing EDTA at room temperature and 100% methanol are recommended as standard and additional fixatives routine clinic pathological laboratory use.
Impact of Customer Perceived Value and Customers Perception of Public Relation on Customer Loyalty with Moderating Role of Brand Image

Purpose/Significance: The purpose of this study was to investigate the relationship between customer perceived value and customer’s perception of public relation on customer loyalty with moderating role of brand image. Research was conducted on banking sector of Pakistan. Design/methodology/approach: Data collected in a survey that yielded 930 respondents. Questionnaire was adopted from research work of Zeithaml, Berry, and Parasuraman (1996) and Park, Jaworski, and Maclnnis (1986). Deductive -Positive - Quantitative Approach was used for the analysis. A theoretical framework was proposed to suggest links among variables. Multiple regression and Moderating regression were used to examine the hypothesized relationship. Findings: It was found that Customer Perceived value, Customer’s Perception of Public relation brought 94.0% change on customer loyalty. Study concluded that there was a strong positive significant relationship between proposed variables. To check the moderation of brand image researcher took the interaction of all independent variables with brand image. Results prevailed that there was significant qasi moderation exist. Research limitations/implication: Further research is indicated, to identify effects of these variables on other services provider companies of excluding Pakistani banking sector. Banking sector in Pakistan should pay more attention on Customer’s Perception of Public relation and Customer Perceived Value, in order to enhance the customer loyalty. Originality/value: This study is the first study that tests the western model on south eastern countries like Pakistan. In addition to that there is no research work found that reflects on customer perceived value and Customer’s perception of public relation with moderating effect of brand image especially on banking sector of Pakistan. This document will help managers to adopt appropriate strategies that will lead banking sector towards prosperity.
Principles of urban structure in social spaces of shopping malls

Today it is hard to imagine a large modern city without a shopping mall. Actually mall emerged as a kind of city center for periphery residents. However, in today’s fast paced life the concept of “everything under one roof” has become an integral part of the urban structure. Mall makes it possible to meet not one but a number of needs at once. The fact that mall is analogous to city centre is confirmed not only by their functional content similarity, but also by structure. Like urban web is anchored at nodes of human activity, “shopping mall web” is anchored on nodes of retail and entertainment spaces. Like urban structures have a hierarchy of connections (from footpaths to roads), shopping mall structure has a hierarchy of social spaces (from side malls to the centre court). Despite this similarity, the socialization and communication problems in shopping malls remain unsolved. In this study the comparative analysis of urban and shopping mall structures was performed. We defined the key urban structure principles suitable for effective formation of social and public spaces of malls.
Assessing the role of interbank network structure in business and financial cycle analysis

We develop a DSGE model incorporating a banking sector comprising 4 banks connected in a stylised network representing their interbank exposures. The micro-founded framework allows inter alia for endogenous bank defaults and bank capital requirements. In addition, we introduce a central bank who intervenes directly in the interbank market through liquidity injections. Model dynamics are driven by standard productivity as well as banking sector shocks. In our simulations, we incorporate four different interbank network structures: Complete, cyclical and two variations of the coreperiphery topology. Comparison of interbank market dynamics under the different topologies reveals a strong stabilising role played by the complete network while the remaining structures show a non-negligible shock propagation mechanism. Finally, we show that central bank interventions can counteract negative banking shocks with the effect depending again on the network structure.
Predicting human mobility with activity changes

Human mobility patterns can provide valuable information in understanding the impact of human behavioral regularities in urban systems, usually with a specific focus on traffic prediction, public health or urban planning. While existing studies on human movement have placed huge emphasis on spatial location to predict where people go next, the time dimension component is usually being treated with oversimplification or even being neglected. Time dimension is crucial to understanding and detecting human activity changes, which play a negative role in prediction and thus may affect the predictive accuracy. This study aims to predict human movement from a spatio-temporal perspective by taking into account the impact of activity changes. We analyze and define changes of human activity and propose an algorithm to detect such changes, based on which a Markov chain model is used to predict human movement. The Microsoft GeoLife dataset is used to test our methodology, and the data of two selected users is used to evaluate the performance of the prediction. We compare the predictive accuracy (R2) derived from the data with and without implementing the activity change detection. The results show that the R2 is improved from 0.295 to 0.762 for the user with obvious activity changes and from 0.965 to 0.971 for the user without obvious activity changes. The method proposed by this study improves the accuracy in analyzing and predicting human movement and lays the foundation for related urban studies.
Heavy Metal Concentrations in Ten Species of Fishes Caught in Sinop Coastal Waters of the Black Sea, Turkey

In the present study, the heavy metal concentrations (zinc, copper, cadmium and lead) have been measured in dorsal muscle tissue of ten species (Trachurus mediterraneus, Sprattus sprattus sprattus, Mullus surmelatus, Sarda sarda, Mugil cephalus, Scorpaena porcus, Sparus aurata, Umbrina cirrosa, Spicara maena and Solea solea) from Sinop coast of the Black Sea, Turkey during fish season in 2010. Significant differences in metal concentrations were found between the species (P<0.05). In general, it was found that the levels of heavy metals studied were lower than the maximum permissible limit of the food regulations of the Ministry of Agriculture, Fisheries and Food (MAFF), the Turkish Food Codex and Commission Regulation (EC). Cd showed the lowest concentrations in all fish samples followed by Pb. The results of the present study were compared with the other studies and discussed.
Substantial native American female contribution to the population of Tacuarembó, Uruguay, reveals past episodes of sex‐biased gene flow

For many years it has been assumed that the population of Uruguay is almost exclusively European‐derived and that the biological contribution of the native population as well as of individuals of African descent is negligible. Several recent studies based on a variety of genetic markers, mostly morphological and serological markers, have produced quite a different picture of the constitution of the Uruguayan population. The Native American contribution varies from 1–20%, while the African contribution ranges from 7–15%, in different regions of the country. In the present study we examine the way the admixture process took place in Uruguay by analyzing the ancestry of maternal lineages in a sample from the northern city of Tacuarembó. To accomplish this goal we typed mitochondrial DNA (mtDNA) markers of Native American, African, and European origin and estimated the proportions of each parental group in the admixed population. We found that 62% of all mtDNA haplogroups were of Native American descent, a surprising figure considering the “European roots” of the country. Consequently, this result assimilates Uruguay to the rest of Latin American populations where sex‐biased gene flow between European men and Native American women has been the rule. We further analyzed the distribution of the four major founding mitochondrial lineages in Tacuarembó and compared it to other South American populations. We discuss our findings in the light of historical records and assess the need for additional genetic studies. Am. J. Hum. Biol. 16:289–297, 2004. © 2004 Wiley‐Liss, Inc.
Coordinating online health communities for cognitive and affective value creation

Purpose – The purpose of this paper is to develop a framework investigating patterns of online health communities. In particular, the study draws on coordination theory to identify four community configurations. Their distinct features determine communities’ capacity to internalize and externalize knowledge, which ultimately determines their value creation in a service context. Design/methodology/approach – The authors apply qualitative and quantitative techniques to detect similarities and differences in a sample of 50 online health communities. A categorical principal component analysis combined with cluster analysis reveals four distinct community configurations. Findings – The analysis reveals differences in the degrees of cognitive and affective value creation, the types of community activities, the involved patients, professionals, and other stakeholders; and the levels of data disclosure by community members. Four community configurations emerge: basic information provider, advanced patient knowled.
Shared Language, shared Knowledge? Investigating barriers and facilitators to knowledge transfer in a common language context: the case of European Multinational Corporations

i ACKNOWLEDGEMENTS . ii LIST OF ABBREVIATIONS . iii 1. INTRODUCTION . 1 1.1 Background . 1 1.2 Problem Discussion . 2 1.3 Research Question and Study Focus . 4 1.4 Chapter Outline . 5 2. LITERATURE REVIEW . 6 2.1 Shared Language . 6 2.1.1 Shared language and communication . 7 2.2 Knowledge . 8 2.2.1 Knowledge and information . 8 2.2.2 Tacit and explicit knowledge . 9 2.3 Knowledge Transfer . 10 2.3.1 Definition of knowledge transfer and knowledge sharing . 10 2.3.2 Modes of knowledge creation and transfer . 10 2.3.3 International knowledge transfer process . 11 2.4 Barriers and Facilitators to Knowledge Transfer . 12 2.4.1 Social relations . 13 2.4.2 Technology . 15 2.5 Conceptual Framework . 17 3. METHODOLOGY . 19 3.1 Research Approach . 19 3.2 Research Units and Respondents . 20 3.3 Data Collection Method . 20 3.4 Interview Protocol and Process . 22 3.5 Data Analysis . 24 3.5. 1 Corpus linguistics: a way of managing textual data in international business studies . 24 3.5. 2 Concordance program analysis . 26 4. EMPIRICAL FINDINGS . 28 4.1 Shared Language . 31 4.2 Company Culture and Leadership . 33 4.2.1 Company culture . 36 4.2.2 Leadership . 39 4.3 Communication Process and Tools . 41 4.3.1 Communication and culture . 43 4.3.2 Meetings . 44 4.3.3 Software tools and platforms . 46
Hypertensive Urgency Associated With Xenadrine EFX Use

Several supplements and herbal products have been shown to increase catecholamines and subsequently mean arterial pressure and systemic vascular resistance. Since ephedra-containing products have been removed from the market, manufacturers of weight loss herbal supplements must produce ephedra-free formulations. Xenadrine EFX is an ephedra-free weight loss product containing a mixture of caffeine, guarana, and bitter orange (standardized to synephrine). Synephrine has been shown in animals and humans to increase systemic vascular resistance and mean arterial pressure. We present a case of a patient who took Xendarine EFX for 2 weeks prior to her presentation to an emergency department with headaches and hypertensive urgency (blood pressure [BP] 234/130 mm Hg). Her BP was controlled after discontinuation of Xenadrine and initiation a nitroprusside drip and oral clonidine. A Naranjo probability score of 6 indicates the adverse drug reaction was probable. Clinicians should be aware of potential cardiovascular changes in patients on Xenadrine EFX or other synephrine-containing products.
Creating Enduring Customer Value

One of the most important tasks in marketing is to create and communicate value to customers to drive their satisfaction, loyalty, and profitability. In this study, the authors assume that customer value is a dual concept. First, in order to be successful, firms (and the marketing function) have to create perceived value for customers. Toward that end, marketers have to measure customer perceived value and have to provide customer perceptions of value through marketing-mix elements. Second, customers in return give value through multiple forms of engagement (customer lifetime value, in the widest sense) for the organization. Therefore, marketers need to measure and manage this value of the customer(s) to the firm and have to incorporate this aspect into real-time marketing decisions. The authors integrate and synthesize existing findings, show the best practices of implementation, and highlight future research avenues.
Improved adaptive beamforming using a hybrid LMS/SMI approach

This paper proposes a hybrid algorithm for improved adaptive beamforming by combining the attributes of LMS and SMI algorithms. The proposed algorithm uses the LMS algorithm, which simple to implement and not computationally intensive, with SMI initialization in order to ensure fast convergence. Numerical results are presented to verify the improved convergence, accuracy, and computational efficiency of the proposed hybrid LMS/SMI algorithm.
Inclinometric measurement of kyphotic curvature: Description and clinimetric properties

ABSTRACT Background: Hyperkyphosis is associated with physical impairments, activity limitations, and reduced quality of life. Therefore, a simple, reliable, responsive, and valid clinical measure of dorsal kyphosis would be valuable to clinicians. Objective: To describe a novel procedure for measuring kyphotic curvature—the inclinometric kyphosis measure (IKM)—and provide an estimation of reliability, responsiveness, and validity. Methods: During 2 sessions spaced days apart, we used a bubble inclinometer to measure dorsal kyphosis in 68 patients receiving outpatient physical therapy. We also documented occiput-to-wall status and tragus-to-wall distance. Results: Intra-rater reliability of the IKM was supported by intra-class correlation coefficients (ICC3,1) of 0.94 and 0.91 for relaxed and cued conditions, respectively. Responsiveness, as indicated by minimal detectable change, was 8.0 and 10.0 degrees under relaxed and cued conditions, respectively. Validity was supported by significant correlations between the IKM and tragus-to-wall and by differences in the IKM between: 1) relaxed and cued conditions; 2) patients who could and could not touch occiput to the wall; and 3) patients who were older versus younger than 50 years of age. Conclusions: The IKM is a simple, reliable, responsive, and valid method for assessing posture in patients with musculoskeletal conditions.
Influence of Entrepreneurial Marketing toward Innovation and Its Impact on Business Performance: A Survey on Small Industries of Wearing Apparel in West Java, Indonesia

The purpose of this study is to examine the effect of entrepreneurial marketing to innovation and its impact on marketing performance and financial performance of wearing apparel small industries in West Java, Indonesia. Total sample was 200 small industries, survey method is used and data analysis technique used in this research was a variance-base partial least squares SEM (Structural Equation Modeling) technique with WarpPLS 5.0. The results suggest that entrepreneurial marketing have an effect on innovation, marketing performance and financial performance. Innovation has an influence to marketing performance and financial performance. Nevertheless, this research study of wearing apparel small industries in West Java, Indonesia, while the industry category varies, i.e knitwear; textile and leather. Future research is expected to take a more specific analysis unit by separating different categories, in order to obtain more specific research.
Amplitude relations in heterotic string theory and Einstein -

We present all-multiplicity evidence that the tree-level S-matrix of gluons and gravitons in heterotic string theory can be reduced to color-ordered single-trace amplitudes of the gauge multiplet. Explicit amplitude relations are derived for up to three gravitons, up to two color traces and an arbitrary number of gluons in each case. The results are valid to all orders in the inverse string tension α and generalize to the ten-dimensional superamplitudes which preserve 16 supercharges. Their field-theory limit results in an alternative proof of the recently discovered relations between Einstein-Yang-Mills amplitudes and those of pure Yang-Mills theory. Similarities and differences between the integrands of the Cachazo-HeYuan formulae and the heterotic string are investigated.