Miracle-dz/UniFAR-FTUs huggingface dataset:
Rhabdomyolysis After Performing Blood Flow Restriction Training: A Case Report

Abstract Tabata, S, Suzuki, Y, Azuma, K, and Matsumoto, H. Rhabdomyolysis after performing blood flow restriction training: a case report. J Strength Cond Res 30(7): 2064–2068, 2016—Rhabdomyolysis is a serious and potentially life-threatening condition related to resistance training. Despite numerous reports of low-intensity blood flow restriction (BFR) training inducing muscle hypertrophy and increasing strength, few reports of rhabdomyolysis related to BFR training have been published. Here, we report a 30-year-old obese Japanese man admitted to our hospital the day after his first BFR training session with complaints of severe muscle pain in his upper and lower extremities, high fever, and pharyngeal pain. He was diagnosed with acute rhabdomyolysis based on a serum creatine phosphokinase level of 56,475 U·L−1 and a urine myoglobin level of >3,000 ng·ml−1, and with acute tonsillitis based on a white blood cell count of 17,390 and C-reactive protein level of 10.43 mg·dl−1. A number of factors are suspected to be related to the onset and exacerbation of rhabdomyolysis, including excessive muscular training with BFR, bacterial infection, and medication. After 10 days of hospitalization with intravenous fluids and antibacterial drugs, he recovered without complications. This case indicates that BFR training should be conducted with careful consideration of the physical condition and strength of the individual to prevent serious complications, such as rhabdomyolysis.
The frequency and nature of ‘cloud–cloud collisions’ in galaxies

We investigate cloud–cloud collisions and giant molecular cloud evolution in hydrodynamic simulations of isolated galaxies. The simulations include heating and cooling of the interstellar medium (ISM), self-gravity and stellar feedback. Over time-scales <5 Myr most clouds undergo no change, and mergers and splits are found to be typically two-body processes, but evolution over longer time-scales is more complex and involves a greater fraction of intercloud material. We find that mergers or collisions occur every 8–10 Myr (1/15th of an orbit) in a simulation with spiral arms, and once every 28 Myr (1/5th of an orbit) with no imposed spiral arms. Both figures are higher than expected from analytic estimates, as clouds are not uniformly distributed in the galaxy. Thus, clouds can be expected to undergo between zero and a few collisions over their lifetime. We present specific examples of cloud–cloud interactions in our results, including synthetic CO maps. We would expect cloud–cloud interactions to be observable, but find they appear to have little or no impact on the ISM. Due to a combination of the clouds’ typical geometries, and moderate velocity dispersions, cloud–cloud interactions often better resemble a smaller cloud nudging a larger cloud. Our findings are consistent with the view that spiral arms make little difference to overall star formation rates in galaxies, and we see no evidence that collisions likely produce massive clusters. However, to confirm the outcome of such massive cloud collisions we ideally need higher resolution simulations.
Effect of Oral Levamisole Supplementation to Hepatitis B Vaccination on the Rate of Immune Response in Chronic Hemodialysis Patients

Accessible online at: www.karger. com/journals/nef Dear Sir, Patients with chronic renal failure on hemodialysis (HD) carry an increased risk of hepatitis B virus infection due to defective immune response, resulting from T cell effector dysfunction [1]. When the vaccine was first introduced in the early 1980s, it was hoped that hepatitis B virus would be completely eliminated from the renal failure population. However, the results of most of the vaccination programs have been disappointing. Due to a specific defect, only 50– 60% of the patients form significant and protective antibodies [2]. Specific antibody formation to infectious agents and vaccines is also deficient in these patients. Thus, standard vaccination protocols were enhanced in order to improve protection. Current recommendations include vaccination with twice the standard dose of vaccine by four intramusculer injections at months 0, 1, 6, and 9. Despite these measures, the proportion of patients protected by vaccination could not be increased. Interleukin 2, gamma interferon, thymopentin, zinc, and colony-stimulating factor were added to standard vaccinations in order to increase the immune response [3–7]. These were, however, experimental protocols and cannot be recommended as routine procedures. We have, therefore, decided to investigate the effects of levamisole, a nonspecific immune modulator, on the immune response following vaccination. Sixty patients (34 males, 26 females), ranging in age from 18 to 63 (mean B SD 41.4 B 2.4) years were included in the study. Patients were on HD (three times per week) for 11.8 B 1.1 months and were HBsAg, anti-HBs, anti-HBc, anti-HBe, and HBeAg negative with no prior vaccination. Four randomized patient groups were formed together with 15 healthy controls (9 males and 6 females with a mean age of 37.4 B 1.7 years). The patients received intramuscular recombinant DNA-B hepatitis vaccine (Engerix B; 20 Ìg) into the deltoid muscle at 0, 1, 6, and 9 months. Group 1 received a single dose, group 2 had a double dose, group 3 had a single dose plus 120 mg oral levamisole after HD, and group 4 had a double-dose vaccine plus 120 mg oral levamisole after HD. HBsAg and anti-HBs were evaluated by means of a microparticle enzyme immunoassay technique using Abbott-Axoym systems. Cases with an antiHBs level 110 mIU/ml were considered as ‘antibody positive’. These tests were performed at 3 and 10 months. Data are given as mean B SD. The results were compared with the paired chiTable 1. Number of patients in each group responding to hepatitis B vaccination
Cross sections for production of the 15.10-MeV and other astrophysically significant gamma-ray lines through excitation and spallation of 12C and 16O with protons.

The ratio of the flux of 15.10-MeV gamma rays to the flux of 4.438-MeV gamma rays resulting from excitation of the corresponding states in /sup 12/C is a sensitive measure of the spectrum of the exciting particles produced in solar flares and other cosmic sources. These gamma rays are produced predominantly by interactions with /sup 12/C and /sup 16/O, both of which are relatively abundant in the solar photosphere. Gamma-ray production cross sections for proton interactions have been reported previously for all important channels except for the production of 15.10-MeV gamma rays from /sup 16/O. The first reported measurement of the 15.10-MeV gamma-ray production cross section from p+ /sup 16/O is presented here. A cyclotron was employed to produce 40-, 65-, and 85-MeV protons which interacted with CH/sub 2/ and BeO targets. The resultant gamma-ray spectra were measured with a high-purity germanium semiconductor detector at 70, 90, 110, 125, and 140 deg relative to the direction of the incident beam for each proton energy. Other gamma-ray lines resulting from direct excitation and spallation reactions with /sup 12/C and /sup 16/O were observed as well, and their gamma-ray production cross sections, several of which have not been reported previously, are presented.more » The results are compared with previously reported measurements, as available. « less
Social deficits in autism: an operational approach using the Vineland Adaptive Behavior Scales.

Abstract Although social factors are commonly viewed as an important defining characteristics of the autistic syndrome, earlier research studies have not systematically evaluated social dysfunction in autistic individuals. In this study, the Vineland Adaptive Behavior Scales were used to assess adaptive behavior in a group of autistic and a group of nonautistic, developmentally disabled, individuals. As compared to nonautistic subjects, the autistic group exhibited significantly greater deficits in adaptive social behaviors. The result suggests the utility of a well-standardized, normative assessment instrument for documenting autistic social dysfunction.
Relevance drives attention: Attentional bias for gain- and loss-related stimuli is driven by delayed disengagement

Attentional bias to gain- and loss-related stimuli was investigated in a dot-probe task. We used coloured stimuli that had acquired their valence during the experiment by signalling the chance to either win or lose points in a game task. Replicating previous findings with the additional singleton paradigm, we found attentional bias effects for both gain- and loss-related colours. The effects were due to delayed disengagement from valent stimuli, especially if they were positive, and could not be explained by nonattentional processes like behavioural freezing. Our findings suggest that stimuli signalling opportunities and dangers hold attention, supporting a general motivational relevance principle of the orienting of attention.
Expression of genes and proteins of the pax‐six‐eya‐dach network in the metamorphic sea urchin: Insights into development of the enigmatic echinoderm body plan and sensory structures

Background: Photoreception‐associated genes of the Pax‐Six‐Eya‐Dach network (PSEDN) are deployed for many roles in addition to photoreception development. In this first study of PSEDN genes during development of the pentameral body in sea urchins, we investigated their spatial expression in Heliocidaris erythrogramma. Results: Expression of PSEDN genes in the hydrocoele of early (Dach, Eya, Six1/2) and/or late (Pax6, Six3/6) larvae, and the five hydrocoele lobes, the first morphological expression of pentamery, supports a role in body plan development. Pax6, Six1/2, and Six3/6 were localized to the primary and/or secondary podia and putative sensory/neuronal cells. Six1/2 and Six3/6 were expressed in the neuropil region in the terminal disc of the podia. Dach was localized to spines. Sequential up‐regulation of gene expression as new podia and spines formed was evident. Rhabdomeric opsin and pax6 protein were localized to cells in the primary podia and spines. Conclusions: Our results support roles for PSEDN genes in development of the pentameral body plan, contributing to our understanding of how the most unusual body plan in the Bilateria may have evolved. Development of sensory cells within the Pax‐Six expression field is consistent with the role of these genes in sensory cell development in diverse species. Developmental Dynamics 247:239–249, 2018. © 2017 Wiley Periodicals, Inc.
Does the antenatal detection of fetal growth restriction (FGR) have a prognostic value for mortality and short-term morbidity for very preterm infants? Results from the MOSAIC cohort

Abstract Objective: We investigated the impact of antenatal diagnosis of fetal growth restriction (FGR) on the risks of mortality and morbidity for very preterm infants given actual birthweight percentiles. Methods: Data on 4608 live born infants 24–31 weeks of gestational age (GA) in 10 European regions in 2003 were used to compare in-hospital mortality, bronchopulmonary dysplasia (BPD) and severe neurological morbidity by birthweight percentiles and antenatal diagnosis of FGR. Other covariates were GA, sex, multiplicity, maternal complications, antenatal corticosteroids, birth in a level III center and region. Results: Sixteen percent (n = 728) of all infants and 72%, 30% and 6%, respectively, of those with birthweight percentiles <10th, 10th–24th and ≥25th had an antenatal diagnosis of FGR. After adjustment for clinical factors, antenatal diagnosis of FGR was not associated with mortality for infants with a birthweight ≥10th percentile (OR [95% CI]: 0.9 [0.5–1.9] and 1.0 [0.6–1.8] for birthweights between the 10th–24th percentile and ≥25th percentile, respectively), but infants with a birthweight <10th percentile had higher mortality (OR [95% CI]: 2.4 [1.0–5.8]). No association was observed at any birthweight percentile with BPD or severe neurological morbidity. Conclusion: Antenatal diagnosis of FGR did not influence risks of mortality or morbidity when birthweight was ≥10th percentile; however, mortality risk was higher in antenatally detected infants with birthweight below the <10th percentile.
Association among Bad Breath, Body Mass Index, and Alcohol Intake

Bad breath is a common condition, difficult to assess in the general population. In the present study, we tested the hypothesis that a self-administered questionnaire can help identify factors associated with greater risk of oral malodor. Persons (n = 88) undergoing routine medical check-ups completed a questionnaire including 38 questions on general and oral health, dietary habits, and their own oral malodor levels. Oral malodor assessments included odor judge scores, volatile sulfide levels (via a Halimeter®, Interscan Corp.), and salivary β-galactosidase. Among the questionnaire results, 9 responses were significantly associated with odor judge scores (p < 0.05, unpaired t test), including questions on alcohol intake and body mass index (BMI). Predictions of odor judge scores based on these 9 questions (linear multiple regression analysis) yielded R = 0.601; when introduced together with Halimeter® and β-galactosidase scores, the correlation rose to R = 0.843. The results suggest that alcohol intake and BMI may be factors that help predict oral malodor.
Genomic DNA Amplification from a Single Bacterium

ABSTRACT Genomic DNA was amplified about 5 billion-fold from single, flow-sorted bacterial cells by the multiple displacement amplification (MDA) reaction, using φ 29 DNA polymerase. A 662-bp segment of the 16S rRNA gene could be accurately sequenced from the amplified DNA. MDA methods enable new strategies for studying nonculturable microorganisms.
Splitting Capacity Characterization of Bamboo Culms

The history of engineering knowledge with regards to bamboo is surprisingly recent, with the major work on bamboo having been completed by Janssen (1981) and Acre (1993) of the University of Eindhoven, The Netherlands. In their research, both noted that splitting is the dominant limit state in structural applications, which agrees with the author's experience (during our May 2008 visit to India) and that of other researchers. It is because of this dominant limit state that this research focused on the development of an appropriate method of characterizing the splitting strength of bamboo culms. This document focuses on developing and calibrating an appropriate (but simple to conduct) test method for assessing the splitting capacity of full culms. The proposed split-pin fracture test is founded on a fundamental fracture mechanics approach. This method, while simple to conduct, can account, in a consistent manner, for the high degree of variability present in bamboo geometric and material properties. In order to demonstrate the validity of the proposed test method, a series of tests were performed on a sample of Bambusa Stenostachya (Tre Gai) bamboo. In addition to the proposed fracture test, shear and compression tests were performed in accordance with existing ISO standards (ISO 2004b). Of the three test types performed, the compression test had the lowest variability, the shear test had the highest, and the proposed fracture tests had a variability that fell between the two. Thus the fracture test demonstrated that it yields reliable results.Utilizing the values obtained from both this series of tests as well as those carried out by other institutions, a comparison of common design values was made between Tre Gai and the select-structural grade of two commonly encountered woods, Douglas Fir and Southern Pine. While the design values for bamboo obtained from different institutions varied considerably, Tre Gai generally exhibited performance superior to that of the two timber species referenced. It can be concluded that Tre Gai, when grown, harvested, and preserved correctly, is a competitive, or in some cases, a superior alternative to wood.
Effects of Smokefree Class Competition 1 year after the end of intervention: a cluster randomised controlled trial

Background The Smokefree Class Competition, a school-based smoking prevention intervention, is widely disseminated in Europe. Participating classes commit themselves to be smoke-free and self-monitor their smoking status. Classes that remain smoke-free for 6 months can win prizes. Effects of the intervention on current smoking, initiation and progression of smoking were investigated. Methods Cluster randomised controlled trial. 84 schools (208 classes with 3490 students; mean age 12.6 years, 50.4% female) in Saxony-Anhalt, Germany, were randomly assigned to intervention or control condition. A baseline survey was conducted before the implementation of the programme, while post-test and follow-up surveys were carried out 7 (immediately after the end of the competition), 12 and 19 months after baseline. Effects of participation in the programme on current and lifetime smoking were analysed by multilevel models controlling for confounding variables. Results Intervention students smoking occasionally at baseline smoked less frequently than students taking not part in the intervention at 7 and 12 months after baseline. Persistent beneficial programme effects were also found for lifetime smoking: intervention students were less likely to progress from experimental to established use. Conclusion Data suggest that Smokefree Class Competition reduces the probability of progressing from occasional and experimental stages of smoking to more established forms of use. Clinical trials registration number Trial registration ISRCTN27091233 in Current Control Trial Register.
Granulomatous gastritis: a morphological and diagnostic approach

The final diagnosis of granulomatous gastritis is based on morphological findings and clinical and laboratory data. Detailed analysis of the morphological features of the granulomas together with associated mucosal changes could generate more information on aetiology and pathogenesis. Biopsies from 71 patients diagnosed as having granulomatous gastritis were reviewed. Thirty‐seven of these patients (52%) had Crohn's disease. In 18 patients (25%) an isolated granulomatous gastritis was diagnosed. In seven patients (10%) the final diagnosis was a foreign body reaction. Of the remaining cases, four (7%) corresponded to tumour‐associated granulomas and one case each of sarcoidosis (1%), Whipple's disease (1%) and vasculitis‐associated disease (1%). Two cases (3%) were unclassifiable. The granulomas were mainly found in the antrum (64% antrum only, 11% antrum and corpus, 6% transitional mucosa corpus‐antrum). Granulomas were usually small. This was particularly true for those found in patients with Crohn's disease. Multiple granulomas were observed in the sarcoidosis, the Whipple's disease and vasculitis‐associated cases. A pattern of chronic gastritis with atrophy was present in 95% of the biopsies (68/71 patients). Helicobacter pylori was detected in 92% of the biopsies (64/71 patients).
Joint load balancing and interference coordination can double heterogeneous network capacity

In a heterogeneous network (HetNet) obtained by overlaying low-power picocells on a conventional macrocell network, two important problems must be addressed in order to obtain significant downlink capacity gains. These are inter-cell load balancing, i.e., determining which cell must serve each user so as to utilize all cells effectively, and inter-cell interference coordination, i.e., determining when and for how long must each macrocell be silenced so as to mitigate interference caused to nearby picocell users. We formulate a centralized optimization framework for these coupled problems, and propose a simple solution to them based on convex relaxation and two applications of the Frank-Wolfe algorithm. Simulation results show that the proposed solution has near-optimal performance in a canonical “hotspot” network model, and can double both the 50th percentile and 5th percentile user rates, when compared to a baseline HetNet with no load balancing and no interference coordination. Further, both interference coordination and load balancing are necessary; each by itself yields much lower gains.
Expression of minute virus of mice structural proteins in murine cell lines transformed by bovine papillomavirus-minute virus of mice plasmid chimera

Recombinant plasmids containing the genomes of both bovine papillomavirus type I and minute virus of mice (MVM) were constructed and used to transform mouse C127 cells. Transformed lines that express MVM gene products with high efficiency were isolated and characterized. These transformants synthesize large amounts of MVM structural polypeptides and spontaneously assemble them into empty virion particles that are released into the culture medium. These lines were, however, genetically unstable; they slowly generated subpopulations that failed to express MVM-specific proteins, and they possessed episomal DNA in which both MVM and bovine papillomavirus sequences were deleted or rearranged, or both. Clonal isolates of these transformants were also superinfectible by infectious MVM virus. Therefore, in spite of their instability, they should be useful host cell lines for transcomplementing mutations introduced into the MVM genome and for growing defective viruses as virions.
A Segmental Partial Laminectomy for Cervical Spondylotic Myelopathy: Anatomical Basis and Clinical Outcome in Comparison With Expansive Open-Door Laminoplasty

Study Design. A comparative study regarding the clinical outcome of the 2-different surgical procedures for patients with cervical spondylotic myelopathy (CSM). Objectives. To describe the anatomic basis of a segmental partial laminectomy (SPL) for the treatment of cervical spondylotic myelopathy and to compare the clinical outcome with traditional C3 to C7 expansive open-door laminoplasty (ELAP). Summary of Background Data. Laminoplasty has been widely accepted for the treatment of CSM. However, some disadvantages have also been recognized. To resolve these problems, a SPL was performed. No previous studies have been reported regarding this surgical procedure. Methods. A total of 13 human cadavers were studied to analyze the spinal cord compression of cervical spondylosis. Twenty-six patients who underwent a SPL and 13 age- and gender-matched patients who underwent traditional C3–C7 ELAP were analyzed for their Japanese Orthopedic Association score, axial neck pain, and radiographic parameters (lordotic angle and ROM of cervical spine). Results. Based on cadaver studies, compression of the spinal cord was present in the articular segment, but not in the intraosseous segment. The removal of the ligamentum flavum and the superior edge of the lower lamina was sufficient for minimum posterior decompression of the cervical spinal cord. In comparison with the ELAP, the patients who underwent an SPL showed a similar recovery of the Japanese Orthopedic Association score, but the maintenance of the sagittal alignment and the range of motion were better after the SPL and postoperative neck and/or shoulder complaints also seemed to be reduced. Conclusion. A SPL, may therefore, be a useful and effective surgical procedure for cervical spondylotic myelopathy.
Improved convergence analysis for the Secant method based on a certain type of recurrence relations

We provide new sufficient conditions for the local as well as semilocal convergence of the secant method in a Banach space. Using a certain type of recurrence relations, we provide a finer convergence analysis than before. Moreover, our conditions compare favourably with earlier ones, which allow us to apply our results in cases not covered before.