Miracle-dz/UniFAR-FTUs huggingface dataset:
Impact of salicylic acid and jasmonic acid on keeping quality of rose ( cv . ‘ Angelina ’ ) flowers

The rose undoubtedly remains the queen of the cut flowers. Most of the commercial cut roses will easily last in a vase for 10 days. Unfortunately, many consumers consider roses to have a very short vase life. The signal molecules salicylic acid (SA), jasmonic acid (JA) and methyl jasmonate (MeJA) are endogenous plant growth substances that play key roles in plant growth and development, and responses to environmental stresses. In this study, effects of various postharvest treatments on postharvest quality and quantity parameters of rose (cv. ‘Angelina’) were evaluated. The present study was carried out in Department of Horticulture, Faculty of Agriculture, Islamic Azad University of Isfahan (Khorasgan) branch. Effects of different levels of jasmonic acid (JA) (0, 50, 100 and 150 ppm) and salicylic acid (SA) (0, 7, 14 and 21 ppm) on rose (cv. ‘Angelina’) quality were quantified. Completely Randomized Factorial Designs was applied to test the significance of treatments and means were compared using Duncan's multiple range test at P = 0.01. Results showed that foliar application of salicylic acid (SA) and jasmonic acid (JA) significantly affected number of flower, diameter of flower, diameter of stalk, stalk length, fresh weight and total chlorophyll contents. About of using salicylic acid (SA), the maximum number of flower, diameter of stalk and total chlorophyll contents obtained at 14 ppm and most of flower diameter, stalk length and fresh weight was obtain in 21 ppm. In jasmonic acid (JA) foliar application best dosage of each material was 50 ppm.
An ergonomic evaluation comparing desktop, notebook, and subnotebook computers.

OBJECTIVE To evaluate and compare the postures and movements of the cervical and upper thoracic spine, the typing performance, and workstation ergonomic factors when using a desktop, notebook, and subnotebook computers. DESIGN Repeated-measures design. SETTING A motion analysis laboratory with an electromagnetic tracking device. PARTICIPANTS A convenience sample of 21 university students between ages 20 and 24 years with no history of neck or shoulder discomfort. INTERVENTION Each subject performed a standardized typing task by using each of the 3 computers. MAIN OUTCOME MEASURES Measurements during the typing task were taken at set intervals. RESULTS Cervical and thoracic spines adopted a more flexed posture in using the smaller-sized computers. There were significantly greater neck movements in using desktop computers when compared with the notebook and subnotebook computers. The viewing distances adopted by the subjects decreased as the computer size decreased. Typing performance and subjective rating of difficulty in using the keyboards were also significantly different among the 3 types of computers. CONCLUSIONS Computer users need to consider the posture of the spine and potential risk of developing musculoskeletal discomfort in choosing computers.
Some Notes on Diagnostic Procedures in Simple and Multiple Linear Regression Profiles Monitoring

Sometimes a relationship between a response variable and one or more explanatory variables known as profile describes the quality of a process. In Phase I, after a control procedure signals the presence of an assignable cause(s), finding the out-of-control samples as well as attributing the shift to model parameters are main objectives. Some diagnostic methods proposed in Phase I analysis of simple and multiple linear profiles. In this article, we modify the procedure by Mahmoud (2008) to improve the method. Moreover, the diagnostic procedure by Mahmoud and Woodall (2004) is discussed. The improvement is illustrated using simulation and numerical examples.
Impacts of bone marrow aspirate and peripheral blood derived platelet-rich plasma on the wound healing in chronic ischaemic limb

Abstract Platelet rich plasma (PRP) has attracted attention as a safe and cost-effective source of growth factors that stimulate cells to regenerate tissue. Bone marrow cells are also estimated as an effective material for treating chronic ulcers. With the same technique to concentrate PRP from peripheral blood, bone marrow aspirate was processed and marrow cells were concentrated as well as platelets. Impact of PRP derived from bone marrow aspirate (bm-PRP) and that from peripheral blood (pb-PRP) on wound healing of persistent ischaemic rabbits' limbs were observed. Full thickness skin defects were made on the thighs, which had been treated to be persistent ischaemic status 3 weeks previously. Saline, pb-PRP, and bm-PRP were injected into the wound floor, respectively. Skin defected areas on ischaemic limbs were significantly wider than those on non-ischaemic limbs. bm-PRP injected wounds showed a significantly smaller skin defect area compared with pb-PRP and ischaemic-saline wounds at all time points. Fluorescently dyed cells of bm-PRP, injected into the wounds, could be traced 4 weeks after, whereas those of pb-PRP could be traced no more than 2 weeks. Wound healing on an ischaemic limb was accelerated with bm-PRP, whereas pb-PRP could not show any significance from saline. This difference can be attributed to the kind of cells contained in the PRPs. Injection of bm-PRP is a good candidate for treating wounds on ischaemic limbs.
Intervertebral disc detection in X-ray images using faster R-CNN

Automatic identification of specific osseous landmarks on the spinal radiograph can be used to automate calculations for correcting ligament instability and injury, which affect 75% of patients injured in motor vehicle accidents. In this work, we propose to use deep learning based object detection method as the first step towards identifying landmark points in lateral lumbar X-ray images. The significant breakthrough of deep learning technology has made it a prevailing choice for perception based applications, however, the lack of large annotated training dataset has brought challenges to utilizing the technology in medical image processing field. In this work, we propose to fine tune a deep network, Faster-RCNN, a state-of-the-art deep detection network in natural image domain, using small annotated clinical datasets. In the experiment we show that, by using only 81 lateral lumbar X-Ray training images, one can achieve much better performance compared to traditional sliding window detection method on hand crafted features. Furthermore, we fine-tuned the network using 974 training images and tested on 108 images, which achieved average precision of 0.905 with average computation time of 3 second per image, which greatly outperformed traditional methods in terms of accuracy and efficiency.
Planning and executing an action in Parkinson's disease

We evaluated the possible impairment in planning and executing an action in patients with Parkinson's disease (PD). The action considered in the present study was formed by two successive motor acts: reaching‐grasping an object (first target) and placing it on a second target of the same shape and size. We examined the effects of extrinsic properties of the second target (that is, distance) on the various kinematic phases of reaching‐grasping movements. Distance, position, and size of both stimuli were randomly varied across the experimental session. Movements were executed with and without visual control of both targets and arm. The performance of six patients with PD was compared with an age‐matched control group. The kinematics of the initial phase of reaching was influenced by position and size of the first target and by distance of the second target in both patients and control subjects. In particular, peak acceleration was higher for farther position of the second target. However, in the subsequent phase patients, differently from control subjects, removed the effects of the second target distance by modifying their reaching kinematics. This was obtained by varying the duration of the acceleration phase. In summary, the patients reprogrammed the reaching component by taking into account only the properties of the first target. The decreasing influence of second‐target distance on reaching kinematics of patients was more evident during movements executed under visual control. Moreover, their movements executed without visual control were slowed down from the beginning. The second target affected the grasping kinematics only of the control subjects. Globally, these results indicate that PD patients are able to compute the general program of an action that takes into account extrinsic properties of the final target. However, the finding that PD patients reprogrammed the movement during its execution suggests a decay of the program during its time course, that is, basal ganglia can be involved in storing the plan of an action and in controlling its correct execution.
Serum Iron Values following Myocardial Infarction

This is a study of serum iron levels following myocardial infarction in a series of 18 male and 10 female patients. All showed hypoferraemia, which was variable in time of onset, intensity and duration, but was commonly sustained and severe. This was not of prognostic significance, and the Victoria Infirmary coronary prognostic index remains the most reliable prognostic guide.
Polycation-mediated delivery of siRNAs for prophylaxis and treatment of influenza virus infection

Influenza A virus causes one of the most prevalent infections in humans. In a typical year, 10 – 20% of the population of the US is infected by influenza virus, resulting in up to 40,000 deaths and 200,000 hospitalisations. Vaccination is the most effective preventative measure that can protect 70 – 90% of healthy adults aged < 65; however, the protection rate is much lower in those most susceptible to infection, namely infants, the elderly and individuals with weakened immune systems. Although four drugs have been approved by the FDA for use as prophylaxis and/or treatment of influenza, concerns about their side effects and the emergence of drug-resistant viruses persist. RNA interference (RNAi), an emerging method of post transcriptional gene silencing, appears ideal for the prevention and treatment of influenza. RNAi in mammals can be mediated by short interfering RNAs (siRNAs) of ∼21– 27 nucleotides in length. The authors have previously shown that si-RNAs specific for conserved regions of the influenza virus genome are potent inhibitors of influenza virus replication in both cell lines and chicken embryos. This review discusses the recent progress in the invivo inhibition of influenza virus by the delivery of siRNAs mediated by non-viral vectors, and the prospects of this strategy for prophylaxis and treatment of influenza infection in humans.
Tetracycline does not directly inhibit the function of bacterial elongation factor Tu

Understanding the molecular mechanism of antibiotics that are currently in use is important for the development of new antimicrobials. The tetracyclines, discovered in the 1940s, are a well-established class of antibiotics that still have a role in treating microbial infections in humans. It is generally accepted that the main target of their action is the ribosome. The estimated affinity for tetracycline binding to the ribosome is relatively low compared to the actual potency of the drug in vivo. Therefore, additional inhibitory effects of tetracycline on the translation machinery have been discussed. Structural evidence suggests that tetracycline inhibits the function of the essential bacterial GTPase Elongation Factor (EF)-Tu through interaction with the bound nucleotide. Based on this, tetracycline has been predicted to impede the nucleotide-binding properties of EF-Tu. However, detailed kinetic studies addressing the effect of tetracycline on nucleotide binding have been prevented by the fluorescence properties of the antibiotic. Here, we report a fluorescence-based kinetic assay that minimizes the effect of tetracycline autofluorescence, enabling the detailed kinetic analysis of the nucleotide-binding properties of Escherichia coli EF-Tu. Furthermore, using physiologically relevant conditions, we demonstrate that tetracycline does not affect EF-Tu’s intrinsic or ribosome-stimulated GTPase activity, nor the stability of the EF-Tu•GTP•Phe-tRNAPhe complex. We therefore provide clear evidence that tetracycline does not directly impede the function of EF-Tu.
LONG-TERM FOLLOW-UP OF COLLES'S FRACTURE.

1. A five-year follow-up of forty-one patients who sustained Colles9s fractures was made. 2. The objective results were not so satisfactory as the subjective, but overall there seems to be no reason to depart from the present methods of managing these injuries by manipulation and immobilisation in plaster. 3. Colles9s belief that in time the patient would regain full painless function irrespective of how the fracture was treated seems to be vindicated.
Hysterectomy on benign indications in Sweden 1987–2003: A nationwide trend analysis

Objective. To investigate the annual rates, types and indications for hysterectomy on benign indications in Sweden 1987–2003. Design. A nationwide register‐based cohort study. Setting. The Swedish Inpatient Register. Population. All women hysterectomized for benign disease in Sweden from 1987 through 2003 (n = 121,947). Main outcome measure. Hysterectomy on benign indications calculated as proportions or rates/100,000 person‐years. Results. From 1987 to 1999, the annual overall hysterectomy rate increased from 178 to 232/100,000 person‐years. Thereafter, the overall hysterectomy rate declined and phased out around 210/100,000 person‐years in 2003, a decrease of 11%. Comprising only 4% of hysterectomies performed in 1987, vaginal hysterectomy increased to 31% in 2003. Rates of vaginal hysterectomy by prolapse indication increased by a five‐fold, whereas rates of vaginal hysterectomy by other benign indications increased by a near 20‐fold. Total and subtotal abdominal hysterectomy decreased from 63% and 32%, respectively, in 1987, to 48% and 18% in 2003. Conclusion. The overall rate of hysterectomy on benign indications has remained reasonably stable in Sweden over the last decade. Major trends involved a considerable decrease in rates of abdominal hysterectomy, increased use of vaginal hysterectomy and increased number of hysterectomies performed for pelvic organ prolapse.
Oral tolerance in a murine model of relapsing experimental autoimmune uveoretinitis (EAU): induction of protective tolerance in primed animals

Oral administration of uveitogenic retinal antigens suppresses the expression of EAU induced by a subsequent immunization with these antigens. Effectiveness and mechanisms of oral tolerance in EAU have mainly been studied in the acute, monophasic model in Lewis rats by feeding antigen prior to induction of disease. In this study we investigated the effect of oral tolerance induction in the acute as well as the chronic‐relapsing models in the B10.A mouse. In acute murine EAU we could effectively suppress disease by induction of oral tolerance prior to immunization. In the chronic‐relapsing EAU, antigen feeding was started only after the animals had recovered from their first attack of uveitis. Under these experimental conditions the subsequent relapse was largely prevented. These experiments demonstrate that oral tolerance may have practical clinical implications in uveitis, which is predominantly a chronic‐relapsing condition in humans.
A 0.12mm2 7.4μW micropower temperature sensor with an inaccuracy of ±0.2°C (3σ) from −30°C to 125°C

A temperature sensor intended for RFID applications has been realized in a 0. 16μm standard CMOS process. After a single digital trim at 30°C, it achieves an inaccuracy of ±0.2°C (3σ) over the temperature range: −30°C to 125°C. At a conversion rate of 10Hz, it achieves a resolution of 15mK. The sensor is compact, occupying only 0.12mm<sup>2</sup>, and power efficient, drawing 4. 6μA from a 1.6V to 2V supply, which corresponds to a minimum power dissipation of 7. 4μW, the lowest ever reported for a precision temperature sensor.
Systemic Toxicity From Subchronic Dermal Exposure, Chemical Characterization, and Dermal Penetration of Catalytically Cracked Clarified Slurry Oil

Clarified slurry oil (CSO), the heavy residual fraction from the fluidized catalytic cracker, was applied to the shaven backs of groups of 10 male and 10 female Sprague-Dawley rats 5 days/week for 13 weeks at doses of 8, 30, 125, or 500 mglkglday, and to another group for 2 weeks at doses of 2000 mg/kg/day. The rats were fitted with cardboard Elizabethan collars to minimize the ingestion of the test material, which was applied undiluted and remained uncovered on the skin. A similar group of rats served as controls; they were treated in the same manner except that no CSO was applied to their skin. There was a dose-related mortality and depression of body weight gain in the rats treated with CSO at doses of 30 mg/kg/day or greater; none of the rats dosed at 2000 mg/kg/day survived more than 2 weeks. The primary target organs ofCSO toxicity were the liver, thymus, and bone marrow. The effects on the liver included increased weight (250% at 500 mg/kg/day), cholangiolitis, diffuse liver cell degeneration and hypertrophy, necrosis, fibrosis, decreased serum glucose, increased levels of alkaline phosphatase, aspartate aminotransferase, alanine amino transferase, bilirubin, and triglycerides. The thymus was found to be small and upon microscopic examination to be atrophic or hypoplastic. Erythroid hypo plasia was found in the bone marrow of some of the rats dosed at 30 mg/ kg/day and increased in severity with increasing dose. The erythroid hypoplasia was accompanied by a dose-related anemia. Even in the rats dosed at 8 mg/kg/day, very slight abnormalities in the bile ducts were observed upon microscopic examination of the liver. Chromato-graphic separation and analyses demonstrated that CSO contains about 58% 3- to 5-ring polycyclic aromatic hydrocarbons (PAHS) and ap proximately 8-10% carbazole derivatives. In vitro and in vivo skin penetration studies demonstrated that the carbazole materials penetrate through the skin to a considerable extent (about 44 %) ; less penetration was observed with 2- or 3-ring (8-13%) or 5-ring PAHs (3%).
Vergleichende morphologische Studien über Stomata und eine neue Klassifikation ihrer Typen

Zusammenfassung Mehr und mehr nehmen Studien uber Stomata, ihre Strukturen, Typen und Entwicklungen einen wichtigen Platz in der botanischen Literatur ein. Im vorigen Jahrhundert begrundete Vesque (1889) eine Klassifikation der Stomatatypen, doch haben 1950 Metcalfe und Chalk eine neue Terminologie “devoid of taxonomic or ontogenetic implications” vorgeschlagen. Spater wurden Bezeichnungen fur weitere Typen von Metcalfe (1961) und Stace (1963, 1965) vorgeschlagen. Unsere eigenen vergleichend morphologischen Studien uber die Stomata bei Farnen haben gezeigt, das hier mindestens funf Typen von denen der Angiospermen verschieden sind. Diese funf Typen sind ebenfalls benannt und beschrieben, zwei von ihnen dabei weiter unterteilt worden (Van Cotthem 1968, 1970a) Drei weitere Bezeichnungen haben wir vorgeschlagen, um unsere Klassifikation durch weitere Typen bereichern zu konnen (Van Cotthem 1970b). Payne (1970) hat zwei neue Typen bei den Dikotylen gefunden. Fur einen der beiden hat er eine Unterteilung in zwei Untertypen vorgeschlagen Insgesamt konnen nunmehr 17 Typen unterschieden werden Nach unseren Untersuchungen lassen sich jetzt die meisten der bei Metcalfe und Chalk (1950, p. 1333) noch als “special types” angefuhrten Stomataformen ohne Schwierigkeiten in unserer neuen Klassifikation der Stomatatypen (Van Cotthem 1970b) einordnen
Utility of ferritin as a predictor of the patients with Kawasaki disease refractory to intravenous immunoglobulin therapy

Objectives. The aim of this study is to investigate whether ferritin can be a useful marker for the prediction of the patients with Kawasaki disease (KD) refractory to initial intravenous immunoglobulin (IVIG) therapy. Methods. This retrospective study enrolled 85 patients with KD hospitalized at Kitakyushu General Hospital during 2010–2014. These patients were divided into IVIG responders (n = 57) and non-responders (n = 28). Serum ferritin levels and the scoring systems for the prediction of non-responsiveness to initial IVIG therapy were compared between these two groups. Results. Serum ferritin level was significantly elevated in non-responders (p = 0.010). The area under the receiver-operating characteristics curve was 0.674, and the sensitivity and specificity in more than 165 ng/ml of serum ferritin level were 70.4% and 63.2%, respectively. In two of the three prediction scoring systems, non-responders also showed significantly higher scores than responders, but many non-responders had low scores of these scoring systems. More than half of the patients with a low score of these scoring systems had high serum ferritin level (≥ 165 ng/ml). Conclusions. Serum ferritin level might be a useful marker for the prediction of non-responsiveness to initial IVIG therapy and could be an important complementary marker to the prediction scoring systems.
Cyclic Voltammetric Measurements of Growth of Aspergillus terreus

A detailed study using the cyclic voltammogram was done on the live cells of Aspergillus terreus . The peak current values were obtained for different days of growth and plotted against time. The response of cyclic voltammogram showed the phases of the growth of the fungus. The growth curve obtained matched well with the conventional methodology, which assesses the increase of dry weight of the organisms against time. The electrochemical method is more advantageous because it is easy to assess and consumes less time. Further the electrochemical method clearly shows the decline phase which is generally not very defined in the conventional method of assessment of the growth curve. It was confirmed by further experiments that the metabolites were responsible for the anodic peak and not the biomass. Further work is in progress in order to analyze the metabolite(s) that is/are responsible for the anodic peak.
The relation of immune depression and B-cell stimulation during the development of delayed hypersensitivity to soluble antigens.

A comparison has been made of the effects of cyclophosphamide (CY) pretreatment and i.v. injection of a high dose of antigen on delayed hypersensitivity induced by proteins in Freund's incomplete and complete adjuvants. Five antigens have been studied: obalbumin (OA), bovine serum albumin (BSA) bovine gammaglobulin (BGG), DNP 5-BGG and DNP 50-BGG. A spectrum of reactivity has been detected depending upon the ability of the antigen to stimulate B-cell as well as T-cell activity. Bovine serum albumin and BGG behave as relatively weak antigens in which the T-cell response, measured by delayed hypersensityity, is easily suppressed by i.v. antigen and the B-cell modulating system, revealed by CY sensitivity, is poorly stimulated. These proteins, injected i.v. , are weak stimulators of antibody-dependent Arthus reactions. On the other hand, OA, DNP 5-BGG and DNP 50-BGG behave as strong antigens, resisting suppression of the T-cell response by soluble antigen and exhibiting (in Freund's incomplete adjuvant) a strongly developed CY sensitive, B-cell modulating system. Strong Arthus reactivity is readily demonstrated following i.v. administration of these antigens. A dissociation has been demonstrated between B-cell modulation of T-cell function and unresponsiveness induced by i.v. antigen. The failure to reverse the latter type of unresponsiveness by cyclophosphamide pretreatment suggests that separate mechanisms are involved in these systems.