Miracle-dz/UniFAR-FTUs huggingface dataset:
Relationships of Approaches to Studying, Metacognition, and Intellectual Development of General Chemistry Students.

This study investigated approaches to studying, intellectual developments, and metacognitive skills of general chemistry students enrolled for the spring 2011 semester at a single campus of a multi-campus community college. the three instruments used were the Approaches and Study Skills Inventory for Students (ASSIST), the Learning Environment Preferences (LEP), and the Executive Process Questionnaire (EPQ). the subjects were 138 students enrolled in either general chemistry 1 or 2. the results revealed that the preferred approach to study was the strategic approach. the intellectual development of the students was predominantly Perry’s position 2 (dualist) in transition to position 3 (multiplicity). Correlation statistics revealed that deep approach to studying is related to effective employment of metacognitive skills. Students with a deep approach to studying were likely to utilize effective metacognitive skills. Students with a surface approach to studying used no metacognitive skills or ineffective metacognitive skills. Multiple logistic regression analysis was conducted to ascertain which of the three variables, namely approaches to studying, ability to metacognate, or level of intellectual development, was the most salient in predicting the success of general chemistry students. No single variable was found to predict students’ success in general chemistry classes; however, a surface approach to studying predisposes general chemistry students to fail. the implication of this study is that students’ study approaches, intellectual developments, and metacognitive skills are requisite information to enable instructional remediation early in the semester.
The binding of complement component C3 to antibody-antigen aggregates after activation of the alternative pathway in human serum.

Preformed immune aggregates, containing antigen and either IgG (immunoglobulin G) or F(ab')2 rabbit antibody, were incubated with normal human serum under conditions allowing activation of only the alternative pathway of complement. Both the IgG and F(ab')2 immune aggregates bound C3b, the activated form of the complement component C3, in a similar manner, 2-3% of the C3 available in the serum being bound to the aggregates as C3b, and the rest remaining in the fluid phase as inactive C3b or uncleaved C3. It was found that the C3b was probably covalently bound to the IgG in the aggregates, since C3b-IgG complexes could be demonstrated on sodium dodecyl sulphate/polyacrylamide-gel electrophoresis, after repeated washing with buffers containing high salt or boiling under denaturing conditions. Incubation of the C3b-antibody-antigen aggregates in buffers known to destroy ester linkages had little effect on the C3b-IgG complexes, which suggested that C3b and IgG might be linked by an amide bond. Two main types of C3b-IgG complexes were found that had apparent mol.wts. of 360000 and 580000, corresponding to either one to two C3b molecules respectively bound to one molecule of antibody. On reduction of the C3b-IgG complexes it was found that the beta-chain, but not the alpha'-chain, of C3b was released along with all the light chain of IgG but only about half or less of the heavy chain of IgG. These results indicate that, during activation of the alternative pathway of complement by immune aggregates containing IgG antibody, the alpha'-chain of C3b may become covalently bound at one or two sites in the Fd portion of the heavy chain of IgG.
Studying Pull Request Merges: A Case Study of Shopify's Active Merchant

Pull-based development has become a popular choice for developing distributed projects, such as those hosted on GitHub. In this model, contributions are pulled from forked repositories, modified, and then later merged back into the main repository. In this work, we report on two empirical studies that investigate pull request (PR) merges of Active Merchant, a commercial project developed by Shopify Inc. In the first study, we apply data mining techniques on the project's GitHub repository to explore the nature of merges, and we conduct a manual inspection of pull requests; we also investigate what factors contribute to PR merge time and outcome. In the second study, we perform a qualitative analysis of the results of a survey of developers who contributed to Active Merchant. The study addresses the topic of PR review quality and developers' perception of it. The results provide insights into how these developers perform pull request merges, and what factors they find contribute to how they review and merge pull requests.
Automotive Electrification: The Nonhybrid Story

The electrification of the automobile has a long history. Electric and hybrid vehicles are actually only a small part of it, albeit presently the most visible and the one getting the most attention in popular media. This paper will focus on the rest of the story, i.e., aspects of transportation electrification other than hybrid or fully electric propulsion systems. Recent progress (last 10-20 years) and current work on the electrification of road transport, from chassis to powertrains, will be reviewed with a focus on electromechanical systems. In the process, the numerous challenges engineers have overcome or have yet to solve will be highlighted, thus illustrating the many different ways electrical engineering is making its mark in providing more performant, more efficient, safer, and more pleasant means of personal transportation.
Development of a new case based computer-aided detection scheme for screening mammography

In this study, we examine a new case based approach to computer-aided detection (CAD) schemes of screening mammograms based on the computation of many global bilateral asymmetry and mammographic density image based features. The current commercialized CAD schemes have high false positive detection rates, which also have high positive lesion detection correlations with radiologists. Thus, we developed a new global image feature based CAD scheme that can cue the warning sign on the cases with high risk of being positive using an extended feature set of 158 mammographic density and texture based features computed on all four craniocaudal (CC) and mediolateral oblique (MLO) view images. We utilized a modified fast and accurate sequential floating forward selection feature selection algorithm and applied selected features to a “scoring fusion” artificial neural network (ANN) classification scheme to produce a final case based classification score. We tested our methods using a ten-fold cross-validation scheme on 924 cases (476 cancer and 448 recalled or negative). The area under the receiver operating characteristic curve was AUC = 0.742±0.016. Odds ratios increased from 1 to 15.43 as the CAD-generated case based detection scores increased. The results of the study show that useful information can be derived from the global mammographic density image based features that can be examined further as a new paradigm/approach of CAD for screening mammograms.
Comparison of basic nutritive components of venison in selected species of hoofed game

The aim of this experiment was to obtain the differences in protein, moisture and fat content in venison (Mucsulus semimembranosus) of roe deer (Capreolus capreolus L.) and wild boar (Sus scrofa L). The monitoring of wild boar and roe deer was realized from 16 May 2016 to 16 June 2016 in red deer region JXXVIII Tribec (Western Slovakia, Tribec mountain). Analysis of basic nutritive components of venison were determined with FoodScan LAB Analyzer (FOSS, Denmark). The obtained average values of experimental traits were as follows: wild boar – 23.33%, roe deer – 21.55% in protein, respectively 2.46% and 1.8% in fat. The difference in fat content shows significant importance. Moisture was not statistically significant (average: wild boar – 73.2%, roe deer – 72.9%).
A brief introduction to weakly supervised learning

Supervised learning techniques construct predictive models by learning from a large number of training examples, where each training example has a label indicating its ground-truth output. Though current techniques have achieved great success, it is noteworthy that in many tasks it is difficult to get strong supervision information like fully ground-truth labels due to the high cost of the data-labeling process. Thus, it is desirable for machine-learning techniques to work with weak supervision. This article reviews some research progress of weakly supervised learning, focusing on three typical types of weak supervision: incomplete supervision, where only a subset of training data is given with labels; inexact supervision, where the training data are given with only coarse-grained labels; and inaccurate supervision, where the given labels are not always ground-truth.
Virus-Induced IL-8 Gene Expression Element in Respiratory Syncytial Requirement of a Novel Upstream Response

Respiratory syncytial virus (RSV) produces intense pulmonary inﬂammation, in part, through its ability to induce chemokine synthesis in infected airway epithelial cells. In this study, we compare mechanisms for induction of the CXC chemokine IL-8, in human type II alveolar (A549) cells by RSV infection and by stimulation with the cytokine TNF. Promoter deletion and mu-tagenesis experiments indicate that although the region from 2 99 to 2 54 nt is sufﬁcient for TNF-induced IL-8 transcription, this region alone is not sufﬁcient for RSV-induced IL-8 transcription. Instead, RSV requires participation of a previously unrecognized element, spanning from 2 162 to 2 132 nt, that we term the RSV response element (RSVRE), and a previously characterized element at 2 132 to 2 99 nt, containing an AP-1 binding site. RSV infection of A549 cells induces increased RSVRE- and AP-1-binding activities and increased synthesis of IFN regulatory factor-1 protein, which is present in the RSVRE-binding complex . These data conﬁrm that the IL-8 gene enhancers are controlled in a stimulus-speciﬁc fashion and participation of distinct promoter elements is required to activate gene transcription. These observations are important for rational design of inhibitors of RSV-induced lung inﬂammation. The Journal of Immunology, 2000, 164: 5944–5951.
High frequency N-polar GaN planar MIS-HEMTs on sapphire with high breakdown and low dispersion

N-polar planar GaN metal-insulator-semiconductor high-electron-mobility transistors (MIS-HEMTs) grown by metal-organic chemical vapor deposition on sapphire substrate with a high combination of power cutoff frequency (fmax) and three-terminal breakdown voltage (BVDS) as well as a decent DC-to-RF dispersion control are demonstrated. Compared to previously reported N-polar planar HEMTs, devices presented in this letter not only maintain comparable fmax/BVDS of 221 GHz/116 V, but also exhibit a mitigation of drain current collapse and ON-resistance dispersion. In addition, a higher output power of 5.43 W/mm at the same VDS,Q = 25 V and a reduction of efficiency drop with increasing VDS,Q were achieved by load-pull measurements at 10 GHz.
Investigation of performance limits of germanium double-gated MOSFETs

The performance limits and engineering issues of ultra-thin body (UTB) double gated (DG) Ge channel n-MOSFETs are examined in this paper. The non-equilibrium Green's Function (NEGF) approach, including both L and /spl Delta/ conduction valleys, is employed for source to drain current, while the improved WKB tunneling is employed for substrate to drain (band-to-band BTB) and gate to channel current. All possible Ge surfaces and channel orientations are explored. Our results conclude that in addition to lower power supply voltage advantages, the engineered Ge<110> devices with suppressed BTB and gate leakages can achieve better intrinsic delay to OFF power ratio than Si<100> devices.
Microbiome Metagenomic Analysis of the Human Distal Gut

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PHENYTOIN INDUCED ERYTHEMATOSUS RASH IN A DIABETIC SEIZURE PATIENT

Article history This is a case report of 1 year old male patient, who has experienced rashes after the use of phenytoin for the treatment of seizures. The blood glucose level of the patient was high, which may have triggered seizure in the patient. This type of seizure is known as diabetic seizure. Phenytoin is a hydantoin compound related to the barbiturates that are used for the treatment of seizures. It is one of the most commonly used anticonvulsant drugs. These drugs frequently cause cutaneous eruptions, especially during inception of new therapy. In addition to causing common and usually limited morbilliform and urticarial eruptions, which have often mild morbidity. In this case, the patient has developed erythematosus rash all over the body on the fifth day after administration of phenytoin. This ADR (Adverse drug reaction) has scored 6 points on naranjo scale of causality assessment. The possible reason for the adverse drug reaction was found to be the drug over-dose.
Editorial . Stalking : the state of the SClence

When Louisa May Alcott penned A Long Fatal Love Chase the first stalking novel ever written in 1866, perhaps her imagination was piqued by the thought that the study of stalking would become a scientific endeavour filled with the passion of pursuit 150 years later. It has become just that. Since the behaviour of stalking was criminalized in California in 1990, a brief interlude of 15 years has seen the publication of 175 studies of stalkers and their victims worthy of meta-analysis (Spitzberg, 2006), and the world's scientific literature on stalking is bolstered by dozens of new studies each year. What have we learned, and where should we go from here? Although defini­ tions of the crime of stalking vary, there seems to be a legal consensus that three elements are necessary: an intentional activity, a credible threat and the induc­ tion of fear in the victim. Various definitions of these elements exist across state and federal jurisdictions in North America, Australia, New Zealand and Europe, and it seems apparent that there must be a pattern of unwanted pursuit, the behaviour must pose an implicit or explicit threat to the safety of the victim, and the victim must experience fear as a result of the intentional behaviour of the pursuer (Dennison and Thomson, 2005). Although the constitutionality of stalk­ ing laws continues to be argued in courts of appeal, particularly in the United States, it appears that this very old behaviour, which is now a new crime, is here to stay (Meloy, 1999). To those of us with an intense interest in the motivation and meaning of behaviour, stalking is a remarkably intriguing activity whose interpersonal and intrapsychic dynamics easily subsume the legal debates: why, on earth, would someone want to pursue another who shows absolutely no interest in his or her attentions! The answer to this fundamental question, and other related queries, helps us to understand the state of the science and to propose directions for future research.
The Study on the Efficacy of Topical Vitamin K Versus 5% Urea on Laser-induced Purpura

Background: Purpura is a common adverse effect of dermatological procedures and can compromise the patients’appearance especially when they occur on the face. Topical vitamin K oxide has been known to be effective in treatment of purpura from vascular laser and minor surgical procedures. However its effectiveness on purpuric skin with minimal ablation produced by Q-switched Nd-YAG laser has not been studied Methods: Twenty volunteers had two areas of skin lasered on the upper inner arm using Q-switched Nd:YAG 1064nm laser at slightly purpuric settings. Vitamin K and 5% urea cream were blindly applied to the purpura twice daily as randomly allocated for 10 days. Photographs were taken on days 0, 1,2,4,8, and 10. Improvement of purpura using VAS and adverse effects were recorded. Results: Twenty volunteers with average age of 35.9 years completed the study. Evaluation by investigators showed no difference in reduction of purpura between the 2 regimens although vitamin K showed a faster onset. Interestingly subjects detected fading of the vitamin K-applied site significantly from the 2nd day after application. All lesions eventually lightened by the 6th day. Conclusion: In this study topical vitamin K oxide induced lightening of purpura faster than 5% urea cream.
NAPPA-Based Nanobiosensors for the Detection of Proteins and of Protein-Protein Interactions Relevant to Cancer

In this manuscript, we report some proofs-of-principle and preliminary applications and results regarding the analytical quantification of protein expression of some genes biologically and clinically related to cancer. Experiments have been carried out coupling Nucleic Acid Programmable Protein Array (NAPPA) with a recently improved nanogravimetric apparatus which exploits the quartz crystal microbalance with frequency (QCM_F) and quartz crystal microbalance with dissipation monitoring (QCM_D) technologies. The selected proteins are BRIP1, JUN and ATF2. Clinically relevant implications for cancer are envisaged and discussed, as well as future perspectives and developments.
A Two-Port Nonlinear Dynamic Behavioral Model of RF PAs Subject to Wideband Load Modulation

This work presents a full two-port, i.e., double input-double output, behavioral modeling approach suitable for radio frequency power amplifiers (PAs) in the presence of dynamic load modulation (DLM). The formulation of the model, based on a first-order approximation of a modified Volterra series, accounts for the nonlinear distortion determined by large-signal operation under mismatched conditions, and also for the memory effects stimulated by a modulated PA input signal, or by the dynamic variations of the PA load. By following an exhaustive procedure defined in the frequency domain, the model of a general purpose commercial PA is extracted over 160 MHz of modulation bandwidth (BW) with nonlinear vector network analyzer measurements. Validation results under 20-MHz BW multisine excitation and injected 80-MHz BW multisine load modulation show improved prediction capabilities with respect to quasi-static or single-input descriptions, allowing for reliable system-level simulations in the presence of DLM.
Buckling and free oscillations of composite microresonators

Free oscillations of piezoelectric, microelectromechanical resonators are considered in this effort. These resonators are modeled as clamped-clamped composite structures, with stepwise varying properties across the length of the resonator. The different features of the model development are discussed, and buckling in these resonators is studied. A nonlinear analysis conducted to study oscillations about a buckled position is presented. The results of the analysis are found to compare well with the experimental observations.
RELATION OF HEMOGLOBIN A 1C TO LEFT VENTRICULAR DIASTOLIC FUNCTION IN PATIENTS WITH TYPE 1 DIABETES MELLITUS AND WITHOUT OVERT HEART DISEASE

SUMMARY Left ventricular diastolic dysfunction is a main feature of diabetic heart disease. The aim of this prospective study was to evaluate the relation of hemoglobin A 1c and diastolic function in type 1 diabetes mellitus. We examined echocardiographic studies of 25 patients with type 1 diabetes without clinical evidence of heart disease and 25 healthy ageand sex-matched normal individuals. In patients with type 1 diabetes, there was a diastolic dysfunction with lower transmitral E/A (1.28±0.3 vs. 1.6±0.3; p=0.01), more prolonged isovolumic relaxation time (99±11 vs. 71±8, p=0.003) in comparison with normal subjects. Furthermore, HbA 1c correlated with diastolic indices. These results demonstrate that asymptomatic diastolic dysfunction is common in patients with type 1 diabetes mellitus and that its severity correlates with glycemic control.
What You Don ’ t Know Can Hurt You : Situationism , Conscious Awareness , and Control

Biography Marcela Herdova is Visiting Professor at Florida State University. She previously worked as Research Associate on the “Self-Control and the Person: A Multi-Disciplinary Account” project at King’s College London and as Postdoctoral Research Fellow in Free Will and Self-Control at Florida State University. Her research interests include action theory, free will, moral psychology, consciousness and applied ethics.
Neuropsychological Deficits, Depression and Type a Behavior Pattern in Patients with Myocardial Infarction

In cardiovascular disease, which is one of the leading causes of death in developing countries, the majority of deaths are due to myocardial infarction (MI). Myocardial infarction occurs when the blood supply to parts of the heart is interrupted causing some heart cells to die. Myocardial infarction may lead to cognitive deficits. The main causes or risk factors of myocardial infarction are hypertension, diabetes mellitus and tobacco use. Psychosocial factors such as Type A behavior pattern or coronary prone behavior and depression have been reported to be associated with myocardial infarction. The aim of the present study was to examine the presence of depression and neuropsychological deficits in patients with myocardial infarction. In addition, Type A behavior pattern or coronary prone behavior of patients with MI was also examined. The sample consisted of 40 MI patients and the tests were administered within one week after hospitalization. A healthy normal comparison group of 40 subjects, who were matched with respect to age, education, gender, place and state of residence with the MI patient group, was also selected for the study. The tools used were Beck depression inventory, Edinburgh Handedness inventory, Type A/B behaviour pattern scale, General Health Questionnaire, and tests from NIMHANS Neuropsychological test battery. The results showed that neuropsychological performances of the MI patient group were significantly poor in the domains of mental speed and information processing; sustained attention; executive functions: category fluency, phonemic fluency, verbal working memory and response inhibition; verbal learning and memory; visual learning and memory; and visuo-spatial ability compared to the healthy normal matched group. Moreover, 52.5% of the MI patients were depressed. Type A behavior was significantly linked to myocardial infarction. The cognitive deficits and depression which are seen in the present study might have resulted from the disruption of neural networks that connect cortical and subcortical regions of the brain. Index Terms—Myocardial infarction, type a behavior, depression.