Miracle-dz/UniFAR-FTUs huggingface dataset:
Synthesis Of Air Stable Copper Nanoparticles And Their Use In Catalysis

The undertaken study describes synthesis of air resistant copper nanoparticles (Cu NPs) in an aqueous phase using sodium borohydride as a reducing agent via chemical reduction method. The hydrosol has resistant to oxidation by atmospheric oxygen for several days. The air stability was induced by capping Cu NPs with anionic surfactant “sodium dodecyl sulfate (SDS)”. Ascorbic acid was used as an antioxidant. These Cu NPs were characterized by ultraviolet-visible (UV-VIS) spectroscopy, which contributed towards the understanding of surface plasmon resonance (SPR) generation and optical behavior of Cu NPs. It was used as an optical tracer for size control and confirmation of Cu NPs and was found to be affected by various parameters like reaction time, pH, concentration of copper sulfate and the surfactant SDS. SPR peaks were found to shift from 597 to 569 nm, while apparent color changes from yellow to brick red. Further characterization studies were carried out by using fourier transform infrared (FT-IR) spectroscopy to investigate the co-ordination between Cu NPs and SDS. X-ray diffraction (XRD) was used for phase purity of Cu NPs. Transmission electron microscopy (TEM) and atomic force microscopy (AFM) were used the size and morphological characterization. The average size of the Cu NPs was found to be 15 nm in diameter with an average height of 14 nm. The Cu NPs showed excellent catalytic activity in the reductive degradation of Eosin B (EB) dye in just 16 sec of reaction time and maintained their catalytic activity when reused multiple times. The degradation rate was found to follow first order reaction kinetics with the EB degradation. The Cu NPs enhanced the rate of EB degradation 30 times more than the control test. Copper was found an attractive catalyst in the nanosize regimes. The Cu NPs are more economical as compared to noble metals. The Cu NPs are expected to be suitable alternative and play an imperative role in the fields of catalysis and environmental remediation. Copyright © 2014 VBRI press.
Virgin soil in irony research: Personality, humor, and the “sense of irony”.

he aim of the paper is fourfold: (a) show why humor scholars should study irony, (b) explore the need for considering interindividual differences in healthy adults’ irony performance, (c) stress the necessity for developing tools assessing habitual differences in irony performance, and (d) indicate future directions for joint irony and humor research and outline possible applications. Verbal irony is often employed with a benevolent humorous intent by speakers, but can also serve as a means of disparagement humor. In both cases, encoding and decoding activities entailing irony need to be considered in the context of the psychology of humor. We argue that verbal irony performance can be considered a phenomenon native to the realm of humor and individual differences. We point out that research has widely neglected the meaningfulness of variance in irony performance within experimental groups when looking at determinants of irony detection and production. Based on theoretical considerations and previous empirical findings we show that this variance can be easily related to individual-differences variables such as the sense of humor, dispositions toward laughter and ridicule (e.g., gelotophobia), and general mental ability. Furthermore, we hypothesize that there is an enduring trait determining irony performance we will label the sense of irony. The sense of irony possibly goes along with inclinations toward specific affective and cognitive processing patterns when dealing with verbal irony. As an application, novel irony performance tests can help to study psychological and neurophysiological correlates of irony performance more feasibly, that is, in nonclinical groups. DOI: https://doi.org/10.1037/tps0000054 Posted at the Zurich Open Repository and Archive, University of Zurich ZORA URL: https://doi.org/10.5167/uzh-124094 Accepted Version Originally published at: Bruntsch, Richard; Hofmann, Jennifer; Ruch, Willibald (2016). Virgin soil in irony research: Personality, humor, and the “sense of irony”. Translational Issues in Psychological Science, 2(1):25-34. DOI: https://doi.org/10.1037/tps0000054 VIRGIN SOIL IN IRONY RESEARCH 1 Running head: VIRGIN SOIL IN IRONY RESEARCH Virgin soil in irony research: Personality, humor, and the “sense of irony”
Large Shareholders and Corporate Policies

We analyze the effects of heterogeneity across large shareholders, using a new blockholder-firm panel dataset in which we can track all unique blockholders among large public firms in the United States. We find statistically significant and economically important blockholder fixed effects in investment, financial, and executive compensation policies. We also find blockholder fixed effects in firm performance measures, and differences in corporate policies are systematically related to differences in firm performance. We study potential sources of the heterogeneity and find that blockholders with a larger block size, board membership, direct management involvement, or with a single decision maker are associated with larger effects on corporate policies and firm performance.
Pediatric Acute Blastic Natural Killer Cell Leukemia

The goal of this report is to describe a rare case of pediatric blastic natural killer (NK) cell leukemia and to compare pediatric blastic NK cell leukemia/lymphoma to other reported cases of pediatric NK cell leukemia. The patient, a 9-year-old girl, presented with acute leukemia with a phenotype similar to adult blastic NK cell leukemia/lymphoma. The blasts were agranular and expressed CD7, 45, 56, and HLA-DR, but not CD3, 11c, 13, 33, or TdT. She had a complete response to ALL-directed chemotherapy, but had multiple relapses involving the cerebrospinal fluid, nasal sinus, lymph node and skin. In addition to the reported case, a review of the literature identified 9 previously reported cases of NK cell leukemia in patients 18 years of age or less. Cases were subdivided into blastic, acute/aggressive, and myeloid precursor NK cell leukemia based upon CD13/33 expression and morphologic characteristics. Compared to pediatric acute/aggressive NK cell leukemia, children with blastic NK cell leukemia showed greater variation in age and race. Prognosis was poor for all groups. Pediatric blastic NK cell leukemia is a distinct clinicopathologic entity which differs from other types of pediatric NK cell leukemia.
CARE‐ELICITING BEHAVIOR IN MAN

The concept of care-eliciting behavior is proposed as an essential part of the phenomenon of attachment. The origins of this behavior in man are examined in terms of both ontogenesis and phylogenesis. The relevance of the behavior for species advantage is considered. Finally, it is suggested that morbid manifestations of care-eliciting constitute a number of psychiatric disorders previously considered to be unrelated.
Effectiveness of Aquatic Exercises in Women With Rheumatoid Arthritis: A Randomized, Controlled, 16-Week Intervention—The HydRA Trial

Objective The purpose of this study was to compare the effectiveness of land-based (LB) and water-based (WB) aerobic exercises in women with rheumatoid arthritis (RA). Design A total of 133 women with RA were included in this randomized, blinded, prospective, 16-week controlled trial. The subjects were randomized into 3 groups: WB (n = 33), LB (n = 33), and control (n = 34). Muscle strength (MS) was measured using an isokinetic dynamometer. Disease activity (DAS-28) and functional ability (health assessment questionnaire) were measured by an expert rheumatologist. Total body densitometry was used to assess body composition. The intervention was performed 3 times per week, and all groups were evaluated at baseline and after 8 and 16 weeks. Compliance, concomitant medications, and adverse events were recorded. The data were analyzed by intention to treat. P < 0.05 was set as significant. Results Of the 133 patients recruited, 100 were randomized and 82 completed the study. In the first evaluation, the 3 groups were matched to age, body composition, functional capacity, MS, and concomitant medications. After 16 weeks, there were no significant changes of knee MS neither body composition among the groups. However, there was a significant improvement in disease activity and functional ability in the WB after 8 and 16 weeks. Conclusion Aquatic exercises provided significant improvement in disease activity, pain, and functional capacity.
Sorcin Inhibits Calcium Release and Modulates Excitation-Contraction Coupling in the Heart*

Activation of Ca2+ release channels/ryanodine receptors (RyR) by the inward Ca2+ current (ICa) gives rise to Ca2+-induced Ca2+ release (CICR), the amplifying Ca2+ signaling mechanism that triggers contraction of the heart. CICR, in theory, is a high-gain, self-regenerating process, but an unidentified mechanism stabilizes it in vivo. We reported previously (Lokuta, A. J., Meyers, M. B., Sander, P. R., Fishman, G. I., and Valdivia, H. H. (1997) J. Biol. Chem. 272, 25333–25338) that sorcin, a 22-kDa Ca2+-binding protein, binds to cardiac RyRs with high affinity and completely inhibits channel activity. Here we show that sorcin significantly inhibits both the spontaneous activity of RyRs in quiescent cells (visualized as Ca2+ sparks) and the ICa-triggered activity of RyRs that gives rise to [Ca2+]i transients. Because sorcin decreased the amplitude of the [Ca2+]i transient without affecting the amplitude or kinetics of ICa, the overall effect of sorcin was to reduce the “gain” of excitation-contraction coupling. Immunocytochemical staining shows that sorcin localizes to the dyadic space of ventricular cardiac myocytes. Ca2+ induces conformational changes and promotes translocation of sorcin between soluble and membranous compartments, but the [Ca2+] required for the latter process (ED50 = ∼200 μm) appears to be reached only within the dyadic space. Rapid injection of 5 μm sorcin onto the cytosolic face of RyRs reconstituted in lipid bilayers resulted in complete inhibition of channel activity in ≤ 20 ms. Thus, sorcin is a potent inhibitor of both spontaneous and ICa-triggered RyR activity and is kinetically capable of playing a role in terminating the positive feedback loop of CICR.
Remittances and Income Smoothing

Due to inadequate savings and binding borrowing constraints, income volatility can make households in developing countries particularly susceptible to economic hardship. We examine the role of remittances in either alleviating or increasing household income volatility using Mexican household level data over the 2000 through 2008 period. We correct for reverse causality and endogeneity and find that while income smoothing does not appear to be the main motive for sending remittances in a non-negligible share of households, remittances do indeed smooth household income on average. Other variables surrounding income volatility are also considered and evaluated.
Radiation-induced EGFR-signaling and control of DNA-damage repair

Purpose: Over the last decade evidence has accumulated indicating that cell membrane-bound growth factor receptor of the erbB family and especially the epidermal growth factor receptor EGFR (erbB1) mediates resistance of tumor cells to both chemo- and radiotherapy when mutated or overexpressed. More recently a novel link between EGFR signaling pathways and DNA repair mechanisms, especially non-homologous end joining (NHEJ) repair could be demonstrated. The following review summarizes the current knowledge on the role of EGFR and its downstream signaling pathways in the regulation of cellular radiation response and DNA repair. Conclusion: The novel findings on radiation-induced EGFR-signaling and its involvement in regulating DNA-double strand break repair need further investigations of the detailed mechanisms involved. The results to be obtained may not only improve our knowledge on basic mechanisms of radiation sensitivity/resistance but also will promote translational approaches to test new strategies for clinically applicable molecular targeting.
Studies on the bacterial component of soybean root nodules: cytology and organization in the host tissue.

Light- and electron-microscope studies of bacteroids in soybean nodule sections and suspensions of isolated bacteroids have shown well-defined nuclear elements, containing tangled filaments and dense granules. The cytoplasm was poorly stained as seen in the light microscope but had considerable dye-reducing activity localized at the poles, giving the appearance of granules. However, electron micrographs revealed no electron dense granules in the cytoplasm near the poles. Cell walls were not found on bacteroids in suspensions isolated from nodules, but were present on bacteria grown in vitro, and on bacteroids in the host tissue. Electron micrographs of thin sections of mature nitrogen-fixing nodules revealed a system of double membranes enclosing groups of four or six bacteroids. These membranes appeared to originate from the host cells and their development was followed in nodules aged from 1–5 weeks; they could be centrifugally separated from the bacteroid fraction of crushed nodules. The origin of the membrane system and its possible role in nodule functions is discussed.
Chromosomal gentamicin resistance transposon Tn3706 in Streptococcus agalactiae B128

Streptococcus agalactiae B128 is the only highly gentamicin-resistant group B streptococcal (GBS) strain described so far. This strain carries a chromosomal gentamicin resistance transposon, designated Tn3706, which is similar, if not identical, to the Tn4001 and Tn5281 transpons detected in Staphylococcus aureus and Enterococcus faecalis, respectively. Transposition of Tn3706 occurred onto the GBS plasmid pIP501 in two different loci of its 7.5-kb AvaII fragment carrying the genes for chloramphenicol and erythromycin resistance. Molecular analysis of pIP501 derivatives showed that Tn3706 is composed of a central fragment containing the aac6'-aph2" gene; this fragment is flanked by two tandemly repeated copies of IS256 at the 5' extremity of the resistance gene and a single inverted copy of IS256 at its 3' extremity. The two tandemly repeated copies of IS256 were separated by a 6-bp segment identical to that found, in the same orientation, in the IS256-aac6'-aph2" junction. The hybrid replicons pIP501::Tn3706 were found to be structurally unstable following conjugative transfer between GBS strains. Numerous individual copies of IS256 were detected in B128, but this insertion sequence was not found in the 11 wild-type, gentamicin-susceptible GBS strains studied.
The bronze baby syndrome: evidence of increased tissue concentration of copper porphyrins

A case regarding a newborn infant with severe Rh haemolytic disease, who presented with the bronze baby syndrome and eventually died, is reported. The postmortem examination showed marked extramedullary haematopoiesis in the liver and spleen, heavy hepatic haemosiderosis and mild intralobular cholestasis. The porphyrin content, which was assayed in different tissues. was very high in the liver, suggesting that the increased erythropoiesis seen in Rh haemolytic disease leads to an increased synthesis of porphyrins as by‐products of haem synthesis. Phototherapy causes photodestruction, sensitized by bilirubin, of porphyrins (mainly copper porphyrins), yielding brown photoproducts.
The Stimulatory Effects of Hofmeister Ions on the Activities of Neuronal Nitric-oxide Synthase

A variety of monovalent anions and cations were effective in stimulating both calcium ion/calmodulin (Ca2+/CaM)-independent NADPH-cytochrome creductase activity of, and Ca2+/CaM-dependent nitric oxide (NO⋅) synthesis by, neuronal nitric oxide synthase (nNOS). The efficacy of the ions in stimulating both activities could be correlated, in general, with their efficacy in precipitating or stabilizing certain proteins, an order referred to as the Hofmeister ion series. In the hemoglobin capture assay, used for measurement of NO⋅ production, apparent substrate inhibition byl-arginine was almost completely reversed by the addition of sodium perchlorate (NaClO4), one of the more effective protein-destabilizing agents tested. Examination of this phenomenon by the assay of l-arginine conversion tol-citrulline revealed that the stimulatory effect of NaClO4 on the reaction was observed only in the presence of oxyhemoglobin or superoxide anion (generated by xanthine and xanthine oxidase), both scavengers of NO⋅. Spectrophotometric examination of nNOS revealed that the addition of NaClO4 and a superoxide-generating system, but neither alone, prevented the increase of heme absorption at 436 nm, which has been attributed to the nitrosyl complex. The data are consistent with the release of autoinhibitory NO⋅ coordinated to the prosthetic group of nNOS, which, in conjunction with an NO⋅ scavenger, causes stimulation of the reaction.
Are renal proximal tubular epithelial cells constantly prepared for an emergency? Focus on "the proliferation capacity of the renal proximal tubule involves the bulk of differentiated epithelial cells".

a human kidney contains approximately one million functional units (the nephrons) that consist of a filter (the glomerulus) and a processing portion (the proximal, intermediate, and distal tubule). The glomeruli produce ∼180 liters of primary filtrate every day of which only 1 to 2 liters are
Measurement of Olfactory Signal Detectability Using an Air-Dilution Olfactometer

The Cheesman air dilution olfactometer, although designed for group threshold measurements, was modified to allow individual testing of subjects. However, adaptation effects of olfactory stimuli precluded use of interstimulus intervals of less than 30 sec. so that 3-hr. testing sessions were necessary to obtain a single measurement of sensitivity. Four subjects were tested intensively with isopropyl alcohol (CH3CH(OH)CH3) at concentration levels determined by previous group threshold studies. In the first condition, one concentration only was presented in testing sessions, while in the second condition, six concentrations were presented and the limits of concentrations adjusted to allow subthreshold presentations. Signal detectability indices (de') were calculated more frequently and more reliably in the second condition than in the first.
[Anatomopathological findings during development of diabetic cardiomyopathy in rats].

BACKGROUND The diabetic cardiomyopathy occurs in both type 1 and type 2 diabetes mellitus. Hyperglycemia and associated metabolic changes participate in the pathogenesis of this disease. OBJECTIVE To characterizes various pathological changes occurring during the development of diabetic cardiomyopathy in rats. METHODS Diabetic rats were used for streptozotocin administration. At 7, 14, 21 and 30 days after toxic administration, the heart was obtained and placed in a Hartman solution and 4% p-formaldehyde. Five-micrometer thick sections were stained with hematoxylin-eosin, Masson trichrome and immunocytochemistry using anti-β-tubulin antibody. RESULTS At 14 days after application of streptozotocin, dilated sinusoids with endothelial lining in the myocardium and collagen deposits in the cardiac interstitium and between the Purkinje fibers were observed. At 21 days there was a slight decrease of the arteriolar lumen due to hyperplasia of the medial layer. It is important to note that cardiac sinusoids as well as collagen deposits became more evident at 30 day of the study, as well as a major derangement of the microtubular system of the cardiomyocytes. CONCLUSIONS Cardiac sinusoids representing fetal vascular pattern and interstitial fibrosis in the myocardium and the microtubular derangement of cardiomyocytes support the fact that the pathophysiological mechanism of diabetic cardiomyopathy begins in the coronary microcirculation due to changes in cardiac metabolism, contributing to the development of myocardial dysfunction in diabetes.
A research note about military-civilian humanitarianism: more questions than answers.

'Military-civilian humanitarianism'--or the coming together of military forces and civilian aid agencies to deal with the human suffering from complex emergencies--has numerous forms, but disenchantment has resulted from the Somalia and Bosnia syndromes. There is little political will at present, but evidence from the immediate post-Cold War era suggests how multilateral military operations could expand or contract in future to the benefit or peril of war victims. Partly a literature review but more importantly a framework for interpreting recent publications, this essay seeks to move beyond exchanging assertions. There is a contextualisation of recent literature; a definition of military-civilian humanitarianism; a discussion of possible military contributions to humanitarian action; a framework to assess the effectiveness of military-civilian humanitarianism; and a preliminary analysis of experience from northern Iraq, Somalia, Bosnia, Rwanda and Haiti. Caveat lector: At this point in time, there are still 'more questions than answers'.
Jobs, working hours, and remuneration packages for migrants and urban residents

In this chapter we look at the working conditions and remuneration of migrants versus incumbent urban residents in China in the 2008 wave of the RUMiCI project. We find that the average hourly compensation for an urban worker is more than double that of migrants. Inequality of non-wage compensation is higher than that of hourly wages, mainly because urban workers are much more likely to benefit from various insurance schemes than migrants. Nearly three-quarters of the hourly compensation differences can be explained by observable characteristics. Returns to education and experience are lower for the migrants. They also have less education and accumulate less experience, perchance due to the temporary nature of the migration. We find strong differences between cities. For example, total compensation in Wuxi, Hefei, Ningbo and Chengdu is roughly the same for migrants as for the equivalent urban city dweller with the same characteristics. This equal treatment is also reflected in non-wage remuneration components. Yet in Chongqing and several other cities, a migrant is paid less than half the equivalent urban city dweller. This suggests that some cities ‘compete’ for migrants whilst others do not, and it also suggests that there are many city dwellers who would be better off if they move to other cities.