Miracle-dz/UniFAR-FTUs huggingface dataset:
The Prediction of Gender and Attachment Styles on Shame, Guilt, and Loneliness*

Th e purpose of this study is to examine the predictive power of attachment styles and gender on negative social emotions such as shame, guilt, and loneliness. Th e sample consists of 360 (183 female, 177 male) students attending to diff erent departments of Marmara University. Th e Relationships Questionnaire, Guilt-Shame Scale, and UCLA Loneliness Scale were used as instruments. Results obtained from hierarchical regression analysis showed that gender has a predictive power on shame, solely. When the predictivity of attachment styles on negative social emotions was examined, the results revealed that shame was predicted by secure and dismissing attachment style, whereas guilt was predicted by only dismissing attachment. Furthermore, all attachment styles played a determining role on loneliness.
Wealth and Consumption: French Households in the Crisis

Relying on an original household survey (PATER survey), we document how the 2008–9 crisis affected households’ wealth, expectations, and consumption plans in France. We then show that households experiencing losses relating to their housing or their financial wealth were more likely to change their plans by reducing consumption expenditure. Moreover, our results suggest a certain degree of heterogeneity in consumption reaction across individuals depending on their level of wealth, on the composition of their consumption basket, and on the type of shocks experienced (gains/losses). Besides the direct wealth effect, our results also provide evidence of the role played by changes in expectations on consumption plans (confidence channel).
GASTROINTESTINAL , HEPATOBILIARY , AND PANCREATIC PATHOLOGY Cytoglobin De fi ciency Promotes Liver Cancer Development from Hepatosteatosis through Activation of the Oxidative Stress Pathway

opyright a 2015 American Society for Inve ublished by Elsevier Inc. All rights reserved ttp://dx.doi. org/10.1016/j.ajpath. 2014.12. 017 This study was conducted to clarify the role of cytoglobin (Cygb), a globin expressed in hepatic stellate cells (HSCs), in the development of liver fibrosis and cancer in nonalcoholic steatohepatitis (NASH). Cygb expression was assessed in patients with NASH and hepatocellular carcinoma. Mouse NASH model was generated in Cygb-deficient (Cygb / ) or wild-type (WT) mice by giving a choline-deficient amino acidedefined diet and, in some of them, macrophage deletion and N-acetyl cysteine treatment were used. Primary-cultured mouse HSCs isolated from WT (HSCs ) or Cygb / (HSCs ) mice were characterized. As results, the expression of CYGB was reduced in patients with NASH and hepatocellular carcinoma. Choline-deficient amino acid treatment for 8 weeks induced prominent inflammation and fibrosis in Cygb / mice, which was inhibited by macrophage deletion. Surprisingly, at 32 weeks, despite no tumor formation in the WT mice, all Cygb / mice developed liver cancer, which was ameliorated by N-acetyl cysteine treatment. Altered expression of 31 genes involved in the metabolism of reactive oxygen species was notable in Cygb / mice. Both HSCs null and Cygb siRNA-transfectedHSCs wild exhibited the preactivation condition. Our findings provide important insights into the role that Cygb, expressed in HSCs during liver fibrosis, plays in cancer development with NASH. (Am J Pathol 2015, 185: 1045e1060; http://dx.doi.org/10.1016/j.ajpath.2014.12.017)
Factors Important to Personalizing Therapy for Preventing and Treating Metastatic Disease Semipersonalized Medicine

CME Accreditation Statement: This activity (“ASIP 2013 AJP CME Program in Pathogenesis”) has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Society for Clinical Pathology (ASCP) and the American Society for Investigative Pathology (ASIP). ASCP is accredited by the ACCME to provide continuing medical education for physicians.
PDFlib PLOP: PDF Linearization, Optimization, Protection Page inserted by evaluation version

This study introduces a novel, simplified method for the evaluation of murine intestinal transit and contractility using fluorescence and video imaging. Intestinal transit was measured by evaluating the intestinal distribution of non-absorbable fluoresceinlabelled dextran (70 kDa, FD70) along the gastrointestinal (GI) tract. After excision of the GI tract, two full-field images – one in normal illumination mode and another in fluorescent mode – were taken with a charge coupled device (CCD) camera and subsequently matched for calculation of fluorescence distribution along the GI tract. Immediately after, intestinal contractility was evaluated in different regions of the intact intestine by spatiotemporal motility mapping (i.e. video imaging). In control mice, the small intestine showed vigorous oscillatory contractions and FD70 was primarily distributed within the terminal ileum/caecum at 90 min postgavage. As validation step, the effect of intestinal manipulation (IM, surgical procedure) and two pharmacological agents – known to alter GI motility – was tested. At 24 h postoperatively, spontaneous contractile activity of the small intestine was nearly abolished in IM mice, leaving the small intestine distended and resulting in a significantly delayed intestinal transit. In accordance, spontaneous mechanical activity of circular muscle strips in standard organ baths was significantly reduced in IM mice compared to control mice. Administration of atropine (1–3 mg kg, i.p.) suppressed spontaneous contractile activity along the entire intestinal tract and induced a dose-related delay in intestinal transit. In contrast, metoclopramide (3–10 mg kg, i.p.) markedly increased contractile activity – however only in the upper GI tract – and accelerated intestinal transit in a dose-
Cultural Differences in the Environmental Worldview of Children

Normal 0 21 false false false TR X-NONE X-NONE The New Ecological Paradigm (NEP) is a popular measure of environmental concern and pro-environmental orientation of adults, which has recently been modified for use with children. For this paper, we have collected questionnaires from 1586 children from three different countries and continents (i.e. Zimbabwe, Belgium and Vietnam). In this paper we will present the NEP-scores and the search for dimensionality of the scales, across the different populations, by means of factor analyses. The results indicate that there is a clear and highly significant cultural influence on the environmental worldview of children, when developed and developing countries are compared. Such differences are important for those designing and evaluating environmental education initiatives because such initiatives need to be rooted in the local specific situation – both physically and attitudinally. Normal 0 21 false false false TR X-NONE X-NONE Keywords: Environmental worldview; new ecological paradigm; NEP scale for children; cross-cultural differences
Temporal variations of atomic oxygen in the upper mesosphere from SABER

[1] One of the atmospheric constituents that can be retrieved from observations by the Sounding of the Atmosphere using Broadband Emission Radiometry (SABER) instrument on the Thermosphere-Ionosphere-Mesosphere Energetics and Dynamics (TIMED) satellite is atomic oxygen in the upper mesosphere. Atomic oxygen can be determined during both day and night using two different techniques that both rely on ozone chemistry. The O concentrations retrieved from SABER data are higher by a factor of 2–5 compared to concentrations determined from other measurements and techniques and compiled in current empirical models. This paper presents variability of atomic oxygen with a focus on the diurnal cycle in low latitudes and the seasonal cycle of daily mean atomic oxygen globally. The results show a large diurnal variation, ranging from a factor of 2 to more than a factor of 10, of atomic oxygen near the equator. The relative magnitude varies with season (larger near the equinoxes) and with altitude (largest near 85 km). Vertical transport by the migrating diurnal tide explains the observed variation. The semiannual variation in tidal amplitude affects the seasonal variation of daily average atomic oxygen, which likely indicates that there is irreversible transport by the tides. At high latitudes, the atomic oxygen variation is characterized by wintertime maxima over the altitude range 80–95 km and summertime maxima above. The wintertime peaks are associated with the downwelling from the mean circulation and are particularly strong in late winter of 2004, 2006, and 2009, responding to the unusual dynamical situations in those years.
Immigrant Status and Secondary School Performance as Determinants of Post-Secondary Participation: A Comparison of Canada and Switzerland. OECD Education Working Papers, No. 77.

This working paper seeks to explore the reasons why educational attainment in the immigrant population varies between North America and Europe. Specifically, the examples of Canada and Switzerland are used as Canada has an immigrant population with a typically higher rate of post-secondary education than that of the domestic population, while in Switzerland the opposite is true. Analysis shows that while differences in immigration policy play a significant role, there are many other variables which affect educational attainment in immigrants, such as the education level of the parents, source region and home language. Le present document de travail tente d’explorer les raisons pour lesquelles le niveau de formation de la population immigree varie entre l’Amerique du Nord et l’Europe. Il s’attache plus particulierement aux exemples du Canada et de la Suisse, les diplomes de l’enseignement post-secondaire etant typiquement plus nombreux dans la population immigree que dans la population autochtone au Canada, tandis qu’en Suisse, c’est l’inverse qui s’observe. L’analyse montre que si les differences en termes de politiques d’immigration jouent un role important, il existe egalement de nombreuses autres variables qui influent sur le niveau de formation de la population immigree, telles que le niveau de formation des parents, la region d’origine et la langue parlee a la maison.
Agrobacterium strains isolated from root nodulesof commonbean speci ¢ cally reducenodulation byRhizobiumgallicum

In a previous work, we showed that non-nodulating agrobacteria strains were able to colonize root nodules of common bean. Both rhizobia and agrobacteria coexisted in the infected nodules. No impact on symbiosis was found in laboratory conditions when using sterile gravel as a support for growth. In this study, soil samples originating from different geographic and agronomic regions in Tunisia were inoculated with a mixture of agrobacteria strains isolated previously from root nodules of common bean. A significant effect on nodulation and vegetal growth of common bean was observed. Characterization of nodulating rhizobia and comparison with non-inoculated controls showed a biased genetic structure. It seemed that Rhizobium gallicum was highly inhibited, whereas nodulation by Sinorhizobium medicae was favored. Co-inoculation of non-sterile soils with R. gallicum and agrobacteria confirmed these findings. In vitro antibiosis assays indicated that agrobacteria exercised a significant antagonism against R. gallicum.
Biomimetic synthesis of monodisperse rosette-like calcite mesocrystals regulated by carboxymethyl cellulose and the proposed mechanism : An unconventional rhombohedra-stacking route

Carboxymethyl cellulose (CMC) is systematically investigated for the first time in regulating the CaCO3crystallization using a biomimetic gas-diffusion method. Monodisperse rosette-like calcite spherules in uniform size with their surfaces composed of rhombohedral subunits were synthesized in certain conditions. According to time-resolved experiment, the evolution of the crystal morphology was traced and the possible route in which rosette-like spherules form is suggested. We propose that the amorphous calcium carbonate precursors form initially and act as secondary nuclei, followed by the stacking of rhombohedral subunits in partial rather than complete superposition between each other due to the electrostatic repulsive interactions between the polyanion chains adsorbed on the blocks, which results in the final rosette-like morphology. Mineralization experiments in CMC solutions with different concentrations were also carried out and the results obtained at no higher than 1 g L−1 further prove the above mechanism from the fact that the extent of the polymer influence decreases proportionally with concentration, i.e. the degree of superposition of the building blocks becomes larger by decreasing the CMC concentration. In contrast, in a higher polymer concentration of 5 g L−1, another aggregation way from nanoparticles is adopted. In addition, the influence of the initial calcium ion concentration and the chain length of CMC on the crystal morphology were also investigated. The present investigation on the influence of CMC on CaCO3crystallization not only provides for the formation mechanisms of the rosette-like calcite spherules but also leads to a new possible route to fabricate new materials which can be used in many industrial areas.
On the coexistence of stellar-mass and intermediate-mass black holes in globular clusters

In this paper, we address the question: What is the probability of stellar-mass black hole (BH) binaries co-existing in a globular cluster with an intermediate-mass black hole (IMBH)? Our results suggest that the detection of one or more BH binaries can strongly constrain the presence of an IMBH in most Galactic globular clusters. More specifically, the detection of one or more BH binaries could strongly indicate against the presence of an IMBH more massive than & 10 3 M⊙ in roughly 80% of the clusters in our sample. To illustrate this, we use a combination of N-body simulations and analytic methods to weigh the rate of formation of BH binaries against their ejection and/or disruption rate via strong gravitational interactions with the central (most) massive BH. The eventual fate of a sub-population of stellar-mass BHs (with or without binary companions) is for all BHs to be ejected from the cluster by the central IMBH, leaving only the most massive stellar-mass BH behind to form a close binary with the IMBH. During each phase of evolution, we discuss the rate of inspiral of the central BH-BH pair as a function of both the properties of the binary and its host cluster.
The impact of liquidity on senior credit

This paper examines the effects of liquidity during the 2007–09 crisis, focussing on the Senior Tranche of the CDX.NA. IG Index and on Moody’s AAA Corporate Bond Index. It aims to understand whether the sharp increase in the credit spreads of these AAArated credit indices can be explained by worse credit fundamentals alone or whether it also reflects a lack of depth in the relevant markets, the scarcity of risk-capital, and the liquidity preference exhibited by investors. Using cointegration analysis and error correction models, the paper shows that during the crisis lower market and funding liquidity are important drivers of the increase in the credit spread of the AAA-rated structured product, while they are less significant in explaining credit spread changes for a portfolio of unstructured credit instruments. Looking at the experience of the subprime crisis, the study shows that when the conditions under which securitisation can work properly (liquidity, transparency and tradability) suddenly disappear, investors are left highly exposed to systemic risk.
Experiential marketing, customer satisfaction, behavioral intention: timezone game center surabaya

Experience Economy now affects the progression of economics and customer value will increase whether companies offer memorable experiences. Experiential Marketing focuses on customer experiences from sense, feel, think, act and relate experiences, therefore called customers as affective decision makers. There is a lack of research on emotional response of service companies, and this research is directed to fill in the gap. Research aims to analyze the effect of experiential marketing on customer satisfaction, the effect of experiential marketing on behavioral intention, and the effect of customer satisfaction on behavioral intention at Time zone game center Surabaya. Data is analyzed by structural equation modeling (SEM) with AMOS 4.0. The results show that hypothesis one is accepted, experiential marketing affects customer satisfaction at Time zone, hypothesis two is also accepted, experiential marketing affects behavioral intention of Time zone's customer, but hypothesis three is rejected, customer satisfaction do not affect behavioral intention at Time zone game center Surabaya.
Leaf form-climate relationships on the global stage: an ensemble of characters

Aim Early in their evolution, angiosperms evolved a diversity of leaf form far greater than that of any other group of land plants. Some of this diversity evolved in response to varying climate. Our aim is to test the global relationship between leaf form in woody dicot angiosperms and the climate in which they live.
Effect of Organic Farming on Nutrient Uptake and Quality of Potato

The experiment was carried out at the Environmental Science Field Laboratory, Bangladesh Agricultural University, Mymensingh during the period November 2004 to February 2005 to evaluate the effect of organic farming on soil and potato quality. The experiment was laid out in a randomized complete Block Design with five treatment and three replications. The treatments and their combinations were cowdung, poultry manure, inorganic fertilizer, cowdung plus inorganic fertilizer and poultry manure plus inorganic fertilizer. The nutrient content of P, K, Ca, Mg, Zn of tuber and haulm, and starch and protein content in tuber were highest in cowdung treated potato and but N and S content of both tuber and haulm were highest in case of poultry manure. The uptake of P, K, Mg and S of both tuber and haulm in case of poultry manure but N and Zn uptake was highest in case of poultry manure plus inorganic fertilizer. Finally, calcium uptake was highest in cowdung in both cases of tuber and protean and starch contents were influenced by organic farming. DOI: http://dx.doi. org/10.3329/jesnr.v5i2. 14818 J. Environ. Sci. & Natural Resources, 5(2): 219-224 2012
Dovepress Open Access to Scientific and Medical Research Open Access Full Text Article Her2 Breast Cancer Therapies: a Review in Order To

Amplification of the HER2 gene and/or overexpression of its protein product have been found in up to 25% to 30% of human breast cancers and have been shown to be associated with poorer outcomes compared to 'HER2 normal' breast cancer. Research has focused on developing therapies directed to the HER2 receptor and its pathway. These include the monoclonal antibody trastuzumab, which has improved outcomes when used in patients with both advanced and early breast cancer. Lapatinib is a small-molecule tyrosine kinase inhibitor which has demonstrated activity in advanced breast cancer and is currently being evaluated in early stage disease. We discuss the therapeutic rationale and clinical trial experience with these agents. Other novel and emerging strategies targeting the HER2 receptor and its pathway are also discussed. These strategies include novel HER2 antibodies and small-molecule inhibitors, antibody–drug conjugates, agents targeting downstream components of the HER2 signaling pathway, and heat shock protein 90 (HSP90) inhibitors. The human epidermal growth factor receptor 2 (HER2) gene, also known as c-erbB2 and neu, encodes a 185-kDa transmembrane glycoprotein receptor. This receptor belongs to the ErbB family of growth factor receptors with intrinsic tyrosine kinase activity, the members of which exist in homodimer and heterodimer form when activated. 1 Other members of the ErbB family are the epidermal growth factor receptor 1 (EGFR/HER1), HER3 and HER4. Amplification of the HER2 gene and/or overexpression of its protein product have been found in up to 25% to 30% of human breast cancers 2,3 and have been shown to be associated with poorer prognosis on multi-variate analyses. In an effort to improve the outcomes of patients with HER2 positive (HER2+) breast cancer, research has focused on developing therapies directed to the HER2 receptor and its pathway. These therapies, which include the monoclonal anti-body trastuzumab and the small molecule tyrosine kinase inhibitor lapatinib, as well as other novel and emerging strategies, will be discussed in this review. The mechanisms of action of the therapies discussed in this review are summarized in Table 1. Trastuzumab The initial HER2 targeting antibody was a murine monoclonal antibody targeting the extracellular domain IV of the receptor (muMAb 4D5), derived by immunizing mice with cells that expressed high levels of the HER2 protein product.
Feeding Relations of the Atlantic Silverside Menidia menidia in the Minas Basin, Bay of Fundy

Feeding habits of the Atlantic silverside Menidia menidia were studied from June to November 1979. Analysis of gut fullness with respect to tidal state suggests that feeding occurs on ebb tide and not during flooding tide. It is suggested that extrtm~ne turbidity prevents feeding on the rising tide. The major prey of larvae and early juveniles was Euryternora herdmani; larger silversides ( > l 0 0 mm) fed more heavily upon Corophiurn volutator, Diastylis polita, Crangon septernspinosa, various isopods and insects. These benthic organisms may bc mdde more accessible to the silverside by tidal turbulence causing resuspension of the sediments and benthos during the flooding tide. Tiderelated movements of M. rnenidia result in maxlmum utilization of these periodically available food resources.
What Gives Rise to the Neural Signals of Episodic Memory ?

The neural pattern similarity during encoding, which reflects the fidelity of neural representations and studyphase pattern reinstatement, is predictive of later subsequent memory. A fundamental question of human episodic memory concerns the cognitive and neural representations and processes that give rise to the neural signals of memory. By integrating behavioral tests, formal computational models, and neural measures of brain activity patterns, recent studies suggest that memory signals not only depend on the neural processes and representations during encodingandretrieval,butalsoonthe interactionbetweenencodingandretrieval (e.g., transfer-appropriate processing), as well as on the interaction between the tested events and all other events in the episodic memory space (e.g., global matching). In addition,memory signals are also influencedby the compatibility of the event with the existing long-term knowledge (e.g., schemamatching). These studies highlight the interactive nature of human episodic memory. Episodic memory performance is linked to neural pattern reinstatement during retrieval, which is related to hippocampal activation and is affected by the extent of cue overlap between encoding and retrieval.