Miracle-dz/UniFAR-FTUs huggingface dataset:
Exploring the Effectiveness of Immersive Video for Training Decision-Making Capability in Elite, Youth Basketball Players

Decision-making is an essential capability for success in team sport athletes. Good decision-making is underpinned by perceptual-cognitive skills that allow athletes to assess the environment and choose the correct choice from a number of alternatives. Previous research has demonstrated that decision-making can be trained “off-line” by exposing athletes to gameplay scenarios and having them make decisions based on the information presented to them. These scenarios are typically presented on television monitors or using life-size projections but recent advances in immersive video capabilities provide opportunities to improve the fidelity of training by presenting a realistic, 360° view of the competition environment. The purpose of this study was to assess the effectiveness of immersive video training and whether training would improve decision-making performance in elite, youth basketball players (male and female). A training group completed 10 or 12 immersive video (360° video presented in a head-mounted display) training sessions in which they viewed and responded to gameplay scenarios across 3-weeks while the control group only participated in their usual training routine. Performance was assessed on an immersive video test and during small-sided games (SSG). The male training group had a large, non-significant improvement on immersive test score (+4.0 points) and in the SSG (+5.8 points) compared to the male control group (+0.3 points and +1.0 points, respectively). While both the female control group (+9.7 points) and training group (7.4 points) had large improvements in the immersive training test, only the female control improved their performance in the SSG (+6.9 points). Despite the mixed findings, there may be benefit for using immersive video for training decision-making skill in team sports. The implications of these findings (e.g., gender of the actors used to create stimuli, variety of scenarios presented) and the limitations of the experiment are discussed.
ANALISIS GERAK DASAR ANAK USIA 6-7 TAHUN

This study aims to know the students’ fundamental movement ability and to analyze those movements based on gender. It was conducted in SDN 1 Lemahabang Kulon, Cirebon Regency. The subject involved in this study was 24 students of the lower-primary levels in the school whose ages between 6-7 years old. Data collection method applied was the observation of the students’ fundamental movements. The assessment form on fundamental movement (Gallahue :1996) was used as the instrument of the study. The data was analyzed using a descriptive quantitative technique with a percentage. The finding shows that it was only 65.6 % students who properly mastered the fundamental movement of stability. Meanwhile, the fundamental movements of locomotor and manipulative were mastered only by 43 % and 41.7 %. Based on the gender analysis, the male students were better on fundamental movements than the female ones. To facilitate the future success of movement on students, it is suggested to have a directional and specific program on movement development. Keywords:, Early childhood, Fundamental movement Penelitian ini bertujuan untuk mengetahui kemampuan gerak dasar siswa serta menganalisa gerakan tersebut berdasarkan gender. Penelitian ini dilakukan di SDN 1 Lemahabang Kulon Kabupaten Cirebon. Subyek yang terlibat dalam penelitian adalah siswa sekolah dasar kelas rendah yang berusia 6-7 tahun yang berjumlah 24 anak. Pengumpulan data dalam penelitian ini menggunakan kegiatan observasi terhadap gerakan dasar siswa. Instrumen yang digunakan adalah format penilaian gerak dasar. Analisis data yang digunakan adalah deskriptif kuantitatif dengan menggunakan persentase. Hasil penelitian menunjukkan bahwa hanya 65.6% siswa yang menguasai dengan baik gerak dasar non-lokomotor. Sedangkan gerak dasar lokomotor dan manipulatif hanya 43% dan 41.7%. Berdasarkan analisis gender, siswa laki-laki memiliki kemampuan gerak dasar yang lebih baik daripada siswa perempuan. Untuk mendukung kesuksesan gerak siswa di masa mendatang, diperlukan program pengembangan gerak yang terarah dan spesifik. Kata Kunci: Anak usia dini, Gerak dasar
Flexible Graphene Field-Effect Transistors With Extrinsic  ${f}_{{{\mathrm{max}}}}$  of 28 GHz

Graphene field-effect transistors (G-FETs) on flexible substrates have demonstrated much higher strain limits than that on rigid substrates. In this letter, G-FETs with an extrinsic <inline-formula> <tex-math notation="LaTeX">${f}_{\textrm {max}}$ </tex-math></inline-formula> of 28 GHz on flexible polyethylene terephthalate (PET) substrates are presented. Polyimide film benzocyclobutene with 50-nm thickness is coated on a PET substrate surface for optimizing the carrier transport. The results show that the hole mobility can reach up to 1738 cm<sup>2</sup>/V.s. An Au-supported graphene transfer technology is used to facilitate the quality of graphene in G-FETs and reduce the output parasitic resistance to <inline-formula> <tex-math notation="LaTeX">$50~\Omega $ </tex-math></inline-formula>. The measured figure of metric of “<inline-formula> <tex-math notation="LaTeX">${f}_{\textrm {max}}\cdot {L}_{\textrm {g}}$ </tex-math></inline-formula>” is <inline-formula> <tex-math notation="LaTeX">$8.4~\textrm {GHz}\cdot \mu \text{m}$ </tex-math></inline-formula>, which is 105% higher than the highest reported results on polymeric substrates. The RF performance of flexible G-FETs under the bending condition is also studied. The results of the letter will be useful for developing the millimeter-wave flexible graphene integrated circuits.
Endoparasites of Jungle Cats (Felis chaus) and Their Pathologic Lesions

Background: The jungle cats (Felis chaus) are native to Asia, and found in Iran. Although north of Iran has a wide distribution of jungle cats, there is not any data about prevalence of parasitic infections in the population of these cats. Methods: From 2012 to 2015, seven specimens of the wild jungle cat (Felis chaus) from north of Iran, Mazandaran Province, northern Iran were collected and examined for their endoparasites and pathological lesions which were caused by the parasites. Results: Parasitological evaluations showed several species of endoparasites in the small intestine of cats including nematode (Toxocara cati), trematode (Alaria alata), and cestode (Mesocestoides lineatus). All of the examined jungle cats were infected to parasitic infections. From the total number of 7 jungle cats T. cati was found in 6 cats, A. alata in 1 cat, and M. lineatus was recovered from 3 cats. Histopathological samples displayed necrosis, vacuolar degeneration, atrophy, destruction of tissue, hyperemia, and infiltration of inflammatory cells in the intestine tissue. Conclusion: This study for the first reported T. cati, A. alata, and M. lineatus and their pathologic effects in the small intestine of jungle cat.
The Dépistage Cognitif de Québec: A New Clinician’s Tool for Early Recognition of Atypical Dementia

Introduction: Early recognition of atypical dementia remains challenging partly because of lack of cognitive screening instruments precisely tailored for this purpose. Methods: We assessed the validity and reliability of the Dépistage Cognitif de Québec (DCQ; www.dcqtest.org), a newly developed cognitive screening test, to detect atypical dementia using a multicenter cohort of 628 participants. Sensitivity and specificity were compared to the Montreal Cognitive Assessment (MoCA). A predictive diagnostic algorithm for atypical dementia was determined using classification tree analysis. Results: The DCQ showed excellent psychometric properties. It was significantly more accurate than the MoCA to detect atypical dementia. All correlations between DCQ indexes and standard neuropsychological measures were significant. A statistical model distinguished typical from atypical dementia with a predictive power of 79%. Discussion: The DCQ is a better tool to detect atypical dementia than standard cognitive screening tests. Expanding the clinician’s tool kit with the DCQ could reduce missed/delayed identification of atypical dementia and accelerate therapeutic intervention.
hnRNP Q Regulates Internal Ribosome Entry Site-Mediated fmr1 Translation in Neurons

Fragile X syndrome (FXS) caused by loss of fragile X mental retardation protein (FMRP), is the most common cause of inherited intellectual disability. Numerous studies show that FMRP is an RNA binding protein that regulates translation of its binding targets and plays key roles in neuronal functions. ABSTRACT Fragile X syndrome (FXS) caused by loss of fragile X mental retardation protein (FMRP), is the most common cause of inherited intellectual disability. Numerous studies show that FMRP is an RNA binding protein that regulates translation of its binding targets and plays key roles in neuronal functions. However, the regulatory mechanism for FMRP expression is incompletely understood. Conflicting results regarding internal ribosome entry site (IRES)-mediated fmr1 translation have been reported. Here, we unambiguously demonstrate that the fmr1 gene, which encodes FMRP, exploits both IRES-mediated translation and canonical cap-dependent translation. Furthermore, we find that heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) acts as an IRES-transacting factor (ITAF) for IRES-mediated fmr1 translation in neurons. We also show that semaphorin 3A (Sema3A)-induced axonal growth cone collapse is due to upregulation of hnRNP Q and subsequent IRES-mediated expression of FMRP. These data elucidate the regulatory mechanism of FMRP expression and its role in axonal growth cone collapse.
Background Subtraction With Real-Time Semantic Segmentation

Accurate and fast foreground (FG) object extraction is very important for object tracking and recognition in video surveillance. Although many background subtraction (BGS) methods have been proposed in the recent past, it is still regarded as a tough problem due to the variety of challenging situations that occur in real-world scenarios. In this paper, we explore this problem from a new perspective and propose a novel BGS framework with the real-time semantic segmentation. Our proposed framework consists of two components, a traditional BGS segmenter <inline-formula> <tex-math notation="LaTeX">$\mathcal {B}$ </tex-math></inline-formula> and a real-time semantic segmenter <inline-formula> <tex-math notation="LaTeX">$\mathcal {S}$ </tex-math></inline-formula>. The BGS segmenter <inline-formula> <tex-math notation="LaTeX">$\mathcal {B}$ </tex-math></inline-formula> aims to construct background (BG) models and segments FG objects. The real-time semantic segmenter <inline-formula> <tex-math notation="LaTeX">$\mathcal {S}$ </tex-math></inline-formula> is used to refine the FG segmentation outputs as feedbacks for improving the model updating accuracy. <inline-formula> <tex-math notation="LaTeX">$\mathcal {B}$ </tex-math></inline-formula> and <inline-formula> <tex-math notation="LaTeX">$\mathcal {S}$ </tex-math></inline-formula> work in parallel on two threads. For each input frame <inline-formula> <tex-math notation="LaTeX">$I_{t}$ </tex-math></inline-formula>, the BGS segmenter <inline-formula> <tex-math notation="LaTeX">$\mathcal {B}$ </tex-math></inline-formula> computes a preliminary FG/BG mask <inline-formula> <tex-math notation="LaTeX">$B_{t}$ </tex-math></inline-formula>. At the same time, the real-time semantic segmenter <inline-formula> <tex-math notation="LaTeX">$\mathcal {S}$ </tex-math></inline-formula> extracts the object-level semantics <inline-formula> <tex-math notation="LaTeX">${S}_{t}$ </tex-math></inline-formula>. Then, some specific rules are applied on <inline-formula> <tex-math notation="LaTeX">${B}_{t}$ </tex-math></inline-formula> and <inline-formula> <tex-math notation="LaTeX">${S}_{t}$ </tex-math></inline-formula> to generate the final detection <inline-formula> <tex-math notation="LaTeX">${D}_{t}$ </tex-math></inline-formula>. Finally, the refined FG/BG mask <inline-formula> <tex-math notation="LaTeX">${D}_{t}$ </tex-math></inline-formula> is fed back to update the BG model. The comprehensive experiments evaluated on the CDnet 2014 dataset demonstrate that our proposed method achieves the state-of-the-art performance among all unsupervised BGS methods while operating at the real-time and even performs better than some deep learning-based supervised algorithms. In addition, our proposed framework is very flexible and has the potential for generalization.
Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies

ABSTRACT Background High dietary intake or blood concentrations (as biomarkers of dietary intake) of vitamin C, carotenoids, and vitamin E have been associated with reduced risk of cardiovascular disease, cancer, and mortality, but these associations have not been systematically assessed. Objective We conducted a systematic review and meta-analysis of prospective studies of dietary intake and blood concentrations of vitamin C, carotenoids, and vitamin E in relation to these outcomes. Design We searched PubMed and Embase up to 14 February 2018. Summary RRs and 95% CIs were calculated with the use of random-effects models. Results Sixty-nine prospective studies (99 publications) were included. The summary RR per 100-mg/d increment of dietary vitamin C intake was 0.88 (95% CI: 0.79, 0.98, I2 = 65%, n = 11) for coronary heart disease, 0.92 (95% CI: 0.87, 0.98, I2 = 68%, n = 12) for stroke, 0.89 (95% CI: 0.85, 0.94, I2 = 27%, n = 10) for cardiovascular disease, 0.93 (95% CI: 0.87, 0.99, I2 = 46%, n = 8) for total cancer, and 0.89 (95% CI: 0.85, 0.94, I2 = 80%, n = 14) for all-cause mortality. Corresponding RRs per 50-μmol/L increase in blood concentrations of vitamin C were 0.74 (95% CI: 0.65, 0.83, I2 = 0%, n = 4), 0.70 (95% CI: 0.61, 0.81, I2 = 0%, n = 4), 0.76 (95% CI: 0.65, 0.87, I2 = 56%, n = 6), 0.74 (95% CI: 0.66, 0.82, I2 = 0%, n = 5), and 0.72 (95% CI: 0.66, 0.79, I2 = 0%, n = 8). Dietary intake and/or blood concentrations of carotenoids (total, β-carotene, α-carotene, β-cryptoxanthin, lycopene) and α-tocopherol, but not dietary vitamin E, were similarly inversely associated with coronary heart disease, stroke, cardiovascular disease, cancer, and/or all-cause mortality. Conclusions Higher dietary intake and/or blood concentrations of vitamin C, carotenoids, and α-tocopherol (as markers of fruit and vegetable intake) were associated with reduced risk of cardiovascular disease, total cancer, and all-cause mortality. These results support recommendations to increase fruit and vegetable intake, but not antioxidant supplement use, for chronic disease prevention.
Deep Features and Data Reduction for Classification of SD-OCT Images: Application to Diabetic Macular Edema

Diabetic Macular Edema (DME) is defined as the accumulation of extracellular fluids in the macular region of the eye, caused by Diabetic Retinopathy (DR) that will lead to irreversible vision loss if left untreated. This paper presents the use of a pre-trained Convolutional Neural Network (CNN) based model for the classification of Spectral Domain Optical Coherence Tomography (SD- OCT) images of Diabetic Macular Edema (DME) with feature reduction using Principal Component Analysis (PCA) and Bag of Words (BoW). The model is trained using SD-OCT dataset retrieved from the Singapore Eye Research Institute (SERI) and is evaluated using an 8-fold cross validation at the slide level and two patient leave out at the volume level. For the volume level, an accuracy of 96.88% is obtained for data that was preprocessed.
Parkinson's disease and multiple system atrophy have distinct α-synuclein seed characteristics

Parkinson's disease (PD) and multiple system atrophy (MSA) are distinct clinical syndromes characterized by the pathological accumulation of α-synuclein (α-syn) protein fibrils in neurons and glial cells. These disorders and other neurodegenerative diseases may progress via prion-like mechanisms. The prion model of propagation predicts the existence of “strains” that link pathological aggregate structure and neuropathology. Prion strains are aggregated conformers that stably propagate in vivo and cause disease with defined incubation times and patterns of neuropathology. Indeed, tau prions have been well defined, and research suggests that both α-syn and β-amyloid may also form strains. However, there is a lack of studies characterizing PD- versus MSA-derived α-syn strains or demonstrating stable propagation of these unique conformers between cells or animals. To fill this gap, we used an assay based on FRET that exploits a HEK293T “biosensor” cell line stably expressing α-syn (A53T)-CFP/YFP fusion proteins to detect α-syn seeds in brain extracts from PD and MSA patients. Both soluble and insoluble fractions of MSA extracts had robust seeding activity, whereas only the insoluble fractions of PD extracts displayed seeding activity. The morphology of MSA-seeded inclusions differed from PD-seeded inclusions. These differences persisted upon propagation of aggregation to second-generation biosensor cells. We conclude that PD and MSA feature α-syn conformers with very distinct biochemical properties that can be transmitted to α-syn monomers in a cell system. These findings are consistent with the idea that distinct α-syn strains underlie PD and MSA and offer possible directions for synucleinopathy diagnosis.
Life style habits, biochemical factors and their interaction in the prediction of incident hypertension during 21-year follow-up

Abstract Background: Hypertension is a global health threat and major cardiovascular risk. Various risk-prediction models for incident hypertension have been developed but not many of them have studied the risk-predictive value of life style factors in combination with cardiovascular biomarkers during long-term period of over 10 years. Methods: We examined differences in several classical variables for 299 subjects in OPERA (Oulu Project Elucidating Risk of Atherosclerosis) cohort in subjects with no or new hypertension during a follow-up period of 21 years. Effect of both various life style habits and biomarkers were investigated. Results: Baseline blood pressure, being overweight and smoking actively were independent predictors of new hypertension in majority of multivariate models during long-term follow-up of 21 years in subjects without previous hypertension. Increased high-sensitive C-reactive protein (hsCRP) level (> 3 mg/L) was the strongest predictor of incident hypertension in univariate model. Subjects with two or all three of main risk factors (being overweight, smoking actively and having high hsCRP) had 4-fold risk for incident hypertension. Conclusions: Smoking, overweight and increased hsCRP level had risk-predictive value in incident hypertension prediction during long-term follow-up of 21 years. Assessment and measurement of these parameters could be used in help of detecting high risk subjects and primary prevention of hypertension very early on. In addition, the study shows that blood pressure at the middle-age should be followed and treated intensively to prevent hypertension in the older age. KEY MESSAGES: Baseline blood pressure, being overweight and smoking actively are independent predictors of new hypertension during a long-term follow-up of 21 years. Having two or all three risk factors (smoking actively, body mass index over 25 kg/m2, high-sensitive C-reactive protein (hsCRP) level over 3 mg/L) indicates a 4-fold risk for incident hypertension within 21-year follow-up.
Handling Stress and Sample Storage Are Associated with Weaker Complement-Mediated Bactericidal Ability in Birds but Not Bats

Variation in immune defense influences infectious disease dynamics within and among species. Understanding how variation in immunity drives pathogen transmission among species is especially important for animals that are reservoir hosts for zoonotic pathogens. Bats, in particular, have a propensity to host serious viral zoonoses without developing clinical disease themselves. The immunological adaptations that allow bats to host viruses without disease may be related to their adaptations for flight (e.g., in metabolism and mediation of oxidative stress). A number of analyses report greater richness of zoonotic pathogens in bats than in other taxa, such as birds (i.e., mostly volant vertebrates) and rodents (i.e., nonvolant small mammals), but immunological comparisons between bats and these other taxa are rare. To examine interspecific differences in bacterial killing ability (BKA), a functional measure of overall constitutive innate immunity, we use a phylogenetic meta-analysis to compare how BKA responds to the acute stress of capture and to storage time of frozen samples across the orders Aves and Chiroptera. After adjusting for host phylogeny, sample size, and total microbe colony-forming units, we find preliminary evidence that the constitutive innate immune defense of bats may be more resilient to handling stress and storage time than that of birds. This pattern was also similar when we analyzed the proportion of nonnegative and positive effect sizes per species, using phylogenetic comparative methods. We discuss potential physiological and evolutionary mechanisms by which complement proteins may differ between species orders and suggest future avenues for comparative field studies of immunity between sympatric bats, birds, and rodents in particular.
Animal-Assisted Therapy Enhances Resident Social Interaction and Initiation in Long-Term Care Facilities

ABSTRACT Social stimulation is a valuable aspect of therapeutic activities at long-term care facilities, designed to decrease social isolation, maintain or stimulate mental abilities, and increase awareness of the external environment. A study was undertaken at two such facilities to compare the effectiveness of Animal-Assisted Therapy (AAT) with Non-Animal Therapy (NAT) at providing social stimulation, that is, at providing opportunities for patients to engage in social interaction and to initiate social behaviors. While studies have indicated that AAT can improve resident outlook or affect, few have directly studied the social behaviors that might lead to such improvements, or the role the animals themselves might play. We observed 33 patients, both alert and semi- to non-alert, during regular recreational therapy sessions. Most patients were women (29 vs. four men), and geriatric (in their 70's and 80's). Non-Animal Therapies included Arts and Crafts and Snack Bingo, while AAT involved animals from local animal shelters being brought by volunteers to group sessions. Social behaviors naturally divided into Brief Conversations, Long Conversations, and Touch. We determined frequencies and rates of the behaviors, who initiated the behaviors and whether the behaviors were directed at other people or at the animals. Overall, during AAT residents were involved in as much or more conversation with others, including the animals, as residents in Non-Animal Therapy, and were more likely to initiate and participate in longer conversations. The finding that different kinds of therapies seem to encourage different kinds of conversation might be an important consideration when investigating health benefits. The most dramatic differences between therapy types were found in rates of touch: touching the animals during AAT added significantly to resident engagement in, and initiation of, this behavior. Since touch is considered an important part of social stimulation and therapy, the enhancement of this social behavior by the animals is an important, and perhaps undervalued, effect.