Miracle-dz/UniFAR-FTUs huggingface dataset:
Precoder design for asymmetric multi-user two-way AF relaying in cellular systems

Two-way relaying reduces the loss in spectral efficiency caused in a conventional half-duplex relay due to two channel uses per data unit transmitted to the destination. Two-way relaying is possible when two nodes exchange data simultaneously through a relay. In the case of cellular systems, data exchange between base station (BS) and users (UE) is usually not symmetric, e.g., a user (UE1) might have uplink data to transmit during multiple access (MAC) phase, but might not have downlink data to receive during broadcast (BC) phase. This asymmetry in data exchange will reduce the gains of two-way relaying. In the case of infrastructure relays, where there are multiple users communicating through a relay, we propose that the BC phase following the MAC phase of UE1 be used by the relay to transmit downlink data to a second user (UE2). Conventional two-way relaying with symmetric MAC and BC phases must now be modified to asymmetric MAC (BS → RS ← UE1) and BC phases (BS ← RS → UE2), respectively. This will result in UE2 not being able to cancel the back-propagating interference in the usual way. We design precoders using conventional zero-forcing and linear minimum-mean-square-error criteria to mitigate the back-propagating interference at UE2 for an amplify-and-forward (AF) relay. We also propose a novel precoder appropriate for the asymmetric two-way relaying. The sum-rate performance of the proposed precoder is shown to be better than the conventional precoders.
Mixed acinar-endocrine carcinoma of pancreas: A case report and brief review of the literature

Mixed acinar-endocrine carcinoma (MAEC) of the pancreas is a rare entity. We present a 65-year-old Chinese female who was admitted with jaundice and nagging epigastric pain with intermittent diarrhea for 1 month. She eventually underwent abdominal magnetic resonance imaging, which showed an 8×6 cm mass in the head of the pancreas and showed two abnormal lesions in the liver simultaneously. MAEC of the pancreas with synchronous hepatic metastasis was confirmed with immunohistochemistry after Whipple operation and hepatic partial resection of the lesions. Postoperative recovery of this patient was uneventful, and no evidence of recurrence or metastasis was observed after 12 months of follow-up. MAEC of pancreas is thought to be extremely rare and lack of typical clinical symptoms. The prognosis is poor overall, but early detection with complete resection may be beneficial to patients.
Bidding Privacy Preservation for Dynamic Matching Based Spectrum Trading

Spectrum trading benefits secondary users (SUs) with accessing opportunities and primary users (PUs) with monetary gains in cognitive radio networks. In the spectrum trading market, bidding privacy is a serious concern for SUs, since untrustworthy PUs or spectrum traders may leverage bidding information to manipulate the trading or leak SU's bids to other SU competitors for illegal gains. Current centralized privacy preserving spectrum trading designs may incur extra infrastructure deployment, miss many instantaneous spectrum accessing opportunities, and have scalability issues. In this paper, we propose a novel privacy-preserving semi-distributed spectrum trading scheme, which has joint consideration of spectrum reuse, SUs' bidding privacy preservation, and PUs' revenue maximization. We use the conflict graph to characterize SUs' interference relationships, and jointly employ the Paillier Cryptosystem and dynamic matching with evolving preferences to conduct the privacy-preserving spectrum trading in a semi-distributed manner. Through security, complexity and performance analysis, we show that the proposed scheme can effectively preserve the privacy of SUs' bidding values, and notably increase the PUs' revenue and improve spectrum utilization with limited overhead.
Alternativas de política para fortalecer el ahorro de los hogares de menores ingresos: el caso de Uruguay

Resumen En este trabajo se aborda la tematica del fortalecimiento del ahorro en los hogares de bajos ingresos y la disponibilidad de instrumentos adecuados para su estimulo en la economia uruguaya. En primer lugar, se realiza un analisis econometrico que permite resaltar los determinantes mas relevantes en el caso de las familias de bajos ingresos. Los resultados indican que el comportamiento de dichas familias tiene algunas caracteristicas diferenciales, dependiendo del nivel de ingreso, de la fase del ciclo de vida del hogar y del acceso a credito para vivienda. En cambio, no esta afectado por la incertidumbre respecto al nivel de ingreso futuro. El analisis de los instrumentos disponibles en el mercado, muestra que el mas apropiado para la captacion de ahorro de los sectores de mas bajos ingresos son las cajas de ahorro, si bien adolecen de una gran debilidad: remuneran a los depositos con tasas de interes reales poco atractivas y discriminan en contra de los depositos de menor cuantia. Por lo tanto, el desarrollo de alternativas de ahorro en una unidad de cuenta indexada en la inflacion o el salario nominal, podria ser particularmente interesante como mecanismo de estimulo. Ademas, la elevada preferencia por la liquidez que prevalece en estos sectores, implica que la disposicion a mantener depositos en caja de ahorro en el sistema bancario depende de la inexistencia de restricciones sobre el numero de retiros. En este contexto, se vuelve especialmente relevante el papel del ahorro para vivienda como un mecanismo muy apto, tanto por los requerimientos de ahorro previo para el otorgamiento de algunas lineas de credito, como por el ahorro forzoso que implica el repago de los creditos una vez asignados. A raiz de la creacion de un nuevo sistema, el mecanismo de ahorro previo se ha extendido hacia la poblacion de menores ingresos. La informacion disponible y las opiniones de informantes calificados consultados, sugieren que dicha ampliacion aumento significativamente el numero de cuentas. Asimismo, el ultimo plan de vivienda evalua que el esfuerzo de ahorro realizado por las familias de menores ingresos supero ampliamente los minimos establecidos.
Regulation of histone acetylation during meiotic maturation in mouse oocytes

Histone acetylation is an important epigenetic modification implicated in the regulation of chromatin structure and, subsequently, gene expression. Global histone deacetylation was reported in mouse oocytes during meiosis but not mitosis. The regulation of this meiosis‐specific deacetylation has not been elucidated. Here, we demonstrate that p34cdc2 kinase activity and protein synthesis are responsible for the activation of histone deacetylases and the inhibition of histone acetyltransferases (HATs), respectively, resulting in deacetylation of histone H4 at lysine‐12 (H4K12) during mouse oocyte meiosis. Temporal changes in the acetylation state of H4K12 were examined immunocytochemically during meiotic maturation using an antibody specific for acetylated H4K12. H4K12 was deacetylated during the first meiosis, temporarily acetylated around the time of the first polar body (PB1) extrusion, and then deacetylated again during the second meiosis. Because these changes coincided with the known oscillation pattern of p34cdc2 kinase activity, we investigated the involvement of the kinase in H4K12 deacetylation. Roscovitine, an inhibitor of cyclin‐dependent kinase activity, prevented H4K12 deacetylation during both the first and second meiosis, suggesting that p34cdc2 kinase activity is required for deacetylation during meiosis. In addition, cycloheximide, a protein synthesis inhibitor, also prevented deacetylation. After PB1 extrusion, at which time H4K12 had been deacetylated, H4K12 was re‐acetylated in the condensed chromosomes by treatment with cycloheximide but not with roscovitine. These results demonstrate that HATs are present but inactivated by newly synthesized protein(s) that is (are) not involved in p34cdc2 kinase activity. Our results suggest that p34cdc2 kinase activity induces the deacetylation of H4K12 and that the deacetylated state is maintained by newly synthesized protein(s) that inhibits HAT activity during meiosis. Mol. Reprod. Dev. 69: 222–227, 2004. © 2004 Wiley‐Liss, Inc.
h-Caldesmon, a Novel Smooth Muscle-Specific Antibody, Distinguishes Between Cellular Leiomyoma and Endometrial Stromal Sarcoma

The difficulty in distinguishing between smooth muscle and endometrial stromal-derived neoplasms of the uterine corpus is a notorious and clinically relevant problem in pathology of the female genital tract. Immunohistochemistry offers some aid in resolving this difficulty, because the expression of smooth muscle markers is reputed to indicate smooth muscle derivation. This expression, however, is not entirely specific, and difficult cases may still present in which immunohistochemistry is of little help. To explore this problem, the authors evaluated the expression of traditional muscle markers and high-molecular-weight caldesmon (h-cal), an actin and tropomyosin binding protein that has recently been described as a useful muscle marker, in uterine leiomyosarcoma (LMS), cellular leiomyomata (CL), and endometrial stromal sarcoma (ESS). Formalin-fixed and paraffin-embedded tissue sections from nine LMSs, 11 CLs, and 12 ESSs were evaluated with commercially available monoclonal antibodies against smooth muscle actin (SMA), desmin, and h-cal. Established morphologic criteria were used to classify the neoplasms. We found that there was, as expected, a significant difference in the expression of traditional smooth muscle markers (SMA and desmin) between tumors derived from smooth muscle and those derived from endometrial stroma (p = 0.005 for LMS and 0.013 for CL). We further found that h-cal was most useful in distinguishing between CL and ESS (p = 0.01). A significant difference between h-cal expression in LMS versus ESS was not found. Of note, one ESS expressed both SMA and desmin but lacked h-cal expression. Our findings confirm the most useful immunohistochemical data to date; smooth muscle neoplasms are generally distinguishable from endometrial stromal tumors by the expression of conventional muscle markers. We also report here that h-cal is useful more specifically in the differentiation of CL from ESS.
Following the 2008 outburst decay of the black hole candidate H 1743-322 in X-ray and radio

In this paper, we report on radio (Very Large Array and Austrialian Telescope Compact Array) and X-ray (RXTE, Chandra and Swift) observations of the outburst decay of the transient black hole candidate H 1743-322 in early 2008. We find that the X-ray light curve followed an exponential decay, levelling off towards its quiescent level. The exponential decay time-scale is approximate to 4 days and the quiescent flux corresponds to a luminosity of 3 x 10(32)(d/7.5kpc)(2)erg s(-1). This together with the relation between quiescent X-ray luminosity and orbital period reported in the literature suggests that H 1743-322 has an orbital period longer than approximate to 10 h. Both the radio and X-ray light curve show evidence for flares. The radio-X-ray correlation can be well described by a power-law with index approximate to 0.18. This is much lower than the index of approximate to 0.6-0.7 found for the decay of several black hole transients before. The radio spectral index measured during one of the radio flares while the source is in the low-hard state is -0.5 +/- 0.15, which indicates that the radio emission is optically thin. This is unlike what has been found before in black hole sources in the low-hard state. We attribute the radio flares and the low index for the radio-X-ray correlation to the presence of shocks downstream the jet flow, triggered by ejection events earlier in the outburst. We find no evidence for a change in X-ray power-law spectral index during the decay, although the relatively high extinction of N-H approximate to 2.3 x 10(22) cm(-2) limits the detected number of soft photons and thus the accuracy of the spectral fits.
Hybrid Common Femoral Artery Surgical Revascularization Associated to Endovascular Femoropopliteal Recanalization in High-Risk (ASA 3 - 4) Patients: A Seven-Year Period Institutional Experience

Objective: The present study was conceived to analyze the clinical benefit of hybrid interventions with surgical common femoral artery (CFA) reconstruction coupled to superficial femoral/popliteal endovascular recanalization for severe infrainguinal multilevel occlusive disease in high-risk ASA Class 3 - 4 patients. Material and Methods: From August 2008 until May 2015, a series of 143 hybrid infrainguinal interventions in 124 ASA Class 3 - 4 patients were performed in our department for Rutherford category 2 - 6 ischemic presentations. Patient demographics, specific risk factors, technical characteristics and patency results were retrospectively examined during a mean 36.8 months of follow-up. In a majority of 94 limbs (65%), the endovascular stage of interventions focused on long (>15 cm) femoropopliteal occlusions in parallel to regular CFA surgical revascularization. Two or three runoff tibial trunks were evinced in 84% cases, while one or none permeable vessel was found in 23 (16%) limbs. Results: Inasmuch surgical approach was successful in all cases, the endovascular stage was technically profitable in 134 (93%) cases. The ABI posto-peratively improved (>1.5) in 73% of cases, while clinical presentation gained at least one Rutherford category in 89% limbs. The mean hospital stay was 6.1 days (3 - 12 days) whereas the 30-day mortality rate in this homogeneous “high-risk” group of patients was 3.2%. Global risk factors alike age (>70 years/p = 0.0005), smoking ((p = 0.0170) and female gender (p = 0.0111), together with CTOs length (>15 cm/(p = 0.0470), severe calcifications (p = 0.0001), poor tibial runoff (p = 0.0001), TASC “C” and “D” lesions (p = 0.360 and (p = 0.0394), the stent number ((n = 3) and length (>6 cm) ((p = 0.0039 and (p = 0.0003) and the initial ABI scoring ((p = 0.0051) showed statistical negative influence on primary patency. Conclusion: Hybrid infrainguinal revascularization may afford useful results in selected ASA “high risk” patients, owning low invasiveness, reproducibility and acceptable patency in return to punctual postoperative surveillance.
An Empirical Test of the Mobile Services Acceptance Model

This paper presents a mobile services acceptance model, which includes aspects of trust, contextual fit, and personal initiatives and characteristics in addition to perceived usefulness and perceived ease of use from the technology acceptance model (TAM). The proposed research model was empirically tested using data collected from a survey of 25 users of a mobile service called Mobile Student Information Systems (MSIS). The results reveal that the fitness of the acceptance model is quite good. Our findings indicate that personal initiatives and characteristics, trust, and perceived ease of use are key determinants for the users to adopt the mobile service. Context via its influence on perceived usefulness and perceived ease of use has an indirect affect on intention to use. Furthermore, a striking finding is the negative influence of perceived usefulness on intention to use.
Systematic review of peri-operative nutritional support for patients undergoing hepatobiliary surgery.

BACKGROUND Malnutrition is prevalent among peri-operative patients undergoing hepatobiliary surgery and is an important prognostic factor. Both hepatobiliary disease and surgical trauma significantly affects body's metabolism and environment. Therefore, it is very important for patients with liver diseases undergoing hepatobiliary surgery to receive essential nutritional support during peri-operative period. METHODS We summarized our clinical experience and reviewed of related literature to find the way for implementing the appropriate nutritional strategy. RESULTS We found after comprehensively evaluating nutrition status, function of liver and gastrointestinal tract, nutritional strategy would be selected correctly. In severe malnutrition, initiation of enteral nutrition (EN) and/or parenteral nutrition (PN) with essential or special formulae is often recommended. Especially nasojejunal feeding is indicated that early application can improve nutritional status and liver function, reduce complications and prolong survival. CONCLUSIONS The reasonable peri-operative nutritional support therapy can improve the effect of surgical treatment and promote the patients' recovery.
Immunohistochemical staining of human islet cells with region‐specific antibodies against secretogranins II and III

Chromogranins and secretogranins belong to the granin family of proteins, which are expressed in neuroendocrine and nervous tissue. In earlier publications we have described the development of region‐specific antibodies against CgA and CgB. In this study we describe antibodies to SgII and SgIII and their usefulness for immunohistochemical staining. Peptides homologous to defined parts of secretogranins II and III were selected and synthesized. Antibodies were raised and immunostainings were performed on normal human pancreas. The SgII 154–165 (N‐terminal secretoneurin), SgII 172–186 (C‐terminal secretoneurin) and SgIII antibodies immunostained all insulin‐immunoreactive cells, most of the glucagon cells and some of the pancreatic polypeptide cells. The SgII 225–242 antibody immunostained only the insulin‐containing cells. None of the antibodies immunostained the somatostatin cells. This study is the first observation of the expression of SgIII in human tissues, where we show expression of SgIII in three of the four major islet cell types in human pancreas.
Effect of Reduced Vancomycin Susceptibility on Clinical and Economic Outcomes in Staphylococcus aureus Bacteremia

ABSTRACT Reduced vancomycin susceptibility (RVS) may lead to poor clinical outcomes in Staphylococcus aureus bacteremia. The objective of this study was to evaluate the clinical and economic impact of RVS in patients with bacteremia due to S. aureus. A cohort study of patients who were hospitalized from December 2007 to May 2009 with S. aureus bacteremia was conducted within a university health system. Multivariable logistic regression and zero-truncated negative binomial regression models were developed to evaluate the association of RVS with 30-day in-hospital mortality, length of stay, and hospital charges. One hundred thirty-four (34.2%) of a total of 392 patients had bacteremia due to S. aureus with RVS as defined by a vancomycin Etest MIC of >1.0 μg/ml. Adjusted risk factors for 30-day in-hospital mortality included the all patient refined-diagnosis related group (APRDRG) risk-of-mortality score (odds ratio [OR], 7.11; 95% confidence interval [CI], 3.04 to 16.6), neutropenia (OR, 13.4; 95% CI, 2.46 to 73.1), white blood cell count (OR, 1.05; 95% CI, 1.01 to 1.09), immunosuppression (OR, 6.31; 95% CI, 1.74 to 22.9), and intensive care unit location (OR, 3.51; 95% CI, 1.65 to 7.49). In multivariable analyses, RVS was significantly associated with increased mortality in patients with S. aureus bacteremia as a result of methicillin-susceptible (OR, 3.90; 95% CI, 1.07 to 14.2) but not methicillin-resistant (OR, 0.53; 95% CI, 0.19 to 1.46) isolates. RVS was associated with greater 30-day in-hospital mortality in patients with bacteremia due to methicillin-susceptible S. aureus but not methicillin-resistant S. aureus. Further research is needed to identify optimal treatment strategies to reduce mortality associated with RVS in S. aureus bacteremia.
Experimental Performance Assessment of SPM for SPECT Neuroactivation Studies Using a Subresolution Sandwich Phantom Design

The validity domain of voxel-based statistical analysis of SPECT neuroactivation studies with statistical parametric mapping (SPM) has been investigated by a limited number of theoretical and simulation studies. In this work, an experimental setup is described with an assessment of its activation detection performance together with the influence of acquisition and processing parameters. A subresolution sandwich phantom was constructed using a printed high-resolution digital Hoffman phantom with a (99m)TcO(4)-ink mixture. Activations of 8, 16, and 24 mm diameter, with an intensity ranging from 5 to 60%, were constructed in the right frontal cortex, anterior and posterior cingulate, and left striatum. Triple-headed SPECT acquisitions were carried out using both fan-beam and parallel beam geometry. The impact of activation characteristics (size, intensity and location), study size, physical degradation factors, and reconstruction technique were studied using SPM99 in a group comparison design with correction for multiple comparisons. For a 15 x 15 design, all 24-mm activations of 5% intensity were detected for the fan-beam data. Decreased focus or study size, lower SPECT resolution, absence of scatter, and attenuation correction resulted in an increase in minimally detectable activation. For a single study referred to 15 control studies, only 24-mm activation foci with a minimal intensity of 10% were detected in the optimal configuration. This approach allows experimental parameter optimization of SPM-based group or single-subject SPECT activation studies compared to normal data, as used in clinical applications. In principle, these findings can be extended to SPECT receptor studies or PET data.
Children’s strategic theory of mind

Significance Human interaction requires reasoning not only about other people’s observed behavior and mental states but also about their incentives and goals. The development of children’s strategic thinking is not well understood, leaving open critical questions about early human capacity for strategic interaction. We investigated strategic reasoning in 3- to 9-y-old children and adults in two strategic games that represent prevalent aspects of social interaction: incentives to mislead and competition. We find that despite strategic differences in the two games, by the age of 7 y, children’s behavior is similar to that of adults. Our findings also show an early sophisticated ability to think strategically about others in both static and repeated interactions. Human strategic interaction requires reasoning about other people’s behavior and mental states, combined with an understanding of their incentives. However, the ontogenic development of strategic reasoning is not well understood: At what age do we show a capacity for sophisticated play in social interactions? Several lines of inquiry suggest an important role for recursive thinking (RT) and theory of mind (ToM), but these capacities leave out the strategic element. We posit a strategic theory of mind (SToM) integrating ToM and RT with reasoning about incentives of all players. We investigated SToM in 3- to 9-y-old children and adults in two games that represent prevalent aspects of social interaction. Children anticipate deceptive and competitive moves from the other player and play both games in a strategically sophisticated manner by 7 y of age. One game has a pure strategy Nash equilibrium: In this game, children achieve equilibrium play by the age of 7 y on the first move. In the other game, with a single mixed-strategy equilibrium, children’s behavior moved toward the equilibrium with experience. These two results also correspond to two ways in which children’s behavior resembles adult behavior in the same games. In both games, children’s behavior becomes more strategically sophisticated with age on the first move. Beyond the age of 7 y, children begin to think about strategic interaction not myopically, but in a farsighted way, possibly with a view to cooperating and capitalizing on mutual gains in long-run relationships.