Miracle-dz/UniFAR-FTUs huggingface dataset:
Social support as a predictor of participation in cardiac rehabilitation after coronary artery bypass graft surgery.

PURPOSE Cardiac rehabilitation promotes recovery and enhances quality of life after a coronary artery bypass graft (CABG), but participation in such rehabilitation is low. The role of social support in promoting participation has been suggested by prior studies, but is not clearly defined. The purpose of this study was to investigate the role of social support as an independent predictor of participation in cardiac rehabilitation. METHODS This study examined 944 patients who underwent first isolated CABG between May 1999 and February 2001, then were followed for 6 months after surgery. Social support before CABG and 6 weeks after CABG was assessed using the Enhancing Recovery in Coronary Heart Disease (ENRICHD) Social Support Inventory (ESSI) and evaluated for its association with participation in cardiac rehabilitation. RESULTS Of 944 patients, 524 (56%) reported participation in rehabilitation. The participants were younger, better educated, more often employed, and less financially strained. The participants also had a lower prevalence of cardiovascular disease risk factors and better physical function. According to unadjusted analysis, the patients with low social support (ESSI </= 22) before surgery were less likely to participate in rehabilitation than the other patients (52% vs 59%; risk ratio [RR], 0.89; 95% confidence interval [CI], 0.78-0.99). However, adjustment for demographic factors, medical history, cardiovascular disease risk factors, physical and psychological function, and hospital complications attenuated this association (adjusted RR, 0.92; 95% CI, 0.78-1.07). A low ESSI score measured 6 weeks after CABG similarly did not significantly affect participation in rehabilitation (adjusted RR, 0.96; 95% CI, 0.81-1.11). CONCLUSIONS Contrary to what is believed generally, social support may not be a strong determinant of participation in rehabilitation after CABG. Correlates of social support such as gender, socioeconomic status, and comorbidity burden may have a more important role in cardiac rehabilitation participation than social support itself. When marital status was examined as a main predictive variable, the analyses yielded similar results (unadjusted RR, 0.72; 95% CI, 0.58-0.86; RR adjusted for the same covariates, 0.80; 95% CI, 0.60-1.02).
Hafnium isotope ratios of nine GSJ reference samples

176Hf/177Hf ratios of nine geochemical reference rocks from the Geological Survey of Japan, together with BIR-1 and BCR-2, were determined using multi-collector inductively coupled plasma mass spectrometry. Our data for BIR-1, BCR-2 and JB-1 are in agreement with those previously reported, demonstrating the appropriateness of the chemical procedure and isotopic measurement employed in this study. The reference rocks have a wide range of 176Hf/177Hf covering the field defined by various volcanic rocks, such as mid-ocean ridge basalts, ocean island basalts, and subduction related volcanic rocks. They are therefore suitable as rock standards for Hf isotope measurement of geological samples.
INFLUENCE OF DIETARY ANIMAL FAT AND PLANT OIL ON GROWTH PERFORMANCEOFJAPANESE QUAIL

An experiment was conducted to investigate the effects of different dietary oil and fat sources including soybean oil (SO), corn oil (CO) and beef tallow (BT) used as energy sources on growth performance, fatty acids composition of breast muscle and some blood parameters of Japanese quail. A total number of 360 unsexed one day old Japanese quail chicks were randomly distributed into threedietary treatment groups.The first treatment received diet withcorn oil (CO), the second treatment fedanimal fat beef tallow (BT) diet and the third treatment contain soybean oil(SO) as a dietary energy sources which added to diets to substitute 4% of the diet energy.Each dietary treatment was represented in triplicates. The experimental diets were formulated to contain 24% crude protein each with energy levels (2900 Kcal ME/Kg). Results obtained are summarized in the following: 1-The highest (P<0.05) average final weights at 6 week of age was recorded by the (SO) group, while the lowest (P<0.05) valuewas recorded by(BT) group, although the difference between (CO) and (SO) groups was insignificant. 2-The best feed conversion ratio (FCR) (P<0.05) was recorded by the both (SO) and (BT) groups, respectively.Whereas the differences between (CO) group and other groups (BT and SO) in this traitweresignificant. 3-The best energy conversion ratios (P<0.05) were recorded by the (SO) and(BT)groups, respectively compared to corn oil (CO) group. 4-The performed nutritional treatments released significant effects on plasma total lipids, plasma total triglycerides, plasma total cholesterol, plasma HDL and plasma LDL. 5-The highest value of saturated fatty acids in breast meat was recorded by the (BT) group,while the highest value for unsaturated fatty acids in breast meat was recorded by the (CO)group.
Non-ionic surfactants as novel intranasal absorption enhancers: in vitro and in vivo characterization

Abstract Objective: To explore the potential of non-ionic surfactants as novel intranasal absorption enhancers. Methods: Taking sumatriptan succinate (SMS) as a model drug, influence of different non-ionic surfactants, including laurate sucrose ester (SE), cremophor EL and poloxamer 188, on the intranasal absorption of SMS was investigated using an in situ nasal perfusion technique in rats. Ciliotoxicity of the non-ionic surfactants was evaluated using an in situ toad palate model. In vivo behavior of the selected formulations was studied in rats. Results: All the non-ionic surfactants investigated increased the intranasal absorption of SMS remarkably but with varied extent and trend. Moreover, it was revealed that at the same concentration, laurate SE had better permeation-enhancing effect than that of cremophor EL and poloxamer 188. The ciliotoxicity results showed that all the non-ionic surfactants were regarded as safe at selected concentrations. Based on the in situ absorption data and ciliotoxicity results, the following three samples, 0.5% laurate SE, 0.1% cremophor EL and 0.5% poloxamer 188 were selected for in vivo absorption studies in rats. Among them, 0.5% laurate SE group presented the highest enhancing effect, followed by 0.1% cremophor EL and 0.5% poloxamer 188 group, with absolute bioavailability 29.99%, 22.64% and 20.90%, respectively. Conclusions: Laurate SE is a promising intranasal absorption enhancer.
The impact of spatial scale on spatial variability in hydrologic response: experiments and ideas.

Le projet MARVEX mene au Nord de la Nouvelle-Zelande s'interesse a la variabilite spatiale de la reponse hydrologique grâce a la combinaison de mesures detaillees, de modelisation numerique et de developpements theoriques. Les 50 km 2 du bassin de la riviere Mahurangi ont ete abondamment instrumentes pendant plusieurs annees pour observer la variabilite spatio-temporelle de la pluie, de l'humidite du sol et de l'ecoulement. Les objectifs du projet sont: (a) d'observer la variabilite spatiale de la reponse hydrologique; (b) d'identifier les causes de la variabilite observee; (c) de comprendre pourquoi certaines de ces causes sont plus importantes que d'autres. MARVEX s'est davantage interesse a la variabilite spatiale qu'a l'echelle spatiale. Le present papier discute du lien existant entre variabilite spatiale et echelle spatiale, presente une revue des developpements conceptuels qui les lient, et illustre ces differents points a partir de MARVEX. Je suggere que l'hydrologie est plus complexe que ce que ne laisse supposer les approches scalantes, et que si des lois d'invariance d'echelle simples et elegantes peuvent exister, elles ont certainement des domaines d'application limites. Ce dernier point conduit naturellement au besoin d'un systeme de classification ou a un ensemble de variables de similitude concertes en hydrologie.
Understanding Open Source Communities as Complex Adaptive Systems: A Case of the R Project Community

Open source communities evolve. This evolution is, at times, driven by corporate engagement with those communities. In these corporate-communal contexts, open source foundations often serve as facilitators in the evolution process and make these arrangements more stable over time. This paper expands the application of complex adaptive systems (CAS) theory to understand the role of open source foundations as facilitators in the evolution of corporate-communal arrangements. We present the case of the R Project community and how we can leverage complex adaptive systems as a way to understand the evolution of the community as driven by corporate engagement and facilitated by open source foundations. We develop the theory of CAS by enhancing the understanding of attractors in the evolution of CAS.
Effect of temperature on the growth of Myxococcus xanthus

The cardinal growth characteristics of Myxococcus xanthus were examined from 14 to 40 degree C, and the examinations indicated that the organism is mesophilic in character. The maximum growth rate (0,3 doublings per h) was between 34 and 36 degree C and the temperature characteristic (micron) is 17,000 cal/mol (71,162 J/mol).
Anaplastic Lymphoma Kinase (ALK) Expression in the Inflammatory Myofibroblastic Tumor: A Comparative Immunohistochemical Study

Inflammatory myofibroblastic tumor (IMT) is an uncommon mesenchymal neoplasm with a variable histologic appearance that may mimic other spindle cell processes, particularly nodular fasciitis, desmoid tumor, and in intra-abdominal locations, gastrointestinal stromal tumor. Recently, gene fusions involving ALK at chromosome 2p23 have been described in IMTs. The resultant ALK protein overexpression in the myofibroblastic component of these tumors is detectable by immunohistochemistry. We examined 73 IMTs, 20 cases of nodular fasciitis, 15 desmoid fibromatoses, and 15 gastrointestinal stromal tumors by immunohistochemistry using ALK-11, a rabbit polyclonal antibody that recognizes the C-terminus of the protein. ALK positivity was detected in 44 of 73 (60%) IMTs. All cases of nodular fasciitis, desmoid fibromatosis, and gastrointestinal stromal tumors were ALK negative (p < 0.001). These findings demonstrate that ALK positivity is common in IMTs, and immunohistochemistry using anti-ALK antibodies can be helpful in the differential diagnosis of these neoplasms. In addition, anti-ALK staining seems to correlate with those IMTs that have the typical tri-patterned histologic appearance and clinical presentation, providing additional support to the premise that IMT is a distinctive clinicopathologic entity within the broad category of inflammatory pseudotumors.
Variation in the treatment of children by primary care physician specialty.

OBJECTIVE To investigate specialty differences in the treatment of a diverse array of routine childhood problems. STUDY DESIGN Analysis of the first round of the Community Tracking Study Physician Survey, a survey designed to assess the effect of corporatization of medicine on physician practice patterns. PARTICIPANTS A cohort of 1735 pediatricians and 1267 family practitioners interviewed between 1996 and 1997 for round 1 of the Community Tracking Study. Physicians practicing more than 20 hours per week in the United States, whose primary specialty is either general pediatrics or family practice were included. MAIN OUTCOME MEASURE Physicians' responses to 6 vignettes describing model patients with clinical presentations contrived to have multiple appropriate treatment plans. RESULTS Relative to general pediatricians, family practitioners are more likely to: (1) recommend desmopressin acetate for primary enuresis (58.9% vs 37.4%); (2) request an office visit for a child with nasal stuffiness, fever, and no other symptoms (69.8% vs 63.3%); (3) recommend a chest x-ray for a child with productive cough, tachypnea, and rales at the right base (51.3% vs 47.7%); (4) refer a 4-year-old child with eczema and seasonal asthma to an allergist (64.3% vs 59.2%); and (5) refer a child with recurring suppurative otitis media to an otolaryngologist (49.7% vs 33.9%). However, family practitioners are significantly less likely than pediatricians to order a sepsis workup on a 6-week-old infant with a temperature of 38.3 degrees C (66.4% vs 81.1%). Physician attributes, practice characteristics, referral patterns, and geographical traits explain little of these differences in practice style. CONCLUSIONS On average, there are significant differences between the approaches of pediatricians and family practitioners to the treatment of children, which may relate to the relative experience that each profession has in treating children.
Phosphorylation-Dependent Interaction of Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein (YWHA) with PADI6 Following Oocyte Maturation in Mice1

Abstract Proteins in the tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein family (YWHA; also known as 14-3-3) are involved in the regulation of many intracellular processes. We have examined the interaction of YWHA with peptidylarginine deiminase type VI (PADI6), an abundant protein in mammalian oocytes, eggs, and early embryos. Peptidylarginine deiminases catalyze the posttranslational modification of peptidylarginine to citrulline. PADI6 is associated with oocyte cytoplasmic sheets, and PADI6-deficient mice are infertile because of disruption of development beyond the two-cell stage. We found that PADI6 undergoes a dramatic developmental change in phosphorylation during oocyte maturation. This change in phosphorylation is linked to an interaction of PADI6 with YWHA in the mature egg. Recombinant glutathione S-transferase YWHA pull-down experiments and transgenic tandem affinity purification with liquid chromatography-mass spectrometry demonstrate a binding interaction between YWHA and PADI6 in mature eggs. YWHA proteins modulate or complement intracellular events involving phosphorylation-dependent switching or protein modification. These results indicate that phosphorylation and/or YWHA binding may serve as a means of intracellular PADI6 regulation.
Phosphorylated Tau Epitope of Alzheimer's Disease Is Coupled to Axon Development in the Avian Central Nervous System

The monoclonal antibody PHF-1 recognizes phosphorylated tau isoforms present in paired helical filaments of Alzheimer's disease. We have found that PHF-1 immunoreactivity is present in chick brain, which expresses three major PHF-1-reactive proteins at the same molecular weights seen in humans. The developmental pattern of expression suggests a functional role in differentiation, rather than in programmed nerve cell death. Expression of PHF-1 immunoreactivity in developing retina was highly cell selective, showing robust staining of ganglion cells, the only long-axon neuron of the seven major retina cell types. The majority of ganglion cells were PHF-1 positive. The developmental window of expression extended at least from E6 through P0, well outside the period of embryonic ganglion cell death. Mature cells did not show PHF-1 immunoreactivity. In the embryo, staining was particularly robust in ganglion cell axons (optic fiber layer), and association of PHF-1 reactivity with axonal tracts also was seen in developing forebrain. PHF-1 polarization occurred at ages when staining with polyclonal anti-tau did not show axonal selectivity. Similarly, in cell cultures, PHF-1 immunoreactivity became localized to single neurites, but polyclonal anti-tau did not. These results indicate that, rather than being associated with cell degeneration, PHF-1 immunoreactivity in the developing nervous system is associated with early stages of axon formation, both in vivo and in vitro. Therefore, expression of PHF-1 immunoreactive proteins in Alzheimer's disease suggests that paired helical filament formation might be triggered by mechanisms related to axon regeneration.
Win or Lose the Battle for Creativity: The Power and Perils of Intergroup Competition

Integrating and refining social interdependence theory and structural adaptation theory, we examined the effects of intergroup competition on the creativity of 70 four-person groups engaged in two idea generation tasks. We manipulated both group membership change (change, no change) and intergroup competition level (low, intermediate, high). Competition had the expected U-shaped relation with creativity in open (membership change) groups but failed to produce the hypothesized inverted U-shaped pattern in closed (no membership change) groups. In the latter, effects were positive for low to intermediate competition and flat for intermediate to high levels. Within-group collaboration mediated these effects.
[Analysis of volatile components from the flowers of Chrysanthemum morifolium by GC-MS with solid-phase microextraction].

OBJECTIVE To study a method for extraction and analysis of volatile components from Chrysanthemum morifolium 'gonghuangjv' cv. nov (CM GHJ) and C. morifolium 'gongbaijv' cv. nov (CM GBJ) by solid-phase microextraction (SPME) and gas chromatography-mass spectrometry (GC-MS). METHOD The volatile components were extracted in different temperature, different balance period and different extraction fiber using head space solid-phase microextraction (HS-SPME), and were identified by CGC-MS. The variety in integral area of each component was observed in different conditions and its relative content was determined by normalization of area. RESULT The better condition of SPME for C. morifolium was that the sample was extracted using 100 microm polydimethylsiloxane (PDMS) extraction fiber after it had been balanced for 6 hours at 75 degrees C. 53 components from CM GHJ and CM GBJ were identified, and there were 35 same components in CM GHJ and CM GBJ. CONCLUSION HS-SPME-GC-MS is convenient, rapid and reliable for analysis of volatile components in C. morifolium.
Fever in pulmonary embolism

This study was planned to investigate the characteristics of clinical and laboratory findings of patients with fever diagnosed as pulmonary embolism (PE) in comparison with PE patients without fever and patients with community-acquired pneumonia (CAP). Thirty-nine PE patients with fever without other identifiable causes (18 received antibiotics and 21 did not receive antibiotics) (study groups) were included in the study. 22 patients with PE without fever and 21 patients diagnosed with CAP were retrospectively selected as control groups. Daily peak body temperature, risk factors for PE, symptoms, and physical and laboratory findings at admission were recorded. Patients with CAP demonstrated higher body temperature than PE patients with fever (38.5 ± 0.6 versus 37.8 ± 0.6°C, P = 0.0001). Fever patterns were similar between the three groups of patients who had fever. The leukocyte count and the erythrocyte sedimentation rate (ESR) were slightly higher in the group of PE with fever versus PE without fever (11 465.6 ± 4229.4/mm3, 51.1 ± 34.7/mm/h versus 10 777.3 ± 4927.6/mm3, 35.2 ± 30.1/mm/h, respectively) (P > 0.05). The group of CAP showed significantly highest values of leukocyte count and ESR (15 490.5 ± 5606.3/mm3, 69.1 ± 35.9/mm per h, respectively) (P < 0.05). This study suggested that fever might accompany with PE. The presence of slight leukocytosis and increased ESR may not securely differentiate PE patients with fever from patients with CAP.
Prevalence and annual incidence of psychosis in patients with epilepsy

All patients visiting our adult epilepsy clinic at the present time (June, 1994) were the subjects of investigation. The hospital records were reviewed retrospectively from their first visit to our clinic. Epilepsy types and seizure types were determined according to the international classification. Paranoid psychosis consisted of delusion, mostly of reference and persecution with or without hallucination and may be episodic (mostly interictal and unrelated to ictal events but some are postictal) or may be chronic schizophrenia-like form.
Development of a simulation environment for economic impacts of distributed generation and energy storage on distribution feeders

System planning for incorporation of electric energy storage systems into a distribution network requires consideration of a range of technical and economic variables. A modeling system with a graphical user interface has been developed to incorporate an accurate system model of a distribution feeder including distributed generation and energy storage located along the feeder, as well as economic parameters. Output of the model represents a time history of the simulated feeder with the given parameters and time profiles of loads, generation, and storage systems. In addition to active power flows, the model also accounts for reactive power flows, with the capability of for reactive compensation from renewable generation and energy storage inverters. The cost of energy via Locational Marginal Pricing (LMP) and Renewable Energy Credits (RECs) is incorporated. This paper describes the modeling system and provides example results for an actual feeder in the Eastern Massachusetts LMP area.
The Bayesian equation and psychosis.

Sir, Chambon et al . (2011) use the Bayesian equation to design an exacting experiment to differentiate the responses of psychotic subjects and controls in a variety of ‘mentalizing’ tasks. Psychotic subjects correctly inferred basic non-social intentions, but in the non-social superordinate condition they relied on prior expectations over sensory evidence, a finding that correlated with positive symptoms. Social paradigms showed less dependence on prior conditions and more reliance on sensory evidence, which correlated with negative symptoms. What conclusions might be drawn if one were to apply their results and the Bayesian equation directly to psychosis in vivo as typically observed in clinical practice? Clinical experience suggests that the errors in judgement in psychosis involve particular combinations and exaggerations of biases found in non-psychotic individuals (Bentall et al ., 2001), coupled with departures from the Bayesian equation, which may be unique to psychosis. In the simplest form of the Bayesian equation, the probability that a belief ‘B’ is true\the probability it is not true, after receiving information ‘D’, is a function of four independent variables arrayed as two ratios, the likelihood ratio and the prior odds (PO) ratio (Fischoff and Beyth-Marom, 1983; Hemsley and Garety, 1986). The likelihood ratio is the information value of data D with respect to belief B being true (D true) divided by the information value of D for B being false (D false). The PO ratio is the likelihood of B being true in light of all experience prior to D (PO true) divided by the likelihood …