Miracle-dz/UniFAR-FTUs huggingface dataset:
IMPLEMENTATION OF BIOFEEDBACK IN A CLOSED LOOP OF HEART RATE VARIABILITY AND PACED BREATHING IN PATIENTS WITH ARTERIAL HYPERTENSION

STPI Central clinical hospital «Ukrainian railway»,Kharkiv, Ukraine The effectiveness of biofeedback in a closed loop of heart rate variability (HRV) and paced breathing in patients with arterial hypertension was studied. 61 subjects with arterial hypertension (31 females and 30 males, mean age 56.8 ± 6.2 years) were examined. In accordance with the objective of the study all subjects were divided into 2 groups: 1 - biofeedback group (34 subjects) and 2 - the comparison group (27 subjects). 5 biofeedback sessions were performed in biofeedback group. In the comparison group only two biofeedback sessions were performed - at admission and before discharge from the hospital. Efficacy of biofeedback was evaluated by comparing the values of systolic and diastolic blood pressure (SBP and DBP, respectively), heart rate (HR), HRV indices, indicators of optimality (O), sensitivity (S) and efficiency (E) and BQI index at admission and discharge in both groups of patients. The use of biofeedback in arterial hypertension subjects allowed to achieve better control of heart rate, systolic and diastolic blood pressure and improves HRV indices. The positive dynamics of optimality and the integral BQI values indicated a training effect of regulation systems. KEY WORDS: arterial hypertension, biofeedback, heart rate variability, paced breathing ЗАСТОСУВАННЯ БІОЛОГІЧНОГО ЗВОРОТНОГО ЗВ'ЯЗКУ В ЗАМКНУТОМУ КОНТУРІ ВАРІАБЕЛЬНОСТІ СЕРЦЕВОГО РИТМУ І МЕТРОНОМІЗОВАНОГО ДИХАННЯ У ПАЦІЄНТІВ З АРТЕРІАЛЬНОЮ ГІПЕРТЕНЗІЄЮ О. Л. Кулик
Prediction of Ovarian Response by Antimullerian Hormone in Women with Polycystic Ovarian Syndrome: A Randomized Prospective Study

AMH is synthesized specifically by granulose cells of developing ovarian preantral and small antral follicles. Circulating AMH levels in women with PCOS are 2to 3-fold more compared to ovulatory women with normal ovaries [6,7], which denotes to the 2to 3-fold rise in the count of small follicles detected in PCOS. The excessive AMH has been hypothesized to decrease follicle sensitivity to FSH induction and oestradiol production, so hindering follicle selection, resulting in follicular maturation arrest at the small antral phase with the failure to reach maturity.
A study of coverage optimized planning incorporating models of geometric uncertainties for prostate cancer

A STUDY OF COVERAGE OPTIMIZED PLANNING INCORPORATING MODELS OF GEOMETRIC UNCERTAINTIES FOR PROSTATE CANCER By Huijun Xu, B.S. A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University. Virginia Commonwealth University, 2013. Major Director: Jeffrey V. Siebers, Ph.D. Professor and Director, Medical Physics Graduate Program Department of Radiation Oncology A fundamental challenge in the treatment planning process of multi-fractional externalbeam radiation therapy (EBRT) is the tradeoff between tumor control and normal tissue sparing in the presence of geometric uncertainties (GUs). To accommodate GUs, the conventional way is to use an empirical planning treatment volume (PTV) margin on the treatment target. However, it is difficult to determine a near-optimal PTV margin to ensure specified target coverage with as much normal tissue protection as achievable. Coverage optimized planning (COP) avoids this problem by optimizing dose in possible virtual treatment courses with GU models directly incorporated. A near-optimal dosimetric margin generated by COP was reported to savvily accommodate setup errors of target and normal tissues for prostate cancer treatment.
Bebek Ve Çocuklarda Geçici Hiperfosfatazemi: 43 Olguluk Retrospektif Bir Çalişma

Amac: Klinigimizde 3 yillik bir sure boyunca yuksek plazma ALP duzeylerinin prevalansini ve klinik ozelliklerini tanimlamak. Gerec ve Yontem: artmis ALP duzeyleri olan 5 yasin altindaki 533 cocugunu geriye donuk olarak taradik ve frekans, mevsimsel dalgalanma, yas dagilimi ve cinsiyet farkliliklarini arastirdik. Bulgular: Yirmi dort hasta (% 55.8) kizdi ve yas ortalamasi 7.48 ± 12.77 (1-60) ay idi. Ortalama alkalin fosfataz (ALP) duzeyi 1402.23 ± 440.4 U / L (1038-3135 U / L) ve ust araliktan 3.33 ± 1.04 (2.47-7.46) kat daha yuksekti. ALP seviyeleri, ortalama 2.5 ± 1.1 (1-5) aylik bir sure icinde normale dondu. Sonuc: Bu iyi huylu antitenin erken taninmasi, gereksiz testlerden kacinmaya yardimci ollabilir
Polymorphism of Cyp1a1 (T6235C) is not a significant risk factor of osteoporosis in postmenopausal Indonesian woman

Osteoporosis is an increasingly common disease resulting in reduced bone mineral density (BMD) and elevated likelihood of bone fracture, and particularly affected are postmenopausal women with additional risk factors including genetic predisposition. The CYP1A1, is one of the candidate genes that have been suggested to be associated with the pathogenesis of osteoporosis. This work aimed to evaluate the distribution of a selected polymorphism of this gene (T6235C) with respect to the BMD status in postmenopausal Indonesian women. The results show that osteoporosis is associated with age and menopause, as expected, but not with the tested polymorphism of CYP1A1 in the Indonesian sample population. It is suggested that other P450 cytochrome enzymes and their polymorphisms could provide more significant indicators of the future health of postmenopausal women.
Archives of Pulmonology and Respiratory Care Clinical and Functional Outcomes of Sensitizer-Induced Asthma in Bakers and Cotton Workers after Removal from Exposure

Introduction. Sensitizer-induced occupational asthma (OA) has significant health and socioeconomic outcomes in affected subjects. Objective. To evaluate clinical and functional outcomes of sensitizer-induced OA in bakers and cotton workers three to five years after cessation of exposure to the offending workplace agent. Methods. We studied 16 patients with sensitizer-induced OA (10 bakers and 6 textile workers), eight males and eight females, aged 32 to 48 years. All study subjects completed a questionnaire and underwent spirometric measurements and metacholine challenge, in the same manner as at the time of diagnosis. The findings obtained were compared with findings registered at the time of diagnosis. Results. We found significantly lower prevalence of patients with respiratory symptoms in the previous 12 months after the mentioned period of removal from exposure than their prevalence at the time of diagnosis (100% vs. 68.7%; P = 0.014). In regard to nasal symptoms, their prevalence at the time of the study was lower than at the time of diagnosis but statistical significance was not reached (62.5% vs. 37.5%; P = 0.107). The values of spirometric parameters at the time of the study were similar to their values at the time of diagnosis. The level of the non-specific bronchial hyper responsiveness (NSBHR) at the time of the study was improved in all study subjects. The mean value of the provocative concentration 20 (PC 20 ) at the time of the study was significantly higher than its mean value registered at the time of diagnosis (2.9 vs. 2.1; P = 0.032). However, none subject normalized his/her NSBHR. Conclusions. Our findings indicate resolution of the respiratory and nasal symptoms in a part of the study subjects. In addition, all study subjects are left with their NSBHR, although all of them improve.
Difference in localization of eosinophils and mast cells in the bovine ovary

The bovine ovary contains a considerable number of leucocytes which can be located with an antibody against the CD18 molecule. In the present study, subtyping and cell counting were carried out on histological sections stained with Sirius red for eosinophils and with toluidine blue for mast cells. The CD18 + cells were identified immunohistologically. Eosinophils and mast cells contributed considerably to the CD18 + pool. The number of eosinophils in the corpus luteum increased rapidly in early development to approximately 90% of the CD18 + cells, and decreased to 30% during secretion and to 10% during regression. Mast cells were not detectable in the follicles, the corpus luteum and the periphery of the cortex, but were observed in the interstitial cortical stroma and the medulla. The number of mast cells in these regions, which corresponded to 60-76% of the CD18 + cells, did not change significantly throughout the oestrous cycle. It is concluded that eosinophils are selectively recruited at the periovulatory period and that mast cells are unevenly distributed.
Circadian changes of the rat pancreas acinar cell. A quantitative morphological investigation.

The dynamics of the physiologic secretory cycle of the rat pancreatic acinar cells along a 24-h span with an alternating 12 : 12 light to dark cycle have been quantitated by morphometric methods. Significant circadian changes could be detected in cell volume and the volumes and surface areas of secretory granules and several organelles involved in the secretory process. During the dark period, which is the activity and feeding period, there is a decrease in the size of cells and individual zymogen granules as well as in the amount of secretory material. This is paralleled by a drop in the number of ribosomes and Golgi vesicles (after a transient increase) and a loss of cytoplasmic membranes. Most of the cell's zymogen content is refilled during the first hours of the light period, when cellular autophagy reaches maximal values.
Spillover of corporate governance standards in cross-border mergers and acquisitions

In cross-border acquisitions, the differences between the bidder and target corporate governance have an important impact on the takeover returns. We measure the difference in the bidder and target corporate governance (in terms of shareholder, minority shareholder, and creditor orientation) with newly constructed indices. Our country-level corporate governance indices capture the changes in the quality of the national corporate governance regulations over the past 15 years. When the bidder is from a country with a strong shareholder orientation (relative to the target), part of the total synergy value of the takeover may result from the improvement in the governance of the target assets. In full takeovers, the corporate governance regulation of the bidder is imposed on the target (the positive spillover by law hypothesis). In partial takeovers, the improvement in the target corporate governance may occur on voluntary basis (the spillover by control hypothesis). Our empirical analysis corroborates both spillover effects. In contrast, when the bidder is from a country with poorer shareholder protection, the negative spillover by law hypothesis states that the anticipated takeover gains will be lower as the poorer corporate governance regime of the bidder will be imposed on the target. The alternative bootstrapping hypothesis argues that poor-governance bidders voluntarily bootstrap to the better-governance regime of the target. We do find support for this bootstrapping effect.
The danger of misunderstanding ‘culture’

Most conservationists working in Madagascar recognise that if conservation goals are to be achieved, conservation bodies have to work together with, rather than against, local people. One important aspect of this is taking local ‘culture’ into account. However, what is understood by ‘culture’ in such contexts tends to be extremely partial as ‘culture’ is almost always limited to taboos ( fady ). The article discusses the danger of such a narrow view suggesting that ‘culture’ is infinitely more complex and subtle than its immediately apparent surface. I argue that if conservationists’ commitment to take ‘culture’ seriously is genuine, it must also apply to those cultural phenomena that are in conflict with conservation programmes. This applies in particular to rural Malagasy people’s desire to have many descendants; a desire which is linked to their fundamental understanding of what represents a meaningful life. RESUME La plupart de ceux qui travaillent dans des institutions dediees a la protection de la nature se rendent bien compte que s’ils veulent reussir dans leur entreprise ils doivent travailler avec, et non contre, la population locale. Pour cela il est important de tenir compte de la ‘culture’. Neanmoins, ce qu’ils englobent dans le terme ‘culture’ est fort limite et le plus souvent reduit aux seuls tabous ( fady ). L’article considere les dangers qu’une telle limitation implique et demontre que la culture est quelque chose d’infiniment plus complexe et subtile que ce qui apparait en surface. Je ne doute pas de la bonne foi des protecteurs de la nature qui veulent tenir compte de la culture mais je tiens ici a souligner qu’ils doivent aussi accepter l’existence d’aspects culturels qui vont a l’encontre de leur programme, car declarer vouloir travailler avec les habitants ne serait qu’une parade s’il en etait autrement. Mon analyse porte sur l’ensemble des aspects lies au desir d’avoir une progeniture nombreuse pour les populations rurales malgaches. Etre humain consiste avant tout a avoir de bonnes relations et definir une morale entre les membres de generations differentes d’une famille, dans le passe, le present et le futur, car c’est cela que d’avoir une famille. Ces relations sont creees et maintenues de diverses manieres au quotidien et dans la vie rituelle mais plus particulierement au niveau des enfants car ils representent la benediction ancestrale et comme ils relient les vivants et les morts, ils creent le lien entre le passe, le present et l’avenir du groupe de parente. Ainsi si les protecteurs de la nature veulent etre credibles dans leur desir de prendre en compte la ‘culture’ malgache, ils ne peuvent pas limiter leur approche a la reconnaissance de tabous sans reconnaitre d’autres aspects de la culture malgache comme le desir d’avoir une progeniture nombreuse qui ne s’accorde generalement pas avec le programme actuelle de protection de la nature.
Genetic variation and diadromy in some native New Zealand galaxiids (Teleostei: Galaxiidae)

We examined genetic variation at 13 isozyme loci in three diadromous and two non-diadromous species of galaxiid fish from streams in South and Stewart Islands of New Zealand. Analysis of allele frequency data revealed higher Fs7 and Nei's D values among conspecific populations of the non-diadromous species. We propose that the genetic structurings of these species are affected by their migratory behaviours. We suggest that the derived condition of non-diadromous behaviour may increase scope for speciation, but also the probability of extinction. This is exacerbated by population fragmentation over the last century.
EVALUACIÓN DE DOS GENOTIPOS DE CUYES (Cavia porcellus) ALIMENTADOS CON CONCENTRADO Y EXCLUSIÓN DE FORRAJE VERDE

The aim of the study was to evaluate the productive performance and percent of fat in the carcass of two guinea pig(Cavia porcellus) genotypes fed for nine weeks with two types of diets. A Randomized Complete Design with 2x2 factorial arrangements was used: two genotypes (Cieneguilla-UNALM and Peru-INIA) and two diets (diet 1: concentrate supplement, forage and water, and diet 2: concentrate supplement with vitamin C and water). The final body weight, daily weight gain, dry matter intake, feed conversion, carcass weight and yield, and fat and moisture percentage of the carcasses were evaluated. The final body weight, body weight gain, feed conversion and carcass weight at 12 weeks of age in Cieneguilla animals was 1266 g, 15.6 g/day, 3.14 and 878 g respectively whereas in Peru animals was 1154 g, 13.6 g/day, 3.54 and 765 g respectively (p<0.05). The genotype did not affect dry mater intake, carcass yield, or fat and moisture percentage. Moreover, neither the type of diet nor the interaction genotype x diet were significant factors affecting the parameters under evaluation.
The Reading Preferences of Primary School Children in Lahore

The scope of this study aims at investigating reading preferences of children of Lahore city, which is the capital of Punjab province-Pakistan. It was assumed that proper attention towards providing reading opportunities to primary school students (First -Fifth grade) in Pakistan is vital while inculcating reading habits at that tender age. The study was conducted on 300 primary school students. A target group of 300 primary school students was selected for this study. Mainly survey method based on administered questionnaire was used to collect quantitative data from young students. The findings suggested that the children prefer to read locally published printed material in English. Respondents were found interested in reading short stories. (Fiction books, narrating adventure stories remained their favorite. On basis of the findings, the study furnishes suggestions for parents, teachers and school librarians, along with the local publishers for playing their effective role in developing reading habits and addresses the barriers in this regard.
Clostridium acetireducens sp nov, a novel amino acid-oxidizing, acetate-reducing anaerobic bacterium

Strain 30AT (T = type strain), which was isolated from an anaerobic bioreactor fed on waste from a potato starch factory in De Krim, The Netherlands, is a nonmotile, gram-positive, anaerobic, rod-shaped organism that is able to degrade various amino acids, including alanine, leucine, isoleucine, valine, serine, and threonine. Acetate is required as an electron acceptor for the utilization of alanine, valine, leucine, and isoleucine. Other growth substrates, including pyruvate, α-ketobutyrate, α-ketoisocaproate, α-keto-3-methylvalerate, α-ketoisovalerate, and peptone, are intermediates in amino acid catabolism. Strain 30AT utilizes neither the branched-chain amino acids nor alanine via interspecies hydrogen transfer with methanogenic and sulfate-reducing bacteria or via the Stickland reaction with proline or glycine as an electron acceptor. No growth occurs with the following electron acceptors: fumarate, nitrate, nitrite, sulfite, sulfate, and oxygen. Yeast extract is required for growth. Sugars are not degraded. The optimal temperature and optimal pH for growth are 39 to 43°C and 6.4 to 7.6, respectively. The results of a 16S rRNA sequence analysis phylogenetically placed strain 30AT in Clostridium group I (genus Clostridium sensu stricto), where it forms a new and distinct line of descent.
Glycyrrhizic Acid Improves Lipid and Glucose Metabolism in High-Sucrose-Fed Rats

Background: The alarming increase in sugar consumption worldwide has largely contributed towards the escalating symptoms of metabolic syndrome (MetS) such as obesity, insulin resistance and dyslipidaemia. Reduction in lipoprotein lipase (LPL) activity leads to dyslipidaemia, a hallmark of MetS. Increased activation of glucocorticoid receptors also results in symptoms of MetS. Glycyrrhizic acid (GA), a triterpenoid saponin, inhibits 11 β -hydroxysteroid dehydrogenase 1 (11 β -HSD1), which leads to reduced hexose-6-phosphate (H6PDH) activity and decreased glucocorticoids (GCs) production. GCs induce the gene transcriptions of enzymes such as phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase (G6Pase) in the gluconeogenic pathway. Studies have indicated that triterpenoids could act as PPAR agonists and GA is therefore postulated to restore LPL expression in the insulin resistant state. Methods: Twenty-four male Sparague Dawley rats were randomly divided into three treatment groups (Group A, normal diet; Group B, high-sucrose diet; Group C, high-sucrose diet with 100 mg/kg of GA). After 28 days of treatment, the blood samples collected were analyzed for blood glucose, serum insulin and lipid profiles and the tissues collected were used for LPL expression, 11 β -HSD1, H6PDH and PEPCK activities analysis. Statistical analysis was done using REST9 and SPSS softwares, P ≤ 0.05 was considered significant. Results: Oral administration of 100mg/kg GA to high-sucrose induced rats significantly lower blood glucose (32.2%), serum insulin (68.4%), HOMA-IR (81.6%) (P 0.05), with significant upregulation in the liver (2 fold) (P < 0.01). 11s-HSD activity was lower in all tissues in GA treated rats compared to the group on high-sucrose diet alone (P < 0.05). Smaller elevations in H6PDH activities were observed in the liver (14.2%), kidney (7.17%), subcutaneous adipose tissue (SAT) (15.3%), abdominal muscle (AM) (18.4%) and quadriceps femoris (QF) (15.3%). PEPCK activities were elevated in the liver (14.9%) and kidney (7.0%) (P < 0.05) but increased in the SAT (74.4%) and visceral adipose tissues (VAT) (142.0%) (P < 0.01). Smaller increases were observed in the hepatic (61.6%) and renal (47.4%) G6Pase activities (P < 0.05). Conclusion: High-sucrose feeding induced hypertension, hyperglycemia, insulin resistance and dyslipidemia. GA could ameliorate these symptoms by regulating the glucose and lipid metabolism through 11s-HSD1 inhibition and possibly PPAR γ agonism. GA induced LPL expression and contributed towards a postive shift in the lipid profiles. GA also prevented hyperglycaemia and improved insulin sensitivity in the high-sucrose fed rats without causing hypertension. Thus, GA appears to be a possible therapeutic compound in lowering the risks of developing dyslipidaemia and possibly T2DM. doi:10.4021/jem39w
Pathological changes in the small intestine of neonatal calves naturally infected with reo-like virus (rotavirus)

Nine calves, of which six had been challenged with an enteropathogenic strain of Escherichia coli, were found to be naturally infected with rotavirus. Rotavirus was recovered from the faeces of six calves and rotavirus antigen was detected in the intestinal mucosa of all calves. Stunting and fusion of villi were seen principally in the proximal and middle small intestine, where rotavirus antigen was detected by immunofluorescence. Typical lesions of enteric colibacillosis were found in the distal ileum of the challenged calves, associated with adhesion of the challenge strain of E coli to the mucosa. All samples were removed from the intestine under general anaesthesia and denudation of villi was not observed. However, following exsanguination and resampling at the same site in the small intestine of one calf, denudation was a constant feature.
Plant Virology: The Principles

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A simple technique to measure stem respiration using a horizontally oriented soil chamber

This paper introduces a simple technique, the horizontally oriented soil chamber (HOSC), to measure stem and branch respiration easily and accurately. We extend the function of the LI-6400-09 soil CO2 flux chamber by attaching a custom-built polyvinyl chloride (PVC) collar to the stem surface. For small trees and branches we use pipe bushings to connect the chamber to stem surface. Using this technique we measured stem respiration in a young ponderosa pine (Pinus ponderosa Dougl. ex Laws.) plantation in the Sierra Nevada Mountains near Georgetown, Calif. , from June to December 1998. The diurnal and seasonal variations in respiration rate correlate well with the corresponding stem temperature variation. The Q10 values varied from 1.9 to 2.8, which are within the range of Q10 values (1.3-3.3) reported in previous studies. The range of our stem respiration results (3.5-7.2 µmol·m-2·s-1) compares favorably with previous studies on young ponderosa pine trees. This technique provides an alternative to measure s.