Miracle-dz/UniFAR-FTUs huggingface dataset:
Synthesis and Characterization of Hydroxyapatite based on Green Mussel Shells ( Perna viridis ) with Calcination Temperature Variation Using the Precipitation Method

Hydroxyapatite (HA) from green mussel shells (Perna viridis) has been successfully synthesized with a variation of calcination temperature using the precipitation method. Green mussel shells were calcined in a furnace at temperatures of 650°C, 750°C, 850°C and 950°C for 2 h to obtain calcium oxide. AAS results show that the levels of Ca for calcination at temperatures of 650°C, 750°C, 850°C, and 950°C are 30.4333%, 34.3030%, 37.1080% and 49.5757%, respectively. X-Ray diffractometer results show that the crystallization of calcium oxide with calcination at 950°C is high because of its large crystallite size and small microstrain. SEM results reveal some relief lines on the particle surfaces, products of the high temperatures (850°C and 950°C) during calcination. TGA analysis indicates that green mussel shells calcined at 950°C experience a significant weight loss of 22.386%. XRD analysis shows that the HA with a stirring time of 60 min exhibits high crystallinity, with a large crystallite size of (82.50± 5.3) nm and the smallest microstrain value (0.0061). DTA/TGA analysis reveals that HA with a stirring time of 60 min undergoes faster weight loss in the temperature of 426.33°C, with a weight loss of 0.834%. The FTIR spectra show that HA with a stirring time of 60 min shows the functional group of CO3 only at 875.62 cm-1. This indicates that the smples’sCO3 is low. SEM results demonstrate that HA with a stirring time of 60 min has a small agglomerate shape and thick particles structure. EDX analysis reveals that HA with a stirring time of 60 min exhibits a Ca/P molar ratio of 1.67, the Ca/P molar ratio of HA.
Enterprise Risk Management Implementation : The Critical Success Factors For Vietnamese Construction Companies

Construction activities have been faced significant complex and diverse risks, so it is necessary to develop and implement enterprise risk management (ERM) framework for construction organizations. To gain benefits from ERM, identifying the critical success factors of ERM plays an important role. This study aimed to identify critical success factors (CSFs) for implementing ERM in Vietnamese construction company (VCCs), and examine the contribution of CSFs to enterprise’ shareholder value. Using a survey, this research finds that commitment of board and senior management, ERM ownership, training programs, risk management culture, sufficient resources, risk identification, analysis and response and risk communication are define as the most important factors for the effective implementation of ERM in VCCs. Furthermore, by employing both explanatory factor analysis and multiple regression technique to examine the effect of CSFs on enterprises’ shareholder value, the finding reveals that execution and integration, communication and understanding, and leadership or involvement of senior management of ERM have a significantly positive influence on the shareholder value of VCCs. Keywords—Critical success factors, Enterprise risk management, Shareholder value, Vietnamese construction companies
Numerical simulation of flow in open channels with bottom intake racks

A one-dimensional non-hydrostatic flow model is extended to handle practical, while challenging free surface flow problem with a spatially-varied discharge. The proposed model incorporates the effect of curvature of the bed and free surface, in making the pressure distribution non-hydrostatic, and overcomes the accuracy problem of the shallow water equations when simulating spatially varied flow problems that involve non-hydrostatic pressure distribution. Spatially varied flows over bottom racks with bars arranged either parallel to or across the flow, and racks with perforations are considered for assessing the suitability of the model. The predicted global flow characteristics such as residual discharge distributions and flow surface and bed pressure profiles are compared with experimental data for superand sub-critical approach flows. A very good quantitative agreement has been obtained. The predictions of the proposed model are also compared with the results of the shallow water equation. The comparison result reveals the inaccuracy of the hydrostatic pressure approach in modelling spatially varied flow situations where the effects of streamline curvature are significant and essential. The study demonstrates that accurate numerical model can effectively supplement experimental studies in understanding the global flow characteristics of flow over bottom intake racks of various bar shape and opening size.
Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease.

BACKGROUND Sequence variants in the gene encoding estrogen receptor alpha (ER-alpha) may modify the effects of hormone-replacement therapy on levels of high-density lipoprotein (HDL) cholesterol and other outcomes related to estrogen treatment in postmenopausal women. METHODS We characterized 309 women with coronary artery disease who were enrolled in the Estrogen Replacement and Atherosclerosis trial with respect to eight previously described and two newly identified ER-alpha polymorphisms, and we examined the association between these polymorphisms and the response of HDL cholesterol and other lipids to treatment with estrogen alone or estrogen plus progestin. RESULTS After adjustment for age, race, diabetes status, body-mass index, smoking status, alcohol intake, and frequency of exercise, the 18.9 percent of the women who had the IVS1-401 C/C genotype (i.e., with C on both chromosomes in intervening sequence 1 at position 401 before exon 2) had an increase in the HDL cholesterol level with hormone-replacement therapy that was more than twice the increase observed in the other women (13.1 mg per deciliter vs. 6.0 mg per deciliter, P for treatment-by-genotype interaction = 0.004); this effect was limited to changes in the HDL subfraction 3 (HDL3) (P for interaction=0.04). Similar patterns of response were observed for three other highly linked ER-alpha intron 1 polymorphisms close to the IVS1-401 site (range of P values for interaction = 0.07 to 0.005). The pattern of increased response of HDL cholesterol in women with the IVS1-401 C/C genotype was evident in both the women receiving estrogen and those receiving estrogen plus progestin, was preserved across racial and ethnic groups, and was significant among women who were compliant with the study medication (P<0.001). CONCLUSIONS Postmenopausal women with coronary disease who have the ER-alpha IVS1-401 C/C genotype, or several other closely related genotypes, have an augmented response of HDL cholesterol to hormone-replacement therapy.
[A molecular variant of angiotensinogen gene is associated with myocardial infarction in Chinese].

OBJECTIVE A molecular variant of the angiotensinogen(AGT) gene with threonine instead of methionine at position 235(i.e.,with M235T polymor- phism) has been shown to be associated with essential hypertension, preeclampsia, coronary atherosclerosis, coronary heart disease(CHD), myocardial infarction(MI) in Caucasians and in Japanese. The purpose of the present study was to assess whether the M235T polymorphism was associated with MI in a Chinese population. METHODS M235T polymorphism in exon 2 of AGT gene was determined by polymerase chain reaction(PCR) and restriction endonuclease analysis in a study of 57 patients with MI and 76 non-CHD individuals as control. RESULTS The frequencies of T235 allele(0.82) and 235TT genotype (0.70) in the MI group were higher than those in the control subjects(0.63 and 0.42 respectively, P=0.013 and P<0.025). AGT gene 235TT genotype was at significantly increased risk of MI(odds ratio 3.65, P=0.016) in analysis adjusted for several main CHD risk factors. CONCLUSION There is a significant association between AGT gene 235TT genotype and MI, this genotype might be an independent risk for MI in Chinese population.
Physicochemical Analysis of Apis dorsata Honey from Terai Forests , Nepal *

The multifloral honey produced by Apis dorsata from Shahabgunj, Dhakeri, Narayanpur and Perari forest, Nepal, were provided by International Center for Integrated Mountain Development (ICIMOD), Nepal. These ninety nine Apis dorsata honey samples were characterized physicochemical and were found to have values of various quality determining parameters well with in the permissible International standards. The honey samples had pH in the range of 3.8-4.68, free acidity 41-48 meq/kg, lactones 13-16 meq/kg, total acidity 55-65 meq/kg, moisture content 20.5-26%, electrical conductivity 0.22-0.63 mS/cm, proline content 76-160mg/kg, HMF content 30-56mg/kg, diastase number 5.1-29 DN, invertase number 390-499, apparent reducing sugars 73.78-77.78%, fructose 36.93-44.61%, glucose 19.61-27.51% and sucrose 12.07-20.38%.
PaletteViz : Understanding a High-Dimensional Pareto-Optimal DataSet for Multi-Criteria Decision Making AKM

In order to solve mutli/many-objective optimization problems, a large number of efficient algorithms have been proposed. The final outcome of these algorithms is a set of trade-off solutions that span the entire Pareto-optimal front. A subsequent decision-making task must analyze these Pareto-optimal solutions to choose a single preferred solution. This is where an efficient visualization technique makes a significant role in assisting the decision-makers (DM) to understand the high-dimensional Pareto-optimal solutions in terms of relevant information, such as, local and global shapes of the Pareto-optimal surface, spatial distance of one solution to another, a solution’s trade-off among conflicting objectives in its neighborhood, closeness of a solution to constraint boundary, and others. Two and three-dimensional Pareto-optimal fronts are trivial to visualize and allow all the above analysis to be done in a comprehensive manner. However, for four or more objectives, a suitable visualization method that can extract such information is still not available, and innovative methods are long overdue. In this paper, we propose a novel way to map a high-dimensional Pareto-optimal data-set into twoand-half dimensions with features that may be of great interest to DMs. As a proof-of-principle demonstration, we apply our proposed palette visualization (PaletteViz) technique to a number of different structures of Pareto-optimal data-sets and discuss how the proposed technique is different from a few popularly used visualization techniques and how it may be useful in a mutli-criteria decision making tasks.
Tóth A production study on the choice of Hungarian demonstratives

In the case of languages which make a two-way distinction between demonstrative terms the choice between spatial demonstratives has traditionally been assumed to depend on the referent’s physical proximity to the speaker. However, recently this egocentric and speaker-anchored view has been challenged, and the addressee’s role in demonstrative reference has been emphasized (Peeters & Özyürek 2016). This paper reports the results of a production study on the use of Hungarian demonstrative determiners. It is argued that though the traditional view cannot be rejected, it is not satisfactory in itself, i.e. besides relative distance from the speaker the establishment or lack of joint attention between speaker and hearer to the referent and the presence or absence of a pointing gesture are also decisive factors.
Persistent Hypoglycemia in Venlafaxine Overdose

Venlafaxine is a serotonin norepinephrine reuptake inhibitor thought to have little effect on glucose metabolism. However, hypoglycemia in venlafaxine overdose has been described in a paucity of case reports, and we present a unique case of venlafaxine induced hypoglycemia complicated by malnutrition and concomitant alcohol intoxication. A 29-year-old male presented to the emergency department after a venlafaxine XR overdose and concomitant alcohol intoxication. He was admitted to the ICU with serotonin syndrome, found to be hypoglycemic, and started on intravenous dextrose. Despite clinical improvement over a few days, and being reinitiated on an oral diet, the patient’s glucose remained low. 65 hours after ingestion of the venlafaxine, subcutaneous octreotide was administered and the hypoglycemia resolved. We suggest early and repeated measurements of blood glucose in patients presenting to the emergency department and ICU with overdose ingestions, and to maintain a multifactorial approach to the etiology of any resultant hypoglycemia.
On the application of a two-frame particle tracking velocimetry with multi-frame approach

Novel al rithms for three-dimensional particle-tracking velocimetry are proposed and tested with three-dimensional data. The particle identification procedure is modified respect to the traditional background subtraction, local thresholding and grey level weighted averaging by using the Harris matrix. The local maximum of grey levels around a “feature”, which is associated to the particle, is identified and the barycentre is calculated by using Gaussian fitting. The spatial matching procedure, based on the epipolar geometry, is improved by using two subsequent frames, in order to reduce the number of ambiguities. The tracking scheme implements the nearest neighbour cluster matching with a similarity criterion based on a correlation function built between two successive time steps, which depends on the distance and angles of particles surrounding the particle to be track (Ruan and Zhao 2005). The algorithm is enriched with several temporal multi-frame improvements, i.e. extrapolation of expected particle positions in subsequent frames and frame-gap technique.
Conodont biostratigraphy and carbonate microfacies of the Late Devonian to Mississippian Milivojevića Kamenjar section ( Družetić , NW Serbia )

the Balkan Peninsula and little is known about the palaeogeographic relationships between this region and other areas (e.g. South Urals, Central Europe, Southern Europe, Iberian Peninsula, British Islands, North Africa) with well-established zonations based on conodonts (e.g. Sandberg et al. 1978; Corradini 2003, 2008; Kaiser et al. 2009; Corradini et al. 2016, etc.) and ammonoids (e.g. Korn 1996, Korn et al. 2007). The diverse fossil content of the limestone olistolith in the Milivojevića Kamenjar outcrop makes this the best key site for Carboniferous stratigraphy and palaeogeography in the Balkan Peninsula. The fossil site was discovered sixty years ago; the first description of rather diverse ammonoid assemblages from this locality was published by Stevanović & Kullmann (1962). In this monographic article, two fossil horizons were distinguished with a total of twelve ammonoid species. Already in this first description, controversial opinions on the geological setting were expressed (for a review, see Korn et al. 2010a). Ruzhencev & Bogoslovskaya (1971) did already comment on some mistakes in the original taxonomic determinations (of some ammonoid species and genera) and the stratigraphic conclusions drawn from the ammonoid assemblages. Therefore, it became evident that a revision of the stratigraphy (ammonoids and conodonts) and of the whole sedimentary succession is necessary. Following the studies on the ammonoids by Stevanović & Kullmann (1962), investigation of conodonts (Spasov & Filipović 1967, Scharfe 1977, Stojanović-Kuzenko & Pajić in Filipović 1995) and other faunal elements (Filipović 1995) suggested the potential of this section for stratigraphic correlation with other regions. We undertook a new investigation of the Milivojevića Kamenjar outcrop since 2008 by sampling the entire section in terms of ammonoids, conodonts and carbonate microfacies. In this process, we already published a series of papers dealing with the revision of the ammonoids, including a discussion of the stratigraphic age and the palaeogeographic position between Laurussia and Gondwana (Korn & Sudar 2010, 2016; Korn et al. 2010a, b, c, d, 2012).
The Golden Ratio family and the Binet equation

The Golden Ratio can be considered as the first member of a family which can generate a set of generalized Fibonacci sequences. Here we consider some related problems in terms of the Binet form of these sequences, {Fn(a)}, where the sequence of ordinary Fibonacci numbers can be expressed as {Fn(5)} in this notation. A generalized Binet equation can predict all the elements of the Golden Ratio family of sequences. Identities analogous to those of the ordinary Fibonacci sequence are developed as extensions of work by Filipponi, Monzingo and Whitford in The Fibonacci Quarterly, by Horadam and Subba Rao in the Bulletin of the Calcutta Mathematical Society, within the framework of Sloane’s Online Encyclopedia of Interger Sequences.
Ocular Surface, Ocular Adnexal, and Lacrimal Complications Associated With the Use of Systemic 5-Fluorouracil

Purpose To determine the prevalence rates and associated characteristics of patients who have ocular surface, ocular adnexal, and lacrimal complications associated with the systemic use of the cancer chemotherapeutic agent 5-Fluorouracil (5-FU). Methods An exposure-based cohort study was designed. Adult patients who had completed at least 3 months of systemic 5-FU therapy within the past 5 years were eligible for enrollment. Study subjects had a detailed medical history taken with emphasis on preexisting conditions known to be associated with the development of ocular surface, ocular adnexal, and lacrimal complications. An ocular examination was then performed. A complete nasolacrimal system evaluation was performed if symptoms or findings were identified. The prevalence was then determined for each ocular symptom and each ocular finding identified that was not present pretreatment. An exploratory analysis was then performed to identify patient characteristics that might influence the likelihood of developing any of the above complications. Results Fifty-two patients were enrolled in the study. The prevalence rates of the following ocular abnormalities were calculated: ocular irritation, 5.8%; blepharitis, 3.8%; conjunctivitis, 3.8%; keratitis, 3.8%; eyelid dermatitis, 5.8%; cicatricial ectropion, 1.9%; tearing, 26.9%; punctal-canalicular stenosis, 5.8%; and blurred vision, 11.5%. Blacks had tearing at a significantly higher rate when compared with whites (P =0.022, 2-sided Fisher exact test). Three patients had permanent complications that will require surgery for correction. Of the 7 patients who had a single abnormality, 6 had tearing and one had eyelid dermatitis. All of the 8 patients who had multiple findings had tearing as one of their abnormalities. Conclusions Ninety-three percent of the patients who had an ocular abnormality had tearing as one of the complications. Patients who are receiving systemic 5-FU and begin to tear should have an ocular examination, looking for ocular surface, ocular adnexal, and lacrimal complications.
Remodeling of Membrane Lipids in Iron-starved Chlamydomonas*

Background: Iron starvation triggers lipid droplet and triacylglycerol (TAG) accumulation in Chlamydomonas reinhardtii. Results: The overall lipid profile shows a decrease in the absolute content of monogalactosyldiacylglycerol (MGDG) and an increase in saturated and monounsaturated fatty acids. Conclusion: Iron starvation has an early and distinct effect on membrane lipids, before onset of chlorosis. Significance: Iron deficiency affects distribution of lipid type as well as fatty acid profile. Chlamydomonas reinhardtii cells exposed to abiotic stresses (e.g. nitrogen, zinc, or phosphorus deficiency) accumulate triacylglycerols (TAG), which are stored in lipid droplets. Here, we report that iron starvation leads to formation of lipid droplets and accumulation of TAGs. This occurs between 12 and 24 h after the switch to iron-starvation medium. C. reinhardtii cells deprived of iron have more saturated fatty acid (FA), possibly due to the loss of function of FA desaturases, which are iron-requiring enzymes with diiron centers. The abundance of a plastid acyl-ACP desaturase (FAB2) is decreased to the same degree as ferredoxin. Ferredoxin is a substrate of the desaturases and has been previously shown to be a major target of the iron deficiency response. The increase in saturated FA (C16:0 and C18:0) is concomitant with the decrease in unsaturated FA (C16:4, C18:3, or C18:4). This change was gradual for diacylglyceryl-N,N,N-trimethylhomoserine (DGTS) and digalactosyldiacylglycerol (DGDG), whereas the monogalactosyldiacylglycerol (MGDG) FA profile remained stable during the first 12 h, whereas MGDG levels were decreasing over the same period of time. These changes were detectable after only 2 h of iron starvation. On the other hand, DGTS and DGDG contents gradually decreased until a minimum was reached after 24–48 h. RNA-Seq analysis of iron-starved C. reinhardtii cells revealed notable changes in many transcripts coding for enzymes involved in FA metabolism. The mRNA abundances of genes coding for components involved in TAG accumulation (diacylglycerol acyltransferases or major lipid droplet protein) were increased. A more dramatic increase at the transcript level has been observed for many lipases, suggesting that major remodeling of lipid membranes occurs during iron starvation in C. reinhardtii.
Validation of commonly used immunostains on cell‐transferred cytologic specimens

Immunocytochemical staining (ICC) is often limited by the lack of cell blocks that contain diagnostic cells or by the unavailability of smear materials. The cell‐transfer technique, in which original smear material is divided into several pieces and then transferred to multiple slides, can facilitate multiple ICC on limited materials. However the reliability of the staining results has not been systematically evaluated.
Effects of antagonistic fungi and plant growth-promoting rhizobacteria on growth of tomato and reproduction of the root-knot nematode, Meloidogyne incognita

The effects of antagonistic fungi (Paecilomyces lilacinus, Pochonia chlamydosporia and Trichoderma harzianum) and plant growth-promoting rhizobacteria (PGPR), namely Bacillus subtilis, Paenibacillus polymyxa and Burkholderia cepacia, were studied alone and in combination in glasshouse experiments on the growth of tomato and on the reproduction of the nematode Meloidogyne incognita. Application of antagonistic fungi and PGPR caused a significant (P < 0.05) increase in tomato growth (based on shoot dry weight) both with and without nematodes. P. lilacinus was more effective in reducing galling and improving the growth of nematode-inoculated plants than T. harzianum, while P. polymyxa was more effective than B. subtilis. The greatest increase in growth of nematode-inoculated plants and reduction in nematode galling was observed when P. polymyxa was used with P. lilacinus or P. chlamydosporia. P. lilacinus parasitised more females and eggs than the other fungi tested. Root colonisation by P. polymyxa was high when used alone but reduced in the presence of antagonistic fungi.