Miracle-dz/UniFAR-FTUs huggingface dataset:
Maternal lactation characteristics after consumption of an alcoholic soup during the postpartum ‘doing-the-month’ ritual

Abstract Objective The present study examined whether ethanol exposure influences lactation parameters. Specifically, selected constituents in maternal blood and milk and the lactation performance of Chinese lactating mothers were evaluated after they had consumed chicken soup flavoured with sesame oil and rice wine (CSSR), a diet traditionally prescribed during the postpartum ‘doing-the-month’ ritual. Design Twenty-three lactating mothers were examined. Informed consent was obtained from each subject. Each subject was tested on two occasions separated by a week. The target alcohol dosage was 0·3 g/kg body weight. Milk and blood samples were collected prior to consumption of soup and at 120 and 150 min, respectively, after consumption. Levels of various constituents were measured. The time for ejection of the first milk droplet and total milk volume yielded were also measured. Results Consumption of CSSR influenced TAG, insulin and lactate levels in maternal blood. Likewise, consumption of the soup affected milk composition and its nutritional status, particularly total protein, TAG, fatty acid, β-hydroxybutyrate and lactate levels. CSSR intake significantly affected TAG and lactate levels in milk. The time for the first milk droplet to be ejected was significantly longer in the CSSR group, indicating that the milk-ejecting reflex is inhibited. However, blood prolactin level increased slightly after ethanol intake. Milk yields were reduced after ingestion of CSSR although the difference was not statistically significant. Conclusion Consumption of CSSR affects not only the composition of maternal blood and milk, but also lactation performance. These findings suggest that an alcoholic diet should be avoided during lactation.
The retention of dentures.

accurate master casts, final survey and design, education of the patient, insertion and maintenance of the dental prosthesis are a ll of equal importance. M outh preparation may encompass a ll fields of dentistry. The importance of modification of teeth by grinding and polishing, or cast restorations to harmo­ nize w ith the path of insertion of the denture, has been discussed. These modi­ fications should provide the partia l den­ ture w ith adequate support, stability and retention w ith in the physiological lim its of the supporting structures. M od ifica­ tions of the opposing occluding surfaces are indicated to aid in establishing proper occlusion. A removable partial denture made in accordance w ith these principles is not the forerunner of a complete den­ ture, but maintains oral tissues and health. 504 Security National Bank Building
Bag-mask ventilation and direct laryngoscopy versus intubating laryngeal mask airway: a manikin study of hands-on times during cardiopulmonary resuscitation

Objectives The percentage of hands-on time during cardiopulmonary resuscitation is a major determinant of patient outcome. We hypothesized that airway management with the intubating laryngeal mask airway (ILMA) would give greater hands-on time than with bag-mask ventilation (BMV), followed by direct laryngoscopy (DL), particularly in difficult-to-manage airways. Participants and methods Thirty paramedics and 40 medical students performed four standardized, 6-min cardiopulmonary resuscitation scenarios with the SimMan3G in a random sequence. These were normal and difficult-to-manage airways using either BMV+DL or ILMA. Results The time to the first successful ventilation was significantly longer with the ILMA (P<0.001). Hands-on time was lower for the ILMA after 2 min (67±8 vs. 81±8 s for BMV+DL, P<0.001), but was then significantly greater from the third minute onward (115±11 vs. 104±9 s for BMV+DL, P<0.001). The success rate of the first intubation attempt was higher and the time to ET placement was shorter with the ILMA, especially in the difficult-to-manage airway (P<0.001). Conclusion In this manikin-based study, hands-on time was greater with the ILMA than with BMV+DL. The ILMA was particularly useful in increasing hands-on times in the difficult-to-manage airway.
Ageing in a changing place: a qualitative study of neighbourhood exclusion

Abstract An inclusive neighbourhood is a key facilitator enabling older adults to age in place. Neighbourhoods have been identified as a dimension of social exclusion important to older adults, and it has been argued that older adults are particularly vulnerable to neighbourhood change. The aim of this study was to explore older adults’ experiences of neighbourhood exclusion within the context of neighbourhood change. Focus groups were undertaken in the urban and rural areas of a metropolitan borough in England involving a total of 41 older adults, with data analysed via thematic analysis. Urban areas in the borough studied have transformed following the closure of the mining industry, with a high level of deprivation in many areas, while some rural areas have undergone gentrification. Within the context of structural neighbourhood change, four themes were identified: community cohesion, political agency, feelings of safety and the physical environment. The themes were interlinked, which calls for collaboration across traditional lines of professional responsibility, and for research that encompasses different aspects of neighbourhood exclusion. This study contributes with knowledge on older adults’ experiences of exclusion, including novel findings on the importance of political agency and collective memory, and identifies actions to combat exclusion. An active involvement of older adults in the development of initiatives to tackle social exclusion is recommended.
ESCalate Developing Pedagogy and Practice 2009 Grant Project Final Report

Date submitted 25 January 2011 Project Title The CPD (Continuing Professional Development) Needs of Mentors in Post-Compulsory ITT (Initial Teacher Training) Project Leader Dr Ewan Ingleby Institution University of Teesside Partners Hartlepool College of FE, Initial Teacher Training 1. Middlesbrough College, Initial Teacher Training 2. New College Durham, Initial Teacher Training 3. Stockton Riverside College, Initial Teacher Training 4. Project Start date 1 December 2009
Gene Expression Profiling in Schizophrenia and Related Mental Disorders

The etiology and pathophysiology of schizophrenia and related mental disorders such as bipolar disorder and major depression remain largely unclear. Recent advances in mRNA profiling techniques made it possible to perform genome-wide gene expression analysis in a hypothesis-free manner. It was thought that this large-scale data mining approach would reveal unknown molecular cascades involved in mental disorders. Contrary to this initial expectation, however, DNA microarray results in psychiatric fields have been notoriously discordant. Here the authors review the findings of DNA microarray analysis, focusing on systematic gene expression changes in schizophrenia, as well as alterations in the expression of specific genes, that have been reported and replicated. The authors also address the probable causes for the discordance among studies, possible ways to solve the problem, and their preferred approach for data interpretation.
Brachial Plexus in the Pampas Fox (Lycalopex gymnocercus): a Descriptive and Comparative Analysis

Twenty thoracic limbs of ten Lycalopex gymnocercus were dissected to describe origin and distribution of the nerves forming brachial plexuses. The brachial plexus resulted from the connections between the ventral branches of the last three cervical nerves (C6, C7, and C8) and first thoracic nerve (T1). These branches connected the suprascapular, subscapular, axillary, musculocutaneous, radial, median and ulnar nerves to the intrinsic musculature and connected the brachiocephalic, thoracodorsal, lateral thoracic, long thoracic, cranial pectoral and caudal pectoral nerves to the extrinsic musculature. The C7 ventral branches contribute most to the formation of the nerves (62.7%), followed by C8 (58.8%), T1 (40.0%) and C6 (24.6%). Of the 260 nerves dissected, 69.2% resulted from a combination of two or three branches, while only 30.8% originated from a single branch. The origin and innervation area of the pampas fox brachial plexus, in comparison with other domestic and wild species, were most similar to the domestic dog and wild canids from the neotropics. The results of this study can serve as a base for comparative morphofunctional analysis involving this species and development of nerve block techniques. Anat Rec, 300:537–548, 2017. © 2016 Wiley Periodicals, Inc.
An assessment of selected family business values in small and medium-sized family businesses

This study highlights the influence of selected business family values on the success of small and medium-sized family businesses. Success, for the purpose of this study, is measured using two variables, namely Harmonious family relationships and Perceived future continuity . The primary objective of this study is twofold: firstly, to identify the potential influence of selected business family values on the success of family businesses and secondly, to make practical recommendations on actions that families in business can take to ensure harmonious family relationships and the future continuity of their family businesses. The target population of this study was small and medium-sized family businesses in South Africa, and a total of 931 individual questionnaires were returned from 173 family businesses. The data collected was subjected to various statistical analyses, including exploratory factor analysis, calculating Cronbach alpha coefficients, and multiple linear regression analysis. The findings of this study show that the more family members perceive fair treatment in the family business, the more harmonious family relationships and perceptions of business continuity will be. In addition, the perceived level of trust, commitment and effective communication has a positive influence on family harmony and business continuity. This study has added to the empirical body of family business research, and provides an important first step in gaining insights into selected family business values that influence the effective functioning of family businesses.
In vivo magnetic resonance (MR) study of fatty liver: Importance of intracellular ultrastructural alteration for MR tissue parameters change

Fatty liver is thought to have a shorter T1 relaxation time than normal liver tissue, due to the accumulation of triglyceride. Previous studies regarding T1 and T2 relaxation times, however, show widely different results. In order to elucidate the mechanism responsible for the changes and diversity of relaxation times in fatty liver, we created two animal models in 14 rabbits, one acute form (N = 6) and the other chronic form (N = 8). Four rabbits were taken as a control group. Tissue relaxation times and the magnetization transfer (MT) effect of the liver tissue in these two models were measured. The results were correlated with biochemical analysis of water and fat content and histological examination, including findings in light microscopy and electron microscopy. Although the fatty ratio in both forms of fatty liver was similar, their tissue relaxation rate and MT effect were significantly different. The acute form showed prolongation of both T1 and T2 relaxation times (512 ± 51 msec vs. 710 ± 95 msec and 39 ± 1.8 msec vs. 48 ± 3.7 msec, respectively) and a decrease of the MT effect (50 ± 5.1% vs. 38 ± 6.3%), compared to those of the control group and preinduction liver. The chronic form showed shorter T1 and T2 values (526 ± 36 msec vs. 406 ± 56 msec and 36 ± 1.6 msec vs. 33 ± 2.3 msec, respectively) and a stronger MT effect (21 ± 0.9% vs. 26 ± 2.3%). In acute form fatty liver, electron microscopic examination revealed dramatic subcellular changes, such as vesicular transformation, a markedly increased amount of smooth endoplasmic reticulum (SER), and disruption of the crista. These changes were not found in the chronic form fatty liver. From this study, we concluded that the ultrastructural alteration in the subcellular organelles of hepatocyte might play a crucial role for the chameleonic presentation of MR tissue parameters in fatty liver. J. Magn. Reson. Imaging 2001;14:35–41. © 2001 Wiley‐Liss, Inc.
Cognitive Schemas among Mental Health Professionals and Other Health Professionals

Objective: Research has demonstrated that dysfunctional cognitive schemas among mental health professionals (MHPs) may influence the ability to process clients' information in an unbiased manner, may be a substantial source of error in psychotherapeutic ratings, hinder accurate reporting of clients' cognitive schemas, and have a detrimental effect on therapeutic alliance. The present study compared cognitive schemas among MHPs and other health professionals (OHPs). Materials and Method: A sample of 128 professionals (64 MHPs and 64 OHPs) was chosen using a purposive sampling technique. The study used a cross-sectional observational research design. The Young Schema Questionnaire Short Form 3rd version was administered on the consenting participants. Results: OHPs had higher maladaptive schemas on the domains of abandonment and defectiveness. Overall, males had more maladaptive schemas in the domains of abandonment, mistrust, entitlement/superiority, admiration/recognition seeking, and emotional inhibition. Among MHPs, a weak positive correlation of years of experience with vulnerability to harm or illness was seen. Among other health professionals, a significant but weak positive correlation of age with admiration/recognition seeking was seen. Conclusion: This study highlights the presence of maladaptive schemas in health professionals and the need for incorporation of training modules to address these.
Association of Increased Bcl‐2 Expression with Rescue from Tumor Necrosis Factor‐α‐Induced Cell Death in the Oligodendrocyte Cell Line OLN‐93

Abstract: The present study investigated the effects of flupirtine(Katadolon) on tumor necrosis factor (TNF)‐α‐mediated cell death andBcl‐2 expression in the permanent rat oligodendrocyte cell line OLN‐93 (OLNcells). TNF‐α (500 U/ml) induced apoptosis of OLN cells, which wasconfirmed by DNA fragmentation using an in situ end‐labeling technique andultrastructural analysis. Flupirtine significantly reduced the rate ofspontaneous cell death of OLN cells already at low concentrations;TNF‐α‐mediated apoptosis was suppressed only with higher concentrationsof flupirtine (100 μM). Expression of Bcl‐2 protein and mRNA inOLN cells was detected by immunocytochemistry, western blot, and RT‐PCR.Quantitative analysis of western blots revealed an ∼2.5‐fold up‐regulationof Bcl‐2 protein during TNF‐α treatment. Furthermore, addition of 10 or100 μM flupirtine before incubation with TNF‐α led to anapproximately threefold increase of Bcl‐2 expression. Exposure of OLN cells toflupirtine alone moderately augmented the expression of Bcl‐2 protein. Ourdata demonstrate that flupirtine up‐regulates the expression of Bcl‐2 proteinin OLN cells; this Bcl‐2 induction is associated with a reduced rate ofTNF‐α‐induced cell death.
Flexible noncontact electrodes for comfortable monitoring of physiological signals

Physiological signals such as electrocardiography (ECG), electromyography (EMG), and electroencephalography (EEG) could objectively reflect the functioning status of the human body and the monitoring of these signals is useful for various applications including brain computer interface, neurological rehabilitation, and long‐term healthcare monitoring. Currently, wet electrodes are commonly used for the monitoring of physiological signals and it usually requires conductive gels to achieve high quality recordings, which may cause discomfort to the patient and increase risk of skin allergy. In this study, a noncontact electrode made of a multilayer flexible printed circuit without any rigid electronic components on either side was proposed. The flexible noncontact electrode was capable of measuring physiological signals without any direct skin contact or conductive gels and could be bent freely according to the local shape to achieve optimal capacitive coupling with the skin surface. The results showed that the proposed flexible noncontact electrode could obtain different physiological signals with good quality compared with traditional wet electrodes. The ECG signals could be reliably measured with different insulation materials between the skin and the electrode, with up to five layers of insulation materials. It was also found that flexible electrode could achieve higher signal‐to‐noise ratio and therefore had better performance than traditional hard printed circuit board electrode, when measuring EMG signal through the cloth and EEG signals over the hair. The proposed method of this study might provide a novel and comfortable way to measure physiological signals for neurological rehabilitation, wearable devices, and other healthcare applications.
Keratoconus Detection Based on Videokeratoscopic Height Data

Purpose. To develop a videokeratoscopic-based keratoconus detection scheme that avoids the ambiguity of dioptric power definitions and videokeratoscope design. Methods. Corneal height data obtained with a commercial videokeratoscope are decomposed into the set of orthogonal Zernike polynomials. Expansion coefficients of a “normal” group and a keratoconus group are compared to find significant differences. Elevated Zernike terms are used to detect the disease in these populations. The performance of this detection scheme is compared to other videokeratoscopic keratoconus indices. Results. Two low-order Zernike polynomial terms are identified as being elevated in keratoconus patients and combined to form a new detection index. This index performed at least as well as keratoconus detection schemes based on the inferior- superior (I-S) value, the steepest radial axes (SRAX), and the Surface Asymmetry Index (SAI) for the samples studied. Conclusion. The proposed Zernike scheme offers a potentially viable algorithm for detecting keratoconus that avoids the ambiguities of dioptric power definitions and is independent of videokeratoscope design.
2-D magnetic rotational loss of electrical steel at high magnetic flux density

Rotational magnetic loss in magnetic core materials has been examined with respect to the direction of rotation at high magnetic flux density by a newly developed two-dimensional magnetic measurement method. The rotational losses in clockwise or anticlockwise directions depend largely on inclination angle of magnetic filed sensing axis to orthogonal magnetic flux axes. The rotational loss changes first appear at 1.5 T in accordance to the decrease of phase difference between magnetic field H and magnetic flux density B.
Regulation of Mouse Follicle Development by Follicle-Stimulating Hormone in a Three-Dimensional In Vitro Culture System Is Dependent on Follicle Stage and Dose1

Abstract The developmental requirements of ovarian follicles are dependent on the maturation stage of the follicle; in particular, elegant studies with genetic models have indicated that FSH is required for antral, but not preantral, follicle growth and maturation. To elucidate further the role of FSH and other regulatory molecules in preantral follicle development, in vitro culture systems are needed. We employed a biomaterials-based approach to follicle culture, in which follicles were encapsulated within matrices that were tailored to the specific developmental needs of the follicle. This three-dimensional system was used to examine the impact of increasing doses of FSH on follicle development for two-layered secondary (100–130 μm; two layers of granulosa cells surrounding the oocyte) and multilayered secondary (150–180 μm, several layers of granulosa cells surrounding the oocyte) follicles isolated from mice. Two-layered secondary follicles were FSH responsive when cultured in alginate-collagen I matrices, exhibiting FSH dose-dependent increases in follicle growth, lactate production, and steroid secretion. Multilayered secondary follicles were FSH dependent, with follicle survival, growth, steroid secretion, metabolism, and oocyte maturation all regulated by FSH. However, doses greater than 25 mIU/ml of FSH negatively impacted multilayered secondary follicle development (reduced follicle survival). The present results indicate that the hormonal and environmental needs of the follicular complex change during the maturation process. The culture system can be adapted to each stage of development, which will be especially critical for translation to human follicles that have a longer developmental period.
The Cultural Meaning of Children Sleeping Outdoors in Finnish Winter

Purpose: Little is known about children sleeping outdoors in a northern winter climate, although it is a common practice in northern countries. The article describes the cultural meaning of this child care practice from the viewpoint of mothers. Design: Explorative descriptive study design was adopted and unstructured interviews were processed by qualitative content analysis. Participants: Twenty-one mothers of families in northern Finland participated. Results: Family, cultural outdoor sleeping practice and northern winter environment constituted compatibility, which consisted of four generic categories: strengthening family well-being through outdoor sleeping, taking notice of security perspectives, adaptation to the northern winter environment, and cultural knowledge-building processes. Conclusions: Family well-being was strengthened through outdoor sleeping of children when all security perspectives were first taken into account. Families were adapted to the northern winter environment and cultural knowledge was built. A fit was found between families, cultural child care practice, and northern winter environment constituting a coherent whole.