Miracle-dz/UniFAR-FTUs huggingface dataset:
An Analysis of American Academic Libraries Websites: 2000-2010

Purpose – The current study seeks to describe and analyze academic library websites in the years 2000 and 2010, as they appear both in the Internet Archive and in current library websites.Design/methodology/approach – A content analysis of 31 academic libraries homepages which were selected from the ACRL accredited LIS schools was conducted.Findings – Findings reveal that the content of academic library websites in the years 2000 and 2010 has much changed over the ten years, presenting an increasing use of e‐journals and Web 2.0 applications, as well as a focus on library users, and a great use of graphics in websites.Practical implications – The comparison documented in the paper should prove very interesting and important to librarians, information scientists, LIS scholars and students, presenting trends, changes and innovations that have occurred within the scope of academic libraries over the last ten years.Originality/value – This study presents a yet unexplored dimension: the comparison, focusing es.
Nominalization in Asian languages : diachronic and typological perspectives

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Leisure as a Resource for Successful Aging by Older Adults with Chronic Health Conditions

Drawing on the model of Selective Optimization with Compensation (SOC) (Baltes & Baltes, 1990), the purpose of this article is to examine leisure-related goals of older adults with chronic conditions and the strategies they use to not only successfully manage their chronic health conditions but live well with them. Semi-structured in-person interviews were conducted with 18 community-dwelling older adults (nine males, nine females, ages 58–87 years) with a variety of chronic conditions. Inductive and deductive within and cross-case thematic analyses resulted in descriptions of changes and continuity in participants' leisure participation following the onset of their chronic condition and construction of four themes: drawing on existing resources for continued involvement, setting leisure-based goals, using strategies to get more out of life, and more than managing: living a life of meaning. Implications for promoting successful aging are discussed, specifically the benefits of incorporating information and skill-building to help older adults recognize that leisure can be a resource for healthy aging and self-managing their chronic health condition.
Corneal Densitometry in Keratoconus

Purpose: The aim of this study was to compare corneal densitometry measured by Scheimpflug tomography in normal and keratoconic eyes and to assess the differences in densitometry values among the stages of keratoconus. Methods: Keratoconic and normal corneas were examined using the Pentacam. Corneal densitometry was measured over a 12-mm diameter area, divided by annular concentric zones and depths. Keratoconus was classified according to the topographic keratoconus classification. Results: We enrolled 1 eye randomly selected from each of 172 patients with normal corneas (N) and 98 patients with bilateral keratoconus (KC). There were significant differences between the groups for densitometry measurements in 2 annuli: central 2.0 mm in diameter (N = 16.85 ± 2.42, KC = 18.93 ± 2.78, P = 0.0001) and annulus 2.0 to 6.0 mm in diameter (N = 15.18 ± 2.18, KC = 16.16 ± 1.71, P = 0.005), and total diameter (N = 24.89 ± 6.18, KC = 16.71 ± 2.3, P = 0.033). Divided by layers, the inner parts of anterior (120 &mgr;m), central (from 120 &mgr;m to the last 60 &mgr;m), and posterior (last 60 &mgr;m) layers were also higher in the KC group (P < 0.001). There were differences according to the stages of KC for corneal densitometry of the central annuli at total thickness, anterior and central layers. More advanced cases presented a higher backscatter (P < 0.05). The anterior layer presented the smallest overlap between groups and KC stages. Conclusions: The densitometry map reveals that light backscatter was higher in the central portion of the anterior keratoconic cornea than in the normal cornea. The densitometry level is higher in more advanced stages.
Length–mass relationships for adult aquatic and terrestrial invertebrates in a California watershed

We collected 541 invertebrate specimens in riparian and upland habitats of the South Fork (SF) Eel River, California, USA, representing 12 orders and 55 families, and including adults of both aquatic and terrestrial origin. We fitted a power function to this data set at 4 taxonomic levels: 1) the entire pooled sample, 2) composite samples of aquatic and terrestrial taxa, 3) individual orders, and 4) individual families for which there were adequate data (n > 8; 24 families). Coefficients of determination (R2) for length–mass relationships generally increased with increasing taxonomic specificity. Composite samples of aquatic and terrestrial taxa had significantly different length–mass relationships, with dry mass increasing faster with length in terrestrial taxa. Differences in length–dry mass relationships between aquatic and terrestrial taxa appeared to result from significantly higher slopes for terrestrial taxa in length–width relationships, and significantly lower slopes in length–water content relationships. Our results suggest that the use of terrestrial regressions to estimate aquatic insect biomass flux in riparian habitats overestimates both the absolute magnitude of biomass flux as well as its relative importance to insect standing stocks. Development of unique regression algorithms for adult aquatic insect taxa increases the accuracy of aquatic insect biomass estimates in terrestrial habitats.
WITHIN‐ AND BETWEEN‐GENERATION EFFECTS OF TEMPERATURE ON THE MORPHOLOGY AND PHYSIOLOGY OF DROSOPHILA MELANOGASTER

We investigated the effects of developmental and parental temperatures on several physiological and morphological traits of adult Drosophila melanogaster. Flies for the parental generation were raised at either low or moderate temperature (18°C or 25°C) and then mated in the four possible sex‐by‐parental temperature crosses. Their offspring were raised at either 18°C or 25°C and then scored as adults for morphological (dry body mass, wing size, and abdominal melanization [females only]), physiological (knock‐down temperature, and thermal dependence of walking speed), and life history (egg size) traits. The experiment was replicated, and the factorial design allows us to determine whether and how paternal, maternal, and developmental temperatures (as well as offspring sex) influence the various traits. Sex and developmental temperature had major effects on all traits. Females had larger bodies and wings, higher knock‐down temperatures, and slower speeds (but similar shaped performance curves) than males. Development at 25°C (versus at 18°C) increased knock‐down temperature, increased maximal speed and thermal performance breadth, decreased the optimal temperature for walking, decreased body mass and wing size, reduced abdominal melanization, and reduced egg size. Parental temperatures influenced a few traits, but the effects were generally small relative to those of sex or developmental temperature. Flies whose mother had been raised at 25°C (versus at 18°C) had slightly higher knock‐down temperature and smaller body mass. Flies whose father had been raised at 25°C had relatively longer wings. The effects of paternal, maternal, and developmental temperatures sometimes differed in direction. The existence of significant within‐ and between‐generation effects suggests that comparative studies need to standardize thermal environments for at least two generations, that attempts to estimate “field” heritabilities may be unreliable for some traits, and that predictions of short‐term evolutionary responses to selection will be difficult.
Comparative Methods as a Statistical Fix: The Dangers of Ignoring an Evolutionary Model

Comparative methods are widely used in ecology and evolution. The most frequently used comparative methods are based on an explicit evolutionary model. However, recent approaches have been popularized that are without an evolutionary basis or an underlying null model. Here we highlight the limitations of such techniques in comparative analyses by using simulations to compare two commonly used comparative methods with and without evolutionary basis, respectively: generalized least squares (GLS) and phylogenetic eigenvector regression (PVR). We find that GLS methods are more efficient at estimating model parameters and produce lower variance in parameter estimates, lower phylogenetic signal in residuals, and lower Type I error rates than PVR methods. These results can very likely be generalized to eigenvector methods that control for space and both space and phylogeny. We highlight that GLS methods can be adapted in numerous ways and that the variance structure used in these models can be flexibly optimized to each data set.
Effect of caudal clonidine on emergence agitation and postoperative analgesia after sevoflurane anaesthesia in children: Randomised comparison of two doses

Background and Aims: Sevoflurane, a popular inhalational anaesthetic for children, has been associated with significant emergence agitation in the recovery phase. This study was intended to compare two doses of caudal clonidine added to ropivacaine 0.2% in order to decide on the optimal dose for prevention of sevoflurane induced emergence agitation (EA) and to get a meaningful prolongation of postoperative analgesia with minimal side effects. Methods: Sixty-one children aged 1-7 years (American Society of Anaesthesiologists physical status I-II) received standardized general anaesthesia with inhaled sevoflurane and caudal epidural block with 0.2% ropivacaine 1 ml/kg for sub-umbilical surgeries. They were assigned randomly to two groups: (I) clonidine 1 μg/kg added to caudal ropivacaine; (II) clonidine 2 μg/kg added to caudal ropivacaine. EA and postoperative analgesia were assessed using pain/discomfort scale score and face, legs, activity, cry, consolability (FLACC) score respectively. Results: EA was observed in 8 children (26.6%) in group I when compared to only 2 children (6.4%) in group II after first 15 min postoperatively. Incidences of EA at 15 min, as well as total incidence of agitation, were both significantly lower in group II when compared to group I with P < 0.05. Duration of analgesia in group I (12 [8-20] h) and group II (16 [8-20] h) was statistically comparable (P > 0.05). There was no difference in the incidence of sedation or complications. Conclusion: Caudal clonidine 2 μg/kg added to 0.2% ropivacaine 1 ml/kg is suggested to be the optimal dose, for prevention of EA and meaningful prolongation of postoperative analgesia with minimal side-effects.
Transformational Leadership as a Critical Success Factor for Enterprise Resource Planning System Implementation

The successful implementation of an enterprise resource planning (ERP) system has been described as a challenging strategic initiative for many organizations in varied business settings and different organizational cul-tures. During the past two decades, there has been massive investment in adopting ERP system, in addition to a substantial increase in focusing on the importance of users’ acceptance of utilizing such technological technique. Despite the many advantages of successful installing of ERP system demonstrated in literature but still the failure rate of ERP projects is re-markably high. Leaders of ERP implementation projects have the challenge of displaying effective leadership skills and traits to justify strategic and operational decisions taken during implementation of ERP system. To provide better understanding of what may positively influence a successful implementation of ERP system, this research study is an attempt to inves-tigate whether leadership style especially transformational leadership has a significant impact on successful implementation of ERP systems. The theory of transformational and transactional leadership was the foundations for the researched leadership style in this study. A quantitative, non-experimental correlational empirical research strategy examined the degree of significance of the direct relationship between the independent variable of transformational leadership style and the dependent variable, perceived as ERP success. Projects’ leaders, executives, information technology, business managers, and end users who involved in adopting and using ERP system within their Egyptian organizations representing various business settings, were the targeted population of this research. Structural Equation Modeling (SEM) was conducted to test the research hypotheses and analyze the findings and results. The results of the study supported the existence of a significant relationship between transformational leadership style and successful implementation of ERP system.
Randomized phase II study of oxaliplatin and S-1 (OS) versus oxaliplatin and capecitabine (XELOX) in patients with advanced or recurrent colorectal cancer.

595 Background: Combination oxaliplatin and S-1 or oxaliplatin and capecitabine chemotherapy have shown significant efficacy in advanced colorectal cancer. To evaluate those efficacy and safety, we performed a randomized phase II study in patients with metastatic or recurrent colorectal cancer. METHODS Eligible patients were those who had measurable lesions and had no previous history of chemotherapy except adjuvant chemotherapy. The patients of age greater than 18 were enrolled to this study. Oxaliplatin 130 mg/m2 was administered intravenously on day 1 and S-1 80 mg/m2 (OS, Arm A) or capecitabine 2,000 mg/m2 (XELOX, Arm B) was administered orally on days 1-14. Cycles were repeated every 21 days. Patients were treated until proved to have disease progression or unacceptable toxicity. The primary endpoint of the study was to assess the overall response rate (ORR). RESULTS Eight-two patients (male/ female 57/ 31; median age 67, range 29-83; median ECOG PS 1; Arm A/ B 43/45) were enrolled to this study. Twenty-five patients had recurred cancer after surgery and 63 patients were diagnosed as metastatic diseases. A total of 268 cycles (median 5, range 1-34) in Arm A; 278 cycles (median 5, range 1-18) in Arm B were administered. Eighty-two (41 for each arm) patients were evaluated for toxicity and response. The main toxicities were thrombocytopenia [grade 1/ 2/ 3/ 4 = 11/ 7/ 6/ 1 patients (A); 9/ 10/ 7/ 5 (B)], neutropenia [grade 1/ 2/ 3/ 4 = 8/ 6/ 1/ 0 (A); 9/ 9/ 5/ 2 (B)], anemia [grade 1/ 2/ 3/ 4 = 21/ 13/ 3/ 1 (A); 20/ 10/ 3/ 0 (B)], peripheral neuropathy [grade 1/ 2/ 3 = 11/ 8/ 0 (A); 10/ 8/ 2 (B)], and hand-foot syndrome [grade 1/ 2/ /3 = 2/ 0/ 0 (A); 7/ 1/ 2 (B)]. There were 3 CR, 10 PR, 27 SD and 1 PD (A); 3 CR, 15 PR, 17 SD and 6 PD (B). The confirmed ORR in the intention-to-treat population was 30.2 (95% CI: 16.5-43.9) % (A); 40.0 (95% CI, 25.7-54.3) % (B). The median time to progression was 6.6 (95% CI, 4.4-8.8) months (A); 8.1 (95% CI, 6.3-10.0) months (B). The median survival time was 19.0 (95% CI, 7.3-30.8) months (A); 22.0 (95% CI, 12.1-32.0) months in (B). CONCLUSIONS These data suggest that both OS and XELOX regimen are active and are well tolerated regimens in patients with advanced colorectal cancer.
Impact of growth hormone and dehydroepiandrosterone on protein metabolism in glucocorticoid-treated patients.

CONTEXT Chronic pharmacological glucocorticoid (GC) use causes substantial morbidity from protein wasting. GH and androgens are anabolic agents that may potentially reverse GC-induced protein loss. OBJECTIVE Our objective was to assess the effect of GH and dehydroepiandrosterone (DHEA) on protein metabolism in subjects on long-term GC therapy. DESIGN This was an open, stepwise GH dose-finding study (study 1), followed by a randomized cross-over intervention study (study 2). SETTING The studies were performed at a clinical research facility. PATIENTS AND INTERVENTION In study 1, six subjects (age 69+/-4 yr) treated with long-term (>6 months) GCs (prednisone dose 8.3+/-0.8 mg/d) were studied before and after two sequential GH doses (0.8 and 1.6 mg/d) for 2 wk each. In study 2, 10 women (age 71+/-3 yr) treated with long-term GCs (prednisone dose 5.4+/-0.5 mg/d) were studied at baseline and after 2-wk treatment with GH 0.8 mg/d, DHEA 50 mg/d, or GH and DHEA (combination treatment). MAIN OUTCOME MEASURE Changes in whole body protein metabolism were assessed using a 3-h primed constant infusion of 1-[13C]leucine, from which rates of leucine appearance, leucine oxidation, and leucine incorporation into protein were estimated. RESULTS In study 1, GH 0.8 and 1.6 mg/d significantly reduced leucine oxidation by 19% (P=0.03) and 31% (P=0.02), and increased leucine incorporation into protein by 10% (P=0.13) and 19% (P=0.04), respectively. The lower GH dose did not cause hyperglycemia, whereas GH 1.6 mg/d resulted in fasting hyperglycemia in two of six subjects. In study 2, DHEA did not significantly change leucine metabolism alone or when combined with GH. Blood glucose was not affected by DHEA. CONCLUSION GH, at a modest supraphysiological dose of 0.8 mg/d, induces protein anabolism in chronic GC users without causing diabetes. DHEA 50 mg/d does not enhance the effect of GH. GH may safely prevent or reverse protein loss induced by chronic GC therapy.
Inhibitory effects of cAMP and protein kinase C on meiotic maturation and MAP kinase phosphorylation in porcine oocytes

The regulation of MAP kinase phosphorylation by cAMP and protein kinase C (PKC) modulators during pig oocyte maturation was studied by Western immunoblotting. We showed that both forskolin and IBMX inhibited MAP kinase phosphorylation and meiosis resumption in a dose‐dependent manner, and this inhibitory effect was overcome by the protein phosphatase inhibitor, okadaic acid. Pharmacological PKC activator phorbol myristate acetate or physiological PKC activator diC8 also delayed MAP kinase phosphorylation and meiosis resumption, and their effect was abrogated by PKC inhibitors, staurosporine, and calphostin C. The results suggest that meiotic resumption is inhibited by elevation of cAMP or delayed by activation of PKC probably via down‐regulation of MAP kinase activation, which is mediated by protein phosphatase, during pig oocyte maturation. Mol. Reprod. Dev. 63: 480–487, 2002. © 2002 Wiley‐Liss, Inc.
Gene expression in response to endoplasmic reticulum stress in Arabidopsis thaliana

Eukaryotic cells respond to the accumulation of unfolded proteins in the endoplasmic reticulum (ER). In this case, so‐called unfolded protein response (UPR) genes are induced. We determined the transcriptional expression of Arabidopsis thaliana UPR genes by fluid microarray analysis of tunicamycin‐treated plantlets. Two hundred and fifteen up‐regulated genes and 17 down‐regulated ones were identified. These genes were reanalyzed with functional DNA microarrays, using DNA fragments cloned through fluid microarray analysis. Finally, 36 up‐regulated and two down‐regulated genes were recognized as UPR genes. Among them, the up‐regulation of genes related to protein degradation (HRD1, SEL‐1L/HRD3 and DER1), regulation of translation (P58IPK), and apoptosis (BAX inhibitor‐1) was reconfirmed by real‐time reverse transcriptase‐PCR. The induction of SEL‐1L protein in an Arabidopsis membrane fraction on tunicamycin‐treatment was demonstrated. Phosphorylation of initiation factor‐2α, which was inhibited by P58IPK, was decreased in tunicamycin‐treated plantlets. However, regulatory changes in translation caused by ER stress were not detected in Arabidopsis. Plant cells appeared to have a strategy for overcoming ER stress through enhancement of protein folding activity, degradation of unfolded proteins, and regulation of apoptosis, but not regulation of translation.
Analisis Pengaruh Tingkat Kekayaan Daerah, Belanja Daerah, Ukuran Pemerintah Daerah, Leverage Dan Intergovernmental Revenue Terhadap Kinerja Keuangan Pemerintah Daerah(Studi Empiris Pada Pemerintah Daerah/Kota Se-Jawa Tengah 2011-2013)

The local government is required to produce a good financial performance so that people can assess government performance. This study aimed to analyze the influence of the local assets level , local purchase, the size of local governments, leverage and intergovernmental revenue on the financial performance of local governments. This study data using secondary data, financial reports of local governments / municipalities in Central Java in 2011-2013 have been published in www.djpk. kemenkeu.go. id. The sampling method was done by using purposive sampling. The sample in this study as many as 60 districts / cities during 2011-2013. This study uses multiple linear regression analysis model. The results showed that the local purchase and the size of local government are factors that affect the financial performance of local governments. While the level of local assets, leverage, and intergovernmental revenue has no effect on the financial performance of local governments.
Family Influence in Maltese Listed Companies: The Implications on Corporate Governance

The Maltese market is and has always been, dominated by Family Businesses (FB) to the extent that such entities are vital to the resilience of our economy. There tends to be the presupposition that as soon as FBs convert to a public listing, they start implementing rational governance mechanisms, contrasting with the "non-rational behaviour" which is normally associated with the dynamics of running an FB. With this study the authors focus on equity-listed Maltese companies on the Malta Stock Exchange (MSE) and aim to build an understanding on the current situation of such entities’ GC structures to possibly conclude on whether Maltese LFBs are taking the initiative to apply appropriate governance measures which meet their strategic needs, even though there are no obligatory regulations or recommendations on the matter. Moreover, they will shed light on (i) the characteristics of LFBs; (ii) the family governance structures (‘FGS’) in such companies including the role of family institutions as well as the family influence on executive appointments and top positions; and (iii) recommend regulatory and other improvements. Authors carried out semi-structured with 18 participants in charge of corporate governance in Maltese listed companies (MLCs) and conclude that Maltese LFBs do not as yet acknowledge the significance of their distinctive features and the implications of such features on their CG structures. As a result, the application of specific structures related to FBs, in particular, the family constitution and the family institutions are as yet not to be found.
Seismo-ionosphere detection by underground SQUID in low-noise environment in LSBB-Rustrel, France

The permanent operation of a 3 axes magnetometer in the LSBB below 550 m of calcite rock is a unique system of magnetic observation: a rejection rate better than 3 fT/Hz over 40 Hz. The observation of magneto-ionosphere responses to wave emissions both at the epicentre and at their arrival at LSBB for earthquakes of magnitude larger than 3 is reported. A simple model predicts the starting time of these events. These results are compared with those provided by Doppler sounders for ionosphere responses to Rayleigh waves.