Miracle-dz/UniFAR-FTUs huggingface dataset:
Synthesis of Mo2C and W2C Nanoparticle Electrocatalysts for the Efficient Hydrogen Evolution Reaction in Alkali and Acid Electrolytes

The synthesis of low cost, high efficacy, and durable hydrogen evolution electrocatalysts from the non-noble metal group is a major challenge. Herein, we establish a simple and inexpensive chemical reduction method for producing molybdenum carbide (Mo2C) and tungsten carbide (W2C) nanoparticles that are efficient electrocatalysts in alkali and acid electrolytes for hydrogen evolution reactions (HER). Mo2C exhibits outstanding electrocatalytic behavior with an overpotential of −134 mV in acid medium and of −116 mV in alkaline medium, while W2C nanoparticles require an overpotential of −173 mV in acidic medium and −130 mV in alkaline medium to attain a current density of 10 mA cm−2. The observed results prove the capability of high- and low-pH active electrocatalysts of Mo2C and W2C nanoparticles to be efficient systems for hydrogen production through HER water electrolysis.
Haematopoietic Stem Cell Transplantation for Primary Haemophagocytic Lymphohistiocytosis

Haematopoietic stem cell transplantation currently remains the only curative treatment of primary forms of haemophagocytic lymphohistiocytosis (HLH). Rapid diagnosis, efficient primary treatment of hyperinflammation, and conditioning regimens tailored to this demanding condition have substantially improved prognosis in the past 40 years. However, refractory hyperinflammation, central nervous system (CNS) involvement, unavailability of matched donors, susceptibility to conditioning-related toxicities, and a high frequency of mixed chimaerism remain a challenge in a substantial proportion of patients. Gene therapeutic approaches for several genetic defects of primary HLH are being developed at pre-clinical and translational levels.
An Update on the Multifaceted Roles of STAT3 in the Heart

Signal transducer and activator of transcription 3 (STAT3) is a signaling molecule and transcription factor that plays important protective roles in the heart. The protection mediated by STAT3 is attributed to its genomic actions as a transcription factor and other non-genomic roles targeting mitochondrial function and autophagy. As a transcription factor, STAT3 upregulates genes that are anti-oxidative, anti-apoptotic, and pro-angiogenic, but suppresses anti-inflammatory and anti-fibrotic genes. Its suppressive effects on gene expression are achieved through competing with other transcription factors or cofactors. STAT3 is also linked to the modification of mRNA expression profiles in cardiac cells by inhibiting or inducing miRNA. In addition to these genomic roles, STAT3 is suggested to function protectively in mitochondria, where it regulates ROS production, in part by regulating the activities of the electron transport chain complexes, although our recent evidence calls this role into question. Nonetheless, STAT3 is a key player known to be activated in the cardioprotective ischemic conditioning protocols. Through these varied roles, STAT3 participates in various mechanisms that contribute to cardioprotection against different heart pathologies, including myocardial infarction, hypertrophy, diabetic cardiomyopathy, and peripartum cardiomyopathy. Understanding how STAT3 is involved in the protective mechanisms against these different cardiac pathologies could lead to novel therapeutic strategies to treat them.
Genetic Connectivity of the Sky Emperor, Lethrinus mahsena Populations Across a Gradient of Exploitation Rates in Coastal Kenya

Marine-protected areas (MPAs) have the potential to enhance fisheries through transport of larvae or by a net emigration of adult and juvenile fish to adjacent fished areas. A network of appropriately located MPAs will have the potential to reseed fished areas and other MPAs. Connectivity studies are therefore important to assess the effectiveness of a network of MPAs and to determine the spatial scale necessary for spillover effects. The principal aim of this study was to determine the potential for Kenyan MPAs to reseed adjacent fishing zones by evaluating the levels of genetic differentiation of populations of Lethrinus mahsena, a commercially important fish, along a continuum of protected and nonprotected sites. Fish samples were collected from MPAs (Mombasa and Kisite Mpunguti Marine Parks) and the fished reserves adjacent to the two MPAs. Total length and weight of the fish from the sites and fin clips from one of the pectoral fins were collected and preserved in 90% ethanol. Genomic profiles for each sample were obtained through genotyping by sequencing using diversity array technology markers. Results from population structure, diversity, and admixture analyses indicated very low genetic differentiation (F ST = 0.00184, P > 0.05) and low population substructure between samples obtained from the study locations implying a free exchange of fish across protected and nonprotected sites. There was a high gene flow and multidirectional migration rate among the sampling sites. Inbreeding was moderately high (F IS = 0.15, P < 0.05) in the marine parks, indicating high relatedness and probably limited mating options for the species due to small population size or spatial restriction. The lack of genetic differentiation between protected areas and open fishing grounds is indicative of genetic connectivity for the sky emperor. This reinforces the significance of maintaining protected areas to serve as breeding and spawning grounds of fish without adversely affecting the livelihoods of communities that depend on the various fisheries linked to MPAs.
Confirmation of a Two-Factor Solution to the Questionnaire of Cognitive and Affective Empathy in a French Population of Patients With Schizophrenia Spectrum Disorders

The Questionnaire of Cognitive and Affective Empathy (QCAE) is a tool for self-assessing the cognitive and emotional components of empathy. A study showed that a two-factor model fits the data of patients with schizophrenia, whereas other reports on healthy subjects have suggested a five-factor decomposition. We aimed to replicate the model of Horan et al. in a French population with schizophrenia spectrum disorders (i.e., schizophrenia and schizoaffective disorders) participating in the EVACO Study (NCT02901015). In total, 133 patients were assessed with the QCAE, the Positive and Negative Symptom Scale (PANSS), the Personal and Social Performance Scale (PSP), and the Self rating Quality of Life Scale (S-QoL). The two-factor model demonstrated an adequate fit with the data, comparable to that reported by Horan et al. Males scored higher on the Affective subscore than females. After correction for multiple tests, psychopathology (PANSS) and functioning (PSP) did not correlate significantly with the QCAE subscores. However, quality of life (S-QoL) correlated positively with the Emotional Contagion subscore. Thus, the variability of empathetic disposition in schizophrenia may be considered through the cognitive versus affective dichotomy and properly investigated with the QCAE. The results support further investigation of the relationship between QCAE scores and subjective outcome measurements, such as quality of life, and emphasize the importance of cross-cultural comparisons.
A Case–Control Seroprevalence Study on the Association Between Toxoplasma gondii Infection and Bipolar Disorder

Background and Aims: Infection with the parasite Toxoplasma gondii has been associated with bipolar disorder in several countries other than Mexico. Therefore, we sought to determine the association between seropositivity to T. gondii and bipolar disorder in a Mexican population. Methods: We performed an age- and gender-matched case–control study of 66 patients with bipolar disorder (WHO International Classification of Diseases, 10th Revision code: F31) and 396 subjects without this disorder from the general population. Anti-Toxoplasma immunoglobulin G (IgG) and IgM antibodies were determined using commercially available enzyme-linked immunoassays. Results: Six (9.1%) of the 66 patients with bipolar disorder and 22 (5.6%) of the 396 controls had anti–T. gondii IgG antibodies (odds ratio [OR] = 1.7; 95% confidence interval [CI] = 0.66–4.36; P = 0.26). Stratification by gender and age did not show a difference in seroprevalence between cases and controls. The frequency of high (> 150 international units/ml) anti–T. gondii IgG levels was similar in cases (n = 2) and in controls (n = 12) (OR = 1.0; 95% CI = 0.21–4.57; P = 1.00). Stratification by International Classification of Diseases, 10th Revision F31 codes showed that patients with F31.3 code had a higher seroprevalence of T. gondii infection than their age- and gender-matched controls (OR = 16.4; 95% CI = 1.25–215.09; P = 0.04). None of the six anti–T. gondii IgG–seropositive patients with bipolar disorder and 4 (18.2%) of the 22 anti–T. gondii IgG–seropositive controls had anti–T. gondii IgM antibodies (P = 0.54). Conclusions: Our results suggest that T. gondii seropositivity is not associated with bipolar disorder in general. However, a specific type of bipolar disorder (F31.3) might be associated with T. gondii seropositivity. Further research to elucidate the role of T. gondii infection in bipolar disorder is needed.
Father Involvement and Cognitive Development in Early and Middle Childhood: A Systematic Review

This systematic review aims to examine the existing literature concerning the association between father involvement and the development children's cognitive skills during early and middle childhood. Specifically, it analyzes: (1) how the number of researches developed across years; (2) which are the main socio-demographic characteristics of the samples; (3) which are the main focuses examined; and (4) which operational definitions were used to assess father involvement and children cognitive skills. Following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, the articles were searched through PubMed and EBSCO (PsycInfo, PsycArticles, Education Source, Social Sciences Abstract, Family Studies Abstracts, Gender Studies Database and CINAHL complete). The findings suggest that, although each research used a different operational definition of the father involvement construct, in recent years there was a wide and constant interest increase about this issue. Most of the empirical studies utilized quantitative methods, whereas relatively few used qualitative and only one mixed methods. As regards the analysis of socio-demographic characteristics of the samples there is a great evidence that most of them included biological and residential fathers: it may reflect that this type of sample is easier to recruit than non-residential and non-biological fathers. Regarding the socio-economic status and the ethnicity of families, the data highlighted how in recent years the literature on father involvement is starting to look at differences in ethnic and cultural backgrounds, in contrast to past researches. The findings revealed that the main focus is the impact of father involvement on children's cognitive skills and the most of the studies highlighted that it is positive and statistically significant. Regarding to the assessment of father involvement and children's cognitive skills, the literature is quite heterogeneous
Upregulation of IBSP Expression Predicts Poor Prognosis in Patients With Esophageal Squamous Cell Carcinoma

Esophageal squamous cell carcinoma (ESCC), which is characterized by invasiveness and poor prognosis, is the sixth most common leading cause of cancer-related death worldwide. Despite advances in multimodality therapy, ESCC mortality remains high, and an understanding of the molecular changes that lead to ESCC development and progression remains limited. In the present study, Integrin Binding Sialoprotein (IBSP) upregulation was found in 182 of 269 (67.7%) primary ESCC cells at the mRNA level by quantitative real-time polymerase chain reaction (qRT-PCR). Additionally, IHC staining further demonstrated that IBSP was upregulated in ESCC patients and IBSP protein upregulation was significantly related to the lymph node metastasis (P = 0.017), clinicopathologic stage (P = 0.001) and poor disease survival (P = 0.002). Moreover, functional studies illustrated that the IBSP gene can promote the proliferation and metastasis of ESCC cells. Furthermore, IBSP was found to regulate epithelial-mesenchymal transition (EMT), which promotes tumor cell metastasis. In conclusion, our study suggests that IBSP may be a valuable prognostic marker for ESCC patients.
Information Needs for SAFe Teams and Release Train Management: A Design Science Research Study

Large, embedded software development companies increasingly often transform from V-model development to Agile practices, as they want to increase their customer responsiveness. Their teams transform and they are faced with the new challenges on how to measure progress, quality and scope over time. Their management evolve and need new kinds of dashboards to address their information need and ease decision formulation processes. The goal of this paper is to identify the set of measures and indicators important for Agile embedded software development based on SAFe. We studied a large automotive company and identified the information needs of their teams and SAFe release train management. The results show that the three main areas to monitor are: scope creep, defects carried over to integration and integration status. Based on the results of our work, some of the elicited information needs and measures were implemented in forms of dashboards (which we present in the paper). By comparing to the existing literature, we concluded that the set of measures prescribed by SAFe is not sufficient in practice and needs measures relating to scope creep, defects carried over to integration and integration status.
Simülasyon Yöntemine İlişkin Hemşirelik Öğrencilerinin Görüşleri

Amac: Calisma, hemsirelik ogrencilerin senaryo/bilgisayarli simulasyon yonteminin beceri egitiminde kullanimina iliskin goruslerinin belirlenmesi amaciyla yapilmistir. Gerec ve Yontem: Calismada yari yapila ndirilmis alti soruyu iceren odak grup gorusme yontemi kullanilmistir. Orneklem grubuna bir hemsirelik okulunun 2. sinif lisans ogrencilerinden 24 gonullu ogrenci secilmis ve her grupta 8 ogrenci olmak uzere toplam 3 odak grup gorusmesi yapilmistir. Bulgular: Ogrencilerin cogunlugu klinik ortama cikmadan once olusturulan laboratuar ve dershane ortaminda verilen beceri gelistirme uygulamalarinin kendilerine yararli oldugunu ifade etmislerdir. Ancak ogrenciler beceri gelistirme alanlarinda bulunan maketlerin eski ve programlanamayan modelde olmasi ve maketlerin ogrenci sayisina gore yetersiz sayida kalmasi nedeniyle klinik oncesi egitimin eksik kaldigini dusunmektedirler. Ogrencilerin cogunlugu klinige ciktiklarinda, beceri uygulamasi konusunda kendilerini yetersiz hissettiklerini ve bu nedenle de hasta, hemsire ve diger ekip uyeleri ile sorun yasadiklarini ifade etmislerdir. Sonuc: Simulasyon ogretim yontemlerinin kullanilmasina yonelik ogrencilerin olumlu goruslerinin olmasi ve bu egitim yontemin ogrencilerin klinikte becerilerinin gelistirilmesine katkida bulunacagindan dolayi klinik ortamda kendinden emin girisimlerde bulunabilecekleri ve dolayisiyla oz guvenli hemsirelerin yetismesine katki saglayacagi dusunulmektedir.
Culture and Human Fertility

This book is divided into 2 parts. Part I deals with problems of general theory as related to human fertility. Part II presents a number of specific studies undertaken by the author and other collaborators in this investigation. These specific studies are attempts to find out the relation of cultural conditions to fertility in nonindustrial and transitional societies. This book will chiefly be of interest to individuals interested in population problems.
A description of the utilisation of the partograph by midwives in the public hospitals in the Umgungundlovu district, KwaZulu-Natal

Introduction High maternal, perinatal and under-five morbidity and mortality are some of the formidable development challenges in Africa. The World Health Organisation (WHO) estimates that worldwide, as many as 1500 women die every day due to complications related to pregnancy or childbirth (WHO 2010). The partograph or partogram, an inexpensive tool, was designed by WHO to be used by midwives for decision-making during labour. Many studies conducted in and out of Africa reflect sub-optimal use of the partograph. Aim of the study The aim of the study was to describe the utilisation of the partograph by registered midwives working in the maternity sections of public hospitals in the uMgungundlovu District in the province of KwaZulu-Natal. Methodology A quantitative descriptive cross-sectional study was used to describe the use of the partograph in the selected hospitals, and carried out in two phases. In phase one, 197 participants completed a questionnaire. In phase two, retrospective audits on 310 completed maternity records were done. The collected data was analysed using SPSS version 20 and presented in frequency tables, cross-tabulations and graphs. Results The results revealed that there were certain parameters that were given more focus when it came to correct and consistent recording, such as contractions (80.0%) and cervical dilatation (89%) whilst others were poorly done, such as the duration of labour (13.5%), pain relief (23.5%) and unrecorded partographs from the primary health care clinics and community health centres (80.8%).
Features of Polar Crystals Electrical Polarization

Unique properties of polar crystals, in particular, pyroelectricity, are described by a new representation, which expands and refines the widely used concept of spontaneous polarization. Next physical mechanism is proposed: polar crystals have a finely balanced structure highly sensitive to external influences; therefore, they are capable to generate electrical response onto non-electrical action. In other words, it is assumed that in the polar crystals no permanent polarization exists, but electrical polarization appears in them as a response to thermal, mechanical, optical, chemical and others actions. At that, the difference between pyroelectrics and piezoelectrics is not fundamental but can be explained by spatial distribution of polar-sensitive (mixed ionic-covalent) bonds, emerged as a result of compensation of atoms electronegativities. In the ferroelectrics polar-sensitive bonds can reversal their orientation with nonlinear response onto electrical field.
Circular Hough Transform Assisted CNN Based Vehicle Axle Detection and Classification

In this paper we introduce a method to detect vehicle axles in an image using CNN network which is assisted by circular Hough transform and classify vehicles based on the axle count. Previous work has failed to address the issue of detecting axles for the wide field of view. To tackle this problem, we first do multi-object detection and then further process them to detect wheels. We complement a traditional Hough-based wheel detection algorithm with CNN network to reduce the computational load and the search space, further improving the efficiency. We integrate spatial and contextual filters for systematic removal of false positive wheel detection. We used MIO data set for training our vehicle detection network. We sampled 2500 images from 20 videos to create data set for our wheel detection network. We did holdout cross validation to check vehicle and wheel detection accuracy. The pipeline is simple and robust for wheel detection in wide field of view, and computationally efficient. We test the method over 5 axle classes and got average accuracy of 89.4%.
Modeling of DC Critical Flashover of Transmission Line Insulator Long String under Windward/Leeward Side non-Uniform Pollution Condition

In areas with seasonal wind direction, transmission line insulator surface pollution layer will distribute nonuniformly between windward and leeward sides, performing like a fan shape. Previous studies found that this kind of nonuniform pollution lowers the flashover gradient of insulator. In this paper a continuous work intended for predicting de critical flashover voltage of long insulator string under windward/leeward side non-uniform pollution was presented. This research includes the establishment of a parallel resistance model considering multi-arc, a prediction of dc critical flashover voltage basing on the proposed model, and the verification through various test data from previous artificial tests. Also the corresponding discussion concerning the variation rule of surface residual pollution layer resistance, arc propagation process under different non-uniformities was made. Research results indicate that the proposed model is validated to be feasible to predict the dc flashover voltage of long string insulator with given pollution non-uniformity K and T. Under windward/leeward side non-uniform pollution, the residual pollution layer resistance decreases, causing the electrical property reduction of insulator string.
Effect of physico-chemical degradation of epoxy resin on partial discharge behavior

Epoxy resin coated electrode specimens were subjected to partial discharges (PD) in air at twice the discharge inception voltage for durations ranging to 5000 h. The PD behavior was characterized by a transition from initially large pulse type discharges (- 200 to 300 pC) to either small pulse (- 1 pC), pseudoglow, glow discharge, or a combination thereof. Although these different forms of discharges were capable of occurring simultaneously, each type tended to prevail over certain periods of the exposure time. The physical and chemical nature of the degradation products formed on the surfaces of the epoxy resin also varied accordingly, indicating that each discrete form of discharge exerts its particular effect on the overall degradation process. Droplet formation on the central portion of the epoxy surfaces typified the large pulse discharge regime, whilst crystals formed within the transition region over which small discharge pulses (- 1 pC) were usually superimposed upon a continuous glow (pseudoglow and true glow regime). The droplets were identified as being partially comprised of a mixture of acids, mainly formic, glycolic, glyoxalic and nitric acids, whilst the crystals consisted of hydrated oxalic acid. Since similar results were obtained with discharges in both air and nitrogen, the effects of gas phase reactions on the PD activity would appear to be only of secondary importance compared to the reactions taking place on the surface of the epoxy resin. Since the test cell design did not allow any pressure variation within the discharge gap, the observed discharge transition cannot be attributed to pressure changes such as may take place within occluded cavities. Nevertheless, the transition observed here is similar to what is found with actual stator bar type insulation, suggesting that pronounced chemical and physical modifications on the surface of the physical cavity inclusions in the bar insulation may account for the characteristic PD behavior observed as a function of time.
A Class of IIR Filters Synthesized Using Frequency-Response Masking Technique

This letter presents a class of infinite impulse response (IIR) filters synthesized using a system of IIR subfilters based on the frequency-response masking (FRM) technique. In the proposed class of filters, the bandedge shaping filters are a parallel connection of two allpass filters, and the masking filters are approximately linear phase IIR filters composed of a parallel connection of a delay line and an allpass filter. A design method which jointly optimizes the IIR subfilters is introduced. The proposed class of IIR filters has lower coefficient sensitivity and roundoff noise compared with conventional IIR filters.