Miracle-dz/UniFAR-FTUs huggingface dataset:
MGA-YOLO: A lightweight one-stage network for apple leaf disease detection

Apple leaf diseases seriously damage the yield and quality of apples. Current apple leaf disease diagnosis methods primarily rely on human visual inspection, which often results in low efficiency and insufficient accuracy. Many computer vision algorithms have been proposed to diagnose apple leaf diseases, but most of them are designed to run on high-performance GPUs. This potentially limits their application in the field, in which mobile devices are expected to be used to perform computer vision-based disease diagnosis on the spot. In this paper, we propose a lightweight one-stage network, called the Mobile Ghost Attention YOLO network (MGA-YOLO), which enables real-time diagnosis of apple leaf diseases on mobile devices. We also built a dataset, called the Apple Leaf Disease Object Detection dataset (ALDOD), that contains 8,838 images of healthy and infected apple leaves with complex backgrounds, collected from existing public datasets. In our proposed model, we replaced the ordinary convolution with the Ghost module to significantly reduce the number of parameters and floating point operations (FLOPs) due to cheap operations of the Ghost module. We then constructed the Mobile Inverted Residual Bottleneck Convolution and integrated the Convolutional Block Attention Module (CBAM) into the YOLO network to improve its performance on feature extraction. Finally, an extra prediction head was added to detect extra large objects. We tested our method on the ALDOD testing set. Results showed that our method outperformed other state-of-the-art methods with the highest mAP of 89.3%, the smallest model size of only 10.34 MB and the highest frames per second (FPS) of 84.1 on the GPU server. The proposed model was also tested on a mobile phone, which achieved 12.5 FPS. In addition, by applying image augmentation techniques on the dataset, mAP of our method was further improved to 94.0%. These results suggest that our model can accurately and efficiently detect apple leaf diseases and can be used for real-time detection of apple leaf diseases on mobile devices.
Preparedness for e-health in developing countries: the case of Ghana

As Ghana embarks on a national e-Health initiative there is the need to explore its preparedness in terms of socioeconomic and development, technology infrastructure and operational preparedness, and skills and human resources. This paper reports on a literature review as part of a research program, which aims to inform the development of an effective roadmap for the successful implementation of the national e-Health initiative in Ghana. The literature was searched for factors of e-Health adoption in developing countries; and realization of the anticipated benefits through IEEE, Medline, Google scholar and Google search engines. Sixteen (16) articles were reviewed were from 176 related articles that were found. The literature review found the two highest priority objectives in in e-Health Africa: providing health education for health professionals (identified in 7 of the 16 projects reported on in the literature) and improvement of primary health care services 9 of the 16 projects). Six (6) or 39% each of the 16 projects reported a lack of skills and Human Resources Socioeconomic issues, and Technology infrastructure problems reported in 22% or the remaining four (4) projects. The paper concluded that the effects of these challenges could lead to Ghana like many other developing countries struggling to adopt e-Health, its inability to realize the potential benefits of e-Health and its ability to institutionalize and sustain e-Health.
Apigenin and Baicalin, Each Alone or in Low Dose Combination, Attenuated Chloroquine Induced Male Infertility in Adult Rats

Male infertility is a worldwide health problem, which accounts for about 50% of all cases of infertility and considered as the commonest single defined cause of infertility. Recently, apigenin and baicalin exhibited a powerful antioxidant and antiapoptotic activities. Consequently, in the present study, we evaluated the possible protective effect of apigenin and baicalin, either alone or in low dose combination, on a rat model of male infertility, regarding for its effects on the hormonal assay, testicular weight, sperm parameters, oxidative-stress state, apoptosis, and histopathological changes. Twelve-week-old adult male Wister rats received 10 mg/kg/d chloroquine orally for 30 days to induce male infertility. Either apigenin (30 or 15 mg/kg/d), baicalin (100 or 50 mg/kg/d) or a combination of 15mg/kg/d apigenin and 50 mg/kg/d baicalin received daily orally 1 hour after chloroquine for 30 days, used to protect against chloroquine induced male infertility. Our result showed that both apigenin and baicalin, significantly and dose-dependently enhanced the reduced levels of serum testosterone, follicular stimulating, and luteinizing hormones, testicular weight, reduced-glutathione level, and catalase activity, sperm count, mobility and viability, and suppressed the elevated testicular malondialdehyde level and caspase-3 immunohistochemical expression, as well as they abrogated the disturbed testicular histopathological pictures, induced by chloroquine, with superiority of baicalin. Furthermore, the low dose combination therapy was as effective as the high dose apigenin therapy, except for sperm viability, where it was as powerful as the baicalin high dose. Therefore, both apigenin and baicalin either alone or in low dose combination could be promising in the management of male infertility.
Türkiye'de Bilişim Suçlarına Eğitimli İnsanların Bakışı

Bilisim teknolojilerinde meydana gelen gelismeler bircok alanda insanlarin yasam tarzini degistirmis ve buna paralel olarak ta bilisim teknolojileri ile ilgili islenen suclar ortaya cikmistir. Boylece suc ve suclu kavramlari yeni bir boyut kazanmistir. Bu calismada bilisim suclari hakkinda genel bir bilgi verilmistir. Dunyada ve Turkiye' de bilisim suclarindaki artis ele alinmistir. Daha sonra Turkiye'de egitimli insanlarin bilisim sucu ve bilisim suclari ile mucadele hakkindaki goruslerini ogrenmek icin hazirlanan bir anketin sonuclari degerlendirilmistir.
Evaluation of carotid intima media thickness and hematologic inflammatory markers in patients with chronic spontaneous urticaria

Introduction Low grade inflammation is associated with chronic spontaneous urticaria (CSU) and atherosclerosis. There are little data on the relationship between urticarial inflammation and atherosclerosis. The neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR) and mean platelet volume (MPV) have recently been studied in many diseases as a biomarker of inflammation. Aim To evaluate hematologic inflammatory parameters and subclinical atherosclerosis in CSU patients. Material and methods C-reactive protein (CRP), NLR, PLR, MPV and carotid intima media thickness (CIMT) in CSU patients were compared with healthy controls. Thirty CSU patients and 30 healthy controls participated in the study. Results Thirty CSU patients and 30 healthy controls participated in the study. 53.3% of the patient group were females, 46.7% were males and the mean age was 37.7 ±7.7. 53.3% of the healthy control group were females, 46.7% were males and the mean age was 37.1 ±7.2. Body mass index was 24.63 ±2.7 kg/m2 in the patient group and 24.83 ±2.5 kg/m2 in the control group. Left and right CIMT and CRP values were higher in CSU patients and high-density lipoproteins (HDL) values were lower in the CSU patients. There was a positive correlation between the right and left CIMT and urticaria activity severity 4 (UAS4), disease severity, and triglycerides in the patient group, also a negative correlation was found between the right and left CIMT and the HDL values. C-reactive protein was also correlated with UAS4 and disease severity. Conclusions This is the first study to evaluate subclinical atherosclerosis in CSU patients. Chronic spontaneous urticaria may be associated with an increased atherosclerotic risk. Serum CRP concentration can also be used as an objective parameter to evaluate disease severity.
Psychosocial Factors That Contribute to HIV/AIDS Risk Behaviors Among Young Black College Women

African American women are disproportionately burdened by human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS). Though African Americans represent only 12% of the population in the United States, more than 54% of HIV-positive women in the United States are of African American descent (Centers for Disease Control and Prevention [CDC], 2003). The bulk of HIV/AIDS research focuses on prevention for high-risk minority women and men who have sex with men, whereas young black college women are ignored as a risk group. Though this group may not have some of the common risk factors associated with HIV/AIDS such as poverty, injection drug use, or low levels of education, they still engage in behaviors that place them at risk for contracting HIV. This article examines risk factors that may explain young black college women's decisions to engage in unsafe sexual practices. It also provides an intellectual context for empirically based and theory-supported interventions geared toward this population. The bulk of the HIV/AIDS literature identifies all persons of African descent as African American. However, because not all persons of African lineage identify themselves as African American, the term black in this article is used in an effort to be inclusive of all individuals of African ancestry. The terms African American and black are used interchangeably throughout this article.
Early Parenteral Supplementation with Glutamine Dipeptide for Acute Myeloid Leukaemia Patients Receiving High Dose Chemotherapy

Background: Glutamine dipeptide (Gln) is one of conditionally essential amino acids that have a crucial role in cancer. Objectives: The aim of this study was to investigate the effects of early Gln supplementation in patients with acute myeloid leukemia (AML) receiving intensive chemotherapy, but without bone marrow transplant and regardless of receiving parenteral nutrition. Methods: A randomized control trial was carried out and included 46 AML patients who received high dose chemotherapy. Their ages ranged between 17-65 years. AML patients were randomly allocated as intervention group (Gln group; n=23) and control group (n=23). Gln group received intravenous supplementation with Gln (40 gm) from day 1 to day 5 of chemotherapy, while the patients in the control group received 40 gm per day of a standard amino acid mixture. Clinical end points included the body weight, body mass index, length of hospital stay, days of neutropenia, superoxide anion generation and length of neutropenic fever and serum albumin difference. White blood cells and absolute neutrophil count were done every second day till ANC reached >500μl then superoxide anion generation was measured. Results: Weight loss, length of hospital stay, the mean days of neutropenia and neutropenic fever were significantly lower in the Gln group, whereas the mean superoxide anion generation was found higher comparing to the control group (50 ng/L vs 43ng/L respectively). Complications other than febrile neutropenia were significantly less common in Gln group. Gln supplementation has resulted in significant improvement in serum total protein and serum albumin. Conclusion: This trial suggested that early Gln supplementation regardless receiving parenteral nutrition enhances neutrophil function, maintains nutritional status and decreases hospital stay.
Esporotricosis en pacientes que acuden a un centro médico de referencia, en Abancay, Perú

A descriptive study was conducted between the months of May and August 2008 in Santa Teresa Medical Center, Abancay. Of 33 patients clinically suspected with Sporotrichosis: 20 patients were identified with Sporothrix schenckii. 11 (55%) of patients were males. Children between 0 and 14 years were most affected. 60% of the lesions were fixed cutaneous being more frequent in the head and neck (40%). 55% had lessions for less than one month. In pediatric population with involvement of head and neck, Sporotrichosis should be considered in the differential diagnosis of skin lesions of patients from endemic areas.
Pupils' choices in learning with computers

An increasing proportion of education and training will require learners to make decisions about their own learning. One way in which schoolchildren can be prepared for this is by experience with computer programs which allow learner control. A term-long trial was conducted with 14–15 year old schoolchildren learning mathematics from such programs. The choices adopted by these pupils are studied and some results are reported. We introduce two measures that may allow a characterization of choices made by individual pupils.
Cell block preparation – An adjunct to fine-needle aspiration cytology – unveiled the diagnosis

Endometriosis is defined as the presence of functioning endometrium outside the uterus. Scar endometriosis is a rare entity reported in 0.03%–1.7% of women following cesarean section scars. The diagnosis is frequently made only after excision of the diseased tissue. We present a case of 28-year-old female who presented with mass on anterior abdominal wall adjacent to a previous surgical scar. Fine-needle aspiration cytology (FNAC) of the mass revealed sheets of epithelial cells, spindle-shaped cells, and hemosiderin-laden macrophages suggestive of endometriosis. Additional cell block preparation done with the aspirate material confirmed the diagnosis. The present case highlights the use of cell block preparation together with FNAC which consecutively helps in preoperative diagnosis of scar endometriosis and facilitates the best management strategy.
AT-02INTRATUMORAL DELIVERY OF THE RETROVIRAL REPLICATING VECTOR (RRV) TOCA 511 IN SUBJECTS WITH RECURRENT HIGH GRADE GLIOMA: INTERIM REPORT OF PHASE 1 STUDY (NCT 01156584)

INTRODUCTION: High grade glioma (HGG) remains resistant to standard therapies. Newer approaches, such as immunotherapy, hold great promise. Viral infection and killing of tumor cells can stimulate antitumor immune responses. A Phase 1 clinical study using an investigational retroviral replicating vector, Toca 511, injected intratumorally, in combination with investigational oral Toca FC (extended-release 5-FC) is being conducted. METHODS: The primary purpose of this study is to identify the highest safe and well tolerated dose of Toca 511 administered transcranially into recurrent HGG tumors. The starting dose was 3.9 x 10^6 Transducing Units (TU). Using a standard 3 + 3 design, doses have been escalated at half log intervals to 1.5 x 10^9 TU. 24 subjects were injected using a brain biopsy needle. Addition of gadolinium to the vector with post-operative iMRI suggested variable delivery of vector to the tumor. Subsequently 12 subjects have been treated using CED under real-time MRI-guidance. Monthly cycles of oral 5-FC are started 4 weeks after injection of the vector. RESULTS: 36 subjects across 5 vector dosing cohorts have been studied. Real-time MRI-guidance demonstrated vector delivery with confirmation of vector RNA and CD protein in tumor samples. The injection procedures and vector and 5-FC dosing have been safe and well tolerated to date. No DLTs have been observed. Tumors have been observed to regress in the area around vector infusion and some subjects have experienced improvement in clinical symptoms. A number of subjects have experienced prolonged survival with 8 of the first 17 subjects with Grade 4 tumors surviving more than 1 year. CONCLUSION: This study confirms the feasibility and safety of transcranial, intratumoral delivery of an RRV. Continued dose escalation is planned and may yield further gains in efficacy.
Modeling Complex Time Limits

In this paper we analyze complexity of time limits we can find especially in regulated processes of public administration. First we review the most popular process modeling languages. There is defined an example scenario based on the current Czech legislature which is then captured in discussed process modeling languages. Analysis shows that the contemporary process modeling languages support capturing of the time limit only partially. This causes troubles to analysts and unnecessary complexity of the models. Upon unsatisfying results of the contemporary process modeling languages we analyze the complexity of the time limits in greater detail and outline lifecycles of a time limit using the multiple dynamic generalizations pattern. As an alternative to the popular process modeling languages there is presented PSD process modeling language, which supports the defined lifecycles of a time limit natively and therefore allows keeping the models simple and easy to understand.
Long-Term Accommodation and Support for People With Higher Levels of Challenging Behaviour

Abstract The purpose of the present article is to describe the issues associated with providing lifelong accommodation and support to people with severe brain injury, neurobehavioural disability, and overt challenging behaviours. In particular, the article focuses on two groups of people within an Australian context: (a) those who live in community settings but whose behaviour is not adequately managed even by specialist outreach behaviour management services, and (b) those who are confined to aged care residential facilities and who show challenging behaviour. These groups bring to the fore different lifelong behaviour management issues. At present, if community-based clients seriously offend or have an adequate psychiatric diagnosis, they may be placed in heavily secured psychiatric units or prison. Otherwise, by default, they will reside in less restrictive options such as family homes and shared supported accommodation. We will argue that the current service system lacks the ability to apply appropriate structure and control to many clients with serious challenging behaviours, and propose that specialised facilities would make an important addition to the service system. Conversely, young clients confined to residential aged care facilities live in impoverished environments that often contribute to challenging behaviour that can be enormously disruptive, distressing, and unsafe. We will review the recent Australian State and Federal Government initiative aimed at transitioning some young people out of nursing homes, and we raise considerations for future service development. There are many individuals with the potential to make significant gains in a tightly structured setting before returning to the community, while others will manage well with long-term placement in a setting designed for residents with neurobehavioural disability. Case studies and service data are used to support these arguments, and key elements of accommodation and rehabilitation models for those in need of long-term neurobehavioural support are described.
The use of electrophysiology for the assessment of diabetic neuropathy

Whole nerve electrophysiology can provide a battery of objective, reliable and specific measures that are sensitive to the progression of diabetic symmetrical polyneuropathy (DSPN). However, under standard conditions, these measures index limited aspects of neural activity, and then only in large diameter, myelinated axons. Nerve conduction is not synonymous with "nerve function. " Electrophysiologic measures can be influenced by a variety of factors with different time courses of action and with different sensitivities to manipulation. The value of whole nerve electrophysiology must be based on a firm appreciation of the strengths and limitations of the procedure. © 1997 John Wiley & Sons, Ltd.
OLAP Solutions - Building Multidimensional Information Systems

From the Publisher: Although many commercial OLAP products are readily available -- as stand-alone tools and, increasingly, in close association with relational databases -- OLAP remains a difficult and complex technology to master. The second edition of Thomsen's classic OLAP Solutions provides a clear and comprehensive explanation of the concepts and best techniques for deploying OLAP -- no matter what tools you're using. This edition is thoroughly revised, offering expanded coverage of logical issues such as dimensional hierarchies, as well as physical issues of data storage, access, and calculation. Thomsen has also created an entirely new application section that provides a computational cross-value chain model of ten interconnected business processes within the context of a manufacturing company. The practical methods and formulas you'll learn are useful no matter what commercial OLAP tool(s) you use.
Error detection and correction in annotated corpora

Building on work showing the harmfulness of annotation errors for both the training and evaluation of natural language processing technologies, this thesis develops a method for detecting and correcting errors in corpora with linguistic annotation. The so-called variation n-gram method relies on the recurrence of identical strings with varying annotation to find erroneous mark-up. We show that the method is applicable for varying complexities of annotation. The method is most readily applied to positional annotation, such as part-of-speech annotation, but can be extended to structural annotation, both for tree structures— as with syntactic annotation—and for graph structures—as with syntactic annotation allowing discontinuous constituents, or crossing branches. Furthermore, we demonstrate that the notion of variation for detecting errors is a powerful one, by searching for grammar rules in a treebank which have the same daughters but different mothers. We also show that such errors impact the effectiveness of a grammar induction algorithm and subsequent parsing. After detecting errors in the different corpora, we turn to correcting such errors, through the use of more general classification techniques. Our results indicate that the particular classification algorithm is less important than understanding the nature of the errors and altering the classifiers to deal with these errors. With such alterations, we can automatically correct errors with 85% accuracy. By sorting the errors, we can
The Prognostic Value of Hypocholesterolemia in Sepsis

Objective:Hypocholesterolemia is a critical observation following trauma and probably contributes to inflammation during critical illness. This study has been conducted to document the cholesterol level at different time intervals in patients with sepsis and to correlate its trend with survival.Methods : Fifty-five patients from ICU meeting the criteria of sepsis were included in the study. Total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol and triglycerides were measured at the onset of sepsis (0 hour), at 24 hour and at 72 hour. The hypocholesterolemia cut off level (total cholesterol <130 mg/dL) was further correlated with survival and non survival for a period of 28 days. Results : The mean total cholesterol, HDL-C and LDL-C levels in the non surviving group were significantly less than the surviving group (p=0.000, p=0.008, p=0.04). The difference in the triglyceride level was not significant. On further analysis it was observed that the cholesterol level at the onset of sepsis (0 hour) could be used as an indicator of survival. Conclusion : The cholesterol level is altered and although the reason is not understood, it is for certain that there is a positive relationship between low serum cholesterol levels, and increased mortality. Since no data on cholesterol and lipoprotein concentrations before the septic episode are available, it was not possible to be sure whether concentrations are low because of the inflammatory response or whether the patients are susceptible to infection as a result of low lipoprotein concentrations. However, from the observations we would like to suggest that, low serum cholesterol concentrations represent a potential therapeutic target for better management of sepsis.