Miracle-dz/UniFAR-FTUs huggingface dataset:
Thermoelectric Parameter Modeling of Single-Layer Graphene Considering Carrier Concentration and Mobility With Temperature and Gate Voltage

Single-layer graphene (SLG) sheets can exhibit thermoelectric properties under the control of gate voltage. The controlled factors and regulation mechanism of SLG thermoelectric properties have become research hotspots. In this paper, a SLG thermoelectric parameter model considering carrier concentration and mobility with temperature and gate voltage is proposed. Based on the proposed model, the square resistance (<inline-formula> <tex-math notation="LaTeX">$R_{\mathrm {s}}$ </tex-math></inline-formula>) and Seebeck coefficient (<inline-formula> <tex-math notation="LaTeX">$S$ </tex-math></inline-formula>) of the SLG are calculated. The results show that the maximum value of <inline-formula> <tex-math notation="LaTeX">$R_{\mathrm {s}}$ </tex-math></inline-formula> decreases from 5.8 <inline-formula> <tex-math notation="LaTeX">$\text{K}\Omega $ </tex-math></inline-formula> to 3.2 <inline-formula> <tex-math notation="LaTeX">$\text{K}\Omega $ </tex-math></inline-formula> at the Dirac voltage when the temperature increases from 100 K to 500 K. A large and stable <inline-formula> <tex-math notation="LaTeX">$S$ </tex-math></inline-formula> can be obtained at high voltages and temperatures. The maximum value of <inline-formula> <tex-math notation="LaTeX">$S$ </tex-math></inline-formula> can reach <inline-formula> <tex-math notation="LaTeX">$161.3~\mu \text{V}$ </tex-math></inline-formula>/K at <inline-formula> <tex-math notation="LaTeX">$T = 500$ </tex-math></inline-formula> K, exhibiting a more obvious thermoelectric characteristic. Simultaneously, the saturation law of the power factor (<inline-formula> <tex-math notation="LaTeX">$Q$ </tex-math></inline-formula>) with the change of gate voltage and the amplitude regulation of <inline-formula> <tex-math notation="LaTeX">$Q$ </tex-math></inline-formula> by temperature are obtained. This work can provide a theoretical basis for analyzing the thermoelectric characteristics of SLG.
Direct Involvement of the Master Nitrogen Metabolism Regulator GlnR in Antibiotic Biosynthesis in Streptomyces*

GlnR, an OmpR-like orphan two-component system response regulator, is a master regulator of nitrogen metabolism in the genus Streptomyces. In this work, evidence that GlnR is also directly involved in the regulation of antibiotic biosynthesis is provided. In the model strain Streptomyces coelicolor M145, an in-frame deletion of glnR resulted in markedly increased actinorhodin (ACT) production but reduced undecylprodigiosin (RED) biosynthesis when exposed to R2YE culture medium. Transcriptional analysis coupled with DNA binding studies revealed that GlnR represses ACT but activates RED production directly via the pathway-specific activator genes actII-ORF4 and redZ, respectively. The precise GlnR-binding sites upstream of these two target genes were defined. In addition, the direct involvement of GlnR in antibiotic biosynthesis was further identified in Streptomyces avermitilis, which produces the important anthelmintic agent avermectin. We found that S. avermitilis GlnR (GlnRsav) could stimulate avermectin but repress oligomycin production directly through the respective pathway-specific activator genes, aveR and olmRI/RII. To the best of our knowledge, this report describes the first experimental evidence demonstrating that GlnR regulates antibiotic biosynthesis directly through pathway-specific regulators in Streptomyces. Our results suggest that GlnR-mediated regulation of antibiotic biosynthesis is likely to be universal in streptomycetes. These findings also indicate that GlnR is not only a master nitrogen regulator but also an important controller of secondary metabolism, which may help to balance nitrogen metabolism and antibiotic biosynthesis in streptomycetes.
Coordination between the circadian clock and androgen signaling is required to sustain rhythmic expression of Elovl 3 in mouse liver

X Huatao Chen (陈 华涛), Lei Gao (高 磊), Dan Yang (杨 丹), Yaoyao Xiao (肖 要要), Manhui Zhang (张 漫慧), Cuimei Li (李 翠梅), Aihua Wang (王 爱华), and Yaping Jin (靳 亚平) From the Departments of Clinical Veterinary Medicine and Preventive Veterinary Medicine, College of Veterinary Medicine, and the Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest A&F University, Yangling, 712100 Shaanxi, China
Crystal Structure and Substrate Recognition of Cellobionic Acid Phosphorylase , Which Plays a Key Role in Oxidative Cellulose Degradation by Microbes *

Young-Woo Nam (남영우), Takanori Nihira (仁平 高則), Takatoshi Arakawa (荒川 孝俊), Yuka Saito (斉藤 由華), Motomitsu Kitaoka (北岡 本光), Hiroyuki Nakai (中井 博之), and X Shinya Fushinobu (伏信 進矢) From the Department of Biotechnology, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan, Faculty of Agriculture, Niigata University, Niigata 950-2181, Japan, and National Food Research Institute, National Agriculture and Food Research Organization, Tsukuba, Ibaraki 305-8642, Japan
Expression of adipocyte biomarkers in a primary cell culture models reflects preweaning adipobiology.

Background: Obesity depends upon a balance between adipocytes associated with thermogenesis and fat storage. Results: Molecular biomarkers characterize primary adipocyte cultures from different adipose depots. Conclusions: Only adipocytes from ear mesenchymal stem cells (EMSC) failed to express the brown fat biomarkers and overall gene expression resembled that of neonatal animals. Significance: Metabolism of fat tissue in the pre-weaning period is distinct from that of the adulthood. ABSTRACT A cohort of genes was selected to characterize the adipogenic phenotype in primary cell cultures from 3 tissue sources. We compared the quantitative expression of biomarkers in culture relative to their expression in vivo, since the mere presence or absence of expression is minimally informative. Although all biomarkers analyzed have biochemical functions in adipocytes, the expression of some of the biomarkers varied enormously in culture relative to their expression in the adult fat tissues in vivo, i.e. inguinal fat (ING) for white adipocytes and brite cells, interscapular brown adipose tissue (iBAT) for brown adipocytes and ear mesenchymal stem cells for white adipocytes from adult mice. We propose that the
Comparison of Turkish and Iranian University Students’ Forgiveness, Tolerance and Happiness Levels

The aim of this study was to compare the levels of forgiveness, tolerance and happiness of university students in terms of different variables (gender, age, marital status and program) in Turkey and Iran. A total of 1234 (797 female and 437 male) university students, between 18 and 23 years old, who were studying at Hacettepe University and Ondokuz Mayıs University in Turkey and Tehran University and Tabriz University in Iran, participated in the study. They completed three data collection instruments: the Oxford Happiness Scale (OMO), Tolerance Scale (TO) and Heartland Forgiveness Scale (HFS). The analysis of the data was performed with the SPSS 23 statistical program. The results of the statistical analyses showed that the happiness and tolerance levels of university students in Turkey and Iran differ according to gender, age, marital status and educational status variables. However, when the same variables were considered, there was no significant difference in forgiveness levels. Finally, the findings were discussed in reference to previous studies.
1 Market Design , Human Behavior and Management

We review past research and forecast future directions on how the rapidly growing areas of market design and behavioral economics have influenced and will continue to impact the science and practice of management in both the private and public sectors. Using examples from various auction markets, reputation and feedback system design in online markets, matching market design in education, and the design of labor markets, we demonstrate that combining market design theory, behavioral insights, and experimental methods can lead to fruitful implementation of superior mechanisms in practice.
systematic differences between thermal and microwave hellier-type palaeointensity estimates a consequence of multidomain ias in the thermal results ?

A meta-analysis which directly compares 13 datasets of microwave and thermal Thellier palaeointensity measurements obtained from igneous rocks is reported. The results clearly indicate systematic differences in the measurements made using the two approaches: the thermal results tend to be higher (often by several tens of percent) and associated with slightly noisier Arai plots. Additionally, in nearly half of the cases considered, higher thermal palaeointensity estimates were reported to be calculated from the lowtemperature portions of concave-up Arai plots while microwave measurements made on specimens from the same core sample or rock unit were derived from more linear Arai plots. The most plausible explanation for the bulk of these differences appears to be that non-ideal behaviour caused by multidomain, vortex state, and/or interacting ferrimagnetic grains is exaggerated in the results of the thermal experiments over their microwave counterparts. A detailed investigation of the individual studies concludes that such effects may be adversely affecting some of the measurements (thermal and/or microwave) in 10 of the 13 datasets considered. It is probable that these non-ideal effects are enhanced in the thermal results over their microwave counterparts, at least in part, because of the different Thellier-type protocols that are used in the two types of study. The findings of this study suggest that biasing of absolute palaeointensity estimates by multidomain effects may be much more prevalent than previously thought and that this effect might be responsible for certain discrepancies that have been observed in the GEOMAGIA50 database. They also clearly indicate that, in addition to taking the steps they already do to avoid biasing from secondary overprints and thermally-induced alteration, future absolute palaeointensity studies of reat c any type must also take g
Phytochemical and Pharmacological Properties of Radix Codonopsis: A Review

Radix Codonopsis (RC) was a well-known Chinese traditional medicine. In clinical practice, RC was usually used to cure poor appetite, fatigue, psychoneurosis, inflammatory diseases, etc. Recently, many studies focused on its antitumor, antioxidant, anti-ulter, and antibacterial properties. This paper was a review of the phyto-chemical and pharmacological properties of RC. Moreover, the application prospect of RC was also discussed. Keywords-Radix Codonopsis (RC); Chinese Traditional Medicine; Clinical Practice; Phytochemistry; Pharmacology
Abusive supervision and workplace deviance : The moderating role of power distance Pakistan

The aim of this paper is to examine the association of abusive supervision with workplace deviance, for instance supervisory directed deviance, non-supervisory directed deviance, and emotional exhaustion. Further, in this paper we examine how power distance moderates these relationships. Cross-sectional data was collected through selfadministrated questionnaire from banking sectors in Lahore, Pakistan. To test the hypothesis, structural equation-modeling (SEM) technique is used; moreover, for moderation test hierarchical regression is applied. The finding suggests that abusive supervision is positively associated with supervisory directed deviance, non-supervisory directed deviance, and emotional exhaustion. In moderation test, the individual power distance influences the relationships between abusive supervision and supervisory directed deviance as well as emotional exhaustion. However, it has not affected the relationship among abusive supervision and non-supervisory directed deviance. The results indicate that mostly mistreated employees involved in negative reactions and these reactions are not only contained deviating behavior, it also influences them emotionally. By addressing abusive supervision issues, this research has key implication for abusive supervision practically. In practical terms, „Policy makers‟ can also take benefit from this research by considering how abusive supervision can influence the employees‟ wellbeing in organizations while making organizational polices.
Likelihood-free MCMC with Amortized Approximate Likelihood Ratios

Posterior inference with an intractable likelihood is becoming an increasingly common task in scientific domains which rely on sophisticated computer simulations. Typically, these mechanistic models do not admit tractable densities forcing practitioners to rely on approximations during inference. This work proposes a novel approach to address the intractability of the likelihood and the marginal model. We achieve this by learning a flexible estimator which approximates the likelihood-to-evidence ratio. The resulting amortized ratio estimator is embedded in MCMC samplers such as Metropolis-Hastings and Hamiltonian Monte Carlo to approximate the likelihood-ratio between consecutive states in the Markov chain, allowing us to draw samples from the intractable posterior. Techniques are presented to improve the numerical stability. We demonstrate our approach on a variety of benchmarks and compare against well-established approximate inference techniques. Scientific applications in high energy and astrophysics with high-dimensional observations show its applicability.
Motivating Students in Collaborative Activities With Game-Theoretic Group Recommendations

Recommending educational resources to groups of students is a common task in collaborative learning contexts. However, differences in within-group motivational factors might lead to conflicts in students’ intention to use the resources. Previous methods fail to achieve high goodness of recommendation for the majority of students in heterogeneous groups. This study demonstrates a game-theoretic solution for recommending educational resources to homogeneous and heterogeneous groups. The group members are the players, the resources comprise the set of possible actions, and selecting those items that will maximize all students’ motivation in the collaborative activity is a problem of finding the Nash Equilibrium (NE). In case the NE is Pareto efficient, none of the players can get more payoff (motivation) without decreasing the payoff of any other player, indicating an optimal benefit for the group as a whole. The suggested approach was empirically evaluated in a controlled experiment with a real dataset. The relevance of each delivered item to its corresponding students was explored both from the perspective of the group and its the individual students. The accuracy of the predicted group/individual motivation, the goodness of the ranked list of recommendations, and the problem-solving performance for the treatment group were significantly higher compared to the control groups. Limitations of the approach, as well as future work plans conclude the paper.
The Relationship between Ethical Work Climate and Organizational Innovation

In the era of globalization today, ethics have become a concern in researching due to the level of growth in innovation. This study has examined the level of ethical work climate and the level of organizational innovation among researchers (academic staff) at University XYZ. Furthermore, this study has determined the relationship between ethical work climate and organizational innovation. This study has applied a quantitative approach to collect data using a survey questionnaire and analyzed through SPSS to find results. This study has distributed 470 questionnaires among the academic researchers in all faculties at University XYZ. Based on the results, it has found that researcher (academic staff) at University XYZ has a sound ethical work climate practices while conducting research. Meanwhile, respondent's implementation towards innovation while doing their research is moderate. Besides, the study has noted a positive correlation and significant relationship between ethical work climate and organizational innovativeness among researcher (academic staff). It indicates that a positive ethical work climate leads to putting positive influences on organizational innovativeness.
Is Good Governance Priced?

A new governance index is constructed, which forms the basis of a new governance valuation factor, defined as the product of the firm governance index and the country institutional quality. Using monthly returns of 4,714 blue chip firms from 35 OECD equity markets for 17 years, our tests of variants of the augmented-CAPM, show that a two factor CAPM augmented with a factor mimicking portfolio based on our new governance metric yields the highest explanatory power in multi-country samples. In general, our results indicate variations in abnormal returns on portfolios that reflect returns differences between democratic (strong) and dictatorship (weak) governance sorted deciles not explained by existing augmented CAPMs. This confirms the importance of differences in governance and that minority investors should seek a premium to compensate for potential welfare losses and a means of hedging these losses within a conventional asset pricing framework. We argue that this is representative of the revealed preferences of insider controlling groups within firms towards expropriating minority outsiders
Towards a Generally Accepted Validation Methodology for Sensor Models-Challenges , Metrics , and First Results

In order to significantly reduce the testing effort of autonomous vehicles, simulation-based testing in combination with a scenario-based approach is a major part of the overall test concept. But, for sophisticated simulations, all applied models have to be validated beforehand, which is the focus of this paper. The presented validation methodology for sensor system simulation is based on a state-of-the-art analysis and the derived necessary improvements. The lack of experience in formulating requirements and providing adequate metrics for their usage in sensor model validation, in contrast to e.g. vehicle dynamics simulation, is addressed. Additionally, the importance of valid measurement and reference data is pointed out and especially the challenges of repeatability and reproducibility of trajectories and measurements of perception sensors in dynamic multi-object scenarios are shown. The process to find relevant scenarios and the resulting parameter space to be examined is described. At the example of lidar point clouds, the derivation of metrics with respect to the requirements is explained and exemplary evaluation results are summarized. Based on this, extensions to the state-of-the-art model validation method are provided.
HLA-DRB allels , IL-10 and Vitamin D level : Potential Impact on Multiple Sclerosis

Background Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease with unknown etiology. Variation in the HLA-DRB1 gene is the potent genetic risk factor for promoting MS. Other agents relate with an increased risk of developing MS include the cytokines levels such as interleukin-10 (IL10) and the vitamin D (vit. D) deficiency. Objectives To study a possible role of HLA-DRB1, vit. D deficiency as a risk factor for MS development and to estimate the level of IL-10 in the serum of MS patients and its role in disease initiation or progression. Methods Sixty MS patients, of them 30 were newly diagnosed with an age range between 13 and 58 years were included in this study, in addition to thirty healthy volunteers their gender and age matched with patients group serve as a control group. Blood samples collected to assess serum levels of vit. D and IL-10 by Enzyme-Linked Immunosorbant Assay (ELISA) and for DNA extraction, which used in the HLA-DRB1 2 digit genotyping. Results The HLA-DRB1 genotyping revealed that the HLA-DRB1*15 frequency was higher but statistically insignificant in the MS patients as compared with healthy control group. IL-10 level was significantly lower in MS patients on treatment than the control group. On the other hand, vit. D in the newly diagnosed MS patients was significantly different from the control group (higher in the control group), but there was no variance with MS patients on treatment, the level of vit. D in the studied groups was less than global value. Conclusion In MS patients the frequency of HLA-DRB1*15 was higher than control group but the difference was not significant. In addition, the level of IL-10 and vit. D may have a role in the development of MS.
Tiotropium administered by a pressurized metered dose inhaler ( pMDI ) and spacer produces a similar bronchodilator response as that administered by a Rotahaler s in adult subjects with stable moderate-to-severe COPD

ont matter & 2007 2007.07. 006 thor. Tel. : +91 20 brashier@crfindia Summary Background: Tiotropium is a new long-acting anticholinergic bronchodilator, which is recommended as first-line therapy in the management of chronic obstructive pulmonary disease (COPD). It is currently available in the form of a dry powder inhaler worldwide. Some COPD patients find it difficult to generate inspiratory flow rates of up to 40 l/min, which is required for the drug to reach the airways. To overcome this, a new pMDI form has been developed for administration of tiotropium in patients with COPD. The clinical efficacy of this mode of tiotropium delivery has, so far, not been compared with the currently available dry powder inhaler (DPI) devices. Aims and objectives: To compare the bronchodilator effects of a single dose of 18mcg of tiotropium administered via a pressurized meter dose inhaler (pMDI) and spacer with the currently available DPI form through Rotahaler. Study design: A randomized, double-blind, double-dummy, three-period, placebocontrolled, crossover, single-center study was conducted in 19 patients with stable COPD. Single doses of tiotropium (18mcg) or placebo were administered on three separate study days (4–7 days apart) through a Rotahaler and pMDI with a non-static spacer (Zerostat, Cipla Ltd.). During each study visit forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) were measured over a period of 24 h at 11 different time points (0, 15, 30min, 1, 2, 3, 4, 6, 8, 12 and 24 h), using a bellows spirometer (Vitalograph 2160, UK) while static parameters like inspiratory capacity (IC), residual volume (RV), intrathoracic
Depression in the House : The Effects of Household Air Pollution from Solid Fuel Use in China

While adverse health effects of ambient air pollution have been well documented, there is scarce evidence on the impact of household air pollution (HAP) on mental health. We investigated the causal link between HAP exposure from the use of solid fuel on depressive symptoms using a nationally representative dataset of middle-aged and older population in China. Employing the propensity match score method (PSM), matching and adjusting for potential confounders, we found significantly higher Center for Epidemiological Studies Depression Scale (CES-D) score and risk of depressive symptoms among solid fuel users than clean fuel users. These associations were especially stronger for older females who were less educated, of lower income, of higher body mass index, or had chronic diseases.
Fluorescence Lifetime Imaging Endoscopy

We present two FLIM endoscopes for clinical imaging and in vivo cell biology. For subcellular confocal imaging we demonstrated the first confocal FLIM endomicroscope, implementing TCSPC with a CellvizioGI, which we have now developed as a self-contained wheeled instrument (1.0 x 0.7 m) incorporating a tunable excitation laser and acquiring images in < 10 s. This has been applied to image FRET in live cells and to image tissue autofluorescence, for which we are implementing “FIFO” for image montaging. For diagnostic screening/guided biopsy, we have developed a complementary wide-field FLIM endoscope employing time-gated detection with violet and UV excitation for imaging over mm-cm fields of view.