Miracle-dz/UniFAR-FTUs huggingface dataset:
Platelet-Activating Factor-Acetylhydrolase Gene (PLA2G7) Expression inChildren with a History of Food Anaphylaxis

Background: One of key functions in the pathogenesis of anaphylaxis is held by platelet-activating factor (PAF). However, no research on detection of transcriptional activity of PAF-acetylhydrolase gene (PLA2G7) in patients with anaphylaxis has been held so far. The aim of this study is to evaluate transcriptional activity (expression at mRNA level) of PLA2G7 gene (plateletactivating factor acetylhydrolase) in patients with a history of anaphylaxis. Methods: 97 children were enrolled in the study: 27 children with a history of food anaphylaxis (group 1); 35 children with atopic dermatitis (group 2); 35 children without allergic diseases (group 3). Group 3 children were tested with Phadiatop and Phadiatop Infant (“Phadia 100”; “Phadia AB”, Sweden): 26 children were IgE-negative, 9 children were IgE-positive. RNA was extracted from blood samples with Trizol RNA Prep kits (“Isogen”, Russia). cDNA production was performed with MMLV RT kit (“Evrogen”, Russia). Real-time PCR was held with CFX-96 device (“Bio-Rad”, USA) and qPCRmix-HS PCR mix (“Evrogen”, Russia). Oligonucleotide primers and probes were synthesized at “DNKSintez” (Russia). Results: In children with a history of food anaphylaxis statistically significant decrease in PLA2G7 gene expression was detected (p<0.05) in compare with children free of allergic diseases. Transcriptional activity of PLA2G7 was significantly lower in children with severe anaphylaxis and in children with moderate anaphylaxis in compare with mild anaphylaxis children (p<0.05). In moderate/severe anaphylaxis children PLA2G7 expression was more than three times decreased in compare with atopic dermatitis children (p<0.05). In children with anaphylaxis characterized by clinical symptoms of cardiovascular manifestations the PLA2G7 expression level was significantly reduced in compare with anaphylaxis children free of cardiovascular symptoms (p<0.05). Conclusion: Reduction of blood cells PLA2G7 mRNA level in children with a history of food anaphylaxis may be considered to be a biomarker of severe anaphylaxis.
Seismic interpretation of sill complexes in sedimentary basins: implications for the sub-sill imaging problem

Application of 3D seismic reflection data to igneous systems in sedimentary basins has led to a revolution in the understanding of mafic sill complexes. However, there is considerable uncertainty on how geometries and architecture of sill complexes within the subsurface actually relates to geometries in seismic reflection data. To provide constraints on how sill complexes in seismic data should be interpreted, we present synthetic seismograms generated from a seismic-scale (22 × 0.25 km) outcrop in East Greenland constrained by abundant field data. This study highlights how overlying igneous rocks adversely affect imaging of underlying intrusions and rocks by decreasing seismic amplitude, frequency and making steeply dipping features near-impossible to image. Furthermore, seismic modelling in this study shows that, because of the high impedance contrast between siliciclastic host rock and dolerites, very thin (1–5 m) intrusions should in principle be imaged in reflection seismic data at 3 km depth. However, comparison with actual seismic data with well data shows significant amounts of unimaged sill intrusions, and this is likely due to limited seismic resolution, overburden complexity, inadequate velocity-models, and interference between reflections from closely spaced sills and sill splays. Significant improvements to sill imaging and interpretation could be made by better predicting occurrence and geometry of sill intrusions and including these in velocity models. Supplementary material: A scaled version of the input panel (Fig. 5d) used for seismic modelling (A1), and very high resolution versions of subfigures in Figure 11 (A2–3) are available at https://doi.org/10.6084/m9.figshare. 5607160
Polarimetric survey of main-belt asteroids , III. Results for 33 X-type objects

Aims. We present results of a polarimetric survey of main-belt asteroids at Complejo Astronomico El Leoncito (Casleo), San Juan, Argentina. The aims of this survey are to increase the database of asteroid polarimetry, to estimate diversity in polarimetric properties of asteroids that belong to different taxonomic classes, and to search for objects that exhibit anomalous polarimetric properties. Methods. The data were obtained with the Torino and CASPROF polarimeters at the 2.15 m telescope. The Torino polarimeter is an instrument that allows the simultaneous measurement of polarization in five different bands, and the CASPROF polarimeter is a two-hole aperture polarimeter with rapid modulation. Results. The survey began in 2003, and up to 2009 data of a sample of more than 170 asteroids were obtained. In this paper the results for 33 X-type objects are presented, several of them are being polarimetrically observed for the first time. Using these data we found polarization curves and polarimetric parameters for different groups among this taxonomic class and that there are objects with very different albedo in the sub-classes of the X taxonomic complex.
Allelopathy and Potential Impact of Invasive Acacia saligna (Labill.) Wendl. on Plant Diversity in the Nile Delta Coast of Egypt

The introduction of Acacia saligna in the north Nile Delta of Egypt is causing harmful impacts on the plant diversity. Thirty stands were established in both invaded and non-invaded areas. The species abundance and diversity were determined. Soil samples were collected and analyzed. The correlation between vegetation and soil variables was investigated. The allelopathic potential of water and methanolic extracts from A. saligna leaves and flowers were examined. Approximately 19 and 50 plant species were recorded in the invaded and non-invaded areas, respectively. Aegilopus bicornis was the dominant species in the invaded areas, while Senecio glaucus dominated the non-invaded areas. The non-invaded areas attained high values of species richness and lower values of evenness than invaded one. Soil analysis revealed that the non-invaded areas attained significantly high content of sulphate, bicarbonate, Na, K and Ca than invaded areas. The methanolic and aqueous extracts of the flowers attained IC50 values of 2.89 g/L and 33.89 g/L, respectively on the germination of Hordeum murinum. However, IC50 values for leaves were 6.08 g/L and 55.04 g/L, respectively. The methanolic extracts of A. saligna expressed more effect on seedling length than the aqueous extracts. The aqueous extract showed stimulatory effect at low concentrations. The invasive successes of A. saligna seem to be related to its ability to release allelopathic compounds together with its competition for resources such as nutrient, water and sunlight. These findings may also have useful implications for coastal ecosystem management and conservation
The asymmetric geospace as displayed during the geomagnetic storm on 17 August 2001

Abstract. Previous studies have shown that conjugate auroral features are displaced in the two hemispheres when the interplanetary magnetic field (IMF) has a transverse (Y) component. It has also been shown that a BY component is induced in the closed magnetosphere due to the asymmetric loading of magnetic flux in the lobes following asymmetric dayside reconnection when the IMF has a Y component. The magnetic field lines with azimuthally displaced footpoints map into a “banana”-shaped convection cell in one hemisphere and an “orange”-shaped cell in the other. Due to the Parker spiral our system is most often exposed to a BY-dominated IMF. The dipole tilt angle, varying between ±34∘, leads to warping of the plasma sheet and oppositely directed BY components in dawn and dusk in the closed magnetosphere. As a result of the Parker spiral and dipole tilt, geospace is asymmetric most of the time. The magnetic storm on 17 August 2001 offers a unique opportunity to study the dynamics of the asymmetric geospace. IMF BY was 20–30 nT and tilt angle was 23∘. Auroral imaging revealed conjugate features displaced by 3–4 h magnetic local time. The latitudinal width of the dawnside aurora was quite different (up to 6∘) in the two hemispheres. The auroral observations together with convection patterns derived entirely from measurements indicate dayside, lobe and tail reconnection in the north, but most likely only dayside and tail reconnection in the Southern Hemisphere. Increased tail reconnection during the substorm expansion phase reduces the asymmetry.
PRINCIPAL’S INTERPERSONAL COMMUNICATION BASED ON JAVANESE CULTURAL VALUES (MULTISITE STUDY ON THE CHILD FRIENDLY SCHOOLS IN SURAKARTA)

The study aims to describe interpersonal communication based on Javanese cultural values. Based on the characteristics of subject and research focus, the study used a qualitative approach. The data collection employed an in-depth interview, observation, and documentation. The data are analysed using interactive technique. The data are validated using triangulation, member check and peer discussion technique. The results of the study can be stated as follows. The principals’ communication could use Javanese cultural values fluently so that they could be useful for: a) developing high effectiveness of organizational communication, b) overcoming a personal problem of information, c) solving an interpersonal communication problem, d) solving an organizational problem, e) overcoming a problem of language and understanding, f) solving any conflict, g) increasing a subordinate communication, h) coordinating and holding any meeting well, building a solid team, j) promoting innovation, k) motivating subordinates, and l) making any negotiation
More empirical evidence on the adoption of chick peas in Western Australia. or: Different ways of thinking about nothing.

This paper presents various econometric models of the adoption of chick peas in Western Australia. Data are available on both whether farmers intend to adopt, and the intensity of adoption, defined by the area planted. Traditionally, analysis of such data has focussed on the probability of adoption (using Probit/Logit models), or assumed that intensity and adoption are determined by a single process (Tobit models). However, an alternative specification, which is not commonly used in adoption studies, is to allow for two processes, one determining adoption, the second intensity, and estimate these jointly (i.e. Double Hurdle models). The implications of using these alternative specifications for inferences about the causes of adoption are explored.
Lithium and rotation in F and G dwarfs and subgiants

Lithium abundances have been determined in 127 F and G Pop I stars based on new measurements of the equivalent width of the6707 A Li I line from their high resolution CCD spectra. Distances and absolute magnitudes of these stars have been obtained from the Hipparcos Catalogue and their masses and ages derived, enabling us to investigate the behaviour of lithium as a function of these parameters. Based on their location on the HR diagram superposed on theoretical evolutionary tracks, the sample of the stars has been chosen to ensure that they have more or less completed their Li depletion on the main sequence. A large spread in the Li abundances is found at any given eective temperature especially in the already spun down late F and early G stars. This spread persists even if the "Li-dip" stars that have evolved from the main sequence temperature interval 6500 6800 K are excluded. Stars in the mass range up to 2 M=M when divided into three metallicity groups show a linear correlation between Li abundance and mass, albeit with a large dispersion around it which is not fully accounted for by age either. The large depletions and the observed spread in Li are in contrast to the predictions of the standard stellar model calculations and suggest that they are aided by non-standard processes depending upon variables besides mass, age and metallicity. The present study was undertaken to examine, in particular, the eects of rotation on the depletion of Li. No one-to-one correlation is found between the Li abundance and the present projected rotational velocity. Instead the observed abundances seem to be dictated by the rotational history of the star. However, it is noted that even this interpretation is subject to the inherent limitation in the measurement of the observed Li EQW for large rotational velocities.
Clinical Characteristics of Patients Diagnosed with Delta Granule Platelet Storage Pool Deficiency (Δ-PSPD) at the Detroit Medical Center (DMC), Detroit MI

Platelets are cells that are essential for maintaining hemostasis. They contain numerous substances that mediate both clotting and thrombolysis. These substances are stored principally in two types of organelles, alpha and delta (dense) granules (20). Storage pool deficiency (SPD) is a heterogeneous bleeding disorder related to a decreased number of these specific platelet organelles resulting in platelet dysfunction. Patients having SPD often present with a history of easy bruising, frequent epistaxis, and at times with positive family history (21).
Uncertainties of Estimates of Inertia–Gravity Energy in the Atmosphere. Part II: Large-Scale Equatorial Waves

Abstract This paper analyzes the spectra and spatiotemporal features of the large-scale inertia-gravity (IG) circulations in four analysis systems in the tropics. Of special interest is the Kelvin wave (KW), which represents between 7% and 25% of the total IG wave (zonal wavenumber k ≠ 0) energy. The mixed Rossby–gravity (MRG) mode comprises between 4% and 15% of the IG wave energy. At the longest scales, the KW spectra are fitted by a law while the MRG energy spectrum appears flat. At shorter scales both modes follow a −3 law. Energy spectra of the total IG wave motion at long zonal scales (zonal wavenumber smaller than 7) have slopes close to −1. The average circulation associated with KW is characterized by reverse flows in the upper and lower troposphere consistent with the ideas behind simple tropical models. The inverse projection is used to quantify the role of Kelvin and MRG waves in current analysis systems in the upper troposphere over the Indian Ocean. At these levels, easterlies between 10°S a.
Does Internationalization Pay Off? A Study of the Perceived Benefits and Financial Performance of the International Operations of Brazilian Companies

Compensa la internacionalizacion? Un estudio sobre las ventajas percibidas y el rendimiento financiero de operaciones internacionales de empresas brasilenasA internacionalizacao compensa? Um estudo dos beneficios percebidos e desempenho financeiro das operacoes internacionais das companhias brasileiras
Liquidity Providers on the Nordic Exchange

_____________________________________________________________________________________ Abstract The purpose of this paper is threefold. Firstly, the paper examines the relationship between stock returns and market makers on the Nordic Exchange. As the first study of its kind this paper focuses on the introduction of a market making service, but also the termination of such a service and its effects on asset pricing. The findings are in line with previous studies that the introduction of a liquidity provider is associated with abnormal returns. The results also show that there is no statistically significant evidence that the removal of a liquidity provider affects stock returns. Secondly, we analyze the effects on market quality and trading activity following the removal of a liquidity provider. We find no significant results that would indicate that the firms terminating their liquidity provider agreement suffer from a worsened market quality such as increased spreads, decreased market depth or trading activity. Finally, as the first paper to study which firms choose to terminate their contract with a liquidity provider, we perform a probit regression on common firm characteristics. We find evidence that the attributes turnover and spread are the foremost determinants in the firms’ decision to terminate its liquidity providing contract.
Relative submajorization and its use in quantum resource theories

We introduce and study a generalization of majorization called relative submajorization and show that it has many applications to the resource theories of thermodynamics, bipartite entanglement, and quantum coherence. In particular, we show that relative submajorization characterizes both the probability and approximation error that can be obtained when transforming one resource to another, also when assisted by additional standard resources such as useful work or maximally-entangled states. These characterizations have a geometric formulation as the ratios or differences, respectively, between the Lorenz curves associated with the input and output resources. We also find several interesting bounds on the reversibility of a given transformation in terms of the properties of the forward transformation. The main technical tool used to establish these results is linear programming duality.
Statistical analysis of time-dependent earthquake occurrence and its impact on hazard in the low seismicity region Lower Rhine Embayment

SUMMARY The time-dependence of earthquake occurrence is mostly ignored in standard seismic hazard assessment even though earthquake clustering is well known. In this work, we attempt to quantify the impact of more realistic dynamics on the seismic hazard estimations. We include the time and space dependences between earthquakes into the hazard analysis via Monte Carlo simulations. Our target region is the Lower Rhine Embayment, a low seismicity area in Germany. Including aftershock sequences by using the epidemic type aftershock-sequence (ETAS) model, we find that on average the hypothesis of uncorrelated random earthquake activity underestimates the hazard by 5‐10 per cent. Furthermore, we show that aftershock activity of past large earthquakes can locally increase the hazard even centuries later. We also analyse the impact of the so-called long-term behaviour, assuming a quasi-periodic occurrence of main events on a major fault in that region. We found that a significant impact on hazard is only expected for the special case of a very regular recurrence of the main shocks.
Grampian migmatites in the Buchan Block, NE Scotland

Rocks exposed along the Scottish coast between Fraserburgh and Inzie Head contain information critical to understanding the evolution of the Buchan Block, the type locality for low‐P, high‐T regional metamorphism, and its relationship with the rest of the Grampian terrane, one of the major tectonostratigraphic components of the Scottish Caledonides. The ~8 km long section traverses a regional network of shear zones and, at the highest grades around Inzie Head, passes into the core of the Buchan Anticline, a large‐scale open fold that is commonly regarded as a late structure, post‐dating metamorphism. The metasedimentary rocks increase in grade from upper amphibolite to granulite facies and preserve unequivocal evidence for partial melting. The diatexite migmatites around Inzie Head, along with other gneissose units within the Buchan Block, have been regarded as allochthonous Precambrian basement rocks that were thrust into their current position during the Grampian orogenesis. However, field observations show that the onset of in situ partial melting in metapelitic rocks, which was associated with the formation of garnet‐bearing aplites and associated pegmatites, occurred around Fraserburgh, where shear fabrics are absent. Thus, the rocks preserve a continuous metamorphic field gradient that straddles the shear zone network. This observation supports an alternative interpretation that anatexis was the result of mid‐Ordovician (Grampian) metamorphism, rather than an older tectonothermal event, and that the Inzie Head gneisses are autochthonous. Using an average mid‐Dalradian pelite as a plausible representative protolith, phase equilibria modelling satisfactorily reproduces the observed appearance and disappearance of key minerals providing that peritectic garnet produced with the first formed melts (represented by the garnet‐bearing aplites) depleted the source rocks in Mn. The modelled metamorphic field gradient records a temperature increase of at least 150 °C (from ~650 °C near Fraserburgh to in excess of 800 °C at Inzie Head) but is isobaric at pressures of 2.7–2.8 kbar, suggesting the Buchan Anticline developed synchronous with partial melting. The Buchan Anticline is likely an expression of crustal thinning and asthenospheric upwelling, which produced voluminous gabbroic intrusions that supplied the heat for Buchan metamorphism.
Water and nitrogen effects on growth and allocation patterns of creosotebush in the northern Chihuahuan Desert.

A field experiment udng 2 patterns of irrigation and 1 level of nitrogen fertilizer (10 g-N m-2) was conducted in order to discern water and nitrogen interactions that may control production of creosotebush, (Laweu tridentatu (D.C.) Cov. The 2 patterns of irrigation simulated precipitation from small, frequent events (6 mm water added weekly) or large, infrequent events (25 mm water added monthly). Understanding the factors controlling the production of this rangeland shrub may aid in the development of strategies for its management. Vegetative growth occurred mostly during March-May (spring)
A SOLUTION FOR TRANSPORTATION PLANNING IN SUPPLY CHAIN

An advanced optimization system for Vehicle Routing and Scheduling Problems (VRSP), which is one of the Supply Chain Planning modules, is introduced. An object oriented system, Computer Aided Routing and Scheduling (CARS) can handle complicated distribution models using advanced heuristic optimization algorithms. To classify various types of routing and scheduling problems in a structured manner, a classi cation scheme is introduced based on the main objects of VRSP. Also, the modeling and solution approach in the CARS optimization engine has been elaborated. Main static and dynamic objects of the system as well as their relationships and interactions have been explained. The user interface in addition to the planning and operational features of the system is described in detail.
Length sensing and control for Einstein Telescope Low Frequency

In this paper we describe a feasible length sensing and control scheme for the low frequency interferometers of the Einstein Telescope (ET-LF) along with the techniques used to optimise several optical parameters, including the length of the recycling cavities and the modulation frequencies, using two numerical interferometer simulation packages: Optickle and Finesse. The investigations have suggested the use of certain combinations of sidebands to obtain independent information about the different degrees of freedom.