Miracle-dz/UniFAR-FTUs huggingface dataset:
Sustainable tourism and the management of nearshore coastal places: place attachment and disruption to surf-spots

ABSTRACT Surfing, a dominant recreational activity in many coastal areas, is a primary driver of local and international tourism. Surf-spots, nearshore oceanic locations where waves break and surfing occurs, are essential community resources. Yet, many surf-spots are at risk of degradation from climate change and other factors. Knowing whether and why surfers consider surf-spots as meaningful places can inform sustainable management of these resources, benefitting the environment and users alike. This study examines place attachment and disruption in relation to surf-spots through an online survey of 1055 surfers in California, where surfing is an important recreational and touristic industry. Our findings suggest that surfers exhibit high fidelity to specific surf-spots and develop deep attachments to those spots, with the strength of the attachment varying depending on the type of surf-spot. Some respondents consider surf-spots to be “part of their family”; few respondents describe no attachments. We conclude that, despite being dynamic oceanic locations, surf-spots are meaningful places for surfers. This importance, combined with the value of surf-spots as resources driving coastal tourism and recreation, warrants systematic consideration of surf-spots as natural resources by managers, and suggests that user–place attachment should be better understood at surf-spots and other tourism sites.
Discretely Tunable Optical Frequency Synthesizer Utilizing a Femtosecond Fiber Laser Injection-Locking Technique

In this letter, we propose a discretely tunable optical frequency synthesizer (DTOFS) based on distributed-feedback (DFB) lasers that can be selectively injection locked to a desired single mode of the femtosecond fiber laser comb. The methods for the injection locking, the monitoring of the lock status, and the selection of the desired comb mode are given. We demonstrate the discrete tunability of the DTOFS by constructing two frequency-stabilized DFB lasers, both of which are injection locked to a respective single mode of the fiber laser comb with the frequency difference, which is an exact multiple of the comb repetition frequency.
Religious urban decolonization: new mosques/antique cities

ABSTRACT This article explores the changing nature of urban landscapes and everyday life in the context of indigenous religion within settler-colonial societies. We argue that against the rationalization of modern cities in which marginalized and minority groups are generally muted, religion, particularly within settler-colonial societies, increasingly becomes a way of claiming the city. Our empirical case study is the reconstruction, inauguration, and daily use of the Lababidi mosque in the ethnically mixed city of Acre (northern Israel). By analysing the renovation process, we focus on the unique strategies by which the Muslim community challenges the hegemonic logic of modern city planning. We show that urban spaces and landscapes in Acre are becoming increasingly influenced by the religious claims and religious buildings of indigenous communities, to challenge the prevailing colonizers’ urban planning and logic. Our case study shows that the struggle over religious sites is fought on all urban fronts and influences a variety of issues within the multi-cultural multi-ethnic city. This struggle does not end with the simple demand for more democratic urban procedures, but is also a mechanism that marginalized urban citizens can use to challenge the prevailing colonial-settler logic and its domination of the urban landscape.
Followup in Psychoanalysis: Clinical and Research Values

Psychoanalysis has never developed a tradition of systematic followup study to evaluate outcome and to improve technique and theory for a variety of reasons, partly theoretical, stemming from the conception of the unfolding transference neurosis and its analytic resolution as the precondition for cure, and partly historical, having to do with the happenstance of its development as a private practice–based discipline and training outside of the academic setting. Freud, however, was never bound by such strictures and published whatever post–treatment data he acquired on all his best–known case histories. But following Freud most analysts, with some notable exceptions, eschewed followup activity as unanalytic. It is this tradition that more recent studies like those of Pfeffer in New York and the Psychotherapy Research Project of The Menninger Foundation in Topeka have squarely challenged. Data are presented from the Menninger project dealing specifically with the impact of routine planned followup on issues of treatment termination and resolution and on the nature of the post–treatment period. The degree and kind of patient cooperation with the followup inquiry, the impact of followup on treatment termination and resolution (both impeding and facilitating), and the role of followup intervention in relation to return to formal post–treatment therapy (or consolidating against it), are all discussed.
Competition Efficiency Analysis of Croatian Junior Wrestlers in European Championship

Croatian junior wrestler won a bronze medal at the European Championship 2016 year. Considering the potential of our wrestlers there is an obvious need of technical and tactical analysis so our juniors and seniors U23 wrestlers would be able to achieve even better results. Match analysis were conducted by LongoMatch 0.20. 1. Seven matches of Croatian wrestlers were analysed. Time parameters, score efficiency, technical efficiency and tactical structure were observed and analysed from the aspect of attack and defence phase and successful/unsuccessful techniques. This paper shows descriptive parameters and competitor efficiency were calculated. The results show a great number of positive score in a standing position in relation to parterre position. The parameters of competitive efficiency (0.49 points per minute) show better attacking efficiency (1.32 points per minute) in relation to defence efficiency (0.83 points per minute). Croatian wrestlers achieve less score per minute in relation with elite wrestlers, but it is visible a significant progress in technical and tactical efficiency in relation in the past three year. According to place realization of technique, Croatian wrestlers realized more technique in the center, while opponents realized technique in the zone and moving to the zone. Further analysis of efficiency and individualisation training will improve efficiency of Croatian national wrestlers.
A randomized clinical trial comparing open and arthroscopic stabilization for recurrent traumatic anterior shoulder instability: two-year follow-up with disease-specific quality-of-life outcomes.

BACKGROUND The literature comparing open and arthroscopic repair for glenohumeral instability is conflicting. We performed a prospective, expertise-based, randomized clinical trial to compare open shoulder stabilization with arthroscopic shoulder stabilization by measuring quality-of-life outcomes and recurrence rates at two years among patients treated for traumatic anterior shoulder instability. METHODS Computer-generated, variable-block-size, concealed randomization allocated 196 patients to either the open-repair group (n = 98) or the arthroscopic-repair group (n = 98). An expertise-based randomization design was employed to avoid a differential bias in terms of physician experience. Outcomes were measured at baseline, at three and six months postoperatively, and at one and two years postoperatively with use of the Western Ontario Shoulder Instability Index (WOSI) and the American Shoulder and Elbow Surgeons (ASES) functional outcome scale. Recurrent instability was also analyzed. RESULTS There were no significant differences in outcome scores at baseline. At two years, seventy-nine patients in the open group and eighty-three patients in the arthroscopic group were available for follow-up. There was no significant difference in mean WOSI scores between the groups; the mean WOSI score (and standard deviation) for the open group was 85.2 ± 20.4 (95% confidence interval [CI] = 80.5 to 89.8), and for the arthroscopic group, 81.9 ± 19.8 (95% CI = 77.4 to 86.4); p = 0.31. There was also no significant difference in mean ASES scores: 91.4 ± 12.7 (95% CI = 88.5 to 94.4) for the open group and 88.2 ± 15.9 (95% CI = 84.6 to 91.8) for the arthroscopic group; p = 0.17. Recurrence rates at two years were significantly different: 11% in the open group and 23% in the arthroscopic group (p = 0.05). Recurrent instability was more likely in patients with a preoperative Hill-Sachs lesion and in male patients who were twenty-five years old and younger. There was no significant difference in shoulder motion between the groups at two years. CONCLUSIONS There was no difference between open and arthroscopic repair in terms of patient quality of life. Open repair resulted in a significantly lower risk of recurrence. Secondary outcome data from this trial suggest that open surgical repair may be recommended to reduce the risk of recurrent instability in younger male patients with a Hill-Sachs lesion.
The neuropeptide cortistatin attenuates experimental autoimmune myocarditis via inhibition of cardiomyogenic T cell‐driven inflammatory responses

Myocarditis is an inflammatory and autoimmune cardiovascular disease that causes dilated myocardiopathy and is responsible for high morbidity and mortality worldwide. Cortistatin is a neuropeptide produced by neurons and cells of the immune and vascular systems. Besides its action in locomotor activity and sleep, cortistatin inhibits inflammation in different experimental models of autoimmune diseases. However, its role in inflammatory cardiovascular disorders is unexplored. Here, we investigated the therapeutic effects of cortistatin in a well‐established preclinical model of experimental autoimmune myocarditis (EAM).
KIDNEY DENERVATION COMBINED WITH ELIMINATION OF ADRENAL–RENAL PORTAL CIRCULATION PREVENTS THE DEVELOPMENT OF HYPERTENSION IN SPONTANEOUSLY HYPERTENSIVE RATS

1. Kidney denervation in spontaneously hypertensive rats (SHR) during the prehypertensive stage delays and attenuates the development of hypertension. The same results have been obtained after elimination of the adrenal–renal portal circulation (ARPC). The aim of the present study was to investigate the influence of concomitant kidney denervation and elimination of ARPC on hypertension in SHR.
Survivin Expression in Tuberous Sclerosis Complex Cells

Tuberous Sclerosis Complex (TSC) is a tumor suppressor gene disorder with mutations of TSC1/TSC2 genes. This leads to the development of hamartomas that most frequently affect central nervous system, kidney, and skin. Angiomyolipomas are abdominal masses made up of muscle vessels and adipose tissues that grow mostly in proximity to kidneys and liver. Bleeding and kidney failure are the major justification for surgery. This study shows that angiomyolipoma-derived human smooth muscle TSC2−/− cells express the apoptosis inhibitor protein survivin when exposed to IGF-1. Survivin expression is also triggered whenever culture conditions perturb normal TSC2−/− cell function, such as the omission of EGF from the growth medium, the supplementation of anti-EGFR, blockade of PI3K and ERK, or inhibition of mTOR. Interestingly, single or simultaneous inhibition of PI3K by LY294002 and ERK by PD98059 does not prevent IGF-1-mediated survivin expression. Apoptogenic Smac/DIABLO, which is constitutively expressed by TSC2−/−A+ cells, is down-regulated by IGF-1 even in the presence of LY294002 and PD98059. These cells release IGF-1 by means of a negative feedback-regulated mechanism that is overrun when they are exposed to antibodies to IGF-1R, which increases the released amount by more than 400%. The autocrine release of IGF-1 may therefore be a powerful mechanism of survival of the tightly packed cells in the thick-walled vessels of TSC angiomyolipoma and in lymphangioleiomyomatosis (LAM) nodules. Future experimental therapies for TSC and LAM may result from the targeted inhibition of survivin, which may enhance sensitivity to TSC2 therapy.
Induction of platelet formation from megakaryocytoid cells by nitric oxide

Although the growth factors that regulate megakaryocytopoiesis are well known, the molecular determinants of platelet formation from mature megakaryocytes remain poorly understood. Morphological changes in megakaryocytes associated with platelet formation and removal of senescent megakaryocytes are suggestive of an apoptotic process. Previously, we have established that nitric oxide (NO) can induce apoptosis in megakaryocytoid cell lines. To determine whether there is an association between NO-induced apoptosis and platelet production, we exposed Meg-01 cells to S-nitrosoglutathione (GSNO) with or without thrombopoeitin (TPO) pretreatment and used flow cytometry and electron microscopy to assess platelet-sized particle formation. Meg-01 cells treated with TPO alone produced few platelet-sized particles (<3% of total counts), whereas treatment with GSNO alone produced a significant percentage of platelet-sized particles (22 ± 4% of total counts); when combined with TPO pretreatment, however, GSNO led to a marked increase in platelet-sized particle production (48 ± 3% of total counts). Electron microscopy confirmed that Meg-01 cells treated with TPO and GSNO yielded platelet-sized particles with morphological features specific for platelet forms. The platelet-sized particle population appears to be functional, because addition of calcium, fibrinogen, and thrombin receptor-activating peptide led to aggregation. These results demonstrate that NO facilitates platelet production, thereby establishing the essential role of NO in megakaryocyte development and thrombopoiesis.
Simultaneous Measurement of NH(4) Absorption and N(2) Fixation by Glycine max L. : RESPONSE TO TEMPERATURE, pH, AND EXTERNAL NITROGEN CONCENTRATION.

Ammonium absorption rates by intact nodulated and unnodulated soybean plants (Glycine max [L.] Merr., Amsoy 71) were determined from the liquid phase of a mist assay chamber. From the gas phase, simultaneous measurements of acetylene reduction rates were made from nodulated plants. Ammonium absorption capacity was consistently greater in unnodulated plants.At the beginning of flowering, plant roots were sprayed with an uptake solution ranging from 0.05 to 1.0 millimolar NH(4)Cl, and root nodules concurrently were exposed to 0.12 atmosphere acetylene. The NH(4) (+) absorption system of both nodulated and unnodulated plants were nearly saturated at 0.3 to 0.5 millimolar NH(4) (+). Increasing the pH from 4.0 to 6.8 stimulated NH(4) (+) absorption rate in both flowering and preflowering nodulated and unnodulated plants. Acetylene reduction rate was not altered by short-term exposure to increased acidity. Short-term exposure to lower absorption solution temperatures from 32 degrees C to 18 degrees C did not significantly affect NH(4) (+) absorption rate in flowering nodulated or unnodulated plants. However, acetylene reduction rate increased as the absorption solution temperature increased. The Q(10) value was 1.5 for the reaction rate. Increasing external NO(3) (-) concentration from 0.1 to 5.0 millimolar NO(3) (-) did not significantly influence the kinetics of NH(4) (+) absorption or acetylene reduction rate.
Microbiome dynamics in early life stages of the scleractinian coral Acropora gemmifera in response to elevated pCO2

Reef-building corals are complex holobionts, harbouring diverse microorganisms that play essential roles in maintaining coral health. However, microbiome development in early life stages of corals remains poorly understood. Here, microbiomes of Acropora gemmifera were analysed during spawning and early developmental stages, and also under different seawater partial pressure of CO2 (pCO2 ) conditions, using amplicon sequencing of 16S rRNA gene for bacteria and archaea and of ITS2 for Symbiodinium. No remarkable microbiome shift was observed in adults before and after spawning. Moreover, microbiomes in eggs were highly similar to those in spawned adults, possibly suggesting a vertical transmission from parents to offspring. However, significant stage-specific changes were found in coral microbiome during development, indicating that host development played a dominant role in shaping coral microbiome. Specifically, Cyanobacteria were particularly abundant in 6-day-old juveniles, but decreased largely in 31-day-old juveniles with a possible subclade shift in Symbiodinium dominance from C2r to D17. Larval microbiome showed changes in elevated pCO2 , while juvenile microbiomes remained rather stable in response to higher pCO2 . This study provides novel insights into the microbiome development during the critical life stages of coral.
Herding Behavior Post Initial Public Offering In Indonesia Stock Exchange

This research was conducted to test whether there is a herding behavior post Initial Public Offering (IPO) in Indonesia Stock Exchange. Domestic transactions on the Indonesia Stock Exchange are rising year by year along with the increased of IPO emissions. The existence of underpricing phenomenon causes a domino effect (herding) that arises on potential investors after the IPO. This study used Cross-Sectional Absolute Deviation (CSAD) method to detect herding behavior. The data used were daily price data of IPO shares from the 1st day until the 30th day after IPO period 2005-2015. Hypothesis testing was done using regression analysis by means of CSAD variable as dependent variable and return market as independent variable. The result of this research indicated that there was a herding behavior post -IPO in Indonesia Stock Exchange period 2005-2015 period. It is shown by the negative and significant value of γ2 (0.013 <0.05).
Crohn's Disease and Month of Birth

Background: Environmental factors trigger the onset of inflammatory bowel disease (IBD) in genetically predisposed individuals. Exposure to seasonal external factors during the maturation of the immune system is suspected to be an inducing factor for IBD. Some studies suggested an association between the month of birth and the later development of IBD. We studied this putative relationship in a large cohort of Belgian patients with Crohn's disease (CD). Methods: Data from 1025 patients born between 1935 and 1990 were collected. Diagnosis of CD was based on generally accepted clinical, endoscopic, and histologic criteria. As a control group, a cohort of 5125 non‐IBD patients seen at the same hospital and matched for birth year and sex was used. Odds ratios were calculated using multivariate unconditional logistic regression including the matching variables and allowing for cyclic variation in risk with month of birth. Results: A cyclic pattern described by a 4‐month periodic function was observed with peaks in April and August. Moreover, being born in June significantly reduced the risk of developing CD later in life (P = 0.012). Conclusion: In this Belgian cohort, a significant association was found between the month of birth and later development of IBD; a significant reduced risk to develop CD was observed for people born in June. Moreover, environmental yearly reoccurring factors during pregnancy or postpartum might be associated with the occurrence of CD later in life.
Concurrent loss of chromosome arm 1p and chromosome 3 predicts a decreased disease-free survival in uveal melanoma patients.

PURPOSE Uveal melanoma is a highly malignant disease with a mortality rate of 50% at 10 to 15 years. Previous studies have shown that chromosomal changes are associated with decreased survival of the patient. However, in these studies the small number of tumors analyzed did not allow robust statistical analysis. In the present study, the independent numerical changes in chromosomes 1, 3, 6, and 8 on disease-free survival (DFS) was assessed in a large series of patients with uveal melanoma. METHODS One hundred twenty tumors from patients with uveal melanoma were analyzed for numerical changes in chromosomes 1, 3, 6, and 8, with cytogenetic analysis, fluorescent in situ hybridization, and/or comparative genomic hybridization. Data were correlated with disease outcome in univariate and multivariate analyses, by Kaplan-Meier and Cox regression analyses. RESULTS At a mean follow-up time of 45 months, 42 patients had died or had metastatic disease. In the univariate analysis, loss of chromosome 3, gain of 8q, largest tumor diameter, or the presence of epithelioid cells was associated with a decreased DFS. In the multivariate analysis, the effect of monosomy 3 on survival was largely modified by changes in 1p36. Regarding all chromosomal changes, only the concurrent loss of the short arm of chromosome 1 and all of chromosome 3 was an independent prognostic parameter for disease-free survival (P < 0.001). CONCLUSIONS In uveal melanoma, concurrent loss of the short arm of chromosome 1 and all of chromosome 3 is an independent predictor of decreased DFS.
The effect of breastfeeding on childhood overweight and obesity: A systematic review of the literature

Background: Childhood obesity has reached epidemic proportions. There is increasing attention to the topic of prevention and continued debate as to whether breastfeeding (BF) is protective against childhood obesity. Previous systematic reviews on this topic were done in 2005 showing that BF was protective against childhood obesity but, because of confounding variables, the evidence was weak. Objective: To explore the current evidence of the effect of BF on childhood obesity and provide recommendations for the nurse practitioner (NP) as a primary care provider. Methods: A systematic review of the literature from 1/2005 to 3/2012 was done to assess the evidence on the relationship between BF and childhood obesity. Results: The majority of studies identified in this article showed a relationship between BF and obesity prevention, but because of confounding maternal, child, cultural, genetic, and environmental variables, the relationship remains unclear. Conclusions: While it is possible that there are protective benefits of BF on childhood obesity, it is difficult to prove because of confounding variables. However, because of other benefits for the mother and child, BF should be encouraged. Whether obesity in childhood can be prevented by BF remains unclear. Further research controlling for confounding variables is needed to provide concrete evidence.
The integration of character education in local tradition: an ethnographic study

The significance of character education has becoming an appealing issue to be discussed. Its significance has been brought to school through a number of practices. In fact, character education is not merely the result of schooling but this is a widespread from integration of character education in local culture. This present study attempts to explore character values contained within a local genius called subak pancoran. Further, this study is a qualitative study by utilizing ethnographic design. It was conducted in Buleleng regency, Bali. There are three ways that the researcher uses to collect the data, namely interview, observation sheet, and field notes. The subjects are selected purposefully. Accordingly, the collected data are analysed qualitatively. This study reveals that subak pancoran tradition emphasis on the following characters; tolerance, religious, democratic, communicative, hard work, responsible, mutual help, and environmental awareness. The children character development cannot be separated from the culture where children live and grow. The contribution of this study to the board of knowledge will also be added.