Miracle-dz/UniFAR-FTUs huggingface dataset:
HtrA is the unique surface housekeeping protease in Lactococcus lactis and is required for natural protein processing

We identified an exported protease in Lactococcus lactis ssp. lactis strain IL1403 belonging to the HtrA/DegP family. Inactivation of the chromosomal gene (htrALl) encoding this protease (HtrALl) results in growth thermo‐sensitivity at very high temperatures (above 37°C for L. lactis). The role of htrALl in extracellular proteolysis under normal growth conditions was examined by testing the stability of different exported proteins (i.e. fusions, a heterologous pre‐pro‐protein or a native protein containing repeats), having different locations. In the wild‐type (wt) strain, degradation products, including the C‐terminal protein ends, were present in the medium, indicating that proteolysis occurs during or after export to the cell surface; in one case, degradation was nearly total. In contrast, proteolysis was totally abolished in the htrA strain for all five proteins tested, and the yield of full‐length products was significantly increased. These results suggest that HtrALl is the sole extracellular protease that degrades abnormal exported proteins. In addition, our results reveal that HtrALl is needed for the pro‐peptide processing of a natural pro‐protein and for maturation of a native protein. We propose that in lactococci, and possibly in other Gram‐positive organisms with small sized‐genomes, a single surface protease, HtrA, is totally responsible for the housekeeping of exported proteins.
IFRS Adoption Effects in Greece: Evidence from the IT Sector

From January 2005 all the listed firms in the EU member states were required to prepare their financial statements according to the International Financial Reporting Standards – IFRS. In Greece, this transition from Greek GAAP to IFRS may have an effect on firms’ financial results. This study examines the possible impact of adoption of IFRS at Greek firms of the Information Technology (IT) sector, listed on the Athens Exchange. For this reason, the study analyses the financial statements of the sample firms for three years before and after the IFRS adoption in Greece with some ratios. Also, a further analysis is applied in order to estimate the exact influence of IFRS adoption effects in a different time interval and is compared the year 2002 (the year that was firstly announced the IFRS adoption in E.U.) with the year 2005 (the first year of IFRS official adoption on firms’ financial statements). The received results reveiled that, concerning the IFRS adoption effects, compared the year 2002 with the year 2005, as none of the accounting ratios had a statistically significant change due to the IFRS adoption, there is no evidence for a specific impact of the adoption of IFRS on accounting-based information and performance from financial statements at the sample firms. In contrary, in examining the data for the sample firms over a threeyear-period before and after the IFRS adoption, the results revealed that two (EBIT margin; gearing) out of twenty accounting ratios had a statistically significant change and a positive impact due to the IFRS adoption.
Cognitive profiles associated with intracranial dural arteriovenous fistula.

SIR—There are a number of case studies and small case series of intracranial dural arteriovenous fistula (DAVF) associated with cognitive impairment sufficient to amount to a dementia syndrome, with resolution of cognitive deficits following definitive treatment (surgical, endovascular) of the fistula [1–19]. Thus intracranial DAVF is recognised as a rare cause of reversible vascular dementia, through a presumed mechanism of intracerebral venous hypertension. However, accounts of the precise neuropsychological deficits in these patients and serial documentation of cognitive function are largely lacking, most reports focusing on the neuroradiology of the vascular anatomy and endovascular intervention. This may be due in part to the necessity for prompt therapeutic intervention when there is acute neurological deterioration [5], although at least some intracranial DAVF cases are associated with slowly progressive cognitive decline sufficient to suggest an initial differential diagnosis of neurodegenerative dementia [8, 9, 15, 16]. The label of ‘thalamic dementia’ has been used on occasion, based largely on neuroimaging findings of bilateral thalamic involvement [10, 17, 18]. Our experience with three cases of intracranial DAVF [20] has included serial monitoring of cognitive function, either with formal neuropsychological assessment or the Addenbrooke's Cognitive Examination (ACE) [21], a ‘bedside’ test which incorporates the Mini-Mental State Examination (MMSE) [22] and with which we have extensive experience [23]. As the clinical and neuroradiological details of these cases have been previously reported, only the cognitive findings are given here.
Flutamide-induced hepatotoxicity during treatment of acne-A case report

Flutamide is a non-steroidal anti-androgenic drug used in the treatment of prostate cancer, acne and hirsutism. Some cases of severe flutamide-induced hepatotoxicity have been reported in the literature. We report the case of a 21-year-old female who presented with a significant increase of aminotransferase levels during the treatment of acne with flutamide, which resolved completely after discontinuation of the drug. We discuss the diagnosis, the risk/benefit ratio, and conclude that monitoring liver function tests is mandatory and that the drug should be discontinued if an increase in aminotransferase levels occurs, due to the possibility of severe liver dysfunction.
A low loss, 5.5 GHz-20 GHz monolithic balun

A low-loss monolithic Marchand balun has been designed and fabricated using polyimide as the inter-metal dielectric. The measured return loss is less than -10 dB from 5.5 GHz to 28 GHz. The balun loss is less than 0.7 dB over the 6 GHz to 21 GHz operating band. This is the lowest loss ever reported for such a balun. The excellent loss is the result of using a relatively thick polyimide layer (10 /spl mu/m) as the inter-metal dielectric. This balun has been applied to HBT and pHEMT amplifiers with second harmonic components suppressed >40 dB, even in compression, demonstrating very good push-pull operation.
Antecedents of intention and usage toward customers’ mobile commerce: Evidence in Vietnam

Abstract This study seeks to discover the underlying drivers that can influence Vietnamese consumers’ adoption of mobile commerce. We extended the traditional Technology Acceptance Model (TAM) by integrating the quality dimensions, personal innovativeness, playfulness and cost factors. Based on the theoretical background, a hypothetical research model and research hypotheses were developed and tested by using data collected from the questionnaire survey. The results showed that, across hedonic and utilitarian tendencies, consumers in Vietnam are not willing to pay for mobile commerce, even if the service is useful and easy to use. This result is consistent with the findings of previous studies in China and Malaysia, which have the same developing country context as Vietnam. This study is also undertaken to evaluate the moderating role of utilitarian and hedonic tendencies toward mobile commerce usage, to provide insights for service providers in order to formulate specific products or applications that match with and satisfy customers’ needs better than those of their competitors. Managerial implications and limitations of the study results are also discussed.
Hotel Customer Expectations of Service: A Provincial Analysis of Family Business inChiangmai, Thailand

Hotel Customer Expectations of Service: A Provincial Analysis of Family Business in Chiangmai, Thailand It is essential for service providers in the hospitality industry to comprehend what customers of various market segments expect from a service firm in order to deliver high quality services. This study aims at measuring and comparing differences in the desired service quality expectations of hotel customers, as well as identifying the service dimensions that matter most to hotel guests. To achieve this, a modified SERVQUAL scale was employed as the research instrument.
The Importance of Functional Morphology for Fishery Conservation and Management: Applications to Hawaiian Amphidromous Fishes

The functional capabilities of species can have a strong effect on their ability to maintain sustainable populations in anthropogenically altered environments. This is especially true among species comprising freshwater ichthyofaunas on small oceanic islands, where fishes frequently traverse boundaries between different ecosystems. Many aspects of functional performance in fishes relate directly to morphological features and limitations. In this review, we use the ichthyofauna of the Hawaiian Islands as an example to demonstrate how the habits, habitat, and in-stream distribution of five amphi-dromous fish species relate to the functional morphology of locomotion and feeding. Furthermore, we evaluate how performance limitations related to functional morphology might affect each species under changing environmental conditions. Based on this analysis we make four key recommendations. (1) Hawaiian stream management plans need to be tailored to island-specific conditions. (2) Estuaries need to be studied as a critical habitat because of the interface between fishes and human populations in these areas. (3) New recruits of Sicyopterus stimpsoni might serve as a key indicator species to monitor long-term health of Hawaiian estuaries. (4) The broad use of the Index of Biological Integrity (IBI) to assess Hawaiian stream health needs to be critically evaluated.
Opinion and expectation of the community who come to the parks for doing sports (applications in Gaziantep).

This study was prepared to determine the opinions and expectations of the community who come to the parks for doing sports. The popoulation consists of the people who come to parks in Gaziantep for doing sports. Including 480 female and 372 male totally 852 people participated to resarch. Survey method (scanning) and the views and expectations survey which was developed by Tatli was used for the study. A total number of 852 people, 480 women and 372 men, participated in the research. SPSS 18 statistical packaged software used for analysis of the datas obtained. To comment the results percentage, frequency distribution and X² technique were used. The research results indicated that people come to the parks and doing sport for living a healhty lifestyle, they prefer parks because of free charge and they feel healthy and spry after doing sport. High incidence of the participants want to study with a personal trainer, when consulted by gender women are doing sports to ensure weight control, while men want to do bodybuilding. There is not a significant relation between wish to do sport with a personal trainer and occupational group and when examined the relation between educational status and preference to do sports in parks, it is concluded that primary and secondary school graduates prefer parks because their childen can play in the park while they are doing sport, high school graduates prefer parks because gyms have environment and hygiene problems, university graduates and above prefer parks beacuse gym membership fees are high.
Managing Word of Mouth Communications

Examines the importance of the verbal exchange of positive and negative information about a firm′s products and services. Presents suggestions for learning what is being said and how to gain systematic control over the word of mouth process. Suggests a model of this process, including interpersonal communications among a variety of stakeholder groups. Highlights the case of the hospitality industry, but makes suggestions of use to all service businesses.
Some Personality Correlates of Obese Persons

16 obese patients in a volunteer program of weight reduction were given the Adjective Check List (ACL) and the Edwards Personal Preference Schedule (EPPS) prior to beginning weight reduction. The patients were from 64.6% to 214.7% overweight. It was predicted that they would score lower than the normative group on the Achievement, Affiliation, Dominance, Endurance, Order, Personal adjustment, and Self-control scales, while higher scores were predicted for the Aggression, Exhibitionism, Heterosexuality, and Intraception scales. The predictions were upheld. In addition, the obese sample checked a significantly fewer number of Favorable Adjectives than did the normative group and more descriptive adjectives pertaining to Autonomy.
Land cover classification by using multi-temporal COSMO-SkyMed data

The objective of this paper is to report on the crop classification activities carried out during the first year of the Italian project “Use of COSMO-SkyMed data for LANDcover classification and surface parameters retrieval over agricultural sites” (COSMOLAND), funded by the Italian Space Agency. The project intends to contribute to the COSMO-SkyMed mission objectives in the agriculture and hydrology application domains. In particular, the objective of the classification activities is to assess the potential of multi-temporal series of X-band COSMO-SkyMed SAR data for crop classification. The selected agricultural site is located in the Capitanata plain close to the Foggia town (Puglia region, Southern Italy). Over this area, 8 Stripmap PingPong COSMO Sky-Med images at HH/HV polarization and at low incidence angle were acquired from April to August 2010. In the paper, a classification scheme based on the Maximum Likelihood algorithm is applied to the multi-temporal data set and its accuracy is assessed with respect to a reference map obtained by means of SPOT data.
Drug-Induced Thrombocytopenia in the Critically Ill

Background:Drugs are suspected when obvious causes of intensive care unit (ICU)-acquired thrombocytopenia have been excluded. It has been estimated that 10% to 25% of cases may be drug induced. Objectives: The objectives of this study were to evaluate the risk of thrombocytopenia associated with drug classes commonly used in the ICU. Methods: Data concerning patients admitted for more than 48 hours between 1997 and 2011 were extracted from a research-purpose database. Patients with thrombocytopenia within the first 72 hours of admission and with diagnoses or interventions considered strongly associated with thrombocytopenia were excluded. Drug exposures were compared and adjusted for confounders using conditional logistic regression. Results: A total of 238 cases were identified after exclusions. Each case was matched according to sex, age, admission year, and admission unit with 1 control. In univariate analysis, quinolones (odds ratio [OR] = 1.56; 95% CI = 1.01-2.40) and extended spectrum β-lactams (OR = 1.71; 95% CI = 1.00-2.93) were significantly associated with an increased risk of thrombocytopenia. After adjusting for confounders, exposure to quinolones was the only drug class with a statistically significant increase in risk of thrombocytopenia (OR = 1.697; 95% CI = 1.002-2.873; P = 0.049). Conclusion: In this study of ICU-acquired thrombocytopenia, we found no association between the exposures to several antibiotic classes, anticonvulsants, antiplatelet agents, nonsteroidal anti-inflammatory agents, and heparins and thrombocytopenia. As linezolid was not studied, no conclusions can be drawn concerning this agent. The statistically significant association between quinolones and thrombocytopenia warrants further investigation.
The environmental practice of resorts and tourist loyalty: the role of environmental knowledge, concern, and behaviour

Abstract This study investigates the moderating effects of environmental knowledge, environmental concern, and the direct and indirect environmental behaviours of tourists, on the relationship between the environmental practices of resorts and tourists’ loyalty. The respondents were 529 guests of lake and river resorts in Peninsular Malaysia. The data were analysed using the partial least squares technique. The findings indicate that the effect of resorts’ environmental practices on loyalty is greater among tourists who have a higher level of environmental concern and who behave directly or indirectly in a more environmentally friendly manner. However, environmental knowledge has no moderating effect. The study provides useful information for resort managers to improve their environmental practices and increase tourists’ environmental concern and behaviour.
Crystal Structure of a Voltage-gated K+ Channel Pore Module in a Closed State in Lipid Membranes*

Background: Structures of functional K+ channels in lipid membranes are lacking. Results: We dissected the pore module from the intact subunit, demonstrated its functional competence, and determined its crystal structure in membranes. Conclusion: The structure is unprecedented, because it embodies a transient conformation trapped between closed and open states. Significance: The findings highlight the deterministic role of surface match between sensor and pore underpinning their functional coupling. Voltage-gated K+ channels underlie the electrical excitability of cells. Each subunit of the functional tetramer consists of the tandem fusion of two modules, an N-terminal voltage-sensor and a C-terminal pore. To investigate how sensor coupling to the pore generates voltage-dependent channel opening, we solved the crystal structure and characterized the function of a voltage-gated K+ channel pore in a lipid membrane. The structure of a functional channel in a membrane environment at 3.1 Å resolution establishes an unprecedented connection between channel structure and function. The structure is unique in delineating an ion-occupied ready to conduct selectivity filter, a confined aqueous cavity, and a closed activation gate, embodying a dynamic entity trapped in an unstable closed state.
Interaction of Bdellovibrio bacteriovorus and Host Bacteria II. Intracellular Growth and Development of Bdellovibrio bacteriovorus in Liquid Cultures

The intracellular life cycle of Bdellovibrio bacteriovorus 109 growing on Escherichia coli in a dilute nutrient medium exhibits a period of constant infective titer while the parasite grows and elongates inside the host cell. This period is terminated after 2 to 4 hr, and the number of the plaque-forming units in the culture rises rapidly to as much as six times the initial titer. The growth pattern of Bdellovibrio is similar with actively growing or resting host cells, or with host cells killed by ultraviolet irradiation or by heating at 70 C. The yield of B. bacteriovorus strain 109 in two-membered cultures with E. coli B depends on the host concentration and may reach 7.5 × 1010 cells per ml. Penicillin, which has no effect on the attachment and penetration of Bdellovibrio, inhibits its multiplication.
Extending relationship value: observations from a case study of the Canadian structural wood products industry

Purpose – The purpose of this paper is to present how the construct of relationship value (RV) has the potential to help suppliers understand how to create superior value in their customer relationships and ultimately improve their competitiveness. Nowhere is this truer than in the Canadian wood products industry, where sales to its most important market, the USA, have recently been dwindling. The paper seeks to present how RV was adapted in this research context and extended over elements of scope, range of potential applications, scale of measurement, and computational techniques.Design/methodology/approach – A multiple‐case study was undertaken and consisted of the evaluation of 58 customer relationships for three wood products manufacturers.Findings – Findings highlight the necessary distinction between “value for” and “value of” customers when measuring relationship value from a supply perspective. Based on the value and orientation of exchange, a new segmentation of customer relationships emerges wh.
Shareholder Lock-In Contracts: Share Price and Trading Volume Effects at the Lock-In Expiry

This paper unveils the diversity in lock-in agreements of firms listed on the Nouveau Marche stock exchange in France.We give the main economic reasons why shareholders adopt lock-in agreements that are more stringent than legally required.We relate the abnormal returns and the abnormal volume at the expiry dates of the different types of lock-in contracts to the degree of underpricing, venture-capitalist reputation and underwriter reputation.Abnormal returns and trading volume increase at the lock-in expiry; this is especially pronounced at the expiry dates of insider lock-in contracts as insiders are legally required to be locked-in.We do not find significant abnormal returns at the expiries of VC contracts, even though trading volume increases at their lock-in expiry.There is also no evidence of a positive (negative) relation between abnormal returns (abnormal volume) and more stringent lock-in contracts.Lock-in contracts and the degree of underpricing are complementary signalling devices.
Security, Risk, and Trust in Individuals' Internet Banking Adoption: An Integrated Model

The fact that trust has a specific influence upon individualsâ€™ adoption of internet banking has been proven in previous research. However, only few cues about the related evaluation of trust in the online environment are provided and the definition of trust is still ambiguous. Therefore, an integrated SRT (Security-Risk-Trust) model is proposed in this research to explain (1) the relationships among trust and the other highly relevant factors, perceived security and perceived risk; as well as (2) the effects of the above three factors on individualsâ€™ adoption of internet banking. An empirical study is accordingly conducted and the data comes from three universities in north Taiwan, and includes 188 students and faculty. Two results are obtained: first is that perceived security is an important antecedent of trust and perceived risk; second is that perceived security has both direct and indirect effects upon individualsâ€™ adoption of internet banking. Hence, we suggest that the management of internet banking should put more emphasis on implementing novel information security mechanisms and marketing methods to increase individualsâ€™ perceived security, which is crucial to their internet banking adoption. To cite this document: Chorng-Shyong Ong and Yi-Luen Lin, "Security, risk, and trust in individualsâ€™ internet banking adoption: An integrated model", International Journal of Electronic Commerce Studies, Vol.6, No.2, pp.343-356, 2015. Permanent link to this document: http://dx.doi. org/10.7903/ijecs.1428
ScienceDirect Emerging Markets Queries in Finance and Business 2013 The effects of IFRS on net income and equity : evidence from Romanian listed companies

IFRS adoption in Europe represents a major milestone towards financial convergence and Romania, as European member state, had in the last few years a positive reaction towards this process. Starting with year 2012, Romania imposed trough its national regulatory body (the Ministry of Finance) the presentation of individual financial statements according to IFRS for 67 Romanian listed companies. The main concern has been to understand the most important differences between national accounting rules and IFRS and how these could affect their reported performance. The goal of the paper is to address this concern by highlighting some empirical evidence of the differences between Romanian accounting regulation and IFRS. These differences are identified in the reconciliation of shareholders’ equity and net income of the Romanian listed companies in order to present the significant impacts of the conversion to IFRS. The conclusion of this study is that for all 67 companies, presented in our study, the application of IFRS had a small effect on net income and shareholders’ equity. © 2013 Published by Elsevier Ltd. Selection and peer review under responsibility of Emerging Markets Queries in Finance and Business local organization