Miracle-dz/UniFAR-FTUs huggingface dataset:
Which bowel preparation is best? Comparison of a high-fibre diet leaflet, daily microenema and no preparation in prostate cancer patients treated with radical radiotherapy to assess the effect on planned target volume shifts due to rectal distension.

OBJECTIVE We evaluated and compared a high-fibre diet leaflet, daily microenema and no preparation to establish how best to achieve consistent bowel preparation in prostate cancer patients being treated with radical radiotherapy. METHODS 3 cohorts of 10 patients had different dietary interventions: no bowel preparation, high-fibre diet information leaflet and daily microenemas. The available cone beam CT (CBCT) scans of each patient were used to quantify interfractional changes in rectal distension (measured using average cross-sectional area-CSA), prostate shifts relative to bony anatomy compared with that at CT planning scan and rates of geometric miss (i.e. shifts of ≥5 mm). 85 CBCT scans were available in the pre-leaflet cohort, 89 scans in the post-leaflet, and 89 scans in the post-enema group. RESULTS Mean rectal CSA in the post-enema group was reduced compared with both pre-leaflet (p=0.010) and post-leaflet values (p=0.031). The magnitude of observed mean prostate shifts was significantly reduced in the post-enema group compared with the pre-leaflet group (p=0.014). The proportion of scans showing geometric miss (i.e. shift >5 mm) in the post-enema group (31%) was significantly lower than in the pre-leaflet (62%, p<0.001) or post-leaflet groups (56%, p<0.001). CONCLUSION This study indicates microenema to be an effective measure to achieve reduction in rectal CSA, prostate shift and reduce geometric miss of ≥5 mm. A further prospective randomised study is advocated to validate the results. ADVANCES IN KNOWLEDGE The use of microenema is effective in reducing prostate shift and rectal CSA, consequently decreasing the incidence of geographical miss.
Vascularized Fibula-Based Physis Transfer for Pediatric Proximal Humerus Reconstruction

Summary: Free vascularized fibular transfer has become a standard procedure in upper extremity reconstruction after resection of osteogenic tumors. The authors present two rare pediatric cases of high-grade osteosarcoma resection of the proximal humerus. A free vascularized fibula autograft including the physis based on the anterior tibial artery and vein was used for reconstruction in a delayed (case 1) and immediate (case 2) approach. The main focus of the article is to describe the surgical technique, which is also presented in a series of intraoperative videos. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, V.
Revised Ms . # R-00112-2008 MECHANISM OF ESTROGEN-MEDIATED INTESTINAL PROTECTION FOLLOWING TRAUMA-HEMORRHAGE : p 38 MAPK-DEPENDENT UPREGULATION of HO-1

Please address correspondence, proofs and reprints requests to: Dr. Irshad H. Chaudry Center for Surgical Research University of Alabama at Birmingham G094 Volker Hall 1670 University Boulevard Birmingham, AL 35294-0019 Phone: 205-975-2195 Fax: 205-975-9719 E-mail: Irshad.Chaudry@ccc.uab. edu Page 1 of 34 Articles in PresS. Am J Physiol Regul Integr Comp Physiol (April 23, 2008). doi:10.1152/ajpregu.00112. 2008
A COMPARISON OF TWO GROUPS OF WOMEN WITH BULIMIA NERVOSA ON SYMPTOMONSET

Bulimia nervosa (BN) is a significant mental health problem for women. Both children and adolescents develop risk factors for BN that are identifiable. An important role for psychiatric-mental health nurses is the prevention of psychiatric disorders through risk factor identification and intervention for early symptoms. The purpose of this study was to extend recent research on the sequencing of risk factors and symptoms in the development of bulimia nervosa. Symptom history was collected on 71 women who agreed to participate in research on eating disorders (EDs). Women were divided into two groups based on whether their first symptom manifested was bingeing (BF) or dieting (DF). The groups were compared on age of symptom onset, weight history, and history of diagnosis. There were significant differences between the groups, and the present findings contradict some of the important conclusions from three previous studies. The results are discussed and implications for strategies for early detection and prevention are presented.
IT Conflict Contagion : Action Research in a Consulting Firm

User conflicts and resistance behaviours represent one of the major managerial difficulties during Information Systems (IS) implementation. Although numerous IS studies tackle user resistance and conflicts by anticipating, minimising or even amplifying these negative behaviours, little research has taken into consideration the contagion mechanisms of conflicts and examined why and how users similarly resist to entirely different Information Technology (IT) projects. The IS literature is sparse on addressing the impact of resistance behaviours that occurred in the past on the new IT. IS managers need to anticipate potential causes for project failure because of ongoing resistance behaviours toward the new IT, but also because of resistance behaviours occurred in the past and persist until today, or are likely to reappear. For IS researchers and practitioners, my research gives greater attention to issues related to current and prior conflicts occurring in a firm’s IT project portfolio. Therefore, we particularly mobilise the theories of contagion and Inoculation which have been so far weakly used in the field of information systems. The empirical part consists of a three-year action research project conducted at Efficient Innovation Corporation (a French management consulting firm). Firstly, my observations reveal that employees expressing task-oriented conflicts towards an IT deployment project were likely to use a bypassing strategy, hiding socio-political conflicts. Secondly, we were able to identify a phenomenon of conflict contagion between two IT projects despite their strong differences in terms of objectives, functional perimeters and users. Thirdly, the "Inoculation" techniques that we implemented succeeded to stall and limit the diffusion of resistance behaviours toward IT. The underlying message of this thesis is to consider prior resistance behaviours and conflict contagion as key processes integrated into IT implementation. Accordingly, we introduce the concept of "Resistance Path Dependency", and propose a conceptual model of possible conflict contagion mechanisms between different teams and IT projects.
Quantitative estimation of annual runoff variation from the Hotan River, China.

Starting from the existing analysis of runoff from the Hotan River, the varying cause of runoff in the Hotan River is analyzed using the annual runoff accumulated curves and the orderly cluster method, pointing out that the runoff from the Hotan River coming from the mountains falls into the natural runoff with the fluctuations because of being subject to climate changes. It is worth noticing that the Xiaota annual runoff flowing into Tarim River was reduced by 0.322 billion m3 in comparison of the postior 1989 series with the prior 1989 series and under the join action by both human being activities and climate changes.
Does glucose level at hospital discharge predict one-year mortality in patients with diabetes mellitus treated with percutaneous coronary intervention for ST-segment elevation myocardial infarction?

BACKGROUND It has been shown that diabetes mellitus (DM) is an independent prognostic factor in patients with myocardial infarction (MI). In addition to that fact the prognostic significance of blood glucose (BG) abnormalities in the acute phase of MI has also been suggested. Recently, a new prognostic factor has been evaluated - the glucose level at hospital discharge. AIM To assess whether the glucose level at hospital discharge is associated with one-year mortality in patients with DM treated with percutaneous coronary intervention (PCI) for ST-segment elevation MI (STEMI), taking into account hypoglycaemic treatment. METHODS Consecutive patients with STEMI and DM treated with PCI, who survived hospitalisation, were included in the analysis. Patients were assumed to have DM if previous diagnosis of DM or newly diagnosed DM during hospital stay was noted. Criteria of newly diagnosed DM were as follows: fasting BG >or=7 mmol/l at least twice after acute phase of STEMI, BG >or=11.1 mmol/l in a 2-hour glucose tolerance test performed before discharge. Fasting plasma glucose at hospital discharge was used for analysis. RESULTS Out of 2762 consecutive patients with STEMI, 565 had DM. In-hospital mortality in this group was 9.4% (53 patients), so the final DM group consisted of 512 patients. After discharge 59 (11.5%) patients died during one-year follow-up. The glucose level at discharge was not an independent prognostic factor of one-year mortality in the whole analysed group, however insulin treatment at discharge was (HR 2.61, 95% CI 1.29-5.29; p=0.008). Afterwards, we undertook multivariate analysis separately in the group treated with insulin (253 patients) and in the group treated with oral drugs or diet only (259 patients). This analysis showed that in the group treated with insulin the glucose level at discharge was not an independent prognostic factor of one-year mortality (HR 1.07, 95% CI 0.95-1.22; p=0.27), whereas in patients treated with hypoglycaemic agents or diet it was significantly associated with a one-year mortality (HR 1.30, 95% CI 1.01-1.68; p=0.049). CONCLUSIONS 1. Patients with STEMI and DM treated with insulin at hospital discharge have higher risk of death, probably because of more advanced DM and more severe complications, than patients treated with oral drugs or diet. 2. Elevated glucose level at hospital discharge predict one-year mortality only in patients with MI and DM treated with oral drugs or diet.
Validating the relationship between trust, commitment, economic and non-economic satisfaction in South African buyer-supplier relationships

Purpose The paper aims to validate the relationship between satisfaction, trust and commitment in South African business buyer–supplier relationships. Satisfaction was looked at from the dual perspective of economic and non-economic satisfaction. Design/methodology/approach A research model showing hypothesised relationships between the constructs was tested using data collected from 250 large companies in South Africa. Structural equation modelling using AMOS software was used to analyse the data. The results provide support for the distinctiveness of both economic and non-economic satisfaction and the mediating effect of trust. Findings The findings show that economic satisfaction exerts a direct influence on trust, which, in turn, has a direct influence on commitment. Trust and commitment were both found to have a positive influence on non-economic satisfaction. Research limitations/implications The tested nomological network of business relationship quality dimensions validates some of the recent findings by Ferro et al. (2016) in the South African context of buyer–supplier relationships. Originality/value The study contributes to a better understanding of satisfaction and its relationship with other relationship quality constructs, especially in the context of large companies in South Africa.
Use of the transverse cerebellar diameter/abdominal circumference ratio in pregnancies at risk for intrauterine growth retardation

A prospective study was conducted to evaluate the ability of the transverse cerebellar diameter/abdominal circumference ratio to identify growth‐retarded fetuses. Of the cases analyzed, 48 of 87 (55%) were growth retarded by birth weight. The transverse cerebellar diameter/abdominal circumference ratio identified growth retardation with a sensitivity of 71%, specificity of 77%, positive predictive value of 79%, and negative predictive value of 68%. Fourteen growth‐retarded fetuses were missed by the ratio; however, 57% of the missed cases were severely growth retarded. The transverse cerebellar diameter/abdominal circumference ratio can be useful for the assessment of fetal growth retardation; however, the ratio may be normal in cases of severe fetal growth retardation. © 1994 John Wiley & Sons, Inc.
Relationship between paraoxonase‐1 activity, its Q192R genetic variant and clopidogrel responsiveness in the ADRIE study

*Division of Angiology and Hemostasis, Division of Endocrinology, Diabetology and Nutrition, Department of Medical Specialties, GenevaUniversity Hospitals and Faculty of Medicine, Geneva, Switzerland; Hematology Laboratory, §Division of Cardiology, Be´ziers Hospital, Be´ziers;–Hematology Laboratory, Montpellier University Hospital, Montpellier, France; **Division of Laboratory Medicine, Department of Genetics andLaboratory Medicine, Geneva University Hospitals, Geneva; and Division of General Internal Medicine, Geneva University Hospital and Facultyof Medicine, Geneva, SwitzerlandTo cite this article: Fontana P, James R, Barazer I, Berdague´ P, Schved JF, Rebsamen M, Vuilleumier N, Reng JL. Relationship betweenparaoxonase-1 activity, its Q192R genetic variant and clopidogrel responsiveness in the ADRIE study. J Thromb Haemost 2011; 9: 1664–6.
Trends in Avoidable Hospitalizations for Children in Florida from 1992 to 2003

&NA; This article examines trends in avoidable hospitalizations to determine whether improved access following post‐1997 Balanced Budget Act expansions in public health insurance programs resulted in a decreased rate among affected populations, particularly children of ages 0–19 years. Florida inpatient discharge data sets from 1992 to 2003 were compiled in order to analyze trends using descriptive and linear regression methods. The rate of avoidable hospitalizations for children was subsequently compared to that of adults (ages 20–64 years) to assess relative changes. The rate declined significantly for black and other nonwhite children. Based on age, the declines were concentrated in the subgroups for ages 0–1 year, 5–9 years, and 10–14 years. In contrast, the rate for adults, with the exception of nonwhite and black populations, increased. The decline in the overall rate of avoidable hospitalizations for children indicates that increased expenditures related to the expansions were at least partially offset. However, the trend could not be directly attributed to the Balanced Budget Act.
Lecturers’ Use of ICTs to implement the Curriculum at a Teacher Training College in Zimbabwe.

Typical job tasks entailed in implementing a college curriculum such as MS Power presentations in lectures, lecture preparation, research as well as teaching students at a distance require college lecturers in Zimbabwe to use ICTs. In most developed countries lecturers can now integrate ICTs in teaching. In Zimbabwe’s teacher training colleges not much research-based evidence exists about how lecturers cope with the considerably new technologies in their work. This study sought to obtain information on lecturers’ basic use of ICTs as a curriculum innovation that they should embrace in their work. The research employed the mixed-methods research design. I used questionnaires to collect data from a convenience sample of 100 lecturers and conducted interviews with five of the participants. A majority of lecturers indicated that they had irregular access to ICT facilities. They seldom or never used ICTs in their work. Focus group discussions revealed that inadequate ICT facilities including poor internet connectivity contributed to almost non-use of ICTs by most lecturers. Lecturers professed inadequate personal knowledge and skills to use a good number of the technologies. Findings of this study confirm the incidence of unsatisfactory use of basic ICT operations by lecturers at a college with meager functional ICTs. I recommend that the college provides enduring support to enable lecturers to evolve to the stage of proficient use of basic ICT operations for them to ultimately use ICTs for teaching.
Modern portfolio diversification using iShares: correlation and return gaps

This analysis shows that coefficient of correlation alone does not provide an intuitive indicator of diversification benefits nor do these benefits depend only on the correlation between asset returns. Using domestic, international, industryspecific, commodity and bond iShares, this study demonstrates that a return gap accounts for the effects of both correlations and standard deviation, and provides a perceptive measure of diversification benefits. It shows that relative rank of assets by diversification benefits is different when measured by correlation coefficient and by return gap. Therefore, investors seeking diversification opportunities could combine coefficient of correlation and return gap in practical asset allocation.
Non‐asbestos‐related malignant mesothelioma. A review

Malignant mesothelioma is an uncommon, but increasingly important, neoplasm. The existing English‐language medical literature concerning non‐asbestos‐related malignant mesotheliomas was reviewed for evidence of other agents associated with the induction of malignant mesothelioma. Both animal and human data were reviewed. In most reviews of malignant mesothelioma, there are a significant proportion of cases without documented asbestos exposure (range, 0% to 87%). Furthermore, there are several fairly well‐documented agents other than asbestos that induce malignant mesothelioma in animals, and strong evidence exists that such is the case in man. In reviews of malignant mesothelioma, the percentage of cases with asbestos exposure varies, but a significant number are apparently not asbestos related. It is believed that sufficient evidence exists to suggest that nonasbestos agents can induce malignant mesotheliomas in man, and additional epidemiologic studies in this area are needed.
Detection of a radio bridge in Abell 3667

We have detected a radio bridge of unpolarized synchrotron emission connecting the NW relic of the galaxy cluster Abell 3667 to its central regions. We used data at 2.3 GHz from the S-band Polarization All Sky Survey (S-PASS) and at 3.3 GHz from a follow up observation, both conducted with the Parkes Radio Telescope. This emission is further aligned with a diffuse X-ray tail, and represents the most compelling evidence for an association between intracluster medium turbulence and diffuse synchrotron emission. This is the first clear detection of a bridge associated both with an outlying cluster relic and X-ray diffuse emission. All the indicators point toward the synchrotron bridge being related to the post–shock turbulent wake trailing the shock front generated by a major merger in a massive cluster. Although predicted by simulations, this is the first time such emission is detected with high significance and clearly associated with the path of a confirmed shock. Although the origin of the relativistic electrons is still unknown, the turbulent re-acceleration model provides a natural explanation for the large-scale emission. The equipartition magnetic field intensity of the bridge is Beq = 2.2 ± 0.3 µG. We further detect diffuse emission coincident with the central regions of the cluster for the first time.
Effects of long-term contact lens wear on the corneal endothelium.

PURPOSE To analyze the long-term effects of soft and hard (PMMA) contact lenses (CL) on the human corneal endothelium. METHODS One hundred and one contact lens wearers with > or =10 years' wearing time and 50 healthy control subjects were examined with specular microscope. RESULTS The mean corneal endothelial cell densities of the CL wearers (2846 cells/mm2) and of the control eyes (2940 cells/mm2) differed by 94 cells/mm2 (p<0.05). The mean values for the coefficient of variation (CV) differed significantly (p<0.0001); for all CL wearers: mean CV=0.31, vs. for controls: 0.22. The mean endothelial cell density of the eyes exposed to CL wear for more than 25 years (30 eyes) was 2575 cells/mm2 (mean CV: 0.36). Rather low densities (<2000 cells/mm2) were observed in 16 eyes of the CL group (8%). Cell densities less than 2500 cells/mm2 were observed in a total of 41 eyes (20%) in the CL group, whereas in the control group (100 eyes) all of the subjects, except one, had cell densities of more than 2500 cells/mm2 in both eyes. CONCLUSION A subgroup of PMMA as well as soft contact lens wearers react not only with high pleomorphism and polymegethism but also with a decrease in endothelial cell density.
Risk and prognostic factors of transplantation‐associated thrombotic microangiopathy in allogeneic haematopoietic stem cell transplantation: a nested case control study

Transplantation‐associated thrombotic microangiopathy (TA‐TMA) is a significant complication of haematopoietic stem cell transplantation. However, it remains controversial which clinical or laboratory markers are of evident risk and prognostic value. From 2006 to 2013, a nested case control study was carried out in our centre to study the risk and prognostic factors of TA‐TMA. A total of 654 consecutive patients who underwent allogeneic haematopoietic stem cell transplantation were studied. Twenty‐six (4.0%) patients matched the established diagnostic criteria. Subjects with TA‐TMA had significantly higher 3‐year none relapse mortality compared with those without (65.4% vs 15.4%, P < 0.0001). Grades 2 to 4 aGVHD and cytomegalovirus viremia were independent risk factors, and serum LDH level >500U/L as well as hypertension were early signs of TA‐TMA occurrence. Liver dysfunction and significant gastric bleeding were independent risk factors for TA‐TMA related mortality. Subjects with either liver dysfunction or significant gastric bleeding had significantly higher 3 year TA‐TMA related mortality cumulative incidence than subjects without. These observations lead to the conclusion that allo‐HSCT recipients with grades 2 to 4 aGVHD or cytomegalovirus viremia should be monitored for TA‐TMA. Liver dysfunction and significant gastric bleeding are prognostic factors for TA‐TMA. Copyright © 2016 John Wiley & Sons, Ltd.
An Isokinetic Investigation of Contractile Mode's Effect on the Elbow Flexors

Healthy, sedentary, college-age subjects (n = 16) performed concentric or eccentric maximal unilateral isokinetic (1.08 rad·s−1) elbow flexor contractions (4 sets of 12 repetitions) to fatigue as physiological data were concurrently collected. Net caloric expenditure was determined using indirect calorimetry whereas the electromyogram examined root mean square (RMS) and mean power frequency (MPF) values for the biceps brachii, brachioradialis, and palmaris longus. Eccentric exercise resulted in significantly greater (p < 0.05) absolute (total work per kilocalorie) and relative (total work per kilocalorie per kilogram) exercise efficiency values. Concentric biceps brachii and brachioradialis RMS values were significantly (p < 0.05) greater than corresponding eccentric values, suggesting greater motor unit recruitment. Concentric MPF values, a measure of motor unit fatigue, showed significantly (p < 0.05) greater before and after decrements following exercise for the biceps brachii and brachioradialis. Greater exercise efficiency with less motor unit recruitment and fatigue results from eccentric exercise.