Miracle-dz/UniFAR-FTUs huggingface dataset:
Cross-Language Semantic Similarity of Arabic-English Short Phrases and Sentences

Measuring cross-language semantic similarity between short texts is a task that is challenging in terms of human understanding. This paper addresses this problem by carrying out a study of Arabic–English semantic similarity in short phrases and sentences. Human-rated benchmark dataset was carefully constructed for this research. Dictionary and machine translation techniques were employed to determine the relatedness between the cross-lingual texts from a monolingual perspective. Three algorithms were developed to rate the semantic similarity and these were applied to the human-rated benchmark. An averaged maximum-translation similarity algorithm was proposed using the term sets produced by the dictionary-based technique. Noun-verb and term vectors obtained by the Machine Translation (MT) technique were also suggested to compute the semantic similarity. The results were compared with the human ratings in our benchmark using Pearson correlation coefficient and these were triangulated with the best, worst and mean for all human participants. MT-based term vector semantic similarity algorithm obtained the highest correlation (r = 0.8657) followed by averaged maximum-translation similarity algorithm (r = 0.7206). Further statistical analysis showed no significant difference between both algorithms and the humans’ judgement.
Differential involvement of TRPV1 receptors at the central and peripheral nerves in CFA‐induced mechanical and thermal hyperalgesia

Transient receptor potential vanilloid 1 (TRPV1) antagonists are known to attenuate two typical symptoms of inflammatory hyperalgesia: thermal and mechanical. However, it is not clear whether the sites of participation of TRPV1 for each symptom are different. In this study, we clarified the difference between the site of TRPV1 involvement in both symptoms by analysing the anti‐hyperalgesic activity of two kinds of TRPV1 antagonists given locally (i.e. intraplantarly and intrathecally) in rats with CFA (complete Freund's adjuvant)‐induced inflammation. TRPV1 antagonists BCTC (N‐(4‐tertiarybutylphenyl)‐4‐(3‐cholorphyridin‐2‐yl) tetrahydropyrazine‐1 (2H)‐carbox‐amide, 1–300 μg) and SB‐366791 (N‐(3‐methoxyphenyl)‐4‐chlorocinnamide, 30–300 μg) administered intraplantarly in a dose‐dependent manner inhibited CFA‐induced thermal hyperalgesia. In addition, CFA‐induced thermal hyperalgesia was significantly reversed by intrathecal administration of 1–100μg of BCTC and SB‐366791. While intraplantar BCTC (1–300 μg) and SB‐366791 (30–300 μg) did not reverse CFA‐induced mechanical hyperalgesia, 1–100 μg of intrathecally administered BCTC and SB‐366791 dose‐dependently reduced mechanical hyperalgesia. Regression analysis showed that a correlation exists between the inhibitory effects on thermal hyperalgesia and mechanical hyperalgesia after intrathecal administration (correlation factor = 0.6521), but not after intraplantar administration (correlation factor = 0.0215). These data suggest that TRPV1 in the peripheral endings of the primary afferents plays a key role in thermal hyperalgesia, but it makes only a minor contribution in CFA‐induced mechanical hyperalgesia. Furthermore, it is suggested that the spinal TRPV1 is critical in the development of both types of hyperalgesia.
Effects of Water-Cement Ratios on the Compressive Strength and Workability of Concrete and Lateritic Concrete Mixes.

The variations of the compressive strengths of concrete and lateritic concrete mixes with watercement ratios of range 0.55 and 0.80, within 7 to 28 days after casting, were experimentally investigated in this research work. The experiment was carried out at the same ambient temperature and the compressive strengths of both concrete and lateritic concrete mixes were found to increase with age but decrease as the water-cement ratio increases. However, water-cement ratio above 0.65 was observed to have a very significant reduction effect on the compressive strength of the lateritic concrete mixes. This is in contrast to the performance of the concrete mixes which shows consistent decrease of compressive strength in water-cement ratio. Also, the degrees of workability of both concrete mixes were investigated using slump test.
The Impact of Managerial Leadership on Stress and Health Among Employees

The overall aim of this thesis was to explore the relationship between managerial leadership on the one hand and stress, health, and other health related outcomes among employees on the other. This was done in five studies, three using a cross-sectional and two a prospective design. In all studies the employees rated their managers with a self-administered questionnaire. The health outcomes were in four of the studies self-reported, but in the last study register-based diagnoses were used to determine incidence of ischemic heart disease. Logistic and Cox regression analyses were used to estimate the associations. In three of the five studies, the association between managerial leadership and the outcomes were adjusted for the dimensions in the Demand-control-support model. Other adjustments included staff category, labour market sector, job insecurity, marital status, satisfaction with life in general, and biological risk factors for cardiovascular disease. In the first study (I) Attentive managerial leadership was found to be significantly related to the employees perceived stress, age-adjusted self-rated health and sickness absence due to overstrain or fatigue in a multi-national company. The association remained significant after adjustment for the dimensions of the Demand-control-support model. In the second study (II) focussing hotel employees in Sweden, Poland, and Italy the factors Autocratic and Malevolent leadership (less common in Sweden than in the other two countries) aggregated to the organizational level were found to be related to poorer individual ratings of vitality. The relationships were significant also after adjustments for the dimensions of the Demand-control-support model aggregated to the organizational level. Self-centred leadership (which was as common in Sweden as in the other two countries) was related to poor employee mental health, vitality, and behavioural stress after these adjustments. The third study (III) showed significant associations in the expected directions between Inspirational leadership, Autocratic leadership, Integrity, and Team-integrating leadership on the one hand and self-reported sickness absence among employees on the other in SLOSH, a nationally representative sample of the Swedish working population. These associations were adjusted for the Demand-control-support model and self-reported general health (SRH). In the fourth (IV) prospective study significant associations were found between Dictatorial leadership and lack of Positive leadership on the one hand, and long-lasting stress, emotional exhaustion, deteriorated SRH, and the risk of leaving the workplace due to poor health or for unemployment on the other hand. In the fifth study (V) a dose-response relationship between positive aspects of managerial leadership and a lower incidence of hard end-point ischemic heart disease among employees was observed. This relationship was very little affected by adjustments for conventional risk factors for cardiovascular disease.
Tularemia as a cause of fever in a squirrel monkey.

CASE DESCRIPTION A 3-year-old female squirrel monkey (Saimiri sciureus sciureus) was examined because of sudden onset of lethargy and fever. CLINICAL FINDINGS On initial examination, the monkey was weak and febrile and had petechiae on both thoracic limbs. Following collection, blood samples were slow to clot. During the next week, the monkey developed anemia and thrombocytopenia; Francisella tularensis was isolated from blood samples. TREATMENT AND OUTCOME Treatment with gentamicin resulted in the monkey's gradual return to health, but inguinal lymphadenopathy developed after drug administration was discontinued. Francisella tularensis was isolated from a fine-needle aspirate of an enlarged lymph node. Treatment with streptomycin resulted in resolution of infection. By use of biochemical and molecular tests, the microbial isolate was characterized as F tularensis subsp holarctica. Results of a microagglutination assay confirmed that the monkey had developed serum antibodies against F tularensis. CLINICAL RELEVANCE With timely diagnosis, treatment of tularemia in the squirrel monkey was successful. Francisella tularensis is the cause of a highly infectious zoonotic disease, and infection with this microorganism is enzootic in wildlife throughout the Northern Hemisphere. Tularemia should be considered in the differential diagnosis of febrile disease in animals of any species. Even limited or indirect exposure of humans or other animals to outdoor environments in which reservoir hosts and arthropod vectors are present can lead to transmission of F tularensis. Francisella tularensis is a class A agent of bioterrorism, and all cases of tularemia (regardless of species) should be reported to public health officials.
Parent perspectives on home participation of high-functioning children with autism spectrum disorder compared with a matched group of children without autism spectrum disorder

Few studies have focused on home participation of high-functioning children with autism spectrum disorder. We employed a mixed-methods design to explore and compare parent perspectives on (1) participation of children with and without autism spectrum disorder in activities at home, (2) the environmental features and resources that affect these children’s home participation and (3) the strategies parents use to help their children participate at home. The Participation and Environment Measure for Children and Youth (PEM-CY) was used to gather online survey and qualitative data from parents of 99 high-functioning children with autism spectrum disorder and 241 children without autism spectrum disorder. Independent sample t-tests and χ2 tests were used to explore differences between groups, and Cohen’s d was calculated to examine effect sizes. Differences were obtained on all Participation and Environment Measure for Children and Youth dimensions but particularly when comparing parents’ satisfaction and perceived environmental barriers to their children’s participation. The qualitative analyses revealed that parents in both groups used similar strategies to facilitate their children’s participation at home, although parents of children with autism spectrum disorder made use of more distinct modifications. Our results highlight the importance of environmental aspects and point to how practitioners can support families in their efforts to promote their child’s participation at home.
Insulin Secretion During Development: Response of Isolated Pancreatic Islets of Fetal, Newborn and Adult Rats to Theophylline and Arginine*

CII/mce, R.E. , R.M. EI/is: Proinsulin: Single-chain precursor of insulin. Arch.int.Med 123: 229 (1969) J)Qvoren, P.R. : The isolation of insulin from a single cat pancreas. Biochim.biophys. Acta 63: 150 (1962) Espinosa de los Monteros, A. , S. G. Driscol/, J. Steinke: Insulin release from isolated human fetal pancreatic islets. Science 168: Illl (1970) RastoKi, G.K. , J. LeTarte, T.R. Froser: Proinsulin content of pancreas in human fetuses of healthy mothers. Lancet I: 7 (1970) Steiner, D.F. , P.E. Oyer: The biosynthesis of insulin and a probable precursor of insulin by a human islet ce11 adenoma. Proc.Nat.Acad.Sci. USA 57: 473 (1967) synthesis of insulin and does not represent a major storage form of the hormone.
Identification and extraction of 'domain independent' components in large programs

The problem of the identification and extraction of domain independent components from a large working program lacking complete documentation is addressed. A modified version of Weiser's slice (Direct Slice) is defined, which makes it possible to individuate and extract particular kinds of code segments distributed among many of the modules composing the structure of the working program. Program components may be individuated and aggregated coherently according to the principles of information hiding. The techniques described are characterized by a certain simplicity and can thus be automized. The study is based on the results of an experimental project performed on applicative programs used in the banking sector, characterized by a high grade of difficulty as regards maintenance. <<ETX>>
Monokine induced by interferon gamma (IFNgamma) (CXCL9) and IFNgamma inducible T-cell alpha-chemoattractant (CXCL11) involvement in Graves' disease and ophthalmopathy: modulation by peroxisome proliferator-activated receptor-gamma agonists.

CONTEXT CXC alpha-chemokine CXCL10/IP-10 plays an important role in the initial phases of Graves' ophthalmopathy (GO). Human thyrocytes, orbital fibroblasts, and preadipocytes are stimulated to produce CXCL10 when treated with interferon gamma (IFNgamma) and TNFalpha. Peroxisome proliferator-activated receptor-gamma (PPARgamma) activation plays an inhibitory role in this process. OBJECTIVE Until now, no data are present in literature about the involvement of CXCL9 and CXCL11 in Graves' disease and GO, or of PPARgamma activators' effect on these chemokines. METHODS It has been studied how IFNgamma and TNFalpha stimulation and PPARgamma activation affect CXCL9 and CXCL11 secretion in primary cultures of thyrocytes, orbital fibroblasts, and preadipocytes. RESULTS In primary cultures of thyrocytes, retrobulbar fibroblasts, and retrobulbar preadipocytes obtained from GO patients, CXCL9 and CXCL11 production was absent under basal conditions; CXCL9 and CXCL11 secretion was not induced by TNFalpha alone, whereas it was dose dependently stimulated treating cells with IFNgamma. The treatment with TNFalpha plus IFNgamma has a synergistic effect on CXCL9 and CXCL11 release. Treating all cell types with the PPARgamma agonist, rosiglitazone, or pioglitazone, the IFNgamma plus TNFalpha-induced CXCL9 and CXCL11 release was dose dependently (0.1-20 microm) suppressed. CONCLUSIONS We conclude that thyrocytes and retrobulbar cell types from patients with Graves' disease and ophthalmopathy participate in the self-perpetuation of inflammation, releasing CXCL9 and CXCL11 chemokines when stimulated with cytokines. PPARgamma activation plays an inhibitory role in this process. The huge response of CXCL9 to the IFNgamma plus TNFalpha-stimulation suggests its leading role among CXC chemokines.
RCS computations of targets with plasmonic coatings

RCS issues lead to problems of hundreds of thousands of unknowns as soon as the target gets greater than the wavelength. For computational limiting reasons, details of the coating cannot thus be meshed, even if they play a key role like in metamaterial design. Equivalent boundary conditions or effective medium approximation are then necessary. In this paper we consider spheres with plasmonic coatings. Exact and approximated RCS computations are compared over a broad range of RF frequencies.
Fast Tensor Principal Component Analysis via Proximal Alternating Direction Method with Vectorized Technique

This paper studies the problem of tensor principal component analysis (PCA). Usually the tensor PCA is viewed as a low-rank matrix completion problem via matrix factorization technique, and nuclear norm is used as a convex approximation of the rank operator under mild condition. However, most nuclear norm minimization approaches are based on SVD operations. Given a matrix , the time complexity of SVD operation is O(mn2), which brings prohibitive computational complexity in large-scale problems. In this paper, an efficient and scalable algorithm for tensor principal component analysis is proposed which is called Linearized Alternating Direction Method with Vectorized technique for Tensor Principal Component Analysis (LADMVTPCA). Different from traditional matrix factorization methods, LADMVTPCA utilizes the vectorized technique to formulate the tensor as an outer product of vectors, which greatly improves the computational efficacy compared to matrix factorization method. In the experiment part, synthetic tensor data with different orders are used to empirically evaluate the proposed algorithm LADMVTPCA. Results have shown that LADMVTPCA outperforms matrix factorization based method.
Laboratory Evaluation of Carbon Monoxide Exposure in CO2 Arc Welding

During metal active gas (MAG) welding process, several chemical and physical emissions such as welding fumes, ozone, nitrogen compounds, and ultraviolet radiation are generated. Carbon monoxide (CO) produced from the shield gas by the action of heat upon the welding flux and slag is one of the hazardous contaminants in CO 2 arc welding (also known as MAG welding). CO is a lethal poison and can overcome the exposed person without warning because it is colorless, tasteless, odorless, and non-irritating. Although CO poisoning of a welder is not as serious as pneumoconiosis due to welding fumes, it is still a common occurrence in Japanese production weld shops. It is generally known that contaminant concentrations in stationary measurement tend to be appreciably less than those in the breathing zone. This is especially remarkable in the case of welding where the workers are close to the arc points (contaminant sources). Therefore, the exposure of a welder is better evaluated by a personal sampling method rather than by the area sampling method which is prescribed as “A-sampling” in the Japanese Working Environment Measurement Law. According to former studies, lower concentrations of welding fumes, ozone, nitric oxide and nitric dioxide inside the welding face shield have been found . Alpaugh et al. suggested that the partially confined space between the welding face shield and a welder’s head is a reservoir of relatively pure air, and continues to be an effective barrier to airborne contaminants during arc is struck. Hence, exposure will be overestimated if the sampler is mounted on the lapel or on the shoulder of a welder rather than in the actual breathing zone, inside the face shield. Since little data have been published regarding the true CO exposure level during CO 2 arc welding, the author attempted to compare CO concentrations inside and outside the welding face shield and to determine the extent of CO reduction afforded by the shield.
Targeting the angiopoietin/Tie2 pathway: cutting tumor vessels with a double-edged sword?

Angiogenesis inhibitors have now been tested for more than a decade. Most approaches have focused on blockade of the vascular endothelial growth factor (VEGF) pathway, and such agents are part of standard therapies for several malignancies including renal cell, colorectal, and non–small-cell lung cancers. However, in most cases, these drugs provide modest or no benefit, and therapeutic resistance almost inevitably occurs. It seems clear that our therapeutic approaches have not kept pace with our knowledge of the diverse pathways known to play a role in tumor vasculature. In Journal of Clinical Oncology (JCO), Karlan et al report encouraging results of a randomized phase II study of AMG 386, a peptide targeting the angiopoietin (Ang)/Tie2 pathway. This pathway is a challenging target for several reasons, particularly because it may be proor antitumorigenic, depending on the context, and because the drug simultaneously targets both the Tie2 ligand (Ang1) and its naturally occurring antagonist, Ang2 (Figs 1A to 1D). It also seems to be a critical pathway for tumor angiogenesis. In this Understanding the Pathway article, the biology of the Ang/Tie2 pathway and rationale for its targeting will be reviewed.
Regression models for categorical dependent variables using Stata, 2nd Edition

Preface PART I GENERAL INFORMATION Introduction What is this book about? Which models are considered? Whom is this book for? How is the book organized? What software do you need? Where can I learn more about the models? Introduction to Stata The Stata interface Abbreviations How to get help The working directory Stata file types Saving output to log files Using and saving datasets Size limitations on datasets Do-files Using Stata for serious data analysis Syntax of Stata commands Managing data Creating new variables Labeling variables and values Global and local macros Graphics A brief tutorial Estimation, Testing, Fit, and Interpretation Estimation Postestimation analysis Testing estat command Measures of fit Interpretation Confidence intervals for prediction Next steps PART II MODELS FOR SPECIFIC KINDS OF OUTCOMES Models for Binary Outcomes The statistical model Estimation using logit and probit Hypothesis testing with test and lrtest Residuals and influence using predict Measuring fit Interpretation using predicted values Interpretation using odds ratios with listcoef Other commands for binary outcomes Models for Ordinal Outcomes The statistical model Estimation using ologit and oprobit Hypothesis testing with test and lrtest Scalar measures of fit using fitstat Converting to a different parameterization The parallel regression assumption Residuals and outliers using predict Interpretation Less common models for ordinal outcomes Models for Nominal Outcomes with Case-Specific Data The multinomial logit model Estimation using mlogit Hypothesis testing of coefficients Independence of irrelevant alternatives Measures of fit Interpretation Multinomial probit model with IIA Stereotype logistic regression Models for Nominal Outcomes with Alternative-Specific Data Alternative-specific data organization The conditional logit model Alternative-specific multinomial probit The sturctural covariance matrix Rank-ordered logistic regression Conclusions Models for Count Outcomes The Poisson distribution The Poisson regression model The negative binomial regression model Models for truncated counts The hurdle regression model Zero-inflated count models Comparisons among count models Using countfit to compare count models More Topics Ordinal and nominal independent variables Interactions Nonlinear models Using praccum and forvalues to plot predictions Extending SPost to other estimation commands Using Stata more efficiently Conclusions Appendix A Syntax for SPost Commands Appendix B Description of Datasets References Author Index Subject Index
Coupling of DNA Synthesis and Histone Synthesis in S Phase Independent of Cyclin/cdk2 Activity

ABSTRACT DNA and histone synthesis are both triggered at the beginning of S phase by cyclin/cdk2 activity. Previous studies showed that inhibition of DNA synthesis with hydroxyurea or cytosine arabinoside (AraC) triggers a concerted repression of histone synthesis, indicating that sustained histone synthesis depends on continued DNA synthesis. Here we show that ectopic expression of HIRA, the likely human ortholog of two cell cycle-regulated repressors of histone gene transcription in yeast (Hir1p and Hir2p), represses transcription of histones and that this, in turn, triggers a concerted block of DNA synthesis. Thus, in mammalian cells sustained DNA synthesis and histone synthesis are mutually dependent on each other during S phase. Although cyclin/cdk2 activity drives activation of both DNA and histone synthesis at the G1/S transition of cycling cells, concerted repression of DNA or histone synthesis in response to inhibition of either one of these is not accompanied by prolonged inhibition of cyclin A/cdk2 or E/cdk2 activity. Therefore, during S phase coupling of DNA and histone synthesis occurs, at least in part, through a mechanism that is independent of cyclin/cdk2 activity. Coupling of DNA and histone synthesis in S phase presumably contributes to the prompt and orderly assembly of newly replicated DNA into chromatin.