Miracle-dz/UniFAR-FTUs huggingface dataset:
Revisiting the paleomagnetism of the Neoarchean Uauá mafic dyke swarm, Brazil: Implications for Archean supercratons

The original connections of Archean cratons are becoming traceable due to an increasing amount of paleomagnetic data and refined magmatic barcodes. The Uauá block of the northern São Francisco craton may represent a fragment of a major Archean craton. Here, we report new paleomagnetic data from the 2.62 Ga Uauá tholeiitic mafic dyke swarm of the Uauá block in the northern São Francisco craton, Eastern Brazil. Our paleomagnetic results confirm the earlier results for these units, but our interpretation differs. We suggest that the obtained characteristic remanent magnetization for the 2.62 Ga swarm is of primary origin, supported by a provisionally-positive baked contact test. The corresponding paleomagnetic pole (25.2°N, 330.5°E, A95 = 8.1°, N = 20) takes the present northern part of the São Francisco craton to moderate latitudes. Based on the comparison of the paleolatitudes of cratons with high-quality paleomagnetic data and magmatic barcodes, we suggest that the northern part of the São Francisco craton could have been part of the proposed Supervaalbara supercraton during the Archean. Supervaalbara is proposed as including (but not limited to) the part of the São Francisco craton as well as the Superior, Wyoming, Kola + Karelia, Zimbabwe, Kaapvaal, Tanzania, Yilgarn, and Pilbara cratons.
The prevalence and correlates of binge eating disorder in the WHO World Mental Health Surveys

Background—Little population-based data exist outside the United States on the epidemiology of binge eating disorder (BED). Cross-national data on BED are presented and compared to bulimia nervosa (BN) based on the WHO World Mental Health Surveys. Methods—Community surveys with 24,124 respondents (ages 18+) across 14 mostly uppermiddle and high income countries assessed lifetime and 12-month DSM-IV mental disorders with the WHO Composite International Diagnostic Interview. Physical disorders were assessed with a chronic conditions checklist. Results—Country-specific lifetime prevalence estimates are consistently (median; inter-quartile range) higher for BED (1.4%;0.8–1.9%) than BN (0.8%;0.4–1.0%). Median age-of-onset is in the late teens to early 20s for both disorders but slightly younger for BN. Persistence is slightly higher for BN (6.5 years; 2.2–15.4) than BED (4.3 years; 1.0–11.7). Lifetime risk of both disorders is elevated for women and recent cohorts. Retrospective reports suggest that comorbid anxiety, mood, and disruptive behavior disorders predict subsequent onset of BN somewhat more strongly than BED and that BN predicts subsequent comorbid psychiatric disorders somewhat more strongly than does BED. Significant comorbidities with physical conditions are due almost entirely to BN and BED predicting subsequent onset of these conditions, again with BN somewhat stronger than BED. Role impairments are similar for BN and BED. Fewer than half of lifetime BN or BED cases receive treatment. Conclusions—BED represents a public health problem at least equal to BN. Low treatment rates highlight the clinical importance of questioning patients about eating problems even when not included among presenting complaints.
Growth , blood metabolites and hormones in calves fe d diets with different amounts of energy and protein during the pre-or post-weaning periods

We investigated the effects of diets differing in e nergy and protein concentrations given during preand post-weaning on hormone and metabolite levels in as sociation to parameters of growth. Sixteen Aberdeen Angus calves four-day-old were allocated i n individual pens during 105 days in a randomized complete design. Animals consumed ad libitum various diets differing in proportion of energy and protein (A: 80% of concentrate, 20% alfalfa hay; B: 60% concentrate, 40% of alfalfa hay; C: 40% concentrate, 60% alfalfa hay, and D: 20% concentrat e, 80% alfalfa hay). Also, calves consumed milk substitute up to 60-day-old day. Serum growth hormo ne and cortisol levels were not altered with diet changes (P > 0.05) neither during the prenor the post-weaning periods. Plasma insulin concentration average daily intake, glucose and thyroid hormone l evels, and concentrations of ammonia nitrogen and propionic acid were greater (P < 0.01) for diets ha ving higher than lower energy and protein levels during the post-weaning but not during the pre-wean ing period. These results suggest inclusion of higher amounts of concentrate in the diet of weaned calves.
Per-capita income , consumption patterns and CO 2 emissions Preliminary working paper

This paper investigates the importance of per-capita income and the sectoral composition of consumption as determinants for the level and evolution of carbon dioxide (CO2) emissions across countries. It is based on the model and estimation strategy in Caron, Fally and Markusen (2012) which allows the identification of the income elasticity of consumption by controlling for cross-country price differences which are inferred from bilateral trade flows. At the sector-level, we find a statistically significant negative correlation between income elasticity and the total CO2 intensity of production. At the country-level, the data exhibits an inverted-U relationship between per-capita income and the average CO2 content of both consumption and production. The relationship holds when evaluated using average production intensities and is thus partially generated by differences in consumption patterns. In turn, we find these differences to be explained by per-capita income levels. Importantly, the link is much weaker for the total CO2 content of consumption than for the direct content, as total energy demand is more income-elastic than direct household consumption. This finding implies a modest scope for per-capita income growth to reduce aggregate CO2 emission intensity purely through its impact on consumption shares. We estimate the elasticity of the average total CO2 content of worldwide consumption (which equals that of production) to per-capita income to be only -0.06, with, however, larger reductions in rich countries.
ON SEMI-INVARIANT ξ⊥-SUBMANIFOLDS OF LORENTZIAN PARA-SASAKIAN MANIFOLDS

MOBIN AHMAD∗ Abstract. In the present paper, we study semi-invariant ξ⊥-submanifolds of Lorentzian para-Sasakian manifolds. We discuss the integrability conditions of the distributions D and D⊥ on semi-invariant ξ⊥-submanifolds of Lorentzian para-Sasakian manifolds. We also obtain some characterizations for the totally umbilical semi-invariant ξ⊥-submanifolds of Lorentzian para-Sasakian manifolds.
Simcoe County District School Board, Ontario

This study focuses on four key issues: the perception of the role played by principals in Ontario in the administration and supervision of special education programs and services; the extent to which the construct of the principal as the instructional leader accurately depicts the role of the principal in schools with high concentrations of students with special needs; the knowledge and skills needed by principals for them to assume responsibility for the administration and supervision of special education programs and services in school contexts of diversity and difference; and the [re]structuring of leadership preparation programs to bridge the gap between current knowledge and leadership/classroom practice.
Chronic vs Transient Poverty : the Case of Rural China

The poverty decomposition framework of Rodgers and Rodgers (1993) is found to violate the focus axiom of Sen (1976). An alternative is proposed in this paper and then applied to a panel data from rural China. Our empirical results indicate that chronic poverty dominates total poverty in rural China. Further, larger households are more likely to be poor. Those mainly engaged in farming tend to suffer more transient poverty. Finally, physical, financial, political and human capital all contribute to poverty reduction. It is particularly recommended that policy makers in China shall focus on chronic poverty rather than transient poverty.
CUSTOMIZATION OF ELECTROSPINNING FOR TISSUE ENGINEERING UDC 678 . 3 : 66 . 095 . 26

This paper deals with two electrospinning technologies: the melt electrospinning with a customized jet head, adapted from the fused deposition modeling (FDM) 3D printer, in comparison with the standard solution electrospinning, aiming at fabrication of tissue engineering scaffolds. The resulting fibers are compared. The influence of the collector properties on those of the fabricated scaffold is investigated. The resulting electrospun fibers exhibit different characteristics such as morphology and thickness, depending on the technology. The micro-fibers are produced by the melt electrospinning with an inbuilt 3D printer jet head, whereas the solution electrospinning has produced nanoand micro-fibers. The scaffolds fabricated on the rotating drum collector exhibit a more ordered structure as well as thinner fibers than those produced on the stationary plate collector. Further investigations should aim at fabrication of porous hollow fibers and tissue engineering scaffolds with controlled porosity and properties.
Title Visualization of Green ' s function anomalies for megathrustsource in Nankai Trough by reciprocity method

We used simulation by the reciprocity method to visualize the distribution of Green’s function amplitudes in the source of a megathrust earthquake in the Nankai Trough and considered the effects of various areas (asperities or strong motion generation areas) on the simulated long-period ground motions at Konohana in the Osaka basin. We employed a fault source model proposed for an anticipated M9-class event in the Nankai Trough and the 3D Japan Intergrated Velocity Structure Model developed for simulations of long-period ground motions in Japan. Green’s functions were calculated for about 1400 subsources by combining the finite-difference method and the reciprocity approach. Depths, strikes, and dips of subsources were adjusted to the shape of the upper boundary of the Philippine Sea plate. Ground motions with periods of 4–20 s were considered. The simulated distribution of peak amplitudes of Green’s functions identified two strongly anomalous areas: (1) a large along-strike elongated area just south of the Kii Peninsula and (2) a parallel area closer to the trench. The elongation of the anomalies corresponded well with depth isolines at the top of the Philippine Sea plate. Postulating that plate shape influences simulated ground motions, we investigated the effect on Green’s function amplitudes of phenomena related to plate shape: radiation pattern; variations of medium properties (e.g., velocity and density) at subsource depths; depth, strike, and dip; and the effect of soft sediments. We suggest that the cumulative effect on Green’s function amplitudes of subsource radiation patterns, medium properties at subsource depth, reflection from crustal interfaces, and passage through soft sedimentary layers plays a critical role in the formation of amplitude anomalies. Analysis of waveforms and the time delay of peak amplitude demonstrate that large-amplitude waves of Green’s functions in shallow parts of the plate boundary are composed mostly of surface waves.
LAURI NISKANEN MULTI-LABEL SPEAKER RECOGNITION USING RECURRENT NEURAL NETWORKS

LAURI NISKANEN: Multi-Label Speaker Recognition using Recurrent Neural Networks Tampere University of Technology Master of Science thesis, 43 pages November 2018 Master’s Degree Programme in Information Technology Major: Pervasive Systems Examiners: Professor Tuomas Virtanen and Professor Hannu-Matti Järvinen
Hammock positon and nestng : comparison of ph siocogicac and behaviorac efects in preterm infants

Objective: To compare the effects of the use of hammocks versus nesting in preterm infants, after diaper changing. Methods: quasi-experimental study, a cross-over trial with 30 preterm newborns in an intermediate care nursery (ICN) in a public hospital in Brasilia-DF, conducted from November 2011 to March 2012. The effects of the two interventions (nesting and hammock) after diaper changing were assessed. Student’s t test with a confidence level of 95% (p <0.05) was used in data analysis. Results: In hammock position the preterm infants were found to be less stressed (p = 0.002), had fewer defining characteristics indicating nursing diagnosis “Disorganized Infant Behavior” (p = 0.05) and remained in a more suitable position for receiving intensive care compared to nesting (p = 0.04). Conclusion: Preterm infants in hammock position, compared to nesting, were less stressed, with a more organized behavior and in a better position for receiving intensive care.
Effects of water stress and nitrogen supply on leaf gas exchange and fluorescence parameters of Sophora davidii seedlings

Two-month-old seedlings of Sophora davidii were subjected to a randomized complete block design with three water (80, 40, and 20 % of water field capacity, i.e. FC80, FC40, and FC20) and three N supply [N0: 0, Nl: 92 and Nh: 184 mg(N) kg(soil)] regimes. Water stress produced decreased leaf area (LA) and photosynthetic pigment contents, inhibited photosynthetic efficiency, and induced photodamage in photosystem 2 (PS2), but increased specific leaf area (SLA). The decreased net photosynthetic rate (PN) under medium water stress (FC40) compared to control (FC80) might result from stomatal limitations, but the decreased PN under severe water deficit (FC20) might be attributed to non-stomatal limitations. On the other hand, N supply could improve photosynthetic capacity by increasing LA and photosynthetic pigment contents, and enhancing photosynthetic efficiency under water deficit. Moreover, N supply did a little in alleviating photodamages to PS2 caused by water stress. Hence water stress was the primary limitation in photosynthetic processes of S. davidii seedlings, while the photosynthetic characters of seedlings exhibited positive responses to N supply. Appropriate N supply is recommended to improve photosynthetic efficiency and alleviate photodamage under water stress. Additional key words: adaptation; chlorophyll fluorescence; intercellular CO2 concentration; leaf area; net photosynthetic rate; respiration rate; specific leaf area; stomatal conductance; water use efficiency.
Adult Education SELF-REGULATION IN HIGHER EDUCATION : STUDENTS ’ MOTIVATIONAL , REGULATIONAL AND LEARNING STRATEGIES , AND THEIR RELATIONSHIPS TO STUDY SUCCESS PÄIVI

This study investigates how in the self-regulation of learning (SRL; Pintrich 2000; Zimmerman, 2000), the motivational and affective factors are related to regulation strategies of behaviour and context, and learning strategies and identifies different profiles in SRL. The study also aims to explore which factors of SRL are related to study success and study progress during master degree studies. The data consist of undergraduate students’ (N = 1248) responses to IQ Learn self-report questionnaires, and of data (n = 229) retrieved from the university’s study register. The results revealed that the sub-processes of SRL: motivational and affective components, regulation strategies and learning strategies are systematically related with each other. In addition, motivational and affective factors, especially Intrinsic motivation predicted the use of strategies regulating behaviour and context and the use of learning strategies. Study success correlated slightly positively with accumulation of credits indicating that students with better grades proceed efficiently in their studies. Yet, accumulation of credits was evidenced to relate slightly and negatively with expectancy components of SRL and the use of deep learning strategies. Finally, three student profiles in SRL were encountered: (1) Aiming high with insufficient SRL, (2) Excellent in SRL, and (3) Distressed performers. Educational implications and the needs for future research are discussed.
Diversity and Biomass of Understory Plants in Larix gmelinii Forest under Different Reconstruction Methods

Article history Received: 1 April 2019 Accepted: 17 April 2019 Published Online: 30 April 2019 The effects of different management measures on the undergrowth diversity of Larix gmelinii forests were determined. The undergrowth vegetation of Xing'an Larch forest under seven different transformation methods was investigated in the Chaocha Forest Farm of the Genhe Forestry Bureau in the northern Daxinganling Mountains. Community composition, structural characteristics, species diversity and biomass of seven different retrofitting methods and one control plot. The results showed that the species composition of Larix gmeliniii under 7 different transformation methods included 34 species of 30 genera and 21 families of shrubs, including 7 species, 7 genera and 7 species of shrub layer, and 20 species, 24 genera and 24 species of common species in the herb layer. The species with the largest proportion in the layer is bilberry, followed by Xing'an rhododendron, and the dominant species of herbaceous layer is quite different. In terms of diversity index, the diversity index of Xing'an larch forest under local tending artificial promotion natural regeneration and transformation measures was low (P<0.05); the study showed that the best tending thinning intensity was between 30% and 40%, different. The impact of the transformation method on the structure and diversity of understory vegetation in Larix gmelinii forest is not only related to the transformation, but also depends on the transformation measures taken.
Instructions for use Title Safety and effectiveness of subcutaneous tocilizumab in patients with rheumatoid arthritis in a real-world clinicalsetting

Objectives: The objective of this study is to evaluate the safety and effectiveness of subcutaneous tocilizumab (TCZ-SC) in a real-world clinical setting in Japan. Methods: This single arm, 26-week prospective observational study enrolled patients with RA who were either TCZ naïve or switched from TCZ-IV to TCZ-SC (TCZ-IV-SC group) (UMIN Clinical Trials Registry UMIN000011102). All patients received TCZ-SC 162mg every 2 weeks and data were collected until week 26 or discontinuation. Results: Overall 784 (78.1%) were TCZ naïve and 219 (21.8%) were in the TCZ-IV-SC group. 70.9% received disease-modifying antirheumatic drugs at baseline. Adverse events (AEs) and serious AEs occurred in 28.2% and 4.9% of patients, respectively (TCZ-naïve: 29.5% and 5.2%; TCZ-IV-SC: 23.2% and 4.1%). Infections and infestations were the most common AEs (7.4%) and serious AEs (1.7%). Two TCZnaïve patients died. TCZ-naïve patients had an improvement in median Clinical Disease Activity Index (CDAI) score and mean Disease Activity Score in 28 joints as measured by erythrocyte sedimentation rate (DAS28-ESR) from baseline to week 26. The TCZ-IV-SC group had similar median CDAI scores and mean DAS28-ESR over 26 weeks. Conclusions: There were no unexpected safety signals with TCZ-SC. TCZ-SC was effective in reducing disease activity in TCZ-naïve patients and maintaining remission in TCZ-IV-SC patients. ARTICLE HISTORY Received 9 June 2017 Accepted 3 December 2017
Aerothermodynamics of Spiked Bodies : Part II

The two main design objectives namely, reducing the drag and reducing the aeroheating can be satisfied using the spikes and aerodisks. This field of aerodynamics has gained much interest over the years and is still attracting the researchers' interest. The target of this study is to illustrate these contributions. In the first part of this study, the aerothermodynamic characteristics of spiked bodies are discussed and the previous studies are illustrated. In this part, the recent contributions of the authors are presented and a number of future research areas are proposed.
A Mouse Model for Osseous

GNAS/Gnas encodes Gsa that is mainly biallelically expressed but shows imprinted expression in some tissues. In Albright Hereditary Osteodystrophy (AHO) heterozygous loss of function mutations of GNAS can result in ectopic ossification that tends to be superficial and attributable to haploinsufficiency of biallelically expressed Gsa. Oed-Sml is a point missense mutation in exon 6 of the orthologous mouse locus Gnas. We report here both the late onset ossification and occurrence of benign cutaneous fibroepithelial polyps in Oed-Sml. These phenotypes are seen on both maternal and paternal inheritance of the mutant allele and are therefore due to an effect on biallelically expressed Gsa. The ossification is confined to subcutaneous tissues and so resembles the ossification observed with AHO. Our mouse model is the first with both subcutaneous ossification and fibroepithelial polyps related to Gsa deficiency. It is also the first mouse model described with a clinically relevant phenotype associated with a point mutation in Gsa and may be useful in investigations of the mechanisms of heterotopic bone formation. Together with earlier results, our findings indicate that Gsa signalling pathways play a vital role in repressing ectopic bone formation. Citation: Cheeseman MT, Vowell K, Hough TA, Jones L, Pathak P, et al. (2012) A Mouse Model for Osseous Heteroplasia. PLoS ONE 7(12): e51835. doi:10.1371/ journal.pone. 0051835 Editor: Kathleen Freson, University of Leuven, Belgium Received May 21, 2012; Accepted November 7, 2012; Published December 19, 2012 Copyright: 2012 Cheeseman et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Funding: All co-authors with the exception of MVM are core funded by the Medical Research Council. (www.mrc.ac.uk/). No additional external funding received for this study. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing Interests: Co-author MVW is now the director of a commercial company (Pathology Diagnostics Ltd). There are no relevant conflicts relating to employment, consultancy, patents, products in development or marketed products etc. with respect to the work on this animal model, as this is not the subject of the business. MVM is purely an academic collaborator who made her contributions to the phenotying of this mouse model before the advent of her company. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials. * E-mail: m.cheeseman@har.mrc. ac.uk
IFN-g – related mRNA profile predicts clinical response to PD-1 blockade

Programmed death-1–directed (PD-1–directed) immune checkpoint blockade results in durable antitumor activity in many advanced malignancies. Recent studies suggest that IFN-g is a critical driver of programmed death ligand-1 (PD-L1) expression in cancer and host cells, and baseline intratumoral T cell infiltration may improve response likelihood to anti–PD-1 therapies, including pembrolizumab. However, whether quantifying T cell– inflamed microenvironment is a useful pan-tumor determinant of PD-1–directed therapy response has not been rigorously evaluated. Here, we analyzed gene expression profiles (GEPs) using RNA from baseline tumor samples of pembrolizumab-treated patients. We identified immune-related signatures correlating with clinical benefit using a learn-andconfirm paradigm based on data from different clinical studies of pembrolizumab, starting with a small pilot of 19 melanoma patients and eventually defining a pan-tumor T cell– inflamed GEP in 220 patients with 9 cancers. Predictive value was independently confirmed and compared with that of PD-L1 immunohistochemistry in 96 patients with head and neck squamous cell carcinoma. The T cell–inflamed GEP contained IFN-g–responsive genes related to antigen presentation, chemokine expression, cytotoxic activity, and adaptive immune resistance, and these features were necessary, but not always sufficient, for clinical benefit. The T cell–inflamed GEP has been developed into a clinical-grade assay that is currently being evaluated in ongoing pembrolizumab trials. Research Article Immunology Oncology