Miracle-dz/UniFAR-FTUs huggingface dataset:
Outcomes of Parent-Child Interaction Therapy: Mothers' Reports of Maintenance Three to Six Years After Treatment

Examined the long-term maintenance of changes following parent-child interaction therapy (PCIT) for young children with oppositional defiant disorder (ODD) and associated behavior disorders. Three to 6 years after treatment, 29 of 50 treatment completers were located for this study. The mothers of 23 children between the ages of 6 and 12 participated in telephone and mail follow-up assessments. Results indicated that the significant changes that mothers reported in their children's behavior and their own locus of control at the end of treatment were maintained at long-term follow- up. Child behavior reported at the posttreatment assessment and length of time since treatment were strong predictors of long-term outcome. Mothers'reports of disruptive behavior decreased with time since treatment. The results of this study support the long-term effectiveness of PCIT.
Supply chain natural resource scarcity strategies and their implications for ogranisational performance.:an empirical study of manufacturing companies.

Concerns about natural resource scarcity are growing as some of these resources are critical for the successful functioning of firms. Research into the appropriate strategies for minimising dependencies caused by the scarcity of natural resources is still insufficient in the field of supply chain management. Whilst there is a growing recognition of the need to handle the issue of natural resource scarcity, there is limited empirical work on investigating what supply chain strategies should be utilised. This research provides insights from manufacturing companies and explores the conditions under which a specific natural resource will lead to buffering and/or bridging strategies and the implications for organisational performance. The research attempts to contribute to theory development by developing a Resource Dependence Theory based framework. The framework identifies the contingency factors that determine companies’ dependence that leads to specific supply chain strategies. This study contributes further into the identification of the impacts of these strategies on organisational performance. The proposed conceptual framework is validated through the means of exploratory research. The empirical research included the collection of qualitative data from thirteen companies that use different natural resources. In order to manage and analyse the 31 semi-structured interviews content analysis was conducted using the qualitative analysis software NVivo. After the qualitative first stage, quantitative research followed to validate the findings. Responses from 183 logistics, purchasing and supply chain managers were collected and analysed by using the partial least squares (PLS) method to verify the relationships between the constructs in the framework. The study reveals that there are three main contingent factors, namely; the importance of the scarce natural resource (e.g. the price of the natural resources), the supplier substitutability of the scarce natural resource (e.g. number of suppliers) and the discretion over the scarce natural resource (e.g. legislation and geopolitical risk). This is leading companies to natural resource dependencies thus to specific supply chain NRS strategies (i.e. buffering strategies and bridging strategies). The research has shown that the two strategies can improve both resource efficiency and a company’s competitive advantage.
Successfully Communicating a Cocreated Innovation

Despite the growing popularity of cocreation approaches to innovation, the bottom-line results of these efforts continue to frustrate many firms. Marketing communications are one important tool in stimulating consumer adoption, yet marketers to date have not taken advantage of a unique phenomenon associated with many cocreated innovations: the presence of a genesis story in the words of the creator, which can be combined in different ways with traditional marketing messaging. Using mixed methods, the authors demonstrate a crossover effect in which a “mismatch” of the fundamental motivations behind authentic creation narratives and traditional persuasive messages enhances adoption of the cocreated innovation. This effect is mediated by potential adopters’ self-referencing of their own stories about similar experiences or consumption episodes. Furthermore, the effect of a motivation mismatch strategy is attenuated for expert consumers. Finally, this motivation mismatch strategy triggers “takeoff” of cocreated innovations. This research offers substantial implications for research on cocreated innovation, narrative persuasion, and firm-generated and user-generated communication. It provides managers specific guidance on enhancing the success of cocreation programs through an integrated communications strategy.
Differences in the acid production and phosphorus metabolism of oxytetracylcine sensitive and resistant organisms.

Various investigators have suggested that antibiotic resistant cultures might be used in the manufacture of cultured dairy products from milk containing traces of antibiotics following antibiotic therapy (Hargrove et al., 1950; Katznelson and Hood, 1949; and Krienke, 1950). Angelotti (1955) developed four oxytetracycline resistant strains of Streptococcus lactis and noticed that these cultures grew normally, but could not produce desirable amounts of acid. He observed that the resistant cultures were capable of utilizing lactose, at least partially, by an alternate pathway. He also observed differences in amino acid metabolism of the sensitive and resistant cultures in that the addition of certain amino acids to the medium accelerated the acid production of the resistant cultures but not that of the sensitive strain. Limited studies using C'4 labeled glucose showed that only 75 per cent of the lactic acid formed by the resistant culture came from glucose (Angelotti, Harper, and Weiser, 1955, Unpublished Data). Similar observations relative to the changes in the physiology of Escherichia coli upon the development of resistance to chlortetracycline and dihydrostreptomycin have been reported by Saz et al. (1956) and Roote and Polglase (1955), respectively. The present studies were conducted to investigate in greater detail the physiological differences relative to the acid production of the oxytetracycline sensitive and resistant S. lactis strain 10A cultures studied by Angelotti (1955).
Actor and Partner Effects of Attachment on Relationship Satisfaction and Sexual Satisfaction Across the Genders: An APIM Approach.

Previous studies found gender differences in relationship satisfaction and sexuality. We tested gender differences in associations between attachment, a lasting relationship determinant, and two outcomes, relationship and sexual satisfaction. This study improves on earlier research by examining these associations in one Actor-Partner-Interdependence-Model, making direct statistical testing between outcomes possible. Furthermore, a community and a distressed sample (N = 113 heterosexual couples each) were included to attempt replication across samples and to examine clinical implications. In both genders, actor attachment avoidance negatively affected relationship satisfaction and (with one exception) sexual satisfaction. Also in both genders, partner attachment avoidance negatively affected sexual satisfaction. However, whereas partner attachment avoidance influenced female relationship satisfaction, it did not affect male relationship satisfaction. The findings replicated across samples. Clinical implications are discussed.
Inflammation reduces the contribution of N‐type calcium channels to primary afferent synaptic transmission onto NK1 receptor‐positive lamina I neurons in the rat dorsal horn

N‐type calcium channels contribute to the release of glutamate from primary afferent terminals synapsing onto nocisponsive neurons in the dorsal horn of the spinal cord, but little is known of functional adaptations to these channels in persistent pain states. Subtype‐selective conotoxins and other drugs were used to determine the role of different calcium channel types in a rat model of inflammatory pain. Electrically evoked primary afferent synapses onto lumber dorsal horn neurons were examined three days after induction of inflammation with intraplantar complete Freund's adjuvant. The maximal inhibitory effect of the N‐type calcium channel blockers, ω‐conotoxins CVID and MVIIA, were attenuated in NK1 receptor‐positive lamina I neurons after inflammation, but the potency of CVID was unchanged. This was associated with reduced inhibition of the frequency of asynchronous‐evoked synaptic events by CVID studied in the presence of extracellular strontium, suggesting reduced N‐type channel contribution to primary afferent synapses after inflammation. After application of CVID, the relative contributions of P/Q and L channels to primary afferent transmission and the residual current were unchanged by inflammation, suggesting the adaptation was specific to N‐type channels. Blocking T‐type channels did not affect synaptic amplitude under control or inflamed conditions. Reduction of N‐type channel contribution to primary afferent transmission was selective for NK1 receptor‐positive neurons identified by post hoc immunohistochemistry and did not occur at synapses in laminae IIo or IIi, or inhibitory synapses. These results suggest that inflammation selectively downregulates N‐type channels in the terminals of primary afferents synapsing onto (presumed) nociceptive lamina I NK1 receptor‐positive neurons.
What can we learn from a decade of database audits? The Duke Clinical Research Institute experience, 1997—2006

Background Despite a pressing and well-documented need for better sharing of information on clinical trials data quality assurance methods, many research organizations remain reluctant to publish descriptions of and results from their internal auditing and quality assessment methods. Purpose We present findings from a review of a decade of internal data quality audits performed at the Duke Clinical Research Institute, a large academic research organization that conducts data management for a diverse array of clinical studies, both academic and industry-sponsored. In so doing, we hope to stimulate discussions that could benefit the wider clinical research enterprise by providing insight into methods of optimizing data collection and cleaning, ultimately helping patients and furthering essential research. Methods We present our audit methodologies, including sampling methods, audit logistics, sample sizes, counting rules used for error rate calculations, and characteristics of audited trials. We also present database error rates as computed according to two analytical methods, which we address in detail, and discuss the advantages and drawbacks of two auditing methods used during this 10-year period. Results Our review of the DCRI audit program indicates that higher data quality may be achieved from a series of small audits throughout the trial rather than through a single large database audit at database lock. We found that error rates trended upward from year to year in the period characterized by traditional audits performed at database lock (1997—2000), but consistently trended downward after periodic statistical process control type audits were instituted (2001—2006). These increases in data quality were also associated with cost savings in auditing, estimated at 1000 h per year, or the efforts of one-half of a full time equivalent (FTE). Limitations Our findings are drawn from retrospective analyses and are not the result of controlled experiments, and may therefore be subject to unanticipated confounding. In addition, the scope and type of audits we examine here are specific to our institution, and our results may not be broadly generalizable. Conclusions Use of statistical process control methodologies may afford advantages over more traditional auditing methods, and further research will be necessary to confirm the reliability and usability of such techniques. We believe that open and candid discussion of data quality assurance issues among academic and clinical research organizations will ultimately benefit the entire research community in the coming era of increased data sharing and re-use. Clinical Trials 2009; 6: 141—150. http://ctj.sagepub. com
Accelerated hepatitis B vaccination schedule among drug users: a randomized controlled trial.

BACKGROUND Hepatitis B vaccine provides a model for improving uptake and completion of multidose vaccinations in the drug-using community. METHODS The Drugs, AIDS, STDs, and Hepatitis (DASH) project conducted a randomized controlled trial among not-in-treatment current drug users in 2 urban neighborhoods. Neighborhoods were cluster-randomized to receive a standard behavioral intervention (which provided information on human immunodeficiency virus [HIV]) or an enhanced behavioral intervention (designed to increase acceptance of or adherence to the hepatitis B vaccination protocol). Participants within clusters were randomized to a standard vaccination schedule (vaccines at 0, 1, and 6 months) or an accelerated vaccination schedule (vaccines at 0, 1, and 2 months). The outcomes were completion of the 3-dose vaccine and seroprotection against hepatitis B virus (HBV). RESULTS Of participants with negative screening results for HIV and HBV, 77% accepted hepatitis B vaccination, and 75% of vaccinees received all 3 doses. Injection drug users (IDUs) on the accelerated schedule were significantly more likely to receive 3 doses (76%) than those on the standard schedule (66%; P = .04), although for drug users as a whole the corresponding adherence rates were 77% and 73%, respectively. No difference in adherence was observed between the behavioral intervention groups. Predictors of adherence were older age, African American race, stable housing, and alcohol use. Cumulative HBV seroprotection (≥10 mIU/mL) was gained within 12 months by 65% of those completing the schedule. Seroprotection at 6 months was greater for those on the accelerated schedule. CONCLUSION The accelerated vaccination schedule improves hepatitis B vaccination adherence among IDUs.
Show or Tell? Improving Agent Decision Making in a Tanzanian Mobile Money Field Experiment

When workers make operational decisions, the firm's global knowledge and the worker's domain-specific knowledge complement each other. Oftentimes workers have the final decision-making power. Two key decisions a firm makes when designing systems to support these workers are: 1) what guidance to deliver, and 2) what kind of training (if any) to provide. We examine these choices in the context of mobile money platforms? systems that allow users in developing economies to deposit, transfer, and withdraw money using their mobile phones. Mobile money has grown quickly, but high stockout rates of currency persist due to sub-optimal inventory decisions made by contracted employees (called agents). In partnership with a Tanzanian mobile money operator, we perform a randomized controlled trial with 4,771 agents over eight weeks to examine how differing types of guidance and training impact the agents' inventory management. We find agents who are trained in person and receive an explicit, personalized, daily text message recommendation of how much electronic currency to stock are less likely to stock out. These agents are more likely to alter their electronic currency balance on a day (rebalance). In contrast, agents trained in person but who receive summary statistics of transaction volumes or agents who are notified about the program and not offered in-person training do not experience changes in stockouts or rebalances. We observe no evidence of learning or fatigue. Agent-level heterogeneity in the treatment effects shows that the agents who handle substantially more customer deposits than withdrawals benefit most from the intervention.
Entrepreneurship and Sustainability Goals: The Need for Innovative and Institutional Solutions

The relationship between entrepreneurship and sustainable development has received considerable attention from academics and policymakers, as society searches for solutions leading to sustainability. The role of innovation and institutional quality in reaching sustainability goals is one of the key areas tackled by the current sustainable development debate, particularly in developing countries. Using a modified environmental Kuznets curve model, this study attempts to better improve our understanding of the critical roles of innovation, institutional quality, and entrepreneurship in the structural change toward a sustainable future in Africa. The empirical results show that both formal and informal entrepreneurship are conducive to less environmental quality and sustainability in 17 African countries where the contribution of informal entrepreneurship is much higher compared to the formal one. However, the relationship between entrepreneurship and sustainable development becomes strongly positive when the levels of innovation and institutional quality are higher. This research makes a contribution to this important emerging research area in that it clarifies conditions through which countries and firms in Africa can move toward more sustainable products and services. Formalizing the informal sector can lead to the improvement of the environmental and economic performance.
Disturbed brain activation during a working memory task in drug-naive adult patients with ADHD

Neuroimaging studies in attention-deficit/hyperactivity disorder (ADHD) have shown abnormalities in several brain areas including the frontostriatal circuitry and were mostly conducted in children and adolescents. We investigated 30 never-medicated adult ADHD patients (16 males) and 30 matched healthy control individuals. Functional magnetic resonance imaging was acquired during a working memory paradigm (n-back). Group activation maps and group differences of activation were calculated using voxel-based analyses. The generic activation pattern was more extended in the control group. In ADHD patients, significantly decreased activation was found in the right inferior parietal cortex. Disturbed parietal brain function may particularly contribute to inattention and working memory impairment in ADHD patients.
Value Co-Creation through multiple shopping channels: The interconnections with social exclusion and wellbeing

This study examines consumers’ value co-creation via several shopping channels including a traditional out-of-home shopping channel and “smart” channels where consumers use a computer, a mobile phone or social media. It focuses on the effect that value co-creation has on consumers’ shopping behaviour as well as on the perceived contribution of a shopping channel to their wellbeing, with a focus on individuals who perceive themselves as being socially excluded, particularly by mobility disability. The project was carried out in the USA using an online survey (n=1220). Social exclusion has a positive statistically significant effect on respondents’ selfconnection with all channels; for many socially excluded respondents the shopping channel has an important role in their lives. Self-connection with the channel has a positive effect on value cocreation and there is a positive relationship between value co-creation and the perceived contribution of the channel on wellbeing. When consumers help other individuals in their decision making they not only create value for the retailer and for other customers but also contribute positively to their own wellbeing. Importantly, for smart shopping channels where consumers use a computer or a mobile phone, the impact of value co-creation on the perceived contribution of these channels to consumer wellbeing are stronger for shoppers with a mobility disability than for those without such a disability.
New concepts on the epidemiological features of bovine besnoitiosis as determined by laboratory and field investigations.

1. General Introduction . 4 2. Definitions of terms and abbreviations 5 3. General aspects concerning materials and experimental methods used 6 4. Natural transmission of bovine besnoitiosis under conditions of cohabitation. S 5. Mechanical transmission of B. besnoiti by tsetse flies . 21 6. Mechanical transmission of B. besnoiti by tabanid flies 31 7. Mechanical transmission of B. besnoiti by stable flies . 54 8. Ingestion of B. besnoiti by mosquitoes 65 9. Artificial transmission of B. besnoiti by non-parenteral routes 70 10. A survey on the incidence of bovine besnoitiosis 83 11. The influence of quarantine measures on the incidence of bovine besnoitiosis. 93 12. Various specific attempts to produce clinical cases of bovine besnoitiosis 106 13. Observations on the time-interval between infection and the appearance of cysts in the scleral conjunctiva 122 14. General conclusions 127 15. Summary 132 16. Acknowledgements 135 17. References 135
On the Unintended Effects of Public Transfers: Evidence from EU Funding to Southern Italy

We study the relationship between the accrual of large financial transfers from a central level of government and the incidence of white collar crimes against public administration and public faith at the local level. We analyse the case of EU funding to Southern Italy and make use of within-municipality variation in the flow of funds between 2007 and 2014. We find a statistically significant effect of transfers on white collar crimes: our estimates suggest that in the absence of EU funding disbursements, the annual number of white collar crimes in Southern Italy would have been 4 per cent lower. We acknowledge that the evidence we provide cannot be taken as fully conclusive given the possible simultaneity of criminal activities and funding assignments and disbursements. Nevertheless, we provide evidence that the correlations we estimated between transfers and white collar crimes are unlikely to be spurious or due to confounding effects.
Association of Epstein-Barr virus with thymic carcinoma.

The Epstein–Barr virus is a ubiquitous B-cell lymphocytotropic virus that is known to cause infectious mononucleosis1 and lymphoproliferative disorders in immunodeficient patients2 and has been implicated in the genesis of Burkitt's lymphoma3 and primary intracerebral lymphoma.4 The association of Epstein–Barr virus with epithelial cells has been more puzzling, but recent studies have shown that the virus can penetrate and replicate in some epithelial cells.5 6 7 Undifferentiated nasopharyngeal carcinoma is consistently associated with Epstein–Barr virus.8 Another undifferentiated tumor with histopathological characteristics similar to those of undifferentiated nasopharyngeal carcinoma is the lymphoepithelioma-like carcinoma of the thymus. This subtype of thymic carcinomas has a .