Miracle-dz/UniFAR-FTUs huggingface dataset:
Maternal age at childbirth is associated with glucose metabolism in adult men

BACKGROUND: Although maternal age at childbirth tends to increase worldwide, studies investigating the effects of this trend on metabolic health in the offspring are scarce. OBJECTIVE: We aimed to determine whether maternal age at childbirth is associated with adult body composition and parameters reflecting metabolic health in a cohort of young, healthy men. METHODS: This study is part of a population-based sibling pair study in healthy men aged 25 to 45 years old. 689 subjects (mean age 33.9 +/- 5.4 years) for whom maternal data were available were included in the present analyses. Data collected in the study included birth weight, adult weight, height, DXA-derived body composition and blood pressure. Total cholesterol, glucose and insulin levels were determined in fasting serum samples. Insulin resistance was evaluated using the homeostasis model assessment of insulin resistance (HOMA-IR). Cross-sectional associations were investigated using linear mixed-effects modeling. RESULTS: Maternal age at childbirth was 27.0 ± 4.7 years (range 15-48) and was positively associated with birth weight (β=0.13; p=0.001). In their adult sons, maternal age at childbirth was inversely associated with fasting glucose levels (β=-0.12; p=0.001) and HOMA-IR values (β=-0.07; p=0.050) after adjustment for adult age and BMI. After further adjustment for birth weight, the associations between maternal age and glucose levels remained significant (β=-0.12; p=0.003), whereas the association between maternal age and HOMA-IR weakened (p=0.092) and birth weight became an independent inverse predictor of HOMA-IR (β=-0.07; p=0.039). No associations were found between maternal age and body composition, blood pressure or cholesterol levels. When subjects were divided into 4 groups according to maternal age at birth (<25, 25-29, 30-34 and ≥35 years), sons of mothers aged 30 to 34 at childbirth had significantly lower HOMA-IR values and fasting insulin levels compared to sons of mothers in the other age groups (p=0.007-0.015 for HOMA-IR, p=0.007-0.028 for insulin), whereas sons of mothers aged <25 had higher fasting glucose levels compared to sons of mothers aged 30-34 (p=0.010) and sons of mothers aged ≥35 (p=0.042). These associations were independent of adult age, BMI and birth weight. CONCLUSION: Maternal age at childbirth is associated with birth weight and glucose metabolism in adulthood. Part of the association between maternal age and insulin resistance might be mediated through birth weight.
Diffusive Sampling Of Air Pollutants In US Basins With Oil And Gas Development

Emissions from the oil and gas sector are important for climate change, ozone production and human health. Oil and gas leakage rates reported in the United States (US), estimated by relating measured methane fluxes with natural gas production, vary from less than 1% (e.g. Upper Green River Basin, (UGRB) in Wyoming) to over 6% (Uintah Basin, Utah). We demonstrate the applicability of the Pocket Diffusive (POD) sampler for scoping assessments of levels hydrocarbons and volatile polycyclic aromatic hydrocarbons (PAH) in areas heavily influenced by existing O&G development. We assess three US basins (Upper Green River, Uintah, and North Platte River), each with different characteristics, most importantly meteorology and emissions, which influence measured air quality. We contrast ambient concentrations of hydrocarbons (C4C12) and volatile PAHs at these basins and show important differences between measured levels of pollutants, including benzene. Our POD sampling results support previous findings of relatively elevated levels of aromatics in the Pinedale Anticline (UGRB) and relatively high alkane concentrations in the Uintah Basin. Concentrations of alkenes and PAH shows that these compound classes are at relatively low levels, and as such are of less concern in the assessed basins.
On feature augmentation for semantic argument classification of the Quran English translation using support vector machine

Research on the semantic argument classification requires semantically labeled data in large numbers, called corpus. Because building a corpus is costly and time-consuming, recently many studies have used existing corpus as the training data to conduct semantic argument classification research on new domain. But previous studies have proven that there is a significant decrease in performance when classifying semantic arguments on different domain between the training and the testing data. The main problem is when there is a new argument that found in the testing data but it is not found in the training data. This research carries on semantic argument classification on a new domain that is Quran English Translation by utilizing Propbank corpus as the training data. To recognize the new argument in the training data, this research proposes four new features for extending the argument features in the training data. By using SVM Linear, the experiment has proven that augmenting the proposed features to the baseline system with some combinations option improve the performance of semantic argument classification on Quran data using Propbank Corpus as training data.
Acétogénines d’Annonaceae et parkinsonismes atypiques : de la biodisponibilité de l’annonacine à l’exposition alimentaire.

Une importante proportion de formes atypiques de parkinsonismes a ete rapportee en Guadeloupe en 1999. Il ressort des etudes epidemiologiques menees sur place, que tous les patients atteints etaient de grands consommateurs de produits alimentaires et medicinaux de la famille des Annonaceae, et plus particulierement du genre Annona. De nombreux genres appartenant a cette famille renferment des molecules fortement cytotoxiques : les acetogenines d’Annonaceae. Leur presence dans les fruits d’Annona muricata a deja ete mise en evidence. Cependant, peu de donnees existent sur leur teneur en acetogenines dans ces fruits ou dans ceux d’especes proches. Par ailleurs, bien que l’annonacine, acetogenine principale d’A. muricata soit neurotoxique in vivo, aucune donnee quantitative de son acces au cerveau n’est disponible. Nous nous sommes donc attaches au cours de ce travail, a developper des methodes de dosage de l’annonacine par LC-MS/MS dans le plasma et le cerveau de Rat pour determiner sa biodisponibilite et la fraction a tropisme cerebral, dans le but de comprendre pourquoi des molecules si fortement cytotoxiques n’entrainaient pas d’intoxication aigue lors de l’exposition alimentaire. Nous avons par ailleurs developpe une methode de quantification des acetogenines totales par 1H RMN dans des extraits bruts de fruits, appliquee a des lots d’A. muricata d’origines variees. Une methode par LC-MS/MS a egalement ete developpee pour une description plus approfondie des acetogenines presentes dans des extraits bruts de fruits, appliquee a differents lots d’A. squamosa. Les fruits d’A. reticulata et d’A. glabra ont egalement fait l’objet d’investigations. Ces deux approches combinees ont contribue a ameliorer l’estimation de l’exposition aux acetogenines dans le cadre de l’alimentation.
Individual Development And Evolution The Genesis Of Novel Behavior

Thank you very much for downloading individual development and evolution the genesis of novel behavior. Maybe you have knowledge that, people have look numerous times for their chosen novels like this individual development and evolution the genesis of novel behavior, but end up in harmful downloads. Rather than reading a good book with a cup of coffee in the afternoon, instead they cope with some infectious bugs inside their desktop computer.
Lesão renal aguda em crianças: incidência e fatores prognósticos em pacientes gravemente enfermos

OBJETIVOS: Lesao renal aguda caracteriza-se pela reducao subita e, em geral, reversivel da funcao renal com perda da capacidade de manutencao da homeostase do organismo. Em pediatria, as principais causas de lesao renal aguda sao sepse, uso de drogas nefrotoxicas e isquemia renal nos pacientes criticamente enfermos. Nesses pacientes, a incidencia de lesao renal aguda varia de 20 a 30%, resultando em aumento da taxa de morbi-mortalidade de 40 a 90%. Este estudo tem como objetivo avaliar a incidencia de lesao renal aguda nos pacientes internados em unidade de terapia intensiva, classificar a gravidade da lesao renal aguda de acordo com o Pediatric Risk, Injury, Failure, Loss, End-Stage (pRIFLE), analisar a relacao entre lesao renal aguda e a gravidade atraves do Pediatric Index of Mortality (PIM) e estudar os fatores prognosticos associados. METODOS: Realizou-se um estudo prospectivo entre julho de 2008 a janeiro de 2009 dos pacientes internados na unidade de terapia intensiva pediatrica do Hospital Infantil Joana de Gusmao - Florianopolis (SC) - Brasil. Todos os pacientes foram analisados diariamente atraves do debito urinario e creatinina serica e classificados de acordo com pRIFLE. RESULTADOS: No periodo de acompanhamento foram internadas 235 criancas. A incidencia de lesao renal aguda foi de 30,6%, sendo que o pRIFLE maximo durante a internacao foi de 12,1% para R, 12,1% para I e 6,4% para F. A taxa de mortalidade foi de 12,3%. Os pacientes que evoluiram com lesao renal aguda apresentaram risco dez vezes maior de obito em relacao aos nao expostos. CONCLUSAO: Lesao renal aguda e uma entidade comum nos pacientes criticos. O diagnostico precoce a e instituicao imediata de medidas terapeuticas adequadas a cada situacao clinica podem alterar o curso e a gravidade do envolvimento renal reduzindo a morbi-mortalidade do paciente.
Inventio Herculaneis: per una rilettura dei giornali degli scavi di Ercolano

Dalla pubblicazione nel 1958 di Ercolano, i nuovi scavi da parte di Amedeo Maiuri, si ritiene che siano accessibili tutti i dati degli scavi svolti tra il 1927 e il 1941, nonostante l'assenza del secondo volume, rimasto inedito a causa della scomparsa dell'autore. Ogni volta che uno studioso si accinge ad utilizzare il sito di Ercolano nel corso delle sue ricerche, si riferisce come prima cosa, se non solo, al volume del Maiuri. Tuttavia, si puo dimostrare come l'attendibilita dei dati pubblicati dal Maiuri sia scarsa: la maggior parte del discorso si basa su un'osservazione del sito dopo il suo restauro piuttosto che sul risultato dello scavo. La visione ora condivisa di Ercolano corrisponde piu ad una percezione ideale e musealizzata che all'immagine emersa dallo scavo. Una rilettura complessiva dei giornali di scavo redatti tra il 1927 e il 1961, periodo nel quale A. Maiuri era Soprintendente agli scavi, permette di dare una nuova percezione della citta. I problemi di comprensione di questi rapporti quotidiani sono numerosi, ma il piu importante da superare e quello della localizzazione delle descrizioni eseguite giorno dopo giorno: ne la visione del sito - ovviamente parziale - ne i punti di riferimenti topografici corrispondono alla nostra conoscenza attuale. Ad esempio, la numerazione dei cardini cambia tre volte, secondo le ipotesi di localizzazione dello scavo proposte nel confronto con la carta generale del sito ricavata dai disegni settecenteschi. Tuttavia, grazie ad una rilettura accurata dell'insieme di questi giornali, si puo seguire l'avanzamento dei lavori di disseppellimento e restituire Ercolano cosi come apparse durante gli scavi e non come venne inventata dal Maiuri. I cambiamenti che emergono vanno dal piu banale dettaglio alla necessaria revisione di tutta una casa, con revisioni sussidiare della percezione dello spazio urbano. Ad esempio, la descrizione della bottega che si trova nella facciata della Casa di Nettuno ed Anfitrite (V, 6), come venne redatta all'atto dello scavo non specifica ne anfore sullo scaffale - trovato vuoto -, ne derrate conservate nei dolii - le fave esposte provengono da un'anfora trovata al primo piano. La Casa a Graticcio e sicuramente l'esempio per il quale la distorsione tra i dati di scavo e lo stato conosciuto e la piu ampia. I giornali di scavo permettono non solo di ricollocare tutti i mobili di legno nelle stanze dove sono stati trovati - permettendo cosi di capire meglio la divisione della casa in quattro appartamenti di dimensioni molto diverse - ma anche di restituire un ballatoio che andava molto oltre il marciapiede per guadagnare piu spazio possibile, rendendo molto buia la parte meridionale del cardo IV. Gran parte delle distorsioni tra i dati direttamente ricavati dallo scavo e il modo col quale sono stati presentati e pubblicati si puo spesso spiegare con le contingenze legate al restauro. La volonta del Maiuri di presentare in un modo molto didattico le vestigia di Ercolano e un'altra spiegazione per questi travisamenti che devono essere tutti studiati per capire al meglio l'invenzione di Ercolano.
A Tractable Approach to Joint Transmission in Multiuser Visible Light Communication Networks

In this paper, an analytical model for the coverage analysis of multiuser visible light communication (VLC) networks is presented, taking into account the cooperation among access points (APs). Specifically, the cooperation is realized through joint transmission (JT), where the coordinated APs jointly transmit data to users in a noncoherent or coherent manner to reduce the inter-cell interference and enhance the useful signal power. Using a second-order moment matching approach, we find approximate distribution functions of the signal power and interference, and derive tractable results for the network coverage probability based on the signal-to-interference-plus-noise ratio (SINR). For both noncoherent and coherent JT, the derived coverage probabiklity are further simplified into closed forms when the communication link is interference-limited. We validate the derived results through Monte Carlo simulations and apply them to study behaviors and trends of the network under various parameter settings. Results show that JT can improve the coverage performance of the network and coherent JT can provide higher performance gains than its noncoherent counterpart, at the cost of higher implementation complexities.
Vacation homes and regional economic development

ABSTRACT This paper studies the relationship between vacation homes and regional development. Vacation homes are often in peripheral regions with relatively low standards of living. Seasonal residents contribute income to these areas but make local housing costlier and may have negative effects on local housing, labour, and product markets. The paper introduces a model that demonstrates how demand for housing from seasonal residents affects the welfare of local residents. It then studies the effects of a Norwegian policy that obliges homeowners in certain municipalities to reside on their properties. The policy is shown to increase local population, employment, wages and house prices.
A ``Critical'' Tracking Task for Manual Control Research

A ``critical'' tracking task is developed in which a human operator is required to stabilize an increasingly unstable first-order controlled element up to the critical point of loss of control. Servo theory and operator describing function measurements are used to validate the basic assumptions, and an automatically paced critical task mechanization is described. The results show that the task does constrain the operator's behavior as intended, and that the critical instability depends primarily on the operator's effective time delay while tracking. A number of applications for the critical task are reviewed, including secondary workload research, control and measurement of operator and controlled element gain, and display research.
Dicontinuation rates of SSRIs and tricyclic antidepressants

(1997). Although the result of the compar ison of newer tricyclic agents and SSRIs is not surprising, we were unclear about some methodological points relevant to the conclusions. In the treatment studies of newer TCAS and SSRIs, patients discontinue treatment for various reasons such as lack of efficacy, adverse events or early treatment response. Also, there may be wider variations in the dosage ranges for some newer tricyclics and SSRIs compared with others, and in the rate of dosage escalation to achieve the BNF dosages. We were not clear whether these sources of heterogeneity had been ad dressed, or if not, whether these would have affected the conclusions reached. A more serious problem is the method used in the trials to establish lack of efficacy and what constitutes an adverse event. Some studies use different outcome measures and different response criteria on the basis of change in score of these measures. Some studies use different methods to enquire about possible adverse events or adjust for the effects of preceding somatic and cogni tive complaints at study entry. These factors may affect the comparability of such studies. Also, we would be interested to know whether there were differences in the time onset of discontinuation (i.e. â€ ̃¿ early' or â€ ̃¿ late') in these studies. Another important point is the likely rate of discontinuation of antidepressants after response in the acute phase of illness, that is in the maintenance phase; as the studies referenced mostly appear to have been of short duration. If such information was available this would be of great interest, as some clinicians argue that SSRIs might be more acceptable in maintenance treatment than tricyclics, yet we are not aware of any good evidence that this holds for newer classes of tricyclic antidepressants such as lofepramine.
Ruby: The Programming Language

[font face="Verdana, Helvetica" size="2"An ideal companion to many introductory computer science courses, as well as an excellent primer, Ruby: The Programming Language offers an accessible introduction to this easy to learn, open-source language. This overview describes the fundamentals of the object-oriented Ruby language and discusses how students can quickly construct complete web applications with ease. Ruby: The Programming Language will excite students on the capabilities of computer programming and inspire them to delve deeper into the computer science discipline.
Reply: Letter to the Editor

Steven De Peuter is a post-doctoral research fellow of the Research Foundation – Flanders (FWO-Vlaanderen). The contribution of Johan W.S. Vlaeyen was supported by the Odysseus Grant ‘‘The Psychology of Pain and Disability Research Program” funded by the Research Foundation – Flanders (FWO-Vlaanderen). None of the authors reports a conflict of interest. The authors thank Ann Meulders and Martien Schrooten for their constructive input.
High concentration causticizing: possibilites and limitations. Using the process, capacity gains can be seen in the evaporation plant

On a elabore un nouveau procede de caustification, dont on a evalue la viabilite au moyen d'essais en laboratoire et de simulation sur ordinateur. Les resultats de l'etude montrent qu'il est possible de produire, avec ce nouveau procede, une liqueur blanche ayant une teneur en alcali actif, une causticite et un degre de reduction eleves. On examine les donnees d'equilibre necessaires a la reaction de basification a de tres fortes concentrations, ainsi que des donnees de solubilite applicables au systeme NaOH-Na 2 CO 3 -Na 2 SO 4 -NaCl-H 2 O.
Blood transfusion safety in sub‐Saharan Africa: A literature review of changes and challenges in the 21st century

Access to a safe, adequate blood supply has proven challenging in sub‐Saharan Africa, where systemic deficiencies spanning policy, collections, testing, and posttransfusion surveillance have long been recognized. Progress in transfusion safety in the early 2000s was in large part due to intervention by the World Health Organization and other foreign governmental bodies, coupled with an influx of external funding.
Income distribution, structural competitiveness and financial fragility of the Greek economy

ABSTRACT The aim of this paper is to examine the growth prospects of the Greek economy, after the implementation of the Economic Adjustment Programs (EAPs). The main focus is on the impact of investment, and the structural competitiveness of the productive sector, on effective demand and the financial fragility of corporations. For this purpose, a Post-Keynesian SVAR model is developed which connects functional income distribution and the regime of accumulation, with the structural competitiveness and the non-performing loans of corporations. The findings indicate that the distribution of income and fiscal consolidation as established after the implementation of the EAPs have destabilized the economy both in macroeconomic and financial terms. The structural competitiveness of the Greek economy is particularly weak, the regime of accumulation is not profit-led, while the non-performing loans are in a negative relation with the capacity utilization ratio. In this respect, policies that aim to increase the capacity utilization ratio will determine the sustainability of the macro-financial system of Greece.
Manuka honey mouthwash does not affect oral mucositis in head and neck cancer patients in New Zealand

Abstract Oral mucositis is an unavoidable side effect of radiation therapy to the head and neck, which can compromise patient health and quality of life. This study investigates the effect of manuka honey on the extent of oral mucositis in head and neck patients in New Zealand. A total of 28 patients were recruited; 10 patients received standard care and 18 patients were given additional manuka honey. Honey was used three times a day; assessment included: extent of oral mucositis using a multi-site mucositis scoring system, weight and quality of life. The first six patients, randomised to the honey arm, used undiluted honey and pulled out in the first week because of extreme nausea, vomiting and stinging sensations in the mouth. The next 12 honey patients used a honey mouthwash (diluted 1:3). Six of these patients completed the trial and four more completed the first 4 weeks of the trial. Eight control patients completed the trial. In contrast to previous honey trials in Malaysia, Egypt, Iran and India, diluted manuka honey did not decrease the extent and onset of radiation-induced oral mucositis but did appear to ameliorate radiation-induced weight loss and increase quality of life in the absence of cisplatin chemotherapy.