Miracle-dz/UniFAR-FTUs huggingface dataset:
Visual Cognition Influences Early Vision

A partly occluded visual object is perceptually filled in behind the occluding surface, a process known as amodal completion or visual interpolation. Previous research focused on the image-based properties that lead to amodal completion. In the present experiments, we examined the role of a higher-level visual process—visual short-term memory (VSTM)—in amodal completion. We measured the degree of amodal completion by asking participants to perform an object-based attention task on occluded objects while maintaining either zero or four items in visual working memory. When no items were stored in VSTM, participants completed the occluded objects; when four items were stored in VSTM, amodal completion was halted (Experiment 1). These results were not caused by the influence of VSTM on object-based attention per se (Experiment 2) or by the specific location of to-be-remembered items (Experiment 3). Items held in VSTM interfere with amodal completion, which suggests that amodal completion may not be an informationally encapsulated process, but rather can be affected by high-level visual processes.
Relationship between the volume of craniotomies for cerebral aneurysm performed at New York state hospitals and in-hospital mortality.

BACKGROUND AND PURPOSE After a craniotomy for cerebral aneurysm, postoperative mortality can be significant. Previous studies have shown that hospitals performing frequent high-risk procedures (such as coronary artery bypass) have a lower mortality than hospitals where these procedures are performed infrequently. METHODS The Statewide Planning and Research Cooperative System of the New York State Department of Health reviewed all discharges in New York State from 1987 through 1993 for the diagnoses of subarachnoid hemorrhage and/or cerebral aneurysm and for patients with the procedure code for craniotomy for ruptured or unruptured cerebral aneurysm. In-hospital mortality and length of stay were examined in relation to the volume of craniotomies for aneurysm performed at each individual hospital. RESULTS A total of 15,376 discharges for subarachnoid hemorrhage and 5638 craniotomies for aneurysm were tabulated in 208 hospitals. For all patients who underwent craniotomy for ruptured cerebral aneurysm (n = 4034), there was a 43% (95% confidence interval, 29% to 57%) reduction in mortality rate in hospitals performing more than 30 craniotomies per year for cerebral aneurysm compared with hospitals performing less surgery (8.8% versus 15.5%, P < .0001). For all patients who underwent craniotomy for unruptured cerebral aneurysm (n = 1604), there was an identical 43% (95% confidence interval, 14% to 73%) reduction in mortality in hospitals performing more than 30 craniotomies per year for cerebral aneurysm (4.6% versus 8.1%, P = .0087). CONCLUSIONS Hospitals that frequently perform aneurysm operations have lower mortality rates for patients undergoing craniotomy for cerebral aneurysm than hospitals that perform fewer operations.
CMB lensing constraints on dark energy and modified gravity scenarios

Weak gravitational lensing leaves a characteristic imprint on the cosmic microwave background temperature and polarization angular power spectra. Here, we investigate the possible constraints on the integrated lensing potential from future cosmic microwave background angular spectra measurements expected from Planck and EPIC. We find that Planck and EPIC will constrain the amplitude of the integrated projected potential responsible for lensing at 6% and 1% level, respectively, with very little sensitivity to the shape of the lensing potential. We discuss the implications of such a measurement in constraining dark energy and modified gravity scalar-tensor theories. We then discuss the impact of a wrong assumption on the weak lensing potential amplitude on cosmological parameter inference.
A study of the genetic variability of human respiratory syncytial virus in Croatia, 2006–2008

Human respiratory syncytial virus (HRSV) is a common etiological agent of acute lower respiratory tract disease in infants. The molecular epidemiology of HRSV in Croatia over four consecutive seasons (from 2006 to 2008) was investigated. A total of 72 HRSV samples were chosen from 696 screened cases in a pediatric clinic in Zagreb. Molecular characterization of HRSV revealed the predominance of HRSV group B viruses in the first two epidemic seasons and HRSV group A viruses in the next two seasons. According to the phylogenetic analysis, NA1 and BA9 were the predominant circulating HRSV genotypes detected during the study. Overall, 82.9% of all HRSV A strains belonged to the NA1 genotype. The HRSV B genotype BA9, detected in two consecutive seasons (2006 and 2007), was the predominant circulating HRSV B genotype, accounting for 80.6% of all HRSV B strains. This study provides data on the circulation pattern of HRSV genotypes in Croatia and their molecular characterization. J. Med. Virol. 84:1985–1992, 2012. © 2012 Wiley Periodicals, Inc.
Why Anger and Disappointment Affect Other’s Bargaining Behavior Differently

In two experiments, the authors investigated the interpersonal effects of anger and disappointment in negotiations. Whereas previous research focused on the informational inferences that bargainers make based on others’ emotions, this article emphasizes the importance of affective reactions. The findings of this study show that anger evoked a complementary emotion (fear) in targets when reported by a high-power bargainer but evoked a reciprocal emotion (anger) when reported by a low-power bargainer. This reciprocal anger led participants to offer less to low-power counterparts who reported anger. Disappointed bargainers, however, evoked a complementary emotion (guilt) in participants and increased offers, regardless of the bargainer’s power position.
Backpropagation Applied to Handwritten Zip Code Recognition

The ability of learning networks to generalize can be greatly enhanced by providing constraints from the task domain. This paper demonstrates how such constraints can be integrated into a backpropagation network through the architecture of the network. This approach has been successfully applied to the recognition of handwritten zip code digits provided by the U.S. Postal Service. A single network learns the entire recognition operation, going from the normalized image of the character to the final classification.
Extracting Spatiotemporal Word and Semantic Representations from Multiscale Neurophysiological Recordings in Humans

With the recent advent of neuroimaging techniques, the majority of the research studying the neural basis of language processing has focused on the localization of various lexical and semantic functions. Unfortunately, the limited time resolution of functional neuroimaging prevents a detailed analysis of the dynamics involved in word recognition, and the hemodynamic basis of these techniques prevents the study of the underlying neurophysiology. Compounding this problem, current techniques for the analysis of highdimensional neural data are mainly sensitive to large effects in a small area, preventing a thorough study of the distributed processing involved for representing semantic knowledge. This thesis demonstrates the use of multivariate machine-learning techniques for the study of the neural representation of semantic and speech information in electro/magnetophysiological recordings with high temporal resolution. Support vector machines (SVMs) allow for the decoding of semantic category and word-specific information from non-invasive electroencephalography (EEG) and magnetoenecephalography (MEG) and demonstrate the consistent, but spatially and temporally distributed nature of such information. Moreover, the anteroventral temporal lobe (avTL) may be important for coordinating these distributed representations, as supported by the presence of supramodal category-specific information in intracranial recordings from the avTL as early as 150ms after auditory or visual word presentation. Finally, to study the inputs to this lexico-semantic system, recordings from a high density microelectrode array in anterior superior temporal gyrus (aSTG) are obtained, and the recorded spiking activity demonstrates the presence of single neurons that respond specifically to speech sounds. The successful decoding of word identity from this firing rate information suggests that the aSTG may be involved in the population coding of acousto-phonetic speech information that is likely on the pathway for mapping speech-sounds to meaning in the avTL. The feasibility of extracting semantic and phonological information from multichannel neural recordings using machine learning techniques provides a powerful method for studying language using large datasets and has potential implications for the development of fast and intuitive communication prostheses. iv TABLE OF CONTENTS Abstract . iii Table of
Desmopressin: therapeutic limitations in children and adults with inherited coagulation disorders

Desmopressin (DDAVP), a synthetic analogue of vasopressin has been successfully used in the treatment of type I von Willebrand's disease (VWD), mild factor VIII (FVIII) deficiency and intrinsic platelet function defects (PFDs) for almost three decades. However, there is limited published data documenting its efficacy and the reliability of circulating plasma FVIII:C as a surrogate marker of response to therapy in VWD. We report the haemostatic response to DDAVP in 133 consecutive patients (91 type I VWD, 20 mild FVIII deficiency and 22 PFDs). Minimal therapeutic response to DDAVP (0·3 µg/kg) was defined by normalization 30 min post‐ infusion of bleeding time for PFDs, factor VIII:C (FVIII:C) for mild haemophilia A, and von Willebrand factor antigen (VWF:Ag), von Willebrand factor functional activity (VWF:Ac) and FVIII:C for VWD. Nine out of 91 (10%) VWD patients failed to achieve minimal therapeutic response to DDAVP; plasma FVIII:C levels were an unreliable surrogate marker of DDAVP response as 6 out of 9 (67%) of these patients had normal post‐infusion FVIII:C levels. Five out of the 20 (25%) patients with mild FVIII deficiency and 5 out of 22 (23%) patients with PFDs failed to achieve a minimal therapeutic response to DDAVP. DDAVP is an effective therapy in the majority of patients with type I VWD, PFDs and mild FVIII deficiency. The significant failure rate associated with this therapy supports the recent recommendations that response should be assessed in all patients at the time of diagnosis. FVIII:C is an unreliable guide of response to DDAVP in patients with VWD and therefore VWF:Ag and VWF:Ac should also be assessed. Failure to demonstrate the response of VWF:Ag, VWF:Ac and FVIII:C to DDAVP in patients with VWD is likely to increase the risk of haemorrhagic complications in patients with bleeding episodes or who are undergoing surgery.
A prospective study of cardiorespiratory fitness and breast cancer mortality.

PURPOSE Physical activity may protect against breast cancer. Few prospective studies have evaluated breast cancer mortality in relation to cardiorespiratory fitness (CRF), an objective marker of physiologic response to physical activity habits. METHODS We examined the association between CRF and risk of death from breast cancer in the Aerobics Center Longitudinal Study. Women (N = 14,811), aged 20 to 83 yr with no prior breast cancer history, received a preventive medical examination at the Cooper Clinic in Dallas, Texas, between 1970 and 2001. Mortality surveillance was completed through December 31, 2003. CRF was quantified as maximal treadmill exercise test duration and was categorized for analysis as low (lowest 20% of exercise duration), moderate (middle 40%), and high (upper 40%). At baseline, all participants were able to complete the exercise test to at least 85% of their age-predicted maximal heart rate. RESULTS A total of 68 breast cancer deaths occurred during follow-up (mean = 16 yr). Age-adjusted breast cancer mortality rates per 10,000 woman-years were 4.4, 3.2, and 1.8 for low, moderate, and high CRF groups, respectively (trend P = 0.008). After further controlling for body mass index, smoking, drinking, chronic conditions, abnormal exercise ECG responses, family history of breast cancer, oral contraceptive use, and estrogen use, hazard ratios (95% CI) for breast cancer mortality across incremental CRF categories were 1.00 (referent), 0.67 (0.35-1.26), and 0.45 (0.22-0.95) (trend P = 0.04). CONCLUSIONS These results indicate that CRF is associated with a reduced risk of dying from breast cancer in women.
Cochlear implantation in mitochondrial deafness due to A7445G mutation

Abstract Objective This study aimed to determine if cochlear implantation (CI) improved speech discrimination in the New Zealand pedigree with the A7445G mitochondrial DNA (mtDNA) mutation and sensorineural hearing loss (SNHL). Methods Nine patients had their speech discrimination and pure tone audiograms evaluated. Pre- and post-implant results were compared. Type of CI and patient age at implantation was recorded. Results Speech discrimination testing shows greatly improved functional hearing after CI in this group of patients. Discussion Individuals with mtDNA-related SNHL should be identified by screening and offered assessment for CI suitability because functional hearing improves after CI.
From Subadditive Inequalities of Singular Values to Triangle Inequalities of Canonical Angles

The singular values of matrices $A,B,C\in\mathbb{C}^{m\times n}$ with $C=A+B$ satisfy an extensive list of subadditive inequalities discovered by K. Fan, V.B. Lidskii, H. Wielandt, R.C. Thompson, A. Horn, and so on. These inequalities still hold when we apply a nonnegative concave function to each of the singular values involved, as shown recently by M. Uchiyama and J.C. Bourin. The main purpose of this paper is to show that all of these singular value inequalities can be translated into canonical angle inequalities. The bridge between the singular values and the canonical angles is given by a “multiplicative Pythagorean identity” relating the direct rotations between three subspaces.
Transformation by Fos proteins requires a C-terminal transactivation domain

The Fos family of proteins now includes seven members: the retroviral proteins FBR-v-Fos and FBJ-v-Fos and the cellular proteins c-Fos, FosB, FosB2, Fra1, and Fra2. Four proteins (FBR-v-Fos, FBJ-v-Fos, c-Fos, and FosB) transform established rodent fibroblast cell lines, while three (FosB2, Fra1, and Fra2) do not. As all family members display sequence-specific DNA-binding activity as part of a heterodimeric complex with Jun proteins, other features must account for the differences in transforming potential. We demonstrate here that all transforming members have a C-terminal transactivation domain that is lacking in nontransforming members. The nontransforming proteins Fra1 and Fra2 can be converted to transforming proteins by fusion of a transactivation domain from either FosB or VP16. We also demonstrate that differences in the basic region-leucine zipper domain affecting either the affinity or sequence specificity of DNA binding are not determinants of the difference in transforming potential among members of the Fos family. The results further define the functional requirements for transformation by Fos proteins and suggest that the subunit composition of AP1 complexes is an important determinant of mitogenic signalling capability.
Adaptations in maximal motor unit discharge rate to strength training in young and older adults

Six young (mean = 23 years) and 6 older (mean = 76 years) adults participated in isometric resistance training 5 days/week for 6 weeks. The task involved isometric fifth finger abduction. Maximal motor unit discharge rates (MUDRs) were obtained from the abductor digiti minimi of each hand at 0, 2, 14, and 42 days of training using a quadrifilar needle electrode and automatic spike recognition software. In agreement with previous findings, maximal MUDR at baseline was significantly lower in older adults (P < 0.001), averaging 51.5 (±17.13) HZ in young and 43.3 (±14.88) HZ in older adults. In response to resistance training, maximal voluntary force increased 25% in young and 33% in older subjects (P < 0.001). Maximal MUDR increased significantly (11% young, 23% older) on day 2 [F(3,36) = 2.58, P < 0.05], but in older subjects returned to baseline levels thereafter. These adaptations in abductor digiti minimi MUDR suggest a two‐part response to strengthening fifth finger abduction: early disinhibition followed by altered MU activation. © 2001 John Wiley & Sons, Inc. Muscle Nerve 24:542–550, 2001
Study of the influence of test methods on DC pollution flashover voltage of insulator strings and its flashover process

The influence of different test methods on dc pollution flashover voltage of insulator strings is presented in this paper. In addition, the relationship among the flashover voltages obtained by different voltage applied methods is put forward. Subsequently, the pollution flashover phenomenon is investigated using the insight from high-speed photography, and the comprehensive magnitude and orientation of forces on partial arcs is analyzed during the propagation. Thus, a new electrical circuit model consisting of a surface arc of length x1 and air arc of length x2 in series with a resistance representing the wet pollution layer supplied by a constant voltage is built. The results obtained from the model indicate that the main reason that makes the exponent b describing the influence of pollution on flashover voltage varying with the configuration and material of insulators is the difference of partial arc fluttering degree for insulators.
OX40L-OX40 Interactions: A Possible Target for Gastrointestinal Autoimmune Diseases

Gastrointestinal (GI) autoimmune diseases have a high incidence in developed countries, such as Canada and the US. Some common GI autoimmune diseases include ulcerative colitis and Crohn's Disease. These conditions are not only unpleasant for the patient, but also present a heavy burden on the healthcare system. OX40L, a member of the tumor necrosis family, has been identified as a key player in the pathological inflammatory response, which characterizes GI autoimmune diseases. OX40L is expressed in many cell types, including antigen presenting cells (APCs), T-cells, vascular endothelial cells, mast cells, and natural killer cells. The importance of OX40L-OX40 interactions in inflammatory autoimmune diseases is becoming more evident through different animal models, ranging from nematode models to mouse models. This literature review attempts to summarize the current literature regarding the role of OX40L-OX40 interactions in GI autoimmune inflammatory diseases and comment on its potential for treatment. Various databases, including OVID MedLine and PubMed were used to retrieve articles regarding the role of OX40L-OX40 interactions in the pathogenesis of autoimmune diseases. These articles were then reviewed and summarized in a comprehensive manner. OX40L-OX40 interactions have a strong potential for becoming a treatment target; however, there are still many gaps in the present knowledge, which need to be addressed before more definitive treatments can emerge. It is also suggested that upstream events leading to OX40L activation, such as thymic stromal lymphopoietin (TSLP)-activated dendritic cells, be explored as treatment targets as well. OX40L-OX40 interaction is a possible venue for treatment of GI diseases; however, the underlying mechanisms of actions and the downstream effects of OX40L knock down need to be investigated.
Evidence for Physiological Vascular Occlusion in Stems of Cut Gerbera cv. Hongyan

The aim of this paper was to assess the effect of catechol (CH), as a peroxidase inhibitor, and 8-hydroxyquinoline citrate (HQC), as a bacterial inhibitor, on keeping the quality of Gerbera Jamesonii cv. Hongyan cut flowers, known to be limited by vascular occlusion. Blockage in the stem xylem vessels of cut gerbera was studied using light and scanning electron microscope. The results showed that some stem xylem vessels of the cut flowers were blocked during the vase period, and the blockage consisted of some amorphous or physiological deposition and rod-shaped bacteria located within the 5cm stem end of the cut flower. In addition, CH (1.0mM) or 8-HQC (0.45mM) decreased the blockage of stems and reduced the bacterial growth in the vase solution, but extended the vase life without statistical significance. The combination of CH (0.5 or 1.0 mM) and 8HQC (0.45mM) decreased the blockage and inhibited the bacteria more than CH or 8HQC alone, and extended the vase life significantly (P ≤ 0.05).
Safety and functionality of transhepatic hemodialysis catheters in chronic hemodialysis patients.

PURPOSE We aimed to investigate the safety and functionality of tunneled transhepatic hemodialysis catheters in chronic hemodialysis patients. METHODS Thirty-eight patients (20 women aged 56±10 years and 18 men aged 61±11 years) with transhepatic tunneled hemodialysis catheters were evaluated. The date of the first transhepatic catheterization, indications, procedure details, functional time periods of catheters, reasons for the removal or revision of catheters, catheter-related complications, and current conditions of patients were retrospectively analyzed. RESULTS A total of 69 catheters were properly placed in all patients (100% technical success) under imaging guidance during the 91-month follow-up period. The functionality of 35 catheters could not be evaluated: five catheters were removed because of noncomplication related reasons (surgical fistulas were opened in two cases [2/35, 5.7%], transplantation was performed in three cases [3/35, 8.6%]), 18 patients died while their catheters were functional (18/35, 51.4%), and 12 catheters were still functional at the time of the study (12/35, 34.3%). The functionality of catheters was evaluated the remaining 34 catheters that necessitated revision because of complications. Furthermore, only half of the catheters were functional on day 136 when evaluated using Kaplan-Meier analysis. The four main complications were thrombosis (16/34, 47%; complication rate of 0.37 days in 100 catheters), infection (8/34, 23.5%; 0.18 days in 100 catheters), migration (8/34, 23.5%; 0.18 days in 100 catheters), and kinking (2/34, 6%; 0.04 days in 100 catheters). CONCLUSION Transhepatic venous catheterization is a safe and functional alternative route in chronic hemodialysis patients without an accessible central venou route. The procedure can be performed with high technical success and low complication rates under imaging guidance.