Miracle-dz/UniFAR-FTUs huggingface dataset:
French CrowS-Pairs: Extending a challenge dataset for measuring social bias in masked language models to a language other than English

Warning: This paper contains explicit statements of offensive stereotypes which may be upsetting.Much work on biases in natural language processing has addressed biases linked to the social and cultural experience of English speaking individuals in the United States. We seek to widen the scope of bias studies by creating material to measure social bias in language models (LMs) against specific demographic groups in France. We build on the US-centered CrowS-pairs dataset to create a multilingual stereotypes dataset that allows for comparability across languages while also characterizing biases that are specific to each country and language. We introduce 1,679 sentence pairs in French that cover stereotypes in ten types of bias like gender and age. 1,467 sentence pairs are translated from CrowS-pairs and 212 are newly crowdsourced. The sentence pairs contrast stereotypes concerning underadvantaged groups with the same sentence concerning advantaged groups. We find that four widely used language models (three French, one multilingual) favor sentences that express stereotypes in most bias categories. We report on the translation process from English into French, which led to a characterization of stereotypes in CrowS-pairs including the identification of US-centric cultural traits. We offer guidelines to further extend the dataset to other languages and cultural environments.
Divide and Denoise: Learning from Noisy Labels in Fine-Grained Entity Typing with Cluster-Wise Loss Correction

Fine-grained Entity Typing (FET) has made great progress based on distant supervision but still suffers from label noise. Existing FET noise learning methods rely on prediction distributions in an instance-independent manner, which causes the problem of confirmation bias. In this work, we propose a clustering-based loss correction framework named Feature Cluster Loss Correction (FCLC), to address these two problems. FCLC first train a coarse backbone model as a feature extractor and noise estimator. Loss correction is then applied to each feature cluster, learning directly from the noisy labels. Experimental results on three public datasets show that FCLC achieves the best performance over existing competitive systems. Auxiliary experiments further demonstrate that FCLC is stable to hyperparameters and it does help mitigate confirmation bias. We also find that in the extreme case of no clean data, the FCLC framework still achieves competitive performance.
Effect of Resistance Training Frequency on Neuromuscular Performance and Muscle Morphology after Eight Weeks in Trained Men.

The purpose of this study was to investigate the chronic effects of training muscle groups 1 day per week vs. 2 days per week on neuromuscular performance and morphological adaptations in trained men with the number of sets per muscle group equated between conditions. Participants were randomly assigned in 2 experimental groups: 1 session·wk per muscle group (G1, n = 10), where every muscle group was trained once a week with 16 sets or 2 sessions·wk per muscle group (G2, n = 10), where every muscle group was trained twice a week with 8 sets per session. All other variables were held constant over the 8-week study period. No significant difference between conditions for maximal strength in the back squat or bench press, muscle thickness in the elbow extensors, elbow flexors, or quadriceps femoris, and muscle endurance in the back squat and bench press performed at 60% 1RM was detected. Effect size favored G2 for some outcome measurements, suggesting the potential of a slight benefit to the higher training frequency. In conclusion, both G1 and G2 significantly enhance neuromuscular adaptations, with a similar change noted between experimental conditions.
Cross-Lingual UMLS Named Entity Linking using UMLS Dictionary Fine-Tuning

We study cross-lingual UMLS named entity linking, where mentions in a given source language are mapped to UMLS concepts, most of which are labeled in English. Our cross-lingual framework includes an offline unsupervised construction of a translated UMLS dictionary and a per-document pipeline which identifies UMLS candidate mentions and uses a fine-tuned pretrained transformer language model to filter candidates according to context. Our method exploits a small dataset of manually annotated UMLS mentions in the source language and uses this supervised data in two ways: to extend the unsupervised UMLS dictionary and to fine-tune the contextual filtering of candidate mentions in full documents.We demonstrate results of our approach on both Hebrew and English. We achieve new state-of-the-art (SOTA) results on the Hebrew Camoni corpus, +8.9 F1 on average across three communities in the dataset. We also achieve new SOTA on the English dataset MedMentions with +7.3 F1.
[Emergency surgery for neoplastic left colon obstruction: resection and primary anastomosis (RPA) versus Hartmann resection (HR)].

UNLABELLED This retrospective study compares: hospitalization time, morbidity and mortality (patients operated for neoplastic occlusion of the left colon in emergency, without perforation), considering hanestesiologic risk and surgical technique (RPA versus RH). MATERIALS AND METHODS From April 1999 to February 2003 the Emergency Surgery of AORN of Caserta has operated, in urgency, 60 neoplastic patients with left colon occlusion realizing: 46 (76.5%) RPA [36 ASA < or = III, low hanestesiologic risk (LAR), 10 ASA = or > IV high hanestesiologic risk (HAR)], 12 (20%) RH (2 LAR and 10 HAR) 2 (3.5%) palliative colostomics. RESULTS 36 LAR patients with RPA had 5% of specific complications and 5% of medical complications. 2 LAR patients with R-H: no complication. 10 HAR patient with RPA brought 10% of specific complications and 10% of medical complications. 10 HAR patients with RH had 20% of specific complications and 10% of general complications. The middle hospitalization of LAR patients with RPA was 11 days versus 9 days of RH pz. (equal hanestesiologic risk ). The HAR pz. , treated with RPA, had as middle hospitalization 15 ggs in comparison to the 9 ggs of the HRA pz. treated with RH. MORTALITY 1/36 for LAR pz. with RPA (3%), and 0/0 for LAR pz. with RH; 1/10 for HAR pz, with RPA (10%) and 1/10 for HAR pz. with RH (10%). CONCLUSIONS Resection and primary anastomosis, (correct indications and expert surgeon), gives prevalence of complications and mortality similar to the repeated surgical procedure, a better life quality, but an higher number of post-operating hospitalisation days.
A prospective randomized multicenter study of tacrolimus in combination with sirolimus in renal-transplant recipients

Background. Recently, sirolimus (SRL) was introduced as an immunosuppressant in solid-organ transplantation. This study evaluated combinations of SRL and tacrolimus (Tac). Methods. This 6-month study investigated the safety and efficacy of Tac and steroids in combination with three different doses of SRL in renal-transplant recipients. A total of 104 patients were randomized in four groups: one group received Tac and steroids (control n=28), and three groups also received the following daily SRL doses: 0.5 mg (TacSRL0.5, n=25), 1 mg (TacSRL1, n=25), or 2 mg (TacSRL2, n=26). Tac doses were adjusted to whole-blood trough levels. Steroids were tapered from 20 mg per day to 5 mg per day. The SRL groups underwent a second randomization to discontinue SRL at either month 3 or 5. Results. At month 6, patient survival rates were 100%, 100%, 96.0%, and 100%, and graft survival rates were 96.4%, 84.0%, 88.0%, and 84.6%, respectively. The overall safety profile was similar in all groups. The incidences of infections during months 1 to 3 were similar in all groups (control 46.4%, TacSRL0.5 32.0%, TacSRL1 56.0%, TacSRL2 46.2%). The 3-month incidences of hypercholesteremia (cholesterol >240 mg/dL or low-density lipoprotein cholesterol >160 mg/dL) were 21.4%, 36.0%, 48.0%, and 50.0% (P =0.019). Lipid levels improved after withdrawal of SRL. The 3-month incidences of biopsy-proven acute rejection were 28.6% (control), 8.0% (TacSRL0.5), 8.0% (TacSRL1), and 3.8% (TacSRL2) (P =0.014). Conclusion. Tac in combination with low doses of SRL provides a very effective and safe regimen.
Assessing the incidence of gestational diabetes and neonatal outcomes using the IADPSG guidelines in comparison with the Carpenter and Coustan criteria in a Belgian general hospital

Abstract We have conducted a systematic universal screening for gestational diabetes mellitus (GDM) since 2008, following the criteria outlined by the International Association of Diabetes and Pregnancy Study Group (IADPSG) since 2011. However, we recently replaced the IADPSG standards with those established by the Belgian French Language Gynecologists and Obstetricians Group (GGOLFB). These new criteria indicate GDM when fasting plasma glucose (FPG) is ⩾0·92 g/l at the beginning of pregnancy or when an orally provoked hyperglycaemia test (75 g of glucose) between the twenty-fourth and twenty-eighth week results in an FPG of ⩾0·92 g/l and/or ⩾1·80 g/l after 1 hour and/or ⩾1·53 g/l after 2 hours. The goal of this retrospective study was to evaluate the incidence of GDM, neonatal outcomes, and the use of insulin therapy 21 months post-implementation of the IADPSG criteria within our centre. A total of 393 patients were diagnosed with GDM from January 2009 to December 2012. After applying the new criteria, the incidence of GDM rose significantly from 8 to 23% (P<0·0001). However, there were no significant changes in the proportion of GDM patients requiring insulin therapy (34·2% versus 34·7%) or the rate of foetal large for gestational age (11·2% versus 8·8%). In addition, the ⩾90% percentile decreased non-significantly from 96·3±0·6% to 94·3±0·70% (P = 0·057), whereas the lower quartiles and the proportion of cesarean deliveries (27·0% versus 25·6%) did not change significantly. Therefore, non-targeted screening significantly increased the incidence of GDM in our centre without significantly decreasing large for gestational age or the number of cesarean deliveries.
Using cardiovascular features to classify state changes during cooperation in a simulated bomb defusal task

Teams of two individuals worked together in a high-intensity simulated bomb diffusing task. Half the teams were given icebreaker social time to increase comfort and familiarity with each other and the remaining half of the teams served as controls and did not meet until the task began. Electrocardiography and impedance cardiography were recorded to examine cardiac changes during task cooperation. Changes in ventricular contractility showed that individuals who had taken part in the icebreaker showed increased task engagement over time whereas controls showed the opposite. Data also trended to show that icebreaker participants were in a challenge state and controls were in a threat state during the final thirty seconds of bomb defusal. Finally, we show that a set of cardiac features can be used to classify participant data as belonging to the icebreaker or control groups with an accuracy as high as 88%.
Laser induced clot formation in blood treated by EDTA

Patients under systemic (ethylenediaminetetraacetic acid) EDTA are at risk of hemorrhage for any accidental trauma even the superficial ones. This research is a trial to use 980 nm wavelength laser light to provide coagulation for such patients in a local region without collateral thermal damage. Material and Method: 980 nm Diode laser operating in a continuous mode (CW) was incident on human blood treated with EDTA inDurhamtubes. The used parameters were (2.25, 3, 3.75 and 6.75) W output power for variable exposure times (1, 3, 9 and 27) s. Results: A homogenous clot was performed at 4327.84 J/cm2 deposited energy density with the absence of any thermal stress in the blood. Conclusion: 980 nm laser wavelength provides a local photochemical bond break of the anticoagulant enhancing blood coagulation for medically compromised patients.
Relationship Patterns in Alexithymia: A Study Using the Core Conflictual Relationship Theme Method

Background: Alexithymia is a disturbance in regulating affective states. Clinical observations suggest that alexithymic patients relate to others in a specific way. This paper explores whether specific relationship or transference patterns are typical of alexithymia. Sampling and Methods: Relationship patterns were assessed by means of the Core Conflictual Relationship Theme method, standard categories version. This method examines transference patterns and was applied to clinical interview data collected from a sample (n = 31) of mental health outpatients. Alexithymia was assessed by means of a score on the 20-item Toronto Alexithymia Scale corrected for the degree of depression (measured by the Beck Depression Inventory-II). Data were analysed by means of the leaps and bounds regression algorithm for selecting optimal subsets of indicators and by bootstrapping to determine 95% confidence intervals. Results: First, we observed that alexithymia can be meaningfully explained by typical wishes, typical subjective perceptions of how others respond and one’s own typical responses to others. This result indicates that the more marked a patient’s alexithymic traits are, the more probable it is that specific transference themes come to the fore. Second, a set of three core indicators of trait alexithymia was mapped: little concern about being good to others, a strong perception of others as cooperative, and weak levels of reacting to others and to conflict by means of somatic symptoms. Conclusion: Alexithymia is related to a double interpersonal indifference: not much is expected from others, nor is there a personal urge to fulfill the expectations of others. Moreover, in alexithymia somatic symptoms proved to be non-reactive to interpersonal situations. Implications for diagnosis and treatment are highlighted. Limitations of our study are that alexithymia was only assessed with a self-report measure and that conclusions are based only upon data from a heterogeneous mental health sample.
Study on hydrophobicity transfer of RTV coatings based on a modification of absorption and cohesion theory

Room temperature vulcanized (RTV) silicone rubber coatings are used increasingly on outdoor high voltage (HV) insulators subjected to heavy pollution. An important property of the RTV coatings is the ability to restore the surface hydrophobicity after a pollutant layer has built up on the surface, which can suppress the development of leakage currents, dry band arcing and flashover. The present study analyzes the hydrophobicity and the hydrophobicity transfer of RTV coatings and the factors that affected the hydrophobicity. A modification of absorption and cohesion theory was used to analyze the hydrophobicity transfer mechanisms and the influences of temperature, polydimethylsiloxane (PDMS) molecular weight, degree of cross-linking, extent of soluble and non-soluble components, and the pollutant properties. The hydrophobicity transfer of RTV coatings was also investigated with various conditions of contaminations and various factors, which affect the hydrophobicity transfer, including the composition of RTV coatings and the outside conditions. Results show that the hydrophobicity transfer of RTV coatings is not only dependent on compositions but also on factors of circumstance. The analysis also explains the obvious difference between the hydrophobicity transfer of RTV coatings to kieselguhr and kaolin based on a particle and surface analysis using the Brunauer, Emmett and Teller (BET) method, which explains the relationship between a BET surface area and the hydrophobicity transfer of the RTV coatings
A Novel Strategy for Retrospective Exposure Assessment in the Norwegian Silicon Carbide Industry

The objective was to construct a retrospective job-exposure matrix (JEM) for the Norwegian silicon carbide industry. More than 3300 historical total dust measurements were available (1967–2005); however, there were few measurements of other agents. Total dust measurements were therefore used as the basis for the JEM, and a novel method was developed to estimate exposure to other agents. Multiple linear regression models were developed to describe historical exposure to total dust. Exposure estimates were extrapolated backward to periods without exposure data by adjustments for process and work-hour related changes. An exposure assessment study was performed where total dust was sampled in parallel with fibers or respirable dust. The respirable dust was analyzed for the content of quartz, cristobalite, and silicon carbide. Mixed-effect models were developed to estimate the exposure to these agents from total dust exposure, plant, and job group. Exposure to asbestos and polycyclic aromatic hydrocarbons was assigned qualitatively. Multiple linear regression models of total dust described historical exposure best in the furnace department (R2 adj = 0.49–0.74). Models in the other departments explained less variance (R2 adj = 0.12–0.32). Exposure determinants and total dust explained a substantial proportion of the between- (70–100%) and within-worker (8.0–54%) variance in the mixed-effect models. The relative bias between available historical measurements and the estimated exposure to dust components varied between –39% (fiber) and 40% (quartz). However, corrections were not considered necessary due to limitations in the historical data. The component-specific metrices were sufficiently different from each other (rPearson < 0.7), with the exception of total and respirable dust (rPearson = 0.84) and total dust and cristobalite (rPearson = 0.72), and will enable component-specific epidemiologic analyses in the future. Improved and less correlated estimates of exposure levels for the different components in the dust were obtained with the updated exposure assessment. Due to limitations in the measurement data, assumptions had to be made, especially in the period before 1967. [Supplementary materials are available for this article. Go to the publisher's online edition of Journal of Occupational and Environmental Hygiene for the following free supplemental resource: a file containing tables outlining multiple linear regression models for prediction of total dust exposure in the processing departments of Norwegian SiC producing plants, evaluation of the predictive abilities of the reduced total dust models, and mixed models for pedicting exposure to fibers and respirable quartz, cristobalite, non-fibrous silicon carbide and respirable dust from total dust exposure. ]
Rearrangement of Actin Cytoskeleton Mediates Invasion of Lotus japonicus Roots by Mesorhizobium loti[C][W]

Infection thread–dependent invasion of legume roots by rhizobia leads to internalization of bacteria into the plant cells, which is one of the salient features of root nodule symbiosis. We found that two genes, Nap1 (for Nck-associated protein 1) and Pir1 (for 121F-specific p53 inducible RNA), involved in actin rearrangements were essential for infection thread formation and colonization of Lotus japonicus roots by its natural microsymbiont, Mesorhizobium loti. nap1 and pir1 mutants developed an excess of uncolonized nodule primordia, indicating that these two genes were not essential for the initiation of nodule organogenesis per se. However, both the formation and subsequent progression of infection threads into the root cortex were significantly impaired in these mutants. We demonstrate that these infection defects were due to disturbed actin cytoskeleton organization. Short root hairs of the mutants had mostly transverse or web-like actin filaments, while bundles of actin filaments in wild-type root hairs were predominantly longitudinal. Corroborating these observations, temporal and spatial differences in actin filament organization between wild-type and mutant root hairs were also observed after Nod factor treatment, while calcium influx and spiking appeared unperturbed. Together with various effects on plant growth and seed formation, the nap1 and pir1 alleles also conferred a characteristic distorted trichome phenotype, suggesting a more general role for Nap1 and Pir1 in processes establishing cell polarity or polar growth in L. japonicus.
The economic burden of anemia in cancer patients receiving chemotherapy.

BACKGROUND Anemia is one of the most common hematologic complications of cancer and cytotoxic treatment. The economic burden associated with anemia in patients with malignancy has not yet been extensively studied. METHODS Patients receiving chemotherapy within 6 months of initial cancer diagnosis were identified in a database of commercial health-care service claims and encounters. Patients with anemia were identified through a coded diagnosis of anemia, transfusion, or erythropoietin treatment. Exponential conditional mean models and a decomposition analysis were used to analyze mean 6-month health-care expenditures. RESULTS Twenty-six percent (26%) of 2760 cancer patients with recently diagnosed invasive cancer treated with chemotherapy had anemia. Mean (SD) 6-month unadjusted total expenditures were 62,499 dollars (78,016 dollars) for anemic patients and 36,871 dollars (52,308 dollars) for nonanemic patients (P < 0.0001), with inpatient services representing the largest cost differential between the groups. The adjusted mean 6-month expenditure for the average anemic patient receiving chemotherapy was 57,209 dollars. If anemic patients had the same average health status as nonanemic patients, their predicted 6-month expenditures would have been 19% lower (46,237 dollars). Alternatively, if anemic patients had the same expenditure structure or parameter estimates as nonanemic patients, their predicted expenditures would have been 51% lower (27,847 dollars). Thus, for any given health status, treating a patient who is anemic is associated with considerably higher expenditures. CONCLUSIONS Anemia among cancer patients receiving chemotherapy is associated with a substantial burden in terms of direct medical costs. Implications for the treatment of anemia are suggested by this research and should be confirmed in prospective studies.
SkipBERT: Efficient Inference with Shallow Layer Skipping

In this paper, we propose SkipBERT to accelerate BERT inference by skipping the computation of shallow layers. To achieve this, our approach encodes small text chunks into independent representations, which are then materialized to approximate the shallow representation of BERT. Since the use of such approximation is inexpensive compared with transformer calculations, we leverage it to replace the shallow layers of BERT to skip their runtime overhead. With off-the-shelf early exit mechanisms, we also skip redundant computation from the highest few layers to further improve inference efficiency. Results on GLUE show that our approach can reduce latency by 65% without sacrificing performance. By using only two-layer transformer calculations, we can still maintain 95% accuracy of BERT.
A gastrointestinal anti-infectious biotherapeutic agent: the heat-treated Lactobacillus LB

Experimental in vitro and in vivo studies support the hypothesis that heat-treated, lyophilized Lactobacillus acidophilus LB cells and concentrated, neutralized spent culture medium conserve the variety of pharmacological, antimicrobial activities of the live probiotic strain against several infectious agents involved in well-established acute and persistent watery diarrhoea and gastritis. Heat-treated cells and heat-stable secreted molecules trigger multiple strain-specific activities explaining the therapeutic efficacy of L. acidophilus LB. This review discusses the current body of knowledge on the antimicrobial mechanisms of action exerted by L. acidophilus LB demonstrated in in vitro and in vivo experimental studies, and the evidence for the therapeutic efficacy of this anti-infectious biotherapeutic agent proved in randomized clinical trials for the treatment of acute and persistent watery diarrhoea associated with several intestinal infectious diseases in humans.