Miracle-dz/UniFAR-FTUs huggingface dataset:
Early Measures of Hemoconcentration and Inflammation Are Predictive of Prolonged Hospitalization From Post– Endoscopic Retrograde Cholangiopancreatography Pancreatitis

Objectives Hemoconcentration markers are predictors of severe acute pancreatitis but have not been specifically evaluated in post–endoscopic retrograde cholangiopancreatography pancreatitis (PEP). Methods Case-control study of patients undergoing ERCP for suspected sphincter of Oddi dysfunction. We identified patients with PEP (PEP positive) and controls (PEP negative) in a 1:2 ratio. blood urea nitrogen (BUN) and hematocrit (Hct) were measured before procedure, upon admission, and 24 hours later. Preprocedure levels of BUN and Hct were analyzed to control for confounders. Among the PEP-positive patients, BUN level, Hct level, and systemic inflammatory response syndrome are compared between severe and mild/moderate cases. Results There were 149 PEP-positive patients, including 18 patients (12.1%) with severe PEP and 301 PEP-negative controls. After adjusting, higher preprocedure BUN level (odds ratio [OR], 1.05 [1.01, 1.10]; P < 0.02) and pancreatic sphincterotomy (OR, 1.60 [1.01, 2.55]; P < 0.05) were associated with PEP, whereas older age (OR, 0.98 [0.96, 0.99]; P < 0.02) and a greater body mass index (OR, 0.97 [0.94, 0.99]; P < 0.03) with a lower rate. Difference in BUN level of 0.0 or greater (failure to decline) had a sensitivity of 71% and a specificity of 79% for differentiating severe from mild/moderate PEP. Patients with severe PEP were more likely to have systemic inflammatory response syndrome upon admission (44.4% [21.5, 67.4]) and after 24 hours (61.1% [38.6, 83.6] versus mild/moderate (9.2% [4.2, 14.1], 10.6% [5.4,16.0]; P < 0.0001 for each). Conclusions Preprocedure BUN level is associated with the development of PEP. The preprocedure BUN level and failure of the BUN level to decline during the first 24 hours are associated with prolonged hospitalization.
Soil phosphorus and disturbance influence liana communities in a subtropical montane forest

Questions: What are the effects of soil, topography, treefall gaps, tree species composition, and tree density on liana species composition and total liana abundance? Location: A 6-ha permanent plot in a subtropical montane forest in northwest Argentina. Methods: Multiple regressions were used to quantify associations of liana species composition and total liana abundance with edaphic, disturbance and tree community variables. Gradients in liana and tree species composition were quantified using principal components analysis (PCA). Results: Liana species composition was correlated most strongly with soil phosphorus concentration (R 2 5 0.55). Total liana abundance increased with phosphorus and the density of recent treefall gaps (R 2 5 0.60). Conclusions: In our study area, liana composition and abundance are most strongly correlated with features of the physical environment, rather than host tree characteristics. Our results support the hypothesis that recent increases in liana abundance in mature tropical forests may be related to increased rates of gap formation.
Field Research on the Relationship between Stress and Disease Activity in Rheumatoid Arthritis a

ABSTRACT: We review empirical evidence from two field studies for the role of stressful life events in disease flare‐ups among patients with rheumatoid arthritis (RA). RA patients were expected to be more vulnerable psychologically, and physiologically, to stressful events in their everyday lives than other arthritis patients without an autoimmune disease. Findings from two studies are reviewed both for their substantive contribution, but also to provide guidance on measurement issues in future field research of this kind. One study included 41 patients with RA, who were interviewed weekly and called to a clinic for blood work and joint examinations when their levels of interpersonal stress increased significantly. A second study used a similar design but included comparison samples of patients with osteoarthritis (OA) and healthy controls of similar age and the same gender as the RA sample. The findings provided support for the proposition that interpersonal stressors are predictive of increases in disease activity. Not all RA patients, however, showed these relationships, and there was evidence that some participants with OA who were depressed also showed higher disease activity following interpersonal stressors. Significant individual differences in the stress‐disease relationship were uncovered that deserve greater attention in future studies. Important improvements in the assessment of stressful events and refinements in panel study design are also presented as guides to research on the role of stress in disease processes.
Clitoral electromyography.

PURPOSE The clitoris has several histomorphological and functional similarities to the penis. In this study we evaluated spontaneous and evoked electromyography activity in the clitoris. MATERIALS AND METHODS We evaluated 11 healthy female volunteers with clitoral electromyography using a concentric needle electrode placed intracorporeally. The hand, foot and genital sympathetic skin responses, and spontaneous electrodermal activity were simultaneously recorded with silver surface electrodes. Another concentric needle electrode was placed subdermally on the mons pubis to differentiate clitoral activity from possible artifact. After recording spontaneous electromyography and electrodermal activity the left median nerve was stimulated to record evoked clitoral activity, and the sympathetic skin response in the hand, foot and genital regions. RESULTS There was spontaneous electromyography activity in the corpus clitoris. All dermal sites, including the hand, foot and genital regions, showed spontaneous electrodermal activity. No spontaneous activity was recorded from the subdermal needle electrode. Distraction of attention and coughing increased the amplitude and frequency of spontaneous clitoral electromyography and electrodermal activity at all sites. After stimulating the left median nerve all sites except that of the subdermal needle electrode showed evoked activity. CONCLUSIONS The demonstrated evoked and spontaneous clitoral electromyography activity seems to indicate a sympathetic tonus of the corpus clitoris, as recorded from the corpus cavernosum of the penis in human males. Clitoral electromyography may be a useful objective assessment tool for evaluating female sexual dysfunction as well as genital autonomic innervation.
Fractures in German elite male soccer players.

BACKGROUND Aim of this retrospective cohort study was to identify fracture epidemiology and off times after different types of fractures in German male elite soccer players from the first division Bundesliga based on information from the public media. METHODS Exposure and fracture data over 7.5 consecutive seasons (2009/10 until the first half of 2016/17) were collected from two media-based register (transfermarkt.de® and kicker.de®). RESULTS Overall, 357 fractures from 290 different players were recorded with an incidence of 0.19/1000 hours of exposure (95% CI: 0.14-0.24). Most fractures in German elite soccer players involved the lower extremities (35.3%), the head/face (30.3%) and the upper extremities (24.9%). The median off time after a fracture in German elite male professional soccer in 7.5 Season was 51.1 days (range 0-144). The number of fractures per 100 players per season decreased between 2009 and 2016. There was no significant difference in overall fracture incidence when comparing players at different position (P=0.11). Goalkeepers have a significantly (P<0.02) higher likelihood of suffering hand and finger fractures and they are significantly (P<0.03) less prone of suffering foot fractures, cranial and maxillofacial fractures (P<0.04). compared to outfield players. CONCLUSIONS This study can confirm that male professional soccer teams experience 1-2 fractures per season in German elite soccer. The incidence of fractures in elite German soccer players decreased between 2009 and 2016. The most fractures occur in the lower extremities and there is no difference in overall fracture risk for players at different playing positions. The information from our study might be of a great importance to medical practitioners, soccer coaches and soccer manager.
Memoirs on Differential Equations and Mathematical Physics Volume 32, 2004, 29–58 G. Khuskivadze and V. Paatashvili ON ZAREMBA’S BOUNDARY VALUE PROBLEM FOR HARMONIC FUNCTIONS OF SMIRNOV CLASSES

Analogously to Smirnov classes of analytic functions, Smirnov classes of harmonic functions are introduced and mixed Zaremba’s boundary value problem is studed in them, i.e., the problem of constructing a harmonic function when on a part of the boundary its values are given, while on the remaining part the values of its normal derivative. 2000 Mathematics Subject Classification. 35J05,35J25.
Association for Information Systems AIS Electronic Library ( AISeL ) ACIS 2011 Proceedings Australasian ( ACIS ) 2011 Going Beyond Operations with Enterprise Systems

Enterprise Systems have become the preferred type of IT systems in most large organizations in the last few decades. These, large-scale, integrated, packaged software suites have been shown to enable operational efficiency by several prior studies . This paper reviews a number of such studies and identifies a gap in the literature. The primary contribution of this paper is that it proposes that Enterprise Systems can create business value, in addition to operational efficiency, by achieving innovation (in product, process and alliance) and enabling better strategic decision making in the adopting firms. The paper also provides empirical evidence using detailed secondary data that supports this proposition. In addition, this study also provides additional evidence for concepts identified in earlier research. This paper reports on the first study of a research-inprogress and this model will be tested further through extensive primary case studies
Demographic Features and Neuropsychological Correlates in a Cohort of 200 Patients with Vascular Cognitive Decline Due to Cerebral Small Vessel Disease

Introduction: Vascular dementia is the second most common form of dementia and is potentially reversible. Small vessel disease (SVD) closely mimics degenerative dementia in view of its sub-acute onset and progressive course. Therefore, unlike large vessel disease, Hachinski Ischemic scale score may not always reflect vascular cognitive decline resulting in diagnostic and therapeutic confusions. Therefore, there is a need for detailed neuropsychological assessment for various cognitive domains for early identification of vascular cognitive decline as it carries a very good long term prognosis for cognitive morbidity, unlike degenerative dementias. Patients and Methods: This prospective study involves thorough domain based neuropsychological assessment of patients with a radiological diagnosis of SVD involving the following parameters-digit forward and backward, category fluency, color trails, stick test, logical memory test, and bender gestalt test. Magnetic resonance imaging scans done using 3-tesla machines and SVD graded using Fazekas visual scale. Results: The mean Hachinskis score was less sensitive for differentiating vascular dementia from degenerative dementia. However, the domain based neuropsychological scores were highly sensitive showing statistically significant impairment in all 6 domains tested and compared with Fazekas 1-3 grades in imaging. Discussion and Conclusion: This study aimed at establishing an early diagnosis of vascular mild cognitive impairment using domain wise neuropsychological testing and correlating it with radiological scores. Hachinskis score is more sensitive for large vessel disease in view of acute onset and step-like progression as against steady progression in SVD. However, domain-wise testing was highly sensitive in identifying early cognitive impairment in patients with SVD, and early therapeutic interventions are highly rewarding.
Census of Antarctic Marine Life SCAR-Marine Biodiversity Information Network CHAPTER 9 . 2 . PAST , PRESENT AND FUTURE STATE OF PELAGIC HABITATS IN THE ANTARCTIC OCEAN

Claude DE BROYER is a marine biologist at the Royal Belgian Institute of Natural Sciences in Brussels. His research interests cover structural and ecofunctional biodiversity and biogeography of crustaceans, and polar and deep sea benthic ecology. Active promoter of CAML and ANDEEP, he is the initiator of the SCAR Marine Biodiversity Information Network (SCAR-MarBIN). He took part to 19 polar expeditions. Philippe KOUBBI is professor at the University Pierre et Marie Curie (Paris, France) and a specialist in Antarctic fi sh ecology and biogeography. He is the Principal Investigator of projects supported by IPEV, the French Polar Institute. As a French representative to the CCAMLR Scientifi c Committee, his main input is on the proposal of Marine Protected Areas. His other fi eld of research is on the ecoregionalisation of the high seas.
The biology and behavior of Triatoma barberi (Hemiptera: Reduviidae) in Mexico. III. Completion of the life cycle, adult longevity, and egg production under optimal feeding conditions.

Laboratory studies on molting, mortality, adult longevity, mating, egg production, and the feeding behavior of 1st-instar nymphs were conducted on a cohort of 37 individuals of Triatoma barberi (Hemiptera: Reduviidae) of identical under optimal feeding conditions and controlled temperature and humidity. Newly emerged 1st-instar nymphs fed between days 3 and 5 following hatch. Molting patterns were irregular in all nymphal instars, in spite of the frequency with which blood meals were offered ($\bar x$ = once every 4.2 days). The range between the first and last individual molting was 14, 130, 220, 409, and 343 days for the 1st, 2nd, 3rd, 4th, and 5th instar, respectively, resulting in a wide discrepancy between the chronologic and physiologic ages of individuals in the cohort. The first adults emerged at 112 days (3.7 months) following hatch, the last adult at 455 days (1 year, 3 months). Mortality in the laboratory was low, with 3% of the 1st instars, 3% of the 2nd instars, and 14% of the 5th instars dying prior to molting. Survival in well-fed adults was high ($\bar x$ = 178 days for females, 222 days for males), with no significant difference between the sexes. Egg production in well-fed females was relatively low for triatomine ($\bar x$ = 0.8 eggs per female per postfeeding day).
A selenium and vitamin E responsive condition in the laying hen.

Abstract Diets composed mostly of low selenium corn and torula yeast were fed to laying hens to produce a selenium and/or vitamin E deficiency. The basal diet was also supplemented with 101. U. of vitamin E per kg. , or 0.10 mg. /kg. selenite selenium, or a combination of vitamin E and selenium. Hens fed the basal diet decreased in egg production during the third month and for the remainder of the experiment, a decrease which was mostly corrected by vitamin E, and completely corrected by selenium. Fertility and hatchability of eggs were also low on the basal diet, and were also partly corrected by vitamin E, and completely corrected by selenium. The selenium content of lyophilized egg white and yolk is reported along with the selenium content of several tissues. Gross deficiency signs of the laying hen are also described.
The Neuropsychology and Neurology of Sexual Deviance: A Review and Pilot Study

Current neurological hypotheses of paraphilia posit that sexual deviance is associated with frontal and/or temporal lobe damage. This broad conception is based on few investigations, however, and the first goal of this study was to review the existing data derived from neuropsychiatry, neuroimaging and neuropsychology. It is concluded that although fronto-temporal dysfunctions are sporadically reported among sexual offenders, the evidence is scarce and it might not be specific to this type of offending. The second objective of this investigation was to gather preliminary neuropsychological data with more homogeneous subgroups of sexual offenders. A profile of lower-order executive dysfunctions (e.g. sustained attention and inhibition) and verbal deficits with intact or good capacities for higher-order executive functioning (e.g. reasoning and cognitive flexibility) and visuo-spatial processing was preferentially found among sexual offenders, suggesting basal fronto-temporal anomalies. Importantly, pedophiles were more consistently and severely impaired than rapists of adults. However, this basal fronto-temporal profile is not characteristic of sexual deviance, as it is also found in association with delinquency and criminality in general. Future neuropsychological and brain imaging studies should consider subgroups of sexual offenders and recruit non-sexual violent persons and non-violent individuals in order to disentangle the complex relations between brain anomalies and sexual deviance.
Effect of wetted surface area on friction, pressure, wave and total drag of a kayak

Abstract Using theoretical principles, the components of drag (friction D F, pressure D PR and wave D W) of a single-seat kayak were analysed. The purpose was to examine the effect of changes in wetted surface area due to changes in kayaker’s weight and the relative contribution of D F, D PR and D W to the total passive drag as function of velocity. The total passive drag values were based on experimental data collected in a single-seat kayak. Three different kayaker simulated weights were tested – 65, 75 and 85 kg. D F was the drag component that contributed the greatest percentage (between 60 and 68% at 5.56 m/s the top velocity tested) to the total passive drag for all the velocities tested and simulated weights. D W was the most affected by the increase in kayaker’s simulated weight, mainly when comparing 65/75 to 85 kg. Results support the importance of a kayak design selection that minimises the kayak’s drag for the individual weight of the kayaker. Also, the results suggest that the path for better hydrodynamic kayak performance should seek changes that can reduce D F, D PR and D W with D F offering the most potential to reduce passive drag.
Life expectancy, expected years of life lost and survival of hemodialysis and peritoneal dialysis patients.

BACKGROUND Expected years of life lost (EYLL) in dialysis patients are rarely discussed. This study compared life expectancy, EYLL and survival between hemodialysis (HD) and peritoneal dialysis (PD) patients. METHODS Adults who underwent maintenance dialysis at National Taiwan University Hospital from 1995 to 2006 were followed up until December 2007. Kaplan-Meier analysis and a constant excess hazard model were used to estimate and project long-term survival. EYLL was calculated by subtracting the life expectancy of patients from that of age- and sex-matched referents. HD patients were then matched with PD patients on age, sex and diabetes mellitus (DM). Life expectancy, EYLL and survival between the 2 groups were compared. Mortality risks were determined by the Cox model. RESULTS Before matching, the 305 HD patients were older than the 428 PD patients (62.4 ± 13.7 vs. 53.1 ± 16.7 years; p<0.0001). More HD patients had DM (HD vs. PD, 29.2% vs. 20.6%; p=0.0072). Life expectancy and EYLL of HD patients were 8.8 and 11.5 years, compared with those of PD patients (19.9 and 7.4 years). After matching, life expectancy (p=0.790) and EYLL (p=0.793) of both groups (236 patients each) were similar. Age (adjusted hazard ratio [AHR] = 1.07; 95% confidence interval [95% CI], 1.05-1.09) and DM (AHR=3.81; 95% CI, 2.28-6.36) were independent mortality predictors. For diabetic patients who underwent HD, a better survival rate was observed (AHR=0.24; 95% CI, 0.11-0.53). CONCLUSIONS After matching, HD and PD patients had similar life expectancy and EYLL. Survival was better for diabetic patients if they received HD.
Characterization of the Envelope Glycoproteins Associated with Infectious Hepatitis C Virus

ABSTRACT Hepatitis C is caused by an enveloped virus whose entry is mediated by two glycoproteins, namely, E1 and E2, which have been shown to assemble as a noncovalent heterodimer. Despite extensive research in the field of such an important human pathogen, hepatitis C virus (HCV) glycoproteins have only been studied so far in heterologous expression systems, and their organization at the surfaces of infectious virions has not yet been described. Here, we characterized the envelope glycoproteins associated with cell-cultured infectious virions and compared them with their prebudding counterparts. Viral particles were analyzed by ultracentrifugation, and the envelope glycoproteins were characterized by coimmunoprecipitation and receptor pulldown assays. Furthermore, their oligomeric state was determined by sedimentation through sucrose gradients and by separation by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) under nonreducing conditions. In sucrose gradient analyses, HCV envelope glycoproteins were associated with fractions containing the most infectious viral particles. Importantly, besides maturation of some of their glycans, HCV envelope glycoproteins showed a dramatic change in their oligomeric state after incorporation into the viral particle. Indeed, virion-associated E1 and E2 envelope glycoproteins formed large covalent complexes stabilized by disulfide bridges, whereas the intracellular forms of these proteins assembled as noncovalent heterodimers. Furthermore, the virion-associated glycoprotein complexes were recognized by the large extracellular loop of CD81 as well as conformation-sensitive antibodies, indicating that these proteins are in a functional conformation. Overall, our study fills a gap in the description of HCV outer morphology and should guide further investigations into virus entry and assembly.
Potential anticancer activity of carvone in N2a neuroblastoma cell line

Carvone (CVN) is a monocyclic monoterpene found in the essential oils of Mentha spicata var. crispa (Lamiaceae) and Carum carvi L. (Apiaceae) plants and has been reported to have antioxidant, antimicrobial, anticonvulsant, and antitumor activities. The beneficial health properties of CVN have encouraged us to look into its anticancer activity. To the best of our knowledge, reports are not available on the anticancer activity of CVN in cultured primary rat neuron and N2a neuroblastoma (NB) cells. Therefore, the present study is an attempt toward exploring the potential anticancer activity of CVN, if any, in cultured primary rat neuron and N2a NB cells. Our results indicated that CVN (only at 25 mg/L) treatment led to an increase in the total antioxidant capacity levels in cultured primary rat neuron cells compared with control cells. Also, CVN (at concentrations higher than 100 mg/L) treatment led to an increase in the total oxidative stress levels in both cell types. The mean values of the total scores of cells showing DNA damage (for comet assay) were not found to be significantly different from the control values in both cells (p > 0.05). On the other hand, after 24 h treatment with CVN, 3-(4,5-dimethylthiazol-2-yl)-2,5 diphenyltetrazolium bromide assay showed that CVN application significantly reduced the cell viability rates in both cell types at concentrations higher than 100 mg/L. Summarizing, our data suggest that CVN represents little potential for promising anticancer agent to improve brain tumors therapy.