Miracle-dz/UniFAR-FTUs huggingface dataset:
Inter-organisational knowledge sharing in regional sustainable development communities

There has been an increasing interest in the use of inter-organisational groups to address regional implications in sustainable development. These groups bring together local knowledge and expertise and span boundaries between government and industry organisations. Our focus is in understanding how knowledge is shared in such inter-organisational groups. Utilising interviews, observations and social network analysis, we examine the knowledge sharing implications derived from the mixed membership, multilevel interaction, and the need to span boundaries with external organisations in these collaborations.
Psychometric properties of Bengali version of QOLIE-10 in epileptic patients

Assessment of Quality of Life in Epilepsy has currently been emphasized to provide comprehensive care to patients. Aim: To develop and standardize and assess the psychometric properties of Bengali version of QOLIE-10 and to assess the relationship of quality of life with seizure variables and presence of psychiatric morbidity. Design: English QOLIE-10 was translated into Bengali by a translation committee using translation-re-translation technique. Inter-rater reliability between the English and Bengali version was assessed during initial practice session held amongst 20 bilingual patients. It was found that item 3 (related to driving) was reported to have difficulty in answering by all the patients as none drove any vehicle. Thus, this item was dropped. The inter-rater reliability of the resultant 9 item scale was found to be high (kappa = 0.9). One hundred and seven epilepsy patients attending the Epilepsy clinic were selected for the study if they met the following criteria: age >15 years, duration of seizure >1 year, regular intake of antiepileptic drugs, presence of informant and ability to read Bengali. For each patient, demographic and clinical data (seizure frequency, last seizure date, seizure type as per record, medicine intake history and records of past investigations such as EEG) was collected. Each patient were administered QOLIE-9 (Bengali) and SRQ-24 Bengali version to screen for psychiatric morbidity. Results: The Cronbach's Alpha coefficient for QOLIE-9 was 0.81, which did not improve if any item was dropped. All items showed strong correlation with the total score. The instrument showed stable factor structure with three factors (Limitation, Depression, Illness effects). However, the item with regard to memory problem did not fit into any of the factors. The QOLIE-9 total showed a significant correlation with the seizure frequency (r = 0.76**). SRQ positive (i.e., suspected psychiatric morbidity) cases had higher QOLIE-9 score (thus, poorer quality of life) in comparison to non-psychiatric cases. Conclusion: Bengali QOLIE-9 is a valid and reliable instrument to assess the quality of life in patients suffering from epilepsy.
Promoting Resilience and Psychological Well-Being in Vulnerable Life Stages

vices, even in high-income countries [16] ; t he majority of young people with mental health problems are still not getting the help they need. A major reason for this is the worldwide gaps in child and adolescent mental health policy and services well identified by the World Health Organization through its Atlas project [17] . T he degree of coverage and quality of mental health services for the youths are generally worse compared with the ones pro-vided for adults [18] . Little information is now available about health and social investment into child and ad-olescent mental well-being. However, as denounced in the Florence Declaration – developed during the 13thEuropean Society for Child and Adolescent Psychiatry (ESCAP) Congress and signed by WHO and by EACAP (European Academy for Child and Adolescent Psychia-try) – as regards Europe, all indicators strongly suggest that child and adolescent mental health in most countries is receiving a relatively small proportion of funding, with, in turn, a typically low investment for general health, on average only 5.6% (see appendix). The median percentage of governments’ health budget earmarked for mental health is as little as 1% in low income countries [19] T . he gap is not limited to the quantity, as the quality of ser-vices is often extremely poor, even in high income coun-tries [19] . Nevertheless, the mental well-being of children still remains a major public health priority and a prominent area of international debate. Scientists and researchers from all over the world are focusing on how to improve Mental health and emotional and psychological well-being are fundamental for all children, enabling them to meet their potential, to experience life as meaningful and to be active citizens. Unfortunately, current estimates indicate that at least one out of every four to five young people in the general population will suffer from at least one mental disorder in any given year [1] . Similar data have been previously reported by WHO, showing that worldwide up to 20% of children and adolescents suffer from a mental illness with at least mild functional impairment: one adolescent in five has behavioural, cognitive and emotional difficul-ties and one adolescent in eight suffers from a mental dis-order [2]. C omorbidity is very common and can occur at three levels: with other mental disorders, with substance abuse and with chronic diseases [1] . Developmental psychiatric disorders rarely have a spontaneous remission and may cause difficulties in so-cial adaptation or mental disorders in adult life [3–12] . There is evidence that adult mental disorders usually be-gin during youth [13, 14] , although they are often first detected later in life [1] . Besides personal suffering, stigma and discrimina-tion, mental disorders may have a high social impact, in terms of treatment and support costs, reduced or lost pro-ductivity, and the expenditure of criminal justice (e.g. conduct and behavioural disorders) [15] . De spite these data, only a minority of vulnerable chil-dren and adolescents have access to mental health ser-
THE REDSHIFT EVOLUTION OF THE MEAN TEMPERATURE, PRESSURE, AND ENTROPY PROFILES IN 80 SPT-SELECTED GALAXY CLUSTERS

We present the results of an X-ray analysis of 80 galaxy clusters selected in the 2500 deg2 South Pole Telescope survey and observed with the Chandra X-ray Observatory. We divide the full sample into subsamples of ∼20 clusters based on redshift and central density, performing a joint X-ray spectral fit to all clusters in a subsample simultaneously, assuming self-similarity of the temperature profile. This approach allows us to constrain the shape of the temperature profile over 0 < r < 1.5R500, which would be impossible on a per-cluster basis, since the observations of individual clusters have, on average, 2000 X-ray counts. The results presented here represent the first constraints on the evolution of the average temperature profile from z = 0 to z = 1.2. We find that high-z (0.6 < z < 1.2) clusters are slightly (∼30%) cooler both in the inner (r < 0.1R500) and outer (r > R500) regions than their low-z (0.3 < z < 0.6) counterparts. Combining the average temperature profile with measured gas density profiles from our earlier work, we infer the average pressure and entropy profiles for each subsample. Confirming earlier results from this data set, we find an absence of strong cool cores at high z, manifested in this analysis as a significantly lower observed pressure in the central 0.1R500 of the high-z cool-core subset of clusters compared to the low-z cool-core subset. Overall, our observed pressure profiles agree well with earlier lower-redshift measurements, suggesting minimal redshift evolution in the pressure profile outside of the core. We find no measurable redshift evolution in the entropy profile at r ≲ 0.7R500—this may reflect a long-standing balance between cooling and feedback over long timescales and large physical scales. We observe a slight flattening of the entropy profile at r ≳ R500 in our high-z subsample. This flattening is consistent with a temperature bias due to the enhanced (∼3×) rate at which group-mass (∼2 keV) halos, which would go undetected at our survey depth, are accreting onto the cluster at z ∼ 1. This work demonstrates a powerful method for inferring spatially resolved cluster properties in the case where individual cluster signal-to-noise is low, but the number of observed clusters is high.
Wimmer’s concept of psychogenic psychosis revisited

In the early twentieth century the Danish psychiatrist August Wimmer (1872—1937) developed the concept of psychogenic psychosis (PP) as a category of mental disorders separate from schizophrenia and manic depression. It subsumed a variety of clinical conditions with affective, confusional and paranoid features typically triggered by a psychical trauma. Wimmer’s work has established itself as one of the classic texts in Scandinavian psychiatry but, for linguistic reasons, long remained almost unknown in other European countries. Translated into English in 2003, it is now available for historical and psychopathological analyses. This paper describes the original meaning of PP and sets it in context, then discusses the implications arising from the usage of the diagnostic categories introduced to replace PP in modern international classifications.
Ethanol Damage to Canine Oxyntic Glandular Mucosa.∗

Summary The effect of ethanol upon the barrier function of the stomach was studied by irrigating pouches of the canine oxyntic glandular mucosa with solutions of ethanol ranging from 0.5 to 27% w/v. Solutions of 8% or less did not damage the mucosal barrier as judged by the fluxes of Na+, K+ and H+. Solutions of 14 and 27% broke the barrier, for fluxes of the ions across the mucosa were greatly increased during and following ethanol application. In contrast to acetylsalicylic acid which is much more damaging in acid than in neutral solution, ethanol has essentially the same effect upon the barrier when applied in 100 mM HCl or in 30 mM phosphate buffer, pH 7.5. The rate of absorption of ethanol is a linear function of its concentration. The damaging effect of ethanol depends upon the concentration in contact with the mucosa and not upon the quantity absorbed. Low concentrations of ethanol (8% or less) stimulate acid secretion. Histamine could not be detected in the arterial or gastric venous blood of anesthetized dogs when the stomach was filled with 8 or 14% ethanol.
New Surface-Associated Heat-Labile Colonization Factor Antigen (CFA/II) Produced by Enterotoxigenic Escherichia coli of Serogroups O6 and O8

Enterotoxigenic Escherichia coli (ETEC) belonging to serogroups O6 and O8 do not possess the H-10407-type colonization factor antigen (CFA/I). However, these frequently isolated ETEC were found to possess a second and distinct heat-labile surface-associated colonization factor antigen, termed CFA/II. Whereas CFA/I mediates mannose-resistant hemagglutination of human group A erythrocytes, CFA/II does not. CFA/II mediates mannose-resistant hemagglutination of bovine erythrocytes, and mannose-resistant hemagglutination is rapid only at reduced temperature (4°C). Because CFA/II, like CFA/I, is spontaneously lost by many ETEC isolates in the laboratory, it was possible to produce specific anti-CFA/II serum by preparing antiserum against living cells of a prototype strain (PB-176) and adsorbing this serum with living and heat-treated cells of its CFA/II-negative derivative strain PB-176-P. This serum, which neutralized the colonization factor activity of CFA/II-positive strains in infant rabbits, was employed to confirm the presence of CFA/II on ETEC which exhibited mannose-resistant hemagglutination of bovine but not human erythrocytes. CFA/II, like CFA/I, mediates adherence of the bacteria to the mucosal surface of the small intestine, as demonstrated by indirect immunofluorescence. CFA/II appears to be an important virulence factor for humans since CFA/II-positive ETEC are frequently isolated from diarrhea cases, particularly travelers' diarrhea, in Mexico; these ETEC were not uncommon in a collection of isolates from Bangladesh. The O6:H16 strain of ETEC responsible for an outbreak of diarrhea in the United States was also shown to be CFA/II positive. CFA/I and CFA/II were never found on the same serotypes of ETEC, but 98% of the heat-stable and heat-labile enterotoxin-producing ETEC belonging to the frequently isolated serogroups O6, O8, O15, O25, O63, and O78 were positive for either CFA/I or CFA/II.
Diagnosis and Prevalence of Leptospira Infection in Aborted and Stillborn Horses

A study was conducted to evaluate a recently available fluorescent antibody test (FAT) conjugate for the detection of leptospires in tissues of aborted and stillborn horses, to determine the leptospira antibody titers and compare serologic test results with FAT results, and to determine the prevalence of leptospira-induced abortions and stillbirths in the equine population of central Kentucky. From July 1, 1988 through June 30, 1989, 15 (2.5%) of 594 submissions (fetuses, stillborn foals, and/or placentas) were diagnosed as leptospirosis by the FAT (14 of 15 tested) and/or microscopic agglutination test (12 of 14 tested). Of the 12 serologically positive fetal fluids, 10 had high tigers against Leptospira interrogans serovar pomona and 2 against serovar grippotyphosa.
NEURONAL DEGENERATION IN LOCUS CERULEUS AND CORTICAL CORRELATES OF ALZHEIMER DISEASE

Abstract.Relationships were examined between neuronal degeneration in the nucleus locus ceruleus (nLC), a parameter of central noradrenergic impairment, and neocortical markers of Alzheimer disease (AD). The loss of nLC neurons was found to correlate significantly with norepinephrine concentration, choline acetyltransferase (ChAT) activity, and numbers of plaques and tangles in Brodmann area 24 (cingulate); ChAT and plaque counts in area 21 (temporal); and with ChAT activity in area 10 (frontal). In addition, nLC neuronal counts were correlated significantly with the severity and estimated duration of dementia. The number of neurofibrillary tangles in nLC, which did not correlate significantly with neocortical markers of AD, correlated with the estimated duration and severity of dementia. These data suggest that changes in central noradrenergic pathways are related to the pathophysiology of AD.
Extremely rapid recovery of human cone circulating current at the extinction of bleaching exposures

We used a conductive fibre electrode placed in the lower conjunctival sac to record the a‐wave of the human photopic electroretinogram elicited by bright white flashes, delivered during, or at different times after, exposure of the eye to bright white illumination that bleached a large fraction (∼90%) of the cone photopigment. During steady‐state exposures of this intensity, the amplitude of the bright‐flash response declined to ∼50% of its dark‐adapted level. After the intense background was turned off, the amplitude of the bright‐flash response recovered substantially, for flashes presented within 20 ms of background extinction, and fully, for flashes presented 100 ms after extinction. In addition, a prominent ‘background‐off a‐wave’ was observed, beginning within 5–10 ms of background extinction. We interpret these results to show, firstly, that human cones are able to preserve around half of their circulating current during steady‐state illumination that bleaches 90% of their pigment and, secondly, that following extinction of such illumination, the cone circulating current is restored within a few tens of milliseconds. This behaviour is in stark contrast to that in human rods, where the circulating current is obliterated by a background that bleaches only a few percent of the pigment, and where full recovery following a large bleach takes at least 20 min, some 50 000 times more slowly than shown here for human cones.
Palate Morphology in Children with Cleft Palate with Palatalized Articulation

This study was designed to examine postoperatively morphological characteristics of the palate of children with cleft palate with palatalized articulation. Palate morphology was measured in children with good velopharyngeal closure function after surgery, who were classified in Hellman's Dental Age II A group with unilateral cleft lip and palate, and the groups of children with palatalized articulation (CP-P) and normal articulation (CP-N) were compared. The results showed that the group of children with palatalized articulation was characterized by small palatal volume. In particular, there was narrowing and shortening of the anterior palate, and the palate was shallow. It was surmised that morphology may be one cause of palatalized articulation. Accordingly, it is important that early tongue-clicking movements are encouraged in patients exhibiting narrow palate morphology.
Propensity score analysis of vascular complications after diagnostic cardiac catheterization and percutaneous coronary intervention using thrombin hemostatic patch-facilitated manual compression.

OBJECTIVES To evaluate the adjusted risk of vascular complications after thrombin hemostasis patch-facilitated manual compression (THP-MC) for femoral artery access site management. BACKGROUND Thrombin hemostatic patches shorten time to hemostasis after cardiac procedures involving femoral artery access, but whether these patches are as safe as manual compression remains uncertain. METHODS THP-MC (D-Stat Dry, Vascular Solutions, Minneapolis, Minnesota) was used in 3,464 consecutive patients including 2,464 diagnostic cardiac catheterizations (CATH) and 1,000 percutaneous coronary intervention procedures (PCI) performed via a femoral access at a single site (WFUBMC). A total of 4,371 procedures including 2,956 CATH and 1,415 PCI performed prior to use of THP-MC, and treated with manual compression, served as the control group. Ambulation was permitted 2 to 3 hours after THP-MC, and 3 to 8 hours after MC. Propensity to receive a THP was calculated, and adjusted in-hospital outcomes evaluated. RESULTS Time to hemostasis was similar for THP-MC (13.0 +/- 3.3 min) compared to MC (14.4 +/- 5.7 min), p = 0.51 for CATH, and was shorter for THP-MC (14.2 +/- 5.4 minutes) compared to MC (20.1 +/- 5.4 min), p <0.001, for PCI. Overall, the unadjusted incidence of any vascular complication (VC) was 0.6+/- for THP-MC and 1.0% for manual compression, p = 0.036. The propensity score-adjusted odds ratio for any VC comparing THP-MC to manual compression was 0.58 (0.34 to 0.99) for all procedures, 0.42 (0.20 to 0.87) for diagnostic procedures and 0.86 (0.39 to 1.88) for PCI. CONCLUSIONS In this large, single-center, contemporary observational study, use of THP-MC shortened manual compression time for PCI procedures, permitted early ambulation and was as safe as conventional manual compression.
FlexFET: a low-cost planar, self-aligned independent-double-gate MOSFET with flexible, dynamic threshold control

A variety of double-gate (DG) MOSFET transistor structures are being developed to permit scaling to the sub-50nm regime. However, flexible dynamic threshold voltage control is urgently needed for ultra-low-power digital circuits, novel analog/RF circuits, and dynamically reconfigurable & self-repairing circuits (Yang et al., 1997). Independently-double-gated (IDG) FinFETs have recently been reported to have highly-controllable V/sub t/ without the use of multiple masks & implants (Liu et al., 2003; Liu et al., 2004; Fried et al., 2003). However, a lithographically-defined fin width of >10nm is required to achieve /spl Delta/V/sub t/=0.8V/V. The few recently reported planar IDG MOSFETs have oversized, nonself-aligned bottom gates and/or require epitaxial channel growth (Tanaka et al., 1991; Harrison et al., 2003; Guarini et al., 2001). We introduce FlexFET, a low-cost planar IDG MOSFET, with a damascene metal topgate and an implanted JFET bottomgate that are self-aligned in a gate trench. This new device is highly scalable, due to its sub-lithographic undoped channel, nonimplanted ultrashallow SDEs, nonepi raised SD's, and "gate-last" flow. Most damascene gate processes use a dummy gate and implanted SDE junctions. FlexFET utilizes a spacer-lined gate trench (Chen et al., 2000; Matsuo et al., 2002) that is etched through implanted SD regions to self-align its implanted JFET bottomgate with its TiN topgate. The top and bottomgates are connected at opposite edges of the device by a damascene local interconnect (LI) that is embedded in the STI regions between devices, resulting in high layout density. Since the top gate is CMPed, and the SDEs are not implanted, there is no damage to the channel edges. Effectively "raised" SDs are achieved without using selective epi. Sidewall spacers narrow the gate trench opening, resulting in >180nm channel lengths, even with low-cost relaxed 350nm lithography.
Oral Endocrine Therapy Nonadherence, Adverse Effects, Decisional Support, and Decisional Needs in Women With Breast Cancer

Background: Oral endocrine therapy (OET) such as tamoxifen or aromatase inhibitors reduces recurrence and mortality for the 75% of breast cancer survivors (BCSs) with a diagnosis of estrogen receptor–positive breast cancer. Because many BCSs decide not take OET as recommended because of adverse effects, understanding BCSs’ decisional supports and needs is foundational to supporting quality OET decision making about whether to adhere to OET. Objective: The aim of this study was to examine literature pertaining to OET nonadherence and adverse effects using the Ottawa Decision Support Framework categories of decisional supports and decisional needs because these factors potentially influence OET use. Methods: A systematic literature search was performed in PubMed and CINAHL using combined search terms “aromatase inhibitors and adherence” and “tamoxifen and adherence. ” Studies that did not meet criteria were excluded. Relevant data from 25 publications were extracted into tables and reviewed by 2 authors. Results: Findings identified the impact of adverse effects on OET nonadherence, an absence of decisional supports provided to or available for BCSs who are experiencing OET adverse effects, and the likelihood of unmet decisional needs related to OET. Conclusions: Adverse effects contribute to BCSs decisions to stop OET, yet there has been little investigation of the process through which that occurs. This review serves as a call to action for providers to provide support to BCSs experiencing OET adverse effects and facing decisions related to nonadherence. Implications for Practice: Findings suggest BCSs prescribed OET have unmet decisional needs, and more decisional supports are needed for BCSs experiencing OET adverse effects.
Specific cutaneous infiltrates of B‐cell chronic lymphocytic leukemia (B‐CLL) at sites typical for Borrelia burgdorferi infection

Background: Cutaneous manifestations of B‐cell chronic lymphocytic leukemia (B‐CLL) comprise a wide spectrum of clinicopathologic presentations. In some cases, onset of skin lesions is triggered by antigenic stimulation, and specific skin infiltrates at sites of previous herpes simplex or herpes zoster infection have been well documented. Specific skin manifestations of B‐CLL can also be observed at sites typical for lymphadenosis benigna cutis (nipple, scrotum, earlobe), a Borrelia burgdorferi‐associated cutaneous B‐cell pseudolymphoma.