Miracle-dz/UniFAR-FTUs huggingface dataset:
Gesture Use by Chimpanzees (Pan troglodytes): Differences Between Sexes in Inter‐ and Intra‐Sexual Interactions

Communication and social relationships are two of the most important aspects of primate life, but few studies have focused on linking these aspects in apes. There are some shared social pressures between the two sexes (e.g., kin selection, alliance formation, and protection against attack), but there are also differences (e.g., mate selection, dispersal, and social ranking systems). The aim of this study was to identify the communication strategies of the sexes with respect to their particular communication partner. I hypothesized the sexes use different strategies in their gestural communication based on their different social pressures. Specifically, males should have more positive intra‐sexual relationships than females because of high focus on male–male alliance formation and maintaining high social rank, both of which directly affect their mating opportunities and relationships with all other members of the group. On the other hand, females should have more positive inter‐sexual relationships due to the abuse they could receive from insubordination to males and because there is less focus on maintaining multiple, positive relationships with other females. Furthermore, because of differences in social pressures, males should have higher incidence of reassurance in same‐sex interactions than females because it should be more important for males to mitigate negative interactions. I analyzed the characteristics of the gesture repertoire and frequency of gesture use for each sex in each of four contexts: (1) aggression, (2) submission, (3) greeting, and (4) reassurance. I looked at intra‐sexual and inter‐sexual interactions, separately. I found that, indeed, males and females utilize different strategies of gestural communication. I also found that females, but not males, have a distinct gesture strategy for communicating with the opposite sex than for the same sex. This study shows there are distinct strategies utilized by the two sexes and these differences may be explained by their differing social pressures. Am. J. Primatol. 75:555‐567, 2013. © 2013 Wiley Periodicals, Inc.
A common system controls the induction of very different genes. The class-A beta-lactamase of Proteus vulgaris and the enterobacterial class-C beta-lactamase.

Among the Enterobacteriaceae, Proteus vulgaris is exceptional in the inducible production of a 29-kDa beta-lactamase (cefuroximase) with an unusually high activity towards the beta-lactamase-stable oximino-cephalosporins (e.g. cefuroxime and cefotaxime). Sequencing of the corresponding gene, cumA, showed that the derived CumA beta-lactamase belonged to the molecular class A. The structural gene was under the direct control of gene cumR, which was transcribed backwards and whose initiation codon was 165 bp away from that of the beta-lactamase gene. This resembled the arrangement of structural and regulator genes ampC and ampR of the 39-kDa molecular-class-C beta-lactamase AmpC present in many enterobacteria. Moreover, cloned genes ampD and ampG for negative modulation and signal transduction of AmpC beta-lactamase induction, respectively, were also able to restore constitutively CumA overproducing and non-inducible P. vulgaris mutants to the inducible, wild-type phenotype. The results indicate that controls of the induction phenomena are equivalent for the CumA and AmpC beta-lactamase. Very different structural genes can thus be under the control of identical systems.
Identification and partial characterization of Mycobacterium avium and Mycobacterium intracellulare by using DNA probes

We attempted to identify the Mycobacterium avium complex (MAC) isolated in Japan by using DNA probes specific for M. avium or Mycobacterium intracellulare (Gen-Probe Rapid Diagnostic System for MAC; Gen-Probe, Inc., San Diego, Calif.). The source and drug susceptibility distributions were examined. This assay system proved to be rapid, sensitive, specific, and reliable for identification of MAC and of the species as either M. avium or M. intracellulare. The DNA probe test showed that of the generally accepted MAC serovars, serovars 1 to 6, 8 to 11, and 21 belonged to M. avium and 7 and 12 to 20 belonged to M. intracellulare. Moreover, with the DNA probe test we found that the distribution patterns of M. avium and M. intracellulare isolates in Japan differed depending on the district in which MAC was isolated. The ratio of M. avium was much higher in eastern Japan. In Tokai and Shimane districts, the ratio of M. avium and M. intracellulare isolates significant in human disease was related to that of isolates from soil and house dust (natural sources). In M. avium, human disease-associated isolates were more resistant to rifampin, streptomycin, and kanamycin than were isolates from natural sources. However, this source dependence was not evident for M. intracellulare. In human disease-associated MAC, M. avium isolates were more resistant to most agents, except for quinolones, than were M. intracellulare isolates.
Free Anterolateral Thigh Flap for Reconstruction of Major Craniofacial Defects

Free-tissue transfer has revolutionized skull-base surgery by expanding the ability to perform cranial base resection and by improving the quality of reconstruction. The anterolateral thigh flap has come recently into use in the field of head and neck reconstruction. Its role in craniofacial and midface reconstruction has not been specifically defined. This study involved a total of 18 patients who were treated over a 5-year period from 1998 to 2003. Seventeen patients had locally advanced head and neck cancer, requiring craniofacial resection, and one patient had a complicated gun shot wound of the forehead. Thirteen patients were treated at the National Cancer Institute, Cairo University, Egypt, and five patients at the University of Miami, Florida. The patients presented with defects of the anterior skull base (5), lateral skull base (3), scalp and calvarium (3), and the midface (7). The anterolateral thigh flap was used as a myocutaneous flap in 11 cases and as a perforator fasciocutaneous flap in seven cases. Musculocutaneous perforators supplied the majority of flaps (17/18). Total flap survival occurred in 17 cases; one patient developed complete flap necrosis. The most commonly used recipient vessels were the facial vessels and the external jugular vein. Major complications included one case with meningitis; the patient died after failure of treatment. Another patient died 6 weeks postoperatively from pulmonary embolism. One patient developed CSF leak that stopped spontaneously. In addition, two patients developed minor wound dehiscence that healed spontaneously. The donor-site wound healed without problems except in two cases. One patient had an incomplete take of the skin graft; the other developed wound infection and superficial sloughing. Both wounds healed spontaneously. In addition to the feasibility of simultaneous flap harvesting with tumor resection, the flap's advantage in skull base reconstruction is its reliable blood supply, which can provide adequate dural cover and protection of the brain. Its size and moderate thickness are suitable for reconstruction of scalp and calvarial defects. The abundance of reliably vascularized fat in the flap may be an advantage in long-term maintenance of the volume of the flap in midface reconstruction. Similar to other soft tissue flaps, additional skeletal reconstruction may still be required to achieve an optimal functional and aesthetic result.
A Cluster of Suspected Cases of Zika Leading to Uncommon Dengue Serotypes with Possible Coexisting Zika Virus in Northern Thailand, 2016

Due to high morbidity and mortality since 1949, dengue is one of the notifiable diseases routinely reported to the Ministry of Public Health. On 10 Apr 2016, five people with fever and rash from a village in Phetchabun Province were notified. Descriptive, case-control, and environmental studies were conducted to verify diagnosis, describe characteristics of the outbreak, and determine risk factors. A confirmed case was a person with dengue-related symptoms, and dengue Immunoglobulin IgM, or dengue nucleic acids tested by reverse transcription polymerase chain reaction (RT-PCR). Controls were those without any symptoms and were randomly selected in the village. Of 12 dengue confirmed cases, there were six with DEN-3 and two with DEN-4 viruses. Living near cases (odds ratio = 11.1, 95% CI = 1.2, 98.3) and using home for community services (odds ratio = 9.2, 95% CI = 1.1, 79.6) were associated with dengue infection. One Aedes aegypti mosquito was identified with Zika virus by RT-PCR. A dengue outbreak related to serotypes DEN-3 and DEN-4 was confirmed with potential coexisting Zika virus in the village. Intensive vector control, elimination of mosquito breeding sites and health education provided in align with community participation controlled the outbreak.
Homogeneous processing in the striatal direct and indirect pathways: single body part sensitive type IIb neurons may express either dopamine receptor D1 or D2

Striatal medium spiny projection neurons (MSNs) output through two diverging circuits, the ‘direct and indirect pathways’ which originate from minimally overlapping populations of MSNs expressing either the dopamine receptor D1 or the dopamine receptor D2. One modern theory of direct and indirect pathway function proposes that activation of direct pathway MSNs facilitates output of desired motor programs, while activation of indirect pathway MSNs inhibits competing motor programs. A separate theory suggests that coordinated timing or synchrony of the direct and indirect pathways is critical for the execution of refined movements. These hypotheses are made testable by a common type of striatal neuron known as type IIb MSNs. Clusters of these MSNs exhibit phasic increases in firing rate related to sensorimotor activity of single body parts. If these MSNs were to reside in only the direct pathway, evidence would be provided that D1 MSNs are ‘motor program’ specific, which would lend credence to the ‘competing motor programs’ hypothesis. However, if type IIb MSNs reside in both pathways, evidence would be provided for the ‘coordinated timing or synchrony’ hypothesis. Our results show that type IIb neurons may express either D1 or D2. This evidence supports the theory that the coordinated timing or synchrony of the direct and indirect pathways is critical for refined movements. We also propose a model in which the direct and indirect pathways act as a differentiator circuit, providing a possible mechanism by which coordinated activity of D1 and D2 neurons may output meaningful somatosensorimotor information to downstream structures.
What educational resources are medical students using for personal study during primary care attachments?

INTRODUCTION Today's medical students have grown up in a technological world, with access to a wide variety of educational resources for their personal study. Although there is some evidence from the USA that students prefer the internet to textbooks, there is little evidence of UK students' preferences, particularly during their primary care attachments. AIMS To identify what educational resources medical students are using for their personal study during primary care attachments and why they make these choices. METHODS We held two focus groups, one with five, and one with seven fifth-year UK medical students after their primary care attachment. We analysed the transcripts using thematic analysis to identify the educational resources used, and identified themes to describe why the students made these choices. RESULTS Textbooks remain students' resource of choice for personal study. The most popular textbook was The Oxford Handbook of Clinical Medicine and internet sites were Google and GP Notebook. The choice of resource was influenced by convenience, purpose, recommendation, exam focus, reliability and learning styles. Two further overarching themes influencing their choices were the broad nature of general practice and the use of GP tutors as an important learning resource. DISCUSSION In contrast to the USA, textbooks remain the most popular resource for these UK students. Students felt that the style of learning within general practice was fundamentally different to other specialities due to the breadth of the subject matter and this influenced the resources used. This research could help inform the development of educational resources tailored to the learners, and provides further evidence for the need to develop a more structured curriculum for students in primary care. Further research could explore the ideal role of GP tutors.
Developing the theoretical basis for service user/survivor-led research and equal involvement in research

Summary Aims and methods — This article, written from a service user/survivor perspective, explores a hypothesis which seeks to offer a more systematic basis for the full and equal involvement of mental health service users/survivors in both the research process and research structures more generally. The hypothesis challenges traditional emphasis on positivist assumptions about the priority of values of ‘distance’, ‘neutrality’ and ‘objectivity’ (which it argues discriminate against service users and their experiential knowledge). It explores instead the idea that ‘the shorter the distance between direct experience and its interpretation, then the less likely resulting knowledge is to be inaccurate, unreliable and distorted. Results and conclusions — The proposal discusses ways in which such (objective and subjective) distance may be reduced, to improve the quality of research, to enable more equal involvement of service users and their direct experience and to make it possible for non-service user researchers to work alongside service users on more equal terms. Declaration of Interest: Peter Beresford is Professor of Social Policy at Brunei University and Chair of Shaping Our Lives, the national independent user controlled organisation which receives its core funding from the UK Department of Health. No financial support from pharmaceutical or other commercial companies has been received by the author over the last two years. Funding has been gained from governmental and non-governmenatal funding agencies.
What Role Do Norms Play in Global Teamwork? The Influence of Cultural Communication and Coordination Norms on Team Processes in Internationally Distributed Teams

WHAT ROLE DO NORMS PLAY IN GLOBAL TEAMWORK? THE INFLUENCE OF CULTURAL COMMUNICATION AND COORDINATION NORMS ON TEAM PROCESSES IN INTERNATIONALLY DISTRIBUTED TEAMS Tine Koehler, Ph.D. George Mason University, 2009 Dissertation Director: Jose M. Cortina Internationally distributed teams (IDTs) face many challenges; however, there is a lack of research on what makes IDTs successful. In addition, research has yet to assess how IDTs develop and which team processes facilitate team functioning. Norms have played an important role in team development models of traditional, meaning collocated and homogenous, teams. The current study assesses the role of norms for team development in IDTs. More specifically, this study examines the effects of culture-driven communication and coordination norms on team interactions and on the creation of team norms which subsequently affect team processes such as cohesion, trust, motivation, and
Women's memory of childbirth at two months and one year after the birth.

BACKGROUND Studies of women's memory of labor and birth have generally concluded that women's recall is fairly accurate, but the findings are not unanimous. The aim of this study was to compare women's experiences of labor pain and overall experience of the birth at 2 months and 1 year after the delivery. METHODS A longitudinal cohort study of 2,428 women recruited in early pregnancy from all antenatal clinics in Sweden during 3 weeks evenly spread during 1999-2000 was conducted. In addition to a questionnaire in early pregnancy including background data, the women completed a questionnaire at 2 months and 1 year after the birth including the same 7-point rating scale of pain intensity and the same question about overall experience of labor and birth. RESULTS Forty-seven percent of the women made the same assessment of pain intensity, and 60 percent of childbirth overall, at 1 year as they did at 2 months after the birth. One year after the birth, 35 percent recalled pain as less severe, and 18 percent as more severe, and 24 percent said labor and birth overall was more negative, whereas 16 percent said it was more positive. CONCLUSION This study showed great variation in women's memories of labor and birth, and conclusions by some other studies, often based on analyses of group data rather than on the responses of the individual participants were, to some extent, challenged.
postoperative Infections of the Spine

I is one of the most common causes of morbidity in the acute phase following lumbar spine surgery. Wound infections of the spine can have devastating consequences on the outcome after procedures such as a simple discectomy or a multilevel decompression and instrumentation fusion. Once identified, rapid and definitive treatment offers the best hope for restoring the patient to the normal recovery process. Prevention is clearly better than treatment for this unfortunate complication, which continues to occur relatively frequently even in the presence of aseptic techniques and prophylactic antibiotic agents. As our surgery-related ability to manage more complex spinal disorders improves, the unfortunate potential for wound complications increases because these procedures often require prolonged operations and multisegmental internal fixation.
Robustness of the Carhart four-factor and the Fama-French three-factor models on the South African stock market

Purpose - – The purpose of this study is to explore the applicability of the Fama–French and Carhart models on the South African stock market (SASM). It examines the ability of the models to capture size, book-to-market (BM) and momentum effects on the SASM. The paper, additionally, explores the ability of the Fama–French–Carhart factors to predict the future growth of the South African economy. Design/methodology/approach - – The paper relies on data of 848 firms from January 1996 to April 2012 to examine the size, BM and momentum effects on the SASM. The paper constructs the test assets from a 3 × 3 sort on size and BM and a 3 × 3 sort on size and momentum. The paper estimates momentum as the past six-months’ cumulative return. The momentum portfolios are monthly rebalanced. Additionally, the size and BM portfolios are formed annually at the end of each June. Findings - – Evidence is provided that size, BM and momentum effects exist on the SASM; also, the small- and high-BM firm portfolios, respectively, appear riskier than the big- and low-BM firm portfolios. The paper provides evidence of past winners outperforming past losers aside from the small-firm group. Additionally, the models only partially capture the size and value effects on the SASM. The Carhart model partly captures the momentum effects, but the Fama–French model is unable to describe the returns to the momentum-sorted portfolios. The evidence shows that the models’ factors predict future gross domestic product growth. Originality/value - – The models do not fully describe returns on the SASM; any application of the models on the SASM should be done with caution. The Carhart model better describes returns than the Fama–French model on the SASM. The Fama–French–Carhart factors may relate to the underlying economic risk of the South African economy.
The E1B 19,000-molecular-weight protein of group C adenoviruses prevents tumor necrosis factor cytolysis of human cells but not of mouse cells

Tumor necrosis factor (TNF) is a multifunctional immunoregulatory protein that is secreted by activated macrophages and is believed to have antiviral activities. We reported earlier that when mouse C3HA fibroblasts are infected with human adenoviruses, the 289R and 243R proteins encoded by region E1A render the cells susceptible to lysis by TNF, and a 14,700-molecular-weight protein (14.7K protein) encoded by region E3 protects the cells against lysis by TNF. We now report that the 19,000-molecular-weight (19K) (176R) protein encoded by the E1B transcription unit can protect human HEL-299 fibroblasts and human ME-180 cervical carcinoma cells against lysis by TNF. This was determined by infecting cells with adenovirus double mutants that lack region E3 and do or do not express the E1B-19K protein and by measuring cytolysis by using a short-term (18-h) 51Cr-release assay. Under these assay conditions, the 51Cr release was specific to TNF and was not a consequence of the cyt phenotype associated with E1B-19K protein-negative mutants. Also, by using virus double mutants that lack E3 in combination with other early regions, we found that E1A, the E1B-55K protein-encoding gene, E3, and E4 are not required to protect HEL-299 cells against TNF cytolysis. Three additional human cancer cell lines (HeLa, HCT8, and RC29) and a simian virus 40-transformed WI38 cell line (VA-13) also required E1B for protection against TNF cytolysis, indicating that the E1B-19K protein is required to protect many if not all human cell types against lysis by TNF when infected by adenovirus. The E1B-19K protein was not able to protect six different adenovirus-infected mouse cell lines against TNF lysis, even though the protein was shown to be efficiently expressed in one of the cell lines. HEL-299 or ME-180 cells infected by a mutant that lacks the E1B-19K protein but retains region E3 were not lysed by TNF, indicating that one or more of the E3 proteins can protect these cells against TNF lysis in the absence of the E1B-19K protein. Thus, the E3-14.7K but not the E1B-19K protein can protect adenovirus-infected mouse cells against TNF cytolysis, whereas the E1B-19K protein as well as one or more of the E3 proteins can protect adenovirus-infected human cells against TNF cytolysis.
Macro-Finance Separation by Force of Habit

We incorporate risk premia variation arising from Campbell-Cochrane habit formation in a standard DSGE framework. We show how the simultaneous presence of consumption and labor habits can produce a separation between quantity and risk premia dynamics, and hence unite nonlinear habits and a production economy without compromising the ability of the model to fit macroeconomic variables. We can then use economic theory rather than a reduced-form approach to restrict several cashflow processes endogenously and study their pricing. First, nominal price rigidities explain an endogenous difference between aggregate consumption and market dividends and between real and nominal bonds that can rationalize two major asset pricing puzzles - an initially downward-sloping term structure of equity and an upward-sloping term structure of interest rates. Second, the model is able to explain the capital market's reaction to a monetary policy shock documented by the extant literature.