Miracle-dz/UniFAR-FTUs huggingface dataset:
Toward a Typology of Buyer-Supplier Relationships: A Study of the Computer Industry

Buyer–supplier relationship typologies are useful analytical tools for purchasing managers in managing exchange relationships with suppliers and monitoring their purchasing portfolios. Existing buyer–supplier relationship typologies are mainly focused on either relational contents or power-dependence and have limited empirical support for their performance implications. In this study, we developed an alternative buyer–supplier relationship typology that integrates both relational content and power-dependence dimensions, resulting in four generic relationship types: market, power, autonomous-link, and constrained-link relationships. We then performed a longitudinal exploratory investigation of eight leading firms in the U.S. computer industry to explore the performance implications of the typology, using a combinatorial qualitative approach that leverages the strengths of case study research, content analysis, and quasi-experimental design. The results suggest three theoretical propositions. First, the association between the type of buyer–supplier relationships and buyer firm performance varies such that constrained-link relationships are superior in terms of operational efficiency while autonomous-link relationships are superior in terms of product innovation. Second, the positive association between buyer–supplier relational contents (i.e., relationalism) and buyer firm operational efficiency is strengthened as the suppliers' dependence on the buyer firm increases. And finally, the positive association between buyer–supplier relationalism and buyer firm product innovation is weakened as the suppliers' dependence on the buyer firm increases.
Entorhinal cortex of the rat: Cytoarchitectonic subdivisions and the origin and distribution of cortical efferents

The origins and terminations of entorhinal cortical projections in the rat were analyzed in detail with retrograde and anterograde tracing techniques. Retrograde fluorescent tracers were injected in different portions of olfactory, medial frontal (infralimbic and prelimbic areas), lateral frontal (motor area), temporal (auditory), parietal (somatosensory), occipital (visual), cingulate, retrosplenial, insular, and perirhinal cortices. Anterograde tracer injections were placed in various parts of the rat entorhinal cortex to demonstrate the laminar and topographical distribution of the cortical projections of the entorhinal cortex. The retrograde experiments showed that each cortical area explored receives projections from a specific set of entorhinal neurons, limited in number and distribution. By far the most extensive entorhinal projection was directed to the perirhinal cortex. This projection, which arises from all layers, originates throughout the entorhinal cortex, although its major origin is from the more lateral and caudal parts of the entorhinal cortex. Projections to the medial frontal cortex and olfactory structures originate largely in layers II and III of much of the intermediate and medial portions of the entorhinal cortex, although a modest component arises from neurons in layer V of the more caudal parts of the entorhinal cortex. Neurons in layer V of an extremely laterally located strip of entorhinal cortex, positioned along the rhinal fissure, give rise to the projections to lateral frontal (motor), parietal (somatosensory), temporal (auditory), occipital (visual), anterior insular, and cingulate cortices. Neurons in layer V of the most caudal part of the entorhinal cortex originate projections to the retrosplenial cortex. The anterograde experiments confirmed these findings and showed that in general, the terminal fields of the entorhinal‐cortical projections were densest in layers I, II, and III, although particularly in the more densely innervated areas, labeling in layer V was also present. Comparably distributed, but much weaker projections reach the contralateral hemisphere. Our results show that in the rat, hippocampal output can reach widespread portions of the neocortex through a relay in a very restricted part of the entorhinal cortex. However, most of the hippocampal‐cortical connections will be mediated by way of entorhinal‐perirhinal‐cortical connections. We conclude that, in contrast to previous notions, the overall organization of the hippocampal‐cortical connectivity in the rat is largely comparable to that in the monkey. Hippocampus 7:146–183, 1997. © 1997 Wiley‐Liss, Inc.
The efficacy and safety of romiplostim in adult patients with chronic immune thrombocytopenia

Romiplostim is a thrombopoietin peptide mimetic agent recently approved for the treatment of adults with chronic immune thrombocytopenia (ITP). In randomized controlled studies, this agent has demonstrated an increase in the platelet count in the majority of patients with ITP, both in splenectomized and nonsplenectomized patients. In up to 5 years of follow up, its safety profile has been favorable, suggesting this could be a novel therapeutic agent in patients with ITP. This article summarizes the development of this new agent and explores its safety and efficacy in adults with chronic ITP.
Pinning control of scale-free complex networks

The pinning control strategy, including specifically pinning scheme and randomly pinning scheme, is used to stabilize scale-free networks in this paper. A scale-free dynamical network model is first introduced and then, based on this model, a stability condition is derived in terms of a linear matrix inequality. Finally, a numerical simulation example is provided to verify the theoretical results.
θ-Band and β-Band Neural Activity Reflects Independent Syllable Tracking and Comprehension of Time-Compressed Speech

Recent psychophysics data suggest that speech perception is not limited by the capacity of the auditory system to encode fast acoustic variations through neural γ activity, but rather by the time given to the brain to decode them. Whether the decoding process is bounded by the capacity of θ rhythm to follow syllabic rhythms in speech, or constrained by a more endogenous top-down mechanism, e.g., involving β activity, is unknown. We addressed the dynamics of auditory decoding in speech comprehension by challenging syllable tracking and speech decoding using comprehensible and incomprehensible time-compressed auditory sentences. We recorded EEGs in human participants and found that neural activity in both θ and γ ranges was sensitive to syllabic rate. Phase patterns of slow neural activity consistently followed the syllabic rate (4–14 Hz), even when this rate went beyond the classical θ range (4–8 Hz). The power of θ activity increased linearly with syllabic rate but showed no sensitivity to comprehension. Conversely, the power of β (14–21 Hz) activity was insensitive to the syllabic rate, yet reflected comprehension on a single-trial basis. We found different long-range dynamics for θ and β activity, with β activity building up in time while more contextual information becomes available. This is consistent with the roles of θ and β activity in stimulus-driven versus endogenous mechanisms. These data show that speech comprehension is constrained by concurrent stimulus-driven θ and low-γ activity, and by endogenous β activity, but not primarily by the capacity of θ activity to track the syllabic rhythm. SIGNIFICANCE STATEMENT Speech comprehension partly depends on the ability of the auditory cortex to track syllable boundaries with θ-range neural oscillations. The reason comprehension drops when speech is accelerated could hence be because θ oscillations can no longer follow the syllabic rate. Here, we presented subjects with comprehensible and incomprehensible accelerated speech, and show that neural phase patterns in the θ band consistently reflect the syllabic rate, even when speech becomes too fast to be intelligible. The drop in comprehension, however, is signaled by a significant decrease in the power of low-β oscillations (14–21 Hz). These data suggest that speech comprehension is not limited by the capacity of θ oscillations to adapt to syllabic rate, but by an endogenous decoding process.
Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis

Several lines of evidence have implicated matrix metalloproteinase 9 (MMP-9) as a protease inducing an angiogenic switch critical for tumor progression. Among MMP-9-expressing cell types, including cancer cells and tumor-associated leukocytes, inflammatory neutrophils appear to provide an important source of MMP-9 for tumor angiogenesis. However, delivery of MMP-9 by neutrophils has not been mechanistically linked to its catalytic activity at the angiogenic site. By using a modified angiogenic model, allowing for a direct analysis of exogenously added cells and their products in collagen onplants grafted on the chorioallantoic membrane of the chicken embryo, we demonstrate that intact human neutrophils and their granule contents are highly angiogenic. Furthermore, purified neutrophil MMP-9, isolated from the released granules as a zymogen (proMMP-9), constitutes a distinctly potent proangiogenic moiety inducing angiogenesis at subnanogram levels. The angiogenic response induced by neutrophil proMMP-9 required activation of the tissue inhibitor of metalloproteinases (TIMP)-free zymogen and the catalytic activity of the activated enzyme. That the high angiogenic potency of neutrophil proMMP-9 is associated with its unique TIMP-free status was confirmed when a generated and purified stoichiometric complex of neutrophil proMMP-9 with TIMP-1 failed to induce angiogenesis. Recombinant human proMMP-9, operationally free of TIMP-1, also induced angiogenesis at subnanomolar levels, but lost its proangiogenic potential when stoichiometrically complexed with TIMP-1. Similar proMMP-9/TIMP-1 complexes, but naturally produced by human monocytic U937 cells and HT-1080 fibrosarcoma cells, did not stimulate angiogenesis. These findings provide biochemical evidence that infiltrating neutrophils, in contrast to other cell types, deliver a potent proangiogenic moiety, i.e., the unencumbered TIMP-free MMP-9.
Cell Cycle Analysis of Epstein-Barr Virus-Infected Cells following Treatment with Lytic Cycle-Inducing Agents

ABSTRACT While Epstein-Barr virus (EBV) latency-associated gene expression is associated with cell cycle progression, the relationship between the EBV lytic program and the cell cycle is less clear. Using four different EBV lytic induction systems, we address the relationship between lytic cycle activation and the cell cycle. In three of these systems, G0 or G1 cell growth arrest signaling is observed prior to detection of the EBV immediate-early gene product Zta. In tetradecanoyl phorbol acetate-treated P3HR1 cultures and in 5-iodo-2′-deoxyuridine-treated NPC-KT cultures, cell cycle analysis of Zta-expressing cell populations showed a significant G1bias during the early stages of lytic cycle progression. In contrast, treatment of the cell line Akata with anti-immunoglobulin (Ig) results in rapid induction of immediate-early gene expression, and accordingly, activation of the immediate-early gene product Zta precedes significant anti-Ig-induced cell cycle effects. Nevertheless, cell cycle analysis of the Zta-expressing population following anti-Ig treatment shows a bias for cells in G1, indicating that anti-Ig-mediated induction of Zta occurs more efficiently in cells traversing G1. Last, although 5-azacytidine treatment of Rael cells results in a G1 arrest in the total cell population which precedes the induction of Zta, cell cycle analysis of the Zta-expressing population shows a significant bias for cells with an apparent G2/M DNA content. This bias may result, in part, from activation of Zta expression following demethylation of the Zta promoter during S-phase. Together, these studies indicate that induction of Zta occurs through several distinct mechanisms, some of which may involve checkpoint signaling.
Personality, coping style and well-being of parents rearing children with developmental disabilities.

BACKGROUND Parents with children with developmental disabilities (DD) encounter a variety of stressors associated with rearing their children and must develop effective coping mechanisms in order to adapt successfully to these challenges. Previous research has failed to establish the role of parental individual differences in the reported use of different coping strategies. The current study explores parental personality and whether children with DD were adopted or born into the families and their influence on the coping strategies used by mothers and fathers. METHODS A total of 97 mother-father dyads rearing at least one child with DD were participants. They narrated stressful situations related to their child and completed the Ways of Coping Questionnaire twice. Data were also collected with regard to personality, depression and subjective well-being (SWB). RESULTS Both adoptive and birth mothers and fathers used more problem-focused than emotion-focused strategies. Personality factors, Neuroticism especially, were predictive of coping strategy use. Higher levels of Positive Reappraisal were associated with higher levels of SWB, whereas higher levels of Escape-Avoidance were associated with lower levels of SWB, but only for mothers. Results were consistent with a dispositional model of strategy use in that frequency of use was associated with personality characteristics, was consistent over time, and for different children in the same families. Future research should focus on the persistence of the associations between strategy use and well-being and whether they hold true at different stages of the lifespan when coping contexts may change quite dramatically.
Hard Time Parsing Questions: Building a QuestionBank for French

We present the French Question Bank, a treebank of 2600 questions. We show that classical parsing model performance drop while the inclusion of this data set is highly beneficial without harming the parsing of non-question data. when facing out-of- domain data with strong structural diver- gences. Two thirds being aligned with the QB (Judge et al., 2006) and being freely available, this treebank will prove useful to build robust NLP systems.
SALT IODIZATION AND THE ENFRANCHISEMENT OF THE AMERICAN WORKER

In 1924, The Morton Salt Company, the largest salt producer in the United States, began nationwide distribution of iodine-fortified salt. Access to iodine, a key determinant of cognitive ability, rose considerably, leading to increased intelligence quotients particularly in previously iodine-deficient areas. We compare economic outcomes for cohorts exposed in utero to iodized salt with those of slightly older, unexposed cohorts, across states with high versus low iodine deficiency rates prior to the advent of salt fortification. We estimate that labor force participation rose by 1.35 percentage points as a result of iodization. Analysis of income transitions by quintile shows that new labor force joiners entered at the bottom of the wage distribution, pulling down average wage income conditional on employment. Consistent with effects primarily on low-skilled, low-wage employment, we find little evidence of significant changes in high school completion rates. Results are driven by impacts on women: salt iodization can account for roughly 5 percent of the rise in female participation between 1950 and 1990. Our results inform the ongoing debate regarding micronutrient fortification campaigns in many low-income countries. We show that blanket iodized salt distribution in fact had a very targeted impact, benefiting those on the margin of employment and generating sizable economic returns at little public cost.
The Effect of Ownership Composition on Earnings Management: Evidence for the Mexican Stock Exchange

Purpose – This paper aims to examine the relationship between different types of shareholders that command share ownership, family, institutions or external blockholders and earnings management. In addition, it examines the effect of company size on earnings management. <br><br>Design/methodology/approach – The sample includes 67 companies listed in the Mexican Stock Exchange for the period 2005-2015. The sample composition is quite industry-balanced. A cross-sectional version of the Jones model (1991) is to measure the earnings management. The GMM (generalized method of moments) model is also estimated. <br><br>Findings – The results show that family and institutional ownership reduce the earnings management, but the impact is different depending on the company size. <br><br>Research limitations/implications – The results show that there is a clear relationship between increasing participation of family and institutional investors and a reduction in earnings management. This is consistent with the literature that establishes that ownership is an effective regulatory mechanism that limits earnings management through closer supervision and involvement in management. <br><br>Practical/implications – For companies’ corporate governance and regulatory authorities, the results of this study may serve to improve the decision-making. <br><br>Originality/value – This study shows that ownership structure can provide corporate governance in Mexican listed companies with different monitoring and control capacities to influence companies’ strategies, particularly in relation to the discretion of earnings management.
Associations between cigarette smoking, obesity, sociodemographic characteristics and remote-sensing-derived estimates of ambient PM2.5: results from a Canadian population-based survey

Objectives Long-term exposure to ambient fine particles (PM2.5) has been shown to increase mortality. Variables measured on the same spatial scales of air pollution may confound associations, and so the authors' objectives were to evaluate the associations between PM2.5 and individual-level measures of smoking, obesity and sociodemographic status. The authors present an approach to evaluate the impact that uncontrolled confounding from smoking may have on associations between PM2.5 and mortality. Methods Individual-level behavioural and sociodemographic data were obtained from a 2003 national survey of 122 548 Canadians. Estimates of ground-level PM2.5 at a resolution of 10×10 km between 2001 and 2006 were derived from satellite remote sensing. Exposures were assigned to the residence of the participants at the time of the survey. Differences in the prevalence of smoking across concentrations of PM2.5 and RRs drawn from the literature were used to model the bias on rate ratios. Results Participants in areas with higher concentrations of PM2.5 had a higher income and educational attainment, smoked less and were more likely immigrants. Smoking had a negative confounding effect on the associations between PM2.5 and mortality. To compensate for this bias, for a 10 μg/m3 increase in PM2.5, mortality from lung cancer and heart disease in the referent exposure group needed to be increased by 6.9% and 3.2%, respectively. Conclusions Associations were found between sociodemographic and lifestyle characteristics and PM2.5 at a resolution of 10×10 km. The authors present a model to adjust for uncontrolled confounding of smoking that can be readily adapted to exposures measured at different spatial resolutions.
QFSRD : Orthogenesis Evolution based Genetic Algorithm for Qos Fitness Scope aware Route Discovery in Ad Hoc Networks

Here in this paper we devised a novel orthogenesis evolution based GA technique for QoS fitness scope aware routing in Mobile Ad hoc Networks. The past decade research towards route discovery strategies for mobile ad hoc networks is continuing with magnitude speed. However, the majority of the routing solutions devised in past are dealing only with the optimality of the data transmission. QoS aware hop level connections in a given route are not supported with the desired frequency. Hence the QoS aware routing in mobile ad hoc networks is grabbing the attention of many researchers as this domain is on the hot edge of the current research. In regard to this we devised an Orthogenesis evolution based Genetic algorithm for QoS fitness scope aware route discovery in Mobile ad hoc networks. Due to the computational complexities of GA and limits of ad hoc network resources, very few researchers devised GA based QoS optimality strategies for route discovery in MANETs. The model devised here in this paper is successfully handling these issues and emerged as best in its class of QoS aware route discovery strategies. The experimental results are exploring the scalability, optimality and robustness of the proposed model.
Liver transplantation (2).

Rejet et histocompatibilite. Prevention du rejet. Recidive de la maladie (cancer, hepatite B, hepatite non-A-non-B, autres maladies recidivantes). Transplantation de plusieurs organes. Qualite de la vie. Transplantation auxiliaire. Financement et appels au public
An epidemiological study of enuresis among primary school children in Isfahan, Iran.

OBJECTIVE To estimate the prevalence of enuresis in primary school children in Iran and to determine the factors associated with this disorder. METHODS A cross-sectional time-ordered study was performed at the Faculty of Medicine, Isfahan Medical University, Isfahan, Iran from September 2005 to January 2006. A total of 4500 self-administered questionnaires were distributed to parents of children aged 6-12 years attending 30 primary schools. RESULTS From an overall response rate of 69.9%, enuresis was reported in 216 children (7%), comprising 6.2% for nocturnal enuresis according to ICD10 and 3.3% according to DSM IV, 0.5% for diurnal enuresis and 0.8% for combined day and night wetting. Primary nocturnal enuresis was reported in 166 children (5.3%). Seventy-one (50.7%) of the 140 children with nocturnal enuresis had > or =3 wet nights per week. A positive family history in father and mother was seen in 51% and 39% of children with primary nocturnal enuresis respectively. Using logistic regression analysis, younger age (p < 0.002), gender (p < 0.0001) and low level of education of mother (p < 0.028) were significant predictors of enuresis. Positive history of enuresis in father was a significant predictor of primary nocturnal enuresis (p < 0.012). CONCLUSION The prevalence of nocturnal enuresis in Iran is lower than those reported in western countries, however, higher percentage demonstrated severe enuresis. The prevalence of diurnal enuresis is lower than previous studies. Age, gender and the educational level of the mother are the main risk determinants of enuresis and the prevalence of primary nocturnal enuresis appears to be significantly related to positive history of enuresis in father.
The association between Helicobacter pylori gastritis and lymphoid aggregates, lymphoid follicles and intestinal metaplasia in gastric mucosa of children

The aim of the study was to determine the topographic prevalence of lymphoid follicles, lymphoid aggregates, gastric glandular atrophy and intestinal metaplasia among children with chronic abdominal pain. The association between these lesions and age, type of gastritis and Helicobacter pylori density was also assessed.