Miracle-dz/UniFAR-FTUs huggingface dataset:
Factors influencing the family consent rate for organ donation in the UK

The refusal rate for organ donation in the UK is 42%, among the highest in Europe. We extracted data on every family approach for donation in UK ICUs or Emergency Departments between 1st April 2012 and 30th September 2013, and performed multiple logistic regression to identify modifiable factors associated with consent. Complete data were available for 4703 of 4899 approaches during the study period. Consent for donation after brain death was 68.9%, and for donation after circulatory death 56.5% (p < 0.0001). Patient ethnicity, knowledge of a patient's wishes and involvement of a specialist nurse in organ donation in the approach were strongly associated with consent (p < 0.0001). The impact of the specialist nurse was stronger for donation after circulatory death than for donation after brain death, even after accounting for the impact of prior knowledge of patients' wishes. Involvement of the specialist nurse in the approach, encouraging family discussions about donation wishes and promotion of the organ donor register are key strategies to increase UK consent rates, and are supported by this study.
Targeting Potential Active Users for Mobile App Install Advertising: An Exploratory Study

ABSTRACT App install advertising not only serves as a revenue source for mobile app developers and mobile ad platforms, but also is considered an effective channel for app exposure to mobile app users. Owing to their benefits to the main players, such ads are the driving force of mobile advertising growth. For the purpose of improving the effectiveness of app install ads, this study investigated how to select potential active users for advertised apps based on users’ previous app usage behaviors. By analyzing large-scale field data on game app usage behaviors, users’ engagement level, specifically daily number of purchase activity in the medium app was found as the significant factor for targeting potential active users for the advertised app. However, users with a longer app session time in medium app and users who have more game apps in their mobile devices have a lower probability of becoming active users of the advertised app due to their limited time. It was also found that users who have played game apps in the same category as the advertised app are more likely to become active users of the advertised app. Both the theoretical and practical implications of the findings are discussed for improving the effectiveness of app install ads.
Genomics Hypoxia-Independent Gene Expression Mediated by SOX 9 Promotes Aggressive Pancreatic Tumor Biology

Pancreatic cancer aggressiveness is characterized by its high capacity for local invasion, ability to promote angiogenesis, and potential to metastasize. Hypoxia is known to represent a crucial step in the development of aggressive malignant features of many human cancers. However, micrometastatic tumors are not typically subjected to hypoxic events during early stages of dissemination; therefore, it is unclear how these tumors are able to maintain their aggressive phenotype. Thus, the identification of regulators of hypoxia-related genes in aggressive/ metastatic tumors represents a fundamental step for the design of future therapies to treat pancreatic cancer. To this end, transcriptomic profiles were compared between the nonmetastatic pancreatic cancer cell line FG (LMET) and its angiogenic/metastatic derivate L3.6pl (HMET) under normoxic or hypoxic conditions. Cluster analysis revealed a number of transcripts that were induced by hypoxia in nonmetastatic cancer cells. Strikingly, this cluster was determined to be constitutively activated under normoxia in the metastatic cancer cells and could not be further induced by hypoxia. A subset of these transcripts were regulated by the transcription factor SOX9 in the aggressivemetastatic cells, but driven by hypoxia-inducible factor-1a (HIF-1a) in the parental nonmetastatic cell line. Moreover, these transcripts were enriched in cancer-related networks including:WNT, CXCR4, retinoic acid, and (FAK) focal adhesion kinase, gene PTK2 signaling pathways. In functional assays, inhibition of SOX9 expression in HMET cells led to increased apoptosis and reduced migration in vitro and a significant reduction in primary tumor growth, angiogenesis, andmetastasis following orthotopic tumor cell injection. At themolecular level, the control of SOX9 expression was associated with changes in the methylation status of the SOX9 promoter. Finally, SOX9 upregulation was verified in a series of tumor specimens of patients with pancreatic carcinoma. Implications: SOX9 represents a novel target for pancreatic cancer therapy.Mol Cancer Res; 1–12. 2013 AACR.
A Pressor Response Associated with Drinking in Rats

Summary When angiotensin II is injected into the cerebral ventricles of the rat, drinking and a short latency pressor response are produced. We have found that the pressor response has two components. The first component is always associated with angiotensin injections. The second component, however, is associated with drinking behavior. If water is not available, the second pressor component is absent. We have investigated this drinking-associated pressor response and find that it is not only seen when angiotensin is the stimulus, but also in normal or carbachol-induced drinking. The effect is not due to head position during drinking or hypoxia but it is mediated by the sympathetic nervous system since it is abolished by alpha-adrenergic blockage. We are grateful for the technical assistance of Judy Phipps and to Dr. J. Farber for advice. This work was supported by Program Project Grant No. HI07007 to W. E. H. , NSF Grant No. BNS75-16364 to M. I. P. and Grant No. MRIS 7737.03 from the Veterans Administration to Phillip G. Schmid, M.D.
Reflecting on the "Dark Side" of Information Technology Use

The objective of this panel is to advance knowledge in areas related to the “dark” side of IT use in organizations. Emerging and as yet nascent academic research is beginning to focus on negative impacts of IT use. The panel seeks to (1) introduce a new area of exploration and (2) disseminate new points of view. The panelists will do so by drawing upon their research and practice related insights in five areas that characterize the dark side of IT use, namely - IT usage related stress, addiction, misuse, work overload, and interruptions. These are clearly important areas to examine, given that the ubiquitous and functionally pervasive nature of IT use in organizations is expected to expose users to ever greater levels of conditions that are potent for experiencing this dark side. The proposed panel is thus of relevance and interest to the IS research and practice communities.
Choice of departure station by railway users

This paper applies a multinomial logit model to the choice of a departure railway station by Dutch railway passengers. This is a relevant theme since about 50% of Dutch railway passengers do not travel via the nearest railway station. The passengers’ choices for departure stations are aggregated at the four digit postal code area level. We applied three functional forms for the underlying systematic utility of a station, namely a linear effect of attributes, cross effect of distance and frequency of service, and a translog formulation on distance and frequency of train services. With 3,498 post code areas and 360 railway stations our analysis found consistent effect sizes for distance, frequency of service, intercity status of the station and the presence of park-and-ride facility on the choice of departure station. The effect of distance on the choice of a departure station declines smoothly. The effect of frequency of service is relatively small compared to the effect of distance. A frequency of service increase by a hundred trains per day is equivalent to being 600 m closer to the station. The Intercity status of the station plays the biggest role in the choice of departure station. It has an equivalent effect of a change in 2 km distance or about a frequency of service of 300 trains per day. In addition, the presence of park-and-ride facility in the station poses a sizable effect in the departure station choice. In most cases its effect reaches about 35% of the intercity status effect.
The Association Between ADHD and Antisocial Personality Disorder (ASPD)

Objective: Children with ADHD have an increased risk of later developing personality disorders and criminal behavior. The object of the present review is to analyze the associations between ADHD and antisocial personality disorder (ASPD). Method: A review of literature was done using EMBASE, PsycINFO, and Medline databases. Results: Eighteen prospective studies (n = 5,501) showed that ADHD with and without comorbid conduct disorder (CD) is a strong predictor for the risk of later development of antisocial personality disorder (ASPD). Some of the 13 cross-sectional/retrospective studies (n = 2,451) suggested that ADHD and CD might be a separate subtype of ADHD, that especially impulsivity in ADHD is a predictor for later development of ASPD, or that callous-unemotional traits in the ADHD children are called for a risk factor for later ASPD. Conclusion: There is an increased risk for children with ADHD with or without comorbid CD to develop later onset of antisocial personality disorder.
VOLUNTARY AUDIT COMMITTEE CHARACTERISTICS IN FINANCIALLY DISTRESSED AND HEALTHY FIRMS: A STUDY OF THE EFFICACY OF THE ASX CORPORATE GOVERNANCE COUNCIL RECOMMENDATIONS

The aim of this paper is to address the impact of certain audit committee characteristics identified by the ASX Corporate Governance Council on improving the effectiveness of corporate audit committees on the likelihood of financial distress. Using a sample of 155 listed Australian firms, this paper finds support for the argument that the adoption of some, but not all, recommendations concerning the formation of an audit committee is beneficial for firms, which in this paper is reflected in a reduced likelihood of financial distress. In particular, the presence of a financial expert and solely nonexecutive directors on audit committee are associated with lower financial distress likelihood. By contrast, chairperson duality is significantly positively related to the probability of financial distress.
Polarization of the RF field in a human head at high field: A study with a quadrature surface coil at 7.0 T

The RF field intensity distribution in the human brain becomes inhomogeneous due to wave behavior at high field. This is further complicated by the spatial distribution of RF field polarization that must be considered to predict image intensity distribution. An additional layer of complexity is involved when a quadrature coil is used for transmission and reception. To study such complicated RF field behavior, a computer modeling method was employed to investigate the RF field of a quadrature surface coil at 300 MHz. Theoretical and experimental results for a phantom and the human head at 7.0 T are presented. The results are theoretically important and practically useful for high‐field quadrature coil design and application. Magn Reson Med 48:362–369, 2002. © 2002 Wiley‐Liss, Inc.
Underlying earnings reporting quality, equity overvaluation, and disclosure of intellectual capital: Australian evidence

University of Wollongong Copyright Warning You may print or download ONE copy of this document for the purpose of your own research or study. The University does not authorise you to copy, communicate or otherwise make available electronically to any other person any copyright material contained on this site. You are reminded of the following: This work is copyright. Apart from any use permitted under the Copyright Act 1968, no part of this work may be reproduced by any process, nor may any other exclusive right be exercised, without the permission of the author. Copyright owners are entitled to take legal action against persons who infringe their copyright. A reproduction of material that is protected by copyright may be a copyright infringement. A court may impose penalties and award damages in relation to offences and infringements relating to copyright material. Higher penalties may apply, and higher damages may be awarded, for offences and infringements involving the conversion of material into digital or electronic form. Unless otherwise indicated, the views expressed in this thesis are those of the author and do not necessarily represent the views of the University of Wollongong.
Hand preferences in the rhesus monkey. Implications for the study of cerebral dominance.

• Cerebral dominance is reflected in man by a seemingly inborn preference for the right hand in 80% to 90% of mature individuals. However, not all of the factors that govern human cerebral dominance are clearly understood. We studied rhesus monkeys to determine if hand preference in that primate also reflected a form of cerebral dominance and hence could be used to elucidate cerebral hemispheric asymmetry as it appears in man. Shortterm experiments provided positive evidence that experiential and environmental factors were sufficient to explain the originally observed hand preference in individual and groups of monkeys. We then demonstrated that training readily induced new hand preferences, further suggesting that monkey hand preference is primarily shaped by experience. Our evidence failed to support previous conclusions of right or left preference as a characteristic of the species. Although handedness based on inborn morphological and functional hemispheric asymmetry as seen in man was not demonstrated, the preferences induced by training in our monkeys were systematically altered by contralateral association cortical removals, suggesting that asymmetries of cerebral function may be acquired in monkeys.
Research on Coal Mine Enterprise Safety Production in China:From Perspective of Troop and Quality of Labor Force

This paper utilize the negotiation model between labor and management and the substitution model between wage and safety to explain how the quality of the labor force troop influence the safety level in enterprise.After retropecting the history of the change of the safety level of coal mining enterprise and the quality of the coal mining labor force,the paper analyze the relationship between safety level and the quality of the labor force by using econometrics method and verify the viewpoint that high quality labor force will favor the enterprise to improve safety level and low quality labor force unfavor the enterprise to improve safety level.The conclusion is that high proporation of peasant worker,the brain drain of specialities and the decline of the eduction and train cause the quality of coal mining labor force becoming lower and lower,and hence the safety level of coal mining enterprise can not be better in China.
Covalent Grafting of Phenylphosphonate Groups onto the Interlamellar Aluminol Surface of Kaolinite.

Kaolinite (K) was reacted with phenylphosphonic acid (PPA) in a water:acetone (1:1 V/V) solution (molar ratio 1 K:3 PPA), at 95 +/- 5 degreesC for different periods of time. Two different compounds (white powders) were identified but only one was isolated as a single phase and characterized by X-ray diffraction (powder method), thermal analysis (TG-DSC), Fourier-transformed infrared spectroscopy, and chemical analysis. The first compound showed a layer expansion of 7.86 Å and the second, a layer expansion of 9.29 Å, obtained as a decomposition product. Both compounds are consistent with the grafting of the phenylphosphonate group to the layers of kaolinite. The compounds have a formula of Al2Si2O5(OH)(HO3PPh)3.0 . 2H2O, as determined by thermal (water and total organic matter loss) and chemical (C content) analysis, respectively. Copyright 1998 Academic Press.
Whose ? L 2-English speakers ’ possessive pronoun gender errors

This article reports the results of an experiment on production of his/her in English as a second language (L2) by proficient native speakers of Italian, Spanish, and Dutch. In Dutch and English, 3rd person singular possessive pronouns agree in gender with their antecedents, in Italian and Spanish possessives in general agree with the noun they accompany (possessum). However, while in Italian the 3rd person singular possessives overtly agree in gender with the possessums, in Spanish they lack overt morphological gender marking. Dutch speakers were found to make very few possessive gender errors in any condition, Spanish and Italian speakers, on the other hand, behaved like Dutch speakers when the possessum was inanimate, but made more errors when it was animate (e.g., his mother). Thus, even proficient L2 speakers are susceptible to the influence of automatic processes that should apply in their first language alone. The pattern of results has implications for pronoun production and models of bilingual language production.
Additional tests of multi-index asset pricing models: evidence from an emerging market

ABSTRACT This study provides comprehensive evidence on the performance of asset pricing models in an emerging market setting. Tests are conducted on portfolios formed based on Fama–MacBeth betas, Fama–French size and book-to-market (B/M) factors, Carhart’s short- and long-term past returns and Pastor and Stambaugh’s liquidity beta. This is one of the first studies to provide emerging market evidence on Pastor and Stambaugh’s liquidity beta measuring a firm’s sensitivity to changing levels of market-wide liquidity. Results of the study are supported by metrics such as confidence intervals around the R2 values and the Gibbons-Ross-Shanken test. Similar to previous findings, the market factor is positive and significant even when models are augmented by the size and B/M factors that are themselves consistently significant and positive. Contrary to evidence from developed markets, contrarian, not momentum, strategies are preferred among the investors, especially for larger firms. Larger firms also are perceived to be less vulnerable when market-wide liquidity decreases.
Hubungan di antara tanggapan gaya kepimpinan, budaya organisasi dan pelaksanaan TQM di agensi kerajaan Negeri Pahang

Due to the importance of quality in delivering services to the people through the services provided by government agencies, organizations need to carry out activities to ensure that the quality of the service provided meets the quality required by the customers. The function of good leadership practices and the culture of the organization can also help and support quality activities to be implemented successfully within the organization. Therefore, this study aimed to investigate factors that affect the implementation of Total Quality Management (TQM) in the government agencies in Pahang. Specifically the objective of this study is to determine whether significant relationship exists between perceived leadership styles and TQM implementation. The study also aimed to determine the mediating effect of organizational culture on the relationship between perceived leadership styles and TQM implementation. The quantitative survey method was used to collect the data. Staff of the Pahang State government agencies were chosen as the sample for this study. A disproportionate stratified random sampling procedure was used to select the respondents. A total of 1,500 survey questionnaires were distributed and only 325 were returned, giving a response rate of 21.67 percent but only 277 could be used for further analysis. The findings indicated that significant relationship exists between the three variables (perceived transformational leadership style, perceived transactional leadership style and organizational culture) and TQM implementation. The study also found that organizational culture partially mediates the relationship between perceived transformational leadership style and TQM implementation and fully mediates the relationship between perceived transactional leadership style and TQM implementation. The study concluded with a discussion of the theoretical and managerial implications, and suggestions for future research.
Centrality in the network of Regional Trade Agreements: Effects on the strategies of the Arctic claimant states

This analysis differentiates two Arctic actors, Denmark and Russia, according to their centrality in the global Regional Trade Agreements network and the strength of their ties to other states in this system, in order to determine whether their positions coincide and have been stable throughout the last 24 years. The analysis reveals a significant stable heterogeneity between the Arctic actors not only in all three parameters of centrality (degree centrality, closeness centrality and betweenness centrality), but also in strength of the institutionalized ties these actors are involved in, and identifies the major sources of adjustment of regional (Arctic) policy preferences based on these global positions.
Safety and Effectiveness of VYC-15L, a Hyaluronic Acid Filler for Lip and Perioral Enhancement: One-Year Results From a Randomized, Controlled Study

BACKGROUND VYC-15L (Juvéderm Volbella XC) is a nonanimal crosslinked hyaluronic acid (HA) gel with lidocaine. OBJECTIVE To evaluate the safety and effectiveness of VYC-15L for lip and perioral enhancement versus a nonanimal stabilized HA with lidocaine (Restylane-L; NASHA). METHODS This prospective multicenter study randomized 225 adults with minimal, mild, or moderate lip fullness on the validated 5-point Allergan Lip Fullness Scale (LFS) to treatment with VYC-15L or NASHA; optional touch-up was administered 30 days later. Subjects were followed for 1 year. The primary effectiveness end point was noninferiority of VYC-15L versus NASHA by mean change in LFS score from baseline to Month 3. RESULTS The primary end point was met. At Month 3, LFS responder rates were 80.3% for VYC-15L versus 70.8% for NASHA. LFS responder rates exceeded 60% through 1 year with VYC-15L. Perioral lines severity improved for 65.4% and 66.2% of VYC-15L subjects at Month 3 and Year 1, respectively. At Month 3, 96.1% and 88.2% of subjects reported improvement in FACE-Q Satisfaction With Lips and Satisfaction With Lip Lines, respectively. Severe injection site responses were reported less frequently with VYC-15L than NASHA. CONCLUSION VYC-15L was safe and effective for lip and perioral enhancement, with treatment effects lasting through 1 year.
The Stock Market Price of Commodity Risk

Commodity prices are a risk factor that directly in‡uences in‡ation for consumers as well as input and output prices for …rms. We sort stocks according to their beta with respect to a broad index of commodity futures and …nd that commodity risk is priced. Our cross-sectional regressions imply that a unit exposure to commodity risk is rewarded with a premium of around 5% pre-2004 and -8.5% post-2003. We argue that commodity risk is likely to proxy for in‡ation risk and attribute the reversal to the surge in commodity index investment by institutions in the early 2000s. In a simple model in which investors are exposed to exogenous in‡ation risk, a switch from hedging in the stock market to hedging directly in the commodity market easily leads to the observed reversal in the risk premium. Both time-series and cross-sectional tests imply that the commodity factor is a separate additional risk factor, not replacing the traditional Fama-French-Carhart factors. JEL Classi…cation Codes: G11, G12, G13