Miracle-dz/UniFAR-FTUs huggingface dataset:
Neuropsychological Abilities of Preschool-Aged Children Who Display Hyperactivity and/or Oppositional-Defiant Behavior Problems

This study focused on gaining a better understanding of the neuropsychological abilities of preschool-aged children who show elevated levels of hyperactivity and oppositional-defiance. It examined the performance of children aged 48 to 67 months on tests of attention/executive function, language, memory, and sensorimotor abilities, as measured by the NEPSY and Conners' K-CPT. Two hundred thirty-seven children were divided into four subgroups based on mothers' report of behavior using rating scales and a diagnostic interview: hyperactive only (HYP), oppositional-defiant only (OD), hyperactive and oppositional-defiant (HYP/OD), and nonproblem. Children in the HYP/OD group scored significantly worse than nonproblem children on four of nine subtests on the NEPSY, including one test of executive function, one test of language comprehension, and both tests of short-term verbal memory. However, only the test of executive function (Statue) showed significant predictive power, and, while specificity of this subtest was good, sensitivity was poor. On the K-CPT, a continuous performance test, children in both the HYP and HYP/OD groups performed worse than children in the OD and nonproblem groups. When the NEPSY Statue subtest and the K-CPT were used together, overall predictive power was . 74. Results suggest that neuropsychological deficits can be observed among preschool children with hyperactivity, particularly when comorbid oppositional-defiance is present; however, moderate predictive power suggests that these tests should be used in conjunction with other methods of assessment.
Leukoencephalopathy among native indian infants in northern Quebec and Manitoba

We report 14 cases of a severe familial leukoencephalopathy among native North American Indian infants in northern Quebec and Manitoba. Affected infants have hypotonia and mild motor delay, followed by seizures, hypotonia or spasticity, eye deviation, and abnormal posture during a Februaryrile illness around 6 months of age. Death follows a rigid, vegetative state that manifests days to months after disease onset and is Marchked in some cases by prominent autonomic disturbances, blindness, and cessation of head growth. Symmetrical hemispheric white matter lucencies and diffuse hypomyelination of the cerebral hemispheres and brainstem are the radiological and pathological hallMarchks. This disease differs from the known diseases of cerebral myelin. An autosomal recessive pattern of inheritance awaits statistical confirmation. The proposed cause is a delay in development or abnormal turNovemberer of central nervous system myelin.
Effect of the addition of wheat fiber and partial pork back fat on the chemical composition, texture and sensory property of low-fat bologna sausage containing inulin and oat fiber

The objective of this work was to study the effect of adding wheat fiber and partial pork back fat on the quality characteristics of bologna sausage. The compound central rotating design was used with treatments containing fixed levels of inulin (5%) and oat fiber (1%) and variable levels of wheat fiber (0-4%) and pork back fat (0-10%). The pH and protein were similar in all the treatments, the fat was lower than the control treatment and the moisture content was higher than the control treatment (CF) without fibers. The wheat fiber increased the hardness and reduced cohesiveness and scores were given for overall impression. We found that it was possible to prepare low-fat bologna sausage with the addition of 6.58% fiber (5% inulin, 1% oat fiber and 0.58% wheat fiber), whilst retaining good sensory acceptability, thus reducing the pork back fat levels by between 25 and 42.75%.
Does FDI Bring Good Jobs to Host Countries?

Are jobs created by foreign investors good jobs? The evidence reviewed in this article is consistent with the view that jobs created by FDI are good jobs, both from the worker's and the country's perspective. From the worker's perspective, this is because such jobs are likely to pay higher wages than jobs in domestic firms, at least in developing countries, and because foreign employers tend to offer more training than local firms do. From the countrys perspective, jobs in foreign affiliates are good jobs because FDI inflows tend to increase the aggregate productivity of the host country.
Prognostic model for predicting survival in men with hormone-refractory metastatic prostate cancer.

PURPOSE To develop and validate a model that can be used to predict the overall survival probability among metastatic hormone-refractory prostate cancer patients (HRPC). PATIENTS AND METHODS Data from six Cancer and Leukemia Group B protocols that enrolled 1,101 patients with metastatic hormone-refractory adenocarcinoma of the prostate during the study period from 1991 to 2001 were pooled. The proportional hazards model was used to develop a multivariable model on the basis of pretreatment factors and to construct a prognostic model. The area under the receiver operating characteristic curve (ROC) was calculated as a measure of predictive discrimination. Calibration of the model predictions was assessed by comparing the predicted probability with the actual survival probability. An independent data set was used to validate the fitted model. RESULTS The final model included the following factors: lactate dehydrogenase, prostate-specific antigen, alkaline phosphatase, Gleason sum, Eastern Cooperative Oncology Group performance status, hemoglobin, and the presence of visceral disease. The area under the ROC curve was 0.68. Patients were classified into one of four risk groups. We observed a good agreement between the observed and predicted survival probabilities for the four risk groups. The observed median survival durations were 7.5 (95% confidence interval [CI], 6.2 to 10.9), 13.4 (95% CI, 9.7 to 26.3), 18.9 (95% CI, 16.2 to 26.3), and 27.2 (95% CI, 21.9 to 42.8) months for the first, second, third, and fourth risk groups, respectively. The corresponding median predicted survival times were 8.8, 13.4, 17.4, and 22.80 for the four risk groups. CONCLUSION This model could be used to predict individual survival probabilities and to stratify metastatic HRPC patients in randomized phase III trials.
Application of a general theory of deviant behavior: self-derogation and adolescent drug use.

The applicability of a general theory of deviant behavior to explaining drug use among junior high school students (N=3,148) is tested using data from a three-wave panel. The five-stage path model consists of eleven constructs measured at two points in time and one construct (drug use) measured at three points in time. The results of the analyses are consistent with the representation of drug use as the outcome of: (1) student's recognition of the self-devaluing implications of membership group experiences, (2) exacerbation of the self-esteem motive; and of the effects of these two concurrent processes, including decreased identification with the normative structure, increased perception of the self-enhancing potential of deviant responses, increased perception of the prevalence of drug use, and increased association with friends who use drugs.
Modeling of communication infrastructure compatible to Nordic 32 power system

Smart Grid integrates communication and computation technologies into power systems. Research on interdisciplinary topics between power system and communication systems requires models for both systems. There are several power system models available representing standard power systems and real power systems. However, lacking of their corresponding communication infrastructure information leads the difficulty of communication system modeling. In this paper, a communication infrastructure model compatible to Nordic 32 power system model has been developed and presented. In this model, Wide Area Monitoring System (WAMS) is incorporated with Supervisor Control and Data Acquisition system. The parameters of this model are based on the data from a Nordic electric power utility. Validation of the model is performed through comparison of results from simulation and a previous empirical data study performed on the same utility network. In additional, this model is simulated by using different Quality of Service (QoS) mechanism. The obtained results show that congestion management mechanisms introduce slight additional delay to the highest priority traffic. But traffics with lower priority can be benefit from congestion management mechanisms. The proposed model can be widely used for other research on Nordic 32 power system.
Low-dose dobutamine adds incremental value to late gadolinium enhancement cardiac magnetic resonance in the prediction of adverse remodelling following acute myocardial infarction.

AIMS To examine the relative and combined value of late gadolinium enhancement (LGE) and low-dose dobutamine (LDD) cardiac magnetic resonance (CMR) to predict 'adverse remodelling' (AR) following acute myocardial infarction (AMI). METHODS AND RESULTS Forty-five patients with AMI were recruited. CMR was performed 2-4 days after presentation and at 6 months. Ventricular wall motion and volume were recorded at rest and following dobutamine infusion. Measures of first pass perfusion, persistent microvascular obstruction (PMO), and LGE were obtained following contrast administration. Quantitation was performed using the MEDIS 6.2 software. Regression analysis was employed to determine the univariables and multivariate models most predictive of AR at 6 months. The incremental and relative value of LDD over LGE was investigated. The most predictive univariable was 'volume of PMO' (r = 0.51, r2 = 0.26, P < 0.001). The optimal 'combined' multivariate model, utilizing data from all components, was highly predictive of AR (r = 0.82, r2 = 0.67, P < 0.001). The optimal model using parameters only from the LGE component also predicted remodelling (r = 0.65, r2 = 42.0, P = 0.001) but with less accuracy. In contrast, the optimal model using variables from the LDD component alone predicted remodelling with a similar accuracy to the optimal combined model (r = 0.82, r2 = 0.67, P < 0.001). CONCLUSION A comprehensive CMR examination accurately predicts AR following AMI. LDD is superior to LGE CMR in this respect. These data suggest that LDD not only adds incremental value to LGE in the prediction of remodelling post-AMI but also may be utilized alone with the same predictive power.
Effects of intravenous fluid restriction on postoperative complications: comparison of two perioperative fluid regimens.

application of the DCR strategy with DCS provides the best results in the treatment of patients with bleeding from trauma. Conclusions. Current data on the use of intensive care for serious injuries, including severe gunshot wounds, have been analyzed in order to optimize resuscitation measures in patients with injuries and reduce mortality from uncontrolled bleeding. It has been shown that the strategy of DCR is more than one method or treatment, but rather a multi-component tactic that combines intensive care and surgical care. Such tactics focus on tolerable hypotension, restrictive infusion therapy, early prehospital blood transfusion, hemostatic resuscitation and empirical use of THA, prevention / correction of acidosis and hypothermia. It is emphasized that timely and correct use of DCR in combination with RDCR (at the prehospital level) improves survival, reduces the length of stay of patients in the intensive care unit, the incidence of long-term complications and mortality in such patients.
ANTERIOR APPROACH TO CELIAC PLEXUS BLOCK USING CT GUIDANCE

Theodosiadis P, Grosomanidis V, Touroutoglou N Neurolytic celiac plexus block (NCPB) is a useful technique for pain control in patients with intra-abdominal tumors or pain secondary to chronic pancreatitis that does not respond to other therapeutic modalities (not interventional). The anterior approach for NCPB has been considered a relatively safe approach, with a low rate of complications and little risk of neurologic injury secondary to the spread of a neurolytic agent. This is the first national case report of successful NCPB using the anterior approach under CT guidance.
Attitudes and beliefs concerning prostate cancer genetic screening

This quantitative study determines the values, beliefs, and attitudes influencing the intention of men to undergo or defer genetic testing for prostate cancer risk using a model based on components of the Theory of Reasoned Action and Health Belief Model. Telephone interviews of a community sample of 400 men in a large, East Coast metropolitan area of diverse educational, ethnic, and age backgrounds were conducted to rank key values and beliefs about genetic testing for prostate cancer risk in anticipation of its future availability. Descriptive statistics, univariate analyses, and logistic regression were used in data analysis. The factors of values attached to consequences, motivation from self, beliefs in benefits, and a motivation to comply with others (borderline) were statistically significant for testing intention. Of all demographics, only increased education was associated with diminished interest in testing. Desire to be tested varied widely across groups of men. Based on these identified values, health professionals can better understand men's values and beliefs on the risks and benefits of testing. The relationship of men to others, family and society, require further investigation in this and other aspects of genetic testing.
Examining Gender Discourse Differences in Shared Reviews about Books in eWOM

Today, user generated content and online shared opinions are gaining relevance as a source of information not only for other consumers but also for retailers. However, the huge number of posted opinions makes difficult any manual analysis. This paper proposes a new approach for gender discourse analysis based on the semantic analysis of the content of shared reviews in electronic word of mouth communities (eWOM). The paper includes a methodology for gathering online reviews as well as a statistical methodology to extract the differences between male and female in a specific category of product such as Books. Findings reveal not only the discourse references but also the different preferences of male and women, which can be interesting both for retailers and online recommendation systems.
Moxibustion for Stroke Rehabilitation: Systematic Review

Background and Purpose— Positive effects of moxibustion for stroke rehabilitation may be seen in real clinical practice. Currently, no systematic reviews are available. The aim of this systematic review was to analyze the trial data on the effectiveness of moxibustion for stroke rehabilitation. Methods— Fourteen databases were searched without language restriction. Randomized clinical trials were included if moxibustion was tested as the sole treatment or as an adjunct to other treatments for stroke rehabilitation. Results— Nine randomized clinical trials met our inclusion criteria. Three randomized clinical trials reported favorable effects of moxibustion plus standard care on motor function versus standard care alone (N=142; standardized mean difference=0.72; 95% confidence interval, 0.37 to 1.08; P<0.0001). Three randomized clinical trials compared the effects of moxibustion on activities of daily living alone but failed to show favorable effects of moxibustion. Conclusion— This systematic review found limited effectiveness of moxibustion as an adjunct to standard care in stroke rehabilitation.
Low power microheater-based combustible gas sensor with graphene aerogel catalyst support

This paper reports a microheater-based combustible gas sensor with ultra-low power consumption (1.4 mW) using pulsed heating and novel sensing materials. High surface area graphene aerogel is used as a support for platinum and palladium nanoparticles. Pulsed heating (450 °C) at a 10% duty cycle yields an order of magnitude reduction in power consumption with no loss of sensitivity. Sensing response to hydrogen and propane gas shows promising selectivity and order of magnitude faster response and recovery times (1-2 s) compared to previous work. The results indicate a high level of flexibility in creating selective, low power combustible gas sensors using this microheater platform and catalytic material system.
Ca2+ Inhibition of Type III Adenylyl Cyclase in Vivo(*)

Type III adenylyl cyclase is stimulated by β-adrenergic agonists and glucagon in vitro and in vivo, but not by Ca2+ and calmodulin. However, the enzyme is stimulated by Ca2+ and calmodulin in vitro when it is concomitantly activated by the guanyl nucleotide stimulatory protein Gs (Choi, E. J., Xia, Z., and Storm, D. R. (1992a) Biochemistry 31, 6492-6498). Here, we examined regulation of type III adenylyl cyclase by Gs-coupled receptors and intracellular Ca2+in vivo. Surprisingly, intracellular Ca2+ inhibited hormone-stimulated type III adenylyl cyclase activity. Submicromolar concentrations of intracellular free Ca2+, which stimulated type I adenylyl cyclase, inhibited glucagon- or isoproterenol-stimulated type III adenylyl cyclase. Inhibition of type III adenylyl cyclase by intracellular Ca2+ was not mediated by Gi, cAMP-dependent protein kinase, or protein kinase C. However, an inhibitor of CaM kinases antagonized Ca2+ inhibition of the enzyme, and coexpression of constitutively activated CaM kinase II completely inhibited isoproterenol-stimulated type III adenylyl cyclase activity. We propose that Ca2+ inhibition of type III adenylyl cyclase may serve as a regulatory mechanism to attenuate hormone-stimulated cAMP levels in some tissues.
Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain

Self‐resolving inflammatory exudates and lipid mediator metabolomics recently uncovered a new family of potent anti‐inflammatory and proresolving mediators biosynthesized by macrophages (MΦs), denoted maresins. Here we determined that maresin 1 (MaR1) produced by human MΦs from endogenous docosahexaenoic acid (DHA) matched synthetic 7R,14S‐dihydroxydocosa‐4Z,8E,10E,12Z,16Z,19Z‐hexaenoic acid. The MaR1 alcohol groups and Z/E geometry of conjugated double bonds were matched using isomers prepared by total organic synthesis. MaR1's potent defining actions were confirmed with synthetic MaR1, i.e., limiting polymorphonuclear neutrophil (PMN) infiltration in murine peritonitis (ng/mouse range) as well as enhancing human macrophage uptake of apoptotic PMNs. At 1 nM, MaR1 was slightly more potent than resolvin D1 in stimulating human MΦ efferocytosis, an action not shared by leukotriene B4. MaR1 also accelerated surgical regeneration in planaria, increasing the rate of head reappearance. On injury of planaria, MaR1 was biosynthesized from deuterium‐labeled (d5)‐DHA that was blocked with lipoxygenase (LOX) inhibitor. MaR1 dose‐dependently inhibited TRPV1 currents in neurons, blocked capsaicin (100 nM)‐ induced inward currents (IC50 0.49±0.02 nM), and reduced both inflammation‐ and chemotherapy‐induced neuropathic pain in mice. These results demonstrate the potent actions of MaR1 in regulating inflammation resolution, tissue regeneration, and pain resolution. These findings suggest that chemical signals are shared in resolution cellular trafficking, a key process in tissue regeneration. Moreover, immunoresolvents of the innate immune response, such as MaR1, offer new opportunities for assessing MΦs and their local DHA metabolome in the return to tissue homeostasis. —Serhan, C. N. , Dalli, J., Karamnov, S. , Choi, A. , Park, C. ‐K. , Xu, Z. ‐Z. , Ji, R. ‐R. , Zhu, M. , Petasis, N. A. Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain. FASEB J. 26, 1755‐1765 (2012). www.fasebj. org
On a Structured Model for Load-Dependent Reaction Kinetics of Transient Elastic Linkages Mediating Nonlinear Friction

We consider a microscopic model for friction mediated by transient elastic linkages introduced in [D. Oelz and C. Schmeiser, Arch. Ration. Mech. Anal. , 198 (2010), pp. 963--980; D. Oelz, C. Schmeiser, and V. Small, Cell Adh. Migr. , 2 (2008), pp. 117--126]. In this study we extend results and the general approach employed in [V. Milisic and D. Oelz, J. Math. Pures Appl. (9), 96 (2011), pp. 484--501]. We introduce a new unknown and reformulate the model. Based on this framework, we derive new a priori estimates. In a first step this approach allows us to reproduce results of our earlier paper concerning the convergence of the system to a macroscopic friction law in the semicoupled case, but under weaker assumptions. Furthermore, we consider the fully coupled case and prove existence and uniqueness of the solution.
Twin studies in inherited eye disease

Eye diseases represent a significant source of health impairment in humans. Twin studies offer an excellent model to dissect the genetic basis of human diseases. In this review, we discuss the potential advantages of using twin‐based studies in investigating the genetics of eye diseases – from heritability estimation to identifying underlying genetic and epigenetic changes. We also discuss some of the notable findings of twin studies exploring the genetics of eye diseases. Finally, we suggest other novel approaches that can be utilized to tap the potential of twin studies to provide a more complete understanding of genetic factors underlying ocular diseases.
Reductions in Medicare Payments and Patient Outcomes: An Analysis of 5 Leading Medicare Conditions

Background:The Affordable Care Act enacted significant Medicare payment reductions to providers, yet the effects of such major reductions on patients remain unclear. We used the Balanced Budget Act (BBA) of 1997 as a natural experiment to study the long-term consequence of major payment reductions on patient outcomes. Objectives:To analyze whether mortality trends diverge over the years between hospitals facing different levels of payment cuts because of the BBA for 5 leading conditions: acute myocardial infarction, congestive heart failure, stroke, pneumonia, and hip fracture. Research Design:Using 100% Medicare claims between 1995 and 2005, hospital database, and published reports on BBA policy components, we compared changes in outcomes between hospitals facing small and large BBA payment reductions across 3 periods (pre-BBA, initial-BBA, and post-BBA) using instrumental variable hospital fixed-effects regression models. Setting:All general, acute, nonrural, short-stay hospitals in the United States 1995—2005. Main Outcome Measures:Hospital risk-adjusted mortality rates (7, 30, 90 d, and 1 y). Results:Mortality trends between hospitals in small and large payment-cut categories were similar between pre-BBA and initial-BBA periods, but diverged in the post-BBA period. Relative to the small-cut hospitals, hospitals in the large-cut category experienced smaller decline in 1-year mortality rates in the post-BBA period compared with their pre-BBA trends by 0.8–1.4 percentage points, depending on the condition (P<0.05 for all conditions, except for hip fracture). Conclusion:We found consistent evidence across multiple conditions that reductions in Medicare payments are associated with slower improvement in mortality outcomes.