Miracle-dz/UniFAR-FTUs huggingface dataset:
Gastric emptying and fluid availability after ingestion of glucose and soy protein hydrolysate solutions in man

The double sampling gastric aspiration method was used to measure the effect of energy content on the rate of gastric emptying of glucose and soy protein hydrolysate solutions. The net rate of absorption of water from these solutions was assessed using deuterium oxide as a tracer for water. Six healthy male subjects were each studied on four separate occasions using a test drink volume of 600 ml. The half emptying times (t1/2, median (range)) of the iso‐energetic soy protein hydrolysate (6P, 60 g l−1, 36 (14–39) min) and glucose (7G, 70 g l−1, 25 (19–29) min) solutions were similar. These two solutions (6P, 7G) delivered energy to the small intestine at similar rates, and resulted in similar rates of accumulation of the deuterium tracer in the circulation. The dilute glucose solution (LG, 23 g l−1) was emptied faster (t1/2 13 (11–19) min) and resulted in a faster rate of tracer accumulation in the circulation than any of the other solutions, including the iso‐osmotic soy protein solution (LG 311 ± 5 mosmol kg−1, 6P 321 ± 24 mosmol kg−1). The concentrated soy protein hydrolysate solution (12P, 120 g l−1) emptied more slowly (t1/2 80 (44–120) min) than the more dilute solutions. The rate of energy delivery to the small intestine from 12P was similar to that from 6P for the first 50 min after ingestion, and similar to that from 7G at all sample points. These results indicate that the iso‐energetic solutions of glucose and soy protein hydrolysate used in this study are emptied from the stomach at similar rates and result in similar rates of fluid availability after ingestion.
Partial Hydatidiform Mole: Histologic Parameters in Correlation With DNA Genotyping

Histologic diagnosis of partial hydatidiform mole (PHM) continues to be problematic, and DNA genotyping has recently become cost-effective for precise separation of PHM from its mimics. We performed a comprehensive reevaluation of histologic parameters of PHM in correlation with DNA genotyping. A total of 143 early abortion specimens were subjected to genotyping as part of the routine workup, resulting in 60 cases of PHM, 52 cases of various chromosomal trisomies, and 31 cases of nonmolar diploid gestations. All available hematoxylin and eosin slides were reviewed retrospectively by 2 gynecologic pathologists blinded to the genotyping results. Significant histologic overlaps were present among genetically confirmed PHM, hydropic abortions, and chromosomal trisomy syndromes. The following morphologic parameters emerged with diagnostic significance for PHM: villus size, presence of 2 villous populations, round or oval pseudoinclusions, at least moderate villous hydrops, cistern formation, and trophoblastic hyperplasia. The most sensitive morphologic features for PHM included villous hydrops (86% sensitivity) or the presence of at least 1 of the following 3 parameters: 2 villous populations, round or oval pseudoinclusions, and cisterns (84% sensitivity). The presence of cisterns and villous size ≥2.5 mm had the highest positive predictive value (90%) for PHM. In conclusion, no single or combined morphologic features are sufficient for definitive diagnosis of PHM. The presence of any one of the following histologic findings should prompt DNA genotyping workup to rule out PHM: round or oval pseudoincludions, cistern formation, 2 populations of villi, and a villous size of ≥2.5 mm.
The Effect of Stress on Blood Pressure and Heart Rate of High School Girls

Purpose: The purpose of this research was to study the changes of Systolic blood pressure, diastolic blood pressure, and heart rate in the period of the examination, particularly the physics exam for the girls in high school. Materials and Methods: For the purpose of this study, 58 students were randomly selected (age: 16.58 ± 0.56 years old, height: 157.89 ± 6.64 cm, weight: 53.72 ± 7.3 kg and body mass index (BMI): 21.08 ± 2.96). Their systolic and diastolic blood pressure and heart rate relaxation state were measured and recorded as the first phase. By the 28th day, in the period of the examination, and precisely 15 minutes before the physics exam, the same variables were measured once more, and recorded as the second phase. Results: The results of the research, using the one sample t test, proved that there is a significant difference between the average systolic and diastolic bloodpressure in the first phase and the second phase (P = 0.002). Moreover, the comparison of the averages of the heart rates of the subjects proved a significant difference between these two phases (0.0001), (α=0.05). Conclusion: The final result of this research proved that the high school physics examination might cause significant changes in the blood pressure and the heart rate of the high-school students.
FACTORS AFFECTING ROAD TRAFFIC NOISE ANNOYANCE AMONG WHITE-COLLAR EMPLOYEES WORKING IN TEHRAN

The effect of personal and attitudinal factors, noise level, hearing status and psychological traits on traffic-related noise annoyance among white-collar employees working in Tehran has been carefully analyzed. This survey has been conducted by interviewing 495 citizens working in non-manufacturing industries in Tehran, using questionnaires, Weinstein noise sensitivity scale, Beck’s depression, Buss and perry’s aggression, Zung’s anxiety, job satisfaction and Eysenc’s personality inventory. These citizens were office workers or store employees. Noise annoyance was determined both by numerical-based questionnaire criterion and by verbal index. Personal information, attitudinal factors and hearing conditions were determined using a general questionnaire. The amount of workplace noise the participants were exposed to was directly measured at their workplaces. It was revealed that among personal factors, age (p=0.030), marital status (p=0.004), residential period (p=0.001) and wealth (p=0.04) were related to noise annoyance. Attitudinal factors including sensitivity to noise (p=0.001), individual’s opinion on the need to control the noise (p=0.000) and individuals’ assessment of the amount of the workplace ambient noise (p= 0.000) were found to have relationship with noise annoyance. No meaningful relationship was seen between the equivalent noise level (p=0.879) and statistical noise level of L90 (p=0.909). The present study revealed that among all effective factors involved in noise annoyance, attitudinal factors had the most significant role in this regard.
Impact of technology scaling on the combinational logic soft error rate

Experimental results from alpha particle irradiation of 40-nm, 28-nm and 20-nm bulk technology circuits operating in the GHz range suggest that the combinational logic soft error rate (SER) per logic gate decreases with scaling. This rate of decrease for the logic SER with scaling, however, is not as high as that of the latch SER. As a result, the proportion of combinational logic soft errors at the chip level is shown to increase. Results suggest that alpha-particle logic SER of average sized circuits is about 20% of the latch SER at 20-nm node while it is only 10% at 40-nm at 500 MHz. Moreover, the frequency at which combinational logic SER exceeds latch SER decreases with scaling. Factors that influence logic soft error scaling trends, such as sensitive area, transient pulse-widths and latch characteristics, are estimated through simulations and soft-error rate predictions for future technology nodes are made.
Mortgage Arrears, Regulation and Institutions: Cross-Country Evidence

Using a newly constructed database for 26 countries over 2000-2014, we analyze cross-country and within-country differences in mortgage arrears. We find that restrictive macro-prudential policies, in particular lower regulatory loan-to-value ratios, are significantly associated with a lower share of mortgage arrears in total residential debt. Likewise, better institutions are related with lower delinquency rates, both directly and by enhancing the impact of macro-prudential policies and the right to recourse. We also find that the effect of macro-prudential policies is conditioned by several mortgage market characteristics, such as the maturity of loans, interest rate fixity, and tax deductibility of interest payments.
Drosophila and Caenorhabditis elegans as Discovery Platforms for Genes Involved in Human Alcohol Use Disorder.

BACKGROUND Despite the profound clinical significance and strong heritability of alcohol use disorder (AUD), we do not yet have a comprehensive understanding of the naturally occurring genetic variance within the human genome that drives its development. This lack of understanding is likely to be due in part to the large phenotypic and genetic heterogeneities that underlie human AUD. As a complement to genetic studies in humans, many laboratories are using the invertebrate model organisms (iMOs) Drosophila melanogaster (fruit fly) and Caenorhabditis elegans (nematode worm) to identify genetic mechanisms that influence the effects of alcohol (ethanol) on behavior. While these extremely powerful models have identified many genes that influence the behavioral responses to alcohol, in most cases it has remained unclear whether results from behavioral-genetic studies in iMOs are directly applicable to understanding the genetic basis of human AUD. METHODS In this review, we critically evaluate the utility of the fly and worm models for identifying genes that influence AUD in humans. RESULTS Based on results published through early 2015, studies in flies and worms have identified 91 and 50 genes, respectively, that influence 1 or more aspects of behavioral responses to alcohol. Collectively, these fly and worm genes correspond to 293 orthologous genes in humans. Intriguingly, 51 of these 293 human genes have been implicated in AUD by at least 1 study in human populations. CONCLUSIONS Our analyses strongly suggest that the Drosophila and C. elegans models have considerable utility for identifying orthologs of genes that influence human AUD.
Internet banking adoption in Egypt: Extending technology acceptance model

: The increased expansion of E-commerce and internet along with the development of technology has changed business operations and functioning. Internet banking is considered an opportunity for banks to have differentiated services provided for their customers. The purpose of this paper is to investigate the factors that affect customers’ adoption of internet banking in Egypt in light of technology acceptance model (TAM). The study adopted a quantitative approach through distributing questionnaires in public and private banks’ customers operating in Egypt. The results indicated that website characteristics, computer efficacy, and perceived risk had a direct impact on customers’ adoption of internet banking . These variables were considered an extension to TAM when studying internet banking adoption. It is suggested that financial banks give continuous attention to their websites and provide their customers with easy and useful access to internet banking services. Banks should be concerned with inhibitors of internet banking such as perceived risk in order to keep existing customers and attract new ones. This paper is the first to investigate the factors that affect customers’ adoption of internet banking in Egypt after banks introduced many of their services over their websites.
The Input Power Dynamic Range of a Semiconductor Optical Amplifier and Its Relevance for Access Network Applications

The input power dynamic range (IPDR) of a semiconductor optical amplifier (SOA) gives the input power range within which an SOA can be operated error free. It is among the most important parameters describing the usability range of an SOA in an access network. In this paper, we give design guidelines to maximize the IPDR at a given gain. Our IPDR description indicates that a large IPDR can be obtained if SOAs are designed properly. A particular large IPDR is predicted to be found for well-designed quantum-dot (QD)-SOAs. We apply both theory and experiment to a 1.3- μm QD-SOA and investigate the IPDR as a function of bitrate, wavelength, and bias current. Large IPDRs of 41 and 36 dB are found for single-channel experiments with a signal quality of Q2 = 12.6 dB at 2.5 and 40 Gbit/s, respectively.
Cholesterol Primes Vascular Smooth Muscle to Induce Ca2+ Sensitization Mediated by a Sphingosylphosphorylcholine–Rho-Kinase Pathway: Possible Role for Membrane Raft

Hypercholesterolemia is a major risk factor involved in abnormal cardiovascular events. Rho-kinase–mediated Ca2+ sensitization of vascular smooth muscle (VSM) plays a critical role in vasospasm and hypertension. We recently identified sphingosylphosphorylcholine (SPC) and Src family tyrosine kinase (Src-TK) as upstream mediators for the Rho-kinase–mediated Ca2+ sensitization. Here we report the strong linkage between cholesterol and the Ca2+ sensitization of VSM mediated by a novel SPC/Src-TK/Rho-kinase pathway in both humans and rabbits. The extent of the sensitization correlated well with the total cholesterol or low-density lipoprotein cholesterol levels in serum. However, an inverse correlation with the serum level of high-density lipoprotein cholesterol was observed, and a correlation with other cardiovascular risk factors was nil. When cholesterol-lowering therapy was given to patients and rabbits with hypercholesterolemia, the SPC-induced contractions diminished. Depletion of VSM cholesterol by &bgr;-cyclodextrin resulted in a loss of membrane caveolin-1, a marker of cholesterol-enriched lipid raft, and inhibited the SPC-induced Ca2+ sensitization and translocation of Rho-kinase from cytosol to the cell membrane. Vasocontractions induced by membrane depolarization and by an adrenergic agonist were cholesterol-independent. Our data support the previously unreported concept that cholesterol potentiates the Ca2+ sensitization of VSM mediated by a SPC/Src-TK/Rho-kinase pathway, and are also compatible with a role for cholesterol-enriched membrane microdomain, a lipid raft. This process may play an important role in the development of abnormal vascular contractions in patients with hypercholesterolemia.
Can We Use the Fellow Eye Biometric Data to Predict IOL Power?

ABSTRACT Purpose: To study the correlation between right (RE) and left eye (LE) keratometry readings (K) and axial lengths (AL) in a population-based sample of normal subjects. Methods: In a cross-sectional retrospective study conducted at S. Giuseppe Moscati Hospital, Avellino, Italy, 4516 eyes of 2258 patients with a mean age of 67 ± 16.36 years (range 18–96 years) were included. Partial coherence interferometry data obtained in right (RE) and left (LE) eyes were analyzed and correlated. Results: The average K was 44.01 ± 1.50 diopters (D) (range 39.09–49.89 D) in the RE and 44.04 ± 1.53 D (range 39.63–51.89 D) in the LE (p = 0.0075). 4.5% of the patients (101) presented with differences in the corneal power ≥ 1 D, corresponding to a difference of roughly 1 D in the IOL power. The average AL was 23.89 ± 1.77 mm (range 19.09–35.15 mm) in the RE and 23.84 ± 1.68 mm (range 19.23–35.04 mm) in the LE (p = 0.0018). 19.2% of the patients (433) presented with differences in the AL ≥ 0.4 mm, corresponding to a difference of roughly 1 D in the IOL power. Conclusions: In calculating the IOL power, we must be aware of these results when we measure the fellow eye to validate the measurements in the first eye. In the case of postcataract refractive error, the outcome could be used for the second eye only when symmetric biometric findings are present.
Nurse practice environments and outcomes: implications for oncology nursing.

PURPOSE/OBJECTIVES To examine practice environments and outcomes of nurses working in oncology units or Magnet hospitals and to understand the association between the two. DESIGN Secondary analysis of survey data collected in 1998. SETTING Medical and surgical units of 22 hospitals, of which 7 were recognized by the American Nurses Credentialing Center Magnet program. SAMPLE 1,956 RNs, of whom 305 worked in oncology units. METHODS Chi-square tests compared nurse-reported outcomes by work setting, analysis of variance tested practice environment differences by setting, and logistic regression estimated the effects of practice environment, specialty, and Magnet status on outcomes. MAIN RESEARCH VARIABLES Practice environments, emotional exhaustion, job satisfaction, and quality of care. FINDINGS Oncology nurses had superior outcomes compared with nononcology nurses. Emotional exhaustion was significantly lower among oncology nurses working in Magnet hospitals. Scores on the Collegial Nurse-Physician Relations subscale were highest among oncology nurses. Outcomes were associated with Practice Environment Scale of the Nursing Work Index scores and Magnet status. Oncology nurses with favorable collegial nurse-physician relations were twice as likely to report high-quality care. CONCLUSIONS Oncology nurses benefit from working in American Nurses Credentialing Center Magnet hospitals. Adequate staffing and resources are necessary to achieve optimal outcomes. Collegial nurse-physician relations appear to be vital to optimal oncology practice settings. IMPLICATIONS FOR NURSING In addition to pursuing American Nurses Credentialing Center Magnet recognition, nurse managers should assess practice environments and target related interventions to improve job satisfaction and retention. High-priority areas for interventions include ensuring adequate staff and resources, promoting nurse-physician collaboration, and strengthening unit-based leadership.
Liquidity Risk and Macroeconomic Analysis of Islamic Banking in Indonesia

: The purpose of this study is to identify macroeconomic factors affecting the risk of liquidity of Islamic banks in Indonesia. The method of this research is explanatory research. This study uses secondary data derived from Islamic bank financial statements and statistical center in Indonesia. The result of the research shows that there is no significant influence on GDP, Inflation and Unemployment on liquidity risk. This means that macroeconomic conditions in Indonesia do not affect liquidity risk in Islamic banks in Indonesia. The results of this study is different from the results of previous research, this is due to differences in sample data. Previous research was conducted on conventional banks, while in this study conducted on Islamic banks. This proves that liquidity risk in Islamic banks in Indonesia is more resistant to macroeconomic factors than conventional banks.
Blood Pressure Behaviour in Chronic Daily Headache

The objective was to examine the association between high blood pressure (BP) and chronic daily headache using 24-h ambulatory blood pressure monitorization (24-h ABPM). This was a cross sectional study in an out-patient clinic. Women were selected among patients referred for first evaluation, 62 with chronic daily headache and 57 without chronic daily headache. The main outcome measures were mean office systolic and diastolic blood pressure (BP), mean systolic and diastolic daytime and night-time BP and BP load, and mean systolic and diastolic nocturnal fall. Office systolic BP was 138.2 mmHg for women with chronic daily headache and 141.7 mmHg for women without headache (P = 0.36). Office diastolic BP was 88.9 mmHg for women with headache and 92.7 mmHg for women without headache (P = 0.17). Mean daytime and mean night-time systolic BP was, respectively, 122.2 mmHg and 108.8 mmHg for women with headache and 122.9 mmHg and 109.5 for women without headache (P = 0.82 and P = 0.80, respectively). Mean daytime and mean night-time diastolic BP was, respectively, 78.6 mmHg and 65.4 mmHg for women with headache and 79.9 mmHg and 67.1 mmHg for the women without headache (P = 0.80 and P = 0.45, respectively). There was no difference between the two groups regarding systolic and diastolic BP load and nocturnal systolic and diastolic fall. No significant difference in BP values was observed in women with chronic daily headache compared with women without headache using 24-h ABPM.
Recovery of Renal Function after Renovascular Surgery

A 48-year-old woman with generalised atheromatous disease had a right nephrectomy for a renal artery occlusion in 1977. Fourteen months later she presented with severe hypertension and anuria, caused by occlusion of the left renal artery. Emergency reconstructive surgery was successful in bringing about recovery of renal function and lowering of her blood pressure. Because renal function had deteriorated slightly after the first operation and improved after the second, a comparison was made of the effects of unilateral nephrectomy and reconstructive surgery on renal function in a further 26 patients with renal artery stenosis. In 15 patients having nephrectomy, renal function deteriorated in most, while in 11 having reconstruction it improved in nine and remained constant in two.
[Association of the Thr241Met polymorphism of DNA repair gene XRCC3 with genetic susceptibility to AFB1-related hepatocellular carcinoma in Guangxi population].

OBJECTIVE To explore the association of the Thr241Met polymorphism of X-ray cross-complementing group 3 (XRCC3) gene with genetic susceptibility to aflatoxin B1(AFB-1)-related hepatocellular carcinoma (HCC)in Guangxi population. METHODS We conducted a hospital-based case-control study, including 257 HCC cases and 711 controls without cancers or liver diseases. The XRCC3 Thr241Met polymorphism was analyzed by PCR. RESULTS The XRCC3 genotypes XRCC3-Thr/Met or XRCC3-Met/Met were related with an elevated risk of HCC. The risk of HCC was associated with the number of mutant Met copies (adjusted OR were 2.20 and 8.56 for XRCC3-Thr/Met and Met/Met, respectively); moreover, there seemed to be combined effects for HCC risk between the variant genotypes and AFB1-DNA adduct levels from peripheral blood leukocytes (adjusted OR was 2.34 to 20.44, P < 0.01). CONCLUSION These results suggested that XRCC3 polymorphism may be associated with the risk of AFB1- related HCC among the Guangxi population, and interacts with AFB1 exposure in the development of HCC induced by AFB1.
The early life origins of vascular ageing and cardiovascular risk: the EVA syndrome

Early vascular ageing is common in patients with hypertension and increased burden of cardiovascular risk factors, often influenced by chronic inflammation. One aspect of this vascular ageing is arterial stiffening, as measured by increased pulse wave velocity or augmentation index and central pressure. Several studies have indicated that this process starts early in life and that arterial function and ageing properties could be programmed during foetal life or influenced by adverse growth patterns in early postnatal life. This could explain the repeated findings in observational epidemiology that an inverse association exists between birth weight, adjusted for gestational age, and systolic blood pressure elevation in childhood, adolescence and adulthood, as well as for increased cardiovascular risk. One new marker of increased pulse pressure and arterial ageing is telomere length, as regulated by telomerase enzymatic activity. Future studies will hopefully shed light on the possibilities to halt or even reverse vascular ageing, and thereby also influence telomere biology and its different expressions.
Factor analysis of objective and subjective characteristics of a night's sleep

Synopsis Factor analysis was performed on objectively measured and subjectively reported characteristics of 46 nights' sleep in four healthy male subjects. The fragmentation of sleep by awakenings during the night, the delay before falling asleep, the total duration of sleep, and the amount of delta-wave sleep formed the bases of four separate factors.