Miracle-dz/UniFAR-FTUs huggingface dataset:
First Reported Case of Dog Associated Cattle Rabies in Koinadugu District, Northern Sierra Leone

Cattle rabies is uncommon and often associated with vampire bats, dog and foxes however there is paucity of information on this condition in other West African countries other than Nigeria. This communication presents a case of dog associated cattle rabies in Koinadugu district, Sierra Leone. Case history, antirabies vaccination and dog management assessment in adjoining communities, human exposure, clinical presentations and mortality in affected cattle were evaluated using standard techniques. Laboratory screening of brain samples collected was by Real time polymerase chain reaction technique. Stray dog bitten affected cattle showed anorexia, barking, hyper excitation, hydrophobia, foaming and paralysis with resultant category 1 and 11 human exposure, 7.6% mortality and 100% case fatality rate. Laboratory examination of cattle brain specimens tested positive for Rabies virus. This report described the first documented case of dog associated cattle rabies in Sierra Leone. This communication emphasizes on continued advocacy for antirabies vaccination and education of herdsmen and community on proper dog management
Predictors of Kidney Damage in Newly-Diagnosed Hypertensive Nigerians

Systemic hypertension is an important cause of chronic kidney disease. Identifying predictors of hypertensive kidney damage provides clinicians with opportunity for appropriate therapeutic interventions. This will forestall kidney damage and prevent development of chronic kidney disease. The study aims at determining predictors of kidney damage using microscopic haematuria as surrogate marker in newly diagnosed hypertensive patients. A cross sectional study of 138 newly diagnosed hypertensive Nigerian, matched with age and sex controls was conducted. The surrogate marker of kidney damage was microscopic haematuria defined as 3/hpf, determined by examination of urine sediment under a bright field microscope after application of Sternheimer’s stain. Potential predictors of kidney damage evaluated were: age, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood pressure (MAP), pulse pressure (PP), and body mass index (BMI). Mean age of the patients was 43.2±9.6years and 76 (55%) were males. SBP correlates positively with kidney damage (r=0.209, p=0.048). Stepwise regression models identified SBP as the best sole predictor of kidney damage (r=0.557, r2=0.310, adjusted r2=0.272, df=1, P=0.011), followed by age (r=0.72, r2=0.505, adjusted r2=0.447, df=2, P=0.019). Other variables were rejected by the model (probability level of entrance was 0.05 and removal, 0 0.1). The study suggests that systolic blood pressure may predict kidney damage in newly diagnosed hypertensive patients, and it seems to be amplified with increasing age. A longitudinal studywith larger population is recommended to confirm this relationship.
Respiratory Syncytial Virus Prophylaxis in Infants With Congenital Diaphragmatic Hernia in the Canadian Respiratory Syncytial Virus Evaluation Study of Palivizumab, 2005–2017

Abstract Background Infants with congenital diaphragmatic hernia (CDH) are at an increased risk of respiratory morbidity from recurrent respiratory tract infections including those from respiratory syncytial virus (RSV). Prospective studies on RSV prophylaxis in CDH infants are limited. We determined the risk of respiratory illness– and RSV-related hospitalizations (RIH and RSVH, respectively) among infants prophylaxed for CDH, standard indications (SIs) and those without increased risk (NR). Methods The prospective Canadian Respiratory Syncytial Virus Evaluation Study of Palivizumab (CARESS) registry was searched for infants who received palivizumab during 12 RSV seasons (2005–2017) in Canada. Cox proportional hazards analyses were conducted to compare RIH and RSVH risks across the groups adjusted for potential confounders. Results In total, 21 107 infants (201 CDH, 389 NR, and 20 517 SI) were included. RIH incidences were 10.0% (CDH), 2.1% (NR), and 6.2% (SI). CDH patients had a significantly higher RIH hazard compared with NR (hazard ratio [HR], 3.6 [95% confidence interval {CI}, 1.5–8.8]; P = .005) but not SI (HR, 1.2 [95% CI, .8–2.0]; P = .379). RSVH incidences were 0.6%, 0.3%, and 1.5% for CDH, NR, and SI, respectively. RSVH risk was similar across groups (SI: HR, 0.0, P = .922; NR: HR, 0.0, P = .934). Conclusions CDH infants had a 3-fold increased risk of RIH compared to NR but not SI infants. RSVH risk was similar with low RSVH incidences across all groups, implying that CDH infants may benefit from palivizumab during the RSV season, similar to other high-risk groups. Clinical Trials Registration NCT00420966.
Discriminative multi-layer feed-forward networks

The authors propose a new family of multi-layer, feed-forward network (FFN) architectures. This framework allows examination of several feed-forward networks, including the well-known multi-layer perceptron (MLP) network, the likelihood network (LNET) and the distance network (DNET), in a unified manner. They then introduce a novel formulation which embeds network parameters into a functional form of the classifier design objective so that the network's parameters can be adjusted by gradient search algorithms, such as the generalized probabilistic descent (GPD) method. They evaluate several discriminative three-layer networks by performing a pattern classification task. They demonstrate that the performance of a network can be significantly improved when discriminative formulations are incorporated into the design of the pattern classification networks. <<ETX>>
Clinical performance of immediately loaded single-tooth implants up to 7-year: a retrospective study review article

Objectives: This study retrospectively evaluated the survival rates of immediately loaded implants supporting single crowns, and investigated causes of failures. Methods: A total of 90 dental implants (Branemark System® and Replace® Select) supporting single crowns, were placed in 88 patients (35 male, 53 female, mean age: 51.9 years) in a private dental implant clinic. The implants were loaded by provisional crowns within 24 hours after surgery, and the definitive metal-ceramic crown was cemented after 3 months. A comprehensive list of factors that could influence the survival rate of implants, with all possible complications, was compiled. With this list, patient charts were retrospectively screened for possible events related to failure. The median observation time was 25.5 months. Implant survival data were evaluated using the Kaplan-Meier test, in addition to frequency counts and the Fisher Exact Test. Results: Of the 90 dental implants, 86 (95.6%) implants were still in situ. Three implants (3.3%) were lost after 1, 12 and 19 months respectively, and one implant (1.1%) lost its occlusal screw 5 months after insertion. These implants were inserted in bone of quality type II or III with a torque of more than 32Ncm to get primary stability. One lost implant was inserted with a torque less than 32Ncm and did not have primary stability. The three implants that were lost were placed in the maxilla. The implant with the lost occlusal screw was inserted in the mandible. Three of the four failed implants were Branemark System® implants, the other one was a Replace® Select implant. Due to the low failure rate, the causes of these failures are speculative, but parafunction seemed to be a risk factor. The mean survival time of the immediately loaded single-tooth implants was 18.8 months. Conclusion: This retrospective study on the success rate of immediately loaded single-tooth implants yielded a 95.6% success rate. Due to the small number of failures, no definitive conclusion can be drawn concerning the factors leading to failures of implants supporting solitary crowns. This study, nevertheless, illustrates that immediate loading of single-tooth implants is successful, and that it is a reliable treatment option to replace missing natural teeth in order to restore aestethics and/or function. Keywords: Single tooth implants, Immediately loaded single-tooth implants, Success rate, Failure and survival.
Are Husbands Involving in Birth Preparedness and Complication Readiness for their Wives’ Pregnancies?: A Cross-Sectional Study in Nay Pyi Taw, Myanmar

INTRODUCTION: Husbands’ involvement in birth preparedness and complication readiness (BP/CR) has been encouraged as a new approach to improve maternal health for safe motherhood since 2000. However, Myanmar is a patriarchy society and despite the strong domination of husbands on the health of their families, their role and involvement in maternal health are still limited. OBJECTIVE: This study aimed to assess husbands’ involvement in BP/CR for their pregnant wives in Nay Pyi Taw, Myanmar. MATERIAL AND METHODS: The research was a cross sectional study which was carried out through a structured questionnaire among 198 husbands of pregnant women aged 18 years and above in Nay Pyi Taw. RESULTS: The results showed that 42.4% of husbands included in the study had poor involvement in BP/CR for safe motherhood. Approximately 38% of husbands failed to plan health facility for delivery, 45% did not plan for a skilled birth attendant, 20% did not save money for the delivery, 43% neglected transportation arrangement and 66% did not identify a blood donor in case of emergency. Husbands having good knowledge and positive attitude were significantly (p-value <0.001) involved in BP/CR as compared to those who did not. In addition, husbands who planned the pregnancy along with wives were involved in BP/CR more than those who did not and association was significant at p<0.001. Conclusion: Level of husbands’ involvement in BP/CR is slightly low for their wives’ pregnancies. It was, therefore, recommended that effective husband involvement intervention programmes should be promoted at all levels of healthcare for safe motherhood.
Wilson Disease Comorbid with Hereditary Sensory Autonomic Neuropathy Type IV and Gitelman Syndrome

Wilson disease a rare autosomal recessive inherited disorder of copper metabolism, is characterized by excessive deposition of copper in the liver, brain, and other tissues. Wilson disease is often fatal if it is not recognized early and treated when it is symptomatic. Gitelman syndrome is also an autosomal recessive kidney disorder characterized by low blood levels of potassium and magnesium, decreased excretion of calcium in the urine, and elevated blood pH. Hereditary sensory autonomic neuropathy type IV (HSAN-IV), a very rare condition that presents in infancy, is characterized by anhidrosis, absence of pain sensation, and self-mutilation. It is usually accompanied by developmental delay and mental retardation. We report a case of Wilson disease manifested as fulminant hepatitis, acute pancreatitis, and acute kidney injury in a 15-year-old boy comorbid with HSAN-IV and Gitelman syndrome. Such concurrence of three genetic diseases is an extremely rare case.
A Review of Point Cloud Registration Algorithms for Mobile Robotics

The topic of this review is geometric registration in robotics. Registrationalgorithms associate sets of data into a common coordinate system.They have been used extensively in object reconstruction, inspection,medical application, and localization of mobile robotics. We focus onmobile robotics applications in which point clouds are to be registered.While the underlying principle of those algorithms is simple, manyvariations have been proposed for many different applications. In thisreview, we give a historical perspective of the registration problem andshow that the plethora of solutions can be organized and differentiatedaccording to a few elements. Accordingly, we present a formalizationof geometric registration and cast algorithms proposed in the literatureinto this framework. Finally, we review a few applications of thisframework in mobile robotics that cover different kinds of platforms,environments, and tasks. These examples allow us to study the specificrequirements of each use case and the necessary configuration choicesleading to the registration implementation. Ultimately, the objective ofthis review is to provide guidelines for the choice of geometric registrationconfiguration.
Neural Network Time Series: Forecasting of Financial Markets

From the Publisher: A neural network is a computer program that can recognise patterns in data, learn from this and (in the case of time series data) make forecasts of future patterns. There are now over 20 commercially available neural network programs designed for use on financial markets and there have been some notable reports of their successful application. However, like any other computer program, neural networks are only as good as the data they are given and the questions that are asked of them. Proper use of a neural network involves spending time understanding and cleaning the data: removing errors, preprocessing and postprocessing. This book takes the reader beyond the 'black-box' approach to neural networks and provides the knowledge that is required for their proper design and use in financial markets forecasting - with an emphasis on futures trading. Comprehensively specified benchmarks are provided (including weight values), drawn from time series examples in chaos theory and financial futures. The book covers data preprocessing, random walk theory, trading systems and risk analysis. It also provides a literature review, a tutorial on backpropagation, and a chapter on further reading and software. For the professional financial forecaster this book is without parallel as a comprehensive, practical and up-to-date guide to this important subject.
Correlation between precontemplation and alpha activity in gambling disorder

Purpose Gambling disorder is a psychiatric condition characterized by persistent and recurrent maladaptive gambling. In the present study, we evaluated the characteristics of resting-state electroencephalogram (EEG) recordings in patients with gambling disorder. In addition, we explored the association between the EEG characteristics of the patients and the stages of change in a transtheoretical model. Methods All participants were men who visited a gambling disorder clinic in Seoul, Korea. At the assessment, questionnaires, including the Readiness to Change Questionnaire (RCQ), were administered and resting-state EEGs were carried out. Participants were grouped based on Ward’s method for cluster analysis. Independent sample t-tests were used to evaluate group differences. To assess the relationship between the clinical data and the EEG recordings, we used Pearson’s partial correlation analysis. Results Overall, 63 male participants were enrolled. Cluster analysis of the alpha activity revealed two clusters. No significant differences were observed in the demographic or clinical data between the two groups except for the Beck Depression Inventory (BDI). We found that the precontemplation score of the RCQ was positively correlated with the z-score of the relative alpha power in almost all cortical regions. Conclusion This study suggests that EEG parameters, particularly alpha activity, could inform us about the subtypes or stages of change in gambling disorder. Alpha power is the predominant EEG rhythm in a relaxed, alert person; thus, alpha power serves as an index of relaxation. We expect that the level of alpha activity could be utilized as an additional parameter to help clinicians assess and treat patients with gambling disorder.
Validation and Verification of Multi-Steps Icing Calculation Using CANICE2D-NS Code

A newly developed Navier-Stokes based two-dimensional ice accretion and anti-icing simulation code, CANICE2D-NS is presented. The method is devised to be fully automated for use within a multi-step approach capable of analyzing long ice accretion accumulation times in a quasi-steady formulation. An efficient single-block structured Navier-Stokes CFD code, NSCODE, have been coupled with the CANICE2D icing framework, supplementing the existing panel method based flow solver. Attention is paid to the roughness implementation within the turbulence model, and to acceleration of the convergence of the steady and quasi-steady iterative procedures. Effects of uniform surface roughness in quasi-steady ice accretion simulation are analyzed through different validation test cases, including code to code comparisons with the same framework coupled with another Navier-Stokes solver. The efficiency of the J-multigrid approach to solve the flow equations on complex iced geometries is demonstrated. Finally, results on up to 160 quasi time-steps calculations are presented and analyzed. 1 Ph.D. student, kazem.hasanzadeh@polymtl.ca. 2 Postdoctoral student, ali.mosahebi@gmail.com. 3 Assistant Professor, eric.laurendeau@polymtl.ca. 4 Professor, ion.paraschivoiu@polymtl.ca.
Teleoperated Road Vehicles: A Novel Study on the Effect of Blur on Speed Perception

The future mobility of urban areas is changing constantly; ideally, vehicles should be able to drive autonomously through traffic. Unfortunately, autonomous vehicles are not yet fully capable of matching human performance. Therefore, the teleoperation of vehicles presents a solution for this task. During teleoperation, a human driver is responsible for driving the vehicle using information transmitted from the vehicle to a working station. Unfortunately, because of the artificial environment in which the operator is located, it is very difficult to achieve high telepresence and accurate speed estimation. It is known that in order to safely drive a vehicle, it is very important to be able to correctly estimate the vehicle's speed. This paper presents a study conducted to quantify the speed perception tendency of a human operator at the working station. Additionally, it is shown that a training process can at least temporarily improve speed perception. Furthermore, the implementation of zoom blur to increase optical flow is shown to positively influence speed perception. Four hypotheses are defined and analysed to study speed perception at an operator's working station. The results are presented and discussed.
A grammar of Tafi

This dissertation is a comprehensive description of Tafi, one of the fourteen Ghana-Togo Mountain (GTM) languages, spoken by approximately 4,400 people in the southeastern Ghana. The description consists of thirteen chapters and is based on a corpus gathered during two fieldwork periods totalling fifteen months in the Tafi area. The language has a nine-vowel system with root controlled Advanced Tongue Root (ATR) harmony and a complex tonology. The noun class and agreement systems display change in progress. This study also accounts for several distinctive features of the language–a small class of underived adjectives; two adpositional classes and their grammaticalization histories, and a rare split possessor system where singular possessors of kin are marked differently from other possessors; utterance particles; conversational routines; interjections, and ideophones. The form, function and meaning of serial verb constructions, split predicate constructions for some modal-aspectual meanings and a medio-passive construction for predicating properties of undergoers and topic and focus constructions are also covered. The influence of Ewe, the dominant lingua franca, on the structures in Tafi and the distinctions between Tafi and its closest neighbour Nyagbo are highlighted. A selection of glossed and translated texts– folktales, proverbs, riddles and procedural genres–is also included. The thesis is of interest to Africanists, typologists and contact linguists.
A Study on the Internal Control of Accounting Information Processing System under the Computer Environment

Since enterprises installed the computer-based accounting information system, the environment for financial accounting and accounting control therein have changed dramatically, and the accounting data processing has been accelerated. In addition, the financial accounting has witnessed great improvement in its accuracy and reliability. Meanwhile, the huge differences between the artificial accounting information processing and computer-based accounting information processing have brought new problems and challenges to the internal control. As a result, it is of great significance to study and enhance the internal control of accounting information processing system under the computer environment.
EndNote 1-2-3 Easy!: Reference Management for the Professional

Endnote Made Easy: Reference Management for the Professional is intended for healthcare professionals (physicians, nurses, managers, etc.) and biomedical researchers engaged in writing scientific manuscripts. It aids readers in gaining an understanding of the effective use of information technology in storing, managing, retrieving, and citing references in scientific writings. It also provides step by step instruction on using Endnote, a popular reference management software.
Transforming activities of the NUP98-KMT2A fusion gene associated with myelodysplasia and acute myeloid leukemia

Inv(11)(p15q23), found in myelodysplastic syndromes and acute myeloid leukemia, leads to expression of a fusion protein consisting of the N-terminal of nucleoporin 98 (NUP98) and the majority of the lysine methyltransferase 2A (KMT2A). To explore the transforming potential of this fusion we established inducible iNUP98-KMT2A transgenic mice. After a median latency of 80 weeks, over 90% of these mice developed signs of disease, with anemia and reduced bone marrow cellularity, increased white blood cell numbers, extramedullary hematopoiesis, and multilineage dysplasia. Additionally, induction of iNUP98-KMT2A led to elevated lineage marker-negative Sca-1+ c-Kit+ cell numbers in the bone marrow, which outcompeted wildtype cells in repopulation assays. Six iNUP98-KMT2A mice developed transplantable acute myeloid leukemia with leukemic blasts infiltrating multiple organs. Notably, as reported for patients, iNUP98-KMT2A leukemic blasts did not express increased levels of the HoxA-B-C gene cluster, and in contrast to KMT2A-AF9 leukemic cells, the cells were resistant to pharmacological targeting of menin and BET family proteins by MI-2-2 or JQ1, respectively. Expression of iNUP98-KMT2A in mouse embryonic fibroblasts led to an accumulation of cells in G1 phase, and abrogated replicative senescence. In bone marrow-derived hematopoietic progenitors, iNUP98-KMT2A expression similarly resulted in increased cell numbers in the G1 phase of the cell cycle, with aberrant gene expression of Sirt1, Tert, Rbl2, Twist1, Vim, and Prkcd, mimicking that seen in mouse embryonic fibroblasts. In summary, we demonstrate that iNUP98-KMT2A has in vivo transforming activity and interferes with cell cycle progression rather than primarily blocking differentiation.