Miracle-dz/UniFAR-FTUs huggingface dataset:
Cancer Incidence in Five Continents Vol. X

Africa *Algeria, Sétif 1.4 3.2 0.1 0.0 0.1 0.3 0.1 143 144 Egypt, Gharbiah 1.4 2.4 0.2 0.1 0.3 0.2 0.0 305 315 *Libya, Benghazi 1.3 2.2 0.2 0.2 0.1 51 51 *Malawi, Blantyre 2.9 1.0 0.5 0.5 1.1 0.5 69 95 *South Africa, PROMEC 0.6 0.0 0.1 0.6 − − 19 20 *Tunisia, North 1.9 4.9 0.1 0.1 0.5 0.3 0.0 562 567 *Uganda, Kyadondo County 1.5 0.4 0.3 0.2 0.8 0.0 0.1 47 71 *Zimbabwe, Harare: African 2.6 0.8 0.5 0.2 1.3 0.2 0.0 65 66 America, Central and South Argentina, Bahía Blanca 3.3 17.8 0.8 1.5 2.6 − 0.6 267 270 Argentina, Córdoba 6.2 18.7 0.4 0.1 3.6 0.1 0.6 820 835 Argentina, Mendoza 5.4 14.8 0.3 0.3 3.1 0.2 0.1 1087 1097 *Argentina, Tierra del Fuego 3.6 19.5 − − 3.0 0.3 50 50 Brazil, Aracaju 25.7 109.1 0.8 0.1 4.2 0.3 838 841 Brazil, Belo Horizonte 10.3 49.0 0.3 0.2 3.1 0.2 0.2 1645 1652 Brazil, Cuiabá 16.2 59.5 0.1 0.7 2.5 0.1 0.5 706 716 Brazil, Fortaleza 10.8 26.4 0.3 0.5 2.3 0.1 0.2 1186 1205 Brazil, Goiânia 51.8 167.8 1.8 1.2 7.8 0.5 0.3 4572 4631 *Brazil, São Paulo 19.1 72.6 0.7 1.1 5.6 0.2 − 21643 21729 Chile, Region of Antofagasta 11.9 33.9 0.7 1.2 2.0 0.1 0.3 578 583 Chile, Bío Bío Province 4.2 4.4 − − 2.3 0.1 115 117 Chile, Valdivia 3.3 11.9 0.5 0.3 3.2 0.4 205 209 Colombia, Bucaramanga 18.2 0.4 0.3 0.3 1.6 0.1 0.3 457 463 Colombia, Cali 0.0 0.4 0.1 4.0 0.1 201 205 Colombia, Manizales 5.1 − − 0.1 3.1 0.4 0.1 80 81 Colombia, Pasto 0.7 0.4 0.2 2.1 0.2 0.2 28 28 Costa Rica 10.8 32.0 0.5 0.1 2.5 0.1 0.1 4170 4374 Cuba, Villa Clara 7.6 16.8 0.5 0.1 1.6 − − 678 684 Ecuador, Cuenca 3.2 12.1 1.2 2.1 − − 163 167 Ecuador, Quito 8.3 32.1 0.2 0.4 3.5 0.0 0.
Technical note: Preliminary results with a tannin extract on the performance and mortality of growing rabbits in an enteropathy infected environment.

In 3 preliminary trials, the effect of a dietary addition with 0.5% of a chestnut tannin extract, containing approximately 55% hydrolysable tannins, was examined on mortality after weaning. The tannin-enriched diet was fed to the does and their litters from 22 days of lactation. After weaning (day 29), young rabbits did not change dietary treatment and remained on the control diet or the tannin-enriched diet, respectively. In total 1217 rabbits were considered, about half of whom were fed the tannin-enriched diet. Mortality reached 17.1% and 7.7% (trial 1, P=0.054), 17.2 and 18.2% (trail 2, NS) and 29.0% and 9.9% (trial 3, P
The constant low oxygen concentration in all the target cells for mouse tail radionecrosis.

When doses of pulsed electrons are delivered in less than 4.5 sec to the tail of the unanesthetized mouse in air at 19-23/sup 0/C, there is induced resistance to epithelial necrosis which is characteristic of oxygen depletion at high dose rates. The effect is consistent with all the target cells being constantly at about 3 to 6 . mu.M oxygen, rather than with the presence of a transiently or chronically severely hypoxic fraction of target cells. Rediffusion of oxygen takes more than 4.5 sec, and at low doses per pulse the intrapulse dose rate tends to become important. The effect of the natural hypoxia is similar when it is measured immediately after varying priming doses in air, and it persists during daily fractionation up to 15 fractions over 3 weeks.
An N-Linked Bidentate Phosphoramidite Ligand (N-Me-BIPAM) for Rhodium-Catalyzed Asymmetric 1,4-Addition of Arylboronic Acids to α,β-Unsaturated Ketones

A new bidentate phosphoramidite (N-Me-BIPAM) based on Shibasaki’s N-linked BINOL was synthesized. This ligand appears to be highly effective for rhodium-catalyzed asymmetric conjugated addition of arylboronic acids to α,β-unsaturated enones. The reaction of ortho-substituted arylboronic acid with acyclic and cyclic enones provides the corresponding products in good yields and enantioselectivities.
Job stress, sense of coherence and work wellness in an electricity supply organisation

The objective of this study was to test a causal model of work wellness for engineers, technicians and electricians in an electricity supply organisation. An ex post facto correlational design was used. The participants included 38 engineers, 86 technicians and 91 electricians in an electricity supply organisation. The Maslach Burnout Inventory – General Survey, the Utrecht Work Engagement Scale, the Job Stress Inventory and the Orientation to Life Questionnaire were administered. The results showed that job stress, because of job demands and a lack of support, leads to burnout. A strong sense of coherence mediated the relationship between job stress and work wellness (consisting of low burnout and high work engagement). The material described in this article is based upon work supported by the National Research Foundation under Grant number 2053344.
Cost‐effectiveness of ambulatory blood pressure monitoring in the follow‐up of hypertension

Aims. To study the cost of the follow‐up of hypertension in primary care (PC) using clinical blood pressure (CBP) and ambulatory blood pressure monitoring (ABPM), and to analyse the cost‐effectiveness (CE) of both methods. Major findings and principal conclusion. Good control of hypertension was achieved in 8.3% with CBP (95% CI 4.8–11.8) and in 55.6% with ABPM (95% CI 49.3–61.9). The cost of one patient with good control of hypertension is almost four times higher with CBP than with ABPM (€940 vs €238). Reaching the gold standard (ABPM) involved an after‐cost of €115 per patient. The results for a 5% discount rate showed a saving of €68,883 if ABPM was performed in all the patients included in the study (n = 241, €285 per patient). An analysis of sensitivity, changing the discount rate and life expectancy indicated that ABPM provides a better CE ratio and a lower global cost. ABPM is more cost‐effective than CBP. However, if we include the new treatment cost of poorly monitored patients, it is less cost‐effective. Excellent control of hypertension is still an important challenge for all healthcare professionals, especially for those working in PC, where most monitoring of hypertensive patients takes place.
Relationship between hepatocellular carcinoma and impaired glucose tolerance among Japanese.

BACKGROUND/AIMS Both the incidence of diabetes mellitus (DM) and mortality from Hepatocellular carcinoma (HCC) are increasing in Japan. As the association of overall cancer and HCC with impaired glucose tolerance (IGT) has been studied rarely in the world including Japan, this study assessed their associations using cohort data of Hokkaido, Japan. METHODOLOGY After getting ethical consent, this study included 908 men and 1,081 women aged 30-77 years during 1977-78 and collected detailed information using the baseline survey. The subjects were followed until 2002 and deaths were recorded using ICD-9. Classifying them into three groups of diabetes status namely DM, IGT, and normal, the relative risk (RR) of mortality was estimated by diabetes status using multivariate Cox model. RESULTS This study revealed no association between overall cancer and diabetes status. However, the RR of mortality from HCC was about 11 times (HR= 10.8, 95%CI: 1.3-92.5) higher in IGT compared with normal group. DM group also showed higher risk of mortality than normal group. CONCLUSIONS HCC mortality was significantly high among IGT group. However, as the results of the study were based on small data, further studies with large cohort are needed to address the association of IGT with overall cancer and HCC mortality in Japan.
Impact of strain engineering and channel orientation on the ESD performance of nanometer scale CMOS devices

This paper provides the first detailed insight into the effect of strain engineering on ESD performance of nano-scale ggNMOS and ggPMOS protection devices by coupling electro-thermal simulations with tight-binding bandstructure calculation, mobility modeling and thermal conductivity evaluation. The analysis reveals that apart from mobility enhancement, in the ESD domain, strain engineering plays a more promising role than that in normal device application due to bandgap engineering and minority-carrier mobility modulation. The preferential stress and channel orientations for both ggNMOS and ggPMOS are also proposed for the first time. Moreover, it is shown that while strain induced thermal properties deteriorate at high-level stress (5GPa), the ESD optimization space at such high-level stress can be extended beyond the mobility enhancement saturation region because of the positive feedback from bandgap narrowing. Finally, it is shown that the benefit of strain engineering on ESD performance improves even further with scaling.
Parents' and children's attitudes toward the enrollment of minors in genetic susceptibility research: Implications for informed consent

Purpose: Children at high risk of future disease may be recruited for participation in disease susceptibility research involving genetic testing. This study was aimed at assessing parents' and children's reactions to such research, and their perceptions of risks and benefits of participating. Methods: Parents and children (ages 10–17) from families at increased risk for breast cancer (n = 16 dyads) and heart disease (n = 21 dyads) participated in separate audiotaped interviews and a follow‐up family interview one year later. We asked about reactions, risks and benefits, and informational needs regarding participation in hypothetical research involving genetic testing on a saliva sample. Audiotape transcripts were analyzed qualitatively. Results: All children would initially participate because they viewed the research as low risk. When thinking about learning their test result and sharing it with others, or the uncertainties of testing, many children became hesitant about participating. Many parents thought their child might worry about a positive result, making them unlikely to enroll their child, or to choose not to tell the child test results. Both children and parents thought the benefits of participating included early detection or treatment (breast cancer families), prevention (heart disease families) and helping others. Children's questions about research participation centered on details of the study design and purpose, while parents' questions related to the genetic test itself. Conclusions: Children's first reaction to participating in research involving genetic susceptibility testing research may not indicate an adequate appreciation of risks and benefits; if encouraged to personalize the impact of genetic testing, children are able to engage in a more informed decision‐making process. © 2003 Wiley‐Liss, Inc.
Representation of clinical problem assessment phrases in U.S. family practice using Read version 3.1 terms: a preliminary study.

The Read Codes from the United Kingdom are a comprehensive clinical vocabulary, and one of the most likely candidates for adoption as a standard for use in Computer-Based Patient Record (CPR) systems. The new version 3.1 codes represent a major enhancement to the content and structure of the coding system, including incorporation of a new hierarchy and an explicit model for the use of qualifier terms. This is a preliminary study investigating the suitability of these codes for representing clinical problem assessment phrases in U.S. family practice. Problem assessment phrases from outpatient progress notes were encoded into the equivalent Read terms. The problem assessment phrases were evaluated for complexity and clarity. The coded representations of the phrases were evaluated for clinical acceptability. A list of coding difficulties was compiled. The most common difficulties were (1) qualifier terms present but not allowable for that Read concept (24%), and (2) qualifier terms not present (20%). British spelling and abbreviation variants were noted, but were relatively insignificant. The Read codes appear to be suitable for use in U.S. primary care practice with fairly minor modifications, but further development is required to expand the content and structure of the model for qualifier terms.
A High Performance Tandem Coupler Using Substrate Integrated Suspended Line Technology

In this letter, a tandem coupler with high performance using substrate integrated suspended line (SISL) technology is proposed. Two weekly coupled single-section coupled lines are cascaded to form the 3 dB tandem coupler. With the compensation capacitors along the coupled lines, high directivity can be obtained. Using substrate integrated suspended line technology, the proposed tandem coupler has advantages of low loss, wide bandwidth, self-packaging, low cost, light weight and easy to fabricate on conventional printed circuit board process.
The impact of influenza-associated respiratory illnesses on hospitalizations, physician visits, emergency room visits, and mortality.

OBJECTIVES Although the increased risk of hospitalization and mortality during influenza seasons has been documented extensively, there is a relative paucity of research on the impact of influenza-related illnesses on other health care use indicators, such as physician use. The purpose of this study was to examine the impact of influenza-associated respiratory illnesses on the Winnipeg health care system, including hospitalizations, physician visits and emergency room visits. Their impact on mortality was also examined. METHODS Administrative data were used to track health care use and mortality over four influenza seasons (1995-96 to 1998-99). Excess health care use and deaths were calculated by subtracting rates during influenza seasons from those during weeks when influenza viruses were not circulating. RESULTS Significant excess hospitalization, physician visit, and emergency room visit rates emerged for influenza and pneumonia, acute respiratory diseases, and chronic lung disease, especially among children and adults aged 65 and over. Considerable excess mortality due to influenza and pneumonia and chronic lung disease among individuals aged 65 and over also emerged, particularly among nursing home residents. DISCUSSION Influenza-associated respiratory illnesses have a substantial impact on the health care system. Given the burden of illness among children during influenza seasons, the study further suggests that influenza vaccination might be considered for this age group.
Accuracy of Effective Dose Estimation in Personal Dosimetry: A Comparison Between Single-badge and Double-badge Methods and the MOSFET Method

AbstractThe purpose of this study was three-fold: (1) to measure the transmission properties of various lead shielding materials, (2) to benchmark the accuracy of commercial film badge readings, and (3) to compare the accuracy of effective dose (ED) conversion factors (CF) of the U.S. Nuclear Regulatory Commission methods to the MOSFET method. The transmission properties of lead aprons and the accuracy of film badges were studied using an ion chamber and monitor. ED was determined using an adult male anthropomorphic phantom that was loaded with 20 diagnostic MOSFET detectors and scanned with a whole body CT protocol at 80, 100, and 120 kVp. One commercial film badge was placed at the collar and one at the waist. Individual organ doses and waist badge readings were corrected for lead apron attenuation. ED was computed using ICRP 103 tissue weighting factors, and ED CFs were calculated by taking the ratio of ED and badge reading. The measured single badge CFs were 0.01 (±14.9%), 0.02 (±9.49%), and 0.04 (±15.7%) for 80, 100, and 120 kVp, respectively. Current regulatory ED CF for the single badge method is 0.3; for the double-badge system, they are 0.04 (collar) and 1.5 (under lead apron at the waist). The double-badge system provides a better coefficient for the collar at 0.04; however, exposure readings under the apron are usually negligible to zero. Based on these findings, the authors recommend the use of ED CF of 0.01 for the single badge system from 80 kVp (effective energy 50.4 keV) data.
Auditory-visual integration for speech by children with and without specific language impairment.

PURPOSE It has long been known that children with specific language impairment (SLI) can demonstrate difficulty with auditory speech perception. However, speech perception can also involve the integration of both auditory and visual articulatory information. METHOD Fifty-six preschool children, half with and half without SLI, were studied in order to examine auditory-visual integration. Children watched and listened to video clips of a woman speaking [bi] and [gi]. They also listened to audio clips of [bi], [di], and [gi], produced by the same woman. The effect of visual input on speech perception was tested by presenting an auditory [bi] combined with a visually articulated [gi], which tends to alter the phoneme percept (the McGurk effect). RESULTS Both groups of children performed at ceiling when asked to identify speech tokens in auditory-only and congruent auditory-visual modalities. In the incongruent auditory-visual condition, a stronger McGurk effect was found for the normal language group compared with the children with SLI. CONCLUSION Responses by the children with SLI indicated less impact of visual processing on speech perception than was seen with their normal peers. These results demonstrate that the difficulties with speech perception by SLI children extend beyond the auditory-only modality to include auditory-visual processing as well.
Factors affecting acceptance & use of ReWIND: Validating the extended unified theory of acceptance and use of technology

Purpose – This study aims to explain the factors affecting students’ acceptance and usage of a lecture capture system (LCS) – ReWIND – in a Malaysian university based on the extended unified theory of acceptance and use of technology (UTAUT2) model. Technological advances have become an important feature of universities’ plans to improve the flexibility and accessibility in a learning and teaching environment. For private universities, which are market-driven, it is vital to assess if these technologies influence the perceptions and behaviour of their target beneficiaries. Design/methodology/approach – The study is designed using a causal research design to examine the cause–effect relationship between the study variables. The study sample consists of 398 students selected via purposive sampling. Data are collected using a five-point Likert scale covering UTAUT2’s factors and variables featuring ReWIND’s acceptance and usage. Partial least squares-based structural equation modelling is used to analyse the.
Efficacy of risperidone in reducing positive and negative symptoms in medication-refractory schizophrenia: an open prospective study.

BACKGROUND Although risperidone has been shown to be an effective antipsychotic medication in schizophrenia, the clinical studies performed for the Food and Drug Administration's approval process focused on only a mixed group of schizophrenic patients. Most of these studies did not directly address the efficacy of risperidone in chronic nonresponding schizophrenics. To better evaluate whether risperidone has a substantial degree of efficacy in schizophrenic non-responders, we conducted an open prospective study of risperidone in a sample of chronically hospitalized schizophrenic patients. METHOD Twenty-five patients who met DSM-III-R criteria for schizophrenia or schizoaffective psychosis, who were chronically hospitalized at a tertiary care state facility, and who had not responded to conventional neuroleptics were evaluated before and during treatment with risperidone by using several standard rating scales and adjunctive assessments. RESULTS Endpoint analysis showed that 36% (N = 9) of the patients were classified as responders on the basis of at least a 20% decrease in total Brief Psychiatric Rating Scale score at final evaluation. A higher percentage of patients were classified as responders when other rating scale criteria were used. Reductions in psychopathology scores were seen in scales reflecting positive symptoms but not in scores of negative symptoms. High baseline negative symptom scores were correlated with poorer response to risperidone as indicated by the decrease in positive symptom scores. CONCLUSION This study offers evidence that risperidone may reduce positive symptoms of schizophrenia for a subgroup of chronically hospitalized schizophrenic patients who have not responded to conventional neuroleptics. The comparative evaluation of the efficacy of risperidone versus that of clozapine in these types of patients requires further study.
The Ribosome-Bound Chaperones RAC and Ssb1/2p Are Required for Accurate Translation in Saccharomyces cerevisiae

ABSTRACT The chaperone homologs RAC (ribosome-associated complex) and Ssb1/2p are anchored to ribosomes; Ssb1/2p directly interacts with nascent polypeptides. The absence of RAC or Ssb1/2p results in a similar set of phenotypes, including hypersensitivity against the aminoglycoside paromomycin, which binds to the small ribosomal subunit and compromises the fidelity of translation. In order to understand this phenomenon we measured the frequency of translation termination and misincorporation in vivo and in vitro with a novel reporter system. Translational fidelity was impaired in the absence of functional RAC or Ssb1/2p, and the effect was further enhanced by paromomycin. The mutant strains suffered primarily from a defect in translation termination, while misincorporation was compromised to a lesser extent. Consistently, a low level of soluble translation termination factor Sup35p enhanced growth defects in the mutant strains. Based on the combined data we conclude that RAC and Ssb1/2p are crucial in maintaining translational fidelity beyond their postulated role as chaperones for nascent polypeptides.
A novel application of stellate ganglion block: preliminary observations for the treatment of post-traumatic stress disorder.

Across the five branches of military service, there is a common thread that binds, namely the honorable imperative to support our national security by maintaining, training, and equipping combat-ready forces. Although implementing their primary directives when called to action is an absolute necessity for securing the freedom and well-being of the general public, the realities of achieving such noble objectives bear many negative consequences for those who sacrifice their health in the process. The epidemic occurrence of the pathological anxiety condition post-traumatic stress disorder (PTSD) among combat-exposed active duty military service members and veterans is a seminal testament to the aftermath of war and the ongoing conflicts of our time. PTSD is characterized by debilitating symptoms such as intense anxiety, hyperarousal, irritability, intrusive thoughts, and sleep disturbances. The adverse consequences of PTSD are profound, resulting in high rates of suicide, depression, substance use, violence, and an inability to maintain relationships. 1 Approximately 14% to 35% of our 22.8 million U.S. veterans with a history of combat duty suffer from PTSD, a figure that far surpasses the 6.8% prevalence of PTSD among
Eruptive xanthomas associated with olanzapine use.

BACKGROUND Since their introduction to the US market, atypical antipsychotic drugs, such as olanzapine, have been widely prescribed for the management of psychosis and have increasingly been used in dermatologic settings for the treatment of psychogenic dermatoses. Mild hyperglycemia and hypertriglyceridemia have been documented from the use of these medications, but the range of effects on metabolism and the effects on skin are poorly characterized. OBSERVETION: We describe 3 patients who developed eruptive xanthomas, 1 of whom had relative insulin insufficiency, after starting olanzapine therapy. These cases further support the association of severe dyslipidemia with olanzapine use in selected patients. CONCLUSION With the increasing use of atypical antipsychotic agents in the dermatologic setting, the dyslipidemia that develops in association with olanzapine use emphasizes the need for periodic metabolic studies in high-risk patients.