Miracle-dz/UniFAR-FTUs huggingface dataset:
The social construction of academic success of learning disabled college students

Robin D. Waltman THE SOCIAL CONSTRUCTION OF ACADEMIC SUCCESS OF LEARNING DISABLED COLLEGE STUDENTS 2002/03 Dr. John Klanderman and Dr. Roberta Dihoff Master of Arts in School Psychology The purpose of this study was to examine the challenges faced by college students with learning disabilities from their own perspective. Interviews were conducted with four first-year students with learning disabilities and five sophomore, junior, and senior students with learning disabilities. The subjects attended Rowan University in Glassboro, New Jersey. The subjects were varied in race, socioeconomic backgrounds, and majors. They all attended college full-time. Qualitative data analysis was performed in order to construct thematic categories from recurring patterns. It was found that college students with learning disabilities have difficulties in college that are unique. They not only have academic difficulties, they also have social difficulties and they lack the support systems necessary to succeed. Many of the subjects did not have enriching academic experiences as children. Because of this, they find the college transition challenging. It was found that the single most important aspect to the success of these students was support by parents and faculty members.
Kirznerian and Schumpeterian entrepreneurship in Trinidad and Tobago

Purpose This paper aims to highlight the possibility that the same cultural and/or institutional environment can differentially affect each of the two moments of entrepreneurship – opportunity identification and opportunity exploitation. It is possible that the cultural and institutional environment in a particular place may encourage opportunity identification, but discourage opportunity exploitation, or vice versa. Specifically, this paper argues that understanding entrepreneurship in Trinidad and Tobago requires that we focus on how Trinidadian culture and institutions differentially affect both moments of entrepreneurship. Design/methodology/approach To examine how Trinidad and Tobago’s culture and institutions affect entrepreneurial opportunity identification and exploitation in that country, the paper uses a qualitative approach. In total, 25 subjects agreed to interviews, conducted in July and August 2009 in Trinidad. The questions were geared at understanding attitudes toward work and entrepreneurship in Trinidad, and how politics, culture and ethnicity interacted with those attitudes. The paper also examined institutional indicators from the Economic Freedom of the World: 2013 Annual Report and the World Bank’s 2016 Doing Business Report. Findings The research identified features of the cultural and institutional environment in Trinidad and Tobago that help to explain why opportunity identification is relatively common among all ethnic groups there, but why opportunity exploitation appears relatively suppressed among African–Trinidadians. In particular, the research finds that the inheritance of British institutions, a post-colonial political culture, a post-colonial business culture and ethnically based social networks all have positive and negative influences on each moment of entrepreneurship. Research limitations/implications Further research would involve an analysis of a wider set of both formal and informal entrepreneurial activities in Trinidad and Tobago, across industries and periods. Practical implications This paper has implications for understanding the complex nature of entrepreneurship, which many policymakers try to encourage, but which is shaped by deep cultural and historical factors, and also indirectly influenced by state policies and laws. Social implications Ethnic patterns in entrepreneurship shape the way groups see themselves and others. Originality/value While authors writing about opportunity recognition/identification and opportunity exploitation have captured the important dimensions of entrepreneurship, they underestimate the possibility of a disconnect between entrepreneurial identification and exploitation. Focusing on instances where the disconnect exists allows us to move away from characterizations of cultures as progress-prone or progress-resistant, and instead allows us to focus on these gaps between identifying and exploiting entrepreneurship across cultures.
On the direct determination of reflectivity spectrum from synthetic aperture radar data

A method for obtaining the Fourier transform of a synthetic aperture radar reflectivity map is described where the reflectivity map itself does not need to be produced from the radar data. The procedure essentially rearranges a sequence of numerical integrations in such a manner that allows one or more numerical integration to be replaced by a closed-form expression involving Fresnel integrals. >
Pyrethroid resistance in
 Culex quinquefasciatus
 from West Africa

Laboratoire de Lutte contre les Insectes Nuisibles, ORSTOM, Montpellier, France, *OCCGE, Institut Pierre Richet, BP 1500, Bouaké 01, Côte d'Ivoire, †INRA, Laboratoire de Biologie des Invertébrés, 123 Bd Meilland, 06606 Antibes, France, and ‡CNRS UMR 5554, Laboratoire de Génétique et Environnement, Institut des Sciences de l'Environnement, Université de Montpellier II (CC 065), 34095 Montpellier, France
Quantification of Motor Impairment in Parkinson's Disease Using an Instrumented Timed Up and Go Test

The Timed Up and Go (TUG) test is a clinical test to assess mobility in Parkinson's disease (PD). It consists of rising from a chair, walking, turning, and sitting. Its total duration is the traditional clinical outcome. In this study an instrumented TUG (iTUG) was used to supplement the quantitative information about the TUG performance of PD subjects: a single accelerometer, worn at the lower back, was used to record the acceleration signals during the test and acceleration-derived measures were extracted from the recorded signals. The aim was to select reliable measures to identify and quantify the differences between the motor patterns of healthy and PD subjects; in order to do so, besides comparing each measure individually to find significant group differences, feature selection and classification were used to identify the distinctive motor pattern of PD subjects. A subset of three features (two from Turning, one from the Sit-to-Walk component), combined with an easily-interpretable classifier (Linear Discriminant Analysis), was found to have the best accuracy in discriminating between healthy and early-mild PD subjects. These results suggest that the proposed iTUG can characterize PD motor impairment and, hence, may be used for evaluation, and, prospectively, follow-up, and monitoring of disease progression.
Reconstruction of gluteal deformities: a systematic review and experience of four cases

Abstract Background: The reconstruction of gluteal deformities remains a major challenge. The aim of this article is to provide a systematic review of the literature concerned, and to present a case series with representative defects from various zones. Methods: A review of the literature was performed using PubMed, EMBASE, and The Cochrane Library, in accordance with the PRISMA statement. Quality of evidence was rated according to GRADE. Patients with various buttock deformities were included and, depending on the defect, the reconstructive techniques applied consisted of lipoinjection, local fasciocutaneous flap, or pedicled gracilis muscle flap. Complications, patient’s pain assessment, impairment in everyday-life activities, aesthetic outcome, objective assessment of sensitivity, and recurrence were considered. Results: A total of 498 records were identified in the literature search. Of those, 12 studies met the PICOS (participants, interventions, comparators, outcomes, and study design) criteria. Overall, 41 patients were analysed, the evidence of which was of low quality. In this study, four patients (three female and one male) with a mean age of 44 ± 15 years were operated on between 2010–2014. The mean operation time was 83 ± 30 minutes. One patient required revision due to persistent seroma and recurrence, and one patient required neurolysis and gracilis denervation due to neuroma and scarring. After a mean follow-up of 40 ± 21 months, the results were functionally and cosmetically satisfactory. Conclusions: Reconstruction of buttock deformities using an integrated approach can lead to a long-lasting, functionally and aesthetically satisfactory result. However, evidence is limited due to the lack of good-quality studies.
Physiological Factors Associated With Declining Repeated Sprint Performance in Hypoxia

Abstract Gatterer, H, Menz, V, Untersteiner, C, Klarod, K, and Burtscher, M. Physiological factors associated with declining repeated sprint performance in hypoxia. J Strength Cond Res 33(1): 211–216, 2019—Performance loss in hypoxia might not only be caused by reduced oxygen availability, but might also be influenced by other factors, as for example, oxidative stress, perceived exertion, or breathing patterns. This study aimed to investigate the influence of these factors on running performance during hypoxic and normoxic shuttle-run sprinting. Eight male amateur soccer players performed shuttle-run sprints in hypoxia (FiO2 ∼14.8%) and normoxia (random order). Each session comprized 3 sets of 5 × 10 seconds back and forth sprints (4.5 m), with recovery times between repetitions and sets of 20 seconds and 5 minutes, respectively. Sprinting distance, acceleration patterns, heart rate (HR) and breathing frequency were measured during each session (Zephyr-PSM Training System). Redox state and lactate concentration ([La]) were determined before and after each session, whereas rating of perceived exertion (RPE) was assessed after the sprint sessions. Overall distance covered was similar during hypoxia and normoxia sprinting (&Dgr; −8.3 ± 14.3 m, 95% CI −20.2 to 3.6, p > 0.05). During the third set, distance tended to be reduced in hypoxia compared with normoxia (169 ± 6 m, 95% CI 164–174 vs. 175 ± 4 m, 95% CI 171–178, p = 0.070). Differences in breathing frequency during sprinting in hypoxia and normoxia were associated with individual reductions in sprinting distance (r = −0.792, p = 0.019). Despite a somewhat lower running distance during the third set and similar [La], RPE, HR, and redox responses, the preserved overall running distance indicates that the training stimulus might be enhanced in hypoxia compared with normoxia. Alteration of the respiratory patterns during repeated sprinting in hypoxia might be one factor, besides others, responsible for a potential performance loss. It could be hypothesized that respiratory pattern adaptations are involved in potential performance improvements after hypoxia repeated sprint training.
An Experimental Study of Incentive Reversal in Sequential and Simultaneous Games

I t is commonly held that increasing monetary rewards enhance work effort. This study, however, argues that this will not ineludibly occur in team activities. Incentive Reversal may occur in sequential team productions featuring positive external impacts on agents. This seemingly paradoxical event is explained through two experiments in this article. The first experiment involves a sample of 182 college students who were paired in groups each playing 12 games that led to 2,184 observations. The second experiment involves a sample of 210 college students who were grouped into teams of three that involved 420 observations. The results of both experiments confirmed the occurrence of incentive reversals despite increasing monetary rewards.
Spatio-Temporal Dynamics of Hypoxia during Radiotherapy

Tumour hypoxia plays a pivotal role in cancer therapy for most therapeutic approaches from radiotherapy to immunotherapy. The detailed and accurate knowledge of the oxygen distribution in a tumour is necessary in order to determine the right treatment strategy. Still, due to the limited spatial and temporal resolution of imaging methods as well as lacking fundamental understanding of internal oxygenation dynamics in tumours, the precise oxygen distribution map is rarely available for treatment planing. We employ an agent-based in silico tumour spheroid model in order to study the complex, localized and fast oxygen dynamics in tumour micro-regions which are induced by radiotherapy. A lattice-free, 3D, agent-based approach for cell representation is coupled with a high-resolution diffusion solver that includes a tissue density-dependent diffusion coefficient. This allows us to assess the space- and time-resolved reoxygenation response of a small subvolume of tumour tissue in response to radiotherapy. In response to irradiation the tumour nodule exhibits characteristic reoxygenation and re-depletion dynamics which we resolve with high spatio-temporal resolution. The reoxygenation follows specific timings, which should be respected in treatment in order to maximise the use of the oxygen enhancement effects. Oxygen dynamics within the tumour create windows of opportunity for the use of adjuvant chemotherapeutica and hypoxia-activated drugs. Overall, we show that by using modelling it is possible to follow the oxygenation dynamics beyond common resolution limits and predict beneficial strategies for therapy and in vitro verification. Models of cell cycle and oxygen dynamics in tumours should in the future be combined with imaging techniques, to allow for a systematic experimental study of possible improved schedules and to ultimately extend the reach of oxygenation monitoring available in clinical treatment.
The social legitimacy of targeted welfare: Attitudes to welfare deservingness

This book addresses new perspectives on the perceived popular deservingness of target groups of social services and benefits, offering new insights and analysis to this quickly developing field of welfare attitudes research. It provides an up-to-date state of the art in terms of concepts, theories, research methods and data. The book offers a multi-disciplinary view on deservingness attitudes, with contributions from sociology, political science, media studies and social psychology. It links up with central welfare state debates about the allocation of collective resources between groups with particular needs, and wider categories of need.
Development of contour integration in macaque monkeys

Studies of visual development show that basic metrics of visual development such as spatial resolution develop over the first 6–9 months in monkeys and over the first 6 or so years in humans. However, more complex visual functions may develop over different, or more protracted, time courses. To address the question of whether global perceptual processing is linked to or otherwise dependent on the development of basic spatial vision, we studied the development of contour integration, a global perceptual task, in comparison to that of grating acuity in macaque monkeys. We find that contour integration develops substantially later than acuity. Contour integration begins to develop at 5–6 months, near the time that acuity development is complete and continues to mature well into the second postnatal year. We discuss this later development in terms poor central efficiency and consider the relevant anatomy and physiology of the developing visual system. We conclude that contour integration is not likely to be limited by the same mechanisms that are permissive to acuity development, and may instead reflect the emergence of function central to V1.
Predicting Perceived Brand Personality with Social Media

Brand personality has been shown to affect a variety of user behaviors such as individual preferences and social interactions. Despite intensive research efforts in human personality assessment, little is known about brand personality and its relationship with social media. Leveraging the theory in marketing, we analyze how brand personality associates with its contributing factors embodied in social media. Based on the analysis of over 10K survey responses and a large corpus of social media data from 219 brands, we quantify the relative importance of factors driving brand personality. The brand personality model developed with social media data achieves predicted R2 values as high as 0.67. We conclude by illustrating how modeling brand personality can help users find brands suiting their personal characteristics and help companies manage brand perceptions.
High sustained virological response rate to combination therapy in genotype 1 patients with histologically mild hepatitis C.

BACKGROUND Patients with mild hepatitis C have a significant risk of disease progression at medium- and long-term follow-up and should be considered for antiviral therapy. AIM To evaluate the rate of sustained viral response (SVR) and predictive factors of SVR in HCV genotype 1 patients with mild hepatitis C (fibrosis stage F0/F1) treated with combination antiviral therapy. METHODS 260 naïve patients were followed-up during 72 weeks in three referral hepatology centers between 2004 and 2006. Univariate and multivariate logistic regression analysis was conducted. RESULTS Early virological response was 88.1% and SVR was 74.2%. In the univariate analysis, SVR was associated with young age (p=0.001), very low (< or = 400,000 IU/mL) baseline viremia (p=0.03) and high aminotransferase levels (p=0.04) and was not associated with gender, body mass index, inflammatory activity, steatosis, ribavirin and peginterferon dose changes, premature cessation of therapy. Multivariate analysis identified the following independent predictors of SVR: age <50 years (p=0.0009), viral load < or = 400,000 IU/mL (p=0.03) and aminotransferase level >2 times normal value (p=0.02). CONCLUSIONS Genotype 1 HCV patients with mild hepatitis have a high rate of SVR, similar to genotype non-1. Young age, very low viremia and significant hepatocytolisis are independent predictors of SVR in patients with mild hepatitis.
Green Customer Behavior on Eco-Friendly Products: Innovation Approach

This aim of the study investigates the correlation of perceived innovation, service innovation and green perceived value on eco-friendly products, to improve customer decision of product with moderation of sex and educational background. The study of eco-friendly product has been common in the world. Indonesia is a country which is not very good at circulation of eco-friendly product. The study is conducted with focuses on eco-friendly products; through experiment survey to customer who has bought eco-friendly products in Bandung city. The research found that perceived innovation, service innovation and green perceived value have correlation. However green perceived value as based of purchase decision of customer can only be improved by perceived innovation of eco-friendly products. Furthermore, sex and customer’s educational background can truly support the correlation of perceived innovation with green perceived value of customer. This research finding explained how important perceived innovation supported by the characteristics (sex, educational background) of customers.
Pressure-Induced Differential Regulation of the Two Tryptophan Permeases Tat1 and Tat2 by Ubiquitin Ligase Rsp5 and Its Binding Proteins, Bul1 and Bul2

ABSTRACT Tryptophan uptake appears to be the Achilles' heel in yeast physiology, since under a variety of seemingly diverse toxic conditions, it becomes the limiting factor for cell growth. When growing cells of Saccharomyces cerevisiae are subjected to high hydrostatic pressure, tryptophan uptake is down-regulated, leading to cell cycle arrest in the G1 phase. Here we present evidence that the two tryptophan permeases Tat1 and Tat2 are differentially regulated by Rsp5 ubiquitin ligase in response to high hydrostatic pressure. Analysis of high-pressure growth mutants revealed that the HPG1 gene was allelic to RSP5. The HPG1 mutation or the bul1Δ bul2Δ double mutation caused a marked increase in the steady-state level of Tat2 but not of Tat1, although both permeases were degraded at high pressure in an Rsp5-dependent manner. There were marked differences in subcellular localization. Tat1 localized predominantly in the plasma membrane, whereas Tat2 was abundant in the internal membranes. Moreover, Tat1 was associated with lipid rafts, whereas Tat2 localized in bulk lipids. Surprisingly, Tat2 became associated with lipid rafts upon the occurrence of a ubiquitination defect. These results suggest that ubiquitination is an important determinant of the localization and regulation of these tryptophan permeases. Determination of the activation volume (ΔV≠) for Tat1- and Tat2-mediated tryptophan uptake (89.3 and 50.8 ml/mol, respectively) revealed that both permeases are highly sensitive to membrane perturbation and that Tat1 rather than Tat2 is likely to undergo a dramatic conformational change during tryptophan import. We suggest that hydrostatic pressure is a unique tool for elucidating the dynamics of integral membrane protein functions as well as for probing lipid microenvironments where they localize.
Dissection of Membrane Dynamics of the ARF‐Guanine Nucleotide Exchange Factor GBF1

ADP‐ribosylation factor (ARF)‐facilitated recruitment of COP I to membranes is required for secretory traffic. The guanine nucleotide exchange factor GBF1 activates ARF and regulates ARF/COP I dynamics at the endoplasmic reticulum (ER)–Golgi interface. Like ARF and coatomer, GBF1 peripherally associates with membranes. ADP‐ribosylation factor and coatomer have been shown to rapidly cycle between membranes and cytosol, but the membrane dynamics of GBF1 are unknown. Here, we used fluorescence recovery after photobleaching to characterize the behavior of GFP‐tagged GBF1. We report that GBF1 rapidly cycles between membranes and the cytosol (t1/2 is approximately 17 ± 1 seconds). GBF1 cycles faster than GFP‐tagged ARF, suggesting that in each round of association/dissociation, GBF1 catalyzes a single event of ARF activation, and that the activated ARF remains on membrane after GBF1 dissociation. Using three different approaches [expression of an inactive (E794K) GBF1 mutant, expression of the ARF1 (T31N) mutant with decreased affinity for GTP and Brefeldin A treatment], we show that GBF1 is stabilized on membranes when in a complex with ARF–GDP. GBF1 dissociation from ARF and membranes is triggered by its catalytic activity, i.e. the displacement of GDP and the subsequent binding of GTP to ARF. Our findings imply that continuous cycles of recruitment and dissociation of GBF1 to membranes are required for sustained ARF activation and COP I recruitment that underlies ER‐Golgi traffic.
Chemiluminescent Analysis of Gene Expression on High-density Filter Arrays

We have optimized conditions for the chemiluminescent analysis of gene expression using high-density filter arrays (HDFAs). High sensitivity and specificity were achieved by optimizing cDNA probe synthesis, hybridization, and detection parameters. The chemiluminescent expression profile reflected expected differences in the transcripts isolated from different sources (placenta and keratinocytes). We estimated the detection limit for low-abundance message to be 1-15 transcripts per cell, a sensitivity rivaling that reported for microarray formats and exceeding that reported for autoradiographic HDFAs. The method allows for short exposure times and reuse of probe. It should be equally applicable to techniques such as differential screening of cDNA libraries and differential display PCR.