Miracle-dz/UniFAR-FTUs huggingface dataset:
"Good enough" nanny : socioeconomic disparity and power in the nanny-employer dyad

Because nannies are typically of lower socioeconomic status than their employers, unique power dynamics develop in the relationships between parents and secondary caregivers. This empirical study explored childcare providers’ experiences of these dynamics by examining how similarity and difference in the nanny-employer dyad impacted the employer’s management style. Sample. The quantitative, exploratory method utilized an anonymous online questionnaire to reach a broad sample of current and former nannies (N=167). Methods. Demographic data on participants’ and employers’ socioeconomic identities were collected and compared with management style indicators. Findings. The results suggested that similarity and difference in the dyad, both relational and socioeconomic, impact nannies’ experiences of their employers’ management strategies. Participants who perceived themselves as similar to their employers experienced more autonomy and less surveillance at work, received better compensation, and were more likely to work for very wealthy employers. Nannies who experienced more surveillance and less autonomy tended to be those who spent more time with children over a long employment term, and those whose education level was similar to that of their employers. Winnicott's (1953) theory of object usage and Benjamin's (1988) theory of intersubjective recognition were applied to the findings to explore the implications for internal object relationships in the nanny-employer dyad. Relevance to clinical social work was also discussed. ‘GOOD ENOUGH’ NANNY: SOCIOECONOMIC DISPARITY & POWER IN THE NANNY-EMPLOYER DYAD A project based upon independent investigation, submitted in partial fulfillment of the requirements for the degree of Master of Social Work.
Toward 90-90-90: identifying those who have never been tested for HIV and differences by sex in Lesotho

ABSTRACT To reach HIV epidemic control it is important to ensure that those who have never been tested access HIV testing and counseling (HTC) particularly in the context of a generalized HIV epidemic. Using data from the 2014 Lesotho Demographic Health Survey bivariate and multivariate logistic regressions were conducted to determine the associations between never tested for HIV and key socio-cognitive characteristics by sex. Marginal probabilities at the means were calculated for the socio-cognitive variables for men and women to ascertain the magnitude of the differences in the likelihood of never being tested by sex. We stratified by gender and controlled for age, education, religion, marital status, place of residence, and years circumcised (for men only). Results indicate that more men than women have never been tested (χ2 = 461.16, p < 0.001); and, among men, acceptance of gender based violence (Odds ratio [OR]: 1.44, p < 0.001), holding discriminatory attitudes (OR: 1.50, p < 0.001), and not having basic HIV prevention knowledge (OR: 1.53, p < 0.001) were significantly associated with never being tested. The likelihood of never being tested among those who had these three socio-cognitive characteristics was much higher among men (0.56, p < 0.001) than women (0.20, p < 0.001). Given the strong sex differential, there is an urgent need for strategies specifically targeting men in order to effectively promote HTC uptake among them. Additionally, results suggest that those strategies should integrate strategies to address GBV acceptance, HIV prevention knowledge, and HIV discrimination or link men to programs addressing these.
Yersinia Ysc‐Yop type III secretion feedback inhibition is relieved through YscV‐dependent recognition and secretion of LcrQ

Human pathogenic Yersinia species share a virulence plasmid encoding the Ysc‐Yop type III secretion system (T3SS). A plasmid‐encoded anti‐activator, LcrQ, negatively regulates the expression of this secretion system. Under inducible conditions, LcrQ is secreted outside of bacterial cells and this activates the T3SS, but the mechanism of targeting LcrQ for type III secretion remains largely unknown. In this study, we characterized the regulatory role of the export apparatus component YscV. Depletion or overexpression of YscV compromised Yop synthesis and this primarily prevented secretion of LcrQ. It followed that a lcrQ deletion reversed the repressive effects of excessive YscV. Further characterization demonstrated that the YscV residues 493–511 located within the C‐terminal soluble cytoplasmic domain directly bound with LcrQ. Critically, YscV‐LcrQ complex formation was a requirement for LcrQ secretion, since YscVΔ493–511 failed to secrete LcrQ. This forced a cytoplasmic accumulation of LcrQ, which predictably caused the feedback inhibition of Yops synthesis. Based on these observations, we proposed a model for the YscV‐dependent secretion of LcrQ and its role in regulating Yop synthesis in Yersinia.
A novel keratan sulphate proteoglycan from a human embryonal carcinoma cell line.

We describe here the purification and partial characterization of a 200 kDa keratan sulphate proteoglycan found in the pericellular matrix of human embryonal carcinoma cells. Previously we have shown that this molecule is recognized by a monoclonal antibody (GCTM-2). The antigen was isolated using ion-exchange chromatography and gel filtration, purification being monitored by e.l. i.s. a. using GCTM-2. Metabolic labelling of GCT 27 C-4 embryonal carcinoma cells with sodium [35S]sulphate resulted in the incorporation of [35S]sulphate into the purified molecule. Throughout the purification procedure, the peaks of 35S radioactivity were coincident with the peaks of immunoreactivity, and this label was released both by digestion with keratanase and chondroitinase, confirming the proteoglycan nature of the antigen. The intact molecule ran as a single broad band of 200 kDa, which has been identified by silver staining and immunoblotting following gel electrophoresis. Amino acid analysis of the purified antigen indicated a high content of serine, glycine and aspartic acid/asparagine residues. Visualization by rotary-shadowing electron microscopy suggests that the purified material forms large aggregates, even under denaturing conditions. Deglycosylation of this preparation with trifluoromethanesulphonic acid yielded a major band of 55 kDa and a minor band of 48 kDa. The biochemical nature of the molecule described here, along with tissue distribution studies using GCTM-2, indicates that the antigen is not related to previously described keratan sulphate proteoglycans.
Corporate governance structures and firm performance in large agriculture companies in New Zealand

PurposeThis study aims to explore the role of corporate governance (CG) characteristics on the financial performance of large agricultural companies in New Zealand. External auditor remuneration and board characteristics, such as board ownership, board compensation, board independence and board gender diversity, are addressed in the context of New Zealand’s agricultural companies by applying agency theory.Design/methodology/approachThis paper uses a balanced panel data generalised least square regression analysis on 80 firm-years of observations over the period from 2012 to 2015.FindingsEmpirical analysis revealed that external auditors’ remuneration and board characteristics, such as board compensation and board independence, except for board ownership and board gender diversity, held no association with the agricultural companies’ performance. While board ownership and board gender diversity were negatively, but significantly, associated with firm performance, these results were pronounced in the listed agricultural companies rather than in the non-listed companies.Research limitations/implicationsThis study encountered limitations commonly associated with the majority of industry-specific studies, i.e. small sample size and lack of published financial information from databases. Therefore, for generalisation, these limitations were considered relevant.Practical implicationsThe results of this research project are beneficial for authorities and agricultural company directors in implementing CG principles and guidelines to empower such companies in international competition. Encouraging agricultural companies to maintain a high level of transparency in financial reporting is of central interest for the government’s economic development, and stock market investors achieve a high level of transparency in non-financial disclosures, the chief objective of this study. Finally, the results of this paper may encourage auditors to scrutinise CG disclosures by agricultural companies in more detail, looking for undisclosed information.Social implicationsThe results of this paper may encourage managerial transparency by providing appropriate disclosures for the public benefit. Investors may benefit from the disclosure provided in their economic decision-making and the public may expand on the information disclosed in facilitating development through exports, expansion of foreign investments and the indigenous economy.Originality/valueThe findings contribute to the literature by providing novel and original insights into using a sample of listed and non-listed agricultural companies to extend the current understanding of the governance-performance nexus.
Linking Clauses and Actions in Social Interaction

This volume concerns the ways in which verbal and non-verbal actions are combined and linked in a range of contexts in everyday conversation, in institutional contexts, and in written journalism. The volume includes an introduction which, besides presenting the content of the articles, discusses terminological fundamentals such as the understanding of the terms “clause”, “action” and “linkage” and “combining” in different grammatical traditions and the ways they are conceived of here, as well as open questions collectively formulated by the contributors in planning for the volume concerning the recognition, emergence and distance of linkage, and the ways these questions are addressed in the contributions to the volume. Topics treated in the articles include combining physical actions and verbal announcements in everyday conversation, linking of verbal and nonverbal actions as well as verbal linkages between nonverbal actions by dance teachers building pedagogical activity. Other topics concern the mediation of questions through informal translating in multilingual conversation in order to organize participation, and the ways in which student requests for clarification and confirmation create learning occasions in a foreign language classroom. Still other articles concern the on-line emergence of alternative questions with the Finnish particle vai 'or', delayed completions of unfinished turns, the transforming of requests and offers into joint ventures, and the ways in which direct quotations are created in written journalism from the original talk in the spoken interview. Most of the papers employ Conversation Analysis and Interactional Linguistics as a theoretical framework. The languages used as data are Finnish, English, Estonian, French, Brazilian Portuguese and Swedish.
Nursing in media-saturated societies: implications for cultural safety in nursing practice in Aotearoa New Zealand

This educational piece seeks to apprise nurses and other health professionals of mass media news practices that distort social and health policy development. It focuses on two media discourses evident in White settler societies, primarily Australia, Canada, New Zealand and the United States, drawing out implications of these media practices for those committed to social justice and health equity. The first discourse masks the dominant culture, ensuring it is not readily recognised as a culture, naturalising the dominant values, practices and institutions, and rendering their cultural foundations invisible. The second discourse represents indigenous peoples and minority ethnic groups as ‘raced’ – portrayed in ways that marginalise their culture and disparage them as peoples. Grounded in media research from different societies, the paper focuses on the implications for New Zealand nurses and their ability to practise in a culturally safe manner as an exemplary case. It is imperative that these findings are elaborated for New Zealand and that nurses and other health professionals extend the work in relation to practice in their own society.
Autologous peripheral stem cell transplantation of the blastic phase of chronic myeloid leukemia following sequential high‐dose cytosine arabinoside and melphalan

Blast‐phase chronic myelogenous leukemia (CML) is the terminal phase in CML and is uniformly fatal. We treated 12 patients with blast‐phase CML with a program of high‐dose cytarabine 3.0 g/m2 and melphalan 140 mg/m2. followed by reinfusion of stem cells obtained from peripheral blood during the chronic phase.
Effect of HELP‐LDL‐apheresis on serum concentrations of human lipoprotein(a): kinetic analysis of the post‐treatment return to baseline levels

Abstract. In addition to LDL, Lp(a) can be quantitavely eliminated from plasma in an extracorporeal LDL‐apheresis procedure based on precipitation with heparin at pH 5.12. The rates of return of postapheresis Lp(a) and LDL‐cholesterol concentrations to baseline levels were investigated in six individuals with familial hypercholesterolaemia (one homozygote, five heterozygote) and one normolipaemic individual. The first‐order disappearance constants (k) were derived for LDL and Lp(a) according to Apstein et al. [1]. The k values for LDL in the homozygous FH and the normolipaemic individual were 0.082 and 0.43 respectively while the heterozygous FH patients had k values intermediate between the two (median 0.231; range 0.116–0.261). The first‐order disappearance constants of Lp(a) did not correlate with those of LDL. The homozygous FH and normolipaemic individuals had Lp(a) k values of 0.158 and 0.199 respectively; the corresponding values in the heterozygous FH patients were: median 0.142; range 0.045–0.179.
Control of sleep-to-wake transitions via fast amino acid and slow neuropeptide transmission

The locus coeruleus (LC) modulates cortical, subcortical, cerebellar, brainstem and spinal cord circuits and it expresses receptors for neuromodulators that operate on a time scale of several seconds. Evidence from anatomical, electrophysiological and optogenetic experiments has shown that LC neurons receive input from a group of neurons called hypocretin neurons that release a neuropeptide called hypocretin. It is less well known how these two groups of neurons can be coregulated using GABAergic (GABA standing for gamma aminobutyric acid) neurons. As the time scale for GABAA inhibition is several orders of magnitude faster than that for the hypocretin neuropeptide effect, we investigate the limits of circuit activity regulation using a realistic model of neurons. Our investigation shows that GABAA inhibition is insufficient to control the activity levels of the LCs. Although slower forms of GABAA can in principle work, there is not much plausibility due to the low probability of the presence of slow GABAA and lack of robust stability at the maximum firing frequencies. The best possible control mechanism predicted by our modeling analysis is the presence of inhibitory neuropeptides, which exert effects on a similar time scale to the hypocretin/orexin. Although the nature of these inhibitory neuropeptides has not been identified yet, it provides the most efficient mechanism in the modeling analysis. Finally, we present a reduced mean-field model that perfectly captures the dynamics and the phenomena generated by this circuit. This investigation shows that brain communication involving multiple time scales can be better controlled by employing orthogonal mechanisms of neural transmission to decrease interference between cognitive processes and hypothalamic functions.
Positive Affectivity Is Dampened in Youths With Histories of Major Depression and Their Never-Depressed Adolescent Siblings

Although hedonic capacity is diminished during clinical depression, it is unclear whether that deficit constitutes a risk factor or persists after depression episodes remit. To examine these issues, adolescents with current/past major depression (probands; n = 218), never-depressed biological siblings of probands (n = 207), and emotionally well controls (n = 183) were exposed to several positively valenced probes. Across baseline and hedonic probe conditions, controls consistently reported higher levels of positive affect than high-risk siblings, and siblings reported higher levels of positive affect than probands (remitted and depressed probands’ reports were similar). Extent of positive affect across the protocol predicted adolescents’ self-reports of social support network and parental reports of offspring’s use of various adaptive mood repair responses in daily life. Attenuated hedonic responding among youths remitted from depression offers partial support for anhedonia as a trait, whereas its presence among never-depressed high-risk siblings argues for anhedonia as a potential diathesis for clinical depression.
Asset Specificity and Conditional Accounting Conservatism

Asset specificity, the redeployability of an asset to alternative uses, is a key determinant of an asset's resale value. Asset specificity has a direct impact on a firm's ongoing fair value determination, bankruptcy risk, liquidation value, and abandonment option. We document a significant negative association between asset specificity and conditional conservatism. Further tests reveal that this inverse relation manifests as bad news being less quickly incorporated in earnings as asset specificity increases. We find no difference in the extent to which good news is delayed in earnings for firms conditional on asset specificity. In addition, the documented association is stronger when asset specificity arises from lower within‐industry acquisition activity. The association is also more pronounced for firms that are in less competitive industries, have institutional investors, have limited access to the public debt market, and/or have more unsecured debt. Our findings are noteworthy for regulators and researchers given the recent interest in the determinants of conservatism.
Thyrotropin-releasing hormone immunoreactivity in human blood, urine, spinal fluid, amniotic fluid, saliva, and gastric juice.

TRH immunoreactivity levels were measured in human blood, urine, saliva, spinal fluid, amniotic fluid and gastric juice. Urinary TRH excretion during a 48-h period was measured in 11 healthy persons. Blood and urinary TRH immunoreactivity were measured at 2 and 5 h, respectively, after administration of 40 mg of TRH. All the samples were prepurified by SP-Sephadex-C-25 cation-exchange chromatography and subjected to reverse-phase high-pressure liquid chromatography (HPLC). TRH immunoreactivity levels were then measured by our TRH radioimmunoassay. The TRH immunoreactivity (TRH-ir) levels found in urine were 14.6 +/- 2.5 pmol/l; in blood 7.5 +/- 2.0 pmol/l; in spinal fluid 2.8 +/- 1.4 pmol/l, and in gastric juice 23.2 +/- 7.1 pmol/l. In all of the amniotic fluid and saliva samples, in almost one half of the blood and spinal fluid samples, and in almost one third of the gastric juice samples, TRH-ir was below the detectable limit. In blood and urine samples taken after oral administration of TRH, TRH-ir was eluted at the same time as synthetic TRH. The recovery of synthetic TRH added to the samples ranged from 36 to 99%. In all of the biological fluid samples, endogenous TRH-ir was eluted at the same time in HPLC, at 15-18 min, as was synthetic TRH which had been added to the samples. Urine was found to contain two TRH immunoreactive peaks, the second of which was eluted at the same time as synthetic TRH. No diurnal variation in urinary TRH excretion or TRH-ir levels was found. (ABSTRACT TRUNCATED AT 250 WORDS)
Risk of travel-associated typhoid and paratyphoid fevers in various regions.

BACKGROUND Although enteric fever (typhoid and paratyphoid fevers) is a major global public health problem, comparable data on the risks of contracting travel-associated enteric fever in various regions of the world are scarce. METHODS From the Swedish database on notifiable communicable diseases, we retrieved all case records from 1997 to 2003 on typhoid and paratyphoid fevers. The data set was compared with data on travel patterns obtained from a comprehensive travel database with information from interviews with more than 16,000 Swedish residents with recent overnight travel outside Sweden. RESULTS The overall risk of being notified with enteric fever after travel was 0.42 in 100,000 travelers. The highest risk for typhoid fever was seen in travelers from India and neighboring countries (41.7 in 100,000), the Middle East (5.91 in 100,000), and Central Africa (3.33 in 100,000), whereas the risk was comparatively low in East Asia (0.24 in 100,000). Almost the same risk areas stood out for paratyphoid fever: India and neighbors (37.5 in 100,000), the Middle East (3.64 in 100,000), and East Africa (3.33 in 100,000). The epidemiology of paratyphoid fever was considerably affected by a large outbreak of paratyphoid B in a Turkish tourist resort in 1999. The youngest children were at highest risk for typhoid fever (odds ratio 44.2), whereas youths ages 7 to 18 years were at highest risk for paratyphoid fever (odds ratio 9.7). CONCLUSIONS Detailed risk data for enteric fever after travel could form the basis for travel advice. Vaccination against typhoid fever should always be considered for travelers to the Indian subcontinent, the Middle East, and Africa but should not routinely be given to travelers to the Malay Peninsula.
1-Bit Reconfigurable Unit Cell Based on PIN Diodes for Transmit-Array Applications in $X$ -Band

An electronically reconfigurable unit cell with 1-bit phase quantization (0°/180°) is proposed for X-band linear polarization transmit arrays. It consists of two rectangular patch antennas loaded by U- and O-slots and connected by a metallized via-hole. The transmission phase is controlled using two p-i-n diode switches integrated in the O-slot. An equivalent lumped-element circuit model is implemented and compared successfully to full-wave simulations. The numerical results are validated experimentally using an ad-hoc waveguide simulator. The prototype exhibits low insertion loss (1.8 dB) with the same level for both phase states, a broad 3-dB transmission bandwidth (14.7%), a 1-dB compression point of 13-15 dBm, and a gain of 5 dBi at 9.75 GHz. The performance and simplicity of the proposed unit cell make it attractive to build electronically steerable transmit arrays in X-band.
The impact of relationship marketing on customer value, satisfaction and loyalty: evidence from banking sector in Indonesia

Indonesia's business community and banks of Indonesia have been contributing significantly to the development of the nation's emerging economy. This paper analyses the impact of relationship marketing on customer value, customer satisfaction, and loyalty in Indonesia's banking sector. Partial least square (PLS) tests conducted on data collected through a survey of 160 customers of banks in Surabaya and Malang have revealed that although relationship marketing does not influence customer satisfaction and loyalty significantly, it does do so with respect to customer value. Furthermore, there exist positively significant relationships between customer value and customer satisfaction and loyalty.