Miracle-dz/UniFAR-FTUs huggingface dataset:
The Cytogenetics and Cell Metabolism of Circulating Reed‐Sternberg Cells

THE morphology of the Reed-Sternberg cell in Hodgkin's disease is well documented. However, knowledge of its metabolism, cytochemistry and cytogenetics is relatively scanty; moreover the origin of the Reed-Sternberg cell remains steeped in controversy (Hoster and Dratman, 1948). The investigation of this cell is usually hampered by the fact that a uniform cell population is not available and a mixed cell population from cultured lymph nodes is often used (Petrakis, Bostick and Siegel, 1959; Ricci, Punturieri, Bosi, Castoldi, 1962; Spriggs and Boddington, 1962). Recently we have had the opportunity to study the cytochemistry, cytogenetics and nucleic acid synthetic rates of a relatively homogeneous population of Reed-Stemberg cells cultured in vituo. The cells were obtained from the peripheral blood of a patient with terminal Hodgkin's disease who manifested Reed-Stemberg cell leukaemia (Ludman and Speer, 1957; Varadi, 1960). It is the purpose of this paper to report the results of these studies and on this basis suggest that the Reed-Sternberg cell is derived @om the lymphocyte.
Effect of Managerial Overconfidence and Compensation on Share Repurchase: Empirical Evidence from Taiwanese Firms

This study analyses the effect of managerial overconfidence and compensation on the behaviour of Taiwanese CEOs who execute share repurchase. A panel data of 715 companies listed in Taiwan Stock Exchange Corporation and over-the-counter from 2008 to 2012 are used for the analysis. Results show that the managers who receive short-term performance bonuses and equity incentives tend to repurchase shares, and these bonuses and incentives are increased when the managers overly estimate the prospects of the company. Overconfident managers are also inclined to use additional capital in buying back shares, especially when they are under a profit-sharing scheme and have additional stock option incentives. The research findings are robust and provide strong policy implications, which advise the board of directors to improve their checks and balances, minimise costly managerial decisions, determine the motives of CEOs in implementing share buybacks, and lessen the information asymmetry inside and outside their business organisations. This study also suggests that future research should look into the tendency of Taiwanese managers to select types of financing (i.e., debt, equity, or a mix) or establish business empires through mergers and acquisitions. Other than the private sector, the case of government-owned and -controlled corporations should also be investigated.
Original or counterfeit luxury fashion brands? The effect of social media on purchase intention

Abstract Italy is the country most affected by the counterfeit phenomenon in Europe. In the field of luxury fashion brands, the relationship between social media marketing (SMM) and consumers’ intention to purchase counterfeit products is still little analyzed. The aim of this pioneering work is to investigate the net impact of SMM communication, user-generated content (UGC), and firm-created content (FCC), on overall brand equity (OBE) and on intention to buy original and counterfeit luxury fashion brands. Findings based on 198 Italian undergraduate students indicate a positive effect of UGC on both OBE and purchase intention of counterfeit products, while purchase intention of original luxury fashion brands is positively affected by OBE and FCC. The last relationship is confirmed when UGC register a low appreciation by users. This study is significant for both academics and practitioners, extending the scope of antecedents influencing the purchase intention of both original and counterfeit luxury fashion products. Findings reveal the fundamental role of UGC as a tool that firms have to manage and monitor due to their moderating effect in the relationship between FCC and intention to buy original luxury fashion brands. This study contributes to providing implications for developing social media brand communications strategies.
99mTc‐MIP‐1404‐SPECT/CT for the detection of PSMA‐positive lesions in 225 patients with biochemical recurrence of prostate cancer

99mTc‐MIP‐1404 (Progenics Pharmaceuticals, Inc., New York, NY) is a novel, SPECT‐compatible 99mTc‐labeled PSMA inhibitor for the detection of prostate cancer. We present results of its clinical use in a cohort of 225 men with histologically confirmed prostate cancer referred for workup of biochemical relapse.
The Moderating Effect of Managerial Ownership and Institutional Ownership on the Relationship between Control Right and Earnings Management

The objective of this paper is to examine how control right affect earnings management in pyramid company ownership. In this study, we proposed that the effect of control right on earnings management is moderated by managerial ownership and institutional ownership. A model was developed and tested using a sample of 108 pyramidal structure companies from 2007 to 2011, listed on Indonesian Stock exchange. Data collected analysis using least square regression. The result showed that there is a significant association between control right and earnings management, and also managerial ownership moderates the association between control right and earnings management. However, the role of institutional ownership as a moderating variable cannot be supported. Overall findings are expected to serve as the basis for more effective corporate performance or effective way to find what factor that affect earnings management practice. Especially managerial ownership is effective to control earnings management practice. Aus. Aca. Acc & Fin. Rev Vol 1(1), July 2015, P 69-85
Correlates of Incident Cognitive Impairment in the REasons for Geographic and Racial Differences in Stroke (REGARDS) Study

Objective: To identify approximately 500 cases of incident cognitive impairment (ICI) in a large, national sample adapting an existing cognitive test-based case definition and to examine relationships of vascular risk factors with ICI. Method: Participants were from the REGARDS study, a national sample of 30,239 African-American and White Americans. Participants included in this analysis had normal cognitive screening and no history of stroke at baseline, and at least one follow-up cognitive assessment with a three-test battery (TTB). Regression-based norms were applied to TTB scores to identify cases of ICI. Logistic regression was used to model associations with baseline vascular risk factors. Results: We identified 495 participants with ICI of 17,630 eligible participants. In multivariable modeling, income (OR 1.83 CI 1.27,2.62), stroke belt residence (OR 1.45 CI 1.18,1.78), history of transient ischemic attack (OR 1.90 CI 1.29,2.81), coronary artery disease(OR 1.32 CI 1.02,1.70), diabetes (OR 1.48 CI 1.17,1.87), obesity (OR 1.40 CI 1.05,1.86), and incident stroke (OR 2.73 CI 1.52,4.90) were associated with ICI. Conclusions: We adapted a previously validated cognitive test-based case definition to identify cases of ICI. Many previously identified risk factors were associated with ICI, supporting the criterion-related validity of our definition.
The presence of family members during cardiopulmonary resuscitation: European Federation of Critical Care Nursing Associations, European Society of Paediatric and Neonatal Intensive Care and European Society of Cardiology Council on Cardiovascular Nursing and Allied Professions joint position statem

This paper presents the European federation of Critical Care Nursing associations, the European Society of Paediatric and Neonatal Intensive Care, and the European Society of Cardiology Council on Cardiovascular Nursing and Allied Professions Joint Position Statement on The Presence of Family Members During Cardiopulmonary Resuscitation. © 2007 Copyright of this position statement is jointly owned by the European Federation of Critical Care Nursing associations, the European Society of Paediatric and Neonatal Intensive Care, the Council on Cardiovascular Nursing and Applied Professions, and Connect Healthcare Publishing Ltd. Published by Elsevier B.V. All rights reserved.
Carbon nanotube field effect transistors for logic applications

Presents new experimental data for single-wall carbon nanotube based field-effect transistors (CNFETs). New metal-nanotube contacts are shown to improve the performance of the CNFETs over previously reported values. Assuming conventional scaling, the improved device performance suggests that CNFETs may be competitive with Si-FETs and require no new circuit paradigm and architecture.
PENGARUH PROFITABILITAS, GROWTH, KEBIJAKAN HUTANG DAN KEPEMILIKAN INSTITUSIONAL TERHADAP KEBIJAKAN DIVIDEN

ABSTRACT The purpose of this research is to examine the influence of profitability variable which is measured by return on assets (ROA), growth is measured by using total assets (GRT), debt policy is measured by debt to equity ratio (DER), institutional ownership is measured by (INST), and dividend policy is measured by dividend payout ratio (DPR). The population is all consumer goods industrial sector manufacturing companies which are listed in Indonesia Stock Exchange. The data has been obtained from www.idx. co.id and STIESIA Indonesia Stock Exchange Corner. 13 sample companies have been selected as sample by using purposive sampling technique with the criteria industrial manufacturing companies which are listed in Indonesia Stock Exchange in 2012-2015 periods. The predictive ability of profitability, growth, debt policy, institutional ownership to the DPR is 54.9% as it is described by the magnitude of adjusted R-square is 0.549 or 54.9%, whereas the remaining 45.1% is influenced by other factors which are not included in the research model. The result of the research shows that profitability (ROA) and debt policy (DER) does not give any influence to the DPR. Growth, in this research, gives negative influence to the DPR and institutional ownership gives positive influence to the DPR. Keywords: Profitability, growth, debt policy, institutional ownership, dividend policy
Pathological narcissism and depressive symptoms in psychiatric outpatients: mediating role of dysfunctional attitudes.

OBJECTIVE The aim of this study was to examine the relationships between pathological narcissism (narcissistic grandiosity and narcissistic vulnerability), dysfunctional attitudes (perfectionism and dependency on other people), and depressive symptoms in psychiatric outpatients. METHOD A sample of 234 adult psychiatric outpatients (57.3% male; mean age 44.39 years) completed the Pathological Narcissism Inventory, the Dysfunctional Attitudes Scale-Form A, and the Depression, Anxiety, Stress Scales-21. RESULTS Narcissistic vulnerability exhibited unique positive correlations with depressive symptoms, whereas narcissistic grandiosity showed substantially weaker correlations with depressive symptoms. Perfectionism partially mediated the relationship between narcissistic vulnerability and depressive symptoms. The mediating role of dependency was not confirmed. CONCLUSIONS Among adult psychiatric outpatients, narcissistic vulnerability is more strongly related to depressive symptoms than narcissistic grandiosity, and dysfunctional perfectionism represents one of the underlying mechanisms of this relationship. The implications of these findings are discussed in relation to the Diagnostic and Statistical Manual of Mental Disorders diagnostic criteria and the treatment of pathological narcissism.
Vascular Endothelial Growth Factor Induces Expression of Connective Tissue Growth Factor via KDR, Flt1, and Phosphatidylinositol 3-Kinase-Akt-dependent Pathways in Retinal Vascular Cells*

Fibroblastic proliferation accompanies many angiogenesis-related retinal and systemic diseases. Since connective tissue growth factor (CTGF) is a potent mitogen for fibrosis, extracellular matrix production, and angiogenesis, we have studied the effects and mechanism by which vascular endothelial growth factor (VEGF) regulates CTGF gene expression in retinal capillary cells. In our study, VEGF increased CTGF mRNA levels in a time- and concentration-dependent manner in bovine retinal endothelial cells and pericytes, without the need of new protein synthesis and without altering mRNA stability. VEGF activated the tyrosine receptor phosphorylation of KDR and Flt1 and increased the binding of phosphatidylinositol 3-kinase (PI3-kinase) p85 subunit to KDR and Flt1, both of which could mediate CTGF gene induction. VEGF-induced CTGF expression was mediated primarily by PI3-kinase activation, whereas PKC and ERK pathways made only minimal contributions. Furthermore, overexpression of constitutive active Akt was sufficient to induce CTGF gene expression, and inhibition of Akt activation by overexpressing dominant negative mutant of Akt abolished the VEGF-induced CTGF expression. These data suggest that VEGF can increase CTGF gene expression in bovine retinal capillary cells via KDR or Flt receptors and the activation of PI3-kinase-Akt pathway independently of PKC or Ras-ERK pathway, possibly inducing the fibrosis observed in retinal neovascular diseases.
Cooperative load balancing on human moving trajectory diversity in cellular networks

Human dynamics are investigated for deployment of picocell in cellular network in this paper. Human dynamics may lead to variation of channel condition, e.g., moving fast or slow, driving in a mega city or in a countryside may change channel conditions. The data delivery throughput depends on user distribution, commuting trajectory, and Internet access regularity. Effectiveness of frequency reuse assisted from picocell deployment is affected by human dynamics. By applying human dynamics to a network management strategy, the effectiveness of frequency reuse can be improved in practice. Pricing strategy and resource management can be reconsidered according to users' loyalty with respect to a service provider. Novel pricing strategies based on user's request-to-receive ratio are also proposed. Computer simulations verify the improvements obtained using the proposed methods.
Applying Natural Language Processing Capabilities in Computerized Textual Analysis to Measure Organizational Culture

We build on and extend methodological developments in computerized textual analysis and apply it for developing and validating a measure for the widely used concept of organizational culture. Although the organizational culture concept is widely used in a variety of domains of management scholarship, its measurement is primarily based on survey questionnaires. In this study, we extend computerized textual analysis by introducing the capabilities of natural language processing (NLP). NLP capabilities are artificial intelligence techniques for textual analysis that make it possible to conduct textual analysis at the multiple word level. We follow recommendations for establishing construct validity and demonstrate that the measure of organizational culture dimensions outlined in the study has content validity, external validity, dimensionality, and predictive validity.
Effects of a Periodized Small-Sided Game Training Intervention on Physical Performance in Elite Professional Soccer

Abstract Owen, AL, Wong, DP, Paul, D, and Dellal, A. Effects of a periodized small-sided game training intervention on physical performance in elite professional soccer. J Strength Cond Res 26(10): 2748–2754, 2012—The present study examined the effects of periodized small-sided game (SSG) training intervention during a 4-week in-season break on the physical performance changes (i.e., speed, aerobic performance, and repeated sprint ability) within elite European soccer players. Fifteen, elite, male, professional players (age: 24.5 ± 3.45 years; height: 181.1 ± 5.78 cm; body mass: 78.7 ± 7.67 kg; V[Combining Dot Above]O2max: 54.88 ± 5.25 ml·kg−1·min−1) from a Scottish Premier League team participated in 7 separate SSG sessions (3 vs. 3 plus goalkeepers) of which games lasted for a 3-minute duration for the selected number of games (ranged from 5 to 11) increasing over the intervention period. To examine the effects of the SSG intervention on physical performance changes, pre- and posttesting sessions took place over a 2-day period (day 1: anthropometry and repeated sprint ability [RSA] assessments; day 2: running economy [RE] and blood lactate assessments). Results show that the 4-week SSG training intervention induced significant improvement in RSA as indicated by faster 10-m sprint time (p < 0.05, small effect), total sprint time (p < 0.05, medium effect), and smaller percentage decrement score (p < 0.05, medium effect). Furthermore, the SSGs also led to an improvement in RE as indicated through significantly reduced V[Combining Dot Above]O2 and heart rate at running speed 9, 11, and 14 km·h−1 (all p's < 0.05, large effects). In conclusion, the present study demonstrates that implementing a periodized SSG training intervention during the 4-week in-season break is capable of improving elite-level soccer players' physical fitness characteristics. Being able to develop physical characteristics in conjunction to technical and tactical elements of the game, within a relatively short period, makes SSGs an appealing proposition for fitness coaches, players, and technical coaches alike.
Megacystis, megacolon, and malrotation: A new syndromic association?

Chronic intestinal pseudo‐obstruction (CIPO) can occur as a consequence of neuropathies including diffuse Intestinal Neuronal Dysplasia (IND), a relatively rare enteric nervous system (ENS) abnormality. Although various authors reported of diffuse IND associated either with intestinal malrotation or megacystis, the co‐existence of these three entities in the same patient has never been described before. The aim of this paper is to report for the first time in literature a series of patient with such association, focusing on one who carries a de novo duplication of chromosome 12, suggesting a new syndromic association (megacolon, megacystis, malrotation). © 2011 Wiley‐Liss, Inc.
Genetic and Pathogenetic Aspects of Noonan Syndrome and Related Disorders

Noonan syndrome (NS) and the clinically overlapping disorders cardio-facio-cutaneous syndrome, LEOPARD syndrome, Costello syndrome and Neurofibromatosis-Noonan syndrome share the clinical features of short stature, the same spectrum of congenital heart defects, and a similar pattern of craniofacial anomalies. It is now known that all these disorders are caused by mutations in components of the RAS-MAPK signaling pathway. This pathway was previously known for its involvement in tumorigenesis. This article reviews the current knowledge on underlying genetic alterations and possible pathogenetic mechanisms responsible for NS and related disorders. It discusses the relationship between a group of developmental disorders and oncogenes. Potential future treatment prospects are based on the possibility of inhibiting RAS-MAPK signaling by pharmaceuticals.
The Role of Leadership Styles In Building and Sustaining Corporate Reputation – Empirical Investigation On Islamic Banks In Jordan

Leadership is the art and science of affecting the others; leaders in different organizational settings play a crucial role in achieving organizational goals, by establishing and offering motivational atmosphere for their employees. However, the main objective of this research is to build a theoretical model of leadership styles and corporate reputation in order to empirically within the context of Islamic banks operating in Jordan. The researcher used a quantitative methodological approach through a structured questionnaire to gather data from the research respondents. The sample size consisted of 640 employees from low-mid managerial levels. The researcher used descriptive statistics, multiple regression models and weighted least square analyses to examine the relationship between the research variables. Accordingly, the results revealed that both (transactional and transformational) leadership styles have a positive influence on corporate reputation. Meanwhile, transformational leadership style showed a positive and significant influence on corporate reputation. Also, privacy has a non-significant effect on mobile marketing acceptance but its effect is positive. Further, employee empowerment was found as mediator variable. Research conclusions, Limitations and recommendations for future work were also discussed.
Agency costs and moral hazard under the new banks' capital regulation : diagnosis, modelling and solutions

This thesis investigates the agency costs and moral hazard associated with the new capital regulation for banks in the event of balance-sheet losses. The recent introduction of "Bail-in" provisions, under which unsecured creditors must contribute to banks’ rescue through recapitalisation, and the regulatory stipulation of higher equity requirements, will have profound effects on the traditional agency relationships between shareholders and bondholders of banks. These Bail-in provisions imply, "Deviations from the Absolute Priority Rule" (DAPR). This dissertation undertakes quantitative and qualitative analyses of the new Bail-In structures, focusing on their microeconomic consequences that lead to perverse incentives of the equityholders and subsequently propose practical solutions to the identified problems. The first main result reveals that Bail-in could actually aggravate the agency costs by intensifying the "wealth transfer" from bondholders to equityholders. The second main result is to demonstrate that enforcing higher monitoring costs to the bondholders reduces equityholders’ incentive for moral hazard via higher cost of capital. The use of financial and non-financial covenants within the "Bail-In-Able Debt" indenture has been proposed as practical solutions to facilitate bondholders’ monitoring efforts. However, close to the Point of Non-Viability covenants are no longer effective as the risk of DAPR looms, and the equityholders are tempted to attempt "gamble-for-resurrection". To attenuate this distortion of shareholder incentives, Bail-in provision must impose some cost on shareholders. They could be made to face significant dilution, through a fair debt-to-equity swap with bondholders at market prices, or face full dilution via private expropriation by a new shareholder base that we term "Contingent Equity Base". This is the third main result. Overall, this dissertation makes a significant step forward into the understanding of the microeconomic consequences of the new bank’s capital regulation in general and the Contingent Convertibles in particular whilst offering practical solutions to the problems.