Miracle-dz/UniFAR-FTUs huggingface dataset:
Burn injuries and adolescents in Israel

Burn injury is a public health concern often associated with individual pain, emotional stress, prolonged hospitalizations, permanent disfigurement and family stress. In this paper we studied the avaliable data on burn injury among adolescents in Israel through a Medline search and found three relevant studies with data on this population. The incidence rate of burn injury was 0.46 per 1,000 children aged 5-14 years for Jews and 0.91 for Bedouin. Most of the burn injury in this age group was caused by hot liquids, followed by fire and chemical burns for both Jews and Bedouin, but electical burns occurred more often in Bedouins. Mortality was very low for the adolescent group. Prevention programs in schools since the 1980s have been found effective, but the public health focus should now be geared towards groups at risk.
Differential effects of hypoxia on the intracellular Ca2+ concentration of myocytes isolated from different regions of the rat pulmonary arterial tree

Hypoxic pulmonary vasoconstriction (HPV) may be mediated, in part, by an oxygen‐sensing mechanism intrinsic to pulmonary arterial smooth muscle. It has been proposed that hypoxia inhibits a K+ conductance, which promotes membrane depolarization, subsequent activation of L‐type Ca2+ channels and ultimately constriction. We have monitored hypoxia‐induced changes in the intracellular Ca2+ concentration ([Ca2+]i) of single myocytes isolated from the rat pulmonary arterial tree using microspectrofluorimetry and ratiometric measurement of indo‐1 fluorescence. The basal level of [Ca2+]i was in the range 35–80 nM and cells were quiescent at rest exhibiting no spontaneous oscillations in [Ca2+]i. When the extracellular K+ concentration ([K+]o) was raised to 20 mM, the [Ca2+]i increased from approximately 60 to approximately 100 nM. This increase was abolished by nifedipine, demonstrating the presence, and need for activation, of functional voltage‐gated L‐type Ca2+ channels. Hypoxia (PO2 < or = 30 mmHg; throughout) had little effect on the resting [Ca2+]i in myocytes isolated from either the main intrapulmonary artery, or its primary, secondary or tertiary branches. However, upon raising the [Ca2+]i by increasing [K+]o to 20 mM, hypoxia was found to lower [Ca2+]i from approximately 110 to approximately 70 nM, in cells isolated from the main conduit and primary branches of the intrapulmonary artery. In marked contrast, when [Ca2+]i was raised, by increasing [K+]o to 20 mM, in myocytes isolated from secondary and tertiary branches of the intrapulmonary artery, hypoxia induced a further reversible increase in the [Ca2+]i from approximately 160 to approximately 240 nM. Neither hypoxia alone nor in combination with 20 mM K(+)o induced any increase in the [Ca2+]i in the presence of nifedipine. We conclude that hypoxia may modulate [Ca2+]i in rat pulmonary artery myocytes only following its elevation by a depolarizing stimulus.
Effectiveness of Three Best Management Practices for Highway-Runoff Quality along the Southeast Expressway, Boston, Massachusetts

1 Appendix 1. Summary Statistics and Analytical Results from the Evaluations of Effectiveness for Three Best Management Practices for Highway-Runoff Quality along the Southeast Expressway, Boston, Massachusetts CD-ROM Introduction 3 Description of Study Area and Highway-Drainage Systems 4 Acknowledgments 6 Methods for Continuous Monitoring of Highway Drainage 9 Design of Highway-Drainage Monitoring Stations 11 Measurement of Discharge 11 Measurements of Turbidity, Specific Conductance, and Water Temperature 12 Collection and Analysis of Samples 14 Automatic Sample Collection 14 Suspended Sediment 14 Water Chemistry 16 Bacteria 17 Miscellaneous Debris Samples 17 Measurement of Volume and Mass of Bottom Material in the Oil-Grit Separators and the Catch Basin 17 Collection of Bottom-Material Samples from the Oil-Grit Separators 19 Sediment Samples from Mechanical Street Sweepers 20 Quality Assurance/Quality Control 21 Quality-Control Samples 21 Quality-Control Data 23 Analysis of Data 29 Suspended-Sediment Loads 30 Efficiencies of Structural BMPs 32 Annual Suspended-Sediment Loads 32 Predictors for Unsampled Suspended-Sediment Loads 33 Assessment of Best Management Practices 37 Temporal Variability of Retained Bottom Material 37 Particle-Size Distribution and
Magnetic Resonance-Guided Focused Ultrasound Myomectomy

We performed a systematic review about studies reporting data of myomectomy performed by magnetic resonance-guided focused ultrasound (MRgFUS) technique in order to define its safety, feasibility, indications, complications, and impact on uterine fibroid symptom and health-related quality of life (UFS-QOL) and fertility. Outcomes were considered according to fibroids shrinkage, nonperfused volume (NPV), NPV ratio, and uterine fibroid symptoms assessed with UFS-QOL questionnaire (baseline 3, 4, 6, and 12 months). We analyzed 38 eligible studies reporting outcomes about 2500 patients (mean age 43.67 years). The MRgFUS results a safe, efficient, and cost-effective minimal invasive technique for treatment of uterine fibroids. Increasing experience, device improvements, and availability for a larger number of patients are enhancing the outcomes, while the obstetrical ones should be more extensively explored. The MRgFUS could be considered as a minimal invasive alternative to traditional surgical or radiological procedures for the treatment of symptomatic uterine myomas improving both QOL and subsequent fertility.
You have been poked: Exploring the uses and gratifications of Facebook among emerging adults

The social networking site Facebook has become an inescapable phenomenon for college students, but little systematic research has studied why these students use Facebook. I conducted an online survey among Facebook users at the University of North Carolina at Chapel Hill (N = 1,049) to examine why they use Facebook and how it fulfills their needs. The most prevalent use of Facebook was as a social activity – students reported using Facebook with friends to view and discuss other people’s profiles. Essentially, Facebook appears to operate primarily as a tool for the facilitation of gossip.
The Effects of Deposition Rate and Annealing on CoFeB/MgO/CoFeB Perpendicular Magnetic Tunnel Junctions

In this study, we report the effects of deposition rate and composition of CoFeB on the magnetic properties of CoFeB/MgO/CoFeB structures. We found that the asymmetry exists not only in different deposition stack sequences (bottom structure Ta/CoFeB/MgO and top structure MgO/CoFeB/Ta), but also in different compositions of CoFeB. Co<sub>40</sub>Fe<sub>40</sub>B<sub>20</sub> is more suitable for the bottom structure, while Co<sub>20</sub>Fe<sub>60</sub>B<sub>20</sub> has better perpendicular magnetic anisotropy for the top structure. Based on the results The full pMTJ stacks of structure Ta 5/Co<sub>40</sub>Fe<sub>40</sub>B 1.3/MgO 1/Co<sub>20</sub>Fe<sub>60</sub>B<sub>20</sub> 2.2/Top layer (nm unit) were fabricated with different deposition rates and annealing temperatures. We found that low deposition rate (0.03 nm/s) can prevent overlapping magnetization reversal of both free and fixed layer. The antiferromagnetic coupling between the free and fixed layer was found to increase with annealing temperature which can be identified as the consequence of orange-peel coupling.
Ten-year longitudinal change in aortic stiffness assessed by cardiac MRI in the second half of the human lifespan: the multi-ethnic study of atherosclerosis.

AIMS Longitudinal determinants of aortic stiffness (AS) measured by magnetic resonance imaging (MRI) have not been assessed in a large community-based population. Our aim was to examine the determinants of change in thoracic AS over 10 years of follow-up in a multi-ethnic population of individuals 45 years of age and older measured by MRI. METHODS AND RESULTS We studied 1160 participants (mean age = 60 ± 9 years at baseline, 45% male) with aortic MRI at both the MESA Year 0 and Year 10 examinations. Ascending and descending aorta distensibility (AAD/DAD) and aortic arch pulse-wave velocity (PWV) were measured using MRI. Determinants of the change in AS parameters over 10 years were assessed using linear regression adjusted for baseline values, demographic variables, baseline risk factors and change in risk factors, and chronic risk exposure. AAD and DAD decreased slightly (5% decrease in median for AAD: 1.33-1.26 mmHg(-1) · 10(-3), P = 0.008; 5% decrease in median for DAD: 1.73-1.64 mmHg(-1) · 10(-3), P < 0.001), and PWV increased over 10 years (18% increase in median: 6.8-8.0 m/s P < 0.001). Baseline age was related to a reduction in AAD and DAD and an increase in PWV throughout the follow-up period. Baseline and change in mean blood pressure and continued smoking were associated with a reduction in AAD and an increase in PWV. Furthermore, baseline heart rate was also related to a reduction in AAD and DAD. Blood pressure normalization was related to less aortic stiffening throughout the follow-up period. CONCLUSIONS In our longitudinal, community-based cohort study of adult individuals aged 45 years or greater, greater mean blood pressure and a history of smoking history were associated with increased aortic stiffening over 10 years as assessed by MRI.
SRG Inscription in Supramolecular Liquid Crystalline Polymer Film: Replacement of Mesogens

The photoinduced surface relief formation via mass transfer upon irradiation with patterned light has long been a subject of extensive investigation. In azobenzene-containing liquid crystalline materials, UV light irradiation that generates the cis isomer leads to the liquid crystal to isotropic photochemical transition. Due to this phase change, efficiency of the mass transfer to generate a surface relief grating (SRG) becomes markedly greater. We have previously indicated that azobenzene-colored SRG-inscribed film can be bleached by removing a hydrogen-bonded azobenzene mesogen. However, this process largely reduces the height feature of the SRG corrugation. Herein, we propose an extended procedure where a colorless mesogen is filled successively after the removal of the azobenzene side chain. The process involves four stages: (i) SRG inscription in a hydrogen-bonded supramolecular azobenzene material; (ii) crosslinking (insolubilization) of the SRG film; (iii) removal of azobenzene mesogen by rinsing with a solvent, and (iv) stuffing the hollow film with a different mesogen. Although the final stuffing stage was insufficient at the present stage, this work demonstrates the possibility and validity of the strategy of mesogen replacement.
Potential genetic markers of sporadic Alzheimer's dementia

Polymorphisms within the genes encoding apolipoprotein E (ApoE), apolipoprotein CI (ApoCI), α1-antichymotrypsin (ACT), the low-density lipoprotein (LDL) receptor and lipoprotein lipase were investigated in patients suffering from Alzheimer's dementia and non-demented psychiatric patients as control subjects. The ApoE allele 4, well known as a risk factor in Alzheimer's disease, and the ApoCI allele A2, which is closely linked to the ApoE allele 4, were found elevated in the index group. Concerning the polymorphism within exon 8 of the LDL receptor (alanin/threonin), there was also a predominance of the allele carrying threonin in the index group, which barely missed significance. Distribution of the polymorphisms of ACT and lipoprotein lipase were similar in both groups investigated. We conclude that, apart from the ApoE allele 4, other genetically regulated factors like ApoCI and the LDL receptor modulate the individual risk for Alzheimer's disease.
ANAEROBIC GRANULATION WITH METHANOL-CULTURED SEED SLUDGE

A new biotechnology on sludge granulation in upflow anaerobic sludge blanket (UASB) system was developed in this study. Methanol-cultured sludge for UASB inoculation demonstrated a beneficial effect on the granulation process. This new biotechnology accelerated the formation of embryonic granules in a laboratory-scale UASB reactor, and the granulation process reached its post-maturation stage in about 15–20 days ahead of the control reactor. There were no significant negative effects on COD removal and gas production due to this methanogen-enriched seed sludge. Methanol-cultured seed sludge for UASB inoculation could be an effective method to reduce the time required for UASB system start-up.
Fermentation extract effects on the morphology and metabolism of the rumen fungus Neocallimastix frontalis EB188

The effects of Aspergillus oryzae fermentation extract, AmafermTM, on the rumen fungus Neocallimastix frontalis EB188 were studied. The secretion of cellulase was increased by 67% and rhyzoid development was increased 3·8‐fold in the presence of extract. Strength of fungal response increased in a dose‐dependent manner and demonstrated a positive correlation between cell surface area and enzyme secretion. Above certain concentrations of extract, however, the development of the fungus and enzyme secretions remained at control values or slightly diminished. Supernatant fluid appearance of the intracellular enzyme, malate dehydrogenase, paralleled the secretion of cellulase both in the presence and absence of extract. Ether solubilization of extract demonstrated that the active component(s) possessed a moderately polar value between 2·7 and 2·8. Thin layer chromatography separated extract into inert, inhibitory and intensely stimulating fractions. These results support the idea that by accelerating fungal growth and metabolism, AmafermTM increases the rate (or extent) of fibre degradation caused by rumen fungi and that this, in turn, may contribute to enhanced animal performance.
Studies of the reticuloendothelial system (RES). I. Measurement of the phagocytic capacity of the RES in man and dog.

When human serum albumin is aggregated under standardized conditions, a polymer is obtained that can be successfully used to study the phagocytic capacity of the reticuloendothelial system (RES) in man. In addition to careful control of pH, temperature, amount of agitation, and concentration of the albumin solution, it is necessary to monitor the changes in optical density, to insure adequacy of the prepared material by bioassay in man, or dog, or both, and to conduct simultameous control studies in normal subjects during the study of patients. Large doses of aggregated albumin can be safety administered over prolonged periods to human subjects without evidence of hypersensitivity or excessive radiation. The phagocytic capacity of the RES in both man and dog was determined experimentally with the analytical method of Michaelis and Menten. In man, this maximal rate of phagocytosis of aggregated albumin was 1.07 mg per minute per kg of body weight. (auth)
Dancing in Pain: Pain Appraisal and Coping in Dancers

This study investigated the relationships between the type of pain experienced (performance pain andinjury pain), the cognitive appraisal of pain and pain coping styles in dancers. Fifty-one professional ballet and contemporary dancers (17 males and 34 females), with the mean age of 25.9 years, completed a general pain questionnaire, the Pain Appraisal Inventory, the Survey of Pain Attitudes Control Subscale, and the Sports Inventory for Pain. Multivariate analyses of variance indicated that both the cognitive appraisal of the pain and pain coping styles did not differ according to the type of pain experienced or the pain severity. However, it was found that dancers with performance pain of either low or high severity were more likely to dance in pain than dancers experiencing injury pain. Multiple regression analyses indicated that the appraisal of pain as threatening was predictive of the use of avoidance and catastrophizing pain coping styles. Overall, results indicated that dancers may not differentiate between performance pain and injury pain, or modify their appraisal and coping strategies according to the characteristics of the pain experienced. The study highlighted an opportunity for increased education for dancers in recognizing the difference between pain considered to be a routine aspect of training and pain which is a signal of serious injury.
Gender Differences in Violence Exposure and Violence Risk among Adolescent Inpatients

Gender-specific rates of violence exposure and violence perpetration among psychiatrically ill adolescents has received little scientific attention. We examined 130 adolescent inpatients and found no difference between male and female subjects with respect to self-reported violence potential or actual violence perpetration. Female inpatients, however, were significantly more often victims of sexual assault, and male inpatients were significantly more often victims of physical assault. For male inpatients, a history of violence perpetration in one area was closely linked with a history of violence victimization in the same area. Alternatively, patterns of victimization and perpetration among female inpatients were less predictable and had crossover to victimization and perpetration experiences in other areas. Correlational analyses revealed that violence risk was associated with a broad range of internalizing and externalizing psychopathology. Significant associations with hopelessness, suicidality, and childhood trauma differentiated the violence risk of male and female inpatients. We propose a hypothesis for understanding these differences and conclude that although psychiatrically ill adolescent male and female patients may commonly fall victim to differing forms of violence, both genders are at equal risk for actual violence perpetration.
Effects of concomitant spinal cord injury and brain injury on medical and functional outcomes and community participation.

BACKGROUND There are limited data on the interactions between concomitant spinal cord injury (SCI) and traumatic brain injury (TBI) in terms of medical, psychological, functional, and community outcomes. OBJECTIVE To investigate the hypothesis that in addition to SCI-associated sensory-motor impairments, people with dual diagnosis would experience additional TBI-associated cognitive impairments that would have a negative impact on community reintegration. METHODS Cross-sectional, case-matched study comparing a consecutive sample of participants with dual diagnosis (n = 30) to an SCI group (n = 30) and TBI group (n = 30). Participants who were on average 3.6 years postrehabilitation discharge were interviewed using a battery of standardized outcome measures. RESULTS Length of rehabilitation stay was significantly longer in SCI and dual diagnosis participants. Fatigue, pain, sexual dysfunction, depression, and sleep disturbances were frequently reported by all groups. Similar levels of anxiety and depression were reported by participants in all groups, however TBI participants reported higher stress levels. All groups achieved mean FIM scores > 100. The dual diagnosis and SCI groups received more daily care and support than TBI participants. Similar levels of community reintegration were achieved by all groups with a high level of productive engagement in work, study, or volunteer activities. CONCLUSIONS The findings of this study do not support the hypotheses. Postrehabilitation functioning was better than anticipated in adults with dual diagnosis. The contribution of rehabilitation factors, such as longer admission time to develop compensatory techniques and strategies for adaptation in the community, may have contributed to these positive findings.
Raman Spectroscopy of Xylitol Uptake and Metabolism in Gram-Positive and Gram-Negative Bacteria

ABSTRACT Visible-wavelength Raman spectroscopy was used to investigate the uptake and metabolism of the five-carbon sugar alcohol xylitol by Gram-positive viridans group streptococcus and the two extensively used strains of Gram-negative Escherichia coli, E. coli C and E. coli K-12. E. coli C, but not E. coli K-12, contains a complete xylitol operon, and the viridans group streptococcus contains an incomplete xylitol operon used to metabolize the xylitol. Raman spectra from xylitol-exposed viridans group streptococcus exhibited significant changes that persisted even in progeny grown from the xylitol-exposed mother cells in a xylitol-free medium for 24 h. This behavior was not observed in the E. coli K-12. In both viridans group streptococcus and the E. coli C derivative HF4714, the metabolic intermediates are stably formed to create an anomaly in bacterial normal survival. The uptake of xylitol by Gram-positive and Gram-negative pathogens occurs even in the presence of other high-calorie sugars, and its stable integration within the bacterial cell wall may discontinue bacterial multiplication. This could be a contributing factor for the known efficacy of xylitol when taken as a prophylactic measure to prevent or reduce occurrences of persistent infection. Specifically, these bacteria are causative agents for several important diseases of children such as pneumonia, otitis media, meningitis, and dental caries. If properly explored, such an inexpensive and harmless sugar-alcohol, alone or used in conjunction with fluoride, would pave the way to an alternative preventive therapy for these childhood diseases when the causative pathogens have become resistant to modern medicines such as antibiotics and vaccine immunotherapy.
Multisensory emotions: perception, combination and underlying neural processes

Abstract In our everyday lives, we perceive emotional information via multiple sensory channels. This is particularly evident for emotional faces and voices in a social context. Over the past years, a multitude of studies have addressed the question of how affective cues conveyed by auditory and visual channels are integrated. Behavioral studies show that hearing and seeing emotional expressions can support and influence each other, a notion which is supported by investigations on the underlying neurobiology. Numerous electrophysiological and neuroimaging studies have identified brain regions subserving the integration of multimodal emotions and have provided new insights into the neural processing steps underlying the synergistic confluence of affective information from voice and face. In this paper we provide a comprehensive review covering current behavioral, electrophysiological and functional neuroimaging findings on the combination of emotions from the auditory and visual domains. Behavioral advantages arising from multimodal redundancy are paralleled by specific integration patterns on the neural level, from encoding in early sensory cortices to late cognitive evaluation in higher association areas. In summary, these findings indicate that bimodal emotions interact at multiple stages of the audiovisual integration process.