Miracle-dz/UniFAR-FTUs huggingface dataset:
Activismo, co-creación e igualdad de género: la comunicación digital en la huelga feminista del 8M.

Presentamos un análisis de las estrategias de comunicación digital empleadas durante la huelga feminista del 8 de marzo de 2018. Coincidiendo con Día Internacional de la Mujer, se convocaron en 170 países huelgas feministas laborales, estudiantiles, de consumo y de cuidados. La jornada estuvo protagonizada por importantes movilizaciones en las principales ciudades. La repercusión mediática, política y social del evento sobrepasó considerablemente las expectativas que parecían haberse depositado en tal evento. Analizamos la actividad de la web elaborada ex-profeso para el evento (http://www.hacialahuelgafeminista.org) y la co-creación de contenidos comunicativos que se articulan a través de la comisión de comunicación, encargada de la relación con medios de comunicación (prensa/TV); el diseño gráfico unitario y la comunicación online tanto interna como externa: correo electrónico, redes sociales y web. Más allá del evento reivindicativo del 8 de marzo, estas plataformas siguen operativas meses después aunque con un nivel de actividad menor y vehiculando informaciones referidas a movilizaciones y acciones reivindicativas que siguen realizándose en el territorio nacional. Reflexionamos sobre los nuevos modelos de artivismo (activismo artístico) a través de la participación de ilustradoras y artistas independientes que pusieron su obra al servicio de dicha causa, mediante sus aportaciones en la cuenta de la red social Instagram. Discutimos finalmente la presencia de Internet (redes sociales, blogs, medios digitales, web…) como espacio de ocupación creativa con propuestas que se alejan de lo performativo y abundan en lo icónico y simbólico.
Coaxial feeds for high aperture efficiency and low spillover of paraboloidal reflector antennas

Coaxial feeds produce an approximate sector-shaped pattern, an almost optimum pattern of a feed for high aperture efficiency and low spillover of paraboloid antennas. Such a coaxial feed consists of a central circular waveguide which is surrounded by one or more conductors with circular cross sections. Theoretical and experimental investigations on coaxial feeds excited by H 11 modes have shown that the first ring yields the highest increase in the aperture efficiency of paraboloid antennas illuminated by them. Measurements performed on paraboloid antennas illuminated by a coaxial feed with only one ring yielded aperture efficiencies of 68 to 75 percent for angular apertures of the paraboloidal reflector of 100\deg to 160\deg . Circularly symmetric patterns in conjunction with almost linearly polarized aperture fields can be achieved by multimode coaxial feeds. The values for the aperture efficiency, which are calculated for paraboloid antennas illuminated by multimode coaxial feeds, nearly reach the theoretical optimum. The measured values are 68 to 80 percent. In addition, the multimode feeds produce very little cross polarization.
Feasibility and Safety of Single-Probe Cryoablation with Liquid Nitrogen: An Initial Experience in 24 Various Tumor Lesions

Simple Summary Percutaneous cryoablation was developed to minimally perform multi-organ tumor ablations. The most widely known cryotherapy systems use argon gas (high-pressure) and multiple needles to achieve sufficient ablations. The aim of our retrospective study was to assess the feasibility of a new cryotherapy system using single-probe liquid nitrogen for tumor lesions of various sizes and locations, and to evaluate the safety of cryoablation with this technique. Correlations between ice ball sizes and ablation zone sizes with two needle sizes (10G or 13G) and with the freezing duration were evaluated, as well as the sphericity of the ice ball and ablation zones. We showed that this technique is safe in all organs tested. We showed a correlation between the freezing duration and the ice ball size, but not with the ablation zone, which is useful for planning the procedure and treatment conducted by the oncology team. Abstract Background: Percutaneous cryoablation with liquid nitrogen is a new technique being used in the treatment of some malignant tumors. Our objective was to assess its feasibility in the ablation of tumor lesions of various sizes and locations. Methods: This retrospective, monocentric study included all consecutive patients who underwent percutaneous cryoablation with liquid nitrogen between December 2019 and March 2021. Cryoablation was performed using 10G or 13G cryoprobes. The ablation volume was measured on post-treatment CT or MRI. Results: 22 patients (24 lesions) were included, 16 of whom were men (73%), while median age was 66 years. The lesions were located in the bone (42%), kidney (29%), soft tissue (17%), lung (8%), or liver (4%). It was feasible in all tumor locations and produced median ablation zones 25 mm in width and 35 mm in length, with a 23 min median freezing time. Freezing duration was correlated with the ice volume (p Spearman = 0.02), but not with the ablation volume (p = 0.11). The average difference between the ablation zone and ice ball sizes were −6.4 mm in width and −7.7 mm in length. Both ice and ablation volumes were larger when using the 10G probe as compared to when the 13G was used. No complications were reported. Discussion: We showed that this technique was safe and feasible in all organs tested. The freezing duration was correlated with the ice ball size, but not with the ablation zone.
Big Data-Driven Contextual Processing Methods for Electrical Capacitance Tomography

This paper presents a new approach to analyzing measurement records from industrial processes. The proposed methodology is based on the model of contextual processing and uses big data from experimental process tomography datasets. Electrical capacitance tomography is used for monitoring noninvasive flow and for data acquisition. The measurement data are collected, stored, and processed to identify process regimes and process threats. A specific physical modification was introduced into the pneumatic conveying flow rig in order to study flow behavior under extreme conditions, extending the available knowledge base. A support vector machine was applied for data classification. This study illustrates how contextual processing can facilitate data interpretation and opens the way for the development of methods for detecting pre-emergency flow patterns.
Curating Illustrations of Lewis Carroll’s Alice’s Adventures in Wonderland

viii CHAPTER ONE: INTRODUCTION . 1 Context: Why Wonderland? 3 Purpose . 4 Perspectives and Processes . 5 CHAPTER TWO: A REVIEW OF THE LITERATURE . 9 Foundations for Understanding Wonderland Illustration . 10 Reading Illustrative Interpretations . 14 The Relatedness and Complexity of Text . 16 Linguistic semiotics . 17 Discourse . 17 Literary Frames and Methods of Critique . 18 Narrative Language in Literature. 20 Visual Interpretations . 20 Elements of design . 21 Visual semiotics . 22 Finding Meaning In Illustration. 24 Indeterminacies in words and illustrations . 25 Theories of picturebook reading . 26 Interpreting Multiple Modes . 26 Meaning in Historical Constructions of Literature for Children . 28 Reading Historical Texts . 29 Reading Wonderland . 29 A Brief Synopsis of Wonderland . 31 Wonderland’s Historical Contexts as a Basis for Meaning-Making . 32 Recurring Themes in Wonderland . 33 Nature . 33 Time . 36 Reality . 38 Size . 40 Development of personal identity . 41 Historical Reactions to Wonderland . 43 The Future of Wonderland . 47 CHAPTER THREE: Curation as A METHODOLOGY . 53 Study Design and Purpose . 53
Peningkatan Keterampilan Membaca Melalui Drop Everything and Read (DEAR) pada Siswa Sekolah Dasar (MI)

Keterampilan membaca di sekolah dasar menjadi fondasi atau dasar penentu keberhasilan belajar siswa. Namun sayangnya, keterampilan membaca siswa sekolah dasar di Indonesia memiliki kecenderungan yang rendah. Hasil penelitian PIRLS menunjukkan bahwa keterampilan membaca siswa kelas IV SD di Indonesiamenempati urutan ke 41 dari 45 negara. Hasil penelitian EGRA menunjukkan bahwa 50% dari 4323 siswa kelas III SD di Indonesia dapat membaca (melek huruf), tetapi dari jumlah tersebut hanya setengahnya yang benar-benar memahami apa yang dibaca. Berdasarkan kenyataan tersebut diperlukan suatu upaya untuk meningkatkan keterampilan membaca siswa sekolah dasar (MI) di Indonesia. Salah satu upaya yang dapat dilakukan untuk meningkatkan keterampilan membaca siswa sekolah dasar (MI) adalah melalui DEAR (Drop Everything and Read) yang berarti tinggalkan semua aktivitas dan bacalah. DEAR dapat dijadikan suatu program penggalakan kebiasaan membaca pada siswa melalui program rutin. Pelaksanaan DEAR di sekolah dasar dapat dilakukan dengan meluangkan waktu sejenak di pagi hari sekitar 15-30 menit meninggalakan semua aktivitas untuk membaca. DEAR dilaksanakan oleh seluruh warga sekolah baik siswa, guru, maupun karyawan. Bahan bacaan dalam DEAR dipilih sendiri oleh siswa yang sesuai dengan minat dan tingkat kemampuannya. DEAR membuat siswa senang membaca, gemar membaca, terbiasa membaca, dan menjadikan membaca sebagai kebutuhan sehingga tercipta budaya membaca pada masing-masing siswa baik di lingkungan sekolah maupun di rumah. Melalui DEAR keterampilan membaca siswa akan meningkat.Kata kunci: membaca, DEAR
Antiplasmodial Activity of 80% Methanolic Extract and Solvent Fractions of Stem Bark of Acacia tortilis in Swiss Albino Mice

Background Malarial infection has significant negative impact on the health of the world population. It is treated by modern and traditional medicines. Among traditional medicinal plants, Acacia tortilis is used by different communities as antimalarial agent. Therefore, the objective of this study is to validate antimalarial activity of the stem bark of Acacia tortilis in mice. Methods To evaluate antimalarial activity of the plant, 4-day suppressive, curative, and prophylactic antimalarial test models were used. Parasitemia, packed cell volume (PCV), survival time, rectal temperature, and body weight were used to evaluate the effect of the plant extracts. Data were analyzed using SPSS version 26 followed by Tukey's post hoc multiple comparison test. Results The crude extract and dichloromethane fraction significantly suppressed the level of parasitemia (p < 0.001) and increased mean survival time (p < 0.01) at all tested doses. Similarly, significant effects were observed in mean survival time, % change of PCV, weight, and temperature in both curative and prophylactic antimalarial test models. Conclusions The methanolic extract and solvent fractions of the stem bark of Acacia tortilis has shown antimalarial activity, and the finding supports the traditional use and the in vitro studies. Thus, this study can be used as an initiation for researchers to find the most active phytochemical entity and to conduct additional safety and efficacy tests.
A multi-step transformation process for automatically generating indoor routing graphs from existing semantic 3 D building models

IndoorGML, a draft standard of the Open Geospatial Consortium (OGC), defines an information model for indoor space based on the requirements of indoor navigation. IndoorGML allows to represent, manage, and store different infrastructures of the indoor environment in primal (volumetric and boundary geometries) and dual (graph model) spaces along with semantic information. Furthermore, it provides a sound mathematical framework to derive, use, and manage parallel and hierarchical graph structures (layers) based on the different contextual considerations for the purpose of indoor navigation and information services. IndoorGML is not tightly coupled with a specific type of semantic 3D building model. Instead, existing standards for semantic 3D building models from the Building Information Modeling (BIM) and Topography Information Modeling (TIM) domains, namely the Industry Foundation Classes (IFC) and the City Geography Markup Language (CityGML) can be used in combination with IndoorGML. IndoorGML provides a unique platform for existing 3D semantic building models to integrate, manage, and to extend their horizon of applications with the other indoor thematic context spaces, e.g., sensor space. Therefore, there is a need to investigate the potential of integrating these different semantic building models with the IndoorGML model. This investigation goes beyond the conversion from one schema to the other; it also includes the concept of automatically deriving correct navigation structures for the indoor navigation with different types of locomotion. In this work, we describe a multi-step transformation process to automatically generate IndoorGML datasets from existing indoor building model data given in either IFC or CityGML LoD4. Moreover, we address semantic transformations, geometric transformations, topologic analyses, and spatial reasoning in order to derive navigation structures for the different types of locomotion. We tested our methods with a complex public building. In addition to the description of our conceptual work, this paper documents the lessons we learned from this test.
EVALUANDO UNA EXPERIENCIA DE APRENDIZAJE SERVICIO EN TORNO AL APRENDIZAJE DE CONCEPTOS DE LA CIUDADANÍA DIGITAL

Este articulo describe la aplicacion del aprendizaje servicio como metodologia de ensenanza en estudiantes de pregrado, contribuyendo a la diseminacion del concepto de ciudadania digital en la comunidad de la zona de influencia de la Universidad de La Sabana (Colombia). En este estudio participaron 81 estudiantes universitarios que impartieron varios talleres en dos instituciones publicas de los municipios aledanos a la Universidad. Estos talleres implicaban la creacion de materiales digitales y multimedia que fueron construidos en la materia Competencias Basicas Digitales y que fueron impartidos a 540 escolares. Al finalizar el proyecto se realizo un cuestionario para determinar la percepcion de los estudiantes frente a la experiencia. Para conocer la fiabilidad y la consistencia de este instrumento se aplicaron los estadisticos de Alfa de Cronbach obteniendose un valor de 0.726. El instrumento tambien incluyo preguntas abiertas para complementar los resultados de analisis estadistico. Los resultados muestran que esta metodologia incentivo en los estudiantes universitarios la apropiacion de los conceptos vistos en la materia, el refuerzo con relacion a sus practicas eticas frente a la tecnologia y una mayor sensibilidad social.
High potency multistrain probiotic improves liver histology in non-alcoholic fatty liver disease (NAFLD): a randomised, double-blind, proof of concept study

Objective Pharmacological treatment of non-alcoholic fatty liver disease (NAFLD) is still evolving. Probiotics could be a promising treatment option, but their effectiveness needs to be established. The present study aimed to evaluate the efficacy of a high potency multistrain probiotic in adult patients with NAFLD. Methods Thirty-nine liver biopsy-proven patients with NAFLD were randomised in a double-blind fashion to either lifestyle modifications plus an oral multistrain probiotic (675 billion bacteria daily, n=19) or identical placebo (n=20) for 1 year. Lifestyle modifications included regular exercise for all and control of overweight/obesity (with additional dietary restrictions), hypertension and hyperlipidaemia in those with these risk factors. Primary objective of the study was the histological improvement in NAFLD activity score (NAS) and its components and secondary objectives were improvement in alanine transaminase (ALT) and cytokine profile. Results Thirty (76.9%) out of 39 patients with NAFLD completed the study with 1 year of follow-up. A repeat liver biopsy at 1 year could be done in 10 patients (52.6%) in probiotic group and five patients (25%) in placebo group. In comparison to baseline, hepatocyte ballooning (p=0.036), lobular inflammation (p=0.003) and NAS score (p=0.007) improved significantly at 1 year in the probiotic group. When compared with placebo, the NAS score improved significantly in the probiotic group (p=0.004), along with improvements in hepatocyte ballooning (p=0.05) and hepatic fibrosis (p=0.018). A significant improvement in levels of ALT (p=0.046), leptin (p=0.006), tumour necrosis factor-α (p=0.016) and endotoxins (p=0.017) was observed in probiotic group in comparison to placebo at 1 year. No significant adverse events were reported in the study. Conclusion Patients with NAFLD managed with lifestyle modifications and multistrain probiotic showed significant improvement in liver histology, ALT and cytokines. Trial registration number The clinical trial is registered with CLINICAL TRIAL REGISTRYINDIA (CTRI); http://ctri.nic. in, No. CTRI/2008/091/000074
Structural and functional analysis of the Acinetobacter baumannii BlsA photoreceptor and regulatory protein

The Acinetobacter baumannii BlsA photoreceptor has an N-terminal (NT) BLUF domain and a C-terminal (CT) amino acid sequence with no significant homology to characterized bacterial proteins. In this study, we tested the biological role of specific residues located in these BlsA regions. Site-directed mutagenesis, surface motility assays at 24°C and protein overexpression showed that residues Y7, Q51 and W92 are essential for not only light-regulated motility, but also BlsA’s solubility when overexpressed in a heterologous host. In contrast, residues A29 and F32, the latter representing a difference when compared with other BLUF-containing photoreceptors, do not play a major role in BlsA’s biological functions. Analysis of the CT region showed that the deletion of the last five BlsA residues has no significant effect on the protein’s light-sensing and motility regulatory functions, but the deletion of the last 14 residues as well as K144E and K145E substitutions significantly alter light-regulated motility responses. In contrast to the NT mutants, these CT derivatives were overexpressed and purified to homogeneity to demonstrate that although these mutations do not significantly affect flavin binding and photocycling, they do affect BlsA’s photodynamic properties. Notably, these mutations map within a potential fifth α-helical component that could play a role in predicted interactions between regulatory partners and BlsA, which could function as a monomer according to gel filtration data. All these observations indicate that although BlsA shares common structural and functional properties with unrelated photoreceptors, it also exhibits unique features that make it a distinct BLUF photoreceptor.
Evaluation of canine 2D cell cultures as models of myxomatous mitral valve degeneration

The utility of cells cultured from the mitral valve as models of myxomatous diseases needs to be properly validated. In this study valve interstitial cells (VICs) and valve endothelial cells (VECs) were cultured from normal and diseased canine mitral valves in 2% (v/v) or 10% FBS media, in the presence of TGFβ1, 2 and 3, the TGFβ RI kinase inhibitor SB431542 and TGFβ neutralising antibodies, 5HT and the 5HT2RB antagonist LY272015. Cultures were examined by morphology, transcriptomic profiling, protein expression of the cell specific markers αSMA and SM22α (VICs), and CD31 (VECs), deposition of proteoglycans (PG), the PG versican, and the TGFβs themselves. VECs derived from normal valves were CD31+/αSMA-, but those from diseased valves were αSMA+, indicating endothelial-to-mesenchymal (EndoMT) transition had occurred. The TGFβs induced EndoMT in normal VECs, and this was abolished by SB431542, with significant changes in αSMA, CD31 and HAS2 expression (P<0.05). Normal VICs cultured in 10% FBS media were αSMA+ (activated myofibroblast (disease) phenotype), but were αSMA- when grown in 2% FBS. VICs from diseased dogs were αSMA+ in 2% FBS (retention of the activated myofibroblast disease phenotype), with significantly increased TGFβ1 expression (P<0.05) compared to normal cells. Treatment of normal and diseased VICs with the TGFβs significantly increased expression of αSMA, SM22α, versican, the TGFβs themselves, and deposition of PGs (P<0.05), with TGFβ1 being the most potent activator. These effects were either abolished or markedly reduced by SB431542 and a pan-TGFβ neutralizing antibody (P<0.05). SB431542 also markedly reduced αSMA expression in VICs from diseased valves, but 5HT and LY272015 had no effect on VIC phenotype. Transcriptomic profiling identified clear differences in gene expression for the different conditions and treatments that partially matched that seen in native diseased valve tissue, including changes in expression of ACTA2 (αSMA), 5HTR2B, TAGLN (SM22α) and MYH10 (SMemb), gene ontology terms and canonical signalling pathways. Normal and diseased VICs and normal VECs from canine mitral valves can be successfully grown in culture with retention of phenotype, which can be manipulated using TGFβ1 and the TGFβ RI kinase inhibitor SB431542. This optimized cell system can now be used to model MMVD to elucidate disease mechanisms and identify key regulators of disease progression.
Influence of chronic exposure to thiamethoxam and chronic bee paralysis virus on winter honey bees

Co-exposure to pesticides and viruses is likely to occur in honey bee colonies. Pesticides can be present in pollen, nectar, and persist in stored food (honey and bee bread), and viruses can be highly prevalent in honey bee colonies. Therefore, the present study describes the influence of chronic co-exposure to thiamethoxam and Chronic bee paralysis virus (CBPV) on bee survival, virus loads, expression level of immune and detoxication genes, and pesticide metabolism Experiments were performed on honey bees collected from a winter apiary with reduced viral contaminations. No synergistic effect of co-exposure was observed on bee survival, nor on the ability of bees to metabolise the pesticide into clothianidin. However, we found that co-exposure caused an increase in CBPV loads that reached the viral levels usually found in overt infections. The effect of co-exposure on CBPV replication was associated with down-regulation of vitellogenin and dorsal-1a gene transcription. Nevertheless, the observed effects might be different to those occurring in spring or summer bees, which are more likelyco-exposed to thiamethoxam and CBPV and exhibit a different physiology.