Miracle-dz/UniFAR-FTUs huggingface dataset:
SERUM AND URINARY MARKERS OF EARLY IMPAIRMENT OF GFR IN 1 CHRONIC KIDNEY DISEASE PATIENTS: DIAGNOSTIC ACCURACY OF 2 URINARY BETA-TRACE PROTEIN

26 The screening for chronic kidney diseases (CKD) patients with impaired GFR needs the 27 measurement of serum creatinine (SCr) or cystatin C (SCys). GFR can also be predicted from 28 SCr or SCys with different formulas. Aim of this study, performed in a group of CKD 29 patients with different levels of GFR, was to evaluate the possibility to select the patients with 30 a GFR < 90 mL/min/1.73 m, by means of serum levels and urinary excretion of different 31 low molecular weight proteins (LMWP), cystatin C (Cys), β2-microglobulin (β2M), retinol32 binding protein (RBP), beta-trace protein (BTP), and by means of the derived prediction 33 equations for GFR. 34 In the 295 CKD patients (females 137), at all stages of GFR impairment, a very high 35 correlation was found between GFR (Tc-DTPA), and serum Cr, Cys, β2M, and BTP. All 36 these serum markers showed a similar accuracy as indicators of different GFR impairments. 37 RBP had the lowest correlation with GFR, and was also significantly less accurate. The 38 different prediction formulas derived from gender, anthropometric data and SCr or S-LMWP 39 had a diagnostic accuracy similar to that of serum Cr, Cys, β2M, and BTP. Urinary albumin 40 was inadequate as indicator of any level of GFR impairment. Urinary excretion of Cys and 41 β2M increased significantly only in patients with GFR<30 ml/min/1.73m, while urinary BTP 42 increased already at GFR<90 ml/min/1.73m. In this selected group of CKD patients, the 43 positive predictive value of urinary BTP for GFR<90 ml/min/1.73m was 85%, indicating 44 that, in CKD patients, a urine-based test can predict a slight GFR impairment. 45 46
GRAPH CONVOLUTIONAL RECURRENT NETWORKS

This paper introduces Graph Convolutional Recurrent Network (GCRN), a deep learning model able to predict structured sequences of data. Precisely, GCRN is a generalization of classical recurrent neural networks (RNN) to data structured by an arbitrary graph. Such structured sequences can represent series of frames in videos, spatio-temporal measurements on a network of sensors, or random walks on a vocabulary graph for natural language modeling. The proposed model combines convolutional neural networks (CNN) on graphs to identify spatial structures and RNN to find dynamic patterns. We study two possible architectures of GCRN, and apply the models to two practical problems: predicting moving MNIST data, and modeling natural language with the Penn Treebank dataset. Experiments show that exploiting simultaneously graph spatial and dynamic information about data can improve both precision and learning speed.
PERMAINAN ULAR TANGGA DALAM MENGINGKATKAN KEMAMPUAN MORAL ANAK

Abstract - Moral religion is important to develop because it will become the basis or foundation of childrenin navigating life. From the observation of the age of 3-4 years at KOBER PGRI Bayah, it was found thatchildren's abilities in the aspects of religious moral development were relatively low. Based on the thinkingabout the factors causing the low moral capacity of the child's religion are: (1) teacher's body language is stilldifficult so that the presentation of learning is less interesting; (2) the use of methods that are less varied; (3)the lack of teaching aids owned; (4) avoiding children's interest in religious moral learning. This research usesClassroom Action Research. The results of the study show how to learn that can improve the moral capacityof religious children aged 3-4 years at KOBER PGRI Bayah, Lebak Regency. The success rate for activitiesis very significant. In the pre-cycle activities of the average percentage of 38.67% increased to 55.67% in thefirst cycle, and increased to 90.33% in the second cycle.Keywords - kemampuan moral agama, game ular tangga
Positive curvature and symmetry in small dimensions

Extending existing work in small dimensions, Dessai computed the Euler characteristic, signature, and elliptic genus for [Formula: see text]-manifolds of positive sectional curvature in the presence of torus symmetry. He also computes the diffeomorphism type by restricting his results to classes of manifolds known to admit non-negative curvature, such as biquotients. The first part of this paper extends Dessai’s calculations to even dimensions up to [Formula: see text]. In particular, we obtain a first characterization of the Cayley plane in such a setting. The second part studies a closely related family of manifolds called positively elliptic manifolds, and we prove a conjecture of Halperin in this context for dimensions up to [Formula: see text] or Euler characteristics up to [Formula: see text].
Motivations, success, and cost of coral reef restoration

Coral reef restoration is an increasingly important part of tropical marine conservation. Information about what motivates coral reef restoration as well as its success and cost is not well understood but is needed to inform restoration decisions. We systematically review and synthesize data from mostly scientific studies published in peer‐reviewed and gray literature on the motivations for coral reef restoration, the variables measured, outcomes reported, the cost per hectare of the restoration project, the survival of restored corals, the duration of the project, and its overall spatial extent depending on the restoration technique employed. The main motivation to restore coral reefs for the projects assessed was to further our ecological knowledge and improve restoration techniques, with coral growth, productivity, and survival being the main variables measured. The median project cost was 400,000 US$/ha (2010 US$), ranging from 6,000 US$/ha for the nursery phase of coral gardening to 4,000,000 US$/ha for substrate addition to build an artificial reef. Restoration projects were mostly of short duration (1–2 years) and over small spatial extents (0.01 ha or 108 m2). Median reported survival of restored corals was 60.9%. Future research to survey practitioners who do not publish their discoveries would complement this work. Our findings and database provide critical data to inform future research in coral reef restoration.
Ten Year Review of Pulmonary Nocardiosis: A Series of 55 Cases

Introduction Nocardiosis is a rare opportunistic bacterial infection usually seen in immunosuppressed patients. It is caused by gram-positive, aerobic actinomycetes of the Nocardia genus. The most common site of infection is lungs; but it may affect other organs or even disseminate into blood. Methods In this a 10-year retrospective review, all diagnosed cases of Pulmonary Nocardiosis in a tertiary care hospital were included. The clinical and radiological characteristics, course of complications and lifesaving interventions, and disease outcome were evaluated. Results Among the 55 identified cases, most common risk factor was chronic steroid therapy (n=38; 69.1%). Among respiratory diseases, chronic obstructive pulmonary disease (n=13; 23.6%) and tuberculosis (n=12; 21.8%) were the most common. On chest radiograph, pleural effusion (n=23; 41.8%) and consolidation (n=22; 40.0%) were the common findings. Complications were observed in 32 (58.2%) patients with septicemia and respiratory failure being the most common (n=15; 46.8% in each). Dissemination occurred in 10 (31.2%) patients. The mortality rate of Nocardia is 34.5% (n=19). Conclusion The disease burden of Nocardia is underestimated by clinicians and researchers. Pulmonary Nocardia should always be a differential diagnosis of signs of lower respiratory tract infection and must be excluded in patients not responding to treatment of chronic obstructive pulmonary disease (COPD) and pulmonary tuberculosis. Early recognition and individualized management plan can ensure successful recovery.
Promoting zero emissions buses programs: A study of Ekaterinburg residents’ willingness to pay

Transports are among the major sources of atmospheric pollution, causing climate change and public health damage. Public transportation is a well-known, recognized solution to greatly decrease transport emissions, especially when making use of zero emissions buses in the fleet, such as buses driven by batteries or by hydrogen. However, cost imposes a large barrier on zero emissions buses. The transition to the use of such buses is expensive, and it must be driven by several stakeholders, thus motivating service providers to make efforts towards zero emissions buses implementation strategies. In this study, citizens from a Russian district capital city were questioned on their potential role as contributors to the zero emissions buses transition, by studying their willingness and attitudes to pay a premium for the bus fares, in order to supplement the public transport agencies revenues. It was found that environmental concern and air pollution concern can be critical factors driving consumers into paying premium, but not noise pollution. Based on this study, there are several recommendations proposed for practitioners, as well as several future research avenues. In this article we seek to investigate how the consumers’ attitudes and concerns over the environment and city pollution could influence their willingness to play a role as supporters of the introduction of zero emissions buses in the public transportation fleet, since understanding the consumer attitudes is essential to perform and run an efficient public system.
Incidental News Exposure on Social Media: A Campaign Communication Mediation Approach

This study, derived from campaign communication mediation models, examines how incidental news exposure on social media affects political participation. Analysis of two-wave panel data collected before the 2016 US presidential election shows that incidental news exposure on social media is associated with increases in offline and online political participation (1) through online political information seeking and (2) through online political information seeking and online political expression in serial. Interestingly, results show that incidental news exposure on social media also has a direct negative relationship with offline and online political participation. Implications for the political utility of social media are discussed.
Organizational Change and Job Satisfaction: An Analysis of Mediating Effect of Organizational Trust

Organizational change is a growing area of importance for modern organizations’ strategic development. Effective organizational change is imperative for the success of competitive organizations. The available theory conceptualizes that organizations have realized the equal importance of job satisfaction and organizational trust as a mean to gain and sustain competitive advantage. Therefore, an attempt has been made to study the relationship among three variables of the study viz; organizational change, job satisfaction and organizational trust, and to analyse the mediating effect of organizational trust on the relationship of organizational change and job satisfaction. The analysis has been done on the basis of primary and secondary data. The primary data has been collected from 150 respondents of an IT company with the help of three standardized questionnaires. The hypotheses have been tested using correlation and regression analysis. The findings based on correlation analysis confirm a positive and significant relationship between organizational trust and job satisfaction (r=0.62); organizational trust and organizational change (r=0.74) and organizational change and job satisfaction (r=0.52). Furthermore, the results of regression analysis shows that organizational trust exerts a mediating effect on the relationship of organizational change and job satisfaction (β=.264; p<.01; Adjusted R2 =.112). The study concludes that organizational change should be carried out in an atmosphere of mutual trust. It further leads to the formation of an affective bond between the organization and employees, which in turn, leads to job satisfaction.
Beliefs, Doubts and Learning: Valuing Macroeconomic Risk

within a rational expectations model from two perspectives: that of an econometrician and that of the economic agents within the model. The assumption of rational expectations has been and remains an important component to quantitative research. It endows economic decision makers with knowledge of the probability law implied by the economic model. As such, it is an equilibrium concept. Imposing rational expectations removed from consideration the need for separately specifying beliefs or subjective components of uncertainty. Thus, it simplified model specification and implied an array of testable implications that are different from those considered previously. It reframed policy analysis by questioning the effectiveness of policy levers that induce outcomes that differ systematically from individual beliefs. I consider two related problems. The first is the problem of an econometrician who follows John F. Muth (1961), Robert E. Lucas, Jr., and Edward C. Prescott (1971), Lucas (1972a), Thomas J. Sargent (1973), and an extensive body of research by adopting an assumption of rational expectations on the part of economic agents. In implementing this approach, researchers abstract from hard statistical questions that pertain to model specification and estimation. The second problem is that of economic decision makers or investors who must forecast the future to make RichaRd T. Ely lEcTuRE
Effect of Occupational Safety and Health and Incentives on Work Motivation and Employee Performance (Study in Employees of PT. YTL-Paiton Province East Java)

This research in PT YTL and was conducted to determine the effect of independent variables namely Occupational safety, Occupational Health, and Incentives on the dependent variable namely Employee Performance through the intervening variable namely Work Motivation. This research is a type of explanatory research with a quantitative approach. The data used in this study are primary data obtained from questionnaires. The researcher used probability sampling techniques, namely proportionate random sampling using Slovin formula and obtained a sample of 78 respondents. Data analysis in this study used the Path Analysis method with the help of SPSS. The results of this study indicate that Occupational Safety, Occupational Health, and Incentives are positive and significantly influence the Work Motivation. Variable work motivation is a positive and significant effect on employee performance. Furthermore, Occupational Safety, Occupational Health, and Incentives are positive and significantly influence Employee Performance. Furthermore, there are indirect effects between the variables of Occupational Safety, Occupational Health, and Incentives on Employee Performance through Work Motivation variables.
Expression of PD-L1 in cervical carcinoma and its impact on survival associated with T-cell infiltration and FoxP3 expression

Background: The PD-1/PD-L1 signaling axis is currently the most elucidated mechanism for tumor evasion of T-cell-mediated immunity. Nevertheless, few data are available regarding its impact on cervical cancer and the relationship with lymphocytic infiltrates. Methods: A retrospective assessment of all cases of cervical neoplasia treated in Caxias do Sul General Hospital, Brazil, between 2012 and 2016 was performed. Clinical and pathological data were collected from electronic records and analyzed. Original slides were independently reviewed by three pathologists to confirm diagnoses and to assess the immunohistochemical expression of PD-L1 and FoxP3 in tumor cells and lymphocytic infiltrates. Results: PD-L1 staining was present in 32.2% of the 59 cervical samples. Median overall survival time of the PD-L1-negative group was 47.8 months, a time point not yet reached by the PD-L1-positive group (p=0.968). Median progression-free survival was 24.3 months for PD-L1-negative and 11.5 months for PD-L1-positive patients (p=0.263). PD-L1 staining was found in 27.1% of the lymphocytic infiltrates, and survival analysis revealed no difference between PD-L1-positive and PD-L1-negative samples. There was no impact on survival related to FoxP3 staining in neither tumor samples nor lymphocytic infiltrates. Conclusion: Although the median progression-free survival times differed, the difference was not statistically significant. Our study corroborates the rationale that PD-L1 expression in cervical neoplasms has no impact on survival. PD-L1 expression in peritumoral lymphocytes revealed no impact on infiltration volume nor survival. Keywords: uterine cervical neoplasms, tumor-infiltrating lymphocytes, cancer, tumor microenvironment, survival
Can perineal tear be predicted by severity of striae gravidarum score?

Background: The objective of this study was to wether perineal tear predicted by scoring of severity of striae gravidarum. The objective of this study was to predict perineal tear by simple non-invasive method and help to prevent maternal morbidity.Methods: Three hundred ninety four patients delivered normally were included in this study. Striae gravidarum score was assessed using the Atwal numerical scoring system. The association was examined between striae and perineal tear as the outcome measure, defined by tears or laceration, and the total striae scores (TSS) was obtained.Results: In present study population mean age was 25.16 years ranging from 16-40 , mean gravidity was 2.16 ranging from 1 -8 ,average baby birth weight was 2.713 kg ranging from 1.62-4.58 The only predictors of perineal tears that were found to be statistically significant in our study were severity of striae gravidarum and episiotomy given or not. In patients with moderate to severe striae there was tear in 90 patients as compared to 29 patients with no or mild striae. 224 patients belonging to no or mild striae group delivered without any perineal tear whereas 51 patients in moderate to severe striae group delivered without tear. Out of these 51 patients 5 were given episiotomy. 2 patients who were given episiotomy had perineal tear as compared to 117 patients who were not given episiotomy. This shows that patients who had an episiotomy were less likely to have perineal tear in most cases.Conclusions: This study demonstrates a significant relation between severity of striae gravidarum and perineal tear. The findings suggest that striae gravidarum assessment may be used in the clinical setting even by paramedical staff as a simple and noninvasive tool to better define women at risk for perineal tear.
Award Number: W81XWH-12-1-0210 TITLE: Deconstruction of Oncogenic K-RAS Signaling Reveals Focal Adhesion Kinase as a Novel Therapeutic Target in NSCLC

s at national and international meetings: 1. G. Konstantinidou, G. Ramadori, F. Torti, C. Behrens, I. I. Wistuba, A. Heguy, D. Gerber, J. TeruyaFeldstein, P.P. Scaglioni. Identification of Focal Adhesion Kinase (FAK) as a Therapeutic Target in KRAS Mutant Lung Cancer. Mechanisms and Models of Cancer. Salk Institute, La Jolla, CA. August 7-1
Three complete plant-pollinator networks along a secondary successional gradient in critically endangered Renosterveld, South Africa

Despite the global recognition of the importance of pollination as an ecosystem function, there remains a dearth of community level studies on the African continent. Here we present three complete pollination networks, along a secondary successional gradient, in critically endangered Renosterveld vegetation within an agri-environment, South Africa. Site selection was based on historical land-use and contemporary vegetation data resulting in a pristine site, a late successional site where agriculture was halted >15 years ago, and an early successional site where agriculture was halted <five years ago. In total, 240 hours of pollinator-plant observations were recorded over a single flowering season. The pristine site was highly specialised in comparison to global datasets – most likely as a result of relative climatic stability through the Quaternary which allowed specialisation to manifest and persist. Both non-pristine sites showed noticeable differences in characteristics when expressed through network indices; however, the early successional site was closer in nature to the pristine site as a result of vegetation structure. Notwithstanding a lack of replication across the successional gradient precluding robust statistical analyses, this study provides important data which allows for the comparison of pollination dynamics in an understudied and vulnerable vegetation type, to plant-pollinator networks at the global and regional scale. In addition, apparent changes to network indices as a result of habitat alteration, suggest that successional trajectory plays an important role in pollination dynamics.
THE EFFECT OF BRAINSTORMING TECHNIQUEAS A PREWRITING ACTIVITY ON THE STUDENTS’ ACHIEVEMENT IN WRITING DESCRIPTIVES TEXTAT SMAN 1 PRINGSEWU

The aim of the study was to find out the effect of brainstorming technique on the students’ writing achievement. This research was conducted through a quantitative approach with one group pre-test and post-test design. The subject of the research were 33 students of X MIA 3 class at SMA Negeri 1 Pringsewu in 2018/2019 academic year. In this research, the researcher administered four meetings. The beginning of the meeting, the researcher conducted the pre-test to find out the students’ initial ability in writing descriptive text. Then, the researcher had two time meetings of the treatments. At the end of the meeting, the researcher conducted the post test to find out the students’ writing ability after having the treatments which used brainstorming technique. The result of the students’ writing test was measured in terms of content, organization, grammar, vocabulary, and mechanic. The data were analyzed by using Paired Sample t-test in which the significance was determined by sign < 0.05. The result showed that there was a statistically significant difference of the students’ writing ability between the pre-test and the post-test with the significant level of 0.05. This suggests that brainstorming technique facilitates the students to improve their ability in writing skills. Therefore the hypotheses of the research which stated that there are some positive effects of brainstorming technique on the students writing achievement in five aspects of writing; content, organization, grammar, vocabulary, and mechanic was accepted. The mean score of pre-test was 62.48 and the mean score of post-test was 73.50. It means that the students’ mean score improved about 11.02. Form each aspect of writing, the aspect that improve the most was organization from 33.33 to 52.73. The score is increased by 19.4. Based on the findings, it can be concluded that brainstorming technique gave some positive effects on students’ writing achievement. Keywords: writing, writing ability, brainstorming technique.
Looking Back Again to the Brazilian Crises of the 1990s: The Role of Financial Derivatives

The presence of financial derivatives can be a very effective destabilizing factor in economies which are rapidly liberalized and which, especially, have poorly structured and improperly regulated imbalanced derivatives markets, like the emerging market economies, including Brazil in the 1990s. Since Brazil was subject to the rapid and almost complete liberalization of her economy in the 1990s, and had poorly structured imbalanced derivative markets, she was highly vulnerable to the harmful usages of financial derivatives in the 1990s. Although financial derivatives were initially developed for beneficial purposes, such as the handling of risks and volatilities, they turned into channels creating them. This paper aims to analyze and test statistically their potential role in the Brazilian financial crises in the 1990s through a time-series approach. The major findings indicate that they had an increasing impact on crisis pressures of Brazil in the 1990s, both in the short and long term. JEL Codes: F37, G01, G15