Miracle-dz/UniFAR-FTUs huggingface dataset:
Institutionalisation of Quality Assurance in an Ethiopian Public University

------------------------------------------------------------------------------------------------------i Acknowledgements---------------------------------------------------------------------------------------ii List of Tables and Figures-------------------------------------------------------------------------------vi Abbreviations----------------------------------------------------------------------------------------------vii Chapter One – Introduction 1.1. Background-------------------------------------------------------------------------------------------1 1.2. Statement of research problem-------------------------------------------------------------------3 1.2.1. Research gap-------------------------------------------------------------------------------------3 1.2.2. Research question------------------------------------------------------------------------------4 1.3. Scope of the study-----------------------------------------------------------------------------------5 1.4. Significance of the study---------------------------------------------------------------------------5 1.5. Research methodology-----------------------------------------------------------------------------6 1.5. 1. Study design-------------------------------------------------------------------------------------6 1.5. 2. Case university selection---------------------------------------------------------------------6 1.5. 3. Data collection----------------------------------------------------------------------------------7 1.5. 4. Method of data analysis----------------------------------------------------------------------9 1.5. 5. Validity and reliability-----------------------------------------------------------------------10 1.5. 6. Ethical consideration-------------------------------------------------------------------------11 1.6. Structure of the thesis-----------------------------------------------------------------------------12 Chapter Two – Analytical Framework: Institutionalisation of Quality Assurance 2.1. Rationale---------------------------------------------------------------------------------------------13 2.2. The essential elements for institutionalising quality assurance------------------------15 2.3. Phases of institutionalisation-------------------------------------------------------------------19 Chapter Three The Concept of Quality and Quality Assurance 3.1. The debate: What really is quality? ----------------------------------------------------------23
Pengaruh Komponen Keahlian terhadap Kemampuan Auditor dalam Pendeteksian Kecurangan pada Auditor Bpkp Sumatera Barat

This study aimed to analyze the effect caused by the auditor’s skill component consist of knowledge component, experience, decision strategies, cognotive abilities, task analysis, and interpesonal skill with auditor’s ability on fraud detection. This study uses total sampling with 80 samples obtained from the all of auditor at BPKP West Sumatera. Data collection techniques in this study is in the form of questionnaires. Number of questionnaires returned was 42, while data analysis technique used is multiple regression analysis were processed with SPSS version 16 for Windows. The result of this research indicated that (1) knowledge component has no effect to the auditor’s ability on fraud detection where significant value 0,174>0,05 and
Challenges facing immediate tourism leveraging: evidence from the London 2012 Olympic Games

ABSTRACT Models of event leveraging identify strategies that organisers can use to increase the benefits that sport events bring to host destinations. Among these, leveraging tourism benefits during the event is a frequently cited strategy by which organisers can bring more money into a destination. To date, little work has been conducted on leveraging immediate tourism benefits from mega sport events. In addressing this issue, we reflect and present findings related to previously identified event leveraging theories that are determined by tourists’ activities at a host destination. These are (a) enticing visitor spending and (b) lengthening visitor stay. The aim of this paper is to evaluate the use of such leveraging strategies during the London 2012 Olympic Games to increase event-related tourism. Results from 15 interviews with key stakeholders demonstrate that the effectiveness of these leveraging strategies can be limited by a number of challenges: (1) limited strategies to entice visitor spending, (2) limited interest in tourism attractions, (3) lack of location attractiveness, (4) the displacement effect and (5) the impact of the wider economic environment. Key challenges and opportunities are detailed, a discussion on the implications for event leveraging is provided and potential areas for future research are outlined.
miRNA signature identification of retinoblastoma and the correlations between differentially expressed miRNAs during retinoblastoma progression

Purpose Retinoblastoma (RB) is a common pediatric cancer. The study aimed to uncover the mechanisms of RB progression and identify novel therapeutic biomarkers. Methods The miRNA expression profile GSE7072, which includes three RB samples and three healthy retina samples, was used. After data normalization using the preprocessCore package, differentially expressed miRNAs (DE-miRs) were selected by the limma package. The targets of the DE-miRs were predicted based on two databases, followed by construction of the miRNA–target network. Pathway enrichment analysis was conducted for the targets of the DE-miRNAs using DAVID. The CTD database was used to predict RB-related genes, followed by clustering analysis using the pvclust package. The correlation network of DE-miRs was established. MiRNA expression was validated in another data set, GSE41321. Results In total, 24 DE-miRs were identified whose targets were correlated with the cell cycle pathway. Among them, hsa-miR-373, hsa-miR-125b, and hsa-miR-181a were highlighted in the miRNA–target regulatory network; 14 DE-miRs, including hsa-miR-373, hsa-miR-125b, hsa-miR-18a, hsa-miR-25, hsa-miR-20a, and hsa-let-7 (a, b, c), were shown to distinguish RB from healthy tissue. In addition, hsa-miR-25, hsa-miR-18a, and hsa-miR-20a shared the common target BCL2L11; hsa-let-7b and hsa-miR-125b targeted the genes CDC25A, CDK6, and LIN28A. Expression of three miRNAs in GSE41321 was consistent with that in GSE7072. Conclusions Several critical miRNAs were identified in RB progression. Hsa-miR-373 might regulate RB invasion and metastasis, hsa-miR-181a might involve in the CDKN1B-mediated cell cycle pathway, and hsa-miR-125b and hsa-let-7b might serve as tumor suppressors by coregulating CDK6, CDC25A, and LIN28A. The miRNAs hsa-miR-25, hsa-miR-18a, and hsa-miR-20a might exert their function by coregulating BCL2L1.
Five preventable causes of kidney graft loss in the 1990s: a single-center analysis.

BACKGROUND Despite improvements in immunosuppressive protocols and patient care, kidney allografts continue to fail. We studied causes of graft loss for primary kidney transplants in the 1990s to determine major causes and potential interventions. METHODS Causes of graft loss were reviewed for 1467 primary kidney transplants done at our institution between January 1, 1990, and December 31, 1999. Graft loss for that entire population was studied and then the causes of loss selectively examined at <1 year, 1 to 5 years, and>5 years post-transplant. Finally, causes of loss in the 1990s versus the 1980s were compared. RESULTS Five major causes of graft loss were noted in the 1990s: thrombosis, acute rejection (either alone or combined with delayed graft function or infection), chronic rejection, death with function, and noncompliance. In the first year post-transplant, thrombosis (25%) and death with function (41%) were the major causes of graft loss. After the first year, chronic rejection and death with function predominated. For recipients dying with graft function, cardiovascular disease was the major cause of death. CONCLUSIONS This study identified the five major causes of kidney graft loss in the 1990s. Different interventions are required to decrease loss from each of these causes. Future research needs to be directed at such interventions.
Roles of women in agriculture: A case study of rural Lahore, Pakistan

In rural areas of Pakistan, the role of women in agriculture is more pronounced because they contribute a lot to agriculture, but their contribution in agriculture is not acknowledged. The present study was designed in rural union councils of three towns of Lahore, Pakistan namely Nishatar Town, Iqbal Town and Wahga Town. A questionnaire was designed to collect the data from rural women (n=207). Results reveals that a majority of women (42.02%) started the work at 29 to 39 years of age and mostly (86.95%) they were illiterate. A majority of the respondents (81.64%) were getting agricultural information from their own family members, and 56.52% rural women worked 8-10 hours per day. During this study, it was also found that wheat and rice were the major crops sown by all the respondents (100%). Out of all the pre-harvesting activities, 94.2% positive responses were recorded against seed bed preparation. A majority of rural women (85.02, 88.88 and 95.65%) were involved in shed cleaning, dung collection and fodder cutting, respectively. Thirty-one percent of rural women reported that limited agricultural product was the main cause for not being involved in agricultural marketing. Among the problems of household activities, 43.5% rural women reported that husband wife conflicts were the major problem in their life. Need assessment analysis reveals that rural women presented the highest need of trainings (85.5%) to improve their role in agricultural activities. This study suggests that concerted efforts of government and non-government agencies are required to uplift these rural women.
Poor glycemic control is an independent risk factor for low HDLC in patients with type 2 diabetes

1 Department of Clinical Sciences, Sapienza University of Rome, Rome, Italy 2 Unit of Endocrinology, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy 3 Department of Clinical and Experimental Medicine, “Magna Græcia” University, Catanzaro, Italy 4 Department of Medical Pathophysiology, Sapienza University of Rome, Rome, Italy 5 Research Unit of Diabetes and Endocrine Diseases, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy 6 IRCCS Casa Sollievo della Sofferenza-Mendel, Rome, Italy
Sociodemographic and drug use severity differences between medical marijuana users and non-medical users visiting the emergency department.

BACKGROUND AND OBJECTIVES The purpose of this study is to extend what is known about medical marijuana and non-medical marijuana users who visit the emergency department (ED) by exploring differences in their sociodemographic characteristics and their drug-related problem severity. METHODS Of 292 consecutively enrolled exclusive marijuana-only users visiting the ED for any reason, 37% (n = 107) reported using marijuana on the advice of a medical doctor, and 63% (n = 185) reported that they did not use it under the advice of a medical doctor (ie, non-medical user). Participants denied using any other drug with the exception of alcohol. Participants completed the Addiction Severity Index-Lite which provided composite and individual items related to drug use problems, psychiatric problems, medical problems, and alcohol use problems. Self-efficacy for avoiding drug use and sociodemographic characteristics were also collected. RESULTS In a multivariate model, compared to non-medical marijuana users, medical users reported a higher frequency of days of use, more money spent on marijuana, and lower readiness to change use of marijuana, yet lower frequency of drug problems and tended to be low-risk versus moderate-severe risk users. Medical marijuana use was associated with a greater number of days of psychological problems. DISCUSSION AND CONCLUSIONS Results for medical marijuana users might be interpreted as consistent with that of routine, self-administered treatment for medical or psychological problems. SCIENTIFIC SIGNIFICANCE Results suggest behavioral health interventions in acute care settings should consider treating non-medical marijuana users differently than medical users due to the greater drug-related problems associated with non-medical use. (Am J Addict 2016;25:385-391).
Object Interaction as a Central Component of Object-oriented System Analysis

An increasing impact of system modeling in software development facilitates a vision of software development methodology. Currently one of the leading positions has OMG and its solution for system abstraction, modeling, development, and reuse – Model Driven Architecture (MDA). A key component of system modeling under principles of MDA is Unified Modeling Language (UML), which defines several kinds of diagrams and their notation. System modeling is an important part of system analysis and design, where MDA proposes to use means of automatic code generation. UML offers to use system presentation as interacting objects and offers to model two kinds of object interaction diagram, namely, sequence and communication. The paper focuses on investigation of analysis, modeling, and design of object interaction and discusses the ability to increase the level of formalization in modeling of object in-
Targeted Identification of Short Interspersed Nuclear Element Families Shows Their Widespread Existence and Extreme Heterogeneity in Plant Genomes[W]

Plant genomes contain a large number of short interspersed nuclear elements, which so far have been detected only randomly. A software tool was created integrating weakly conserved structural motifs for the analysis of genome sequences. Thousands of sequences from many plant taxa were identified, giving insights into their variability, localization along chromosomes, and evolution. Short interspersed nuclear elements (SINEs) are non-long terminal repeat retrotransposons that are highly abundant, heterogeneous, and mostly not annotated in eukaryotic genomes. We developed a tool designated SINE-Finder for the targeted discovery of tRNA-derived SINEs. We analyzed sequence data of 16 plant genomes, including 13 angiosperms and three gymnosperms and identified 17,829 full-length and truncated SINEs falling into 31 families showing the widespread occurrence of SINEs in higher plants. The investigation focused on potato (Solanum tuberosum), resulting in the detection of seven different SolS SINE families consisting of 1489 full-length and 870 5′ truncated copies. Consensus sequences of full-length members range in size from 106 to 244 bp depending on the SINE family. SolS SINEs populated related species and evolved separately, which led to some distinct subfamilies. Solanaceae SINEs are dispersed along chromosomes and distributed without clustering but with preferred integration into short A-rich motifs. They emerged more than 23 million years ago and were species specifically amplified during the radiation of potato, tomato (Solanum lycopersicum), and tobacco (Nicotiana tabacum). We show that tobacco TS retrotransposons are composite SINEs consisting of the 3′ end of a long interspersed nuclear element integrated downstream of a nonhomologous SINE family followed by successfully colonization of the genome. We propose an evolutionary scenario for the formation of TS as a spontaneous event, which could be typical for the emergence of SINE families.
Supply chain design modeling at Philips Healthcare

Disclaimer This document contains a student thesis (bachelor's or master's), as authored by a student at Eindhoven University of Technology. Student theses are made available in the TU/e repository upon obtaining the required degree. The grade received is not published on the document as presented in the repository. The required complexity or quality of research of student theses may vary by program, and the required minimum study period may vary in duration.
Biochemical effects of profenofos residues in potatoes.

Foliar application of profenofos was made onto potato plants 1 month before harvest. Determination of profenofos residues in fresh and processed potatoes was carried out. The detected levels were 11.48, 0.24, 0.22, 0.19, 0.004, and 0.16 mg/kg for fresh, frosen, microwave-baked, oven-baked, and french fried potatoes and potato peels, respectively. The profenofos residues induced the levels of transaminases (GOT and GPT). However, the GOT/GPT ratio was decreased. Little increase was observed in acid phosphatase (APase) activity
The Competitive Landscape of High-Frequency Trading Firms

We examine product differentiation in the high-frequency trading (HFT) industry, where the “products” are secretive proprietary trading strategies. We demonstrate how principal component analysis can be used to detect underlying strategies common to multiple HFT firms and show that there are three product categories with distinct attributes. We study how HFT competition in each product category affects the market environment and present evidence that indicates how it influences the short-horizon volatility of stocks as well as the viability of trading venues. Received October 10, 2016; editorial decision September 30, 2017 by Editor Itay Goldstein. Authors have furnished an Internet Appendix, which is available on the Oxford University Press Web site next to the link to the final published paper online.
Project on the Good Physician: Further Evidence for the Validity of a Moral Intuitionist Model of Virtuous Caring

ABSTRACT Theory: In the Project on the Good Physician, the authors propose a moral intuitionist model of virtuous caring that places the virtues of Mindfulness, Empathic Compassion, and Generosity at the heart of medical character education. Hypotheses: Hypothesis 1a: The virtues of Mindfulness, Empathic Compassion, and Generosity will be positively associated with one another (convergent validity). Hypothesis 1b: The virtues of Mindfulness and Empathic Compassion will explain variance in the action-related virtue of Generosity beyond that predicted by Big Five personality traits alone (discriminant validity). Hypothesis 1c: Virtuous students will experience greater well-being (“flourishing”), as measured by four indices of well-being: life meaning, life satisfaction, vocational identity, and vocational calling (predictive validity). Hypothesis 1d: Students who self-report higher levels of the virtues will be nominated by their peers for the Gold Humanism Award (predictive validity). Hypothesis 2a–2c: Neuroticism and Burnout will be positively associated with each other and inversely associated with measures of virtue and well-being. Method: The authors used data from a 2011 nationally representative sample of U.S. medical students (n = 499) in which medical virtues (Mindfulness, Empathic Compassion, and Generosity) were measured using scales adapted from existing instruments with validity evidence. Results: Supporting the predictive validity of the model, virtuous students were recognized by their peers to be exemplary doctors, and they were more likely to have higher ratings on measures of student well-being. Supporting the discriminant validity of the model, virtues predicted prosocial behavior (Generosity) more than personality traits alone, and students higher in the virtue of Mindfulness were less likely to be high in Neuroticism and Burnout. Conclusions: Data from this descriptive-correlational study offered additional support for the validity of the moral intuitionist model of virtuous caring. Applied to medical character education, medical school programs should consider designing educational experiences that intentionally emphasize the cultivation of virtue.
Intralymphatic allergen administration renders specific immunotherapy faster and safer: A randomized controlled trial

The only causative treatment for IgE-mediated allergies is allergen-specific immunotherapy. However, fewer than 5% of allergy patients receive immunotherapy because of its long duration and risk of allergic side effects. We aimed at enhancing s.c. immunotherapy by direct administration of allergen into s.c. lymph nodes. The objective was to evaluate safety and efficacy compared with conventional s.c. immunotherapy. In a monocentric open-label trial, 165 patients with grass pollen-induced rhinoconjunctivitis were randomized to receive either 54 s.c. injections with pollen extract over 3 years [cumulative allergen dose 4,031,540 standardized quality units (SQ-U)] or 3 intralymphatic injections over 2 months (cumulative allergen dose 3,000 SQ-U). Patients were evaluated after 4 months, 1 year, and 3 years by nasal provocation, skin prick testing, IgE measurements, and symptom scores. Three low-dose intralymphatic allergen administrations increased tolerance to nasal provocation with pollen already within 4 months (P < 0.001). Tolerance was long lasting and equivalent to that achievable after standard s.c. immunotherapy (P = 0.291 after 3 years). Intralymphatic immunotherapy ameliorated hay fever symptoms (P < 0.001), reduced skin prick test reactivity (P < 0.001), decreased specific serum IgE (P < 0.001), caused fewer adverse events than s.c. immunotherapy (P = 0.001), enhanced compliance (P < 0.001), and was less painful than venous puncture (P = 0.018). In conclusion, intralymphatic allergen administration enhanced safety and efficacy of immunotherapy and reduced treatment time from 3 years to 8 weeks.
Exploring value co-creation in Fan Fests: the role of fans

Abstract Fan Fests have recently provided various opportunities for host cities, organizers, sponsors and fans, manifesting a modern intersected third place service setting (other than a stadium) where varied stakeholders can co-create value and sport experience and consumption can take different forms and shapes. Yet, although Fan Fests are becoming integral parts of mega-events, research has fallen short of capturing the unique nature of such value co-creation ecosystem, and the role of fans in such value co-creation environment. This paper takes up this challenge and explores the still evolving nature of the Fan Fest, using a primarily consumer and participant focused approach in order to explore the experiences of a Fan Fest and address questions of event construction, participation, organization and consumption. Drawing on SDL and Consumer Culture Theory perspectives we situate the role of fans in value co-creation in Fan Fests and provide implications for management and future research.
Axioms for the set-theoretic hierarchy

The axioms for Zermelo-Fraenkel (ZF) set theory are an appealing but somewhat arbitrary-seeming assortment. A survey of the axioms does not suffice to reveal the source of their attraction. Accordingly, attempts have been made to ground ZF in principles whose appeal can be felt immediately. These attempts can be classified as follows. First, some of them propose to rest the ZF axioms directly on informal doctrine. The others propose to ground the ZF axioms in other formal axioms that can be regarded as more basic. When the latter approach is taken, ZF continues to draw on informal support, but the draft is made at a more basic level. The same research can be classified in another way, according to the informal diagnosis offered for the paradoxes of set theory. In some cases, the diagnosis is that the paradoxical sets (such as the Russell set) fail to exist only because they would have to be too large; a set that would be sufficiently small must always exist. This is the doctrine of limitation of size. In other cases, the diagnosis is that the paradoxical sets fail to exist only because they would have to lie too high in a certain hierarchy of sets; a set that would lie sufficiently low in the hierarchy must always exist. This is the doctrine of the hierarchy. The present paper will investigate the latter doctrine, with the doctrine of size making a brief appearance at the end.