Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparing the toepads of Australian diurnal and nocturnal raptors with nonpredatory taxa: Insights into functional morphology

The ventral structures of the avian digits are the critical interface between a bird and the item within its grasp (e.g., prey, landing substrate, or object), and as such are vital for ensuring the hunting success and survival of predatory birds. Here, we present the first descriptive analysis of the ventral structures of the toes, toepad morphology, and toepad surface area of several diurnal (Accipitriformes and Falconiformes) and nocturnal species (Strigiformes) of Australian raptors. We compare these with nonpredatory taxa (passeriform and psittaciform) to elucidate possible functional explanations for these differences. Although all groups shared the structural characters of joint, phalanx, ungual, and central (tarsal) pad features, the positioning of these structures in relation to the underlying skeletal framework and subsequent gross morphology differed markedly. Toepads overlying the phalangeal joints were much more developed in raptorial species with protrusional toepads only found on goshawks (Accipiter sp.), falcons, and owls. In contrast, the ventral surface of representative passeriform and parrot species showed overall uniformity in contact surface area, with much flatter toepads. There was only a very low phylogenetic signal in the data indicating that phylogenetic relationships did not have a significant effect on toepad surface area. Linear discriminant analysis indicated that functional prey sizes correlated positively with toepad surface areas. Generalized linear modelling showed that there was a positive, significant relationship between body mass and toepad surface area, and prey category significantly affected the toepad surface areas for Digit I and Digit IV. Overall, the ventral surface of the raptorial foot is subject to considerable variation, with active hunters showing the greatest differences in structures, specifically markedly developed toepads to protrusional toepads, potentially as a means to enable more efficient predatory behaviors and facilitate diet preferences for more difficult to catch prey items.
Deposition, dissipation, and minimum effective dosage of the fungicide carbendazim in the pepper-field ecosystem.

BACKGROUND In order to reduce application dosage of carbendazim (CBD), the effects of different droplet sizes and application rate on initial deposition, retention rate, and field control efficacy of CBD in the pepper plant (Capsicum annuum L.) were studied under laboratory and field conditions. RESULTS Based on eight types of nozzles at six concentrations of 646.8, 582.2, 517.5, 414.0, 310.5, and 258.7 g a.i./hm2 , the initial deposition amount of CBD in the pepper plant showed a first increased and then decreased trend with the increasing application dosages. The initial deposition amount of CBD in the pepper leaves and stems was highest when using the nozzle ST110-03 at 200 μm volume median diameter (VMD) and 350 L/hm2 application rate. HPLC-MS/MS analysis revealed that CBD was first converted to 2-aminobenzimidazole, which then transformed into benzimidazole and 2-hydroxybenzimidazole by deamination and hydroxylation, and ultimately mineralized to carbon dioxide and water via the cleavage of the imidazole ring in pepper plant. The dissipation rate of CBD was fruits > roots/stems > leaves > soils. After 7 d of application, the field efficacy of CBD at six concentrations on pepper anthracnose (Colletotrichum spp.) were 94.1%, 91.3%, 82.3%, 76.5%, 47.0%, and 41.2%, respectively. CONCLUSION The results revealed the deposition and dissipation characteristics of CBD, and the minimum effective dosage on pepper anthracnose decreased to 80% of the minimum recommended dose in the open field pepper ecosystem. The study will contribute to the CBD reduction by improving its utilization rate in the pepper-field ecosystem. This article is protected by copyright. All rights reserved.
An Empirical Test of GRUs and Deep Contextualized Word Representations on De-Identification

De-identification aims to remove 18 categories of protected health information from electronic health records. Ideally, de-identification systems should be reliable and generalizable. Previous research has focused on improving performance but has not examined generalizability. This paper investigates both performance and generalizability. To improve current state-of-the-art performance based on long short-term memory (LSTM) units, we introduce a system that uses gated recurrent units (GRUs) and deep contextualized word representations, both of which have never been applied to de-identification. We measure performance and generalizability of each system using the 2014 i2b2/UTHealth and 2016 CEGS N-GRID de-identification datasets. We show that deep contextualized word representations improve state-of-the-art performance, while the benefit of switching LSTM units with GRUs is not significant. The generalizability of de-identification system significantly improved with deep contextualized word representations; in addition, LSTM units-based system is more generalizable than the GRUs-based system.
Evaluation of industrial wastes management practices: Case study of the Savojbolagh industrial zone, Iran

The main objective of this research was to investigate the waste characteristics and management activities in the Savojbolagh industrial zone, Iran, in order to rank the active industries from environmental perspectives using an innovative index. First, the industrial categories with over 50 employees were identified and classified according to their production process. Then, 54 industries were selected and all industrial processes, the types and quantities of products, per capita industrial waste generation, physical analysis and management activities in terms of minimisation, storage, processing, recycling and disposal were evaluated. The required data were obtained through questioners, interviews and field observations. A scoring system was prepared for evaluation of environmental status of waste management practices. Results indicated that the total industrial waste generation rate was 67,258 kg d-1, in which 4528 belonged to hazardous waste. Furthermore, the per capita waste generation rate was 5.51 kg d-1. Plastic, paper and cardboard and metals constituted the most fractions of wastes, respectively. Food and beverage, metallic and chemical/plastic industries were the biggest waste generators. Metallic industries with total score of 502.5 and non-metalic-mineral industries with the total score of 114 were categorised as the best and worst industries in terms of waste management practices.
Early Left Ventricular Involvement Detected by Cardiovascular Magnetic Resonance Feature Tracking in Arrhythmogenic Right Ventricular Cardiomyopathy: The Effects of Left Ventricular Late Gadolinium Enhancement and Right Ventricular Dysfunction

Background Left ventricular (LV) involvement is common in arrhythmogenic right ventricular cardiomyopathy (ARVC). We aim to evaluate LV involvement in ARVC patients by cardiovascular magnetic resonance feature tracking. Methods and Results Sixty‐eight patients with ARVC and 30 controls were prospectively enrolled. ARVC patients were divided into 2 subgroups: the preserved LV ejection fraction (LVEF) group (LVEF ≥55%, n=27) and the reduced LVEF group (LVEF <55%, n=41). Cardiovascular magnetic resonance with late gadolinium enhancement (LGE) and cardiovascular magnetic resonance feature tracking were performed in all subjects. LV global and regional (basal, mid, apical) peak strain (PS) in radial, circumferential and longitudinal directions were assessed, respectively. Right ventricular global PS in three directions were also analyzed. Compared with the controls, LV global and regional PS were all significantly impaired in the reduced LVEF group (all P<0.05). However, only LV global longitudinal PS as well as mid and apical longitudinal PS were impaired in the preserved LVEF group (all P<0.05), and all these parameters were significantly associated with right ventricular global radial PS (r=−0.47, −0.47, and −0.49, respectively, all P<0.001). The reduced LVEF group showed significantly higher prevalence of LGE (95.10% versus 63.00%, P=0.002) than the preserved LVEF group. Moreover, LV radial PS was significantly reduced in LV segments with LGE (33.15±20.42%, n=46) than those without LGE (41.25±15.98%, n=386) in the preserved LVEF group (P=0.016). Conclusions In patients with ARVC, cardiovascular magnetic resonance feature tracking could detect early LV dysfunction, which was associated with LV myocardial LGE and right ventricular dysfunction.
Behavioural impairments in mice of a novel FUS transgenic line recapitulate features of frontotemporal lobar degeneration

Multiple clinical and experimental evidences suggest that amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are members of a disease continuum. Pathological inclusions of fused in sarcoma (FUS) protein have been observed in subsets of patients with these diseases but their anatomical distribution is different for two diseases. These structures are present in motor neurons in ALS cases but in cortical neurons in FTLD cases. Expression of a C‐terminally truncated form of human FUS causes an early onset and progressive motor neuron pathology in transgenic mice but only when these neurons express a certain level of this protein. Severe motor dysfunction and early lethality of mice with expression above this level prevent their use for studies of FTLD‐related pathology caused by expression of this form of FUS. In the present study, we used another line of mice expressing the same protein but not developing any signs of motor system dysfunction due to substantially lower level of transgene expression in motor neurons. In a set of tests 5‐month old mice displayed certain behavioural abnormalities, including increased impulsivity, decreased anxiety and compromised social interaction, which recapitulate behaviour characteristics typically seen in FTLD patients.
Integrated analysis of circular RNA-associated ceRNA network in cervical cancer

Abstract Background: Circular RNAs (circRNAs) have displayed dysregulated expression in several types of cancer. Nevertheless, their function and underlying mechanisms in cervical cancer remains largely unknown. This study aimed to describe the regulatory mechanisms in cervical cancer. Methods: We downloaded the circRNAs expression profiles from Gene Expression Omnibus database, and RNAs expression profiles from The Cancer Genome Atlas database. We established a circRNA-miRNA-mRNA and circRNA-miRNA-hubgene network. The interactions between proteins were analyzed using the STRING database and hubgenes were identified using MCODE plugin. Then, we conducted a circRNA-miRNA-hubgenes regulatory module. Functional and pathway enrichment analyses were conducted using R packages “Clusterprofile”. Results: Six circRNAs, 15 miRNAs, and 158 mRNAs were identified to construct the ceRNA network of cervical cancer. PPI (protein-protein interaction) network and module analysis identified 7 hubgenes. Then, a circRNA-miRNA-hubgene subnetwork was constructed based on the 1 DEcircRNAs, 3 DEmiRNAs, and 3 DEmRNAs. The KEGG pathway analysis indicated DEmRNAs are involved in progesterone-mediated oocyte maturation, cell cycle, and oocyte meiosis. Conclusion: These ceRNAs are critical in the pathogenesis of cervical and may serve as future therapeutic biomarkers.
Advances in science and applications in air pollution monitoring: A case study on oil sands monitoring targeting ecosystem protection

Air Quality Consultant, Danville, CA, USA; Geological Survey of Canada, Natural Resources Canada, Québec, QC, Canada; State Key Laboratory of Loess and Quaternary Geology (SKLLQG), Institute of Earth Environment, Chinese Academy of Sciences, Xi’an, Shaanxi Province, People’s Republic of China; Desert Research Institute, Reno, NV, USA; Canadian Natural Resources Limited, Calgary, Alberta, Canada; Integrated Environmental Analytics & Prediction Branch, Alberta Environment and Parks, Edmonton, Alberta, Canada; BioSphere Solutions, Calgary, Alberta, Canada; Atlantic Forest Research Collaborative, University of New Brunswick, Fredericton, New Brunswick, Canada; Bay Area Air Quality Management District, San Francisco, CA, USA
Configuration of Input Forms in EHR Systems Using Spreadsheets, openEHR Archetypes and Templates

Differences in structure and semantics of data captured using screen forms in different Electronic Health Record (EHR) products and configurations is the root cause of many interoperability problems. We present a workaround enabling reuse of openEHR archetype and template semantics to configure forms in four surveyed, insufficiently standardized, EHR-products used in Sweden (Cerner Melior, Cerner Millenium, Cambio Cosmic and CGM TakeCare). Data from EHRs was then exported and queried using standardized query mechanisms.
Standardizing Key Issues from Hospital Through an Electronic Multi-Professional Discharge Checklist to Ensure Continuity of Care

This article describes development of the multi-professional discharge checklist and its implementation into the nursing documentation system (NDS) as part of the patient's overall care plan. The aim was to harmonize patient's admission and care period documentation and to improve the quality of electronic nursing discharge summaries. The ultimate goal was to ensure continuity of care. The multidisciplinary discharge checklist was developed in two phases to support the discharge of elderly patients (over 65 years). First, the information content of the checklist was defined, and second, it was integrated into the NDS. Focus groups of social and healthcare professionals (n = 82) in specialist health care, primary health care and social services defined the information content and participated in the feedback and checking rounds. The development work should continue. Particular attention should be given to the technical performance of discharge checklists in the NDS.
In-Ear Pulse Rate Measurement: A Valid Alternative to Heart Rate Derived from Electrocardiography?

Heart rate measurement has become one of the most widely used methods of monitoring the intensity of physical activity. The purpose of this study was to assess whether in-ear photoplethysmographic (PPG) pulse rate (PR) measurement devices represent a valid alternative to heart rate derived from electrocardiography (ECG), which is considered a gold standard. Twenty subjects (6 women, 14 men) completed one trial of graded cycling under laboratory conditions. In the trial, PR was recorded by two commercially available in-ear devices, the Dash Pro and the Cosinuss°One. They were compared to HR measured by a Bodyguard2 ECG. Validity of the in-ear PR measurement devices was tested by ANOVA, mean absolute percentage errors (MAPE), intra-class correlation coefficient (ICC), and Bland–Altman plots. Both devices achieved a MAPE ≤5%. Despite excellent to good levels of agreement, Bland–Altman plots showed that both in-ear devices tend to slightly underestimate the ECG’s HR values. It may be concluded that in-ear PPG PR measurement is a promising technique that shows accurate but imprecise results under controlled conditions. However, PPG PR measurement in the ear is sensitive to motion artefacts. Thus, accuracy and precision of the measured PR depend highly on measurement site, stress situation, and exercise.
Impact of Organic Manure on Growth, Nutrient Content and Yield of Chilli Pepper under Various Temperature Environments

Expected climatic changes likely elicit serious challenges for crop production. Therefore, it is indispensable to investigate the response of crop growth parameters and yield under temperature variability environments. The current experiment on chilli pepper growth was conducted in a field, rain-shelter plastic house, and plastic greenhouse, with accumulated temperatures of 2832 °C, 2967 °C, and 3105 °C in 2017; and 2944 °C, 3091 °C, and 3168 °C in 2018 growing seasons. Based on soil analysis, 132.7 kg ha−1 (1× of livestock manure compost as an optimum and 265.4 kg ha−1 (2×) as a double amount of organic matter were applied to each simulated temperature condition. The results showed that organic manure application favorably affects the growth attributes and nutrient uptake of chilli pepper with the highest values found in the plastic greenhouse, followed by the rain-shelter house, over the open field cultivation condition. The highest growth of chilli pepper was at the 2× rate of organic manure application, whereas the highest yield was found at the 1× rate of organic manure application. The application of organic manure at the 1× rate in the greenhouse increased root, shoot, and fruit dry weights of chilli pepper by 21.4%, 52.4%, and 79.7%, respectively, compared to the control values. These results indicate that the rational use of organic amendments might be the best solution for chilli pepper production under variable climate conditions.
Enabling West African Herbal-Based Traditional Medicine Digitizing: The WATRIMed Knowledge Graph

The purpose of this study is to describe the design and development of the first release of the West African Herbal based Traditional Medicine Knowledge Graph (WATRIMed). It is a resource containing Traditional Medicine (TM) related entities and linked with publicly available knowledge bases in order to facilitate bringing West African TM into the digital world. The core model comprises currently 556 concepts including 143 identified West African medicinal plants and 108 recipes used by tradi-practitioners to treat 110 diseases and symptoms which are commonly encountered in this part of the world.
Synthesizing the Practice of SCMC-based Telecollaboration: A Scoping Review

Telecollaboration is a type of online learning arrangement between geographically distant participants for the development of language and intercultural competence. After two decades of research, it is an apt time to engage in a systematic review of previous studies in the form of a scoping review in order to illuminate the pedagogical practices commonly used in telecollaboration. The study synthesized 55 distinct telecollaboration projects that took place in university foreign-language classes and utilized synchronous computer-mediated communication (SCMC) tools to answer (1) What are the typical arrangements of SCMC-based telecollaboration (e.g., participants, project set-ups, and interaction set-ups)? and (2) How have SCMC-based telecollaboration projects changed over the last two decades? We identified six commonly adopted arrangements of SCMC-based telecollaboration. We also found that, while certain pedagogical practices in telecollaboration have matured, the field is undergoing reconceptualization and expansion with the advancement of technology and diversification of participants. We conclude the article with suggestions regarding reporting practices in telecollaboration research, thereby enabling more rigorous synthesis in the future.
Gestational intermittent hypoxia induces endothelial dysfunction, reduces perivascular adiponectin and causes epigenetic changes in adult male offspring

Obstructive sleep apnoea (OSA) is characterized by intermittent hypoxia, which causes oxidative stress and inflammation and increases the risk of cardiovascular disease. OSA during pregnancy causes adverse maternal and fetal outcomes. The effects of pre‐existing OSA in pregnant women on cardiometabolic outcomes in the offspring are unknown. We evaluated basic metabolic parameters, as well as aortic vascular and perivascular adipose tissue (PVAT) function in response to adiponectin, and examined DNA methylation of adiponectin gene promoter in PVAT in 16‐week‐old adult offspring exposed to gestational intermittent hypoxia (GIH). GIH decreased body weights at week 1 in both male and female offspring, and caused subsequent increases in body weight and food consumption in male offspring only. Adult female offspring had normal levels of lipids, glucose and insulin, with no endothelial dysfunction. Adult male offspring exhibited dyslipidaemia, insulin resistance and hyperleptinaemia. Decreased endothelial‐dependent vasodilatation, loss of anti‐contractile activity of PVAT and low circulating PVAT adiponectin levels, as well as increased pro‐inflammatory gene expression and DNA methylation of adiponectin gene promoter, occurred in adult male offspring. Our results suggest that male offspring of women with OSA could be at risk of developing cardiometabolic disease during adulthood.
Acute phase response and inflammation following pulmonary exposure to low doses of zinc oxide nanoparticles in mice

Abstract Inhalation of nanosized zinc oxide (ZnO) induces metal fume fever and systemic acute phase response in humans. Acute phase response activation is a cardiovascular risk factor; we investigated whether pulmonary exposure of mice can be used to assess ZnO-induced acute phase response as well as inflammation and genotoxicity. Uncoated (NM-110) and triethoxycaprylylsilane-coated (NM-111) ZnO nanoparticles were intratracheally instilled once at 0.2, 0.7 or 2 µg/mouse (11, 33 and 100 µg/kg body weight). Serum amyloid A3 mRNA level in lung tissue, bronchoalveolar lavage (BAL) fluid cellularity, and levels of DNA strand breaks in BAL fluid cells, lung and liver tissue were assessed 1, 3 and 28 days post-exposure. Global transcription patterns were assessed in lung tissue using microarrays. The acute-phase response serum amyloid A3 mRNA levels were increased on day 1; for uncoated ZnO nanoparticles at the highest dose and for coated ZnO nanoparticles at medium and highest dose. Neutrophils were increased in BAL fluid only after exposure to coated ZnO nanoparticles. Genotoxicity was observed only in single dose groups, with no dose-response relationship. Most changes in global transcriptional response were observed after exposure to uncoated ZnO nanoparticles and involved cell cycle G2 to M phase DNA damage checkpoint regulation. Although, uncoated and coated ZnO nanoparticles qualitatively exerted similar effects, observed differences are likely explained by differences in solubility kinetics. The finding of serum amyloid A3 induction at low exposure suggests that mouse models can be used to assess the nanoparticle-mediated induction of acute phase responses in humans.
Organizational Culture and Job Demands and Resources: Their Impact on Employees’ Wellbeing in a Multivariate Multilevel Model

(1) The present study aims to explore the impact of job demands and resources (JDR), personal resources, and the organizational culture on workers’ wellbeing and health. (2) A cross-sectional survey of Spanish workers in small and medium-sized enterprises (SMEs) was conducted with a sample of 1599 workers from 154 SMEs. A multivariate multilevel analysis was performed to analyze the different relationships. (3) In light of the results obtained, we observed that job demands were negatively associated with workers’ health, while job resources were positively correlated to workers’ health and wellbeing. Secondly, the different types of identification at work are positively related to job satisfaction and organizational citizenship behaviors (OCBs), but the intensity of this association differs with the form of identification. Finally, at the organization level, the dimensions of organizational culture are related differently to employees’ job satisfaction, OCBs, and health; (4) these results confirm the role of organizational culture and its association with desirable outcomes, allowing us to expand the JDR model.