Miracle-dz/UniFAR-FTUs huggingface dataset:
Selected Topics: Cardiology Commentary UPWARDLY CONCAVE ST SEGMENT MORPHOLOGY IS COMMON IN ACUTE LEFT ANTERIOR DESCENDING CORONARY OCCLUSION

e Abstract—ST elevation (STE) in anterior precordial leads, in association with upwardly convex morphology (M) or straightM, is associated with anterior acute myocardial infarction (aAMI). Upwardly concaveM is characteristic of pseudoinfarction patterns such as early repolarization. A retrospective review was done of diagnostic electrocardiograms (EKG) of consecutive patients presenting to our Emergency Department (ED) who underwent emergent primary percutaneous intervention (PCI) and had proven left anterior descending (LAD) occlusion. If all leads from V2–V6 were upwardly concave, the EKG was classified as concaveM. If one lead was convex, the EKG had convexM. If no leads were convex and at least one was straight, it had straightM. Non-concaveM was defined as either convexM or straightM. Borderline STE was defined if the EKG did not have 2 consecutive leads with > 2 mm of STE. “Subtle,” as opposed to “diagnostic,” morphology was defined as concaveM without terminal QRS distortion. Data were analyzed with descriptive statistics. There were 37 patients identified who met the inclusion criteria and whose records were available for review. ConcaveM was found in 16 of 37 (43%), 4 with terminal QRS distortion. Measurements resulted in a classification of borderline STE in 15 of 37 (41%) (9 of whom had subtle morphology) for Rater 1 and 12 of 37 (32%) (7 of whom had subtle morphology) for Rater 2, while 19% to 24% had both “subtle” morphology and borderline ST elevation. ConcaveM, as compared with convexM or terminal QRS distortion, was associated with a shorter duration of symptoms (p < 0.05). It is concluded that concave morphology cannot be used to exclude STEMI with LAD occlusion. Many patients with LAD occlusion have borderline ST elevation with subtle morphology. Concave morphology is associated with a shorter duration of
Emerging professional teacher identity of early childhood development / foundation phase pre-service teachers : an interplay of dispositions.

iv Table of contents . v List of figures and tables. xiii List of appendices . xiv Acronyms.xv CHAPTER 1: PROFESSIONAL TEACHER IDENTITY AND TEACHER QUALITY IN ECD/FP 1.
The Life Cycle Assessment of an Energy‐Positive Peri‐Urban Residence in a Tropical Regime

Urban settlements are home to the greatest levels of greenhouse gas emissions and energy consumption globally, with unprecedented rates of urban expansion occurring today. With the majority of global urbanization occurring along the periphery of urban areas in developing countries, investigation of “green” building practices designed specifically for “peri‐urban” regions is critical for a low‐emitting future society. This study assesses a state‐of‐the‐art residence designed for a middle‐class family of four residing in the peri‐urban region of Bangkok, Thailand. The residence employs both demand‐side management strategies and low‐emitting energy supply technology to achieve energy‐positive status. To elucidate the influence that key design decisions have on the life cycle sustainability of the home, several variants of the residence are modeled. A process‐based life cycle assessment consistent with the International Organization for Standardization (ISO) 14044:2006 standard and following ReCiPe Midpoint life cycle impact assessment methodology is used to quantify the life cycle impacts per square meter of conditioned residence floor area for climate change (582 kilograms [kg] carbon dioxide equivalent), terrestrial acidification (4.01 kg sulfur dioxide equivalent), freshwater eutrophication (30.4 grams phosphorous equivalent), fossil depletion (362 kg iron equivalent), and metal depletion (186 kg oil equivalent) impacts. We model multiple scenarios in which varying proportions of Bangkok's peri‐urban detached housing demand are fulfilled by the energy‐positive residence variants. Under the best‐case replacement scenario (i.e., 100% replacement of future peri‐urban detached housing), significant reductions are achieved across the life cycle climate change (80%), terrestrial acidification (82%), and fossil depletion (81%) impact categories for the steel‐framed, energy‐positive residence.
Islamic Credit Card Adoption Understanding: When Innovation Diffusion Theory Meets Satisfaction and Social Influence

ABSTRACT Understanding the main determinants of Islamic credit card (ICC) adoption is important for banks and users. Grounded in Innovation Diffusion Theory, Theory of Reasoned Action, satisfaction, and social influence concepts, this study purposes and empirically tests an integrated model to explore which factors influence acceptance and use of ICC. To test the conceptual model, the data was collected from 967 bank customers and Partial Least Squares (PLS) technique was used to test the forecasting model. Results suggest that intentions to use and attitude toward use of ICC are mostly determined by relative advantage, compatibility, social influence, and satisfaction.
Functional Outcomes and Return to Sports After Acute Repair, Chronic Repair, and Allograft Reconstruction for Proximal Hamstring Ruptures

Background: There are limited data regarding outcomes and return to sports after surgery for acute versus chronic proximal hamstring ruptures. Hypothesis: Surgery for chronic proximal hamstring ruptures leads to improved outcomes and return to sports but at a lower level than with acute repair. Proximal hamstring reconstruction with an Achilles allograft for chronic ruptures is successful when direct repair is not possible. Study Design: Cohort study; Level of evidence, 3. Methods: Between 2002 and 2012, a total of 72 patients with a traumatic proximal hamstring rupture (51 acute, 21 chronic) underwent either direct tendon repair with suture anchors (n = 58) or Achilles allograft tendon reconstruction (n = 14). Results from the Single Assessment Numeric Evaluation (SANE) for activities of daily living (ADL) and sports-related activities, Short Form–12 (SF-12), visual analog scale (VAS), and a patient satisfaction questionnaire were obtained. Results: The mean time to surgery in the chronic group was 441.4 days versus 17.8 days in the acute group. At a mean follow-up of 45 months, patients with chronic tears had inferior sports activity scores (70.2% vs 80.3%, respectively; P = .026) and a trend for decreased ADL scores (86.5% vs 93.3%, respectively; P = .085) compared with those with acute tears. Patients with chronic tears, however, reported significant improvements postoperatively for both sports activity scores (30.3% to 70.2%; P < .01) and ADL scores (56.1% to 86.5%; P < .01). Greater than 5 to 6 cm of retraction in the chronic group was predictive of the need for allograft reconstruction (P = .015) and resulted in ADL and sports activity scores equal to those of chronic repair (P = .507 and P = .904, respectively). There were no significant differences between groups in SF-12, VAS, or patient satisfaction outcomes (mean, 85.2% satisfaction overall). Conclusion: Acute repair was superior to chronic surgery with regard to return to sports. Acute and chronic proximal hamstring repair and allograft reconstruction had favorable results for ADL. For low-demand patients or those with medical comorbidities, delayed repair or reconstruction might be considered with an expected 87% return to normal ADL. For patients who desire to return to sports, acute repair is recommended.
Antagonistic coevolution across productivity gradients: an experimental test of the effects of dispersal

Coevolution commonly occurs in spatially heterogeneous environments, resulting in variable selection pressures acting on coevolving species. Dispersal across such environments is predicted to have a major impact on local coevolutionary dynamics. Here, we address how co‐dispersal of coevolving populations of host and parasite across an environmental productivity gradient affected coevolution in experimental populations of bacteria and their parasitic viruses (phages). The rate of coevolution between bacteria and phages was greater in high‐productivity environments. High‐productivity immigrants (∼2% of the recipient population) caused coevolutionary dynamics (rates of coevolution and degree of generalist evolution) in low‐productivity environments to be largely indistinguishable from high‐productivity environments, whereas immigration from low‐productivity environments (∼0.5% of the population) had no discernable impact. These results could not be explained by demography alone, but rather high‐productivity immigrants had a selective advantage in low‐productivity environments, but not vice versa. Coevolutionary interactions in high‐productivity environments are therefore likely to have a disproportionate impact on coevolution across the landscape as a whole.
The Political Economy of Unfinished Development Projects: Corruption, Clientelism, or Collective Choice?

Development projects like schools and latrines are popular with politicians and voters alike, yet many developing countries are littered with half-finished projects that were abandoned mid-construction. Using an original database of over 14,000 small development projects in Ghana, I estimate that one-third of projects that start are never completed, consuming nearly one-fifth of all local government investment. I develop a theory of project noncompletion as the outcome of a dynamically inconsistent collective choice process among political actors facing commitment problems in contexts of limited resources. I find evidence consistent with key predictions of this theory, but inconsistent with alternative explanations based on corruption or clientelism. I show that fiscal institutions can increase completion rates by mitigating the operational consequences of these collective choice failures. These findings have theoretical and methodological implications for distributive politics, the design of intergovernmental transfers and aid, and the development of state capacity.
Timing of the occurrence of pulmonary embolism in trauma patients.

OBJECTIVE To determine how soon after trauma pulmonary embolism (PE) occurs and if there is an association between the duration of this interval and mortality. DESIGN Retrospective case series. PATIENTS All patients admitted to our trauma service with established PE based on high probability findings on ventilation perfusion scan, positive results on a pulmonary arteriogram, or autopsy from July 1, 1990, to September 30, 1995. MAIN OUTCOME MEASURE Time interval between injury and PE. SETTING Level I university trauma center. RESULTS Of 18,255 trauma patients identified, 63 met our criteria for PE (30 using a pulmonary arteriogram; 26, a ventilation perfusion scan; and 7, autopsy). Four patients (6%) had a documented PE on day 1 following injury. Mortality was not correlated with the interval between injury and PE. Of the 63 patients, 58 (92%) had 1 or more established risk factors for thromboembolism. The ratio of PaO2 to fraction of inspired oxygen was the only factor predictive of mortality (P = .02, logistic regression analysis). CONCLUSIONS Pulmonary embolism occurs in the immediate period following injury. Aggressive workup in patients with signs consistent with PE should be instituted promptly. Trauma patients who have at least 1 risk factor for thromboembolism should receive prophylaxis as soon after injury as possible.
Macroeconomic shocks and stock market returns: the case of Korea

ABSTRACT This study examines the effects of macroeconomic shocks on key macro variables, including stock market returns in Korea, using the structural vector autoregression (SVAR) model. We suggest a three-variable SVAR model incorporating inflation, output growth and stock returns. We adopt a nonzero z-ratio restriction for the long-run identifying assumption to allow for economically meaningful relationships among variables. While our results support the negative (positive) relation of demand (supply) shocks to stock returns, we also find that demand shocks influence stock market variance more significantly than supply shocks do. The sub-period analysis finds that global market fluctuations during the global financial crisis have relatively little effect on Korean stock market performance. We also examine a generalized five-variable model that includes the foreign exchange rate and interest rate, confirming the results from the three-variable case.
Post-arc current of vacuum DC interruption

Post-arc current significantly influences the interrupting process of breakers, which can reflect the appearance of the arc before current zero and the residual metal vapors in electrode distance after current zero. In order to investigate the characteristics of post-arc current in DC interruption, a high speed hybrid actuator was designed, and forced current zero method was used to carry out the DC interrupting experiments in the synthetic test circuit. Also, the equipment for the measurement of post-arc current was established to study the factors influencing on the post-arc current, including the rated breaking current and electrode distance. The experimental results indicated that post-arc current presented the instability in a certain range, due to the different contact structures, arcing positions and so on. To some extent, post-arc current also reflects the sheath growth process after the current zero. Furthermore, the amplitude of post-arc current changes with the variation of electrode distances. And for the same distances, post-arc current keeps stable in a certain range. While the rated breaking current is lower than 800A, post-arc current increases with a high growth rate. And it is under a low growth rate and no sharply when the rated breaking current varies within 800A to 2000A. For the same electrode distances, post-arc current presents a significant increase with the increase of commutation frequency. It is for the reason that more residual metal vapors exist in the electrode distance after current zero for higher commutation frequency, which goes against for the DC interruption.
Eculizumab Therapy for Chronic Antibody‐Mediated Injury in Kidney Transplant Recipients: A Pilot Randomized Controlled Trial

We hypothesized that de novo donor‐specific antibody (DSA) causes complement‐dependent endothelial cell injury in kidney transplants, as assessed by expression of endothelial cell–associated transcripts (ENDATs), that may be attenuated through complement inhibition. In total, 15 participants (five control, 10 treatment) with DSA and deteriorating renal function were enrolled. The treatment group received 6 mo of eculizumab followed by 6 mo of observation, whereas controls were observed. The primary end point was percentage change in estimated GFR (eGFR) trajectory over the treatment period. The treatment group had an improved eGFR trajectory versus control, based on our predetermined two‐sided 0.10 significance level (p = 0.09). Within‐subject analysis of treated participants at 6‐mo intervals did not show significant change (p = 0.60). Modeling C1q status showed that C1q‐positive patients had significantly higher mean eGFR than patients with negative C1q (p = 0.04). Biopsies revealed elevated renal ENDATs in most participants, but ENDATs were not reduced with complement inhibition. Our data suggest that eculizumab treatment may stabilize kidney function in patients with chronic persistent DSA based on our pilot a priori significance threshold. ENDAT expression predicative of acute humoral injury is not reduced with complement inhibition in this chronic setting. Further studies will be necessary to determine which patients may benefit from eculizumab.
Measurement of fractional whole-body gluconeogenesis in humans from blood samples using 2H nuclear magnetic resonance spectroscopy.

Several problems limit quantification of gluconeogenesis. We applied in vitro 2H-nuclear magnetic resonance (NMR) spectroscopy to simultaneously measure 2H in all glucose carbons for direct assessment of gluconeogenesis. This method was compared with 2H measurement in carbons 5 and 2 using gas chromatography-mass spectrometry (hexamethylenetetramine [HMT]) and with in vivo 13C magnetic resonance spectroscopy (MRS). After 14 h of fasting, and following 2H2O ingestion, blood was obtained from nine healthy and seven type 2 diabetic subjects. Glucose was purified, acetylated, and analyzed for 2H in carbons 1-6 with 2H-NMR. Using 5:2 ratios, gluconeogenesis increased (P < 0.05) over time and mean gluconeogenesis was lower in control subjects than in type 2 diabetic patients (63 +/- 3 vs. 75 +/- 2%, P < 0.01). 13C-MRS revealed higher hepatic glycogenolysis in control subjects (3.9 +/- 0.4 vs. 2.3 +/- 0.2 micromol.kg(-1). min(-1)) yielding mean contribution of gluconeogenesis of 65 +/- 3 and 77 +/- 2% (P < 0.005). Measurement of gluconeogenesis by 2H-NMR correlated linearly with 13C-MRS (r = 0.758, P = 0.0007) and HMT (r = 0.759, P = 0.0007). In an additional protocol, 2H enrichments demonstrated a fast decline of gluconeogenesis from approximately 100 to approximately 68% (P < 0.02) within 4 h of galactose infusion after 40-44 h of fasting. Thus, in vitro 2H-NMR offers an alternative approach to determine fractional gluconeogenesis in good agreement with standard methods and allows monitoring of rapid metabolic alterations.
Regeneration of Osteonecrosis of Canine Scapho-lunate Using Bone Marrow Stromal Cells: Possible Therapeutic Approach for Kienböck Disease

We evaluated the ability of canine bone marrow stromal cells (cBMSCs) to regenerate bone in a cavity of the scapholunate created by curretage and freeze–thawing with liquid nitrogen (LN). Autologous BMSCs were harvested from the iliac crest and expanded in vitro. Their potential to differentiate into osteo-, chondro-, and adipogenic lineages was confirmed using a standard differentiation induction assay. LN-treated scapholunates showed no regeneration of bone tissue when the cavity was left alone, demonstrating severe collapse and deformity as observed in human Kienböck disease. A combination of β-tri-calcium phosphate and a vascularized bone graft with autologous fibroblasts failed to regenerate bone in the LN-treated cavity. When the same procedure was performed using BMSCs, however, LN-treated scapholunates showed no collapse and deformity, and the cavity was completely filled with normal cancerous bone within 4 weeks. These results suggested the potential of using BMSCs to treat Kienböck disease.
Ingress Filtering for Multihomed Networks

BCP 38, RFC 2827, is designed to limit the impact of distributed denial of service attacks, by denying traffic with spoofed addresses access to the network, and to help ensure that traffic is traceable to its correct source network. As a side effect of protecting the Internet against such attacks, the network implementing the solution also protects itself from this and other attacks, such as spoofed management access to networking equipment. There are cases when this may create problems, e.g., with multihoming. This document describes the current ingress filtering operational mechanisms, examines generic issues related to ingress filtering, and delves into the effects on multihoming in particular. This memo updates RFC 2827.
Early cleavages influence the molecular and the metabolic pattern of individually cultured bovine blastocysts

Embryo morphokinetics suggests that the timing of the first embryonic cell divisions may predict the developmental potential of an embryo; however, correlations between embryonic morphokinetics and physiology are not clear. Here, we used RNA sequencing to determine the gene expression profile of in vitro‐produced early‐ and late‐dividing bovine embryos and their respective blastocysts, and compared these profiles to in vivo‐produced blastocysts to identify differentially expressed genes (DEGs). Principal component analysis revealed that fast‐ and slow‐dividing embryos possess similar transcript abundance over the first cleavages. By the blastocyst stage, however, more DEGs were observed between the fast‐ and slow‐dividing embryo groups, whereas blastocysts from the slow‐dividing group were more similar to in vivo‐produced blastocysts. Gene ontology enrichment analysis showed that the slow‐dividing and in vivo‐produced blastocysts shared biological processes related to groups of up‐ or down‐regulated genes when compared to the fast‐dividing blastocysts. Based on these DEG results, we characterized the relationship between developmental kinetics and energy metabolism of in vitro‐produced bovine embryos. Embryos from fast‐ and slow‐dividing groups exhibited different pyruvate and lactate metabolism at 22 hr post‐in vitro culture (hpc), glucose consumption at 96 hpc, and glutamate metabolism at 168 hpc. Glycogen storage was similar between cleavage‐stage and morulae groups, but was higher in the blastocysts of the slow‐dividing group. On the other hand, blastocysts of the fast‐dividing group had a higher concentration of lipids. Taken together, these data identify transcriptomic and metabolic differences between embryos with different morphokinetics, suggesting that sorting embryos based on cleavage speed may select for different metabolic patterns. Mol. Reprod. Dev. 83: 324–336, 2016. © 2016 Wiley Periodicals, Inc.
Proceedings of the International Scientific Conference of Business Economics Management and Marketing (ISCOBEMM) 2016

These proceedings present the latest scientific findings in the mentioned area, which makes me believe that you will find reading it helpful and inspirational for your further scientific and research activities. Also, I would like to use this opportunity to invite you to attend another (the second) year of this conference, which is to be held next year
Functional neuroanatomy of sustained attention in schizophrenia: Contribution of parietal cortices

Deficits in sustained attention have been frequently described in schizophrenia. The neuroanatomical basis reported previously have included altered levels of activation in cingulate and prefrontal cortex, but the contribution of further regions remains unclear. We explored the full neuroanatomy underlying the sustained attentional deficits observed in naïve schizophrenics compared with controls. Participants included 10 controls and 11 patients. The experimental design included rest, auditory stimulation using clicks, and two counting tasks. Subjects were instructed to mentally count the clicks, and then to count forward at the same frequency they heard previously when listening to the clicks. Relative cerebral blood flow (relCBF) was measured by means of PET 15O‐water. Differences were observed between both groups at superior temporal cortex, superior parietal gyrus, and cerebellum during tasks requiring listening. During all counting conditions, additionally to supplementary motor area (SMA), dorsolateral prefrontal cortex (DLPCF), precentral gyrus, cingulate, cerebellum, and inferior parietal (IP) gyrus, patients engaged other frontal structures including inferior, medial, and superior frontal areas. When counting with no auditory stimulation (C; requires components of working memory and time estimation), significant differences were observed in the level of activation of frontal and IP regions. Our naïve patients presented abnormal activation of auditory associative pathways. They failed to activate prefrontal and parietal regions at a similar level during tasks requiring increased cognitive effort, and they required a higher activation of inferior frontal regions to properly respond to cognitive demands. Hum. Brain Mapping 17:116–130, 2002. © 2002 Wiley‐Liss, Inc.