Miracle-dz/UniFAR-FTUs huggingface dataset:
EFFECT OF INTRAVENOUS FLUID SUPPLEMENTATION ON SERUM BILIRUBIN LEVEL IN JAUNDICED HEALTHY NEONATES DURING CONVENTIONAL PHOTOTHERAPY

Background: Adequate hydration and good urine output improve the efficacy of phototherapy. The aim of this study was to evaluate the effect of intravenous fluid supplementation on decrease of serum bilirubin levels in jaundiced healthy term infants during conventional phototherapy. Methods: Sixty healthy breast-fed neonates with non-hemolytic hyperbilirubinemia were assigned randomly to receive either breast milk exclusively (non-supplemented group; n=30) or intravenous fluid in addition to breast milk (supplemented group; n=30) during conventional phototherapy. Results: The mean total serum bilirubin (TSB) levels at the time of enrollment and within 84 hours after phototherapy were not statistically different between two groups. Similarly, the mean rate of decrease in TSB levels during the first 12 h of phototherapy were 0.13Â±0.06 and 0.10 Â± 0.1 mg/dL/h in supplemented and non supplemented groups , respectively (P=0.13). Duration of phototherapy required in supplemented and non-supplemented groups was 58 Â± 13.02 and 63.20 Â± 13.71 hours, respectively (P=0.13). Conclusion: These data show that administration of extra intravenous fluid in jaundiced healthy, term, breastfed neonates have no beneficial effect on the rate of serum bilirubin reduction during conventional phototherapy. Keywords: Hyperbilirubinemia, Phototherapy, Neonates, Fluid Supplementation, Dehydration.
Meta-Analysis of the Use of 8-OHdG in Saliva as a Marker of Periodontal Disease

The objective was to collect the available evidence on oxidative stress marker measurements in periodontal patients, focusing specifically on 8-hydroxy-2′-deoxyguanosine (8-OHdG) as a salivary marker of periodontal disease, and to perform meta-analyses to calculate differences in concentration compared to healthy persons. A systematic search in PubMed, Cochrane Library, Embase, and Scopus identified 81 articles. Of these, 38 were duplicates. After reading the abstracts of the remaining 43, 42 were selected for full-text assessment. Finally, 17 articles were included in the qualitative synthesis. Those excluded were of low quality, did not answer the research question, or did not meet the inclusion and exclusion criteria. Of the 17 in the qualitative synthesis, 9 were included in the meta-analysis. The 9 studies in the meta-analysis were combined in a random effects model. Their heterogeneity was high (Q = 3982.02, p < 0.001, I2 = 99.8%). The difference in mean 8-OHdG concentration in saliva between periodontal and healthy subjects was estimated at 2.11 ng/ml (95% CI 1.23–2.98). The different saliva collection methods (stimulated/unstimulated) did not explain the heterogeneity. The 8-OHdG levels in saliva of periodontal patients were almost double to those of healthy patients: 8-OHdG is clearly a powerful periodontal disease marker.
Lung Involvements in Rheumatic Diseases: Update on the Epidemiology, Pathogenesis, Clinical Features, and Treatment

Lung illness encountered in patients with rheumatic diseases bears clinical significance in terms of increased morbidity and mortality as well as potential challenges placed on patient care. Although our understanding of natural history of this important illness is still limited, epidemiologic knowledge has been accumulated during the past decade to provide useful information on the risk factors and prognosis of lung involvements in rheumatic diseases. Moreover, the pathogenesis particularly in the context of genetics has been greatly updated for both the underlying rheumatic disease and associated lung involvement. This review will focus on the current update on the epidemiologic and genetics features and treatment options of the lung involvements associated with four major rheumatic diseases (rheumatoid arthritis, systemic sclerosis, myositis, and systemic lupus erythematosus), with more attention to a specific form of involvement or interstitial lung disease.
How Gender and Skin Tone Modifiers Affect Emoji Semantics in Twitter

In this paper we analyze the use of emojis in social media with respect to gender and skin tone. By gathering a dataset of over twenty two million tweets from United States some findings are clearly highlighted after performing a simple frequency-based analysis. Moreover, we carry out a semantic analysis on the usage of emojis and their modifiers (e.g. gender and skin tone) by embedding all words, emojis and modifiers into the same vector space. Our analyses reveal that some stereotypes related to the skin color and gender seem to be reflected on the use of these modifiers. For example, emojis representing hand gestures are more widely utilized with lighter skin tones, and the usage across skin tones differs significantly. At the same time, the vector corresponding to the male modifier tends to be semantically close to emojis related to business or technology, whereas their female counterparts appear closer to emojis about love or makeup.
Moral Cognition and Multiple Sclerosis: A Neuropsychological Study

OBJECTIVES Recent literature proved that social cognition impairments may characterize the neuropsychological profile of Multiple Sclerosis (MS) patients. However, little is still known about moral cognition in MS. In this study, we evaluated non-social, social, and moral cognitive performances in 45 relapsing-remitting MS patients. METHODS Patients underwent the Brief International Cognitive Assessment for Multiple Sclerosis battery, the Cognitive Estimation and Stroop tasks, the Ekman-60 Faces test, the Reading the Mind in the Eye and Story-based Empathy task. Additionally, a task of moral dilemmas including both "instrumental" and "incidental" conditions was administered to patients. Forty-five age-, gender- and education-matched healthy control subjects (HC) were enrolled for comparisons. RESULTS The majority of patients (i.e., 77.6%) showed deficits at non-social tasks, particularly in the executive domains. A subset of MS sample (i.e., 24%) presented with emotion recognition and socio-affective processing impairments. Overall, MS patients showed comparable levels of moral judgment with respect to HC. The rate of yes/no response in resolution of moral dilemmas and scores of attribution of emotional valence were comparable between groups. Nevertheless, lower moral permissibility and emotional arousal, particularly for the instrumental dilemmas, characterized the MS profile. Significant correlations between the attribution of emotional valence to moral actions and mentalizing scores emerged. CONCLUSIONS Our findings expand current literature on MS supporting not only deficits in executive and socio-emotional domains but also low levels of permissibility of immoral actions and emotional detachment in the moral judgment process.
Outcomes of cochlear implantation in children with and without inner ear malformations

Objective: To evaluate the auditory functions and progress of speech development in children with and without cochlear anomalies who underwent cochlear implantation due to prelingual profound sensorineural hearing loss (SNHL). Methods: This study was conducted at Gaziantep University Faculty of Medicine Ear-Nose-Throat Department, between October 2006 and December 2007. A total of 69 children (aged 6 to 24 months) diagnosed with profound SNHL were included. Patients were divided into two groups with respect to the presence of inner ear anomalies: Group-1 consisted of 41 children without inner ear anomaly, whereas Group-2 was composed of 28 patients with inner ear anomalies. The auditory performance was assessed using Listening Progress Profile Test (LPPT) and Monosyllabic Trochee Polysyllabic Test (MTP), the subsections of Evaluation of Auditory Responses to Speech (EARS) test battery. Results: Preoperative LPPT scores were 5 (12%) in both groups. Mean LPPT values after fitting in Group-1 and Group-2 on 1st, 3rd and 6th months were 18.5 (44.1%) and 19 (45.6%); 27 (64.2%) and 28 (67.3%); 31 (75%) and 34 (83%), respectively. Postoperatively, MTP scores in Group-1 and Group-2 were 7.5 (62%) and 7.7 (64%) for 3-words set; 10.4 (58%) and 10.6 (59%) for 6-words set; 14.3 (60%) and 14 (59%) for 12-words set, respectively. The rate of stimulation for electrodes was 1345 q/u (quick/unit) in Group-1 and 1310 q/u in Group-2. No statistically significant difference was detected between groups for variables under investigation. Conclusion: Cochlear implantation is an effective treatment in children with prelingual profound SNHL. Auditory performance and advancement of speech are similar for children with and without inner ear anomalies.
The influence of class attendance on the throughput rates of students at a FET college in South Africa

Student engagement with academics in a classroom environment is one of the oldest and well-known pedagogical strategies while having quality teachers in the classroom is but one indicator of possible student success. In Further Education and Training colleges in South Africa, an 80% classroom attendance is usually required for students to qualify to write their final national examination at the end of the term. The main purpose of this paper is to assess the influence of classroom attendance on the throughput rates of students in a National Certificate offered at a Further Education and Training college in South Africa. The research, on which this study is based, incorporates an ex-post facto study involving a non-experimental correlation design using quantitative data. Results indicate a significant attrition rate of 72%. Senior students in Level 4 seemed to attend more class (average attendance is 55% with 63% passing) as compared to first-year engineering students in Level 2 (average attendance is 48% with 44% passing). Results further show that the throughput rates for Mathematics never exceeded 11%, while students performed very well in Workshop Practice and Electrical Workmanship (peak throughput rate of 100% for Level 3). A key recommendation is to alert management of the non-compliance with the 80% classroom attendance policy, which needs to be revised or re-enforced, so that awareness, transparency and accountability may be promoted.
The Efficacy and Safety of Prophylactic Fluconazole Prevent Invasive Fungal Infection in Preterm Very Low Birth Weight Infants : An Update Meta-analysis

*Corresponding author: Xiao X, Department of Neonatology, the Sixth Affiliated Hospital of Sun Yat-sen University, 26 Yuancun Erheng Road, Guangzhou, Guangdong 510655, People’s Republic of China, Fax: +8620-38777850, Tel: +8613431088188, E-mail: txiaoxin1049@163.com Lin H-C, Division of Neonatology, China Medical University Hospital, No.2 Yuh Der Road, Taichung, 404, Taiwan, Fax: +886-4-22032798, Tel: 0932563999, E-mail: d0373.cmuh@gmail.com
ffects of waterborne silver in a marine teleost , the gulf toadfish ( Opsanus beta ) : ffects of feeding and chronic exposure on bioaccumulation nd physiological responses

Marine teleosts drink seawater, and the digestive tract is a key organ of osmoregulation. The gastrointestinal tract therefore offers a second site for the potential uptake and toxicity of waterborne metals, but how these processes might interact with the digestive functions of the tract has not been investigated previously. We therefore compared the responses of adult gulf toadfish (Opsanus beta, collected from the wild) to a chronic 22 d exposure to waterborne Ag (nominally 200 g L−1 = 1.85 mol L−1), in the presence or absence of daily satiation feeding (shrimp). Ag exposure did not affect voluntary feeding rate. Feeding reduced the net whole body accumulation of Ag by >50%, with reductions in liver concentrations (high) and white muscle concentrations (relatively low) playing the largest quantitative roles. Feeding also protected against Ag buildup in the esophagus-stomach and kidney, and increased biliary and urinary Ag concentrations. The gill was the only tissue to show the opposite response. Although terminal plasma Na+, Cl−, and Mg2+ concentrations were unaffected, there were complex interactive effects on osmoregulatory functions of the gastro-intestinal tract, including drinking rate, gut fluid volumes, and intestinal base secretion rates. At the end of the exposure, the plasma clearance kinetics of an arterially injected tracer dose of 110mAg were faster in toadfish that had been chronically exposed to waterborne Ag, and 110mAg accumulation in their red blood cells was reduced. After 32 h, higher amounts of 110mAg were found in bile and urine, but lower amounts in the intestine of the Ag-exposed toadfish; there were no other differences in tissue-specific distribution. The results suggest that feeding reduces waterborne Ag uptake through the digestive tract and alters physiological responses, while chronic exposure enhances regulatory functions. ns o The time-dependent actio
Automatic knee cartilage segmentation using fully volumetric convolutional neural networks for evaluation of osteoarthritis

Automated Cartilage segmentation is essential for improving the performance of advanced Knee Osteoarthritis (OA) assessment due to its convoluted 3D structure. In this paper, we have developed a knee cartilage segmentation algorithm from a high resolution MR volume using a novel 3D-fully Convolutional Neural Network (CNN), called ‘μ-Net’ coupled with a multi-class loss function. This is, to our knowledge, the first automatic cartilage segmentation method using 3D CNNs. The proposed algorithm performed better than the state-of-the-art algorithm in the MICCAI SKI 10 public challenge. We have further applied our proposed algorithm on another similar MR contrast (DESS) provided by Osteoarthritis Initiative (OAI) for OA assessment and have presented improved segmentation accuracies. Initial qualitative assessment of segmentation results visually depicts cartilage loss in longitudinal knee MR data.
On Laterally Perturbed Human Stance: Experiment, Model, and Control

Understanding human balance is a key issue in many research areas. One goal is to suggest analytical models for the human balance. Specifically, we are interested in the stability of a subject when a lateral perturbation is being applied. Therefore, we conducted an experiment, laterally perturbing five subjects on a mobile platform. We observed that the recorded motion is divided into two parts. The legs act together as a first, the head-arms-trunk segment as a second rigid body with pelvis, and the ankle as hinge joints. Hence, we suggest using a planar double-inverted pendulum model for the analysis. We try to reproduce the human reaction utilizing torque control, applied at the ankle and pelvis. The fitting was realized by least square and nonlinear unconstrained optimization on training sets. Our model is not only able to fit to the human reaction, but also to predict it on test sets. We were able to extract and review key features of balance, like torque coupling and delays as outcomes of the aforementioned optimization process. Furthermore, the delays are well within the ranges typically for such compensatory motions, composed of reflex and higher level motor control.
TCS Research at SemEval-2018 Task 1: Learning Robust Representations using Multi-Attention Architecture

This paper presents system description of our submission to the SemEval-2018 task-1: Affect in tweets for the English language. We combine three different features generated using deep learning models and traditional methods in support vector machines to create a unified ensemble system. A robust representation of a tweet is learned using a multi-attention based architecture which uses a mixture of different pre-trained embeddings. In addition to this analysis of different features is also presented. Our system ranked 2nd, 5th, and 7th in different subtasks among 75 teams.
Comparison of the Bony Changes of TMJ in Patients With and Without TMD Complaints Using CBCT

Statement of the Problem: Temporomandibular joint disorders (TMD) may show a poor correlation between their clinical findings and radiological characteristics. Purpose: The aim of this study was to assess the osseous alterations of temporomandibular joint (TMJ) in symptomatic and asymptomatic subjects by employing cone beam computed tomography (CBCT) images. Materials and Method: In this study, CBCT images of 120 temporomandibular joints in 30 patients with TMJ disorder and 30 age- and sex-matched individuals without TMJ complaints were evaluated. Osteoarticular derangements of the joint were assessed by two experienced examiners. Data was statistically analyzed with SPSS software using chi-square test (p <0.05). Results: Out of 120 CBCT images (60 in each group), at least one osseous change was observed in 90% and 86.7% joints in symptomatic and asymptomatic subjects, respectively. There were no significant differences between symptomatic and asymptomatic subjects regarding frequency of osteoarticular changes including flattening (73.3% vs. 75%), irregularity (36.7% vs. 48.3%), sclerosis (20% vs. 8.3%), cyst (3.3% vs. 3.3%), erosion (13.3% vs. 21.7%), hypoplasia (3.3% vs. 5%), ankylosis (1.7% vs. Zero), osteophyte (43.3% vs. 40%), decrease joint space (3.3% vs. 3.3%), and increase joint space (5% vs. 5%). (p> 0.05) Conclusion: By employing CBCT as a modern diagnostic imaging tool, findings of this study revealed that the frequency of various temporomandibular joint alterations on CBCT images is comparable in patients with and without TMD complaints, suggesting that some people with TMJ structural damage may not display clinical manifestations. Moreover, CBCT imaging might not be necessary for TMD patients and more attention should be given to clinical examination.
Network Pharmacology-Based Approach to Investigate the Mechanisms of Hedyotis diffusa Willd. in the Treatment of Gastric Cancer

Background Hedyotis diffusa Willd. (HDW) is one of the renowned herbs often used in the treatment of gastric cancer (GC). However, its curative mechanism has not been fully elucidated. Objective To systematically investigate the mechanisms of HDW in GC. Methods A network pharmacology approach mainly comprising target prediction, network construction, and module analysis was adopted in this study. Results A total of 353 targets of the 32 bioactive compounds in HDW were obtained. The network analysis showed that CA isoenzymes, p53, PIK3CA, CDK2, P27Kip1, cyclin D1, cyclin B1, cyclin A2, AKT1, BCL2, MAPK1, and VEGFA were identified as key targets of HDW in the treatment of GC. The functional enrichment analysis indicated that HDW probably produced the therapeutic effects against GC by synergistically regulating many biological pathways, such as nucleotide excision repair, apoptosis, cell cycle, PI3K/AKT/mTOR signaling pathway, VEGF signaling pathway, and Ras signaling pathway. Conclusions This study holistically illuminates the fact that the pharmacological mechanisms of HDW in GC might be strongly associated with its synergic modulation of apoptosis, cell cycle, differentiation, proliferation, migration, invasion, and angiogenesis.
Exaggerated groups: amplification in ensemble coding of temporal and spatial features

The human visual system represents summary statistical information (e.g. average) along many visual dimensions efficiently. While studies have indicated that approximately the square root of the number of items in a set are effectively integrated through this ensemble coding, how those samples are determined is still unknown. Here, we report that salient items are preferentially weighted over the other less salient items, by demonstrating that the perceived means of spatial (i.e. size) and temporal (i.e. flickering temporal frequency (TF)) features of the group of items are positively biased as the number of items in the group increases. This illusory ‘amplification effect’ was not the product of decision bias but of perceptual bias. Moreover, our visual search experiments with similar stimuli suggested that this amplification effect was due to attraction of visual attention to the salient items (i.e. large or high TF items). These results support the idea that summary statistical information is extracted from sets with an implicit preferential weighting towards salient items. Our study suggests that this saliency-based weighting may reflect a more optimal and efficient integration strategy for the extraction of spatio-temporal statistical information from the environment, and may thus be a basic principle of ensemble coding.
Evaluating the Frequency of aac(6′)-IIa, ant(2″)-I, intl1, and intl2 Genes in Aminoglycosides Resistant Klebsiella pneumoniae Isolates Obtained from Hospitalized Patients in Yazd, Iran

Background: Klebsiella pneumoniae (K. pneumoniae) is an opportunistic pathogen that could be resistant to many antimicrobial agents. Resistance genes can be carried among gram-negative bacteria by integrons. Enzymatic inactivation is the most important mechanism of resistance to aminoglycosides. In this study, the frequencies of two important resistance gene aac(6′)-IIa and ant(2″)-I, and genes coding integrase I and II, in K. pneumoniae isolates resistant to aminoglycosides were evaluated. Methods: In this cross-sectional study, an attempt was made to assess the antibiotic susceptibility of 130 K. pneumoniae isolates obtained from different samples of patients hospitalized in training hospitals of Yazd evaluated by disk diffusion method. The frequencies of aac(6′)-IIa, ant(2″)-I, intl1, and intl2 genes were determined by PCR method. Data were analyzed by chi-square method using SPSS software (Ver. 16). Results: our results showed that resistance to gentamicin, tobramycin, kanamycin, and amikacin were 34.6, 33.8, 43.8, and 14.6%, respectively. The frequencies of aac (6′)-IIa, ant(2″)-I, intl1, and intl2 genes were 44.6, 27.7, 90, and 0%, respectively. Conclusion: This study showed there are high frequencies of genes coding aminoglycosides resistance in K. pneumoniae isolates. Hence, it is very important to monitor and inhibit the spread of antibiotic resistance genes.
Implementation of Low Glycemic Index Diet Together with Cornstarch in Post-Gastric Bypass Hypoglycemia: Two Case Reports

Post-bariatric hypoglycemia (PBH) is an increasingly recognized long-term complication of bariatric surgery. The nutritional treatment of PBH includes a high-fiber diet and the restriction of soluble and high-glycemic index carbohydrates; however, these measures are not always enough to prevent hypoglycemia. We evaluated the efficacy of uncooked cornstarch, a low-glycemic index carbohydrate characterized by slow intestinal degradation and absorption, in addition to a high-fiber diet, for the treatment of PBH. We report the cases of two young women suffering from severe postprandial and fasting hypoglycemia following Roux-en-Y gastric bypass (RYGB). The patients underwent Continuous Glucose Monitoring (CGM) before and 12–16 weeks after the administration of uncooked cornstarch (respectively 1.25 g/kg b.w. and 1.8 g/kg b.w.) in addition to a high-fiber diet. In both patients, CGM showed more stable glucose levels throughout monitoring, a remarkable reduction of the time spent in hypoglycemia (<55 mg/dL) both during the day (−11% for both patients) and the night (−22% and −32%), and the improvement of all glycemic variability indexes. Our report, within the limit of only two cases, suggests that the implementation of a dietary intervention through the addition of uncooked cornstarch reduces daily glycemic fluctuations and hypoglycemic episodes in patients with PBH.