Miracle-dz/UniFAR-FTUs huggingface dataset:
Intrapersonal and interpersonal factors in athletic performance *

Psychologically athletic performance is a multiplicative function of intrapersonal (for example, intrinsic motivation) and interpersonal (for example, social support) factors. It is theorized that the layer immediately surrounding an athlete's inner core of psychological functioning consists of 4 intrapersonal factors: self‐motivation, cognitive capacity and coping skills, affective orientation and mental training skills. The layer surrounding these factors is comprised of interpersonal factors, such as social support and the athlete‐coach relationship. A theoretical model was advanced to show that competition‐generated intrinsic motivation predisposition and social support are the two main properties of the athletic competition context that buffer against increased athletic and life stress. If such buffering effects occur, athletes' physical and psychological capacity is maintained or even enhanced. This in turn promotes continued competitive athletic participation and performance. Maximization of psychological conditions for successful performance requires that coaches foster athletes' intrapersonal and interpersonal psychosocial resources by serving as facilitators of their autonomous self‐regulation rather than as controllers of their goals and behaviors.
Dynamic 99mTc-MAG3 renography: images for quality control obtained by combining pharmacokinetic modelling, an anthropomorphic computer phantom and Monte Carlo simulated scintillation camera imaging

In dynamic renal scintigraphy, the main interest is the radiopharmaceutical redistribution as a function of time. Quality control (QC) of renal procedures often relies on phantom experiments to compare image-based results with the measurement setup. A phantom with a realistic anatomy and time-varying activity distribution is therefore desirable. This work describes a pharmacokinetic (PK) compartment model for 99mTc-MAG3, used for defining a dynamic whole-body activity distribution within a digital phantom (XCAT) for accurate Monte Carlo (MC)-based images for QC. Each phantom structure is assigned a time-activity curve provided by the PK model, employing parameter values consistent with MAG3 pharmacokinetics. This approach ensures that the total amount of tracer in the phantom is preserved between time points, and it allows for modifications of the pharmacokinetics in a controlled fashion. By adjusting parameter values in the PK model, different clinically realistic scenarios can be mimicked, regarding, e.g., the relative renal uptake and renal transit time. Using the MC code SIMIND, a complete set of renography images including effects of photon attenuation, scattering, limited spatial resolution and noise, are simulated. The obtained image data can be used to evaluate quantitative techniques and computer software in clinical renography.
Beyond the initial axon segment of the spinal motor axon: fasciculated microtubules and polyribosomal clusters

Dense undercoating, microtubular fascicles and scattered polyribosomal clusters have until now been considered to be the three structural features of the initial segment, and were thought not to extend beyond the initial segment into the myelinated parts of the axon. The aim of the present study was to make clear whether there is a sudden change in morphology between the unmyelinated and myelinated part. We followed spinal motor axons from the initial segment to the first internode by conventional electron microscopy and serial sectioning, and found that the microtubular fascicles and polyribosomal clusters do exist in the internodal axoplasm. The fasciculated microtubules were observed mainly in the first paranode. The polyribosomal clusters were found along the course of the first internode at a random distance, however, they occurred mainly in the proximal part of the first internode. The proportion of sections in which ribosomes were found, i.e. the incidence of ribosomes, in the first 30‐µm‐long portion was 71 ± 24% (mean ± SD, n = 4), and significantly different from that in the second 30‐µm‐long portion (3.2 ± 1.3%) (mean ± SD, n = 4) (P < 0.005). The more distal part of the first internode was not investigated.
Patterns of tibial rotary torque in knees of healthy subjects.

ABSTRACT OSTERNIG, LOUIS R. , BARRY T. BATES, and STANLEY L. JAMES. Patterns of tibial rotary torque in knees of healthy subjects. Med. Sci. Sports Exercise. Vol. 12, No. 3, pp. 195–199, 1980. Discrepancies in measures of active tibial rotation have been attributed to methodological variability and failure to adequately control accompanying foot and thigh motion. The purpose of this study was to assess maximum active tibial rotation on twenty-eight males utilizing a technique designed to stabilize the foot and thigh. Eversion and inversion motions of the talocalcaneal joint were controlled by means of a special boot connected to an isokinetic dynamometer modified with a position potentiometer. The results revealed symmetry between contralateral limbs with mean total ranges of motion of 57° and 59° for the right and left legs, respectively when tested and 90° of knee flexion and 50° at 45° of flexion. Converting these data to internal and external rotary components disclosed significant discrepancies (21–38%) between two methods applied to determine rotary neutral position. No significant differences were found between contralateral limbs for maximum torque development at all positions measured. Both range of motion and torque were found to be less at 45° of knee flexion when compared to the 90° position. Force data showed that all subjects consistently generated 90–100% of their peak torque within the initial 5–10° of active rotation and sustained relatively high torque values throughout an additional 15–20° before sharply reducing force magnitudes. These data support the concept of “wind up” effect of the medial and lateral hamstring muscles contributing to the rapid development of torque. Symmetrical patterns of contralateral limbs in torque and range of motion indicate that post-surgical comparisons with the unoperated limb to assess certain functional states of the knee may be reasonably accurate.
Immediate functional loading of Brånemark System implants with enhanced initial stability: a prospective 1- to 2-year clinical and radiographic study.

BACKGROUND The interest in the benefits of immediate loading of titanium implants has recently involved fixed prostheses for partially edentulous areas. The advantages of this approach well justify the need for extending the procedure to all regions of the mouth. Current available clinical literature on this subject is incomplete. PURPOSE The purpose of this study is to investigate the clinical outcome of the immediate loading of Brånemark System implants (Nobel Biocare AB, Gothenburg, Sweden) inserted with enhanced initial stability principally in posterior sites (78%). MATERIALS AND METHODS The present study was conducted in 26 consecutively treated patients. A total of 50 Brånemark System machined surface implants were placed supporting 30 fixed temporary partial dentures in light occlusion. All implants were followed up for a minimum of 1 year of function. Minimum requirements for immediate loading were proposed. Bone quality and quantity were classified according to Lekholm and Zarb's criteria. Stability of the marginal bone level, both mesial and distal, was measured on the basis of radiographic analysis. Implant survival rate was calculated according to Kaplan-Meier analysis. The peak insertion torque employed during fixture placement was between 40 and 72 Ncm, except in the case of one implant that was lost. RESULTS Overall survival rate was 98%. An unpaired t-test revealed bone remodeling conforming to biologic width establishment (p <.005). CONCLUSIONS Within the limit of this study, immediate loading appears to be a viable procedure in posterior sites and for a growing number of clinical indications. Enhanced implant stability and light occlusion seem to be security factors. In spite of unfavorable conditions such as the presence of quality 4 bone and a lack of splinting, all implants with enhanced primary stability survived.
Antimicrobial Activity of Divercin RV41 Produced and Secreted by Lactococcus lactis

Divercin V41 is a class IIa bacteriocin produced by Carnobacterium divergens V41 with a strong anti-Listeria activity. We have previously produced a recombinant form of divercin V41 (DvnRV41) in Escherichia coli strain Origami, by cloning a synthetic gene that codes for a mature divercin RV41 peptide. In this work we describe the inducible expression and secretion of DvnRV41 in the food-grade lactic acid bacterium, Lactococcus lactis. The production of DvnRV41 by recombinant L. lactis was confirmed and quantified by Western blot and ELISA assays. In addition, anti-Listeria activity of DvnRV41 was determined using an agar diffusion test. Although the levels of DvnRV41 produced by recombinant L. lactis were similar to those produced by the natural host, C. divergens V41, the specific activities were lower. In conclusion, our data show that the bacteriocin DvnRV41 is produced and secreted in an active form by L. lactis and that this approach may have important applications in the preservation of foods.
Gene Transfer of Interleukin 10 to the Murine Cornea Using Electroporation

Gene therapy is a promising approach to deliver anti-inflammatory genes to the eye to treat a number of corneal diseases. We have used electroporation to deliver plasmids expressing interleukin 10 (IL-10) to the corneas of mice and evaluated the duration of expression following gene transfer. Unlike expression of reporter genes driven from the cytomegalovirus immediate early promoter (CMViep), which remained high for 3 days, CMViep-driven IL-10 expression peaked at Day 1 and decreased 2-fold each day thereafter. In an attempt to increase the duration of expression, the long-acting ubiquitin C (UbC) promoter was used but, surprisingly, a similar half-life of gene expression was observed. This reduced duration was not due to promoter inhibition by expressed IL-10 or clearance of plasmids from the cornea. However, when DNA nuclear targeting sequences (DTSs) that promote DNA nuclear import were removed from the plasmids, contrary to findings in nondividing cells and tissues in which these sequences are needed for gene transfer, robust expression was observed, and the duration increased significantly. Although corneal cell turnover was detected, suggesting mitosis-dependent plasmid nuclear localization independent of a DTS, the patterns of expressing and dividing cells appeared different. These results suggest that DNA nuclear targeting sequences may act differently in the cornea than in other tissues.
Moving Glass Patterns: Asymmetric Interaction between Motion and form

The perceived motion direction of a moving Glass pattern is influenced by the orientation of the dot pairs (dipoles) that generate the pattern (Krekelberg et al, 2003 Nature 424 674–677; Ross, 2004 Vision Research 44 441–448). Here, we investigate how the motion vector and the dipole orientation of moving Glass patterns influence the perceived orientation of each. We employed 1 s movie presentations of sequences of linear Glass patterns, each consisting of 200 dot pairs. Signal pairs, aligned in a common orientation, moved in a common direction. The observer's task was to indicate either the perceived direction of motion, or the perceived dipole orientation of Glass patterns that consisted of either same-polarity dipoles, or opposite-polarity dipoles. Perceived orientation or motion direction was measured as a function of the angular difference between the orientation and the motion direction of the dipoles. We found that the apparent global direction of motion was attracted by approximately 4° towards the dipole orientation for small (15°, 23°) angular differences between dipole motion-direction and dipole orientation, regardless of dipole polarity. However, under the same stimulus conditions, the apparent global orientation was much less affected by the direction of motion, suggesting that motion and form interact asymmetrically. Global form influences global motion-direction perception more powerfully than global motion influences global form perception.
Teleporting an unknown quantum state via dual classical and Einstein-Podolsky-Rosen channels.

An unknown quantum state \ensuremath{\Vert}\ensuremath{\varphi}〉 can be disassembled into, then later reconstructed from, purely classical information and purely nonclassical Einstein-Podolsky-Rosen (EPR) correlations. To do so the sender, ``Alice,'' and the receiver, ``Bob,'' must prearrange the sharing of an EPR-correlated pair of particles. Alice makes a joint measurement on her EPR particle and the unknown quantum system, and sends Bob the classical result of this measurement. Knowing this, Bob can convert the state of his EPR particle into an exact replica of the unknown state \ensuremath{\Vert}\ensuremath{\varphi}〉 which Alice destroyed.
The multikey type index for persistent object sets

Multikey index structures for type hierarchies are a recently discussed alternative to traditional B/sup +/-tree indexing schemes. We describe an efficient implementation of this alternative called the multikey type index (MT-index). A prerequisite for our approach is an optimal linearization of the type hierarchy that allows us to map queries in object type hierarchies to minimal-volume range queries in multi-attribute search structures. This provides access to an already-existing large and versatile tool-box. The outline of an index implementation by means of a multi-attribute search structure (e.g. the hB-tree or any other structure with comparable performance) is followed by an analytical performance evaluation. Selected performance figures are compared to previous approaches, in particular to the H-tree and the class hierarchy tree. The comparison results allow for practically relevant conclusions with respect to index selection based on query profiles.
Impact of Naringenin on Oxytetracycline-Mediated Oxidative Damage in Kidney of Rats

The aim of this study was to investigate the effect of naringenin on oxytetracycline-induced nephrotoxicity in rats. Oxytetracycline (200 mg/kg body weight, ip) was administered in 0.5ml of sterile physiological saline for 15 days, resulting in a significant increase in serum urea and creatinine and reduction in creatinine clearance. A significant increase in lipid peroxidation markers (TBARS and lipid hydroperoxide) and decrease in antioxidant enzymes (superoxide dismutase, catalase, and glutathione peroxidase) and low molecular weight antioxidants (vitamin C, vitamin E, and reduced glutathione) levels were also observed in oxytetracycline-treated rats. The oral administration of naringenin (50 mg/kg body weight) attenuated the oxytetracycline-induced nephrotoxicity by significantly decreased levels of serum urea and creatinine with the significant normalization of creatinine clearance. Upon the administration of naringenin, the depleted renal antioxidant defense system (enzymatic and non-enzymatic antioxidants) was significantly increased in rats treated with oxytetracycline. These biochemical observations were supplemented by histopathological examination of kidney section. The present results suggest that the supplementation of naringenin might be helpful to alleviate the oxytetracycline-induced oxidative injury in kidney.
Prevalence of low back pain in non working rural housewives of Kanpur, India.

OBJECTIVES Housewives are nucleus of families but as the working, living, and social architecture in the rural areas significantly differ from developed or urban area, the results of urban population cannot be generalized. Hence the purpose of the present study is to evaluate the prevalence of low back pain in non working rural housewives. Also an attempt has been made to determine the impact of social burden on low back pain (LBP). MATERIAL AND METHODS A sample of 301 non working rural housewives of Kanpur, aged between 30-70 years was selected. Hindi version of 3 appropriate scales Nordic musculoskeletal questionnaire, Oswestry disability index and Zarit burden interview measuring musculoskeletal discomfort, low back disability and social burden were given to all the housewives. RESULTS Analysis of data reveals that both recent and yearly prevalence of LBP in rural housewives is 83%. More than 50% housewives have severe disability due to their LBP. Correlational analysis has shown that there is a significant impact of social burden on their disability due to low back pain. CONCLUSIONS The findings of the present study suggest that 83% of the non working rural housewives have low back pain and activity restriction due to their pain. They have significant impact of social burden on their low back pain. High prevalence (83%) of low back pain among rural housewives is an alarming sign for our society. Better health-care measures to enhance rural housewives education about good posture, ergonomic measures, health schemes, health awareness, and activity pacing could help rural housewives.
Pathogenesis of rotavirus infection in mice

Three parameters of rotavirus infection, i.e., clinical disease, viral antigen in infected intestines, and infectious virus in feces, were assessed in infant mice nursed by mothers with or without preexisting rotavirus antibody. Diarrhea was the only consistent sign of clinical disease, and its course followed that of infection by about 1 day. Infected intestinal epithelial cells, except crypt cells, were observed by immunofluorescence microscopy in the duodenum, jejunum, ileum, and colon. Infection progressed in a proximal-to-distal direction with time. Viral antigen appeared in intestinal tissue later, was present in lower amounts, and disappeared sooner from infants nursed by mothers with preexisting rotavirus antibody, indicating that protection was passively transferred to these infants although the course of clinical disease was not changed.
Activity of Bay y3118 against quinolone-susceptible and -resistant gram-negative and gram-positive bacteria

The activity of Bay y3118 against laboratory strains of bacteria, including those with mutations in gyrA, with decreased expression of outer membrane proteins, and/or that are multiply resistant, and 121 selected clinical isolates, including highly fluoroquinolone-resistant bacteria from Spain and Argentina, was determined. Bay y3118 was extremely active (MICs, < or = 1 microgram/ml) against all bacteria, including quinolone-resistant laboratory strains. However, Bay y3118 was less active against 46 of 121 quinolone-resistant clinical isolates, such that > or = 16 micrograms of Bay y3118 per ml was required to inhibit 3 isolates. The concentration of Bay y3118 required to inhibit DNA synthesis by 50% correlated well with the MIC. Bay y3118 had accumulation kinetics similar to those of previously studied fluoroquinolones, e.g., ciprofloxacin, and there was a 50% decrease in the steady-state concentration in those members of the family Enterobacteriaceae that lacked porin proteins. Magnesium chloride at 20 mM apparently abolished the accumulation of Bay y3118 into Escherichia coli and reduced the level of accumulation into other gram-negative bacteria and Staphylococcus aureus. Carbonyl cyanide m-chlorophenylhydrazone at 100 microM enhanced the accumulation of Bay y3118 into E. coli, but it had a minimal effect on accumulation into S. aureus.
High prevalence of human papillomavirus type 58 in patients with cervical pre‐malignant lesions in southern Brazil

Cervical cancer is the second most common type of cancer in women worldwide. Several human papillomavirus (HPV) genotypes, sexual behavior, and socioeconomic profile represent major risk factors for the development of this carcinoma. Cervical invasive cancer is preceded by cellular abnormalities that can be identified by cytological or histological exams. In order to determine the prevalence and genotypes of HPV in women with abnormal cytology or histopathology, cervical cell samples from 256 patients were evaluated for the presence of HPV/DNA by polymerase chain reaction (PCR), followed by virus genotyping by restriction fragment length polymorphism (RFLP). A total of 113 samples (51.2%) were HPV/DNA positive. Viral genotyping showed that the most prevalent genotypes were HPV 16 (34.7%) and 58 (13.8%), followed by HPV 33 (9.72%), 11 (8.33%), 18 (5.55%), 53 (5.55%), and 6 (4.2%). Four samples (5.55%) exhibited multiple infections due to the great similarity of socioeconomic characteristics and sexual behavior of HPV positive women, it was not possible to establish a risk profile for female HPV infection. J. Med. Virol. 81:1270–1275, 2009. © 2009 Wiley‐Liss, Inc.
Low cortisol levels and the balance between punishment sensitivity and reward dependency

The neuro-endocrinological basis of psychopathy, a disorder characterized by lack of fear, is relatively unknown. However, low levels of cortisol may result in fearlessness and have been observed in individuals with psychopathic tendencies. Low fear models state that psychopaths are not motivated to avoid punishment, especially when reward is pending. In agreement, disadvantageous decision making on the IOWA gambling task in psychopaths and psychopathic analogous, indicates low punishment sensitivity and high reward dependency. Here, it was investigated whether low basal cortisol levels predicted the balance between punishment sensitivity and reward dependency in the same manner. As hypothesized, the most disadvantageous pattern of decision making was found in the subjects with the lowest cortisol levels. These findings suggest that low levels of cortisol may set the balance between the sensitivity for punishment and reward dependency towards a pre-disposition for psychopathy.
A clinicoanatomical study of the arcuate ligament of the diaphragm.

Seventy-five fresh autopsy specimens were carefully studied and analyzed relative to the relationship between the arcuate ligament of the diaphragm and the celiac artery, the celiac plexus, and the inferior phrenic arteries. The following observations were made: (1) that the celiac ganglionic cuirass often participates in arterial compression, (2) that the celiac artery origin was at or above the median arcuate ligament in up to 25 (33%), (3) that this was due to a low ligament rather than a high artery, and (4) that it is more common in mesomorphs and endomorphs and in females. The ligament was exceedingly variable in character. Autonomic nerves were found closely associated with it.
Sample Size Requirements for Structural Equation Models

Determining sample size requirements for structural equation modeling (SEM) is a challenge often faced by investigators, peer reviewers, and grant writers. Recent years have seen a large increase in SEMs in the behavioral science literature, but consideration of sample size requirements for applied SEMs often relies on outdated rules-of-thumb. This study used Monte Carlo data simulation techniques to evaluate sample size requirements for common applied SEMs. Across a series of simulations, we systematically varied key model properties, including number of indicators and factors, magnitude of factor loadings and path coefficients, and amount of missing data. We investigated how changes in these parameters affected sample size requirements with respect to statistical power, bias in the parameter estimates, and overall solution propriety. Results revealed a range of sample size requirements (i.e., from 30 to 460 cases), meaningful patterns of association between parameters and sample size, and highlight the limitations of commonly cited rules-of-thumb. The broad “lessons learned” for determining SEM sample size requirements are discussed.