Miracle-dz/UniFAR-FTUs huggingface dataset:
Learning with artificial worlds: computer based modelling in the curriculum

From the Publisher: This book is about modelling in education and providing children with computer tools to enable them to create their own worlds, to express their own representations of their world, and also to explore other people's representations. It is about learning with artificial worlds. With the advent of the National Curriculum computer-based modelling is now an integral part of the school curriculum. Teachers are increasingly being encouraged to seek out opportunities for CBM in their own subject and across the curriculum. These new demands have left teachers and teacher trainers concerned as to their lack of experience in this area. This book sets out to provide a comprehensive guide to the area through a very novel approach by classifying modelling into three different kinds, dependent on what is involved in the activity: quantitative, qualitative and semi-quantitative modelling. This books goes beyond any present published work in the area of computer modelling.
of the Annual Meeting of the Cognitive Science Society Title Infant Familiarization to Artificial Sentences : Rule-like Behavior Without Explicit Rules and Variables

A recent study of infant familiarization to artificial sentences claimed to produce data that could only be explained by symbolic rule learning and not by unstructured neural networks. Here we present successful unstructured neural network simulations showing that these data do not uniquely support a rule-based account. In contrast to other neural network simulations, our simulations cover more aspects of the data with fewer assumptions using a more realistic coding scheme based on sonority of phonemes. Our networks show exponential decreases in attention to a repeated sentence pattern, more recovery to novel inconsistent sentences than to novel consistent sentences, some preference reversals, and extrapolation. One of the most simulated phenomena in developmental psychology is a data set that was claimed to be immune from simulation by unstructured neural networks (Marcus, Vijayan, Bandi Rao, & Vishton, 1999). Although the authors maintained that their results could only be explained by explicit rules and variables, there are now at least eight connectionist simulations of the data, most of which do not use explicit variable binding and none of which use explicit rules. Here we present additional neural simulations of these data, arguing that our model may provide the currently most satisfying account. The paper reviews the relevant infant data, presents various interpretations and models, and then focuses on our current model.
Cellules suppressives d'origine myéloïde au cours du sepsis

Le sepsis est a l’origine d’une dysfonction immunitaire prolongee responsable d’infections nosocomiales et d’une mortalite tardive elevee. Sa physiologie complexe demeure mal connue et il n’existe aucun traitement specifique en dehors de l’antibiotherapie et des therapeutiques de suppleance d’organes. Nous nous sommes interesses au role des cellules myeloides dans cette dysfonction immunitaire. Nous avons pu montrer qu’il existe chez les patients atteints de sepsis une augmentation du nombre de cellules suppressives d’origine myeloide monocytaires (M-MDSC) CD14+HLA-DRlow/- et granulocytaires (G-MDSC) identifiees comme des granulocytes de faible densite CD14-CD15+. Ces cellules sont responsables d’une activite Indoleamine 2,3-dioxygenase (IDO) et arginase 1, et leur depletion permet de restaurer la proliferation des lymphocytes T in vitro. L’augmentation precoce des G-MDSC predit la survenue ulterieure d’infections nosocomiales. De meme, l’augmentation de l’activite IDO et de l’arginase 1 plasmatique sont associees a un mauvais pronostic. Au total, nous avons pu demontrer que les cellules myeloides acquierent un phenotype suppresseur en partie responsable de l’immunodepression acquise et du pronostic pejoratif chez les patients septiques. Afin de restaurer les capacites immunitaires des patients, les MDSC pourraient devenir une future cible therapeutique.
METHODS PE TEACHERS USE TO INCLUDE PUPILS WITH SPECIAL EDUCATIONAL NEEDS AND THEIR PERCEPTIONS OF THEIR INCLUSION

1 This form should be used for both quantitative and qualitative dissertations. The descriptors associated with both quantitative and qualitative dissertations should be referred to by both students and markers. 2 There is scope within qualitative dissertations for the RESULTS and DISCUSSION sections to be presented as a combined section followed by an appropriate CONCLUSION. The mark distribution and criteria across these two sections should be aggregated in those circumstances. Hannah Walker St20022727
In vitro antisickling and radical scavenging activities of a poly-herbal formula (Drepanoalpha®) in sickle cell erythrocyte and acute toxicity study in wistar albino rats.

Aims: To evaluate the antisickling and radical scavenging activities and acute toxicity of indigenous nutritive formula Drepanoalpha®, produced through a bio-guided based plant selection. Study Design: Drepanoalpha extracts, Antisickling activity by Emmel test, Antioxidant activity by 1,1-diphenyl-2-picrylhydrazyl bleaching methods; acute toxicity on rats, determination of biological and haematological parameters. Place and Duration of Study: Science Faculty University of Kinshasa, between January 2013 and February 2014. Methodology: The antisickling and antioxidant activities of Drepanoalpha were determined using Emmel and the 1,1-diphenyl-2-picrylhydrazyl bleaching methods Original Research Article European Journal of Medicinal Plants, 4(10): 1251-1267, 2014 1252 respectively. Acute oral toxicity test was performed to determine the LD50. Liver and kidney functions, the hematological and histopathological examinations were assessed using standard techniques. Results: Obtained results revealed that Drepanoalpha possessesinteresting in vitro antisickling and antioxidant activities as revealed by the observed normal biconcave form of sickle erythrocyte (normalization rate >80%) and the radical scavenging activity (ED50= 0.604 ± 0.028 μg/mL). Acute toxicity assessment revealed that the medium lethal dose (LD50) is higher than 4000 mg/kg. Drepanoalpha significantly increases the values of WBC, RBC, Hb, HCT, PLT, IDR-CV and PCT. Furthermore, this polyherbal formula significantly decreases the values of IDR-SD, P-RGC, AST and ALT (p<0.05). Both the control and treated groups displayed comparable non altered histological architecture of the liver cells. Discussion: The mean values of biochemical markers and hematological markers of treated rats revealed that Drepanoalpha is potentially safe indicating non-toxic effect of the phytomedicine on immune cells and blood clotting factors. Moreover, this poly-herbal formulation increases the hemoglobin rate in the all treated rats (500-4000 mg/kg bodyweight) and preserves the histological architecture of the liver cells. Conclusion: Drepanoalpha may increase weight gain, promote erythropoiesis and thrombopoeisis in sicklers patients. This phytomedicine could be used in the treatment of all form of anemia and may also prevent bile duct obstruction or intra-hepatic cholestasis. The results can form the basis for clinical trials in humans.
A Study on the Function of Blood Pressure Regulation among the Younger Generation in Japan

Recently, it is feared that the fitness for protection of the younger generation in Japan will fall down. The purpose of this study was to clarify the blood pressure regulation by utilizing a regulating reflex method of blood pressure among younger generation in Japan. The study was made on 430 students, the 7th to the 9th grade at junior high school in Tokyo, from February to June 1995. The results were summarized as follows: 1) The ratio of poor function in blood pressure regulation increased in comparison with the result of the investigations carried out in 1956 and 1984. 2) The blood pressure partly didn't drop just after the changing position from the lying to the sitting posture. The blood pressure didn't recover up to the resting value, even if 180 seconds passed after changing posture. A predominance of sympathetic nervous system was suggested. 3) It is necessary to reexamine the traditional criterion of regulating reflex method of blood pressure. 緒言 わが国で は,1964年 以 来,ス ポー ツテ ス ト(体 力診 断テ ス ト,運動能力 テス ト)が 実施 され,学 校での 「体 エア 力つ くり」 の取 り組みが全 国的に行われて きた 。 そ の結果 を見 る限 り,柔 軟性 の低 下や小学生の運動能力 の低下 など若干 の体力要素等 にア ンバ ランスがみ られ る もの の,「 行 動体 力」の 水準 は,調 査開 始時点 と 比べて一段 と高 くな り,そ の水準 がなん とか維持 され てい る 。 しか しなが ら,「 子 ど もの体 力が低 下 して いる」 と い っ実感 は現在 で もなお根強 く残 って いるので, 我々 はその実体 と して 「防衛体 力」 の低下 を予想 し, その一端 につ いて調査 を行 って きた 。 福 田 は,疲 労 が脳幹 に及んだ場合,体 位変換の際 に起 こる動脈血圧 の低下 を回復 させ る血圧調節機能が 不 良になることに着 目 し,疲 労判定法の一つに 「体位 血圧反射法」 と名付 けた方法 を提案 した。 しか しなが ら,こ の 「体位血圧反射法」 を活用 した疲労研究 はこ れ まで ほとんどな く,む しろ,循 環機能の応答特性 を 検査す るといっ研究 が多い。 猪飼 ら は,6~55歳 の年齢 にわたる健康 人につ い て,体 位血圧反射法 を用いて血圧調節機能 を調査 した 結果,こ の機能が発育 とともに向上 し,老 年 に至 って 再 び低下す る傾向にある ことを報告 した。 ところが, * 日 本 体 育 大 学 Nippon Sport Science University, Fukasawa 7-1-1, Setagaya-ku, Tokyo,158, Japan
Compliance Among Adolescents During Drug Treatment

ABSTRACT Research on adolescent drug treatment engagement is scarce; however, such research on adults suggests that successful engagement in treatment increases the likelihood of positive treatment outcomes. Compliance during drug treatment reflects treatment engagement. We examined self-assessed compliance (agreement with treatment goals, meeting treatment staff expectations, and following treatment staff instructions), behavioral compliance (staying for the duration of planned treatment), and their influences, among adolescents in treatment. Stepwise logistic regression showed that desire for help was significantly (p < 05) related to more compliance. Compared with those in residential treatment, those in inpatient treatment were more likely to agree with treatment goals, to follow instructions, and to stay for the planned duration of treatment; those in outpatient treatment were more likely to meet treatment expectations. Psychological maladjustment was related to less self-perceived compliance. We discuss the implications of these findings for adolescent treatment engagement.
Robust Vehicle and Surrounding Environment Dynamic Analysis for Assistive Driving Using Visual-Inertial Measurements

Vehicle and surrounding environment dynamic analysis (VSEDA) is an indispensable component of modern assistive drivings. A robust and accurate VSEDA could ensure the driving system reliability in presence of highly dynamic environments. This paper proposes a novel VSEDA framework by fusing the measurements from an inertial sensor and a monocular camera. Compared to traditional visual-inertial-based assistive driving methods, the proposed approach can analyze both the vehicle dynamics and the surrounding environment. Even in the scenario that moving objects occupy a majority area of the scene captured in the image, the proposed method can still robustly analyze the surrounding environment by identifying the static inliers and dynamic inliers, which lie on stationary objects and moving objects, respectively. The theoretical framework consists of three steps. First, the vehicle nonholonomic constraint is applied to pairwise feature matching. For vehicle dynamic analysis, the static inliers are selected by choosing the features with their histogram bins consistent with inertial orientations. Second, for the surrounding environment dynamic analysis, the dynamic inliers are matched through histogram voting, together with the developed part-based vehicle detection model that can segment and match the vehicle regions from the background in image pairs. Finally, both the vehicle dynamics and surrounding environments are analyzed with static and dynamic inliers respectively. The proposed method has been evaluated on the challenging datasets, part of which was collected during rush hours in downtown areas. The experimental results prove the effectiveness and accuracy of the proposed VSEDA.
Radioresistance of cancer cells, integrin αvβ3 and thyroid hormone

Radioresistance is a substantial barrier to success in cancer management. A number of molecular mechanisms support radioresistance. We have shown experimentally that the thyroid hormone analogue receptor on the extracellular domain of integrin αvβ3 may modulate the state of radiosensitivity of tumor cells. Specifically, tetraiodothyroacetic acid (tetrac), a derivative of L-thyroxine (T4), can reduce radioresistance in cancer cells. In this review, we list a number of intrinsic signal transduction molecules and other host factors that have been reported to support/induce radioresistance in cancer cells and that are also subject to control by T4 through actions primarily initiated at integrin αvβ3. Additional preclinical evidence is needed to support these radioresistance-relevant actions of thyroid hormone.
HIV / AIDS knowledge, attitudes and behaviours of student nurses

Background: HIV and AIDS is a matter of concern because the number of cases has increased dramatically over the last ten years. Nursing students need to have appropriate knowledge and attitudes about HIV and AIDS because they are the future health care professionals, therefore will play a key role in prevention of spread and care of people with AIDS. The aim of the study was to explore the knowledge, behaviours and attitudes about HIV/AIDS of nursing students in Greece. Method and Material: A cross-sectional study was carried out in a nursing school of a Technological Educational Institute in Greece. A sample of 279 (N=279) nursing students agreed to participate in the study, giving a response rate of 77.5%. Data were collected using an anonymous questionnaire comprising four self-administered instruments: (a) the International AIDS questionnaire-Chinese Version (IAQ-C), (b) the source of HIV/AIDS information questionnaire, (c) Sexual behaviours/practices and attitudinal questions about AIDS and (d) demographic questions. Return of a completed questionnaire was considered as consent to participate in the study. Descriptive and inferential statistics were employed for the data analysis using SPSS version17. The significant level of p value was determined at p< 0.05 Results: Overall student nurses had fairly good knowledge about HIV and AIDS as well as a positive attitudes towards AIDS people (M=70.39;SD=18.43; possible range 18-90). A few items however presented contradictory results from the overall score of the knowledge scale. Of the respondents 39.8% believed that mosquitoes can transmit HIV and 38% believed the virus could be transmitted via the toilet seat. 56.2% reported that vaccination can protect them from AIDS. The majority of respondents (76.7%) hadn? t been taught about HIV/AIDS. Participants reporting a willingness to care for people with AIDS were significantly more knowledgeable and held more positive attitudes towards people with AIDS (P=0.001). The primary sources of information for the participants were television (80.7%), newspapers/magazines (64.6%) and internet (60%). 94.3% of the respondents stated that they were heterosexual and sexually active. Religious students were found to be less knowledgeable and held less positive attitudes towards people with AIDS when compared to students with no religious conviction (F=2.61; P=0.03). Conclusions: Student nurses? knowledge presented contradictory results which indicated that whilst overall scores confirmed the participants possessed fairly good knowledge, individual knowledge items demonstrated that they lacked some knowledge on the subject. Nursing curriculum programmes of nursing schools need to be restructured to ensure that students gain the necessary accurate knowledge and appropriate attitudes about HIV and AIDS.
Student and Faculty Perception of Objective Structured Clinical Examination: A Teaching Hospital Experience

Introduction: The primary objective of this study was to explore student and faculty perception of the objective structured clinical examination (OSCE) to assess the clinical competence of 5th year medical students. Methods: Two validated tools were used to survey students' and faculty perception of the OSCE as an assessment tool. The questionnaires were self-administered and handed to the students immediately after the OSCE was conducted. Subjects were 29 female students who had completed their 3-week Internal Medicine rotation and 15 faculty members who had participated in evaluating the students. The response rate was 100%. The OSCE comprised of 21 active stations involving skills like history taking standardized patients were used, physical examination, and data interpretation for which real patients were used. Results: Majority of students, 63.2% indicated that the OSCE assessed their skills fairly. This was also true for 80% thought the OSCE was a fair method of assessing students' skills as well as a better assessment tool than the traditional long/short case exams. Conclusion: The OSCE was positively perceived by 5th year medical students and faculty members as a tool that can fairly assess students' clinical skills.
Risk of Exacerbation and Pneumonia with Single-Inhaler Triple versus Dual Therapy in IMPACT

Background To determine overall benefit-risk, we examined the effect of single inhaler fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) versus UMEC/VI and FF/VI on the composite outcome of acute exacerbation of COPD or pneumonia in the IMPACT study (NCT02164513, CTT116855), a 52 week, randomized, multicentre study in patients with symptomatic COPD and a history of exacerbations Methods We defined two composite outcomes: time to first moderate (required antibiotics and/or oral/systemic corticosteroids)/severe (required hospitalisation) exacerbation or pneumonia; and time to first severe exacerbation/hospitalised pneumonia. Analyses were based on a proportional hazards model. Results Moderate/severe exacerbations occurred in 47% of patients randomized to FF/UMEC/VI, 49% in those randomized to FF/VI and 50% in those randomized to UMEC/VI. Pneumonias occurred in 8%, 7%, and 5% of patients in these groups, respectively. FF/UMEC/VI reduced the risk of first moderate/severe exacerbation or pneumonia vs FF/VI by 13.2% (95%CI 7.8%–18.3%; p<0.001) and vs UMEC/VI by 13.1% (95%CI 6.3%–19.3%; p<0.001) as determined by a time to first analysis. There was no difference in the risk of a moderate/severe exacerbation or pneumonia between FF/VI and UMEC/VI. FF/UMEC/VI reduced the risk of a severe exacerbation or hospitalized pneumonia vs UMEC/VI by 16.9% (95%CI 4.2%–27.8%, p=0.011) as determined by a time to first analysis. There was no statistically significant difference in the risk of a severe exacerbation or hospitalized pneumonia between FF/UMEC/VI and FF/VI or between FF/VI and UMEC/VI. Conclusion These composite exacerbation/pneumonia outcomes support a favourable benefit-risk profile of once-daily FF/UMEC/VI compared with FF/VI and UMEC/VI in patients with moderate to severe COPD and a history of exacerbations. Funding GSK (CTT116855); This ENCORE abstract will be presented as a poster at the 2018 European Respiratory Society Meeting in September.
Education and quality of life of senior citizens

(editors) " Education and quality of life of senior citizens " This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. iii This guide is part of the " Evaluation toolkit on seniors' education to improve their quality of life " project (http://www.edusenior.eu). This project has been funded with support from the European Commission. This communication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein. Ageing is one of the greatest social and economic challenges to European societies in the 21st century. It will affect all Member States and it will cut across nearly all EU policy domains. By 2025 more than 20% of Europeans will be 65 or over 1 , with a particularly rapid increase in the number of citizens over 80 years old. Institutions that teach seniors (65+ years old or retired) need to address courses to a target group that is not aiming to get a degree or to improve their career opportunities. They must therefore apply different methodologies and also create specially designed courses, activities and materials. From a broader perspective, their main aim is to increase senior learners' well-being and quality of life (QoL). In this context, teaching becomes a socio-educational activity where more formal, non-formal and informal activities are blended. The knowledge students acquire is important, but other skills, attitudes and aims should not be forgotten such as socialisation, integration, adapting to society, active citizenship, etc. Existing research defines QoL in terms of both objective and subjective perceptions. Some parameters are available for evaluating QoL and, therefore, to take action to improve an individual's QoL. Levels of QoL may fall as a result of several kinds of risks (e.g. loneliness, isolation) and may rise due to 1 Giannakouris, K. (2008) Ageing characterises the demographic perspectives of the European societies, in Population and social conditions. Eurostat; Statistics in focus. 72/2008 Introduction 8 other activities that promote integration or communication. Education can be used to minimise the risks and maximise QoL. The promotion and enhancement of QoL in senior citizens is highly positive as it not only leads to happier seniors, but also to more active, productive, participative, healthy older people who require fewer social services and whose value in society is increased. This guide is addressed to teachers, trainers, tutors, facilitators, staff, technicians, managers and …
Training Medical Students in General Practices : Factors Influencing Patients’ Attitudes

Introduction: It is in the privacy of the consultation room that a patient divulges information regarding his/her illness to the doctor. Presence of students could compromise the privacy and intimacy and may prohibit a patient from revealing sensitive information and allowing internal examination. This study was conducted to explore factors affecting patients’ attitudes towards training students in general practices.
A Congestion Control Protocol in P2P Networks

Many of current P2P application tend to use UDP as their transport protocol. Since UDP does not provide congestion control mechanism, the developers of these applications have to decide how frequently to send UDP packet individually. It is necessary to provide a common congestion control protocol specially design for P2P networks. This paper proposes a protocol for such propose and use simulation to valid it