Miracle-dz/UniFAR-FTUs huggingface dataset:
Olive Leaves Extract Restored the antioxidant Perturbations in Red Blood Cells Hemolysate in Streptozotocin Induced Diabetic Rats

Oxidative stress and overwhelming free radicals associated with diabetes mellitus are likely to be linked with development of certain complication such as retinopathy, nephropathy and neuropathy. Treatment of diabetic subjects with antioxidant may be of advantage in attenuating these complications. Olive leaf (Oleaeuropaea), has been endowed with many beneficial and health promoting properties mostly linked to its antioxidant activity. This study aimed to evaluate the significance of supplementation of Olive leaves extract (OLE) in reducing oxidative stress, hyperglycemia and hyperlipidemia in Sterptozotocin (STZ)induced diabetic rats. After induction of diabetes, a significant rise in plasma glucose, lipid profiles except High density lipoproteincholestrol (HDLc), malondialdehyde (MDA) and significant decrease of plasma insulin, HDLc and Plasma reduced glutathione GSH as well as alteration in enzymatic antioxidants was observed in all diabetic animals. During treatment of diabetic rats with 0.5g/kg body weight of Olive leaves extract (OLE) the levels of plasma (MDA) ,(GSH), insulin, lipid profiles along with blood glucose and erythrocyte enzymatic antioxidant enzymes were significantly restored to establish values that were not different from normal control rats. Untreated diabetic rats on the other hand demonstrated persistent alterations in the oxidative stress marker (MDA), blood glucose, insulin, lipid profiles and the antioxidant parameters. These results demonstrate that OLE may be of advantage in inhibiting hyperglycemia, hyperlipidemia and oxidative stress induced by diabetes and suggest that administration of OLE may be helpful in the prevention or at least reduced of diabetic complications associated with oxidative stress. Keywords—Diabetes mellitus, olive leaves, oxidative stress, red blood cells
A physical model for the X-ray time lags of narrow-line Seyfert type 1 active galactic nuclei

We study the origin of the soft X-ray excess seen in the ‘simple’ narrow-line Seyfert 1 galaxy PG1244+026 using all available spectral-timing information. This object shows the now ubiquitous switch between soft leading the hard band on long time-scales, to the opposite behaviour on short time-scales. This is interpreted as a combination of intrinsic fluctuations propagating down through the accretion flow giving the soft lead, together with reflection of the hard X-rays giving the soft lag. We build a full model of the spectral and time variability including both propagation and reflection, and compare our model with the observed power spectra, coherence, covariance, lag-frequency and lag-energy spectra. We compare models based on a separate soft excess component with those based on reflection-dominated soft emission. Reflection-dominated spectra have difficulty reproducing the soft lead at low frequency since reflection will always lag. They also suffer from high coherence and nearly identical hard- and soft-band power spectra in disagreement with the observations. This is a direct result of the power-law and reflection components both contributing to the hard and soft energy bands, and the small radii over which the relativistically smeared reflection is produced allowing too much high-frequency power to be transmitted into the soft band. Conversely, we find the separate soft excess models (where the inner disc radius is >6Rg) have difficulty reproducing the soft lag at high frequency, as reflected flux does not contribute enough signal to overwhelm the soft lead. However, reflection should also be accompanied by reprocessing and this should add to the soft excess at low energies. This model can quantitatively reproduce the switch from soft lead to soft lag seen in the data and reproduces well the observed power spectra and other timing features which reflection-dominated models cannot.
The Mediating Role of Emotion Dysregulation in the Relation Between Adult Attachment Insecurity and Depression Among Young Gay and Bisexual Men

Abstract Objectives: Attachment insecurity may be more pronounced among young gay and bisexual men (YGBM). Further, attachment insecurity is associated with dysregulated patterns of emotion regulation, which can lead to depression. However, pathways linking attachment insecurity to depression are underexplored among YGBM. Methods: This study used pilot data from N = 67 YGBM to examine if emotion dysregulation mediated the association between attachment insecurity and depression. Results: Results supported the study hypotheses. Attachment insecurity was associated with emotion dysregulation, which was associated with depression. Conclusion: Findings provide preliminary evidence that emotion regulation training may be a useful approach for addressing depression among YGBM.
Plant Anaerobic Stress II. Strategy of Avoidance of Anaerobiosis and Other Aspects of Plant Life under Hypoxia and Anoxia

This review is a logical follow-up of previous publications (Vartapetian and Crawford 2007; Sachs and Vartapetian 2007) where an attempt was made to summarize the results of earlier periods of investigations of plant anaerobic stress and the activity of members of the International Society for Plant Anaerobiosis (ISPA) that ultimately brought about the establishment and international recognition of a new scientific discipline in the field of plant ecological physiology, biochemistry and molecular biology devoted to plant life under hypoxia and anoxia. Special attention was also paid to the strategy of metabolic adaptation of plants to hypoxia and anoxia, realized at the molecular level, including both the molecular biological and molecular genetic aspects of the problem. Continuing the discussion of strategies of plant adaptation to anaerobic environments in this review we pay particular consideration to the strategy of adaptation accomplished at the whole plant level by the formation of a continuous network of gas-filled spaces (aerenchyma), which development, provoked by specific signaling systems and programmed cell death, provides facilitated long-distance oxygen transport from aerated plant parts to organs (roots, rhizomes) under anaerobic conditions, that is a strategy of avoidance of anaerobiosis, or the phenomenon of “apparent” tolerance. Additionally, the following important aspects of plant hypoxic and anoxic stress are also considered here: postanaerobic plant injury by reactive oxygen species and protection against oxidative injury by plant antioxidants; the Davies-Roberts pHstat theory; alternative electron acceptors; demonstration of the adaptation syndrome in plants under anaerobic stress; and genetic and cellular engineering in generating plants tolerant to anaerobic stress.
Experimental Evaluation of Compressive Behavior of Orthotropic Steel Plates for the New San Francisco-Oakland Bay Bridge

Compression tests were conducted on two reduced-scale orthotropic plates to verify the design strength of steel box girders for the new San Francisco-Oakland Bay Bridge. The first specimen was composed of three longitudinal closed ribs and a top deck plate. It failed in global buckling, followed by local buckling in the deck plate and ribs. The second specimen, which was composed of four longitudinal T-shaped ribs and a bottom deck plate, experienced global buckling as well as local buckling in the ribs and the deck plate. The ultimate strength and failure mode of both specimens were evaluated by two bridge design specifications: the 1998 AASHTO load and resistance factor design specification and the 2002 Japanese JRA specification. Findings from code comparisons showed that: 1 Sufficient flexural rigidity of ribs were provided for both specimens; 2 the JRA specification slightly overestimated the ultimate strength of both specimens; and 3 neither specifications predicted the observed buckling sequence in Specimen 2. A general-purpose nonlinear finite element analysis program ABAQUS was used to perform correlation study. The analysis showed that the ultimate strength and postbuckling behavior of the specimens could be reliably predicted when both the effects of residual stresses and initial geometric imperfections were considered in the model.
An asymptotic preserving approach for nonlinear Schrodinger equation in the semiclassical limit

We study numerically the semiclassical limit for the nonlinear Schroedinger equation thanks to a modification of the Madelung transform due to E.Grenier. This approach is naturally asymptotic preserving, and allows for the presence of vacuum. Even if the mesh size and the time step do not depend on the Planck constant, we recover the position and current densities in the semiclassical limit, with a numerical rate of convergence in accordance with the theoretical results, before shocks appear in the limiting Euler equation. By using simple projections, the mass and the momentum of the solution are well preserved by the numerical scheme, while the variation of the energy is not negligible numerically. Experiments suggest that beyond the critical time for the Euler equation, Grenier's approach yields smooth but highly oscillatory terms.
Academics and Learners’ Perceptions on Blended Learning as a Strategic Initiative to Improve Student Learning Experience

The increasingly tighter shift of socio-economic constraints on higher education sectors in the recent years has called for greater flexibilities in student learning experience both locally and abroad. To this end, we have recently implemented a Blended Learning Initiative in an attempt to provide better learning support and greater flexibility to our students. This initiative is also in line with the University’s aim of having 50% of our learning and teaching delivered on-line by 2020. In this report, we present our findings on academics and learners’ perceptions on the approach which were obtained through surveys. Results showed that blended learning approach was new to the academics and the factors for successful blended learning implementation were identified. Results also showed that learners appreciated the approach as it made learning more accessible and flexible. Furthermore, they also enjoyed the interesting online activities incorporated into their units. In addition, learners were also able to review and pace their own learning. They also perceived that they have the access to the resources and technical ability to cope with online learning materials and activities. Nonetheless, the survey also revealed that learners still prefer to have academics delivering information to them directly rather than a flipped classroom model. In conclusion, findings from this study provide insights that blended learning could be effective to supplement courses offered by the faculty.
Performance of Broiler Chicken Fed Enzyme Supplemented Cassava Peel Meal Based Diets

3 Abstracts: Eight weeks experiment was conducted to investigate the performance of broiler chicken fed varying levels of enzymes supplemented cassava peel meal (CPM) and its cost benefit. Five experimental diets for broiler starter and finisher diets were formulated in which enzyme supplemented cassava peel meal replace maize at 0, 25, 50, 75 and 100%. One hundred and twenty (120) Anak broiler chicks were randomly allotted to five dietary treatments in a completely randomized design with three replicates containing eight birds. The results of feed intake, feed conversion ratio and daily weight gain however, showed significant difference. Numerical means of the treatment showed slight variation when compared to the control diets. Mortality of 6.66% was recorded during the experimental period. Feed cost per kilogram of feed, cost of feed per kilogram gained also decreases with increasing levels of enzyme supplemented CPM.
Comparison of Bone Mineral Density Levels in Young-adult Patients with Schizophrenia and Healthy Controls

Comparison of bone mineral density levels in young-adult patients with schizophrenia and healthy controls Objective: The aim of this study was to assess bone mineral density levels of patients with schizophrenia and to compare the results with healthy controls. Methods: Fourteen patients with schizophrenia and 31 healthy controls, between 22 and 44 years of age, were enrolled in this cross-sectional study. Bone mineral density (BMD) levels of each group were measured by Dual Energy X-ray Absorbiometry (DEXA). The patients were assessed using the Positive and Negative Symptom Scale (PANSS). All patients had been receiving antipsychotic treatment for at least 2 years. Patients’ sociodemographic caharacteristics and risk factors for osteoporosis (antipsychotic use, sunlight exposure, physical activity, etc.) were documented. Results: As compared with the healthy controls, the patients with schizophrenia had significantly lower BMD at the lumbar spine and at all sites of the proximal femur. Correlation analysis showed that the only factor related with the femoral BMD only in patients with schizophrenia was the age. No association between BMD and gender, PANSS score, type of antipsychotic medications, and other risk factors for osteoporosis were observed. Conclusions: In this study, we found that BMD in schizophrenia patients was lower than that of healthy controls and this finding suggest that osteoporotic changes may be seen in younger ages. Further prospective studies are needed to better clarify the relationship between osteoporosis and schizophrenia.
The Relationship between Service Recovery and Patronage Intentions: The Mediating Role of Relationship Quality

This study aims to investigate, using the structural equation modeling with a partial least square (PLS-SEM) approach, the relationship among service recovery strategies, relationship quality, and customer patronage intentions concerning Internet Service Providers (ISPs) in Egypt. Our findings confirmed that some service recovery strategies positively influence on both relationship quality and patronage intentions. As well as, relationship quality has a significant impact on customer patronage intentions. Furthermore, relationship quality has the role of a mediator of the relationship between SR strategies and patronage intention. Moreover, both speeds of recovery and empathy moderate the relationship between some SR strategies and relationship quality. Finally, our study proposed some theoretical and managerial implications.
A fire model with distinct crop, pasture, and non-agricultural burning: use of new data and a model-fitting algorithm for FINAL.1

Abstract. This study describes and evaluates the Fire Including Natural & Agricultural Lands model (FINAL) which, for the first time, explicitly simulates cropland and pasture management fires separately from non-agricultural fires. The non-agricultural fire module uses empirical relationships to simulate burned area in a quasi-mechanistic framework, similar to past fire modeling efforts, but with a novel optimization method that improves the fidelity of simulated fire patterns to new observational estimates of non-agricultural burning. The agricultural fire components are forced with estimates of cropland and pasture fire seasonality and frequency derived from observational land cover and satellite fire datasets. FINAL accurately simulates the amount, distribution, and seasonal timing of burned cropland and pasture over 2001–2009 (global totals: 0.434×106 and 2.02×106 km2 yr−1 modeled, 0.454×106 and 2.04×106 km2 yr−1 observed), but carbon emissions for cropland and pasture fire are overestimated (global totals: 0.295 and 0.706 PgC yr−1 modeled, 0.194 and 0.538 PgC yr−1 observed). The non-agricultural fire module underestimates global burned area (1.91×106 km2 yr−1 modeled, 2.44×106 km2 yr−1 observed) and carbon emissions (1.14 PgC yr−1 modeled, 1.84 PgC yr−1 observed). The spatial pattern of total burned area and carbon emissions is generally well reproduced across much of sub-Saharan Africa, Brazil, Central Asia, and Australia, whereas the boreal zone sees underestimates. FINAL represents an important step in the development of global fire models, and offers a strategy for fire models to consider human-driven fire regimes on cultivated lands. At the regional scale, simulations would benefit from refinements in the parameterizations and improved optimization datasets. We include an in-depth discussion of the lessons learned from using the Levenberg–Marquardt algorithm in an interactive optimization for a dynamic global vegetation model.
Chapter 3 Pharmacophore based virtual screening of pyridopyridazin-6-ones

p38-α Mitogen activated protein kinase (MAPK) is a serine/threonine kinase activated by environmental stimuli like stress and by various proinflammatory cytokines like tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). Excessive production of TNF-α and IL-1β may lead to various diseases such as rheumatoid arthritis, psoriasis and inflammatory bowel. Hence inhibition of p38-α MAPK can be a novel approach for the development of new anti-inflammatory agents. In this study a combined use of pharmacophore generation, atom based 3D-quantitative structure activity relationship (3D-QSAR), molecular docking and virtual screening has been performed for a series of pyridopyridazin-6-ones exhibiting p38-α MAP kinase inhibition activity. A five point pharmacophore (AAAHR): three hydrogen bond acceptors (AAA), one hydrophobic (H) and one aromatic ring (R) feature was obtained. A statistically significant 3D-QSAR model was obtained using this pharmacophore hypothesis with correlation coefficient (r 2 = 0.91) and high Fisher ratio (F =90.3) for the training set of 47 compounds. Also, the predictive power of generated model was found to be significant which was confirmed by the high value of cross validated correlation coefficient (q 2 = 0.80) and Pearson-R (0.90) for the test set of 16 compounds. Further, docking study revealed the binding orientations of active ligand at active site amino acid residues Val30, Gly31, Lys53, Leu75, Asp88, and Met109 of p38-α MAP kinase. The results of ligand based pharmacophore hypothesis and atom based 3D-QSAR explore the detailed structural insights and also highlights the important binding features of pyridopyridazin-6-ones with p38-α MAP kinase. These findings may provide useful guidelines for rational design of compounds as better p38-α MAP kinase inhibitors. 3.2 Introduction
Decay of Ultrarelativistic Remnant Belt Electrons Through Scattering by Plasmaspheric Hiss

Ultrarelativistic electron remnant belts appear frequently following geomagnetic disturbances and are located in‐between the inner radiation belt and a reforming outer belt. As remnant belts are relatively stable, here we explore the importance of hiss and electromagnetic ion cyclotron waves in controlling the observed decay rates of remnant belt ultrarelativistic electrons in a statistical way. Using measurements from the Van Allen Probes inside the plasmasphere for 25 remnant belt events that occurred between 2012 and 2017 and that are located in the region 2.9
Preferential perpendicular acceleration of heavy ionospheric ions by interactions with electrostatic hydrogen cyclotron waves

The energization of heavy ionospheric ions by electrostatic hydrogen cyclotron (EHC) waves is examined. In particular, the problem of preferential perpendicular acceleration of heavy ions above 5000 km along auroral field lines is examined critically. Observations have indicated that above this altitude the occurrences of ion beams and EHC waves are highly correlated and that the occurrence rates are high. The EHC waves are found to be coherent. The energization process is examined in the light of interactions of a single coherent wave with the ions. The interactions can be stochastic or nonstochastic, depending on the parameters of the wave and of the background H/sup +/ ions supporting the wave. With electric field wave amplitudes of a few tens of mV/m, it is shown that the interaction can give perpendicular energies of the order of keV for O/sup +/ ions. He/sup +/ ions are shown to gain perpendicular energies smaller than O/sup +/ ions. It is indicated that upward flowing H/sup +/ ions cannot gain any appreciable amount of perpendicular energy. For a given electric field wave amplitude E/sub 0/, the extent of energization critically depends on the average perpendicular energy (temperature) W/sub perpendicularB/ of the background H/sup +/ ionmore » plasma. Examples are worked out for values of W/sub perpendicularB/ ranging from 1 to 200 eV. The resulting energizations and pitch angles for O/sup +/ and He/sup +/ ions are compared with observations from satellites. The heating times for the ions are found to be of the order of 2 s at an altitude of 5000 km. « less
Statistical Study of Magnetic Reconnection in the Solar Wind

Magnetic reconnection is a phenomenon where the energy stored in the magnetic eld dissipates into plasma heating and acceleration. It can occur on boundaries connecting plasma with dierent magnetic eld orientations. In spacecraft observations, we can identify magnetic reconnection through its exhaust where the plasma on reconnected eld lines leaves the reconnection site. We present a statistical study of magnetic reconnection in the solar wind based on data from the WIND spacecraft during the period of 1995{2010. We track the signatures of the magnetic reconnection exhaust such as a rotation of the magnetic eld or acceleration and heating of the plasma. We found dependence of the heating and plasma acceleration inside reconnection exhaust.
PENGARUH BELANJA KESEHATAN TERHADAP ANGKA HARAPAN HIDUP KABUPATEN KOTA DI JAWA BARAT

This paper has two objectives. The first is to estimate the effect of health expenditure on life expectancy in regencies and cities in West Java Provinces. The second is to estimate the effect of the number of poor people on life expectancy in regencies and cities in West Java Provinces. Life expectancy is a measurement of the average time of human lives. This paper uses three-technique of Data Panel regression model: Pooled OLS, Fixed Effect Model and Random Effect Model. This paper uses Data Panel on 27 Regencies and Cities in West Java Provinces from 2014 to 2016. This paper use Life expectancy as the dependent variable, health expenditure and number of poor people as the independent variable. The result shows that Pooled OLS, Fixed Effect Model and Random Effect Model estimate the health expenditure has a positive and significant effect on life expectancy in regencies and cities in West Java Provinces. Pooled OLS and Random Effect Model technique estimate number of poor people has a negative and significant effect on life expectancy in regencies and cities in West Java Provinces.