Miracle-dz/UniFAR-FTUs huggingface dataset:
Proteomic Analysis of Arabidopsis pldα1 Mutants Revealed an Important Role of Phospholipase D Alpha 1 in Chloroplast Biogenesis

Phospholipase D alpha 1 (PLDα1) is a phospholipid hydrolyzing enzyme playing multiple regulatory roles in stress responses of plants. Its signaling activity is mediated by phosphatidic acid (PA) production, capacity to bind, and modulate G-protein complexes or by interaction with other proteins. This work presents a quantitative proteomic analysis of two T-DNA insertion pldα1 mutants of Arabidopsis thaliana. Remarkably, PLDα1 knockouts caused differential regulation of many proteins forming protein complexes, while PLDα1 might be required for their stability. Almost one third of differentially abundant proteins (DAPs) in pldα1 mutants are implicated in metabolism and RNA binding. Latter functional class comprises proteins involved in translation, RNA editing, processing, stability, and decay. Many of these proteins, including those regulating chloroplast protein import and protein folding, share common functions in chloroplast biogenesis and leaf variegation. Consistently, pldα1 mutants showed altered level of TIC40 (a major regulator of protein import into chloroplast), differential accumulation of photosynthetic protein complexes and changed chloroplast sizes as revealed by immunoblotting, blue-native electrophoresis, and microscopic analyses, respectively. Our proteomic analysis also revealed that genetic depletion of PLDα1 also affected proteins involved in cell wall architecture, redox homeostasis, and abscisic acid signaling. Taking together, PLDα1 appears as a protein integrating cytosolic and plastidic protein translations, plastid protein degradation, and protein import into chloroplast in order to regulate chloroplast biogenesis in Arabidopsis.
ROLE OF INDONESIAN TEACHERS’ COMPETENCIES IN DEVELOPING CHILD FRIENDLY SCHOOL

This paper is a theoretical discussion about role of teachers’ competencies in developing Child Friendly School (CFS). Teachers is a key factor that influence to education quality of school. Teachers who have four required competencies (pedagogic, professional, social, and personality), it would create the qualified level of education system in school as well. Qualified school itself is a goal of CFS model of the UNICEF. Through their pedagogical competence, teachers are able to recognize students’ potencies, condition, rights and needs, therefore they are able to design effective and appropriate learning as well. The ability of teachers to master science and technology is covered in the professional competence, so as to provide meaningful learning experiences for students. Teacher's ability to communicate and interact well with students, parents, and stakeholders depicted in the social competence of teachers, therefore teachers could address the social issues as well. In addition, the role of the teacher as a good example for the students and creating the motivated atmosphere of learning are in the competence of the teacher's personality. Those four of Indonesian teachers’ competencies have to meet with CFS aspects.
Using Simultaneous Prompting for Teaching Various Discrete Tasks to Students with Mental Retardation

Effectiveness of a simultaneous prompting procedure was evaluated for students with mental retardation at different levels of schools (preschool, primary and secondary grades) using various discrete tasks. Participants included three students whose functioning levels ranged from typically developing to mild and moderate mental disabilities. Effectiveness of a simultaneous prompting procedure was evaluated through use of a multiple probe design across behaviors and replicated across students. Results indicated that the procedure was successful in teaching targeted behaviors to all students. Students maintained target behaviors at high rates up to 7, 18, and 25 weeks after training and generalized responses across people, materials, and settings. Limitations and implications for future research are discussed.
Use of Granulands for Analysis of Social Class

In this paper, an analytical tool enabling the analysis of social stratification is proposed. The classical scheme for scaling consisting of two stages, conceptualisation and operationalization, is modified by the use of the concept of granulation introduced by L. Zadeh. The essential step in the modified scheme for the quantification of vague concepts concerning social class is realized using linguistic variables. The essential part of the methodology presented is illustrated by a simple hypothetical example. However, the methodology is suitable for any classification problem when classes are defined verbally.
Autoantibodies to NR 2 A Peptide of the Glutamate / NMDA Receptor in Patients with Seizure Disorders in Neuropsychiatric Systemic Lupus Erythematosus

1Guangdong No. 2 Provincial People’s Hospital, Courtyard No. 466, Middle Xingang Road, Haizhu District, Guangzhou 510317, China 2Department of Neurology, Nanfang Hospital, Southern Medical University, No. 1838 North Guangzhou Avenue, Guangzhou 510515, China 3TEDA International Cardiovascular Hospital, Medical College, Nankai University, Tianjin, China 4School of Public Health, Southern Medical University, No. 1023 South Shatai Rd., Guangzhou, Guangdong 510515, China 5Department of Histology and Embryology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China 6Nanfang Hospital, Southern Medical University, Guangzhou 510515, China 7Department of Rheumatology, Nanfang Hospital, Southern Medical University, No. 1838 North Guangzhou Avenue, Guangzhou 510515, China
A COMPARATIVE ANALYSIS OF PROTEASE PRODUCING MICROBES ISOLATED FROM TANNERY EFFLUENT

Proteases are well known enzymes for their wide range application in food industry, detergent industry and pharmaceuticals industry for the preparation of ointments and medicine. They are also widely used in leather industry for dehairing and bating of hides as an alternative for toxic chemicals which in turn hamper the environment. As enzymes have proved to solve unresolved technical issues relating to pollution control the present study was undertaken to screen for organisms which could produce extracellular proteases. Organisms were isolated from tannery effluent, in which 13 isolates were obtained and among which 5 isolates were found to produce extracellular proteases. Biochemical test revealed the organisms to be Aeronomas sp. , Alcaligenes sp. , Bacillus sp. , Staphylococcus sp. and Pseudomonas sp. The stability of the protease was also studied under temperature and pH. The organism was found to grow over a wide range of pH and temperatures. Among the 5 isolates Aeronomas sp. , Bacillus sp. , Staphylococcus sp. and Pseudomonas sp. showed enzyme production at pH 8.0 and Alcaligenes sp at pH 9.0. The enzyme production for all the isolates was found to be between 45°C to 65°C with ane optimum temperature of 55°C. Zymography analysis in this present study showed extracellular caseinase activity by substrate hydrolysis.
A Comparative Study of Corporate Image in the Real Estate Industry in the City of Kunming, China

This research aims to investigate the differences in terms of corporate identity, reputation, and corporate image between two real estate developers in the city of Kunming, China. Additionally, the relationship between corporate identity, reputation and corporate image was also tested. The data was collected from 400 respondents by using a non-probability sampling procedure. The research outcomes revealed that there was a difference between these two developers in terms of corporate identity with regard to name, price, and distinctive features, in terms of reputation with respect to credibility, and in terms of corporate image. In contrast, no difference existed in their advertising of corporate identity and reputation with respect to product quality and financial soundness. Moreover, for both developers, a positive relationship between corporate identity, reputation, and corporate image was shown to exist
Does AIDS-Related Mortality Reduce Per-Capita Household Income? Evidence from Rural Zambia

This paper evaluates the effect of AIDS-related mortality on per-capita incomes of surviving household members, using a large nationally representative sample of rural households from Zambia. To minimize selection bias that may arise because AIDS is likely to be the endogenous outcome of individual behavior, we employ a difference-in-difference propensity score matching estimator. We find that the death of a prime-age member has no significant impact on per-capita household income. This result continues to hold when we control for spillover effects by excluding households from the control group if members departed or joined for reasons related to AIDS. A likely explanation for this finding is that surviving household members pursue a mix of income and demographic coping strategies that prevents income losses in the short to medium run.
Predicting Motor Outcomes in Stroke Patients Using Diffusion Spectrum MRI Microstructural Measures

Improved understanding of neuroimaging signal changes and their relation to patient outcomes after ischemic stroke is needed to improve ability to predict motor improvement and make therapy recommendations. The posterior limb of the internal capsule (PLIC) is a hub of afferent and efferent motor signaling and this work proposes new, image-based methods for prognosis based on interhemispheric differences in the PLIC. In this work, nine acute supratentorial ischemic stroke patients with motor impairment received a baseline, 203-direction diffusion brain MRI and a clinical assessment 3–12 days post-stroke and were compared to nine age-matched healthy controls. Asymmetries based on the mean and Kullback-Leibler divergence in the ipsilesional and contralesional PLIC were calculated for diffusion tensor imaging (DTI) and diffusion spectrum imaging (DSI) measures from the baseline MRI. Predictions of upper extremity Fugl-Meyer (FM) scores at 5-weeks follow-up from baseline measures of PLIC asymmetry in diffusion tensor imaging (DTI) and diffusion spectrum imaging (DSI) models were evaluated. For the stroke participants, the baseline asymmetry measures in the PLIC for the orientation dispersion index of the neurite orientation dispersion and density imaging (NODDI) model were highly correlated with upper extremity FM outcomes (r2 = 0.83). Use of DSI and the NODDI orientation dispersion index parameter shows promise of being more predictive of stroke recovery and to help better understand white matter changes in stroke, beyond DTI measures. The new finding that baseline interhemispheric differences in the PLIC calculated from the orientation dispersion index of the NODDI model are highly correlated with upper extremity functional outcomes may lead to improved image-based motor-outcome prediction after middle cerebral artery ischemic stroke.
The link between non-property crime and house prices – Evidence from UK street-level data

This paper uses street-level data on house sales and crime rates for England and Wales to look at the existence of compensating differentials for crime risk. In terms of identification my strategy relies on the use of non-parametric regional time trends as well as various fixed effects to control for unobserved amenities and regional economic conditions. The results suggest that each additional case of anti-social behavior lowers house prices in the same street by approximately 1% and each additional case of violent crime by 2%. Drug crime does not appear to matter, as does crime outside of the respective street.
Dynamic Young’s Modulus of Scarf- and Finger-Jointed Beams using Longitudinal Vibration Method

The elastic properties of oak wood (solid wood, scarf-jointed beams, and finger-jointed beams) and two different, independently applied adhesives (polyvinyl acetate and isocyanate) were investigated. Using a longitudinal vibration technique and comparing the elastic modulus of the solid wood and jointed beams, it was revealed that longer fingers (10 mm) in the finger joints and larger angle joints (70° and 75°) in the scarf-jointed beams enhanced the elastic properties of the beams. Based on these findings, it was concluded that these configurations result in elastic properties that are most similar to those of solid wood. The application of polyvinyl acetate rather than isocyanate significantly (P < 0.05) improved the elastic properties of the joints (both scarf- and finger-jointed beams).
Midwinter Deceleration of the Subtropical Mesospheric Jet and Interannual Variability of the High-Latitude Flow in UKMO Analyses

Abstract The variability of zonally averaged stratospheric circulation is examined using daily gridded analyses from the U.K. Met. Office for 1991–99, corresponding to the period observed by the Upper Atmosphere Research Satellite. Application of rotated principal component analysis to the dataset reveals dominant modes of variability consisting of annual, semiannual, and quasi-biennial oscillations, together with intraseasonal and interannual variability in the winter hemisphere. In the upper stratosphere during northern winter, poleward propagating zonal wind anomalies at the stratopause and a sudden deceleration of the subtropical mesospheric jet in each midwinter are observed. The high-latitude flow is more variable, and the data suggest two contrasting types of wintertime evolution in the polar stratosphere. One is characterized in high latitudes by relatively strong flow in early winter and a significantly weakened flow after solstice, the other by relatively weak flow in early winter and a strong p.
Digital fixation: the law and economics of a fixed e-book price

Fifteen OECD countries, ten of which EU members, have regulation for fixing the price of printed books. At least eight of these have extended such regulation to e-books. This article investigates the cultural and economic arguments as well as the legal context concerning a fixed price for e-books and deals with the question of how the arguments for and against retail price maintenance for e-books should be weighted in the light of the evidence. It concludes that while the evidence in defence of a fixed price for printed books is slim at best, the case for a fixed price for e-books is weaker still while the legal acceptability within EU law is disputable. Against this background, introducing a fixed price for e-books is ill-advised.
Postural balance in subjects over the age of 50

W s t e p . Stabilnośc posturalną powszechnie uznaje sie za jeden z glownych wyznacznikow sprawności funkcjonalnej czlowieka. Zmienia sie ona w czasie ontogenezy, ulegając pogorszeniu w okresie starzenia. Technika posturograficzna daje mozliwośc przeprowadzenia analizy wychwian ciala czlowieka i jest stosowana w celu otrzymania obiektywnych i ilościowych danych o rownowadze posturalnej. Wyniki testow posturograficznych wykonanych u zdrowych osob umozliwiają analize wynikow badan stabilności posturalnej wykonywanych w instytucjach, ktore nie mają mozliwości przebadania osob zdrowych jako grup kontrolnych. M a t e r i a l i m e t o d y . Badaniem objeto 126 zdrowych osob bez stwierdzonych zaburzen neurologicznych i motorycznych w wieku od 50 do 97 lat. Stabilnośc posturalna oceniana byla przy uzyciu zestawu posturograficznego (PROMED – Legionowo), ktory wyznacza wielkośc pola statokinezjogramu, dlugośc statokinezjogramow, amplitudy jednokierunkowych wychylen w plaszczyźnie strzalkowej i plaszczyźnie czolowej oraz parametru „koordynacja”. U kazdej osoby przeprowadzono standardowy zestaw testow skladający sie z badania przy oczach otwartych, przy oczach zamknietych oraz badania kordynacji wzrokowo-ruchowej w teście sprzezenia zwrotnego. Przeprowadzony zostal test ANOVA Kruskala-Wallisa mający na celu określenie wplywu wieku na wartości parametrow posturograficznych. Wy n i k i . W badaniu przy oczach otwartych, zamknietych i w sprzezeniu zwrotnym zaobserwowano wzrost wartości pola statokinezjogramu, dlugości statokinezjogramu, a takze dlugośc stabilogramow w plaszczyźnie czolowej i plaszczyźnie strzalkowej wraz z wiekiem. Wyznaczony w teście sprzezenia zwrotnego parametr kordynacja zmniejszal sie wraz z wiekiem i osiągnąl najnizszą wartośc w grupie osob najstarszych. Test Kruskala-Wallisa wskazal na istotny wplyw wieku na wartości parametrow posturograficznych. Wn i o s k i . Otrzymane wyniki prezentują wartości prawidlowe dla testow posturograficznych prowadzonych u osob powyzej 50. roku zycia. Zaobserwowany systematyczny i znaczny wzrost wartości parametrow pola statokinezjogramu, dlugości statokinezjogramu, dlugości wychylen w plaszczyźnie czolowej i strzalkowej oraz pogorszenie koordynacji wzrokowo-ruchowej u osob powyzej 60. roku zycia podczas stania swobodnego w probie z oczami zamknietymi, otwartymi i koordynacji wzrokowo-ruchowej wskazuje na pogorszenie funkcjonowania mechanizmow kontroli posturalnej. Badanie posturograficzne jest wiec badaniem wlaściwym dla oceny postepującego od szostej dekady zycia oslabienia mechanizmow kontroli posturalnej.
Dynamics of gas formation during ensilage

The formation of a whole spectrum of gasses, which is undesirable occurs during ensiling process. The formation of gasses is undesirable, because it is often a sign of undesirable processes in silages, and causes concern about the impact on the global environment. Formation of CO2 is the most abundant. Besides CO2, the formation of toxic N oxides also occurs during ensiling. Since silage additive addition affects the fermentation pattern, the aim of the study was to monitor the formation of various gasses from silages treated with different silage additives. A grass ley (70% timothy) was harvested on August 24th 2013, nearby Helsingborg. Bacterial inoculant (E. faecium, L. plantarum, L. buchneri) at the rate of 250000 cfu/g FF, and silage additive Safesil at the rate of 3 L/ton FF were compared with untreated control. Gasses collected in bags were analysed for N2, H2, O2, CO, CH4 by gas chromatographaphy. CO2, NO, and NO2 were absorbed in water and analysed using ion chromatography. Standard analyses to determine silage quality were performed after ensiling period. Silages treated with bacterial inoculant had significantly higher pH, propionic acid, acetic acid, and ethanol contents but lower concentration of lactic acid than other silage treatments. Control and bacterially inoculated silages produced more gas than Safesil treated silages, mainly due to an increased proportion of CO2. The formation of NOx gases displayed no significant differences among other treatments.
Group Long-Term Disability Insurance Claims and the Business Cycle

This paper explores the relationship between private group long-term disability (LTD) submitted claims incidence and the business cycle. While much of the recent literature connecting disability incidence to the economy tends to focus on employment conditions, we rigorously explore broader economic connections between the submission of LTD claims and the business cycle. Using a group LTD data set from a private-sector carrier with approximately 104 million records drawn from both the manufacturing and wholesale/retail sectors and data for a carefully chosen set of economic variables, we find statistically-significant relationships between the change in LTD incidence and change in the status of various sectors of the U.S. economy. Our findings, we argue, are consistent with the idea that the submission of LTD claims is influenced not just by employment conditions, but also by current and anticipated future conditions in other economic sectors as well. Our results have important implications for the insurance industry, given the size of the market and the long-term nature of claims payments.
The utilisation of fly ash in CO2 mineral carbonation

The fixation of CO2 in the form of inorganic carbonates, also known as mineral carbonation, is an interesting option for the removal of carbon dioxide from various gas streams. The captured CO2 is reacted with metal-oxide bearing materials, usually naturally occurring minerals. The alkaline industrial waste, such as fly ash can also be considered as a source of calcium or magnesium. In the present study the solubility of fly ash from conventional pulverised hard coal fired boilers, with and without desulphurisation products, and fly ash from lignite fluidised bed combustion, generated by Polish power stations was analysed. The principal objective was to assess the potential of fly ash used as a reactant in the process of mineral carbonation. Experiments were done in a 1 dm3 reactor equipped with a heating jacket and a stirrer. The rate of dissolution in water and in acid solutions was measured at various temperatures (20 – 80oC), waste-to-solvent ratios (1:100 – 1:4) and stirrer speeds (300 – 1100 min-1). Results clearly show that fluidised lignite fly ash has the highest potential for carbonation due to its high content of free CaO and fast kinetics of dissolution, and can be employed in mineral carbonation of CO2.
The Multimodal Perception of Contrastive Focus in French: A Developmental Study

The current study aimed to better understand the development of prosody perception, by investigating the audiovisual, audio, and visual perception of contrastive focus in French-speaking adults and children. Specifically, 20 adults and 20 school-aged children were presented with short sentences in audiovisual, audio, and visual modalities and were asked to determine if the sentences were produced under neutral or contrastive focused speech. Target words incorporated into the sentences varied across four vowels: /i y u a/. Overall, the adults performed significantly better than the children. Moreover, the children relied more on duration cues to identify contrastive focus, while the adults relied more on formant and lip height values. These findings suggest that children acquire visual cues of speech perception as they mature.
The Development of Patientsʼ Perceptions of Pharmacy Service Quality of Highly-Active Antiretroviral Therapy Program (PSQ-HAART) Questionnaire in Chiang Rai Community Hospitals, Thailand

The purpose of this study was to: 1) develop a self-administered written survey for assessing PSQ-HAART in Chiang Rai community hospitals 2) identify distinct constructs of the evaluation items and 3) examine the instrumentsʼ psychometric properties. Three- hundred-and-fifty-four service quality items include 22 from the original 22-item SERVQUAL, added to 319 items from patientsʼ expectations taken from in-depth interviews and 13 items on the pharmacistsʼ role in HIV/AIDS care from literature reviews. These 354 items were first reduced to a 49-item scale, and then two psychometric tests were performed. Psychometric test I was conducted among 320 patients from antiret- roviral (ARV) clinics in four Chiang Rai community hospitals. The first 49-item scale identified underlying dimensions and purified items. Results produced a six-dimensional 36-item scale (tangibles-reliability, assurance-empathy, empathy, responsiveness I, respon- siveness-assurance and responsiveness II) instead of the five dimensions of SERVQUAL (tangibles, reliability, responsiveness, assurance and empathy). Factor loadings ranged from 0.38 to 0.73. The 36-item scale was split into two sections: desired service level and perception of actual service level. This instrument was for Psychometric test II which was conducted a month later among 216 patients from ARV clinics in the other four community hospitals. Final results produced a 33-item scale in six dimensions and exhibited high internal consistency (0.94) of both expectation and perception items. The findings identified several aspects of pharmacy service quality in Thai community hospitals needing improvement. The questionnaire needs to be adapted for use in PSQ-HAART programs in community hospitals throughout the country.