Miracle-dz/UniFAR-FTUs huggingface dataset:
Music Genre Classification by Lyrics using a Hierarchical Attention Network

We adapt the hierarchical attention network for the task of genre classification using lyrics. Utilising a large dataset of intact song lyrics we apply a recurrent neural network model which tries to learn importance of words, lines and sections in the genre classification task. This hierarchical structure attempts to replicate the structure of lyrics and enable learning of which sections, lines or words play importance in different genres. We explore the differences between taking layers at the line level or at the section level. We test the model over a 117 genre dataset and a smaller 20 genre dataset, classifying over a much higher number of genres than previous research. Experiments show that the hierarchical attention network outperforms basic non-neural models and in certain situations simple neural models, although high classification accuracies still present a tough challenge. We visualise the performance of the model by extracting from songs the lines and words it applies most weight to in the classification task.
Vascular Endothelial Growth Factor, Hypoxia-Inducible Factor 1 Alpha and CD34 Expressions in Early-Stage Gastric Tumors: Relationship with Pathological Factors and Prognostic Impact on Survival

Background: Angiogenesis is one of the key steps in solid tumor growth and metastasis. We planned to investigate the prognostic significance of vascular endothelial growth factor (VEGF), hypoxia-inducible factor 1α (HIF-1α) and CD34 expressions as markers of angiogenesis in gastric cancer. Patients and Methods: We retrospectively reviewed the medical records of 51 gastric cancer patients who had total or subtotal gastrectomy at Marmara University Hospital from 1990 to 2004 and evaluated the expression of VEGF, HIF-1α and CD34 by immunohistochemistry in their archival tumor tissues. We recorded the clinical and pathological characteristics of these patients and analyzed their survival outcome. Results: Thirty out of 51 patients were males. The median age was 63 years (range 34–81). The median follow-up was 17 months. Thirty-six patients had node-positive disease. The majority of patients (n = 43) had T2 and T3 disease. Vascular and lymphatic invasions were present in 57 and 77% of tumors, respectively. VEGF and HIF-1α were positive in 65 and 71% of tumors. The median CD34 staining score was 19 (3–68). VEGF, HIF-1α and CD34 expressions were more frequent in tumors without serosal invasion (p = 0.01, p = 0.01 and p = 0.003, respectively). CD34 expression was significantly more frequent in tumors with VEGF and HIF-1α expression (p = 0.00, p = 0.00). HIF-1α expression was more frequent in tumors with VEGF expression (p = 0.00). The 5-year overall survival was 45%. VEGF, HIF-1α, CD34 expressions and other pathological characteristics were found to have no impact on survival. Conclusion: VEGF, HIF-1α and CD34 expressions were more common in tumors without serosal invasion. As a future perspective, biological agents targeting VEGF and HIF-1α might be more effective at earlier stages of gastric cancer.
Influence of Concurrent Tasks on Gait: A Dual-Task Approach

We studied the effect of concurrent tasks on motor control of gait with dual-task methodology. Ten healthy subjects were instructed to perform different cognitive and motor tasks during gait on a conductive walkway. Footswitch signals were recorded and stride time and double-support time were calculated. It was assumed that the former reflects gait-patterning mechanisms and the latter relates to balance control. Statistical analysis showed an increase in double-support time when a memory-retention task (digit-span) and a fine motor task (buttoning) were executed simultaneously during gait. During gait performance of the cognitive task declined compared to baseline conditions. Attentional demand of concurrent cognitive and motor tasks appeared to force subjects to modulate their gait strategy to ensure control of balance. Stride time was consistent across task conditions except when subjects performed fast finger-tapping during gait. Then all but one subject showed a decrease in stride time and an increase in stride-frequency that was repeatable on retest. Since different rhythmic movements are likely to share common neurobiological networks, we assumed that the modulation of stride-frequency was due to structural interference.
Are the hosts of gamma-ray bursts sub-luminous and blue galaxies?

We present K-band imaging observations of ten gamma-ray burst (GRB) host galaxies for which an optical and/or radio afterglow associated with the GRB event was clearly identified. Data were obtained with the Very Large Telescope and New Technology Telescope at ESO (Chile), and with the Gemini-North telescope at Mauna Kea (Hawaii). Adding to our sample nine other GRB hosts with K-band photometry and determined redshifts published in the literature, we compare their observed and absolute K magnitudes as well as their R K colours with those of other distant sources detected in various optical, near- infrared, mid-infrared and submillimeter deep surveys. We find that the GRB host galaxies, most of them lying at 0:5< z< 1:5, exhibit very blue colours, comparable to those of the faint blue star-forming sources at high redshift. They are sub-luminous in the K-band, suggesting a low stellar mass content. We do not find any GRB hosts harbouring R -a ndK-band properties similar to those characterizing the luminous infrared/submillimeter sources and the extremely red starbursts. Should GRBs be regarded as an unbiased probe of star-forming activity, this lack of luminous and/or reddened objects among the GRB host sample might reveal that the detection of GRB optical afterglows is likely biased toward unobscured galaxies. It would moreover support the idea that a large fraction of the optically-dark GRBs occur within dust-enshrouded regions of star formation. On the other hand, our result might also simply reflect intrinsic properties of GRB host galaxies experiencing a first episode of very massive star formation and characterized by a rather weak underlying stellar population. Finally, we compute the absolute B magnitudes for the whole sample of GRB host galaxies with known redshifts and detected at optical wavelengths. We find that the latter appear statistically even less luminous than the faint blue sources which mostly contributed to the B-band light emitted at high redshift. This indicates that the formation of GRBs could be favoured in particular systems with very low luminosities and, therefore, low metallicities. Such an intrinsic bias toward metal-poor environments would be actually consistent with what can be expected from the currently-favoured scenario of the "collapsar". The forthcoming launch of the SWIFT mission at the end of 2003 will provide a dramatic increase of the number of GRB-selected sources. A detailed study of the chemical composition of the gas within this sample of galaxies will thus allow us to further analyse the potential eect of metallicity in the formation of GRB events.
Ureteral Stents Are Associated With Reduced Risk of Ureteral Complications After Kidney Transplantation: A Large Single Center Experience

Background. Controversy exists regarding the benefit of ureteral stents in kidney transplantation. We aimed to examine the association of stents with risk of ureteral complications, particularly in relationship with donor type. Methods. Kidney transplants from 2005 to 2009 were evaluated (n=1224). Patients with previous or simultaneous nonkidney transplants, death, or lost to follow-up within 90 days were excluded, unless already developed a ureteral complication. Only cases with a single extravesical ureteroneocystostomy were included. The cohort (n=961) was divided into stent (32.2%) and no-stent (67.7%) groups. Poisson regression was used to examine the association of stent with ureteral complications (leak or stricture) and urinary tract infections (UTI). Results. Ureteral complication rate was 1.9% in stent versus 5.8% in no-stent group (P=0.007). UTI rate was 14.2% with stent versus 7.9% without stent (P=0.003). Stent use was independently associated with reduction in ureteral complications (incidence rate ratios [IRR], 0.40; P=0.04; 95% confidence interval [CI], 0.17–0.96) and an increase in UTI risk (IRR, 1.79; P=0.006; 95% CI, 1.18–2.74). Stent protective effect was primarily related to reduction in stricture risk (IRR, 0.23; P<0.05; 95% CI, 0.05–0.99). Stents were associated with a decrease in ureteral complications in deceased donor recipients (IRR, 0.34; P=0.03; 95% CI, 0.13–0.88), but not living donors (IRR, 1.24; P=0.84; 95% CI, 0.15–10.2). Conclusions. Ureteral stents are associated with a significant reduction in ureteral complications but increases UTI risk. Routine stenting in deceased donor transplants is recommended as its protective effect was observed in this group. The value of stents in living donor transplants warrants further investigation.
Identification of A New Gene Responsible for the Oxygen Tolerance in Aerobic Life of Streptococcus mutans

Alkyl hydroperoxide reductase in Streptococcus mutans consists of two components, Nox-1 and AhpC. Deletion of nox-1 and ahpC in a double mutant as well as the wild-type of Streptococcus mutans can form colonies in the presence of air to the same extent. The evidence suggested the presence of some other antioxidant system(s) independent of the Nox-1/AhpC system in the bacterium. Here we identified a new antioxidant gene (dpr) and the gene product (Dpr) which complements the defect of peroxidase activity caused by the deletion of nox-1 and ahpC in S. mutans. The dpr-disruption mutant of S. mutans could form colonies anaerobically but not aerobically.
Direct numerical simulation of polymer flow

A device for enabling attachment of a shoplifting detection tag to an article to be protected includes a first attachment rod having an eyelet at one end, a center portion having a bend, and a straight portion at the opposite end from the eyelet suitable for insertion into a clutch mechanism of a shoplifting detection tag; and a second attachment rod having an eyelet at one end, a center portion having a bend, and a straight portion at the opposite end from the eyelet. The first and second attachment rods and the eyelets thereof are of such relative dimensions that the first and second attachment rods may be fitted together to encompass a portion of the article to be protected by passing the straight portion of the first rod through the eyelet of the second rod and by passing the straight portion of the second rod through the eyelet of the first rod, while allowing the straight portion of the first rod to be inserted into the clutch mechanism of the shoplifting detection tag. The attachment rods are made from steel rods that are hardened so as not to be cuttable with hand tools.
POSOP Routing Algorithm: A DTN Routing Scheme for Information Connectivity of Health Centres in Hilly State of North India

We explore the application of partitioned network for providing health services in difficult terrain where fixed communication infrastructure is not cost-effective due to low population density and very high cost of setting up a permanent infrastructure. We propose a hybrid routing which is persistent, on-demand, scheduled, opportunistic, and predicted (POSOP) routing algorithm, that exploits various types of contacts existing in a partitioned, hybrid, and sparse network. Such networks may be used to provide guidance from specialist doctors to junior doctors working in primary health centres. We present a scenario from Uttarakhand (a state in hilly region of North India), where POSOP routing algorithm may be used to provide improved health services. Using simulations, we evaluate the performance of POSOP routing algorithm on three metrics, messages delivered, average delay suffered by the delivered messages, and average message traffic. We compare the performance of POSOP routing algorithm with two routing schemes, namely, epidemic and spray and wait on the three metrics. Our approach outperforms both the routing schemes.
THE PATHOLOGIC ANATOMY OF DEUTERIUM INTOXICATION.

Results are presented of investigations into the nature of the anatomic changes produced upon replacement of one third or more of the total body water of a mouse with heavy water. Microscopic findings included focal renal tubular necrosis, profound alterations in testicular architecture and cellular morphology, and abnormalities of the excretory ducts of the salivary glands.
Impact of Sequential Culture Results on Diagnosis and De-Escalation of the Antibiotic Regimen in Joint and Bone Infections.

BACKGROUND According to existing guidelines, orthopedic specimens collected in joint and bone infections (JBI) in our institution are cultured on several media sets and incubated for two, seven, and 14 days. The optimal timing for de-escalation of the first-line antibiotic combination according to the culture results needs to be defined. METHODS Single-center, retrospective analysis of all adult patients with a first documented episode of JBI between May 2012 and April 2013. RESULTS Ninety patients were included, 51 males (57%), median age 58 y (range 18-87 y), with prosthesis infection in 62 cases (69%). Rapidly growing pathogens (Staphylococcus aureus [n = 36] and Enterobacteriaceae [n = 12]) usually were diagnosed within two days, whereas coagulase-negative staphylococci (n = 25) and Propionibacterium acnes (n = 13) generally were identified after seven days (p < 10-5). Positive culture results at day 2 fit with definitive microbiological diagnosis in 95% of cases, and prolonged incubation led to the identification of additional micro-organisms in only four of 76 patients (5%) with day-2-positive cultures. Conversely, for those with negative two-day culture (n = 14), the seven-day culture allowed identification of less virulent pathogens in eight cases (57%). CONCLUSIONS Our results suggest that, in JBI, de-escalation of the empirical antibiotic regimen can be based on micro-organisms identified on the two-day culture set. The impact of such a strategy on clinical outcomes, antibiotic consumption, and costs needs to be assessed in larger studies.
The C Terminus of the Nuclear RAN/TC4 GTPase Stabilizes the GDP-bound State and Mediates Interactions with RCC1, RAN-GAP, and HTF9A/RANBP1 (*)

Ran/TC4 is a member of the Ras superfamily of GTPases. It is unusual in being predominantly nuclear and because it possesses an acidic -DEDDDL sequence instead of a consensus prenylation domain at the C terminus. Ran is required for nuclear protein import and cell cycle progression, and has been implicated in mRNA processing and export and DNA replication. The inhibition of cell cycle progression by a dominant gain-of-function mutant of Ran has been shown to be abrogated by removal of the -DEDDDL sequence, suggesting that this domain is essential for Ran function. We demonstrate here that the -DEDDDL sequence stabilizes GDP binding to Ran, and that the domain is required for high affinity interaction with a Ran-binding protein, HTF9A/RanBP1. HTF9A functions as a co-stimulator of Ran-GAP (GTPase activating protein) activity on wild-type Ran, but in the absence of the acidic C terminus of Ran, HTF9A behaves as a Ran-GAP inhibitor. An antibody directed against the C-terminal region preferentially recognizes the GTP-bound form of Ran, suggesting that this domain undergoes a nucleotide-dependent conformational change. The results suggest that the acidic C-terminal domain is important in modulating the interaction of Ran with regulatory factors, and implicate Ran-binding proteins in mediating the effects of Ran on cell cycle progression.
Bone Marrow–Derived Kruppel-Like Factor 10 Controls Reendothelialization in Response to Arterial Injury

Objective—The objective of this study was to investigate the role of Kruppel-like factor (KLF) 10, a zinc-finger transcription factor, in bone marrow (BM)–derived cell responses to arterial endothelial injury. Accumulating evidence indicates that BM-derived progenitors are recruited to sites of vascular injury and contribute to endothelial repair. Approach and Results—In response to carotid artery endothelial denudation, KLF10 mRNA expression was markedly increased in both BM and circulating lin− progenitor cells. To examine the specific role of KLF10 in arterial reendothelialization, we used 2 models of endothelial denudation (wire- and thermal-induced injury) of the carotid artery in wild-type (WT) and KLF10−/− mice. WT mice displayed higher areas of reendothelialization compared with KLF10−/− mice after endothelial injury using either method. BM transplant studies revealed that reconstitution of KLF10−/− mice with WT BM fully rescued the defect in reendothelialization and increased lin−CD34+kinase insert domain receptor+ progenitors in the blood and injured carotid arteries. Conversely, reconstitution of WT mice with KLF10−/− BM recapitulated the defects in reendothelialization and peripheral cell progenitors. The media from cultured KLF10–/– BM progenitors was markedly inefficient in promoting endothelial cell growth and migration compared with the media from WT progenitors, indicative of defective paracrine trophic effects from KLF10–/– BM progenitors. Finally, BM-derived KLF10−/− lin− progenitors from reconstituted mice had reduced CXC-chemokine receptor 4 expression and impaired migratory responses. Conclusions—Collectively, these observations demonstrate a protective role for BM-derived KLF10 in paracrine and homing responses important for arterial endothelial injury and highlight KLF10 as a possible therapeutic target to promote endothelial repair in vascular disease states.
RANDOMIZED TRIAL OF TACROLIMUS PLUS MYCOPHENOLATE MOFETIL OR AZATHIOPRINE VERSUS CYCLOSPORINE ORAL SOLUTION (MODIFIED) PLUS MYCOPHENOLATE MOFETIL AFTER CADAVERIC KIDNEY TRANSPLANTATION: RESULTS AT 2 YEARS1

Background. A previous report described the 1-year results of a prospective, randomized trial designed to investigate the optimal combination of immunosuppressants in kidney transplantation. Recipients of first cadaveric kidney allografts were treated with tacrolimus+mycophenolate mofetil (MMF), cyclosporine oral solution (modified) (CsA)+MMF, or tacrolimus+azathioprine (AZA). Results at 1 year revealed that optimal efficacy and safety were achieved with a regimen containing tacrolimus+MMF. The present report describes results at 2 years. Methods. Two hundred twenty-three recipients of first cadaveric kidney allografts were randomized to receive tacrolimus+MMF, CsA+MMF, or tacrolimus+AZA. All regimens contained corticosteroids, and antibody induction was used only in patients who experienced delayed graft function. Patients were followed up for 2 years. Results. The results at 2 years corroborate and extend the findings of the previous report. Patients randomized to either treatment arm containing tacrolimus experienced improved kidney function. New-onset insulin dependence remained in four, three, and four patients in the tacrolimus+MMF, CsA+MMF, and tacrolimus+AZA treatment arms, respectively. Furthermore, patients with delayed graft function/acute tubular necrosis who were treated with tacrolimus+MMF experienced a 23% increase in allograft survival compared with patients receiving CsA+MMF (P =0.06). Patients randomized to tacrolimus+MMF received significantly lower doses of MMF compared with those administered CsA+MMF. Conclusions. All three immunosuppressive regi-mens provided excellent safety and efficacy. How-ever, the best results overall were achieved with tacrolimus+MMF. The combination may provide particular benefit to kidney allograft recipients who develop delayed graft function/acute tubular necrosis. Renal function at 2 years was better in the tacrolimus treatment groups compared with the CsA group.
Bone Marrow Involvement in Non Hematological Disorders – An Institutional Experience

Objective: To find out the frequency of involvement of bone marrow by non – haematological disorders in our institution and to evaluate the role of bone marrow aspiration and biopsy in diagnosing these disorders. Materials & Methods: It was a retrospective study that extended from January 2013 to December 2016. A total of 339 bone marrow aspirates and trephine biopsies were performed during this period. Only the non haematological disorders were studied and their clinical and laboratory parameters were recorded . Peripheral blood picture was studied. Bone marrow aspiration smears & biopsies were evaluated. Results: During the study period, 29 patients were diagnosed to have nonhaematological disorders which constituted 8.5% of the total patients who had undergone bone marrow examination. The age of patients at time of procedure ranged from 3 years to 84years, with male to female ratio of 2.2 :1. Anemia was the most frequent clinical finding followed by fever and weight loss. In adults, metastatic tumors were the commonest non hematological condition diagnosed on bone marrow examination. In children also, metastatic tumors were the commonest non-hematological disease. Conclusion: Metastatic solid tumors were the frequent non-hematologic disorders involving bone marrow in both adults and pediatric patients . Hence, bone marrow examination can be a safe, easy and useful laboratory tool in the diagnosis of various metastatic malignancies and other disorders like granulomatous lesions.
Applications of atomistic calculations to chemical gas sensing

Today, atomistic simulations can be applied to models (containing thousands of atoms) which are very close to real nanotechnology experiments. By combining both theory and experiment it is possible to reach unprecedented insight in applied fields such as chemical sensing. We present two practical cases in which deep insight in the materials properties, sensing mechanisms and optimum operation conditions was achieved thanks to complementing experimental techniques with first-principles simulations. First, we will show how simulations can clarify the sensing mechanisms in the detection of NO2 and NO with SnO2. Second, we will present how changes in the surface of metal oxides due to varying real operation conditions can be determined by combining simulations with luminescence techniques.
Air entrainment processes in a full-scale rectangular dropshaft at large flows

Rectangular dropshafts, commonly used in sewers and storm water systems, are characterized by significant flow aeration. New detailed air–water flow measurements were conducted in a near-full-scale dropshaft at large discharges. In the shaft pool and outflow channel, the results demonstrated the complexity of different competitive air entrainment mechanisms. Bubble size measurements showed a broad range of entrained bubble sizes. Analysis of streamwise distributions of bubbles suggested further some clustering process in the bubbly flow although, in the outflow channel, bubble chords were in average smaller than in the shaft pool. A robust hydrophone was tested to measure bubble acoustic spectra and to assess its field application potential. The acoustic results characterized accurately the order of magnitude of entrained bubble sizes, but the transformation from acoustic frequencies to bubble radii did not predict correctly the probability distribution functions of bubble sizes
No first night shift effect observed following a nocturnal main sleep and a prophylactic 1-h afternoon nap

ABSTRACT Neurobehavioural impairment on the first night shift is often greater than on subsequent night shifts due to extended wakefulness. The aim of the study was to determine whether a 1-h afternoon nap prior to the first night shift is sufficient to produce neurobehavioural performance at levels comparable to the second night shift. Twelve male volunteers (mean age 22.9 years) participated in a laboratory protocol that simulated two 12-h night shifts. A nap preceded the first shift and a 7-h daytime sleep was scheduled between shifts. Neurobehavioural performance and subjective sleepiness measured across each night did not significantly differ between first and second shifts.