Miracle-dz/UniFAR-FTUs huggingface dataset:
Mise en évidence des effets du génotype, de l'agressivité et de l'hygiène sur la teneur en composés odorants du gras dorsal de la viande de porc mâle entier

Les defauts d’odeurs, lies a l’accumulation d’androstenone et de scatol dans le tissu adipeux, sont le frein majeur a l’elevage des porcs mâles entiers. L’androstenone est produite par les testicules et le scatol dans le colon. En dehors de la genetique et de l’alimentation, les facteurs de variation ont ete peu etudies.La these aborde le probleme des odeurs sexuelles sous quatre angles : 1) estimer l’heritabilite des composes odorants du tissu gras et leurs correlations genetiques avec des indicateurs de sante, du developpement sexuel et de l’agressivite ; 2) etudier l’effet de la dominance sur ces composes ; 3) determiner l’impact d’un etat inflammatoire chronique modere sur le developpement sexuel et la concentration en androstenone ; 4) rechercher les effets de conditions d’hygiene contrastees sur la teneur en scatol et analyser l’implication du microbiote intestinalNos resultats confirment l’heritabilite forte des teneurs en composes odorants mais les correlations genetiques avec les parametres de sante sont faibles. Une selection pour reduire la concentration plasmatique en œstradiol et testosterone permettrait de reduire a la fois les teneurs en composes odorants et l’agressivite des porcs. Les porcs de rang de dominance eleve ont une teneur en androstenone superieure dans le gras. Un etat inflammatoire chronique modere ne semble pas affecter la teneur en androstenone. Enfin, la degradation de l’hygiene du logement augmente fortement la concentration en scatol, probablement via des changements de composition du microbiote intestinal.
Atlas e livro vermelho dos briófitos ameaçados de Portugal = Atlas and red data book of threatened bryophytes of Portugal

A brioflora de Portugal Continental integra um total de 704 taxa (incluindo especies, subespecies e algumas variedades consideradas taxonomicamente importantes). Compreende cerca de 40% das especies europeias e quase 65% de todos os briofitos ibericos sendo estes organismos indicados como um dos grupos de plantas mais antigo, com grande importância ecologica, fundamentais para a manutencao da biodiversidade dos ecossistemas. Sao tambem importantes bioindicadores da qualidade ambiental. A presente publicacao foi desenvolvida com suporte no conhecimento da brioflora do pais desde as primeiras colheitas no seculo XIX ate aos estudos mais recentes, adoptando criterios e categorias de ameaca propostas pela UICN (IUCN). Para diversas especies consideradas relevantes e apresentada uma descricao sumaria, os dados de ocorrencia, a ecologia e distribuicao geral, o estado de conservacao e sensibilidade no pais, um mapa de distribuicao, imagens da especie ou habitat, anotacoes e bibliografia. Este livro contempla ainda a Lista Vermelha actualizada, onde para todas as especies conhecidas no pais e indicado o seu estatuto de conservacao. Neste Livro sao tambem identificadas areas prioritarias e propostas medidas especificas para a preservacao das especies, alem de informacao relativa as comunidades de briofitos com elevado estatuto na Rede Nacional de Areas Protegidas.
Comparison of Misoprostol versus Dinoprostone for pre-induction cervical ripening at-term.

BACKGROUND The purpose of this study was to compare the efficacy and safety of 25 μg Misoprostol vs. 0.5 mg Dinoprostone for pre-labour ripening of the cervix at-term. METHODS Nullipara or Para one women with unfavourable cervices after 37 completed weeks with live foetuses were randomized to received either 25 μg intravaginal Misoprostol or 0.5 mg intracervical Dinoprostone. The doses were repeated after 6 hrs if the Bishop Score was less than 6. In cases, in which cervical ripening was not reached even after two doses of ripening agents, oxytocin induction was started at least 6 hours apart. Insertion delivery interval (IDI), complications and pregnancy outcome associated with the use of drugs were compared. RESULTS Two hundred women--100 in each group were evaluated. Comparatively more women (62% vs. 58%) in the Misoprostol group achieved cervical ripening (BS≥6) after one dose. The mean IDI was significantly shorter (3.91 hrs) in the Misoprostol group. The difference was marked more among the multipara at 5.72 hrs, mean difference (p=0.045). In the Misoprostol group 76.92% delivered within 24 hrs whereas, only 70.4% in the Dinoprostone group. Vaginal deliveries were achieved more in the Misoprostol group (78% vs. 71%). No significant differences found in terms of intrapartum complications and foetal outcome. Meconium stained liquor was found more in the Dinoprostone group (23% vs. 32%). CONCLUSIONS A 25 μg dose of Misoprostol is superior in promoting cervical ripening, significantly shortened the insertion delivery interval. It is safe and effective for cervical ripening when applied in the hospital setting with close monitoring.
Clinicopathologic features and treatment outcome of non-Hodgkin lymphoma of the breast – a review of 42 primary and secondary cases in Taiwanese patients

Breast lymphoma is a rare form of non-Hodgkin lymphoma (NHL). However, its clinicopathologic features, treatment, patterns of failure and prognosis remains unclear. We reviewed the clinicopathologic features, treatment variables, failure patterns and the clinical outcome of all cases of breast NHL diagnosed in three institutions in Taiwan between 1984 and 2006. The diagnosis, based on the criteria proposed by Wiseman and Liao, was primary breast lymphoma (PBL) in 23 patients and secondary breast lymphoma (SBL) in 19. Diffuse large B-cell lymphoma was the predominant histological type of both. Among patients with PBL, 18 received chemotherapy and radiotherapy, 3 received chemotherapy alone and 2 received radiotherapy alone. In contrast, all 19 patients with SBL received chemotherapy alone. At a median follow-up of 4.4 years, patients with PBL had a significantly better 5-year event-free survival and overall survival. The contralateral breast was the predominant site of recurrence for patients with PBL. In multivariate analyses, young age and stage IIE disease were significantly associated with poorer prognosis of PBL. Our results indicate combined modality treatment results in a favourable outcome for patients with PBL. Further investigation of underlying mechanisms of young age- and stage IIE disease-related poor prognosis in patients with PBL is needed.
Pressor doses of angiotensin II increase insulin-mediated glucose uptake in normotensive men.

The effect of pressor doses of angiotensin II infused intravenously on insulin-mediated glucose uptake was determined in normotensive men. A 3-h hyperinsulinemic euglycemic clamp was employed in 14 normotensive subjects to determine insulin-mediated glucose uptake with or without an infusion of angiotensin II (approximately 15 ng.kg-1.min-1), which increased blood pressure by 20/15 mmHg (systolic/diastolic). Addition of angiotensin II increased whole body glucose uptake by 15% (9.2 +/- 0.5 vs. 10.8 +/- 0.8 mg.kg-1 x min-1; P = 0.011), and glucose oxidation (determined by indirect calorimetry) by 25% (4.0 +/- 0.3 vs. 4.9 +/- 0.4 mg.kg-1 x min-1; P < 0.05) over insulin alone. There was no significant increase in hepatic glucose output during angiotensin II infusion (2.2 +/- 0.1 vs. 2.4 +/- 0.1 mg.kg-1 x min-1; P = NS). We conclude that angiotensin II in pressor doses increases insulin-mediated glucose disposal and oxidation. The mechanism for this may involve a redirection of blood flow into skeletal muscle during angiotensin II infusion or a direct biochemical action of angiotensin II. Although performed in lean normotensive subjects, these results cast doubt on a significant role for angiotensin II in the insulin resistance associated with essential hypertension.
Zoledronic acid for treatment of Paget's disease of bone

Paget's disease of bone is characterised by a focal increase in bone resorption and bone formation. This anarchic metabolism leads to disorganised bone, with bone pain, fragility, deformity and compression of the peripheral or CNS according to the involved site. Quality of life of sufferers is dramatically impaired. Symptomatic therapy trends to relieve pain, but cannot seek to prevent other complications. Only ‘specific’ therapy can fulfil this purpose. Bisphosphonates have become the cornerstone for therapy of Paget's disease in the last 25 years. Progressively stronger bisphosphonates have been launched on the market. The last drug available, zoledronic acid, the most potent of this drug family, can be administered intravenously. It possesses a long-acting efficacy, allowing a follow up on a yearly basis and permitting the chance of a very long remission of the Pagetic lesion. In the long term, prevention of severe complications can be envisaged, with a reasonable pharmacoeconomic cost.
Developmental Differences in Spinal Cyclooxygenase 1 Expression after Surgical Incision

Background: Systemic administration of a cyclooxygenase 1 (COX-1) inhibitor reduces hypersensitivity to mechanical stimuli after incisional paw surgery in 4-week-old, but not 2-week-old, animals. The purpose of the current study was to test whether this developmental difference was reflected by differences in COX-1 expression in the spinal cord after surgery. Methods: Rats 2 and 4 weeks of age, paralleling infant and child human neurologic developmental stages, were used. A paw incision was made under general anesthesia and the withdrawal thresholds were measured before and after systemic and intrathecal administration of a COX-1 selective inhibitor (SC560). Immunohistochemistry was used to assess COX-1 protein in the spinal cord, and real-time polymerase chain reaction was used to quantify gene expression of COX-1 mRNA. Results: Systemic and intrathecal administration of SC560 produced an increase in withdrawal threshold in the 4-week-old, but not in the 2-week-old, animals. Intrathecal SC560 increased withdrawal thresholds in the 4-week-old animals at a dose 100-fold less than with systemic administration. Cyclooxygenase 1 protein in the spinal cord was increased ipsilateral to surgery in the 4-week-old, but not in the 2-week-old, animals. Cyclooxygenase 1 mRNA was increased in the 4-week-old animals in the spinal cord ipsilateral to surgery relative to the contralateral side of the spinal cord, but not in the 2-week-old animals. Conclusions: These results suggest that developmental differences in COX-1 expression in the spinal cord likely explain the lack of efficacy of COX-1 inhibitors in the 2-week-old rats. Whether this reflects a deficit in factors that stimulate COX-1 expression or a difference in response to these factors is not addressed, but should similar deficits occur in humans, COX-1 inhibitors may exhibit reduced efficacy in infants.
A Randomized, 3-Phase, 34-Week, Double-Blind, Long-Term Efficacy Study of Osmotic-Release Oral System-Methylphenidate in Adults With Attention-Deficit/Hyperactivity Disorder

We conducted a 3-phase, double-blind, placebo-controlled, parallel study design of osmotic-release oral system (OROS)-methylphenidate (MPH) in adults (19-60 years of age) with attention deficit/hyperactivity disorder as classified by the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Phase 1 of the study was a 6-week, acute efficacy trial (n = 223), phase 2 was a 24-week, double-blind continuation study of responders (n = 96), and phase 3 was a double-blind, placebo-controlled, 4-week discontinuation study (n = 23). The mean daily dosage at phase 1 endpoint was 78.4 ± 31.7 mg (0.97 ± 0.32 mg/kg) OROS-MPH and 96.6 ± 26.5 mg (1.16 ± 0.19 mg/kg) placebo (P < 0.0001). Clinical response at phase 1 endpoint was significantly greater in the OROS-MPH group (62%, n = 67 vs 37%, n = 41; P < 0.001) and was maintained throughout 24 weeks of double-blind treatment. With double-blind, placebo-controlled discontinuation, however, there was no statistically significant difference in the rate of relapse between OROS-MPH responders randomized to placebo and those randomized to continue active treatment (18%, n = 2 vs 0%, n = 0; P = 0.1). As expected, decreased appetite, insomnia, being tense/jittery, mucosal dryness, and neurological symptoms were statistically significantly associated with OROS-MPH treatment. More work is needed to be conducted with larger samples being followed to study completion to better understand the long-lasting impact of pharmacotherapy for adult attention-deficit/hyperactivity disorder.
Magnetohydrodynamic implosion symmetry and suppression of Richtmyer-Meshkov instability in an octahedrally symmetric field

We present numerical simulations of ideal magnetohydrodynamics showing suppression of the Richtmyer-Meshkov instability in spherical implosions in the presence of an octahedrally symmetric magnetic field. This field configuration is of interest owing to its high degree of spherical symmetry in comparison with previously considered dihedrally symmetric fields. The simulations indicate that the octahedral field suppresses the instability comparably to the other previously considered candidate fields for light-heavy interface accelerations while retaining a highly symmetric underlying flow even at high field strengths. With this field, there is a reduction in the root-mean-square perturbation amplitude of up to approximately 50% at representative time under the strongest field tested while maintaining a homogeneous suppression pattern compared to the other candidate fields.
5. Obtaining Witness Statements: The Psychology, Best Practice and Proposals for Innovation

McAllister H. , Dale R. and Keay C. (1993) Effects of line-up modality on witness credibility. J. Social Psychol. 133,365-76. McGehee F. (1937) The reliability of the identification of the human voice. J. General Psychol. 17, 249-71. McGehee F. (1944) An experimental investigation of voice recognition. J. General Psychol. 31, 53-65. Orchard T. and Yarmey AD. (1995) The effects of whispers, voice-sample duration and voice distinctiveness on criminal speaker identification. Applied Cognitive Psychol. 9, 249-60. Papcun C. , Kreiman J. and Davis A (1989) Longterm memory for unfamiliar voices. J. Acoustical Society ofAmerica 85, 913-25. Rathborn H. , Bull R. and Clifford B.R. (1981) Voice recognition over the telephone. J. Police Sci. & Admin. 9, 280-4. Read D. and Craik F. (1995) Earwitness identification: some influences on voice recognition. J. Experimental Psychol: Applied 1, 6-18. Reich A and Duke J. (1979) Effects of selected vocal disguises upon speaker identification by listeners. J. Acoustical Society ofAmerica 66, 1023-8. Roebuck R. and Wilding J. (1993) Effects of vowel variety and sample length on identification of a speaker in a line-up. Applied Cognitive Psychol. 7, 475-81. Saslove H. and Yarmey A (1980) Long-term auditory memory: speaker identification. J. Applied Psychol. 65, 111-16. Wallendael L. , Surace A, Parsons D. and Brown M. (1994) Earwitness voice recognition: factors affecting accuracy and impact on jurors. Applied Cognitive Psychol. 8,661-77. Winograd E. , Kerr N. and Spence M. (1984) Voice recognition: effect of orienting task, and a test of blind versus sighted listeners. Am. J. Psychol. 97, 57-70. Yarmey AD. (1991) Voice identification over the telephone. J. Applied Social Psychol. 21, 1868-76. Yarmey AD. (1995a) Earwitness and evidence obtained by other senses. In: Bull R. and Carson D. (eds) Handbook of Psychology in Legal Contexts. Chichester, Wiley. Yarmey AD. (1995b) Earwitness speaker identification. Psychol. Public Policy & Law 1, 792-816. Yarmey AD. and Matthys E. (1992) Voice identification of an abductor. Applied Cognitive Psychol. 6, 367-77. Yarmey AD. , Yarmey L. and Yarmey M. (1994) Face and voice identifications in show-ups and lineups. Applied Cognitive Psychol. 8, 453-64.
A hybrid speech enhancement system based on HMM and spectral subtraction

In this paper we describe a speech enhancement system based on spectral subtraction and a proposed AR-HMM-based pause detection algorithm. When trained off-line with limited types of environmental noises, the system performs well under almost all types of environmental noises. We show that the proposed pause detection method is at least one order of magnitude faster than the traditional correlation-based algorithms, and at the same time, has a better performance in locating long pauses in noisy speech. A method of musical noise reduction is also applied in this work. The hybrid speech enhancement system is implemented on a Pentium-166 PC. Using a standard sound card or digital audio interface, the system works in real-time with a negligible solid delay. The speech enhancement experiments using the hybrid system and the conventional spectral subtraction method clearly demonstrate the superiority of the proposed pause detection approach.
IMPACT OF CLASS II MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGEN EXPRESSION ON THE IMMUNOGENIC POTENTIAL OF ISOLATED RAT VASCULAR ENDOTHELIAL CELLS

We have investigated the immunogenic potential of rat heart vascular endothelial cells by their ability to induce an accelerated rejection of a relevant heart allograft, and related the immunogenic potential to the expression of class II major histocompatibility complex (MHC) antigens on the endothelial cell surface. Only 12% of freshly isolated rat vascular endothelial cells express class II antigens in serum-free medium, and the level of expression is low as judged by immunoperoxidase staining and/or the ability of endothelial cells to bind staphylococci to the cell surface after treatment with monoclonal antibodies to the class II molecule. On the other hand, 99% of the endothelial cells under the same conditions express class I, and the level of expression is high. The class II antigen expression of vascular endothelial cells can be upregulated to more than 98% by recombinant gamma-interferon in vitro—and, con
Correlation of Total Cholesterol and Glucose in Serum of Iraqi Patients with Atherosclerosis and Diabetes Mellitus Type 2

Cholesterol is a fatty substance (lipid) classified as a waxy steroid of fat. It is absorbed by the intestine into blood stream and is packaged inside a protein coat a chylomicron. Blood glucose is a simple monosaccharide absorbed directly into the blood stream during digestion. The level of blood glucose normally represents a balance between the inflow of glucose into blood and it is uptake by the tissue. Atherosclerosis is a general term for a number of different medical conditions that affect the heart, this is occurs when the blood supply to a part of heart is interrupted, must commonly due to plaque, is build up in the coronary arteries consist of lipid cholesterol and calcium. It causes a damage of potential disease of heart muscle due to thickening and hardening of arteries. Diabetes mellitus is a disorder in which the level of blood glucose is persistently elevated above the normal range due to decrease secretion of insulin. The main objective of this study is to determine the concentrations of total cholesterol and glucose into blood serum of Iraq patients with atherosclerosis and diabetes mellitus type 2. This study included 60 specimens of patients with atherosclerosis and 60 patients with type 2 diabetes mellitus; their age range was 45-65 years. These patients were then matched by age and sex to 30 healthy individuals. Results revealed that there was highly significantly increased in the mean value of total cholesterol and glucose concentrations in patients of atherosclerosis (p<0.001) and diabetes mellitus (p<0.001) as compared with healthy individuals.
Secrecy Outage on Transmit Antenna Selection/Maximal Ratio Combining in MIMO Cognitive Radio Networks

This paper investigates the secrecy outage performance of transmit antenna selection (TAS)/maximal ratio combining (MRC) in multiple-input-multiple-output (MIMO) cognitive radio networks (CRNs) over Rayleigh fading channels. In the considered system, a secondary user (SU-TX) equipped with NA (NA ≥ 1) antennas uses TAS to transmit confidential messages to another secondary user (SU-RX), which is equipped with NB (NB ≥ 1) antennas and adopts the MRC scheme to process multiple received signals. Meanwhile, an eavesdropper equipped with NE (NE ≥ 1) antennas also adopts the MRC scheme to overhear the transmitted information between SU-TX and SU-RX. SU-TX adopts the underlay strategy to guarantee the quality of service (QoS) of the primary user (PU) without spectrum sensing. In this paper, we derive the exact and asymptotic closed-form expressions for the secrecy outage probability (SOP). Simulations are conducted to validate the accuracy of the analysis.
Brightness perception in complex fields.

Results of brightness-scaling experiments with complex stimulus fields are reported. A family of brightness functions has been computed from the data for complex stimuli such as photographic reproductions viewed with both illuminated and dark surrounds. The resulting brightness vs luminance functions are not simple power functions. They exhibit exponential decay from the power form as a function of both screen luminance and surround luminance; i.e., they are nonlinear in log–log coordinates.
High-Stringency Evaluation of the Automated BD Phoenix CPO Detect and Rapidec Carba NP Tests for Detection and Classification of Carbapenemases

ABSTRACT There is an urgent need for rapid, accurate detection and classification of carbapenemases. The current study evaluated the automated BD Phoenix CPO Detect and the manual bioMérieux Rapidec Carba NP tests for meeting these needs. Both tests were challenged with 294 isolates of Enterobacteriaceae spp. , Pseudomonas aeruginosa, and Acinetobacter baumannii chosen to provide extreme diagnostic difficulty. Carbapenemases such as KPC, NMC-A, IMI, SME, NDM, SPM, IMP, VIM, and OXA-23, 40, 48, 58, 72, 181, and 232 were produced by 243 isolates and 51 carbapenemase-negative isolates included porin mutants and producers of extended-spectrum β-lactamases (ESBLs), AmpCs, K1, and broad-spectrum β-lactamases. Both tests exhibited high sensitivity of carbapenemase detection (>97%). Due to the highly challenging carbapenemase-negative isolates, specificities were lower than typical for evaluations involving mostly routine clinical isolates. BD Phoenix CPO Detect was 68.6% specific and Rapidec Carba NP was 60.8% to 78.4% specific, depending on how borderline results were interpreted. Only BD Phoenix CPO Detect classified carbapenemases. It correctly classified 85.0% of class A, 72.4% of class B, and 88.6% of class D carbapenemases. Importantly with respect to empirical therapy with new β-lactamase inhibitor combinations such as ceftazidime/avibactam, no class B carbapenemases were misclassified as class A carbapenemases. Both tests offer advantages. Used alone, without initial susceptibility tests, Rapidec Carba NP can provide positive results for some isolates after only 10 to 30 min incubation. BD Phoenix CPO Detect provides novel advantages such as automated carbapenemase detection, inclusion in susceptibility panels to eliminate delays and subjectivity in initiating carbapenemase tests, and classification of most carbapenemases.