Miracle-dz/UniFAR-FTUs huggingface dataset:
‘Slightly more serious than a cold’: Do patients, nurses and GPs take type 2 diabetes seriously?

What people know and how people feel about type 2 diabetes will affect demand for early identification of the disease at an asymptomatic stage. This paper reports on the selected findings from a broader study of the attitudes and perceptions of GPs, nurses and patients about screening for type 2 diabetes. Purposive sampling was used to identify several practices across north-east England, and data were collected via semi-structured interviews with GPs, nurses and patients from these practices. Interview transcripts were analysed by drawing on the principles of grounded theory, with the aid of NUD*IST software. This paper focuses upon the perceived seriousness of this condition, and the implications such perceptions may have in practice. Results indicate a marked variation in perceptions of seriousness between health practitioners and patients. This diversity can be explored via three overlapping frameworks identified during the study: medical, political and personal. A medical framework suggests that individuals' perceptions are guided by a medical model. This links the seriousness of type 2 diabetes with concepts of prevention and cure, a need for individual lifestyle change, bias towards younger patients and anticipated use of medication. In short, diabetes is perceived to be more serious as it becomes more medicalized. A political framework views seriousness in terms of national incentives and priorities, a recognized need for a centralized push for early detection and financial inducements. Diabetes detection is not generally thought to be attractive politically compared with systematic cancer screening. A personal framework suggests that perceptions of seriousness are determined by individual attitudes, knowledge and experiences of diabetes. The findings offer important insights into how perceptions of the seriousness of type 2 diabetes may influence detection and management of this disease in primary care.
Audio-Vision: Sound on Screen

The Audiovisual ContractProjections of Sound on ImageThe Three Listening ModesBeyond Sounds and ImagesLines and Points: Horizontal and Vertical Perspectives on Audiovisual RelationsThe Audiovisual SceneThe Real and the RenderedPhantom Audio-VisionSound Film--Worthy of the NameTelevision, Video Art, Music VideoToward an Audiologovisual PoeticsIntroduction to Audiovisual Analysis
Catechol‐O‐methyltransferase inhibitors: Clinical potential in the treatment of Parkinson's disease

Substitution therapy with levodopa and a peripheral inhibitor of aromatic L‐amino acid decarboxylase (AADC) is the cornerstone in the treatment of Parkinson's disease. Chronic therapy with levodopa, however, is associated with the occurrence of motor complications that are partially related to the pharmacokinetics of levodopa. The formation of 3‐O‐methyldopa (3‐OMD), a long‐lived metabolite that confers no clinical benefit, is catalyzed by catechol‐O‐methyltransferase (COMT), an enzyme that is particularly abundant in the gastrointestinal tract, liver, and kidneys. Potent, reversible, selective, and orally active COMT inhibitors have become available. The nitrocatechols, entacapone and tolcapone, have undergone extensive clinical testing as adjuncts to levodopa in the therapy of Parkinson's disease. Studies in healthy subjects and parkinsonian patients have shown the inhibitory effect of both drugs on the formation of 3‐OMD, leading to an increase in levodopa bioavailability and elimination half‐life, without a change in peak plasma concentrations (Cmax) or time to reach Cmax (tmax). In patients, COMT inhibitors significantly prolong and smooth, i.e., reduce peak‐trough fluctuations, the effects of levodopa, as reflected in improved motor scores and lengthened duration of ON time (periods of good response) without an influence on the time to onset of action or the peak effect. Entacapone 200 mg is given in conjunction with each levodopa dose, whereas tolcapone is administered in a fixed 100 to 200 mg t.i. d. dosing regimen. The tolerability profiles of the two drugs are similar, with urine discoloration and an increase in dopaminergic side effects such as nausea, orthostatic hypotension, and dyskinesias being most prominent. Tolcapone induces a higher incidence of diarrhea and liver enzyme abnormalities. It is anticipated that COMT inhibitors will prove beneficial in extending and smoothing the effects of levodopa in patients with Parkinson's disease and end‐of‐dose wearing‐off fluctuations. Drug Dev. Res. 42:1–25, 1997. © 1997 Wiley‐Liss, Inc.
Immunoglobulin levels may aid in the prediction of treatment response in anti-CD20 treatment of multiple sclerosis

Background: Anti-CD20 therapies are an emerging treatment strategy in multiple sclerosis (MS). Objective: Retrospective analysis of efficacy and safety in an MS cohort treated with rituximab (RTX) with identification of potential treatment response predictors. Methods: This retrospective study describes a monocentric cohort of 30 MS patients treated with RTX in a routine clinical setting. Patient characteristics, disease course, clinical and magnetic resonance imaging (MRI) treatment response markers, and laboratory assessments were analyzed. Logistic regression analysis corrected for demographic characteristics was used to identify treatment response predictors. Results: The RTX-treated cohort (mean age at RTX initiation 48 years (SD 14)) comprised patients with relapsing-remitting MS (n = 9), primary progressive MS (n = 11), and secondary progressive MS (n = 10). Two-thirds of patients had at least one MS medication prior to RTX; 27.6% of patients improved on the Expanded Disability Status Scale during RTX, whereas 72.4% of patients were stable or worsened. Based on this classification, we identified the presence of gadolinium enhancement in MRI before RTX as a predictor of response (odds ratio (OR) 12.2, confidence interval (CI) 1.02–144.55). After receiver operating characteristic curve definition of immunoglobulin (Ig) class cutoffs and creation of a sum score, the latter also predicted RTX response (OR 5.15, CI 1.21–21.88). Infectious complications were seen in three patients under RTX treatment. Conclusion: With the limitation of the retrospective approach and small sample size, this study confirms gadolinium enhancement before treatment initiation as a predictor of anti-CD20 response in MS. Lower Ig levels were associated with RTX response; however, these will have to be further investigated for a potential role for infectious complications.
The challenges for families managing an adolescent with an intellectual disability and type 1 diabetes

Objective This paper describes the experiences of two families caring for their adolescent sons who have type 1 diabetes (T1D) and an intellectual disability. Design This paper arises from a larger study and reports on the findings from four parents, (two couples), who have adolescent sons with both type 1 diabetes and intellectual disability. Case study analysis of these interviews gave a more in‐depth understanding of management of these dual conditions from the perspective of the parents. Setting The interviews occurred in the parents homes. Subjects Family one consisted of a mother, father, and three children aged 16 to 20 years. Family two comprised both parents and four children attending secondary school. At the time of the study all siblings were living at home. The two adolescent men with intellectual disability and T1D were 19 year old, still living at home and attending sheltered employment. Main Outcome Measures This paper describes the experiences of two families caring for their adolescent sons who have T1D and an intellectual disability. Results Independence was the major issue. Obtaining independence was hindered on several fronts: having an intellectual disability and having to manage T1D concurrently, and the short and long‐term effects this management has on the family now and in the future. Conclusion The complex management of T1D coupled with intellectual disability makes independence more difficult to attain for these adolescents. The parents in this study accepted that full independence may not be possible for their sons and voiced concern for their future wellbeing. The challenges for families managing an adolescent with an intellectual disability and type 1 diabetes Jennifer Evans BHS (Nursing), MNSt, EdD, RN Lecturer, School of Nursing, Faculty of Health Sciences, Australian Catholic University, NSW, Australia. Level 7, 33 Berry Street, North Sydney NSW PO Box 968, North Sydney NSW jennifer.evans@acu.edu. au AUTHORS Sharon Hillege BHS (Nursing), Grad Cert TESOL, PhD, RN, RM Senior Lecturer, School of Nursing and Midwifery, University of Western Sydney, NSW. Locked Bag 1797 Penrith, NSW, Australia. s.hillege@uws.edu. au Susan Gallagher BEd (Nursing), MA(Ed), RN, RMRN, RPN Senior Lecturer, School of Nursing, Faculty of Health Sciences, Australian Catholic University, NSW, Australia. Level 7, 33 Berry Street, North Sydney NSW 2060 PO Box 968, North Sydney NSW 2059
Prohexadiona de calcio reduce crecimiento vegetativo e incrementa brotación floral en mango ‘Ataulfo’

La produccion irregular en mango se atribuye a variacion en la floracion. Prohexadiona de calcio (P-Ca) reduce crecimiento vegetativo y favorece floracion en frutales templados como manzano y subtropicales como aguacate. En mango ‘Ataulfo’, no hay informacion al respecto. El objetivo fue determinar dosis, epoca y numero de aplicacion de P-Ca en mango ‘Ataulfo’ con la finalidad de asegurar floracion y encontrar un sustituto para paclobutrazol (PBZ). El estudio se realizo de 2012 a 2014 en Tepic y San Blas Nayarit, en ambos anos, los arboles fueron podados despues de cosecha. Experimento 1 y 2: P-Ca (150, 250 y 500 mg L-1) a 0+10+20+30 dias despues de la poda (ddp) y 30+45+60 ddp, respectivamente. Experimento 3: P-Ca (500 mg L-1) una, dos o tres aplicaciones a 0, 0+10 y 0+10+20 ddp y Experimento 4: P-Ca (150 y 500 mg L-1) a 30+45+60 ddp y 1 500 mg L-1 en una sola aplicacion (1 x) 30 ddp. En todos los experimentos se incluyo un tratamiento estandar de PBZ (2 500 mg L-1) 30 ddp y un testigo (agua mas surfactante). El diseno fue completamente al azar, 6 repeticiones, un arbol como unidad experimental. En Experimento 2, se logro reducir un 35% el crecimiento vegetativo con P-Ca 500 mg L-1 (3 x) entre 30-60 ddp. Esta misma dosis de P-Ca (500 mg L-1) (3 x) a 30, 45 y 60 ddp, o una sola aplicacion (1 500 mg L-1) 30 ddp logro igual el efecto de PBZ en adelanto (20-35 dias) y porcentaje de floracion. En los dos ciclos, ambos productos mejoraron amarre y produccion de fruto. Con base a los resultados obtenidos se considera que P-Ca pudiera ser un sustituto para PBZ en mango ‘Ataulfo’ para asegurar floracion y producciones regulares ano con ano.
Clinics in Plastic Surgery

As of January 1974, WB Saunders Company will begin publishing a new clinics series, this one entitled Clinics in Plastic Surgery . The size of the volumes will be 6×9 inches with an average of 200 pages, and will be issued quarterly beginning in January of each year. The journal should have a distinct appeal to otolaryngologists, and the subject matter relates to the area of the head and neck. Consequently a single copy rate of $18 may be preferred to the annual subscription rate of $50 if a preponderance of otolaryngologic material should be covered. In this respect it may be valuable to both publisher and otolaryngologist alike if advance notice of table of contents could be made available. Volume 1 covers plastic surgery in the non-Caucasian. Volume 2 will cover problems in intersex. Volume 3 will cover horizons in plastic surgery. Volume 4 will cover burns.
RESPONSE LETTER TO DRS. O'CALLAGHAN AND O'NEILL

We appreciate the important issues detailed by O'Callaghan and O'Neill, although our reading of the evidence is that, despite the majority of safe older drivers, there is a proportion of older drivers who may be unsafe because of cognitive impairment. Given population aging, the size of this subgroup will increase. Persons classified as cognitively impaired (including those with a mean Mini-Mental State Examination (MMSE) score of 26.5 or MMSE scores of ≤26) have demonstrated poorer driving performance in on-road driving assessments, crashes, driving simulators, and other performance measures. Although many older adults may begin to modify their driving behaviors, reducing their exposure to higher-risk situations, such modifications may not be sufficient for drivers who are at greater risk of crashing. Our study identifies a large proportion of older drivers with MMSE scores of 26 or lower. Additionally, the sample is likely to be biased toward higher-functioning older adults because of selection effects at entry to the studies, hence underestimating the numbers with possible cognitive impairment.
Achieving Anonymity with Fully Anonymous Attribute-Based Encryption and Controlling Access Privilege in Cloud

: Cloud computing could be a revolutionary computing paradigm, that allows versatile, on-demand, and inexpensive usage of computing resources, however the info is outsourced to some cloud servers, and varied privacy considerations emerge from it. Various schemes Supported the attribute-based coding have been projected to secure the cloud storage. However, most work focuses on the info contents privacy and therefore the access management, while less attention is paid to the privilege management and therefore the identity privacy. During this paper, a semi anonymous privilege management theme AnonyControl is proposed to handle not solely the data privacy, however conjointly the user identity privacy in existing access control schemes. Anony Control decentralizes the central authority to limit the identity run and therefore achieves semi anonymity. Besides, it conjointly generalizes the file access management to the privilege control, by that privileges of all operations on the cloud knowledge can be managed in an exceedingly fine-grained manner. Afterwards, the Anony Control-F is presented, that totally prevents the identity leakage and succeed the complete namelessness. The security analysis shows that each Anony Control and Anony Control-F square measure secure under the decisional linear Diffie–Hellman assumption, and new performance analysis exhibits the practicableness of new schemes.
The development of social well-being in new extra care housing schemes. Funded/commissioned by: Joseph Rowntree Foundation

Extra care schemes provide care and support so that older people can live independently. They also aim to prevent residents feeling isolated by providing opportunities for social interaction. This research examined how social well-being developed in 15 new-build housing schemes supported by the Department of Health’s Extra Care Housing Funding Initiative. Please follow this link to <a href= http://www.jrf. org.uk/publications/well-being-extra-care-schemes >Joseph Rowntree Foundation for the Summary and Full Report.
Primary glass from Israel and the production of glass in Late Antiquity and the early Islamic period

On presente les resultats des analyses des elements majeurs de blocs de verre et de quelques fragments de vaisselle en verre provenant d'une serie de sites d'Israel, datant de l'epoque byzantine et de l'epoque islamique (Ve -IXe s.). Tous les verres sont de composition « soda-lime-silica » et les donnees sont compatibles avec l'idee d'un changement de la source sodique au IXe siecle qui passe du natron aux cendres de plantes. Les verres au natron utilisent un sable calcaire comme source de silice et de chaux tandis que les verres aux cendres de plantes emploient une source de silice relativement pure, la chaux provenant des cendres de plantes. La dalle de verre de Bet She'arim semble etre le resultat d'un echec du a l'utilisation de deux composants porteurs de chaux, des cendres de plantes et du sable calcaire. Les verriers de Bet Eli'ezer produisaient un verre au natron et semblent avoir charge leur four en differentes fournees de matieres premieres. Les analyses des verres provenant de quatre fours a bassin de Bet El'ezer indiquent que les verriers produisaient un verre relativement stable qui avait une composition de 73-76% de S1O2 et de 11-13% de Na2O. Les verres byzantins des VIe et VIIe siecles des sites de Dor et d'Apollonia, ont des pourcentages plus eleves de soude et moins eleves de silice, mais les verres de Bet El'ezer trouvent un bon parallele dans des verres du VIIIe siecle provenant de Ramla. Les verres d'Israel peuvent etre distingues des verres egyptiens de la seconde partie du premier millenaire en se fondant sur leurs elements majeurs ; ils different aussi de verres romains d'Europe occidentale, jetant quelques doutes sur l'idee selon laquelle la majorite des verres romains etait fait avec le sable de la riviere Belus. Des analyses preliminaires des elements traces confirment les distinctions entre les groupes de verre, qui peuvent etre expliques en termes de geologie regionale et de matieres premieres employees.
Cervicofacial Necrotising Fasciitis of Odontogenic Origin: A Review

A ‘Killer or flesh eating Bug’ as known to the Military surgeon of past centuries [1] was due to its nature of rapid spread along the facial planes to involve the sub cutaneous tissues, fascia, skin and possibly muscle[1,2]. Copious amount of foul-smelling pus are typically produced. Blood vessels become thrombosed, and ultimately tissue death occurs [1,3]. Now well known as Necrotizing fasciitis, due to presence of innumerable data, has become a common complication as an exacerbation of pre-existing infection.
A controlled language-based evaluation approach to ensure image accessibility during web localisation

In spite of recent improvements in non-visual web access, images on the web still present an accessibility barrier to screen reader users. For this population group the presence of inappropriate text alternatives for images, or simply their absence, usually results in a poor web user experience. In this paper, we propose a controlled language (CL) rule-based approach that enables translation professionals to ensure image accessibility during the web localisation process. We describe the set of 40 CL rules we developed and then present the results of the evaluation of a selection of ten rules from the set. During the study, which sought to assess their impact on the appropriateness of text alternatives in French, the ten rules were applied using Acrolinx, a state-of-the-art CL checker. The results of the evaluation suggest that this sub-set of ten rules can help translators significantly improve the level of image accessibility obtained in the localised web product.
Exploiting structure for scalable software verification

Software bugs are expensive. Recent estimates by the US National Institute of Standards and Technology claim that the cost of software bugs to the US economy alone is approximately 60 billion USD annually. As society becomes increasingly software-dependent, bugs also reduce our productivity and threaten our safety and security. Decreasing these direct and indirect costs represents a significant research challenge as well as an opportunity for businesses. Automatic software bug-finding and verification tools have a potential to completely revolutionize the software engineering industry by improving reliability and decreasing development costs. Since software analysis is in general undecidable, automatic tools have to use various abstractions to make the analysis computationally tractable. Abstraction is a double-edged sword: coarse abstractions, in general, yield easier verification, but also less precise results. This thesis focuses on exploiting the structure of software for abstracting away irrelevant behavior. Programmers tend to organize code into objects and functions, which effectively represent natural abstraction boundaries. Humans use such structural abstractions to simplify their mental models of software and for constructing informal explanations of why a piece of code should work. A natural question to ask is: How can automatic bug-finding tools exploit the same natural abstractions? This thesis offers possible answers. More specifically, I present three novel ways to exploit structure at three different steps of the software analysis process. First, I show how symbolic execution can preserve the data-flow dependencies of the original code while constructing compact symbolic representations of programs. Second, I propose 1For details, see [1].
A Pilot Study of the Effectiveness of Using Leisure versus Activities of Daily Living to Increase Standing Tolerance in the Elderly Population

Objectives. The purpose of this pilot study was to investigate whether leisure activities are more effective than activities of daily living (ADL) in improving standing tolerance in an elderly population. Method. A single-case study AB design was used with five participants over the age of 75, who did not have adequate standing tolerance to complete their ADL. Baseline of standing tolerance was established while the participants performed ADL. Subsequent standing trials incorporated leisure activities. Results. Graphical analysis was used to demonstrate that for the five participants in this study, leisure activities were more effective than ADL in improving standing tolerance. Conclusions. Leisure activities can be used as an effective treatment tool to improve standing tolerance in the elderly. Further study is suggested to enable generalization of these results.
The prevalence of overweight and obesity in primary schoolchildren and its correlation with sociodemographic factors in Aydin, Turkey

Calisir H, Karacam Z. International Journal of Nursing Practice 2011; 17: 166–173 The prevalence of overweight and obesity in primary schoolchildren and its correlation with sociodemographic factors in Aydin, Turkey The purpose of the study was to determine the correlation of the prevalence of overweight and obesity among children in primary schools of central Aydin province with certain sociodemographic characteristics and the prevalence of overweight and obesity in the children's families. The study was cross-sectional and descriptive, and was done with 460 children aged 8–11 years. Study data were collected using a questionnaire. The study determined the children's overweight prevalence as 12.8% and their obesity prevalence as 13.7%. It was found that having a family with four or fewer members increased the risk of overweight and obesity (odds ratio (OR) = 1.889; 95% confidence interval (CI) = 1.086–3.287), that the mother's education level of secondary school or less decreased the risk of overweight and obesity of children (OR = 0.458; CI = 0.268–0.780), and that the greater the mother's (OR = 1.069; CI = 1.008–1.133) and father's (OR = 1.127; CI = 1.049–1.210) body mass index, the more pronounced was the children's risk of being overweight. This study showed that the prevalence of overweight (12.8%) and obesity (13.7%) is high among children aged 8–11 years, and that this condition is correlated with the number of family members and the parents' body mass index.
Effects of feeding different races of silkworm (Bombyx mori L.) with mulberry (Morus indica L.) leaves varying in ploidy level

Une etude a ete realisee afin d'examiner la possibilite d'isoler une lignee de murier rentable, susceptible de produire suffisamment de feuilles de bonne qualite adaptees a l'elevage des vers a soie. Cette etude porte sur l'evaluation du nourrissage des larves avec des feuilles de murier de differents degres de ploidie sur leur developpement et les cocons obtenus. Quatre races de vers a soie (Bombys mori L.), deux de type bivoltin exotique et deux de type polyvoltin indigene, ainsi que toutes leurs combinaisons de croisement possibles ont ete choisies pour cette etude. Le taux d'ingestion de la nourriture, le pourcentage de digestibilite et les efficacites de conversion de la nourriture ingeree et digeree en matiere corporelle chez les larves de vers a soie (B. mori L.) au cours du 5 e âge ont ete determines pour le diploide initial (M. indica L.) et ses derives triploides et tetraploides