Miracle-dz/UniFAR-FTUs huggingface dataset:
Introdução à teoria da cor

O estudo da percepcao cromatica e requisito basico para estudantes das areas que desenvolvem suas principais articulacoes no âmbito visual. Assim, a Teoria da Cor e fundamental para uma ampla faixa de cursos, indo desde o Design ate a Arquitetura. Este livro foi pensado para auxiliar, por um lado, o professor das disciplinas que envolvem Teoria da Cor, e por outro, os alunos destes cursos, principalmente no processo da construcao cultural simbolica da cor. Profissionais da area tambem encontrarao aqui importantes informacoes para a aplicacao da cor em projetos.
Characterization of the dTDP‐rhamnose biosynthetic genes encoded in the rfb iocus of Shigella flexneri

The nucleotide sequence of the proximal half of the rfb region of Shigella flexneri has been determined, and the genes encoding enzymes involved in the biosynthesis of dTDP‐rhamnose have been identified. These genes show strong homology to the rfb genes encoding dTDP‐rhamnose biosynthesis in Salmonella enterica serovar typhimurium (strain LT2) and S. enterica serovar anatum (strain M32) (Jiang et al., 1991; Wang et al., 1992). An open reading frame upstream of rfbB was also identified which encoded a protein having strong similarity with GalU, and has been designated galF. GalF has 92% amino acid sequence identity with an S. enterica LT2 gene, orf2X8, which is similarly situated upstream of rfbB (Jiang et al., 1991). The T7 expression system was utilized to identify proteins corresponding to those predicted from DNA sequence analysis. The similarity of the predicted proteins with proteins that are functionally identical or related, and with others of unknown function from the Yersinia enterocolitica O3 rfb region, and in the Escherichia coli K‐12 rff region are also described. We have re‐addressed the assignment of each gene of the dTDP‐rhamnose pathway with the known enzymes of the pathway, in particular rfbC and rfbD. A reporter plasmid to detect genes encoding enzymes of the dTDP‐rhamnose pathway is described. An analysis of the intergenic region between galF and rfbB has been made, and comparison with the same region from S. enterica LT2 discussed.
Variation in the relative copy number of the TLR7 gene in patients with systemic lupus erythematosus and healthy control subjects.

OBJECTIVE To determine whether there is an increase in the number of TLR7 gene copies in patients diagnosed as having systemic lupus erythematosus (SLE) and whether gene amplification influences the autoantibody profiles in SLE patients, as has recently been reported in the BXSB/Yaa mouse model of lupus. METHODS We used a modified real-time quantitative polymerase chain reaction protocol to calculate the relative TLR7 gene copy number according to the comparative 2(-DeltaDeltaC(t) ) method in 99 SLE patients and 91 healthy controls matched for sex and ethnicity. Autoantibody profiles were determined by standard methods. RESULTS The relative number of TLR7 gene copies in SLE patients and healthy controls varied; however, no significant concordance between the number of relative gene copies and the SLE phenotype was found. There was also no difference in variation by ethnic group. Comparison of the relative gene copy numbers according to the presence or absence of antinuclear antibodies (ANAs), the ANA staining patterns, and the presence or absence of anti-RNA-associated antigen antibody showed no statistically significant difference in the SLE patients. CONCLUSION We determined that although the relative gene copy number of TLR7 varied in both SLE patients and healthy controls, it was not significantly increased among our SLE patients as compared with our controls. We found no detectable trend for an association between the relative gene copy number and the autoantibody profile in SLE patients.
The paradigm shift to communication and the question of subjectivity : reflections on Habermas, Lacan and Mead

Dans le cadre de l'opposition entre la philosophie de la conscience et la theorie de l'agir communicationnel etablie par Habermas, l'A. compare le changement de paradigme rationnel revendique par Habermas a la conception de l'intersubjectivite linguistique developpee par Lacan, ainsi qu'a la theorie de la socialisation de l'individu defendue par Mead
Duodenal duplication cyst in a young cat

INTESTINAL duplications are uncommon congenital malformations, which can occur anywhere along the gastrointestinal tract, from the tongue to the rectum, with a variety of clinical presentations; they are most commonly observed in young animals and children ([Macpherson 1993][1], [Haziroglu and
Effects of feedback motives on inquiry and performance

Purpose – The purpose of this paper is to examine how two motives for feedback-seeking behavior, the instrumental and image enhancement motives, impact the feedback-seeking process and supervisor ratings of task performance. Design/methodology/approach – Correlational data were collected from supervisor-subordinate dyads and analysed with path analysis. Findings – Results show that perceptions of a supportive supervisory feedback environment are associated with both higher instrumental and image enhancement motives. The instrumental motive fully mediates the relationship between the feedback environment and feedback-seeking behavior. However, the positive effect of feedback-seeking behavior on task performance ratings made by supervisors is only significant when the image enhancement motive is low. Contrary to expectations, no direct or moderating effects were found for the instrumental motive on performance ratings. Practical implications – These results demonstrate that many instances of feedback-seekin.
Prevalence of cardiovascular disease and cancer during cross-sex hormone therapy in a large cohort of trans persons: a case-control study.

OBJECTIVE This study evaluated the short- and long-term cardiovascular- and cancer-related morbidities during cross-sex hormone therapy in a large sample of trans persons. SUBJECTS AND METHODS A specialist center cross-sectional study compared 214 trans women (male-to-female transsexual persons) and 138 trans men (female-to-male trans persons) with an age- and gender-matched control population (1-3 matching). The participants were on cross-sex hormone therapy for an average of 7.4 years. We assessed physical health and possible treatment-related adverse events using questionnaires. RESULTS Five percent of trans women experienced venous thrombosis and/or pulmonary embolism during hormone therapy. Five of these adverse events occurred during the first year of treatment, while another three occurred during sex reassignment surgery. Trans women experienced more myocardial infarctions than the control women (P=0.001), but a similar proportion compared with control men. The prevalence of cerebrovascular disease (CVD) was higher in trans women than in the control men (P=0.03). The rates of myocardial infarction and CVD in trans men were similar to the control male and female subjects. The prevalence of type 2 diabetes was higher in both trans men and women than in their respective controls, whereas the rates of cancer were similar compared with the control men and women. CONCLUSION Morbidity rate during cross-sex hormone therapy was relatively low, especially in trans men. We observed a higher prevalence of venous thrombosis, myocardial infarction, CVD, and type 2 diabetes in trans women than in the control population. Morbidity rates in trans men and controls were similar, with the exception of the increased prevalence of type 2 diabetes.
A Bacteriologic Census of Human Saliva

A LTHOUGH qualitative studies have described many genera and species from numerous oral locations, only scant information is available as to the relative populations of even those organisms which can be cultured. The present study was initiated to obtain such information. Kraus and Gaston' presented the population means for total aerobes, total streptococci, and Streptococcus salivarius. Krasse2 determined the means for streptococci in addition to those of lactobacilli and yeast. Green and Dodd3 compared 7 salivary populations of caries-immune and caries-susceptible subjects. A limited census of salivary organisms has on occasion been determined as an incidental part of an investigation. 5 The framework of any census is dependent upon the availability and excellence of the selective media. Recently, several improved selective media have been described. For example, Rogosa, Mitchell, and Wiseman6 devised a medium for lactobacilli, Douglas7 and Rogosa8 used lactate-containing media to demonstrate the large population of Veillonella present in saliva, and an improved selective medium for Fusobacterium has been introduced by Omata and Disraely.9 Several quantitative studies have been made on saliva in which 1 to 3 groups of organisms have been surveyed. Experimental designs have been markedly heterogeneous, especially as to saliva analyzed (stimulated or nonstimulated), agitation of specimen (none or mechanically shaken), and media. In only a few studies3' 10, 11 have as many as 7 to 10 salivary bacterial populations been investigated. Thus, a study which surveyed a large number of salivary bacterial categories simultaneously, using a simple and adequately described experimental design, seemed desirable. This study constitutes a census of 14 groups of organisms cultured from human saliva.
Effects of ryanodine on development of myogenic response in rat small skeletal muscle arteries.

OBJECTIVE The aim was to elucidate the functional role of the sarcoplasmic reticulum in myogenic contraction. METHODS Small arteries which perfuse the rat gracilis muscle were isolated and cannulated. The inner diameter was measured under no flow condition. Myogenic contraction was induced by increasing transmural pressure from 40 to 100 mm Hg. The diameter transient and the steady state internal diameter were analysed at 40 (ID40) and 100 mm Hg (ID100) of lumen pressure. RESULTS In control, the vessels dilated immediately after the pressure change, and then constricted over approximately 4 min (the diameter decay). ID40 and ID100 were 120(SEM 16) and 108(12) microns (n = 6, p < 0.05), respectively. Ryanodine (10(-5) M) decreased ID40 to 82(8) microns. The relative rate of the diameter decay in the first 1 min was lower in the ryanodine treated vessels than in control, at 43(1)% v 74(7)%, n = 6 (p < 0.05). While KCl constriction was similar to that of ryanodine, the diameter decay was identical to that of control. Thus a decrease in baseline diameter was not of itself the cause of the depressed rate of diameter decay in the ryanodine treated vessels. Nisoldipine (10(-6) M) abolished myogenic contraction. CONCLUSIONS Ryanodine sensitive sarcoplasmic reticular function is probably involved in the mechanism for developing the myogenic response in rat skeletal muscle small arteries.
Terapia Neuromotora Intensiva favorece manutenção do controle de cabeça e tronco em crianças com Amiotrofia Espinhal: Série de casos

A amiotrofia espinhal (AME) e uma doenca genetica recessiva, degenerativa e progressiva com alteracoes dos neuronios que estao localizados no corno anterior da medula, com consequencia fraqueza muscular generalizada e atrofia. A fisioterapia e indicada para manutencao de funcoes e incremento na qualidade de vida, havendo evidencias iniciais de efeitos positivos com a terapia neuromotora intensiva (TNMI), embora com controversias na literatura sobre os efeitos e indicacoes de exercicios de resistencia. O objetivo desse estudo foi verificar as habilidades motoras grossas de criancas com AME tipo II que realizam tratamento neuromotor intensivo. Para isso realizou-se um estudo retrospectivo, longitudinal por meio da analise dos escores da GMFM do prontuarios de 3 casos de criancas (2, 4 e 7 anos) durante 4 modulos de TNMI. Os resultados demonstram que as criancas teve um ganho e/ou manutencao durante cada modulo, tendo perda parcial dos escores durante periodo de destreino. De maneira geral conclui-se que mesmo sendo uma patologia progressiva a TNMI permitiu melhora e/ou manutencao de aspectos motores globais em criancas com AME, especialmente em itens relacionados ao controle de tronco e cabeca.
The Effects of Haemophilia on the Postural Control of Adolescents

A small number of studies have reported that children and adults with haemophilia have impaired balance control and show faster body sway during upright stance than healthy individuals. A decrease of somatosensory information due to multiple bleedings has been suggested to explain this difference. Therefore, the objective of this study was to examine if haemophilia is related to a decreased balance control under altered visual and proprioceptive conditions in male adolescents. Postural sway of healthy (n = 12, Age = 14.8 ± 1.4 years; BMI = 19.8 ± 1.8 kg/m2) and haemophiliac (n = 8, Age = 15.0 ± 1.4 years; BMI = 20.4 ± 3.2 kg/m2) male adolescents was measured with a force platform for normal quiet stance lasting 30 s with open and closed eyes on hard and foam floor conditions. The ANOVA revealed a significant Group × Vision × Proprioception (F(1,18) = 5.861, p < 0.05) interaction. Both groups showed an increased centre of pressure (COP) speed when vision and proprioception are challenged. Planned comparisons revealed that the haemophiliac group oscillated at a faster COP speed than the healthy group when vision is altered in hard floor (1.11 ± 0.27 versus 0.76 ± 0.19 cm/s; p < 0.05) and foam floor (6.83 ± 1.68 versus 4.89 ± 1.05 cm/s; p < 0.01) conditions. More important, haemophiliac adolescents were more disturbed by the proprioceptive condition and had a significantly higher COP speed on the foam even if vision is available (3.02 ± 0.47 versus 2.34 ± 0.45 cm/s; p < 0.05) compared to the healthy adolescents. In conclusion, haemophilia clearly affects postural control in altered sensory conditions. Our results suggest that haemophilia has a negative impact on the capacity of male adolescents to adequately use proprioceptive information for posture control.
A Comparative Study of 200 Fine Needle Aspiration Biopsies Performed by Clinicians and Cytopathologists

Fine needle aspiration (FNA) biopsy is a useful tool in the diagnosis and management of suspicious masses. Most FNA biopsies of palpable masses can be performed without radioguidance by either clinicians or cytopathologists; however, it is unclear if there is a difference in the diagnostic yield of the procedure based on who performs the FNA. We reviewed the FNA biopsy results of 200 patients presenting with head and neck masses to a tertiary care center from 2003 to 2004. One hundred FNA biopsies were performed by clinicians and 100 performed by cytopathologists. Seventy‐one underwent subsequent surgical biopsy or definitive surgery. Results of the FNA biopsies performed by the clinicians and the cytopathologists were compared based on the percentages of FNAs that were diagnostic, suspicious/suggestive, and nondiagnostic. Additionally, the pathology results of the 71 surgical biopsies or resections were compared with the preoperative FNA results. Of the 100 FNA biopsies performed by cytopathologists, 83% were diagnostic, 10% were suspicious/suggestive, and 7% were nondiagnostic. Of the 100 FNA biopsies performed by clinicians, 24% were diagnostic, 43% were suspicious/suggestive, and 33% were nondiagnostic. Cytopathologists achieved significantly better results (P < .0001, two‐tailed t‐test). Of the 71 cases with surgical follow up (50 by cytopathologists and 21 by clinicians), 94% of cases performed by cytopathologists and 67% of those performed by clinicians show agreement with final surgical pathology results. Overall, the FNAs performed by cytopathologists show significantly better diagnostic accuracy (P = .0002134, two‐tailed t‐test). FNA provides valuable information in the workup of suspicious head and neck masses. Cytopathologists may achieve significantly better results.
JavaSPI: A Framework for Security Protocol Implementation

This paper presents JavaSPI, a "model-driven" development framework that allows the user to reliably develop security protocol implementations in Java, starting from abstract models that can be verified formally. The main novelty of this approach stands in the use of Java as both a modeling language and the implementation language. The JavaSPI framework is validated by implementing a scenario of the SSL protocol. The JavaSPI implementation can successfully interoperate with OpenSSL, and has comparable execution time with the standard Java JSSE library.
Severe Hypothyroidism Leading to Life Threatening Menorrhagia

Background: In their life-time, 10% to 30% of reproductive-aged women will experience abnormal uterine bleeding. After ruling out a pregnancy, the initial laboratory investigations for these patients should be based on history and clinical examination. Hypothyroidism and hyperthyroidism can be associated with abnormal uterine bleeding. Case: A 49 year-old woman was brought to the emergency department for abnormal uterine bleeding. Her hemoglobin was 26 g/L and her TSH and free thyroxin (T4) levels were >100 mU/L (0.25 to 5.00) and 1 ρmol/L (12 to 22), respectively. Oral levothyroxine was then started. High-doses of conjugated estrogen and tranexamic acid were used as needed to control uterine bleeding and the menorrhagia resolved rapidly. Conclusion: Severe hypothyroidism can lead to significant uterine bleeding secondary to ovulation and coagulation disorders.
Bcl‐2 overexpression enhances the metastatic potential of a human breast cancer line

Bcl‐2 protein has been shown to contribute to oncogenesis because it can transform and immortalize cells in cooperation with c‐myc, ras, or viral genes. However, in vivo studies have not yet established whether bcl‐2 can play a role in metastasis. Here we investigate the potential metastatic role of bcl‐2. We introduced the human bcl‐2 gene into a low bcl‐2 expressing human breast cancer cell line MCF7 ADR. We demonstrate that two bcl‐2 overexpressing clones injected intravenously or intramuscularly into nude mice induce a significantly higher number of experimental and spontaneous lung metastases compared to the control transfectant clone. We demonstrate that bcl‐2 overexpressing clones are more invasive and migratory in response to chemotactic stimuli than the control transfectant clone. Furthermore, zymographic analysis shows that secretion of 72 and 92 kDa gelatinases increases in the two bcl‐2 overexpressing transfectants. Tumors originating from bcl‐2 overexpressing clones also show a decrease in the latency period of tumor appearance. In conclusion, our data show that bcl‐2 overexpression enhances both tumorigenicity and metastatic potential of MCF7 ADR cells by inducing metastasis‐associated properties. —Del Bufalo, D. , Biroccio, A. , Leonetti, C. , Zupi, G. Bcl‐2 overexpression enhances the metastatic potential of a human breast cancer line. FASEB J. 11, 947–953 (1997)
Double photoionization of H2: An experimental test of electronic-correlation models in molecules.

The double-photoionization cross sections of molecular hydrogen (H/sub 2/) and molecular deuterium (D/sub 2/) were measured by using the photoion-photoion coincidence method for photon energies ranging from the threshold energy around 50 eV up to, respectively, 140 and 98 eV. The comparison with the recent ab initio calculations of Le Rouzo (J. Phys. B 19, L677 (1986)) indicates that an important part of the double-photoionization process is accounted for by a rigorous description of the electron-electron interaction in the initial state. As a by-product of this work, it was also concluded that double photoionization of hydrogen can be considered as a vertical process and that Franck-Condon approximations are quite valid to calculate the kinetic energy of the resulting H/sup +/+H/sup +/ fragments.
Myotonia in related Chow Chow dogs.

Summary A myopathy associated with myotonia was observed in three related Chow Chow dogs. The clinical signs were first noticed at 2 to 3 months of age. They included muscle spasm and stiffness of gait which decreased in severity with exercise. Electromyographic findings and the demonstration of a muscle percussion dimple confirmed the presence of myotonia. Dystrophic changes were observed in muscle biopsies but histochemical techniques did not demonstrate fibre type changes. An inherited aetiology was suspected but not confirmed.
Radiation-induced meningioma: a descriptive study of 253 cases.

OBJECT Ionizing radiation is the only established risk factor recognized today in the causation of meningioma. The aim of the present report is to describe the demographic and clinical characteristics of a large series of 253 patients with radiation-induced meningiomas (RIMs). These parameters were compared with those of 41 patients with meningiomas in whom there was no previous history of irradiation (non-RIM group) and with other series of patients presented in the literature. METHODS The cases of RIM were recruited from a cohort of approximately 11,000 individuals who had been treated with ionizing radiation during childhood for tinea capitis and from a group of individuals who, as adults, applied for compensation because of that treatment. The non-RIM group was identified through the Israeli Cancer Registry. Exposure to radiation was carefully validated among all cases of RIM and absence of previous irradiation was verified for all patients in the non-RIM group. Significantly, a lower patient age at diagnosis, higher prevalence of calvarial tumors, higher proportion of multiple meningiomas, and a nonsignificant higher recurrence rate were observed among patients with RIM compared with the non-RIM group. The mean latency period from date of radiation exposure to development of a meningioma among the RIM group was approximately 36 years. CONCLUSIONS The findings of this study agree with those of other studies indicating the demographic, clinical, and even genetic variability between RIM and non-RIM cases. The existence of two different subtypes of meningiomas may have profound implications for screening, early diagnosis, and therapy of meningiomas.
Inflammatory leiomyosarcoma may be characterized by specific near‐haploid chromosome changes

Identical near‐haploid karyotypes with 28, X, +5, +18, +20, +21, +22 were found in two cases of inflammatory leiomyosarcoma, one of which had been reported previously as malignant fibrous histiocytoma. This abnormality may identify these tumours as a separate entity within this group of sarcomas. © 1998 John Wiley & Sons, Ltd.
Human Patient Simulation: Teaching Students to Provide Safe Care

The use of human patient simulation as a teaching methodology for nursing students has become popular. Using human patient simulation effectively demands paying careful attention to the details of the simulation, debriefing, and evaluation processes. Our experience in designing simulation experiences and evaluating student behaviors confirms the resource-intensive nature of human patient simulation and the need for clear, measurable objectives. When used properly, human patient simulation offers a unique opportunity to teach nursing students important patient safety principles.
Year : 2007 On the chain rule for the divergence of BV-like vector fields : applications , partial results

We discuss the problem of computing the distributional divergence of a vector field of the form h(w)B, where h is a smooth scalar function and B is a BV vector field, knowing the distributional divergence of all vector fields w_iB, where w_i are the components of w. We present partial results on this problem, conjectures, and links with other problems related to the SBV regularity of solutions of Hamilton-Jacobi equations and systems of conservation laws, and a conjecture recently made by Bressan ON THE CHAIN RULE FOR THE DIVERGENCE OF BV LIKE VECTOR FIELDS: APPLICATIONS, PARTIAL RESULTS, OPEN PROBLEMS LUIGI AMBROSIO, CAMILLO DE LELLIS, JAN MALÝ