Miracle-dz/UniFAR-FTUs huggingface dataset:
Long‐term effects of microsurgical varicocelectomy on pain and sperm parameters in clinical varicocele patients with scrotal pain complaints

We aimed to investigate the long‐term effects of microsurgical varicocelectomy on pain improvement and sperm parameters in patients with varicocele‐related pain. A total of 72 patients who had undergone microsurgical subinguinal varicocelectomy because of varicocele with scrotal pain between 2004 and 2009 were included in the study. The patients were grouped according to the presence or absence of pain following surgical treatment. The patients expressing a decrease in frequency and severity of pain or minimal fullness sense were included in the pain‐positive group. The mean follow‐up period was 54.4 ± 18.06 months. There was left‐sided varicocele in 80.3% of patients, while 19.7% had bilateral varicocele. In our study, complete success rate (Visual Analog Scale: 0–1) was found to be 79.2% (57/72), while failure (complete and partial failure) rate was 20.8% (15/72), and a significant difference was found (P < 0.05). Microsurgical subinguinal varicocelectomy is a reliable approach for clinically varicocele patients with scrotal pain complaints. Regardless of the type of pain, varicocelectomy significantly decreases pain. The success of the treatment is not related to the degree of varicocele.
Motives and Decisions for and Against Having Children Among Nonheterosexuals and the Impact of Experiences of Discrimination, Internalized Stigma, and Social Acceptance

Same-sex parents are increasingly a topic of public discourse. A growing number of homosexuals openly speak about their desire to have children or are already living together in different family constellations. The current study examined the decisions for or against having children and the motivations behind those decisions among nonheterosexuals living in Germany. A sample of 1,283 nonheterosexuals participated by means of an online survey. As some nonheterosexual individuals do not identify themselves with a male or female gender identity, a third category, “gender different,” was generated. Motives for (not) having children, perceptions of social acceptance, experiences of discrimination in relation to one's sexual orientation, and levels of internalized stigma were taken into account regarding their influence on the decision about parenthood. Most respondents (80%) reported that they did not have children. However, among this group, 43% stated that they had decided to have children later in their lives, 24% were undecided, and 11% had already decided against having children. The most important influences on the decision of whether to have children were respondents’ age and their desire for emotional stabilization. Negative experiences as a result of sexual orientation and internalized stigma had no impact on the decisions regarding parenthood.
Predictors of Prejudice Against Lesbians and Gay Men in Jamaica

Jamaica has acquired an international reputation for strong antigay prejudice, incidents of antigay violence, and outspoken, antigay public figures. In recent years, national and international gay rights groups have attempted to improve this situation. However, these efforts have not been based on an empirical analysis of the factors underlying Jamaican antigay bias, which is essential for developing effective prejudice-reducing strategies. Using data collected in two large-scale national surveys in 2011 and 2012 (N 2011 = 997, N 2012 = 945), we investigated predictors of Jamaican antigay prejudice, including age, gender, religious affiliation, education, income, and a preference for dancehall music. We also examined changes in reported antigay bias between 2011 and 2012 after accounting for other predictors. All proposed variables predicted some aspect of antigay prejudice, though sometimes in unexpected ways. Male gender emerged as a particularly important predictor. We discuss the strengths and limitations of our design and the implications of our findings for prejudice-reduction strategies in Jamaica.
Comparison of infliximab and ustekinumab for the treatment of moderate-to-severe psoriasis: an indirect comparison meta-analysis

Correspondence: Tao Fan Global Health Outcomes, Merck & Co, Inc., One Merck Drive, WS2E-76, Whitehouse Station, NJ, USA Tel +1 908 423 4627 Fax +1 908 735 1688 Email tao.fan@merck.com Objectives: As no direct comparisons have been made between infliximab and ustekinumab, the present study’s aim was to estimate these drugs’ relative efficacy in the treatment of moderate-to-severe psoriasis. Methods: Eleven randomized controlled trials of infliximab 5 mg/kg and ustekinumab 45 mg or 90 mg, reporting Psoriasis Area and Severity Index (PASI) 75 and PASI 90 end points, were identified from a systematic literature review. Of these, five were excluded because they had inappropriate intervention (n = 1), inappropriate patient population (n = 3), or a small sample size (n = 1). Ultimately, six studies were included in the networks. Log odds ratio (OR) of achieving PASI 75 or PASI 90 was used as the treatment effect in fixedand random-effects mixed treatment comparison meta-analysis. Results: Based on the results of the random-effects model, when compared to infliximab 5 mg/kg, the OR of ustekinumab 90 mg and ustekinumab 45 mg achieving a PASI 75 following 12 weeks of treatment was 0.57 CrI (0.19, 1.29) and 0.44 (0.15, 0.99), respectively. Similarly, the odds of achieving PASI 90 was 0.77 (0.09, 2.70) for ustekinumab 90 mg and 0.63 (0.07, 2.20) for ustekinumab 45 mg. Infliximab 5 mg/kg had the highest probability of being the most effective of all treatments considered, in attaining a PASI 75 (92%) and PASI 90 response (76%). Ustekinumab 90 mg had the highest probability of being ranked second in attaining a PASI 75 (84%) and PASI 90 response (62%). Results from the randomand fixed-effects models were consistent. Conclusion: A greater proportion of patients with plaque psoriasis are expected to achieve a PASI 75 or PASI 90 response when treated with infliximab 5 mg/kg than with ustekinumab 90 mg or 45 mg.
Do Children With Gender Dysphoria Have Intense/Obsessional Interests?

This study examined whether children clinically referred for gender dysphoria (GD) show increased symptoms of autism spectrum disorder (ASD). Circumscribed preoccupations or intense interests were considered as overlapping symptoms expressed in GD and ASD. In gender-referred children (n = 534; 82.2% male) and their siblings (n = 419; 57.5% male), we examined Items 9 and 66 on the Child Behavior Checklist, which measure obsessions and compulsions, respectively. Non-GD clinic-referred (n = 1,201; 48.5% male) and nonreferred (n = 1,201; 48.5% male) children were also examined. Gender-referred children were elevated compared to all other groups for Item 9, and compared to siblings and nonreferred children for Item 66. A gender-related theme was significantly more common for gender-referred boys than male siblings on Item 9 only. A gender-related theme was not significantly more common for gender-referred girls compared to their female siblings on either item. The findings for Item 9 support the idea that children with GD show an elevation in obsessional interests. For gender-referred boys in particular, gender-related themes constituted more than half of the examples provided by their mothers. Intense/obsessional interests in children with GD may be one of the factors underlying the purported link between GD and ASD.
Feasibility, Acceptability, and Initial Efficacy of an Online Sexual Health Promotion Program for LGBT Youth: The Queer Sex Ed Intervention

Lesbian, gay, bisexual, and transgender (LGBT) youth experience multiple sexual health inequities driven, in part, by deficits in parental and peer support, school-based sex education programs, and community services. Research suggests that the Internet may be an important resource in the development of sexual health among LGBT youth. We examined the feasibility of recruiting youth in same-sex relationships into an online sexual health intervention, evaluated intervention acceptability, and obtained initial estimates of intervention efficacy. LGBT youth (16 to 20 years old) completed Queer Sex Ed (QSE), an online, multimedia sexual health intervention consisting of five modules. The final sample (N = 202) completed the pretest, intervention, and posttest assessments. The primary study outcomes were sexual orientation identity and self-acceptance (e.g., coming-out self-efficacy), sexual health knowledge (e.g., sexual functioning), relationship variables (e.g., communication skills), and safer sex (e.g., sexual assertiveness). Analyses indicated that 15 of the 17 outcomes were found to be significant (p < .05). Effect sizes ranged from small for sexual orientation (e.g., internalized homophobia) and relationship variables (e.g., communication skills) to moderate for safer sex (e.g., contraceptive knowledge) outcomes. This study demonstrated the feasibility, acceptability, and initial efficacy of QSE, an innovative online comprehensive sexual health program for LGBT youth.
Peer Nominations as Related to Academic Attainment, Empathy, Personality, and Specialty Interest

Purpose To test the hypotheses that peer nomination is associated with measures of (1) academic performance, (2) empathy, (3) personality, and (4) specialty interest. Method In 2007–2008, 255 third-year medical students at Jefferson Medical College were asked to nominate classmates they considered the best in six areas of clinical and humanistic excellence. The authors compared students who received nominations with those who did not, analyzing differences in academic performance, personality factors (empathy as measured by the Jefferson Scale of Empathy and personality qualities as measured by the Zuckerman–Kuhlman Personality Questionnaire), and specialty interests. Results A comparison of the 155 students who received at least one peer nomination with the 100 students who received none found no significant difference in scores on objective examinations; nominated students, however, were rated significantly higher in clinical competence by faculty in six core third-year clerkships. Nominated students were also significantly more empathic and “active. ” In addition, a larger proportion of nominated students choose “people-oriented” (rather than “technology- or procedure-oriented”) specialties. Conclusions These results confirmed the hypotheses that peer nomination can predict clinical competence, empathy and other positive personal qualities, and interest in people-oriented specialties. Thus, in the assessment of medical students, peer nomination holds promise as a valid indicator of positive dimensions of professionalism.
Catalase improves motility, vitality and DNA integrity of cryopreserved human spermatozoa

Cryopreservation of human spermatozoa offers a pre‐therapeutic possibility of preserving progenity in patients with testicular tumours. We aimed to investigate effects of cryopreservation and addition of catalase on sperm motility, vitality and DNA integrity in fresh and swim‐up spermatozoa. Semen samples were collected from 50 fertile men. Each sample was divided into two parts. First part was subdivided into two equal aliquots: both cryopreserved with and without catalase. The second part was subdivided into two equal aliquots: both processed by swim up and then cryopreserved with or without catalase. Semen analyses, sperm vitality and sperm DNA integrity were performed. Sperm concentration showed significant decrease while percentage of progressive motility, sperm vitality and % of DNA damage showed significant increase in processed and cryopreserved processed samples when compared with fresh and cryopreserved fresh samples. There was no significant difference in sperm concentration while there was significant increase in % of progressive motility and sperm vitality and % of DNA damage showed significant decrease in samples with catalase when compared with samples without catalase (either fresh or processed). Catalase supplementation (fresh and processed) during cryopreservation results in better post‐thawing percentage of progressive motility and percentage of sperm vitality and improved DNA integrity.
Around Consensual Nonmonogamies: Assessing Attitudes Toward Nonexclusive Relationships

Consensual nonmonogamy is a term used to describe intimate romantic relationships that are sexually and/or emotionally nonexclusive. The present study examined the social norms that are violated by different forms of consensual nonmonogamy and the negative judgments that result. We asked 375 participants to rate hypothetical vignettes of people involved in one of five relationship types (monogamy, polyamory, open relationship, swinging, and cheating) on items related to relationship satisfaction, morality, and cognitive abilities. The monogamous couple was perceived most favorably, followed by the polyamorous couple, then the open and swinging couples who were rated equally. Participants judged the cheating couple most negatively. Although social norms of sexual and emotional monogamy are important, we conclude that the aspect that has the most effect on judgments is whether the relationship structure has been agreed to by all parties.
A New Measure of the Perceived Influence of Sexually Explicit Online Media on the Sexual Behaviors of Men Who Have Sex With Men

Men who have sex with men (MSM) frequently consume sexually explicit online media (SEOM), yet little is known about its influence on their sexual behaviors. We describe a sequence of four studies to develop and psychometrically validate a measure of the perceived influence of sexually explicit online media (PI-SEOM) on the sexual behaviors of MSM. Study 1 involved qualitative interviews (N = 28) and a quantitative survey (N = 100) to develop a preliminary measure. Using an Internet sample of MSM (N = 1,170), we assessed its factor structure and reliability in Studies 2 and 3 as well as convergent validity and associations with HIV-related sexual risk in Study 4. Based on findings the measure was divided into two subscales: influences on (1) self and (2) other MSM. Factor analyses confirmed a two-factor model for each subscale, measuring perceived influences on (a) general sexual scripts and (b) condomless sex scripts. Survey results indicated that the more men perceived SEOM influencing their own condomless sex scripts, the more likely they were to report engaging in sexual risk behaviors. The developed measure holds promise for assessing the influence of SEOM on the sexual behaviors of MSM and may prove useful for HIV-prevention research.
Adolescents and Pornography: A Review of 20 Years of Research

The goal of this review was to systematize empirical research that was published in peer-reviewed English-language journals between 1995 and 2015 on the prevalence, predictors, and implications of adolescents’ use of pornography. This research showed that adolescents use pornography, but prevalence rates varied greatly. Adolescents who used pornography more frequently were male, at a more advanced pubertal stage, sensation seekers, and had weak or troubled family relations. Pornography use was associated with more permissive sexual attitudes and tended to be linked with stronger gender-stereotypical sexual beliefs. It also seemed to be related to the occurrence of sexual intercourse, greater experience with casual sex behavior, and more sexual aggression, both in terms of perpetration and victimization. The findings of this review need to be seen against the background of various methodological and theoretical shortcomings, as well as several biases in the literature, which currently precludes internally valid causal conclusions about effects of pornography on adolescents.
A Qualitative Exploration of Factors That Affect Sexual Desire Among Men Aged 30 to 65 in Long-Term Relationships

Few empirical studies have explored men’s experiences of sexual desire, particularly in the context of long-term relationships. The objective of the current study was to investigate the factors that elicit and inhibit men’s sexual desire. Semistructured interviews were conducted with 30 men between the ages of 30 and 65 (average age 42.83 years) currently in long-term heterosexual relationships (average duration 13 years 4 months). Analysis was conducted using grounded theory methodology from the interpretivist perspective. A total of 14 themes and 23 subthemes were identified to capture men’s descriptions of eliciting and inhibiting factors of their sexual desire. The six most integral themes are presented in the current article, all of which reflect the perspectives of the majority of participants, regardless of age or relationship duration, specifically (a) feeling desired, (b) exciting and unexpected sexual encounters, (c) intimate communication, (d) rejection, (e) physical ailments and negative health characteristics, and (f) lack of emotional connection with partner. The findings suggest that men’s sexual desire may be more complex and relational than previous research suggests. Implications for researchers and therapists are discussed.
Consequences of Casual Sex Relationships and Experiences on Adolescents’ Psychological Well-Being: A Prospective Study

Casual sexual relationships and experiences (CSREs) are still considered to be detrimental to the psychological well-being of youth even though findings remain inconclusive. Most studies have focused on emerging adulthood. Using a prospective design based on a representative sample of high school students in the province of Québec, we measured sexually active adolescents’ (N = 2,304) psychological well-being six months after engaging in these relationships while controlling for prior well-being. We analyzed two forms of CSREs, friends with benefits (FWB) and one-night stand (ONS) relationships, as well as levels of sexual intimacy. The results show that CSREs had a small impact (small effect sizes) on subsequent psychological well-being, especially among girls; FWB relationships involving penetrative contact increased girls’ psychological distress and both their alcohol and drug consumption. ONSs including sexual touching increased girls’ psychological distress and their drug use. None of the CSREs influenced boys’ psychological well-being. The findings underscored the importance of using caution when arguing that CSREs are detrimental or harmless to the psychological well-being of adolescents. The results also highlight the importance of taking into account gender and forms of CSREs in prevention and health interventions.
Dating Infidelity in Turkish Couples: The Role of Attitudes and Intentions

Studies on dating infidelity have mostly been carried out in individualistic, Western cultures and have tended to investigate either attitudes or intentions toward infidelity in isolation from each other. The current study therefore investigated dating infidelity in a more collectivist, predominantly Muslim culture. Informed by the theory of planned behavior, it tested intentions as a potential mechanism that might account for the association between attitudes toward infidelity and reported infidelity. In doing so, the role of gender and infidelity history was also investigated in regard to attitudes and intentions toward infidelity. A sample of 420 college students (292 women) completed the Turkish versions of the Attitudes Towards Infidelity Scale and the Intentions Towards Infidelity Scale. A 2 (gender) × 2 (infidelity history: yes, no) multivariate analysis of variance (MANOVA) revealed main effects but no interaction effect. Men compared to women and cheaters compared to noncheaters reported more favorable attitudes and intentions toward infidelity. Moreover, intentions toward infidelity fully and partly mediated the association between attitudes toward infidelity and infidelity for women and men, respectively. Findings are interpreted in light of dating infidelity research, with a focus on universal and culturally specific aspects. Recommendations are made for future research.
“Gay Equals White”? Racial, Ethnic, and Sexual Identities and Attitudes Toward LGBT Individuals Among College Students at a Bible Belt University

While past research has certainly explored a variety of correlates of attitudes toward lesbian, gay, bisexual, and transgender (LGBT) individuals, the current study is among the first in an emerging line of inquiry that examines attitudes toward each of these groups separately utilizing an intersectional framework with special attention to racial, ethnic, and sexual identities. Using a college sample of students from the Bible Belt of the United States (N = 1,940), I investigated the roles of racial and ethnic identities (Caucasian/White, African American/Black, Asian/Pacific Islander, Native American/Alaskan Native, other race, and Hispanic/Latinx), religiosity, patriarchal gender norms, parental perspectives, and the intersections among these identities and experiences as they relate to attitudes toward LGBT individuals among heterosexual (n = 1,551) and LGB respondents (n = 389). This moves beyond explorations of White heterosexual people’s attitudes about “homosexuals” (i.e., away from a focus only on gayness and Whiteness) and expands to include non-White LGB people’s LGBT attitudes. Overall, results indicate that racial, ethnic, and sexual identities play a significant role in southern college students’ LGBT attitudes, and these patterns are further complicated by interacting cultural experiences with religiosity, patriarchy, and family dynamics. Campus policy and program implications are provided.
Sexual Risk Behaviors and Perceptions of Men Who Go to Gay Sex Parties in New York City: Comparisons Between Three HIV Groups

Men who have sex with men (MSM) who attend group-sex events often engage in risky sexual behaviors that contribute to the high human immunodeficiency virus (HIV) incidence among this population. We conducted an online survey with 211 New York City MSM who attended sex parties in the prior year and asked them to describe their behaviors and perceptions of risk. We compared responses from HIV-positive-undetectable men (n = 36), HIV-negative men on pre-exposure prophylaxis (PrEP; n = 62), and HIV-negative men never on PrEP (n = 113). In bivariate analyses, undetectable and on-PrEP men had been to more sex parties in the prior six months, had more anal sex partners there, and had higher rates of sexually transmitted infection (STI) diagnoses than men never on PrEP. Although less than the other groups, 43% of the presumably HIV-negative men never on PrEP reported condomless anal sex at a party in the prior six months. About half of participants agreed that, at sex parties, they made assumptions about others’ HIV status, that they sometimes took more risks than intended, and that the atmosphere of these events was conducive to risk taking. Most disagreed that there was discussion of HIV status at sex parties. Implications for sexual health interventions are discussed.