Miracle-dz/UniFAR-FTUs huggingface dataset:
Use of a device to support standing during a physical activity program to improve function of individuals with disabilities who reside in a nursing home

Purpose. To demonstrate the feasibility of an innovative program of physical activity using a standing-support device targeted towards adult residents of a nursing home who are unable to transfer or stand independently. Method. Intervention study. Participants. Thirteen residents, age 82 ± 11 years, at the Beit Bayer Nursing Home, Jerusalem, Israel, who were unable to transfer or stand independently. Intervention. Eight-week observational period followed by 12-week physical activity performed while standing in a Standing-Support Device. Measurements. Manual Muscle Testing, joint range of motion, forward and lateral reach, time to stand independently, distance walked with a walker, Functional Independence Measure. Results. Compared to the observational period, significant post-intervention improvements were noted particularly in lower extremity muscle strength. Improvements in the Functional Independence Measure were noted in sphincter control, locomotion, mobility, motor score, and total score. Over 60% of those previously requiring assistance in standing became able to stand for an average of 1 min unassisted and walk an average of 14 m with a walker. Conclusion. A pilot program of physical activity using a Standing-Support Device is feasible in selected stance-disabled older adult nursing home residents. Participants showed evidence of muscle strength and functional improvement. Future studies of the device with a concurrent examination of healthcare costs, functional improvement, and staff burden, are recommended.
Novel molecular approach demonstrates that turbid river plumes reduce predation mortality on larval fish

Turbidity associated with river plumes is known to affect the search ability of visual predators and thus can drive ‘top‐down’ impacts on prey populations in complex ecosystems; however, traditional quantification of predator–prey relationships (i.e. stomach content analysis) often fails with larval fish due to rapid digestion rates. Herein, we use novel molecular genetic methods to quantify larval yellow perch (YP) in predator stomachs in western Lake Erie to test the hypothesis that turbidity drives variation in larval predation. We characterize predator stomach content DNA to first identify YP DNA (single nucleotide polymorphism) and then quantify larval YP predation (microsatellite allele counting) in two river plumes differing in turbidity. Our results showed elevated larval YP predation in the less turbid river plume, consistent with a top‐down impact of turbidity on larval survival. Our analyses highlight novel ecological hypothesis testing using the power of innovative molecular genetic approaches.
Formation of superoxide and hydroxy radicals in iron(II)-bleomycin-oxygen system: electron spin resonance detection by spin trapping.

The resultant spin adduct is usually a relatively stable nitroxide radical which can be characterized by electron spin resonance (ESR) method, and then it is possible to identify the radical R• from the ESR parameters in favorable cases. It has been suggested that the degradation of DNA in Fe(II)-bleomycin system is dependent on the oxidation of a Fe(II)-bleomycin-DNA complex, and that the formation of an oxygenlabile Fe(II)-bleomycin complex is related to DNA cleavage.4,5) Oxidation of the bleonrycinFe(II) complex by oxygen is expected to produce a variety of potentially reactive free-radical species which participate in the degradation of DNA. In this communication, the generation of O2 and -OH radicals from Fe(II)-bleomycin system in the presence of oxygen has been demonstrated by the production of the spin adducts of N-tertbutyl-a-phenylnitrone(BPN). BPN has the advantage of forming very stable spin adducts. Bleomycin-A2 purified was a gift from Nippon Kayaku Co. Ltd., and BPN was obtained from Aldrich Chemical Company. The reaction mixture for spin trapping consisted of 1: 1 bleomycinA2-Fe(II) complex(1.0~0.02 mM) and BPN
Coasts: Form, Process and Evolution

Preface 1. Introduction 2. Geological setting and materials 3. Coastal processes 4. Rocky coasts 5. Reef coasts 6. Beach and barrier coasts 7. Deltas and estuaries 8. Muddy coasts 9. Morphodynamics of coastal systems 10. Human activities and future coasts References Index.
Delivery of Antigen to CD40 Induces Protective Immune Responses against Tumors1

Ligation of CD40 induces maturation of dendritic cells (DC) and could be a useful target for vaccines. In this study, we have constructed two types of Ab-based vaccine constructs that target mouse CD40. One type is a recombinant Ab with V regions specific for CD40 and has defined T cell epitopes inserted into its C region. The other type is a homodimer, each chain of which is composed of a targeting unit (single-chain fragment variable targeting CD40), a dimerization motif, and an antigenic unit. Such proteins bound CD40, stimulated maturation of DC, and enhanced primary and memory T cell responses. When delivered i.m. as naked DNA followed by electroporation, the vaccines induced T cell responses against MHC class II-restricted epitopes, Ab responses, and protection in two tumor models (myeloma and lymphoma). Two factors apparently contributed to these results: 1) agonistic ligation of CD40 and induction of DC maturation, and 2) delivery of Ag to APC and presentation on MHC class II molecules. These results highlight the importance of agonistic targeting of Ag to CD40 for induction of long-lasting and protective immune responses.
Parameters affecting the course and results of delirium tremens treatment

The histories of 778 patients were analysed in respect of the course, type of treatment and lethality of delirium tremens. The lethality was highest in patients in the higher age range, those who were overweight and in spirit drinkers. The lowest mortality was in the patients treated with chlormethiazole (other drugs used included haloperidol and phenothiazines).
The crystal structure of apo-FtsH reveals domain movements necessary for substrate unfolding and translocation

The hexameric membrane-spanning ATP-dependent metalloprotease FtsH is universally conserved in eubacteria, mitochondria, and chloroplasts, where it fulfills key functions in quality control and signaling. As a member of the self-compartmentalizing ATPases associated with various cellular activities (AAA+ proteases), FtsH converts the chemical energy stored in ATP via conformational rearrangements into a mechanical force that is used for substrate unfolding and translocation into the proteolytic chamber. The crystal structure of the ADP state of Thermotoga maritima FtsH showed a hexameric assembly consisting of a 6-fold symmetric protease disk and a 2-fold symmetric AAA ring. The 2.6 Å resolution structure of the cytosolic region of apo-FtsH presented here reveals a new arrangement where the ATPase ring shows perfect 6-fold symmetry with the crucial pore residues lining an open circular entrance. Triggered by this conformational change, a substrate-binding edge beta strand appears within the proteolytic domain. Comparison of the apo- and ADP-bound structure visualizes an inward movement of the aromatic pore residues and generates a model of substrate translocation by AAA+ proteases. Furthermore, we demonstrate that mutation of a conserved glycine in the linker region inactivates FtsH.
Wide-band SIMO 1/spl times/2 measurements and characterization of outdoor wireless channels at 1.9 GHz

This paper aims at characterizing the spatial wireless channel at 1.9 GHz, based on a 1/spl times/2 measurement chain. A typical campus/residential area and an industrial area have been investigated. The measurement equipment is constituted by an 80-MHz transmitter at 1.9 GHz, located at the top of a building. At the receiver, two omnidirectional antennas are connected to a wide-band channel sounder through a switch in order to measure an estimate of the instantaneous vector channel. It is found that the Ricean K-factor and the delay spread are lognormally distributed, while the azimuth spread at the receive side follows a Gaussian distribution. The range dependence of various parameters are pointed out and compared with empirical models. The impacts of antenna spacing and array orientation on the channel correlation are highlighted and compared to theoretical simulation results. Finally, the cross-correlation properties between K-factor, delay spread, azimuth spread, and channel correlation are analyzed.
Monocyte and T-Cell Responses to Exercise Training in Elderly Subjects

Shimizu, K, Suzuki, N, Imai, T, Aizawa, K, Nanba, H, Hanaoka, Y, Kuno, S, Mesaki, N, Kono, I, and Akama, T. Monocyte and T-cell responses to exercise training in elderly subjects. J Strength Cond Res 25(9): 2565-2572, 2011—The purpose of this study was to examine the effects of exercise training on age-related impairment of immune parameters related to T-cell activation in elderly individuals. Twenty-four elderly subjects were assigned to an exercise training group (EXC: 3 men, 9 women; age 61-76 years) or a nonexercise control group (CON: 4 men, 8 women; age 62-79 years). Subjects in EXC participated in exercise sessions 2 d·wk−1 for 12 weeks. The training session included stretching and endurance exercise (10 minutes), resistance training comprised leg extension, leg press, hip abduction, and hip adduction using exercise machine and each subject's body weight. Subjects in CON maintained their normal physical activity levels during the study period. Blood samples were collected before and after the training period. Samples were measured for the numbers of leukocytes, lymphocytes, and monocytes, and for CD3+, CD4+, CD8+, CD28+CD4+, CD28+CD8+, TRL-4+CD14+, and CD80+CD14+ cells. The number of leukocytes, lymphocytes, monocytes, CD3+, CD4+, and CD8+ cells did not change after 12 weeks in either EXC or CON. The number of CD28+CD8+ cells increased significantly after training in EXC (p ≤ 0.05), although CON showed no significant change. In the EXC group, CD80+CD14+ cell counts were significantly higher after training (p ≤ 0.05), but the TLR-4+CD14+ cell counts were unchanged. In the CON group, no significant alteration existed in TLR-4+CD14+ and CD80+CD14+ cell numbers. In conclusion, exercise training in elderly people is associated with increased CD28-expressing Tc cells and CD80-expressing monocytes. Therefore, exercise training might upregulate monocyte and T-cell-mediated immunity in elderly people.
Hostility and Guilt in Obsessive-Compulsive Neurosis

Summary The enquiry relates to the investigation of 30 cases of obsessive-compulsive neurosis with special reference to the phenomena of hostility and guilt as revealed through Foulds' Five Punitive Scales and the Thematic Apperception Test. Controls consisted of an equal number of subjects suffering from neurotic depression. Analysis reveals acting-out hostility and extrapunitive tendency in the experimental group. No significant difference was found in terms of guilt scores.
Europarl: A Parallel Corpus for Statistical Machine Translation

We collected a corpus of parallel text in 11 languages from the proceedings of the European Parliament, which are published on the web. This corpus has found widespread use in the NLP community. Here, we focus on its acquisition and its application as training data for statistical machine translation (SMT). We trained SMT systems for 110 language pairs, which reveal interesting clues into the challenges ahead.
Anti-Müllerian hormone concentrations in the follicular fluid of the preovulatory follicle are predictive of the implantation potential of the ensuing embryo obtained by in vitro fertilization.

CONTEXT The strong relationship between serum anti-Müllerian hormone (AMH) levels and the number of antral follicles supports the use of AMH measurements as a quantitative marker of the ovarian follicular status. Yet, it still is unclear whether the aptitude of an individual follicle to produce AMH reflects its reproductive competence. OBJECTIVE This study examined the possible relationship between serum or follicular fluid (FF) AMH concentrations and the fate of the ensuing oocytes and embryos obtained by in vitro fertilization-embryo transfer conducted in monodominant follicle cycles. DESIGN AND SETTING We conducted a prospective study at the University of Paris XI, Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale U782. PATIENTS Patients included 118 infertile in vitro fertilization-embryo transfer candidates. INTERVENTIONS Concentrations of AMH, progesterone, and estradiol were measured in the serum on cycle d 3 and on the day of oocyte pickup (dOPU), and in FF. Cycles were sorted into three sets of three distinct groups according to whether serum d 3, serum dOPU, and FF AMH concentrations were 30th centile or below (low AMH), between the 31st and the 70th centiles (average AMH), or above the 70th centile (high AMH) of measurements. MAIN OUTCOME MEASURE Clinical pregnancy and embryo implantation rates were assessed. RESULTS Clinical pregnancy rates (5.7, 20.0, and 39.5%, respectively; P < 0.002) and embryo implantation rates (11.8, 30.8, and 65.4, respectively; P <0.001) were markedly different among the low, moderate, and high FF AMH groups but not among the serum (d 3 or dOPU) AMH groups. Fertilization rates and embryo morphology remained similar irrespective of AMH concentrations in the serum or in FF. Incidentally, FF AMH concentrations were negatively correlated with FF progesterone (r = -0.27; P <0.003) and FF estradiol (r = -0.21; P <0.02) concentrations. CONCLUSIONS Concentrations of AMH in the FF, but not in the serum, constitute a useful follicular marker of embryo implantation and are negatively related to FF progesterone and estradiol concentrations.
Feature extraction and representation for human action recognition

Human action recognition, as one of the most important topics in computer vision, has been extensively researched during the last decades; however, it is still regarded as a challenging task especially in realistic scenarios. The difficulties mainly result from the huge intra-class variation, background clutter, occlusions, illumination changes and noise. In this thesis, we aim to enhance human action recognition by feature extraction and representation using both holistic and local methods. Specifically, we have first proposed three approaches for the holistic representation of actions. In the first approach, we explicitly extract the motion and structure features from video sequences by converting the video representation into a 2D image representation problem; In the second and third approaches, we treat the video sequences as 3D volumes and propose to use spatio-temporal pyramid structures to extract multi-scale global features. Gabor filters and steerable filters are extended to the video domain for holistic representations, which have been demonstrated to be successful for action recognition. With regards to local representations, we have firstly done a comprehensive evaluation on the local methods including the bag-of-words (BoW) model, sparse coding, match kernels and classifiers based on image-to-class (I2C) distances. Motivated by the findings from the evaluation, we have proposed two distinctive algorithms for discriminative dimensionality reduction of local spatio-temporal descriptors. The first algorithm is based on the image-to-class distances, while the second explores the local Gaussians. We have evaluated the proposed methods by conducting extensive experiments on widely-used human action datasets including the KTH, the IXMAS, the UCF Sports, the UCF YouTube and the HMDB51 datasets. Experimental results show the effectiveness of our methods for action recognition.
VALES. II. The physical conditions of interstellar gas in normal star-forming galaxies up to z 0.2 revealed by ALMA

We use new Band 3 CO(1–0) observations taken with the Atacama Large Millimeter/submillimeter Array (ALMA) to study the physical conditions in the interstellar gas of a sample of 27 dusty main-sequence star-forming galaxies at 0:03 5σ in 26 sources. We find an average [Cii] to CO(1–0) luminosity ratio of 3500 ± 1200 for our sample that is consistent with previous studies. Using the [Cii], CO(1–0) and FIR measurements as diagnostics of the physical conditions of the interstellar medium, we compare these observations to the predictions of a photodissociation region (PDR) model to determine the gas density, surface temperature, pressure, and the strength of the incident far-ultraviolet (FUV) radiation field, G0, normalised to the Habing Field. The majority of our sample exhibit hydrogen densities of 4 < log n=cm3 < 5:5 and experience an incident FUV radiation field with strengths of 2 < logG0 < 3 when adopting standard adjustments. A comparison to galaxy samples at different redshifts indicates that the average strength of the FUV radiation field appears constant up to redshift z ~ 6:4, yet the neutral gas density increases as a function of redshift by a factor of ~100 from z = 0 to z = 0:2 that persists regardless of various adjustments to our observable quantities. Whilst this evolution could provide an explanation for the observed evolution of the star formation rate density with cosmic time, the result most likely arises from a combination of observational biases when using different suites of emission lines as diagnostic tracers of PDR gas.
Effects of Chicken Litter Storage Time and Ammonia Content on Thermal Resistance of Desiccation-Adapted Salmonella spp

ABSTRACT Broiler chicken litter was kept as a stacked heap on a poultry farm, and samples were collected up to 9 months of storage. Chicken litter inoculated with desiccation-adapted Salmonella cells was heat-treated at 75, 80, 85, and 150°C. Salmonella populations decreased in all these samples during heat treatment, and the inactivation rates became lower in chicken litter when storage time was extended from 0 to 6 months. There was no significant difference (P > 0.05) in thermal resistance of Salmonella in 6- and 9-month litter samples, indicating that a threshold for thermal resistance was reached after 6 months. Overall, the thermal resistance of Salmonella in chicken litter was affected by the storage time of the litter. The changes in some chemical, physical, and microbiological properties during storage could possibly contribute to this difference. Moisture and ammonia could be two of the most significant factors influencing the thermal resistance of Salmonella cells in chicken litter. Our results emphasize the importance of adjusting time and temperature conditions for heat processing chicken litter when it is removed from the chicken house at different time intervals.
Oral health in children undergoing liver transplantation.

AIMS To determine the prevalence of dental caries in children undergoing liver transplantation and to compare the plaque, gingivitis, and gingival overgrowth indices and oral mucosal lesions in children before and after liver transplantation. PATIENTS AND METHODS Patients undergoing liver transplantation at King's College Hospital were examined before transplantation, at 3 and 106 days post-transplantation. Healthy children from the Greenwich Health District, south-east London, were matched to the liver transplant patients by age, gender, socio-economic factors and the presence or absence of active dental caries. RESULTS Twenty-seven liver transplant patients (mean age: 7 years and 10 months; SD 3 years and 5 months) and 27 controls (mean age: 8 years and 6 months; SD 3 years and 7 months) were examined. The mean dmft and DMFT scores were 2.3 (SD 4.1) and 0.8 (SD 1.4), respectively, in the liver transplant patients, and 1.2 (SD 2.2) and 0.9 (SD 1.5), respectively, in the controls. There were no significant differences between either the mean plaque or gingivitis indices for the primary and permanent teeth in patients before and after transplantation. There were no significant differences between the liver transplant patients and the controls for either mean plaque or gingivitis indices at each examination time. Gingival overgrowth was present in 41% of liver recipients receiving cyclosporin with or without nifedipine, but not in the majority receiving tacrolimus at the final examination. Oral mucosal lesions were absent in both the patients and controls at each examination time. CONCLUSIONS The oral health of the children undergoing liver transplantation was inadequate. Funding and implementation of an oral health care programme must become a priority for all children before and after liver transplantation.
Naturally occurring ectopic growths in certain Xanthosoma and Begonia cultivars and the problem of leaf dorsiventral polarity.

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