Miracle-dz/UniFAR-FTUs huggingface dataset:
Effective time-domain antenna modeling based on impulse-matching method

This paper deals with analysis and optimization of wideband and ultra wideband antenna structures in the time domain by numerical solvers. In proposed method, signals at port and field probes at far-field region are used as powerful and effective markers. The method enables true time-domain computation with no susceptibility to difficulties connected with classical approach; hence is suitable especially for large structures with time-consuming analysis. Using of proposed method is demonstrated on the design of directional ultra wideband tapered slot antenna for ground penetrating radar application. Demonstration uses CST Microwave Studio.
Investigation the Relationship Between Strategic Orientation and Operational Performance in the Sudanese Service Firms

This study aims to examines the relationship between different dimensions of strategic orientation (market, service and learning) and operational performance constructs (flexibility, quality and cost) in the service sector in the Sudan, the study employed the quantitative methods via convenience sampling and self-administrated survey questionnaires were sent to 161 managers of service firms in Sudan response rate of 93 percent. Data from the study were collected analyzed using descriptive statistics, person correlation and path analysis through using (SPSS V. 23), (AMOS V. 25) in Structural Equation Modeling demonstrates some empirical supports to the model of this study. The Results of this study show that a partially significance between strategic orientation and operational performance in the Sudanese services firms. Market orientation and service orientation are a positively relationship with operational performance, while, the learning orientation not positive relationship with operational performance dimension. This study focuses only on the service sector. Also the data were only collected from single respondents in an organization. However, being the first study to explore the dimensions of strategic orientation and how those dimensions relate to operational performance efficiency, the study shapes the pathway for future research.
Presidential Address : Liquidity and Price Discovery

This paper examines the implications of market microstructure for asset pricing. I argue that asset pricing ignores the central fact that asset prices evolve in markets. Markets provide liquidity and price discovery, and I argue that asset pricing models need to be recast in broader terms to incorporate the transactions costs of liquidity and the risks of price discovery. I argue that symmetric information-based asset pricing models do not work because they assume that the underlying problems of liquidity and price discovery have been solved. I develop an asymmetric information asset pricing model that incorporates these e¡ects. THIS PAPER EXAMINES THE IMPLICATIONS of market microstructure for asset pricing. Both research areas focus on the behavior and evolution of asset prices, but the microstructure implications have been largely missing from the asset pricing literature. Such an omission is unimportant if asset pricing models work well in the sense of explaining the observed behavior of asset prices, but this is not the case.The proliferation of anomalies, momentum, and the changing cast of factors needed to explain even partially the behavior of asset prices all suggest that success is not yet within our grasp. I will argue in this paper that asset pricing ignores the central fact thatmarket microstructure focuses on: Asset prices evolve in markets. Markets have two important functionsFliquidity and price discoveryFand these functions are important for asset pricing. I will link these two concepts to our more basic constructs of risk and expected return, and I will suggest that asset pricing models need to be recast in broader terms to incorporate the transactions costs of liquidityand the risks of price discovery. I will argue that information is not symmetric nor is equilibrium revealing.The symmetric information-based asset pricing models do not work because they assume that the underlying problems of liquidity and price discovery have been completely solved. I suggest a di¡erent asset pricing framework of asymmetric information that requires rethinking THE JOURNAL OF FINANCE VOL. LVIII, NO. 4 AUGUST 2003 n Johnson Graduate School of Management, Cornell University. I would like to thank David Easley, Franklin Allen, Campbell Harvey, Gideon Saar, and John Campbell for helpful comments. These market functions, in turn, allow markets to play many di¡erent roles, among them that of allowing individuals to reallocate their asset holdings. This allocational a role results in risk sharing among investors, something that also may a¡ect asset prices.
Age-Related Differences in Timing With Breaks Louis Bherer

Two groups of participants differing in age were compared on a time production task during which timing was temporarily interrupted. Produced intervals lengthened with increasing delay before the break occurrence, and the effect was more pronounced in older than in younger adults. A reaction time response to the signal beginning the break period was required also. Older participants responded more slowly to this signal, but they benefited to a greater extent from a lengthening of the time preceding its presentation. These results suggest that performance of older participants is affected by attention sharing and preparation involved in timing with breaks.
Sustainability of Employee Productivity as a Presumption of Sustainable Business

The concept of the sustainable development popularized the reflection on resources allocation, but considering of sustainability of employee productivity is still in its infancy. Using the game theory model, we will analyze the influences and mechanisms that affect the individual as the unit of the sustainability of the company. In this paper, we will provide a new approach to an individual productivity and determine the boundaries of the employee’s workload using the game theory model. The model will sketch and determine the framework of long term and sustainable productivity of an individual, as the basis for the sustainable economic growth of the company. The final goal is to point out to the importance of respecting sustainability of productivity on the individual level. Provided framework could be used for both practical and theoretical application.
Three‐dimensional morphometric analysis of craniofacial shape in the unaffected relatives of individuals with nonsyndromic orofacial clefts: A possible marker for genetic susceptibility

Numerous studies have described altered patterns of craniofacial form in the unaffected relatives of individuals with nonsyndromic clefts. Unfortunately, results from such studies have been highly variable and have failed to provide a reliable method for differentiating “at‐risk” relatives from controls. In the present study, we compared craniofacial shape between a sample of unaffected relatives (33 females; 14 males) from cleft multiplex families and an equal number of age/sex/ethnicity‐matched controls. Sixteen x,y,z facial landmark coordinates derived from 3D photogrammetry were analyzed via Euclidean Distance Matrix Analysis, while 14 additional linear distances were analyzed via t tests. A subset of variables was then entered into a discriminant function analysis (DFA). Compared to controls, female unaffected relatives demonstrated increased upper facial width, midface reduction and lateral displacement of the alar cartilage. DFA correctly classified 70% of female unaffected relatives and 73% of female controls. Male unaffected relatives demonstrated increased upper facial and cranial base width, increased lower facial height and decreased upper facial height compared with controls. DFA correctly classified 86% of male unaffected relatives and 93% of male controls. In both sexes, upper facial width contributed most to group discrimination. Following DFA, unaffected relatives were assigned to risk/liability classes based on the degree of phenotypic divergence from controls. Results indicate that craniofacial shape differences characterizing unaffected relatives are partly sex‐specific and are in broad agreement with previous reports. These findings further suggest that a quantitative assessment of the craniofacial phenotype may allow for the identification of susceptible individuals within nonsyndromic cleft families. © 2008 Wiley‐Liss, Inc.
NEUROPHYSIOLOGY: Dynamic expression of glial cell line-derived neurotrophic factor after cerebral ischemia

The aim of this study was to understand the possible involvement of glial cell line-derived neurotrophic factor (GDNF) in rat brain ischemic injury by examining the expression and the cellular location of GDNF with molecular biological and morphological techniques. Expression of GDNF mRNA and protein was ®rst increased as early as 2 h after ischemia±reperfusion in peri-infarct cerebral cortex and striatum; it then declined, and showed a second increase at 72 h. Double staining con®rmed that the earlier peak of GDNF expression was of neuronal origin and the later peak of glial origin. Considering the neurotrophic characteristics of GDNF, our ®ndings suggest that elevated endogenous GDNF expression may have important roles in protection of ischemic injured neuronal cells. NeuroReport 11:1177±1183 & 2000 Lippincott Williams & Wilkins.
Non-steroidal anti-inflammatory agents and the gastrointestinal tract.

Non-steroidal anti-inflammatory drugs (NSAIDs) have had a bad press recently. The proliferation of these widely used agents has attracted the derogatory appellation 'me too'. Some, such as benoxaprofen, zomepirac, indoprofen and a controlled delivery indomethacin formulation ('Osmosin'), have been withdrawn because of concern about adverse drug effects including gastrointestinal bleeding (benoxaprofen) (Editorial, 1982) and bowel perforation ('Osmosin') (Day, 1983). Concern has been expressed for as long as NSAIDs have been available and there is little doubt that acute administration of many of them causes gastric erosions in animals and provokes microscopic bleeding in man. What remains controversial is whether there is a causative link between NSAID ingestion and peptic ulceration or important upper gastrointestinal haemorrhage. During the last two decades admissions to hospital and mortality rates for peptic ulcer have fallen in the UK (Coggon et al., 1981). This is mostly accounted for by changes among the young with little change in the mortality rate for women over 75 years of age. Aspirin consumption and smoking have declined and this may be a partial explanation of the overall trend but the elderly are major users of other NSAIDs and this might explain the differential ulcer mortality rate between old and young. However, the situation is complex. The elderly often have other diseases and take other drugs, more prescriptions are issued for NSAIDs to those under 65 years ofage than those over 65 and the number of prescriptions written has been steadily increasing in all age groups. There is therefore a need to question our fundamental assumptions about NSAIDs.
Performance Monitoring and Quality Teaching and Research in Private Universities in Uganda

This study assessed the influence of performance monitoring on quality teaching and research in private Universities in Uganda. Specifically, the study investigated how performance tracking, performance reviews, performance dialogue, and consequence management influence quality teaching and research. A positivist approach and cross sectional survey design were adopted for the study. Four chartered private Universities were selected using disproportionate stratified random sampling, basing on the foundation status. Data were collected from 181 lecturers, 5 Deans, 23 Heads of Department, 3 Quality Assurance officers, 3 Senior Officers from the National Council for Higher Education (NCHE) and 39 Student Leaders using a questionnaire, interviews, documents reviews and observation methods. Descriptive statistics and regression analyses, collaborated with content analysis were used to analyze the data. Study findings revealed a positive contribution of performance monitoring to quality teaching and research. The study concluded that staff performance monitoring practices in private universities are coercive and unsustainable in enhancing quality teaching and research. Therefore, the authors recommend that managers in the sampled private universities should use a variety of participatory-oriented performance monitoring mechanisms where targets are agreed upon, constructive feedback is provided on staff performance and staff are rewarding based on performance reviews. https://doi.org/10.26803/ijlter.17. 10.5
Extracellular HSP110 skews macrophage polarization in colorectal cancer

ABSTRACT HSP110 is induced by different stresses and, through its anti-apoptotic and chaperoning properties, helps the cells to survive these adverse situations. In colon cancers, HSP110 is abnormally abundant. We have recently showed that colorectal cancer (CRC) patients with microsatellite instability (MSI) had an improved response to chemotherapy because they harbor an HSP110 inactivating mutation (HSP110DE9). In this work, we have used patients' biopsies and human CRC cells grown in vitro and in vivo (xenografts) to demonstrate that (1) HSP110 is secreted by CRC cells and that the amount of this extracellular HSP110 is strongly decreased by the expression of the mutant HSP110DE9, (2) Supernatants from CRC cells overexpressing HSP110 or purified recombinant human HSP110 (LPS-free) affect macrophage differentiation/polarization by favoring a pro-tumor, anti-inflammatory profile, (3) Conversely, inhibition of HSP110 (expression of siRNA, HSP110DE9 or immunodepletion) induced the formation of macrophages with a cytotoxic, pro-inflammatory profile. (4) Finally, this effect of extracellular HSP110 on macrophages seems to implicate TLR4. These results together with the fact that colorectal tumor biopsies with HSP110 high were infiltrated with macrophages with a pro-tumoral profile while those with HSP110 low were infiltrated with macrophages with a cytotoxic profile, suggest that the effect of extracellular HSP110 function on macrophages may also contribute to the poor outcomes associated with HSP110 expression.
Aplikasi Metode Taguchi Untuk Menurunkan Tingkat Kecacatan Pada Produk Paving

Home Industry Putih Jaya is a company engaged in the paving blocks manufacturing which in producing paving certainly wanst to minimize any product defects. Known types of paving product that often occured is an easily cracked paving. An effort in the first stage to reduce the level of disability in this company is to identify the factors that affect product quality paving using fishbone diagram followed by the Taguchi method which is to determine the most influential factor and improve product quality paving so the defect rate can be decreased. From the data calculation with the fishbone diagram, there are six factors that influential. Among the six factors, those will be identified factor has the greatest influence resulting product quality deviates toward standards quality. Conclusion of the results showed that percentage of defect that occurs in the company initially around 4%, while by using the proposed improvement by Taguchi method decreases to 2%. The decreasing of defect percentage of defect means that the improvement of product quality is successfully. The factors the most influential factors to the paving is a drying process with the largest value of percent contribution in the amount of 34.5%.
Maximizing the impact of HIV prevention efforts: Interventions for couples

Despite efforts to increase access to HIV testing and counseling services, population coverage remains low. As a result, many people in sub-Saharan Africa do not know their own HIV status or the status of their sex partner(s). Recent evidence, however, indicates that as many as half of HIV-positive individuals in ongoing sexual relationships have an HIV-negative partner and that a significant proportion of new HIV infections in generalized epidemics occur within serodiscordant couples. Integrating couples HIV testing and counseling (CHTC) into routine clinic- and community-based services can significantly increase the number of couples where the status of both partners is known. Offering couples a set of evidence-based interventions once their HIV status has been determined can significantly reduce HIV incidence within couples and if implemented with sufficient scale and coverage, potentially reduce population-level HIV incidence as well. This article describes these interventions and their potential benefits.
Phase shift bandwidth and scan range in microstrip arrays by the element frequency tuning

In this paper, the far-field phase shift properties of microstrip patch antennas are investigated. It is shown that, similar to reflectarrays, the resonant nature of microstrip patches can be used to change the phase of the radiated field. This phase change can be caused by the dimensional change of the microstrip patch, or by a reactive loading of its cavity such as an aperture on its ground plane. However, the available phase shift is limited by the antenna impedance bandwidth. The problem is initially investigated for conventional patch antennas, determining the available phase shift range. It is then studied for a wideband E-slot microstrip antenna, showing a considerably larger phase shift range. Then, a micro-electro-mechanical (MEM) based ground plane membrane, activated by an electrode from below, is proposed to adaptively generate and control the required phase shifts. It provides a low loss, continuously variable phase shifter that can be used at high frequencies for beam scanning in small arrays
Pasture flock chicken cecal microbiome responses to prebiotics and plum fiber feed amendments

&NA; When prebiotics and other fermentation substrates are delivered to animals as feed supplements, the typical goal is to improve weight gain and feed conversion. In this work, we examined pasture flock chicken cecal contents using next generation sequencing (NGS) to identify and understand the composition of the microbiome when prebiotics and fermentation substrates were supplemented. We generated 16S rRNA sequencing data for 120 separate cecal samples from groups of chickens receiving one of 3 prebiotics or fiber feed additives. The data indicated that respective feed additives enrich for specific bacterial community members and modulate the diversity of the microbiome. We applied synthetic learning in microbial ecology (SLiME) analysis to interpret 16S rRNA microbial community data and identify specific bacterial operational taxonomic units (OTU) that are predictive of the particular feed additives used in these experiments. The results suggest that feed can influence microbiome composition in a predictable way, and thus diet may have indirect effects on weight gain and feed conversion through the microbiome.
Understanding the effective factors of knowledge management system usage in petroleum industry in developing economy

Knowledge management system (KMS), as a class of information system, is the backbone of organization that supports the implementation of KM practices. KMS usage contributes to competitive advantages. In the context of oil and gas industry in developing economy, there are reports of KMS usage failure; however, little knowledge is available about antecedents of KMS usage. The extant studies investigating the effective factors of KMS usage have yielded inconclusive findings. In oil and gas industry, there is a paucity of study on determinants of KMS usage. Our research addresses this issue by identifying the determinant factors of KMS usage in the context of oil and gas industry in developing economy, Pakistan. The study adopted cross-sectional survey involving 813 knowledge workers through clustered random sampling and 428 workable responses were returned. Drawing upon the theories of planned Behavior (TPB), Technology Acceptance Model (TAM) and Task Technology Fit (TTF), the study developed a conceptual model and tested it using SPSS and AMOS, Structural Equation Modeling (SEM). The initial conceptual model encompassed 11 hypotheses from which 7 hypotheses were accepted, while the rest were rejected. Thus, the constructs of commitment, subjective norms, perceived usefulness (PU), perceived ease of use (PEOU), Task-KMS-Fit, leadership and knowledge characteristics were accepted as determinants of KMS usage, while the variables of trust, socio-political influences, KMS-self-efficacy, and organizational structure were found to be insignificant. The results of this study have theoretical, practical, and methodological implications. This study bridges the knowledge gap between research and practice of KMS usage in oil and gas industry.
Continuous Dopaminergic Stimulation: Clinical Aspects and Experimental Bases

In patients with Parkinson disease, pulsatile administration of dopaminergic drugs is associated with motor fluctuations and dyskinesias. By contrast, treatments that provide more continuous dopaminergic stimulation are associated with less intense motor complications. This can be achieved by using drugs with longer half-lives, delayed release formulations, and routes of administration that permit continuous delivery. The mechanisms by which different modes of dopaminergic treatment (pulsatile or continuous) determine the motor response are not fully understood. However, the use of experimental models of parkinsonism has helped understand the motor complications associated with pulsatile dopamine replacement. These studies have provided important insights into the biochemical and molecular changes in the basal ganglia in response to continuous stimulation. In addition, these models have facilitated the development of new treatments that may stabilize the motor response and the biochemical alterations in the basal ganglia to provide more efficient forms of continuous dopaminergic stimulation in patients with Parkinson disease.
Fluctuating Attentional Demand in a Simulated Driving Assessment: The Roles of Age and Driving Complexity

Objective: The purpose of the study was to explore age differences in attentional demand in response to driving situations of varying complexity within the context of a simulated assessment protocol. It was hypothesized that as road complexity increased, an indicator of attentional demand (i.e., latency to respond to a secondary task) would increase and, independent of the road complexity, older adults would exhibit greater attentional demand in comparison with younger and middle-aged drivers. Methods: Drivers from 3 age categories (i.e., young, middle-aged, and older) completed an assessment protocol in a STISIM driving simulator (Systems Technology, Inc., Hawthorne, CA) during which participants responded to a series of strategically placed secondary tasks (i.e., peripheral detection tasks, PDTs). Situations where secondary tasks occurred were grouped according to whether they were straight-road, crossing-path, or lane-change events. Two global indices of driving safety as well as several cognitive measures external to the driving simulator were also collected. Results: The results supported the hypothesis in that complex driving situations elicited greater attentional demand among drivers of all ages. Older adults showed greater attentional demand in comparison to young and middle-aged adults even after controlling for baseline response time. Older drivers also scored poorer on a global measure of driving safety. Conclusions: The findings are highly consistent with the literature on road complexity and attention that show that increased driving complexity is associated with poorer performance on tasks designed to concurrently assess attention, an effect that is more pronounced for older drivers. The results point to intrinsic and extrinsic factors that contribute to motor vehicle collisions (MVCs) among older drivers. The relevance of these findings is discussed in relation to interventions and future research aimed at improving road safety.