Miracle-dz/UniFAR-FTUs huggingface dataset:
Novel Bunyavirus in Domestic and Captive Farmed Animals, Minnesota, USA

To the Editor: Xing et al. (1) conclude that evidence of infection with a severe fever with thrombocytopenia syndrome (SFTS)–like virus or Heartland-like virus (HRTV) was found in many captive large mammals from much of Minnesota, raising the specter of widespread distribution of a novel pathogen. Although it is likely that HRTV can be found beyond the areas in northwestern Missouri, where it was discovered (2), we contend that this conclusion is not substantiated by the data presented by Xing et al., which were generated by an assay that was developed to diagnose SFTS virus infections in China (1,3). The study used an ELISA developed for an SFTS virus recombinant nucleocapsid protein that detects SFTS-reactive antibodies (3). The conclusions reached by Xing et al. are based on the assumption that the SFTS assay developed in China will cross-react with HRTV antibodies (1). This assumption remains unsupported because the SFTS assay has not been evaluated for cross-reaction with antibodies to other non-SFTS members of the genus Phlebovirus (1,3). In addition, it is well recognized that serologic tests, like the ELISA, are often group reactive (4), requiring neutralization tests to confirm antibody presence and provide specificity. Alternative explanations include the possibility that positive results from testing by Xing et al. may have been caused by cross-reaction with antibodies directed against other known tick-associated phleboviruses endemic to North America, such as Lone Star virus (5), which is not known to be pathogenic. In the absence of confirmatory data generated by an independent method, the report by Xing et al. (1) should be considered speculative. Reports suggesting substantial expansion in the geographic range of a pathogenic organism should be based on rigorously validated laboratory methods.
Factors identifying pigs predisposed to tail biting

Approximately 5% of pigs slaughtered in the UK have been tail-bitten, leading to welfare and production issues. Tail biting is sporadic and not all pigs tail bite. The aim of this study was to identify factors that are common in pigs that perform tail-biting behaviour, and that might be used in a predictive way to identify such animals. The behaviour of 159 pigs was observed in the post-weaning period. Pigs were weaned at 4 weeks of age. In the week prior to weaning and at 6 weeks of age each pig was individually tested in a tail chew test (tail chew test 1 and 2, respectively). The tail chew test involved recording the pig's behaviour directed towards two ropes, one of which had been soaked in saline solution and the other not. The production performance of the pigs was recorded from birth to 7 weeks of age. Time spent performing tail-biting behaviour correlated positively with time in contact with the rope in tail chew test 2 ( r = 0·224, P r = 0·248, P P P P P > 0·05). The results suggest that pigs that tail bite have some nutritional deficiency that results in performance of foraging behaviour that is expressed in intensive housing as ear/tail biting.
Little Botany: A Mobile Game Utilizing Data Integration to Enhance Plant Science Education

Mobile devices are rapidly becoming the new medium of educational and social life for young people, and hence mobile educational games have become an important mechanism for learning. To help school-aged children learn about the fascinating world of plants, we present a mobile educational game called Little Botany, where players can create their own virtual gardens in any location on earth. One unique feature of Little Botany is that the game is built upon real-world data by leveraging data integration mechanism. The gardens created in Little Botany are augmented with real-world location data and real-time weather data. More specifically, Little Botany is using real-time weather data for the garden location to simulate how the weather affects plants growth. Little Botany players can learn to select what crops to plant, maintain their own garden, watch crops to grow, tend the crops on a daily basis, and harvest them. With this game, users can also learn plant structure and three chemical reactions.
Mitral valve replacement and remodeling of the left ventricle in dilated cardiomyopathy with mitral regurgitation: initial results.

OBJECTIVE This study evaluated the effects of a new method of mitral valve replacement on left ventricular (LV) remodeling and heart failure functional class. METHODS Eight patients (6 men) with severe mitral regurgitation from end-stage dilated cardiomyopathy underwent surgery. Five patients were in functional class (FC) IV, 2 were in FC III and 1 was in FC III/IV. Age ranged from 33 to 63 years. Both the anterior and posterior leaflets of the mitral valve were divided into hemileaflets. The resultant 4 pedicles were displaced under traction toward the left atrium and anchored between the mitral annulus and an implanted valvular prosthesis. The beating heart facilitated ideal chordae tendineae positioning. RESULTS All patients survived and were discharged from the hospital. After a mean follow-up period of 6.5 months (1-12 m), 5 patients were in FC I; 2 in FC I/II; and 1 in FC II. The preoperative ejection fraction ranged from 19% to 30% (mean: 25.7 +/- 3.4 %), and the postoperative ejection fraction ranged from 21% to 40% (mean: 31.1 +/- 5.8%). Doppler echocardiography showed evidence of LV remodeling in 4 patients, including lateral wall changes and a tendency of the LV cavity to return to its elliptical shape. CONCLUSION This technique of mitral valve replacement, involving new positioning of the chordae tendineae, allowed LV remodeling and improvement in FC during this brief follow-up period.
Assessing the Impact of Complaints Management System in Hospitality Organizations in Egypt: A Customer-organization Perspective

The objectives of this research are to investigate the concept of complaints management, its significance, and to address the different approaches of implementing and dealing with the concept in hospitality operations in Egypt. The methodology employed for this research used both primary and secondary sources. The secondary data provided the theoretical framework for the research via a comprehensive literature review. The primary qualitative data were collected via semi-structured interviews over the phone addressing the different stages, issues, and approaches of complaints management system. The interviewed participants included operational customer service managers from a purposive sample of hotel companies operating in Egypt. The outcomes of this research emphasize the significance of attaining a proper complaints management system in hotel operations, point up the different stages of complaints process and scrutinize the customer-organization relationship. Finally, it encourages hospitality professionals to foster their vision and strategies as regard the development of complaints management system that supports and enhances their operational quality, and customers' and employees' retention schemes.
Pharmacokinetic profile of a 24-hour controlled-release OROS formulation of hydromorphone in the presence of alcohol

ABSTRACT Objective: The purpose of this study was to investigate the pharmacokinetic properties of a novel, once-daily, controlled-release formulation of hydromorphone (OROS* hydromorphone) in the presence of alcohol. * OROS is a registered trade name of ALZA Corporation, Mountain View, CA, USA Research design and methods: In a single-centre, open-label, four-treatment, four-period, four-sequence, crossover study, two groups of 24 healthy subjects (fasted or fed) were randomised to receive four single doses of OROS hydromorphone 16 mg with solutions of either 0%, 4%, 20% or 40% alcohol, and with a naltrexone block. Main outcome measures: Plasma samples taken predose and at regular intervals up to 48 h after dosing were assayed for hydromorphone concentrations; a mixed-effect analysis of variance was done on log-transformed data. Bioequivalence was concluded if 90% confidence intervals of treatment mean ratios were between 80% and 125%. Results: Plasma hydromorphone concentrations were slightly higher after dosing with all alcohol treatments in both the fasted and fed subject groups. Median Tmax values were between 12 and 16 h and ranges were similar for all treatments. Cmax values increased after alcohol compared with no alcohol, with the increase slightly lower in the fed state. The greatest mean increase in Cmax observed was 1.3-fold in the fasted state and 1.1-fold in the fed state. Confidence intervals were within 80–125% for AUC but were slightly higher for Cmax. Conclusions: The pharmacokinetics of once-daily OROS hydromorphone were only minimally affected by alcohol, with no dose dumping of hydromorphone. The results indicate that the controlled-release properties of this formulation are maintained in the presence of alcohol.
Determination of some phenolic compounds in Crocus sativus L. corms and its antioxidant activities study

It is well known that phenolic compounds are constituents of many plants. In this study, the total phenolics content in Crocus sativus L. corms in dormancy and waking stages were determined by the Folin-Ciocalteu method. Analysis was carried out by gas chromatography-mass spectrometry (GC-MS) after silylation by N-methyl-N-trimethylsilyl trifluroacetamide (MSTFA) + %1 trimethyl iodosilane (TMIS). Numerous compounds were detected and 11 compounds were identified. The highest phenolics content in waking corms was observed for gentisic acid (5.693 ± 0.057 μg/g) and the lowest for gallic acid (0.416 ± 0.006 μg/g); also these two phenolic compounds are the highest (0.929 ± 0.015 μg/g) and lowest (0.017 ± 0.001 μg/g) phenolics in dormant corms, respectively. The results from quantization and GC-MS analysis showed a high concentration of phenolic compounds in waking corms than the dormant stage. Furthermore, the radical scavenging activities of saffron corms were studied by 1,1-diphenyl-2-pycrylhydrazyl (DPPH) test and EC 50values were determined about 2055 ppm and 8274 ppm for waking and dormant corms, respectively.
CURRENT STATE OF SURGE TESTING INDUCTION MACHINES

Surge testing of motor coils has been an industry practice since J. L. Rylander published “A High Frequency Voltage Test for Insulation of Rotating Electrical Apparatus” in Transactions of the AIEE, in February of 1926. Since that time the use of surge testing to diagnose failing or damaged insulation in motors has advanced greatly. In 1926, the indication of a turn-turn insulation failure was the drop of the coil voltage amplitude as determined by a vacuum tube rectifier circuit using an apparatus the size of a large work bench with rotating spark gaps for switches and large step up transformers to charge large high voltage capacitors. Today’s instrumentation uses high-speed digitizers to observe the entire waveform. Instead of a work bench, a 50lb portable enclosure contains the entire instrument which includes small high voltage power supplies, power semiconductors for switching elements, small efficient high voltage capacitors and a complete Pentium class computer with color display. The principles of surge testing, the strength of the turn-turn insulation being tested, the motivation to perform the surge test, the required test voltages necessary to succeed with the test, the industry standards surrounding the technology and the modern diagnostic algorithms will be presented.
Effect of company size, liquidity and operational efficiency on bank profitability with problem credit risk as a moderating variable at commercial banks that are listed on the Indonesia Stock Exchange

This study aims to measure and analyze the influence of company size, liquidity and operational efficiency on bank profitability with problem credit risk as a moderating variable at commercial banks that are listed on the Indonesia stock exchange. The unit of analysis in this study is 30 commercial banks listed on the official website of Bank Indonesia for the period 2012-2016. The type of data used is panel data with data analysis using purposive sampling method. The results of the study found that the size of the company negatively affected profitability, liquidity did not affect profitability, operational efficiency negatively affected profitability, company size positively affected problem credit risk, liquidity did not affect problem credit risk, operational efficiency had a positive effect on problem credit risk. problem credit risk has a positive effect on profitability.
Impact of Marital Quality And Psychological Well‐Being On Parental Sensitivity

The purpose of this study was to determine the extent to which marital quality influences psychological well-being, thereby contributing to parental sensitivity to infant cues among first-time mothers and fathers; the effects of parental age and infant sex on parental sensitivity; and whether the determinants of parental sensitivity differ between first-time mothers and first-time fathers. Data collections were done in the homes of 71 married couples with healthy, first-born 3-month-old infants. The maternal regression equation accounted for 17% of the variance in parental sensitivity, with perceptions of the spouse's participation in family life and maternal age explaining the most variance. The paternal equation accounted for 6% of the variance, with psychological well-being the only significant predictor. The sex of the infant was not a significant predictor of parental sensitivity for either parent.
COMPLEMENTING CBT FOR DEPRESSED ADOLESCENTS WITH LEARNING THROUGH IN VIVO EXPERIENCE (LIVE): CONCEPTUAL ANALYSIS, TREATMENT DESCRIPTION, AND FEASIBILITY STUDY

Based on a behavior-analytic interpretation of the skills acquisition process, a rationale is presented for augmenting a currently available cognitive-behavioral treatment (The Adolescent Coping With Depression course: CWD-A) with a newly developed therapy focusing on the interpersonal interactions and learning occurring in-session (Learning through In-Vivo Experience: LIVE). A description of the practice of LIVE is offered and the results from an initial feasibility study are presented. Using a single-subject methodology, two groups each consisting of 5 adolescents with significant symptoms of depression received the treatment. The intervention consisted of 16 2-hour group sessions occurring over an 8-week period. The first 1-hour of each meeting was taken directly from the CWD-A manual. The second hour was based on the LIVE manual. The adolescents who completed the treatment (n = 8) improved from pretreatment to posttreatment and those who discontinued treatment (n = 2) did not. Improvements were maintained at 3 months follow-up. The treatment produced strong group cohesion and both adolescents and their guardians rated the intervention positively. These results provide initial evidence of the efficacy of complementing CWD-A with LIVE.
Murabahah Versus Bank Loan: Concept of Interest and Profit

The primary objective of this paper is to lucidly explicate on the concept of murabahah and bank loan as well as to clarify the likely ambiguities emanating from the practice of murabahah by Islamic banks and loan by conventional banks. Descriptive content analysis is employed by reviewing classical and modern literatures on the practice of murabahah. The findings indicate that, murabahah is used on sale in attaining profit rather than on sale. It is also shown that, murabahah is grounded by Shariah. Indeed, financial transactions under the explanation of Maqasid al-Shariah by Ibn Ashur is used theoretical framework which is directly or indirectly linked with the practice of murabahah. The result shows the concept of murabahah from Islamic banking is different from the concept of interest practiced by conventional banks. The finding further indicates that, the extra charge added at the initial time of purchase of a particular product is not prohibited in Islam, but failure to pay the agreed amount on the fixed date by the buyer is undeniably regarded as forbidden usury based on the reference to Q 2:275. It is reiterated that, that Islam is permits the standard sale of a particular product whereby a product is bought with a price and sold with an increased price. In conclusion, the paper has established the viability of the murabahah transaction as a mechanism in promoting Islamic financial system. It is recommended that Islamic banks should device more mechanisms such as interbank benchmark rate in order to practically demonstrate the authenticity of Islamic financial system in the contemporary time specifically in making murabahah compliant with Maqasid al-Shariah on financial transactions.
Adoption of Robots, Artificial Intelligence and Service Automation by Travel, Tourism and Hospitality Companies – A Cost-Benefit Analysis

Travel, tourism and hospitality companies have started to adopt robots, artificial intelligence and service automation (RAISA) in the form of chatbots, delivery robots, robot-concierge, conveyor restaurants, self-service information/check-in/check-out kiosks, and many others. Despite the huge advancements in social robotics, the research on robots in tourism has been extremely limited – a gap that is partially filled by this paper. It investigates the costs and benefits of the adoption of RAISA by travel, tourism, and hospitality companies (hotels, restaurants, event organisers, theme and amusement parks, airports, car rental companies, travel agencies and tourist information centres, museums and art galleries and others). Specifically the paper looks at how RAISA influence the competitiveness, service quality, human resource management, service operations processes and standards, hospitality facilities layout, operating costs and revenues, and investigates the conditions under which the adoption of RAISA would be of benefit of the company. The paper acknowledges that the adoption of RAISA is dependent on the labour and technology costs, customers’ readiness and willingness to be served by a robots, cultural characteristics of both customers and service providers, the technological characteristics of RAISA solutions and other factors. The paper elaborates on the practical challenges to be faced by tourist companies when introducing RAISA (e.g. related to resistance to change, reengineering of service processes) and provide recommendations to both tourism companies and robot manufacturers how to deal with these challenges.
RPGR: Role in the photoreceptor cilium, human retinal disease, and gene therapy

Cilia are specialized dynamic organelles extending from the surface of almost all mammalian cells. Since proteins and protein precursors are transported across the ciliary compartments via intraflagellar transport (IFT), mutations in genes encoding proteins that participate in IFT can cause a spectrum of different ciliopathies. Photoreceptors of the mammalian retina contain ciliary structures that connect the inner (IS) with the outer segments (OS). This structure, the connecting cilium (CC), serves as the only junction between OS and IS, the correct passage of proteins through the CC is crucial for the functioning and maintenance of the cells. Therefore, any impairment of the IFT leads to severe malfunction of photoreceptors, and may induce apoptosis ultimately leading to the degeneration of the retina. The Retinitis Pigmentosa GTPase Regulator (RPGR), which is located in the CC, participates in the IFT and interacts with a variety of proteins, including RPGRIP-1, CEP290, NPM, SMC1 and 3 and IFT88. However, the function of RPGR through its interaction with these proteins is not yet entirely understood. Mutations in the RPGR gene lead to X-linked Retinitis pigmentosa (XLRP), one of the most severe and early onset forms of RP. Gene therapy is considered a potential therapeutic option and is currently under investigation in several animal models of XLRP. However, some of the currently available mouse models are only partially suitable for the development of therapeutic strategies and the quest for more appropriate small animal models is still an issue.
The Impact of Behavioral and Economic Drivers on Gig Economy Workers

Problem definition: Gig economy companies benefit from labor flexibility by hiring independent workers in response to real-time demand. However, workers’ flexibility in their work schedule poses a great challenge in terms of planning and committing to a service capacity. Understanding what motivates gig economy workers is thus of great importance. In collaboration with a ride-hailing platform, we study how on-demand workers make labor decisions; specifically, whether to work and work duration. Our model revisits competing theories of labor supply regarding the impact of financial incentives and behavioral motives on labor decisions. We are interested in both improving how to predict the behavior of flexible workers and understanding how to design better incentives. Methodology/results: Using a large comprehensive data set, we develop an econometric model to analyze workers’ labor decisions and responses to incentives while accounting for sample selection and endogeneity. We find that financial incentives have a significant positive influence on the decision to work and on the work duration—confirming the positive income elasticity posited by the standard income effect. We also find support for a behavioral theory as workers exhibit income-targeting behavior (working less when reaching an income goal) and inertia (working more after working for a longer period). Managerial implications: We demonstrate via numerical experiments that incentive optimization based on our insights can increase service capacity by 22% without incurring additional cost, or maintain the same capacity at a 30% lower cost. Ignoring behavioral factors could lead to understaffing by 10%–17% below the optimal capacity level. Lastly, our insights inform the design of platform strategy to manage flexible workers amidst an intensified competition among gig platforms. Funding: This study was supported by The Jay H. Baker Retailing Center, The William and Phyllis Mack Institute for Innovation Management, The Wharton Risk Management and Decision Processes Center, and The Fishman-Davidson Center for Service and Operations Management. Supplemental Material: The online appendices are available at https://doi.org/10.1287/msom.2023. 1191 .
The microdistribution of the trichomycete Smittium culisetae in the hindgut of the black fly host Simulium vittatum

We examined the distribution of hyphae of the trichomycete fungus Smittium culisetae (Harpellales: Legeriomycetaceae) in the hindgut of a larval black fly (Simulium vittatum, cytospecies IS-7) by analyzing its prevalence and relative abundance. Hyphal prevalence was highest in the posterior colon (93.1%) and rectum (86.3%), with low prevalence (12.0%) in the anterior colon. Relative abundance of hyphae was highest in the posterior colon, followed by the rectum; relative abundance of hyphae in the anterior colon was lower. Hyphae of S. culisetae were not observed in the pylorus. We used a novel method of quantifying the relative abundance of S. culisetae in the host hindgut. The hindgut was observed with an ocular grid, and abundance was expressed as the ratio of grids occupied by hyphae to the number of grids occupied by hindgut.