Miracle-dz/UniFAR-FTUs huggingface dataset:
Risk of contrast-induced nephropathy in patients undergoing endovascular treatment of acute ischemic stroke

Background and purpose We report the incidence and risk factors for contrast-induced nephropathy after the use of iodinated contrast for endovascular treatment of acute ischemic stroke. Methods A retrospective chart review was performed in 194 consecutive patients who underwent endovascular treatment for acute ischemic stroke between January 2006 and January 2011. No patients were excluded from treatment for elevated creatinine (Cr). Each patient received approximately 150 ml intra-arterial non-ionic low-osmolar contrast agent (Optiray 320) during the endovascular procedure. Contrast-induced nephropathy (CIN) was defined according to the Acute Kidney Injury Network criteria as a relative increase of serum Cr 50% above the baseline or an absolute increase of 0.3 mg/dl at 48 h following the endovascular procedure. Results Of 194 patients (mean age 65±14 years), 52% were women (n=100) and 25% (n=48) were diabetic. Baseline Cr levels for 191 patients ranged between 0.4 and 2.7 mg/dl. Three patients on chronic hemodialysis had baseline Cr levels ranging between 5.3 and 6.1 mg/dl. Cr was ≤1.5 mg/dl in 163 patients (84%) and ≥ 1.5 mg/dl in 31 (16%). Three of the 191 patients (1.5%) developed CIN as noted from Cr measurements between baseline and within 48 h. One patient who developed an elevated Cr level had a known history of chronic renal insufficiency (Cr > 1.5 mg/dl) and two had baseline Cr levels within the normal range. An additional CT angiogram was obtained in 44 patients, none of which developed CIN. Female gender and diabetes were not associated with a higher risk of developing CIN. Conclusions The risk of developing CIN is low among patients with acute stroke who undergo emergency endovascular treatment. Treatment of acute stroke should be performed irrespective of Cr levels.
Importance of Yeasts in the Mammary Infection of the Cattle in the Region of Sidi M’Hamed Ben Ali, Wilaya of Relizane, Algeria

The mastitis is one of the principal pathologies in the dairy bovine exploitation. The majority of the cases are caused by bacteria, but there are also cases caused by fungi. The objective of our study was to evaluate the occurrence of these fungi in mammary glands of 39 cows (mastitic cows and clinically healthy cows) belonging to two types of farms (4 exploitations using manual milking and 3 exploitations with milking machine) in the area of Sidi M’hammed Ben Ali, Wilaya of Relizane and to assess some risk factors (the tubes of drug, animal excretions, goblets - milkers, the milker hands and the litter). For this purpose, 150 sample of milk and 94 swabs were carried out. Our results revealed the presence of a heavy load of fungi cells in healthy and in the mastistic milks; with a strong frequency of the Trichosporon sp. (43, 58%) followed by the Candida sp. (30.76%). The same yeasts were isolated from swabs.
Feline Tularemia on Nantucket Island, Massachusetts

of clinical microbiology and virology, particularly for the microorganisms that are not in a replication phase or not capable of replication in vitro or in vivo. Within the next couple of years, several PCR assays using unique sets of oligonucleotide primers probably will become the standard method for detecting and identifying specific microorganisms. Acknowledgements. This study was supported by the College of Veterinary Medicine and the Mississippi Agricultural and Forestry Experiment Station, Mississippi State University. This report is manuscript no. J-8079.
Predicting the Potential Market for Electric Vehicles

Forecasting the potential demand for electric vehicles is a challenging task. Because most studies for new technologies rely on stated preference (SP) data, market share predictions will reflect shares in the SP data and not in the real market. Moreover, typical disaggregate demand models are suitable to forecast demand in relatively stable markets, but show limitations in the case of innovations. When predicting the market for new products it is crucial to account for the role played by innovation and how it penetrates the new market over time through a diffusion process. However, typical diffusion models in marketing research use fairly simple demand models. In this paper we discuss the problem of predicting market shares for new products and suggest a method that combines advanced choice models with a diffusion model to take into account that new products often need time to gain a significant market share. We have the advantage of a relatively unique databank where respondents were submitted to the sam.
Estudio Descriptivo: Características Clínicas, Demográficas e Histopatológicas de Pacientes con Diagnóstico de Linfoma no Hodgkin.

INTRODUCCION: El linfoma no Hodgkin (LNH) es una neoplasia que proviene de celulas lin­focitarias con una amplia variabilidad de presentacion clinica e histologica. El objetivo del presente estudio fue establecer el perfil de las caracteristicas clinicas, demograficas e histo­patologicas de los pacientes con diagnostico de Linfoma No Hodgkin con el fin de describir la casuistica local, la sintomatologia, histopatologia y estadiaje en el momento del diagnostico de la enfermedad. METODO: Se realizo un estudio descriptivo retrospectivo en 223 pacientes con diagnostico de Linfoma No Hodgkin que acudieron al Servicio de Oncologia del hospital “Jose Carrasco Arteaga” durante el periodo de mayo 2009 a mayo de 2014. Se estudiaron las variables edad, sexo, localizacion del Linfoma, presencia de sintomas B, factores de riesgo, estadio en el mo­mento del diagnostico e histopatologia; se utilizo la estadistica descriptiva con frecuencias absolutas y relativas. RESULTADOS: La relacion hombre-mujer fue de 1.45:1, el grupo etario mas afectado fueron los adultos mayores (≥ 65 anos), el sintoma B de mayor frecuencia fue la perdida de peso (10.8%), la localizacion ganglionar fue la mas frecuentemente comprometida (60.1%), el Lin­foma Difuso de Celulas Grandes Inmunofenotipo B fue el mas frecuente (59%) y los factores de riesgo mas habituales fueron los antecedentes familiares de cancer (43%), gastritis cronica (32%) y consumo de tabaco (25.9%). CONCLUSIONES: La frecuencia de LNH fue mayor en adultos mayores, es una enfermedad que en el medio se diagnostica en etapas tempranas (I-A y I-B); el sintoma B mas frecuente fue la perdida de peso. La mayor parte de los resultados obtenidos en el estudio fueron se­mejantes a los disponibles a nivel mundial, regional y local; se considera que los datos son extrapolables. *DESCRIPTORES DeCS: LINFOMA NO HODGKIN, PREVALENCIA, SIGNOS Y SINTOMAS.
The experiences and perceptions of family planning of female Chinese asylum seekers living in the UK

Introduction Chinese family planning policy is unique. There is limited sex education and the state is highly influential. This has resulted in extremely wide coverage of contraception with long-acting methods being favoured. The Chinese constitute a large proportion of asylum applicants to the UK. This study examines how their experiences and decisions about family planning in the UK are shaped by their cultural background. Methods Data were drawn from 10 semi-structured qualitative interviews with female Chinese asylum seekers recruited through a family planning clinic in the UK. Results The increased autonomy provided by the UK system was appreciated by the participants. Choice of contraceptive method was influenced by traditional cultural beliefs and values, and the effect of hormonal contraception on menstruation was particularly concerning. Women arrived from China with little knowledge of contraception. Friends from a similar background were the most trusted source of advice. When transitioning from China to the UK unwanted pregnancies had occurred amongst unmarried women who had missed out on sex education while living in China. Conclusions Chinese societal and cultural practices continue to influence family planning decisions made within the UK. Culturally competent health strategies are needed to ensure Chinese immigrant women fully benefit from family planning within the UK.
Model of the short vacuum arc at collision free motion of ions

The 2D mathematical model of the short vacuum-arc discharge is developed that considers a hydrodynamic mode of electron motion and collision-free mode for motion of fast cathode ions in a 2D electric field. The model takes into consideration an angle distribution of ions on the cathode plasma boundary. A method of calculation of plasma density distribution in the gap is proposed. Two-dimensional distributions of discharge current density, plasma density and electric field in an external longitudinal magnetic field are calculated. It is shown that intersections of ion trajectories take place and a part of ion trajectories returns to the cathode. As the value of the external magnetic field decreases, the number of ion trajectories returning to the cathode increases and the number of ion trajectories reaching the anode decreases.
Rate of Speech Effects in Aphasia: Voice Onset Time

This study investigated the ability to produce appropriate voice onset time (VOT) contrasts under conditions of rate modulation in groups of nonfluent aphasic subjects, fluent aphasic subjects, and nonneurological controls. Acoustic analyses of the consonants [b d g p t k] produced in the context of the vowels [i e a o u] at two different rates of speech revealed that normal subjects' VOTs were significantly shorter at the fast rate of speech relative to the slow/normal rate, as expected. In addition, the rate change had a significantly greater effect on voiceless stops as compared to voiced and on velar consonants as compared to labials and alveolars. The nonfluent aphasic patients exhibited a similar pattern except that no differences in magnitude of rate-related changes were found across place of articulation. Further, similar to previous studies, the nonfluent aphasic patients produced voice and voiceless consonants with somewhat overlapping VOT distributions, indicating an impairment in temporal integration in these subjects. Finally, the fluent aphasic patients demonstrated a surprisingly aberrant pattern of results, with VOTs under th fast condition shorter than under the slow, but no differences in magnitude of change across place of articulation or voicing categories. The results are discussed in relation to the nature of speech production deficits in both nonfluent and fluent aphasic patients. Implications for remediation are considered.
Prediction of genetic polymorphisms of DNA repair genes XRCC1 and XRCC3 in the survival of colorectal cancer receiving chemotherapy in the Chinese population.

BACKGROUND/AIMS We aimed to detect the distribution of DNA repair genes XRCC1 and XRCC3 genotypes in the survival of colorectal cancer patients receiving chemotherapy in the Chinese population. METHODOLOGY The prospective study was conducted with 432 cases treated with 5-FU and oxaliplatin as first-line chemotherapy. All the patients were followed-up from May 2006 to May 2011 and 168 patients died during follow-up. XRCC1 and XRCC3 genotype polymorphisms were based upon the PCR-CTPP method. RESULTS It was shown that the XRCC1 Arg399Gln and XRCC3 Thr241Met gene polymorphisms were associated with increased death risk of colorectal cancer. Individuals carrying XRCC1 Gln/Gln, Thr/Met and Met/Met genotypes positively associated with 2.78-, 2.86- and 3.0-fold death risk of colorectal cancer. Moreover, the combination of XRCC1 399Gln allele and XRCC3 241Met allele showed a significantly strong association with death risk of colorectal cancer (OR=3.46, 95%CI=1.65- 5.48). CONCLUSIONS This study is first to report that the XRCC1 and XRCC3 gene polymorphisms are useful as a surrogate marker of clinical outcome in colorectal cancer with 5-FU/oxaliplatin combination chemotherapy in the Chinese population.
Being a Positive Bystander

As bystander approaches become increasingly prevalent elements of sexual and domestic violence prevention efforts, it is necessary to better understand the factors that support or impede individuals in taking positive action in the face of aggressive or disrespectful behavior from others. This study presents descriptive findings about the bystander experiences of 27 men who recently became involved in antiviolence against women work. More specifically, we describe the consistency with which respondents actively intervene in the speech or behavior of others, the strategies they use, and the factors they weigh as they deliberate taking action. Respondents report a complex and interrelated set of individual and contextual influences on their choices within bystander opportunities, which hold implications for both violence-specific models of bystander behavior and for prevention intervention development.
Plasmid-mediated transformation of Streptococcus mutans

Streptococcus mutans GS-5 was transformed to erythromycin resistance with streptococcal plasmid pVA736. Transformation frequencies were higher with plasmids reisolated from transformed GS-5 cells relative to plasmid originally derived from S. sanguis Challis.
Eye muscle nerves nuclear size in a breed of domestic rabbits with floppy ears.

In many wild species there is a correlation between the capacity for directional hearing and directional seeing, which is associated with the mobility of the eye balls. Among the breeds of domestic rabbits, there are some with pendulous, floppy external ears (e.g., Englische Widder, EW) that might limit directional hearing. The size of the brain stem nuclei in EWs has been determined and compared to rabbits with upright ears. In EW, the oculomotor nuclei are relatively larger than in the other breeds. Possibly, this indicates a compensation of a loss in directional hearing ability achieved through greater mobility of the eyes. At the same time, a variability of brain composition between the breeds, which is an intraspecific variability, is obvious.
NITRATE CONTAMINATION IN OREGON WELL WATER: GEOLOGIC VARIABILITY AND THE PUBLIC'S PERCEPTION 1

ABSTRACT: Approximately 4.5 million people in the United States who rely on well water are exposed to nitrate‐N concentrations exceeding the 10 mg/l standard. In this study in the Southern Willamette Valley in Oregon we reassessed nitrate‐N in rural wells sampled in 2000–2001, compared nitrate‐N concentrations among geological units, and surveyed residents about their perceptions of well water quality. Nitrate‐N concentrations were again sampled in 2002 and found to have increased significantly from the previous period. With rapid population growth in the area, the potential health risk in drinking well water that exceeds 10 mg/l nitrate‐N warrants continued public education. Nitrate‐N concentrations were found to be higher in the Holocene alluvium of the Willamette River and the Pleistocene sand and gravel post‐Missoula Flood deposits. Researchers conducting future studies may choose to stratify and monitor wells by geologic unit and by other parameters that estimate input of nutrients to the environment. Opinions differed between agricultural landowners and nonagricultural landowners with regard to the impact that agricultural fertilizers may have on water quality. Participants were supportive of a range of regulatory actions that might be used by homeowners or landowners to address ground water contamination. Given that the area is now designated a Groundwater Management Area, understanding local stakeholders’perceptions is critical and strategic and has the potential to help public agencies manage potential conflicts of opinion among stakeholders, build consensus, and help guide the approach to restoring ground water quality.
Relationship of Radiographic Osteoarthritis Severity with Treatment Outcomes after Imaging-Guided Knee Injections: A Prospective Outcomes Study

Abstract Introduction To be able to predict which patients are more likely to have a positive treatment outcome, the purpose of this study is 1: To compare outcomes after intra-articular corticosteroid knee injections with the Kellgren and Lawrence (KL) 5 and 3 grading systems for knee osteoarthritis, the Osteoarthritis Research Society International (OARSI) grading system and actual joint space measurements; and 2: To compare the reliability of these grading systems. Materials and Methods Knee radiographs of 117 patients who received intra-articular corticosteroid injections were independently evaluated by two radiologists blinded to the outcome. Evaluation included the KL5, KL3, OARSI systems and actual joint space widths. The numerical rating scale for pain was collected at baseline and along with the Patient’s Global Impression of Change on day 1, in week 1 and in month 1. The number of ‘improved’ patients was compared between the OA grades using the Chi-square test. Logistic regression determined which findings were predictive for improvement. Agreement was assessed using Kappa statistics and the intraclass correlation coefficient (ICC). Results Patients with OARSI grade 2 reported the highest rates of ‘improvement’ at all time points, which was significant on day 1 (p = 0.004). No relationship with improvement was found with KL5, KL3 or actual joint space measurements. Patients with OARSI grade 2 were 8 times more likely to report improvement on day 1 (p = 0.024). Reliability was best for joint space measurements (ICC = 0.812 – 0.882), followed by the OARSI. Conclusion The OARSI for joint space narrowing grade 2 (34 – 66 % narrowing) was linked with a better outcome on day 1 with trends in week 1 and month 1. The reliability of the OARSI was better than the KL5 or KL3 systems. Key Points OARSI grading of OA had better reliability than KL3 or KL5. OARSI grade 2 was related to a better treatment outcome. Neither KL grades nor joint space measurements were related to improvement. Citation Format Miletic I, Agten C, Sutter R et al. Relationship of Radiographic Osteoarthritis Severity with Treatment Outcomes after Imaging-Guided Knee Injections: A Prospective Outcomes Study. Fortschr Röntgenstr 2018; 190: 134 – 143
The Telehealth Divide: Disparities in Searching Public Health Information Online

This article explores e government inequalities to searching Medicare and Medicaid information online. Telehealth, a branch of e government, can bring public health service and insurance information to the citizen. The Centers for Medicare and Medicaid Services website, among others, has critical information for potential beneficiaries and recipients of services. Using Pew survey data and multivariate regression analysis we find people in most need of Medicare and Medicaid information online (the elderly and poor) are accessing it, and people with years of online experience are strong proponents of online searches. Despite being less likely to have broadband services, individuals in rural areas were not found to be less likely to search for information online. In conclusion, some disparities are narrowing as the elderly and poor in need of access to public health insurance are searching for it online. However, people without Internet access and experience (perhaps the oldest and poorest) remain disadvantaged with respect to accessing critical information that can link them to needed health care services.
Globus pallidus deep brain stimulation in dystonia

Globus pallidus deep brain stimulation (GPi‐DBS) is a useful alternative in the treatment of dystonia. Patients selected for GPi‐DBS were prospectively rated with the Unified Dystonia Rating Scale (UDRS). Also, “blinded” videotape assessments were performed. Eleven patients were identified. Compared with pre‐DBS scores, there were improvements in mean total UDRS score (15.3%) and in the following subscores: neck (18.18%), trunk (32.9%), arm(17.9%), and leg (19.9%). One patient developed a skin infection and erosion requiring surgical debridement. GPi‐DBS is a safe and effective treatment for generalized dystonia in patients who remained impaired, despite optimal medical therapy. © 2005 Movement Disorder Society
Evidence for constitutive neural cell proliferation in the adult murine hypothalamus

Compelling evidence suggests that the mammalian brain is capable of generating new neurons throughout adult life. While neurogenesis can be induced at various brain sites by exogenous cues, constitutive birth of new neurons has been unambiguously demonstrated within the subventricular zone (SVZ) of the lateral ventricles and the subgranular zone (SGZ) of the dentate gyrus. The lack of strong evidence that constitutive neurogenesis occurs elsewhere in the adult brain could be due to its exclusive restriction to the SVZ and SGZ or, for instance, to the inadequacy of the methods used to reveal new‐born neurons at other brain sites. By using intracerebroventricular (icv) delivery of the mitotic marker bromodeoxyuridine (BrdU) we demonstrate that new cells are born continuously and in substantial numbers in the adult murine hypothalamus and that many of these cells appear to differentiate into neurons as assessed by the expression of doublecortin (Dcx) and other neuronal fate markers. As compared to intraperitoneal (ip) BrdU injections, central BrdU infusion also uncovers a higher‐fold induction of hypothalamic cell proliferation by ciliary neurotrophic factor (CNTF). It appears that new cells are born throughout the hypothalamic parenchyma without an apparent restriction to a specific neurogenic layer, as seen in the SVZ. Thus, we provide evidence that the adult hypothalamus is constitutively neurogenic and that hypothalamic cell proliferation is highly responsive to mitogen action. J. Comp. Neurol. 505:209–220, 2007. © 2007 Wiley‐Liss, Inc.
AY-4166 Increases the Sensitivity of Insulin Secretion to Glucose in Isolated Perfused Rat Pancreas

To study the effect of a therapeutic dose (3 microM) of AY-4166 on the glucose-stimulated insulin secretion, the rat pancreas was perfused with 5 to 15 mM glucose. AY-4166 did not affect the basal insulin secretion at 5 mM glucose, and increased the first and second phases of insulin secretion stimulated by 7.5 to 15 mM glucose. The dose-response curve of the insulin secretion to glucose was shifted to the left side by AY-4166. These results suggest that AY-4166 ist not a stimulator releasing insulin independently of glucose concentrations, but a potentiator of insulin secretion.
Conceptual Design of Operation Strategies for Hybrid Electric Aircraft

Ambitious targets to reduce emissions caused by aviation in the light of an expected ongoing rise of the air transport demand in the future drive the research of propulsion systems with lower CO2 emissions. Regional hybrid electric aircraft (HEA) powered by conventional gas turbines and battery powered electric motors are investigated to test hybrid propulsion operation strategies. Especially the role of the battery within environmentally friendly concepts with significantly reduced carbon footprint is analyzed. Thus, a new simulation approach for HEA is introduced. The main findings underline the importance of choosing the right power-to-energy-ratio of a battery according to the flight mission. The gravimetric energy and power density of the electric storages determine the technologically feasibility of hybrid concepts. Cost competitive HEA configurations are found, but do not promise the targeted CO2 emission savings, when the well-to-wheel system is regarded with its actual costs. Sensitivity studies are used to determine external levers that favor the profitability of HEA.