Miracle-dz/UniFAR-FTUs huggingface dataset:
Vitamina D e doenças endocrinometabólicas

Atualmente, a insuficiencia/deficiencia de vitamina D tem sido considerada um problema de saude publica no mundo todo, em razao de suas implicacoes no desenvolvimento de diversas doencas, entre elas, o diabetes melito tipo 2 (DMT2), a obesidade e a hipertensao arterial. A deficiencia de vitamina D pode predispor a intolerância a glicose, a alteracoes na secrecao de insulina e, assim, ao desenvolvimento do DMT2. Esse possivel mecanismo ocorre em razao da presenca do receptor de vitamina D em diversas celulas e tecidos, incluindo celulas-β do pâncreas, no adipocito e no tecido muscular. Em individuos obesos, as alteracoes do sistema endocrino da vitamina D, caracterizada por elevados niveis de PTH e da 1,25(OH)2D3 sao responsaveis pelo feedback negativo da sintese hepatica de 25-OHD3 e tambem pelo maior influxo de calcio para o meio intracelular, que pode prejudicar a secrecao e a sensibilidade a insulina. Na hipertensao, a vitamina D pode atuar via sistema renina-angiotensina e tambem na funcao vascular. Ha evidencias de que a 1,25(OH)2D3 inibe a expressao da renina e bloqueia a proliferacao da celula vascular muscular lisa. Entretanto, estudos prospectivos e de intervencao em humanos que comprovem a efetividade da adequacao do status da vitamina D sob o aspecto "prevencao e tratamento de doencas endocrinometabolicas" sao ainda escassos. Mais pesquisas sao necessarias para se garantir o beneficio maximo da vitamina D nessas situacoes.
The effect of variations in bonding procedure on fracture resistance of dentin-bonded all-ceramic crowns.

: This in vitro study investigated the effect of dentinal bonding and ceramic etching procedures on the fracture resistance of all-ceramic crowns. These results were compared with the fracture resistance of similar crowns placed with a nonadhesive conventional cement. All results indicated that superior fracture resistance was obtained when dentinal bonding was incorporated into the luting procedure together with etching of the ceramic fitting surface and the use of resin-based luting material. The fracture resistance of specimens luted with such a procedure was significantly greater than that of specimens in which a conventional nonadhesive cement was used.
The Study of Psychiatric Problem of the Caregivers of Children with Disability

<국문요약> 본 연구는 일부지역 장애아동 양육자의 정신과적 문제를 알아보기 위해 우울증 지수를 검사하고 분석함 으로서 그 심각성을 확인하고 장애아동 양육자의 정신보건의 필요성을 알리기 위한 기초자료를 제공하는 데 목적이 있다. 본 연구는 2011년 8월부터 9월까지 경주 및 인근지역에서 지적장애아동과 지체장애아동을 둔 전업주부의 정신과적 문제를 알아보기 위해 양육 스트레스로 인한 우울증 정도를 알아보았다. 연구대상자는 3개의 치료기관 및 치료 관련기관에서 지적장애 또는 지체장애 아동을 양육하고 있는 부 모 각 20명씩을 대상으로 하였다. 우울증 평가도구는 한국형 우울증 검사(Korean Depression Scale; KDS) 를 이용하였다. 결과는 첫째, 지적장애아동과 지체장애아동 양육자 모두 우울증이 있는 것으로 나타났고 각 각의 차이 비교에는 유의성이 없었다. 둘째, 지적장애아동과 지체장애아동 양육자의 우울증 세부항목에서는 의욕상실 부분에서만 유의성이 있었다. 셋째, 지적장애아동 양육자의 우울증 세부항목간의 비교에서는 유의 성이 있었다. 넷째, 지체장애아동 양육자의 우울증 세부항목간의 비교에서는 유의성이 있었다. 다섯째, 지적 장애아동 양육자의 우울증과 세부항목의 상관관계에서는 의욕상실에서 유의한 상관성이 있었다. 여섯째, 지 체장애아동 양육자의 우울증과 세부항목의 상관관계에서는 의욕상실에서 유의한 상관성이 있었다. 본 연구 에서는 두 장애아동의 양육자간 차이는 없었으며 우울증은 장애유형에 상관없이 모두 나타났다. 그리고 세 부항목과 우울증의 상관성에서는 의욕상실에서 유의한 상관성을 보였다. 이것은 장애아동의 양육에서 치료 의 지연으로 인한 의욕상실에서 우울증이 많이 유발됨을 알 수 있다.
Fad or future? Automated analysis of financial text and its implications for corporate reporting

This paper describes the current state of natural language processing (NLP) as it applies to corporate reporting. We document dramatic increases in the quantity of verbal content that is an integral part of company reporting packages, as well as the evolution of text analytic approaches being employed to analyse this content. We provide intuitive descriptions of the leading analytic approaches applied in the academic accounting and finance literatures. This discussion includes key word searches and counts, attribute dictionaries, naïve Bayesian classification, cosine similarity, and latent Dirichlet allocation. We also discuss how increasing interest in NLP processing of the corporate reporting package could and should influence financial reporting regulation and note that textual analysis is currently more of an afterthought, if it is even considered. Opportunities for improving the usefulness of NLP processing are discussed, as well as possible impediments.
Ideological composition of the classroom: testing the effects of polarization on perceptions of open classroom climate among students in five countries

Abstract This quantitative study tests the relationship between ideological classroom composition and perceptions of open classroom climate. Using data from the 2016 International Education Association’s International Civic and Citizenship Study, the study uses latent class analysis and multilevel regression modelling across five countries. First, latent class analysis identified students as low or high socioeconomic status. To assess ideological polarization, the gap between support for gender equality and ethnic rights was calculated between groups. Finally, a multilevel regression model measured the relationship between ideological polarization and students’ perception of open classroom climate. Across three countries, results found negative associations between increased polarization and perception of an open classroom climate. Additional testing identified that polarization modified the relationship between student socioeconomic status and perceptions of open classroom climate in Croatia.
Echinococcus granulosus: The establishment of the metacestode in the liver is associated with control of the CD4+ T-cell-mediated immune response in patients with cystic echinococcosis and a mouse model

The larval stage of the tapeworm Echinococcus granulosus sensu lato (E. granulosus s.l.) caused a chronic infection, known as cystic echinococcosis (CE), which is a worldwide public health problem. The human secondary CE is caused by the dissemination of protoscoleces (PSCs) when fertile cysts are accidentally ruptured, followed by development of PSCs into new metacestodes. The local immune mechanisms responsible for the establishment and established phases after infection with E. granulosus s.l. are not clear. Here, we showed that T cells were involved in the formation of the immune environment in the liver in CE patients and Echinococcus granulosus sensu strict (E. granulosus s.s.)-infected mice, with CD4+ T cells being the dominant immune cells; this process was closely associated with cyst viability and establishment. Local T2-type responses in the liver were permissive for early infection establishment by E. granulosus s.s. between 4 and 6 weeks in the experimental model. CD4+ T-cell deficiency promoted PSC development into cysts in the liver in E. granulosus s.s. -infected mice. In addition, CD4+ T-cell-mediated cellular immune responses and IL-10-producing CD8+ T cells play a critical role in the establishment phase of secondary E. granulosus s.s. PSC infection. These data contribute to the understanding of local immune responses to CE and the design of new therapies by restoring effective immune responses and blocking evasion mechanisms during the establishment phase of infection.
An Assessment of the Challenges affecting Smallholder Farmers in Adopting Biogas Technology in Zambia

The objective of this study was to assess the challenges of adopting biogas technology among rural households in Zambia. Three hundred and twenty households with and without biodigesters were selected randomly from five provinces in the country for the study. A household survey and qualitative methods such as focus group discussions and key interviews were used to collect information. The results show that firewood and charcoal are the main sources of cooking energy in the study areas despite the enormous potential for the utilization of biogas. The use of biogas technology is in its infancy and few households have adopted the technology. The study found that several challenges or factors were responsible for the low adoption status of biogas technology in the study areas. The main challenges were the high cost of installation of biodigesters; lack or limited access to credit to help meet the costs of construction of biodigesters; inadequate numbers of skilled biodigester technicians; and lack of awareness or limited information on biogas technology. Increasing access to affordable credit, as well as awareness raising on biogas technology among rural households are suggested as some of the ways that will assist to promote the adoption of biogas technology as a sustainable renewable energy source for rural populations in Zambia.
AN EXPERIMENTAL STUDY OF AN EDUCATIONAL INTERVENTION TO CHANGE GOAL ORIENTATION

This study examined the effects of intervention with a 2 × 2 factor manipulation, identifying the effects of evaluation indicators (presentation/construction) and evaluator (self/peer) on students’ goal orientation. Specifically, we created five groups (one control group and four experimental groups) and conducted experimental lessons. The learning topic was debate training. The participants were 67 first-year students. Analyses focusing on the cross-lagged relationships of goal orientation before and after the intervention were performed. The effects of the intervention on goal orientation may depend on the individual student’s initial goal orientation. By increasing the level of the intervention, students’ initial goal orientation might have a greater effect on the goal orientation that the student exhibited after the intervention. The results of this study give guidelines on the learning intervention according to student's initial goal orientation.
Whose Child is dying? Household characteristics and under-five mortality in Nigeria

Background. Over 2 000 under-5-year-olds die daily in Nigeria from vaccine-preventable diseases, placing the country as the third largest contributor to the global under-5 mortality rate. Nigeria is at serious risk of not meeting the Millennium Development Goal (MDG) of reducing child mortality by two-thirds (i.e. from an under-5 mortality rate of 93/1 000 in 1990 to 31/1 000 in 2015). Objective. To examine the association between household-level variables and under-5 mortality in Nigeria. Methods. Data were drawn from the 2008 Nigeria Demographic and Health Survey, which elicited information on demographic and health indicators at the national and state levels. A nationally representative sample of 36 800 households was selected. Data were collected from 33 385 women of reproductive age (15 - 49 years) and who had given birth to at least one live infant in the 5 years preceding the survey. Data were analysed using a multilevel-model approach. Results. In total, there were 104 808 live births; 18 121 (17.29%) children died as under-5s and 86 687 (82.71%) survived. Poverty, number of children ever born in a household, number of under-5s in the household, place and region of residence, maternal and paternal age, and maternal and paternal education level were critical determinants of under-5 mortality. Conclusion. The rate of under-5 mortality remains high in Nigeria. This will not be resolved until household-focused interventions are implemented using a tailored framework, and the need to improve maternal education in the country is addressed.
Website Atmosphere, Perceived Flow and Its Impact on Purchase Intention

The online retail industry in Indonesia is growing rapidly and creating increasingly fierce competition. In online retailing, the website is the main media that should always be considered. Website must be developed in such a way as to create attraction, convenience and easiness for consumers, so as to generate purchase intention. One aspect that is still rarely studied in website development is about the websites atmosphere and how it relates to consumer behavior. This study aims to examine the effect of the websites atmosphere on consumers perceived flow and its impact on purchase intention. The method used in this research is quantitative method by applying Multiple Regression Analysis technique. Data were obtained through the distribution of questionnaires to 400 respondents who had visited the online retail website. The results showed that the dimensions of the website atmosphere consisting of virtual layout and design, virtual atmospherics, virtual theatrics and virtual social presence, had a significant effect on perceived flow. Perceived flow in turn also affects purchase intention significantly. Keywords—marketing management; website atmosphere; perceived flow; purchase intention
Digital Cultures: Understanding New Media

Everything you need to know about new media in one accessible, easy to navigate volume! From Facebook to the iPhone, from YouTube to Wikipedia, from Grand Theft Send email us we'll remove relevant links to know about new media for newcomers. Technological change continuing to find more, info facebook. From grand theft auto to navigate, volume is an exploration. Digital democracy mobile phones the newly, emerging themes in ways authentic! From grand theft auto to wikipedia from youtube delete copyright disclaimer this emerging.
Evaluating the Accuracy Rates of Clinical and Radiographic Diagnoses Compared with Histopathologic Diagnosis of Oral Exophytic Lesions

Introduction: The aim of this study was to identify the reasons for failure in clinical, radiographic, and histopathologic diagnoses as well as their interactions with each other. Methods: Personal information and lesion characteristics of 51 patients with central or peripheral exophytic lesions were collected in Mashhad dental school. Specialists determined clinical and radiographic diagnoses and after taking biopsy, the clinical and radiographic diagnoses were compared with histopathologic diagnosis. Results: Fifty three patients with oral exophytic lesions were evaluated among which 66.6% were peripheral and 33.4% were central exophytic lesions. Males constituted 52.9% of the patients while 47.1% were female. The first clinical and radiographic diagnoses were not confirmed with the histopathologic diagnosis in some patients. 80.4% of the first clinical diagnoses were consistent with the pathologic reports and in other cases, the clinical diagnosis were not confirmed histopathologically. In addition, radiographic diagnoses in six patients were not consistent with pathologic diagnosis. Conclusion: Great concordance was observed between clinical and radiographic diagnosis with pathologic reports.
Pattern of acne vulgaris in women, attending in a tertiary care hospital.

A cross-sectional study was carried out for a period of one year in the outpatient department of Dermatology and Venereology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. Seventy female patients having acne vulgaris were selected. The study showed that the mean age of the cases was 22.43 with standard deviation 5.2 years and highest percentage of patients were in the age group 20-24 years (41.4%), highest percentage of patients was unmarried among the cases (74.3%) and proportion of secondary (35.7%) and higher secondary education (20%) were found to be high among the cases. The study showed that proportion of student (65.7%) and housewife (17.1%) were found to be high among the cases. The mean duration of disease was 62.6 months and all the patients had presented with comedones (blackheads and whiteheads). All the patients had acne in the face and it was found that 60% had moderate type acne. Considering the pattern of treatment received, 42.9% of the patients mentioned that they used topical ointment, 37.1% had received herbal medication and 25.7% had received systemic medication. To get an overall impression of the country regarding acne vulgaris, more integrated study is needed. This was a study on a limited number of cases. Future studies must include economical support, then large sample size could be ensured and study finding would be more reliable. There is a great need of epidemiological studies also, with sufficient follow-up, systematic reviews and meta-analyses on this issue. DOI: http://dx.doi. org/10.3329/jdnmch.v18i1. 12234 J. Dhaka National Med. Coll. Hos. 2012; 18 (01): 18-23
Composición y estructura de redes personales en entornosde aprendizaje personales

Para citar: Casquero, O. (2013). Composicion y estructura de redes personales en entornos de aprendizaje personales. En L. Castaneda y J. Adell (Eds.), Entornos Personales de Aprendizaje: Claves para el ecosistema educativo en red (pp. 151-160). Alcoy: Marfil.
Low Rates of Controller Medication Initiation and Outpatient Follow-up After Emergency Department Visits for Asthma

AL Andrew, RJ Teufel, WT. Basco. J Pediatr. 2012;160(2):325–330 To determine what proportion of patients who are seen in the emergency department (ED) for asthma receive inhaled corticosteroids (ICSs) or attend follow-up appointments. The sample included a total of 3435 patients in the South Carolina Medicaid database between 2007–2009 aged 2 to 18 years with an ED visit for asthma. Patients who were in the top 99th percentile for total number of ED visits, had been admitted for asthma, or had an ICS claim in the 2 months preceding the ED visit were excluded. The study was a retrospective cohort analysis. The diagnosis of asthma was identified by …
Evidence-Based Practice in “the Real World”

The term evidence-based practice (EBP) has developed into a mantra not just within the medical area of treatment, but within the psychosocial realm of treatment as well. Today, decision-makers and funding authorities are increasingly demanding that psychosocial treatment should be evidence-based and that the different types of treatment facilities should attempt to adapt to this, inter alia by providing offers that are reputed to be evidence-based. In this article, EBP is viewed under a slightly different perspective than the one usually used when discussing it. It is claimed that evidence-based counselling and therapeutic methods only account for a small part of the strategies that are relevant for treating clients with substance and/or alcohol misuse. In the first part of the article, EBP is defined and placed in relation to evidence-based counselling/therapy (EBC/T). In the article's second part, the relevance of – not least – EBC/T in the “real world” is discussed. The real world is defined as, among other things, “what clients receive, not what they are offered” and “what clients need, not what the system needs”. This is illustrated by discussing two Danish research projects that demonstrate, inter alia, that what is received does not have much in common with what is offered.
Incidence and predictors of adverse drug reactions caused by drug-drug interactions in psychiatric patients: An empirical study

Introduction: Potential drug-drug interactions (pDDIs) are very frequent in psychiatric practice and result in poor tolerability or reduced efficacy, or both, which can negatively impact patient outcomes. Clinically significant drug-drug interactions (DDIs) are the ones that can result in changes in the therapeutic effect of one of the two drugs, that is, adverse drug reactions (ADRs). The aim of this study was to identify the incidence and pattern of ADRs occurring as results of DDIs in patients with mental illness. Materials and Methods: This empirical study reviewed all the patients with a psychiatric diagnosis as per the Tenth Revision of the International Classification of Diseases (ICD-10) and received at least two medications. DDIs were identified using drug interaction software/databases, standard textbooks, and references. Result: A total of 122 ADRs were identified from 97 patients. The majority [n = 98 (68.5%)] of the DDIs involved pharmacodynamic interactions. Risperidone (41 occurrences) exhibited the greatest propensity to interact with other medications, and the most commonly observed ADR was extrapyramidal symptoms (EPS) (n = 33). More than half of the ADRs were “possible” in their causal relationship. Conclusion: The incidence of ADRs caused by DDIs in this study was 12%. Pharmacodynamic interactions accounted for the majority (68.5%) of ADRs. ADRs are an important cause of the increased burden of disease and unnecessary health-care expenditure. Intense monitoring of psychiatric patients for any DDI, and early detection and prevention of the same may result in improved therapeutic outcomes and decreased unnecessary health-care expenditure.
REDUCING UNEMPLOYMENT MALAISE IN NIGERIA: THE ROLE OF ELECTRICITY CONSUMPTION AND HUMAN CAPITAL DEVELOPMENT

One of the greatest challenges that Nigeria is confronted with and which on the average has continued to witness a rising trend over the years is unemployment. Its scourge is known to be responsible for a high level of poverty, inequality, increasing rate of criminality and general low level of living in the country. This study examined how electricity consumption and human capital can be used to reduce unemployment in Nigeria. The study obtained secondary data and analysed the data with the Johansen co-integration technique. The study found out that electricity consumption negatively impact unemployment, so also is government education expenditure. The result showed that a 1% increase in electric power consumption will lead to about 0.22% decline in the level of unemployment and 1% increase in education expenditure will bring about 0.17% decrease in the rate of unemployment. Therefore, the study recommends that the government should put in place policies and measures that will enhance the turn-out of quality graduates with skills and competence to chant the course of development by all stakeholders in the education sector.
A conjecture on global optimization using gradient-free stochastic approximation

A concern with iterative optimization techniques is that the algorithm reaches the global optimum rather than gets stranded at a local optimum value. One method used to try to assure global convergence is the injection of extra noise terms into the recursion, which may allow the algorithm to escape local optimum points. The amplitude of the injected noise is decreased over time (a process called "annealing"), so that the algorithm can finally converge when it reaches the global optimum point. In this context, we examine the performance of a certain "gradient free" stochastic approximation algorithm. We argue that, in some cases, the naturally occurring error in the gradient approximation effectively introduces injected noise that promotes convergence of the algorithm to a global optimum. The discussion is supported by a numerical study.
The Application of Fama-French Capital Asset Pricing Model and Quantile Regression on Chinese Stock Market

Fama-French three factors asset pricing model has been well documented for the stock market cross the world. This research will apply Fama-French model to Chinese stock market using the quantile regression approach. All the portfolios are sorted by size and book-to-market ratio to mimic the market size factor and market value factor. The regression reveal that portfolios returns are positively related with market risk and investors will make more profit by holding stocks with smaller company size and higher book-to-market ratio. With the assumption that the returns are normally distributed and expected returns are linearly dependent on three factors, existing studies on Chinese stock market have used ordinary least square (OLS) method to test asset pricing models. These assumptions are not valid in most of the markets. Thus, the present study tests the three risk factors model using quantile regression with the same data set. The results of the study reveal that the when it comes to extreme values in a distribution, the OLS method becomes inefficient. Quantile regression is a better way for investors to examine the extreme values in the distribution tails. JEL classification: C31; G12; G51