Miracle-dz/UniFAR-FTUs huggingface dataset:
Analisis Faktor-Faktor Yang Mempengaruhi Pemeriksaan Deteksi Dini Kanker Leher Rahim Di Puskesmas Panjang Dan Puskesmas Sukaraja Kota Bandar Lampung

Kanker leher rahim merupakan penyakit penyebab kematian terbesar ke-8 didunia, di Indonesia diantara penyakit kanker, penyakit kanker leher rahim penyumbang kematian ke dua. Kasus kematian ini semakin tinggi karena pasien datang kepelayanan kesehatan pada stadium lanjut, sehingga perlu pemeriksaan dini pada orang yang beresiko. Sejak tahun 2007 Kemenkes RI telah mengembangkan program deteksi dini kanker leher rahim. Data Dinas Kesehatan Kota Bandar Lampung 2015, pencapaian target deteksi dini kanker leher rahim puskesmas Panjang 0,14% dan puskesmas Sukaraja 0,20%. Hasil ini masih belum mencapai target 10%. Tujuan Penelitian ini adalah menganalisis faktor-faktor yang mempengaruhi pemeriksaan deteksi dini kanker leher rahim di puskesmas Panjang dan pukesmas Sukaraja Kota Bandar Lampung tahun 2017. Jenis penelitian ini survai analitik dengan pendekatan kuantitatif, berdesain Cross Sectional. Populasi adalah semua pasien wanita berumur 20 tahun lebih yang datang ke Puskesmas Panjang dan Puskesmas Sukaraja, sebanyak 2.801orang. Tehnik pengambilan sampel menggunakan tabel penentuan, dengan jumlah sampel 111 orang. Alat pengumpulan data menggunakan kuesioner dengan tehnik wawancara. Analisis univariat dengan persentase, bivariat dengan chi square, dan multivariat dengan regresi logistik. Hasil penelitian ini menunjukan ada pengaruh faktor predisposisi yaitu pendidikan OR 4,626 dan pengetahuan OR 0,217. Yang artinya responden yang berpendidikan tinggi dan pengetahuan baik peluangnya lebih besar melakukan pemeriksaan deteksi dini kanker leher rahim dibanding dengan pendidikan rendah dan pengetahuan kurang. Saran bagi Dinas Kesehatan Kota Bandar Lampung, bekerjabersama dengan pemerintah kota dan propinsi. Peningkatan kualiastas, kuantitas nakes tentang deteksi dini kanker leher rahim sehingga banyak nakes yang memberikan penyuluhan di masyarakat. Bagi Puskesmas melakukan peningkatan kegiatan penyuluhan, tentang deteksi dini kanker leher rahim dengan menggunakan berbagai media di kegiatan pelayanan atau kegiatan yang ada di masyarakat.
Unmasking the Masquerader: A Delayed Diagnosis of MS and Its 4.5 Years of Implications in an Older African American Male

Multiple sclerosis (MS) has classically been described as a disease of the young Caucasian female. While the prevalence may seem to be higher in Caucasians (CAs), recent studies suggest that the real incidence of MS may actually be higher in African Americans (AAs). Here, we discuss a nonclassical case of MS in an older African American male, prognostic factors, disease patterns in African Americans, and how a delay in diagnosis and socioeconomic factors can lead to worse outcomes. In patients that present with possible symptoms of MS, a high suspicion for MS should be entertained even in epidemiologically atypical patients to prevent delay in diagnosis and irreversible disability.
Awareness, attitude, participation and use of technology in birth preparedness and complication readiness among husbands of women availing obstetric care at a rural maternity hospital in South Karnataka

Background: Birth preparedness and complication readiness (BPCR) is an evidence-based strategy to reduce maternal mortality. Husbands have an important role to play in birth preparedness. There is paucity of data regarding husband’s participation and the use of technology in BPCR. The objective is to assess awareness, attitudes and the use of mass media and technology in BPCR among husbands of women availing obstetric care at a rural maternity hospital.Methods: A cross-sectional study was conducted in a rural maternity hospital in Ramanagara district, Karnataka. Husbands of women of more than 28 weeks of gestation, or postnatal mothers up to 6 weeks after delivery were included in the study.Results: Of the 133 participants, only 37.6% of the husbands had adequate awareness of BPCR, 62.4% had adequate participation in BPCR. Husbands’ participation was highest in saving money for delivery (75.9%), and lowest for arranging a blood donor (27.8%). Commonest source of information regarding BPCR was mobile phone (30.8%). Husbands awareness of BPCR was associate with reading MCP card OR=5.36 (2.47-11.63), seeing BPCR- related posters in hospital OR=6.59 (1.32-33.13) and using mobile phone for accessing BPCR-related information OR=2.28 (1.07-4.85). Husbands participation in BPCR was associated with awareness of BPCR OR=3.72 (1.65-8.41) and accompanying wife for antenatal visits OR=2.84 (2.25-3.59). Only one third of husbands felt it necessary to accompany their wife for antenatal visits or delivery.Conclusions: The MCP card and mobile phone technology may be further tapped to improve husband’s awareness and participation in BPCR, besides encouraging men to accompany their wife for antenatal visits.
Study the Expression of CD10 in Prostate Carcinoma and its Correlation with Various Clinicopathological Parameters

Background and Objective: Adenocarcinoma of the prostate is the second most common cause of cancer. The loss of CD10 is a common early event in human prostate cancer and is seen in lower Gleason Score malignancies while increased and altered expression is seen in high Gleason Score tumors, lymph nodes and bone metastasis. Material and Methods: This was a prospective observational study conducted on 75 patients suspected to have prostate cancer. Immunohistochemical profile was assessed for PSA, AMACR and CD10 immunostaining. The intensity of CD10 expression and pattern of CD10 staining of tumor cells was evaluated. Results: The patients were in age group of 50-90 years with a mean age of 70.97 ± 9.51 years. As the Grade Group/Gleason Score increased, the number of cases showing negative expression decreased and the pattern of expression changed from membranous to cytoplasmic to both types of expression. As the serum PSA levels increased the intensity of expression changed from focally positive to diffusely positive. The pattern of expression also changed from membranous to cytoplasmic to both (membranous + cytoplasmic) types of expression with an increase in PSA levels. Conclusion: By immunohistochemical analysis we can identify CD10 positive tumors, which may warrant more aggressive initial therapy. A number of drugs against CD10 are available based on which potential targeted therapies could be formulated.
A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab

Secukinumab is an IgG monoclonal antibody widely used for treatment of ankylosing spondylitis, psoriasis, and psoriatic arthritis. Recently, there has been increasing controversy regarding potential adverse effects of the drug especially in those with underlying inflammatory bowel disease. We present the case of a young male patient who developed severe new-onset ulcerative colitis following initiation of secukinumab for psoriasis, with excellent response and rapid resolution of symptoms with infliximab.
Spinal Cord Reperfusion Injury: Case Report, Review of the Literature, and Future Treatment Strategies

A rare complication of cervical spine decompression is acute paralysis following the procedure. This neurologic deficit is thought to be due to reperfusion injury of a chronically ischemic spinal cord and is referred to as "white cord syndrome" given the pathognomonic finding of hyperintensity on T2-weighted MRI. Three prior cases have been reported. We present a case of transient quadriplegia following posterior cervical decompression. A 41-year-old male with cervical spondylotic myelopathy presented with bilateral progressive upper extremity weakness, hyperreflexia, and cervical spine MRI showing severe cord compression at C1 and partial hyperintense signal. Intraoperatively, after C1 bony decompression and without perceptible technical cause, the patient experienced a complete loss of both somatosensory evoked potentials (SSEPs) and motor evoked potentials (MEPs) with an eventual return to baseline prior to completing the operation. The patient awoke from surgery with acute quadriplegia without perceptible technical cause (intraoperative compression or evident anatomic compromise). An immediate postoperative MRI revealed a more pronounced hyperintensity in the central cervical cord on T2-weighted sequences. Treatment with increased mean arterial pressure (MAP) therapy and dexamethasone resulted in the patient regaining some movement over a period of hours and full strength over a period of months. The mechanism of acute weakness following cervical spine decompression in the absence of perceptible technical cause is not fully understood, but current theory suggests that a reperfusion injury is most likely the cause. It remains a diagnosis of exclusion. Familiarity with this potential postoperative complication can aid in appropriate postoperative therapy with early diagnosis and intervention leading to restored spinal cord function and excellent prognosis.
Rapid Intrahepatic Progression of Hepatocellular Carcinoma after Transarterial Chemoembolization: A Case Report

The prevalence of hepatocellular carcinoma (HCC) is increasing worldwide. Multiple strategies are available for its management including surgical removal, chemotherapeutic drugs, and ablative and chemoembolization procedures. Transarterial chemoembolization (TACE) is currently being used for the unresectable intrahepatic tumor with no vascular invasion or metastasis to other organs. The common adverse effects associated with this technique involve self-limiting fever, vomiting, and abdominal pain. Liver failure is reported in a few cases. In this report, we present a case of 37-year-old HCC patient who experienced rapid progression of tumor following TACE. Our patient came to the Gastroenterology & Hepatology Department, Nishtar Hospital, Multan, with signs concerning acute liver failure within a few months following TACE. On triphasic computed tomography (CT) scan, there was evidence of multiple new infiltrating lesions in both lobes of the liver and portal vein thrombosis, which were not present before TACE procedure. Hence, we made a diagnosis of acute, chronic liver disease due to the rapid intrahepatic progression of HCC. This is a rare side effect of TACE procedure and highlights the significance of proper counseling of the patients undergoing this intervention.
Asthma and Chronic Obstructive Pulmonary Disease Associated With Occupational Exposure in Dairy Farmers - Importance of Job Exposure Matrices

AIM: To evaluate the prevalence of chronic respiratory symptoms, lung function impairment, and chronic obstructive respiratory diseases in dairy farmers. Our objective is to then examine their relation to exposure duration and to explore the usefulness of job exposure matrices as tools for exposure assessment, and predictors for respiratory health impairment. METHODS: A cross-sectional study was performed, including 83 dairy farmers (mean age: 52.6 ± 8.7 years; mean exposure duration: 23.7 ± 7.6 years) and 80 office workers as a control group (mean age: 52.7 ± 8.2 years) matched for age, smoking habits, and socioeconomic status. Methods of evaluating examined subjects included a questionnaire on respiratory symptoms in the last 12 months, spirometry and histamine challenge, as well as the use of job exposure matrices (JEM). RESULTS: Dairy farmers had a significantly higher prevalence of cough (38.5), phlegm (27.7%), and wheezing (21.7%), than controls (p < 0.05). All mean baseline spirometric parameters were lower in dairy farmers compared to the controls, but statistical significance was confirmed only for MEF25, MEF50, and MEF75% (p = 0.010, p = 0.001, and p = 0.004, respectively). The prevalence of bronchial hyperresponsiveness, asthma, and chronic obstructive pulmonary disease was higher in dairy farmers but without statistical significance. JEM were useful tools for exposure assessment and predictors of factors for asthma and COPD development. CONCLUSION: The results suggest that occupational exposure among crop farmers is associated with a higher prevalence of respiratory symptoms, lung function impairment, and a higher prevalence of chronic respiratory diseases. JEM showed good potential for farming exposure evaluation and promoted their applicability within the diagnostic algorithm focused on respiratory health assessment.
Real-time High Quality HDR Illumination and Tonemapped Rendering

Real-time realistic rendering of a computer generated scene is one of the core research areas in computer graphics as it is required in several applications such as computer games, training simulators, medical and architectural packages and many other fields. The key factor of realism in the rendered images is the simulation of light transport based on the given lighting conditions. More natural results are achieved using luminance values near to the physical ones. However, the vast range of real luminances has a far greater range of values than what can be displayed on standard monitors. As a final step to the rendering process, a tonemapping operator needs to be applied in order to transform the values in the rendered image to displayable ones. Illumination of a scene is usually approximated with the rendering equation which solution is a computational expensive process. Moreover, the computational cost increases even more with the increase in the number of light sources and the number of vertices of the objects in the scene. Furthermore, in order to achieve high frame rates, current illumination algorithms compromise the quality with assumptions for several factors or assume static scenes so that they can exploit precomputations. In this thesis we propose a real-time illumination algorithm for dynamic scenes which provides high quality results and has only moderate memory requirements. The proposed algorithm is Despina Michael––University of Cyprus, 2010 based on factorization of a new notion that we introduce: fullsphere irradiance, which allows the pre-integration of contribution of all light sources within the same value for any possible receiver. Recent illumination algorithms, including ours, usually use environment maps to represent the incident lighting in the scene. Environment maps enable natural environment lighting conditions to be used by using high dynamic range (HDR) values. Typically the HDR obtained result of the illumination needs to be tonemapped into LDR values that can be displayed on standard monitors. Traditionally tonemapped techniques give emphasis either to frame rate (global operators) or to the quality (local operators) of the resulting image. In this thesis, we propose a new framework: selective tonemapping which addresses both requirements. The key idea of this framework is to apply the expensive computations of tonemapping only to the areas of images which are regarded as important. A full rendering system has been developed which integrates HDR illumination computation and the selective tonemapping framework. Results show high quality images at real-time frame …
Chronotype-Dependent Changes in Sleep Habits Associated with Dim Light Melatonin Onset in the Antarctic Summer

Dim light melatonin onset (DLMO) is the most reliable measure of human central circadian timing. Its modulation by light exposure and chronotype has been scarcely approached. We evaluated the impact of light changes on the interaction between melatonin, sleep, and chronotype in university students (n = 12) between the Antarctic summer (10 days) and the autumn equinox in Montevideo, Uruguay (10 days). Circadian preferences were tested by validated questionnaires. A Morningness–Eveningness Questionnaire average value (47 ± 8.01) was used to separate late and early participants. Daylight exposure (measured by actimetry) was significantly higher in Antarctica versus Montevideo in both sensitive time windows (the morning phase-advancing and the evening phase-delaying). Melatonin was measured in hourly saliva samples (18–24 h) collected in dim light conditions (<30 lx) during the last night of each study period. Early and late participants were exposed to similar amounts of light in both sites and time windows, but only early participants were significantly more exposed during the late evening in Antarctica. Late participants advanced their DLMO with no changes in sleep onset time in Antarctica, while early participants delayed their DLMO and sleep onset time. This different susceptibility to respond to light may be explained by a subtle difference in evening light exposure between chronotypes.
The effect of maternal body mass index on clinical and ultrasonic estimations of fetal weight

Background assessment of fetal weight (clinically or by ultra sound) has an important issue to decrease maternal and fetal comp lications during labour. Objective: To assess the effect of maternal body mass index on clinical and sonographical estimation of fetal weight. Patients and methods: (80) Eighty pregnant women were studied from the start of Octob er 2007 to the end of September 2008 in Al-Kadhymia teaching hospital. These women had single, cephalic and term pregnancy. About 24 hour prior to delivery of the f etus, clinical estimation of fetal weight using Leopold's maneuver was done followed b y sonographic estimation of fetal weight using Hadlock's equation. Then a compa rison of clinical and sonographical estimation of fetal weight with the w ight of the newborn baby was done. The accuracy of fetal weight estimation was d one in obese and non obese women. Results: Clinical estimation of fetal weight has a better ag eement with true birth weight than sonographic estimation in low and high BMI pregnant women. Both clinical and sonographic estimation of fetal weight under-estimate true birth weight in women with low and high BMI. , the agreement betwee n clinical estimation of fetal weight and birth weight was higher than sonographic al estimation, both in high and low BMI groups. Sonographical estimation of fetal w eight tended to under estimate the true fetal weight in both low and high BMI grou ps. Clinical estimation of fetal weight tended to under estimate true fetal weight i n both low and high BMI groups, but had a better correlation with true fetal weight than sonographical estimations. Conclusion: The accuracy of clinical estimation of fetal weight was better than sonographical estimation and was not influenced significantly by maternal BMI.
An observational study assessing the pathways to care among treatment seeking users of natural opiates

Abstract Background: Natural opiate users constitute a large proportion of opioid dependent individuals in India, and enjoy socio-cultural sanction in certain parts of the country. However, no study has assessed the pathways to care among this population in India. Objective: To assess the pathways to care among treatment-seeking natural opiate dependent individuals. Method: This cross sectional, explorative study was conducted at a tertiary care drug treatment centre located in North India. A total of 125 male participants aged >18 years, seeking treatment for natural opiate dependence from our outpatient clinic were included. A semi-structured proforma and WHO mental health encounter form was applied to assess socio-demographic, treatment details and pathways to care. Results: The mean age was 46.17 (±11.98) years. Poppy husk (phukki/doda/posht) was the most common primary natural opiate used (84%). First point of treatment contact was addiction psychiatrist (n = 90; 72%) in majority. First time treatment seeking was either by self-referral (60.8%) or referral by relatives and friends (24.8%) with mean time lag of 18.63 years after the onset. Conclusion: Natural opiates dependent patients seek treatment late in the course of their illness, often directly from a tertiary addiction treatment centre. Barriers to seek treatment needs to be addressed.
Possible role of gingival crevicular fluid levels of Chemerin and Fibroblast growth factor 21 as biomarkers of periodontal disease in diabetic and non-diabetic patients. A diagnostic accuracy study

Background: The relation between diabetes mellitus and periodontitis has been discussed for years. Many adipokines were reported to play a major role in periodontal inflammation. Chemerin is one of these adipokines which is blamed to be involved in inflammatory conditions such as diabetes. Fibroblast growth factor 21 (FGF21) is another adipokine which is believed to induce regulation of glucose. The current study aimed to spot the light on the potential role of gingival crevicular fluid (GCF) level of FGF21 and chemerin as biomarkers of periodontal disease activity and an attempt to understand their role in the link between periodontitis and diabetes. Methods: The study was conducted on 45 individuals, 15 diabetic patients with periodontitis, 15 periodontitis patients and 15 healthy controls. GCF samples were collected from all participants for assessment of chemerin and FGF 21. Samples were analysed using enzyme linked immunosorbent assay (ELISA). Results: Periodontitis patients with diabetes had significant higher levels of chemerin and FGF21 than the periodontitis patients without diabetes followed by healthy controls. ROC analysis showed a 100% diagnostic accuracy for chemerin and FGF21. Conclusion: FGF21 and chemerin in GCF are valuable biomarkers of periodontal disease suggesting a role in the link between diabetes and periodontitis.
The relationship between body mass index and preeclampsia: A systematic review and meta-analysis

Abstract Background One of the causes of maternal and fetal mortality and morbidity is pregnancy-induced hypertension, the most common form of which is preeclampsia that causes many complications for mother and fetus. Objective The aim of this systematic review and meta-analysis was to determine the relationship between body mass index (BMI) and preeclampsia in Iran. Materials and Methods Using valid keywords in the SID database, PubMed, Scopus, data obtained from all the articles, which were reviewed in Iran between 2000 and 2016, were combined using the meta-analysis method (random-effects model) and analyzed using STATA version 11.1. Results A total number of 5,946 samples were enrolled in 16 studies with the mean BMI values of 25.13, 27.42, and 26.33 kg /m2 in the healthy, mild, and severe preeclamptic groups, respectively. Conclusion The results of this study revealed that there is a significant relationship between BMI and the risk of preeclampsia, so it can be said that BMI may be one of the ways to diagnose preeclampsia.