Miracle-dz/UniFAR-FTUs huggingface dataset:
Work-related chronic venous disease in office and bakery workers

A prospective study was undertaken in order to establish the prevalence and risk factors of chronic venous disease (CVD) in two occupational groups: office employees working in a prolonged sitting or standing position, and people working in bakeries, in a hot microclimate. It included 160 individuals over 40 years old, 97 women and 63 men. A survey assessing subjects' work place ergonomics, Doppler sonography - currently the diagnostic tool of choice in the assessment of sufficiency of venous valves, and an observational study were performed. Doppler signs of CVD in persons working in sitting or standing positions and in hot microclimate were found in 59.4%, 83.4% and in 76.4%, respectively. Most often diagnosed were perforating veins and vena saphena magna incompetence. Occurrence of CVD was significantly higher in people working in a standing position than in those working in a sitting position (p-value = 0.0145). Occurrence of CVD among office workers working in sitting or static standing conditions and among people working in a hot microclimate were comparable (p-values = 0.1152 and 0.7116, respectively). Conclusions: Occupational CVD is a frequent condition among office workers and people working in a hot microclimate. Static standing position at work constitutes a significantly greater risk for CVD development than prolonged sitting or work in a hot microclimate and thus should be a subject for specific prophylaxis interventions.
Guidelines for Clinical Practice: From Development to Use

Guidelines for the clinical practice of medicine have been proposed as the solution to the whole range of current health care problems. This new book presents the first balanced and highly practical view of guidelines--their strengths, their limitations, and how they can be used most effectively to benefit health care. The volume offers * Recommendations and a proposed framework for strengthening development and use of guidelines. * Numerous examples of guidelines. * A ready-to-use instrument for assessing the soundness of guidelines. * Six case studies exploring issues involved when practitioners use guidelines on a daily basis. With a real-world outlook, the volume reviews efforts by agencies and organizations to disseminate guidelines and examines how well guidelines are functioning--exploring issues such as patient information, liability, costs, computerization, and the adaptation of national guidelines to local needs.
Epilepsy and glucose transporter 1 deficiency syndrome

Abstract Glucose transporter 1 deficiency syndrome (GLUT-1 DS) is a unique genetic syndrome representing a severe metabolic encephalopathy, as a result, of insufficient glucose transport into the brain. Infantile onset seizures, acquired microcephaly, spasticity, ataxia, dystonia and mental retardation are the cardinal features of the syndrome. Over the years, the clinical spectrum of GLUT-1 DS has been expanded beyond the original phenotype. Clinical features of seizures present with a wide spectrum, however generalized seizures are reported as the most common seizure types in the patients received diagnosis of GLUT-1 DS. In recent years, there are number of epilepsy syndromes described in association with GLUT-1 DS has been shown to be the underlying cause for 10% of early onset absence epilepsy, 5% of Myoclonic astatic epilepsy (MAE) and 1% of idiopathic generalized epilepsies. Seizures are often remained refractory despite the treatment with a number of antiepileptic medications. Valproate and benzodiazepines are relatively contraindicated for the treatment of seizures in this syndrome. Ethanol and caffeine also inhibits GLUT-1 transport activity and may exacerbate seizures. Ketogenic diet remains the most effective treatment in order to meet the energy demand of developing brain. GLUT-1 DS should be suspected in the individuals with family history of idiopathic generalized epilepsy and/or paroxysmal dyskinesia. Moreover, the families with absence epilepsy with a wide range of age of onset or seizure types should also be screened for GLUT-1 DS.
A Randomised Trial on the Treatment of Refractory Status Epilepticus

This study failed to show a significant difference in outcome between those receiving propofol versus barbiturates in the treatment of refractory status epilepticus, except in duration of mechanical ventilation. However, due to a failure to recruit sufficient numbers of patients, the trial was significantly underpowered and we recommend caution when drawing any conclusions from the data. Level of evidence: 1− (RCT with a high risk of bias)
Endurance improvement of mini UAVs through energy harvesting from atmospheric gusts

Cette these a pour but de decouvrir la faisabilite et le potentiel de la recuperation d'energie a partir de rafales atmospheriques pour les micro et mini vehicules aeriens sans pilote. L'atmosphere sert de grande source d'energie pouvant etre recoltee afin d'accroitre la performance des petits UAV sous la forme d'une autonomie et d'une autonomie etendues. Il est bien connu que de nombreuses especes d'oiseaux utilisent diverses techniques de vol pour obtenir des performances de vol etonnantes. Compte tenu du fait que les vehicules susmentionnes partagent la taille et la vitesse de vol avec des depliants naturels, cette these peut etre consideree comme une application des techniques de vol bio-inspirees pour les vehicules construits par l’homme. Cette etude de trois ans visait a etablir une derivation theorique des equations qui decrivent la dynamique de vol d'un aeronef en presence d'un environnement en rafales. La premiere realisation a ete la demonstration du mecanisme de recuperation d'energie et des parametres d'influence a travers des simulations decrivant le vol en modele de masse ponctuelle d'aeronef avec un controle optimise de l'ascenseur en presence d'un profil de vent sinusoidal et stochastique. La realisation suivante est liee a un systeme sensoriel inspire par la biologie qui utilise des mesures de pression des ailes pour estimer l’angle d’attaque local. Ce systeme particulier a ete utilise dans l’estimation du champ de vent, en tant que mecanisme decisif et protection contre le decrochage. Enfin, les dernieres contributions sont liees a l’experience et aux resultats obtenus lors d’essais en vol visant a prouver l’augmentation de l’etat energetique de l’avion lors des manœuvres de recuperation d’energie. La premiere campagne d'essais en vol a ete realisee avec un mini-UAV disponible dans le commerce equipe de sondes a trous multiples et d'un controleur concu sur mesure. Cette campagne a demontre l’augmentation de l’etat d’energie dans un fort gradient de vent horizontal. La deuxieme campagne d'essais en vol a ete realisee avec une aile volante equipee d'un systeme de detection de pression pour l'estimation du champ de vent. Cette campagne a egalement implique des economies supplementaires sur la consommation d'energie electrique lors des vols de recuperation d'energie.
"Getting on Top of Pain": a Critical Analysis of Surgical Nurses' Talk About Their Work with Hospitalised Patients Reporting Pain

This thesis investigates the relationship between language, 'discourse' and professional knowledge and power in a specific context; that of surgical nurses' "talk" about their work managing pain in hospitalised patients. This thesis argues that the work of 'caring for' hospitalised surgical patients who report pain is influenced by discourses which are predicated on different readings/understandings of the body/patient, and from which different knowledge is constructed. Of interest to this thesis are the discourses of biomedicine and nursing, and their role in constructing a particular reality/ies which determine the ways in which surgical nurses talk about their work managing pain. Using the method of critical discourse analysis, the "texts" of transcribed audio-taped conversations with four registered nurses working in surgical specialties were analysed to uncover 'discourses of pain management'. The results of the analysis indicate that the biomedical construction of pain, and approaches to pain management, remain the dominant influence over surgical nurses' practice. There was evidence of nursing discourses with an emphasis on nurse-patient relationships also playing a role. These discourses were critically examined for what they reveal about relations of professional knowledge and power in this specific context of the nurses' practice. The implications for nursing and nursing research are considered significant because the study critically (re)presents a different perspective on, and reality for surgical nurses' pain management practices. In so doing, it elucidates an explanation for, and understanding of, why surgical nurses take care of patients reporting pain in particular ways.
Effect of Glibenclamide alone versus Glibenclamide and Honey on Oxidative Stress in Pancreas of Streptozotocin-Induced Diabetic Rats

Summary: Diabetes mellitus is a public health problem with increasing global prevalence. In spite of its management, both microvascular and macrovascular complications partly linked to oxidative stress are not efficiently prevented. This study compared the effect of glibenclamide alone with that of combined glibenclamide and honey on pancreatic oxidative stress in streptozotocin-induced diabetic rats. Diabetes was induced by streptozotocin (60 mg/kg; ip). Rats were randomly divided into four groups and treated as follows: non-diabetic rats received distilled water (0.5ml/day), diabetic rats administered distilled water (0.5ml/day), glibenclamide (600 µg/kg/day) or a combination of glibenclamide (600 µg/kg/day) and honey (1.0 g/kg/day). The animals were treated orally once daily for four weeks. Fasting blood glucose was significantly increased in diabetic rats. The diabetic pancreas showed increased levels of malondialdehyde (MDA), reduced activity of catalase (CAT) and increased activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx). Treatment of diabetic rats with glibenclamide reduced hyperglycemia but produced no significant effects on the MDA levels, activities of SOD, GPx, and CAT. In contrast, the pancreas of diabetic rats that received combination of glibenclamide and honey showed increased CAT activity, reduced MDA levels and GPx activity while blood glucose was also reduced. The results of glibenclamide alone suggest that decreased hyperglycemia does not necessarily translate to reduced oxidative stress. These data demonstrate the beneficial effects of combining honey with glibenclamide on oxidative stress parameters in pancreas of diabetic rats. Industrial relevance: Diabetes mellitus is one of the five leading causes of death globally. The increasing prevalence of this disorder not only poses severe medical implications but also has financial consequences due to the costs of managing this disorder and its associated complications. Considering that diabetes mellitus is a heterogeneous disorder with multiple causes, the combination of therapeutic agents aimed at specific patho-biological pathways of diabetes and its complications may result in a better and more effective management of this disorder. Even though the currently available drugs may be valuable in the management of diabetes mellitus, these drugs have limitations due to undesirable adverse effects such as hypoglycemia, weight gain, secondary failure, and inability to arrest pancreas degeneration or diabetic complications which have been linked to oxidative stress. Since many natural products have reduced toxicity, the hypoglycemic effect of tualang honey coupled with its protective effects on pancreas and kidney against oxidative damage would appear to make it a suitable candidate for such adjunctive use.
The Date and Origin of Black-on-Red Ware: The View from Megiddo

Our study of Black-on-Red sherds found in well-stratified Iron IIA contexts at Megiddo shows that the earliest examples of this ware appear in an early stage of the Late Iron IIA, radiocarbon dated to the late 10th to early ninth century B.C.E. An archaeometric analysis of 10 sherds reveals that they were manufactured in Cyprus, meaning that Black-on-Red vessels were produced on the island as early as ca. 900 B.C.E. This makes Gjerstad's theory regarding the “Levantine Phase” in the production history of this ware obsolete. It is noteworthy that Black-on-Red vessels of Type IV (dated to the eighth and early seventh centuries B.C.E. based on stylistic considerations) are present in secure contexts in levels Q-5 and Q-4 at Megiddo, radiocarbon dated to the late 10th and ninth centuries B.C.E.
Effects of different propofol injection speeds on blood pressure, dose, and time of induction

Blood concentration of propofol depends on many factors, such as age, gender, body weight, dose, infusion rate, and cardiac output. This study primarily investigated the effect of infusion rate on blood pressure changes. Secondarily induction time and induction dose were studied. Materials and methods: Propofol was administered at 200 (P200), 300 (P300), or 400 mL h-1 (P400) until loss of consciousness using bispectral index (BIS) monitoring in 72 adult patients. Change in blood pressure, induction time, and dose of propofol were compared among 3 groups. Results: The decreases in systolic and mean arterial pressure were statistically significant in the P200 group (P = 0.001, P = 0.014 respectively). Systolic blood pressure decreased significantly as the infusion rate increased. Diastolic blood pressure did not change in either group. The duration of induction was shortest with 400 mL h-1 infusion rate (177 s in P200, 182 s in P300, 134 s* in P400,*P = 0.003) and the total propofol dose was significantly higher in these patients (2.32 mg kg-1 in P200, 2.64 mg kg-1 in P300 , 2.85* mg kg-1 in P400, *P = 0.012). Conclusion: The induction dose required for loss of consciousness increased with a faster rate of infusion while time for induction was shorter in P400 compared to P200 and P300, and the decrease in mean blood pressure was less after induction in P200. Propofol injection should be slow enough to prevent any hemodynamic deterioration in anesthesia induction.
Breast cancer in Accra, Ghana

The aim of this study was to look at the pattern of breast cancer over a period of five years and to compare the findings to similar studies done in the Department and elsewhere within the African sub-region. All breast cancers diagnosed in the Department of Pathology of the Korle Bu Teaching Hospital, Accra, over a 5-year period were compiled. The slides for the cases were retrieved and reviewed. Invasive ductal carcinomas were graded according to the Scarff-Bloom-Richardson’s grading system. The data were entered and analyzed using the EPI-Info microcomputer software (Version 3.5.1, 2008, Center for Disease Control and Prevention (CDC) Atlanta). Breast cancer in Accra is mostly of the ductal type or its variants affecting relatively younger age groups. The mean age of incidence of cancer in Ghana is 48 years, and about 67% have lymph node metastases (at least Stage II or N1) and 74% are of high grade at the time of diagnoses. The percentage of male breast cancers in Ghana is 2.9% (2.0 - 3.75% within the West African sub-region) and is higher than what is reported in Western literature. The results of this study show that there has been no im-provement in the stage at which patients present with breast cancer in the past 30 years. Keywords : Breast cancer, cancer types, cancer grade, lymph node status, Accra
Frequency of Carriers for Beta Thalassemia and Sickle Cell Trait in Mersin

B AC K G R O U N D The aim of this study to determine frequency of carriers for β thalassemia and sickle cell trait in the people who applied to the Mersin P r o f . D r . Muzaffer Aksoy Diagnosis Center for the Genetic Blood Diseases. M ET H O D S People who applied to Mersin center station and the stations at the seven districts in between 2nd February 1999 and 1st February 2000 were included in the study. The complete blood count and the haemoglobin electrophoresis were performed in all applicants. R E S U LT S The study were included 12.173 people of those 50% were male and 50% were female. It was found that 2.3% of the participants are the carriers of β thalassemia, 1.3% are the carriers of the sickle cell trait. There were not significant relationship between the disease frequencies and the sexes. CO N C L U S I O N S A cc o rding to the data of the Ministry of Health, β thalass em ia carrying rate of the healthy pop ul at ion of Turkey is 2.1%. The prem ar ital screening tests are the imp o rt a n t protect ive health serv ices in det e rm ining the carr iers and a v o iding the births of the carr ier or sick children. With the help of the prem ar ital screening program performing in Mersin, it is exp e cted that the haemogl ob in opathy freq uency will red uce throughout the foll owing years.
Development of micronutrients rich homemade extruded food products with the incorporation of processed foxtail millet, wheat and chickpea.

Background: Food based approaches are recognized as an essential part of an urgently needed more comprehensive strategy for improving nutrition by increasing the availability and consumption to combat iron and other micronutrient deficiencies. Aims & Objective: The specific objective of the study was utilization of Foxtail millet (Setariaitalica) along with other flour for production of micronutrients rich ready-to-eat snack products using homemade extrusion cooking. Material and methods: Methods Composite flour were prepared using processed Foxtail millet flour (FMF) and other processed flours namely; wheat flour (WF), and chick pea flour (CPF). Nutritional properties of the blends were analyzed by using standard procedure. Two homemade extruded products namely; namkeensev, seviyan were prepared with four treatments T0, T1, T2, & T3. The commonly consumed recipes were developed by incorporating 50%, 75% and 100% of best result malted composite flour (FMF+CPF+WF). Results: The organoleptic qualities of these extruded samples were analyzed by panelists on a 9 point hedonic scale. The result indicate that the processed composite flour (FMF+CPF+WF) based products were significantly accepted at the level of p<0.05 50% incorporation followed by 75% and 100% respectively. Conclusions: The present study conclude that, processed composite flour (Foxtail millet; wheat; chickpea) in the ratios of (50:50) could be used to produce nutritive quality of homemade extrudates with acceptable sensory properties as they deliver vehicles for malnourished children.
Aktivitas Salep Ekstrak Rimpang Kunyit dalam Proses Persembuhan Luka pada Mencit yang Diinduksi Diabetes (THE ACTIVITY OF TURMERIC EXTRACT OINTMENT IN THE WOUND HEALING PROCESS OF INDUCED DIABETIC MICE)

The aim of this study was to evaluate the effectiveness of ethanol turmeric extract ointment in woundhealing process of streptozotocin-induced diabetic mice. Ethyl acetate and hexane fractions of ethanolturmeric extract were studied for their wound-healing properties in the formulation of ointment. Sixty micewere divided into 4 groups : group I was control (normal control, without treatment); group II was diabeticgroup (diabetic, without treatment); group III was diabetic and treated with ethyl acetate fraction ointment,group IV was diabetic and treated with hexane fraction ointment. The diabetic groups were i.p injectedwith 40mg/kg of streptozotocin and all groups were received incision 2 cm on their back skin. The ointmentsof ethyl acetate and hexane fraction were given topically twice a day. Three mice from each groups werenecropsied at 2nd, 4th, 7th, 14th and 21st days post incision (pi) for gross pathological and histopathologicalevaluation of the injured skin. Gross examination revealed that the ethyl acetate and hexane fractionointment groups showed better result on wound-healing process compared to the diabetic group.Microscopically, the ethyl acetate and hexane fraction ointment groups showed faster neovascularizationand reepithelialization compared to the diabetic group. In comparison with the diabetic group, the ethylacetate and hexane fraction ointment groups showed fewer neutrophils infiltration which indicated antiinflammatory activities of ethyl acetate and hexane fractions. Based on the macroscopic and microscopicobservation, the ointments of ethyl acetate and hexane fraction have properties to promote wound healingin diabetic mice.
Interactive Art Therapy: No Talent Required Projects

* Foreword (Lorna Hecker) * Preface * Acknowledgments * Introduction * Chapter 1. Theoretical Foundation for Interactive Art Therapy * Dual-Coding Theory * Contiguity Effect * Applications for Interactive Art Therapy * Chapter 2. Cage of Fears * Objective * Rationale * Cage of Fears Exercise Instructions * Vignette * Suggestions for Follow-Up * Contraindications for Use * Chapter 3. Teeter-Totter of Decision Making * Objective * Rationale * Teeter-Totter of Decision Making Exercise Instructions * Vignette * Suggestions for Follow-Up * Contraindications for Use * Chapter 4. The Coping Arch * Objective * Rationale * The Coping Arch Exercise Instructions * Vignette * Suggestions for Follow-Up * Contraindications for Use * Chapter 5. Boundary Castle * Objective * Rationale * Boundary Castle Exercise Instructions * Vignette * Suggestions for Follow-Up * Contraindications for Use * Chapter 6. Well of Needs * Objective * Rationale * Well of Needs Exercise Instructions * Vignette * Suggestions for Follow-Up * Contraindications for Use * Chapter 7. Weight of the World * Objective * Rationale * Weight of the World Exercise Instructions * Vignette * Suggestions for Follow-Up * Contraindications for Use * Chapter 8. Swamp of Sympathy * Objective * Rationale * Swamp of Sympathy Exercise Instructions * Vignette * Suggestions for Follow-Up * Contraindications for Use * Chapter 9. Brick Wall of Barriers * Objective * Rationale * Brick Wall of Barriers Exercise Instructions * Vignette * Suggestions for Follow-Up * Contraindications for Use * Chapter 10. Bloom Where You're Planted * Objective * Rationale * Bloom Where You're Planted Exercise Instructions * Vignette * Suggestions for Follow-Up * Contraindications for Use * Chapter 11. The Pressure Box * Objective * Rationale * The Pressure Box Exercise Instructions * Vignette * Suggestions for Follow-Up * Contraindications for Use * Chapter 12. Fisherman's Wharf * Objective * Rationale * Fisherman's Wharf Exercise Instructions * Vignette * Suggestions for Follow-Up * Contraindications for Use * Chapter 13. Pole Vault for Goals * Objective * Rationale * Pole Vault for Goals Exercise Instructions * Vignette * Suggestions for Follow-Up * Contraindications for Use * Chapter 14. The Spider Web * Objective * Rationale * The Spider Web Exercise Instructions * Vignette * Suggestions for Follow-Up * Contraindications for Use * Chapter 15. The Cracked Vase * Objective * Rationale * The Cracked Vase Exercise Instructions * Vignette * Suggestions for Follow-Up * Contraindications for Use * Epilogue * References * Index