Miracle-dz/UniFAR-FTUs huggingface dataset:
Performance Evaluation of EOG based HCI Application using Power Spectral Density based Features

Interestingly, in recent years active research is going on in the area of signal processing using Electrooculography signals (EOG). The reason behind this lies in the fact that the eye signal remains intact even though most of the body parts fail to function normally. In this context, the eye movements can be used to interact with the computers, hence leading to the need for human computer interface (HCI) development. This paper considers four basic tasks like blinking, reading, eyes closed and open for task based classification. Here, horizontal and vertical EOG signals derived from a group of healthy volunteers are considered. Power spectral density (psd) based features are extracted and are used to classify the four basic tasks. As a pilot study, k nearest neighbor (kNN classifier) and linear discriminant analysis (LDA) has been used. The results indicate that the highest classification accuracy is obtained using Yule Walker’s estimation for vertical EOG. Also, performance of the kNN using three nearest neighbors stands out the best possibility with the classification accuracy of 81.87%. Also, the results rule out the possibility of using linear discriminant analysis for the task based classification using EOG signals.
Early postoperative mortality similar between cemented and uncemented hip arthroplasty: a register study based on Finnish national data

Background and purpose — Implant survival of cemented total hip arthroplasty (THA) in elderly patients is higher than that of uncemented THA. However, a higher mortality rate in patients undergoing cemented THA compared with uncemented or hybrid THA has been reported. We assessed whether cemented fixation increases peri- or early postoperative mortality compared with uncemented and hybrid THA. Patients and methods — Patients with osteoarthritis who received a primary THA in Finland between 1998 and 2013 were identified from the PERFECT database of the National Institute for Health and Welfare in Finland. Definitive data on fixation method and comorbidities were available for 62,221 THAs. Mortality adjusted for fixation method, sex, age group, and comorbidities among the cemented, uncemented, and hybrid THA was examined using logistic regression analysis. Reasons for cardiovascular death within 90 days since the index procedure were extracted from the national Causes of Death Statistics and assessed separately. Results — 1- to 2-day adjusted mortality after cemented THA was comparable to that of the uncemented THA group (OR 1.2; 95% CI 0.24–6.5). 3- to 10-day mortality in the cemented THA group was comparable to that in the uncemented THA group (OR 0.54; CI 0.26–1.1), and in the hybrid THA group (OR 0.64, CI 0.25–1.6). Pulmonary embolism or cardiovascular reasons as a cause of death were not over-represented in the cemented THA group. Interpretation — Early peri- and postoperative mortality in the cemented THA group was similar compared with that of the hybrid and uncemented groups.
A theoretical explanation of the Piper-Steenbjerg effect

The relation bet^'een plant yield and plant nutrient concentration is sometimes found to be negative, a phenomenon called the Piper-Steenbjerg (PS) effect. A model was used to examine the underlying causes of the PS effect, and the conditions under which it is most likely to occur. The model uses the nutrient productivity concept for plant growth and a nutrient uptake equation in which root growth rate and external nutrient concentration determine the uptake rate. The study suggests that the PS effect occurs when the fast growth of plants grown in an initially higher nutrient medium eventually leads to a more rapid depletion of external nutrients than the slow growth of plants grown in an initially lower nutrient medium. The fast grovî th of plants combined with a rapid decrease of nutrient uptake leads to a fall in plant nutrient concentration. When these large plants with very low nutrient concentrations are compared with the smaller, slow-growing plants, a PS effect may be found depending on the time at which the plants are harvested, and on the range of initial values of the external nutrient content. When it occurs, the effect is greatest when the depletion volume per unit new root (Vj) is lowest, and when the mobility of nutrients in the medium is highest (a=l). The results are sufficiently general to apply to a variety of nutrients, plant species and growth media. Key-words: growth; model; nutrient productivity; PiperSteenbjerg; uptake.
Modifying UTAUT and innovation diffusion theory to reveal online shopping behavior

This study adapted the Unified Theory of Acceptance and Use of Technology (UTAUT) and innovation diffusion to show how virtual community building, website performance expectancy, effort expectancy, trialability, and two mediators (familiarity and perceived risk) interact and affect online shopping intention. A total of 430 valid participants were collected, all of whom had the goal of buying a smart phone. The results of the structural equation model analysis show that performance expectancy and effort expectancy positively affect website familiarity; virtual community building and trialability positively influence product familiarity; and perceived risk negatively affects purchase intention. In addition to the effects demonstrated by the regression results, website familiarity and product familiarity also have mediation effects. Finally, this study suggests that managers should provide a complete community to consumers in order to enable them to share information; furthermore, they should also provide details of product trials on the website, so that consumers can increase their familiarity with both the website and the products, as this can then raise consumer purchase intention.
The Effect of Aloe vera Extract on Adherence of Candida albicans and Other Properties of Heat Cure Denture Soft Lining Material

Objective: One of the serious drawbacks of denture soft lining materials is colonization by Candida albicans that might eventually leads to denture stomatitis. This can be treated either systemically or locally. With the recent increase interest in medicinal plants, this study aimed to evaluate the effect of Aloe vera powder incorporated with heat cure acrylic soft-liner powder on the adherence of Candida albicans, shear bond strength and tear strength. Methods: According to the results of pilot study, two percentages (3% and 10%) of aloe vera powder was used. Candida adherence test, shear bond strength and tear strength tests were performed, also the long-term effect was evaluated after 2 and 4 weeks incubation in artificial saliva. All data was analyzed using SPSS software (version 24). Descriptive and inferential statistics, ANOVA test with post-hoc analysis was applied. Results: The results indicated that both concentrations of aloe vera showed a statistically highly significant decrease in Candida albicans cell count in comparison to control group, also a significant increase in shear bond strength and non-significant difference in tear strength of soft liner for the experimental groups. After 2 and 4 weeks incubation in artificial saliva, all experimental groups showed a statistically significant decrease in Candida albicans cell count and a statistically significant increase in shear bond strength and tear strength test. Conclusion: Incorporation of aloe vera powder with heat cure acrylic soft-liner powder helps to add an anti-candidal property to the soft liner, also this addition results in improvement in shear bond strength and tear strength.
The Use of Coding Methods to Estimate the Social Behavior Directed toward Peers and Adults of Preschoolers with ASD in TEACCH, LEAP, and Eclectic “BAU” Classrooms

Momentary time sampling, partial-interval recording, and event coding are observational coding methods commonly used to examine the social and challenging behaviors of children at risk for or with developmental delays or disabilities. Yet there is limited research comparing the accuracy of and relationship between these three coding methods. By coding the low-frequency social behaviors of 100 preschool-aged children with autism spectrum disorder, the current study examines the associations among the three methodologies. Results indicated a strong relationship among all three coding methodologies. The findings provide information to researchers and practitioners considering the benefits and drawbacks of each coding methodology.
Genome-wide SNPs analysis of indigenous Zebu breeds in Pakistan

Prospects of high throughput technology in animal genetics makes easy to investigate hidden genetic variation in farm animal's genetic resources. However, many SNPs technologies are currently practicing in animal genetics. In this study, we investigated genome wide SNPs variations and its distribution across the indigenous cattle population in Pakistan using Illumina Bovine HD (777K) SNPs bead chip. A total of 136 individuals from ten different breeds were genotyped and after filtration 500, 939 SNPs markers were used for further analysis. The mean minor allele frequency (MAF) was 0.23, 0.20, 0.22, 0.22, 0.20, 0.18, 0.20, 0.22, 0.21 and 0.18 observed for Achi, Bhagnari, Cholistani, Dhanni, Dajal, Kankraj, Lohani, Red sindi, Sahiwal and Tharparkar cattle, respectively. Significant difference (P 0.05) within breeds and remaining 36% were considered as monomorphic markers. Average observed (Ho) and expected (HE) heterozygosity values 0.662 and 0.640 were estimated among these breeds. In conclusion, this preliminary study results revealed that these SNPs variation level could potentially be used for genetic characterization of zebu cattle breeds and could also be used to estimate genetic potential of these cattle breeds for livestock improvement in country.
An Interrupted Continuum of Care? What are the Risk Factors andComorbidities Related to Long-Term Engagement and Retention in HIVCare?

Despite the importance of continuous care, a large proportion of persons with HIV are not engaged or retained in care at any one time, leading to poor outcomes. Identifying the risk factors associated with lack of engagement and retention in HIV care is needed in order to target patients for interventions. While both engagement and retention in care have been studied using multiple measures, the observation period for the majority of studies is less than one year, few studies have examined both initial engagement and retention, and the effect of comorbidities has typically not been included. This study extends the literature by examining how comorbidities, in addition to demographics, HIV clinical indicators and transmission risk factors, were associated with engagement and retention in a cohort study of 485 HIV-infected persons seen for an initial HIV visit at an urban safety-net hospital. Using the electronic medical record, demographic, risk factor, health status and comorbidity data were gathered at the time of initial visits. To measure engagement and retention, appointment data were obtained for a 24-month period following the initial visit. Key findings were that unknown HIV transmission risk factor and being homeless at initial visit were associated with both lack of engagement and retention. Conversely being diagnosed with a psychiatric disorder was predictive of retention. Our findings have important implications for program structure, including the integration of care, as well as regarding key components to be addressed holistically in early clinic visits.
Modeling and comparison of superconducting linear actuators for highly dynamic motion

This paper presents a numerical modeling method for AC losses in highly dynamic linear actuators with high temperature superconducting (HTS) tapes. The AC losses and generated force of two actuators, with different placement of the cryostats, are compared. In these actuators, the main loss component in the superconducting tapes are hysteresis losses, which result from both the non-sinusoidal phase currents and movement of the permanent magnets. The modeling method, based on the H-formulation of the magnetic fields, takes into account permanent magnetization and movement of permanent magnets. Calculated losses as function of the peak phase current of both superconducting actuators are compared to those of an equivalent non-cryogenic actuator.
Buckling optimization of composite laminates using a hybrid algorithm under Puck failure criterion constraint

In this study, an optimization procedure is proposed to find the optimum stacking sequence designs of laminated composite plates in different fiber angle domains for maximum buckling resistance. A hybrid algorithm combining genetic algorithm and trust region reflective algorithm is used in the optimization to obtain higher performance and improve the quality of solutions. As a novelty, Puck fiber and inter-fiber failure criteria are directly implemented to the optimization problems as nonlinear function constraints, which have allowed more consistent and feasible results. The performance of the hybrid algorithm is demonstrated by comparing with the individual performances of genetic and trust region reflective algorithms via test problems from the literature. Also, a study is performed to exhibit the effectiveness of the selected failure criterion as constraint among the other common criteria. The proposed procedure is used to solve many problems including various design considerations. The results indicate that reliable stacking sequence designs can be achieved in specific configurations even for the composite plates subjected to superior buckling loads when Puck physically based (3D) failure theory is considered as a first ply failure constraint in the buckling optimization.
Sustained MK-801 induced deficit in a novel probabilistic reversal learning task

Cognitive flexibility, the ability to adapt to unexpected changes, is critical for healthy environmental and social interactions, and thus to everyday functioning. In neuropsychiatric diseases, cognitive flexibility is often impaired and treatment options are lacking. Probabilistic reversal learning (PRL) is commonly used to measure cognitive flexibility in rodents and humans. In PRL tasks, subjects must sample choice options and, from probabilistic feedback, find the current best choice which then changes without warning. However, in rodents, pharmacological models of human cognitive impairment tend to disrupt only the first (or few) of several contingency reversals, making quantitative assessment of behavioral effects difficult. To address this limitation, we developed a novel rat PRL where reversals occur at relatively long intervals in time that demonstrates increased sensitivity to the non-competitive NMDA receptor antagonist MK-801. Here, we quantitively compare behavior in time-based PRL with a widely used task where reversals occur based on choice behavior. In time-based PRL, MK-801 induced sustained reversal learning deficits both in time and across reversal blocks but, at the same dose, only transient weak effects in performance-based PRL. Moreover, time-based PRL yielded better estimates of behavior and reinforcement learning model parameters, which opens meaningful pharmacological windows to efficiently test and develop novel drugs preclinically with the goal of improving cognitive impairment in human patients.
An Overview of Artificial Intelligence in Education

Artificial Intelligence (AI) has been introduced into education to enhance teaching and learning. The development of AI assisted teaching and learning practices and outcomes has gained increased interest among researchers and educators. For example, AI supported “smart” tutoring systems have been used to assist learning in higher education and K-12 settings. The support of technology infusion in education has made it possible for students and educators to experience AI embedded learning activities as part of advanced technology. The benefits of using AI in teaching and learning are many: AI works around-the-clock, never tires, and is always ready to assist a student. In this article, the application of AI embedded technology in education in the last five years is explored and discussed based on the literature.
Road map for fibrolamellar carcinoma: progress and goals of a diversified approach

Fibrolamellar carcinoma is a rare liver cancer, which primarily afflicts adolescents and young adults worldwide and is frequently lethal. Given the rarity of this disease, patient recruitment for clinical trials remains a challenge. In November 2017, the Second Fibrolamellar Cancer Foundation Scientific Summit (Stamford, CT, USA) provided an opportunity for investigators to discuss recent advances in the characterization of the disease and its surrounding liver and immune context. The Fibrolamellar Cancer Foundation has thus set out a road map to identify and test therapeutic targets in the most efficient possible manner.
EEG functional brain connectivity strengthens with age during attentional processing to faces in children

Studying functional connectivity may generate clues to the maturational changes that occur in children, expressed by the dynamical organization of the functional network assessed by electroencephalographic recordings (EEG). In the present study, we compared the EEG functional connectivity pattern estimated by linear cross-correlations of the electrical brain activity of three groups of children (6, 8, and 10 years of age) while performing odd-ball tasks containing facial stimuli that are chosen considering their importance in socioemotional contexts in everyday life. On the first task, the children were asked to identify the sex of faces, on the second, the instruction was to identify the happy expressions of the faces. We estimated the stable correlation pattern (SCP) by the average cross-correlation matrix obtained separately for the resting state and the task conditions and quantified the similarity of these average matrices comparing the different conditions. The accuracy improved with higher age. Although the topology of the SCPs showed high similarity across all ages, the two older groups showed a higher correlation between regions associated with the attentional and face processing networks compared to the youngest group. Only in the youngest group, the similarity metric decreased during the sex condition. In general, correlation values strengthened with age and during task performance compared to rest. Our findings indicate that there is a spatially extended stable brain network organization in children like that reported in adults. Lower similarity scores between several regions in the youngest children might indicate a lesser ability to cope with tasks. The brain regions associated with the attention and face networks presented higher synchronization across regions with increasing age, modulated by task demands.
Prevalence and antimicrobial resistance of Shigella species isolated from diarrheal patients in Ahvaz, southwest Iran

Introduction Shigellosis is a significant global human health problem, and Shigella is in charge of almost 165 million cases of this disease annually, of whom 163 million cases are in developing countries and 1.5 million cases are in developed countries. The main aims of the current survey were to identify Shigella spp. isolated from diarrheal patients by conventional biochemical tests, determine the antimicrobial susceptibility profiles by disk diffusion method, and detect the ipaH gene using the PCR assay. Methods The bacterial isolates were identified as Shigella spp. by microbiological tests and were serogrouped by the slide agglutination test. Antimicrobial susceptibility testing was performed using the disk diffusion method. PCR was performed to detect the ipaH gene. Results The Shigella strains were isolated from 522 patients with various diarrhea, including bloody diarrhea (3%), mucoid plus bloody diarrhea (1.9%), mucoid diarrhea (3.2%), and watery diarrhea (3.2%). Overall, 69 (13.2%) isolates were positive for Shigella spp. , of which 34 (49.3%) serotypes were identified as Shigella flexneri, 22 (31.9%) serotypes were identified as Shigella sonnei, 9 (13%) serotypes were identified as Shigella boydii, and 4 (5.8%) serotypes were identified as Shigella dysenteriae. Antibiotic susceptibility tests revealed that the highest resistance percentage was related to ampicillin (82%) and trimethoprim-sulfamethoxazole (77%), and ciprofloxacin and ceftriaxone were the best antibiotics against Shigella isolates. Conclusion We concluded that Shigella spp. can be considered as an etiological agent of diarrhea in southwest Iran. Since the drug resistance pattern of Shigella differs geographically and over time within a country, continuous and regular surveillance program is necessary.
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Pharyngeal pathology in a mouse model of oculopharyngeal muscular dystrophy is associated with impaired basal autophagy in myoblasts

Oculopharyngeal muscular dystrophy (OPMD) is a late-onset dominant disease that primarily affects craniofacial muscles. Despite the fact that the genetic cause of OPMD is known to be expansion mutations in the gene encoding the nuclear polyadenosine RNA binding protein PABPN1, the molecular mechanisms of pathology are unknown and no pharmacologic treatments are available. Due to the limited availability of patient tissues, several animal models have been employed to study the pathology of OPMD. However, none of these models have demonstrated functional deficits in the muscles of the pharynx, which are predominantly affected by OPMD. Here, we used a knock-in mouse model of OPMD, Pabpn1 +/A17 , that closely genocopies patients. In Pabpn1 +/A17 mice, we detected impaired pharyngeal muscle function, and impaired pharyngeal satellite cell proliferation and fusion. Molecular studies revealed that basal autophagy, which is required for normal satellite cell function, is higher in pharynx-derived myoblasts than in myoblasts derived from limb muscles. Interestingly, basal autophagy is impaired in cells derived from Pabpn1 +/A17 mice. Pabpn1 knockdown in pharyngeal myoblasts failed to recapitulate the autophagy defect detected in Pabpn1 +/A17 myoblasts suggesting that loss of PABPN1 function does not contribute to the basal autophagy defect. Taken together, these studies provide the first evidence for pharyngeal muscle and satellite cell pathology in a mouse model of OPMD and suggest that aberrant gain of PABPN1 function contributes to the craniofacial pathology in OPMD.
Self-organization in amoeboid motility

Amoeboid motility has come to refer to a spectrum of cell migration modes enabling a cell to move in the absence of strong, specific adhesion. To do so, cells have evolved a range of motile surface movements whose physical principles are now coming into view. In response to external cues, many cells—and some single-celled-organisms—have the capacity to turn off their default migration mode. and switch to an amoeboid mode. This implies a restructuring of the migration machinery at the cell scale and suggests a close link between cell polarization and migration mediated by self-organizing mechanisms. Here, I review recent theoretical models with the aim of providing an integrative, physical picture of amoeboid migration.