Miracle-dz/UniFAR-FTUs huggingface dataset:
Work Environment Perception as a Predictor of Patient Safety Culture among Nurses at Al-Ahrar Teaching Hospital

Background: patient safety is a basic goal of all healthcare organizations. One of the bigger knowledge gaps is how workplace factors influence safety outcomes. The aim of the study: was to assess work environment perception as a predictor of patient safety culture among nurses at AlAhrar Teaching Hospital. Subjects & methods: Research design: A descriptive cross-sectional survey design. Setting: This study was conducted at Al-AhrarTeachingHospital, SharqiaGovernorate,-Egypt. Subjects: Convenience samples of 345 nursing staff members. Tools of data collection: A self-administered questionnaire sheets were used for data collection: 1) personal data. 2) Work environment scale which includes 31 items categorized into the following five subscales: nurse participation in hospital affairs (nine items); nurse manager ability, leadership, and support of nurses (five items); nurse foundations for quality of care (ten items); collegial nurse–physician relations (three items); and staffing and resource adequacy (four items). 3) Patient safety culture survey which includes 12 dimensions. Results: revealed that, there was highly statistically significant relation (P= 0.000) between the nurses' perception regarding their work environment and their perception regarding patient safety culture. Conclusion: Improving the patient safety culture among nurses may be achieved through an enhancement their work environment perception. Recommendations: Improving the nursing practice environment using several measures, and in-service training program about nurse practice environment and patient safety for studied nurses should be conducted.
Pengaruh Minat dan Motivasi Belajar Terhadap Prestasi Belajar Matematika

The purpose of this study is to. Knowing the influence of learning motivation and interest towards achievement of Junior High School students learn math in Karawaci subdistrict of Tangerang. The sample used in the 63 students who get with a random sampling technique. The collection of data by questionnaire (question form) to gauge interest and motivation to learn, while learning math achievement is taken from the value of the UAS. Test results whose hypotheses, namely 1) find out the influence of the interest and motivation of learning together towards the achievement of Junior High School students learn math in Karawaci subdistrict of Tangerang. 2) know how the learning interest towards achievement of Junior High School students learn math in Karawaci subdistrict of Tangerang. 3) know how the learning motivation toward achievement of Junior High School students learn math in Karawaci subdistrict of Tangerang.
Magnitude and Sources of Sediment Input to the Mackenzie Delta, Northwest Territories, 1974-94

Hydrometric and sediment data collected by Environment Canada in the Mackenzie Basin during the period 1974-94 have been analyzed to produce detailed estimates of sediment inputs to the Mackenzie Delta, based largely on sediment rating equations. The mean annual sediment supply to the delta is determined as 128 million tonnes (Mt), of which about 4 Mt is sandy bed material moved in by the Mackenzie River itself. Virtually all of this sediment (more than 99%) is supplied to the delta during the May-October period, the peak months being May (27%), June (36%), and July (19%). About 17% of the fine-sediment load is supplied by the Peel River; the rest is delivered by the Mackenzie. The largest single contributor to the Mackenzie River wash load (103 Mt) is the Liard River (41 Mt). The preliminary estimate of the contribution of the other west-bank tributaries, in combination, is about 36 Mt, though this figure is probably too low. The precision of these estimates using the sediment rating approach (compared to time-integration during months with reasonable sampling frequency) is about 10% for the mean monthly sediment loads and about 5% for the mean annual sediment load during the 1974-94 period. The absolute accuracy of sediment load estimates is more difficult to assess because published flow data for delta inflow stations are acknowledged to be much less reliable for the spring breakup period than for other times of the year. Key words: Mackenzie Delta, sediment loads, rivers
The Comparison of the Number of Citations by Articles in Different Scientific Fields

This paper explores the possibility of making meaningful comparisons of the number of citations received by articles in sub-fields identified with the 219 Web of Science categories distinguished by Thomson Scientific. Such comparisons are instrumented on the basis of: (i) the assumption that articles at the same quantileof any sub-field citation distribution have the same degree of citation impact in their respective sub-field, and (ii) strong similarities found in the behavior of citation distributions in a large quantile interval. Three aims are achieved. Firstly, we answer how many citations for an article in the interval between, approximately, the 75 and the 97 percentiles in any sub-field are equivalent to 10 citations in the reference sub-field, Physics, Condensed Matter. The answer, in terms of what we call exchange rates, is very satisfactory for 203 out of 219 sub-fields. Secondly, the associated sub-field normalization procedure performs well in that interval. Thirdly, we provide an empirical explanation of why sub-field mean citations can be equally successfully used for both purposes.
Some Spectral Sequences for Filtered Complexes and Applications

Abstract We construct a hierarchy of spectral sequences for a filtered complex under a left-exact functor. As applications we prove (1) the existence of a Leray spectral sequence for de Rham cohomology, (2) the equivalence of this sequence with the “usual” Leray spectral spectral sequence under the comparison isomorphism, and (3) the isomorphism of the Bloch–Ogus spectral sequence with the Leray spectral sequence for the morphism from the fine site to the Zariski site.
Hospital-Acquired Hyponatremia in Children Following Hypotonic versus Isotonic Intravenous Fluids Infusion

Hypotonic solutions have been used in pediatrics for maintenance of intravenous (IV) hydration. However, recent randomized control trials and cohort studies have raised significant concerns for association with hospital-acquired hyponatremia (HAH). The study aimed to assess whether the use of hypotonic parenteral solutions (PS) compared with isotonic PS is associated with increased HAH risk in children with common pediatric conditions. Retrospective chart review of 472 patients aged 2 months to 18 years who received either isotonic or hypotonic PS as maintenance fluids. Administration of hypotonic PS was associated with a four-fold increase in risk of developing HAH in the univariate analysis, (unadjusted odds ratio (OR) = 3.99; 95% confidence interval (CI): 1.36–11.69, p = 0.01). Hypotonic PS were associated with HAH (p = 0.04) when adjusted for the level of admission serum CO2. There was a mean decrease of serum sodium of 0.53 mEq/L in the hypotonic group compared to the mean increase of 4.88 mEq/L in the isotonic group. These data suggest that hypotonic PS are associated with HAH in children admitted for common pediatric conditions. Isotonic PS should be considered as a safer choice for maintenance fluid hydration.
Knee Stiffness After Tibial Plateau Fractures: Predictors and Outcomes (OTA-41)

Objectives: What patient characteristics and injury factors predict decreased knee range of motion (ROM) after operative management of tibial plateau fractures? Design: Prospective cohort study. Setting: Academic medical center. Patients: Over 11 years, tibial plateau fractures at a single academic institution were prospectively followed. A total of 266 patients were included in this study. Intervention: Surgical repair of tibial plateau fractures and secondary interventions due to arthrofibrosis. Main outcome measure: Clinical outcomes were evaluated using the Short Musculoskeletal Function Assessment and ROM at 3-month, 6-month, and long-term follow-up. Secondary outcomes were considered as the need for a subsequent procedure due to arthrofibrosis. Results: At 3-month follow-up, the mean ROM was 113 degrees. By long-term follow-up (mean = 17 months), the mean ROM improved to 125 degrees. Independent predictors of decreased knee ROM were the following: at 3-month follow-up, open fractures (P = 0.047), application of a knee-spanning external fixator (P = 0.026), orthopaedic polytrauma (P = 0.003), and tibial spine involvement (P = 0.043); and at long-term follow-up, nonwhite ethnicity (P = 0.003), increasing age (P = 0.003), and a deep infection (P = 0.002). Ten patients (3.7%) required a secondary procedure for arthrofibrosis. There was a significant improvement in the knee ROM (P < 0.001) and functional outcomes (P = 0.004) following the intervention. Conclusions: At long-term follow-up, independent predictors of decreased knee ROM were nonwhite ethnicity, increasing age, and sustaining a postoperative complication of a deep infection. Secondary interventions were reliable treatments for arthrofibrosis. Level of Evidence: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Does nutritional status affect Parkinson's Disease features and quality of life?

Objectives The aim of this study was to determine the relationship between nutritional status and Parkinson's Disease (PD) features in association with depression, anxiety and quality of life in people with PD. Materials and methods This study was conducted on 96 patients with idiopathic PD to whom the following scales were applied: Unified Parkinson’s Disease Rating Scale (UPDRS), 39-item PD questionnaire (PDQ-39), Hospital Anxiety and Depression Score (HADS), Mini Nutritional Assessment (MNA). The scales and measurements were applied to patients at their first assessment. Patients with malnutrition or at risk of malnutrition were assessed by the dietitian and nutrition nurse. These patients received nutritional support through personalized diet recommendations and appropriate enteral nutritional products, considering factors such as age, comorbidity, socioeconomic and cultural conditions. At the end of 6 weeks, the scales and measurements applied during the first visit were again applied to the patients. Results A significant and inverse correlation was determined between mental (Spearman r:-0.510, p<0.001), activities of daily living (Spearman r:-0.520, p<0.001), motor (Spearman r:-0.480, p<0.001), complications (Spearman r:-0.346, p<0.001) UPDRS subdivisions and total scores (Spearman r:-0.644, p<0.001) and total MNA score. A significant and inverse correlation was found between all PDQ-39 subdomains and total MNA score (p<0.05). The highest inverse correlations were found in mobility (Spearman r:-0.690, p<0.001) and stigma (Spearman r:-0.570, p<0.001). Both depression (Spearman r:-0.631, p<0.001) and anxiety (Spearman r:-0.333, p<0.001) scores were determined to be inversely correlated with total MNA score. At the 6-week control visit, significantly lower scores were found in all subdivisions and in the total UPDRS score, PDQ-39 score and in the patients' anxiety and depression scores (p<0.05). MNA scores were found to be significantly higher in the assessment performed after 6 weeks of support for patients who had abnormal nutritional status at inception (p<0.001). Conclusion PD motor and nonmotor functions, disease duration and severity are related to nutritional status. Quality of life was also shown to be affected by changes in the nutritional status. These results show that nutritional status assessment should be a standard approach in the PD treatment and follow-up processes.
CEM-RL: Combining evolutionary and gradient-based methods for policy search

Deep neuroevolution and deep reinforcement learning (deep RL) algorithms are two popular approaches to policy search. The former is widely applicable and rather stable, but suffers from low sample efficiency. By contrast, the latter is more sample efficient, but the most sample efficient variants are also rather unstable and highly sensitive to hyper-parameter setting. So far, these families of methods have mostly been compared as competing tools. However, an emerging approach consists in combining them so as to get the best of both worlds. Two previously existing combinations use either an ad hoc evolutionary algorithm or a goal exploration process together with the Deep Deterministic Policy Gradient (DDPG) algorithm, a sample efficient off-policy deep RL algorithm. In this paper, we propose a different combination scheme using the simple cross-entropy method (CEM) and Twin Delayed Deep Deterministic policy gradient (td3), another off-policy deep RL algorithm which improves over ddpg. We evaluate the resulting method, cem-rl, on a set of benchmarks classically used in deep RL. We show that cem-rl benefits from several advantages over its competitors and offers a satisfactory trade-off between performance and sample efficiency.
Meta-analysis of the likelihood of FOXC2 expression in early- and late-stage tumors

Background Aberrations in the expression of the transcription factor forkhead box C2 (FOXC2) have been linked to a number of malignancies. Here, we characterized the relationship between FOXC2 and cancer progression by conducting a meta-analysis of studies that reported the frequency of FOXC2 expression in tumors of different stages (T1, T2, T3, T4). Methods Relevant articles were retrieved from the Medline database by searching for the terms “FOXC2” and “cancer”; then, the retrieved articles were reviewed individually, and studies that were of multivariate cohort design, evaluated FOXC2 expression via immunohistochemical staining, and assessed the relationship between FOXC2 expression and cancer T-stage were included in our meta-analysis. Results Our search terms identified 139 studies, 9 of which met all inclusion criteria. A total of 1433 tumor samples were evaluated in the 9 studies; 596 samples were from early-stage (T1-T2) tumors, and 838 were from late-stage (T3-T4) tumors. FOXC2 was expressed in 46.0% of all samples, in 32.4% of early-stage tumor samples, and in 55.6% of late-stage tumor samples. When calculated relative to early-stage samples, the pooled risk for FOXC2 expression in late-stage samples was 1.367 (95% CI = 1.103–1.695, p = 0.004). Conclusion The results from our meta-analysis of 9 studies indicate that FOXC2 is 36.7% more likely to be expressed in late-stage tumors than in early-stage tumors.
How UX Practitioners Produce Findings in Usability Testing

Usability testing has long been a core interest of HCI research and forms a key element of industry practice. Yet our knowledge of it harbours striking absences. There are few, if any detailed accounts of the contingent, material ways in which usability testing is actually practiced. Further, it is rare that industry practitioners’ testing work is treated as indigenous and particular (instead subordinated as a ‘compromised’ version). To service these problems, this article presents an ethnomethodological study of usability testing practices in a design consultancy. It unpacks how findings are produced in and as the work of observers analysing the test as it unfolds between moderators taking participants through relevant tasks. The study nuances conventional views of usability findings as straightforwardly ‘there to be found’ or ‘read off’ by competent evaluators. It explores how evaluators/observers collaboratively work to locate relevant troubles in the test's unfolding. However, in the course of doing this work, potential candidate troubles may also routinely be dissipated and effectively ‘ignored’ in one way or another. The implications of the study suggest refinements to current understandings of usability evaluations, and affirm the value to HCI in studying industry practitioners more deeply.
Radiopaque and uniform alginate microspheres loaded with tantalum nanoparticles for real-time imaging during transcatheter arterial embolization

One restriction to the development and application of transcatheter arterial chemoembolization (TACE) therapy is the lack of an inherently radiopaque embolic whose location and distribution can be precisely visualized in real time and be used for non-invasive examination after surgery. Methods: A one-step electrospray method was developed to fabricate calcium alginate microspheres loaded with tantalum nanoparticles (Ta@CaAlg). The parameters of electrospraying were assessed. The in vivo X-ray imaging capability and embolic effect of Ta@CaAlg microspheres were evaluated in the renal arteries of normal rabbits by digital radiography and computed tomography. Doxorubicin hydrochloride (Dox) was chosen as a model drug, and the drug loading capacity and release behavior of these microspheres was valuated in vitro. Results: Spherical Ta@CaAlg microspheres with monodisperse sizes ranging from 150 to 1200 μm were fabricated by electrospraying. The results of an in vivo study showed that Ta@CaAlg microspheres possessed the qualities of both embolic agents and contrast media. They could not only feed back the real-time location and distribution of the embolic microspheres but also maintained clear X-ray imaging of embolized sites for up to 4 weeks as assessed by digital radiography and computed tomography. Digital subtraction angiography showed that they had an excellent embolic effect. Ta@CaAlg microspheres could be loaded with Dox to form “3-in-1” embolic microspheres. The maximum Dox loading was 97.3 mg Dox per mL beads and loaded microspheres exhibited pH-dependent release profiles. Conclusion: The X-ray opacity and drug-loading capability of Ta@CaAlg microspheres offers great promise in direct, real-time, in vivo investigation for TACE and long-term non-invasive re-examination.
Association of miRNA-146a rs2910164 and miRNA-196 rs11614913 polymorphisms in patients with ulcerative colitis

Background: It has been reported that the single nucleotide polymorphisms (SNPs) miRNA-196 (miR-196) rs11614913 and miRNA-146a (miR-146a) rs2910164 are related to susceptibility to ulcerative colitis (UC). Because the previously reported results have been mixed and uncertain, the aim of this study was to perform a meta-analysis and review to assess the relationship between these 2 SNPs and UC risk. Methods: In this analysis, 5 studies involving 1023 cases and 1769 controls for miR-196 rs11614913 and 4 studies involving 827 cases and 1451 controls for miR-146 rs2910164 were included. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were used to pool the effect size. Results: A decreased risk of UC was identified in homozygote comparison (GG vs CC: OR = 0.69, 95% CI: 0.52–0.93, P = .02), recessive comparison (GG vs CG + CC: OR = 0.74, 95% CI: 0.59–0.92, P = .007), and dominant comparison (GG + CG vs CC: OR = 0.79, 95% CI: 0.65–0.97, P = .02) of miR-146 rs2910164 in Asian but not Caucasian population. No evidence of an association was shown between the rs11614913 polymorphism and UC risk in allelic, heterozygote, homozygote, recessive, and dominant models in both Caucasian and Asian populations (P > .05). Conclusions: MiR-146 rs2910164, but not miR-196 rs11614913, was associated with a decreased risk of UC in Asian population. However, the results should be treated with caution because of the limited sample size and heterogeneity. Well-designed studies with large sample sizes and more ethnic groups are needed to validate the risks identified in the current meta-analysis and review.
Isolation and Identification of the Five Novel Flavonoids from Genipa americana Leaves

Genipa americana is a medicinal plant popularly known as “jenipapo”, which occurs in Brazil and belongs to the Rubiaceae family. It is a species widely distributed in the tropical Central and South America, especially in the Cerrado biome. Their leaves and fruits are used as food and popularly in folk medicine to treat anemias, as an antidiarrheal, and anti-syphilitic. Iridoids are the main secondary metabolites described from G. americana, but few studies have been conducted with their leaves. In this study, the aim was to chemical approach for identify the main compounds present at the extract of G. americana leaves. The powdered leaves were extracted by maceration with EtOH: water (70:30, v/v), following liquid-liquid partition with petroleum ether, chloroform, ethyl acetate and n-butanol. A total of 13 compounds were identified. In addition three flavonoids were isolated from the ethyl acetate fraction: quercetin-3-O-robinoside (GAF 1), kaempferol-3-O-robinoside (GAF 2) and isorhamnetin-3-O-robinoside (GAF 3) and, from n-butanol fraction more two flavonoids were isolated, kaempferol-3-O-robinoside-7-O-rhamnoside (robinin) (GAF 4) and isorhamnetin-3-O-robinoside-7-rhamnoside (GAF 5). Chemical structures of these five flavonoids were elucidated using spectroscopic methods (MS, 1H and 13C-NMR 1D and 2D). These flavonoids glycosides were described for the first time in G. americana.
Super-Resolution via Conditional Implicit Maximum Likelihood Estimation

Single-image super-resolution (SISR) is a canonical problem with diverse applications. Leading methods like SRGAN produce images that contain various artifacts, such as high-frequency noise, hallucinated colours and shape distortions, which adversely affect the realism of the result. In this paper, we propose an alternative approach based on an extension of the method of Implicit Maximum Likelihood Estimation (IMLE). We demonstrate greater effectiveness at noise reduction and preservation of the original colours and shapes, yielding more realistic super-resolved images.
Age and leptinemia association with anxiety and depression symptoms in overweight middle-aged women

Objective: The aim of the study was to investigate the effect of menopause and of postmenopausal stages on depression and anxiety symptoms, and whether these symptoms associate with anthropometric, metabolic, and hormonal parameters in midlife women. Methods: Postmenopausal women (age 50-65), either at early (EPM, n=33) or late (LPM, n = 23) postmenopause, and 23 premenopausal controls (PreM, age 40-50), matched for BMI with the PM groups, were studied. Blood biochemical and hormonal determinations, bioimpedance anthropometry, and depression and anxiety symptoms (Beck's depression [BDI] and anxiety [BAI] inventories) were conducted. Results: The BAI score was higher in both PM groups than in the PreM group. In contrast, only the LPM group showed a significantly elevated BDI score. All groups presented overweight and abdominal obesity, having similar BMI and waist/hip ratio values. Both PM groups showed insulin resistance, whereas only the LPM group presented decreased skeletal muscle mass and basal metabolic rate. Correlation analysis, including all 79 middle-aged women, showed age, percentage body fat, waist/hip ratio, and leptinemia to correlate positively with the anxiety and depression scores. Multivariate regression showed leptin and age to associate positively with depressive- and anxious-like symptoms. Conclusions: Postmenopausal women presented impaired body composition, energy expenditure, insulin sensitivity, and mental symptoms, in comparison to similarly overweight premenopausal women. Among all the overweight midlife women, these symptoms were more strongly associated with age and leptin levels than with reproductive aging itself. The data indicate that, among overweight middle-aged women with abdominal obesity, the aging process and the development of leptin resistance are associated with impairment of mental health.