Miracle-dz/UniFAR-FTUs huggingface dataset:
Maternal serum soluble HLA-G in complicated pregnancies

Abstract Preeclampsia, intrauterine growth retardation (IUGR), oligohydramnios, abortus, preterm birth and premature rupture of the membranes (PROM) are significant complications of pregnancy. Insufficient trophoblastic invasion plays an important role in the pathophysiology of pregnancy complications. Soluble human leukocyte antigen-gestation (HLA-G)1/G5 is a molecule associated with trophoblast invasion. When pregnancy complications are predicted early, strategies to prevent these complications can be implemented. The aim of this study was to investigate the relationship between first trimester maternal serum soluble HLA-G1/G5 levels and high-risk pregnancies. A total of 232 pregnant women were followed prospectively. Maternal blood samples were collected for determination of soluble HLA-G1/G5 levels at 11–14 weeks, during which routine serum free beta human chorionic gonadotropin (βhCG) and pregnancy associated plasma protein-A (PAPP-A) level determinations in addition to nuchal translucency (NT) measurements for Down’s syndrome screening were done during 20–22 weeks gestation. The subjects were classified into normal pregnancy, preeclampsia, oligohydramnios, IUGR, preterm birth and PROM groups. First trimester maternal serum soluble HLA-G1/G5 levels were not significantly different between the groups. First trimester soluble HLA-G1/G5 did not predict high-risk pregnancies. Studies with larger number of cases are need to confirm our findings.
Histone deacetylase 3 is associated with gastric cancer cell growth via the miR-454-mediated targeting of CHD5

Gastric cancer (GC) is the third leading cause of cancer-related mortality in China and worlwide; hence, the identification of GC-related genes is necessary for the development of effective treatment strategies. In this study, histone deacetylase 3 (HDAC3) was identified as the most significantly upregulated cancer-related gene in GC tissues by microarray. In accordance with this, HDAC3 expression was found to be upregulated in GC cell lines/tissues. Further experiments indicated that the knockdown of HDAC3 decreased GC cell viability, reduced the colony formation number and decreased tumor weight. To explore the underlying mechanisms, the overexpression of HDAC3 was induced by transfection with an overexpression plasmid, followed by miRNA microarray, and we identified miR-454 as the most markedly upregulated miRNA. Accordingly, miR-454 expression was upregulated in GC cell lines/tissues and a high level of miR-454 indicated a high HDAC3 expression in GC tissues, and miR-454 knockdown reduced cell viability. In addition, a high level of miR-454 was significantly associated with an advanced clinical stage, lymph node metastases and a poor prognosis of patients with GC. Furthermore, CHD5 was identified as a direct target of miR-454. CHD5 was downregulated in GC tissues/cell lines and the expresssion of CHD5 inversely correlated with the level of miR-454 in GC tissues. Taken together, these observations indicate that HDAC3 is associated with GC cell growth via the miR-454-mediated targeting of CHD5.
Founders' credentials and performance of startups

Devarakonda Venkata Naga, Siva Ramakrishna. Ph.D., Purdue University, August 2015. Founders’ Credentials and the Performance of Startups. Major Professors: Thomas H. Brush and Jeffrey J. Reuer. In this dissertation, I unpack startup founders’ characteristics and investigate their impact on the performance of young high-tech startups. I distinguish specific aspects of founders that convey their unobservable quality and human capital, and advance new arguments that deepen our understanding about founders’ role in shaping the prospects and performance of young high-tech startups. In particular, I examine founders’ distinct technical and entrepreneurial credentials that have the effect of facilitating important milestones for startups, such as strategic alliances and initial public offering, which ensure startups’ growth and survival. Further, I also investigate the contingent effects of these credentials of startup founders on the degree of uncertainty that prevails for potential alliances partners and investors about startups’ underlying quality. In three essays that comprise this dissertation, I find evidence that startup founders’ scientific and entrepreneurial credentials promote favorable cooperative commercialization agreements for startups with alliances partners and accelerate their initial public offerings. I also find evidence that these distinct credentials of founders are more useful when there is higher uncertainty about startups’ quality. These findings have important implications for research in strategy and entrepreneurship about the significance and enduring impact of startups’
The Impact of Participation on Goal Acceptance and Performance: A Two-Step Model

Past research has tested goal setting strategies and found high and invariant levels of goal acceptance. The present research consisted of two studies—one laboratory and one field experiment—hypothesizing a two-step model (participation acceptance performance) with which participation could be tested more effectively. Stepwise, hierarchical regression analyses demonstrated that the participative and representative groups outperformed the assigned groups under conditions in which individual goal acceptance varied. The findings support the two-step model and offer an explanation as to why previous research has failed to differentiate empirically between participative and assigned goal setting.
Nucleolar protein B23 translocation after doxorubicin treatment in murine tumor cells.

Rats bearing Novikoff hepatoma ascites cells were given i.p. injections of actinomycin D, doxorubicin, or daunorubicin. Four hours after injection, tumor cells were removed from the ascites fluid and analyzed for protein B23 translocation using an immunofluorescence technique. Bright nucleolar fluorescence was observed in untreated cells. Treatment with actinomycin D (1.25 mg/kg), doxorubicin (25 mg/kg), or daunorubicin (12.5 mg/kg) produced a uniform nucleoplasmic fluorescence. This change in immunofluorescence distribution indicated that protein B23 translocated from the nucleolus to the nucleoplasm after drug treatment. These results are an extension of previous studies with HeLa cells (Yung et al., Cancer Res. 46: 922-925, 1986). Doxorubicin-resistant and -sensitive mouse leukemia cells (P388) were cultured in medium containing various doses of doxorubicin for 4 h, and the responsive levels of the cells to doxorubicin were compared. At 50 micrograms/ml doxorubicin, 86% of the doxorubicin-sensitive cells showed uniform nucleoplasmic fluorescence, and less than 2% of the cells retained nucleolar fluorescence. At this same dose, only 9% of the resistant cells showed nucleoplasmic fluorescence, and 75% of the cells retained nucleolar fluorescence. At 100 micrograms/ml, about 26% of the resistant cells showed translocation, in contrast to 100% of the sensitive cells that showed B23 translocation. About 57% of the resistant cells showed an intermediate effect, and about 17% of the resistant cells maintained bright nucleolar fluorescence at this dose. The resistant cells also showed less responsiveness to actinomycin D. These results suggest that identification of "B23 translocation" may be used to detect drug-resistant cells and to study the efficacy of certain antitumor agents.
Control Combinations in New Product Development Projects

This article investigates the effects of and interactions among the three prototypical control mechanisms of outcome control, process control, and clan control. Outcome control refers to the specification and evaluation of desired outputs that employees should deliver. Process control concerns mechanisms that specify which behaviors are appropriate, and clan control relies on socialization processes among organizational members. The authors argue that, whereas previous research has generally treated the control mechanisms in isolation, the different control mechanisms are interdependent and act as complements or substitutes in their influence on process performance, product concept effectiveness, and financial performance. The authors collected data through an online survey on 148 new product development projects conducted by high-tech companies located in the Netherlands. The results show that the combination of different controls may lead to synergistic or conflicting effects for the different new product development project outcomes. Outcome controls and clan controls synergistically increase process performance. This implies that the benefit of increasing goal clarity and project team autonomy through outcome controls can be strengthened by supporting it with social cohesion. In contrast, process controls hamper the effectiveness of clan controls in their positive effect on process performance. Potentially, the combination of these relatively information-intensive controls leads to a redundancy in communication that decreases process efficiency. In contrast to expectations, outcome and clan control only independently affect product concept effectiveness. Finally, the results show that outcome control and process control negatively interact in their impact on financial performance. This suggests that the installation of highly strict control systems that combine high levels of both outcome and process controls may lead to lower financial performance. The authors conclude that neglecting the interdependencies between different controls may lead to an incomplete insight into how firms can most effectively manage their new product development processes.
Accurate Analysis of Photonic Crystal Fibers by Means of the Fast-Fourier-Based Mode Solver

The recently proposed full-vectorial fast-Fourier-transform-based mode solver is applied to the rigorous analysis of arbitrarily shaped index-guiding photonic crystal fibers. The inclusion of perfectly matched layers absorbing boundary conditions into the formulation makes it possible to obtain an accurate description of the fundamental characteristics of these devices such as chromatic dispersion, modal birefringence, and confinement losses. Obtained results are in close agreement with those previously published in bibliography using other full-vectorial numerical approaches such as the biorthonormal-basis method, the cluster multiple-scattering method, and the finite-element methods
Starry‐eyed: journal rankings and the future of logistics research

Purpose – This is a polemical paper challenging both the principle and practice of journal ranking. In recent years academics and their institutions have become obsessive about the star‐ratings of the journals in which they publish. In the UK this is partly attributed to quinquennial reviews of university research performance though preoccupation with journal ratings has become an international phenomenon. The purpose of this paper is to examine the arguments for and against these ratings and argue that, on balance, they are having a damaging effect on the development of logistics as an academic discipline.Design/methodology/approach – The arguments advanced in the paper are partly substantiated by references to the literature on the ranking of journals and development of scientific research. A comparison is made of the rating of logistics publications in different journal ranking systems. The views expressed in the paper are also based on informal discussions with numerous academics in logistics and othe.
DETECTION OF A NEARBY HALO DEBRIS STREAM IN THE WISE AND 2MASS SURVEYS

Combining the Wide-Field Infrared Survey Explorer All-Sky Release with the Two Micron All Sky Survey Point Source Catalog, we detect a nearby, moderately metal-poor stellar debris stream spanning 24° across the southern sky. The stream, which we designate Alpheus, is at an estimated distance of ∼1.9 kpc. Its position, orientation, width, estimated metallicity, and, to some extent, its distance, are in approximate agreement with what one might expect of the leading tidal tail of the southern globular cluster NGC 288.
Firewood cable extraction in the southern Mediterranean area of Italy

This research assesses the efficiency and the costs of different cable cranes used in harvesting, in the forests of the southern Mediterranean area of Italy. During the study process a total of 100 cycle times were recorded in order to obtain the average performance. The cable cranes were tested in six different sites. Machine costs make up an essential part of timber harvesting costs; it is necessary to analyze these costs in order to decide which methods or machine types to use. Costs have been calculated using a standard hourly method. The present investigation showed that the three cable cranes extracted inferior volumes of timber compared to their load potential; in fact, the average extracted volume was inferior compared to the load capacity of the carriage. Nevertheless, from the comparison between cost per m3 and the market price of firewood, sufficient margins of value for the producer emerged. The level of productivity analyzed on these different sites showed that unproductive time influenced the extraction costs of wood. In fact, when the three cable cranes were productive the extraction cost of 1 m3 of firewood varied from €20.89 to €27.84.
Impact of Corporate Retailing on Price Spread Of Cauliflower in Odisha

The research study was conducted to know the impact of corporate retail marketing on price spread and profit of cauliflower cultivators in Bhubaneswar, Khurdha district of Odisha. Data were collected through a well prepared questionnaire from farmers supplying cauliflower through corporate retail market channel and traditional market channel. Three market channels were found out in the study area. Those were channel I: producers-commission agent-wholesaler-retailer-consumer, channel II: producer-wholesaler-retailer-consumer and channel III: producer-corporate market collection centre -corporate retail market's city processing centre retail outlet- consumers. Marketing cost (Rs. 25162.86) was highest for channel I and lowest for channel III and it was Rs. 9390/ha.Producers supplying their produce to corporate retail market's collection centre i.e. channel III were getting highest profit (Rs 3.49/Kg) than other two market channel. In channel I, producer's share in consumer's rupee was 32.93 percent. In channel II producer's share in consumer rupee was 35.93 percent and in channel III producer's share in consumer rupee was highest and it was 51.66 percent. Net margins of intermediaries were highest in channel I (36.5 percent) and it was less in channel III (22.5 percent) indicating that marketing efficiency was highest for channel III.
Budget participation's influence on budget slack : the role of fairness perceptions, trust and goal commitment

This research uses structural equation modelling to investigate a comprehensive model of the relationships between budget participation, procedural fairness, distributive fairness, trust, goal commitment and managers’ propensity to create slack. To this end, data from 163 U.S. individual managers were used for the study. The results show that budget participation impacts both procedural fairness and distributive fairness which, in turn, affect trust. Also, both procedural fairness and trust are found to have a significant impact on budget goal commitment which, in turn, negatively influences managers’ propensity to create slack. Further analyses indicate that the direct relationship between budget participation and manager’s propensity to create slack was insignificant, which suggests that fairness and goal commitment mediate the relationship between budget participation and manager’s propensity to create slack. The applied implications of this study, especially in relation to individual reactions to being ‘laid-off’, are also discussed.
Relationships Among Goal Difficulty, Business Strategies, and Performance On A Complex Management Simulation Task

A complex, strategic management, computer simulation was used over a ten-week period to examine the effect of goal difficulty and use of business strategies on firm performance. Participants developed a limited number of competitive business strategies, similar to well-known strategies identified in strategic management research, to deal with task complexity. Both goals and strategies had significant effects on performance, but the effect of strategy was stronger than that of goals. In addition, goals affected strategies, and strategies moderated the goal-performance relationship.
How corporate social responsibility information influences stakeholders' intentions

The study shows how positive and negative information on corporate social and environmental responsibility influences purchase, employment, and investment intentions of various stakeholders. We manipulated the information on corporate social responsibility (CSR) activities of a hypothetical firm in a between-subjects experimental design. The design had two treatments. In the ‘positive CSR’ treatment, the company's social and environmental performance was described in a positive perspective (depicting a strong social performance), whereas in the ‘negative CSR’ treatment it was described in a negative perspective (depicting a weak social performance). In both treatments, information about other key characteristics of the focal company were kept constant. Respondents' intentions to purchase products from, seek employment with, and invest in the company were evaluated by multi-item scales. The results demonstrate that positive CSR information about a firm enhances consumers' intentions to purchase products from, potential employees' intentions to seek employment with, and potential investors' intentions to invest in the company. Theoretical and managerial implications of the findings are discussed. Copyright © 2010 John Wiley & Sons, Ltd and ERP Environment.
Patellar Tracking During Simulated Quadriceps Contraction

The current study compared patella tracking during simulated concentric and eccentric quadriceps contractions in 12 knees from cadavers using a three-dimensional electromagnetic tracking system. The patella shifted (translated) and tilted medially during approximately the initial 22° tibiofemoral flexion. The patella then shifted and tilted laterally for the remaining arc of tibiofemoral flexion (90°). At 90° tibiofemoral flexion, the patella had an orientation of lateral patella shift and lateral patella tilt. Patella shift was significantly more lateral between 40° and 70° tibiofemoral flexion during concentric quadriceps action than during eccentric contraction. Patella tilt was significantly more lateral between 45° and 55° tibiofemoral flexion during concentric quadriceps contraction than during eccentric action. No other significant differences were seen between the quadriceps contraction conditions. The current study supports the hypothesis that patellar instability is most likely a result of various anatomic and physiologic factors causing a failure of the extensor mechanism to deliver the patella into the femoral sulcus and that a patellar dislocation rarely would occur in a normal knee.
An Equilibrium Model of Online Shopping Supply Chain Networks with Service Capacity Investment

In this paper we propose an online shopping supply chain network model that includes manufacturers, e-tailers, express service providers, and consumers. Consumers purchase products from e-tailers that can be either delivered by the express service companies or picked up by the customers themselves at certain physical locations, depending on the consumers' preferences on time and cost. In addition, the express service companies can make investments to improve their service quality. We identify the network structure of the problem, derive the equilibrium conditions, and establish the finite-dimensional variational inequality formulation. Theoretical results and numerical examples are presented to provide some managerial insights of the model.
Motivasi Petani dalam Berusahatani Hortikultura di Desa Wisata Candikuning, Kecamatan Baturiti, Kabupaten Tabanan

Abstract Farmers’ Motivation in Horticultural Farming in Candikuning Tourism Village, Baturiti Subdistrict, Tabanan Regency Horticultural farming in tourism destination is supposedly influenced by motivation who are able to encourage themselves who are not included in farmer community to carry out holticultural farming activities in the Candikuning Tourism Village. The purpose of this study is to determine the level of farmers’ motivation who are not included in farmer community in terms of intrinsic and extrinsic aspect in Horticultural Farming in Candikuning Tourism Village. The results show that the level of farmers’ motivation falls into high category with an average score of 3.67 (73.44%) of the total maximum score. This is supported by the intrinsic motivation included in the high category with an average score of 3.91 (78.34%) of the total maximum score and extrinsic motivation included in the high category with an average score of 3.42 (68.53%) of the total maximum score. So that the level of farmers’ motivation in horticultural farming is high. The agricultural extension workers that assist the farming activity in Candikuning Village should counsel the farmers actively. The farmers should form a farmer’s forum in order to facilitate them to gain information about their farming activity. The agricultural extension workers should be able to give effect to the farmers, through the delivery of messages that agricultural traders Keywords: motivation, farmers, horticultural farming, Candikuning Tourism Village
Transitional Care for Patients With Congestive Heart Failure: A Systematic Review and Meta-Analysis

PURPOSE We aimed to determine the impact of transitional care interventions (TCIs) on acute health service use by patients with congestive heart failure in primary care and to identify the most effective TCIs and their optimal duration. METHODS We conducted a systematic review and meta-analysis of randomized controlled trials, searching the Medline, PsycInfo, EMBASE, and Cochrane Library databases. We performed a meta-analysis to assess the impact of TCI on all-cause hospital readmissions and emergency department (ED) visits. We developed a taxonomy of TCIs based on intensity and assessed the methodologic quality of the trials. We calculated the relative risk (RR) and a 95% confidence interval for each outcome. We conducted a stratified analysis to identify the most effective TCIs and their optimal duration. RESULTS We identified 41 randomized controlled trials. TCIs significantly reduced risks of readmission and ED visits by 8% and 29%, respectively (relative risk = 0.92; 95% CI, 0.87–0.98; P = .006 and relative risk = 0.71; 95% CI, 0.51–0.98; P = .04). High-intensity TCIs (combining home visits with telephone followup, clinic visits, or both) reduced readmission risk regardless of the duration of follow-up. Moderate-intensity TCIs were efficacious if implemented for a longer duration (at least 6 months). In contrast, low-intensity TCIs, entailing only followup in outpatient clinics or telephone follow-up, were not efficacious. CONCLUSIONS Clinicians and managers who implement TCIs in primary care can incorporate these results with their own health care context to determine the optimal balance between intensity and duration of TCIs. High-intensity interventions seem to be the best option. Moderate-intensity interventions implemented for 6 months or longer may be another option.