Miracle-dz/UniFAR-FTUs huggingface dataset:
Relationship Between 2 Standardized Tackling Proficiency Tests and Rugby League Match-Play Tackle Performance.

This study investigated the relationship between 2 different assessments of tackling ability, physical qualities, and match-play performance in semiprofessional rugby league players. A total of 18 semiprofessional rugby league players (mean [SD]: age = 23.1 [2.0] y and body mass = 98.8 [11.8] kg) underwent tests of upper- and lower-body strength and power. Tackling ability was assessed using video analysis of under- and over-the-ball tackle drills. A total of 2360 tackles were analyzed from match play. Over-the-ball tackle ability was positively related to the proportion of dominant tackles (Spearman rank-order correlation coefficients [rs] = .52; 95% confidence interval [CI] .07-.79, P = .03) and average play-the-ball speeds (rs = .50; 95% CI .04-.78, P = .03) and negatively related to tackles that conceded offloads (rs = -.55; 95% CI -.78 to .04, P = .04). Under-the-ball tackle ability was significantly related to the proportion of dominant tackles (rs = .57; 95% CI .14-.82, P = .01) and missed tackles (rs = -.48; 95% CI -.77 to .02, P = .05). Good over-the-ball tacklers performed proportionally more dominant tackles, allowed significantly fewer offloads, and had longer average play-the-ball speeds. Good under-the-ball tacklers missed proportionately fewer tackles. This study suggests that both the under-the-ball and over-the-ball standardized tackle assessments are associated with varying indicators of match-play tackle performance and justifies the practical utility of these tests to assess and develop both types of tackles.
Current Mood Symptoms Do Not Affect the Accuracy of Retrospective Self-Ratings of Childhood ADHD Symptoms

Objective: Given that the diagnosis of adulthood ADHD depends on the retrospective self-report of childhood ADHD symptoms, this study aimed to establish whether current mood affects the accuracy of retrospective self-ratings of childhood ADHD. Method: Barkley’s Adult ADHD Rating Scale (BAARS) was used to assess the retrospective self- and parent-reports of childhood ADHD symptoms of 160 adults with ADHD and 92 adults without ADHD. Self-rated current mood was also measured using the Hospital Anxiety and Depression Scale (HADS). Results: Higher BAARS self-ratings correlated with higher HADS self-ratings. Strongest correlations were evident between hyperactive/impulsive symptoms and anxiety symptoms. There was no relationship between current mood and accuracy of self-report. Conclusion: Current mood does not affect the accuracy of retrospective self-ratings of ADHD. Future research should aim to provide new measures of anxiety in ADHD to avoid the double counting of hyperactive/impulsive and anxiety symptoms.
Pemphigus foliaceus, myasthenia gravis, thymoma and red cell aplasia

A 68‐year‐old man developed pemphigus foliaceus, myasthenia gravis with a spindle cell thymoma, and later died with red cell aplasia. At autopsy, pemphigus affected the oesophageal mucosa, and this finding was confirmed by direct immunofluorescence.
Effects of the Cu Doping on Critical Behavior of ${\rm La}_{0.7}{\rm Ca}_{0.3}{\rm MnO}_{3}$

We have studied the influence of the Cu-doping on the critical properties of a polycrystalline sample of La<sub>0.7</sub>Ca<sub>0.3</sub>Mn<sub>0.95</sub>Cu<sub>0.05</sub>O<sub>3</sub> prepared by solid-state reaction. Analyses of static magnetization data in the vicinity of the ferromagnetic-paramagnetic phase transition based on the modified Arrott plot reveal critical parameters of T<sub>C</sub> ≈ 197.3 K, β = 0.49 ± 0.03 and γ = 1.04 ± 0.04. These parameters are in good agreement with a magnetic equation of state M(H, ε) = ε<sup>β</sup>f±(H/ε<sup>β+γ</sup>), where ε = (T - T<sub>C</sub>)/T<sub>C</sub> (the reduced temperature), f<sub>+</sub> for T >; T<sub>C</sub> and f_ for T <; T<sub>C</sub>. Comparing with theoretical models, the critical exponents in our case are close to those expected for the mean-field theory. This reflects that the Cu doping leads to the second-order phase transition in La<sub>0.7</sub>Ca<sub>0.3</sub>Mn<sub>0.95</sub>Cu<sub>0.05</sub>O<sub>3</sub> while the parent compound of La<sub>0.7</sub>Ca<sub>0.3</sub>MnO exhibits the first-order phase transition. Such the phenomenon is assigned to changes in structural parameters, Mn<sup>3+</sup>/Mn<sup>4+</sup> ratio, and magnetic interaction mechanisms caused by Cu dopants.
The DinG Protein from Escherichia coli Is a Structure-specific Helicase*

The Escherichia coli DinG protein is a DNA damage-inducible member of the helicase superfamily 2. Using a panel of synthetic substrates, we have systematically investigated structural requirements for DNA unwinding by DinG. We have found that the helicase does not unwind blunt-ended DNAs or substrates with 3′-ss tails. On the other hand, the 5′-ss tails of 11-15 nucleotides are sufficient to initiate DNA duplex unwinding; bifurcated substrates further facilitate helicase activity. DinG is active on 5′-flap structures; however, it is unable to unwind 3′-flaps. Similarly to the homologous Saccharomyces cerevisiae Rad3 helicase, DinG unwinds DNA·RNA duplexes. DinG is active on synthetic D-loops and R-loops. The ability of the enzyme to unwind D-loops formed on superhelical plasmid DNA by the E. coli recombinase RecA suggests that D-loops may be natural substrates for DinG. Although the availability of 5′-ssDNA tails is a strict requirement for duplex unwinding by DinG, the unwinding of D-loops can be initiated on substrates without any ss tails. Since DinG is DNA damage-inducible and is active on D-loops and forked structures, which mimic intermediates of homologous recombination and replication, we conclude that this helicase may be involved in recombinational DNA repair and the resumption of replication after DNA damage.
Non-linearity in the determinants of capital structure: evidence from UK firms

We demonstrate that, by exploiting more fully the distribution of leverage, conditional quantile regression methods yield new insights into the choice of leverage ratio. For UK listed companies we find that not only is the estimated effect of the explanatory variables different at different quantiles of the distribution, but also that the effect of a variable changes sign between low leveraged and high leveraged firms.
Keyword extraction based on statistical information for cyrillic Mongolian script

We present a keyword extraction system for Mongolian documents using word co-occurrence statistical information which used in for English, Chinese and other languages. This method based on extracting top frequent words and building the co-occurrence matrix showing the occurrence of each frequent word. The biasness degree of the words and the set of frequent words are measured using CHI-Square Method (χ2). Also, the weight of the words and the set of frequent words are measured using word frequency — inverted word frequency (WF-IWF). Therefore words with high χ2 values and high WF-IWF values are likely to be keywords. The adopted χ2 method in this study is compared with another one method based on WF-IWF which tested for Mongolian. Two different documents were used to evaluate the system performance. We evaluate the effectiveness of χ2 method and WF-IWF method. Results show that the χ2 method is better than WF-IWF.
Forecasting the growth of multicell tumour spheroids: implications for the dynamic growth of solid tumours

The growth dynamics of multicell tumour spheroids (MTS) were analysed by means of mathematical techniques derived from signal processing theory. Volume vs. time trajectories of individual spheroids were fitted with the Gompertz growth equation and the residuals (i.e. experimental volume determinations minus calculated values by fitting) were analysed by fast fourier transform and power spectrum. Residuals were not randomly distributed around calculated growth trajectories demonstrating that the Gompertz model partially approximates the growth kinetics of three‐dimensional tumour cell aggregates. Power spectra decreased with increasing frequency following a 1/fδ power‐law. Our findings suggest the existence of a source of ‘internal’ variability driving the time‐evolution of MTS growth. Based on these observations, a new stochastic Gompertzian‐like mathematical model was developed which allowed us to forecast the growth of MTS. In this model, white noise is additively superimposed to the trend described by the Gompertz growth equation and integrated to mimic the observed intrinsic variability of MTS growth. A correlation was found between the intensity of the added noise and the particular upper limit of volume size reached by each spheroid within two MTS populations obtained with two different cell lines. The dynamic forces generating the growth variability of three‐dimensional tumour cell aggregates also determine the fate of spheroid growth with a strong predictive significance. These findings suggest a new approach to measure tumour growth potential.
Keratoglobus in Association With Posterior Polymorphous Dystrophy

Purpose: To report a case of a 34-year-old woman presenting with keratoglobus and posterior polymorphous corneal dystrophy (PPMD). Methods: Observational case report including ophthalmologic examination, topographic findings, and specular microscopy findings. Results: This patient presented with corneal steepening on topography consistent with keratoglobus, as well as large areas of irregular polymorphous changes of the corneal endothelium on specular microscopy consistent with PPMD. Conclusions: We report the first case with clinical features of both keratoglobus and PPMD. This report brings forth the description of keratoglobus findings on Orbscan topography.
Hernia Repair and Abdominoplasty in Gastric Bypass Patients

Background: Patients who sustain massive weight loss after open gastric bypass surgery are prone to incisional hernias. The authors undertook a retrospective study with two objectives: to characterize this patient population at their institution and to review their experience with treatment of incisional hernias in massive weight loss patients who had open gastric bypass surgery. With increasing prevalence of such patients, the authors aim to improve understanding and treatment of this disease entity and thereby improve patient outcomes. Methods: Operating room records and the patient database of the primary plastic surgeon treating massive weight loss patients at an academic teaching institution were retrospectively reviewed. Incisional hernia was often diagnosed before surgery but confirmed intraoperatively. Surgical management included primary repair of the hernia with plication of the abdominal wall from xiphoid to pubis and removal of redundant abdominal skin. Results: From February of 2001 to December of 2003, 40 patients had hernia repair in combination with abdominoplasty. Average age was 42 years, and average weight loss was 152 pounds. Average body mass index at the time of plastic surgery was 35.6. Average abdominal skin resection was 9.9 pounds. Hernia recurred in one patient with a body mass index of 41.3 after heavy lifting within 1 year of hernia repair surgery. Other complications included wound-healing problems (20 percent); seroma (12.5 percent); bleeding requiring surgical take-back (2.5 percent); suture abscess requiring surgical removal of suture (7.5 percent); bleeding anastomotic ulcer requiring transfusion (2.5 percent); and fatal pulmonary embolus (2.5 percent). Of the group, 60 percent had uncomplicated healing. Conclusions: Hernias are safely and preferentially repaired at the time of removal of redundant abdominal panniculus after massive weight loss sustained from gastric bypass surgery. The authors present their approach to hernia repair and abdominoplasty in this patient group, with acceptable results.
The Course of Research into the Economic Consequences of German Works Councils

In her recent survey, Carola Frege concludes that economic analysis of the works council has reached a ‘dead end’. The present paper offers a very different assessment. The evolving economic literature is shown to follow three distinct phases, the last of which contains some of the most positive evaluations to date of works council impact on establishment performance. Although these estimates are exaggerated, and the effects of works councils are likely to be small on average, the new literature redirects our research focus towards factors producing swings around this average, including differences in works council types and their workplace environments.
How do visual status and age impact on driving performance as measured on a closed circuit driving track?

The aim of this study was to determine the effects of age and visual impairment on driving performance as measured on a closed circuit course. Sixty two subjects were tested, including young (<30 years) visual normals, old (>60 years) visual normals and old (>60 years) subjects with early visual impairment. All subjects had a binocular visual acuity of 6/12 or better and were legally eligible to drive in Australia. Driving performance was assessed for sign detection and recognition, driving reaction times, speed estimation, and driving time.
Cortical stimulation mapping and Wada results demonstrate a normal variant of right hemisphere language organization

Purpose: Exclusive right hemisphere language lateralization is rarely observed in the Wada angiography results of epilepsy surgery patients. Cortical stimulation mapping (CSM) is infrequently performed in such patients, as most undergo nondominant left hemisphere resections, which are presumed not to pose any risk to language. Early language reorganization is typically assumed in such individuals, taking left hemisphere epileptiform activity as confirmation of change resulting from a pathologic process. We present data from CSM and Wada studies demonstrating that right hemisphere language occurs in the absence of left hemisphere pathology, suggesting it can exist as a normal, but rare variant, in some individuals. Furthermore, these data confirm the Wada test findings of atypical dominance.
Knowledge and Perception of the Resource Room

The purpose of this study was to determine regular and special education students' knowledge and perception of the elementary school, special education resource room. A sample of 126 nonhandicapped students and 20 students with learning disabilities, grades 1 through 6, were individually interviewed. Results indicate few differences between LD and non-LD students regarding their knowledge and perception of the resource room and special education. There are, however, significant differences between primary and intermediate students, with intermediate students having more knowledge of who goes to the resource room and more understanding of special education concepts. Most non-LD students ranked the resource room as a desirable place to spend time, though primary students with learning disabilities perceived it less positively than intermediate special education students.
Strengths and weaknesses of deep learning models for face recognition against image degradations

Deep convolutional neural networks (CNNs) based approaches are the state-of-the-art in various computer vision tasks, including face recognition. Considerable research effort is currently being directed towards further improving deep CNNs by focusing on more powerful model architectures and better learning techniques. However, studies systematically exploring the strengths and weaknesses of existing deep models for face recognition are still relatively scarce in the literature. In this paper, we try to fill this gap and study the effects of different covariates on the verification performance of four recent deep CNN models using the Labeled Faces in the Wild (LFW) dataset. Specifically, we investigate the influence of covariates related to: image quality -- blur, JPEG compression, occlusion, noise, image brightness, contrast, missing pixels; and model characteristics -- CNN architecture, color information, descriptor computation; and analyze their impact on the face verification performance of AlexNet, VGG-Face, GoogLeNet, and SqueezeNet. Based on comprehensive and rigorous experimentation, we identify the strengths and weaknesses of the deep learning models, and present key areas for potential future research. Our results indicate that high levels of noise, blur, missing pixels, and brightness have a detrimental effect on the verification performance of all models, whereas the impact of contrast changes and compression artifacts is limited. It has been found that the descriptor computation strategy and color information does not have a significant influence on performance.
Characterization of animals with microchips entering animal shelters.

OBJECTIVE To characterize animals with microchips entering animal shelters and the process used to find owners. DESIGN Cross-sectional study. ANIMALS 7,704 microchipped animals entering 53 animal shelters between August 2007 and March 2008. PROCEDURES Data for animals with microchips were recorded by participating animal shelters and reported monthly. RESULTS Of 7,704 animals, strays accounted for slightly more than half (4,083 [53.0%]), with the remainder classified as owner-relinquished animals (3,225 [41.9%]) and other (396 [5.1%]). Of 3,425 stray animals for which animal shelters reported that the owner was found, a higher percentage of dog owners (2,191/2,956 [74.1%]) than cat owners (298/469 [63.5%]) was found. For 876 animals for which the owners could not be found, the main reasons were incorrect or disconnected telephone number (310 [35.4%]), owner did not return telephone calls or respond to a letter (213 [24.3%]), and animal was registered to another group (151 [17.2%]). Of 1,943 animals for which animal shelters contacted a microchip registry, 1,129 (58.1%) were registered in the database. Purebred neutered dogs whose owner information was in the shelter database registry or microchip registry had a higher likelihood that the owners would be found. CONCLUSIONS AND CLINICAL RELEVANCE The high rate for return of microchipped dogs and cats to their owners supported microchipping as a valuable permanent pet identification modality; however, issues related to registration undermined its overall potential. Bundling of microchip implantation and registration, point-of-implantation data registration, use of annual compliance and update reminders, and providing access to all registries are potential solutions.
A genetic study of infantile and juvenile myasthenia gravis

From the present study, and from reports in the literature, two forms of childhood myasthenia emerge. There is an early-onset form (with onset of symptoms under 2 years of age) where the illness is milder but more persistent, and where there is frequent occurrence of myasthenia in sibs. Such cases are likely to be inherited as an autosomal recessive, although it is possible that they represent the extreme edge of a multifactorial distribution of combined genetic and environmental aetiology. The second group (with onset of symptoms between the age of 2 and 20 years) clinically resembles adult myasthenia, which is associated with autoimmunity and an increased incidence of thyroid dysfunction. Some genetic contribution occurs in this form but it is less marked than with the early-onset cases and there is no recognizable pattern of inheritance. As secondary cases are even less common among the families of adult myasthenics, it is likely that individuals with most genetic predisposition to myasthenia tend to develop symptoms early, and that non-genetic factors are relatively more important for the development of myasthenia in adults.
Metformin during pregnancy reduces insulin, insulin resistance, insulin secretion, weight, testosterone and development of gestational diabetes: prospective longitudinal assessment of women with polycystic ovary syndrome from preconception throughout pregnancy.

BACKGROUND In a prospective observational study of 42 pregnancies in 39 Caucasian women (age 30 +/- 4 years) with polycystic ovary syndrome (PCOS), we examined effects of metformin on maternal insulin, insulin resistance (IR), insulin secretion (IS), weight gain, development of gestational diabetes (GD), testosterone and plasminogen activator inhibitor activity. We assessed the hypothesis that diet-metformin (MET) lessens the physiological gestational increase in IR and reduces gestational weight gain, thus reducing GD. METHODS Preconception, in an out-patient clinical research centre, MET 1.5 (eight pregnancies) to 2.55 g/day (34 pregnancies) was started. Women with body mass index <25 or >or=25 kg/m(2) were given a 2000 or 1500 calorie/day, high-protein (26% of calories), low-carbohydrate (44%) diet. Calorie restrictions were dropped after conception. RESULTS On MET, GD developed in three out of 42 pregnancies (7.1%). Median entry weight (94.5 kg) fell to 82.7 on MET at the last preconception visit (P = 0.0001), fell further to 81.6 during the first trimester, was 83.6 in the second trimester, and 89.1 kg in the third trimester. Median weight gain during pregnancy was 3.5 kg. The median percentage reduction in serum insulin was 40% on MET at the last preconception visit; insulin did not increase in the first or second trimesters (P > 0.05), and rose 10% in the third trimester. The median percentage reduction in HOMA IR was 46% on MET at the last preconception visit; IR did not increase (P > 0.05) in the first, second or third trimesters. HOMA insulin secretion fell 45% on MET at the last preconception visit, did not increase in the first trimester, rose 24% in the second trimester, and rose 109% in the third trimester. Testosterone fell 30% on MET at the last preconception visit (P = 0.01) and then rose 74, 61 and 95% during trimesters 1, 2 and 3; median testosterone during the third trimester did not differ from pre-treatment levels. CONCLUSIONS By reducing preconception weight, insulin, IR, insulin secretion and testosterone, and by maintaining these insulin-sensitizing effects throughout pregnancy, MET-diet reduces the likelihood of developing GD, and prevents androgen excess for the fetus.
Prospective Economic Evaluation of a Peer Support Intervention for Prevention of Postpartum Depression among High-Risk Women in Ontario, Canada

Abstract Objective A previous multisite, randomized, controlled trial of peer support compared with usual care for prevention of postpartum depression demonstrated a reduction in depression symptoms at 12 weeks postbirth. Our objective was to determine the cost-effectiveness of this intervention. Study Design Prospectively planned economic evaluation alongside the clinical trial to determine the cost per case of postpartum depression averted, using individual patient data (n = 610) and societal perspective. All costs were expressed in 2011 Canadian dollars. Results The mean cost per woman was $4,497 in the peer support group and $3,380 in the usual care group (difference of $1,117, p < 0.0001). There was a 95% probability that the program would cost less than $20,196 per case of postpartum depression averted. Conclusions Although this is a volunteer-based program, it results in a net cost to the health care system and society. However, this cost is within the range for other accepted interventions for this population.
The Value of Carcinoembryonic Antigen Measurement in Clinical Practice

Dans le cancer colorectal mais aussi dans d'autres localisations ou les taux sont toutefois moins eleves (glande mammaire, estomac, poumons, pancreas, œsophage, col uterin, ovaire, endometre, voies urinaires, thyroide)