Progress in Molecular Diagnosis and Treatment of Genetic Based Pediatric Malignancies

and key words. An abstract of not more than 250 words should begin on page 2. It should be a factual, not descriptive, statement of study objectives, methods, principal results, and conclusions. Use Index Medicus terms from medical subject headings where possible. For the purpose of coding and subject indexing provide up to six key words in alphabetical order immediately following the abstract. Text. The text should be organized into an introductory section, including the background and purpose of the study, and then into sections titled “Methods”, “Results” and “Discussion”. In certain circumstances the nature of the report does not lend itself to this format. Underline any words or phrases to be emphasized by italics. Acknowledgments. Grant support and individuals who were of direct help in the reported work should be acknowledged by a brief statement on a separate page immediately following the text. References. References must be typed double spaced and listed in consecutive alphabetical and numerical order. All references must be cited in the text or tables. Once a reference has been cited, all subsequent citation should be to the original number. Unpublished data and personal communications are not acceptable references. All references must be verified against the original documents. Abbreviations of journals must conform to those in the list of Journals indexed in Index Medicus. Journals. References to journal articles should include surnames and initials of author(s) (list all authors if fewer than seven; if seven or more, list only the first three, followed by et al.), year, full title of article, abbreviated journal name, volume, and inclusive pagination: Dresdale DT, Schults M, Michtom RJ (1991) Primary pulmonary hypertension. I. Clinical and hemodynamic study. Am J Med 11: 686–705 Books. References to a book should include surnames and initials of author(s), year, title of book, city, publisher and edition: Jones KL (1988) Smith’s recognizable patterns of human malformation, 4th edn. Saunders, Philadelphia Chapter in a book. References to a chapter in a book should include surnames and initials of authors), year, chapter title, editor(s), book title, publisher, city, volume (if applicable), section (if applicable), and inclusive pagination: Thurlbeck WM (1992) Respiratory system. In: Dimmick JE, Kalousek DK (eds) Developmental pathology of the embryo and fetus. Lippincott, Philadelphia, pp 437–449 Papers in conference proceedings or abstracts. These references should include surnames and initials of author(s), year, title, title of conference, city, publisher, and inclusive pagination. Kjaer I (1994) The prenatal axial skeleton as marker of normal and pathological development of the human central nervous system. In: Alfred Benzon Symposium: Brain Lesions in the New-born. Munksgaard, Copenhagen, 37: 124–138 Polendo R, Lowe GN, McDougall S, Hahn TJ (1994) Mechanism of prostaglandin regulation of proteoglycan synthesis in rat chondrocytic cells (abstract). J Bone Miner Res 9: S187 Tables. Each table should be typed double spaced on a separate sheet of paper, numbered consecutively with Arabic numbers, and contain a brief title at the top. All tables must be cited in the text. Figures. Legends for figures should be typed double spaced on a separate sheet and numbered consecutively with Arabic numbers corresponding to the figures. The figure legend should be as clear as possible and should fully describe the contents the figure. All figures must be cited in the text. Figures should be professionally drawn and photographed and submitted in triplicate as black and white, high quality glossy prints. Special attention should be paid to focus and contrast. Do not submit original artwork. Symbols, letters, arrows, and numbers must be of sufficient size and contrast to be clearly recognizable when the figure is reduced to publication size. Paste a label on the back of each figure, indicating its number, name of author, title of paper, and the desired orientation. The optimal size for a figure is 8.6 × 10 cm (3.4 × 4 inch). If appropriate and acceptable these will be available for retrieval by readers in the online electronic version of the journal. A limited number of illustrations in full color will be considered, but the author may be required to bear the costs of part or all of their reproduction. Artwork to accepted manuscripts will not be returned unless a written request accompanies the page proofs. Electronic submission of final accepted manuscripts. Please send an electronic version of your manuscript with the final, accepted, double spaced hard copy. It is the author’s responsibility to ensure that the disk and hard copy match. Disks may be prepared on a PC in any version of Word or WordPerfect. Do not use desktop publishing software. Keep the document as simple as possible and avoid complex formatting. Follow the instructions for references very carefully. If incorrectly styled, the value of the diskette submission will be reduced. Abbreviations, spelling and units. Standard abbreviations and units listed in the Council of Biology Editors Style Manual: A Guide for Authors, Editors and Publishers in the Biological Sciences (5th edn, Bethesda, Md, Council of Biology Editors, 1983) should be used. All quantitative measurements should be in conventional metric units, followed when appropriate by the SI unit in parentheses. Permissions. Copyrighted material from other sources must be accompanied by written permission from both the publisher and author for reproduction. Any personal communication used in the text must be accompanied by a letter agreeing to be quoted as written. Review and action. Manuscripts will be examined by the editorial staff and sent to two reviewers. Authors will be notified of the disposition of their manuscript within 60 days. Case reports. Limit abstract to 150 words, use no more than three tables or figures and limit references to 15. Additional illustrations may be submitted for online storage and retrieval. Letters to the editor. Letters to the editor intended for publication should not exceed 800 words in length. Up to three references and two illustrations may accompany the letter. Letters must include the name, departmental and institutional affiliation and complete mailing address of the author. The editorial board reserves the right to accept, reject, or excerpt letters without changing the views expressed by the author (s). Page Proofs and Offprints. All material accepted for publication is subjected to copyediting. Authors will receive page proofs of articules before publication and should answer all queries and carefully check all editorial changes at this point. Offprints may be ordered at cost price when the page proofs are returned. INSTRUCTIONS FOR AUTHORS Annals of Diagnostic Paediatric Pathology Official Journal of the Polish Paediatric Pathology Society and Section of Oncological Surgery of Polish Association of Paediatric Surgeons Volume 10 Number 1–2 Summer 2006