Miracle-dz/UniFAR-FTUs huggingface dataset:
Treatment and Postsurgery Functional Outcome of Spaghetti Wrist

Abstract Background The outcomes of treating severe wrist injuries are not well understood and despite their complexity and prevalence, particularly among young adults, spaghetti wrist is rarely investigated. The aim of this study is to evaluate the postsurgery, functional outcome of spaghetti wrist injuries. Material and Methods In this prospective cross-sectional study, 153 patients with spaghetti wrist injuries were followed up for approximately 20 months and were assessed regarding returning to work and postsurgical functional outcomes that included tendon functionality, opposition, intrinsic function, deformity, sensation, and grip strength. Results The mean age was 28.3 ± 5 years. The most common cause of injury was glass window panes and bottles. Moreover, the most commonly involved structures were the tendons of flexor digitorum superficialis 3, 4, and 5. During the follow-up, the tendon functionality in 120 (78%), opposition in 115 (75.1%), and intrinsic function in 62 (40.5%) were “excellent. ” Hand sensation was “fair” in 75 patients (49.1%), “good” in 46 patients (30%), and “excellent” in 28 patients (18.3%). The average return time to activities of daily living was 10 months. Conclusion In this study, worse outcomes were seen in older patients and those with higher number of damaged structures (especially nerves).
Psychosocial Aspects of Pediatric Oncology

List of Contributors.Foreword (Jimmie Holland, MD, Head of Psychiatric Service, Memorial Sloan-Kettering NY, USA). PART ONE: MEDICAL ASPRCTS.1. Cancer in Children - An Introduction (Shai Izraeli and Gideon Rechavi). 2. Neuropsychological Aspects of Medical Treatments in Children with Cancer (Raymond Mulhern, et al.). 3. Palliative Care for Children with Advanced Cancer (Joanne Wolfe, et al.). 4. Pain in Children with Cancer (Richard D. W. Hain). 5. Care of a Child Dying of Cancer (Sergey Postovsky and Myriam Weyl Ben Arush). PART TWO: PSYCHOSOCIAL ASPECTS.6. The Child's Subjective Experience of Cancer and the Relationship with Parents and Caregivers (Daniel Oppenheim). 7. Quality of Life in Children with Cancer: Definition, Assessment and Results (Shulamith Kreitler and M ichal M. Kreitler). 8. Psychiatric Impact of Childhood Cancer (Margaret L. Stuber and Debra Seacord). 9. The Family of the Child with Cancer (Dafna Meitar). 10. Psychosocial Effects of Hematopoietic Cell Transplantation in Children (Ronit Elhasid, et al.). 11. The Survivors of Childhood Cancer (Amita Mahajan and Meriel E. M. Jenney). PART THREE: PSYCHOSOCIAL INTERVENTIONS.12. Speaking to Children about Serious Matters (Jane E. Skeen and M. Louise Webster). 13. Psychosocial Interventions: the Cognitive-Behavioral Approach (Bob F. Last and Martha A. Grootenhuis). 14. Complementary and Alternative Medicine Use in Children with Cancer (Cynthia D. Myers, et al.). 15. Fantasy, Art Therapies, Humor and Pets as Psychosocial Means of Intervention (Shulamith Kreitler, et al.). 16. Psychological Intervention with the Dying Child (Shulamith Kreitler & Elena Krivoi). 17. Education of the Sick Child: Learning and Reintegration into the School (Ciporah S. Tadmor and Myriam Weyl Ben Arush). Index.
Mosaicism in the skin: the importance of mild or minimal skin lesions.

O WING TO ITS ACCESSIBILITY, THE SKIN OFfers unique opportunities to observe and study the phenomenon of mosaicism. This seems to be more frequent than we used to believe. However, one must be aware of it to “see” it. The term mosaicism refers to the presence in an individual of 2 (or more) genetically distinct cell populations derived from the same zygote. In the 1980s, excellent clinicians provided clinical observations on mosaic patterns in the skin. It was Rudolf Happle, MD, who postulated new genetic concepts on mosaicism in skin, long before molecular genetic evidence was available. He also delineated the X-dominant chondrodysplasia punctata, known also as ConradiHünermann-Happle syndrome (CDPX2 [OMIM 302960]) and predicted the significance of Blaschko lines. In the years 1977 to 1981, the main characteristics of CDPX2 were described: the X-linked dominant inheritance pattern and the multiple organ involvement associating linear ichthyosis following the lines of Blaschko, chondrodysplasia punctata, cataracts, and short stature. The interpretation of the asymmetry of skeletal abnormalities, cataracts, and linear skin lesions, as consequences of functional mosaicism resulting from X-inactivation, was also a remarkable achievement.
Different types of well-being? A cross-cultural examination of hedonic and eudaimonic well-being.

A large international sample was used to test whether hedonia (the experience of positive emotional states and satisfaction of desires) and eudaimonia (the presence of meaning and development of one's potentials) represent 1 overarching well-being construct or 2 related dimensions. A latent correlation of . 96 presents negligible evidence for the discriminant validity between Diener's (1984) subjective well-being model of hedonia and Ryff's (1989) psychological well-being model of eudaimonia. When compared with known correlates of well-being (e.g., curiosity, gratitude), eudaimonia and hedonia showed very similar relationships, save goal-directed will and ways (i.e., hope), a meaning orientation to happiness, and grit. Identical analyses in subsamples of 7 geographical world regions revealed similar results around the globe. A single overarching construct more accurately reflects hedonia and eudaimonia when measured as self-reported subjective and psychological well-being. Nevertheless, measures of eudaimonia may contain aspects of meaningful goal-directedness unique from hedonia. (PsycINFO Database Record
Manual of small animal anesthesia

Preanesthetic Physical Examination and Evaluation. Preanesthetic Agents. Anesthetic Agents. Neuromuscular Blocking Agents. Anesthetic Equipment. Controlled Ventilation and Mechanical Ventilators. Perioperative Monitoring. Anesthetic Emergencies and Complications. Postanesthetic Care and Complications. Analgesia and Pain Management. Fluid, Electrolyte, And Acid-Base Balance: Maintenance in the Perioperative Period. Anesthetics Considerations in Patients with Preexisting Problems or Conditions. Anesthesia for Small to Medium Sized Exotic Mammals, Bird, And Reptiles. Index.
Enteral nutrition: our experience with percutaneous endoscopic gastrostomy (PEG) and revision of literature

Enteral nutrition (EN), as parenteral nutrition (PN), can be used in cases of patients whose medical conditions prevent the intake of food by mouth; unlike PN, EN keeps the functionality of the digestive tract and it makes home management of patients easier. However, the experience and literature have documented a number of serious complications, fortunately rare, which depend on the methods used in EN realization.We report in this paper our experience in 44 cases of percutaneous endoscopic gastrostomy (PEG), concluding that it is a safe and complications-free procedure. We believe that a nutritional intervention is indicated when, improving nutritional status, patients can obtain a better quality of life and have an average life expectancy. La nutrizione enterale: nostra esperienza con la gastrostomia percutanea per via endoscopica e revisione della letteratura Riassunto La nutrizione enterale, cosi come quella parenterale, e indicata in quei pazienti le cui condizioni cliniche generali non permettono l’assunzione di cibo per via orale, ma a differenza di quest’ultima preserva la funzionalita del tratto digestivo e rende piu facile la gestione domiciliare del paziente. Dalla letteratura e comunque noto che alcune particolari procedure di realizzazione della nutrizione enterale sono associate a complicanze anche severe, sebbene con una rara incidenza. In questo lavoro descriviamo la nostra esperienza nella realizzazione di 44 gastrostomie percutanee per via endoscopica, concludendo che la tecnica da noi utilizzata e sicura e priva di complicanze significative. Sulla base della nostra esperienza, e di una attenta revisione della letteratura, riteniamo che un intervento nutrizionale sia da consigliare nei pazienti con una aspettativa di vita media, qualora cio contribuisca ad un miglioramento significativo della qualita di vita.
Surgical Treatment of Childhood Inflammatory Myofibroblastic Tumors

Abstract Aim A retrospective study was performed to evaluate the clinical features, diagnostic methods, and treatment alternatives of childhood inflammatory myofibroblastic tumors (IMTs). Patients and Methods Patients who underwent surgical treatment for IMT between 2000 and 2015 were evaluated for age, sex, presenting symptoms, physical examination findings, diagnostic methods, treatment modalities, histopathologic findings, and results of surgical treatment during long-term follow-up. Results Eleven patients who underwent surgical treatment were included in the study. Male:female ratio was 7:4 and the mean age of the patients was 6.09 years (1–10 years). Presenting symptoms were respiratory difficulty, cough (n = 7, 63.3%), abdominal pain, vomiting (n = 2, 18.8%), loss of body weight (n = 1, 9.09%), palpable mass (n = 1, 9.09%), and rectal bleeding (n = 1, 9.09%). Ultrasonography (n = 4, 36.3%) and computed tomography (n = 9, 81.1%) were used for diagnosis. Localizations of tumors were lungs (n = 5, 45.4%), mediastinum (n = 2, 18.1%), spleen (n = 1, 9.09%), neck (n = 1, 9.09%), colon (n = 1, 9.09%), and rectum (n = 1, 9.09%). The mean size of mass was 6.6 cm (2–12 cm) and six patients were diagnosed with preoperative biopsy. Lung lobectomy (right lower lobe; n = 3, right middle and lower lobe; n = 2), total resection of mass with adjacent bowel (n = 2), partial splenectomy (n = 1), total resection of neck mass (n = 1), and incomplete resection (n = 2) were the choice of surgical treatment. Incomplete resection was performed in masses closely adjacent to atrium and mediastinal structures. In histopathologic evaluation, surgical margins were free of tumor in four cases, positive in six cases, and were not reported in one case. Anaplastic lymphoma kinase (ALK) positivity was detected in six cases, negative in two cases, and was not evaluated in three cases. Two cases who had residual mass with positive ALK received chemotherapy. Mean follow-up time was 68.2 months (5 months to 12 years). During follow-up, there was no recurrence or distant metastasis. Ten patients survived and one patient was lost to follow-up. Conclusion IMT is a rare tumor of childhood with a spectrum of clinical findings because of variable localization. Surgical treatment is the first choice of treatment. Patients with residual mass and ALK positivity may require medical treatment. In our series, long-term survival of patients was favorable in patients with total resection.
Unplanned admissions of older people : exploring the issues

1 Personal Social Services Research Unit, London School of Economics and Political Science 2 Faculty of Health, University of Plymouth 3 Centre for Research in Primary & Community Care, University of Hertfordshire 4 Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University 5 Personal Social Services Research Unit, University of Kent 6 School of Nursing and Midwifery, Clinical Education Centre, Keele University
Subclinical lower airways correlates of chronic allergic and non‐allergic rhinitis

The upper and lower airways behave as a physiological and pathophysiological unit. Subclinical lower airways abnormalities have been described in patients with rhinitis without asthma. These are expressed as bronchial hyperreactivity, abnormalities in lung function and bronchial inflammation, likely as a result of the same phenomenon with systemic inflammatory impact that reaches both the nose and the lungs, which for unknown reasons does not always have a full clinical expression. Patients with rhinitis are at increased risk of developing asthma; therefore, most authors suggest a careful clinical evaluation and monitoring of these patients, especially if symptoms related to inflammation in the lower airways are observed. Although current treatments, such as H1‐antihistamines, intranasal steroids and allergen immunotherapy, are quite effective for the management of rhinitis, it is difficult to prove their capacity to prevent asthma among subjects with rhinitis. Evidence showing that the treatment of rhinitis has a favourable impact on indicators of bronchial hyperreactivity and inflammation among subjects that have no symptoms of asthma is more frequently described. In this review, we address the frequency and characteristics of lower airway abnormalities in subjects with rhinitis, both in paediatric and adult populations, their likely predictive value for the development of asthma and the possibilities for therapeutic intervention that could modify the risk of subjects with rhinitis towards presenting asthma.
Pre-clinical validation of bone tissue engineering using mesenchymal stromal cells

The incidence of bone and joint related disorders such as osteoporosis, arthritis, as well as other diseases such as obesity, diabetes, and cancer, which can cause injury to orthopedic tissues and affect the health and capability of the human skeleton is on the rise. In such situations, the body’s own regenerative capacities are often exceeded resulting in poor healing of bony defects. Such situations necessitate the use of grafting material to aid the body in its restorative attempts. It has been estimated that globally, one million bone-grafting procedures are performed annually on the pelvis, spine, and other body extremities. 11% of these procedures rely on the use of synthetic bone graft substitutes. According to market analysis this number is expected to rise even further in the coming years due to the aging population, lifestyle issues, risks associated with obtaining autograft bone, the need to achieve superior and optimum bone fusion, speedy patient recovery and the need to eliminate multiple surgeries (in case of bone harvesting from the patient). The challenge is to provide these synthetic substitutes with osteoconductive and osteoinductive properties comparable to autologous bone. While altering the physical and chemical properties of the synthetic graft materials has been partially successful in endowing them with the desirable osteoinductive and conductive properties, till date their performance within the human body is not comparable to that of autologous bone. Adding growth factors such as bone morphogenetic proteins (BMPs) and stem cells have been proposed as alternative strategies to boost the biological properties of these materials. In this thesis, we have mainly focused on optimizing the combination of ceramic materials with stem cells derived from the adult bone marrow (BM derived MSCs) to engineer a bone graft which has potential to be used clinically as a replacement for autografts.
Obesity Bias Among Dietitians by Using the Fat People‐Thin People Implicit Association Test

The purpose of this project was to determine whether registered dietitians (RDs) exhibit a negative bias toward obese persons. The participants (n = 175) comprised a convenience sample of RDs from professional listservs, resulting in 128 (73%) completed surveys. The researchers used the Fat People-Thin People Implicit Association Test, found on the Web site: www.implicit. harvard.edu (designed to measure social knowledge). Bivariate associations were tabulated and an F test was performed to find association among variables. Across all categories, RDs (n = 98; 76%) had a strong to moderate preference (P = .05) for thin people in comparison with fat people, which exceeded the Implicit Associations Test results taken from the general population (n = 2.5 million; 52%). Registered dietitians tended to be less tolerant of obesity than those among the general population. Education for RDs on improving tolerance with individuals who are obese is recommended, especially for RDs who counsel overweight patients.
Therapeutic use of Immunomodulators in Endometritic cows and their effect on WBC and RBC indices

Forty crossbred cows with endometritis in estrus were divided into four groups each comprised of ten animals treated with single intrauterine (IU) infusion of E. coli lipopolysaccharide (LPS), single dose of Oyster Glycogen (OG) IU, 50 ml Autologus Plasma (AP) IU daily for three days and single infusion dose of Phosphate Buffer Solution (PBS) as control. Haematological estimation (WBC and RBC indices) was done before treatment and at post treatment subsequent estrus. A state of leucocytosis, neutrophilia and anaemia was prevailed pre-treatment evaluation. At post-treatment, subsequent estrus all the parameters returned significantly (P<0.01) towards normal in all the treatment groups except control. The recovery rate assessed was 100%, 80%, 60% and 20% respectively in four groups which coincided with corresponding post-treatment WBC and RBC indices. Hence, inference could be drawn that E. Coli LPS, OG and AP can effectively be used as alternative to antibiotics without any adverse effect on haemopoietic system.
Unilateral milia‐type intradermal tophi associated with underlying urate subcutaneous deposition: an uncommon cutaneous presentation of gout

Tophi develop during the most advanced clinical stage of gout, and are usually located on or around the joints. However, unusual skin features caused by intradermal and/or subcutaneous deposition of tophaceous material at locations other than articular regions have been reported. We present the case of a patient with a condition that has been recently termed ‘miliarial gout’. which is only the second such case, to our knowledge. A 51‐year‐old woman, who had a chronic joint disease that had been diagnosed and treated as psoriatic arthritis, presented with multiple asymptomatic, yellowish‐white, firm papules (1–3 mm in size) on erythematous areas on the outside of her left leg. On histological examination of a skin biopsy, uric acid crystals were seen in the dermis and subcutis. The patient also had a raised level of serum urate, consistent with a diagnosis of gout. Treatment with allopurinol led to rapid improvement. Intake of corticosteroids and diuretics was a possible triggering factor for the development of cutaneous tophi in this patient.
Parenting and psychiatric rehabilitation: can parents with severe mental illness benefit from a new approach?

OBJECTIVE The aim of this pilot implementation study was to explore the initial experiences with and impact of Parenting with Success and Satisfaction (PARSS), a psychiatric rehabilitation and recovery-based, guided self-help intervention, for parents with severe mental illnesses. METHODS Changes in the PARSS intervention group were compared with changes in a control group in a nonequivalent control group design. Outcome measures included: parenting satisfaction reported by parents; parenting success reported by mental health practitioners and family members; empowerment as reported by parents, practitioners and family members; and parents' reported quality of life. Additional process data were obtained on relationship with practitioner, quality of contact, satisfaction with the intervention and fidelity. RESULTS Parenting satisfaction increased after 1 year for the PARSS group, but not for the control group. Parents' reports of empowerment did not change for either group. The scores of parents' empowerment reported by practitioners and family members increased in the control group, with no such change in the PARSS group. Quality of life improved significantly for the intervention group. Process measures showed that, although PARSS was not always implemented as intended, both parents and practitioners expressed satisfaction with the intervention. CONCLUSIONS AND IMPLICATIONS FOR PRACTICE The first experiences with PARSS were mixed. This intervention, implemented by mental health practitioners, has the potential to function as a useful tool for supporting parents. Attention must be paid to enhancing intervention implementation and fidelity.
Analysis of Explosives by Negative Ion Chemical Ionization Mass Spectrometry

Negative ion chemical ionization (NCI) mass spectrometry using isobutane as a reagent has been applied to the analysis of explosives. The method is evaluated as complementary to positive ion CI, as both methods can be applied to the same sample. We used a magneticsector-type mass spectrometer without changing the electron multiplier voltage. Under these conditions NCI mass spectra of explosives have been obtained at a sensitivity similar to that of positive ion CI mass spectra.
Relating Chronic Pelvic Pain and Endometriosis to Signs of Sensitization and Myofascial Pain and Dysfunction

Abstract Chronic pelvic pain is a frustrating symptom for patients with endometriosis and is frequently refractory to hormonal and surgical management. While these therapies target ectopic endometrial lesions, they do not directly address pain due to central sensitization of the nervous system and myofascial dysfunction, which can continue to generate pain from myofascial trigger points even after traditional treatments are optimized. This article provides a background for understanding how endometriosis facilitates remodeling of neural networks, contributing to sensitization and generation of myofascial trigger points. A framework for evaluating such sensitization and myofascial trigger points in a clinical setting is presented. Treatments that specifically address myofascial pain secondary to spontaneously painful myofascial trigger points and their putative mechanisms of action are also reviewed, including physical therapy, dry needling, anesthetic injections, and botulinum toxin injections.
Abdominal Organ Involvement in Blunt Injuries

Visceral injuries of the abdomen following blunt trauma present a great medico-legal problem to the forensic experts. Thus the doctor should remain alert to the development of signs and symptom after blunt trauma to the abdomen in vehicular accident otherwise he may be charged of negligence. Among 55 fatal cases of blunt abdominal injury, maximum number of cases belongs to the age group 20–29 yrs. Males were the predominant victims with ratio 4:1. It was found that road traffic accidents by heavy vehicle like bus; car and truck were responsible for 70% of blunt abdominal injuries. Among 55 cases of blunt injury, the incidence of the involvement of liver, spleen, small intestine, kidney, stomach and urinary bladder were 67%, 30.91%, 18%, 10.9%, 9.09%, 5% cases respectively. Genitals were found injured in 3% cases of blunt injury abdomen. For Blunt Injuries of Abdomen majority of the cases i.e. 78.18% were of accidental, 18.18% were homicidal and 3.6% suicidal in nature. Immediate cause of death was shock and hemorrhage and in those cases where death was delayed, cause of death was septicemia.