Miracle-dz/UniFAR-FTUs huggingface dataset:
The Relationship between Professional Values and Clinical Decision Making among Nursing Student

Professional values provide internal motivation and improve ethical responsibility and professional devotion. Therefore, each professional is at the center of performance and decision-making. The study aimed to identify relationship between professional values and decision making among nursing students. Materials and Method: Descriptive – co-relational design was used. The study was conducted at Faculty of Nursing at Tanta University. Convenience sample (395) nursing students were selected from third and fourth academic year where third year (150) nursing student and fourth year (245) nursing student. The data was collected by using Nursing Professional Value Scale and Nurse Decision Making Instrument -Revised 2014. Results: More than fifty percent (59.3%) of nursing student had high level of professional values while 76.25% of nursing student had moderate level of clinical decision making. Nursing students' total clinical decision making was significantly correlated with their total professional values. Also; it was significantly correlated with all dimensions of professional values except professionalism dimension. Conclusion: It can be concluded that more than fifty percent of nursing student at Tanta Faculty of nursing had high level of professional values specifically, justice, trust, activism, professionalism, and caring respectively. While, more than seventy of them had moderate level of clinical decision making. Nursing students' total clinical decision making was significantly correlated with their total of professional values and its dimensions except professionalism dimension. Recommendations: Nursing educators could facilitate involvement of students by adding action situations as part of nursing curriculum. They must provide more opportunities of students that allow them to experience more situations similar to clinical settings in order to enhance learning clinical decision making and apply professional values.
Fear and Loathing in Boston: the Roles of Different Emotions in Information Sharing on Social Media following a Terror Attack

Emotions are essential to how we communicate, and online discussions are no exception. As most of the analysis on emotion so far has looked at polarity rather than specific emotions, we do not yet have a full understanding of how different emotions spark different behaviours. This study examines how five different emotions are associated with information sharing in the context of a terror attack both on a large scale and when including geolocation information in the analysis. Contrary to what previous findings suggest, increased fear and contempt levels have a negative relation with increased levels of retweeting. Positive emotion in tweets meant a decrease in retweet rates in the geolocation specific data, but an increase when all tweets were considered.
Genetic divergence analysis in bread wheat ( Triticum aestivum L . )

The study was conducted to assess the genetic diversity among 40 genotypes of bread wheat (Triticum aestivum L.). The genetic diversity analysis revealed the formation of 13 clusters suggesting the presence of wide genetic diversity. The clustering pattern indicated that geographic diversity was not associated with genetic diversity. The analysis of per cent contribution of various characters towards the expression of total genetic divergence indicated that grain yield per plant followed by length of main spike, number of effective tillers per plant, plant height, number of grains per main spike and grain filling period contributed maximum towards total genetic divergence. Based on the maximum genetic distance, it is advisable to attempt crossing of the genotypes from cluster XII with the genotypes of cluster X, which may lead to the generation of broad spectrum of favourable genetic variability for yield improvement in bread wheat.
Mol 2 Net Effect of Neuronal Nitric Oxide Synthase Inhibitors and Antioxidants on the Development of Tolerance by Different Opioid Agonists in the Rat Locus Coeruleus

Nitric oxide (NO) is involved in acute μ-opioid receptor (MOR) desensitization in the locus coeruleus (LC) and in the neuroadaptations following chronic morphine administration. However, the role of NO and NO-derived reactive oxygen species (ROS) in the development of cellular tolerance to different opioids remains unclear. Herein, we examined the effect of the selective neuronal nitric oxide synthase (nNOS) inhibitor 7-nitroindazole (7-NI; 30 mg/kg/12 h, i.p.) and the antioxidants Trolox + ascorbic acid (TX+AA; 40 and 100 mg/kg/day, respectively, i.p.) and U-74389G (10 mg/kg/day, i.p.) on the development of cellular tolerance induced by morphine, methadone and fentanyl. For induction of morphine tolerance, rats were treated subcutaneously with a slow release emulsion containing free base morphine (200 mg/kg, 3 days). For methadone (60 mg/kg/day, 6 days) and fentanyl (0.2 mg/kg/day, 7 days), tolerance was induced by s.c. implantation of osmotic pumps. Concentration-effect curves for the inhibitory effect of Met5-enkephalin (ME; 0.05-12.8 μM, 2x, 1 min) on the firing rate were performed by single-unit extracellular recordings of LC neurons from rat brain slices. Morphine, methadone and fentanyl treatments shifted to the right concentration-effect curves for ME and increased the EC50 by 2-4 folds. Co-administration of TX+AA or U-74389G in morphine-treated animals prevented the development of tolerance in LC neurons. Conversely, co-treatments with U74389G or 7-NI failed to affect the induction of cellular tolerance after methadone or fentanyl treatments. Our results suggest that MOR agonists with different intrinsic efficacies cause variable degrees of cellular tolerance in LC cells. Moreover, NO/ROS pathways are differentially involved in opioid tolerance after prolonged treatments with morphine, methadone and fentanyl.
NUMERICAL SIMULATION FOR THE SEISMIC BEHAVIOUR OF MID-RISE CLT SHEAR WALLS WITH COUPLING BEAMS

In this paper, an innovative type of mid-rise Cross Laminated Timber shear walls with coupling beams was designed. The 5-layer CLT panels were continuous along the height. Hold-downs and angle brackets were installed at the bottom of the panels. Coupling beams with energy dissipation devices were used to decrease the deformation and internal forces of the walls, providing adequate stiffness and strength. A numerical model was developed in OpenSees for a six storey prototype to investigate its seismic behaviour with different configurations. Strength degradation, stiffness degradation, and pinching effect were considered in the connection models. The structural performance was evaluated through a series of static and transient analyses. The simulation results indicated adequate lateral resistance and deformation capacity of this structural type. This study will lead to more application of large size CLT panels in multi-storey CLT buildings as lateral resistant systems.
Subacute stress and chronic stress interact to decrease intestinal barrier function in rats

Abstract Psychological stress increases intestinal permeability, potentially leading to low-grade inflammation and symptoms in functional gastrointestinal disorders. We assessed the effect of subacute, chronic and combined stress on intestinal barrier function and mast cell density. Male Wistar rats were allocated to four experimental groups (n = 8/group): 1/sham; 2/subacute stress (isolation and limited movement for 24 h); 3/chronic crowding stress for 14 days and 4/combined subacute and chronic stress. Jejunum and colon were collected to measure: transepithelial electrical resistance (TEER; a measure of epithelial barrier function); gene expression of tight junction molecules; mast cell density. Plasma corticosterone concentration was increased in all three stress conditions versus sham, with highest concentrations in the combined stress condition. TEER in the jejunum was decreased in all stress conditions, but was significantly lower in the combined stress condition than in the other groups. TEER in the jejunum correlated negatively with corticosterone concentration. Increased expression of claudin 1, 5 and 8, occludin and zonula occludens 1 mRNAs was detected after subacute stress in the jejunum. In contrast, colonic TEER was decreased only after combined stress, and the expression of tight junction molecules was unaltered. Increased mast cell density was observed in the chronic and combined stress condition in the colon only. In conclusion, our data show that chronic stress sensitizes the gastrointestinal tract to the effects of subacute stress on intestinal barrier function; different underlying cellular and molecular alterations are indicated in the small intestine versus the colon.
E ¢ cient Repeated Implementation II : Incomplete Information

This paper extends Lee and Sabourian [14] and examines repeated implementation of a social choice function in a general incomplete information environment where agents are in nitely-lived and their preferences are determined stochastically in each period. Our main result establishes how any e¢ cient social choice function can be repeatedly implemented in Bayesian Nash equilibrium. Neither incentive compatibility nor (Bayesian) monotonicity is necessary for repeated implementation. JEL Classi cation: A13, C72, C73, D78
Violent Video Games and Reciprocity

Numerous studies have shown that playing violent video games alone increases subsequent aggression. However, social game play is becoming more popular than solo game play, and research suggests cooperative game play is beneficial for players. The current studies explore the effects of cooperative game play on player’s subsequent aggressive behaviors toward video game partners (Experiment 1) and non-video game partners (Experiment 2), while providing a discussion of possible theories applicable to social video game play. Cooperative games resulted in less aggression between video game partners (Experiment 1) and between non-video game partners (Experiment 2) than did competitive or stand-alone games. Interestingly, cooperative game play and no-game play produced similar levels of aggression (Experiment 1), whereas competitive and solo game play produced similar levels of aggression (Experiment 2). These findings are consistent with the theory of bounded generalized reciprocity. Playing violent games cooperatively can offset the aggression-increasing effects of violent video games.
Evaluation of Cell Block Technique in the Cytodiagnosis of Body Fluids

Background: Conventional smear preparation is simple procedure but have many disadvantages causing the difficulties in making the definitive diagnosis however cell block are particularly useful when the cytological abnormalities are misleading. Once positive diagnosis is made it is often considered definitive diagnosis and it is paramount important to identify primary site and type of malignancy. This can help obviate the proper surgical management, chemotherapy and radiotherapy so as to increase patients’ survival rate. Aims: To study cell block preparation of all body fluids along with conventional cytology smear and to know primary site of malignant effusions and evaluating cell block technique in cytodiagnosis of same. Material and Methods : Present prospective study was conducted in tertiary care hospital which includes fresh body fluids minimum of 15 ml in two separate containers (from pleural and peritoneal cavity) from 142 patients with all relevant clinical details of both sexes and all ages.scanty fluid samples were excluded.Samples were processed by conventional smear method and cell block method. Results: 142 body fluid specimens were evaluated by simultaneous use of smear and cell block technique of which 80% were pleural effusions and 20%were peritoneal fluids,Male:Female was 2:1, most of the patients were in the age group of 41-60 years. In Conventional smear prepration showed diagnostic yield 15% and accuracy 85-90% . In Cell block technique showed increase in diagnostic yield upto 21% and accuracy upto 97%. Conclusion: CB in conjunction with CS increases the accuracy of the fluid reports. The CB method provides high cellularity, better architectural patterns and use of IHC help to indentify primary site of malignacy giving more definitive diagnosis .
Optimization of Clay Mould for Concrete Casting Using Design of Experiments

This paper presents a research work to optimize the Additive Manufactured (AM) clay moulds for concrete casting utilizing the Design of Experiments (DOE). The objective of this approach is to understand the impacts of clay moulds’ fabrication parameters on the displacement of cast concrete artefacts. This will contribute to efficient and economical clay mould production without losing accuracy. We adopt a DOE approach to reveal insights into the influence of critical fabrication parameters on the displacement of the final concrete artefact and thus, suggest critical parameter settings to ensure that the lateral pressure exerted by concrete in the vertical build-up is sustained. We demonstrate experimental results for a case study: vertical columns of circular cross-sections.
Self-enhancement Influences Medial Frontal Cortex Alpha Power to Social Rejection Feedback

Although previous research has demonstrated that individuals are motivated to self-enhance, the neurocognitive mechanisms and temporal dynamics of self-enhancement are poorly understood. The current research examined whether self-enhancing motivations affect the perceptual processing of social feedback. Participants who varied in self-enhancement motivations received accept and reject feedback while EEG was recorded. Following this task, we measured perceptions of feedback by asking participants to estimate the number of times they were rejected. Source localization and time–frequency analyses revealed that alpha power in the medial frontal cortex (MFC) completely mediated the relationship between self-enhancement motivations and rejection estimates. Specifically, greater self-enhancement motivations predicted decreased MFC alpha power to reject compared to accept feedback, which predicted decreased rejection estimates. These findings suggest that self-enhancement motivations decrease perception of social rejection by influencing how the MFC processes social feedback.
Competitive Models to Detect Stock Manipulation

In this paper, data from the Indian stock market is used to study the prediction accuracy of various classification techniques that can be used to identify market manipulation. The data contains information regarding price, volume and volatility of various stocks. Techniques like discriminant analysis, a composite model based on artificial neural network – genetic algorithm (ann-ga) and support vector machine (svm) have been used for classifying stocks into manipulated and non manipulated categories. It is observed that the support vector machine based technique gives the best classification accuracy among the three techniques.
Characterization of the AMPA‐Activated Receptors Present on Motoneurons

Abstract: Motoneurons have been shown to be particularly sensitive to Ca2+‐dependent glutamate excitotoxicity, mediated via AMPA receptors (AMPARs). To determine the molecular basis for this susceptibility we have used immunocytochemistry, RT‐PCR, and electrophysiology to profile AMPARs on embryonic day 14.5 rat motoneurons. Motoneurons show detectable AMPAR‐mediated calcium permeability in vitro and in vivo as determined by cobalt uptake and electrophysiology. Motoneurons express all four AMPAR subunit mRNAs, with glutamate receptor (GluR) 2 being the most abundant (63.9 ± 4.8%). GluR2 is present almost exclusively in the edited form, and electrophysiology confirms that most AMPARs present are calcium‐impermeant. However, the kainate current in motoneurons was blocked an average of 32.0% by Joro spider toxin, indicating that a subset of the AMPARs is Ca2+‐permeable. Therefore, heterogeneity of AMPARs, rather than the absence of GluR2 or the presence of unedited GluR2, explains AMPAR‐mediated Ca2+ permeability. The relative levels of flip/flop isoforms of each subunit were also examined by semiquantitative PCR. Both isoforms were present, but the relative proportion varied for each subunit, and the flip isoform predominated. Thus, our data show that despite high levels of edited GluR2 mRNA, some AMPARs are Ca2+‐permeable, and this subset of AMPARs can account for the AMPAR‐mediated Ca2+ inflow inferred from cobalt uptake and electrophysiology studies.
Integration of genomic and gene expression data of childhood ALL without known aberrations identifies subgroups with specific genetic hallmarks

Pediatric acute lymphoblastic leukemia (ALL) comprises genetically distinct subtypes. However, 25% of cases still lack defined genetic hallmarks. To identify genomic aberrancies in childhood ALL patients nonclassifiable by conventional methods, we performed a single nucleotide polymorphisms (SNP) array‐based genomic analysis of leukemic cells from 29 cases. The vast majority of cases analyzed (19/24, 79%) showed genomic abnormalities; at least one of them affected either genes involved in cell cycle regulation or in B‐cell development. The most relevant abnormalities were CDKN2A/9p21 deletions (7/24, 29%), ETV6 (TEL)/12p13 deletions (3/24, 12%), and intrachromosomal amplifications of chromosome 21 (iAMP21) (3/24, 12%). To identify variation in expression of genes directly or indirectly affected by recurrent genomic alterations, we integrated genomic and gene expression data generated by microarray analyses of the same samples. SMAD1 emerged as a down‐regulated gene in CDKN2A homozygous deleted cases compared with nondeleted. The JAG1 gene, encoding the Jagged 1 ligand of the Notch receptor, was among a list of differentially expressed (up‐regulated) genes in ETV6‐deleted cases. Our findings demonstrate that integration of genomic analysis and gene expression profiling can identify genetic lesions undetected by routine methods and potential novel pathways involved in B‐progenitor ALL pathogenesis. © 2008 Wiley‐Liss, Inc.
Autonomy and Competence in German and American University Students: A Comparative Study Based on Self-Determination Theory.

According to self-determination theory (R. M. Ryan & E. L. Deci, 2000), supports for autonomy and competence are essential for growth and well-being in any learning environment. Educational contexts differ in their relative support for these 2 needs. The authors examined the role of autonomy and competence in 2 German and 2 American university settings, as they were predicted to differ in terms of their relative emphasis on competence versus autonomy. Invariance analyses supported the construct comparability of the measures and demonstrated that German students felt significantly more autonomous and less competent than American students. Perceived pressures and positive informational feedback were modeled as antecedents of autonomy and competence, and well-being was examined as a consequence. The hypothesized model was generally supported across the 4 samples.
Different Intravenous Contrast Media Concentrations Do Not Affect Clinical Assessment of 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scans in an Intraindividual Comparison

ObjectiveThe purpose of this study was to perform an intraindividual comparison of the influences of different iodine contrast media on tracer uptake, contrast enhancement, and image quality in combined positron emission tomography (PET)/computed tomography (CT). Materials and MethodsFifty-one patients underwent baseline and follow-up combined PET/CT consisting of low-dose unenhanced and venous contrast-enhanced CT with contrast media containing a high concentration of iodine (iopromide, 370 mg/mL) and a standard iodine concentration (iopromide, 300 mg/mL). The total iodine load (44.4 g) and the iodine delivery rate (1.29 g/s) were identical for the 2 protocols. The mean and maximum standard uptake values, as measures of tracer uptake and contrast enhancement for unenhanced and contrast-enhanced PET/CT, were quantified at 10 different anatomical sites, and images were analyzed for clinically relevant differences. ResultsThe mean and maximum standard uptake values were significantly increased in contrast-enhanced PET/CT compared with unenhanced PET/CT at each anatomical site (P < 0.05). Comparison of tracer uptake between the 300- and 370-mg iodine contrast media showed no significant differences (all P > 0.05). Comparison of contrast enhancement between the 300- and 370-mg iodine contrast media showed no significant difference at any anatomical site (all P > 0.05). Analysis of image quality revealed no clinically relevant differences between the 2 different iodine contrast media (P = 0.739). ConclusionThe use of contrast-enhanced CT scans for attenuation correction in PET/CT does not cause clinically relevant artifacts in PET scan reconstruction, regardless of the iodine concentration used. Standard- and high-iodine contrast media can be used equivalently.
Efficient Stereo Matching Using Adaptive Manifolds

By providing the eyes of a observer with two different images of the same scene, stereoscopic 3D is widely used in stereoscopic video games, movies and virtual reality applications. In this paper, we present an efficient local stereo matching method using adaptive manifolds. There are two main steps in this algorithm. Firstly, we employ adaptive manifolds to implement the adaptive support window technique at the stage of cost aggregation. Secondly, adaptive manifolds are utilized to implement a weighted median filter to remove streak-like effects at the stage of post-processing. To evaluate the performance of our algorithm, we compare with many local stereo matching methods using the standard evaluation benchmark in the Middlebury website and the results show that the method can effectively fulfill the task of stereo matching for stereoscopic images.
Precise quantification of translation inhibition by mRNA structures that overlap with the ribosomal footprint in N-terminal coding sequences

A mRNA’s translation rate is controlled by several sequence determinants, including the presence of RNA structures within the N-terminal regions of its coding sequences. However, the physical rules that govern when such mRNA structures will inhibit translation remain unclear. Here, we introduced systematically designed RNA hairpins into the N-terminal coding region of a reporter protein with steadily increasing distances from the start codon, followed by characterization of their mRNA and expression levels in E. coli. We found that the mRNAs’; translation rates were repressed, by up to 1410-fold, when mRNA structures overlapped with the ribosome’s footprint. In contrast, when the mRNA structure was located outside the ribosome’s footprint, translation was repressed by less than 2-fold. By combining our measurements with biophysical modeling, we determined that the ribosomal footprint extends 13 nucleotides into the N-terminal coding region and, when a mRNA structure overlaps or partially overlaps with the ribosomal footprint, the free energy to unfold only the overlapping structure controlled the extent of translation repression. Overall, our results provide precise quantification of the rules governing translation initiation at N-terminal coding regions, improving the predictive design of post-transcriptional regulatory elements that regulate translation rate.