Miracle-dz/UniFAR-FTUs huggingface dataset:
DIFFUSE Lyα EMITTING HALOS: A GENERIC PROPERTY OF HIGH-REDSHIFT STAR-FORMING GALAXIES

Using a sample of 92 UV continuum-selected, spectroscopically identified galaxies with 〈z〉 = 2.65, all of which have been imaged in the Lyα line with extremely deep narrow-band imaging, we examine galaxy Lyα emission profiles to very faint surface brightness limits. The galaxy sample is representative of spectroscopic samples of Lyman break galaxies (LBGs) at similar redshifts in terms of apparent magnitude, UV luminosity, inferred extinction, and star formation rate and was assembled without regard to Lyα emission properties. Approximately 45% (55%) of the galaxy spectra have Lyα appearing in net absorption (emission), with ≃ 20% satisfying commonly used criteria for the identification of “Lyα emitters” (LAEs; W0(Lyα) ⩾ 20 Å). We use extremely deep stacks of rest-UV continuum and continuum-subtracted Lyα images to show that all sub-samples exhibit diffuse Lyα emission to radii of at least 10″ (∼80 physical kpc). The characteristic exponential scale lengths for Lyα line emission exceed that of the λ0 = 1220 Å UV continuum light by factors of ∼5–10. The surface brightness profiles of Lyα emission are strongly suppressed relative to the UV continuum light in the inner few kpc, by amounts that are tightly correlated with the galaxies’ observed spectral morphology; however, all galaxy sub-subsamples, including that of galaxies for which Lyα appears in net absorption in the spectra, exhibit qualitatively similar diffuse Lyα emission halos. Accounting for the extended Lyα emission halos, which generally would not be detected in the slit spectra of individual objects or with typical narrow-band Lyα imaging, increases the total Lyα flux (and rest equivalent width W0(Lyα)) by an average factor of ∼5, and by a much larger factor for the 80% of LBGs not classified as LAEs. We argue that most, if not all, of the observed Lyα emission in the diffuse halos originates in the galaxy H ii regions but is scattered in our direction by H i gas in the galaxy's circum-galactic medium. The overall intensity of Lyα halos, but not the surface brightness distribution, is strongly correlated with the emission observed in the central ∼1″—more luminous halos are observed for galaxies with stronger central Lyα emission. We show that whether or not a galaxy is classified as a giant “Lyα blob” (LAB) depends sensitively on the Lyα surface brightness threshold reached by an observation. Accounting for diffuse Lyα halos, all LBGs would be LABs if surveys were sensitive to 10 times lower Lyα surface brightness thresholds; similarly, essentially all LBGs would qualify as LAEs.
Regional atrophy of the corpus callosum in dementia

The regional distribution of degeneration of the corpus callosum (CC) in dementia is not yet clear. This study compared regional CC size in participants (n = 179) from the Cache County Memory and Aging Study. Participants represented a range of cognitive function: Alzheimer's disease (AD), vascular dementia (VaD), mild ambiguous (MA–cognitive problems, but not severe enough for diagnosis of dementia), and healthy older adults. CC outlines obtained from midsagittal magnetic resonance images were divided into 99 equally spaced widths. Factor analysis of these callosal widths identified 10 callosal regions. Multivariate analysis of variance revealed significant group differences for anterior and posterior callosal regions. Post-hoc pairwise comparisons of CC regions in patient groups as compared to the control group (controlling for age) revealed trends toward smaller anterior and posterior regions, but not all were statistically significant. As compared to controls, significantly smaller anterior and posterior CC regions were found in the AD group; significantly smaller anterior CC regions in the VaD group; but no significant CC regional differences in the MA group. Findings suggest that dementia-related CC atrophy occurs primarily in the anterior and posterior portions. (JINS, 2008, 14, 414–423.)
Primary Sjögren’s syndrome impact on smell, taste, sexuality and quality of life in female patients: A systematic review and meta-analysis

Abstract Objectives: The aim of this study is to assess the impact of dryness caused by primary Sjögren’s Syndrome (pSS) on smell, taste and sexual function in female patients, and its influence on quality of life. Methods: Electronic databases including MEDLINE via Ovid, Web of Science, SCOUPUS, EMBASE and COCHRANE LIBRARY were searched until April 2016. Studies that assessed the function of smell, taste and sexuality in pSS patients, defined by the American European Consensus Group (AECG) criteria. Standardized mean differences (SMD) for individual studies using random-effects meta-analysis were feasible. Results: Five studies incorporated 378 participants were included in the quantitative synthesis. The impact of pSS vs. healthy controls was: smell SMD −0.78 (95% CI −1.29 to −0.27); taste SMD −1.01 (95% CI −1.54 to −0.49); total sexual function SMD −0.93 (95% CI −1.22 to −0.64); physical and mental component of the quality of life SMD −1.28 (95% CI −1.65 to −0.90) and SMD −0.83 (95% CI −1.27 to −0.40) respectively; anxiety and depression SMD 0.61 (95% CI 0.02, 1.20) and SMD 0.79 (95% CI 0.43 to 1.15), respectively. Conclusion: pSS has a negative impact on smell, taste, sexual function and quality of life in women.
A safety evaluation of brentuximab vedotin for the treatment of Hodgkin lymphoma

ABSTRACT Introduction: Brentuximab vedotin is an anti-CD30 monoclonal antibody-drug conjugate approved for treating relapsed or refractory Hodgkin lymphoma. The pivotal trial demonstrated brentuximab vedotin’s efficacy and manageable toxicity profile with peripheral neuropathy and neutropenia being the most common side effects. The phase I study of brentuximab vedotin combined with ABVD or AVD revealed its contraindication with bleomycin due to pulmonary toxicity. As trials continue to investigate the drug in frontline and relapsed settings, emerging safety data will further define brentuximab vedotin’s role in managing Hodgkin lymphoma. Areas covered: This article reviews the current literature on brentuximab vedotin in Hodgkin lymphoma treatment, both as a single agent and in combination regimens. The review focuses on safety findings from clinical trials, expected adverse events, and rare serious toxicities. Expert opinion: Brentuximab vedotin is a breakthrough antibody-drug conjugate that may provide new options in earlier lines of therapy for Hodgkin lymphoma. Results from the ongoing phase III trial comparing ABVD to AVD + brentuximab vedotin will inform whether brentuximab vedotin adds benefit to frontline therapy over the current standard of care. The optimal duration of treatment and brentuximab vedotin’s potential as an alternative to radiation in early stage disease still warrant investigation.
Applying the technology acceptance model to Iranian engineering faculty libraries

Purpose – The purpose of this research is to study the determinant factors in the acceptance of information technology (IT) by librarians in the libraries of engineering faculties of public universities in Tehran.Design/methodology/approach – The Technology Acceptance Model (TAM) is used as the research framework and the applicability of this model on the research population is studied. The constructs of TAM include its perceived usefulness, perceived ease of use, attitude toward use, and the intention to use IT. These are the independent variables that affect the dependent variable of IT use. The first six hypotheses of the research have been based on inter‐relationships between each pair of variables in the TAM. The applicability of the TAM model on the population of librarians is the seventh hypothesis. The survey method was applied for collecting data, using a questionnaire. The studied population included 160 librarians and the questionnaire was sent to all of them.Findings – The research findings in.
Antisense HEMA 1 RNA Expression Inhibits Heme and Chlorophyll Biosynthesis in Arabidopsis 1

5-Aminolevulinic acid (ALA) is a precursor in the biosynthesis of tetrapyrroles including chlorophylls and heme. The formation of ALA involves two enzymatic steps which take place in the chloroplast in plants. The first enzyme, glutamyl-tRNA reductase, and the second enzyme, glutamate-1-semialdehyde-2,1-aminomutase, are encoded by the nuclear HEMA and GSA genes, respectively. To assess the significance of the HEMA gene for chlorophyll and heme synthesis, transgenic Arabidopsis plants that expressed antisense HEMA1 mRNA from the constitutive cauliflower mosaic virus 35S promoter were generated. These plants exhibited varying degrees of chlorophyll deficiency, ranging from patchy yellow to total yellow. Analysis indicated that these plants had decreased levels of chlorophyll, non-covalently bound hemes, and ALA; their levels were proportional to the level of glutamyl-tRNA reductase expression and were inversely related to the levels of antisense HEMA transcripts. Plants that lacked chlorophyll failed to survive under normal growth conditions, indicating that HEMA gene expression is essential for growth.
Hardpan and maize root distribution under conservation and conventional tillage in agro-ecological zone IIa, Zambia

Hardpans (plough/hoe pans) are commonly believed to restrict plant root growth and crop yields under conventional small-scale agriculture in sub-Saharan Africa. This study questions the notion of widespread hardpans in Zambia and their remedy under conservation tillage. Soil penetration resistance was measured in 8x12 grids, covering 80 cm wide and 60 cm deep profiles in 32 soil pits. Large and fine maize roots were counted in 8x6 grids. Soil samples from mid-rows were analysed for pH, exchangeable H+, exchangeable Al3+, cation exchange capacity, total N and extractable P (Bray 1) at six depths from 0-10 to 50-60 cm. Cultivation-induced hardpans were not detected. Soils under conservation tillage were more compact at 5 cm depth than soils under conventional tillage. No differences in root distributions between conservation and conventional tillage were found. Maize ( Zea mays L.) roots were largely confined to a relatively small soil volume of about 30 cm x 30 cm x 30 cm. Root growth appeared to be restricted by a combination of low concentrations of N and P. Soil acidity and Al saturation appeared to play a minor role in root distribution. L-shaped taproots in soils under manual tillage reported earlier were not necessarily due to hardpans, but may rather be caused by temporarily dry, impenetrable subsoils early in the rain season. There is no scientific basis for the recommendation given to farmers by agricultural extension workers to “break the hardpan ” in fields under manual or animal tillage in the study areas. Key Words: Soil acidity, Zea mays
The decline and fall of the IGF‐I receptor

This review examines the effect of targeting the insulin‐like growth factor 1 receptor (IGF‐IR) in human cancers. The results are disappointing. The causes for the failure are discussed, as well as the possible use of the IGF‐IR as a secondary target. J. Cell. Physiol. 228: 675–679, 2013. © 2012 Wiley Periodicals, Inc.
E-Learning and ICT Integration in Colleges and Universities in Saudi Arabia

In 2002, GOTEVOT, the government authority responsible for the Kingdom of Saudi Arabia's technical education and vocational training, established the E-Learning Training and Resources Centre. The Centre provides an e-library of more than 50,000 books and 3,000 training programs for lifelong learning and community services with electronic training portfolios. The organization publishes its technical and vocational courses in both Arabic and English on the web.
Red cell glucose‐6‐phosphate dehydrogenase status and pyruvate kinase activity in a Nigerian population

Summary Glucose‐6‐phosphate dehydrogenase A− (G6PD A−) deficiency is a common enzymopathy in Africa that sporadically leads to manifest haemolytic anaemia. It is not exactly known how far the haematological status of individuals with either homozygous or heterozygous G6PD A− deficiency differs from that of individuals with normal G6PD activity. In a field study in Nigeria, we determined G6PD gene variants, the corresponding G6PD and pyruvate kinase (PK) activities, and basic haematological parameters in clinically healthy individuals, who were, in part, asymptomatically infected by malaria parasites. Red blood cell counts and haemoglobin levels were lower in G6PD A− deficient than in G6PD normal subjects. PK activities were higher in G6PD deficients, indicating a younger red cell population in these individuals. These findings suggest that G6PD A− deficiency is accompanied by chronic subclinical haemolysis. As a consequence, the reduced life span of red cells leads to an impaired diagnosis of G6PD heterozygosity when applying routine biochemical methods.
Somatotype and size of elite female basketball players

The aim of this study was to compare the somatotype and size of elite female basketball players in terms of playing position and team performance. Anthropometry and somatotype data were collected on 168 players from 14 countries before the Women's World Basketball Championship, Australia, 1994. There were 64 guards (mean ± s: age 25.4 ± 3.3 years, height 1.72 ± 0.06 m, mass 66.1 ± 6.2 kg, somatotype = 2.9 – 3.9 – 2.6), 57 forwards (age 25.2 ± 3.8 years, height 1.81 ± 0.06 m, mass 73.3 ± 5.9 kg, somatotype = 2.8 – 3.5 – 3.2) and 47 centres (age 24.1 ± 3.1 years, height 1.90 ± 0.06 m, mass 82.6 ± 8.2 kg, somatotype = 3.2 – 3.1 – 3.4). Mean somatotypes by position were significantly different (F = 7.73, P < 0.01). Guards had greater mesomorphy than centres and less ectomorphy than forwards and centres. When discriminant function analysis was applied to endomorphy, mesomorphy, ectomorphy, age, height and mass, only height, mass and ectomorphy entered (Wilks' λ = 0.351, F = 31.40, P < 0.000), 70% of the variance was accounted for, and 72% of players were correctly classified. In the four top versus four bottom teams, guards were taller and more ectomorphic, forwards were taller, with lower mesomorphy and higher ectomorphy, and centres did not differ. Thus there are some differences in somatotypes by position and team placing, but the combination of height, mass and ectomorphy provide the best differentiation by position.
Development of a Human-Murine Chimeric Immunoglobulin M Antibody for Use in the Serological Detection of Human Flavivirus Antibodies

ABSTRACT Current diagnosis of human flaviviral infections relies heavily on serological techniques such as the immunoglobulin M (IgM) antibody capture enzyme-linked immunosorbent assay (MAC-ELISA). Broad application of this assay is hindered by a lack of standardized human positive-control sera that react with the wide variety of flaviviruses that can cause human disease, e.g., dengue virus (DENV), West Nile virus (WNV), yellow fever virus (YFV), Japanese encephalitis virus (JEV), and St. Louis encephalitis virus (SLEV). We have created a human-murine chimeric antibody combining the variable regions of the broadly flavivirus cross-reactive murine monoclonal antibody (MAb) 6B6C-1 and the constant region of human IgM to produce a standardized reagent capable of replacing human positive-control sera in a MAC-ELISA for the diagnosis of all human flaviviral infections. The human-murine chimeric IgM antibody secreted from plasmid-transformed Sp2/0-Ag14 cells had a level of serological activity identical to that of 6B6C-1 as measured by ELISA, immunoblotting, and MAC-ELISA for multiple members of the flavivirus genus, including WNV, SLEV, YFV, DENV, and JEV.
Analysis, occurrence, and toxic potential of pyrethroids, and fipronil in sediments from an urban estuary

Eight pyrethroids and fipronil and its three major degradates were analyzed in urban estuarine sediments that exhibited a range of toxic effects to an amphipod test species. Sediments from Ballona Creek, an urban estuary in Southern California (USA), collected during three dry season events were analyzed by gas chromatography with electron capture and negative chemical ionization mass spectrometric detection (GC‐ECD and GC‐NCI‐MS). The two detection methods were in agreement for intermediate levels of pyrethroid contamination (10–50 ng/g dry wt) but deviated for both low and high concentrations (< 5 and > 50 ng/g). Sediments contained total pyrethroids as high as 473 ng/g with permethrin, bifenthrin, and cypermethrin as the most abundant compounds. In contrast, fipronil and its desulfinyl, sulfide, and sulfone degradates were detected at much lower levels (≤ 0.18–16 ng/g). Toxic units estimated for these compounds revealed that bifenthrin and cypermethrin were likely contributors to the mortality observed in tests with the estuarine amphipod Eohaustorius estuarius. Although fipronil was not a likely contributor to the observed mortality, the concentrations detected may be of concern for more sensitive crustacean species. Furthermore, the spatial pattern of pyrethroid contamination and potential toxicity was highly correlated with fine‐grained substrate, which shifted to downstream stations within a three‐month period during the dry season. Environ. Toxicol. Chem. 2010;29:843–851. © 2010 SETAC
Depression, sexually transmitted infection, and sexual risk behavior among young adults in the United States.

OBJECTIVE To measure associations among depression, sexual risk behaviors, and sexually transmitted infection (STI) among white and black youth in the United States. DESIGN Analysis of prospective cohort study data. Wave I of the National Longitudinal Study of Adolescent Health occurred in 1995 when participants were in grades 7 through 12. Six years later, all Wave I participants who could be located were invited to participate in Wave III and to provide a urine specimen for STI testing. SETTING In-home interviews in the continental United States, Alaska, and Hawaii. PARTICIPANTS Population-based sample. A total of 10 783 Wave I (adolescence) and Wave III (adulthood) white and black respondents with sample weight variables. Main Exposures Chronic depression (detected at Waves I and III) and recent depression (detected at Wave III only) vs no adult depression (not detected at Wave III). OUTCOME MEASURES Multiple sexual partners and inconsistent condom use in the past year and a current positive test result for Chlamydia trachomatis, Neisseria gonorrhoeae, or Trichomonas vaginalis (adulthood). RESULTS Recent or chronic depression in adulthood was more common for blacks (women, 19.3%; men, 11.9%) than for whites (women, 13.0%; men, 8.1%). Among all groups (white men and women, and black men and women), adult depression was associated with multiple partners but not with condom use. Among black men, depression was strongly associated with STI (recent: adjusted prevalence ratio, 2.36; 95% confidence interval, 1.26-4.43; chronic: adjusted prevalence ratio, 3.05; 95% confidence interval, 1.48-6.28); having multiple partners did not mediate associations between depression and STI. CONCLUSIONS Integration of mental health and STI programs for youth is warranted. Further research is needed to elucidate how depression may influence the prevalence of STI among black men.
The Effects of Visitor Density and Intensity on the Behavior of Two Captive Jaguars (Panthera onca)

Several researchers have reported significant effects of visitor density and intensity on captive animal behavior. This study determined whether this was the case for 2 captive jaguars housed at the Woodland Park Zoo, Seattle, WA. Subjects were monitored for changes in behavior as a function of visitor density and intensity. The jaguars were observed for 8 hr per week for 29 weeks—March 31 until October 11, 1998—for a total of 230 hr. Continuous frequency sampling was used, and visitor density and intensity were recorded every minute. Parametric statistics were used to test for correlations between behavior and density, intensity, or a combination of the two. Both density and intensity were significant for time spent non-visible for both cats, and intensity showed a significant effect on the female's pacing behavior. In addition, the male cat exhibited a trend for increased aggression based on both visitor density and intensity and a trend of intensity affecting his social behavior. In conclusion, both density and intensity had a significant effect on behavior, with intensity showing a larger effect.
Mixture Modelling of the HEXACO Personality Inventory

II ACKNOWLEDGEMENTS . III TABLE OF CONTENTS . IV LIST OF TABLES . VI LIST OF FIGURES . VIII LIST OF APPENDICES . IX CHAPTER 1: INTRODUCTION . 1 1.1 Latent Variables and Factor Analysis . 2 1.2 Mixture Modeling . 3 1.2.1 Latent Profile Analyses. 4 1.2.2 Factor Mixture Model . 7 1.3 Applications of Mixture Modelling in Psychology . 9 1.4 Applications of Mixture Modeling in Personality Trait Research . 11 1.5 Objectives of the Study . 16 CHAPTER 2: METHODS . 18 2.1 Sample . 18 2.2 Measure . 18 2.3 Analytic Plan and Procedures . 20 2.3. 1 Confirmatory Factor Analyses. 21 2.3. 2 Latent Profile Analyses. 21 2.3. 3 Factor Mixture Model. 23 2.4 Sources of Variance in Mixture Models . 24
THE FREQUENCY OF SLEEP TALKING IN THE LABORATORY AMONG CHRONIC SLEEP TALKERS AND GOOD DREAM RECALLERS

Chronic sleep talkers utter sleep speech under laboratory conditions at a sufficiently frequent rate as to be capable of providing useful material for study. Fifty-three base line experiments consisting of one or more nights of monitored, otherwise undisturbed sleep were performed on 13 paid subjects offering a history of chronic sleep talking. A total of 206 speeches was recorded. Marked individual differences were observed in total frequency of sleep speech episodes as well as differences in tendencies of association with sleep stages. In general, 20 to 25% of speeches are associated with rapid eye movement period sleep and 75 to 80% are associated with non-rapid eye movement sleep. Additional similar experiments were performed on two larger subject pools: one of chronic sleep talkers and another of good dream recallers with a low arousal threshold. Frequencies of sleep speech and association with specific sleep stages are reported for these conditions as well.
The Q‐switched ND: YAG Laser Effectively Treats Tattoos in Darkly Pigmented Skin

background Laser therapy for removal of cosmetic tattoos has been proven efficacious in lighter skin. Few studies have been reported using the Q‐switched neodymium‐yttrium‐aluminum‐garnet (Nd:YAG) laser to treat tattoos in darkly pigmented or type VU skin, however. objective To report results using the Q‐switched Nd:YAG laser to remove tattoos from type VI skin. methods Eight darkly pigmented patients had 15 amateur tattoos treated with the Q‐switched Nd:YAG laser. Treatments numbered three or four on average and were given at 8‐week intervals. Results were rated by the patients and by a panel of four physicians. results Eight of 15 tattoos were rated as 75–95% cleared after therapy. Another five tattoos were 50% cleared. Two tattoos were only 25% cleared, but underwent only two treatments. None of the patients reported any changes in texture of their skin post therapy. Thirteen of 15 tattoos were removed without any change in the color of the involved skin. The other two tattoos were removed with only slight lightening of the skin. conclusion When treating patients in whom there is a significant risk for keloid scarring or destruction of natural pigment as a consequence of tattoo removal, the Q‐switched Nd:YAG laser appears to be an excellent choice of therapy.