Miracle-dz/UniFAR-FTUs huggingface dataset:
Time regained: how the human brain constructs memory for time

Life’s episodes unfold against a context that changes with time. Recent neuroimaging studies have revealed significant findings about how specific areas of the human brain may support the representation of temporal information in memory. A consistent theme in these studies is that the hippocampus appears to play a central role in representing temporal context, as operationalized in neuroimaging studies of arbitrary lists of items, sequences of items, or meaningful, lifelike events. Additionally, activity in a posterior medial cortical network may reflect the representation of generalized temporal information for meaningful events. The hippocampus, posterior medial network, and other regions—particularly in prefrontal cortex—appear to play complementary roles in memory for temporal context. Highlights The hippocampus encodes information about temporal contiguity, order, and event structure. Posterior medial cortical areas represent order across meaningfully coherent events. Prefrontal and subcortical contributions to temporal memory deserve further study.
Exploring Perceptions of Organizational Ownership of Information and Expertise

Beliefs of organizational ownership relate to whether information and knowledge created by an individual knowledge worker are believed to be owned by the organization. Beliefs about property rights affect information and knowledge sharing. This study explored factors that help determine an individual's beliefs about the organizational ownership of information and expertise that he or she has created. Four different situations of organizational ownership (information vs. expertise/internal vs. external sharing) were considered. The study found that a belief in self-ownership was positively associated with organizational ownership - suggesting a collaborative type of ownership situation for both information and expertise and for both internal (intraorganizational) and external (interorganizational) sharing situations. Organizational culture and the type of employee also influenced the beliefs of organizational ownership in all four scenarios. We conclude the paper with implications for practice and future research.
Stability Criteria of Linear Neutral Systems With Multiple Delays

In the present note, stability of linear neutral systems with multiple delays is investigated. By principle of the argument, stability criteria are derived which are necessary and sufficient for asymptotic stability of the neutral systems. The stability criteria need only to evaluate the characteristic function and the argument on the boundary of a certain rectangular region. Several numerical examples are given to illustrate the results
OPTIMIZING THE PROCESS PARAMETERS OF AWJM USING TAGUCHI METHOD AND ANOVA ON INCONEL 625

Inconel 625 has a wide range of applications because of its high resistance to corrosion cracking, pitting, and crevice formation and to a variety of mineral and organic acids along with high thermal fatigue resistance. However conventional machining of Inconel 625 is not so economical and ease, on the other hand non conventional processes like laser cutting, Abrasive Water Jet Machining (AWJM), Electric Discharge Machining (EDM), etc have a very good potential in overcoming these machining difficulties. Among these AWJM is commonly employed for very hard and brittle materials due to its economical and technical significance. In this work, research oriented experimentation on the AWJM of Inconel 625 is planned and being carried out successfully to optimize the input process parameters for fine Surface finish (SR) and high Material removal rate (MRR). Optimization was carried out by these phases SR and MRR are individually optimized as per Taguchi method by Analysis of variance (MINI TAB).
The Evolution of Lake-Effect Clouds and Snow across Lake Michigan

Lake-effect snow is a common occurrence in the late fall and winter downwind of the North American Great Lakes. It forms when cold air flows over relatively warm lake water, creating convective instability in an otherwise stable environment (Niziol et al. 1995). Lake-effect snow storms develop and evolve entirely within a Type I cloud-topped boundary layer; the clouds associated with this type of boundary layer form due to strong vertical motions and heat and moisture transport from the warm water below (Agee 1987). Since the primary source of energy for this type of boundary layer is the temperature difference between the water and the overlying air instead of direct solar radiation, this type of boundary layer can persist for multiple days. Lake-effect storms can have dramatic impacts on the local and regional climate. For example, energy transfers over the lakes produce increases in fall and winter cloudiness, precipitation, and temperature (numerous studies, such as Scott and Huff 1996), decreases in surface pressure (e.g., Petterssen and Calabrese 1959), and alterations in the evolution and movement of cyclones passing over the lakes (e.g., Weiss and Sousounis 1999; Angel and Isard 1997). Societal and economic impacts of lakeeffect storms are generally associated with large snowfall amounts (e.g., Niziol 1987). Lake-effect storms can produce large amounts of snow (frequently observed to be greater than 30 cm in 24 hr) and snowfall rates exceeding 4 cm hr at times. Such large amounts of snow can have large impacts on communities near the lakes, including disruptions to land and air traffic, elevates snow-removal costs, and personal injuries (e.g., Rodriguez et al. 2007). Although lake-effect snow can result in important impacts, its evolution within the lakeeffect boundary layer has not been widely documented. Observations from various cases over Lake Michigan indicate that cloud base is often located between 100 m and 500 m above the lake surface and that cloud droplet concentrations range from 200-700 cm, with higher values in updrafts (Braham 1983, 1990). There is some evidence that cloud base increases with distance across the lake (Agee and Hart 1990, Chang and Braham 1991), which may be the result of entrainment of drier air into the boundary layer. Numerous studies have found the lower portion of the lake-effect boundary layer to be 70-90% snow filled (e.g., Braham 1990; Chang and Braham 1991; Kristovich et al. 2003). Cloud and precipitation development, which is common in lake-effect systems, has been found to enhance boundary layer growth rates in both lake-effect (Chang and Braham 1991, Schroeder et al. 2006) and non-lake-effect cases (Boers and Melfi 1987, Stevens 2007). While many studies have discussed some aspects of the microphysical characteristics of a
Silver segregation and bacterial growth of intraventricular catheters impregnated with silver nanoparticles in cerebrospinal fluid drainages

Abstract Objectives: Intraventricular catheters impregnated with silver nanoparticles are developed to reduce catheter-associated infections in cerebrospinal fluid (CSF) drainages. Silver released from these new catheters should have an anti-microbacterial effect. This study examines the silver ion release and a potential effect of bacterial growth in an in vitro experiment. Methods: Seven original silver-coated ventricle catheters were rinsed thoroughly with an artificial CSF for 6 days. The collecting containers were replaced every 24 hours. In these samples, ion concentrations of silver were determined via trace analysis through atomic absorption spectroscopy. Furthermore, a bacterial growth was conducted on silver-impregnated and non-impregnated catheters. Results: In none of the samples, a concentration of silver ions could be detected. For Staphylococcus aureus, a slightly decreased bacterial growth could be observed with silver-impregnated catheters. Discussion: There is no risk of a toxic effect due to silver release into the CSF. However, the in vivo antibacterial effect has to be further investigated. We recommend clinical trials to prove the oligodynamic and anti-microbacterial effects of silver-impregnated ventricular catheters.
Hydrothermal Synthesis of Cobalt- Doped Hydroxyapatite Nanoparticles: Structure, Magnetic Behaviour, Bioactivity and Antibacterial Activity

This study focuses on the physical, magnetic, biological and antibacterial behavior of cobalt-doped hydroxyapatite (HAp) powder samples. Pure and cobaltdoped HAp nanoparticles were synthesized by hydrothermal method. Calcium nitrate, diammonium hydrogen phosphate and cobalt nitrate were used as precursor materials. The synthesized powders were characterized using x-ray diffraction pattern (XRD), fourier transform infrared spectroscopy (FTIR), eld emission scanning electron microscopy (FESEM), vibrating sample magnetometer (VSM), raman spectroscopy as well as MTT assay and cell adhesion test. Disc diffusion method was used to investigate antibacterial activity of the samples. The results con rmed the substitution of Ca by Co ions in the HAp lattice. In addition, this substitution induced size reduction and morphology change in HAp particles. All cobalt substituted HAp powder samples displayed paramagnetic properties, as opposed to the diamagnetic behavior observed in the pure HAp samples. In addition, these nanoparticles exhibited cell adhesion, cell viability and antibacterial activity against S.aureus bacteria.
THE IMPACT OF PERCEIVED VALUE ON CUSTOMER SATISFACTION AND REPURCHASE INTENTION OF BLACKBERRY USERS IN MANADO

People today are varying with different perception toward their purchasing behavior. They become eager in purchasing product to guarantee they satisfied after used the product. Blackberry smartphone in the last 4 years became very popular in society at global market nowadays. BlackBerry smartphone nowadays in Indonesia is turn into popular smartphone that already have by many people in every group of them. This research wants to study about customer perceived value on customer satisfaction and repurchase intention of BlackBerry users in Manado. The type of research used in this research is Structural Equation Modeling, or SEM is a quantitative study with secondary data collection techniques. This study collected 200 data sample of population of people who used BlackBerry smartphone in Manado. The conclusion of this study is perceived value has significantly effect toward customer satisfaction. Perceived value has positive effect to repurchase intention but did low significant effect. Customer satisfaction has positive and significant effect to repurchase intention. BlackBerry Ltd. company should be more consider about their strategic marketing and management on pricing by giving low cost (low price) to customer without decreasing the quality of product. Keywords : perceived value, customer satisfaction, repurchase intention
A novel access point selection strategy for indoor location with Wi-Fi

The increasing demands on the indoor location service inspire the wide attentions to investigate the indoor position algorithms. Access point (AP) selection is critical important for increasing the estimation accuracy of the indoor location. In this paper, the key features in influencing the accuracy of indoor location systems are investigated. Base on the analysis results, we present an AP selection strategy for indoor location by proposing a novel AP selection index for test point. By using the experiment data, the K-Nearest Neighbor (KNN) and weighted-KNN (WKNN) indoor location methods are carried out to illustrate the performance proposed AP selection strategy. The performance of our AP selection strategy is validated by comparing with the exhaustive AP selection strategy, the fisher AP selection strategy and the largest RSSI strength AP selection strategy. The experiment results show that the proposed AP selection strategy can improve the location accuracy of indoor location with Wi-Fi.
Leflunomide: dermatologic perspective

Abstract Leflunomide, an isoxazole derivative, is a disease-modifying antirheumatic drug. It has successfully been used for the treatment of rheumatoid arthritis as a feasible alternative to methotrexate. Recently, leflunomide has been used in certain dermatologic conditions. Medline/PubMed search revealed only 201 articles of its application in dermatologic conditions, of which 21 were relevant for inclusion. Prime mode of action of leflunomide is through the inhibition of dihydroorotate dehydrogenase, a key enzyme in the de novo pyrimidine synthesis pathway used by lymphocytes for clonal expansion. The current level of evidence and strength of recommendation suggest its use in psoriasis and psoriatic arthritis. However, the use of leflunomide in severe atopic dermatitis, systemic lupus erythematosus, Wegener's granulomatosis, primary Sjögren's syndrome, bullous pemphigoid, dermatomyositis, sarcoidosis and systemic sclerosis still requires further evaluation.
Water‐mediated interactions between DNA and PhoB DNA‐binding/transactivation domain: NMR‐restrained molecular dynamics in explicit water environment

The solution structure of the complex between the transcription factor PhoB DNA‐binding/transactivation domain and DNA was determined by NMR spectroscopy and simulated annealing in a periodic boundary box of explicit water with the particle mesh Ewald method. The refined structures provided better convergence and better local geometry compared with the structures determined in vacuum. The hydrogen bond interactions between the PhoB domain and DNA in the aqueous environment were fully formed. The complex structure was found to be very similar to the crystal structure, particularly at the PhoB‐DNA interface, much more so than expected from the vacuum structure. These results indicate the importance of the proper treatment of electrostatic and hydration influences in describing protein‐DNA interactions. The hydration structures observed for the refined structures contained most of the crystal waters as a subset. We observed that various water‐mediated PhoB‐DNA interactions contributed to the molecular recognition between PhoB and DNA. Proteins 2008. © 2008 Wiley‐Liss, Inc.
SABBATICAL LEAVE AS A "TIME OUT" FROM ACADEMIC JOB STRESS: A TEST OF CONSERVATION OF RESOURCES THEORY by

To test hypotheses derived from Conservation of Resources Theory (COR), research showing the ameliorative effects of a short respite from work on job stress and strain was replicated among academics on a protracted respite–Sabbatical leave. In a quasi-experiment, 16 faculty members from 10 universities in three countries completed measures of job stress, strain and coping resources before, during and after their Sabbatical. They were compared to 148 matched controls who were not on leave during the same period. Analysis of variance detected significant declines in perceived stress and burnout during the respite among those who were on Sabbatical and no changes among the control participants. Furthermore, the respite promoted sense of control, positive affect, and life satisfaction. The results confirm COR and extend the length of leave from work that produces ameliorative respite effects from the days and weeks o previous research to months and years. Studying Stress: The Respite Design Respite research began as a way to examine the impact of job stress on strain using a more rigorous method than most previous job stress research. Over time, studying stress during such between-events respites, especially vacations, emerge as a topic of study in its own right. (Eden, 2001). Respite research uses repeated-measures designs to examine the hypothesized effects of job stress on strain without the causal ambiguity of single-occasion, stress-strain correlations. Workers are observed on the job and during low-stress off-the-job periods, called respites. A respite from work may be a day off, a weekend, a vacation, or some other form of absence from the work setting when the everyday pressures of the job may be absent. On each occasion workers rate both subjective stress to validate the presumed high or low stress of the occasion, and psychological strain as a hypothesized response to stress. Analyzing the data as interrupted time-series design, causal inferences concerning the effects of stress on strain can b drawn (Eden, 1982, 1990, 2001). A recursive pattern of rising and falling subjective job stress and strain, as objective job stress is present and absent, respectively, confirms the hypothesis th stress causes strain. Because a time-series design is relatively free of causal ambiguity, Cook an Campbell (1979) stated that “This design is obviously a very powerful one for inferring causal effects” (p. 222) and rated it very high on internal validity. The rival hypotheses that a reductio in stress and strain caused a respite such as vacation, or that an increase in job stress and strain Deleted: Page Break
The Impact of Significant Others in Motivational Enhancement Therapy: Findings from Project MATCH

Background: Social network support for abstinence has been associated with improved treatment outcomes among samples of individuals with alcohol use disorders. As a result, research studies have focused on the inclusion of significant others (SOs) in the treatment process. Nonetheless, little is known about 1) the specific influence SOs may have on clients during treatment sessions or 2) whether SO within-session behaviors have any relationship to client post-treatment drinking. Method: In the current study, Motivational Enhancement Therapy sessions in which a SO was present were coded using a behavioral coding system designed to measure SO and client within-session language. Results: Relationships were observed between SO and client within-session language. Furthermore, some specific SO categories of language predicted post-treatment client drinking. Conclusions: This study is the first systematic evaluation of SO contributions in substance abuse treatment sessions. Future research examining SO language in the treatment of alcohol use disorders might allow clinicians to avoid contributions from SOs that are associated with poorer drinking outcomes.
A Clinical Study of Competency to Consent to Hospitalization and Treatment in Geriatric Inpatients *

Abstract: This study used a Competency Questionnaire modified for medical surgical patients (CQ‐Med). Twenty‐nine patients (ages 65–94 years) admitted to a geriatric medicine unit were studied. Along with the CQ‐Med, patients were administered several WAIS‐R subtests, the Blessed Dementia Scale (BDS), and Mini Mental State Exam (MMSE). Additionally, a blind forensic evaluation for competency to consent to hospitalization and treatment was performed for the purpose of validation of the CQ‐Med. Results of the study found that, as expected, increased age was correlated with decreasing performance on the CQ‐Med and decreased findings of competence by clinical exam. However, there was great variability within each age group, demonstrating individual differences in the progress of declining competency. CQ‐Med scores also correlated well with the WAIS‐R subtest raw and scaled scores. Scores on the MMSE and BDS were less well correlated. The CQ‐Med may be a useful adjunct in assessing declining competency in geriatric patients.
Cloning and Characterization of Two Iridoid Synthase Homologs from Swertia Mussotii

Swertia mussotii is an important medicinal plant found on the Qinghai Tibetan Plateau that has great economic and medicinal value. This plant has enjoyed a long history of use as a curative for hepatitis. The biological activity of secoiridoids, including gentiopicroside and swertiamarin, has been mainly tested for its anti-hepatitis effects. Here, we identify two candidate genes (SmIS1 and SmIS2) that are homologues of iridoid synthase and that are components of the secoiridoid pathway in S. mussotii. Using sequencing and phylogenetic analyses, we confirm that SmIS1 and SmIS2 contain six conserved short-chain dehydrogenases/reductase (SDR) motifs and thus belong to the P5βRs group. The two purified Escherichia coli-expressed proteins reduced 8-oxogeranial to both nepetalactol and iridodials. A comparison of the kinetic parameters of SmIS1 and SmIS2 recombinant proteins revealed that SmIS2 has a lower affinity than SmIS1 for 8-oxogeranial. Transcript levels of the two genes were analysed in three different tissues of S. mussotii using semi-quantitative RT-PCR and RT-qPCR. SmIS1 and SmIS2 expression levels were more abundant in leaves and stems. This investigation adds to our knowledge of P5βRs genes in the secoiridoid synthesis pathway and provides candidate genes for genetically improving S. mussotii by enhancing secondary metabolite production.
RAPID RISK ASSESSMENT Emergence of resistance to ceftazidime-avibactam in carbapenem-resistant Enterobacteriaceae 12 June 2018

Reports on the emergence of CAZ-AVI-R CRE soon after its launch represent a public health threat in the EU/EEA and beyond, with the potential for adverse patient outcomes in various settings. In the EU/EEA, only sporadic cases (two patients in two different countries) have so far been reported, but CAZ-AVI-R CRE will most probably have the propensity to spread within healthcare settings and across borders, as has been seen for other CRE.
Bioavailability of dissolved organic nitrogen and carbon from nine rivers in the eastern United States

Dissolved organic nitrogen (DON) and carbon (DOC) often dominate the dissolved nitrogen and organic carbon fluxes from rivers, yet they are not considered to affect coastal water quality because of their assumed refractory nature. The objective of this study was to quantify DON and DOC bioavailability to bacteria in 9 rivers on the east coast of the United States during a 6 d dark bioassay experiment. Water was collected from the freshwater portion of a forest stream in New Jer- sey (Forest 17a), and from the Bass (New Jersey), Delaware (New Jersey), Hudson (New York), Altamaha (Georgia), Savannah (Georgia), Pocomoke (Maryland), Choptank (Maryland), and Peconic (New York) Rivers during base-flow conditions. DON concentrations ranged from 1 to 35 µM and comprised 8 to 94% of the total dissolved nitrogen (TDN) in these rivers. Bioassay results indicate that 23% (±4) of the DON (2 ± 1 µM) was bioavailable in all the rivers except the Bass and Pocomoke, where no DON consumption was measured. Of the TDN consumed by bacteria, DON comprised 43% (±6), demonstrating that DON is an important nitrogen source for bacteria. In contrast, only 4% (±1) of DOC (12 ± 3 µM), was bioavailable in the 9 rivers. Percent-wise, 8 times more DON was consumed relative to DOC in 6 of the rivers, demonstrating that DON cycles faster than DOC. Overall, our study demonstrates that DON is an important part of the TDN pool that needs to be incorporated into coastal nitrogen loading budgets because it is bioavailable on the order of days.
Taxonomical study for some species of Vicia L . ( fabaceae family )

present paper biosystematics studying four species: Viciamonantha, Viciapalaestina, This Viciatenuifolia, Viciavillosa which belong to fabaceae family. This results based on morphologicl, pollen grain, geographical and useful taxonomic attributes on the specific level, numarical taxonomy.