Miracle-dz/UniFAR-FTUs huggingface dataset:
Dielectric strength of SF6 substitutes, alternative insulation gases and PFC-gas-mixtures

Sulphur hexafluoride (SF6) is the most common insulation gas in high voltage technology because of the electron attachment (electron affinity) SF6 has a three times higher dielectric strength at 0.1 MPa compared to air. Beside this SF6 has the most known global warming potential (GWP) and there is demand for alternative insulation gases. SF6 has a non-linear and air a nearly linear dependency between pressure and electric strength. Measurement results in the quasi-homogeneous field shown that Paschen's law is valid for air and not for SF6 and electronegative gases e.g. Nitrile and Ketone. However electronegative gases due to the electron attachment have a significant higher insulation performance compared to natural gases. Therefore gases with a high dielectric strength are advantageous for technical applications. However the boundary conditions like design pressure, electric stress and operating temperature range has to be considered. This investigation shows basic results of the dielectric strength of air, CO2, SF6 and C3F7CN in dependency to the pressure and sparking distance in the quasi-homogeneous field up to 1 MPa pressure.
Antibodies to gliadin, endomysium, and tissue transglutaminase for the diagnosis of celiac disease.

BACKGROUND Tissue transglutaminase has recently been identified as the main autoantigen recognized by antiendomysial antibodies in celiac disease. Serum immunoglobulin (Ig)A antibodies to tissue transglutaminase (tTG-ab) determined by an enzyme-linked immunosorbent assay (ELISA) technique have been reported to correlate closely with IgA antiendomysial antibodies (EMA). The purpose of this study was to assess the sensitivity, specificity, and predictive value of tTG-ab measured by a commercially available ELISA technique, compared with those of EMA and IgA antigliadin antibodies (AGA) for the diagnosis of celiac disease. METHODS Twenty-seven serum samples were obtained from patients with untreated celiac disease, 37 from patients who had had gluten withdrawn from their diets for varying time spans, and 34 from control subjects without celiac disease. All were younger than 14 years. Presence of tTG-ab and AGA was determined by ELISA and of EMA by indirect immunofluorescence. RESULTS Twenty-six of 27 serum samples obtained from patients at the time of diagnosis of celiac disease were AGA positive. All 27 (concordance rate 100%) were positive for EMA and tTG-ab. Of the 34 control subjects, 1 was for AGA and 2 for tTG-ab. All 34 were negative for EMA. Sensitivity, specificity, positive predictive value, and negative predictive value within this group were, for tTG-ab: 100%, 94%, 93%, and 100%, respectively; for EMA: all four indexes were 100%; and for AGA: 96%, 97%, 96%, and 97%, respectively. Of the 37 with treated celiac disease, 2 were AGA positive, 9 were EMA positive, and 6 were tTG-ab positive. The concordance rate between EMA and tTG-ab was 100% in the group with untreated celiac disease, 94% in the control subjects, and 76% in the group with treated celiac disease. CONCLUSIONS Immunoglobulin A antibodies to tissue transglutaminase are new, highly sensitive, and specific markers of celiac disease. They can be determined easily by an accurate, comparatively cheap technique and thereby may advantageously replace the EMA marker traditionally used.
TDP-43 subtypes are associated with distinct atrophy patterns in frontotemporal dementia

Background: We sought to describe the antemortem clinical and neuroimaging features among patients with frontotemporal lobar degeneration with TDP-43 immunoreactive inclusions (FTLD-TDP). Methods: Subjects were recruited from a consecutive series of patients with a primary neuropathologic diagnosis of FTLD-TDP and antemortem MRI. Twenty-eight patients met entry criteria: 9 with type 1, 5 with type 2, and 10 with type 3 FTLD-TDP. Four patients had too sparse FTLD-TDP pathology to be subtyped. Clinical, neuropsychological, and neuroimaging features of these cases were reviewed. Voxel-based morphometry was used to assess regional gray matter atrophy in relation to a group of 50 cognitively normal control subjects. Results: Clinical diagnosis varied between the groups: semantic dementia was only associated with type 1 pathology, whereas progressive nonfluent aphasia and corticobasal syndrome were only associated with type 3. Behavioral variant frontotemporal dementia and frontotemporal dementia with motor neuron disease were seen in type 2 or type 3 pathology. The neuroimaging analysis revealed distinct patterns of atrophy between the pathologic subtypes: type 1 was associated with asymmetric anterior temporal lobe atrophy (either left- or right-predominant) with involvement also of the orbitofrontal lobes and insulae; type 2 with relatively symmetric atrophy of the medial temporal, medial prefrontal, and orbitofrontal-insular cortices; and type 3 with asymmetric atrophy (either left- or right-predominant) involving more dorsal areas including frontal, temporal, and inferior parietal cortices as well as striatum and thalamus. No significant atrophy was seen among patients with too sparse pathology to be subtyped. Conclusions: FTLD-TDP subtypes have distinct clinical and neuroimaging features, highlighting the relevance of FTLD-TDP subtyping to clinicopathologic correlation.
Evidence of Intact Histatins in the in vivo Acquired Enamel Pellicle

Understanding the composition and function of the acquired enamel pellicle (AEP) has been a major goal in oral biology. The aim of this study was to test the hypothesis that intact histatins are part of the in vivo AEP and that histatins after adsorption to HA have effects on in vitro enamel demineralization. This is the first study demonstrating the presence of intact histatins in vivo in the AEP. The in vitro experiments show that all naturally occurring histatins in the AEP have the potential to provide some level of protection against acid injury.
The Effect of Saliva and Oral Intake on the Tensile Properties of Sutures: An Experimental Study

The plastic surgeon often operates in the oral cavity. Little or no information exists regarding the effect of saliva and oral intake upon the tensile properties of suture. Polyglactin 910 (Vicryl) and chromic gut were studied. Five sutures of each type were subjected to saline, saliva, milk, or soy milk over different durations of exposure. Suture breaking strength was tested. A 4-way interaction between suture type, size, liquid, and time was significant (P = 0.0046). Sutures soaked in saliva were significantly weaker. No significant difference was observed between sutures soaked in milk or soy. Saliva appears to enhance degradation rates in both sutures. Suture selection in the oral cavity should be predicated upon the demands of the repair and surgeon's preference. Postoperative feeding instructions should limit tension across mucosal repairs, but the selection of formula should be based upon nutritional requirements and preferences of the child rather than concern over suture degradation.
Cardiac Computed Tomography versus Echocardiography in the Assessment of Stenotic Rheumatic Mitral Valve

There are different clinical cardiac applications of dual source computed tomography (DSCT). Here, we aimed to compare the DSCT with the transthoracic echocardiography (TTE) for evaluating the Wilkins score and planimetric mitral valve area (MVA) of a rheumatic stenotic mitral valve.
Expression of proliferation‐associated proteins (proliferating cell nuclear antigen and Ki‐67 antigen) in Bowen's disease

Bowen's disease and invasive squamous cell carcinoma arising in Bowen's disease (Bowen's carcinoma) were investigated immunohistochemically with regard to their expression of proliferating cell nuclear antigen (PCNA) and the Ki‐67 antigen. Both proliferation‐associated proteins were found in all layers of the tumours, and were present in nuclei of any size and shape. The nucleoli lacked PCNA immunoreactivity, but they expressed the Ki‐67 antigen. The PCNA labelling index was 36.9±12.6% in Bowen's disease (n= 16), and 40.7±11.0% in Bowen's carcinoma (n=3). The Ki‐67 antigen labelling index was 43.6±16.7% in Bowen's disease (n=16), and 51.7±11.6% in Bowen's carcinoma (n=3).
A comparison of the statistical power of different methods for the analysis of cluster randomization trials with binary outcomes

Cluster randomization trials are randomized controlled trials (RCTs) in which intact clusters of subjects are randomized to either the intervention or to the control. Cluster randomization trials require different statistical methods of analysis than do conventional randomized controlled trials due to the potential presence of within‐cluster homogeneity in responses. A variety of statistical methods have been proposed in the literature for the analysis of cluster randomization trials with binary outcomes. However, little is known about the relative statistical power of these methods to detect a statistically significant intervention effect. We conducted a series of Monte Carlo simulations to examine the statistical power of three methods that compare cluster‐specific response rates between arms of the trial: the t‐test, the Wilcoxon rank sum test, and the permutation test; and three methods that compare subject‐level response rates: an adjusted chi‐square test, a logistic‐normal random effects model, and a generalized estimating equations (GEE) method. In our simulations we allowed the number of clusters, the number of subjects per cluster, the intraclass correlation coefficient and the magnitude of the intervention effect to vary. We demonstrated that the GEE approach tended to have the highest power for detecting a statistically significant intervention effect. However, in most of the 240 scenarios examined, the differences between the competing statistical methods were negligible. The largest mean difference in power between any two different statistical methods across the 240 scenarios was 0.02. The largest observed difference in power between two different statistical methods across the 240 scenarios and 15 pair‐wise comparisons of methods was 0.14. Copyright © 2007 John Wiley & Sons, Ltd.
iSchools and non-iSchools in the USA: An examination of their master's programs

Discussions have been carried out in recent years regarding the emergence of iSchools in the field of library and information science (LIS). One theme in the discussions centres on whether those iSchools, deriving from LIS programs, are indeed different from other non-iSchools of the field. To address this question, five iSchools and five non-iSchools that host the ALA-accredited master’s program are compared in terms of program requirements, core courses, concentrations/specializations, and other related parameters. Few distinctive differences are observed between the two groups except for more course offerings by the iSchools and higher number of concentrations/specializations among the noniSchools. This study also examines issues concerning the iSchool movement (e.g., exclusiveness) based on the findings obtained. Although branding is a common practice, it is the collaboration and interaction among all the schools, with or without the “i” prefix, that would truly advance the information field in general and facilitate information education in particular.
Failure Risk Estimates After Dental Implants Placement Associated With Plasma Rich in Growth Factor-Endoret in Osteoporotic Women Under Bisphosphonate Therapy

AbstractThere is disagreement as to whether it is safe to place implants in patients under bisphosphonates (BPs) therapy owing to the risk for developing BP-related osteonecrosis of the jaws (BRONJ). The American Association of Oral and Maxillofacial Surgeons recommends that dental implants should be avoided in oncologic patients treated with intravenous BPs. Conversely, for patients receiving oral BPs, dental implant placement is not explicitly contraindicated even if a cautious approach is suggested. The aim of the current study was to assess the risk level as related to adverse events such as implant failure and BRONJ in a large cohort of osteoporotic patients submitted to implant placement and concomitant application of plasma rich in growth factor (PGRF)-Endoret. The clinical charts of 235 middle-aged women under oral BPs therapy for osteoporosis, who underwent positioning of 1267 dental implants, were reviewed. The implants were always positioned in association with PRGF-Endoret. The outcomes were implant failure and BRONJ. A model based on personal risk factors distribution was used for risk assessment. Sixteen implants were lost in 16 patients up to 120 months of follow-up, leading to a survival of 98.7% and 93.2% on an implant basis and patient basis, respectively. No cases of BRONJ were reported. In line with the current literature, the present data show that the risk for developing BRONJ associated to dental implant surgery remains low for patients receiving oral BPs. The use of procedures that could enhance and support healing, such as platelet concentrates, should be recommended.
Impact of Psychological Empowerment, position and Awareness of Audit on Information Security Policy Compliance Intention

This study aims to explore information security policy (ISP) compliance intention through psychological empowerment (PE), position level, and awareness of audit. An analysis was conducted to test the nonlinear partial least square structural model with research hypotheses using WarpPLS 5.0. The results will be summarized as follows. 1) Position level negatively affects intention to ISP compliance. 2) Awareness of audit positively affects compliance information security policy intention. 3) PE has a moderating effect on the links between awareness of audit and position level. This study provides practical and useful guidance for managers in establishing and managing ISP.
Detecting glaucomatous progression using GDx with variable and enhanced corneal compensation using Guided Progression Analysis

Objective To compare detection of glaucoma progression with scanning laser polarimetry using two methods for corneal compensation. Methods Normal, glaucoma suspects and glaucoma patients with 36 months' follow-up meeting the eligibility criteria were prospectively enrolled. All subjects underwent complete eye exam, standard automated perimetry (SAP) and scanning laser polarimetry with variable and enhanced corneal compensation (GDxVCC, GDxECC). SAP progression was determined using the visual-field index (VFI). GDx progression was determined using Guided Progression Analysis software (GDxGPA) and was defined as a repeatable change on two consecutive scans compared with two baseline images using any of three strategies: ≥150 contiguous pixels on the image progression map (A), four or more adjacent segments on the Temporal Superior Nasal Inferior Temporal graph (B) or a significant change in slope of the summary parameter chart (C). Kappa statistics and logistic regression were used for the analysis. Results Thirteen normal, 30 glaucoma suspect and 25 glaucomatous eyes participating in the Advanced Imaging in Glaucoma Study were included. Progression was identified in six eyes (8.8%) using GDxVCC and in eight eyes (11.8%) using GDxECC. SAP progression was detected in seven (10.3%) eyes. Agreement among progression methods using GDxVCC and GDxECC was strongest for method C (kappa=0.57, p=0.002) compared with methods A (kappa=0.41, p=0.01) and B (kappa=0.41, p=0.01). The association between typical scan score (TSS) and overall or individual methods of progression was not significant using VCC or ECC (p>0.05). Conclusions GDxGPA represents a novel approach for detection of glaucomatous progression. GDxVCC and GDxECC demonstrate moderate agreement.
Studies on the mosquitoes of North Arcot district, Madras State, India. 1. Seasonal densities.

Culex vishnui group was the most abundant mosquito in collections by different methods at 3 villages in North Arcot District. The abundance of this and all the other common mosquito species in the area followed the rainfall pattern closely. Mosquito abundance was lowest in the dry hot months from March to May, rose with the onset of the southwest monsoon in June-July, and was highest during and after the northeast monsoon, from October-January. Culex vishnui group was most abundant in 1960, a year in which there was unusually heavy early rainfall followed by heavy rain later in the year.
The effect of EGFR overexpression in inoperable non-small cell lung cancer (NSCLC) patients receiving cisplatin-vinorelbine combination.

Numerous reports suggested that a variety of tumor cell biological markers predict survival (2). The Epidermal growth factor receptor (EGFR; Her1; erb B1) is highly expressed in NSCLC and associated with advanced tumor stage, resistance to standard therapies and poor patient prognosis and can be considered as a predictive biological marker for survival (3-5). Activation of the EGFR signaling pathway has many effects including increased proliferation and angiogenesis and decreased apoptosis. These effects are mediated by a complex series of signaling mechanisms, such as engagement of the mitogen-activated protein kinase (MAPK) and phosphatidylinositol 3 kinase (PI3K) pathways (6).
Child health and living at high altitude

The health of children born and living at high altitude is shaped not only by the low-oxygen environment, but also by population ancestry and sociocultural determinants. High altitude and the corresponding reduction in oxygen delivery during pregnancy result in lower birth weight with higher elevation. Children living at high elevations are at special risk for hypoxaemia during infancy and during acute lower respiratory infection, symptomatic high-altitude pulmonary hypertension, persistence of fetal vascular connections, and re-entry high-altitude pulmonary oedema. However, child health varies from one population group to another due to genetic adaptation as well as factors such as nutrition, intercurrent infection, exposure to pollutants and toxins, socioeconomic status, and access to medical care. Awareness of the risks uniquely associated with living at high altitude and monitoring of key health indicators can help protect the health of children at high altitude. These considerations should be incorporated into the scaling-up of effective interventions for improving global child health and survival.
Use of drug information resources by the community pharmacist in Penang, Malaysia.

PURPOSE This study aimed to identify the types of drug information resources used by community pharmacists in daily practice in Penang, Malaysia. METHOD A cross-sectional based survey was conducted among randomly selected community pharmacists in Penang state, Malaysia. Data was analysed using the Statistical Package for Social Science Students SPSS 13®. Face-to-face interviews were conducted. A total of 85 community pharmacists were approached for this study. Of these, 65 pharmacists participated in the questionnaire survey, a response rate of 78.3%. RESULTS Tertiary drug resources were used by the majority. About 18% were retrieving drug information from the primary drug information resources. Other sources used to provide drug information were leaflets provided by company representatives, professional peers and drug seminars organised by pharmaceutical companies. CONCLUSION The use of tertiary sources of drug information was more common among community pharmacists in Penang, despite the benefits of using primary information.
Assessment of hypothalamic-pituitary function in women after external head irradiation.

To account for hypopituitarism in patients who received 60Co head irradiation for nasopharyngeal neoplasia, hypothalamic-pituitary function was evaluated in 12 women, aged 19–40 yr, 1–13 yr after the irradiation. The hypothalamicpituitary area received a dose of about 6000–6500 rads. Serum basal LH and FSH levels as well as their responses to 25 µg iv LRH were measured by RIA and the results were compared with responses in the early follicular phase of 5 normal cycling women. In 8 of the 12 patients, serum LH, FSH, and PRL levels were also measured before and during the fourth day of clomiphene administration (100 mg/day for 5 days). Among the 12 irradiated patients, 3 had oligomenorrhea, 3 had amenorrhea, and 8 had galactorrhea. The mean basal LH (5.80 ± 0.68 mlU/ml) and FSH (6.23 ± 0.79 mlU/ml) levels and the mean LRH-stimulated peak for LH (31.33 ± 4.26 mlU/ml) and FSH (14.84 ± 1.80 mlU/ml) were significantly (P < 0.01) lower than those of normal controls. The magnitude of individual gonadotropin respo.
De Subitaneis Mortibus: IX. Type A Wolff‐Parkinson‐White Syndrome

A twenty-two-year-old woman with type A Wolff-Parkinson-White syndrome had a long history of paroxysmal tachycardia and died of a stroke. Until the last two years of life the tachycardias responded to medical treatment, but thereafter they could only be terminated with electrical shock. During one such shock her sinus rhythm disappeared and for over a year she had only atrioventricular (A-V) junctional rhythm although paroxysms of tachycardia persisted.Special studies of the heart after death included serial sections of the entire A-V ring. Nonspecific degenerative disease of both atria included the internodal pathways. Both the sinus node artery and the A-V node artery were narrowed by mural thickening. The sinus node was generally intact but virtually all atrionodal connections were degenerated. The A-V node was similarly detached from its atrial connections but was in direct continuity with the His bundle. The right bundle branch was interrupted at its origin. Within the central fibrous body there were numerous lacunae and one long cleft extending from atrial to ventricular septum parallel to the A-V node. Although the cleft contained cells, there was no direct A-V connection. At the right lateral A-V junction a long thin cylinder of Purkinje cells lay parallel to the tricuspid valve ring and connected to the atrium but not the ventricle. Beneath the left atrial appendage there was a fault in the mitral annulus through which there was a direct A-V connection. Most of this connection was composed of P cells and thus resembled the patient's own sinus node. The atrial connection was to Bachmann's bundle, which was extensively degenerated. The ventricular connection was to ordinary working myocardium midway between epicardium and endocardium. Some functional implications of these anatomical findings are discussed.