Miracle-dz/UniFAR-FTUs huggingface dataset:
AROMA

While research on English opinion mining has already achieved significant progress and success, work on Arabic opinion mining is still lagging. This is mainly due to the relative recency of research efforts in developing natural language processing (NLP) methods for Arabic, handling its morphological complexity, and the lack of large-scale opinion resources for Arabic. To close this gap, we examine the class of models used for English and that do not require extensive use of NLP or opinion resources. In particular, we consider the Recursive Auto Encoder (RAE). However, RAE models are not as successful in Arabic as they are in English, due to their limitations in handling the morphological complexity of Arabic, providing a more complete and comprehensive input features for the auto encoder, and performing semantic composition following the natural way constituents are combined to express the overall meaning. In this article, we propose A Recursive Deep Learning Model for Opinion Mining in Arabic (AROMA) that addresses these limitations. AROMA was evaluated on three Arabic corpora representing different genres and writing styles. Results show that AROMA achieved significant performance improvements compared to the baseline RAE. It also outperformed several well-known approaches in the literature.
PRIDE: The proteomics identifications database

The advent of high‐throughput proteomics has enabled the identification of ever increasing numbers of proteins. Correspondingly, the number of publications centered on these protein identifications has increased dramatically. With the first results of the HUPO Plasma Proteome Project being analyzed and many other large‐scale proteomics projects about to disseminate their data, this trend is not likely to flatten out any time soon. However, the publication mechanism of these identified proteins has lagged behind in technical terms. Often very long lists of identifications are either published directly with the article, resulting in both a voluminous and rather tedious read, or are included on the publisher's website as supplementary information. In either case, these lists are typically only provided as portable document format documents with a custom‐made layout, making it practically impossible for computer programs to interpret them, let alone efficiently query them. Here we propose the proteomics identifications (PRIDE) database (http://www.ebi.ac.uk/pride) as a means to finally turn publicly available data into publicly accessible data. PRIDE offers a web‐based query interface, a user‐friendly data upload facility, and a documented application programming interface for direct computational access. The complete PRIDE database, source code, data, and support tools are freely available for web access or download and local installation.
Vitamin D Deficiency Is Widespread in Cancer Patients and Correlates With Advanced Stage Disease: A Community Oncology Experience

The purpose of this study was to correlate serum vitamin D levels with potential clinical variables and to determine the extent of vitamin D deficiency in a large, outpatient oncology practice. One hundred ninety-five consecutive patients referred for consultation at a community radiation oncology center from October 8, 2008 to March 17, 2010 had vitamin D levels ordered. Patients who were deficient in vitamin D were treated with replacement therapy. Demographic and medical data were collected prospectively and subsequently analyzed. Pretreatment baseline patient and tumor characteristics were evaluated with respect to vitamin D concentrations. One hundred and sixty patients were analyzed. A total of 74% of patients had 25-hydroxyvitamin D concentrations considered either deficient (<20 ng/mL) or suboptimal (20–30 ng/mL). Replacement therapy raised serum vitamin D levels by an average of 15 ng/mL (95% CI = 11–18, P < 0.01). Lower than median serum vitamin D levels were associated with stage III disease in univariate analysis [OR = 2.6 (95% CI = 1.1–6.2), p = 0.04] as well as multivariate analysis adjusted for age, sex, body mass index, and season of draw [OR = 3.3 (95% CI = 1.1–9.7), P = 0.03]. Three-quarters of patients in our series had suboptimal or deficient circulating concentrations of 25-hydroxyvitamin D. Low serum vitamin D levels, independent of age, sex, and body mass index, predicted advanced stage disease.
Putative Cerebral Microbleeds in Dogs Undergoing Magnetic Resonance Imaging of the Head: A Retrospective Study of Demographics, Clinical Associations, and Relationship to Case Outcome

Background Cerebral microbleeds (CMBs) are focal intraparenchymal signal voids on gradient‐echo magnetic resonance imaging (MRI), corresponding to regions of chronic hemorrhage. In humans, they are associated with systemic disease and shorter survival times. Although similar findings have been identified in dogs, their epidemiology and clinical correlations have not been investigated. Objective To determine epidemiological features, clinical associations, and associations with outcome for putative CMB‐like foci (putative microbleeds [pMBs]) identified by T2*‐weighted MRI in dogs. Animals Five hundred and eighty‐two dogs undergoing 3T brain MRI between 2011 and 2016. Methods Retrospective case–control study. Demographic, diagnostic, and clinicopathological data were obtained from medical records and phone follow‐up. Demographic variables were compared between dogs with and without evidence of pMBs. For dogs with such evidence, and a subset of matched controls, associations with clinical presentation, concurrent disease, and survival times were evaluated. Results Dogs with pMBs were older (P < .001) and smaller (P = .004) than unaffected dogs. Compared to matched controls, they presented more frequently for vestibular signs (P = .030). Cortical atrophy occurred concurrently with pMBs in 26% (14/54) of dogs. Diagnosed renal disease was not significantly associated with pMBs, but proteinuria was more common in dogs with pMBs than in matched controls (odds ratio = 3.01, P = .005). Dogs with pMBs had a shorter median survival time than did matched controls (P = .011). Conclusions and Clinical Importance Putative microbleeds occurred in 54 of 582 (9.3%) of dogs undergoing brain MRI, but may not be a normal consequence of aging. They were associated with shorter survival time and proteinuria in the study population.
Design of a Fast Learning Classifier for Sleep Apnea Database based on Fuzzy SVM

In this paper, we compared the performance of support vector machine (SVM) and fuzzy SVM (FSVM) for reduction of learning time when classifying large-scale time series data into two classes. The fast learning time of the pattern classiﬁer for large time series data is very useful in decision support systems. Considering the high interest in healthcare, including big data analysis, it is necessary to design a pattern classiﬁer with a fast learning capability. We used large-scale time series data of 32 patients with sleep apnea (SA) for this study. The experiment was conducted by extending the parameter n , of the fuzzy membership function of FSVM, from 1 to 500. The result shows that the shortest learning time of FSVM is 3 s for radial base function (RBF), 17 s for a polynomial, and 35 s for a linear kernel, where the parameter n of the fuzzy membership function is n = 2, n = 433, and n = 4, respectively. The maximum classiﬁcation hit rate of FSVM is 93.23%, and the learning time is signiﬁcantly faster than conventional SVM. Therefore, FSVM can be used as a good classiﬁer for the large-scale time series SA database.
Effect of Fluoridated Milk on Enamel and Root Dentin Demineralization Evaluated by a Biofilm Caries Model

Although some studies suggest an anticaries effect of fluoridated bovine milk (F-milk) on enamel, evidence is still considered weak. Even more uncertain, the effect of F-milk on root caries remains largely unknown. This study evaluated the effect of F-milk on enamel and on root dentin demineralization using a validated Streptococcus mutans biofilm model, simulating a high cariogenic challenge. S. mutans (UA159) biofilms were formed on bovine enamel and root dentin saliva-coated slabs after measuring initial surface microhardness (SH). Biofilms were exposed to 10% sucrose 8×/day and treated 2×/day with either: (1) 0.9% NaCl (negative control), (2) bovine milk, (3) F-milk (5.0 ppm F as NaF) or (4) NaF 0.05% (anticaries-positive control). Medium pH was monitored twice/day, as a biofilm acidogenicity indicator. After 5 days for enamel and 4 days for dentin, biofilms were recovered to analyze: biomass, soluble proteins, viable microorganisms, and extra- and intracellular polysaccharides. Enamel and dentin demineralization were estimated by percentage of SH loss. Results were compared by ANOVA and Tukey’s test. Neither acidogenicity nor biofilm composition differed among treatment groups in biofilms formed on enamel or dentin (p > 0.05). F-milk, however, significantly reduced enamel and dentin demineralization when compared with the negative control (p < 0.05). Also, F-milk was as efficient as 0.05% NaF to reduce enamel (p > 0.05), but not dentin demineralization (p < 0.05). These findings suggest that milk containing 5.0 ppm of fluoride is effective to control enamel caries and that it may be effective on root dentin caries prevention.
Legionellosis linked with a hotel car park – how many were infected?

SUMMARY An outbreak of legionellosis associated with a hotel in Sydney, Australia, and the subsequent epidemiological and environmental investigations are described. Four cases of Legionnaires' disease were notified to the Public Health Unit. A cross-sectional study of 184 people who attended a seminar at the hotel was carried out. Serological and questionnaire data were obtained for 152 (83%) of these. Twenty-eight (18%) respondents reported symptoms compatible with legionellosis. Thirty-three subjects (22%) had indirect fluorescent antibody (IFA) titres to Legionella pneumophila serogroup 1 (Lp-1) of 128 or higher. The only site which those with symptoms of legionellosis and IFA titre ≥128 were more likely to have visited than controls was the hotel car park (adjusted odds ratio [OR] 14·7, 95% confidence interval [CI]: 1·8–123·1). Those with symptoms compatible with legionellosis, but whose IFA titres were < 128 were also more likely to have visited the hotel car park (adjusted OR 4·4, 95% CI: 1·5–12·9). Seroprevalence of Lp-1 antibodies was higher in those who attended the seminar than in a population sample of similar age. Findings suggested that the 4 cases represented a small fraction of all those infected, and highlighted difficulties in defining illness caused by Lp-1 and in interpreting serology.
Long-term impact of Fit and Strong! on older adults with osteoarthritis.

PURPOSE We present final outcomes from the multiple-component Fit and Strong! intervention for older adults with lower extremity osteoarthritis. DESIGN AND METHODS A randomized controlled trial compared the effects of this exercise and behavior-change program followed by home-based reinforcement (n=115) with a wait list control (n=100) at 2, 6, and 12 months. Fit and Strong! combined flexibility, aerobic walking, and resistance training with education and group problem solving to enhance self-efficacy for exercise and maintenance of physical activity. All participants developed individualized plans for long-term maintenance. RESULTS Relative to controls, treatment participants experienced statistically significant improvements in self-efficacy for exercise (p=.001), minutes of exercise per week (p=.000), and lower extremity stiffness (p=.018) at 2 months. These benefits were maintained at 6 months and were accompanied by increased self-efficacy for adherence to exercise over time (p=.001), reduced pain (p=.040), and a marginally significant increase in self-efficacy for arthritis pain management (p=.052). Despite a substantially smaller sample size at 12 months, significant treatment-group effects were maintained on self-efficacy for exercise (p=.006) and minutes of exercise per week (p=.001), accompanied by marginally significant reductions in lower extremity stiffness (p=.056) and pain (p=.066). No adverse health effects were seen. Effect sizes for self-efficacy for exercise and for maintenance of physical activity were 0.798 and 0.713, and 0.905 and 0.669, respectively, in the treatment group at 6 and 12 months. IMPLICATIONS This consistent pattern of benefits indicates that this low-cost intervention is efficacious for older adults with lower extremity osteoarthritis.
A Single-Input Four-Output (SIFO) AC–DC Rectifying System for Vibration Energy Harvesting

An ac-dc rectifying system for vibration energy harvesting is proposed to generate outputs of four different voltage levels with a single power source. The proposed dual-output rectifier uses only four diodes, similar to a conventional single-output full-bridge rectifier. A switched-capacitor down-converter provides two output voltages from a single input from the voltage doubler by using the proposed load balancer with a low design complexity. The proposed system is implemented in a 0.35-μm CMOS process, and it occupies an area of 0.143 mm 2.
Effectiveness of Dyadic and Multi-Party Joint Ventures

Using data from 80 joint-venture (JV) experiences, this article compares the influence on JV effectiveness of two alternative ways of management: relational investment and formal control. Our results show that the adoption of one or another is contingent upon the number of partners: while relational investment significantly influences the effectiveness of dyadic JVs, formal control is pivotal in the case of multi-party JVs.
Anatomical Dolls: Their Use in Assessment of Children Who May Have Been Sexually Abused

ABSTRACT This article examines anatomical dolls in interviews of children who may have been sexually abused from three perspectives. The article summarizes research findings on anatomical dolls, discusses advantages and disadvantages of using them, and describes endorsed doll uses. Although additional, ecologically-valid research is needed on anatomical dolls, the selective use of anatomical dolls, as communication aids, when interviewing children who may be reluctant or unable to describe sexual abuse is warranted.
Toxigenic potential of Fusarium culmorum strains isolated from French wheat

Sixty F. culmorum strains were isolated from wheat grains collected from different wheat-growing areas in France and from different cultivars. The isolates were grown on autoclaved wheat grain to assess their ability to produce trichothecenes and zearalenone. Fungal biomass was evaluated through the ergosterol grain content. All the isolates produced zearalenone (0.39-1660mg kg-1). Thirty-five of the 60 F. culmorum produced nivalenol (0.11-11.7mg kg -1), 12 of 60 produced fusarenone X (0.05-8.42mg kg -1), five of 60 produced 15-acetyldeoxynivalenol (0.48- 27.7mg kg -1), 13 of 60 produced 3-acetyldeoxyni-valenol (0.07-21.0mg kg -1) and 24 of 60 produced deoxynivalenol (0.92-51.9mg kg -1). According to the results, the distribution of the different chemotypes as well as the high and the low mycotoxin-producing Fusarium strains could not be associated to geographical origin.
Metabolomic Changes and Protective Effect of L-Carnitine in Rat Kidney Ischemia/Reperfusion Injury

Background: Although great progress has been made in the pathogenesis and treatment of acute kidney injury (AKI), it still has high incidence and poor prognosis. The present study was performed in order to further understand the metabolomic changes of ischemia/reperfusion (I/R)-induced AKI and the protective effect of L-carnitine on AKI. Methods: Kidney tissues and serum samples were collected at different time points from three groups of rats including control group, I/R group and L-carnitine-pretreated group. High-performance liquid chromatography coupled with mass spectrometry-based metabolomics approach was applied to investigate the characteristic of I/R-induced AKI and the protective effects of L-carnitine in rat kidney I/R model. Antioxidant enzymatic activity and phospholipase A2 activity were determined to validate the metabolic outcomes. Results: Changes in the pattern of endogenous metabolites as a result of kidney I/R injury were readily detected as early as 2 h after reperfusion, and earlier than the increase in blood urea nitrogen and serum creatinine. Twenty-eight differential endogenous metabolites were discovered and structurally identified by MSn analysis. After I/R injury, lysophospholipids, free fatty acids and nitrotyrosine significantly increased, while carnitine and acetyl-carnitine significantly decreased compared to control. Phospholipase A2 activity and malondialdehyde level also increased, while superoxide dismutase activity decreased in kidney I/R injury rats. Treatment of L-carnitine 30 min prior to reperfusion significantly relieved I/R-induced metabolomic changes. Conclusion: I/R-induced AKI could be characterized by oxidative stress and changes in lipid metabolism through metabolomic investigation, and L-carnitine treatment 30 min before reperfusion had protective effects against I/R-induced AKI.
Numerical study of mean flow effect on sound propagation through an aerosol

Previous studies on the sound attenuation and dispersion in an aerosol consisting of air and water droplets have been extended to accommodate mean flow effects. A numerical methodology based on solution of one dimensional, linearized Euler equations in the frequency domain has been developed. The interactions between the fluid and particle phases have been considered to be through Stokesian drag force. First, the verification of the numerical code has been shown for the zero mean flow case with comparative evaluation of results available in literature. Next, the attenuation and dispersion results of both upstream and downstream flows have been presented. The comparison of results suggests that significant deviations exist for attenuation values between the stationary and the mean flow cases at the same frequencies. Keywords: Suspension Acoustics, Finite Difference in Frequency Domain (FDFD), Mean Flow Effect
Direct Electrochemistry of Catalase at a Gold Electrode Modified with Single-Wall Carbon Nanotubes

The direct electrochemistry of catalase (Ct) was accomplished at a gold electrode modified with single-wall carbon nanotubes (SWNTs). A pair of well-defined redox peaks was obtained for Ct with the reduction peak potential at 0.414 V and a peak potential separation of 32 mV at pH 5.9. Both reflectance FT-IR spectra and the dependence of the reduction peak current on the scan rate revealed that Ct adsorbed onto the SWNT surfaces. The redox wave corresponds to the Fe(III)/Fe(II) redox center of the heme group of the Ct adsorbate. Compared to other types of carbonaceous electrode materials (e.g., graphite and carbon soot), the electron transfer rate of Ct redox reaction was greatly enhanced at the SWNT-modified electrode. The peak current was found to increase linearly with the Ct concentration in the range of 8 10 6 ±8 10 5 M used for the electrode preparation and the peak potential was shown to be pH dependent. The catalytic activity of Ct adsorbates at the SWNTs appears to be retained, as the addition of H2O2 produced a characteristic catalytic redox wave. This work demonstrates that direct electrochemistry of redox-active biomacromolecules such as metalloenzymes can be improved through the use of carbon nanotubes.
Generalization of orientational motion in unit quaternion space

A requirement for the humanoid robot's operation in natural environments is that a humanoid robot can effectively adapt to new configurations of the external world. In this paper we address the problem of adaptation, where new robot movements are generated based on data accumulated in related but different situations. Our solution to this challenge is to apply statistical learning, which provides a method to generate robot responses in new situations. Building on our previous work on learning motor primitives [1], we propose a new methodology for task-specific generalization of orientation trajectories, which we encode as Cartesian space Dynamic Movement Primitives. Example trajectories are generalized by applying Locally Weighted Regression in unit quaternion space, using the parameters describing the task as query points into the trajectory database. We show on real-world and simulated tasks that the proposed methodology can be used for statistical learning of orientation trajectories.
Translating Adult Electrophysiology Findings to Younger Patient Populations: Difficulty Measuring 40-Hz Auditory Steady-State Responses in Typically Developing Children and Children with Autism Spectrum Disorder

Background: γ (∼30-80 Hz) brain rhythms are thought to be abnormal in neurodevelopmental disorders such as schizophrenia and autism spectrum disorder (ASD). In adult populations, auditory 40-Hz click trains or 40-Hz amplitude-modulated tones are used to assess the integrity of superior temporal gyrus (STG) 40-Hz γ-band circuits. As STG 40-Hz auditory steady-state responses (ASSRs) are not fully developed in children, tasks using these stimuli may not be optimal in younger patient populations. The present study examined this issue in typically developing (TD) children as well as in children with ASD, using source localization to directly assess activity in the principal generators of the 40-Hz ASSR in the left and right primary/secondary auditory cortices. Methods: 40-Hz amplitude-modulated tones of 1 s duration were binaurally presented while magnetoencephalography data were obtained from 48 TD children (45 males; 7-14 years old) and 42 ASD children (38 males; 8-14 years old). T1-weighted structural MRI was obtained. Using single dipoles anatomically constrained to each participant's left and right Heschl's Gyrus, left and right 40-Hz ASSR total power (TP) and intertrial coherence (ITC) measures were obtained. Associations between 40-Hz ASSR TP, ITC and age as well as STG gray matter cortical thickness (CT) were assessed. Group STG function and structure differences were also examined. Results: TD and ASD did not differ in 40-Hz ASSR TP or ITC. In TD and ASD, age was associated with left and right 40-Hz ASSR ITC (p < 0.01). The interaction term was not significant, indicating in both groups a ∼0.01/year increase in ITC. 40-Hz ASSR TP and ITC were greater in the right than left STG. Groups did not differ in STG CT, and no associations were observed between 40-Hz ASSR activity and STG CT. Finally, right STG transient γ (50-100 ms and 30-50 Hz) was greater in TD versus ASD (significant for TP, trend for ITC). Conclusions: The 40-Hz ASSR develops, in part, via an age-related increase in neural synchrony. Greater right than left 40-Hz ASSRs (ITC and TP) suggested earlier maturation of right versus left STG neural network(s). Given a ∼0.01/year increase in ITC, 40-Hz ASSRs were weak or absent in many of the younger participants, suggesting that 40-Hz driving stimuli are not optimal for examining STG 40-Hz auditory neural circuits in younger populations. Given the caveat that 40-Hz auditory steady-state neural networks are poorly assessed in children, the present analyses did not point to atypical development of STG 40-Hz ASSRs in higher-functioning children with ASD. Although groups did not differ in 40-Hz auditory steady-state activity, replicating previous studies, there was evidence for greater right STG transient γ activity in TD versus ASD.