Miracle-dz/UniFAR-FTUs huggingface dataset:
Capacity Optimization and Precoding on MIMO Channels with Covariance Feedback

In the paper we consider the case of covariance feedback in MIMO communications, where the channel matrix is modelled as a Gaussian random matrix with zero mean and a non-white covariance matrix available at the transmitter through receiver feedback. Although the structure of the optimal input covariance matrix that achieves the ergodic capacity is known, a closed form expression for its eigenvalues is unavailable. In this paper, we propose a water-filling scheme to approximate the capacity-achieving input covariance matrix. Compared to prior work, our proposed solution has the advantage of a simple closed-form expression that makes it easy to implement. We further propose a precoding scheme based on this suboptimal input covariance matrix. Simulation results suggest that under realistic conditions, this preceding scheme offers a 3-5 dB improvement when it is combined with either OSTBC or a spatial multiplexing scheme
Burnout in Mental Health Professionals as Related to Self-Care

Self care is frequently studied and described in modern psychology research and can be defined as any activity one engages in that fuels the body and mind and allows one to function more fully in daily life (Mahoney, 1997). Burnout is another frequently studied phenomenon, especially when considering those who work in mental health professions. It has been suggested that the benefits of self care may influence the prevention of burnout in mental health professionals but this has not been subjected to rigorous empirical evaluation (Carroll, Gilroy, & Murra, 1999; Norcross, 2000). Other research suggests that therapist age, satisfaction with income, client load, and practice setting may have an impact on both job satisfaction and burnout levels (Farber, 1990; Freudenberger, 1990; Bassett & Lloyd, 2001; Maslach, 1978a; Jayaratne, Vinokur-Kaplan, and Chess, 1995; Lloyd, McKenna, & King, 2004; Raquepaw & Miller, 1989). Multiple correlations as well as regression analyses were performed to test hypotheses regarding the relationship between self-care and burnout, and possible effects of years of experience, satisfaction with income, client load, and practice setting on practicing therapists. A significant negative correlation between burnout and self-care was found and burnout scores among practice setting fell in the expected order. Significant differences between self-care scores were found between those in a group setting versus private practice. Additionally, three variables (satisfaction with income, client load discrepancy, and self-care frequency) were determined to best predict burnout scores in this sample. Implications, limitations, and suggestions for future research are also discussed. Degree Type Dissertation Degree Name Doctor of Psychology (PsyD) Committee Chair Michelle R. Guyton, Ph.D. Second Advisor Lisa Christiansen, Psy.D Third Advisor Michel Hersen, Ph.D., ABPP
Primary invasive melanoma and basal cell carcinoma (collision tumor) with blue nevus‐like cutaneous metastases

The simultaneous presence of two disparate neoplasms occurring in the same specimen has been well documented, albeit uncommonly. The juxtaposition of malignant melanoma and basal cell carcinoma (BCC) has been rarely reported in case reports, with most cases describing melanoma in situ and BCC. We present two cases of invasive melanoma (Clark level IV, no microscopic satellites present) intimately associated with BCC, and in areas distinction of the two lesions was difficult. Immunohistochemical studies delineated the two cell populations. In addition, one patient presented with multiple cutaneous metastases, all simulating blue nevi. The metastases occurred in the same anatomical region as the primary tumor, and histologically consisted of pigmented dendritic melanocytes and melanophages in the superficial and mid‐dermis and arranged in a blue nevus‐like lesion. Histologic clues suggesting the possibility of a metastatic melanoma included a sparse lymphocytic infiltrate, the presence of an epithelioid component and atypia of the dendritic melanocytes. However, without appropriate clinical history, the lesions could be overlooked as ordinary blue nevus. Collision tumors containing invasive melanoma and BCC are rare and this is the first report of a collision tumor with blue nevus‐like metastasis. Awareness of this phenomenon and pattern of metastasis, together with the clinical findings will aid in the correct classification of these lesions.
Study of the Usefulness of Clinical and Hematologic Findings in the Diagnosis of Neonatal Bacterial Infections

The purpose of this study was to evaluate the usefulness of clinical and hematologic findings in distinguishing infected from uninfected newborn infants. Of 356 evaluations for infections, 22 (6%) infants were found to have bacterial isolates. Eight of the 52 clinical and historical findings evaluated were found to be statistically associated with infection. Clinical findings of tachypnea/arrhythmia, decreased peripheral perfusion, pallor, hypo- or hyper tension, abdominal distention, irritability, lethargy, and apnea were signifi cantly associated with positive bacterial cultures. Laboratory data found to be significantly associated with infected infants included white blood cell count < 10,000 or ≥20,000/mm 3, absolute neutrophil count < 1,000/mm3, absolute band count > 200/mm3, and neutrophil band forms/mature neutrophils ≥ 0.10. A 5-point scoring system was derived from the data obtained from this study consisting of: ≥ 2 systems involved on clinical assessment; white blood cells < 10,000 or ≥20,000/mm 3; absolute neutrophils < 1,000/mm3; bands/mature neutrophils ≥ 0.10; and age > 1 week. The restrospective use of this scoring system revealed that all infants with life-threatening bacterial infections had three or more of these findings present. All infants suspected of bacterial disease, therefore, who score ≥ 3 points using this system should have antibiotic therapy started and continued until all cultures are negative. In the face of other strong clinical or laboratory evidence of infection, antibiotics should be begun following appropriate cultures, in spite of a low score. So used, the scoring sys tem described can be helpful to clinicians in making decisions concerning newborn infants suspected of bacterial infections.
Oxytetracycline residues in retail chicken eggs in Ibadan, Nigeria

Oxytetracycline residues in chicken eggs from five markets within Ibadan metropolis were determined by high-performance liquid chromatography following solid-phase extraction. Recovery of oxytetracycline was 80.5%–87.8%, whereas 75.2% of the samples contained detectable oxytetracycline with an overall mean residue concentration of 479.0 µg kg−1. Residue concentrations from Iwo Road, Apata, Challenge, Ojoo and Bodija markets were 421, 460, 468, 568 and 476 µg kg−1, respectively. Eggs from Ojoo market had the highest levels, whereas 68.8% of the samples contained residues above the Codex Alimentarius Commission maximum residue limit. The results are of public health interest as they indicate that a greater proportion of eggs being consumed in Ibadan could contain residues above the maximum residue limit, for which unregulated access and indiscriminate use of antibiotics by poultry farmers could be responsible. National surveillance of eggs and other animal products for antibiotic residue and appropriate regulation of antibiotic is recommended to ensure food safety for consumers.
Liver enzyme activity in dogs infected with Babesia canis

The influence of anaemia on alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) activities in dogs infected with B. canis was investigated. Samples of blood and serum from 230 infected dogs were divided into two groups: A (with anaemia) and B (without anaemia). The differences in the activities of the enzymes between both groups were not statistically significant. These results suggest that mild anaemia, as the only factor, has no influence on ALT, AST, or ALP activity in canine babesiosis. However, this study certainly cannot exclude the possibility that a more severe anaemia can have a major effect on the liver.
Resting-state connectivity in the default mode network and insula during experimental low back pain

Functional magnetic resonance imaging studies have shown that the insular cortex has a significant role in pain identification and information integration, while the default mode network is associated with cognitive and memory-related aspects of pain perception. However, changes in the functional connectivity between the default mode network and insula during pain remain unclear. This study used 3.0 T functional magnetic resonance imaging scans in 12 healthy subjects aged 24.8 ± 3.3 years to compare the differences in the functional activity and connectivity of the insula and default mode network between the baseline and pain condition induced by intramuscular injection of hypertonic saline. Compared with the baseline, the insula was more functionally connected with the medial prefrontal and lateral temporal cortices, whereas there was lower connectivity with the posterior cingulate cortex, precuneus and inferior parietal lobule in the pain condition. In addition, compared with baseline, the anterior cingulate cortex exhibited greater connectivity with the posterior insula, but lower connectivity with the anterior insula, during the pain condition. These data indicate that experimental low back pain led to dysfunction in the connectivity between the insula and default mode network resulting from an impairment of the regions of the brain related to cognition and emotion, suggesting the importance of the interaction between these regions in pain processing.
New Venture Decisions-A Literature Review of the Entrepreneurial Heuristics and Biases

New Ventures Decisions are critically important for our society and have been increasingly studied in the management literature. A number of biases can affect the ways in which entrepreneurs and venture capitalists take decisions in the evaluation of new venture opportunities. These biases are not peculiar to the entrepreneurship domain, but, nonetheless, they are susceptible to manifest in entrepreneurs and venture capitalists in their decisionmaking more than in general population. Entrepreneurial evaluation and decision-making have been studied extensively and some studies have made the links to heuristics and biases. We systematically review those studies on the heuristics and biases of entrepreneurs and venture capitalists, based on the common evaluation criteria of new ventures established along dynamic capability view. Our findings suggest that heuristics and bias are useful to explain the evaluation and decision-making in new ventures, however, the scattered extant results are not systematic, occasionally inconsistent, and lack of in-depth discussions. A lot of gaps and future research opportunities were identified.
Atypical Presentations of Hand, Foot, and Mouth Disease Caused by Coxsackievirus A6 — Minnesota, 2014

In June, 2014, the Minnesota Department of Health (MDH) was notified of a suspected varicella case in a child aged 2 years. The patient had a generalized rash with relative sparing of the trunk and was hospitalized overnight for treatment of dehydration. The child's mother, who was near the end of a pregnancy, also had a generalized rash, which included the perineal area. Identifying the cause of the rash was important to determine whether administration of varicella zoster immune globulin was indicated to prevent neonatal varicella. Enterovirus was detected in specimens from the woman and child by reverse transcriptase-polymerase chain reaction (RT-PCR) testing performed at MDH; partial genome sequencing by CDC showed that both patients were infected with coxsackievirus A6 (CVA6), one of the members of the genus Enterovirus that causes hand, foot, and mouth disease (HFMD).
Diagnostic classification of stroke, especially Lacunes.

Evolution and Testing of the Lacunar Hypothesis" by Bamford and Warlow in this issue of Stroke reviews many important aspects of these unique pathologic vascular lesions. I concur with the authors' emphasis on the need to maintain homogeneity in the classification of stroke conditions, specifically lacunes. A stroke classification scheme would ideally be based on 1) risk factor profile such as hypertension, cardiac disease, and diabetes mellitus; 2) clinical features such as transient ischemic attacks (TIAs), time of onset of deficit, pattern of evolution of the deficit, and abnormal neurologic findings; 3) neuroimaging studies such as computed tomography (CT) and magnetic resonance imaging (MRI); 4) vascular anatomy determined by noninvasive carotid studies and angiography; 5) functional studies such as singlephoton emission computed tomography (SPECT), positron emission tomography (PET), and xenon blood flow; 6) natural history such as clinical course and level of recovery; and 7) pathologic anatomy. This scheme of stroke classification would make it possible to devise therapeutic trials involving homogeneous groups of patients and would reduce the risk of two types of errors. One type of error occurs when a specific therapy is reported to be effective because the treated stroke population contained many patients with a benign natural history who would have done well even if they had received no specific treatment. The second type of error occurs when a therapy is reported to be ineffective because the treated stroke population was so large and diverse that one or more homogeneous subgroups in which the treatment was effective were not identified. Many reports have described the "lacunar syndromes" as having nonischemic or even nonvascular etiologies including intracerebral hemorrhage, subdural hematoma, neoplasm, and infectiousinflammatory conditions. The list of nonischemic etiologies continues to proliferate, demonstrating the need for careful neurodiagnostic evaluation of each patient. It is crucial to exclude patients with
Liquidity Creation as Volatility Risk

We show, both theoretically and empirically, that liquidity creation induces negative exposure to volatility risk. Intuitively, liquidity creation involves taking positions that can be exploited by privately informed investors. These investors’ ability to predict future price changes makes their payoff resemble a straddle (a combination of a call and a put). By taking the other side, liquidity providers are implicitly short a straddle, suffering losses when volatility spikes. Empirically, we show that short-term reversal strategies, which mimic liquidity creation by buying stocks that go down and selling stocks that go up, have a large negative exposure to volatility shocks. This exposure, together with the large premium investors demand for bearing volatility risk, explains why liquidity creation earns a premium, why this premium is strongly increasing in volatility, and why times of high volatility like the 2008 financial crisis trigger a contraction in liquidity. Taken together, these results provide a new, assetpricing view of the risks and rewards to financial intermediation. JEL Codes:
Las nuevas tecnologías de información y las mujeres: reflexiones necesarias

Resumen El documento fue presentado como uno de los estudios bases para el debate durante la Reunion de expertos sobre Globalizacion, cambio tecnologico y equidad de genero" (Sao Paulo, Brasil, 5 y 6 de noviembre de 2001), organizada en conjunto por la Unidad Mujer y Desarrollo con la Division de Comercio Internacional de la CEPAL y el Nucleo de Estudios de la Mujer y Relaciones Sociales de Genero de la Universidad de San Pablo. El texto deja claro que las nuevas tecnologias nos introducen en un tiempo de vertigo y de nuevas exclusiones, y que ademas de ser una realidad material son tambien una produccion discursiva con efectos en las instituciones, las politicas publicas y las personas. El estudio revisa una importante literatura teorica, asi como la mayor parte de las investigaciones que dan cuenta de la insercion y relacion de las mujeres con las nuevas tecnologias de informacion y conocimiento. "
Comparison of Neurological Soft Signs between Psychotic and Non Psychotic Patients.

INTRODUCTION Neurological Soft Signs (NSS) are a group of non-specific signs manifested in some psychiatric patients. Till date, most studies have focused on NSS in schizophrenic patients. AIM In the current study, the mean NSS score was compared between psychotic and non psychotic patients. MATERIALS AND METHODS This descriptive analytical study was conducted on 96 hospitalized patients having psychotic disorders. The patients were first examined by a psychiatrist and their axis I diagnoses (according to DSM-IV-TR) were made. Accordingly, the patients were divided into three groups of psychotic (schizophrenic and schizoaffective) and bipolar disorder patients with and without psychotic symptoms. Using a 28-item questionnaire, the patients were neurologically examined and their NNS scores were calculated. The mean scores were compared among the groups. RESULTS Based on the results, the mean NSS score in psychotic patients (schizophrenic and schizoaffective) was higher as compared to that in non-psychotic patients (bipolar disorder patients without psychotic symptoms) and this difference was statistically significant (p<0.0001). CONCLUSION It seems that calculation of NSS score in psychotic patients can help predict the response to pharmaceutical treatment, risk of drug reactions/side effects and prognosis of disease. Drawing a definite conclusion in this regard requires further investigations.
Unilateral cancer-associated retinopathy: a case report

We write to report a rare case of unilateral cancer-associated retinopathy previously undocumented in the literature. Cancer-associated retinopathy is an uncommon paraneoplastic syndrome. It is characterised by retinal antigen autoantibodies causing rod and cone dysfunction and abnormal electroretinography findings with consequent progressive visual loss. Our patient, known to have a primary cervical intraepithelial neoplasia, presented with unilateral blurred vision as well as a disturbance in colour and night vision. Electroretinography findings of reduced a and b waves in the right eye, together with a fundoscopic appearance of a mottled retinal pigment epithelium, attenuated blood vessels and optic disc pallor were consistent with unilateral cancer-associated retinopathy. Posterior subtenon injections of triamcinolone were administered to control active disease. With periocular steroid injections, at 4 years, our patient’s visual acuity remained relatively stable and her condition persisted strictly unilaterally. Cancer-associated retinopathy may be the first presenting sign of an underlying malignancy or may indicate its recurrence. Moreover, in patients with a diagnosed gynaecological malignancy, visual symptoms could reflect cancer-associated retinopathy. In our patient visual symptoms came secondary to the diagnosis of cancer.
Homeostasis, Thymic Hormones and Aging

The thymic-pituitary axis constitutes a bidirectional circuit where the ascending feedback loop is effected by thymic factors of epithelial origin. The aim of the present article is, first, to introduce the idea of an immune-neuroendocrine homeostatic network in higher animals. Next, the relevance of the thymus in this network and the possible role of this gland in the neuroendocrine imbalances associated with aging are discussed. A number of studies are next reviewed which show that the endocrine thymus produces several bioactive molecules, generally called thymic hormones, which in addition to possessing immunoregulatory properties are also active on nervous and endocrine circuits. In particular, the reported activities of thymosin fraction five, thymosin alpha 1 and thymosin beta 4 on β-endorphin, adrenocorticotropic hormone, glucocorticoids, luteinizing hormone-releasing hormone and luteinizing hormone secretion in different animal and cell models are reviewed. The known hypophysiotropic actions of other thymic hormones like thymulin, homeostatic thymus hormone and thymus factor are also summarized, and the impact of aging on pituitary responsiveness to thymic hormones is discussed. As a conclusion, it is proposed that in addition to its central role in the regulation of the immune function, the thymus gland may extend its influence to nonimmunologic components of the body, including the neuroendocrine system. The early onset of thymus involution might, therefore, act as a triggering event which would initiate the gradual decline in homeostatic potential that characterizes the aging process.
TRB3 mediates homocysteine‐induced inhibition of endothelial cell proliferation

Hyperhomocysteinemia (HHcy) has been shown to induce endothelial dysfunction, an early event in the progression of atherosclerosis. However, the underlying mechanism of endothelial cell injury in HHcy has not been clearly elucidated. In this study, we examined the effect of homocysteine on tribbles‐related protein 3 (TRB3)‐mediated cell‐cycle arrest in human umbilical vein endothelial cells (HUVECs). Treatment of HUVECs with homocysteine (0–250 µmol/L) resulted in inhibition of cell proliferation assessed by [3H]‐thymidine incorporation into DNA. Homocysteine induced cell‐cycle arrest in the G1 phase by up‐regulating the protein levels of p27kip1. Under these conditions, homocysteine did not induce endoplasmic reticulum stress. However, homocysteine up‐regulated the expression of TRB3, thus leading to the dephosphorylation of Akt (Thr308). Knock‐down of endogenous TRB3 using siRNA significantly suppressed the inhibitory effect of homocysteine on the proliferation of HUVECs. Homocysteine‐induced TRB3 expression was mediated by the cAMP/cAMP response element‐binding protein (CREB) pathway. These results demonstrate that TRB3 is a critical molecule in the homocysteine‐mediated cell‐cycle arrest in endothelial cells. J. Cell. Physiol. 226: 2782–2789, 2011. © 2011 Wiley‐Liss, Inc.