Miracle-dz/UniFAR-FTUs huggingface dataset:
Antecedents of product satisfaction and brand satisfaction at product receipt in an online apparel shopping context

Abstract This study investigates the antecedents of satisfaction with the product and satisfaction with the brand of consumers when they have received a garment ordered online and tried it on for the first time. We propose four antecedents of product satisfaction and brand satisfaction: (a) brand-based product expectation at purchase, (b) perceived product performance at product receipt, (c) website-visible-attribute expectancy disconfirmation (discrepancy between product expectation and perceived performance of the product attributes that are visible on the website, such as style and color), and (d) website-invisible-attribute expectancy disconfirmation (discrepancy between product expectation and perceived performance of the product attributes that may not be distinguishable on the website, such as fabric, fit, and workmanship). The research design was a 2 (levels of brand-based product expectation) x 2 (levels of perceived product performance) factorial experimental design. We developed two mock-up apparel retailer web pages for the data collection, and 120 participants provided usable responses. The findings revealed that brand-based product expectation and product performance did not influence product or brand satisfaction. Both types of expectancy disconfirmation were determinants of product satisfaction; however, only website-visible-attribute expectancy disconfirmation was the antecedent of brand satisfaction. Based on the findings, theoretical and pragmatic implications are presented.
Optical Imaging of Tumor Hypoxia and Evaluation of Efficacy of a Hypoxia-Targeting Drug in Living Animals

Solid tumors containing more hypoxic regions show a more malignant phenotype by increasing the expression of genes encoding angiogenic and metastatic factors. Hypoxia-inducible factor-1 (HIF-1) is a master transcriptional activator of such genes, and thus, imaging and targeting hypoxic tumor cells where HIF-1 is active are important in cancer therapy. In the present study, HIF-1 activity was monitored via an optical in vivo imaging system by using a luciferase reporter gene under the regulation of an artificial HIF-1-dependent promoter, 5HRE. To monitor tumor hypoxia, we isolated a stable reporter-transfectant, HeLa/5HRE-Luc, which expressed more than 100-fold luciferase in response to hypoxic stress, and observed bioluminescence from its xenografts. Immunohistochemical analysis of the xenografts with a hypoxia marker, pimonidazole, confirmed that the luciferase-expressing cells were hypoxic. Evaluation of the efficacy of a hypoxia-targeting prodrug, TOP3, using this optical imaging system revealed that hypoxic cells were significantly diminished by TOP3 treatment. Immunohistochemical analysis of the TOP3-treated xenografts confirmed that hypoxic cells underwent apoptosis and were removed after TOP3 treatment. These results demonstrate that this model system using the 5HRE-luciferase reporter construct provides qualitative information (hypoxic status) of solid tumors and enables one to conveniently evaluate the efficacy of cancer therapy on hypoxia in malignant solid tumors.
Mesenchymal Stem Cell-Derived Exosomes Improve the Microenvironment of Infarcted Myocardium Contributing to Angiogenesis and Anti-Inflammation

Background/Aims: Bone marrow mesenchymal stem cells (MSCs) widely applied for treating myocardial infarction face survival challenges in the inflammatory and ischemia microenvironment of acute myocardial infarction. The study hypothesized that MSC-derived exosomes play a significant role in improving microenvironment after acute myocardial infarction and aimed to investigate the paracrine effects of exosomes on angiogenesis and anti-inflammatory activity. Methods: MSCs were cultured in DMEM/F12 supplemented with 10% exosome-depleted fetal bovine serum and 1% penicillin-streptomycin for 48 h. MSC-derived exosomes were isolated using ExoQuick-TC. Tube formation and T-cell proliferation assays were performed to assess the angiogenic potency of MSC-derived exosomes. Acute myocardial infarction was induced in Sprague-Dawley rats, and myocardium bordering the infarcted zone was injected at four different sites with phosphate-buffered saline (PBS, control), MSC-derived exosomes, and exosome-depleted MSC culture medium. Results: MSC-derived exosomes significantly enhanced the tube formation of human umbilical vein endothelial cells, impaired T-cell function by inhibiting cell proliferation in vitro, reduced infarct size, and preserved cardiac systolic and diastolic performance compared with PBS markedly enhancing the density of new functional capillary and hence blood flow recovery in rat myocardial infarction model. Conclusions: Exosomes stimulate neovascularization and restrain the inflammation response, thus improving heart function after ischemic injury.
Novel Method for Fabrication of Tri-Gated Poly-Si Nanowire Field-Effect Transistors With Sublithographic Channel Dimensions

A high-performance short-channel tri-gated polycrystalline-silicon nanowire (NW) field-effect transistor is developed by using simple sidewall spacer and lateral etching techniques without employing costly lithographic tools. Channel length of 120 nm and NW thickness of 25 nm can be easily formed by the self-aligned process. The device exhibits superior electrical characteristics because of the strong gate controllability: a subthreshold swing of 102 mV/dec, drain induced barrier lowing of 74.4 mV/V, and extremely high ION/IOFF ratio of 4.4 ×108(Vd=1 V) are obtained.
Glucocorticoid and Androgen Activation of Monoamine Oxidase A Is Regulated Differently by R1 and Sp1*

Monoamine oxidase (MAO) A is a key enzyme for the degradation of neurotransmitters serotonin, norepinephrine, and dopamine. There are three consensus glucocorticoid/androgen response elements and four Sp1-binding sites in the human monoamine oxidase A 2-kb promoter. A novel transcription factor R1 (RAM2/CDCA7L) interacts with Sp1-binding sites and represses MAO A gene expression. Luciferase assays show that glucocorticoid (dexamethasone) and androgen (R1881) increase MAO A promoter and catalytic activities in human neuroblastoma and glioblastoma cells. Gel-shift analysis demonstrates that glucocorticoid/androgen receptors interact directly with the third glucocorticoid/androgen response element. Glucocorticoid/androgen receptors also interact with Sp1-binding sites indirectly via transcription factor Sp1. In addition, dexamethasone induces R1 translocation from the cytosol to the nucleus in a time-dependent manner in both the neuroblastoma and wild-type UW228 cell lines but not in R1 knock-down UW228 cells. In summary, this study shows that glucocorticoid enhances monoamine oxidase A gene expression by 1) regulation of R1 translocation; 2) direct interaction of the glucocorticoid receptor with the third glucocorticoid/androgen response element; and 3) indirect interaction of glucocorticoid receptor with the Sp1 or R1 transcription factor on Sp1-binding sites of the MAO A promoter. Androgen also up-regulates MAO A gene expression by direct interaction of androgen receptor with the third glucocorticoid/androgen response element. Androgen receptor indirectly interacts with the Sp1, but not R1 transcription factor, on Sp1-binding sites. This study provides new insights on the differential regulation of MAO A by glucocorticoid and androgen.
DAYA SAING USAHA PENGGEMUKAN SAPI POTONG PETERNAKAN RAKYAT DI KABUPATEN BOJONEGORO, JAWA TIMUR

The purpose of this study was to analyze the competitiveness on beef cattle fattening small scale business in Bojonegoro. Data processing quantitative methods using PAM (Policy Analysis Matrix). Analysis of competitiveness calculated by the approach of comparative advantage (Domestic Resources Cost Ratio) and competitive advantage (Private Cost Ratio), based on the results of the research value of the DRC and PCR respectively 1 , 04 and 1 , 05, this result shows that fattening beef cattle in Bojonegoro not competitive. Policy implications that can be applied in order fattening beef cattle in Bojonegoro competitiveness is to increase ADBW (Added Daily Body Weight) amounted to 17 , 33 percent, equivalent to 0 , 11 kg per day from the previous ADBW 0 , 55 kg per day, one attempts to do is the provision of input quality feed and concentrates, as well as the necessary counseling to farmers about the importance of quality feed and to improve the ability of farmers needed training and assistance from the Government of Bojonegoro .
Lung cancer screening: making the transition from research to clinical practice

Purpose of review The purpose of this review is to examine the literature on lung cancer screening with an emphasis on the prevalence of cancer in screen-detected nodules. On the basis of the evidence, we will then develop a practical approach to screen-detected lung nodules. Recent findings The first large randomized controlled trial using low-dose computed tomography (LDCT) found that persons undergoing three annual screening examinations with LDCT had a 20% relative reduction in lung cancer mortality as compared with those screened with annual chest X-rays. The probability of cancer in screen-detected nodules depends on their size and whether the nodules are detected on prevalence or incidence screens. The probability of cancer in screen-detected nodules ranges from 2.4 to 5.2%. Management strategies for screen-detected nodules that have been used successfully include careful observation using serial CT imaging, CT-guided fine needle biopsy, and surgery in carefully selected cases. The most frequently used strategies involve serial CT imaging and CT-guided biopsy for larger nodules and those that demonstrate growth on follow-up. Summary There is now evidence that LDCT in carefully selected high-risk populations can lead to better outcomes but the cost effectiveness of mass screening with LDCT is still unknown. Only patients at high risk for cancer should be screened.
Tunable laser operation of Yb:NaY(MoO4)2

CW laser operation of Tm<sup>3+</sup> in Czochralski-grown disordered NaY(WO<sub>4</sub>)<sub>2</sub> crystals is demonstrated. The tunability extends from 1847 to 2069 nm. The maximum slope efficiency and output power amount to ap43% and ap400 mW, respectively.
Ethnic Differences in In-Hospital Place of Death Among Older Adults in California: Effects of Individual and Contextual Characteristics and Medical Resource Supply

Background:Substantial ethnic differences have been reported in the probability that death will occur in a hospital setting rather than at home, in a hospice, or in a nursing home. To date, no study has investigated the role of both individual characteristics and contextual characteristics, including local health care environments, to explain ethnic differentials in end-of-life care. Objectives:The study purpose is to examine ethnic differences in the association between death as a hospital in-patient and individual and contextual characteristics, as well as medical resource supply. Research Design:This study employed a secondary data analysis. Subjects:We used data from the California Death Statistical Master file for the years 1999–2001, which included 472,382 complete cases. These data were geocoded and linked to data from the US Census Bureau and the American Hospital Association. Results:Death as an in-patient was most common for Asian (54%) and Hispanic immigrants (49%) and least common for non-Hispanic whites (36%) and US-born Asians (41%). Medical resource supply variables are of considerable importance in accounting for ethnic differentials in the probability of dying in a hospital. Residual differences in in-hospital site of death were largest for immigrant populations. Conclusions:There are sizeable ethnic differentials in the probability that a death will occur in a hospital in California. These differences are substantially mediated by sociodemographic characteristics of the decedent and local medical care supply. One implication of these findings is that variation exists in the efficiency and quality of end of life care delivered to ethnic minorities.
Ventrolateral medulla in spontaneously hypertensive rats: role of angiotensin II.

We investigated whether angiotensin II (ANG II), endogenous to the ventrolateral medulla (VLM), contributes to cardiovascular regulation in spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto (WKY) rats. The action of ANG II endogenous to the VLM was examined by microinjection of 100 pmol of [Sar1,Thr8]ANG II into either the rostral (R) or caudal (C) VLM. This ANG II antagonist caused depressor and bradycardic responses in the RVLM and pressor and tachycardic responses in the CVLM. The magnitude of the blood pressure responses was significantly greater (P < 0.01 in RVLM and P < 0.05 in CVLM) in SHRs (-27 +/- 3 mmHg in RVLM and 29 +/- 4 mmHg in CVLM) than in WKY rats (-17 +/- 1 and 17 +/- 2 mmHg, respectively). Suppression of tonic activity of RVLM neurons by bilateral injection of muscimol in the RVLM showed that the pressor response produced by ANG II antagonist injection in the CVLM required the integrity of rostral pressor neurons. The present data suggest that ANG II endogenous to RVLM and CVLM acts as a tonic excitatory agent on vasomotor neurons of the VLM. The contribution of ANG II in the RVLM and CVLM to the prevailing level of blood pressure was significantly (P < 0.01) larger in SHRs vs. WKY rats when the effect of ANG II blockade was measured as the change in blood pressure. Blockade of gamma-aminobutyric acid (GABA)A receptors in the RVLM showed that inhibitory GABAergic input to the RVLM was not diminished in this strain. (ABSTRACT TRUNCATED AT 250 WORDS)
Engagement Auditor Industry Specialization and Stock Price Crash Risk: Evidence from China

We investigate the effects of engagement auditor industry specialization on stock price crash risk. Although research on audit partners has been growing, we are not aware of any prior studies that investigate partner-level specialization and crash risk. Using a large sample of Chinese stocks spanning the period 2003-2015, we find a statistically significant and negative association between auditor industry specialization and stock price crash risk. Our mediation tests suggest that audit partner industry specialization decreases the risk of price crash by mitigating earnings manipulation. We further document that the negative association is more pronounced for firms that switch from non-specialist audit partners to specialist audit partners. We also find some evidence that audit partners’ personal characteristics moderate the association between partner specialization and crash risk. Our results remain robust to alternative measures of partner specialization.
Renal and vascular hypertension-induced inflammation: role of angiotensin II

Purpose of reviewWe will focus on the recent findings concerning the inflammatory response in vascular and renal tissues caused by hypertension. Recent findingsAngiotensin II is one of the main factors involved in hypertension-induced tissue damage. This peptide regulates the inflammatory process. Angiotensin II activates circulating cells, and participates in their adhesion to the activated endothelium and subsequent transmigration through the synthesis of adhesion molecules, chemokines and cytokines. Among the intracellular signals involved in angiotensin II-induced inflammation, the production of reactive oxygen species and the activation of nuclear factor-κB are the best known. SummaryThe pharmacological blockade of angiotensin II actions, by angiotensin-converting enzyme inhibitors or angiotensin receptor antagonists, results in beneficial organ protective effects, in addition to the effects of these agents on blood pressure control, that can be explained by the blockade of the angiotensin II-induced pro-inflammatory response. These data provide a rationale for the use of blockers of the renin–angiotensin system to prevent vascular and renal inflammation in patients with hypertension.
FROM TODA'S URGE THEORY TO THE COMMITMENT THEORY OF EMOTIONS

The article presents the theory of ``emotions-as-commitmentsoperators’’ which shows striking similarities with Toda’s system. The article concludes by stressing how the concept of commitments as second-order resources could help simplify Toda’s proposal, and clarify the concepts of motivation and emotions. What are emotions for? What are the added survival bene¢ts for individuals of some species to have them? Such questions are crucial if one is to design adaptive and effective autonomous agents. It is generally thought that emotions appeared a very long time ago, around the time Cybernetics and Systems: An International Journal, 32 :585± 610, 2001 Copyright # 2001 Taylor & Francis 0196-9722/01 $12.00 + . 00 Address correspondence to Michel Aubë, Faculty of Education, Universitë de Sherbrooke, Sherbrooke, Quebec, Canada J1K 2R1. E-mail: maube@courrier.usherb. ca
Respiratory viral infections among children with community-acquired pneumonia and pleural effusion

Abstract Pleural effusion (PE), a complication of community-acquired pneumonia (CAP), is usually attributed to a bacterial infection. Nonetheless, viral infections have not been investigated routinely. We searched for bacterial and viral infections among 277 children hospitalized with CAP. Among these children 206 (74%) had radiographic confirmation, of whom 25 (12%) had PE. The aetiology was established in 18 (72%) PE cases: bacterial (n = 5; 28%), viral (n = 9; 50%), and viral–bacterial (n = 4; 22%) infections were found. Infection by rhinovirus (n = 3), enterovirus, Streptococcus pneumoniae (n = 2 each), Haemophilus influenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, influenza A virus, and respiratory syncytial virus (RSV) (n = 1 each) were detected as probable sole infections. Parainfluenza virus 1/3 + influenza A virus and RSV + influenza A virus (n = 1 each) were identified as mixed viral–viral infections. Probable viral non-bacterial infection was identified in a third of the cases with CAP and PE. It is advisable to investigate viral as well as bacterial infections among children with CAP and PE.
EVALUATING ATTITUDES ON THE QUALITY OF SERVICE OF PEDESTRIAN NETWORKS

The aim of our research is to study opinions of people upon the pedestrian conditions in urban spaces. The goal is to evaluate, based on the perception of citizens, the existence of certain walkability factors that contribute to the quality of service of the pedestrian environment. Walkability factors are related to mobility, connectivity, comfort, safety and convenience. As a result, a pedestrian satisfaction index could be derived, which might reveal the citizens’ quality of life and the need for developing comfortable, healthy and safe pedestrian networks. Results show the willingness of people to walk more, but also the obstacles that prevent them from doing so. Our study is important for the better understanding of walkability issues in urban spaces, especially for developing technology solutions and strategies for local governments in the quest of realizing the vision of the smart city.
Fungal Sinusitis in Patients with AIDS: Report of 4 Cases and Review of the Literature

We report here 3 cases of aspergillus sinusitis in patients with AIDS and the 1st fully described case, to our knowledge, of sinusitis associated with Pseudallescheria boydii in a patient with AIDS. We review the microbiology and pathology of fungal sinusitis in patients with AIDS and the morphologic and clinical features and treatment of P. boydii infection and aspergillus sinusitis. Fungal sinusitis in patients with HIV or AIDS generally occurs later in the course of primary disease with low CD4+ lymphocyte counts (< 50/mm3), unlike bacterial sinusitis which may occur at any time. Differentiation between invasive and noninvasive forms is likely not important, in contrast to fungal sinusitis in noncompromised patients. The number of cases is likely to increase as the number of patients with AIDS increases, patients survive longer, and other opportunistic infections are prevented or treated. Causative agents are likely to be resistant to fluconazole, which is in widespread use. Aspergillus sinusitis in patients with HIV or AIDS occurs in both those with and without traditional risk factors. Fungal sinusitis may present vexing management problems and be relentlessly progressive in the face of therapy. Ideal therapy has yet to be defined but an early combined surgical and medical approach in these compromised patients is preferred.
A comparative randomized study of paravertebral block versus wound infiltration of bupivacaine in modified radical mastectomy

Background: Paravertebral block (PVB) has the potential to offer long-lasting pain relief because it can uniquely eliminate cortical responses to thoracic dermatomal stimulation. Benefits include a reduction in postoperative nausea and vomiting (PONV), prolonged postoperative pain relief, and potential for ambulatory discharge. Aims: To compare PVB with local infiltration for postoperative analgesia following modified radical mastectomy (MRM). Methods: Forty patients undergoing MRM with axillary dissection were randomly allocated into two groups. Following induction of general anesthesia in group P, a catheter was inserted in the paravertebral space and 0.3 ml/kg of 0.25 % of bupivacaine was administered followed by continuous infusion, while in group L, the surgical incision was infiltrated with 0.3 ml/kg of 0.25 % bupivacaine. Statistical Analysis: The statistical tests were applied as unpaired student ‘t’ test/nonparametric test Wilcoxon Mann Whitney test for comparing different parameters such as VAS score and consumption of drugs. The categorical variables such as nausea and vomiting scores, sedation score, and patient satisfaction score were computed by Chi square test/Fisher exact test. Results: VAS score was significantly lower in group P than in group L throughout the postoperative period. The mean alertness score (i.e., less sedation) was higher in group P in the postoperative period than group L. The incidence of PONV was less in PVB group. Conclusion: PVB at the end of the surgery results in better postoperative analgesia, lesser incidence of PONV, and better alertness score.
Association Between Red Blood Cell Distribution Width and COVID-19 Severity in Delta Variant SARS-CoV-2 Infection

Studies have discovered that wild-type SARS-CoV-2 infections are commonly linked to abnormalities in the hematological profiles of COVID-19 patients, one such abnormality being characterized by elevations in red blood cell distribution width (RDW). Whether this linkage reoccurs in delta variant SARS-CoV-2 infection remains unexamined. Here we compared baseline blood parameters in COVID-19 patients infected by wild type and its delta variant, respectively. Our results here point to that although the delta variant has shown increased virulence, transmissibility, and vaccine escape, it has a minimally negative impact on RDW values that were previously found prognostic for COVID-19 severity.
Are Mutual Funds Active Voters?

Mutual funds vary greatly in their reliance on proxy advisory recommendations. Over 25% of funds rely almost entirely on Institutional Shareholder Services (ISS) recommendations, while other funds place little weight on them. Funds with higher benefits and lower costs of researching the items up for vote are less likely to rely on ISS. These actively voting funds are less likely to vote in a "one-size-fits-all" manner, and they earn higher alphas, consistent with benefits from this allocation of resources. For the underlying firms, the presence of actively voting funds mitigates the influence of ISS and helps sway shareholder votes toward value-maximizing outcomes.