Miracle-dz/UniFAR-FTUs huggingface dataset:
The Role of Tissue Oxygen Tension in Dengue Virus Replication

Low oxygen tension exerts a profound effect on the replication of several DNA and RNA viruses. In vitro propagation of Dengue virus (DENV) has been conventionally studied under atmospheric oxygen levels despite that in vivo, the tissue microenvironment is hypoxic. Here, we compared the efficiency of DENV replication in liver cells, monocytes, and epithelial cells under hypoxic and normoxic conditions, investigated the ability of DENV to induce a hypoxia response and metabolic reprogramming and determined the underlying molecular mechanism. In DENV-infected cells, hypoxia had no effect on virus entry and RNA translation, but enhanced RNA replication. Overexpression and silencing approaches as well as chemical inhibition and energy substrate exchanging experiments showed that hypoxia-mediated enhancement of DENV replication depends on the activation of the key metabolic regulators hypoxia-inducible factors 1α/2α (HIF-1α/2α) and the serine/threonine kinase AKT. Enhanced RNA replication correlates directly with an increase in anaerobic glycolysis producing elevated ATP levels. Additionally, DENV activates HIF and anaerobic glycolysis markers. Finally, reactive oxygen species were shown to contribute, at least in part through HIF, both to the hypoxia-mediated increase of DENV replication and to virus-induced hypoxic reprogramming. These suggest that DENV manipulates hypoxia response and oxygen-dependent metabolic reprogramming for efficient viral replication.
Calpionellid biostratigraphy, U-Pb geochronology and microfacies of the Upper Jurassic-Lower Cretaceous Pimienta Formation (Tamazunchale, San Luis Potosí, central-eastern Mexico)

Detailed sampling of a stratigraphic section corresponding to the La Pimienta Formation in the state of San Luis Potosi allows the determination of the upper Tithonian Crassicollaria Zone (Remanei, Brevis and Colomi Subzones). The presence of Praetintinnopsella andrusovi Borza and chitinoidellids in the Crassicollaria Zone, was interpreted as the result of sedimentary reworking as due to fact that these taxa have not been reported in such a high stratigraphic position. Nonetheless additional work is needed in order to establish a clear relationship. The U-Pb date for a bentonite bed that underlies rocks of the Elliptica Subzone is 139.1 ± 2.6 Ma (late Berriasian-early Valanginian). These new data suggest a different age range for the Elliptica Subzone in Mexico as compared with coeval sections in the Mediterranean Tethys.
Replacing IFRS instead of Iranian accounting standard

Accounting standards, are rules governing how to do accounting work, and specify what information must be provided in financial reporting. The main objective of this study was to compare the stronger accounting standards against weaker accounting standards which in this study, we compare accounting standards of Iran and international standard in terms of Rents. The population of the research is institutions member of accounting community; that to collect theoretical principles of the study, library methods and to collect statistical information, questionnaires were used. Cronbach's alpha coefficient was used for validity and reliability of questionnaire, and to analyse the data, Student's t-test, Kolmogorov - Smirnov test and Friedman test was used. SPSS21software was used to analysis. Time limit of this research involves the second half of 2016. The population of the investigation includes audit firms of Certified Public Accountants community. Findings from analysis of statistical data are at 95% reliability level, which reject us hypothesizes based on non-reliability, unsuitability and lack of understanding. We conclude that Iran's accounting standards relative to international standards from the perspective of professional judgment of auditors to determine the rent type, in terms of degree of reliability, intelligibility, functionality is more appropriate.
Using GNIR and RNIR Extracted by Digital Images to Detect Different Levels of Nitrogen in Corn

This study aimed to evaluate the use of vegetation indices, GNIR and RNIR extracted from digital images and using a spectroradiometer in the adjustment models for discrimination nitrogen levels in corn, evaluate the contents and their relationship with corn production components. The experiment was established in a greenhouse with a corn plant per pot in DIC with 5 treatments (0, 50, 100, 200 and 300 kg haG of nitrogen) and 10 repetitions. Evaluations were performed at 15, 30, 45, 60 and 80 DAE, with capturing images using the 720 nm-IR filters, 850 nm-IR and UV-IR cut in a digital camera Fujifilm IS Pro and spectroradiometer readings were used the Spring and Excel software to calculate GNIR and RNIR vegetation indices. The GNIR showed higher sensitivity for assessment of nitrogen deficiency in maize. The use of camera appeared as a promising tool for nitrogen discrimination. The use 720 nm filter was higher to 850 nm. The best times to break down the nitrogen doses evaluated by vegetation indices were 60 and 80 DAE.
Group Counselling with Systematic Desensitization and Emotional Freedom Techniques to Reduce Public Speaking Anxiety

Public Speaking or the ability to speak in public is one of basic competencies that must be owned by students. However, apparently, there found many students having public speaking anxiety and in high category. Regarding this problem, this study was aimed at examining the effectiveness of a group counselling with desensitization technique and emotional freedom technique in reducing students' public speaking anxiety. The implementation of those techniques were done twice in each group counselling service. Meanwhile, the research method employed was mixed anova repeated measures test design by involving 16 students having high level public anxiety chosen from 100 students by using purposive sampling. Further, the results of mixed anova repeated measure showed thatthe group counselling with systematic desensitization technique and emotional freedom technique (EFT) was proved to be effective in reducing the public speaking anxiety of students. Besides, seen from the average score and time effect, emotional freedom technique resulted higher decrease than systematic desensitization technique. For more, the more emotional freedom technique was given, the higher decrease of the public speaking anxiety of students would result.
Teacher Education and Development in Nigeria: An Analysis of Reforms, Challenges and Prospects

Although teacher education, both pre-and in-service, programs are offered in Nigeria by different teacher education institutions (as provided in the National Policy on Education), and varying degrees of success recorded, various problems still confront the program with far reaching consequences in Nigeria’s educational system. This paper talks about the need for teacher education, the ideal teacher education, teacher education and national development, analyses the historical contexts of the teacher education reforms and development in Nigeria with emphasis on the roles of the Christian missions, the colonial administration and that of the Nigerian government after independence. It examines key recommendations of two commissions (Phelps Stokes and Ashby) and their implications to the reform and development of teacher education in Nigeria both during colonial era and after independence. The paper further discusses the influence of these and other reforms in shaping teacher education in Nigeria, the challenges still facing it, and finally suggests solutions and a holistic approach to better the lots of teacher education in Nigeria.
CONVERGENCE OF FORMAL SOLUTIONS OF SINGULAR FIRST ORDER NONLINEAR PARTIAL DIFFERENTIAL EQUATIONS OF TOTALLY CHARACTERISTIC TYPE (Integral representations and twisted cohomology in the theory of differential equations)

CONVERGENCE OF FORMAL SOLUTIONS OF SINGULAR FIRST ORDER NONLINEAR PARTIAL DIFFERENTIAL EQUATIONS OF TOTALLY CHARACTERISTIC TYPE (Integral representations and twisted cohomology in the theory of differential equations) Author(s) Shirai, Akira Citation 数理解析研究所講究録 (2001), 1212: 116-132 Issue Date 2001-06 URL http://hdl.handle. net/2433/41152 Right Type Departmental Bulletin Paper Textversion publisher
Probiotic activity of Pseudomonas aeruginosa (PIC-4) isolated from Visakhapatnam coast, Bay of Bengal, India, against Vibrio harveyi in Penaeus monodon

Pseudomonas aeruginosa (PIC 4), isolated from coastal waters of Visakhapatnam (Gen Bank Accession no: KF803248) was tested for its antagonistic activity against Vibrio harveyi as probiotic in cultured Penaeus monodon. Pseudomonas aeruginosa PIC 4 has proved to be non-pathogenic to the shrimp by pathogenicity tests. Vibrio counts in probiotic fed shrimp and the surrounding water medium were significantly lower when compared to the control group of shrimp and water during 50 days of culture. Mean weight of probiont fed shrimps after 50 days of culture was (2.21 + 0.15 g) , significantly higher than that of normal diet fed ones (1.33+0.18 g). Survival percent was also significantly higher in probiont fed shrimp (47.33% + 5.55%) than that of the control diet fed shrimp (26.33% + 7%). Percent survival in probiotic fed and normal diet fed shrimp after the challenge with V. harveyi was 93.04 and 38.87 respectively.
RELATIVE EFFECTS OF WARM-LIP WITH UNDERWEIGHT, OVERWEIGHT, AND STANDARD WEIGHT BATS ON BAT VELOCITY AND SEGMENTAL MOVEMENT

The purpose of this investigation was to compare the effects of warming up with bats of varying weight on pre-impact bat linear velocity and on the timing and extent of segmental movement during the baseball swing, Sixteen varsity high school baseball players volunteered as subjects for the study The subjects were videotaped from overhead while hitting wiffle balls off of a hitting tee following each of three standardized warm-up routines using bats of varying weight Each subject performed 6-10 swings following each warm-up condition with the three best swings per condition selected for analysis, Pre-impact velocity of the impact point of the bat (measured electronically) and the timing and extent of segmental movements were compared, No significant intergroup differences for either pre-impact bat linear velocity or the segmental kinematic variables were found,
An Empirical Examination of the Relationships between Service Quality, Satisfaction and Behavioral Intentions in Higher Education Setting

The main aim of this study is to examine the relationship between service quality and customer satisfaction and their impact on behavioral intentions in higher education setting in Serbia. Two competing models, revealed during the literature review, have been tested on a sample of Engineering Management students by means of structural equation modeling, performed via LISREL 8. Results of the study indicate that satisfaction is influenced by service quality and directly related to behavioral intentions, thus offering support for Oliver’s (1999) cognition-affect-conation sequence of causal relationships in loyalty formation. Implications of the study have been discussed and limitations and directions for future research are outlined.
Utilization of Audio Visual Media to Improve Student Learning Result in IPS Learning

This study is motivated by the low learning outcomes of students in social studies in class VII C SMP Negeri 7 Bandung. The purpose of this study is to describe the planning, implementation, results, constraints and efforts to improve student learning outcomes. This research uses PTK with Kemmis model and MC Taggart by using audio visual media in learning. The subject of this study is the students of class VII C SMP Negeri 7 Bandung as many as 40 students. Planning of this research include preparing RPP and make research instrument according to the needs of researchers. This study was conducted for three cycles and obtained the improvement of student learning outcomes in the IPS lesson from first cycle until the third cycle. Student learning outcomes on one cycle obtained indigo with sufficient criteria, in the second cycle obtained the value with good criteria, and the third cycle obtained the value with very good criteria. The increase is one of them is marked by student learning outcomes that are above the KKM. Constraints of this research is one of the difficulty to revise the learning video that there is some negative content and adjust it with RPP. These constraints can be overcome by removing part of the negative content by editing and searching for videos from a trusted source. This research uses qualitative and quantitative data analysis.
Tolerance of common bean (Phaseolus vulgaris L.) to different durations of simulated shallow water table condition

Shallow water table problem has lessened farmer’s interest in cultivating vegetables at riparian wetland in Indonesia. At present, riparian wetlands are mostly underutilized. Objective of this study was to evaluate tolerance of common bean (Phaseolus vulgaris) to shallow water table condition. Common bean variety of PV072 was used in this study. Research was conducted in Jakabaring, South Sumatra, Indonesia; from November 2016 to February 2017. Leaf and root growth or damage can be used as an indicator of stress tolerance in plants exposed to unfavorable soil conditions. Results of our study indicated that roots of common bean were unable to survive in water saturated condition below water table, but the plants were able to compensate for this constraint by increasing root biomass within aerobic substrate above water table. Moreover, after termination of shallow water table treatment, common bean was able to regrow their roots into the ex-saturated zone. Common bean plants produced marketable yield albeit limited rhizosphere space. Interestingly, the plants exposed to 24 days of shallow water table produced the highest yield. In conclusion, common bean can be considered as tolerant vegetable to shallow water table. It should be noted that bean leaf reached 90 percent and full size in less than 6 days and 9 days, respectively, after the young leaf was unfolded. Therefore, long term study on bean leaf growth and development requires measurement on sequential and multiple leaves. Also, nocturnal relative leaf expansion rate (RLER) was significantly faster than diurnal RLER.
The entrainment-limited evolution of FR II sources: maximum sizes and a possible connection to FR Is

We construct a simple theoretical model to investigate how entrainment gradually erodes high-speed FR II jets. This process is described by embedding a mixing-layer model developed originally to describe FR I objects in a self-similar model for the lobe structure of classical FR II sources. Following the classical FR II models, we assume that the lobe is dominated by the particles injected from the central jet. The entrainment produces a boundary shear layer which acts at the interface between the dense central jet and the less denser surrounding lobe, and the associated erosion of the jet places interesting limits on the maximum size of FR II sources. The model shows that this limit depends mainly on the initial bulk velocity of the relativistic jet triggered. The bulk velocities of FR IIs suggested by our model are in good agreement with that obtained from direct pc-scale observations on ordinary radio galaxies and quasars. Finally, we discuss how FR IIs may evolve into FR Is upon reaching their maximum, entrainment-limited sizes.
Combining inflation-free and iterative ensemble Kalman filters for strongly nonlinear systems

Abstract. The finite-size ensemble Kalman filter (EnKF-N) is an ensemble Kalman filter (EnKF) which, in perfect model condition, does not require inflation because it partially accounts for the ensemble sampling errors. For the Lorenz '63 and '95 toy-models, it was so far shown to perform as well or better than the EnKF with an optimally tuned inflation. The iterative ensemble Kalman filter (IEnKF) is an EnKF which was shown to perform much better than the EnKF in strongly nonlinear conditions, such as with the Lorenz '63 and '95 models, at the cost of iteratively updating the trajectories of the ensemble members. This article aims at further exploring the two filters and at combining both into an EnKF that does not require inflation in perfect model condition, and which is as efficient as the IEnKF in very nonlinear conditions. In this study, EnKF-N is first introduced and a new implementation is developed. It decomposes EnKF-N into a cheap two-step algorithm that amounts to computing an optimal inflation factor. This offers a justification of the use of the inflation technique in the traditional EnKF and why it can often be efficient. Secondly, the IEnKF is introduced following a new implementation based on the Levenberg-Marquardt optimisation algorithm. Then, the two approaches are combined to obtain the finite-size iterative ensemble Kalman filter (IEnKF-N). Several numerical experiments are performed on IEnKF-N with the Lorenz '95 model. These experiments demonstrate its numerical efficiency as well as its performance that offer, at least, the best of both filters. We have also selected a demanding case based on the Lorenz '63 model that points to ways to improve the finite-size ensemble Kalman filters. Eventually, IEnKF-N could be seen as the first brick of an efficient ensemble Kalman smoother for strongly nonlinear systems.
Adipocyte browning and higher mitochondrial function in peri-adrenal but not subcutaneous fat in pheochromocytoma. Journal of Clinical Endocrinology and Metabolism, 101 (11). pp.

Context: Patients with pheochromocytoma (pheo) show presence of multilocular adipocytes that 38 express uncoupling protein (UCP) 1 within periadrenal (pADR) and omental (OME) fat depots. It 39 has been hypothesized that this is due to adrenergic stimulation by catecholamines produced by 40 the pheo tumors. 41 Objective: To characterize the prevalence and respiratory activity of brown-like adipocytes 42 within pADR, OME and subcutaneous (SC) fat depots in human adult pheo patients. 43 Design: This was an observational cohort study. 44 Setting: University hospital. 45 Patients: We studied 46 patients who underwent surgery for benign adrenal tumors (21pheos and 46 25 controls with adrenocortical adenomas). 47 Main outcome measure: We characterized adipocyte browning in pADR, SC, and OME fat 48 depots for histological and immunohistological features, mitochondrial respiration rate, and gene 49 expression. We also determined circulating levels of catecholamines and other browning-related 50 hormones. Results: 11 of 21 pheo pADR adipose samples, but only 1 of 25 pADR samples from control 52 patients, exhibited multilocular adipocytes. The pADR browning phenotype was associated with 53 higher plasma catecholamines and raised UCP1. Mitochondria from multilocular pADR fat of 54 pheo patients exhibited increased rates of coupled and uncoupled respiration. Global gene expression analysis in pADR fat revealed enrichment in  -oxidation genes in pheo patients with 56 multilocular adipocytes. No SC or OME fat depots exhibited aspects of 57 Conclusion: Browning of the pADR depot occurred in half of pheo patients and was 58 with increased catecholamines and mitochondrial activity. No browning was detected in other 59 depots, suggesting that other factors are required to promote browning in these
Investigating Occupational Commitment and Turnover Intention Relationship with Burnout Syndrome

This study investigates burnout components impact on accountant’s occupational commitment and occupational turnover intention interaction. The data used in this study was taken from randomly selected 162 accountants who are the members of Istanbul Chambers of Certified Public Accountants (ICCPA). The results reveal that only emotional exhaustion component of burnout has partial mediating effect between affective occupational commitment and occupational turnover intention.
Diel behaviour and habitat utilisation by the pearly razorfish during the spawning season

Despite its small size, the pearly razorfish Xyrichtys novacula (Linnaeus, 1758) supports important targeted recreational and commercial fisheries. Here, we present the first data on the movements of this species obtained using acoustic telemetry in a temperate marine protected area (MPA). The results demonstrate that acoustic telemetry is well suited for behavioural studies, even in species of small size. The results confirmed previous speculations regarding the behaviour of this species, demonstrating a clear diel pattern with maximum rates of activity during the day and fewer detections at night, when the fish bury themselves in the soft bottom. X. novacula exhibited a sedentary lifestyle with limited movement. The fish occurred in an accumulated averaged area of 0.32 ± 0.13 km2 95% of the time (95% kernel utilisation distribution [KUD]) and in a core area (50% KUD) of 0.07 ± 0.02 km2. These small areas of habitat utilisation existed independent of sex and diel behaviour. No daily migration pattern or specific resting locations were detected. The linearity index (as a proxy of site fidelity) demonstrated that the movement of X. novacula was random within a specific home range area (sedentary behaviour) rather than directional (nomadic behaviour). The observed diel pattern of behaviour confirms that this species is not vulnerable to nighttime fishing, and the small spatial scale of habitat utilisation suggests that small MPAs can be an effective management tool.
A SEARCH FOR NEW CANDIDATE SUPER-CHANDRASEKHAR-MASS TYPE Ia SUPERNOVAE IN THE NEARBY SUPERNOVA FACTORY DATA SET

We present optical photometry and spectroscopy of five Type Ia supernovae discovered by the Nearby Supernova Factory selected to be spectroscopic analogs of the candidate super-Chandrasekhar-mass events SN 2003fg and SN 2007if. Their spectra are characterized by hot, highly ionized photospheres near maximum light, for which SN 1991T supplies the best phase coverage among available close spectral templates. Like SN 2007if, these supernovae are overluminous (−19.5 < MV < −20) and the velocity of the Si ii λ6355 absorption minimum is consistent with being constant in time from phases as early as a week before, and up to two weeks after, B-band maximum light. We interpret the velocity plateaus as evidence for a reverse-shock shell in the ejecta formed by interaction at early times with a compact envelope of surrounding material, as might be expected for SNe resulting from the mergers of two white dwarfs. We use the bolometric light curves and line velocity evolution of these SNe to estimate important parameters of the progenitor systems, including 56Ni mass, total progenitor mass, and masses of shells and surrounding carbon/oxygen envelopes. We find that the reconstructed total progenitor mass distribution of the events (including SN 2007if) is bounded from below by the Chandrasekhar mass, with SN 2007if being the most massive. We discuss the relationship of these events to the emerging class of super-Chandrasekhar-mass SNe Ia, estimate the relative rates, compare the mass distribution to that expected for double-degenerate SN Ia progenitors from population synthesis, and consider implications for future cosmological Hubble diagrams.
Capital Gains Taxation and Stock Market Investments: Empirical Evidence

The objective of this study is to examine stock market investments responses to changes in capital gains tax rate. A priori, rational taxpayers are expected to respond to changes in this tax rate. For example, a reduction (increase) in capital gains tax rates may make taxpayers to unlock (lock-in) substantial amounts of accrued (realizable) appreciated gains. The findings of this study however reveal that capital gains realization and not capital gains tax rates impacts stock market investments in the U.S.