Miracle-dz/UniFAR-FTUs huggingface dataset:
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders.

OBJECTIVE This study was designed to determine the effectiveness of a group stress reduction program based on mindfulness meditation for patients with anxiety disorders. METHOD The 22 study participants were screened with a structured clinical interview and found to meet the DSM-III-R criteria for generalized anxiety disorder or panic disorder with or without agoraphobia. Assessments, including self-ratings and therapists' ratings, were obtained weekly before and during the meditation-based stress reduction and relaxation program and monthly during the 3-month follow-up period. RESULTS Repeated measures analyses of variance documented significant reductions in anxiety and depression scores after treatment for 20 of the subjects--changes that were maintained at follow-up. The number of subjects experiencing panic symptoms was also substantially reduced. A comparison of the study subjects with a group of nonstudy participants in the program who met the initial screening criteria for entry into the study showed that both groups achieved similar reductions in anxiety scores on the SCL-90-R and on the Medical Symptom Checklist, suggesting generalizability of the study findings. CONCLUSIONS A group mindfulness meditation training program can effectively reduce symptoms of anxiety and panic and can help maintain these reductions in patients with generalized anxiety disorder, panic disorder, or panic disorder with agoraphobia.
THE INVESTIGATION OF PARTICULATE CORROSION PRODUCT DEPOSITION ON HEAT TRANSFER SURFACES : A COMPARISON OF EXPERIMENTS AND THEORY AND A PRELIMINARY STUDY OF THE REMOVAL MECHANISM

The research program at the University of New Brunswick (UNB) into the fouling of heat exchangers in cooling water systems began in the early 1990s. Since then, experiments and numerical simulations (using the fluid dynamics codes PHOENICS and FLUENT 4.5) have investigated the deposition of oxide particles suspended in water at atmospheric pressure onto heated surfaces. This paper summarizes the program and tests the mathematical model that was proposed in 2007 against the experimental results. The experiments were carried out under isothermal conditions and various modes of heat transfer: non-boiling, subcooled boiling and bulk boiling. Sub-micrometre particles of iron oxides (magnetite and nickel ferrite) were synthesized and added to a recirculating loop, where their deposition from suspension along an Alloy-800 tube at a heat flux up to 240 kW/m was studied. The mathematical model considers deposition and concomitant removal of particles and consolidation of deposits as a comprehensive deposition mechanism under transport-controlled conditions. It indicates that size, nucleation frequency and nucleation site geometry of bubbles play an important rôle in the global deposition flux. Predictions of the model are in general agreement with the experimental results. Recently, the mechanisms have been tested experimentally under conditions favouring attachment control rather than transport control. Similar results were obtained for deposition but not for removal.
Solitary Mastocytoma Improved by Intralesional Injections of Steroid

Solitary mastocytoma is an uncommon disease characterized by monotonous infiltrations of mast cells that extend from papillary dermis to subcutaneous fat. They usually resolve by adulthood, and there is no satisfactory treatment other than waiting. A two‐month‐old Korean male infant with deep solitary mastocytoma was treated intralesionally with triamcinolone acetonide. His mastocytoma in medial malleolus was very distressing because it was very sensitive to friction, and he was just reaching the crawling stage. After three injections, his skin lesion flattened with marked decrease of erythema and subjective symptoms. His skin lesion has continued to have a good clinical response for 9 months after the last treatment.
Prospective Case Series of a Novel Minimally Invasive Bipolar Coagulation System in the Treatment of Grade I and II Internal Hemorrhoids

Background. Existing nonsurgical procedures for the treatment of grade I and II internal hemorrhoids are often painful, technically demanding, and often necessitate multiple applications. This study prospectively assessed the safety and efficacy of the HET Bipolar System, a novel minimally invasive device, in the treatment of symptomatic grade I and II internal hemorrhoids. Methods. Patients with symptomatic grade I or II internal hemorrhoids despite medical management underwent hemorrhoidal ligation with the HET Bipolar System. Endpoints included resolution or improvement of hemorrhoidal bleeding and/or prolapse from baseline, recurrent or refractory symptoms, and pain. Results. Twenty patients were treated with the HET Bipolar System. Two were lost to follow-up. Refractory or recurrent bleeding was present in 8 of 18 (44.4%), 4 of 11 (36.4%), and 4 of 8 (50.0%) patients, and prolapse was reported by 1 of 18 (5.6%), 4 of 11 (36.4%), and 1/7 (14.3%) of patients at 1, 3, and 6 months, respectively. Bleeding improved from baseline in 88.2%, 81.8%, and 87.5% of patients, and resolution of baseline prolapse was seen in 11 of 11 (100%), 4 of 7 (57.1%), and 5 of 5 (100%) patients at the same intervals. Thirteen of 18 (72.2%) patients did not require additional treatment for their symptoms. Conclusions. The HET Bipolar System is safe and easy to use with short-term effectiveness comparable to that of currently used techniques for the treatment of symptomatic grade I and II internal hemorrhoids. It may be an effective alternative to rubber band ligation in patients with larger internal hemorrhoids and those with hemorrhoids close to the dentate line in which banding may produce debilitating pain.
Comparison of ‘pattern recognition’ and logistic regression models for discrimination between benign and malignant pelvic masses: a prospective cross validation

To test prospectively the diagnostic performance of two logistic regression models for calculation of individual risk of malignancy in adnexal tumors (the ‘Tailor model’ and the ‘Timmerman model’), and to compare them to that of ‘pattern recognition’ (subjective evaluation of the gray‐scale ultrasound image and color Doppler ultrasound examination).
Scale of Positive and Negative Aﬀ ects (EAPN-10): Evidence of its Psychometric Adequacy

This study aimed to gather psychometric evidence of the Scale of Positive and Negative Aff ects (EAPN10) within the Brazilian context. Three studies were performed (N = 911). Study 1 considered 296 undergraduate students (MAge = 23.8; 59.1% females), who answered the EAPN-10 and a demographic questionnaire. Exploratory factor analysis revealed a two-factor structure [positive aff ects (α = .82) and negative aff ects (α = .81)], explaining 59.7% of the total variance. Study 2 took into account the participation of 313 undergraduate students (MAge = 23.3; 57.2% females), who answered the same instruments. Confi rmatory factor analysis corroborated the two-factor structure (e.g., CFI = .92), which was invariant across males and females (e.g., ΔCFI < .01), with alphas greater than . 70. Finally, Study 3’s participants were 302 university students (MAge = 23.1; 54.3% females), who answered the aforementioned instruments as well as measures of vitality, positivity, optimism, anxiety, depression and stress. Supporting their criterion validity, positive aff ects (α = .83) were positively correlated Gouveia, V. V. , Ribeiro, M. G. C. , Loureto, G. D. L. , Silva Neta, O. F. , Gouveia, R. S. V. , Vilar, R. , Freire, S. E. A. 190 Trends Psychol. , Ribeirão Preto, vol. 27, no 1, p. 189-203 March/2019 with well-being indicators, and negative aff ects (α = .80) were positively correlated with indicators of psychological discomfort. In conclusion, the EAPN-10 is a psychometrically adequate measure that can be employed to assess people’s aff ects and their correlates within the Brazilian context.
Richness of bryophyte vegetation in near-natural and managed beech stands : the effects of management-induced differences in dead wood

Natural forests have a fundamentally different disturbance regime than managed forests, consequently their stand structures are also different (West et al. 1981, Pickett and White 1985, Tyrell and Crow 1994, Peterken 1996, Oliver and Larson 1996, Kuuluvainen et al. 1996, Parminter 1998). This is especially true under those circumstances where a clear cutting system is applied in forests where a natural disturbance regime is dominated by single tree based or small gap dynamics, like in moist deciduous temperate forests (Runkle 1985). In natural forests, gap formaRichness of bryophyte vegetation in near-natural and managed beech stands: the effects of management-induced differences in dead wood
Perceptions of NPs and administrators in regard to the governing and supervision of NPs in Taiwan

Purpose: To determine the perceptions of nurse practitioners (NPs) and administrators in regard to the governing and supervision of NPs, using a qualitative approach. Data sources: The study used a qualitative research design, with 14 participants recruited through purposive sampling. Data were collected through a semi‐structured interview and were analyzed through content analysis to identify the concepts and themes. Conclusions: NPs in Taiwan are challenged by a number of barriers; however, they remain positive that their circumstances will improve. Implications for practice: The results indicated that clinicians and hospital managers, including NPs themselves, need to have a solid understanding of NP regulations. Communication with other disciplines and policymakers is key to success in the NP role. This study provides valuable information for NPs, other healthcare professionals, and administrators in terms of promoting the role of NPs.
Assessment of Technical and Socioeconomical Feeding Practices in Semiarid and Arid Areas in North India (Haryana), and Implications for Dairy Rural Development

Since the end of the 1990s, India has become the world first producer of milk, before the United State, with a production close to 74 million tons in 1998 [92 million in 2004 (13)]. Over the period 1973-1995, the average daily availability of milk per inhabitant increased from 112 g (1973-74) to 194 (1994-95)**. This performance is partially the result of Operation Floods, launched by the National Dairy Development Board (NDDB) in the 1970s. NDDB has been created and managed by Dr Kurien since 1970-71, after the success of the Kheda District Cooperative Milk Producers’ Union in Gujarat State where farmers decided to sell milk themselves and bypassed middlemen. Today NDDB counts more than 9.7 millions of producers and 75,000 societies at the village level. NDDB is in charge of collecting and transforming milk, and ensures different services to the farmers (veterinary and social services, feed supply or advice, etc.). This is the achievement of numerous technical and organizational efforts to tap a scattered supply system and make the product accessible to the urban population. These achievements have been obtained on farms that register very low animal performance.
SEARCHING FOR AN ALTERNATIWE WAY TO MANAGE

The perlormance of ‘Grasslands Matua’ prairie grass was compared under lax and hard grazing by sheep Pasture utilisatlon and bller densltres were measured to determme If l”cremng utllsatlon would result I” sward decline Lax grazmg permitted ward persistence but resulted m only 56% pasture utilisatlon Hard grazmg at 75% pasture ut! llsatlon resulted m less total herbage harvested, owng prlmar~ly to ward decline. Nevertheless, of was shown that hard grazmg can mprove pasture utlllsation wthout affectmg ward persistence of grazmg 1s delayed until new replacement tillers have appeared This allows slgnlflcanlly greater pasture utll1satlon than lax grar! ng and mamtains prawe grass tiller density,
Cetuximab, Paclitaxel, Carboplatin, and Radiation for Head and Neck Cancer: A Survival Analysis of a Brown University Oncology Group Phase II Study

Objectives:To assess the effect on progression-free and overall survival from the addition of cetuximab to paclitaxel-based chemoradiation for patients with squamous cell head and neck cancer from Brown University Oncology Group studies. Methods:BrUOG HN-204 patients with stage III or IV locally advanced squamous cell cancer of the head and neck without distant organ metastases received 4 weeks of induction cetuximab followed by weekly cetuximab, paclitaxel, carboplatin, and concurrent radiation. Recurrence and survival data were compared with previous Brown University studies utilizing the same paclitaxel-based chemoradiation with and without induction chemotherapy. Results:The progression-free survival and overall survival at 3 years for all 37 patients initiating chemoradiation was 54% and 57%, respectively. All surviving patients were followed for at least 3 years and the median follow-up is 4.4 years. Of 14 patients who recurred within 3 years, 7 patients recurred locally only, 5 had a systemic recurrence, and 2 recurred both locally and systemically. Conclusions:The addition of cetuximab to paclitaxel, carboplatin, and radiation achieves overall survival that is virtually identical to prior Brown University Oncology Group studies of paclitaxel-based chemoradiation without cetuximab. Improvements in locoregional control are needed despite the use of 3 agents to enhance the effects of radiation.
Herpes Zoster in Juvenile-Onset Systemic Lupus Erythematosus: Incidence, Clinical Characteristics and Risk Factors

Background: Herpes zoster (HZ) is common in systemic lupus erythematosus (SLE) patients, but its clinical features and risk factors in juvenile-onset SLE have not been well described before. Methods: A retrospective review of the clinical course and infections in pediatric SLE patients managed in our institution from 1988–2004 was performed. Clinical characteristics and potential risk factors for HZ were analyzed. Results: Forty-nine children with SLE were identified. Nineteen episodes of HZ were recorded in 15 patients, and 2 of them had recurrent HZ. The incidence rate was 58.7 episodes/1000 patient-years. No patient had disseminated HZ, postherpetic neuralgia, or cutaneous scarring, and no death was attributed to HZ. Most (63.2%) HZ occurred within 6 months from onset of SLE or disease flare-up. There was no significant difference in age of onset of SLE, gender, disease duration, use of high dose steroid, or other immunosuppressive agents in patients with and without HZ. Patients with HZ were more likely to have prior or concurrent lupus nephritis (86.7%) than those without HZ (58.5%) (P = 0.096). Occurrence of other major infections was also significantly more common in those who had HZ (80.0%) than those without (32.3%) (P = 0.006). Conclusions: Herpes zoster was common in juvenile-onset SLE patients. Most were benign, without systemic dissemination and postherpetic neuralgia. SLE patients with renal involvement and heightened lupus activity were at greater risk of having HZ. Those with HZ were also more likely to have other major infections during their disease course.
Residential cognitive-behavioral weight-loss intervention for obesity with and without binge-eating disorder: A prospective case-control study with five-year follow-up.

OBJECTIVE The aim of this prospective case-control study was to compare the long-term effects of a residential cognitive-behavioral treatment (CBT) for weight loss in severely obese patients with and without binge-eating disorder (BED). METHODS We assessed weight-loss outcomes and psychological impairment in 54 severely obese female patients with BED and 54 patients matched by age, gender, and body mass index (BMI) without BED admitted to a residential CBT program. Body weight was measured at baseline and at 6-month follow-up and was reported by patients in a telephone interview at 5-year follow-up. Depression, eating disorder psychopathology, general psychopathology, and quality of life were assessed using validated instruments at baseline and at 6-month follow-up. RESULTS Obese patients with and without BED had similar weight loss at 6-month and 5-year follow-ups. Although both groups showed improved psychosocial variables, at 6 months the BED group maintained higher psychological impairment. Nevertheless, at 5-year follow-up more than half of the BED participants were no longer classifiable as having BED. DISCUSSION The presence of BED does not affect weight-loss outcome in obese patients treated with the residential CBT for weight loss program considered. © 2016 Wiley Periodicals, Inc.(Int J Eat Disord 2016; 49:723-730).
RIGOTRIO at SemEval-2017 Task 9: Combining Machine Learning and Grammar Engineering for AMR Parsing and Generation

By addressing both text-to-AMR parsing and AMR-to-text generation, SemEval-2017 Task 9 established AMR as a powerful semantic interlingua. We strengthen the interlingual aspect of AMR by applying the multilingual Grammatical Framework (GF) for AMR-to-text generation. Our current rule-based GF approach completely covered only 12.3% of the test AMRs, therefore we combined it with state-of-the-art JAMR Generator to see if the combination increases or decreases the overall performance. The combined system achieved the automatic BLEU score of 18.82 and the human Trueskill score of 107.2, to be compared to the plain JAMR Generator results. As for AMR parsing, we added NER extensions to our SemEval-2016 general-domain AMR parser to handle the biomedical genre, rich in organic compound names, achieving Smatch F1=54.0%.
Relationship between quality of life and functional status of young adults and adults with cerebral palsy

Purpose. The aim of this study was investigate the relation between health related quality of life (HRQoL) and functional status in young adult or adult cerebral palsied individuals. Methods. The study included 45 cerebral palsied subjects who were divided into two groups as young adults (n = 21, group 1) and adults (n = 24, group 2), over the age 15 years. Gross Motor Function Classification System (GMFCS), Functional Independence Measurement (FIM), Physical Mobility Scale (PMS), Nottingham Health Profile (NHP), Visual Analogue Scale (VAS) were used as outcome measures. Results. In group 1, GMFCS and PMS scores were significantly correlated with total the total score of FIM (p < 0.05). Although total FIM, PMS, LS and GMFCS scores were not correlated with the total NHP score (p > 0.05), pain subscale of NHP was significantly correlated with self care and mobility subscales of FIM (p < 0.05). Also, self care, mobility, locomotion subscales and total score of FIM were highly correlated with the physical activity subscale of NHP (p < 0.05). In group 2, our findings were also similar to those of young adults when the relations between total NHP score and total FIM, PMS, LS and GMFCS were investigated (p > 0.05) and also some subscales of FIM and NHP presented high correlations in between. In addition, there were significant differences between the groups in GMFCS, LS and locomotion and self care subscales of FIM (p < 0.05). Conclusion. Although HRQoL in young cerebral palsied individuals seems to be more effected by parameters related to physical condition, in cerebral palsied adults psychological and emotional aspects may be more important indicators related to HRQoL. For that reasons, more population specific measures have to be developed for in-depth analysis of these factors.
Apoptotic Response to 5-Fluorouracil Treatment Is Mediated by Reduced Polyamines, Non-Autocrine Fas Ligand and Induced Tumor Necrosis Factor Receptor 2

5-fluorouracil (5-FU) is the major chemotherapeutic agent for treatment of colorectal carcinoma, but the molecular mechanisms of response and resistance are not understood completely. We therefore studied the 5-FU dose response and time course of gene expression transcriptome changes in colon carcinoma cell lines that are relatively sensitive or resistant to 5-FU (RKO and HT29, respectively) in order to identify cellular pathways and corroborate functions of selected pathways. Expression of genes for polyamine biosynthesis, i.e. ornithine decarboxylase (ODC) and spermine and spermidine synthases, was repressed in the sensitive line, while the biosynthesis-inhibiting gene ODC antizyme was induced in the resistant line, and the rate-limiting gene in catabolism, spermine/spermidine acetyltransferase, was induced in both lines. Polyamine levels showed corresponding drastic decreases after 5-FU treatment, and polyamine replenishment interfered with 5-FU-induced apoptosis. In the sensitive cells which have wild-type p53, the p53 gene and its downstream genes including p21/WAF1, mdm2, Fas, mic-1, EphA2, and ferredoxin reductase as well as genes in the tumor necrosis factor (TNF) pathway including TNF receptor 2 (TNFR2) were induced, but not Fas ligand (FasL). Exposure to exogenous FasL increased 5-FU-induced apoptosis, and anti-TNFR2 antibody but not anti-TNFR1 partially protected the sensitive cells. Our combination of gene expression profiling and corroborative functional studies revealed that reduced polyamine levels, non-autocrine FasL originating exogenous to tumor cells, and induced TNFR2 are all functional mediators of apoptosis caused by 5-FU in colon carcinoma cells.
Hydrogen peroxide concentration and DNA fragmentation of buffalo oocytes matured in sericin-supplemented maturation medium

This study was conducted to investigate the effects of sericin on meiotic maturation, hydrogen peroxide (H 2 O 2 ) concentration and deoxyribonucleic acid (DNA) fragmentation in buffalo oocytes. Oocytes were matured in vitro in tissue culture medium (TCM199) with in vitro maturation (IVM) groups under several conditions, namely without bovine serum albumin (BSA), (+BSA), and 0.025%, 0.05%, 0.1% and 0.25% (w/v) sericin. The results showed that supplementation of the maturation medium with 0.05% sericin significantly increased the rate of oocytes that reach metaphase II compared with other groups, except for the 0.025% sericintreated group. Intracellular H 2 O 2 concentrations in oocytes of all groups were measured using 2',7'dichlorodihydrofluorescein diacetate (DCHFDA). The concentration of H 2 O 2 in matured oocytes treated with 0.05% sericin was lower than in other groups. DNA fragmentation and the nuclear status of oocytes were examined using the terminal deoxyribonucleotidyl transferase-mediated dUTP digoxigenin nick endlabelling (TUNEL) method. The total proportion of TUNELpositive oocytes at the MII stage was lower in the 0.05% sericin group. The results indicate that addition of 0.05% sericin to the maturation medium may improve nuclear maturation and may inhibit DNA fragmentation in oocytes by decreasing H2O2 concentrations. Keywords: antioxidant, apoptosis, in vitro maturation, reactive oxygen species
Isolation and characterization of expressed sequence tag‐linked microsatellite loci for the European eel (Anguilla anguilla)

A European eel (Anguilla anguilla) expressed sequence tag database consisting of 795 contigs and 4008 singletons was screened for microsatellites sequences. Primers were designed to amplify 96 repeats, of which 86 gave good quality amplification products. Twenty‐eight microsatellites were selected for further microsatellite genotyping. Only two loci were found to be monomorphic; out of the 26 polymorphic loci, number of alleles per locus ranged from two to 14, while the observed and expected heterozygosities ranged from 0.05 to 0.93, and from 0.05 to 0.95, respectively. All 28 primer sets tested revealed positive amplification in American eel (Anguilla rostrata).