Miracle-dz/UniFAR-FTUs huggingface dataset:
Hierarchical Motion Tracking Using Matching of Sparse Features

Fundamental approaches in motion tracking are based on registration of pixel patches from one frame to another. To ensure invariance to some changes in the image and improve the speed of discovering a match, a pyramidal approach is used to steer the process faster to optima. However, registration of the patches in high resolution is still computationally expensive. Because we require the algorithm to process Ultra HD video content in real time on commonly available hardware, especially on mid-tier graphics processing units, approaches using matching of pixel patches are not feasible. In this paper, we present and evaluate an approach inspired by motion tracking on an image pyramid. However, instead of comparing pixel patches one to another, we utilise binary image descriptors that are much shorter and inherently use a Hamming distance for their direct comparison. Evaluation of our implementation, which is available on GitHub, was carried out on the Multiple Object Tracking challenge dataset.
MicroRNA-126 and epidermal growth factor-like domain 7 predict recurrence in patients with colon cancer treated with neoadjuvant chemotherapy

Aim: Neoadjuvant chemotherapy may represent a shift in the treatment of locally advanced colon cancer. The angiogenic couple has-microRNA-126 (miRNA-126) and epidermal growth factor-like domain 7 (EGFL7) are transcribed from the same gene and regulates all aspects of angiogenesis and may influence the ability of tumor cells to disseminate. The aim was to analyze the relationship between miRNA-126 and EGFL7 and disease recurrence in patients with locally advanced colon cancer treated with neoadjuvant chemotherapy. Methods: This study included 71 patients from a phase II study all planned for three cycles of capecitabine and oxaliplatin before surgery. Blood was sampled at baseline and right before and after the operation. Circulating miRNA-126 was analysed by RT-qPCR and a quantitative immunoassay was used for the analyses of EGFL7. Results: The rates of 5-year disease-free survival (DFS) and overall survival (OS) were 80% and 85%, respectively. The level of circulating miRNA-126 before the operation predicts recurrence, P = 0.035. In patients with values below and above the median the recurrence rate was 31% and 4%, respectively. Similar results applied to EGFL7. A combined estimate identified a subgroup of patients (25 of 71) with no recurrence and a 5-year DFS and OS rate of 100%, respectively. Conclusion: MicroRNA-126 and EGFL7 are predictors for disease recurrence in patients with locally advanced colon cancer treated with neoadjuvant chemotherapy and may assist in selection of adjuvant chemotherapy.
Improving Exercise Capacity and Reducing the Risk of Falls in Osteoarthritis Patients: The Role of Perturbation and Functional Training

Research objectives included assessing the effects of Perturbation and Functional Task Training on cardiovascular endurance, strength, balance and risk of falls, ability to perform daily activities and basic functional mobility, gait speed and the ability to go out in elderly osteoarthritis patients. Both Experimental groups: Perturbation Training (PT), n=15; Functional Task Training (FT), n=15 demonstrated significant improvements in cardiovascular endurance (6 min walk distance) as compared to Control group (CG), n=15, with however no group/time interactions discovered. In strength related variables, experimental groups demonstrated specific responses in terms of time and in terms of group. In the ability to perform daily activities and basic functional mobility at the post test, FT group was significantly advantageous in scores. In stiffness scores at mid tests, PT group was significantly better than in other groups. At the post test, subjects of both intervention groups have shown significantly better scores (p< .05) than the subjects from control group. In physical function scores however no group/time interactions were discovered. In gait speed and the ability to go out at the post test, subjects of both intervention groups have shown significantly better timings (p< .05) than the subjects from CG with no significant differences between experimental groups at the post-test. In balance and risk of falls at mid tests, the scores shown by the subjects of PT group were significantly better than in FT group. At the post test, subjects of both intervention groups have shown significantly better scores (p< .05) than the subjects from the CG. There were, however no significant differences between experimental groups at the post-test.
The ‘agitation bubble ‘contrast’’ technique: A technique for using intra-peritoneal free air as contrast for the diagnosis of organ perforation

We report a case using a novel ultrasound technique to diagnose suspected bowel perforation in the presence of peritoneal fluid. Our technique removed the need for radiological confirmation and expedited surgical intervention. This highlights the potential for using this bedside ultrasonographic technique to detect free peritoneal gas in the presence of peritoneal fluid secondary to viscus perforation.
The influence of stimulus intensity on spike timing and the compound action potential in the electrically stimulated cochlea: a model study

In order to get more insight in the fundamentals of electrical stimulation of the auditory nerve by cochlear implants we developed a rotationally symmetric volume conductor model of the implanted inner ear (cochlea), using the boundary element method. The neural responses are calculated with a multiple nonlinear node model of auditory nerve fibers. In the present paper this model is used to study the relative timing of the spikes elicited in different locations in the (tonotopically organized) cochlea. This timing information is used in conjunction with the so-called unit response to synthesize compound action potentials of the auditory nerve. It is concluded that increasing the intensity of biphasic pulses on longitudinal bipolar electrodes significantly affects the time relations between spikes elicited in fibers at different positions in the cochlea. This might well have perceptual consequences, while it is poorly reflected in the compound action potential as measured at the round window.
Non-invasive markers as predictors of oesophageal varices in cirrhotic patient in a teaching hospital in Ghana

Summary Introduction Oesophageal variceal (OV) bleeding is a potentially fatal consequence of portal hypertension in patients with liver cirrhosis. Upper GI endoscopy is recommended for screening for varices in cirrhotics for early detection and treatment, however, this is invasive. The purpose of this study was to assess the predictive values of the noninvasive tests in detecting the presence of OV. Methods A cross-sectional hospital-based study involving 149 patients with liver cirrhosis was carried out at the Korle-Bu Teaching Hospital from 1st November 2015 to 25th November 2016. Relevant clinical parameters assessed included Child-Pugh class, ascites and splenomegaly. Full blood count and liver function tests, abdominal ultrasound and gastroscopy were done for all the participants. Receiver operating characteristic curve was generated to determine the cut-off values for the best sensitivity, specificity, negative and positive predictive values of the variables (serum albumin, platelet count (PC), aspartate aminotransferase (AST)/alanine aminotransferase (ALT), PC/Spleen diameter( SD)) with regard to the presence of OV. Results On gastroscopy, 135 (90.60%) had OV and 14 patients (9.40%) had no OV. One hundred and eleven of the varices (82.22%) were large varices and the rest (17.78%) small varices. The overall mean of serum albumin, PC and PC/SD were not significant predictors of the presence of OV. However, the overall mean of AST/ALT significantly predicted the presence of OV. A PC/SD cut off value of ≤833.3 had 72.62% diagnostic accuracy for diagnosing all OV. Conclusion PC/SD cut-off could be used to screen cirrhotics for OV and treatment initiated in geographical areas lacking endoscopy facilities Funding None declared
MINUMAN JAHE HANGAT UNTUK MENGURANGI EMESIS GRAVIDARUM PADA IBU HAMIL DI PUSKESMAS NALUMSARI JEPARA

Emesis gravidarum merupakan mual muntah yang terjadi selama kehamilan. Mual terjadi pada pagi hari, tetapi ada yang timbul malam hari. Data di Jawa Tengah keluhan mual muntah pada ibu hamil mencapai 40-60% dari total kehamilan. Rasa mual pada awal kehamilan dapat dikurangi dengan menggunakan terapi komplementer antara lain dengan memberikan minuman jahe hangat. Pemberian minuman jahe efektif dalam mengatasi mual muntah ibu hamil trimester I. Keunggulan jahe adalah kandungan minyak atsiri yang mempunyai efek menyegarkan dan memblokir reflek muntah, sedang gingerol dapat melancarkan darah dan saraf bekerja dengan baik. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian minuman jahe hangat terhadap emesis gravidarum pada ibu hamil trimester I di Puskesmas Nalumsari Jepara. Metode : Quasy Eksperiment dengan pendekatan Control Group Pre-Posttest Design. Populasi penelitian ini adalah ibu hamil di Puskesmas Nalumsari Jepara. Teknik pengambilan sampel menggunakan teknik Purposive Sampling sehingga besar sampel adalah 50 responden. Uji analisis data menggunakan uji Wilcoxon dan Mann Whitney. Hasil : Uji Mann Whitney mendapatkan nilai p 0.000. Kesimpulan : Terdapat pengaruh pemberian minuman jahe hangat terhadap emesis gravidarum pada ibu hamil trimester I di Puskesmas Nalumsari Jepara. Kata Kunci: jahe; emesis gravidarum
Monopodal Postural Stability Assessment by Wireless Inertial Measurement Units Through the Fast Fourier Transform.

OBJECTIVES (1) To describe the fast Fourier transform (FFT) multijoint as monopodal postural stability measurement in well-trained athletes, (2) to compare the within-subject FFT between laterality, joints, and body segments, and (3) to establish the within- and between-subject relationship between joints. METHODS Twelve national-level basketball players participated voluntarily in this investigation. The participants performed two 60-second repetitions of a monopodal stability test (1 repetition with each lower limb), separated by 3 minutes of active recovery. All tests were recorded by 4 WIMU PRO™ inertial devices located on the ankle, knee, lumbar spine, and thoracic spine. The main variable was total acceleration, where the FFT was applied. RESULTS The higher instability results were found in the ankle and in the nondominant lower limb (dominant = 1.131 [0.122] a.u. (arbitrary units); nondominant = 1.141 [0.172] a.u). In the body segment analysis, the greater percentage of differences (%diff) were shown between lumbar spine and knee in the dominant (%diff = -2.989%; d = 0.87) and nondominant (%diff = -3.243%; d = 0.90) lower limb. Finally, very large between-subjects variability was found in all joints and body segments. CONCLUSIONS The described protocol is proposed for monopodal postural stability assessment, being useful to provide information about the stability of joints and the body segment between joints. Besides, a within-subject analysis is recommended, and the FFT calculation will enable a linear analysis of each test.
The Effect of Macrophage Dose to Secretion Interleukin 6 (IL-6) on Model of Tuberculosis Granuloma In Vitro

: Granuloma is a pathological sign of host response as a system of defense against infection of Mycobacterium tuberculosis (Mtb) causing Tuberculosis (TB) disease in humans estimated to be 8.7 million new cases, 1.4 million deaths, and about 2 billion latent infections. Macrophages are responsible for activating protective immune responses in innate and adaptive immune to control or eliminate infection. The inner body protects against Mtb infection producing various secretions of cytokines interleukin 6 (IL-6) that play the role of activating multinucleated giant cells, differentiation of macrophage T cells and thus stimulating CD4 + and CD8 + T-cells to strengthen macrophage antimicrobial capacity as early response reactions (early phase). The aim of this research is to see the effect of dose of macrophage on secretion and IL-6 expression on a TB granuloma model in vitro. Human blood was made by Peripheral Blood Mononuclear Cell (PBMC) and treated with the addition of a dose of macrophages of 1x10 5 cells/well, 2x10 5 cells/well and 3x10 5 cells/well and control (without macrophages). Then the bacterium Mycobacterium tuberculosis was added and then observing the secretion The enzyme-linked immunosorbent assay (ELISA) method of IL-6 cytokine during the 1st, 2nd, 3rd, 4th, and 5th days. The results of IL-6 examination on ELISA obtained p value of 0.7520 (p> 0.05). The conclusion of the study was that there was no effect of adding macrophage dose to cytokine secretion of IL-6 levels on granuloma TB model in vitro.
Change-point analysis in frequency domain for chronological data

The purpose of this study is to provide a new methodology of how one can consistently estimate a change-point in time series data. In contrast with previous studies, the suggested methodology employs only the empirical spectral density and its first moment. This is accomplished when both the means and variances before and after the unidentified time point are unknown. Then, the well-known Gauss-Newton algorithm is applied to estimate and provide asymptotic results for the parameters involved. Simulations carried out under different distributions, sizes and unknown time points confirm the validity and accuracy of the methodology. The real-world example considered in the paper illustrates the robustness of the methodology in the presence of even extreme outliers.
Acute autoimmune myocarditis as a manifestation of Graves’ disease: A case report and review of the literature

Acute myocarditis and hyperthyroidism are common diseases that often present in young, otherwise healthy patients. Autoimmunity is central to the pathogenesis of both. Patients presenting with acute myocarditis should be screened for symptoms of hyperthyroidism, and physicians should consider screening for myocarditis in patients with hyperthyroidism and persistent cardiac symptoms.
The association of FMR1 gene (CGG)n variation with idiopathic female infertility

Introduction The FMR1 gene plays an important role in brain development and in the regulation of ovarian function. The FMR1 gene contains CGG repeat variation and the expansion of the repeats is associated with various phenotypes e.g. fragile X syndrome, premature ovarian failure, etc. Repeats ranging < 55 CGG are considered normal, however recent studies suggest that high-normal (35–54 CGG) and low-normal (< 26 CGG) alleles may also have an impact on female reproductive function. Material and methods We have performed a case-control study to assess the impact of FMR1 gene CGG repeats on female infertility. The study comprised 161 women with primary and secondary idiopathic infertility and 12 females with diminished ovarian reserve. The control group consisted of 129 healthy women with children. The FMR1 gene trinucleotide CGG repeat variation was detected using a triplet repeat primed polymerase chain reaction with capillary electrophoresis. Results The analysis of CGG repeats revealed that high-normal alleles are statistically significantly more common in the secondary infertility group than in controls (12% vs. 4.3%, p = 0.03, OR = 3.1, 95% CI: 1.1–8.3). The distribution of high-normal alleles and genotypes did not differ between patients with primary infertility and controls (p > 0.05). In addition, the analysis of low-normal allele and genotype frequencies did not present a difference between primary, secondary infertility and the control group (p > 0.05). Conclusions In our study, the FMR1 gene high-normal alleles were associated with secondary infertility. However, to address the controversies related to the role of FMR1 genes in the development of diminished ovarian reserve, further studies on the subject are required.
Under‐ice metabolism in a shallow lake in a cold and arid climate

Winter is a long period of the annual cycle of many lakes in the northern hemisphere. Low irradiance, ice, and snow cover cause poor light penetration into the water column of these lakes. Therefore, in northern lakes, respiration often exceeds primary production leading to low dissolved oxygen concentrations. This study aimed to quantify under‐ice metabolic processes during winter in an arid zone lake with little snow cover. This study was carried out in a mid‐latitude lake in Inner Mongolia, northern China. The study lake receives relatively high incoming solar radiation on the ice in mid‐winter, and radiation can penetrate down to the bottom sediment as the lake is shallow and the ice lacks snow cover. Primary production and respiration were estimated during two winters using high‐frequency sensor measurements of dissolved oxygen. To quantify under‐ice metabolic processes, sensors were deployed to different depths. During both winters, sensors collected data every 10 min over several weeks. The amount of solar radiation controlled photosynthesis under ice; temperature and photosynthesis together appeared to control respiration. The balance between gross primary production and ecosystem respiration was especially sensitive to changes in snow cover, and the balance between P and R decreased. Our data suggest that photosynthesis by plankton, submerged plants, and epiphytic algae may continue over winter in shallow lakes in mid‐latitudes when there is no snow cover on the ice, as may occur in arid climates. The continuation of photosynthesis under ice buffers against dissolved oxygen depletion and prevents consequent harmful ecosystem effects.
Cytological Evaluation of Palpable Breast Lumps: A Prospective Analysis of 84 Cases

1 Demonstrator, Department of Pathology, NSCB Medical College, Jabalpur, India 2,3 Senior Resident, Department of Radiotherapy, NSCB Medical College, Jabalpur, India *Corresponding Author Dr Lalit Mohan Patel Senior Resident, Department of Radiotherapy, NSCB Medical College, Jabalpur, India Abstract Introduction: Breast lesions are very common in India. FNAC is a reliable method for the initial evaluation and diagnosis of palpable masses of the breast. Objectives: 1. To study the cytological features of palpable breast lumps. 2. To correlate the cytological and histological features. Material and Methods: Present study was carried out on 84 patients who presented with palpable breast lumps. Cytological evaluation was done along with histological correlation. Sensitivity, specificity and diagnostic accuracy of FNAC were calculated. Results: Out of the 84 cases, 62 were benign (73.8%) while 22 were malignant (26.1%). On histological correlation, out of the 62 benign cases cytologically, 60 were benign histologically also while 2 turned out to be malignant on histology. On the other hand, out of the 22 malignant cases on cytology, 21 cases were malignant on histology as well while 1 case turned out to be benign. Conclusion: FNAC has a very high sensitivity, specificity and diagnostic accuracy along with low cost and few side effects. Thus, it is quite useful for the diagnosis of breast lumps and can be an important tool in screening of breast cancer patients.
THE CORRELATION OF CHOROIDAL THICKNESS AND OCULAR PULSE AMPLITUDE IN NON-EXUDATIVE AGE-RELATED MACULAR DEGENERATION

1 Ufuk University, Faculty of Medicine Department of Opthalmology, ANKARA 2 A¤r› State Hospital, Opthalmology Clinic, A⁄RI 3 Ankara Training and Research Hospital, Opthalmolgy Clinic, ANKARA Gülizar DEM‹ROK1 Sertaç ÖZTÜRK1 ‹lknur MÜSLEH‹DD‹NO⁄LU1 Yasemin TOPALAK1 Eflay YEN‹CE1 Burcu TABAKÇI2 Yeflim ALTAY3 Ahmet fiENGÜN1 Erol TURAÇLI1 THE CORRELATION OF CHOROIDAL THICKNESS AND OCULAR PULSE AMPLITUDE IN NON-EXUDATIVE AGE-RELATED MACULAR DEGENERATION
Experimental validation of the dynamic interaction analysis between high-speed trains and the Sesia viaduct

The EC research project ”DETAILS” aims to remove uncertainties on dynamic interaction effects of composite railway bridges. As part of the experimental part of the project, the Sesia viaduct, located on the new Italian high-speed line between Torino and Milano, has been tested under the excitation of Italian ETR500Y high-speed trains. This paper presents the finite element modeling of the Sesia viaduct, as well as the train-bridge interaction model and its implementation. To facilitate the calculation, a user friendly train-bridge interaction toolbox DATIS has been developed in Matlab that communicates with a finite element program. The toolbox is validated by comparing calculated accelerations and strains with measured results.
Assessment of somatotropic function in children with syndrome of biologically inactive growth hormone against a background of clonidine and insulin stimulation tests

Мета дослідження: оцінити ефективність фармакологічних тестів iз клонідином та інсуліном для стимуляції соматотропного гормона (СТГ) при діагностиці синдрому біологічно неактивного гормонa росту (СБНГР). Матеріали та методи. Обстежено 158 хворих на СБНГР — 47 дівчаток і 111 хлопчиків, середній вік яких становив 8,30 ± 0,24 року. У дослідження включені пацієнти з відставанням у рості понад 2 стандартнi вiдхилення. Визначали базальний та стимульований рівні СТГ із застосуванням тестів з інсуліном та клонідином. Обов’язково проводили чотириденну пробу на чутливість до гормонa росту (ГР) з визначенням рівнів інсуліноподібного фактора росту­1 до першої ін’єкції ГР і наступного дня після завершення проби. Результати. Максимальне підвищення рiвня СТГ на тлі тестів з інсуліном та клонідином в усіх пацієнтів iз СБНГР становило понад 10 нг/мл. Максимальне збільшення показників СТГ було вірогідно вищим (р < 0,01) при проведенні стимуляційного тесту з клонідином, ніж з інсуліном. Це доведено як у дітей з СБНГР — 17,79 ± 0,51 нг/мл та 13,83 ± 0,92 нг/мл відповідно, так і в контрольній групі — 16,81 ± 1,60 нг/мл і 11,18 ± 0,70 нг/мл. Зафіксовано, що індекс стандартного відхилення інсуліноподібного фактора росту­1 у хворих дітей вірогідно нижчий (р < 0,001), ніж у контрольнiй групi. Більш вираженими зміни були в пацієнтів препубертатного віку. Висновки. Фармакологічний тест iз клонідином є більш інформативним, ніж з інсуліном, і викликає вірогiдно вищий стимуляційний максимальний викид ГР. Рекомендовано розпочинати дослідження функції СТГ з проведення проби з клонідином, що є більш безпечною завдяки відсутності ризику тяжких гіпоглікемічних станів.