Miracle-dz/UniFAR-FTUs huggingface dataset:
Routine clinical outcome measures for patients with severe mental illness: CANSAS and HoNOS

Background Two recently developed measures intended for clinical use are HoNOS (Health of the Nation Outcome Scales), measuring social functioning, and CANSAS (Camberwell Assessment of Need Short Appraisal Schedule), for measuring need. Aims We investigated the association between CANSAS and HoNOS. Results For some domains there were substantial associations, with high HoNOS rating correlated with CANSAS rating of the presence of a need. For other areas the agreement was less than might be expected. Seven factors were identified within the 22 CANSAS domains, and the presence of needs in the Drug/alcohol and Activities of daily living factors was associated with high scores in the related HoNOS domains. Conclusions CANSAS and HoNOS assessments differ. HoNOS can track changes in social functioning over time, but may be less useful for treatment planning, and should not be used to infer the level of morbidity in a case-load. CANSAS indicates when treatment should be commenced or continued. It can also be used as a case-load measure, but may be insufficiently sensitive to be used as an outcome measure at the individual level.
EXPANDED VERY LARGE ARRAY OBSERVATIONS OF THE NEBULA AROUND G79.29+0.46

We have observed the radio nebula surrounding the Galactic luminous blue variable candidate G79.29+0.46 with the Expanded Very Large Array (EVLA) at 6 cm. These new radio observations allow a morphological comparison between the radio emission, which traces the ionized gas component, and the mid-IR emission, a tracer of the dust component. The InfraRed Array Camera (8 μm) and the Multiband Imaging Photometer for Spitzer (24 μm and 70 μm) images have been reprocessed and compared with the EVLA map. We confirm the presence of a second shell at 24 μm and also provide evidence for its detection at 70 μm. The differences between the spatial morphology of the radio and mid-IR maps indicate the existence of two dust populations, the cooler one emitting mostly at longer wavelengths. Analysis of the two dusty, nested shells have provided us with an estimate of the characteristic timescales for shell ejection, providing important constraints for stellar evolutionary models. Finer details of the ionized gas distribution can be appreciated thanks to the improved quality of the new 6 cm image, most notably the highly structured texture of the nebula. Evidence of interaction between the nebula and the surrounding interstellar medium can be seen in the radio map, including brighter features that delineate regions where the shell structure is locally modified. In particular, the brighter filaments in the southwest region appear to frame the shocked southwestern clump reported from CO observations.
Drivers of new product recommending and referral behaviour on social network sites

Managers of new brands seek to leverage positive WOM and establish a critical mass of consumers who interact with their brands on social network sites (SNSs). Effective selection of ‘seeds’, or influencers, on SNSs, who will recommend the product and leverage the power of their social networks to influence other consumers is key to organic growth. This research examines the role of an influencer’s activity on a social network website (network size, membership duration, share-of-posts), brand message source (marketergenerated versus member-generated), and recipient type (SNS member versus nonmember) on an influencer’s decision to recommend a new brand and the recipient’s decision to make a referral visit. Empirical analyses of clickstream data from SNSs at a commercial website show that marketer- and consumer-generated brand ads differ in their impact on recommending propensity for high share-of-posts and long-term influencers, and for member and non-member recipients, which has implications for referral management.
The impact of business incubation in shaping the entrepreneurial mindset among incubatees

II DECLARATION . III ACKNOWLEDGEMENTS.IV TABLE OF CONTENTS . V LIST OF TABLES . IX LIST OF FIGURES . XII LIST OF EQUATIONS . XIII CHAPTER 1: INTRODUCTION . 1 1.
TRANSVAGINAL PRESSURE PACK FOR LIFE‐THREATENING PELVIC HEMORRHAGE SECONDARY TO PLACENTA ACCRETA

A patient with placenta previa presented with severe vaginal bleeding. Emergency classical cesarean was followed by hysterectomy for placenta accreta. The patient's hemodynamic status continued to deteriorate and she subsequently developed a consumptive coagulopathy secondary to massive hemorrhage. A mushroom-shaped pack, created from a sterile plastic bag filled with Kerlix gauze, was placed in the pelvis and brought out through the vagina. Traction on the pack produced pressure against the pelvic floor, controlling the bleeding. This pack was prepared quickly and removed without complication in the immediate postoperative period.
The multidrug transporter MATE 1 sequesters OCs within an intracellular compartment that has no influence on OC secretion in renal proximal tubules

Martínez-Guerrero LJ, Evans KK, Dantzler WH, Wright SH. The multidrug transporter MATE1 sequesters OCs within an intracellular compartment that has no influence on OC secretion in renal proximal tubules. Am J Physiol Renal Physiol 310: F57–F67, 2016. First published November 4, 2015; doi:10.1152/ajprenal.00318. 2015. —Secretion of organic cations (OCs) across renal proximal tubules (RPTs) involves basolateral OC transporter (OCT)2-mediated uptake from the blood followed by apical multidrug and toxin extruder (MATE)1/2mediated efflux into the tubule filtrate. Whereas OCT2 supports electrogenic OC uniport, MATE is an OC/H exchanger. As assessed by epifluorescence microscopy, cultured Chinese hamster ovary (CHO) cells that stably expressed human MATE1 accumulated the fluorescent OC N ,N ,N-trimethyl-2-[methyl(7nitrobenzo[c][l,2,5]oxadiazol-4-yl)amino]ethanaminium (NBDMTMA) in the cytoplasm and in a smaller, punctate compartment; accumulation in human OCT2-expressing cells was largely restricted to the cytoplasm. A second intracellular compartment was also evident in the multicompartmental kinetics of efflux of the prototypic OC [H]1-methyl-4-phenylpyridinium (MPP) from MATE1-expressing CHO cells. Punctate accumulation of NBD-MTMA was markedly reduced by coexposure of MATE1-expressing cells with 5 M bafilomycin (BAF), an inhibitor of V-type H -ATPase, and accumulation of [H]MPP and [H]NBD-MTMA was reduced by 30% by coexposure with 5 M BAF. BAF had no effect on the initial rate of MATE1-mediated uptake of NBD-MTMA, suggesting that the influence of BAF was a secondary effect involving inhibition of V-type H -ATPase. The accumulation of [H]MPP by isolated single nonperfused rabbit RPTs was also reduced 30% by coexposure to 5 M BAF, suggesting that the native expression in RPTs of MATE protein within endosomes can increase steady-state OC accumulation. However, the rate of [H]MPP secretion by isolated single perfused rabbit RPTs was not affected by 5 M BAF, suggesting that vesicles loaded with OCs are not likely to recycle into the apical plasma membrane at a rate sufficient to provide a parallel pathway for OC secretion.
Overview of soil phosphorus data from a large international soil database

An overiew of extractable soil phosphorus (P-Bray, P-Olsen, P-Mehlich and P-water) and P-retention data held in a large profile database is presented. The primary aim is to assess whether representative P-values, by broad soil group (FAO system), can be determined for each of these analytical methods to support GIS-based assessments of food security. The study was carried in the framework of the project “Resource scarcity and distribution in a changing world” (BO-10-011-007) of the (former) Ministry of LNV (Agriculture, Nature conservation and Food quality), implemented by the Business Unit Agrosystems Research (AGRO) of Plant Research International (PRI), Wageningen University and Research Centre
Spatial spillovers from FDI agglomeration: evidence from the Yangtze River Delta in China

Foreign firms have clustered together in the Yangtze River Delta, and their impact on domestic firms is an important policy issue. This paper studies the spatial effect of FDI agglomeration on the regional productivity of domestic firms, using Chinese firm-level data. To identify local FDI spillovers, we estimate the causal impact of foreign firms on domestic firms in the same county and similar industries. We then estimate a spatial-autoregressive model to examine spatial spillovers from FDI clusters to other domestic firms in distant counties. Our results show that FDI agglomeration generates positive spillovers for domestic firms, which are stronger in nearby areas than in distant areas.
Hypoglycemic and antihyperglycemic effect of different extracts of acacia arabica lamk bark in normal and alloxan induced diabetic rats

Acacia arabica commonly known as babool are used in traditional Indian medicine for treatment of diabetes mellitus. The hypoglycemic effect of aqueous extract (hot and cold water) and hydroalcoholic extract of Acacia arabica was investigated. Oral administration of cold water extract of Acacia arabica bark to diabetic and normal rats at a dose of 400 mg/kg body weight resulted in significant reduction of blood glucose, cholesterol and triglycerides. Phytochemical investigations found that phenolic compounds are presents in Acacia arabica extracts. The cold water extract of Acacia arabica was found to reduce blood glucose level to its normal level with in seven days. Histological studies of the β-cells show its action on pancreas. Keywords: Diabetes, antidiabetics, Acacia arabica and babool.
The Spill-Over of Product Evaluations to Stock Investment Decisions: An Experiment with Finnish Individual Investors

Earlier behavioral finance research has found that individual investors’ familiarity with companies’ products may spill over to affect their decisions to invest in the companies’ stocks. However, what has not been confirmed is whether also subjective product evaluations spill over to affect investment decisions. To examine this question, the authors utilize a randomized experiment, conducted with Finnish individual investors. The experiment reveals that an individual investor’s subjective evaluation of a company’s products has positive effect on his interest to invest in the company’s stock; that this effect is independent of familiarity; and that the effect may be especially reinforced for non-domestic companies.
Good Corporate Governance Structures: A Must for Family Businesses

Corporate governance refers to the structures and processes for the direction and control of businesses and the relationships among the management, board of directors, controlling shareholders, minority shareholders and other stakeholders. Since good corporate governance contributes to sustainable economic development by enhancing the performance of companies, it is imperative that companies adopts good corporate governance structures to enable them grow. Family businesses are an often overlooked form of business ownership in today’s world, yet they constitute a majority of the businesses. This means that families own a significant share of businesses and can influence important decisions in today’s business world. However, according to Neubauer and Lank, until recently, the study of corporate governance in family business has been a largely neglected area of research [1]. As family businesses are an important component of every economy and play a critical role in promoting growth of a country’s economy, as they grow, they face same challenges and pressures as any major corporation. To succeed, they must remain ahead of the competition, adopt good corporate governance practices and skillfully navigate through market changes. This paper is an empirical study from the current authors’ previous work on the topic “Corporate Governances in Ghanaian Family Businesses: A Conceptual Framework” [2]. It examines the state of corporate governance environment and the nature of the governance system employed by family businesses using Ghanaian family businesses as a case study. The paper underlines why it is important for family businesses to adopt good corporate governance structures and attempts to understand the point of view from the subjects’ perspective, due to the complex social situations that exist in the family businesses.
Point Sets and Allied Cremona Groups.

Part Ii of this account was devoted to a study of the invariants of a set Pk of n points in Sk under the group of permutations of the points. The set as a projective figure was mapped by a point P of a space lk(n-k-2) in which the permutation group appeared as a Cremona group Gnf! In this part we shall consider the effect upon the set pk of certain Cremona transformations C in Sk These transformations C are of a special charatcer when k > 2 described hereafter by the term regular. They are determined essentially by their fundamental points alone and in all important particulars are entirely analogous to the ternary Cremona transformations. These regular Cremona transformations form the regular Cremona group in Sk. If one set of fundamental points of a regular transformation C be placed at P' there is determined a new set Pnk congruent to P' under C. The totality of sets P,' congruent in some order to a given set Pk is mapped in fk(n-k-2) by an aggregate of points P' which form a conjugate set under the extended group Gn, k of P'. This group Gn, k in " contains Gw! as a subgroup and in general is infinite and discontinuous. The major part of this article is devoted to a study of this group. In ? 5 a group gn, k of linear transformations which is isomorphic with Gn, k iS introduced. The new group brings to light properties both of Gn, k and of regular transformations in Sk. An interesting result is a determination of all types of regular transformations with a single symmetrical set of fundamental points. MIost of the types are well knob n but some are novel. In ? 6 another group en, k of linear transformations, also isomorphic with Gn, k, iS defined, which is particularly effectixe for a discussion of the infinite groups Gg,2, G8, 3, and G9,5. The close relation between the associated sets P7 and Q"-k-2 which appeared
Continuous ambulatory electrocardiography in elderly people

EDITOR,—We were not surprised by the results of Hugh Montgomery and colleagues' study of doctors' ability to interpret electrocardiograms.1 We have audited the ability of senior house officers to interpret electrocardiograms in an accident and emergency department.2 We found that only 114 of 245 traces were interpreted correctly but that management was seriously affected by misinterpretation in only …
Nonlinear Buckling Interaction for Spherical Shells Subject to Pressure and Probing Forces

Elastic spherical shells loaded under uniform pressure are subject to equal and opposite compressive probing forces at their poles to trigger and explore buckling. When the shells support external pressure, buckling is usually axisymmetric; the maximum probing force and the energy barrier the probe must overcome are determined. Applications of the probing forces under two different loading conditions, constant pressure or constant volume, are qualitatively different from one another and fully characterized. The effects of probe forces on both perfect shells and shells with axisymmetric dimple imperfections are studied. When the shells are subject to internal pressure, buckling occurs as a nonaxi- symmetric bifurcation from the axisymmetric state in the shape of a mode with multiple circumferential waves concentrated in the vicinity of the probe. Exciting new experiments by others are brieﬂy described. [DOI: 10.1115/1.4036355]
A Dual Agency View of Board Compensation: The Joint Effects of Outside Director and CEO Stock Options on Firm Risk

This paper contributes to multiple agency theory by examining how the compensation schemes awarded to outside directors and the CEO jointly affect firm-level risk taking. Using data of the SP that is, if both the outside directors and the CEO are provided with stock option compensation, outside directors' incentives weaken the effect of the CEO's incentives on firms' risk taking. Copyright © 2010 John Wiley & Sons, Ltd.
Historical Aspects of Inner Ear Anatomy and Biology that Underlie the Design of Hearing and Balance Prosthetic Devices

This review presents some of the major historical events that advanced the body of knowledge of the anatomy of the inner ear and its sensory receptors as well as the biology of these receptors that underlies the sensory functions of hearing and balance. This knowledge base of the inner ear's structure/function has been an essential factor for the design and construction of prosthetic devices to aid patients with deficits in their senses of hearing and balance. Prosthetic devices are now available for severely hearing impaired and deaf patients to restore hearing and are known as cochlear implants and auditory brain stem implants. A prosthetic device for patients with balance disorders is being perfected and is in an animal model testing phase with another prosthetic device for controlling intractable dizziness in Meniere's patients currently being evaluated in clinical testing. None of this would have been possible without the pioneering studies and discoveries of the investigators mentioned in this review and with the work of many other talented investigators to numerous to be covered in this review. Anat Rec, 2012. © 2012 Wiley Periodicals, Inc.
Free Associations with EPS and Memory

In celebrating 50 years of EPS involvement in memory, I have taken a personal line rather than trying to achieve even coverage. Accordingly, the paper is in three parts. In the first, some early papers that have resonance for today's debates are described. Their framework was Bartlettian, with versions of schema theory as the guiding principles, and they were formative in my undergraduate education. This phase ended in the 1950s. From then, there was an explosion of work in memory in the U.K., the most important parts of which saw light at the EPS. This requires a proper history, which requires a proper space. In the second part, then, rather than show favourites or sample at random, my own involvement in EPS and memory is fallibly revisited, to give some flavour of the excitement, as well as some of the ideas. In the final part, some current work is described, and the Current State Buffer is introduced, in the hope of anticipating a little of the next 50 years.
DNA repair gene polymorphisms, bulky DNA adducts in white blood cells and bladder cancer in a case‐control study

Individuals differ widely in their ability to repair DNA damage, and DNA‐repair deficiency may be involved in modulating cancer risk. In a case‐control study of 124 bladder‐cancer patients and 85 hospital controls (urological and non‐urological), 3 DNA polymorphisms localized in 3 genes of different repair pathways (XRCC1‐Arg399Gln, exon 10; XRCC3‐Thr241Met, exon 7; XPD‐Lys751Gln, exon 23) have been analyzed. Results were correlated with DNA damage measured as 32P‐post‐labeling bulky DNA adducts in white blood cells from peripheral blood. Genotyping was performed by PCR‐RFLP analysis, and allele frequencies in cases/controls were as follows: XRCC1‐399Gln = 0.34/0.39, XRCC3‐241Met = 0.48/0.35 and XPD‐751Gln = 0.42/0.42. Odds ratios (ORs) were significantly greater than 1 only for the XRCC3 (exon 7) variant, and they were consistent across the 2 control groups. XPD and XRCC1 appear to have no impact on the risk of bladder cancer. Indeed, the effect of XRCC3 was more evident in non‐smokers [OR = 4.8, 95% confidence interval (CI) 1.1–21.2]. XRCC3 apparently interacted with the N‐acetyltransferase type 2 (NAT‐2) genotype. The effect of XRCC3 was limited to the NAT‐2 slow genotype (OR = 3.4, 95% CI 1.5–7.9), suggesting that XRCC3 might be involved in a common repair pathway of bulky DNA adducts. In addition, the risk of having DNA adduct levels above the median was higher in NAT‐2 slow acetylators, homozygotes for the XRCC3‐241Met variant allele (OR = 14.6, 95% CI 1.5–138). However, any discussion of interactions should be considered preliminary because of the small numbers involved. Our results suggest that bladder‐cancer risk can be genetically modulated by XRCC3, which may repair DNA cross‐link lesions produced by aromatic amines and other environmental chemicals. © 2001 Wiley‐Liss, Inc.
Morbidity of Temporary Loop Ileostomies

Background/Aims: A temporary loop ileostomy is constructed to protect a distal colonic anastomosis. Closure is usually performed not earlier than 8–12 weeks after the primary operation. During this period, stoma-related complications can occur and enhance the adverse effect on quality of life. The aim of this study was to evaluate the length of time between ileostomy construction and closure, to quantify stoma-related morbidity and to examine the potential advantages of early ileostomy closure. Methods: Sixty-nine patients with a temporary, protective loop ileostomy (constructed between January 1996 and December 2000) were retrospectively analysed. The analysis was done by reviewing the medical records and the notes of the stoma care nurse. Results: Sixty ileostomies (87%) were closed after a median period of 24 weeks (range 2–124 weeks). Stoma-related complications occurred in 29 of the 69 patients (42%), and 11 patients (18%) had complications after ileostomy closure. Conclusion: The length of time between ileostomy construction and closure was substantially longer than initially planned. Earlier ileostomy closure (preferably even during the initial admission) could reduce the frequently occurring stoma-related morbidity in these patients and thus improve quality of life.
Allergic bronchopulmonary aspergillosis coexists with hereditary bisalbuminemia.

DOI: 10.3760/cma.j.issn.0366-6999.20132904 Department of Senior Officials Health Care (Chen X), Department of Medical Laboratory (Li J and Zhao XB), China-Japan Friendship Hospital, Beijing 100029, China Correspondence to: Dr. Chen Xin, Department of Senior Officials Health Care, China-Japan Friendship Hospital, Beijing 100029, China (Tel: 86-10-84205614. Fax: 86-10-84205614. Email: chenxin7169@ sohu.com) Clinical practice
Prediction of outcome of physiotherapy in advanced Parkinson's disease

Objective: Prediction of the effect of a home physiotherapy intervention on the basis of four clinical characteristics of patients with advanced Parkinson's disease. Design: A repeated measures design comparing six weeks without treatment with six weeks of physiotherapy and a follow-up of 12 weeks. Subjects: Persons with Parkinson's disease without dementia and suffering from considerable functional disability. Intervention: Community physiotherapists treated patients in the home situation three times a week teaching cueing and conscious movement control for walking and carrying out transfers in and out of beds and chairs. Main outcome measures: Mental status, disease severity, age and mood were included as predictor variables. A new functional scale developed as part of a previous study was used as the dependent variable administered in both the hospital and the home to determine whether the outcome generalized from the learning to a different environment. Results: Only disease severity was a negative predictor of treatment outcome at home. In the hospital setting none of the factors predicted the immediate effect of treatment but cognitive ability and age were determinants of whether the treatment effects were maintained in the long term. Conclusions: Using cueing and cognitive strategies benefited younger and older patients with Parkinson's disease alike. However, the findings indicate targeting of treatment at patients with milder disease severity and providing follow-up treatment for older and cognitively less able patients.