Miracle-dz/UniFAR-FTUs huggingface dataset:
Gait knee kinematics of patients with ACL rupture : a 3D assessment before and after the reconstruction

Because of the role of the ACL in knee joint’s biomechanics, it is essential to quantify the kinematics of ACL deficient and ACL reconstructed knee. In-vitro models bare the handicap of limited muscle simulation, while static, one-dimensional testing cannot predict the behavior of these groups of patients under realistic loading conditions. Currently, the most widely accepted method for assessing joint movement patterns is gait analysis. Respectively, 3D motion analysis is necessary to provide high reliability movement analysis. The purpose of the study was in-vivo evaluation of the behavior of the anterior cruciate ligament deficient (ACLD) and anterior cruciate ligament reconstructed (ACLR) knees during walking, using 3D, real-time assessment tool. Significant alterations of joint kinematics in the ACLD knee were revealed in this study by manifesting a higher flexion gait strategy and excessive internal tibial rotation during walking that could result in a more rapid cartilage thinning throughout the knee. In the other hand, even though ACLR knees showed some improvements in sagittal plane compared to ACLD knees, in axial plane there still exists difference compared to healthy control knees. These kinematic changes could lead to abnormal loading in knee joint and initiate the process for future chondral degeneration. However, the post-operative kinematic data were collected 10 months after surgery, so a longer follow-up is needed to evaluate if these kinematic changes persist in time, and their effects in joint degeneration
Retraction Retracted : Obesity as a Consequence of Gut Bacteria and Diet Interactions International Scholarly Research Notices

The paper titled “Obesity as a Consequence of Gut Bacteria and Diet Interactions” [1], published in International Scholarly Research Notices, has been retracted, upon the authors’ request, as it is essentially identical in content with a previously published paper by the same authors titled “Bacteria and Obesity: The Proportion Makes the Difference,” published in Surgery: Current Research (2013) 3:152.
The journey from neophyte to registered nurse : a Dutch experience

Case studies of five Dutch undergraduate students form the initial focus of this longitudinal study. An ethno-methodological approach was utilised to provide insight into how student nurses made sense of their social and personal reality and dealt with situations and challenges encountered during the four-year programme leading to registration as a degreenurse. The case studies are further examined within a meta-case study -this being the auto-ethnographic context of the researcher's role as a nurse, an educator and a researcher.The study highlights the interface between sociology and education, and between power and authority, discussing the student journey in terms of Parsonian and confluent educational frameworks. The research findings also highlight student awareness in dealing with the challenges of practice and indicate that students are proactive, and use preconceived strategies to negotiate their way through their placements successfully. Specifically a student, who dropped out of the programme, is the subject of a 'deviant' case study; her experience provides an interesting backdrop to the students who completed the programme. The researcher analyses and discusses the concept of 'deviance', questioning the appropriateness of this terminology. The study provides some insights into the original research questions regarding student motivation on entering nursing; the developmentof a 'caring philosophy, the internalisation of professional values and the ability to integrate theory and practice. In addition the richness of the researcher/student interaction adds an extra dimension to the existing body of knowledge. This narrative account invites the reader to follow the researcher's thoughts and decision-making whilst it simultaneously challenges the reader to confront their personalhistory and beliefs.
Fluctuating fortunes: genomes and habitat reconstructions reveal global climate-mediated changes in bats' genetic diversity

Over the last approximately 2.6 Myr, Earth's climate has been dominated by cyclical ice ages that have profoundly affected species' population sizes, but the impact of impending anthropogenic climate change on species’ extinction potential remains a worrying problem. We investigated 11 bat species from different taxonomic, ecological and geographical backgrounds using combined information from palaeoclimatic habitat reconstructions and genomes to analyse biotic impacts of historic climate change. We discover tightly correlated fluctuations between species' historic distribution and effective population size, identify frugivores as particularly susceptible to global warming, pinpoint large insectivores as having overall low effective population size and flag the onset of the Holocene (approx. 10–12 000 years ago) as the period with the generally lowest effective population sizes across the last approximately 1 Myr. Our study shows that combining genomic and palaeoclimatological approaches reveals effects of climatic shifts on genetic diversity and may help predict impacts of future climate change.
Low-dose sodium valproate versus low-dose propranolol in prophylaxis of common migraine headache: A randomized, prospective, parallel, open-label study

CONTEXT: Migraine is the second most common headache disorder. However, prophylactic therapy remains underutilized. AIMS: The objective of the study was to compare the efficacy and safety of low-dose sodium valproate and low-dose propranolol sustained release (SR) in the prophylaxis of common migraine headache. SETTINGS AND DESIGN: The study was conducted in a tertiary care teaching institute. It was a randomized, prospective, parallel, open-label, clinical study. SUBJECTS AND METHODS: The study included 60 patients with common migraine headaches (≥2 attacks/month) treated for 12 weeks. The patients were randomly divided into two treatment groups treated by sodium valproate 500 mg/day and propranolol SR 40 mg/day, respectively. The primary outcome measures were the percentage of responders (i.e., >50% decrease in mean headache frequency) at the end of 12 weeks and decrease in mean headache frequency (per 4 weeks) at the end of 12 weeks. The patients were assessed at 0, 4, 8, and 12 weeks of the study. STATISTICAL ANALYSIS USED: Intention-to-treat analysis was used for all the statistical analysis. RESULTS: Fifty-five patients completed the study. At the end of the treatment, both sodium valproate and propranolol caused a significant (P < 0.0001) reduction in frequency, severity, and duration of migraine headache. Propranolol caused significantly greater reduction in the severity of headache (P = 0.0410) than sodium valproate. The percentage of responders was 60% in sodium valproate group and 70% in propranolol group. Drowsiness was the most common adverse effect noted in both the groups. CONCLUSION: Both sodium valproate and propranolol significantly reduced frequency, severity, and duration of migraine headache, but propranolol caused significantly greater reduction in the severity of headache compared to sodium valproate. Both the medications were well tolerated and did not result in discontinuation.
Gap-type dark localized modes in a Bose–Einstein condensate with optical lattices

Abstract. Bose–Einstein condensate (BEC) exhibits a variety of fascinating and unexpected macroscopic phenomena, and has attracted sustained attention in recent years—particularly in the field of solitons and associated nonlinear phenomena. Meanwhile, optical lattices have emerged as a versatile toolbox for understanding the properties and controlling the dynamics of BEC, among which the realization of bright gap solitons is an iconic result. However, the dark gap solitons are still experimentally unproven, and their properties in more than one dimension remain unknown. In light of this, we describe, numerically and theoretically, the formation and stability properties of gap-type dark localized modes in the context of ultracold atoms trapped in optical lattices. Two kinds of stable dark localized modes—gap solitons and soliton clusters—are predicted in both the one- and two-dimensional geometries. The vortical counterparts of both modes are also constructed in two dimensions. A unique feature is the existence of a nonlinear Bloch-wave background on which all above gap modes are situated. By employing linear-stability analysis and direct simulations, stability regions of the predicted modes are obtained. Our results offer the possibility of observing dark gap localized structures with cutting-edge techniques in ultracold atoms experiments and beyond, including in optics with photonic crystals and lattices.
Parental Coordination of Chick Provisioning in a Planktivorous Arctic Seabird Under Divergent Conditions on Foraging Grounds

An increasing number of studies report coordinated chick provisioning by avian parents. Although the pattern of parental coordination varies across species, broad occurrence of this coordination suggests that it has an adaptive value: it may increase individual fitness via higher offspring survival, faster offspring growth rate and/or higher body reserves of the parents. However, to what extent the pattern of coordinated provisioning in a species represents a flexible response to current foraging conditions remains an open question. Here, we examined coordination of chick provisioning in the Little Auk (Alle alle), a planktivorous seabird species that breeds in the Arctic. Harsh environmental conditions impose bi-parental care on this species, and high variability within and across breeding seasons promotes flexibility in parental involvement to secure breeding success. During the chick rearing period, parents exhibit a dual-foraging strategy (i.e. alternating long foraging trips, serving to maintain the adults’ body reserves, with several short trips aimed to provision the chick). We examined coordination of parental provisioning across five breeding seasons varying in terms of environmental conditions and found that the parents indeed coordinate their provisioning, avoiding performing long trips simultaneously and thus enabling a more even distribution of feeding through time. We also examined chick body condition in relation to the level of parental coordination to test the potential adaptive value of coordination, but we found no significant relationship between these two parameters. We found high variability in the level of the coordination between pairs, and this variability was similar across all study seasons, which represented a wide range of experienced environmental conditions. Nevertheless, we found that the energy density of food loads delivered to chicks was associated with the level of parental coordination: when conditions were characterised by the delivery of higher-energy food loads, the level of coordination exhibited by the studied population was higher. These findings suggest that environmental conditions somehow affect parental coordination, but the range of the environmental variation could be still below a critical threshold of extreme conditions that would trigger more pronounced modifications of parental foraging patterns and coordination.
Talking to Stupid?!? Improving Voice User Interfaces

Worldwide, voice user interfaces (voice UIs) are on the rise by being integrated in smartphones, computers, smart home devices and many more consumer goods. Although users praise the possibilities certain functions offer, many users show reservations when it comes to using speech assistants regularly in daily life. A research and conception project at the strategic design agency designaffairs in Munich demonstrates that users especially praise devices with voice UIs for the functionality they offer, such as music or smart home appliances. Reasons for disliking or not using voice systems are mostly problems with speech recognition and limited functionality. Based on the insights from user research, important factors for the development of a voice UI concept are identified in a workshop with subject ma#er experts (SMEs). $e focus is set on user interaction and dialog design. $ese factors are validated with users by conducting a conjoint analysis. Here, users prefer gesture input as activation method and the dialog behavior to consist of no humor and no answer variety. A so%ware prototype with this dialog behavior is developed in order to test it with real users in a user test. Although the prototype is rated be#er than other devices on the market, users’ comments indicate that the dialog behavior is not considered ideal for all users. Some users view their voice UI rather as a neutral assistant which should therefore be efficient, brief and concise in answering requests. By contrast, other users wish for a friendly companion which is assisting in a human-like, sympathic way. $us, developing one speech assistant appropriate for all users calls for the possibility to customize certain features, such as dialog behavior. $e project results show that a user centered design approach is helpful in developing usable products. Further concept improvement must be made especially in the field of speech recognition & processing.
Grouper TRADD Mediates Innate Antiviral Immune Responses and Apoptosis Induced by Singapore Grouper Iridovirus (SGIV) Infection

Tumor necrosis factor (TNF) receptor type 1-associated DEATH domain protein (TRADD) is a TNFR1-associated signal transducer and an essential component of the TNFR1 complex that is involved in activating both apoptotic and nuclear factor (NF)-κB pathways as an adaptor. It also is required for TNFR-1-initiated neuronal apoptosis following in vitro infection with virus as an essential component of the antiviral response. To date, few studies have investigated the function of TRADD in lower vertebrates and its antiviral response to DNA virus infection. In the present study, a TRADD gene (named as EcTRADD) from the orange-spotted grouper (Epinephelus coioides) was cloned and characterized. The full-length cDNA of EcTRADD consists of 1,370 base pairs (bp) and contains a 44 bp 5′-terminal untranslated region (UTR), a 450 bp 3′-UTR including a poly (A) tail, and an 876 bp open reading frame encoding a putative 291 amino acid protein. EcTRADD has two conserved domains of N-terminal domain (TRADD-N) and a death domain (DD). EcTRADD was detected in all examined tissues. EcTRADD was up-regulated in the spleen after infection with Singapore grouper iridovirus (SGIV). Subcellular localization analysis revealed that EcTRADD and EcTRADD-DD exhibited a clear pattern of discrete and interconnecting cytoplasmic filaments resembling the death-effector filaments, while EcTRADD-N was observed in the cytoplasm. After infection with SGIV, EcTRADD, and EcTRADD-DD were transferred to the nucleus. Overexpression of EcTRADD and its domains inhibited replication of SGIV in vitro. Both EcTRADD and EcTRADD-DD induced the caspase-dependent apoptosis in control and infected cells, while EcTRADD-N inhibited the apoptosis. Additionally, EcTRADD and EcTRADD-DD significantly promoted activation of NF-κB and reporter gene p53, whereas EcTRADD-N had no significant effect on p53. The results may provide new insights into the role of fish TRADD in fish virus infection.
Évaluation comparative de stratégies visant à augmenter les interventions de courte durée en cessation tabagique auprès du personnel infirmier de milieux hospitaliers

Introduction : Research results demonstrate a decrease in cigarette smoking when preventive professional interventions are routinely carried out. The Quebec recent literature reports that, nurses from different working areas assess their patient smoking habits 62 % of the time and recommend cessation in only 38 % of the situations. When this assessment is realized by hospital nurses, this percentage drops around 30 %. Knowing that nursing staff is present at the bedside 24 hours a day, a non-negligible influence of tobacco counselling by nurses is of potential interest for hospitalized patients. The objective of the present study is to compare, on medical and surgical units, the effectiveness of three strategies (interactive educational session, recall, and both together) to a control group, on the number of nursing interventions pertaining to cessation of cigarette smoking. Choice of those three strategies is based on reported effectiveness and transferability potential. Research design is experimental with group randomisation. Factorial model opens possibility to assess impact of each of the three strategies versus the control group. Pre and post strategy multi-measurements (at 1 and 3 months) are sought from nursing staff, patients, patient charts, management, nurses in charge of the centers for tobacco cessation. Results : Nursing staff completed questionnaires at time 1 (N = 156), at time 2 (N= 78), and at time 3 (N=69). Similarly, 156 patients were interviewed at time 1, 89 at time 2, and 98 at time 3. Results show that nursing staff assesses cigarette smoking habits for only 35,7 % of the patients, and their intent to stop smoking only 17,6 % of the time. Very few tobacco counselling interventions are carried out on medical and surgical units by nursing staff. Some barriers are identified, and nursing staff perceives a non-self-efficacy with regard to those interventions. Results do not allow confirmation of hypotheses. However, complementary statistical analyses show that the educational strategy increases the number of nursing interventions during a short period, and decreases perception of barriers to tobacco counselling. Impact of recall could not be assessed as it was not introduced as planned. Conclusion : Considering modest results from the strategies, the interactive
Assessing the Intent and Effectiveness of Carbon Footprint Calculators

In the context of addressing global warming issues, one of the possible approaches is to provide individuals with tools that support change toward greener practices, as for example around commuting. This paper illustrates a study that we conducted on the effectiveness of self-tracking of commuting data where participants received daily feedback on the financial costs and CO2 emissions associated to their mobility practices. In the results, we describe situations where users do not accept the data and the models utilized to represent them, highlighting a limitation that diary instruments (and underlying models) of this type would have in supporting people to question and possibly change their mobility choices. On the basis of the study findings, we also describe a new model aimed at overcoming some of the limitations that the study showed, in particular by better connecting the individual environmental impact with the collective one.
Adaptive Dark Mode: Investigating Text and Transparency of Windshield Display Content for Automated Driving

Windshield displays are a promising technology for auto-motive application. In combination with the emergence of highly automated vehicles, chances are that work-related activities will become more popular on the daily commute to and from work. While windshield displays can show content relevant for non-driving related activities, little information is available on how potential users would utilize these displays in terms of text and background color as well as trans-parency usage. In this paper, we present the results of two user studies (pilot study: N = 10, main study: N = 20) addressing this issue. Findings from quantitative measurements and qualitative pre-/post study surveys and interviews suggest a strong preference for the chat window being located
Satisfaction of Basic Psychological Needs Leads to Better Academic Performance via Increased Psychological Capital: A Three-Wave Longitudinal Study Among High School Students

This brief report proposes a model in which academic psychological capital (PsyCap) mediates between the satisfaction of student’s basic psychological needs and their academic performance, as assessed by students’ GPA. Participants were 407 adolescents, aged 12–18, recruited from three Chilean schools. Through structural equation modeling, direct and indirect effects were calculated. Results show that academic PsyCap (assessed at time 2) fully mediates the relationship between the satisfaction of basic psychological needs (assessed at time 1) and academic performance (assessed at time 3). This means that students whose basic psychological needs are satisfied at school experience more hope, efficacy, resilience, and optimism (PsyCap), which, in turn, leads to better academic performance. Both theoretical and practical implications of the results are addressed, as well as strengths and weaknesses and directions for future research.
Testing Odd Direct Sums Using High Dimensional Expanders

In this work, using methods from high dimensional expansion, we show that the property of k-direct-sum is testable for odd values of k . Previous work of [9] could inherently deal only with the case that k is even, using a reduction to linearity testing. Interestingly, our work is the first to combine the topological notion of high dimensional expansion (called co-systolic expansion) with the combinatorial/spectral notion of high dimensional expansion (called colorful expansion) to obtain the result. The classical k-direct-sum problem applies to the complete complex; Namely it considers a function defined over all k-subsets of some n sized universe. Our result here applies to any collection of k-subsets of an n-universe, assuming this collection of subsets forms a high dimensional expander.
What Is My Next Step? School Students' Perceptions of Feedback

Feedback literature is dominated by claims of large effect sizes, yet there are remarkable levels of variability relating to the effects of feedback. The same feedback can be effective for one student but not another, and in one situation but not another. There is a need to better understand how students are receiving feedback and currently there is relatively little research on school students' perceptions of feedback. In contrast, current social constructivist and self-regulatory models of feedback see the learner as an active agent in receiving, interpreting, and applying feedback information. This paper aims to investigate school student perceptions of feedback through designing a student feedback perception questionnaire (SFPQ) based upon a conceptual model of feedback. The questionnaire was used to collect data about the helpfulness to learning of different feedback types and levels. Results demonstrate that the questionnaire partially affirms the conceptual model of feedback. Items pertaining to feed forward (improvement based feedback) were reported by students as most helpful to learning. Implications for teaching and learning are discussed, in regard to how students receive feedback.