Miracle-dz/UniFAR-FTUs huggingface dataset:
Toxicity of Hypofractionated Radiotherapy Following Breast Conservative Surgery in Breast Cancer

Background:Adjuvant radiotherapy has increased disease-free and overall survival rates in breast cancer. Conventionally fractionated radiotherapy delivers 50 Gy over 5 weeks which is the standard approach. A shorter duration of hypofractionated radiotherapy (HFRT) will be more convenient for patients and treatment providers if found safe and equally effective. Material and Methods: Fifty-four breast cancer patients who underwent breast conservative surgery (BCS) were enrolled in this study. The patients received 4005 cGy/15 fractions. A boost to the tumor bed was administered in all patients. In this study, radiotherapy induced toxicity was evaluated. Results: In this study, the median age of our patients was 48 years with age ranged from 28 to 69 years. Acute skin toxicity was assessed, and it was noted that grade 2 skin toxicity was shown in only 6 patients (11.1%) at the end of radiotherapy and disappeared after 6 weeks of treatment. Late skin toxicity (telangectasia, hyperpigmentation, and subcutaneous fibrosis) was assessed and showed that most patients had grade 0 toxicity with no grade 3 toxicity at all. Regarding pulmonary toxicity, 5 patients (9.3%) developed acute pneumonitis and as regards chronic lung toxicity, it was evident in only 3 patients, 2 patients (3.7%) were grade 1 and 1 patient (1.9%) was grade 2. Cardiac toxicity was evident in 2 patients (7.1%) of the left breast cancer patients. Regarding lymphoedema, most patients that showed lymphoedema were grade 1. Conclusion: The results confirm the safety and feasibility of adjuvant hypofractionated whole breast radiotherapy in breast cancer patients in terms of acute and late toxicity.
Determination of complex formation constants of neptunium(V) with propionate and lactate in 0.5–2.6 m NaCl solutions at 22–60°C using a solvent extraction technique

Abstract Natural clay rocks like Opalinus (OPA) and Callovo-Oxfordian (COx) clay rock are considered as potential host rocks for deep geological disposal of nuclear waste. However, small organic molecules such as propionate and lactate exist in clay rock pore water and might enhance Np mobility through a complexation process. Therefore, reliable complex formation data are required in the frame of the Safety Case for a nuclear waste repository. A solvent extraction technique was applied for the determination of NpO2+ ${\rm{NpO}}_2^ + $ complexation with propionate and lactate. Extraction was conducted from isoamyl alcohol solution containing 10−3 M TTA and 5 · 10−4 M 1,10-phenanthroline. Experiments were performed in 0.5–2.6 m NaCl solutions at temperatures ranging from 22 to 60 °C. Formation of 1:1 Np(V) complexes for propionate and lactate was found under the studied conditions. The SIT approach was applied to calculate equilibrium constants β°(T) at zero ionic strength from the experimental data. Log β°(T) is found linearly correlated to 1/T for propionate and lactate, evidencing that heat capacity change is near 0. Molal reaction enthalpy and entropy ( ΔrHm∘ ${\Delta _{\rm{r}}}H_{\rm{m}}^ \circ $ and ΔrSm∘ ${\Delta _{\rm{r}}}S_{\rm{m}}^ \circ $ ) could therefore be derived from the integrated van’t Hoff equation. Data for log β° (298.15 K) are in agreement with literature values for propionate and lactate. Np(V) speciation was calculated for concentrations of acetate, propionate and lactate measured in clay pore waters of COx. In addition, the two site protolysis non-electrostatic surface complexation and cation exchange (2SPNE SC/CE) model was applied to quantitatively describe the influence of Np(V) complexation on its uptake on Na-illite, a relevant clay mineral of OPA and COx.
Comparison and assessment of large-scale surface temperature in climate model simulations

Abstract. We present a data-driven approach to assess and compare the behavior of large-scale spatial averages of surface temperature in climate model simulations and in observational products. We rely on univariate and multivariate dynamic linear model (DLM) techniques to estimate both long-term and seasonal changes in temperature. The residuals from the DLM analyses capture the internal variability of the climate system and exhibit complex temporal autocorrelation structure. To characterize this internal variability, we explore the structure of these residuals using univariate and multivariate autoregressive (AR) models. As a proof of concept that can easily be extended to other climate models, we apply our approach to one particular climate model (MIROC5). Our results illustrate model versus data differences in both long-term and seasonal changes in temperature. Despite differences in the underlying factors contributing to variability, the different types of simulation yield very similar spectral estimates of internal temperature variability. In general, we find that there is no evidence that the MIROC5 model systematically underestimates the amplitude of observed surface temperature variability on multi-decadal timescales – a finding that has considerable relevance regarding efforts to identify anthropogenic “fingerprints” in observational surface temperature data. Our methodology and results present a novel approach to obtaining data-driven estimates of climate variability for purposes of model evaluation.
Estimating MIC distributions and cutoffs through mixture models: an application to establish M. Tuberculosis resistance

Antimicrobial resistance is becoming a major threat to public health throughout the world. Researchers from around the world are attempting to contrast it by developing both new antibiotics and patient-specific treatments. It is, therefore, necessary to study these treatments, via phenotypic tests, and it is essential to have robust methods available to analyze the resistance patterns to medication, which could be applied to both new treatments and to new phenotypic tests. A general method is here proposed to study minimal inhibitory concentration (MIC) distributions and fixed breakpoints in order to separate sensible from resistant strains. The method has been applied to a new 96-well microtiter plate.
Experimental Investigation of selected supramolecular systems by NMR spectroscopy

Title: Experimental Investigation of Selected Supramolecular Systems by NMR Spectroscopy Author: Mária Šoltésová Department: Department of Low Temperature Physics Supervisor: RNDr. Jan Lang, Ph.D. Supervisor’s e-mail address: Jan.Lang@mff.cuni. cz Abstract: The thesis describes investigation of two selected supramolecular systems by means of NMR spectroscopy and hydrodynamic calculations. The first system studied was inclusion complex of cryptophane-C with chloroform. Initially, the kinetics of complexation was determined. The measurements of longitudinal relaxation and heteronuclear Overhauser enhancement on carbon-13 nuclei revealed very large motional coupling between the host and the molecular guest bound inside the cavity. Hydrogen bonded clusters of ethanol in a non-polar solvent were the second system addressed. The diffusion coefficients of ethanol were measured in a broad temperature range (180 – 330 K) by means of NMR spectroscopy. The average cluster sizes dependent upon experimental conditions were determined. At low temperature (around 180 K), the cluster sizes vary from hexamer (0.16 M sample) to octamer or larger structures (1.4 M sample). On the other hand, the average cluster size at ambient temperature corresponds to trimer (1.4 M), pure monomer occurs in the less concentrated sample above 308 K. Experimental results for monomer are in excellent agreement with the calculated values. The thesis describes investigation of two selected supramolecular systems by means of NMR spectroscopy and hydrodynamic calculations. The first system studied was inclusion complex of cryptophane-C with chloroform. Initially, the kinetics of complexation was determined. The measurements of longitudinal relaxation and heteronuclear Overhauser enhancement on carbon-13 nuclei revealed very large motional coupling between the host and the molecular guest bound inside the cavity. Hydrogen bonded clusters of ethanol in a non-polar solvent were the second system addressed. The diffusion coefficients of ethanol were measured in a broad temperature range (180 – 330 K) by means of NMR spectroscopy. The average cluster sizes dependent upon experimental conditions were determined. At low temperature (around 180 K), the cluster sizes vary from hexamer (0.16 M sample) to octamer or larger structures (1.4 M sample). On the other hand, the average cluster size at ambient temperature corresponds to trimer (1.4 M), pure monomer occurs in the less concentrated sample above 308 K. Experimental results for monomer are in excellent agreement with the calculated values.
Effects of nano-copper on maize yield and inflammatory response in mice

Objective(s): Copper (Cu) is an essential dietary supplement in animal feeds, which plays an important role in maintaining the balance of all living organisms. Copper nanoparticles (nCu) participate in catalysing activities of multiple antioxidant/defensive enzymes and exerts pro-inflammatory and pro-apoptotic effects on systemic organs and tissues. The present study explored whether nCu affects maize growth and yield and grain mineral nutrients as well as physiological functions in mice. Materials and Methods: Maize seeds were treated with nCu (20 mg/kg and 1000 mg/kg dry weight (DW)) and their grain productions were used for mouse feed. For testing of autoimmune response, mice were treated with nCu at concentration of 2 mg/l and 1000 mg/l and ultimately serum biochemical indicators, numbers and activation of immune cells infiltrated in mouse spleens were examined. Results: Treatment of maize seeds with nCu at dose of 20 mg/kg DW, but not 1000 mg/kg DW enhanced germination rate, plant growth and grain yield as well as grain mineral nutrients as compared to control group. Importantly, administration of mice with 1000 mg/l nCu resulted in their morphological change due to excessive accumulation of nCu in liver and blood, leading to inflammatory responses involved in upregulated expression of serum biochemical indicators of liver and kidney as well as increased infiltration and activation of splenic immune cells. Conclusion: nCu concentration at 20 mg/kg DW facilitated the morphological and functional development of maize plants, whose production was safe to feed mice.
Développement des capacités métalinguistiques chez des élèves apprenant une langue étrangère en utilisant la poésie

La these actuelle propose un modele interactif de capacite metalinguistique, de poesie et d'apprentissage des langues etrangeres. Elle vise a examiner l'influence du cours d'anglais langue etrangere base sur la poesie sur la capacite metaphonologique des eleves, et a explorer des relations entre leur capacite metaphonologique et les facteurs d'apprentissage tels que la pedagogie des enseignants, les strategies d'apprentissage des langues des apprenants, l'exposition linguistique a l’anglais en dehors de la classe et les commentaires des eleves sur le cours d’anglais auquel on a integre de la poesie. Deux etudes de cas visent a enqueter sur le developpement de la capacite metaphonologique des eleves dans le cours d’anglais avec poesie, ainsi que les relations mentionnees ci-dessus. Une combinaison de methodes quantitatives et de methodes qualitatives est utilisee dans cette these. Les resultats de la quasi-experience indiquent que la classe d'anglais prenant appui sur la poesie facilite le developpement de la capacite metaphonologique des eleves dans une certaine mesure. La theorie de Bialystok (2001, 2012), la « noticing hypothesis » de Schmidt (Schmidt, 2010) et la poetique cognitive de Tsur (2008) sont utilisees pour analyser et expliquer les resultats des tests de capacite metaphonologique.
Resilient control of switched systems in conditions of input delay and cyber attacks

The subject of this article is to propose novel resilient control strategies for switched systems in conditions of input delay and cyber-attacks. At first it is assumed that the attacker can access the sensor of the system and consequently injects unknown false data to the sensor. Next, it is assumed that attacker can access the control block channel and consequently injects unknown nonlinear false data to the controller and also simultaneously can access the actuator, resulting in the loss of effectiveness of the actuator. In such conditions, novel resilient control strategies are proposed to keep the performance of the attacked system up to a reasonable security bound. To achieve resilience in such conditions, Lyapunov–Krasovskii functional method is applied to show the uniformly ultimately bounded behavior of the system. Finally, for an evaluating approach, two illustrative examples will be solved.
Analysis of MSME Actors’ Behavior in Preparing Financial Statements With Modified Theory of Planned Behavior

This research aimed to examine factors that can increase the MSME actors’ interest in preparing financial statements dan relate this interest to the MSME actors’ actual behavior of preparing financial statements. This research modified the Theory of Planned Behavior (TPB) by adding ‘self-efficacy’ construct. This research employed a survey method by using questionnaires to collect the data from the research samples of MSME actors assisted by PT. Semen Indonesia (Persero) Tbk. The samples selected were those who had prepared financial statements, amounted to 100 respondents. Moreover, the researcher used a Partial Least Square (PLS) in the data analysis. The results showed that ‘interest’ construct positively affected the MSME actors’ behavior of preparing financial statements. Attitudes, subjective norms, behavioral control, and self- efficacy also had a positive effect on the MSME actors’ interest in preparing financial statements. The implications of the results of this research can be used as evaluation materials by the Partnership and Environmental Development Programs of PT. Semen Indonesia (Persero) Tbk. to create more MSME actors with the capability of preparing financial statements. This capability can facilitate the process of monitoring and evaluating the performance of MSMEs by providing the required factors through training and development programs.
High Security Data Hiding in Videos Using Multi-Frame, Image Cropping and LSB Algorithm

An art of invisible communication by embedding secret information in other sources like text, image, audio, and video is called steganography. A high security data hiding technique is proposed in this paper. Selected frames from the video are cropped into four equal parts, block of secret data is hiding in each three channels of crop of a frame using LSB technique in a predefined sequence, and then image crops are joined to get stego image/ frame. This stego frame is replaced in video in its original position. Comparative study is performed between proposed approach and existing approach using different metrics such as visualization test, MSE, PSNR and CPU time. Experimental results shows that the proposed approach is more secure compared to the existing approach.
Interannual variability of Indonesian throughflow in the Flores Sea

The main branch of Indonesian Throughflow (ITF) from Makassar Strait passes through Flores Sea. The variance of ITF transport volume was influenced by climate phenomenon such as El Nino Southern Oscillation (ENSO). This research was conducted to describe the relationship between the ENSO and the ITF transport variability. This relationship was explored using data from INDESO model 2008-2015. The variability of transport volume was analyzied using continous wavelet transform and band-pass analysis. Water circulation was analyzed by summing up the average of water current and sea temperatures. The Flores ITF was a portion of Makassar ITF and Eastern ITF that enter via Lifamatola Passage. The flow in the upper layer was intensified during the west monsoon while in the thermocline layer was intensified during the east monsoon. Flores ITF moved along the northern part of Flores Island and was dominated by zonal velocity component.
Experimental investigation of flow control devices effect on inclusion separation in a four strand tundish

ABSTRACT In continuous casting, molten steel often contains non-metallic inclusions that have a very high melting temperature and thus remain suspended in the molten flow. Given the lower density of these substances compared to the melt, they can be filtered in the form of top slag by proper use of buoyancy forces. Thus, providing a desirable flow pattern, reduced flow turbulence, and adequate residence time for inclusions in the tundish will improve the inclusion separation performance and therefore the product quality. In this study, a reduced-scale water model of a tundish was used to evaluate the effect of melt level in the tundish on the flow pattern and inclusion separation performance. Then, the flow control devices are added to this simple tundish model to examine the effect of them on the flow behaviour and inclusion separation. Experimental investigation showed that raising the water level in the model tundish has desirable effects on inclusion separation and the use of the dam at the inlet with tall dam improves the flow pattern and inclusion separation almost 20% in the form of top slag.
Biodegradation of Carbamothioates in Butylate-History Soils

Laboratory experiments were conducted to evaluate the biodegradation of 14C-labeled butylate, cycloate, EPTC, pebulate, and vernolate in three butylate-history soils that had received three to eight applications of butylate under field conditions. After 20 days, biodegradation of butylate and EPTC was accelerated and had no lag phase in all three butylate-history soils. Butylate-adapted microorganisms were cross-adapted for EPTC and degraded EPTC as readily as butylate. Biodegradation of butylate and EPTC in Dothan soil without a butylate history exhibited a lag phase of 6 days after which 14CO2 was evolved at an exponential rate. This indicated that enhanced biodegradation was induced after one application of butylate or EPTC. Butylate-adapted microorganisms were cross-adapted for vernolate and pebulate in Dothan and pebulate in Wagram soils with a butylate history. Biodegradation of vernolate and pebulate was not enhanced in Varina butylate-history soil. After 20 days, there was no cross-adaptation for cycloate in any soil. These findings indicated that biodegradation of carbamothioates was influenced by soil type and previous carbamothioate use and that caution should be exercised in use of EPTC on fields of previous butylate use.
Psychological Research on Organisational Democracy: A Meta‐Analysis of Individual, Organisational, and Societal Outcomes

© 2019 The Authors. Applied Psychology published by John Wiley & Sons Ltd on behalf of International Association of Applied Psychology. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. Psychological Research on Organisational Democracy: A Meta-Analysis of Individual, Organisational, and Societal Outcomes
The Impact of Transport Infrastructure on International Inbound Tourism – A Gravity Model for Poland

Background. Development of the tourism sector depends on the infrastructure and an efficient transportation system. A better transport infrastructure results in lower transportation costs and thus lower variable costs of trading, and shortens the distance between origin and destination countries, which can stimulate international tourism flows. Significant improvements in the accessibility of general transport infrastructure (road and air) in Poland within other factors have potentially their effect on foreign inbound tourism. Research aims. The aim of this article is to determine the importance of transport infrastructure among other classical factors of a gravity model influencing foreign inbound tourism to Poland (such as geographic and economic distance from tourism origin countries, or perceived risk factors in the origin countries, like terrorism and economic crises). Methodology. The study is based on panel data of bilateral tourism flows in the period 2008–2016 from 33 countries trading with Poland. We applied a gravity model for international tourism flows considering four different sub-panels (disaggregated by countries and time) in order to control the role of infrastructure in various data sets. Key findings. The results show that the level of transport infrastructure development – measured both directly and indirectly – has a significant impact on foreign inbound tourism to Poland.
Mesure in situ de la perte par insertion d'un prototype de protection antibruit de faible hauteur adaptée au tramway

La performance acoustique d’un prototype d’ecran antibruit de faible hauteur adaptee a la reduction du bruit de tramway pour les recepteurs proches (pietons et cyclistes) a ete mesuree in situ. Le prototype est un assemblage de planches de bois agglomere en forme de L inverse couvert de laine de verre sur le cote expose aux sources de bruit. Il a ete installe temporairement dans un quartier residentiel a Saint-Martin-d’Heres, pres de Grenoble, au travers duquel passe une ligne de tramway. Une serie de mesures de niveaux au passage ont ete effectuees a une position proche correspondant a une hauteur typique d’oreilles humaines (1.50m), ainsi que la vitesse du tramway grâce a un microphone auxiliaire place tres pres de la voie, avec et sans le prototype. Malgre l’application d’une correction de vitesse sur le niveau moyen pendant le passage, on trouve une assez forte variabilite entre les differents tramways. La presence de l’ecran cause cependant une reduction de plus de 10 dB(A) pendant le passage des trams les plus proches de la protection. La perte par insertion est aussi etudiee dans le domaine frequentiel, ce qui permet notamment d’analyser les bandes de frequences avec un bon rapport signal sur bruit.
TINGKAT DENSITAS LARVA BOTIA (Chromobotia macracanthus) DALAM SATUAN VOLUME AIR PADA AKUARIUM SISTEM RESIRKULASI

Rendahnya sintasan larva dipengaruhi oleh beberapa faktor di antaranya kualitas air, ketersediaan pakan dan padat tebar. Padat tebar merupakan salah satu variabel yang sangat penting dalam bidang budidaya karena berpengaruh secara langsung terhadap sintasan, pertumbuhan, tingkah laku, kesehatan, kualitas air, pemberian pakan, dan produksi. Tujuan dari penelitian ini adalah untuk mengetahui padat tebar optimal pemeliharaan dalam akuarium sistem resirkulasi yang dapat menghasilkan sintasan larva botia tertinggi. Larva botia dipelihara selama 31 hari dalam akuarium berukuran 30 cm x 20 cm x 20 cm yang dilengkapi dengan sistem resirkulasi yang diisi air sebanyak 5 liter. Perlakuan dalam penelitian ini adalah padat tebar yang berbeda yaitu: A. 15 ekor/L, B. 20 ekor/L, C. 25 ekor/L, D. 30 ekor/L, dan E. 35 ekor/L. Masing-masing perlakuan diulang sebanyak tiga kali dan rancangan percobaan yang digunakan adalah Rancangan Acak Lengkap. Pakan yang diberikan selama penelitian adalah nauplii Artemia . Hasil penelitian menunjukkan bahwa padat tebar tidak memberikan pengaruh yang nyata terhadap sintasan, namun memberikan pengaruh terhadap pertumbuhan panjang larva botia. Sintasan dari masing-masing perlakuan adalah A. 96,45%; B. 96,67%; C. 97,07%; D. 96,22%; dan E. 95,81%. Pertumbuhan panjang larva botia tertinggi dihasilkan pada padat tebar 15 ekor/L yaitu 9,67 mm.