Miracle-dz/UniFAR-FTUs huggingface dataset:
Sibling Relationships in Emerging Adulthood and in Adolescence

In this study, 116 emerging adults and adolescents completed questionnaires and were interviewed about their relationship with a sibling. Respondents’ siblings and their mothers also rated the quality of the sibling relationship. Emerging adults were found to spend less time and to be less involved in joint activities with their siblings than adolescents, but they reported being more involved in emotional exchanges with and feeling more warmth toward their siblings. Conflict and rivalry were also reported by emerging adults to be less intense than by adolescents. Narrative analyses showed that emerging adults had a more mature perception of their relationship with their siblings. Unlike in adolescence, the quality of emerging adults’ relationships with their siblings was less related to their relationship with their parents. The results are discussed in the framework of changes in close relationships from adolescence to emerging adulthood.
Neuropsychological long-term sequelae of perinatal asphyxia

Objective : To investigate the long-term neuropsychological consequences of perinatal asphyxia (PA). Methods : A group of adolescents were assessed with antecedents of mild ( n = 8) and moderate ( n = 20) PA, and a matched group of 28 healthy adolescents as a control group. Neuropsychological assessment included tests of memory, perceptual-motor skills, and frontal lobe functions, because these are areas of cognitive functioning susceptible to hypoxic conditions. Results : Subjects with moderate PA showed significant differences from the control group on tests related to delayed recall for both verbal and visual information, perceptual-motor speed, and tests assessing attention and executive functions. Conversely, subjects in the mild PA group exhibited scores which were similar to those of the control group in all the assessed variables. Conclusion : The present findings demonstrate that subtle but persistent neuropsychological deficits were observed in adolescents with antecedents of moderate PA, but not in those classified with mild asphyxia.
Enumeration of vital and thermally stressed Staphylococcus aureus in foods using Baird-Parker pig plasma agar (BPP).

Baird-Parker (BP), modified BP medium (egg yolk replaced with pig plasma, BPP) and modified Vogel and Johnson agar (phosphatidyl choline, deoxyribonucleic acid, with catalase added, PCVJ) were equally efficient for enumerating both non-stressed and thermally-stressed populations of Staphylococcus aureus from pure cultures and naturally contaminated foods. Vogel and Johnson agar was inferior. All colonies exhibiting coagulase activity on BPP were subsequently confirmed as Staph. aureus; this was not the case with presumptive colonies from BP and PCVJ. Based on selectivity, definitive diagnostic characterization of colonies and increased sensitivity (more sample plated), BPP should be considered as the reference method for the routine enumeration of Staph. aureus in foods.
Impact of anticholinergic load of medications on the length of stay of cancer patients in hospice care

An important goal of hospice care is to relieve pain and suffering of terminal cancer patients. Anticholinergic medications are effective in the symptom palliation among terminal cancer patients. However, use of these medications has been associated with increased risk of side effects, which might lead to premature mortality. Short lengths of stay in hospice care leave patients with a higher level of unmet needs. The study was conducted to examine the effect of increasing anticholinergic load on the length of stay of cancer patients in hospice care in the USA.
Solution Stability of Nonsmooth Continuous Systems with Applications to Cone-Constrained Optimization

In this paper we establish conditions for stability, metric regularity, and a pseudo-Lipschitz property of the solution maps of parametric inequality systems involving nonsmooth (not necessarily locally Lipschitz) continuous functions and closed convex sets. We also derive open mapping and inverse mapping theorems for nonsmooth continuous functions, Lagrange multiplier rules for nonsmooth cone-constrained optimization problems, and conditions for the continuity of the optimal value functions of optimization problems. The main tool used is a generalized Jacobian, called approximate Jacobian. It provides a flexible nonsmooth local analysis of continuous functions and often gives sharp calculus rules for locally Lipschitz functions. The regularity condition, which plays a key role in the local analysis, is a new extension of the Robinson regularity condition for continuous functions.
A prospective analysis of the recovery of attention following pediatric head injury

Little is known about specific attentional sequelae following a closed head injury, their pattern of recovery or their interaction with ongoing development. The present study examined attentional abilities in a group of children who had sustained a mild, moderate, or severe head injury. Results showed that the severe head injury group exhibited greater deficits on a number of attentional measures at acute and 6 months postinjury phases, in comparison to children in the mild and moderate head injury groups. Specifically, deficits were most evident on timed tasks where speed of processing was an integral component. Difficulties persisted to at least 6 months postinjury and so may lead to cumulative deficits over time. (JINS, 1999, 5, 48–57.)
REP‐PCR tracking of the origin and spread of airborne Staphylococcus aureus in and around chicken house

Abstract Staphylococcus aureus was used as an indicator to study the origin and spread of microbial aerosol in and around chicken houses. Air samples indoor, upwind (10 and 50 m), and downwind (10, 50, 100, 200, and 400 m) of four chicken houses were collected using Andersen‐6 stages sampler. The concentrations of S. aureus were determined for every sample site. Isolation of S. aureus from chicken feces was performed according to the standard method. The genetic relationship among the isolates was determined by profiles of PCR‐amplified repetitive extragenic palindromic (REP‐PCR) elements. The results showed that the concentrations of S. aureus indoor of four chicken houses were higher than those upwind and downwind sites (P < 0.05 or P < 0.01), but there were no significant concentration differences among downwind sites (P > 0.05). The fingerprints and the phylogenetic tree indicated that a part of the S. aureus (55.6%, 10/18) isolates from indoor air had the same REP‐PCR fingerprints as feces isolates. Consequently, most isolates (57.1%, 20/35) from downwind 10, 50, 100, 200, even 400 m had the same REP‐PCR fingerprints as those from indoor or feces. These data indicated that some isolates from downwind and indoor originated from the chicken feces. However, those isolates from upwind had low similarity (similarity index 0.6–0.87) to those from indoor or feces. Therefore, the isolates upwind were not from the chicken feces or indoor. These results suggest that microbes in chicken feces can be aerosolized and spread indoor and outdoor, especially to downwind of the chicken houses. It should have an important epidemiological and public health significance. Practical Implications Thus, the use of S. aureus as an indicator to study the origin and spread of airborne pathogens from chicken houses is potentially useful for enhancing public health and understanding the airborne epidemiology of this pathogen. Meanwhile it can provide evidence for studying the spreading model of airborne pathogens.
Island Rhythms: The Web of Social Relationships and Interaction Networks in the Lesser Antillean Archipelago between 400 B.C. and A.D. 1492

The precolonial communities of the Caribbean archipelago were not insular. The discontinuous natural resource distribution, the maritime orientation of the Caribbean Amerindians, and the complexities of regional social interaction ensured that the precolonial Caribbean islandscape was dynamic and highly interconnected. This report explores the socicultural behavior and intercommunity exchange relationships of the inhabitants of the Lesser Antilles. It combines related archaeological case studies encompassing the procurement and exchange of: (1) raw materials and utilitarian goods with a wide spatial and social distribution, (2) goods with high stylistic visibility and presumed social function as markers of identity or status, and (3) prestige goods with profound ceremonial value. The study of these objects reveals overarching social and ideological dimensions to Caribbean life. Data suggest that social relationships manifest themselves at different levels and through distinct rhythms while taking on various material guises during the Ceramic age Amerindian occupation of the Caribbean islands (400 B.C. to A.D. 1492). While there is great potential in unraveling interaction networks through the careful study of distribution patterns, the incorporation of ethnohistoric and ethnographic information is imperative to elucidate the web of social relationships underlying these material manifestations.
Amplification of TOP2A and HER-2 genes in breast cancers occurring in patients harbouring BRCA1 germline mutations

BRCA1 associated tumours are found to express an oestrogen receptor negative “basal epithelial-like” phenotype. In contrast to ER negative tumours in general, such tumours rarely harbour amplification of the HER-2 gene. However, little is known about TOP2A gene amplification status in BRCA1-associated tumours. Such information may be of importance to therapy, as amplification of TOP2A has been associated with dose-dependent sensitivity to anthracycline therapy in breast cancer. We examined 40 breast carcinomas from BRCA1 mutation carriers and 40 sporadic breast carcinomas matched for age, tumour diameter and histological grade for HER-2 and TOP2A amplification status using fluorescence in situ hybridisation (FISH). Co-amplification of TOP2A and HER-2 was found in four of the mutation carriers and in three of the controls. While six tumours in the control group harboured HER-2 amplifications with normal TOP2A, this occurred in three of the BRCA1 associated tumours only. In contrast, three of the BRCA1-associated tumours but none of the controls harboured TOP2A amplification despite normal HER-2 status. Our findings have potential therapeutic implications. HER-2 assessment is routinely used to select breast cancer patients for trastuzumab but also dose-intensive anthracycline therapy. Our data suggest that BRCA1-associated breast cancers also need to be tested for TOP2A amplification.
[Clinical manifestations of the mouth revealing Vitamin B12 deficiency before the onset of anemia].

INTRODUCTION The association of manifestations in the mouth and Vitamin B12 deficiency is already known. The signs are not specific to Vitamin B12 deficiency, however they may reveal the deficiency and this is often ignored and leads to delays in diagnosis. We report two cases of Vitamin B12 deficiency revealed by stomatodynia, glossitis and erosions in the mouth. OBSERVATIONS Two women aged 51 and 76 years consulted, one for atrophic glossitis and the other for stomatodynia that had progressed over the past few months. No other symptoms were present. The biological examinations revealed isolated macrocytosis without anemia. Vitamin B12 could not be measured in the serum. The symptoms regressed in less than one month following replacement therapy. DISCUSSION As with our two patients, the majority of cases of Vitamin B12 deficiency reported in the literature were only discovered several months or years after their onset, or were treated for other causes. Vitamin B12 deficiency leads to severe neuropathies. The neurological damage is reversible when replacement therapy is initiated early. Since the oral signs appear before the modification in the systemic markers of deficiency, it is crucial that these signs be recognized and diagnosed before the occurrence of severe after effects.
Nitrogen, Phosphorus, Potassium, Magnesium and Calcium Removal by Brown Midrib Sorghum Sudangrass in the Northeastern USA

For the long-term sustainability of the dairy industry in the Northeastern USA, manure nutrient application rates should not exceed crop nutrient removal once aboveoptimum soil fertility levels are reached. Dairy producers have shown a growing interest in brown midrib (BMR) forage sorghum (Sorghum bicolor (L.) Moench. ) · sudangrass (Sorghum sudanense Piper) hybrids (S · S) as a more environmentally sound alternative to maize (Zea mays L.) but data on S · S nutrient removal rates are scant. Our objectives were to determine N, P, K, Ca and Mg removal with harvest as impacted by N application rate, using six N rate studies in New York. One of the six sites had a recent manure history. Although site-to-site differences existed, N application tended to decrease P and K and increase N, Ca and Mg concentrations in BMR S · S forage. Nutrient removal and yield were highly correlated for all sites except one location that showed a K deficiency. The crop removed large amounts of P and K in the manured site, suggesting that BMR S · S is an excellent scavenger of these nutrients. If manure is applied mid-season, forage K levels are likely too high for feeding to non-lactating cows.
Correlación de la productividad de un forraje con las propiedades físicas de un Ultisol en Aquidauana

Los sistemas de produccion de ganaderia y de manejo de pastos alteran las propiedades fisicas del suelo, reflejados en la productividad y la composicion vegetal. El objetivo de este trabajo fue indicar las propiedades fisicas del suelo con mejores correlaciones lineales y espaciales para obtener sitios especificos de manejo del suelo. Se analizaron las correlaciones lineales y espaciales entre la productividad de la materia seca del forraje de Brachiaria decumbens (Stapf) y algunas propiedades fisicas de un Ultisol en dos profundidades (0,00-0,10 m y 0,10-0,20 m). Para la colecta de los datos fue instalada una red geoestadistica con 121 puntos de muestreo. La productividad del forraje vario aleatoriamente y no siguio patrones espaciales, presentando el efecto pepita puro. La resistencia mecanica del suelo a la penetracion y la humedad del suelo en la capa de 0,10-0,20 m, son importantes indicadores de la calidad fisica del suelo. El aumento de estas propiedades en el cultivo del forraje, promovio la reduccion de la materia seca del forraje. Por lo tanto, estos indicadores representan confiabilidad para estimar la productividad del forraje.
New medicines in primary care: a review of influences on general practitioner prescribing

Background and objective: The uptake of new medicines is slower in the UK than in many other countries. Previous research found that cost and price have little influence on general practitioner (GP) behaviour, but recent UK government policy may have heightened cost‐consciousness. Focussing on new medicines, this review aimed to explore the determinants of uptake, the causes of geographical variations, and the influence of price, cost and financial incentives on prescribing behaviour.
A latent growth curve modeling approach using an accelerated longitudinal design: the ontogeny of boys' and girls' talent perceptions and intrinsic values through adolescence

This article presents latent growth modeling, a particular application of multilevel modeling, to examine the development of adolescents' math- and English-related talent perceptions and intrinsic values which are emphasized by Expectancy-Value theory as important precursors to a range of achievement-related outcomes. The longitudinal cohort-sequential study included participants in 3 overlapping cohorts, together spanning Grades 7 to 11 (N = 1,323). In this paper, I focus on the application of latent growth curve modeling to the accelerated longitudinal design and the interpretation of the growth parameters and their correlates in evaluating students' developmental trajectories across 2 key academic domains. Talent perceptions and intrinsic values were found to decline through adolescence in both math and English, and gender differences favored boys for math and girls for English consistent with gender stereotypes.
A case of primary gastric lymphoma in a patient with thalassemia major

A 37-year-old female with thalassemia major, genotype IVS106/b8 – 39, was on a regular transfusion schedule since 6 months of age in order to maintain a hemoglobin concentration of 9 – 10 gr/dl. Splenectomy and cholecystectomy were performed at ages 14 and 20 years, respectively. Her serum ferritin level was known to fluctuate between 1500 – 1800 ng/ml and she had received chelation therapy with Deferoxamine since 1977. Echocardiography was within normal limits with an ejection fraction of 65 – 70%. She was found to be seronegative for Hepatitis C and HIV, and had been immunized for Hepatitis B and meningococcus. Her growth parameters were normal, but she had mild osteopenia on DEXA scan. Routine evaluation for hemosiderosis with T2 weighted MRI revealed an increased iron deposition in liver [ln(SD/ SI)1⁄4 1,9] and a normal in the heart [ln(SD/SI)1⁄4 3,3]. The patient agreed to supplement her chelation therapy with oral Deferiprone (75 mg/kg/day). After two months of therapy, she began to complain of intense stomach pain, nausea and vomiting. As the patient had a known history of peptic ulcer disease, the Deferiprone therapy was held and she was started on triple therapy of clarithromycin, amoxicillin and omeprazole and showed improvement. Several months later, she was restarted on oral chelation therapy and presented again several weeks later with nausea, epigastric pain and a 5 kg weight loss secondary to anorexia. Laboratory testing revealed WBC 19610/L (65% poly, 25% lymph, 15% erythroblasts), Hb 9 gr/dl, and platelets 670610/L. Chemistries were within normal limits, except for an elevated LDH (273 Ul/l) due to chronic haemolysis. Gastrointestinal endoscopy demonstrated a large, irregular ulcer and pyloric stenosis (Figure 1), with a negative clo-test. Biopsy of the gastric mucosa showed diffuse large B cell lymphoma of mucosa-associated lymphoid tissue (CD 20þ , CD45RAþ), which was associated with chronic gastritis and findings of haemosiderosis. Helicobacter pylori was not found in biopsy, with haematoxylin stain. Computerized tomography of the chest, abdomen and pelvis showed enlarged epigastric lymph nodes. Bone marrow examination and karyotypic analysis were normal. The stage of disease was IIE1, according to Musshof et al. staging
Correlates of vigorous exercise in a predominantly low SES and minority high school population.

BACKGROUND This study identifies correlates of vigorous exercise among minority and low-socioeconomic-status adolescents. METHODS Ninth and 11th grade students completed 1,634 questionnaires regarding vigorous exercise and possible correlates. RESULTS While 76% of students participated in vigorous exercise 3 or more times per week (the year 2000 goal for the nation), only 55% participated in vigorous exercise 3 or more times per week outside of school. A substantial minority of students (20%) did not participate in any vigorous exercise outside of school, and 11% did not participate in any vigorous exercise at all. Males and 9th graders participated in significantly more vigorous exercise than did females and 11th graders both in school physical education and outside of school. Hierarchical multiple regression analyses with 28 independent variables were computed separately for males (R = 0.44, F(28,625) = 5.27, P < 0.001) and females (R = 0.45, F(28,622) = 5.56, P < 0.001). Correlates were similar for both groups and included self-efficacy, family, and friend support. CONCLUSIONS Results suggest that among minority and lower socioeconomic status adolescents the prevalence of vigorous exercise decreases with age or when students are not required to participate in school physical education and that social factors may be instrumental for sustaining vigorous exercise.
Incidence of numerical chromosome aberrations in meningioma tumors as revealed by fluorescence in situ hybridization using 10 chromosome-specific probes.

OBJECTIVE Although information on the cytogenetic characteristics of meningioma tumors has accumulated progressively over the past few decades, information on the genetic heterogeneity of meningiomas is still scanty. The aim of the present study was to analyze by interphase fluorescence in situ hybridization (FISH) the incidence of numerical abnormalities for chromosomes 1, 9, 10, 11, 14, 15, 17, 22, X, and Y in a group of 70 consecutive meningioma tumors. Another goal was to establish the potential associations among the altered chromosomes, as a way to assess both intertumoral and intratumoral heterogeneity. METHODS For the purpose of the study, 70 patients diagnosed with meningioma were analyzed. Interphase FISH for the detection of numerical abnormalities for chromosomes 1, 9, 10, 11, 14, 15, 17, 22, X, and Y was applied to fresh tumor samples from each of the patients studied. RESULTS The overall incidence of numerical abnormalities was 76%. Chromosome Y in males and chromosome 22 in the whole series were the most common abnormalities (46% and 61%, respectively). Despite the finding that monosomy of chromosome 22/22q(-) deletions are the most frequent individual abnormality (53%), we have observed that chromosome gains are significantly more common than chromosome losses (60% versus 40%). Chromosome gains corresponded to abnormalities of chromosomes 1 (27%), 9 (25%), 10 (23%), 11 (22%), 14 (33%), 15 (22%), 17 (23%), and X in females (35%) and males (23%) whereas chromosome losses apart from chromosome 22 frequently involved chromosomes 14 (19%), X in males (23%), and Y in males (32%). Although an association was found among most gained chromosomes on one side and chromosome losses on the other side, different association patterns were observed. Furthermore, in the latter group, monosomy 22/22q(-) was associated with monosomy X in females and monosomy 14/14q(-) was associated with nulisomy Y in males. In addition, chromosome losses usually involved a large proportion of the tumor cells whereas chromosome gains were restricted to small tumor cell clones, including tetraploid cells. CONCLUSIONS Our results show that meningiomas are genetically heterogeneous tumors that display different patterns of numerical chromosome changes, as assessed by interphase FISH.