Miracle-dz/UniFAR-FTUs huggingface dataset:
High expression of class III β-tubulin in upper gastrointestinal cancer types

Class III β-tubulin (TUBB3) is a component of microtubules of neuronal cells that is upregulated in various cancer entities. To better understand the role of TUBB3 in upper gastrointestinal tract cancer types, the present study assessed TUBB3 expression in tissue microarrays including 189 gastric and 428 esophageal cancer. TUBB3 expression was detected in 62.4% of gastric cancer, 73.8% of esophageal adenocarcinoma and 88.7% of esophageal squamous cell cancer, while control samples of normal esophageal and gastric epithelium were TUBB3-negative. TUBB3 positivity was not associated with the International Union Against Cancer classification, World Health Organization grading, lymph node involvement or distant metastasis in any entity. Of note, TUBB3 expression was associated with tumor localization and prognosis in gastric cancer, with the tumor stage in esophageal adenocarcinoma, and with the resection margin in esophageal squamous cell cancer. In conclusion, the substantial rate of positivity for TUBB3 already in early stages of gastric cancer in combination with the lack of a further increase in frequency with tumor stage, may suggest, that TUBB3 upregulation is rather relevant for cancer development than for cancer progression. TUBB3 might be a suitable prognostic biomarker in gastric cancer types.
Isotopically modified Ge detectors for GERDA: from production to operation

The GERDA experiment searches for the neutrinoless double beta (0νββ) decay of 76Ge using high-purity germanium detectors made of material enriched in 76Ge. For Phase II of the experiment a sensitivity for the half life T1/20ν ~ 2·1026 yr is envisioned. Modified Broad Energy Germanium detectors (BEGe) with thick n+ electrodes provide the capability to efficiently identify and reject background events, while keeping a large acceptance for the 0νββ-decay signal through novel pulse-shape discrimination (PSD) techniques. The viability of producing thick-window BEGe-type detectors for the GERDA experiment is demonstrated by testing all the production steps from the procurement of isotopically modified germanium up to working BEGe detectors. Comprehensive testing of the spectroscopic as well as PSD performance of the GERDA Phase II prototype BEGe detectors proved that the properties of these detectors are identical to those produced previously from natural germanium material following the standard production line of the manufacturer. Furthermore, the production of BEGe detectors from a limited amount of isotopically modified germanium served to optimize the production, in order to maximize the overall detector mass yield. The results of this test campaign provided direct input for the subsequent production of the enriched germanium detectors.
Memorandum : UCPRC-TM-2008-14 Calibration of CalME Models Using Field Data Collected from US 101 near Redwood National Park , Humboldt County Author :

CalME is a software package under development for Caltrans that includes mechanistic-empirical response and performance models intended for the analysis and design of asphalt pavement structures. Building on existing design methods, CalME provides an Incremental-Recursive Mechanistic-Empirical (IRME) method in which the materials properties for the pavement are updated in terms of damage as the simulation of the pavement life progresses. The IRME design method incorporates various mathematical models to describe material behavior and predict structure performance. These models need to be calibrated before they can be used to evaluate the performance of different flexible pavement structures. Using data collected from two sites on US 101 near Redwood National Park in Humboldt County, California, this technical memorandum focuses on calibration of the incremental-recursive fatigue cracking model used in CalME. Fatigue shift factors of 0.075 for deterministic analysis and 0.13 for probabilistic analysis (Monte Carlo simulation) were found to best match the actual performance for the US 101 sites. These factors are quite different from those determined using accelerated pavement testing data from the WesTrack closed-circuit track and the Heavy Vehicle Simulator. More calibration studies are recommended.
The patterns of sexuality and the classification of serranid fishes. American Museum novitates ; no. 2207

Classification of the family Serranidae is notoriously unsatisfactory, largely because the serranids and their allies are generalized perciform fishes and the assignment of genera to this complex is often based on the absence of recognized specializations rather than on the presence of basic similarities. Consequently there is little agreement as to the limits of the family, and arrangements within the family are also unsatisfactory. Many serranids, however, are specialized in their reproductive mechanisms and have structural and functional patterns of sexuality that can be utilized in phylogenetic studies. Some species have separate sexes, others are synchronous hermaphrodites that can produce eggs and sperm at the same time, and still others are protogynous hermaphrodites in which the male tissue develops after the female tissue has ceased to function. Moreover, the testes of gonochoristic species differ in structure from those of hermaphroditic forms, and there are several distinct arrangements of ovarian and testicular elements in hermaphroditic gonads. The present paper describes the general structure of the serranid gonads that exhibit three types of hermaphroditism. As more species are studied, it is expected that additional patterns will be found.
Asymmetric covariance in spot‐futures markets

This article studies how the spot‐futures conditional covariance matrix responds to positive and negative innovations. The main results of the article are achieved by obtaining the Volatility Impulse Response Function (VIRF) for asymmetric multivariate GARCH structures, extending Lin (1997) findings for symmetric GARCH models. This theoretical result is general and can be applied to analyze covariance dynamics in any financial system. After testing how multivariate GARCH models clean up volatility asymmetries, the Asymmetric VIRF is computed for the Spanish stock index IBEX‐35 and its futures contract. The empirical results indicate that the spot‐futures variance system is more sensitive to negative than positive shocks, and that spot volatility shocks have much more impact on futures volatility than vice versa. Additionally, evidence is obtained showing that optimal hedge ratios are insensitive to the well‐known asymmetric volatility behavior in stock markets. © 2003 Wiley Periodicals, Inc. Jrl Fut Mark 23:1019–1046, 2003
Sedentary Behaviour and Mental Health in Children and Adolescents: AMeta-analysis

Background: A growing body of research is emerging examining the associations between sedentary behaviour and mental health in young people. The magnitude of the impact sedentary behaviour has on the mental health of young people has not been examined, though this has been investigated for physical health conditions. The aim of this article is to examine the associations between sedentary behaviour and mental health in young people aged 5-18 years of age using meta-analysis. Methods: Published studies in the English language were located via manual and computerised searches of PubMed, Science Direct, SPORTDiscus, PsychINFO, Medline, Web of Science, Cochrane Library, and Google Scholar databases. Included were observational studies assessing an association between at least one sedentary behaviour and at least one aspect of mental health in young people aged 5-18 years. Effect sizes (ESs) were calculated for each study and an overall effect size was computed. Average effect sizes were also calculated for moderator variables. Results: Thirty-five studies were included (n=373,512); most studies examined screen-time as sedentary behaviour and five mental health outcomes were identified (depression, anxiety, self-esteem, psychological distress, and quality of life). The summary effect was small and significant (ES = -0.30, 95% confidence intervals = -0.20, -0.45, p<0.001), suggesting that sedentary behaviour is negatively associated with mental health in young people. Moderator analysis showed that television viewing had the largest effect size (ES = -0.47, 95% confidence intervals = -0.35, -0.62, p<0.001). Moreover, depression seems to be the main mental health outcome affected by sedentary behaviour (ES = 0.55, 95% confidence intervals = 0.42, 0.68, p<0.001). Conclusions: There was a small but a significant negative association between sedentary behaviour and mental health. High levels of sedentary behaviour are associated with increased depressive symptoms. This finding is consistent with a systematic review on adults which indicated that sedentary behaviour is significantly associated with mental health problems.
Multidrug Resistant Proteus mirabilis Isolated from Urinary Tract Infection from Different Hospitals in Baghdad City

A Urinary tract infection can occur anywhere along the Urinary tract. It includes urethritis, cystitis, pyelonephritis, epidydimitis, prostatitis, perinephritis, and abscess and considered one among the most common infectious diseases is widely seen among all age groups of individuals. However some groups of people are more prone to UTI than others. For example there is a higher risk to develop UTI in diabetic patients (Chen et al., 2009). Females have fourteen times more chance to develop UTI than men.The differences are attributed to involvement of several factors. Such as they has a shorter urethra compare to men which open nearer to the anus so that the lower third of urethra is continually contaminated International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 5 Number 9 (2016) pp. 390-399 Journal homepage: http://www.ijcmas. com
Influence of reservoir geometry and conditions on the seismic response of arch dams

An analysis of the influence that reservoir levels and bottom sediment properties (especially on the degree of saturation) have on the dynamic response of arch dams is carried out. For this purpose, a Boundary Element Model developed by the authors that allows the direct dynamic study of problems that incorporate scalar (dammed up water), viscoelastic (dam and soil site) and poroelastic media (bottom sediments in the reservoir) is used. All of the regions are discretized using boundary elements, later formulating equations of compatibility and equilibrium that allow their interaction to be rigorously established. The seismic excitation consists in plane longitudinal waves (P waves) and shear waves (S waves) impinging the dam site with an angle of vertical incidence. The analysis is carried out in the frequency domain, and the time response is obtained, for synthesized artificial accelerograms defined in terms of the elastic response spectrum taken from Eurocode 8, using a FFT algorithm. The variables used to characterize the response are: Amplitude of the complex-valued frequency-response function, acceleration response spectra and the integral of velocity of points located at the structure. These variables clearly indicate the importance that the factors analyzed have on the dynamic response.
Leonardite and Fertilizer Levels Influence Tomato Seedling Growth

New Mexico-mined raw leonardite was characterized by comparing it with the International Humic Substances Society's Standard Leonardite. In the first experiment, adding as little as 1/64 leonardite (v/v) to a sand medium increased tomato (Lycopersicon esculentum (L.) Mill. 'Mountain Pride') root and shoot growth compared with plants produced with fertilizer alone. Growth increased linearly with increasing leonardite levels, from 0% to 25%; however, 50% leonardite inhibited growth. In a second experi- ment, leonardite alone had no effect on plant height, shoot or root fresh and dry weight, or total leaf area, but stimulated growth when combined with a complete fertilizer. Adding 1/3 leonardite (v/v) (the highest level) and a complete fertilizer increased plant height 40%, total leaf area 160%, shoot fresh weight 134%, root fresh weight 82%, shoot dry weight 133%, and root dry weight 400%.
Aggressive Tax Strategies and Corporate Tax Governance: an Institutional Approach

This paper deals with the impact of tax-aggressive strategies on corporate governance by adopting an agency perspective of the firm and discusses how certain corporate tax governance measures may limit these kinds of managerial actions. The paper defines the regulative concept of effective tax planning as a tax strategy that minimizes not only explicit taxes, but also implicit taxes and non-tax costs, focusing on the agency problems emerging between shareholders and tax managers. This key concept is then used to identify what kind of tax-aggressive strategies pose relevant policy issues and to highlight important issues, such as: why and to what extent do managers pursue aggressive tax strategies, why are these strategies used in large companies, do these strategies advance shareholder value, and how can tax savings obtained through these strategies be measured? The conclusion os that aggressive managerial tax behaviour requires counterbalancing policies which are not limited to the traditional anti-avoidance rules but also include the tools of corporate tax governance; such as risk and metarisk management, disclosure rules, regulation of tax advisors, reporting
Assessment of the Large Mammals of Arakhuan Range, Okomu National Park, Nigeria

An assessment of the large mammals of Arakhuan Range, Okomu National Park, Edo State, Nigeria, was carried out using land transect methods. A total of 12 large mammalian species were observed (eight directly and four by their signs). These are made up of four primate species; Red-capped mangabey ( Cercocebus torquatus ), Mona monkey ( Cercopithecus mona ), White-throated monkey ( C. erythrogaster pocok i), and Putty-nosed monkey ( C. nictitans ludio ), three species of antelope: Maxwell duiker ( Cephalophus maxwelli ), Yellow-backed duiker ( Cephalophus silvicultor ), and Red-flanked duiker ( Cephalophus rufilatus ), and a species of mangoose ( Herpestes sp). Those observed through their activities were forest elephants ( Loxodonta africana cylotis ), forest buffalo ( Syncerus caffer nanus ), civet cat ( Viverra civetta ) and the red river hog ( Patamochoerus porcus ). Altogether, 145 sightings of animals were recorded during the study period. Mona monkeys were most commonly sighted (sighted 37 times, producing 0.22 sighting/km) -2 and population of 1970.93±412.93 individuals. The yellow-backed duiker was very rare in the range as it was sighted three times with an estimated population of 9 ± 2 individuals. There is very strong correlation between sightings in the morning and that of evening (r = 0.94, P < 0.05). However, there were significant differences in sighting on transects (χ2 cal. = 35.18, χ2 tab. = 32.7, df = 10, P < 0.05) indicating that sightings are transect-dependent. Over 50% of all sightings were achieved in the matured forest. Keywords: Mammals, line transect, sightings, estimated population.
Natural pedagogy and social interaction

I briefly review several debates between standard cognitivist theories and more embodied (and enactive) theories in the area of social cognition, especially in the context of developmental studies and recent falsebelief experiments with young infants. I suggest that the concept of natural pedagogy (Csibra & Gergely, 2009) fits best with the more embodied and enactive accounts of social cognition, and that it provides a good model for an embodied learning process
SECTORAL FOREIGN AID AND INCOME INEQUALITY

This study contributes to the empirical understanding of foreign aid and income inequality by investigating the effect of foreign aid on income inequality in recipient countries, based on the disaggregation of foreign aid figures. For this purpose we include four main sectoral foreign aid (social sector, economic sector, production sector and multi sector) as determinants of income inequality. This study utilized the Generalized Method of Moments (GMM) method for a panel of 75 foreign aid recipient countries covering the period of 1995-2009. The results indicated that different sectoral foreign aid affected income inequality differently. Aid to economic sector has significant impact in reducing income inequality. In contrast, aid to multi sector significantly increased income inequality.
The Contribution of Managers to Organizational Success

We study the impact of managers on the success of professional soccer teams using data from the German Bundesliga, where we are exploiting the high turnover rate of managers between teams to disentangle the managers’ contributions. Teams employing a manager from the top of the ability distribution gain on average considerably more points than those employing a manager from the bottom. Moreover, estimated abilities have significant predictive power for future performance. Managers also affect teams’ playing style. Finally, teams whose manager has been a former professional player perform worse on average compared to managers without a professional player career.
Existence of Critical Aggregation Concentration at the Very Dilute Regime of Poly(vinylidene fluoride)/Propylene Carbonate System

Poly(vinylidene fluoride), Critical aggregation solution, Core-shell, Light scatteringSince poly(vinylidene fluoride) (PVDF) has been knownas a typical semicrystalline polymer with strong piezo-electric and pyroelectric properties, lots of scientificresearches have been focused on these topics. In addition,recently, thermoreversible physical gelation
THE DENSITY OF DISCRIMINANTS OF S3-SEXTIC NUMBER FIELDS

We prove an asymptotic formula for the number of sextic number fields with Galois group S 3 and absolute discriminant < X. In addition, we give an interpretation of the constant in the formula in terms of the asymptotic densities of given local completions among these sextic fields. Our proof gives analogous results when we count S 3 -sextic extensions of any number field, and also when finitely many local completions have been specified for the sextic extensions.
On quasiconformal self-mappings of the unit disk satisfying Poisson’s equation

Let QC(K, g) be a family of K-quasiconformal mappings of the open unit disk onto itself satisfying the PDE Δw = g, g ∈ C(U), w(0) = 0. It is proved that QC(K,g) is a uniformly Lipschitz family. Moreover, if |g| ∞ is small enough, then the family is uniformly bi-Lipschitz. The estimations are asymptotically sharp as K → 1 and |g| ∞ → 0, so w ∈ QC(K, g) behaves almost like a rotation for sufficiently small K and |g| ∞ .
Regularization in PNAH by means of L-curve

Planar Near-field Acoustic Holography (PNAH) is an acoustic imaging technique based on the inverse solution of the wave equation. Planar acoustic information at a certain distance from the source of interest, known as the hologram, is used as input to signal process based on Fourier transforms understrict boundary conditions. In the so-called wavenumber domain one of the most influential steps on the end result is the two-dimensional low-pass filter. Especially for high resolution PNAH the determination of the filter cut-off is crucial. The low-pass filter cut-off wavenumber serves as the regularization parameter in the inverse and ill-posed process. An increasingly higher cut-off wavenumber results in a"blow up" of the inverse solution, which is a property of an ill-posed problem. On the other hand, lower cut-off wavenumbers result in spatial acoustic data at very low resolution, where highly detailed information is discarded. Thus, it is desired to obtain an optimal solution for the cut-off wavenumber somewhere in between, which is basically a trade-off between noise being blown-up and useful information being discarded. This paper introduces a regularization technique to obtain the optimal filter cut-off by means of the L-curve. Fast and efficient post-processing techniques are explained and illustrated by a practical case.
Industrial development, agricultural growth, urbanization and environmental Kuznets curve in Pakistan

The debate of environmental issues and their analysis is of vital interest for economic policies. Institutions are engaged in identifying and estimating the extent of environmental impact of determinants controllable via policy measures. Annual data from the on Carbon Dioxide emission, economic growth, consumption of energy, openness for foreign trade, urbanization, industrial growth and agriculture growth on Pakistan is used for 1971 to 2007. Augmented Vector Autoregression technique and cointegration analysis is implemented to test Granger causality. Gross domestic product significantly Granger causes emission of Carbon Dioxide and energy consumption. On the other hand emissions of CO2 affect economic growth, agriculture and industrial growth in the long run. It is also evident that energy consumption unidirectional Granger causes emission of Carbon Dioxide. Industrialization and urbanization bidirectional Granger causes each other. The results indicate the more careful industrial and energy policies to reduce emissions and control global warming.
Changes in teacher self-efficacy in the first year of primary school teacher education study

The beginning phase of teaching is a time of flux in the self-efficacy beliefs held by teachers. Little is known, however, about the exact peaks and troughs that beginning teachers experience. While it is theorized that teacher self-efficacy increases during teacher education and declines during the beginning months of teaching (Tschannen-Moran and Woolfolk Hoy, 2007), little is known specifically about the changes during the period of engagement in teacher education programs. This paper reports on the first stages of a longitudinal study that sets out to explore pre-service teacher self-efficacy as students journey through their four-year program of study. It reports on initial levels of self-efficacy in the first week of entering a teacher education program and the changes after completion of one year of the degree. Findings are important as they provide insights for teacher educators and institutions to support the development of positive teacher self-efficacy beliefs.
Guttation and risk for honey bee colonies ( Apis mellifera L.): Use of guttation drops by honey bees after migration of colonies - a field study

Background: The aim of this experiment was to investigate whether honeybees from colonies that are not familiar with their surrounding landscape, due to short-distance migration to a new location, are more at risk by guttation drops from seed-treated plants than bee colonies which are already familiar with alternative water sources in the surrounding of their apiary. Results: The mean mortality of bees, which occurred after moving beehives to a new location, increased only slightly from 6 bees/day (-1 day before moving) up to a maximum of 21 bees/day (1 day after moving). No significant differences in the mean number of dead bees between bee colonies that were familiar with all sites of water sources in the surrounding area and bee colonies that were only recently moved to the field were observed. Conclusion: There was no indication that honey bee colonies which were not familiar with the surrounding landscape are more at risk by guttation drops from seed-treated plants than bee colonies which are already familiar with the alternative water sources in their surrounding landscape. Keywords: guttation, seed treatments, transport beehives, pesticides, honey bee, water foragers
DETERMINANTS OF SOIL NUTRIENT BALANCES AND IMPLICATIONS FOR ADDRESSING LAND DEGRADATION AND POVERTY IN UGANDA

A regression model was used to investigate the determinants of soil nutrient depletion in Uganda. The major determinants of soil nutrient balances are household endowments, access to markets, and extension services, non-farm activities and agricultural potential. The results suggest the need to address soil nutrient depletion using multi-sectoral approaches.