Miracle-dz/UniFAR-FTUs huggingface dataset:
Trend & Pattern of Dengue cases in a Tertiary Care Hospital in Pune, Maharashtra

Original Research Article Dengue virus is a mosquito-borne flavivirus and one of the most prevalent arbovirus in tropical and subtropical regions of the world. Dengue virus infection has emerged as notable public health problem in recent decades especially in the tropical and subtropical countries because of high mortality and morbidity associated with it. The study was performed in the record department of Medical College & Hospital, pune over a period of three years (From January 2014 to December 2016) with2490 clinically suspected patients attending the hospital & suffering from fever for at least five days. Blood was collected aseptically from suspected cases, serum was separated and analyzed by IgM capture ELISA technique to detect Dengue specific IgM antibodies. In this study, the highest numbers of cases (57.31%) were recorded in the age group 10–29 yrs with male preponderance and majority belonging to urban area. In present study the positivity rate of the dengue positive cases were decreasing over study period from 24.04% to 11.92%. A seasonal variation is also observed as there is an increasing no. of cases from July onward i.e. monsoon period in months from August to November. The no. of cases started rising from August and peaks at October, during all three years of the study. Community awareness, early diagnosis and management and vector control measures need to be strengthened in order to reduce the increasing number of dengue cases. Special preventive strategies should be planned during post monsoon period. Every case of fever should visit physician immediately to prevent complications, in rural as well as urban areas.
Evaluation of Highly Realistic Training for Navy Corpsmen: Results for Field Medical Training Battalion-West

Abstract : In this study, a sample of corpsmen students attending Field Medical Training Battalion West (FMTB West) participated in highly realistic training. The objectives of this study were to (1) assess the corpsmen participants satisfaction with highly realistic training, and (2) assess the impact of highly realistic training on participants self-efficacy (i.e., confidence), perceived readiness, and career intentions. Corpsmen participants expressed high levels of satisfaction with the training overall and with specific elements of the training. The aspect of the training that was rated highest by participants was the use of live actors. Comparisons of pretest and posttest survey responses revealed that the training produced significant increases in participants levels of general, occupational, and task-specific self-efficacy, as well as their perceived readiness. Overall, these results suggest that highly realistic training is a useful and effective method for training corpsmen. It is suggested that highly realistic training be extended to other populations of military medical providers.
THE EFFECTIVENESS OF CERVICAL CANCER SCREENING IN WOMEN TARGET GROUPS BY SUB-DISTRICT HEALTH PERSONNEL IN CONTRACTING UNIT PRIMARY CARE NETWORK OF NONGBUALUMPHU MAUNG DISTRICT

The objectives of this survey research were to evaluate the effectiv n ess of cervical cancer screening in women target groups by 63 sub-district health personnel in contracting unit primary care network of nongbualumphu maung district and to explain the relationship between personal factor,knowledge about screening, attitude towards working,management resources and administration process. The data collection was done by using a questionnaire.The co ll ected data was analyzed by mean of percentage,arithmetic mean,standard deviation,maximum value, minimum value, Chi-square Test and Pearson , s Product Moment Correlation Coefficient with the level of statistic significance ( a ) = 0.05. The results showed that the effectiveness of cervical screening in women target groups by sub- district health personnel in contrating unit primary care network of nongbualumphu maung district feel at a level that required some improvement at 56.86 % ,kwonledge sub-district health personnel about cervical cancer screening was low at 90.2 % attitude towards this screening work was good at 74.56 % After analyzing the relationship between peronnal factor, e.g. gender,age,marriage status,level of education,present job title,income,working experience and training experience and training experience,it was found that these factors were not related to the effectiveness of cervical cancer screening in women target groups. In regard to the manpower factor and tool eguipment factor ,it was found that it was sinificantly related to the effectiveness of cervical cancer screening in women target groups at a statistic test level ( P= 0. 009 ) and ( p=0.017 ). The financial factor were not related to the effectiveness of cervical cancer screening in women target groups.In addition, the administration process was not related to the effectiveness of cervical screening in women target groups. The suggestion of this study is that health personnel competency should be developed in term of Knowledge, skills, techniques and methods of cervical cancer screening to enhance quality and to ensure accurate and constant screening . Executives should give strong support to the workforce so that personnel, tool eguipment are adequate and appropriate for this work.
Journey to the Doctorate:The Experiences of First-Generation HIspanic Students

Journey to a Doctorate: The Experiences of First-Generation Hispanic Students. (August 2012) Mary Lou Gonzalez, B.B.A., Texas A&M University-Kingsville; M.S., Texas A& M University-Kingsville Chair of Advisory Committee: Dr. Jia Wang The purpose of this study was to understand the lived experiences of firstgeneration Hispanic students who have obtained a doctorate degree (EdD or PhD). The Hispanic population continues to increase in the United States, particularly in the state of Texas. However, the level of Hispanics’ educational attainment lags behind that of the U.S. and Texas populations in general. The overall economic impact of low Hispanic educational attainment, coupled with continuing growth of this group, presents a pressing issue for future workforce educators and human resource development professionals. It is critical to understand educational experiences of first-generation Hispanic students to address the lack of educational achievement among this group of people. Within the naturalistic inquiry research paradigm, I adopted a hermeneutic phenomenological approach to collect rich and thick data that could shed light on the “lived experiences” of six doctoral recipients who are first-generation Hispanic students. Through multiple rounds of in-depth interviews, supplemented by personal observations and multiple email exchanges with participants, I generated extensive personal stories, developed a meaningful relationship with the participants, and discovered the essence of the participants’ experiences. Four themes emerged from an in-depth analysis of
Biomarkers of kidney and liver toxicity in male Sprague-Dawley rats following fourteen day oral exposure to methyl tertiary-butyl ether

OF THE THESIS Biomarkers of Kidney and Liver Toxicity in Male SpragueDawley Rats Following Fourteen Day Oral Exposure to Methyl Tertiary-Butyl Ether by Shannon Elyse Barceloux Master of Science in Public Health San Diego State University, 2010 Methyl tertiary-butyl ether (MTBE) is a gasoline oxygenate blended into fuel formulas in the 1990s to decrease carbon monoxide emissions. Although MTBE was banned from use as a fuel additive in 2006, it has been detected in public drinking water in several states throughout the country and elsewhere in the world. Now the EPA must regulate MTBE contamination in ground and surface waters. Although the health risk of human exposure to low doses of MTBE is unknown, long-term rodent cancer bioassays using high concentrations of MTBE increases the incidence of tumors at various organ sites. The two studies presented in this thesis are the latest in a series of experiments at this university designed to better understand how MTBE causes an increase in endocrine-related tumors. The research from the first experiment reported here focuses on the incorporation of more standardized measures of generalized toxicity (e.g., stress response) that are very important for understanding the MTBE-related endocrinological changes in relation to the broader toxicological perspective. Previous studies also demonstrate MTBE-induced renal damage in the proximal tubules of male rats through interaction with α-2u-globulin. A second study explores the use of novel urinary proteins as biomarkers of renal damage induced by MTBE exposure. In the first experiment (n=16) Sprague-Dawley male rats were gavaged with 0 (corn oil), 600 or 1200 mg/kg MTBE per day for 14 consecutive days. In the second experiment (n=5) Sprague-Dawley male rats were gavaged with 0 (corn oil) or 1200 mg/kg MTBE per day for 14 consecutive days. Serum corticosterone concentrations were measured in the first study and showed a significant increase (p<0.05) in the 1200 mg/kg MTBE treated group. Hepatorenal serum chemistry was measured in both studies and revealed no differences between treated and control animals. However, in the second study two of the six urinary protein concentrations (β-2-microglobulin and cystatin C) displayed significant increases (p<0.05) in the 1200 mg/kg MTBE treated group relative to the control group. Therefore, urinary protein concentrations proved to be more sensitive biomarkers of renal changes than conventional serum chemistry (BUN and creatinine) following subchronic high dose oral MTBE exposure. Although MTBE induced endocrine change has been the focus of previous experiments, the two current studies reveal other exposure related systemic changes that could also affect alteration in endocrine function.
Intensive Care Management of Thoracic Aortic Surgical Patients, Including Thoracic and Infradiaphragmatic Endovascular Repair (EVAR/TEVAR)

The patient with thoracic aortic disease can present for open or endovascular repair. Thoracic endovascular aortic repair (TEVAR) has emerged as a minimally invasive option for a multitude of aortic pathology, including dissections, aneurysms, traumatic injuries, and ulcers. Postoperative management of these patients depends on the extent of procedure, whether it was open or endovascular, and, finally, on the preoperative comorbidities present. While procedural success has catapulted TEVAR to popularity, midterm results have been mixed. Additionally, periprocedural complications such as paraplegia and renal failure remain a significant morbidity in these patients.
Preventing Weight Gain Among Coeds: The Need for Web-Based and Tailored Approaches

It is during the traditional college years that many young people move away from a structured and supportive home environment to a situation where multiple demands must be negotiated independently for the fi rst time. Abstract: College students experience numerous challenges as they assume novel responsibilities and choices associated with residing on campus. Although the transition away from home and parents is associated with weight gain, sedentary behavior, and less-nutritious diets, few obesity prevention studies have targeted college adults. Because of their familiarity with the Internet, college-age adults (18-24) may be more receptive to web-based interventions as compared to traditional approaches. Furthermore, personalized interventions are likely to be more effective than generalized health and diet information if they are tailored to a student’s level of interest to make lifestyle changes. Research is needed to explore the efficacy of applying digital technologies to tailored weight loss/weight gain prevention programs among our society’s youngest adults.
Muscle function after exercise-induced muscle damage: Considerations for athletic performance in children and adults

Exercise-induced muscle damage is a welldocumented phenomenon which usually results after a bout of unaccustomed exercise or a series of movements involving eccentric muscle actions. In this form of muscle action, the muscle lengthens whilst it simultaneously attempts to contract. Important features of eccentric muscle action, which largely account for the extent of damage experienced in this form of contraction, are the higher forces exerted in comparison to concentric/isometric contractions and the lower motor unit activation for a given force ratio when compared to concentric/isometric muscle contractions. Such a profile of eccentric exercise places considerable stress on fewer motor units and often results in an immediate and prolonged reduction in the forceand power-generating capacity of the muscle. The consequences of damage on dynamic, multi-joint, sport-specific movements are most pertinent to athletic performance, but this aspect of muscle function has been studied less often. In addition, prior eccentric exercise has been observed to increase the physiological demand of endurance exercise and increase the thermal strain during exercise in the heat. The damage resulting from eccentric exercise also compromises the awareness of joint position and subjective estimation of muscle force output. The extent and severity of these effects appears to be moderated by gender, age, individual Roger ESTON ( ), Craig TWIST School of Sport, Health and Exercise Sciences University of Wales, Bangor George Building Bangor, Gwynedd LL57 2PX United Kingdom e-mail: r.g. eston@bangor.ac. uk Tel: (01248) 38 2824 Christopher BYRNE Centre for Human Performance, Defence Medical and Environmental Research Institute, DSO National Laboratories, Republic of Singapore Craig TWIST Department of Sport & Exercise Sciences, North East Wales Institute of Higher Education, Wrexham, UK differences in the elastic characteristics of muscle and prior eccentric and concentric exercise and training. This review takes account of some of these factors, summarizes the functional decrements in performance associated with exercise-induced muscle damage and relates these decrements to theoretical views regarding underlying mechanisms.
Glutamine-Supplemented Tube Feedings Versus Total Parenteral Nutrition in Children Receiving Intensive Chemotherapy

Although enteral nutrition is generally advocated in the care of children with cancer, those patients receiving intensive chemotherapy alone or in combination with bone marrow transplantation often require total parenteral nutrition (TPN). Two patients are presented illustrating some differences between enteral and parenteral feedings in children receiving intensive chemotherapy. Nasogastric glutamine-supplemented tube feedings were well tolerated both in the hospital and at home. The cost of care for the enterally supported child was less than one third of the TPN-supported child. Although TPN appears to be beneficial in some patients with cancer, it is expensive and is associated with several significant disadvantages. Among these are an increased incidence of both gram-positive and gram-negative infections and an increased incidence of gastrointestinal symptoms. Enteral nutrition is less costly than TPN and maintains the structural and functional integrity of the intestinal mucosa. The addition of certain substrates such as glutamine, arginine and omega-3 fatty acids may improve the body's immune response as well. We hypothesize that early glutamine supplemented tube feedings in children receiving intensive chemotherapy alone or in combination with bone marrow transplantation will result in improved nutrition with fewer infections and lower cost than TPN-supplemented patients. In addition, a shorter hospital stay and improved quality of life are anticipated.
Functional and diffusion MRI biomarkers of mild cognitive impairment

Memory dysfunction in mild cognitive impairment (MCI) is primarily associated with episodic memory deficits linked to deterioration of the medial temporal lobes (MTLs). Current suggested criteria for the diagnosis of MCI call for the discovery of novel biomarkers. Functional activation differences in MCI during memory-task performance are often evidenced in the MTLs, and frontal and parietal lobes, but it has been suggested that examination of working memory (WKM) differences may be more useful in detecting MCI. In the current study, MCI and control participants performed a complex WKM span (CWKMS) task while functional magnetic resonance imaging (fMRI) data was acquired. Results indicated hyper-activation of the superior temporal gyrus (STG), MTLs, and the insula during encoding and maintenance, and hyperactivation of the STG, MTLs, insula, and ventromedial frontal and anterior cingulated cortices during recall for the MCI participants. MTL differences are consistent with previous findings, but such localized differences in the STG are quite novel. Hyper- activation of the STG during WKM encoding and maintenance suggests that long-term phonological mechanisms associated with regions of the STG are necessary to maintain items in the focus attention. Increased recruitment of these mechanisms for the MCI patients suggests that may be attempting to compensate for poor encoding abilities that may partly resulted from MTL neurodegeneration. Therefore, hyper-activation of the STG during WKM encoding and maintenance, and/or recall is a possible novel biomarker
Accounting Information, Renegotiation, and Debt Contracts∗

We study the role of accounting measurement in the renegotiation of debt contracts. The use of accounting measurement in the control rights allocation rule has a trade-off. It improves the initial allocation of control rights but induces accounting manipulation. Renegotiation adds a new incentive for accounting manipulation and affects both aspects of the trade-off. A lower renegotiation cost reduces the benefit of accounting-based allocation of control rights and exacerbates accounting manipulation. With this interaction, we show that the ex-ante firm value is increasing in renegotiation cost if and only if the accounting quality is high and the manager’s bargaining power is large. The interaction also generates some new insights about the equilibrium use of accounting measurement in debt contracts, accounting manipulation, the frequency of renegotiation and the interest rate. JEL classification: M40, M41, G32
A Study of Photostability of PVC in Presence of Some Organic Compounds

Organic solar cells was refer to photo voltaic cells and it was a kind of green energy source of great potential application due to low production costs, mechanical flexibility devices. The aim of our work was to focus on the evolution of the polymeric solar with comparing studies for the period 2007-2015.
The Determination of Acute Oral L-Carnitine Ingestion on Physiological and Biochemical Parameters Related with Lipids in Endurance Exercise

BACKGROUND AND OBJECTIVE: Despite an abundance of literature, describing the basic mechanisms of action of L-carnitine, there remains some uncertainty regarding the effects of supplementation on fatty metabolism in healthy subjects. The purpose of this investigation was to determine the effects of acute oral L-carnitine supplementation on fat metabolism responses and endurance performance. METHODS: In this semi experimental study, thirty-four healthy male subjects consist of two experimental (n=17) and control (n=17) group performed a submaximal exercise protocol on cycle ergometer (PWC 170 ) in two separate stages. In first stage, exercise protocol performed without L-carnitine or placebo (Lactose) supplementation. In second stage, exercise protocol performed with acute L-carnitine or placebo supplementation (3g, 90 minute before exercise). Blood samples were taken immediately after exercise protocol for analyze and calculation plasma concentrations of free fatty acid, triglyceride and the other fat metabolism indexes (LDL, HDL, TC, Lipase and then two groups were compared. FINDINGS: The finding showed that there were no significantly differences between pre and posttest in plasma concentrations of free fatty acid (0.69±0.24 versus 0.72±0.14 mg/dL and triglyceride (158±46 versus 155±47 mg/dL. The rest and exercise heart rate and VO2max was 36±11 versus 35±9 mL/min. CONCLUSION: The mitochondrial transport of free fatty acid does not increase by L-carnitine supplementation. Collectively, L-carnitine supplementation would be unlikely to be associated with change in fat-carbohydrate metabolism in healthy people and it's not influence in improving of endurance performance.
A Unique Case of Non-cardiac Chest Pain Caused by Mepolizumab: Case Report and Review of the Literature

Non-cardiac chest pain is defined as chest pain that is identical to ischemic chest pain but with a reasonable workup excluding cardiac causes. Evaluation with upper endoscopy, esophageal manometry, and pH monitoring is typically performed to rule out gastrointestinal etiologies. Studies have shown that around half of patients who experience non-cardiac chest pain have abnormal pH testing. In this case report, we describe the first case of non-cardiac chest pain caused by mepolizumab, a medication used in the treatment of asthma.
A Meta-Analysis of Pregnancy Outcomes with Levothyroxine Treatment in Euthyroid Women with Thyroid Autoimmunity.

CONTEXT Thyroid autoimmunity (TAI), the most common cause of (sub)clinical hypothyroidism, is associated with adverse pregnancy outcomes. The benefits of levothyroxine (LT4) intervention in women with TAI remain controversial. OBJECTIVE To determine the effect of LT4 on pregnancy outcomes in euthyroid women with TAI. CONCLUSION No definitive evidence showed improvement of pregnancy outcomes with LT4 supplementation in euthyroid women with TAI. However, therapeutic strategies, especially dosages and initial times of intervention, may be of great importance. Additional large RCTs are needed in the future.
Sonic hedgehog expression in zebrafish forebrain identifies the teleostean pallidal signaling center and shows preglomerular complex and posterior tubercular dopamine cells to arise from shh cells

Ventralization, a major patterning process in the developing vertebrate neural tube (central nervous system, CNS), depends on Sonic hedgehog (SHH) as a main signaling morphogen. We studied the CNS of late larval and young adult zebrafish in a transgenic shh‐GFP line revealing increased neuroanatomical detail due to the progressed differentiation state compared to earlier stages. Some major findings emerge from the present study. (a) shh –GFP is still expressed along the adult zebrafish CNS neuraxis in most locations seen in larvae. (b) We newly identify a ventroposterior shh pallidal domain representing the basal telencephalic signaling center important for basal ganglia development known in other vertebrates (i.e., the anterior entopeduncular area—basal medial ganglionic eminence of mammals). (c) We further show late‐emerging shh‐GFP positive radial glia cells in the medial zone of the dorsal telencephalon (i.e., the teleostan pallial amygdala). (d) Immunostains for tyrosine hydroxylase demonstrate that there is selective colocalization in adult dopamine cells with shh‐GFP in the posterior tuberculum, including in projection cells to striatum, which represents a striking parallel to amniote mesodiencephalic dopamine cell origin from shh expressing floor plate cells. (e) There is no colocalization of shh and islet1 as shown by respective shh‐GFP and islet1‐GFP lines. (f) The only radially far migrated shh‐GFP cells are located in the preglomerular area. (g) There are no adult cerebellar and tectal shh‐GFP cells confirming their exclusive role during early development as previously reported by our laboratory.