Miracle-dz/UniFAR-FTUs huggingface dataset:
Reimplantation of cultivated human bone cells from the posterior maxilla for sinus floor augmentation. Histological results from a randomized controlled clinical trial.

OBJECTIVES The aim of the present randomized clinical study was to evaluate histologically whether the addition of cultivated, autogenous bone cells to a composite graft of deproteinized bovine bone mineral (DBBM) and autogenous bone (AB) for sinus floor augmentation (SFA) enhance bone formation compared with what achieved after SFA with DBBM + AB alone. MATERIAL AND METHODS Twenty patients with remaining posterior maxillary alveolar crest height of less than 3 mm received SFA after randomization either with an DBBM and AB composite in a 1 : 1 ratio or with DBBM + AB supplemented with autogenous bone cells, which were cultivated from a bone biopsy harvested earlier from the tuberosity area. Four months after SFA, two cylindrical biopsies were taken from the augmented sinuses concomitantly with the implant site preparation by means of a trephine bur. An additional biopsy was taken from the tuberosity area. Bone density at the augmented sinus and the tuberosity area and the height of augmentation were estimated on non-decalcified histological sections prepared from the biopsies. A relative bone density index (RBD) was also calculated by dividing bone density at the augmented sinus with bone density at the tuberosity area. RESULTS All patients but one could receive two implants after SFA; in one patient, only one implant could be placed. All implants were osseointegrated and could be loaded. Median bone density in the sinus was 30% and 25% in the cell seeded and no-cells added DBBM + AB groups, respectively. Bone augmentation height averaged 6.0 and 5.4 mm and RBD averaged 0.48 and 0.73 in the cell seeded and no-cells added DBBM + AB groups, respectively. None of the differences between groups was statistically significant. CONCLUSIONS Cultivated autogenous bone cell seeded to a DBBM + AB composite did not significantly improve bone formation (density and height) after SFA, compared with what was achieved with DBBM + AB alone. Both approaches resulted into enough bone to support implant placement and osseointegration.
Alcohol, Anxiety, and Depressive Disorders

Alcoholics frequently experience episodes of intense depression and/or severe anxiety. Depressed or anxious alcohol-dependent people often believe that they drink to relieve symptoms of sadness or nervousness. However, research does not unanimously support the prior existence of severe depressive or anxiety disorders as a usual cause of alcoholism. A review of recent literature (from family studies, prospective investigations, and studies of children of alcoholics) on the complex interaction between alcohol dependence and independent anxiety/depressive disorders reveals that if an association between alcoholism and anxiety/depressive disorders does exist, it likely operates in a relatively small subgroup of alcoholics at the same time. Psychological symptoms may carry a worse prognosis for alcohol-related problems, and these symptoms must be addressed early in alcoholism treatment.
Acculturation, Acculturative Stressors, and Family Relationships Among Latina/o Immigrants

Objectives: Family relationships, widely recognized as core to Latino cultures, are known to vary for Latina/o immigrants based on time in the United States. Less is known about (a) how acculturation explains differences in family relationships by time in the US, and (b) whether acculturative stressors influence different aspects of immigrants’ family relationships. Drawing on an expanded acculturation framework, we explore whether and how attitudinal familism, family contact, and family conflict among immigrant Latina/os vary based on acculturation and acculturative stressors. Method: Using nationally representative data on foreign-born Latina/os (National Latino and Asian American Study; N = 1,618), ordered logistic and OLS regression analyses examined whether differences in family relationships by time in the US are explained by acculturation factors, and whether acculturative stressors are associated with family relationships when controlling for other important sociodemographic factors. Results: Accounting for acculturation reduces the effect of time in the US on attitudinal familism and family conflict to nonsignificance. Spanish language proficiency and ethnic identity are associated with higher attitudinal familism, while English proficiency is associated with increased family conflict. Additionally, acculturative stressors (involuntary context of exit, hostile context of reception, limited origin country ties) are associated with lower attitudinal familism and higher conflict. Conclusions: Results highlight the importance of (a) examining the ways that migration influences multiple aspects of family relationships, (b) adopting a more comprehensive acculturation framework. Particularly novel are our findings on how acculturative stressors are associated with different family outcomes.
Fatigue in psychiatric HIV patients: a pilot study of psychological correlates.

BACKGROUND Even though viral management of HIV infection is now more effective, clinical observations suggest that fatigue remains a problem for a substantial proportion of patients. OBJECTIVE The authors delineated prevalence and severity of fatigue in HIV patients with psychiatric comorbidities and examined psychological correlates of fatigue. METHOD The authors comprehensively assessed fatigue in 38 consecutive HIV patients referred for psychiatric treatment with the Identity-Consequence Fatigue Scale. RESULTS About 80% of patients reported at least moderate feelings of fatigue, and about 25% judged that fatigue was severely affecting their daily functioning. Depression, anxiety, and perceived stress explained between 20% and 75% of the variance in fatigue ratings. DISCUSSION The results suggest that fatigue in the era of effective antiretroviral treatment is prevalent, relevant, and related to psychological morbidities. Recognition and treatment of these comorbidities may be important in reducing this fatigue.
ORIGINAL ARTICLE: Bcl‐2 and Bax Expressions in Pre‐Term, Term and Post‐Term Placentas

Problem Placental apoptosis‐associated protein imbalance might contribute to the pathogenesis of pre‐ and post‐term birth. Therefore, we evaluated the expression and distribution of pro‐apoptotic (Bax) and anti‐apoptotic (Bcl‐2) molecules in term, pre‐term and post‐term placentas.
Ketogenic diet poses a significant effect on imbalanced gut microbiota in infants with refractory epilepsy

AIM To investigate whether patients with refractory epilepsy and healthy infants differ in gut microbiota (GM), and how ketogenic diet (KD) alters GM. METHODS A total of 14 epileptic and 30 healthy infants were recruited and seizure frequencies were recorded. Stool samples were collected for 16S rDNA sequencing using the Illumina Miseq platform. The composition of GM in each sample was analyzed with MOTHUR, and inter-group comparison was conducted by R software. RESULTS After being on KD treatment for a week, 64% of epileptic infants showed an obvious improvement, with a 50% decrease in seizure frequency. GM structure in epileptic infants (P1 group) differed dramatically from that in healthy infants (Health group). Proteobacteria, which had accumulated significantly in the P1 group, decreased dramatically after KD treatment (P2 group). Cronobacter predominated in the P1 group and remained at a low level both in the Health and P2 groups. Bacteroides increased significantly in the P2 group, in which Prevotella and Bifidobacterium also grew in numbers and kept increasing. CONCLUSION GM pattern in healthy infants differed dramatically from that of the epileptic group. KD could significantly modify symptoms of epilepsy and reshape the GM of epileptic infants.
Chapter 2 Classification Using Fuzzy Rough Granular Neural Networks 2

In Chap.1, a comprehensive description of granular computing, rough fuzzy computing and different classification, clustering and feature selection methods is provided. This chapter deals with pattern classification in the framework of granular neural networks. As mentioned in Chap.1, the problem of classification is basically one of partitioning the feature space into regions, one region for each category of input. A finite and usually a small number of samples, called a training set, provides partial information for optimal design of classifying system, in terms of the values of the parameters, for different tasks of pattern recognition. Different types of classifiers are briefly described in Sect. 1.5. 3 of Chap.1. As mentioned there, integration of various components of soft computing like fuzzy sets, rough sets, fuzzy rough sets and artificial neural networks provides a new way in which the fuzzy neural networks and rough fuzzy neural networks for classification are developed in pattern recognition framework. These methods can handle uncertainties arising from overlapping classes. In doing so, fuzzy sets are associated with multilayer perceptron (MLP) to design neuro-fuzzy inference model [6]. A fuzzy MLP for classification is designed in [15]. Here fuzzy sets are used to define input vectors of MLP in terms of 3-dimensional (3D) linguistic terms corresponding to low, medium and high. In this chapterwe first describe the salient features of neuro-fuzzy inferencemodel and fuzzyMLP.The networks subsequently developed based on thesemodels are then discussed. These are followed by a rough fuzzy neural network, by integrating rough set theory with fuzzy MLP, along with its characteristic features. Incorporation of rough reducts, as obtained from the training data, as initial network parameters is seen to enhance the classification performance while reducing training time significantly. Finally we describe in detail some of the recent granular neural networks, namely, FRGNN1 [4] and FRGNN2 [5] with experimental results.
Neuromuscular Alterations in Middle-Distance Runners i Prior Band-Resisted Squat Jumps Improved Running Time , Rating of Perceived Exertion , and Neuromuscular Performance in Middle-Distance Runners

ii ACKNOWLEDGEMENTS . iii TABLE OF CONTENTS . iv LIST OF TABLES . vi LIST OF FIGURES . vii LIST OF ABBREVIATIONS . viii Chapter 1: Review of Literature . 1 1.
Chapter 2 Earth-Abundant Cu 2 ZnSn ( S , Se ) 4 ( CZTSSe ) Solar Cells

Current benchmark thin film solar cell (TFSC) technologies based on polycrystalline CuInxGa1−xS(Se)2 (CIGS) and CdTe absorber materials have reached record efficiencies of 20.8 and 19.6 % for laboratory-scale devices and have already reached the commercial production stage [1]. However, these thin film photovoltaic (PV) technologies suffer from serious issues of toxicity, skyrocketing material cost, and/or low abundance of raw materials, which are predicted to severely limit the production, mass deployment, and economic sustainability of these solar cells [2–9]. Indium (In), gallium (Ga), and tellurium (Te) supply have been categorized as “critical” by the US Department of Energy (DOE) and the European Commission (EC) [10, 11]. Particularly, In supply for CIGS production could be stringent as more than 80 % of In produced worldwide is consumed by the flat panel display (FPD) industry and with ever-increasing demand of such displays, sustainability and economic viability of CIGS PV technology could be in great danger in upcoming years [12]. Also, due to the environmental health concerns, use of toxic cadmium (Cd) hinders the mass production and deployment of CdTe solar cells [13]. Thus, an intense research effort has been triggered to develop alternative thin film solar absorber materials comprising of earth-abundant, low-cost, and non-toxic elements which can yield high-efficiency devices, be economically
INFLUENCE OF THE RESEARCHED AREA AND PART OF THE CARCASS ON SOME QUALITY INDICATORS OF SHEEP DRY-CURED HAM

“Stelja” is an autochthonous dried meat product of sheep meat, and more rarely of goat meat, traditionally produced for centuries across Bosnia and Herzegovina. It is a very popular and respected product, especially for the Bosnians. The aim of the research was to determine whether the production technology of different localities and anatomical part of the carcass from which the sample was taken (Musculus longissimus dorsi and thigh with the leg), affected the overall quality of the sheep dry-cured ham samples. Besides that, one of the aims of the research was to collect certain qualitative parameters of the product in order to protect the product both at the national and the European Union level. Tests were carried out in five different areas in Bosnia and Herzegovina. In total, 30 female animals of domestic sheep (“Pramenka”) of different strains were used for the whole study. After selecting the animals, slaughter of animals and production of dry-cured sheep ham was carried out. For qualitative tests, sampling was performed after drying and cooling dry-cured sheep ham. Samples were taken from the three rib excerpt of the long back muscle and the thigh with the leg. In this research examined the slaughterhouse indicators and tests of sensory, chemical and microbiological quality of the finished product. The results of chemical and sensory quality testing showed that there were significant differences (P < 0.05) linked to the influence of both the researched area and anatomical part of the carcass from which the sample was taken. By analysing the presence of heavy metals in the samples of long back muscle, it was found that the samples had been according to the EU legislation in force. Quantitative differences of the sensory properties were dependant on the researched area and the carcass part (P < 0.05). On the basis of the sheep slaughter values, it can be concluded that the tested parameters were dependent on the researched area (P < 0.05). Sensory evaluation of the dry-cured sheep ham “Stelja” confirmed high level of acceptability and quality of the product.
Erythema multiforme due to methotrexate reproduced with patch test

A 5-year-old female patient, with plantar juvenil dermatitis and family and personal history of atopic dermatitis, presented with bilateral and symmetrical diffuse erythema, vesicles, bullae and exulcerations on the dorsum of her feet and toes as well as on the plantar surfaces, with severe itching (Figs 1 and 2). The lesions evolved for 1 year and aggravated whenever she wore shoes, especially in summer. The severity of the clinical picture kept her away from school causing a significant impact in her psychosocial development. Patch tests with standard series of Portuguese Contact Dermatitis Group (GPEDC) and shoe series (Chemotechnique) resulted in the reactions summarized in Table 1. We advised the parents to use chromium-free tanned leather footwear over 2 pair of cotton socks. We also stressed the need of having 2 pairs of shoes to alternate day-byday, allowing them to dry. Although not sensitized, the use of rubber shoes was not recommended. Occlusion and moist environment would worsen juvenile plantar dermatitis and could promote new sensitizations. The use of topics containing Balsam of Peru was forbidden. With these strategies and topical corticosteroids, the lesions improved gradually and disappeared in 3 weeks with no recurrence in a 6-month follow-up.
Nexus between Internet Penetration and Financial Inclusion in Nigeria

This study examined the relationship between internet penetration and financial inclusion in Nigeria. Frequencies, percentages and tables were used to present data while obtained data was tested for empirical evidence using Two-staged regression analysis in E-views 10. Findings revealed that internet penetration has significant impact on financial inclusion in Nigeria within the period under review. It was recommended that there is need for the adoption of highly internet based transactional policies that will ensure that the financially excluded is reached easily
A comparison of application frequency of physical therapy modalities in patients with chronic mechanical low back pain.

Objectives This study aims to evaluate the effects of physical therapy modalities five days a week versus twice a week with a three-day interval on pain, depression, and functional disability in patients with chronic mechanical low back pain. Patients and methods Between June 2018 and November 2018, a total of 60 patients (39 females, 21 males; mean age 41.0±6.8 years; range, 25 to 55 years) with chronic mechanical low back pain were included. The patients were divided into two groups: Group 1 (n=30) received physical therapy five days a week for a total of 15 sessions, while Group 2 (n=30) received physical therapy twice a week with a three-day interval for a total of six sessions. Per protocol, all patients were applied hot pack for 20 min, followed by conventional transcutaneous electrical nerve stimulation (TENS) for 20 min and therapeutic ultrasound (US) for 10 min in each session. All patients were given exercise training and were instructed to do twice a day up to four weeks after the completion of physical therapy sessions. The severity of low back pain was evaluated using the visual analog scale (VAS), the severity of depression using the Beck Depression Inventory (BDI), and functional disability using the Oswestry Disability Index (ODI). All patients were evaluated before and after physical therapy and at four weeks. The results were compared between the groups. Results There was no statistically significant difference in the age, gender, body mass index, occupation, VAS, BDI, and ODI scores at the time of randomization (p>0.05). Intra-group analysis showed a significant improvement in all parameters after physical therapy compared to pre-treatment values and at four weeks compared to the post-treatment values (p<0.001). The differences of changes were used for the inter- group analysis which revealed a difference of change in favor of improvement was significantly higher in Group 2 than Group 1 (p<0.001). There was no significant difference between the post-treatment values and values at four weeks (p>0.05). Conclusion Our study results suggest that both physical therapy modalities applied five days week and twice a week are effective in pain, depression, and functional disability. However, physical therapy protocol applied twice a week yields more improvement, indicating that it is more advantageous with less cost and lost workdays.
A NEW APPROACH TO THE MEASUREMENT AND CLASSIFICATION OF FORMS OF SUPERSENSITIVITY OF AUTONOMIC EFFECTOR RESPONSES

1 It is proposed that sensitizations of autonomic effectors to agonists by drugs or procedures be considered in two main categories: those involving changes in the effective concentration of agonist at receptors (type I) and those involving changes in the responding tissue beyond the initial combination of agonist and receptors (type II). Type I sensitizations are appropriately described by determining the dose‐ratio (horizontal shift of the dose‐response curve) and type II sensitizations by assessing the change in the magnitude of the response. 2 The inadequacy of the dose‐ratio in assessing sensitizations related to an altered physiology of the responding tissue is illustrated by means of hypothetical examples with particular reference to the slopes of dose‐response curves and altered maximal responses. 3 An evaluation of the enhancement of responses of rabbit aortic strips to agonists by reserpine indicates that it is a type II sensitization. The shifts of dose‐response curves to noradrenaline, isoprenaline, normetanephrine and 5‐hydroxytryptamine after reserpine‐treatment, were described both by the dose‐ratio and by the increment in the magnitude of the response at various contraction amplitudes. The dose‐ratio varied unpredictably for each agonist depending on the response level selected for comparison and also varied between agonists. However, the mm increment in response magnitude after reserpine approximated a constant value. Responses to potassium which by horizontal procedures were assessed among the least increased, were found to be enhanced the most when considered as a type II sensitization. 4 It is concluded that both type I and type II procedures should be applied when dealing with an unidentified sensitization and that the data be critically assessed. The appropriate use of these procedures can aid in identifying and clarifying sensitizations, as well as in elucidating the sequence of steps between receptor activation and response in an effector.
CASCODE LIGHT-normally-on JFET stand alone performance in a normally-off Cascode circuit

SiC power devices are known to show best performance in terms of switching losses. Since the SiC Schottky-barrier diodes became commercially available in 2001, transistors are in the focus of development. Because of its electrical behaviour and reliability, the SiC normally-on JFET seems to be one of the best candidates for future low loss unipolar switch application [1]. For safety reasons at startup and in failure mode, circuit designers aiming at normally-off switch characteristic. Therefore, normally-on high voltage SiC JFETs were combined with standard low-voltage MOSFETs forming a normally-off Cascode circuit. This paper analyzes the Cascode function in inverter application and explains drawbacks of the classical solution. To get rid of the Cascode problems, a so called Cascode Light approach was realized combining best JFET stand alone performance with the safety of a standard Cascode.
THE EFFECTS OF HIGH-TEMPERATURE HEAT-TREATMENT ON PHYSICAL PROPERTIES AND SURFACE ROUGHNESS OF ROWAN ( SORBUS AUCUPARIA L . )

Heat treatment of wood has attracted a lot of attention both in Europe and recently in North America as an environmentally-friendly wood-protection method. Th e untreated wood is hydrophilic (high affi nity for water). During the heat treatment, wood becomes more and more hydrophobic (low affi nity for water) with increasing heat treatment temperature. As a result, it becomes dimensionally more stable compared to untreated wood. Th e high temperature thermal treatment of wood is an environment-friendly method for wood preservation. Th is technique has attracted considerable attention in recent years. Th is study investigated the infl uence of heat treatment on the physical and surface roughness of Rowan (Sorbus aucuparia L.) wood to understand its role in wood processing. Samples obtained from Kastamonu Forest Enterprises, Turkey, were subjected to heat treatment at varying temperatures and durations. Th e physical properties of heat-treated and control samples were tested, and ovendry density, air-dry density, and swelling properties were determined. A stylus method was employed to evaluate the surface characteristics of the samples. Roughness measurements, using the stylus method, were made in the direction perpendicular to the fi ber. Four main roughness parameters, mean arithmetic deviation of profi le (Ra), mean peak-to-valley height (Rz), root mean square roughness (Rq), and maximum roughness (Ry) obtained from the surface of wood were used to evaluate the eff ect of heat treatment on the surface characteristics of the specimens. Signifi cant diff erence was determined (p = 0.05) between physical properties and surface roughness parameters (Ra, Rz, Ry, Rq) for three temperatures and three durations of heat treatment. Th e results showed that the values of density, swelling and surface roughness decreased with increasing temperature treatment and treatment times. Th e results obtained in this study provide important information for future research and utilization of thermally modifi ed wood.