Miracle-dz/UniFAR-FTUs huggingface dataset:
Syddansk Universitet Delta tocotrienol in recurrent ovarian cancer . A phase II trial

Delta tocotrienol has anti-neoplastic activity as demonstrated in several in-vitro and in-vivo investigations. The effect relies on inhibition of different pathways. It also has antiangiogenic activity, and an additive effect to bevacizumab may be expected. The present study was a phase II trial of bevacizumab combined with tocotrienol in chemotherapy refractory ovarian cancer. The study also included analysis of circulating tumor specific HOXA9 methylated DNA (HOXA9 meth-ctDNA) during treatment. The study included 23 patients. The rate of disease stabilization was 70% with very low toxicity. The median PFS was 6.9 months and the median OS 10.9 months, which is rather high compared to the current literature. A division of the patients according to level of HOXA9 meth-ctDNA already after the first cycle of chemotherapy resulted in two groups of patients with different prognoses. Patients with an increasing level of HOXA9 methctDNA had a median PFS and OS of 1.4 and 4.3 months, respectively, compared to 7.8 and 12 months in the group with stable or decreasing levels. The combination of bevacizumab and tocotrienol is potent in chemotherapy refractory ovarian cancer. The level of HOXA9 meth-ctDNA after one cycle of chemotherapy holds important prognostic information.
de travail Documents de travail « A strategic model of complex networks formation » Auteurs

This paper introduces a spatialized variation of the Connections model of Jackson and Wolinski (1996). Agents benefit from their direct and indirect connections in a communication network. They are arranged on a circle and bear costs for maintaining direct connections which are linearly increasing with geographic distance. In a dynamic setting, this model is shown to generate networks that exhibit the small world properties shared by many real social and economic networks.
Temporal and Spatial Change in Diameter Growth of Boreal Scots Pine , Norway Spruce , and Birch under Recent-Generation ( CMIP 5 ) Global Climate Model Projections for the 21 st Century

We investigated how climate change affects the diameter growth of boreal Scots pine (Pinus sylvestris L.), Norway spruce (Picea abies (L.) H. Karst. ), and silver birch (Betula pendula Roth) at varying temporal and spatial scales. We generated data with a gap-type ecosystem model for selected locations and sites throughout Finland. In simulations, we used the current climate and recent-generation (CMIP5) global climate model projections under three representative concentration pathways (RCPs) forcing scenarios for the period 2010–2099. Based on this data, we developed diameter growth response functions to identify the growth responses of forests under mild (RCP2.6), moderate (RCP4.5), and severe (RCP8.5) climate change at varying temporal and spatial scales. Climate change may increase growth primarily in the north, with a clearly larger effect on birch and Scots pine than Norway spruce. In the south, the growth of Norway spruce may decrease largely under moderate and severe climate change, in contrast to that of birch. The growth of Scots pine may also decrease slightly under severe climate change. The degree of differences between tree species and regions may increase along with the severity of climate change. Appropriate site-specific use of tree species may sustain forest productivity under climate change. Growth response functions, like we developed, provide novel means to take account of climate change in empirical growth and yield models, which as such include no climate change for forest calculations.
Utilization of some Chicken Edible Internal Organs and Wheat Germ in Production of Sausage

Relatively huge amounts of wheat germ are produced annually as a by-product of wheat milling industry in Egypt. Wheat germ had high amounts of protein, ash, fat, carbohydrates and bioactive compounds. The aim of the work was to study the possibility of using chicken’s gizzard and liver in production of sausage and effect of substitution of gizzards and liver meat by wheat germ at levels 5, 10, 15 and 20% on proximate composition, physical properties, sensory characteristics and microbiological criteria and after storage at 4oC for 15 day. A sensory evaluation showed that gizzards and liver sausage was very acceptable from the standpoint of color, taste, odor, juiciness, tenderness and overall acceptability. Storage at 4oC for 15 day of studied sausage caused slightly decreased in moisture, crude protein and fat but increase in total carbohydrates. The results of microbiological analysis showed that refrigerated storage of gizzards and liver sausage samples lead to increase in the total viable bacterial count and psychrophilic count whereas all samples was free from coliform, Salmonella and Shigella. It is recommended to use chicken gizzards and liver in sausage processing after good and quick cleaning with a percentage exceeds 20% of wheat germ.
Empirical U-Quantiles of dependent data = Empirische U-Quantile abhängiger Daten

The aim of this thesis is the investigation of the asymptotic behaviour of empirical U -quantiles under dependence. U -quantiles are a generalization of order statistcs and are applicated in robust statistics. Examples are the Hodges-Lehmann estimator of location or the Qn estimator of scale. Furthermore, we want to study generalized linear statistics, which are linear combinations of U -quantiles. An important tool for the analysis of the asymptotic distribution of quantiles is the Bahadur representation, which gives a relation to the empirical distribution function. U -quantiles can be approximated by the empirical U -distribution function in this way. For this reason, we will develop some new results for U -statistics under di erent mixing assumptions. We will give pointwise and functional central limit theorems, laws of the iterated logarithm and strong invariance principles for U -quantiles. Ziel dieser Arbeit ist es, das asymptotische Verhalten von empirischen U -Quantilen unter Abhängigkeit zu analysieren. U -Quantile sind eine Verallgemeinerung von Ordnungsstatistiken und haben Anwendung in der robusten Statistik, so z. B. der Hodges-Lehmann-Schätzer für die Lage einer Verteilung oder der Qn Skalenschätzer. Weiterhin wollen wir auch verallgemeinerte lineare Statistiken untersuchen, also Linearkombinationen von U -Quantilen. Ein wichtiges Hilfsmittel für die Analyse der asymptotischen Verteilung von Quantilen ist die Bahadur-Darstellung, mit der ein Zusammenhang zur empirischen Verteilungsfunktion hergestellt wird. U -Quantile lassen sich auf diese Weise durch die empirische U -Verteilungsfunktion approximieren. Aus diesem Grund werden wir auch einige neue Resultate für U -Statistiken unter verschiedenen Mischungsbedingungen entwickeln. Wir werden sowohl punktweise also auch funktionale Versionen des zentralen Grenzwertsatzes, des Gesetzes des iterierten Logarithmus und des starken Invarianzprinzips für U -Quantile beweisen.
O A ] 1 0 M ay 2 01 7 CLASSIFICATION OF UNIFORM ROE ALGEBRAS OF LOCALLY FINITE GROUPS

We study the uniform Roe algebras associated to locally finite groups. We show that for two countable locally finite groups Γ and Λ, the associated uniform Roe algebras C∗ u (Γ) and C∗ u (Λ) are ∗-isomorphic if and only if their K0 groups are isomorphic as ordered abelian groups with units. This can be seen as a non-separable non-simple analogue of the Glimm-Elliott classification of UHF algebras. To the best of our knowledge, this is the first classification result for a class of non-separable unital C∗-algebras. Along the way we also obtain a rigidity result: two countable locally finite groups are bijectively coarsely equivalent if and only if the associated uniform Roe algebras are ∗-isomorphic. Finally, we give a summary of C∗-algebraic characterizations for (not necessarily countable) locally finite discrete groups in terms of their uniform Roe algebras. In particular, we show that a discrete group Γ is locally finite if and only if the associated uniform Roe algebra l∞(Γ)⋊r Γ is locally finite-dimensional.
ePubWU Institutional Repository

The number of newly developed Multi-Criteria Decision Making (MCDM) methods grew considerably in the last decades. Although their theoretical foundations are solid, there is still a lack of acceptance and application in the practical field. The objective of this research is the development of a conceptual model of factors that influence MCDM acceptance that serves as a starting point for further research. For this purpose, a broad diversified literature survey was conducted in the discipline of technology adoption and related topics (like human computer interaction) with special focus on MCDM acceptance. The constructs collected within the literature survey were classified based on a qualitative approach which yielded a conceptual model structuring the identified factors according to individual, social, technology-related, task-related and facilitating aspects.
Board Independence , Environmental Disclosure , and Firm Value

This study aims to examine the effect of board independence and environmental disclosure on firm value. Board Independence is measured using the proportion of Independent Commissioner, and environmental disclosure is measured using Indonesian Environmental Reporting (IER) index, and firm value is measured by Tobin's Q. The sample of this research includes 134 companies over a period of 2009-2013, which were collected by using purposive sampling method. This study employes mutiple linear regression method to analize the observations. The result shows that both the board independence and environmental disclosure significantly effect firm value. These results confirm the argument that independency and transparency as a pilars of corporate governance increase firm value.
Liquefaction of oxyfuel flue gases – Experimental results and modeling of heat transfer coefficients for pure CO 2

In this paper heat transfer coefficients for film condensation of carbon dioxide under elevated pressures are presented. The examined pressure ranges from 16-30 bars with a constant mass flow of 12 kg/h CO2. Therefore, a pilot plant for cryogenic liquefaction of CO2 has been built. In the installed tube in tube condenser cooling media temperatures from -25 °C to -45 °C were used. During the experiment heat transfer coefficients between 4500 and 13000 W/(mK) were determined. Afterwards the experimental data were compared to common correlations for film condensation. The aim was to prove whether the influence of the elevated pressure can be predicted. Finally, all correlations could predict the heat transfer under elevated pressures in a suitable manner, concerning the uncertainties in modeling and determination of heat transfer coefficients. Nevertheless not all correlations could predict the influence of elevated pressures equally well. © 2013 The Authors. Published by Elsevier Ltd. Selection and peer-review under responsibility of SINTEF Energi AS.
Interactive comment on “ Synthetic ozone deposition and stomatal uptake at flux tower sites ” by Jason A . Ducker

This manuscript describes the development and application of a method to predict the deposition flux of ozone to vegetation. Specifically, the stomatal deposition is quantified. The method is based on flux measurements of latent heat (evapotranspiration) and other micrometeorological parameters at over 100 FLUXNET sites in North America and Europe. Measured data are used wherever possible. The analysis is based on the present-day knowledge as available in the literature, and on sound understanding of all processes involved. A rigorous uncertainty analysis is performed. Data of the synthetic flux estimate are compared to measured data of 3 sites. Uncertainties of the synthetic fluxes on the one hand and of the measured fluxes on the other hand were in the same range. Overall, the ozone deposition flux and stomatal flux can be
FEDERAL RESERVE BANK OF SAN FRANCISCO WORKING PAPER SERIES Bond Flows and Liquidity : Do Foreigners Matter ?

In their search for yield in the current low interest rate environment, many investors have turned to sovereign debt in emerging economies, which has raised concerns about risks to financial stability from these capital flows. To assess this risk, we study the effects of changes in the foreign-held share of Mexican sovereign bonds on their liquidity premiums. We find that recent increases in foreign holdings of these securities have played a significant role in driving up their liquidity premiums. Provided the higher compensation for bearing liquidity risk is commensurate with the chance of a major foreign-led sell-off in the Mexican government bond market, this development may not pose a material risk to its financial stability. JEL Classification: E43, E44, F36, G12
TECHNOLOGY-BASED INTERVENTIONS: A META-ANALYSIS TECHNOLOGY-BASED INTERVENTIONS FOR ANXIETY DISORDERS IN YOUTH: A META-ANALYSIS By

Anxiety disorders are one of the most common disorders among children and adolescents (Beesdo, Knappe, & Pine, 2009), but often go untreated due to barriers such as time and cost (Salloum, Johnco, Lewin, McBride, & Storch 2016). Technology based Cognitive Behavioral Therapy treatments have been shown to be as effective at treating anxiety disorders as traditional interventions and can help to alleviate some of those barriers (Podina, Mogoase, David, Szentagotai, & Dobrean, 2016; Hedman et al., 2011; Ebert et al., 2015). Although there have been a few meta-analysis studies published regarding this topic, there is a need to explore technology-based interventions further. Past meta-analysis studies have not looked at the relationship between number of sessions and length of sessions to total efficacy, and past research has not looked at parental involvement as a potential moderator. The present metaanalysis sets out to investigate the overall efficacy of technology-based interventions, compare the efficacy of different technology-based interventions, investigate the relationship between number of sessions and length of sessions to total effect size, and look at parental involvement as a potential moderator. Overall, the results show that technology-based interventions are effective at decreasing anxiety symptoms (g = 0.71). Due to uneven group sizes, researchers were unable to compare the efficacy of the different technology groups. Pearson correlations found that there was not a significant interaction between number of sessions and length of sessions to total effect size (p = .594 and .058 respectively). Finally, results show that parental involvement is a moderator for total effect size, Z*diff = -1.07, p = . 020. The results of this study seem to suggest that technology-based interventions are a good option for treatment, but limitations to this study do apply and further investigation into technology-based interventions should still be done. TECHNOLOGY-BASED INTERVENTIONS: A META-ANALYSIS Table of
INFLUENCE OF THE LUNAR CYCLE ON THE FREQUENCY OF MATERNITY HOSPITAL ADMISSIONS : A RETROSPECTIVE STUDY

Objective: to analyze whether the frequency of maternity hospitals admissions is influenced by the lunar cycle. Method: an analytical, documentary, and retrospective study with a quantitative approach was carried out in a maternity hospital in the South of Brazil from July 2013 to July 2014. The sample was made up of 845 medical records of pregnant women. A descriptive data analysis was carried out with the use of the Fisher’s exact test and chi-square test. Results: approximately 84% (n=709) of the pregnant women were not admitted to the maternity hospital setting of the present study during the days of lunar change and no significant difference in the number of admissions in each lunar phase was found, determining p=0.1116. Conclusion: it was evidenced that lunar phase changes were not determining factors for the increase in the demand of obstetric care and hospital admission in the institution setting of the present study.
PREDICTORS OF CUSTOMER ACCEPTANCE AND RESISTANCE OF SMART TECHNOLOGIES IN THE RETAIL SECTOR

The rapid advancements in Internet technology have led to the development of numerous innovative smart technologies. This research investigates the customer acceptance and resistance of smart technologies in the retail sector by integrating the technology acceptance model, system characteristics, technology readiness, and store reputation literature. Data was collected using a quantitative survey and analysed using symmetrical PLS path modelling and asymmetrical fuzzy set qualitative comparative analysis (fsQCA). Results show complex relationships among perceived technology readiness, perceived ease of use, perceived usefulness, superior functionality, perceived adaptiveness, and store reputation in determining customers’ attitude and behavioural intentions towards smart retail technologies. The findings also show that technology readiness does not directly affect customer attitude but indirectly through perceived innovation characteristics. The findings indicate that retail stores should focus on smart technologies that are simple, yet offer enhanced customer value by improving the shopping efficiency. Retail stores can engage in brand management strategies to improve customers’ acceptance of SRT.
The Issuer-Pay Rating Model and Rating Inflation : Evidence from Corporate Credit Ratings

HAN XIA: The Issuer-Pay Rating Model and Rating Inflation: Evidence from Corporate Credit Ratings. (Under the direction of Paolo Fulghieri.) I demonstrate that the issuer-pay rating model adopted by major credit rating agencies contributes to their incentives to issue inflated ratings. Employing a unique dataset, I compare credit ratings based on the issuer-pay rating model to those based on the investorpay model. I find that when the expected payoff is high, the issuer-pay based rating agencies assign a more favorable rating to the issuer. Additionally, I present evidence that neither regulators nor investors seem to adjust for this rating bias. These findings raise questions about the effectiveness of credit ratings as a gauge of issuers’ credit quality. They also indicate that regulators’ efforts to promote a more transparent rating process will increase information production in the credit rating industry and benefit investors who use ratings to guide their investment decisions.
The quality of reporting of diagnostic accuracy studies in pelvic floor ultrasound : A systematic review

The quality of reporting of diagnostic accuracy studies in pelvic floor ultrasound: A systematic review A.T. M. Grob MSc, L.R. van der Vaart, dr. M.I. J. Withagen, prof. dr. C.H. van der Vaart 1 Department of Reproductive Medicine and Gynecology, University Medical Center, Utrecht, Netherlands 2 MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, Enschede, Netherlands 3 Medical student, Amsterdam Medical Center, Amsterdam, Netherlands
The Vortex Filament Equation

In this proceedings article we shall survey a series of results on the stability of self-similar solutions of the vortex filament equation. This equation is a geometric flow for curves in R3 and it is used as a model for the evolution of a vortex filament in fluid mechanics. The main theorem give, under suitable assumptions, the existence and description of solutions generated by curves with a corner, for positive and negative times. Its companion theorem describes the evolution of perturbations of self-similar solutions up to a singularity formation in finite time, and beyond this time. We shall give a sketch of the proof. These results were obtained in collaboration with Luis Vega. In the first section we shall present the vortex filament equation. Then in the second section we shall give the topics we are interested in, and state our results. The sketch of the proofs will be given in the last section. The author is partially supported by the French ANR project SchEq ANR-12-JS-0005-01. MSC 2000: 76B47, 35Q35, 35Q55, 35B35, 35P25.
FIRST DRAFT – Work In Progress ! Family Ownership and Effects on Firm Performance in Asia

The current literature on firm ownership around the world shows that concentrated ownership with only one or a few controlling owners is fairly common, especially in many European and Asian countries. Commonly, the controlling ownership is held by an individual, or a group of individuals, usually with family ties. The effects on the governance of the firm, the relation between shareholders and management and furthermore the level of investment performance of the firm is all ultimately affecting the economic development around the world. This paper presents a study of the effects on several measures of firm performance for 1363 firms in seven Asien countries, from family ownership, dispersed ownership and firm owner independence. The results show that the different performance measures must be interpreted separately due to their nature. Furthermore, family firms seems to be valued lower than non family firms, while the investment performance of family firms is higher than for non family firms. These results are in line with previous studies and confirm that family controlled firms are deemed to have competent management for investments but are generally considered to be at higher risk for managerial discretion of minority shareholders. JEL classification: G30, G32, L25
Power Electronics , Machines and Drives ( PEMD 2018 ) Selecting appropriate fuzzy PID control structure for power electronic applications

A comprehensive library of Fuzzy Proportional-Integral-Derivative (PID) controllers for power electronic systems has recently presented in the literature. In this library, the authors derived a 27 Fuzzy PID structures and many hybrid Fuzzy PID controllers. This paper is an extended research for the aforementioned work. Here and as a study case, a switched mode power converter (SMPC) application is considered showing the procedure for selecting the applicable structure from the derived FPID library. Such systems require robust, and highly dynamic performance, control schemes to facilitate optimum and high efficiency performance, often under a wide and challenging range of operating conditions. Here, a fuzzy PD + I (FPD + I) structure is directly selected from the derived FPID library. Simulation analysis and experimental validation on a DSP (TMS-320F28335) controlled prototype synchronous DC-DC buck converter demonstrate the superior dynamic performance and voltage regulation of the selected FPID structure compared to the conventional CPID control scheme.