Miracle-dz/UniFAR-FTUs huggingface dataset:
Life satisfaction in people with spinal cord injury during the first five years after discharge from inpatient rehabilitation

Purpose: To describe the course of life satisfaction in persons with spinal cord injury (SCI) during the first 5 years after discharge from inpatient rehabilitation and to examine its determinants. Methods: Multi-centre prospective cohort study with four measurements, the first at discharge from inpatient rehabilitation, the last 5 years after discharge. Data of 162 persons with SCI were analyzed. Life satisfaction was measured as the sum score of ‘current life satisfaction’ and ‘current life satisfaction compared to life satisfaction before SCI’. Lesion characteristics, functional independence, secondary impairments, pain, social support and self-efficacy were analyzed as possible determinants of life satisfaction. Random coefficient analysis was used for the analyses. Results: No significant changes in life satisfaction were found between discharge and 2 years later, however there were significant increases from two to 5 years post discharge. High functional independence, low pain, high everyday social support and high self-efficacy were significant determinants of a positive course of life satisfaction after discharge. Conclusions: Increases in life satisfaction were found in persons with SCI in the long run. High functional status, low pain, good social skills and high self-efficacy were related to high life satisfaction. Implications for Rehabilitation A spinal cord injury (SCI) is a major life event leading to serious physical disability and secondary medical problems, which has important consequences for the life satisfaction of the persons involved. No changes in mean life satisfaction ratings were found between discharge and two years later, but slight increases in life satisfaction were reported from two to five years post-discharge in persons with SCI. High functional independence, low pain, high everyday social support, and high self-efficacy were significant determinants of a positive course of life satisfaction after discharge. A combined model of physical (functional independence and pain) and psychosocial factors (social support and self-efficacy) explained 66% of the variance in life satisfaction.
Migration and development of Gnathostoma procyonis Chandler, 1942, in mammalian hosts.

States. The morphology of the adult parasite was given by Chandler (1942). The larval development of this species in its first and second intermediate hosts was described in an earlier paper (Ash, 1962). The present study is concerned with the migration and development of G. procyonis in its natural host, the raccoon, as well as in various other experimental animals. In addition, the pathology associated with G. procyonis and the morphological and behavioral characters useful in distinguishing this species from a closely related one, G. spinigerum, are considered.
Systemic Preexposure Prophylaxis for HIV

Objective: To assess the real-world implications of oral tenofovir–emtricitabine (TDF-FTC) for HIV preexposure prophylaxis (PrEP) in clinical practice and highlight important considerations for its implementation. Data Sources: A search of PubMed (January 1996 through June 2013) was conducted using the terms HIV preexposure prophylaxis, HIV prevention, tenofovir, and emtricitabine. Abstracts from 2012-2013 HIV/AIDS conferences were also reviewed. Study Selection and Data Extraction: All pertinent original studies and review articles published in English were evaluated for inclusion. Reference citations from identified articles were examined for additional content. Data Synthesis: Although antiretroviral therapy has been highly successful in reducing AIDS outcomes and death in HIV-infected patients worldwide, transmission of HIV remains a major global health problem. The recent approval of oral TDF-FTC for HIV PrEP represents the latest biomedical intervention to help control this epidemic. Four published randomized studies evaluated the efficacy and safety of this combination to prevent HIV transmission in several at-risk populations, including men who have sex with men, serodiscordant couples, and heterosexuals residing in endemic regions. Overall, these studies demonstrated significant risk reductions in the incidence of new HIV infections with good short-term tolerability. Despite promising results from clinical studies, several limitations may hinder the utility of PrEP in clinical practice. Most importantly, PrEP was studied in the context of a comprehensive prevention program, including intensive counseling on adherence, high-risk behaviors, and traditional preventative measures. If PrEP is implemented without these adjunct measures, concerns about failure and increased resistance may eventually be realized. Conclusion: The greatest impact of PrEP, both clinically and financially, will likely arise from judicious application in select high-risk populations. If used appropriately, PrEP has the potential to augment reductions in the current incidence of new HIV infections, and pharmacists will have an important role in the careful selection and counseling of these targeted populations.
Specifying a framework for evaluating requirements Engineering Technology: Challenges and lessons learned

Evaluating requirements engineering technology is a challenging activity. It becomes even more difficult when having to evaluate the technology and thus to show its suitability in real settings, as access to industrial resources might be limited and the target domain might be complex or very sensitive. This paper reports on our experience in specifying an evaluation framework for requirements engineering technology. The technology aims to improve safety assurance and certification practices, and is being developed in the scope of a large-scale European research project. We focus on presenting the challenges encountered and the lessons learned while specifying the framework. These lessons summarise how we addressed, plan to address, or propose to address the challenges. This information can be useful for other researchers and practitioners that have to evaluate requirements engineering technology in general, and with industry and for safety assurance and certification in particular.
Anisotropic unilateral damage with initial orthotropy: A micromechanics-based approach

A micromechanics-based damage model able to describe the brittle response of initially anisotropic materials is presented. A special emphasis is put on the account of damage-induced anisotropy and unilateral behaviour related to microcracks closure effects. These both features clearly influence the inelastic deformation of microcracked materials and lead to even more complex consequences in the context of initial anisotropy. The aim of this work is then to derive a new strain-based formulation which allows representing the related interactions between all these phenomena. This is achieved through a recent two-dimensional energy-based micromechanical analysis that accounts for the fully anisotropic multilinear response of orthotropic materials weakened by arbitrarily oriented microcracks. On the other hand, the thermodynamics framework gives a standard procedure for the development of the damage evolution law. Throughout the paper, attention is put on the mathematical and thermodynamical consistency of the model to avoid difficulties usually associated to the simultaneous description of damage-induced anisotropy and unilateral effects. In addition to elastic constants, the model requires the identification of only two parameters related to damage evolution. The model has been implemented within the commercial finite-element code ABAQUS, and various numerical simulations are presented to illustrate its capabilities. Especially, evolution of the material symmetry and influence of opening-closure states of microcracks on the damage process are illustrated in the case of brittle matrix composites subjected to different loading cases (axis and off-axis loads, tension and compression, tension followed by compression).
Prognostic Significance of Paraglottic Space Invasion in T2N0 Glottic Carcinoma

Purpose:The purpose of this study was to evaluate the prognostic significance of paraglottic space invasion determined with pretreatment computed tomography (CT) for patients with T2N0 glottic carcinoma treated with radiotherapy (RT). Methods:Eighty patients with T2N0 glottic squamous cell carcinomas treated with definitive RT between 1983 and 2002 who had pretreatment CT information available regarding paraglottic space invasion were analyzed. Follow up ranged from 0.14 to 18 years (median, 7.1 years). No patient was lost to follow up. Results:Five-year outcomes were: local control, 78%; local control with larynx preservation, 80%; relapse-free survival, 71%; and cause-specific survival, 91%. Multivariate analyses of various parameters (including vocal cord mobility, paraglottic space invasion, supraglottic invasion, and subglottic extension) showed that only subglottic extension significantly influenced the probability of cure. Conclusion:Paraglottic space invasion is likely associated with increased tumor volume and, by itself, is not necessarily associated with poorer outcome after definitive RT.
Giant cavernous liver hemangiomas: effect of operative approach on outcome.

HYPOTHESIS The choice of operative technique for resection of giant cavernous hepatic hemangiomas has an effect on outcome. DESIGN Case series. SETTING Tertiary hepatobiliary surgery-liver transplantation service. PATIENTS AND INTERVENTIONS Fifty-two adult patients who underwent resection of symptomatic hepatic hemangiomas (38 [73%] in the right lobe; average diameter, 10.9 cm) by means of lobectomy or enucleation, with or without Pringle inflow occlusion. MAIN OUTCOME MEASURES Blood transfusion, morbidity, mortality, and length of hospitalization. RESULTS Patient age and sex and the size of hemangiomas were similar for patients who underwent lobectomy and enucleation. Right-lobe lesions were more often treated by enucleation, and inflow occlusion was used more frequently; transfusion requirements and length of hospitalization were similar for both techniques. Complications were more frequent after lobectomy. There were no deaths. In the latter years of the series, enucleation was used in 22 (63%) and inflow occlusion in 24 (69%) of 35 patients. CONCLUSIONS Outcome is related to the operative approach used for resection of giant cavernous liver hemangiomas. Although lobectomy and enucleation are curative, enucleation offers greater preservation of normal hepatic parenchyma and fewer complications and is the preferred technique for suitable lesions.
Identification of Immunodominant Antigens by Probing a Whole Chlamydia trachomatis Open Reading Frame Proteome Microarray Using Sera from Immunized Mice

ABSTRACT Chlamydia trachomatis infections can lead to severe chronic complications, including trachoma, ectopic pregnancy, and infertility. The only effective approach to disease control is vaccination. The goal of this work was to identify new potential vaccine candidates through a proteomics approach. We constructed a protein chip array (Antigen Discovery, Inc.) by expressing the open reading frames (ORFs) from C. trachomatis mouse pneumonitis (MoPn) genomic and plasmid DNA and tested it with serum samples from MoPn-immunized mice. Two groups of BALB/c female mice were immunized either intranasally or intravaginally with live elementary bodies (EB). Another two groups were immunized by a combination of the intramuscular and subcutaneous routes with UV-treated EB (UV-EB), using either CpG and Montanide as adjuvants to favor a Th1 response or alum to elicit a Th2 response. Serum samples collected at regular intervals postimmunization were tested in the proteome array. The microarray included the expression products of 909 proteins from a total of 921 ORFs of the Chlamydia MoPn genome and plasmid. A total of 185 immunodominant proteins elicited an early and sustained antibody response in the mice immunized with live EB, and of these, 71 were also recognized by the sera from mice immunized with UV-EB. The reactive antigens included some proteins that were previously described as immunogenic, such as the major outer membrane protein, OmpB, Hsp60, and IncA and proteins from the type III secretion system. In addition, we identified in mice several new immunogens, including 75 hypothetical proteins. In summary, we have identified a new group of immunodominant chlamydial proteins that can be tested for their ability to induce protection.
At the End of the Beginning: The Formalization of Property Rights in Emerging Markets

Acknowledgments I would like to thank the Chazen Institute for the opportunity to publish this paper, Robert Wegner for countless peer revisions and Shao Ping Yu for all of her work. I am also grateful to Professor Joseph Stiglitz, for whom this paper was initially written. He asked many questions and pointed me to the answers. The paper would not have been possible at all, however, without the generosity of Elena Panaritis, who shared parts of her original work on fixed property rights and market reform. What began as a conversation about her work at the World Bank and an innocuous question about if I could write a small economics of information paper based on her work evolved into a yearlong set of information exchanges, revisions, academic arguments, a new model and more revisions. When it was first described to me, I thought I would be able to summarize the concept in a few pages. Now I realize that what Panaritis did in Peru is an elegant solution to a profoundly complex problem—and after writing at least 20 versions of this paper, I have only just begun to understand how much work this must have been. It has been a privilege to have so many hours of conversation with and guidance from Panaritis. I am very grateful. J. MICHAEL GRAGLIA earned an MBA from Columbia Business School and an MA from the School of Advanced International Studies (SAIS) at the Johns Hopkins University. While pursuing graduate studies, he interned at the United Nations and worked as the interim country director for the International Catholic Migration Commission, the implementing partner for the UNHCR in Zimbabwe. Graglia spent two years with the U.S. Peace Corps in Namibia and founded Deep Roots, a 501(c)(3) corporation that funds the education of children in Namibia, Zambia and Guatemala. He holds a BA in mathematics from Gonzaga University in Spokane, Wash. ELENA PANARITIS is a specialist in the creation of markets in illiquid assets, property rights and public services. She is a visiting lecturer on international housing finance at the Wharton School, University of Pennsylvania, since 2001 and coteaches with Dr. Francis Fukuyama at the Johns Hopkins School of Advanced International Studies (SAIS). For the last 11 years, she served as economist, private/public sector specialist, at the World Bank, where she worked on privatization, property rights, market development, registries and judicial reform. A key example of …
Observation of Natural Lightning-Induced Voltage on Overhead Power Lines

This paper presents the analysis and observation results of the induced voltage waveforms caused by nearby natural lightning on overhead power lines in the Guangzhou field experiment site during the summer of 2008. Peak values of the induced voltage for 36 natural lightning return strokes ranged from 0.21 to 3.87 kV. And the double-peak oscillation phenomenon can be found in the waveforms. The interval time of adjacent return strokes ranged from 17.1 to 430.1 ms. The average 10%-10% peak value duration time of induced voltage waveform of the first return strokes is 244.6 μs, and that of the subsequent return strokes is 83.2 μs. The induced voltage waveforms on the live and neutral conductors are almost the same, while the induced voltage amplitude on the live conductor is slightly larger than that on the neutral conductor. The lightning location system data indicate that the induced voltage on the live and neutral conductor may be of either positive or negative polarity, depending on the lightning ground strike points. However, the amplitude of the induced voltage calculated by the Rusck model is smaller than those of the observation results, with the former being 60% of the latter.
Understanding Online Shopping Adoption in India: Unified Theory of Acceptance and Use of Technology 2 UTAUT2 With Perceived Risk Application

The purpose of this research is to analyze perceived risk and drivers of online shopping influencing behavioral intention in India. The study empirically validates website design, cash-on-delivery COD mode of payment, and different facets of perceived risk with the unified theory of acceptance and use of technology2 UTAUT2 of Venkatesh et al. [Venkatesh V, Thong JYL, Xu X 2012 Consumer acceptance and use of information technology: Extending the unified theory of acceptance and use of technology. MIS Quart. 361:157-178]. Findings of the study revealed that perceived risk had a negative relation with behavioral intention, whereas the drivers were positively associated with behavioral intention. Besides analyzing cash-on-delivery mode of payment as a construct, it also includes website design to enhance application of UTUAT2 in Indian and other similar developing countries' context. The study will help online retailers to focus in the right direction by eliminating threats and convert nonshoppers to online shoppers.
Predisposing Factors and Etiologic Diagnosis of Ulcerative Keratitis

Purpose: To determine the predisposing factors, demographic characteristics, and etiology of ulcerative keratitis in a referral center in Bangkok, Thailand. Methods: The medical records of admitted patients with positive-culture ulcerative keratitis were retrospectively reviewed for demographic data, predisposing factors, and microbial culture results. Predisposing factors were compared between bacterial and fungal keratitis. Results: From January 2001 to December 2004, there were 127 positive-culture ulcerative keratitis cases. The most frequent microbiological diagnosis was bacterial keratitis (76 eyes, 60%), followed by fungal (48 eyes, 38%) and Acanthamoeba keratitis (3 eyes, 2%). The most common organisms isolated were Pseudomonas spp. for bacteria and Fusarium spp. for fungus. Compared with bacterial keratitis, fungal keratitis was more likely to be associated with ocular trauma (odds ratio = 11.20; 95% confidence interval, 3.62-34.66) but less likely to be associated with contact lens wear (odds ratio = 0.02; 95% confidence interval, 0.01-0.08). Conclusions: In our study, Pseudomonas and Fusarium species are the most common causes of bacterial and fungal keratitis, respectively. Fungal keratitis was more likely than bacterial keratitis to be associated with ocular trauma, whereas fungal keratitis was less likely to be associated with contact lens wear.
Analisis Pengaruh Struktur Modal terhadap Kinerja Keuangan Perusahaan

At this time, business growth requires proper companys financial strategy, especially by managing the capitalstructure to meet funding need of business operations. This research describes the impact of capital structure onfinancial performance of finance company listed on the Indonesia Stock Exchange during the years 2009-2013. The dependent variable in this study is financial performance composed of return on assets ratio (ROA),return on equity ratio (ROE) and price-to-earnings ratio (PER). While the independent variable in the form ofcapital structure is the ratio of debt to total assets (DAR) and the ratio of debt to total equity (DER). The resultof panel data regression analysis showed that the capital structure has negative significant effect on financialperformance of ROA and ROE, but has positive significant effect on PER. Based on these results, the financecompanies should apply the precautionary principle in managing capital resources coming from debt financing,because the increased component of excessive debt in the capital structure of the company could lead to anincrease in the financial burden that affects the reduction in companys profit.
Size and value effects in equity hedge funds

ABSTRACT Contrary to the findings in mutual funds, both size and value effects appear in equity hedge funds. Small-cap/value funds outperform large-cap/growth funds. Both asset and share liquidity measures show that small-cap/value funds manage less liquid assets and are more likely to have lockup restrictions than large-cap/growth funds. Furthermore, small-cap/value funds earn more benefits from using lockups than large-cap/growth funds. In part, lockups are helpful for small-cap/value funds by mitigating a fire-sale risk during crisis periods.
Gauging Perceived Benefits from ‘Working from Home’ as a Job Benefit

This paper covers working from home as an employee benefit and looks to gauge the advantages and disadvantages for both employees and employers. The focus is on employees that work from home on behalf of an employer, not self-employed individuals. The article reviews secondary research on working from home. The primary research included in this paper was conducted via anonymous online surveys. Respondents were assured of anonymity, and ranged in their functional roles. The survey included ranking questions, as well as freeform short answer questions. This primary research is not positioned to be statistically representative of all employees and employers. This primary research does reflect a gauge on perspectives on working from home as a job benefit. Ultimately the results suggest that employees hold a very positive perspective on working from home, however, more can be done to help ensure perceptions on workplace promotional opportunities remain consistent for employees that work in an office or for home. Research also suggests that the greatest challenge for managers remains a lack of trust in results from employees they cannot physically see in the same location. Managers will find driving their employees’ performance through clearly defined metrics which will improve the trust.
Induction by Dopamine D 1 Receptor Agonist ABT-431 of Dyskinesia Similar to Levodopa in Patients With Parkinson Disease

Methods: We studied ABT-431, the prodrug of a fully selective D1 agonist, in 20 subjects with advanced Parkinson disease and a fluctuating response to levodopa complicated by dyskinesias. Eight patients were studied in a double-blind, randomized design (French centers); 12, in an open, randomized design (US centers). We assessed and compared the antiparkinsonian (Unified Parkinson’s Disease Rating Scale) and dyskinetic (response induced by an acute challenge of a suprathreshold dose of levodopa and by 4 different ascending doses (5, 10, 20, and 40 mg) of ABT-431 during the 6 hours after the challenge.
5 Gsample/s track-hold and 3 Gsample/s quasi-sample-hold ICs

Two fully-differential track-and-hold and quasi-sample-and-hold circuits are based on AlGaAs/GaAs-HEMTs with 6OGHz f/sub T/. The less complex of these circuits exhibits 7b linearity measured under worst case. The ICs work up to 5GSample/s at a differential input of 2V/sub p-p/ for the track-and-hold and 3GSample/s for the quasi-sample-and-hold. The THA can be directly merged with the source follower input stage of an A/D converter and is also suitable for Si bipolar technology.