Miracle-dz/UniFAR-FTUs huggingface dataset:
Home Appliance Identification for Nilm Systems Based on Deep Neural Networks

This paper presents the proposal for the identification of residential equipment in non-intrusive load monitoring systems. The system is based on a Convolutional Neural Network to classify residential equipment. As inputs to the system, transient power signal data obtained at the time an equipment is connected in a residence is used. The methodology was developed using data from a public database (REED) that presents data collected at a low frequency (1 Hz). The results obtained in the test database indicate that the proposed system is able to carry out the identification task, and presented satisfactory results when compared with the results already presented in the literature for the problem in question.
NEUROTROPHIN EXPRESSION IN SYMPATHETIC NEURONS: INFLUENCES OF EXOGENOUS NGF AND AFFERENT INPUT

NEUROTROPHIN EXPRESSION IN SYMPATHETIC NEURONS: INFLUENCES OF EXOGENOUS NGF AND AFFERENT INPUT by Elizabeth Ellen Jones The regulatory mechanisms that promote the survival of adult neurons remain unclear. Targetderived proteins called neurotrophins are known to play a role in the survival of sympathetic neurons, but their exact function is unknown. In the present study, expression of the neurotrophins nerve growth factor (NGF) and neurotrophin-3 (NT-3) in adult sympathetic ganglia and their targets was investigated. Using Western blot analysis, multiple precursor forms of both NGF and NT-3 were observed in neurons and blood vessel targets. In addition, using real time RT-PCR, transcripts for both NGF and NT-3 were detected in the ganglia, demonstrating the potential for neurotrophin synthesis in peripheral ganglia. The expression patterns of both NGF and NT-3 were found to be altered by both exogenous NGF and removal of pre-ganglionic input, suggesting the regulatory influences of both NGF and afferent input on neurotrophin expression and ultimately neuronal survival. Overall, this study advanced the understanding of neurotrophin regulation of neuronal survival NEUROTROPHIN EXPRESSION IN SYMPATHETIC NEURONS: INFLUENCES OF EXOGENOUS NGF AND AFFERENT INPUT
Title Visual prognosis of eyes with submacular hemorrhage associated with exudative age-related macular degeneration

Purpose To study the retinal structural changes associated with submacular hemorrhage due to exudative age-related macular degeneration (AMD) and their relationships with visual prognosis. Methods We retrospectively reviewed the medical records of 31 consecutive patients 5 (31 eyes) with visual impairment due to an acute submacular hemorrhage associated with typical AMD (10 eyes) or polypoidal choroidal vasculopathy (21 eyes). Results Optical coherence tomography (OCT) revealed that submacular hemorrhages exhibited intense hyperreflectivity beneath the neurosensory retina and often seemed to infiltrate the overlying neurosensory retina. In OCT sections, mild to moderate 10 amorphous hyperreflectivity and/or hyperreflective dots were observed within the neurosensory retina, resulting in the lack of the junction between the inner and outer segments of the photoreceptors (IS/OS). Of the 31 eyes, the foveal IS/OS line could be seen incompletely in 12 eyes and absent in 16 eyes. The initial integrity of the foveal photoreceptor layer was correlated with final visual acuity; the initial detection of the 15 IS/OS just beneath the fovea was correlated with good final visual acuity (r = 0.375, p = 0.038). Conclusion As a hallmark of integrity of the foveal photoreceptor layer, the initial detection of the IS/OS just beneath the fovea may predict good visual outcomes.
The Distance to NGC 4993: The Host Galaxy of the Gravitational-wave Event GW170817

The historic detection of gravitational waves from a binary neutron star merger (GW170817) and its electromagnetic counterpart led to the first accurate (sub-arcsecond) localization of a gravitational-wave event. The transient was found to be ∼10″ from the nucleus of the S0 galaxy NGC 4993. We report here the luminosity distance to this galaxy using two independent methods. (1) Based on our MUSE/VLT measurement of the heliocentric redshift (zhelio = 0.009783 ± 0.000023), we infer the systemic recession velocity of the NGC 4993 group of galaxies in the cosmic microwave background (CMB) frame to be vCMB = 3231 ± 53 km s−1. Using constrained cosmological simulations we estimate the line-of-sight peculiar velocity to be vpec = 307 ± 230 km s−1, resulting in a cosmic velocity of vcosmic = 2924 ± 236 km s−1 (zcosmic = 0.00980 ± 0.00079) and a distance of Dz = 40.4 ± 3.4 Mpc assuming a local Hubble constant of H0 = 73.24 ± 1.74 km s−1 Mpc−1. (2) Using Hubble Space Telescope measurements of the effective radius (15.″5 ± 1.″5) and contained intensity and MUSE/VLT measurements of the velocity dispersion, we place NGC 4993 on the Fundamental Plane (FP) of E and S0 galaxies. Comparing to a frame of 10 clusters containing 226 galaxies, this yields a distance estimate of DFP = 44.0 ± 7.5 Mpc. The combined redshift and FP distance is DNGC 4993 = 41.0 ± 3.1 Mpc. This “electromagnetic” distance estimate is consistent with the independent measurement of the distance to GW170817 as obtained from the gravitational-wave signal ( D GW = 43.8 − 6.9 + 2.9 Mpc) and confirms that GW170817 occurred in NGC 4993.
Health Risk Assessment Associated with Norovirus Incidence in Raw Wastewater in Jeddah, Saudi Arabia

Norovirus caused an epidemic gastroenteritis in humans. It can be transmitted by the fecal- oral and the aerosol route. Norovirus represent a most common cause of acute gastroenteritis which responsible about 42%-96% of nonbacterial gastroenteritis worldwide. Current study aims to detect a norovirus in Jeddah wastewater. A total one hundred of wastewater samples were collected from outlet of Al-Misk Lake east of Jeddah city over a period of fourteen months from January 2009 to February 2010. All samples were filtered and virus concentrated and screened for GII human. A molecular in- house detection was performed using nRT-PCR. The most conserved regions; N32, N33, N35 and N36 were used for primers design. Of 19 positive samples were signaled a band of 338bp. In conclusion, this study revealed that the norovirus was frequently present in Jeddah wastewater, which should be alert to do not use this water in land irrigation.
Prospects and promises in the study of resilience

Examinations of risk and psychopathology across the life course all too often portray the developmental process as somewhat deterministic, resulting in maladaptive and adverse outcomes. Studies ranging from genetic and biological predispositions to pathology, to assaults on development associated with inadequate caregiving, graphically convey the multiplicity of risks that eventuate in psychopathology. Thus, it is especially refreshing to explore the more optimistic component of the psychopathology-risk equation, namely, resilience. What individual, familial, or societal factors stem the trajectory from risk to psychopathology, thereby resulting in adaptive outcomes even in the presence of adversity? It is the answer to this query that the contributors to this Special Issue of Development and Psychopathology have directed their energies toward elucidating. This Special Issue may well be a "first" in its presentation of a group of articles detailing research strategies and empirical findings that are focused on the construct of "resilience. " Of course, a significant and il-
A convergent adaptive finite element method for electrical impedance tomography

In this work, we develop and analyse an adaptive finite element method for efficiently solving electrical impedance tomography—a severely ill-posed nonlinear inverse problem of recovering the conductivity from boundary voltage measurements. The reconstruction technique is based on Tikhonov regularization with a Sobolev smoothness penalty and discretizing the forward model using continuous piecewise linear finite elements. We derive an adaptive finite element algorithm with an a posteriori error estimator involving the concerned state and adjoint variables and the recovered conductivity. The convergence of the algorithm is established, in the sense that the sequence of discrete solutions contains a convergent subsequence to a solution of the optimality system for the continuous formulation. Numerical results are presented to verify the convergence and efficiency of the algorithm.
Accurate assessment of marine protected area success depends on metric and spatiotemporal scale of monitoring

Marine protected areas are being monitored to determine whether they increase abundance of fished populations, with responses often expected within a few years. Evaluations typically compare abundance inside versus outside or after versus before implementation, but the temporal and spatial scales over which these measures can reflect marine protected area success are untested. We modeled the response of fished populations for a range of marine protected area sizes, fishing intensities, larval dispersal distances, and adult movement ranges. Our results, which can inform experimental design and interpretation of monitoring, show that the spatial and temporal scale of population responses to marine protected areas will be determined by simple relationships between marine protected area size, larval and adult movement distances, and generation time, in addition to the effects of exploitation rate. The largest effects of marine pro- tected areas should be expected with 'outside' samples located at least 2 dispersal units from the edge, and after 2 generations have passed since establishment. In general, monitoring studies over time (after versus before) should provide better assessment of marine protected area success than monitoring over space (inside versus outside), but understanding of the limitations of each type of measurement is key. Because it may take many years for marine protected area effects to be fully realized, we strongly caution against judgment of marine protected area effectiveness at inappropriately short time frames.
Modeling the Metal Binding Site in Cupin Proteins

The name for cupin proteins is derived from the Latin term for small barrel, ‘Cupa’. Proteins that belong to the group of cupins adopt a barrel-like structure (Dunwell et al., 2001). According to the database of Structural Classification of Proteins (SCOP) (Murzin et al., 1995), the cupin proteins have been classified as members of ‘RmlC-like Cupins’ superfamily in the ‘Double Stranded Beta Helix’ (DSBH) fold, however, the nomenclature employed in the literature is somewhat ambiguous since JmjC transcription factors (Clissold & Ponting, 2001) display many features typical of the DSBH fold. These common characteristics for the DSBH fold include a pair of four-stranded antiparallel β-sheets constituting up to eight β strands which form the typical β-sandwich structure. The superfamily comprises of 20 families with members performing diverse functions ranging from enzymatic activities like dioxygenases, hydrolases, decarboxylases, epimerases and isomerases to non-enzymatic functions such as binding to auxin, seed storage, and nuclear transcription factors (Dunwell, 2001, 2004). The nature of substrates used in various enzymatic reactions differs in chemical types, size, and structure. The sequence identity is low among the members of this superfamily. The functional site of members of this superfamily is generally located at the center of a conserved barrel. The cupin domain usually consists of two sequence motifs, each corresponding to two -strands. A less conserved region separates these motifs. The conserved motifs, GX5HXHX3,4EX6G and GX5PXGX2HXX3N, together contain the residues involved in metal ion binding at the active site, that is known to play a functional role (Dunwell, 2001, 2004). It has been indicated that 10,346 cupin sequences (Finn et al., 2008) have been identified in 843 species that belong to eukaryotes, prokaryotes, archaebacteria and viruses. In some plant species like O. sativa, V. vinifera and A. thaliana over 100 cupin sequences have been identified. This indicates the extent to which the cupins have diverged and duplicated in proteomes of various species to perform a variety of functions. Various metal ions, bound at the active site, including Iron, Manganese, Nickel, Copper, Zinc and Cadmium are known to play a functional role in the enzymatic members of cupin superfamily (Table 1). The metal cofactor can influence the chemistry of the catalytic reaction. The metal cofactor typically plays an important role in the function of cupins via an interaction with the substrate. An approach involving structure-based clustering of uncharacterized proteins within a group of proteins of known function can provide clues about their possible functions. It thus appears likely that this method would be a valuable tool for the functional annotation of structural genomic target proteins that are similar in structure despite the lack of sequence similarity.
Molecular Mechanisms of Nephro-Protective Action of HE-86 Liquid Extract in Experimental Chronic Renal Failure

Li-qun He1, Dong Feixia2, Qiang Fu3 and Jun Li4 1Department of Nephrology, Shuguang Hospital Affiliated with Shanghai University of Traditional Chinese Medicine, Ministry of Education Key Laboratory of Liver and Kidney Disease Syndrome, E-Institutes of Shanghai Municipal Education Commission, Innovative Research Team in Universities of Shanghai Municipal Education Commission 2Department of Nephrology, Wenzhou TCM Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine, Wenzhou 3Heilongjiang University of Traditional Chinese Medicine, HeiLongJiang 4Zhuhai City NO 5 Hospital, GuangDong China
A quantitative analysis of objective feather color assessment: Measurements in the laboratory do not reflect true plumage color

ABSTRACT An important driver of the evolution of animal coloration is sexual selection operating on traits that are used to transmit information to rivals and potential mates, which has a major impact on fitness. Reflectance spectrometry has become a standard color-measuring tool, especially after the discovery of tetrachromacy in birds and their ability to detect UV light. Birds' plumage patterns may be invisible to humans, and therefore the establishment of reliable and quantitatively objective ways of assessing coloration not dependent on human vision is a technical need of primary importance. Plumage coloration measurements can be taken directly on live birds in the field, or in the laboratory (e.g., on collected feathers). However, which of these 2 approaches offers a more reliable, repeatable sampling method remains an unsolved question. Using a spectrophotometer, we measured melanin-based coloration in the plumage of Barn Swallows (Hirundo rustica). We assessed the repeatability of measures obtained with both traditional sampling methods to quantitatively determine their reliability. We used an ANOVA-based method for calculating the repeatability of measurements from 2 years separately, and a GLMM-based method to calculate overall adjusted repeatabilities for both years. The results of our study indicate a great disparity between color measurements obtained using both sampling methods and a low comparability across them. Assuming that measurements taken in the field reflect the real or “true” color of plumage, we may conclude that there is a lack of reliability of the laboratory method to reflect this true color in melanin-based plumages. Likewise, we recommend the use of the GLMM-based statistical method for repeatability calculations, as it allows the inclusion of random factors and the calculation of more realistic, adjusted repeatabilities. It also reduces the number of necessary tests, thereby increasing power, and it allows easy calculation of 95% CIs, a measure of the reliability and precision of effect-size calculations.
Chemical composition, fibre fraction and anti-nutritional substances of semi-arid browse forages of North-eastern Nigeria.

The nutritive value of leaves from eight different browse trees and shrubs were analyzed. They include Ficus polita, Ficus thonningii, Batryospermum paradoxum, Kigalia africana, Celtis integuifolis, Khaya senegalensis, Leptadenia lancifolia, and Ziziphus abyssinica. were collected from Gwoza, in Borno, State, Nigeria. The browse samples were analyzed for chemical composition, fibre fractions and anti-nutritive components of their leaves. Results showed no significant differences (P>0.05) in the DM content, which ranged from 95.2 to 97.0%. Leptadenia lancifolia, Ficus thonningi and Ficus polita recorded higher CP content which was significantly higher (P<0.05) than the CP content of the other browse plants analyzed. A range of 2.00 to 5.00% and 8.00 to 18.00% were recorded for EE and Ash values for the eight browse plants. The values reported for minerals showed that Ficus thonningii had the lowest value of Ca (0.75%) while Kigalia africana was low in P and Mg (10.00 and 0.15%). Their fibre contents showed a range of 37.3 to 51.2, 16.2 to 41.2, 4.9 to 12.7,45.84 to 50.92, 12.4 to 26.90g/100g for NDF, ADF, ADL, ADIash and Cellulose respectively. The values reported for anti nutritive factors range from 0.08 to 0.39 for TCT, 0.24 to 0.65 for phenolics, 2.02 to 2.55 for Saponin, 4.58 to 8.15 for Oxalate, 2.85 to 5.81 for phytate, 0.04 to 0.08 for HCN and 0.0005 to 0.002mg/g. The results showed that the browse species studied have good nutrients contents, low and safe levels of anti-nutritional factors, and may therefore form good feed resources for modern intensive ruminant animal production.
Cosmetic Surgery in Integral Homology $L$-Spaces

Let $K$ be a non-trivial knot in $S^3$, and let $r$ and $r'$ be two distinct rational numbers of same sign, allowing $r$ to be infinite; we prove that there is no orientation-preserving homeomorphism between the manifolds $S^3_r(K)$ and $S^3_{r'}(K)$. We further generalize this uniqueness result to knots in arbitrary integral homology L-spaces.
Efficient Side-Channel Protections of ARX Ciphers

The current state of the art of Boolean masking for the modular addition operation in software has a very high performance overhead. Firstly, the instruction count is very high compared to a normal addition operation. Secondly, until recently, the entropy consumed by such protections was also quite high. Our paper significantly improves both aspects, by applying the Threshold Implementation (TI) methodology with two shares and by reusing internal values as randomness source in such a way that the uniformity is always preserved. Our approach performs considerably faster compared to the previously known masked addition and subtraction algorithms by Coron et al. and Biryukov et al. improving the state of the art by 36%, if we only consider the number of ARM assembly instructions. Furthermore, similar to the masked adder from Biryukov et al. we reduce the amount of randomness and only require one bit additional entroy per addition, which is a good trade-off for the improved performance. We applied our improved masked adder to ChaCha20, for which we provide two new first-order protected implementations and achieve a 36% improvement over the best published result for ChaCha20 using an ARM Cortex-M4 microprocessor.
Tuning microcapsules surface morphology using blends of homo- and copolymers of PLGA and PLGA-PEG

We modulate precisely the surface morphology of polymer microcapsules containing perfluorooctyl bromide prepared by the solvent-evaporation technique by varying the percentage of PLGA-PEG copolymer in the formulation. As copolymer percentage increases, protrusions start to appear, become more numerous and finally fuse to yield sponge-like capsules. It has been postulated that the shell morphology arises from an interfacial tension instability. We show here that if an interfacial tension instability develops, it happens during the final step of polymer desolvation, when the interface is no longer fluid and interfacial tension changes cannot be monitored. The formation of protrusions occurs in order to accommodate all the PEG chains of the copolymer in a hydrophilic environment, since PEG and PLGA moieties are not miscible in the solid state.
Running head: EXPLORING ’THE AUTISMS’ AT A COGNITIVE LEVEL 1 In press in Autism Research: http://dx.doi.org/10.1002/aur.1630 Exploring ‘The Autisms’ at a Cognitive Level Running title: Exploring ‘The Autisms’ at a Cognitive Level

Cathriona Cantio, Cand.psych. (1, 2), Jens Richardt Møllegaard Jepsen, MSc. , PhD (3, 4), Gitte Falcher Madsen, MD, PhD (1), Niels Bilenberg, Professor, MD, PhD (1, 2), and Sarah White, PhD (5) (1) Child and Adolescent Psychiatric Department, Odense, Mental Health Services, Southern Denmark (2) Institute of Clinical Research, University of Southern Denmark (3) Centre for Neuropsychiatric Schizophrenia Research & Centre for Clinical Intervention and Neuropsychiatric Schizophrenia Research, Copenhagen University Hospital, Psychiatric Hospital Centre Glostrup, Denmark (4) Child and Adolescent Mental Health Centre, Mental Health Services Capital Region of Denmark, University of Copenhagen, Copenhagen, Denmark (5) Institute of Cognitive Neuroscience, University College London, London, UK Corresponding authors contact information Cathriona Cantio, Child and Adolescent Psychiatric Department, Odense, Sdr. Boulevard 29, 5000 Odense C, Denmark, Tel. : +45 24658731, Email: cathriona.cantio@rsyd.dk
Seeded growth of ZIF-8 on the surface of carbon nanotubes towards self-supporting gas separation membranes

We report the synthesis of the first continuous, inter-grown ZIF-8 membrane via the secondary growth method. ZIF-8 crystals were seeded and strongly anchored onto porous carbon nanotube bucky-paper supports and hydrothermally grown into a dense and continuous ZIF-8 network. The self-supporting hybrid metal organic framework membranes were characterized by scanning electron microscopy and shown to exhibit both a very homogeneous structure and a very smooth nanotube-metal organic framework interface. Gas adsorption (H2, CH4, CO2, N2) and permeation (He, CO2, N2 and Xe) tests were performed to evaluate the permeance of each gas and to predict the selectivity. The membranes were highly robust and sustained pressures as high as 500 kPa. Furthermore, the high selectivity of N2 over CO2 and Xe (33 and 163 respectively), shown by gas adsorption single gas permeation and mixed gas permeation clearly demonstrates the near defect-free nature of the membranes while the high hydrothermal stability of ZIF-8 makes these novel composites highly promising for water vapour saturated gas treatment.
The effect of hyperbaric oxygen therapy on the nervous system. Systematic review

Abstract Hyperbaric oxygen therapy (HBOT) is found among the interests of researchers who seek new methods of treatment of diseases of the nervous system. An increase of the partial pressure of oxygen in arterial blood within the appropriate range leads to numerous changes in the cells of the brain tissue. In this paper we analyse the results of selected articles describing HBOT used on pathologies of the nervous system such as stroke, autism, multiple sclerosis and cerebral palsy as well as in the course of research on animal models. The results are promising, although some studies struggled with numerous methodological problems and differences in the applied protocols, which resulted in conflicting results in individual interventions. In consequence, the need for further studies in randomised control trials and determination of the protocol by an international group of researchers dedicated to the use of HBOT was emphasised.