Miracle-dz/UniFAR-FTUs huggingface dataset:
L'analyse statistique de données appliquée à la surveillance multi-paramètres de versants instables

La difficulte a modeliser les mecanismes de rupture de mouvements de versants de grande ampleur limite fortement les capacites d'anticipation et d'alerte des dispositifs bases sur des criteres de detection deterministes simples. De par la multiplicite et la complexite des phenomenes en jeu ces dispositifs sont de plus propices aux situations de fausses alarmes ou d'occurrence de l'alea sans alarme. Pour s'affranchir de ces limites et faire face a la diversite et la complexite des situations d'aleas gravitaires rencontrees, des approches multi-parametres d'observation et de surveillance sont mises en oeuvre. L'evolution technologique des capteurs, des systemes d'alerte et de leurs protocoles d'acquisition permet aujourd'hui de collecter de maniere synchronisee de nombreux types de donnees de mesure : mecaniques, hydrologiques, geodesiques, meteorologiques, sismiques et micro-sismiques. L'enjeu des travaux actuels concerne l'exploitation automatique en routine des series chronologiques ainsi collectees et notamment : (1) l'analyse de l'evolution dans le temps des differentes variables, (2) la detection des singularites dans ces series, et (3) l'identification des interactions entre variables et des temps de transfert entre elles. In fine, ces travaux doivent permettre l'utilisation d'outils et methodes d'analyse statistique eprouves permettant d'etablir des lois probabilistes d'occurrence de l'alea redoute ou tout au moins une detection fiable des situations a risque. Dans cet article, il est propose d'illustrer ce propos a l'aide des chroniques de donnees multi-parametres collectees par l'INERIS sur le versant des Ruines de Sechilienne entre 2009 et 2013. Nous verrons que les processus d'analyse et d'exploitation ne sont pas immediats et qu'ils requierent des choix methodologiques, ainsi qu'un recul sur les donnees de mesure, les incertitudes associees, la resolution des techniques instrumentales deployees qui peuvent combiner des variables quantitatives, qualitatives, ponctuelles, volumetriques, les scenarios attendus, ou encore sur la prise en compte des informations redondantes ou contradictoires.
Effect of quinacrine on x-ray sensitivity and the repair of damaged DNA in Escherichia coli K-12.

Quinacrine (0.15 mM), when added to the postirradiation incubation medium of E. coli K-12 rec+ cells, markedly potentiated the killing induced by x-irradiation. Alkaline sucrose gradient studies showed that quinacrine was a potent inhibitor of the repair of DNA single-chain breaks in rec+ cells and that this inhibition was largely irreversible. The recA13 mutant (deficient in the slow repair of x-ray induced single-chain breaks in DNA) did not show radiation sensitization by quinacrine. The possible use of quinacrine as a radiation potentiator in humans is discussed.
Medical treatment of glaucoma: present and future

Introduction: In the last decades, the therapy of glaucoma has largely shifted from surgery to medical treatment thanks to the introduction of strongly effective formulations, that is, prostaglandin analogs and fixed combinations. This clinical scenario may dramatically change in the future thanks to the progresses in biochemistry, genetics and drug delivery technology. Areas covered: This review covers the strategies currently used to achieve effective medical reduction of intraocular pressure in clinical practice; treatments that are currently been experimented in humans and that may be clinically available in the next few years; treatments at preclinical stages; and future goals of glaucoma treatment (gene therapy, ocular implants and neuroprotection). Expert opinion: Apart from an adequate reduction of intraocular pressure, effective glaucoma treatments should guarantee other characteristics: good tolerability, low problems of adherence and, possibly, multiple ways of action. From this viewpoint, a crucial clinical role may be played by drugs remodeling the trabecular meshwork (i.e., ROCK inhibitors, metalloproteinases). Other strategies such as the use of ocular implants for drug delivery, neuroprotection or gene therapy could renew glaucoma management in the future, but need long-term rigorous verification of safety and efficacy.
Application of Ion Pairing Chromatography to the Analysis of Inorganic Analytes: Review

Abstract The separation challenges that keep arising from the constantly evolving practical applications encountered in ion‐pair chromatography (IPC) of inorganic analytes and inorganic elements containing compounds are reviewed. Emphasis is placed on species that are most important in the biochemical, biomedical areas or that are of concern in the environmental field. Examples will be given of the analysis and speciation of a wide variety of compounds in different matrixes. They assess the practical potential of this mature technique whose results are usually in agreement with those obtained via different analytical strategies. Eclectic hyphenations to achieve specific goals are also described.
Violências percebidas por homens adolescentes na interação afetivo-sexual em dez cidades brasileiras

O presente artigo apresenta as visoes de adolescentes do sexo masculino sobre o tema da violencia no namoro. A partir de entrevistas e grupos focais realizados em dez cidades brasileiras, entre 2007 e 2009, o texto toma como parâmetro a analise dos significados atribuidos pelos jovens as agressoes fisicas, psicologicas e sexuais no âmbito dos relacionamentos intimos. A metodologia do estudo se concentra nos depoimentos de 257 estudantes do sexo masculino, de idades entre 15 e 19 anos, de escolas publicas e privadas do pais. Os resultados do estudo mostram que os significados atribuidos ao fenomeno da violencia no namoro sao recortados por representacoes rigidas de papeis de genero, correspondendo as expectativas em relacao ao desempenho de homens e mulheres nas relacoes afetivo-sexuais.
Visual Impairment Registry of Patients from North Kolkata, Eastern India: A Hospital-based Study

Purpose: To study the demographic profile, severity and causes of visual impairment among registered patients in a tertiary care hospital in north Kolkata, eastern India, and to assess the magnitude of under-registration in that population. Methods: This is a retrospective analytical study. A review of all visually impaired patients registered at our tertiary care hospital during a ten-year period from January 2005 to December 2014, which is entitled for certification of people of north Kolkata, eastern India (with a population denominator of 1.1 million), was performed. Overall, 2472 eyes of 1236 patients were analyzed in terms of demographic characteristics, cause of visual impairment, and percentage of visual disability as per the guidelines established by the government of India. Results: Male patients (844, 68.28%; 95% confidence interval [CI], 65.69-70.87) registered more often than female patients (392; 31.72%, P = 0.0004). The registration rate for visual impairment was 11.24 per 100,000 per annum; this is not the true incidence rate, as both new patients and those visiting for renewal of certification were included in the study. Optic atrophy was the most common cause of visual impairment (384 eyes, 15.53%; 95% CI, 14.1-16.96). Conclusion: Commonest cause of visual impairment was optic atrophy followed by microphthalmos. Under-registration is a prevalent problem as the registration system is voluntary rather than mandatory, and female patients are more likely to be unregistered in this area.
[Relationship between HER-2/neu over-expression and androgen independent prostate cancer].

OBJECTIVE To detect HER-2/neu expression in prostate cancer tissues of both androgen dependent and independent groups and to evaluate the role of HER-2/neu in androgen independent prostate cancer. METHODS Immunohistochemical assay was used in the detection of HER-2/neu in the prostate cancer samples from 30 cases of androgen dependent cancer and 24 cases of androgen independent cancer. The correlation was analyzed between HER-2/neu over-expression and the tumor's clinical stage and Gleason score. RESULTS The rates of HER-2/neu over-expression were 10% and 33% in the androgen dependent group and the androgen independent group, significantly higher in the Gleason score >7 group and the clinical stage > T2 group than in the -7 group and the > T2 group (14.29% vs. 26.92%, 34.62% vs. 7.14%, P < 0.01). CONCLUSION The rate of HER-2/neu over-expression is high in androgen independent prostate cancer and is correlated with the tumor stage and Gleason score.
P300-BCI-based authentication system

An authentication system is the system that decides whether to accept or reject the claiming identity of a person. Biometric-based authentication utilizes the individuality in human physiological and behavioral characteristics to authorize a person. Brain-signal-based authentication system is relatively new comparing to other types of biometric data. In this paper, we proposed a novel method that applies P300-based Brain Computer Interface (BCI) technique to the authentication system. The main concept for P300-BCI-based authentication is that the Oddball paradigm eliciting P300 waves is secret to the attacker. The experiments were conducted to evaluate the proposed system. The trained P300 classification model has 0.831 accuracy rate. And the proposed authentication system has 0.325 False Rejection Rate (FRR), 0.00 False Acceptation Rate (FAR) for secret-unknown attack and 0.10 FAR for secret-known attack. This study has shown that P300 wave has good potential as a biometric for highly secured authentication system.
The Recent Increase in Atlantic Hurricane Activity: Causes and Implications

The years 1995 to 2000 experienced the highest level of North Atlantic hurricane activity in the reliable record. Compared with the generally low activity of the previous 24 years (1971 to 1994), the past 6 years have seen a doubling of overall activity for the whole basin, a 2.5-fold increase in major hurricanes (≥50 meters per second), and a fivefold increase in hurricanes affecting the Caribbean. The greater activity results from simultaneous increases in North Atlantic sea-surface temperatures and decreases in vertical wind shear. Because these changes exhibit a multidecadal time scale, the present high level of hurricane activity is likely to persist for an additional ∼10 to 40 years. The shift in climate calls for a reevaluation of preparedness and mitigation strategies.
Job rotation as a factor in reducing physical workload at a refuse collecting department.

The effect of job rotation on the physical workload was investigated for male employees working at a refuse collecting department. Before the introduction of job rotation, an employee worked as a street sweeper, as a refuse collector or as a driver. After the introduction of job rotation, every employee was allowed to alternate between two of the three possible jobs during the day, i.e. refuse collecting/street sweeping, refuse collecting/driving or street sweeping/driving. Two non-rotation groups (i.e. refuse collectors and street sweepers) and two rotation groups (i.e. refuse collectors/street sweepers and street sweepers/drivers) were mutually compared. The physical workload was determined by measuring the perceived load, energetic load and postural load during a full working day. Job rotation resulted in a significant decrease of the perceived load and energetic load and a slight decrease of the postural load. The results indicate that the total amount of work performed by means of job rotation resulted in an overall reduced physical workload of the employees of the refuse collecting department.
Brefeldin A and monensin inhibit the D quadrant organizer in the polychaete annelids Arctonoe vittata and Serpula columbiana

SUMMARY The D quadrant organizer is a developmental signaling center that is localized to the vegetal D quadrant in different spiral‐cleaving lophotrochozoan embryos and may be homologous to axial organizing regions in other metazoans. Patterning by this organizing center creates a secondary developmental axis and is required for the transition from spiral to bilateral cleavage and later establishment of the adult body plan. Organizer specification in equal‐cleaving embryos is thought to involve inductive interactions between opposing animal and vegetal blastomeres. To date, experimental demonstration of this interaction has been limited to molluscs and nemerteans. Here, we examine three families of equal‐cleaving polychaete annelids for evidence of animal–vegetal contact. We find that contact is present in the polynoid, Arctonoe vittata, but is absent in the serpulid, Serpula columbiana, and in the oweniid, Oweniia fusiformis. To interfere with cell signaling during the period predicted for organizer specification and patterning in A. vittata and S. columbiana, we use two general inhibitors of protein processing and secretion: Brefeldin A (BFA) and monensin. In A. vittata, we detail subsequent embryonic and larval adult development and show that treatment with either chemical results in radialization of the embryo and subsequent body plan. Radialized larvae differentiate many larval and adult structures despite the loss of bilateral symmetry but do so in either a radially symmetric or four‐fold radially symmetric fashion. Our results suggest that the D quadrant organizer is functionally conserved in equal‐cleaving polychaetes, but that details of its specification, induction, and patterning have diverged relative to other spiral‐cleaving phyla.
Perioperative management difficulties in parathyroidectomy for primary versus secondary and tertiary hyperparathyroidism.

BACKGROUND In patients with hyperparathyroidism, parathyroidectomy is the only curative therapy. Anaesthetic management differs function of etiology (primary vs. secondary or tertiary hyperparathyroidism) and surgical technique (minimally invasive or classic parathyroidectomy). OBJECTIVES To evaluate peri-operative management (focusing on hemodynamic changes, cardiac arrhythmias and patients' awakening quality) in parathyroidectomy for hyperparathyroidism of various etiologies, in a tertiary center. MATERIAL AND METHODS 292 patients who underwent surgery for hyperparathyroidism between 2000-2011 were retrospectively reviewed; 96 patients (19M/77F) presented with primary hyperparathyroidism (group A) and 196 (80M/116F) with secondary and tertiary hyperparathyroidism due to renal failure (group B). Biochemical parameters (serum calcium, phosphate, creatinine) were determined by automated standard laboratory methods. Serum intact PTH was measured by ELISA (iPTH - normal range: 15-65 pg/mL). OUTCOMES Median surgery duration was 30 minutes in group A (minimally invasive or classic parathyroidectomy) and 75 minutes in group B (total parathyroidectomy and re implantation of a small parathyroid fragment into the sternocleidomastoid muscle). During anaesthesia induction, arterial hypotension developed significantly more frequent in group B (57 out of 196 pts, 29.1%) than in group A (8 out of 96 pts, 8.34%), p<0.0001, especially in patients receiving Fentanyl-Propofol. During surgery and anaesthesia maintenance, bradycardia was significantly more frequent in group A (67 out of 96 pts, 69.8%) than in group B (26 out of 196 pts, 13.3%), p<0.0001, especially during searching of parathyroid glands. By contrary, ventricular premature beats were less frequent in group A (25 out of 96 pts, 25.25%) than in group B (84 out of 196 pts, 42.85%), p=0.003. There were no statistically significant differences between the studied group regarding frequency of arterial hypertension and hypotension, paroxysmal atrial fibrillation. CONCLUSIONS anaesthetic management in parathyroid surgery may be difficult because of cardiac arrhythmias (bradycardia in primary hyperparathyroidism and ventricular premature beats in secondary and tertiary hyperparathyroidism, respectively) and arterial hypotension during anaesthesia induction in patients with secondary and tertiary hyperparathyroidism.
esign for sustainability : From Evolution of d product design to design for system innovations and transitions

The paper explores the evolution of Design for Sustainability (DfS). Following a quasi-chronological pattern, our exploration provides an overview of the DfS field, categorising the design approaches developed in the past decades under four innovation levels: Product, Product-Service System, Spatio-Social and Socio-Technical System. As a result, we propose an evolutionary framework and map the reviewed DfS approaches onto this framework. The proposed framework synthesizes the evolution of the DfS field, showing how it has progressively expanded from a technical and product-centric focus towards large scale system level changes in which sustainability is understood as a sociotechnical challenge. The framework also shows how the various DfS approaches contribute to particular sustainability aspects and visualises linkages, overlaps and complementarities between these approaches. 2016 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
The Elephant Quantum Walk

We explore the impact of long-range memory on the properties of a family of quantum walks in a one-dimensional lattice and discrete time, which can be understood as the quantum version of the classical "Elephant Random Walk" non-Markovian process. This Elephant Quantum Walk is robustly superballistic with the standard deviation showing a constant exponent, $\sigma \propto t^{3/ 2}$ , whatever the quantum coin operator, on which the diffusion coefficient is dependent. On the one hand, this result indicates that contrarily to the classical case, the degree of superdiffusivity in quantum non- Markovian processes of this kind is mainly ruled by the extension of memory rather than other microscopic parameters that explicitly define the process. On the other hand, these parameters reflect on the diffusion coefficient.
Constraining the progenitor companion of the nearby Type Ia SN 2011fe with a nebular spectrum at +981 d

We present an optical nebular spectrum of the nearby Type Ia supernova 2011fe, obtained 981 d after explosion. SN 2011fe exhibits little evolution since the +593 d optical spectrum, but there are several curious aspects in this new extremely late-time regime. We suggest that the persistence of the ? 5800 A feature is due to Na? I D, and that a new emission feature at ? 7300 A may be [Ca? II]. Also, we discuss whether the new emission feature at ? 6400 A might be [Fe? I] or the high-velocity hydrogen predicted by Mazzali et al. The nebular feature at 5200 A exhibits a linear velocity evolution of ? 350 km? s? 1 per 100 d from at least +220 to +980 d, but the line's shape also changes in this time, suggesting that line blending contributes to the evolution. At ? 1000 d after explosion, flux from the SN has declined to a point where contribution from a luminous secondary could be detected. In this work, we make the first observational tests for a post-impact remnant star and constrain its temperature and luminosity to T ? 104? K? and? L? 104? L? Additionally, we do not see any evidence for narrow H ? emission in our spectrum. We conclude that observations continue to strongly exclude many single-degenerate scenarios for SN 2011fe.
Nuclear Detection of Cellular Retinoic Acid Binding Proteins I and II with New Antibodies

Apart from the retinoic acid nuclear receptor family, there are two low molecular weight (15 kD) cellular retinoic acid binding proteins, named CRABPI and II. Mouse monoclonal and rabbit polyclonal antibodies were raised against these proteins by using as antigens either synthetic peptides corresponding to amino acid sequences unique to CRABPI or CRABPII, or purified CRABP proteins expressed in E. coli. Antibodies specific for mouse and/or human CRABPI and CRABPII were obtained and characterized by immunocytochemistry and immunoblotting. They allowed the detection not only of CRABPI but also of CRABPII in both nuclear and cytosolic extracts from transfected COS-1 cells, mouse embryos, and various cell lines.
Quality of Service Based NOMA Group D2D Communications

Non-orthogonal multiple access (NOMA) provides superior spectral efficiency and is considered as a promising multiple access scheme for fifth generation (5G) wireless systems. The spectrum efficiency can be further enhanced by enabling device-to-device (D2D) communications. In this work, we propose quality of service (QoS) based NOMA (Q-NOMA) group D2D communications in which the D2D receivers (DRs) are ordered according to their QoS requirements. We discuss two possible implementations of proposed Q-NOMA group D2D communications based on the two power allocation coefficient policies. In order to capture the key aspects of D2D communications, which are device clustering and spatial separation, we model the locations of D2D transmitters (DTs) by Gauss–Poisson process (GPP). The DRs are then considered to be clustered around DTs. Multiple DTs can exist in proximity of each other. In order to characterize the performance, we derive the Laplace transform of the interference at the probe D2D receiver and obtain a closed-form expression of its outage probability using stochastic geometry tools. The performance of proposed Q-NOMA group D2D communications is then evaluated and benchmarked against conventional paired D2D communications.
Web-Based Medical Decision Support Systems for Three-Way Medical Decision Making With Game-Theoretic Rough Sets

The realization of the Web as a common platform, medium, and interface for supporting human activities has attracted many researchers to the study of Web-based support systems (WSS). An important branch of WSS is Web-based decision support systems that provide intelligent support for making effective decisions in different domains. We focus on decision making in Web-based medical decision support systems (WMDSS). Uncertainty is a critical factor that affects decision making and reasoning in the medical field. A three-way decision-making approach is an effective and better choice to lessen the effects of uncertainty. It provides the provision for delaying certain or definite decisions in situations that lack sufficient evidence or accurate information in reaching certain conclusions. Particularly, the option of deferment decisions is added in this approach that provides the flexibility to further examine and investigate the uncertain and doubtful cases. The game-theoretic rough set (GTRS) model is a recent development in rough sets that can be used to determine the three rough set regions in the probabilistic rough sets framework by determining a pair of thresholds. The three regions are used to obtain three-way decision rules in the form of acceptance, rejection, and deferment rules. In this paper, we extend the GTRS model to analyze uncertainty involved in medical decision making. Experimental results with a GTRS-based approach on different health care datasets suggest that the approach may improve the overall quality of decision making in the medical field, as well as other fields. It is hoped that the incorporation of a GTRS component in WMDSS will enrich and enhance its decision-making capabilities.