Miracle-dz/UniFAR-FTUs huggingface dataset:
Canalicular lacerations: repair with the Mini-Monoka® monocanalicular intubation stent.

BACKGROUND AND OBJECTIVE There are different techniques for reconstructing traumatic canalicular lacerations. The aim of this study is to report the surgical outcome with the Mini-Monoka monocanalicular stent (FCI Ophthalmics, Issy-Les Moulineaux, France). PATIENTS AND METHODS Patients with traumatic canalicular lacerations who underwent surgical reconstruction using the Mini-Monoka monocanalicular stent were included. The surgical outcome was based on subjective (epiphora) and objective (tear meniscus level, dye disappearance test, and lacrimal irrigation) findings after stent removal. RESULTS Nineteen patients (15 males, 4 females; mean age: 34 years) were included. The upper canaliculus was injured in 5 cases and the lower in 14 cases. Successful stenting was accomplished in all cases. Postoperative eyelid position was satisfactory in most patients. The mean period of stenting was 5 months and the mean postoperative follow-up period was 13 months. There were no cases of premature stent extrusion. Functional drainage after stent removal was normal in 94.7% of patients. Syringing showed full patency with no narrowing or reflux. CONCLUSION The Mini-Monoka monocanalicular stent is an effective tool in reconstructing traumatic canalicular lacerations. It is easy to use, carries a minimal risk of injury to the non-lacerated canaliculus, and results in high anatomical and functional success rates.
An accelerated nutrition transition in Iran

Abstract: Objective: To describe the emergence of the nutrition transition, and associated morbidity shifts, in the Islamic Republic of Iran. Design: Review and analysis of secondary data relating to the socio-political and nutritional context, demographic trends, food utilisation and consumption patterns, obesity, and diet-related morbidity. Results and conclusions: The nutrition transition in Iran is occurring rapidly, secondary to the rapid change in fertility and mortality patterns and to urbanisation. The transition is occurring against the backdrop of lack of sustained economicgrowth. There is considerable imbalance in food consumption with low nutrient density characterising diets at all income levels, over-consumption evident among more than a third of households, and food insecurity among 20% of the population. Obesity is an emerging problem, particularly in urban areas and for women, and both diabetes and other risk factors for heart disease are becoming significant problems.
A COMPARISON OF THE CHARACTERISTICS AND FATE OF BARROW'S GOLDENEYE AND BUFFLEHEAD NESTS IN NEST BOXES AND NATURAL CAVITIES

Abstract Barrow's Goldeneye (Bucephala islandica) and Bufflehead (B. albeola) are cavity-nesting waterfowl that have received considerable attention in studies using nest boxes, but little is known about their nesting ecology in natural cavities. We found larger clutch size, lower nesting success, and different major predators for Barrow's Goldeneyes nesting in boxes versus those nesting in natural cavities, but few differences for Bufflehead. These differences are attributed to the location and physical differences between Barrow's Goldeneye nest boxes and natural cavities that affect their conspicuousness to predators and conspecific nest-parasitizing females. Goldeneye boxes were concentrated in highly visible locations such as trees at water or forest edge. Natural cavity nests, on the other hand, were often abandoned Pileated Woodpecker (Dryocopus pileatus) cavities, which were more dispersed throughout the forest interior and concealed under dense canopy cover. Bufflehead natural cavity nests were typically closer to edges, which may account for their similarity with boxes. We conclude that in some respects, studies of Barrow's Goldeneye that use nest boxes may not be representative of birds nesting in natural cavities, whereas those of Bufflehead are more likely to be so. Comparación de la Ecología de Nidificación de Bucephala islandica y B. albeola en Nidos Artificiales y en Cavidades Naturales Resumen. Los especies de patos Bucephala islandica y B. albeola anidan en cavidades, por lo que con frecuencia han sido estudiadas usando nidos articificales, pero poco se conoce sobre su ecología de nidificación en cavidades naturales. Los individuos de B. islandica que anidan en nidos artificiales presentaron nidadas más grandes, menor éxito reproductivo y distintos depredadores que los individuos que anidan en cavidades naturales, pero detectamos pocas diferencias para B. albeola. Estas diferencias son atribuidas a la ubicación y a las diferencias físicas entre los nidos artificiales y las cavidades naturales de B. islandica que afectan su visibilidad para deprededores y hembras coespecíficas que parasitan los nidos. Los nidos artificiales de B. islandica estuvieron concentrados en lugares muy visibles como árboles al borde del bosque o a la orilla del agua. Por el contrario, las cavidades naturales frecuentemente fueron cavidades abandonadas de Dryocopus pileatus, las cuales se presentaron más dispersas por el interior del bosque y ocultas bajo un dosel denso. Las cavidades naturales de B. albeola se ubicaron típicamente más cerca del borde, lo que tal vez explica la semejanza con los nidos artificiales. Concluimos que en algunos casos, los estudios de B. islandica que utilizan nidos artificiales pueden no ser representativos de individuos que anidan en cavidades naturales, mientras que los estudios de B. albeola probablemente sí sean más representativos.
Accurate detection and estimation of radio signals using a 2D novel smart antenna array

This paper investigates the problem of Direction of Arrival (DOA) estimation using a 2D novel smart antenna array configuration that was recently presented by the authors in [1]. The proposed 2D novel configuration overcomes the drawback of uniform linear array (ULA) which cannot detect signals arriving at grazing incidence. The proposed 2D novel array configuration is able to resolve signals arriving from narrowband plane wave sources close to the array endfire. The proposed array configuration comprises of doubly crossed uniform linear arrays (ULAs) so that the size and computational load of the proposed array is identical to that of a 2N-element conventional ULA. MUltiple SIgnal Classification (MUSIC) is used as a tool of radio signal detection and estimation. A comparative study between ULA and the proposed 2D novel array is carried out in terms of effect of SNR (signal to noise ratio), number of scatterers, and number of snapshots.
Enzastaurin‐induced apoptosis in glioma cells is caspase‐dependent and inhibited by BCL‐XL

The novel protein kinase C‐β inhibitor enzastaurin (ENZA) induced apoptosis in LNT‐229 and T98G cells whereas A172 cells were resistant. Further, ENZA reduced proliferation in glioblastoma‐initiating cells T 269 and T 323 but did not induce apoptosis. ENZA‐induced apoptosis involved cleavage of caspases 3, 8, and 9 and led to mitochondrial cytochrome c release and was strongly suppressed by the broad spectrum caspase inhibitor zVAD‐fmk but only slightly by the expression of the viral caspase 1/8 inhibitor cytokine response modifier‐A. ENZA did not reduce the phosphorylation of protein kinase B (Akt), but of p70 S6 kinase and of its substrate S6 protein in T98G cells. Inhibition of the phosphatidylinositol 3 kinase signaling pathway did not restore sensitivity of A172 cells towards ENZA, and constitutively active Akt did not protect LNT‐229 and T98G cells from ENZA‐induced apoptosis. Dephosphorylation of glycogen synthase kinase 3β, a biomarker of ENZA action, and cell death induction by ENZA were separately regulated. Inhibition or activation of Akt only weakly modulated ENZA‐induced dephosphorylation of glycogen synthase kinase 3β. In ENZA‐resistant A172 cells, apoptosis ligand 2 (Apo2L.0)‐induced cleavage of caspases 3, 8, and 9 was increased by ENZA, resulting in synergistic activity of ENZA and Apo2L.0.
Prevention of Eating Disorders: A Review

Nearly 10% of young women experience clinical eating disorders (Lewinsohn et al., 2000), and an even greater amount of women experience subclinical eating disorders and risk factors association with eating disorders, such as body dissatisfaction. Eating disorders are associated with a number of negative physical and psychological consequences, increased risk of mortality, and are often severe and debilitating (Thompson & Stice 2001). Of the individuals who experience eating disorder symptoms and their negative consequences, less than 25% will receive treatment (Hudson et al., 2007; Johnson et al., 2002). For those that do receive treatment, treatment effects are limited with only 30% experiencing long-lasting symptom remission (Agras et al., 2000; Fairburn, 2002; Fairburn et al., 2009; Wilson et al., 2003), and approximately 20% drop out (Fairburn 2002). Treatment for eating disorders is also relatively expensive, and most insurance companies will not fund inpatient treatment for individuals with severe eating disorders (Shaw et al., 2009). Therefore, more efforts have been devoted to the development of effective programs for the prevention of eating disorders.
Risk factors for ineffective therapy in patients with bloodstream infection.

BACKGROUND Infections occurring among outpatients having recent contact with the health care system have been termed health care-associated infections. The objective of this study was to analyze the impact of health care-associated status on effectiveness of initial therapy in hospitalized patients with bloodstream infections. METHODS Prospective cohort study of adults with bloodstream infections at 3 North Carolina hospitals. Bloodstream infection was defined as health care-associated if it occurred within the first 48 hours after hospitalization and if patients had 1 of the following characteristics: had received home health services, outpatient intravenous therapy, or outpatient renal dialysis in the 30 days prior to hospital admission; had been hospitalized within 90 days prior to admission; or lived in a long-term care facility. RESULTS Of 466 bloodstream infections, 132 (28%) were community-acquired, 178 (38%) were health care-associated, and 156 (33%) were nosocomial. Multivariable logistic regression using community-acquired status as a reference identified health care-associated status (odds ratio, 3.1; 95% confidence interval, 1.6-6.1) and nosocomial status (odds ratio, 4.3; 95% confidence interval, 2.2-8.3) as independent predictors of ineffective initial antibiotic therapy. Among health care-associated characteristics, hospitalization in the 90 days prior to admission was independently associated with ineffective initial therapy (odds ratio, 2.4; 95% confidence interval, 1.4-4.2). CONCLUSIONS Among patients treated in the hospital for bloodstream infection, health care-associated status was an independent predictor of ineffective initial antibiotic therapy. Hospitalization within 90 days prior to hospital admission was the component of health care-associated status most strongly associated with ineffective initial therapy.
Anxiety Disorder : A Pilot Study Acceptance and Commitment Therapy for Generalized Social

can be found at: Behavior Modification Additional services and information for http://bmo.sagepub. com/cgi/alerts Email Alerts: http://bmo.sagepub. com/subscriptions Subscriptions: http://www.sagepub. com/journalsReprints.nav Reprints: http://www.sagepub. com/journalsPermissions.nav Permissions: http://bmo.sagepub. com/cgi/content/refs/31/5/543 SAGE Journals Online and HighWire Press platforms): (this article cites 54 articles hosted on the Citations
Spontaneous remission of parathyroid adenoma followed with ultrasonographic examinations

Parathyroid adenoma has been known to rarely undergo spontaneous remission due to intraparathyroidal hemorrhage or i n f a r ~ t i 0 n . l ~ ~ However, because of the small size of this organ, we have failed to diagnose this special condition without postoperative pathological analysis. Recently, the neck ultrasound examination has become a more beneficial method for the diagnosis had already been made because her serum parathyroid hormone (PTH) concentration was revealed to be as high as 1290 ng/dL (normal: 23 ng/dL to 56 ng/dL). Physical examination on admission showed the patient to be almost normal except for epigastric tenderness caused by accompanied pancreatitis.
Canine neoplasia – population‐based incidence of vascular tumours

We have identified thirteen breeds that are registered in the Norwegian Canine Cancer Register with more than five cases of newly diagnosed, primary vascular neoplasia in the period from 1990 to 1998. Incidence rates have been estimated for the boxer and the Bernese mountain dog because the population at risk is known as a result of the 1992/93‐census of the Bernese mountain dog, boxer and bichon frisé.
Inhibition of simian virus 40 T-antigen expression by cellular differentiation

Murine 3T3T stem cells transfected with pSV3neo DNA were employed to study the effects of somatic cell differentiation on simian virus 40 (SV40) T-antigen expression. This experimental approach was used because the 3T3T cell line is a well-characterized in vitro adipocyte differentiation system and the pSV3neo plasmid contains the early region of the SV40 genome and a selective marker, G418 resistance. Cell clones containing stably integrated pSV3neo which expressed T antigen were isolated in G418-containing medium. Most of these cell clones differentiated poorly. However, several clones retained the ability to efficiently differentiate into adipocytes, and with these cell clones, it was established that adipocyte differentiation markedly repressed T-antigen expression. The differentiation-specific repression of T-antigen expression did not result from a loss of proliferative potential associated with terminal differentiation, because it was observed in adipocytes that could be restimulated to proliferate. In such cells, restimulation of cell growth induced reactivation of T-antigen expression. Repression of T-antigen expression was also demonstrated during differentiation of SV40 T-antigen-immortalized human keratinocytes. These results establish that the process of cellular differentiation can repress T-antigen expression in at least two distinct biological systems.
Faster Rates for Policy Learning

This article improves the existing proven rates of regret decay in optimal policy estimation. We give a margin-free result showing that the regret decay for estimating a within-class optimal policy is second-order for empirical risk minimizers over Donsker classes, with regret decaying at a faster rate than the standard error of an efficient estimator of the value of an optimal policy. We also give a result from the classification literature that shows that faster regret decay is possible via plug-in estimation provided a margin condition holds. Four examples are considered. In these examples, the regret is expressed in terms of either the mean value or the median value; the number of possible actions is either two or finitely many; and the sampling scheme is either independent and identically distributed or sequential, where the latter represents a contextual bandit sampling scheme.
t-3-Isopropyl-1-methyl-r-2,c-6-diphenylpiperidin-4-one thiosemicarbazone.

The piperidine ring in the title compound, C(22)H(28)N(4)S, exhibits a chair conformation. The thiosemicarbazone moiety adopts an extended conformation, and the planar phenyl rings are oriented equatorially with respect to the piperidine ring. Two intermolecular hydrogen bonds involving the S atom form molecular pairs, and the crystal structure is stabilized by weak C-H.pi interactions in addition to van der Waals forces.
Insulin Insensitivity in Offspring of Parents with Type 2 Diabetes Mellitus

Measurements were made of the plasma glucose and insulin responses to a 75 g oral glucose challenge in 50 Chinese born in Taiwan, divided into two groups on the basis of family history of Type 2 diabetes. Twenty‐five individuals (age 29 ± 5 (±SD) years) had 2 parents with normal oral glucose tolerance, whereas at least 1 parent had Type2 diabetes in the other 25 subjects (age 30 ± 6 years). In addition, in vivo insulin action was estimated by determining the steady‐state plasma glucose concentration during a 3‐h continuous infusion of glucose, insulin, and somatostatin. Steady‐state plasma glucose concentration was used as a measure of insulin‐induced glucose disposal. The 50 subjects were non‐obese, and of comparable gender distribution and body mass index. Plasma glucose and insulin concentrations in response to oral glucose were similar in the two groups. However, the steady‐state plasma glucose concentration was significantly (p < 0.01) higher in offspring with a family history of Type 2 diabetes when compared by two‐way analysis of variance (mean ± SE was 5.87 ± 0.27 vs 5.12 ± 0.32 mmol I−1). This difference was found despite a significantly (p < 0.01) higher steady‐state plasma insulin concentration during the infusion studies (0.705 ± 0.027 vs 0.643 ± 0.025 nmol I−1) in offspring of people with diabetes. The results support the view that resistance to insulin‐stimulated glucose uptake is present in offspring of diabetic parents.
A Case Study of the Influence of Local Weather on Aedes aegypti (L.) Aging and Mortality

ABSTRACT: The survival rate of mosquitoes is an important topic that affects many aspects of decision-making in mosquito management. This study aims to estimate the variability in the survival rate of Ae. aegypti, and climate factors that are related to such variability. It is generally assumed that the daily probability of mosquito survival is independent of natural environment conditions and age. To test this assumption, a three-year fieldwork (2005–2007) and experimental study was conducted at Fortaleza-CE in Brazil with the aim of estimating daily survival rates of the dengue vector Aedes aegypti under natural conditions in an urban city. Survival rates of mosquitoes may be age-dependent and statistical analysis is a sensitive approach for comparing patterns of mosquito survival. We studied whether weather conditions occurring on a particular day influence the mortality observed on that particular day. We therefore focused on the impact of daily meteorological fluctuations around a given climate average, rather than on the influence of climate itself. With regard to survival time, multivariate analyses using the stepwise logistic regression model, adjusted for daily temperature, relative humidity, and saturated vapor pressure deficit (SVPD), suggest that age, the seasonal factor, and the SVPD were the most dependent mortality factors. Similar results were obtained using the Cox proportional hazard model, which explores the relationships between the survival and explanatory variables.
Childhood cancer patients' access to cooperative group cancer programs

The Children's Oncology Group (COG), a merger of the Children's Cancer Group (CCG) and the Pediatric Oncology Group (POG), conducts clinical trials for the treatment of childhood cancer. To assess the feasibility of developing a nationwide childhood cancer registry, the authors attempted to determine whether COG could serve as a resource for identifying all children with cancer.
Diabetes, Employment and Fatigue-Related Complaints: A Comparison Between Diabetic Employees, “Healthy” Employees, and Employees With Other Chronic Diseases

The work situation and fatigue-related complaints of employees with diabetes (N = 141) were compared with “healthy” employees (N = 8946) and employees with other chronic diseases (N = 1883). Baseline data from a Dutch Cohort Study on Fatigue at Work were used to test differences in background variables, work characteristics, lifestyle factors, and fatigue-related complaints. Odds ratios were calculated for prolonged fatigue, the need for recovery, burnout, and psychological distress. Results showed that employees with diabetes work more daytime hours and work less overtime than the other groups. If they have no comorbidity, they are no more likely to report fatigue-related complaints than “healthy” employees, except for a depressed mood. Comorbidity (the presence of one or more additional chronic diseases) is associated with increased fatigue-related complaints. Therefore, this group will need special attention from professionals.
Enhancing the Unified Features to Locate Buggy Files by Exploiting the Sequential Nature of Source Code

Bug reports provide an effective way for end-users to disclose potential bugs hidden in a software system, while automatically locating the potential buggy source files according to a bug report remains a great challenge in software maintenance. Many previous approaches represent bug reports and source code from lexical and structural information correlated their relevance by measuring their similarity, and recently a CNN-based model is proposed to learn the unified features for bug localization, which overcomes the difficulty in modeling natural and programming languages with different structural semantics. However, previous studies fail to capture the sequential nature of source code, which carries additional semantics beyond the lexical and structural terms and such information is vital in modeling program functionalities and behaviors. In this paper, we propose a novel model LS-CNN, which enhances the unified features by exploiting the sequential nature of source code. LSCNN combines CNN and LSTM to extract semantic features for automatically identifying potential buggy source code according to a bug report. Experimental results on widely-used software projects indicate that LS-CNN significantly outperforms the state-of-the-art methods in locating buggy files.
Inner Ear Fluid Volumes and the Resolving Power of Magnetic Resonance Imaging: Can it Differentiate Endolymphatic Structures?

Magnetic resonance imaging (MRI) can accurately recognize minute volumes as small as 1 mm3. The volumes of the utricle and saccule of the inner ear are within the resolving power of MRI, but these structures cannot be recognized because the endolymph and perilymph signals are identical. To clarify the interpretation and description of inner ear structures on MRI, we measured and calculated the volumes of the perilymphatic and endolymphatic spaces of the human ear. We found the total volume of the bony labyrinth to be approximately 192.5 mm3 (endolymph, 34.0 mm3; perilymph, 158.5 mm3).
Predicting soil heavy metal based on Random Forest model

The potential hazard of heavy metals in reclaimed mine soil has been attracted more and more attention. Hyperspectral inversion can be applied to predict the heavy metal content of the soil effectively. Three machine learning methods, Support Vector Machine (SVM), Random Forest (RF) and Extreme Learning Machine (ELM), are introduced in this paper, and then are compared with the Partial Least Squares (PLS) method. With the correlation analysis of heavy metal content and pretreatment spectral band, the models are constructed to predict the content of heavy metal in soil. The results show that the prediction results of machine learning methods are better than PLS, and ELM and RF are better than SVM. Analyzing the stability of the model, it can be found that the concentration of heavy metal samples will affect the prediction of ELM. Meanwhile, the stability of RF is the best than the other three models. RF algorithm has also the highest accuracy in the inversion of soil heavy metal research.