Miracle-dz/UniFAR-FTUs huggingface dataset:
Storytelling in Sustainable Tourism Management: Challenges and Opportunities for Slovenia

I n this paper the importance of storytelling in sustainable tourism management is introduced. It is argued that the development of storytelling as a destination marketing tool is related to the destination’s creative potentials. We discuss storytelling as a tool for sustainable tourism management and as an opportunity for tourism growth in the period of the experience economy. Apart from several remarkable results, the analysis of key indicators of Slovenian tourism shows some gaps. Intangible cultural heritage and cultural tourism digital demand are found as two important obstacles for higher tourism competitiveness. The paper points to the importance of the systemic institutional support to cultural and creative industries development in Slovenia. In this regard the provision of possibilities for acquiring creative and digital skills in tourism marketing education and training, adapted to the contemporary economic paradigm, are emphasized. Through the upgrading of storytelling project, Slovenia could develop, link and promote heterogeneous existent intangible cultural heritage and raise its international recognisability. 
Introducing a novel mushroom from mycophagy community with emphasis on biomedical potency

Mushrooms have been prized by humankind as medicine and culinary wonder since antiquity. Though several species are ethnically valued; many prospective species are still being discovered. One such wild macrofungus has recently been discovered during subsequent field surveys in West Bengal, India which in turn exposed as a traditionally consumed popular myco-food. The collected taxon was found to be unique with regard to its morphological as well as genetical features. After detailed characterizations, the fungus was identified as a novel taxon belonging to the genus Russula (Russulaceae, Basidiomycota). Besides, the investigation was further extended in search of new functional ingredients and in this context, a water soluble crude polysaccharide rich extract (Rusalan) was isolated from dried basidiocarps. Accumulating evidences from GC-MS, HPTLC, FT-IR along with several spectrophotometric methods postulated that the fraction consisted mainly of carbohydrate in triple helical conformation, where glucose was the major monosaccharide mostly with β-type glycosidic linkage. Conversely, Rusalan showed pronounced antioxidant activity in six in vitro assay systems with EC50 value ranging from 190–1328 μg/ml concentration. The crude polysaccharide was also evaluated against six bacterial strains using microdilution method and the growth of Staphylococcus aureus and Bacillus subtilis were found to be inhibited effectively. In addition, immune-stimulatory assays demonstrated that Rusalan could evidently promote proliferation, induce phagocytosis, release NO, produce intracellular ROS and upregulate mRNA expression of iNOS, TNF-α, COX-2, as well as IL-6 genes in in mouse macrophage cells. Therefore, aim of the present study was not only to describe a new taxon to the world mycoflora but also to introduce a potent therapeutic agent that could be explored for food and pharmaceutical purposes. However, isolation of active component and in vivo studies need to be designed further.
Shifting the distribution of risk: results of a community intervention in a Swedish programme for the prevention of cardiovascular disease.

STUDY OBJECTIVE: To examine the impact of a systematic risk factor screening and counselling carried out by family physicians and family nurses within the larger framework of a community intervention programme for the prevention of cardiovascular disease (CVD). DESIGN: Quasi-experimental study comparing trends in an intervention area with those in a reference area. SETTING: A Northern Sweden municipality (5500 inhabitants) constituted the intervention area while the Northern Sweden region (510,000 inhabitants) served as the reference area. PARTICIPANTS: All 30, 40, 50, and 60 year old inhabitants were invited each year from 1985 to 1992. Among 2046 eligible 1893 participated (92.5%), which formed eight independent cross sections. One cross section, 1986, was re-surveyed forming a panel. MAIN RESULTS: In the cross sections, mean total cholesterol was reduced from 7.09 to 6.27 mmol/l for men (p < 0.001) and from 7.13 to 5.89 mmol/l for women (p < 0.001) and mean systolic blood pressure from 132.2 to 123.7 mm Hg for men (p < 0.05) and from 129.2 to 122.0 mm Hg for women (p < 0.001) during the eight years. Body mass index (BMI) increased from 25.6 to 26.2 for men (p < 0.05) and from 25.0 to 25.5 for women (NS). A corresponding reduction in cholesterol and blood pressure (for women) occurred in the panel, while BMI was unchanged. The risk for CVD, using the Framingham equation, was estimated to be reduced overall by 19% (p = 0.0021) when comparing early cross sections (1985/86) with the later cross sections (1990/91). CONCLUSIONS: It was concluded that a long term community based CVD prevention programme that combines population and individual strategies can substantially promote a health shift in CVD risk in a high risk rural population. The individual attention and evaluation provided by the health provider survey seem to accelerate, but not increase the amount of, risk reduction.
Diversity of Tn1546-Like Elements in Vancomycin-Resistant Enterococci Isolated from Humans and Poultry in Korea

ABSTRACT To investigate the possible spread of vancomycin resistance among enterococci through horizontal gene transfer between two sources of vancomycin-resistant enterococci (VRE) isolated from farm animals and humans in Korea, molecular characterization of VRE isolated from poultry (20 isolates) and humans (35 isolates) was performed by PCR-restriction fragment length polymorphism typing of the vanA gene cluster (Tn1546). PCR mapping of Tn1546 finally distinguished seven different transposon types (types A to G). Type A was observed only in the poultry isolates, while the other six types were present only in the human isolates. An insertion sequence and deleted sequence were detected in most of the human isolates in the orf2-vanR and vanX-vanY regions in the Tn1546-like element, but not in the poultry isolates. Tn1546-like elements were found in conjugal plasmids of most human VRE, whereas they were detected in the chromosomes of all poultry VRE. Accordingly, no evidence was found of any recent transmission of vancomycin resistance genes between poultry and humans in Korea.
Client Satisfaction with Family Planning Services and Associated Factors in the Rural Public Health Centers of Kucha District, Southern Ethiopia

Background: Client satisfaction is considered as one of the factors that influence the use of family planning and other reproductive health services. It is very important to improve utilization of the service. Despite this importance, satisfaction still has been ignored by health care managers. Objective: The main aim of this study was to assess the level of client satisfaction with family planning service in public health centers and identify factors associated with client satisfaction in Kucha district, Gamo Gofa Zone, South Ethiopia. Methods: Facility based cross -sectional study was conducted from July 1-21, 2017 with 538 family planning service users. Respondents were selected by using systematic random sampling from four randomly selected rural health centers in the district. Data was collected by using pre-tested structured questionnaire and analyzed by SPSS version 20.0. Four diploma nurses collected the data and two B.Sc nurses supervised the data collection process. Logistic regression analyses were conducted and statistically significant association was declared at P value <0.05. Result: About 68.4% of the clients were satisfied with the service they received. Multivariable logistic regression analysis indicated that respondents with age 35 and above years [AOR (95% CI)=3.006 (1.308,6.911)], respondents who attended secondary cycle (5-8) [AOR (95% CI)=2.716 (1.377,7.817)], those for whom privacy was ensured [AOR (95% CI)=1.771 (0.738, 4.252 )], clients who received respect and friendly approach from other clinic staffs [AOR (95% CI)=6.871 (3.344,14.116)], those who reported convenient clinic opening hour [AOR (95% CI)=6.288 (2.865,13.801)] and those who got adequate information [AOR (95% CI)=5.043 (2.362,10.767)] shows significant association with the outcome variable. Conclusions and recommendations: In this study, client satisfaction is slightly high. Predictors of clients’ satisfaction with family planning service in this study were age, educational level, adequacy of information to clients, convenience of clinic opening hours, respect and friendly approaches from other clinical staffs and maintenance of privacy. Appropriate Information, education and communication is needed to solve the problem.
Fusing eye movements and observer narratives for expert-driven image-region annotations

Human image understanding is reflected by individuals' visual and linguistic behaviors, but the meaningful computational integration and interpretation of their multimodal representations remain a challenge. In this paper, we expand a framework for capturing image-region annotations in dermatology, a domain in which interpreting an image is influenced by experts' visual perception skills, conceptual domain knowledge, and task-oriented goals. Our work explores the hypothesis that eye movements can help us understand experts' perceptual processes and that spoken language descriptions can reveal conceptual elements of image inspection tasks. We cast the problem of meaningfully integrating visual and linguistic data as unsupervised bitext alignment. Using alignment, we create meaningful mappings between physicians' eye movements, which reveal key areas of images, and spoken descriptions of those images. The resulting alignments are then used to annotate image regions with medical concept labels. Our alignment accuracy exceeds baselines using both exact and delayed temporal correspondence. Additionally, comparison of alignment accuracy between a method that identifies clusters in the images based on eye movement vs. a method that identifies clusters using image features suggests that the two approaches perform well on different types of images and concept labels. This suggests that an image annotation framework should integrate information from more than one technique to handle heterogeneous images. We also investigate the performance of the proposed aligner for dermatological primary morphology concept labels, as well as for lesion size or type and distribution-based categories of images.
[Etiological characteristics of influenza A (H1N1) 2009 virus in Beijing].

OBJECTIVE To analyze the results of detection on influenza A (H1N1) 2009 virus in Beijing from May 2009 to December 2009 and to understand the epidemiologic characteristics during the pandemic period. METHODS The study was conducted from the May 1 to December 27, 2009. A total of 101 852 throat swab samples were detected with the real-time RT-PCR assay by the Beijing Network Laboratory. Data was statistically analyzed. RESULTS 9843 samples showed influenza A (H1N1) 2009 positive, with an overall positive rate as 9.66%. In terms of the positive rates, they were 2.85% from May to June, 3.32% from July to August and 8.35% from September to October. The peak month fell in November (29.67%) and December (24.33%). The positive rates among the following subpopulations were: 8.40% among the suspected cases, 4.75% among close contact cases, 11.46% among the influenza-like illness cases and 7.33% among the cluster cases with fever. Positive cases mainly fell in age groups 5 - 14 and 15 - 24. The ratio of male to female was 1.5:1. CONCLUSION During the pandemic period of influenza A (H1N1) 2009, positive cases gradually increased during May to November but slowly decreasing in December.
Type 2 Neural Progenitor Cell Activation Drives Reactive Neurogenesis after Binge-Like Alcohol Exposure in Adolescent Male Rats

Excessive alcohol consumption during adolescence remains a significant health concern as alcohol drinking during adolescence increases the likelihood of an alcohol use disorder in adulthood by fourfold. Binge drinking in adolescence is a particular problem as binge-pattern consumption is the biggest predictor of neurodegeneration from alcohol and adolescents are particularly susceptible to the damaging effects of alcohol. The adolescent hippocampus, in particular, is highly susceptible to alcohol-induced structural and functional effects, including volume and neuron loss. However, hippocampal structure and function may recover with abstinence and, like in adults, a reactive burst in hippocampal neurogenesis in abstinence may contribute to that recovery. As the mechanism of this reactive neurogenesis is not known, the current study investigated potential mechanisms of reactive neurogenesis in binge alcohol exposure in adolescent, male rats. In a screen for cell cycle perturbation, a dramatic increase in the number of cells in all phases of the cycle was observed at 7 days following binge ethanol exposure as compared to controls. However, the proportion of cells in each phase was not different between ethanol-exposed rats and controls, indicating that cell cycle dynamics are not responsible for the reactive burst in neurogenesis. Instead, the marked increase in hippocampal proliferation was shown to be due to a twofold increase in proliferating progenitor cells, specifically an increase in cells colabeled with the progenitor cell marker Sox2 and S-phase (proliferation) marker, BrdU, in ethanol-exposed rats. To further characterize the individual subtypes of neural progenitor cells (NPCs) affected by adolescent binge ethanol exposure, a fluorescent quadruple labeling technique was utilized to differentiate type 1, 2a, 2b, and 3 progenitor cells simultaneously. At one week into abstinence, animals in the ethanol exposure groups had an increase in proliferating type 2 (intermediate progenitors) and type 3 (neuroblast) progenitors but not type 1 neural stem cells. These results together suggest that activation of type 2 NPCs out of quiescence is likely the primary mechanism for reactive hippocampal neurogenesis following adolescent alcohol exposure.
Detection of cervical intraepithelial neoplasia by using optical coherence tomography in combination with microscopy

Abstract. Optical coherence tomography (OCT) is a noninvasive high-resolution imaging technique that permits the detection of cancerous and precancerous lesions of the uterine cervix. The purpose of this study was to evaluate a new system that integrates an OCT device into a microscope. OCT images were taken from loop electrosurgical excision procedure (LEEP) specimens under microscopic guidance. The images were blinded with respect to their origin within the microscopic image and analyzed independently by two investigators using initially defined criteria and later compared to the corresponding histology. Sensitivity and specificity were calculated with respect to the correct identification of high-grade squamous intraepithelial lesions (HSIL). The interinvestigator agreement was assessed by using Cohen’s kappa statistics. About 160 OCT images were obtained from 20 LEEP specimens. Sixty randomly chosen images were used to define reproducible criteria for evaluation. The assessment of the remaining 100 images showed a sensitivity of 88% (second investigator 84%) and a specificity of 69% (65%) in detecting HSIL. Surgical microscopy-guided OCT appears to be a promising technique for immediate assessment of microanatomical changes. In the gynecological setting, the combination of OCT with a colposcope may improve the detection of high-grade squamous intraepithelial lesions.
Sensitivity of bacteria to diamond nanoparticles of various size differs in gram-positive and gram-negative cells.

In this study, the influence of the size and surface termination of diamond nanoparticles (DNPs) on their antibacterial activity against Escherichia coli and Bacillus subtilis was assessed. The average size and distribution of DNPs were determined by dynamic light scattering and X-ray diffraction techniques. The chemical composition of the DNPs studied by X-ray photoelectron spectroscopy showed that DNPs > 5 nm and oxidized particles have a higher oxygen content. The antibacterial potential of DNPs was assessed by the viable count method. In general, E. coli exhibited a higher sensitivity to DNPs than B. subtilis. However, in the presence of all the DNPs tested, the B. subtilis colonies exhibited altered size and morphology. Antibacterial activity was influenced not only by DNP concentration but also by DNP size and form. Whereas untreated 5-nm DNPs were the most effective against E. coli, the antibacterial activity of 18-50-nm DNPs was higher against B. subtilis. Transmission electron microscopy showed that DNPs interact with the bacterial surface, probably affecting vital cell functions. We propose that DNPs interfere with the permeability of the bacterial cell wall and/or membrane and hinder B. subtilis colony spreading.
An analysis of nursing and medical students' attitudes towards and knowledge of complementary and alternative medicine (CAM).

AIMS AND OBJECTIVES This study aims to evaluate and compare nursing and medical students' attitudes and knowledge about complementary and alternative medicine (CAM). BACKGROUND Despite increased popularity of the use of complementary and alternative medicine, it is not included in nursing and medicine schools' curricula in many countries. DESIGN A cross-sectional design was used. METHOD This study's research population included 972 students who were educated at a school of nursing and a faculty of medicine during the academic year 2006-2007. The study used a questionnaire the researchers prepared as data collection form. Pearson chi-square test was used to observe the differences between nursing and medical students. A p-value <0.05 was accepted statistically significant. RESULTS The population was 49.1% nursing students and 50.9% medical students. Of the nursing students, 57.8% agreed with the statements that complementary and alternative medicine modalities should be integrated into clinical practice, 61.3% agreed for curriculum. Of the medical school students, 32.6% agreed for clinical practice and 37.9% for curriculum. The nursing students had sufficient knowledge of mostly massage and imagery; and medical students had sufficient knowledge of mostly diet therapy, vitamins and prayer. CONCLUSIONS The results of current study reveal that nursing students adopt more positive attitudes than medical students towards complementary and alternative medicine therapies and that both student groups have limited knowledge of complementary and alternative medicine modalities. RELEVANCE TO CLINICAL PRACTICE Physicians and nurses play important roles in helping patients use complementary and alternative medicine safely and accurately. Therefore, as future nurses and physicians, nursing and medical students should have sufficient knowledge of and education on complementary and alternative medicine modalities. In this context, handling complementary and alternative medicine on a scientific scale and including it in nursing and medical students' educational programmes should be among the goals and plans in Turkey.
CMOS transimpedance amplifier for DVD applications

This paper presents a design of wideband transimpedance amplifier applied in optical storage systems. The expansion of amplifier bandwidth is due to the combination of current-voltage and voltage amplifiers, as well as parasitic capacitance compensation. With 0.35 /spl mu/m digital CMOS technology, the transimpedance gain is 9.5 dB /spl Omega/ and f/sub -3dB/ bandwidth is 215 MHz respectively. Group delay with /spl plusmn/0.5 ns variation can achieve bandwidth of 160 MHz. The occupied area of improved TIA is 240/spl times/190 /spl mu/m/sup 2/.
Detection of hepatitis B virus DNA in serum is rare in the absence of hepatitis B surface antigen: impacts for detection and monitoring of chronic hepatitis B.

Sir, Hepatitis B (HBV) is one of the most common infectious diseases worldwide, with 2 billion people having evidence of past or present infection worldwide and over 200,000 chronically infected in Australia alone. It has been estimated that in 2010 there were 312,400 deaths due to HBV-associated cirrhosis worldwide. Serological testing is the gold standard for diagnosis, with detection of hepatitis B surface (HBsAg) and envelope antigen (HBeAg) consistent with active replicating virus, and antihepatitis B surface antibody (anti-HBs Ab) found following successful immunisation or control of natural infection. Over time it has become clear that loss of HBsAg with or without the development of anti-HBs Ab does not represent ‘clearance’ of HBV as previously thought. In some patients, low level viral replication within the liver may persist associated with, or in the absence of, low level detectable HBV DNA in the serum. The prevalence of so called ‘occult HBV’ varies geographically but was found in 5–10% of European blood donors with isolated anti-hepatitis B core Ab. The long-term clinical impacts have not yet been determined but these patients are at risk of HBV reactivation in the setting of immunosuppression. Quantification of HBV DNA is used to confirm the presence of circulating HBV and to monitor and guide treatment of chronic HBV, but its ability to predict HBsAg re-emergence and active hepatitis in the setting of immunosuppression remains undefined. Due to a perceived increase in requests for HBV DNA testing in patients traditionally thought at low risk for active HBV (HBsAg negative, anti-HBs Ab positive) a retrospective review of HBV DNA testing was performed to provide local data as to the reliability of serological and biochemical markers as predictors of HBV DNA positivity, and thus guide its ongoing use. All patients who had HBV DNA quantification at the Alfred Hospital from September 2008 to September 2010 were identified from the laboratory records and included. The Alfred Hospital is an adult tertiary referral centre with large hepatology, haematology and infectious diseases units. It is the state referral centre for the management of HIV and performs a number of solid organ and haematological transplants each year. Study information was collected from the electronic pathology system and included age, gender, serological testing and the result of HBV DNA including viral load when positive. Only serological testing performed at the Alfred Hospital and ordered on the same day or prior to the HBV DNA was recorded (i.e., the results that would be available to the laboratory or physician when ordering the test). The most recent liver function test, specifically albumin, gamma-glutamyl transferase (GGT) and alanine aminotransferase (ALT), were recorded, as was the patient’s hepatitis C (HCV) and HIV sero-status and the medical specialty of the
7A-1 SURF Imaging - A New Method for Ultrasound Contrast Agent Imaging

A new method for detection of ultrasound contrast agent micro-bubbles is presented and analyzed. The method transmits dual frequency pulse complexes (frequency separation ~ 1:10), and the signals from at least two complexes with opposite polarity of the low frequency pulse is combined to suppress the signal scattered from tissue and enhance the signal scattered from micro-bubbles. The method has larger CTR and CNR than current methods using the 2nd harmonic band of the scattered signal, especially for the high frequency above the bubble resonance frequency. The methods have special interest for high frequency imaging of neo-angiogenesis in tumors and the vasa vasorum of arterial plaque.