Miracle-dz/UniFAR-FTUs huggingface dataset:
Stoichiometric Boron-Based Nanostructures

The elemental boron and boron-containing compounds hold a unique place in chemistry, physics, and materials science (Greenwood, 1973; Donohue, 1974; Matkovich, 1977; Emin, 1987; Albert & Hillebrecht, 2009). In general, they are composed of various multi-atom boron clusters, such as graphitic layer, octahedral B6 and icosahedral B12, among which the 12-atom B12 icosahedral cluster is the most common form (Greenwood, 1973; Donohue, 1974; Matkovich, 1977; Emin, 1987; Albert & Hillebrecht, 2009). The electronic properties of these boron clusters are characterized by the three-center electron-deficient bond, which presents some analogy with metallic bonding because electron deficiency forces electrons to be shared at the cluster surface(Greenwood, 1973; Donohue, 1974; Emin, 1987). Whereas these clusters are linked together by two-center covalent bonds, which lead to the intra-cluster and inter-cluster bonds have comparable strength (Greenwood, 1973; Donohue, 1974; Emin, 1987; Nelmes et al., 1995; Vast et al., 1997; Fujimori et al., 1999). These features make boronbased materials exhibit a wide variety of electronic properties ranging from semiconducting to superconducting. Furthermore, the boron clusters as structural units may be stacked in many different ways. This fact, coupled with the small size and high affinity of boron atoms, make boron-related materials form a unique family with an astonishing number of members.
High-sensitivity and large-dynamic-range fiber refractometer based on composite-cavity Fabry-Perot structure

Most sensors have the tradeoff dilemma of high sensitivity and large dynamic range. We demonstrate here an all-fiber refractive index sensor based on a composite intrinsic Fabry-Perot interferometer (FPI), which possesses the co-existence advantages of high sensitivity and large dynamic range. Experimental trends are in good agreement with the theoretical predictions. The co-existence of high sensitivity and large dynamic range in a composite FPI is of great significance to practical refractive index measurement.
A novel T-shaped slot PIFA for MIMO applications

Because of rapidly increasing demand for high capacity communication services compact antennas have become center of research interest nowadays and this reduction of size becomes much more important especially when we want to use the multiple-input multiple-output (MIMO) technology; to increase channel capacity, in modern compact devices. Microstrip antennas are an attractive option due to low cost, and small size. However to fulfill need for more compact and miniaturized devices; a dual feed dual element planar inverted-F antenna (PIFA) at 2.45GHz has been proposed on a very small PCB (60 mm × 20 mm × 0.8 mm), to be used for ISM 2.45 GHz band. While total volume occupied by two antennas is 10 mm × 20 mm × 2.5 mm. −10 dB return loss or VSWR=2 criterion for required bandwidth has been satisfied, only with help of designing a novel radiation structure. To miniaturize size of PIFA a novel T-shaped slot has been employed in radiation structure. Overall size is compact than small MIMO antennas, available in open literature. As the proposed design is suitable for different feeding environments, it can be used in different small size PCB devices, for different applications. Results show satisfactory bandwidth, and omnidirectional radiation pattern.
Isolation and Characterization of New Proliferating Cell Nuclear Antigen (POL30) Mutator Mutants That Are Defective in DNA Mismatch Repair

ABSTRACT A number of studies have suggested a role for proliferating cell nuclear antigen (PCNA) in DNA mismatch repair (MMR). However, the majority of mutations in the POL30 gene encoding PCNA that cause MMR defects also cause replication and other repair defects that contribute to the increased mutation rate caused by these mutations. Here, 20 new pol30 mutants were identified and screened for MMR and other defects, resulting in the identification of two mutations, pol30-201 and pol30-204, that appear to cause MMR defects but little if any other defects. The pol30-204 mutation altered an amino acid (C81R) in the monomer-monomer interface region and resulted in a partial general MMR defect and a defect in MSH2-MSH6 binding in vitro. The pol30-201 mutation altered an amino acid (C22Y) located on the surface of the PCNA trimer that slides over the DNA but did not cause a defect in MSH2-MSH6 binding in vitro. The pol30-201 mutation caused an intermediate mutator phenotype. However, the pol30-201 mutation caused almost a complete defect in the repair of AC and GT mispairs and only a small defect in the repair of a “+T” insertion, an effect similar to that caused by an msh6Δ mutation, indicating that pol30-201 primarily effects MSH6-dependent MMR. The chromosomal double mutant msh3-FF>AA msh6-FF>AA eliminating the conserved FF residues of the PCNA interacting motif of these proteins caused a small (<10%) defect in MMR but showed synergistic interactions with mutations in POL30, indicating that the FF>AA substitution may not eliminate PCNA interactions in vivo. These results indicate that the interaction between PCNA and MMR proteins is more complex than was previously appreciated.
Microsatellite instability in endometrial carcinomas: Frequent replication errors in tumors of early onset and/or of poorly differentiated type

Endometrial and ovarian carcinomas are common among women belonging to hereditary nonpolyposis colorectal carcinoma (HNPCC) families; tumors developing in them are characterized by genetic instability due to an inherited dysfunction of the DNA‐mismatch‐repair system. To clarify the role of similar genetic factors in sporadic forms of gynecological tumors, we examined 77 endometrial and 68 ovarian carcinomas for replication error (RER) at five microsatellite loci. RER‐positive phenotypes at two or more microsatellite loci were observed in 18 of the endometrial carcinomas, but in only two of the ovarian carcinomas. Among the patients with endometrial carcinomas, the frequency of RER tended to be higher in those under age 50 than in those over age 60. Furthermore, RER was significantly more frequent in poorly differentiated than in well‐differentiated tumors (P = 0.008, Fisher's exact test). These data suggest that genetic factors characterized by RER are likely to play an important role in some endometrial carcinomas, particularly those of early onset and/or of the poorly differentiated type.
What Predicts Retention on an In-Prison Drug Treatment Program?

The effectiveness of treatments for substance use disorders is strongly related to retention, since early dropout from treatment is associated with greater likelihood of relapse. The purpose of this prospective, ex post facto study is to analyze the effect of individual variables on retention in a treatment program carried out in a prison drug-free unit. The Addiction Severity Index, motivation and personality profile of fifty inmates were assessed on entry to the prison. Inmates were monitored for a year to identify length of stay. Results: Motivation variables at intake play a vital role in the prediction of retention in a prison drug-free unit; scores on the Aggressive-Sadistic and Narcissistic scales are also strong predictors of treatment retention. La eficacia de los tratamientos para los trastornos por uso de sustancias está altamente relacionada con la retention, pues entre otras cosas el abandono del tratamiento se vincula con una mayor probabilidad de recaída. El propósito de este estudio prospectivo ex post facto es analizar el efecto de distintas variables individuales sobre la retención en el tratamiento dispensado en una unidad libre de drogas intrapenitenciaria. Cincuenta internos de este programa fueron evaluados al ingreso en variables relacionadas con el perfil de gravedad de la adicción, la motivación y la personalidad. Resultados: La motivación inicial es una variable fuertemente predictora de la retención en el tratamiento, tanto a los seis meses como al año de estancia. Asimismo, las escalas Narcisista y Agresivo-Sádica evaluadas por el instrumento MCMI-II también tuvieron capacidad pronóstica en la retención.
Affective spatial compatibility task (AFFSCT): theory and applications

Emotional stimuli are processed very effi ciently, infl uencing physiological and behavioral responses as well as attention, perceptual processes and sensory-motor integration. In a previous work, we introduced a new paradigm, the Affective Spatial Compatibility task (AffSCt), to study whether the affective valence of the stimulus infl uences spatial compatibility effects. By using fi gures of soccer players of Favorite and Rival Teams as positive and negative valence stimuli, we found a normal Spatial Compatibility effect for the Favorite team and a reversed one for the Rival team. Here, we analyzed the time course of inhibitory and facilitatory effects of emotional valence by the Vincentization method. We found that for Favorite team, the facilitatory effect for the compatible condition, as compared to the incompatible one,
Mammaglobin : A novel tumor marker for breast cancer

Breast cancer is a major problem among females all over the world. Despite apparent curative resection, subsequent development of metastatic spread presents a major clinical problem in about 30% of all breast cancer patients. The aim of this study was to investigate the clinical reliability of mammaglobin m-RNA (MAG m-RNA) as a marker of circulating cancer cells in breast cancer patients and to study the relevance of its expression in blood and expression of its protein in breast tissues, with the pathological parameters and its value in evaluating efficiency of treatment. This study was conducted on 48 breast cancer patients and 28 controls (10 healthy controls and 18 patient controls: 6 with fibroadenoma, 4 with uterine carcinoma, 4 with ovarian carcinoma and 4 with colon cancer). For histopathological study, the healthy control group included the normal breast tissue adjacent to fibroadenoma. All breast cancer patients were of the infiltrating ductal carcinoma type and 10 of them had associated areas of intraductal carcinoma. The patient group was classified into 26 patients with localized breast cancer and 22 patients with metastases (9 patients had axillary lymph node metastases and 13 patients had distant metastases). Breast cancer patients were reclassified according to the histologic grade into grade I (8 patients), grade II (26 patients) and grade III (14 patients). All individuals included in this study were subjected to detection of MAG m-RNA in circulating tumor cells in peripheral blood using nested PCR technique. Breast tissue expression of MAG was investigated using immunohistochemistry. Blood and tissue MAG expression were correlated with estrogen receptor and Ki-67 proliferation index. Circulating MAG m-RNA is a highly specific (100%) tumor marker. The detection rate was significantly associated with the histologic grades, ER positivity and low proliferative rate of tumors. The detection rate declines after receiving chemotherapy. Immunohistochemically, the pattern of expression of MAG in breast cancer tissues was characteristically different than that in non-cancer tissues (being diffuse cytoplasmic in the former and scattered in the latter). MAG overexpression in breast tissue was significantly higher in low grade tumors (I and II) than in high grade ones (III). The strong staining intensity was more frequently detected in low grade tumors. Also MAG expression in breast tissue was significantly correlated with ER positivity and low Ki67 proliferation index of the tumors. MAG is a promising specific tumor marker of breast cancer that could predict the prognosis of breast cancer and its response to hormonal treatment. [Turk J Cancer 2007;37(3):89-97]
Factors affecting radiographers' organizational commitment.

CONTEXT A variety of factors influence employees' attitudes toward their workplace and commitment to the organization that employs them. However, these factors have not been well documented among radiologic technologists. OBJECTIVE To determine the predictive ability of selected organizational, leadership, work-role and demographic variables on organizational commitment for a national sample of radiographers. METHODS Three thousand radiographers registered by the American Registry of Radiologic Technologists working full time in clinical settings were surveyed by mail regarding their commitment to their employers, leadership within the organization that employs them, employer support and demographic information. RESULTS Overall, radiographers were found to have only a moderate level of commitment to their employers. Among the factors that significantly affected commitment were the radiographer's educational level, perceived level of organizational support, role clarity and organizational leadership. CONCLUSION The results of this study could provide managers and supervisors with insights on how to empower and challenge radiographers and offer opportunities that will enhance radiographers' commitment to the organization, thus reducing costly turnover and improving employee performance.
Non‐progressive psychomotor retardation in a child with severe deficiency of arylsulphatase A activity

Severe deficiency of arylsulphatase A (ARSA) activity was detected in a boy with delayed psychomotor development, coarse face and liver enlargement when he was aged 2. The case does not fit into the description of the Metachromatic leukodystrophy (MLD) proposed by Hagberg (1963) mainly because he did not deteriorate. Twelve years of follow up did not show any signs of decerebration or further intellectual decline; only speech was, and still is, absent.
THE EFFECTS OF IONS ON THE BINDING OF AGONISTS AND ANTAGONISTS TO MUSCARINIC RECEPTORS

1 There are no selective effects of Na+, K+, Ca2+, Mg2+ or Cl− on the binding of antagonists or agonists to muscarinic receptors in rat brain. A decrease in affinity related to ionic strength is found for all these ions. 2 Larger effects were produced by T+, La3+, and some transition metal ions.
Development of cerebral lateralisation for recognition of emotions in chimeric faces in children aged 5 to 11

In contrast to research into the development of language laterality, there has been relatively little research into the development of lateralisation of emotional processing. If language lateralisation begins in childhood and is complete by puberty (Lenneberg, 1967) it seems reasonable that the lateralisation of the perception of emotions might also occur during this period. In this study a split field chimeric faces test using the six universal facial expressions proposed by Ekman and Friesen (1971), an emotion in the eyes test, and a situational cartoon test were administered to three groups of children aged 5/6, 7/8, and 10/11. No overall hemispace advantage was seen for the 5/6-year-old group, but by the age of 10/11 a clear left hemispace advantage (right hemisphere) was found for all six emotions. Such a pattern is comparable to a previous study that made use of adults on this task (Workman, Peters, & Taylor, 2000b). Moreover, a significant positive correlation between a child's ability to recognise emotions in cartoon situations and their left hemispatial advantage score was uncovered. Finally, a significant positive correlation between a child's ability to recognise emotions in the eyes of others and their left hemispatial advantage score was also uncovered. These findings are taken as evidence that there may be a relationship between the development of emotional processing in the right hemisphere and a child's emerging ability to perceive or attend to the emotional states of others. Results are discussed in relation to the child's development of a theory of mind.
Efficacy of alpha interferon therapy for lamivudine resistance in chronic hepatitis B

Objectives: The occurrence of lamivudine resistance is often associated with the clinical breakthrough, which is characterised by the reappearance of hepatitis B virus (HBV) DNA in serum and the elevation of aminotransferases. We evaluated the efficacy of alpha interferon for clinical breakthrough in patients receiving lamivudine therapy.
An 84.6-dB-SNDR and 98.2-dB-SFDR Residue-Integrated SAR ADC for Low-Power Sensor Applications

This paper presents an asynchronous-clocking successive approximation register (SAR) analog-to-digital converter (ADC) suitable for ultralow-power fine-precision sensor applications whose signal bandwidth is in the kilohertz range. The performance-limiting issues of comparator noise and capacitor mismatch in SAR ADC are resolved by a residue integration scheme combined with a dynamic element matching (DEM), achieving a high resolution without imposing extra burden on the design of residue amplifier and comparator. The prototype 16-bit 2 kS/s SAR ADC is fabricated using 180-nm CMOS process in an area of 0.68 mm2. Measurements show 84.6-dB signal to noise and distortion ratio and 98.2-dB spurious-free dynamic range at the Nyquist input frequency. The ADC dissipates 7.93 $\mu \text{W}$ from supply voltage of 1.8 V and achieves a Schreier figure of merit of 165.6 dB.
An intercomparison campaign of ground-based UV-visible measurements of NO2, BrO, and OClO slant columns: Methods of analysis and results for NO2

[1] Within the framework of the Network for the Detection of Stratospheric Change (NDSC), an intercomparison campaign of ground-based zenith-sky viewing UV-visible spectrometers was held at the Andoya Rocket Range (69°N, 16°E) at Andenes, Norway, from February 12 to March 8, 2003. The chosen site is classified as a complementary NDSC site. Eight groups from seven countries participated in the campaign which focused on the measurements of slant columns of NO 2 , BrO, and OClO. This first campaign publication concentrates on measurements of the NO 2 slant columns. Different analysis criteria were investigated during the campaign. These included the use of fitting parameters as chosen by each group to provide what they considered to be optimized retrievals. Additional sets of parameters, imposed for all the groups, were also used, including the wavelength interval, absorption cross sections, and species fitted. Each instrument's results were compared to the measurements of selected reference instruments, whose choice was based on a technique combining regression analysis and examination of the residuals with solar zenith angle. Considering the data obtained during the whole campaign for solar zenith angles between 75° and 95°, all instruments agreed within 5% in the case of NO 2 with imposed analysis parameters in the 425-450 nm region. Measurements agree less well when retrieving the NO 2 slant columns in the 400-418 nm region or when using parameters optimized by each investigator for their instrument.
Initial response to portoenterostomy determines long-term outcome in patients with biliary atresia.

PURPOSE The aim of this study was to assess the efficacy of portoenterostomy in biliary atresia and determine factors that predict outcomes. METHODS The outcomes after portoenterostomy for biliary atresia from 1976 to 1996 were graded into 3 defined groups: G (good, jaundice free); I (intermediate, progressive liver disease with liver transplant if needed after 3 years of age); P (poor, liver transplant or death at less than 3 years of age). RESULTS Twenty-seven of 49 children (55%) who underwent portoenterostomy responded. Of these, 13 (26%) were jaundice free (G). Of 14 children (28%) in I, 6 underwent liver transplant after 3 years of age. Of 22 children (44.8%) in P, 14 (28%) died before 3 years and 8 underwent liver transplant before 3 years. Thus, 42% of the children in this series are surviving with native liver. Age at operation in P was significantly different compared with G. Preoperative values of bilirubin and alanine transaminase were comparable in the 3 groups. Postoperative values of bilirubin and alanine transaminase were lower in G and I compared with P Complications were significantly lower in group G. CONCLUSIONS Portoenterostomy alone in biliary atresia is beneficial in 40% of cases. Factors associated with the outcome include age at operation, postoperative cholangitis, and change in values of bilirubin and alanine transaminase. A classification based on decline of bilirubin and enzyme levels 3 months after portoenterostomy is proposed to predict the long-term outcome of an individual case of biliary atresia. It is particularly relevant in the intermediate group in which timing of referral may preclude or compromise liver transplant.
Why Challenge the Ivory Tower? New Evidence on the Basicness of Academic Patents*

While often presumed in academic literature and policy discussions there is little empirical evidence showing that academic patents protect more basic inventions than corporate patents. This study provides new evidence on the basicness of academic patents using German professor patents linked to patent opposition data from the European Patent Office (EPO). Patent oppositions are the most important mechanism by which the validity of patents filed at the EPO can be challenged. Controlling for patent value, asymmetric information and diverging expectations between the opposition parties, the likelihood of a potentially litigious situation and the relative costs of opposition versus settlement, we find that academic patents are opposed less frequently than a control group of corporate patents. This suggests that academic patents cover rather basic inventions with a low immediate commercial value not threatening current returns of potential plaintiffs. The effect is weaker for academic patents in collaboration with the business sector, which suggests that those patents are evaluated as more applied by owners of potentially rival technologies.
Labeling of mixed leukocytes with (99m)Tc-HMPAO causes severe chromosomal aberrations in lymphocytes.

UNLABELLED 99mTc-d,1-hexamethylpropyleneamine oxime (HMPAO) is widely used as a labeling agent for leukocytes in the diagnosis of inflammatory or infectious foci. Cytotoxicity studies have indicated that intracellular labeling of leukocytes with (111)In compounds may have severe detrimental effects on the cells. METHODS In this study, the radiotoxic effects on mixed lymphocytes after labeling with (99m)Tc-HMPAO was investigated using the cytokinesis-blocked micronucleus assay and chromosomal aberration assay. RESULTS Whereas negligible numbers of chromosome abnormalities were noted in unlabeled lymphocytes, the labeled lymphocytes showed multiple aberrations of various types, including dicentric, tricentric, and fivecentric chromosomes; centric rings; chromosome and chromatid type breaks; and acentric fragments. CONCLUSION Heavily aberrant lymphocytes are seen in (99m)Tc-HMPAO-labeled mixed leukocytes after routine clinical procedures. It is unlikely, however, that this would cause detrimental effects, such as lymphoid malignancy, as these cells would normally be eliminated through apoptosis or phagocytosis.