Miracle-dz/UniFAR-FTUs huggingface dataset:
Groundwater monitoring for evaluating the pasture carrying capacity and its vulnerability in arid and semi-arid regions: A case study of urban and mining areas in Mongolia

Arid and semi-arid regions cover 41% of the global land area and 2 billion people, 90% of which belong to developing countries, live there. Variation in precipitation due to climate change brings big large influences on ground and underground water resources, and especially it is predicted that arid and semi-arid regions are getting drier. Therefore, it is imperative to clarify impacts to environmental vulnerability caused by the variation of water cycle (VWC) due to climate change and consider options for its adaption. Mongolia is a typical country where environmental vulnerability is getting worse by VWC. Our previous studies revealed that the increase of evapotranspiration and permafrost degradation by global warming deteriorate the pasture carrying capacity (PCC) in semi-arid regions in Mongolia. In this manner, VWC is a key component of PCC, but VWC depends on not only climate change but also human activities. Recent mine development and urbanization, as well as growth of livestock, increase groundwater use, but their influences have not been clarified. To explore the influence of urbanization and mining, we have started groundwater monitoring of urban areas in semi-arid regions (Northern Mongolia) and mining areas in arid regions (Southern Mongolia) since May 2018. After investigating hundreds of wells in those areas, and finally selected 11 wells in urban areas and 7 wells in mining areas for groundwater monitoring. 22 Onset HOBO U20 Water Level Loggers (Forestry Suppliers, Inc.), including 5 Loggers for atmospheric correction, and a Water Flow Rate Sensor (Keyence Inc.) are working for measuring groundwater usage. Meanwhile, with data analyses of groundwater level at 875 wells from 2015 to 2017 measured by the local basin authority, it was found that the groundwater level of mining area had a tendency of decreasing widely comparing with that of non-mining area.
FROM COOPERATION OF PARENTS AND EDUCATORS TOWARDS EMPOWERING PARTNERSHIP

Background. Partnership in this thesis is interpreted as the responsibility of children education which is taken by the members and their activity. The main role of the partners is to organize the environment of preschool education for children to use their prior knowledge and experience to understand new information and meaningful context. Methods. Two questionnaires were included in this research, 191 parents and 199 educators were questioned. Results. Educators and parents generally see the purpose of preschool education institution to stimulate the child’s social and cognitive development (88.9%) and considerably rarely the purpose is related to meeting the natural needs of a child (32.2%). Educators more often than parents thought that it was necessary to strengthen the education of parents in partnership with their children’s education (p < .001). Mutual ambition to collaborate (67.3%), better education of parents (49.2%), the maintenance of permanent connection (41.7%), information exchange (49.7%) and better confidence in each other (45.7%) would be helpful in seeking for more effective cooperation. Conclusions. Only a small percentage of parents understand that preschool education is most important to meet the natural needs of children, create healthy situations for the development of children’s inborn inclinations. Educators are not reoriented enough to the tendencies of nowadays and only one third of them believe in its importance to meet the natural needs of a child. In most cases parents and educators indicated the same factors which might influence empowering of parents and educators for the education cooperation which would develop into to partnership, but the importance of the factors was often different.
Preliminary work about the basis data for monitoring youth soccer team planning training

The youth soccer is always important especially for the assessment and the data of development of skills. The monitoring of them it could be important for the trainer to reorganize the planning of training and for the adaptation to individual athlete Aim of the study is to recruit the quantitative data about the anthropometric and performance aspects for reutilize to rearrangement of training planning. Method is experimental and has to carry out the usual parameters for monitoring the trainings. Anthropometric data are weight, height, BMI and performance data are Vo2max (Cooper) speed triangle test (three corner run) and speed test with (dribbling) on a sample are 13 athletes of 13 years old that play championship under 14 . BMI Data shows 6 weight, 4 in overweight risk and 3 in overweight. Cooper test data shows 2 above- average, 5 average, 5 below average and 1 poor. Mean speed triangle test 32.38 seconds, mean dibbling test 25.39 seconds. The results have to be useful for tool method of training.
Clinical Efficacy and Adverse Effects of Antibiotics Used to Treat Mycobacterium abscessus Pulmonary Disease

Treatment of Mycobacterium abscessus pulmonary infection requires long-term administration of multiple antibiotics. Little is known, however, about the impact of each antibiotic on treatment outcomes. A retrospective analysis was conducted to evaluate the efficacy and adverse effects of antibiotics administered in 244 cases of M. abscessus pulmonary disease. Only 110 (45.1%) patients met the criteria for treatment success. Treatment with amikacin (AOR, 3.275; 95% CI, 1.221 - 8.788), imipenem (AOR, 2.078; 95% CI, 1.151 - 3.753), linezolid (AOR, 2.231; 95% CI, 1.078 - 4.616) and tigecycline (AOR, 2.040; 95% CI, 1.079 - 3.857) was successful. The incidence of adverse effects was high (192/244, 78.7%). Severe adverse effects were primarily: ototoxicity (14/60, 23.3%) caused by amikacin; gastrointestinal (14/60, 23.3%) caused by tigecycline; and myelosuppression (5/60, 8.3%) caused by linezolid. In conclusion, the rate of success in treating M. abscessus pulmonary disease is still unsatisfactory; the administration of amikacin, imipenem, linezolid and tigecycline correlated with increased treatment success. Adverse side effects are common due to the long-term and combined antibiotic therapy. Ototoxicity, gastrointestinal and myelosuppression are the most severe.
Functional and Neural Signatures of Body-ownership

As agents, we act upon the world with our body, and we experience ourselves, and the world through the same body. This fact implies that the sense of self is crucially dependent on motor-efferent and sensory-afferent signals. The exact nature of sensory-motor interactions that generate a sense of self is still unknown. This research aims to empirically identify the basic neuro-cognitive principles governing an embodied sense of self.
Countries’ Biomedical Publications and Attraction Scores. A PubMed-based assessment

Studying publication volumes at the country level is key to understanding and improving a country’s research system. PubMed is a public search engine of publications in all life sciences areas. Here, we show how this search engine can be used to assess the outputs of life science-related research by country. We have measured the numbers of publications during different time periods based on the country of affiliation of the first authors. Moreover, we have designed scores, which we have named Attraction Scores, to appraise the relative focus either toward particular types of studies, such as clinical trials or reviews, or toward specific research areas, such as public health and pharmacogenomics, or toward specific topics, for instance embryonic stem cells; we have also investigated a possible use of these Attraction Scores in connection with regulatory policies. We have weighed the statistics against general indicators such as country populations and gross domestic products (GDP). During the 5-year period 2008-2012, the United States was the country with the highest number of publications and Denmark the one with the highest number of publications per capita. Among the 40 countries with the highest GDPs, Israel had the highest publications-to-GDP ratio. Among the 20 countries with the most publications, Japan had the highest Attraction Score for induced pluripotent stem (iPS) cells and Italy the highest proportion of review publications. More than 50% of publications in English were from countries in which English is not the primary language. We show an assorted and extensive collection of rankings and charts that will inform scholars and policymakers in studying and improving the research systems both at the national and international level.
Limited loan rate differentiation, guanxi, loan size and loan maturity in the Chinese bank credit market

Abstract Since 2004, China has partially liberalized loan rate setting by the banks, but loan rates remain stubbornly within narrow bounds. We argue that competition in the loan market is signalled through the variation of loan deal terms and loan maturity rather than loan rates. We examine the determinants of loan deal conditions in terms of size and maturity. This paper focuses on the role of single firm-bank relationships in determining loan deal conditions as evidence of guanxi in Chinese banking market. Commercial loan deal terms of listed companies are matched to provider banks over the period 1999–2012 and sub-sample estimation for the pre-2004 and post-2004 periods confirm a change in the bank-firm-loan relationship. We find that single firm-bank relationships are associated with larger loan size and longer loan maturity in the pre-liberalization period but that this relationship has weakened in the liberalization period.
Prognostic significance and biological function of Lamina-associated polypeptide 2 in non-small-cell lung cancer

Purpose: Lamina-associated polypeptide 2 (LAP2; encoded by TMPO), is a nuclear protein that may affect chromatin regulation and gene expression through dynamically binding to nuclear lamin. TMPO (LAP2) plays dual roles of either suppressing or promoting proliferation of cells, depending on the status of the cell. It has been reported that TMPO is up-regulated in various cancer types. However, its function in lung cancer has not been studied yet. Materials and methods: A series of clinical microarray datasets for lung cancer were investigated to demonstrate the expression of TMPO. The transcription of TMPO gene in human lung cancer was analyzed using Oncomine platform (www.oncomine.org) according to the standardized procedures described previously. Four separate datasets (Hou Lung, Okayama Lung, Beer Lung, and Garber Lung) were analyzed. Results: Here, we show that TMPO is over-expressed in lung cancer tissues, and that a high level of TMPO indicates a poor prognosis in lung cancer patients. Knockdown of TMPO in lung cancer cells inhibits cell proliferation and induces apoptosis. Also, down-regulation of TMPO leads to an impaired metastatic ability of tumor cells. A nude mice tumor model show that knockdown of TMPO suppresses tumor formation in vivo. Conclusion: Collectively, this study suggests TMPO as an oncogene and a novel prognostic gene in lung cancer.
Prevention of Pancreatic β-Cell Failure in Type 2 Diabetes. By Targeting a Mitochondrial Voltage Gated Channel 1 and a Novel class of GPCRs.

It has been long known that hyperglycaemia-induced β-cell dysfunction precipitates type 2 diabetes (T2D) in insulin-resistant obesity, although the underlying mechanisms are still poorly defined. The few frequently used antidiabetic drugs on the market have still not satisfactorily demonstrated any long-lasting improvements of β-cell function and prevention of the disease. Islets synthesise and secrete numerous peptides, many of which having important impact on the regulation of metabolism, in particular blood glucose control. In paper I, we quantified mRNAs encoding all peptide ligands of islet G protein-coupled receptors (GPCRs) in isolated human and mouse islets. The study will allow accurate translation of mouse islet functional studies relevant for human physiology, which may pave the way to novel treatment of diabetes. In paper II, we show that ADGRG1 (GPR56) is the most abundant GPCR transcript in both human and mouse islets, and its expression in human islets strongly correlate with genes important for β-cell function. ADGRG1 was reduced in islets of T2D donors, in db/db mouse islets, and in isolated human non-diabetic islets exposed to chronic hyperglycaemia (high glucose concentration in vitro). ADGRG1 activation increased cAMP generation and exerted ant-apoptotic effects. In paper III, we show that long-lasting exposure to high glucose (glucotoxicity) impairs ATP production in β-cells, due to overexpression and coll of the mitochondrial membrane protein VDAC1 to the cell surface. This causes ATP loss, whose attenuation with VDAC1 inhibitors restores β-cell function. Daily injections of a VDAC1 inhibitor prevent the onset of hyperglycaemia in db/db mice. Thus, β-cell function is preserved by targeting the novel diabetes executer protein VDAC1.In paper IV, we show that Adgrg1/GPR56 knock-down (KD) in mouse islets increases the activity of P70S6K, JNK, AKT, NFkb, STAT3 and STAT5. Similar to the hyperglycaemia-induced β-cell dysfunction, the Adgrg1-KD induced β-cell dysfunction seems to be associated with translocation of mitochondrial Vdac1 to the cell membrane resulting in an increased loss of cellular ATP.In paper V, we studied the role of GPR142, expressed in both mouse and human islets. Gpr142 activation by specific agonists increases the generation of cAMP in mouse islets and long-term exposure to high glucose also reduces the expression of Gpr142. Gpr142-KD was associated with increase in Vdac1 expression in mouse islets and INS-1 cells.Taken together the information presented in the current thesis identified the involvement of the novel diabetes executer protein VDAC1 in β-cell dysfunction and suggests VDAC1 as a new target for the prevention of T2D. Keeping the heterogeneity of T2D in mind, additional opportunities i.e. targeting two newly deorphanized GPCRs i.e. ADGRG1 (GPR56) and GPR142 has also been highlighted as novel therapies for the prevention of human T2D. (Less)
Kepuasan Mahasiswa Telkom University Dalam Pencarian Informasi Pada Situs Igracias.telkomunviersity.ac.id Sebagai Media Komunikasi Dan Informasi

ABSTRAK Perpaduan antara teknologi informasi dan teknologi komunikasi dengan tujuan untuk mempermudah proses komunikasi saat ini berkembang dengan pesat, dari perpaduan tersebut muncul istilah Teknologi Informasi dan Komunikasi (TIK) yang dalam penerapannya sangat tergantung kepada ketersediaan koneksi internet. Masyarakat menggunkan teknologi atau media ini didasari oleh motif harapan sebelum menggunakan media dan kesenjangan kepuasan setelah menggunakan media tersebut. Metode penelitian yang digunakan dalam penelitian ini adalah survei deskriptif, dengan pendekatan kuantitatif. Objek yang diteliti dalam penelitian ini adalah igracias.telkomuniversity. ac.id dengan subjek penelitian mahasiswa tingkat I Universitas Telkom 2017. Hasil dari penelitian ini terjadi kesenjangan kepuasan yang dihitung dari skor rata-rata Gratification Sought (GS) dan Gratification Obtained (GO). Skor dari motif informasi didapatkan 3,0540>3,0173 sehingga terjadi kesenjangan yang tidak memuaskan (GS>GO), sedangkan skor dari motif identitas pribadi didapatkan 3,3751>3,3584 sehingga terjadi kesenjangan yang tidak memuaskan (GS>GO), dan skor dari motif integrasi dan interaksi sosial didapatkan 2,8173 3,0173 so that was an unsatisfactory gap (GS> GO), while the score of personal identity motive was 3.3751> 3.3584 that caused an unsatisfactory gap (GS> GO), and the score of the ISSN : 2355-9357 e-Proceeding of Management : Vol.5, No.3 Dsember 2018 | Page 4067 motives of integration and social interaction was obtained 2,8173 <2,8496 that caused a satisfactory gap (GS <GO). Therefore, it could be concluded from these scores that the utilization of igracias.telkomuniversity. ac.id-site had a gap of satisfaction where the media couldn’t satisfy the users, as in the motive information and personal identity. Then where the media could satisfy the users as in the motives of integrity and social interaction. Keywords : Information, Information and Communication Technology, Internet, Motif, Satisfaction, Gap
Alternative mRNA polyadenylation in eukaryotes: an effective regulator of gene expression

Alternative RNA processing mechanisms, including alternative splicing and alternative polyadenylation, are increasingly recognized as important regulators of gene expression. This article will focus on what has recently been described about alternative polyadenylation in development, differentiation, and disease in higher eukaryotes. We will also describe how the evolving global methodologies for examining the cellular transcriptome, both experimental and bioinformatic, are revealing new details about the complex nature of alternative 3′ end formation as well as interactions with other RNA‐mediated and RNA processing mechanisms. WIREs RNA 2011 2 22–31 DOI: 10.1002/wrna.47
Why Medical Students Choose to Use or Not to Use a Web-Based Electrocardiogram Learning Resource: Mixed Methods Study

Background Electrocardiogram (ECG) interpretation is a core competence and can make a significant difference to patient outcomes. However, ECG interpretation is a complex skill to learn, and research has showed that students often lack enough competence. Web-based learning has been shown to be effective. However, little is known regarding why and how students use Web-based learning when offered in a blended learning situation. Objective The aim of this paper was to study students’ use of Web-based ECG learning resources which has not previously been studied in relation to study strategies. Methods A qualitative explanatory design using mixed methods was adopted to explore how medical students reason around their choice to use or not to use a Web-based ECG learning resource. Overall, 15 of 33 undergraduate medical students attending a course in clinical medicine were interviewed. Data on usage of the resource were obtained via the learning management system for all students. At the final examination, all the students answered a questionnaire on study strategies and questions about internet access and estimated their own skills in ECG interpretation. Furthermore, study strategies and use patterns were correlated with results from an ECG Objective Structured Clinical Examination (OSCE) and a written course examination. Results In total, 2 themes were central in the students’ reasoning about usage of Web-based ECG: assessment of learning needs and planning according to learning goals. Reasons for using the Web resource were to train in skills, regarding it as a valuable complement to books and lectures. The main reasons for not using the resource were believing they already had good enough skills and a lack of awareness of its availability. Usage data showed that 21 students (63%) used the Web resource. Of these, 11 were minimal users and 10 were major users based on usage activity. Large variations were found in the time spent in different functional parts of the resource. No differences were found between users and nonusers regarding the OSCE score, final examination score, self-estimate of knowledge, or favoring self-regulated learning. Conclusions To use or not to use a Web-based ECG learning resource is largely based on self-regulated learning aspects. Decisions to use such a resource are based on multifactorial aspects such as experiences during clinical rotations, former study experiences, and perceived learning needs. The students’ own judgment of whether there was a need for a Web-based resource to achieve the learning goals and to pass the examination was crucial for their decisions to use it or not. An increased understanding of students’ regulation of learning and awareness of variations in their ECG learning needs can contribute to the improvement of course design for blended learning of ECG contexts for medical students.
ESTIMATION SOME GENETIC PARAMETERS, COMBINING ABILITY AND HETEROSIS IN PEA (Pisum sativum) USING HALF DIALLEL CROSS.

Experiment of half diallel cross among six pea cultivars was conducted during may 2013. The varietal triats for F1 cross and parents with control were carried out during spring 2015 at the field college of agriculture, university. Duhok using Randomize Complete block Design with three replication. The results were revealed that the general combining ability, and specific combining ability showed significant variance for all traits except days to 50% flowing, No. of plant -1 and 50-grain weight. Also, heritability in broad sensc exhibited high value of whole studied traits except days to 50% flowering, whereas the heritability in narrow sesen gave high value for dray weight plants and 50-grain weight, while chlorophyll exhibited moderate value and other traits gave low value of heritability.
Music Perception in Acquired Prosopagnosia: An Anterior Temporal Syndrome for Faces, Voices and Music

Background Acquired prosopagnosia is often associated with other deficits, such as dyschromatopsia and topographagnosia, from damage to adjacent perceptual networks. A recent study showed that some subjects with developmental prosopagnosia also have congenital amusia, but problems with music perception have not been described in the acquired variant. Objective Our goal was to determine if music perception was also impaired in subjects with acquired prosopagnosia, and if so, its anatomic correlate. Methods We studied eight subjects with acquired prosopagnosia, all of whom had extensive neuropsychological and neuroimaging testing. They performed a battery of tests evaluating pitch and rhythm processing, including the Montréal Battery for the Evaluation of Amusia. Results Three of eight subjects with acquired prosopagnosia had impaired musical pitch perception while rhythm perception was spared. Two of the three also showed reduced musical memory. These three reported alterations in their emotional experience of music: one reported music anhedonia and aversion, while the remaining two had changes consistent with musicophilia. The lesions of these three subjects affected the right or bilateral temporal poles as well as the right amygdala and insula. None of the three prosopagnosic subjects with lesions limited to the inferior occipitotemporal cortex had impaired pitch perception or musical memory, or reported changes in music appreciation. Conclusion Together with the results of our previous studies of voice recognition, these findings indicate an anterior temporal agnosia syndrome that can include the amnestic variant of prosopagnosia, phonagnosia, and various alterations in music perception, including acquired amusia, reduced musical memory, and altered emotional responses to music.
Mapping service user needs to inform a supervised injecting room location in Cork, Ireland.

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