Miracle-dz/UniFAR-FTUs huggingface dataset:
Identification and Quantization of Core Capabilities in Third Party Logistics Based on Principal Component Analysis

With the rapid economic development, the logistics industry plays an increasing important role in China. But China's logistics enterprises lack of apparent core competitiveness. Compared with some advanced countries. through identifying and quantifying competitive factors, logistics enterprises can understand their core capability, and thus can provide higher level customer services. The study takes competitive factors of logistics enterprises as targets, identifying and quantifying the key competitive factors of third party logistics in Zhejiang of China based on Principal Component Analysis (PCA). Moreover, the study put forward focal competitive points and developing methods of third party logistics in different stages, and these findings will be useful to the development of third party logistics. The results may be have some reference for some logistics enterprises.
Guarding against Threatening HIV Prevention Messages: An Information-Processing Model

Previous research has suggested that fear-provoking HIV prevention messages can lead to defensive coping strategies among sexually active students who encounter such messages. An information-processing model of defensive responses is proposed that identifies and operationally defines four mediating processes—attention avoidance, blunting, suppression, and counterargumentation—that may lead to the rejection or denial of threatening health messages. Attention avoidance occurs when people indiscriminately avoid all messages; blunting is the use of distraction to avoid only threatening information in the message. Suppression occurs when people try to stop thinking about the information and avoid forming inferences about its self-relevance; counterargumentation is the biased assessment that follows comprehension and arises along with self-relevant elaboration. Situational influences on people’s choice of defensive coping strategy are considered, and implications for researchers and practitioners are discussed.
Wearable textile antennas' efficiency characterization using a reverberation chamber

Characterization of efficiency is an important consideration to ensure the proper operation of an all-textile wearable antenna. In this work, a small, novel textile antenna is designed based on a planar inverted-F structure (PIFA). The structure incorporates an edge-feeding plate, symmetrical design, and well-placed slot, in order to ease fabrication. A thin conductive textile, Pure Copper Polyester Taffeta Fabric (PCPTF), and fleece is used to fabricate the structure. The efficiency is then verified and measured using a commercial reverberation chamber. Observed results indicate excellent agreements between simulations and measurements.
Pre- and in-hospital delay in treatment and in-hospital mortality after acute myocardial infarction.

PURPOSE 1) To identify the time taken from symptom onset to the arrival at the hospital (pre-hospital delay time) and time taken from the arrival at the hospital to the initiation of the major treatment (in-hospital delay time) 2) to examine whether rapid treatment results in lower mortality. 3) to examine whether the pre- and in-hospital delay time can independently predict in-hospital mortality. METHODS A retrospective study with 586 consecutive AMI patients was conducted. RESULTS Pre-hospital delay time was 5.25 (SD=10.36), and in-hospital delay time was 1.10 (SD=1.00) hours for the thrombolytic therapy and 50.24 (SD=121.18) hours for the percutaneous transluminal coronary angioplasty(PTCA). In-hospital mortality was the highest when the patients were treated between 4 to 48 hours after symptom onset using PTCA (p=.02), and when treated between 30 minutes and one hour after hospital arrival using thrombolytics (p=.01). Using a hierarchical logistic regression model, the pre- and in-hospital delay times did not predict the in-hospital mortality. CONCLUSION Pre- and in-hospital delay times need to be decreased to meet the desirable therapeutic time window. Thrombolytics should be given within 30 minutes after arrival at the hospital, and PTCA should be initiated within 4 hours after symptom onset to minimize in-hospital mortality of AMI patients.
A Regulatory Hydrophobic Area in the Flexible Joint Region of Plasminogen Activator Inhibitor-1, Defined with Fluorescent Activity-neutralizing Ligands

We have characterized the neutralization of the inhibitory activity of the serpin plasminogen activator inhibitor-1 (PAI-1) by a number of structurally distinct organochemicals, including compounds with environment-sensitive spectroscopic properties. In contrast to latent and reactive center-cleaved PAI-1 and PAI-1 in complex with urokinase-type plasminogen activator (uPA), active PAI-1 strongly increased the fluorescence of the PAI-1-neutralizing compounds 1-anilinonaphthalene-8-sulfonic acid and 4,4′-dianilino-1,1′-bisnaphthyl-5,5′-disulfonic acid. The fluorescence increase could be competed by all tested nonfluorescent neutralizers, indicating that all neutralizers bind to a common hydrophobic area preferentially accessible in active PAI-1. Activity neutralization proceeded through two consecutive steps as follows: first step is conversion to forms displaying substrate behavior toward uPA, and second step is to forms inert to uPA. With some neutralizers, the second step was associated with PAI-1 polymerization. Vitronectin reduced the susceptibility to the neutralizers. Changes in sensitivity to activity neutralization by point mutations were compatible with the various neutralizers having overlapping, but not identical, binding sites in the region around α-helices D and E and β-strand 1A, known to act as a flexible joint when β-sheet A opens and the reactive center loop inserts as β-strand 4A during reaction with target proteinases. The defined binding area may be a target for development of compounds for neutralizing PAI-1 in cancer and cardiovascular diseases.
Expression of Serum Sialic Acid, Early Antigen-IgA, and Viral Capsid Antigen-IgA in Nasopharynx Cancer Patients: The Diagnostic Implication of Combined Assays

Background Ebstein-Barr virus (EBV) plays a critical role in nasopharynx cancer, which can be effectively monitored by serum levels of early antigen antibody (EA-IgA) and viral capsid antigen antibody (VCA-IgA). This study explored the diagnostic value of combined assays of sialic acid (SA), EA-IgA, and VCA-IgA via the expressional assay. Material/Methods A total of 42 nasopharynx cancer patients and 42 benign rhinitis and healthy controls were recruited in this study. Serum EA-IgA and VCA-IgA were tested by enzyme-linked immunosorbent assay (ELISA) and enzymatic assay of serum SA. Specificity and sensitivity of those 3 assays were compared. The diagnostic value of each parameter was evaluated by ROC curves. Results All 3 indexes (SA, EA-IgA and VCA-IgA) showed elevated serum levels in nasopharynx cancer patients when compared to those with rhinitis, who had higher levels than healthy individuals. Concentrations of these factors were also positively correlated with the TNM staging of cancer. The sensitivity and specificity were 30.95% and 83.33% (in SA), 57.14% and 95.24% (in EA-IgA), and 76.19% and 92.86% (in VCA-IgA), respectively. VCA-IgA had the highest sensitivity among all 3 indexes. The combined assay increased the diagnostic sensitivity to 92.86% without compromising specificity. Conclusions SA, EA-IgA, and VCA-IgA levels were significantly elevated in nasopharynx patients’ serum. The combined assay may have clinical value in diagnosis and monitoring.
Is smoking related to body image satisfaction, stress, and self-esteem in young adults?

OBJECTIVES To examine the association of smoking and gender with body image satisfaction, perceived stress, and self-esteem in young adults. METHODS Respondents completed a survey consisting of Perceived Stress Scale, Body-Areas Satisfaction Scale, Rosenberg Self-Esteem Scale, and the Positive and Negative Affect Schedule. Current smokers (n = 483) and never smokers (n = 973) are included. RESULTS Smoking and female gender were independently associated with higher perceived stress (P < 0.001). Female gender was associated with lower body image satisfaction and lower self-esteem (P < 0.001). Current smoking was associated with lower self-esteem (P = 0.007). CONCLUSION Smoking treatment should include stress management and self-esteem and body image improvement.
Identification of FAZF as a novel BMP2‐induced transcription factor during osteoblastic differentiation

Bone morphogenetic protein 2 (BMP2) is a key factor in the regulation of osteoblastic differentiation; however, its downstream mediators are not fully understood. Previously, we identified and characterized transcription factor promyelocytic leukemia zinc finger protein (PLZF), composed of an N‐terminal BTB/POZ and C‐terminal zinc finger motifs, as an upstream factor of CBFA1 (Runx2/core‐binding factor 1). PLZF was induced in an osteoblastic differentiation medium, but was not induced by BMP2. Here, we report the identification of transcription factor fanconi anemia zinc finger protein (FAZF), which is closely related to PLZF. FAZF was induced by BMP2 in human mesenchymal stem cells (hMSCs). In addition to the full‐length FAZF, we also identified alternatively spliced mRNAs in which the C‐terminal zinc finger motifs were deleted (designated BTB/POZ‐only FAZF). Both the full‐length and BTB/POZ‐only FAZF mRNAs were equally expressed in BMP2‐treated hMSCs. The full‐length FAZF was exclusively detected in the nucleus, whereas the BTB/POZ‐only FAZF protein was localized in the cytoplasm of the transfected cells. The full‐length FAZF, but not the BTB/POZ‐only FAZF, increased the expression of osteoblastic differentiation markers, including CBFA1, collagen 1A1, osteocalcin, and alkaline phosphatase in C2C12 cells. In conclusion, both FAZF and PLZF differentially participate in the regulation of osteoblastic differentiation via the BMP2 and CBFA1 signaling pathways, respectively. J. Cell. Biochem. 101: 147–154, 2007. © 2006 Wiley‐Liss, Inc.
Complement Component C3 Binds to Activated Normal Platelets without Preceding Proteolytic Activation and Promotes Binding to Complement Receptor 1

It has been reported that complement is activated on the surface of activated platelets, despite the presence of multiple regulators of complement activation. To reinvestigate the mechanisms by which activated platelets bind to complement components, the presence of complement proteins on the surfaces of nonactivated and thrombin receptor-activating peptide-activated platelets was analyzed by flow cytometry and Western blot analyses. C1q, C4, C3, and C9 were found to bind to thrombin receptor-activating peptide-activated platelets in lepirudin-anticoagulated platelet-rich plasma (PRP) and whole blood. However, inhibiting complement activation at the C1q or C3 level did not block the binding of C3 to activated platelets. Diluting PRP and chelating divalent cations also had no effect, further indicating that the deposition of complement components was independent of complement activation. Furthermore, washed, activated platelets bound added C1q and C3 to the same extent as platelets in PRP. The use of mAbs against different forms of C3 demonstrated that the bound C3 consisted of C3(H2O). Furthermore, exogenously added soluble complement receptor 1 was shown to bind to this form of platelet-bound C3. These observations indicate that there is no complement activation on the surface of platelets under physiological conditions. This situation is in direct contrast to a number of pathological conditions in which regulators of complement activation are lacking and thrombocytopenia and thrombotic disease are the ultimate result. However, the generation of C3(H2O) represents nonproteolytic activation of C3 and after factor I cleavage may act as a ligand for receptor binding.
Axial and reformatted four-chamber right ventricle-to-left ventricle diameter ratios on pulmonary CT angiography as predictors of death after acute pulmonary embolism.

OBJECTIVE The purpose of this article is to retrospectively compare right ventricular-to-left ventricular (RV/LV) diameter ratios measured on the standard axial view versus the reformatted four-chamber view as predictors of mortality after acute pulmonary embolism (PE). MATERIALS AND METHODS Six hundred seventy-four consecutive patients (mean age, 58 years; 372 women) with a diagnosis of acute PE on pulmonary CT angiography were considered. The axial and reformatted four-chamber RV/LV diameter ratios were compared as predictors of 30-day all-cause and PE-related mortality. RESULTS Ninety-seven patients (14%) died within 30 days; 39 deaths were PE related. There was no significant difference in the univariate hazard ratios (HRs) of axial and four-chamber RV/LV diameter ratios greater than 0.9 for both all-cause (HR, 2.13 [95% CI, 1.29-3.51] vs HR, 1.95 [95% CI, 1.22-3.14]; p = 0.74) and PE-related (HR, 19.6 [95% CI, 2.70-143] vs HR, 21.8 [95% CI, 2.99-158]; p = 1.0) mortality. Axial and four-chamber multivariate HRs accounting for potential confounders such as age and cancer were also similar for all-cause (HR, 1.79 [95% CI, 1.07-2.99] vs HR, 1.54 [95% CI, 0.95-2.49]; p = 0.62) and PE-related (HR, 16.3 [95% CI, 2.22-119] vs HR, 17.7 [95% CI, 2.43-130]; p = 1.0) mortality. There was no significant difference in sensitivity, specificity, negative predictive value, or positive predictive value. Axial and four-chamber measurements were well correlated (correlation coefficient, 0.857), and there was no significant difference in overall accuracy for predicting all-cause (area under the curve [AUC], 0.582 vs 0.577; p = 0.72) and PE-related (AUC, 0.743 vs 0.744; p = 1.0) mortality. CONCLUSION The axial RV/LV diameter ratio is no less accurate than the reformatted four-chamber RV/LV diameter ratio for predicting 30-day mortality after PE.
Spectral formation in accreting X-ray pulsars: bimodal variation of the cyclotron energy with luminosity

Context. Accretion-powered X-ray pulsars exhibit significant variability of the cyclotron resonance scattering feature (CRSF) centroid energy on pulse-to-pulse timescales, and also on much longer timescales. Two types of spectral variability are observed. For sources in group 1, the CRSF energy is negatively correlated with the variable source luminosity, and for sources in group 2, the opposite behavior is observed. The physical basis for this bimodal behavior is currently not well understood. Aims. We explore the hypothesis that the accretion dynamics in the group 1 sources is dominated by radiation pressure near the stellar surface, and that Coulomb interactions decelerate the gas to rest in the group 2 sources. Methods. We derive a new expression for the critical luminosity, Lcrit, such that radiation pressure decelerates the matter to rest in sources with X-ray luminosity LX > Lcrit. The formula for Lcrit is based on a simple physical model for the structure of the accretion column in luminous X-ray pulsars that takes into account radiative deceleration, the energy dependence of the cyclotron cross section, the thermodynamics of the accreting gas, the dipole structure of the pulsar magnetosphere, and the diffusive escape of radiation through the column walls. We show that for typical neutron star parameters, Lcrit = 1.5 × 10 37 B 16/15 12 erg s −1 ,w hereB12 is the surface magnetic field strength in units of 10 12 G. Results. The formula for the critical luminosity is evaluated for five sources, using the maximum value of the CRSF centroid energy to estimate the surface magnetic field strength B12. The results confirm that the group 1 sources are supercritical (LX > Lcrit )a nd the group 2 sources are subcritical (LX < Lcrit), although the situation is less clear for those highly variable sources that cross over the line LX = Lcrit. We also explain the variation of the CRSF energy with luminosity as a consequence of the variation of the characteristic emission height. The sign of this dependence is opposite in the supercritical and subcritical cases, hence creating the observed bimodal behavior. Conclusions. We have developed a new model for the critical luminosity in accretion-powered X-ray pulsars that explains the bimodal dependence of the CRSF centroid energy on the X-ray luminosity LX. Our model provides a physical basis for the observed variation of the CRSF energy as a function of LX for both the group 1 (supercritical) and the group 2 (subcritical) sources as a result of the variation of the emission height in the column.
Visceral protein response to enteral versus parenteral nutrition and sepsis in patients with trauma.

BACKGROUND Sepsis and the route of nutrient administration are clearly related to visceral protein levels; however, the mechanisms and amount of influence are not completely defined. METHODS Constitutive and acute-phase protein levels were measured on days 1, 4, 7, and 10 in 68 severely injured patients with abdominal trauma indexes of 15 or more randomized to enteral or parenteral feeding. Groups were matched for age, abdominal trauma index, injury severity score, and length of stay. RESULTS Significantly higher levels of constitutive proteins and lower levels of acute-phase proteins were found in patients randomized to enteral feeding. Although some "hepatic protein reprioritization" appeared to be caused by nutrient route, this appeared only in the less severely injured patients. A more important factor in visceral protein levels is a reduction in septic morbidity associated with enteral feeding. CONCLUSIONS Enteral feeding produces greater increase in constitutive proteins and greater decreases in acute-phase proteins after severe trauma primarily caused by reduced septic morbidity with enteral feeding.
Extension block technique for mallet fractures: a comparison of one and two dorsal pins

The aim of this study was to compare the clinical and radiological outcomes of one or two dorsal pins for extension blocking of mallet fractures. We treated 36 mallet fractures with the extension block technique. A single pin was used in 19 fractures (Group 1) and two pins in 17 fractures (Group 2). The mean age was 33.6 years and the mean follow-up time was 12.2 months. All patients were assessed by the Crawford outcome score. Extensor lag and other complications were noted. All fractures united with a mean time of 6.0 weeks (4–9) in Group 1, and 6.1 weeks (4–7) in Group 2. We obtained 74% and 71% excellent and good outcome scores in Group 1 and in Group 2, respectively. The final extension lag was 6° in Group 1, and 7° in Group 2. No difference was found between the two groups in terms of clinical outcomes, radiological values and complications. Level 3 non-randomized controlled study.
Low-Level Viremia and Intracellular Expression of Hepatitis B Surface Antigen (HBsAg) in HBsAg Carriers with Concurrent Hepatitis C Virus Infection

ABSTRACT Assays of hepatitis B virus (HBV) replication and antigen expression in HBV surface antigen (HBsAg) carriers with concurrent hepatitis C or D virus (HCV or HDV) infection revealed that HCV and HDV can suppress HBV replication but that HCV also substantially suppresses HBV surface protein expression. HBsAg carriers with concurrent HCV infection thus have low-level viremia and intracellular HBsAg.
Policing Immigration

Today, local police are being integrated into federal immigration enforcement on a scale never seen before in American history. This transformation of immigration law is not the result of the high-profile efforts by Arizona and a few other states to regulate migrants. Instead, it is the product of a largely overlooked federal program known as "Secure Communities. " Launched three years ago, the program's goal is simple: to check the immigration status of every single person arrested by local police anywhere in the country. Secure Communities represents the future of immigration enforcement. It dramatically lowers the information cost of identifying immigration violators, accelerates the ongoing convergence of the immigration and criminal bureaucracies in the United States, and reshapes the structure of immigration federalism. Despite its significance, however, little is known about the program. This Article, part of a larger project providing the first large-scale empirical evaluation of Secure Communities, uses the program's rollout to explore a pervasive feature of criminal and administrative law that rarely lends itself to empirical examination-the role of discretion in policing. The breadth of discretion
Oral and Dental Aspects of Chronic Renal Failure

The present article reviews, in detail, the current knowledge of the oral and dental aspects of chronic renal failure (CRF). Worldwide, increasing numbers of persons have CRF; thus, oral health care staffs are increasingly likely to provide care for patients with such disease. Chronic renal failure can give rise to a wide spectrum of oral manifestations, affecting the hard or soft tissues of the mouth. The majority of affected individuals have disease that does not complicate oral health care; nevertheless, the dental management of such individuals does require that the clinician understand the multiple systems that can be affected. The clinician should also consider the adverse side-effects of drug therapy and appropriate prescribing, in view of compromised renal clearance.
Multiplex sequencing for EZH2, CD79B, and MYD88 mutations using archival cytospin preparations from B‐cell non‐Hodgkin lymphoma aspirates previously tested for MYC rearrangement and IGH/BCL2 translocation

Gene rearrangements and specific translocations define some B‐cell non‐Hodgkin lymphoma (NHL) subtypes. Genome‐wide mutational studies have revealed recurrent point mutations with prognostic implications. The goals of this study were to evaluate the feasibility of applying a multiplex mutation assay to archival cytospin preparations (CPs) and to investigate the rate of EZH2, CD79B, and MYD88 mutations in B‐cell NHL samples previously tested for MYC rearrangement and/or IGH/BCL‐2 translocation.
Determinants of knowledge sharing in a public sector organization

Purpose – The purpose of this paper is to investigate the factors that affect knowledge sharing in a public sector organization.Design/methodology/approach – The paper is based on quantitative research. The data were gathered through questionnaires and analyzed using multiple regression.Findings – Community‐related considerations, normative considerations and personal benefits were three motivators found to have a unique contribution to the variance in knowledge sharing. The following enablers had a significant main effect on knowledge sharing: social interaction, rewards, and organizational support. Two barriers, degree of courage and degree of empathy, which measured organizational climate, were found to have a significant main effect on knowledge sharing. The interaction of normative consideration with social interaction, personal benefit with organizational support, and normative considerations with degree of courage, had a moderating effect on the relationship between motivating factors and knowledge.
Why should we screen for perinatal depression? Ten reasons to do it REVIEW

In this paper we review some of the best available evidence to argue that screening for perinatal depression should be systematically conducted since pregnancy. Our view is organized in ten topics: (1) perinatal depression high prevalence; (2) its potential negative consequences, including maternal, conjugal, foetal, infantile, and child effects; (3) its under-detection and treatment; (4) its stigma; (5) the professionals and women misconceptions related to perinatal depression; (6) the availability of valid and short self-report screening instruments for perinatal depression and (7) their acceptability; (8) the increase in recognition, diagnosis, and treatment rates in comparison with routine practice; (9) the opportunity, given the large number of contacts that women have with health professionals in the perinatal period; and (10) perinatal depression screening potential cost-effectiveness.