Miracle-dz/UniFAR-FTUs huggingface dataset:
Improving Distance Estimation in Object Localisation with Bluetooth Low Energy

—The arrival of Bluetooth Low Energy (BLE) creates opportunities for great innovations. One possible application is object localisation. We present our unique software that can track objects and help ﬁnding their location within a house perimeter. With the help of Bluetooth beacons that can be attached to different items, we can estimate the distance between the mobile device and the object with an accuracy of less than one meter. In this paper, we describe our system and the techniques we use, the experiments we conducted along with the results. In addition, we brieﬂy present some work in progress using an indoor positioning system that helps locating the objects.
Histopathology of non‐scarring alopecia

The lollowitig disett.s. sion loett.ses on llie histopathologic iitiditigs in non-seaiiing lorm.s of alopeeia. Exehided IVom this clisenssion ate Ibrtns ol hair loss resulting IVom dist)rders of the hair shalt, whieh eattse hair fragility atid breakage. Hair shaft disoi ders are tistially diagnosed by examination ol elipped hair shalts, and histopalhologie examination is seldom pursued. Searritig alopeeia resttlts in pertnanent hair loss as fbllieles are destroyed at:id replaced by libroits lissvte. Eoss of hair in noti-searring alopeeia is often reversible, atid usually oeeurs by one of IVnnmeehanistiis. The first is telogen effltivitim, in whieh greater that normal ntttiibeis of hairs are preeipitated into the telogen phase, restrltitig iti excessive shedding of telogen hairs. A classic example is post-partuni telogeti efllrtviutii, oecurritig abcntt three months after ati affeeted woman delivers a haby. The seeotid tnechatiism for hair loss is anagen elTlttvitim (also called anagen delltivinm), eatised by an abrnpt hall in ihe metabolic machinery of actively gixnving anagen hairs. This lestilts in the shedding ol tiumerous abnormal ("dystrophic") anagen hairs. The classic example ol anagen eflluvium is hair loss alter raclialion therapy or chemotherapy. In many cases of tion-scarring alopecia, excessive shedding of both, telogen hairs and anagen hairs occttrs, bhirring the distinction between telogen el'lltivium and anagen ellltivitnn.
Predicting MHC Class II Epitopes Using Separated Constructive Clustering Ensemble

Successful Prediction for MHC Class II epitopes is an essential step in designing Genetic Vaccines(1). MHC Class II epitopes are short peptides with length between 9 and 25 amino acids which are bound by MHC. These epitopes are recognized by T-Cell Receptors and leads to activation of cellular and humoral immune system and, ultimately, to ef- fective destruction of pathogenic organism. Successful prediction of MHC class II epitopes is more difficult than MHC class I epitopes due to open binding groove at both ends in class II molecules, this structure leads to variable length for MHC II epitopes and complicating the task for detecting the core binding 9-mer. Large efforts have been exerted in devel- oping algorithms to predict which peptides will bind to a given MHC class II molecules. In this paper we presented a novel classification algorithm for predicting MHC Class II epitopes using Multiple Instance Learning technique. Separated Con- structive Clustering Ensemble (SCCE) is our new version for Constructive Clustering Ensemble (CCE)(27). This method was used for converting multiple instance learning problem into normal Single Instance Problem. Most of the processing in this method lies mainly in vector preparation step before using classifier; Support Vector Machine (SVM) has been used as a method with proven performance in a wide range of practical applications(38). SCCE integrated many algorithms like Genetic Algorithm, K medoid clustering, Ensemble learning and Support vector machine in an orchestration to predict the MHC II epitopes. SCCE was tested over three benchmark data sets and proved to be very competitive with the state of art regression methods. SCCE achieved these results using only binder and non binder flags; without need for regression data. An implementation of MHCII-SCCE as an online web server for predicting MHC-II Epitopes is freely accessible at http://www.fci. cu.edu. eg:8080/MHCII_Server/MHCII SCCE Server 1.0. htm.
Propagation of intense subpicosecond laser pulses through underdense plasmas.

The propagation of an intense, subpicosecond laser pulse through a substantial length ({ital L}/{lambda}{similar_to}10{sup 3}) of an underdense plasma ({ital n}/{ital n}{sub {ital c}}{similar_to}1%) is studied through experiments and computer simulations. For {ital I}=8{times}10{sup 17} W/cm{sup 2} only 55% of the incident laser light was transmitted through the plasma within the focal cone angle. The decrease in transmission was accompanied by Raman forward scattering as evidenced by the generation of anti-Stokes sidebands and up to 2 MeV electrons. Simulations show that the majority of the reduction in transmission could be due to Raman forward and side scattering.
The Willingness to Intervene Against Suicide Questionnaire

Three studies resulted in the Willingness to Intervene Against Suicide Questionnaire. College students (ns = 172, 253, and 367) completed an online questionnaire based on theory of planned behavior constructs regarding suicide intervention. Exploratory factor analysis produced 10 factors: intervening will affect the suicidal person and the participant; important others recommend seeking help, suggesting the suicidal person see a counselor, and talking to the suicidal person; interpersonal and intervention self-efficacy; and intention to seek outside help, encourage to seek outside help, and recognize a need for action. The Willingness to Intervene Against Suicide Questionnaire assesses college students’ willingness to intervene when someone is suicidal.
Competency-based student self-assessment on a surgery rotation.

BACKGROUND Although self-assessment is an essential component of self-directed adult learning, few data exist regarding the ability of medical students to perform this important task. Therefore, the purpose of this study was to evaluate the ability of medical students to perform self-assessment during a third-year surgery clerkship. METHODS Sixty-eight (34 male, 34 female) third-year medical students assessed their progress at the midpoint of an 8-week surgery clerkship using an 11-item, competency-based evaluation. Students compared perceptions of their performance with a faculty member's assessment using the identical evaluation form. RESULTS Male students tended to overestimate their midclerkship performance compared with faculty formative and summative evaluations (3.31 +/- 0.03 vs 3.23 +/- 0.03 and 3.28 +/- 0.03) although this did not reach statistical significance. Female students significantly underestimated their midclerkship performance compared with faculty formative and summative evaluations (3.06 +/- 0.03 vs 3.40 +/- 0.03 and 3.45 +/- 0.03, P < 0.05 vs faculty evaluations). Preclerkship academic performance (first- and second-year grade point averages and NBME Part 1 scores) was not predictive of student self-assessment. Finally, women statistically outperformed men on the surgery clerkship (86.6% +/- 0.75 vs 83.2% +/- 1.20, P < 0.05 vs male students). CONCLUSIONS Female students tend to underestimate their midclerkship performance compared with male students on a surgery rotation. Despite lower self-assessment, female students actually outperform male students. Women may underreport their capabilities when compared with men as a result of gender differences in socialization. These gender differences in self-assessment may be important to recognize when faculty provide feedback to students.
Zinc Inhibits Doxorubicin-Activated Calcineurin Signal Transduction Pathway in H9c2 Embryonic Rat Cardiac Cells

Elevation of the zinc-binding protein metallothionein (MT) in the heart inhibits doxorubicin (DOX)-induced myocardial apoptosis and heart hypertrophy. Zinc release from MT in response to oxidative stress has been suggested as a mechanism of action of MT protection from DOX toxicity, and calcineurin is involved in the signaling pathways leading to myocardial apoptosis and heart hypertrophy. The present study was undertaken to determine if zinc can modulate the DOX-activated calcineurin signaling pathway. H9c2 cells were treated with 1 μM DOX, and zinc release was monitored by a zinc ion–specific fluorophore, zinquin ethyl ester. Additionally, DOX-activated calcineurin signaling was detected by a calcineurin-dependent nuclear factor of activated T-cell reporter. DOX treatment induced an increase in intracellular labile zinc and activated calcineurin signaling. Pretreatment of H9c2 cells with a zinc-specific, membrane-permeable chelating agent, N,N,N′,N′-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN), inhibited the increase in intracellular labile zinc and increased the DOX-activated calcineurin signaling. Pretreatment of H9c2 cells with exogenously added zinc attenuated the DOX-activated calcineurin signaling in a dose-dependent manner. However, neither TPEN nor addition of exogenous zinc affected DOX-induced cellular hypertrophy or DOX-induced decrease in cell viability. Additionally, inhibition of DOX-induced calcineurin signaling with the calcineurin inhibitors cyclosporine A or tacrolimus (FK506) failed to restrict the DOX-induced decrease in cell viability. These results indicate that zinc suppresses DOX-induced calcineurin signaling in H9c2 cells; however, calcineurin signaling is not involved in the DOX-induced decrease in cell viability in H9c2 cells. (It had been shown previously that calcineurin is also not necessary for DOX-induced H9c2 cell hypertrophy.)
POWERFUL H2 LINE COOLING IN STEPHAN's QUINTET. I. MAPPING THE SIGNIFICANT COOLING PATHWAYS IN GROUP-WIDE SHOCKS

We present results from the mid-infrared spectral mapping of Stephan's Quintet using the Spitzer Space Telescope. A 1000 km s-1 collision (tcol = 5 × 106 yr) has produced a group-wide shock, and for the first time the large-scale distribution of warm molecular hydrogen emission is revealed, as well as its close association with known shock structures. In the main shock region alone we find 5.0 × 108 M☉ of warm H2 spread over ∼480 kpc2 and additionally report the discovery of a second major shock-excited H2 feature, likely a remnant of previous tidal interactions. This brings the total H2 line luminosity of the group in excess of 1042 erg s-1. In the main shock, the H2 line luminosity exceeds, by a factor of 3, the X-ray luminosity from the hot shocked gas, confirming that the H2-cooling pathway dominates over the X-ray. [Si ii]34.82 μm emission, detected at a luminosity of 1/10th of that of the H2, appears to trace the group-wide shock closely, and in addition, we detect weak [Fe ii]25.99 μm emission from the most X-ray luminous part of the shock. Comparison with shock models reveals that this emission is consistent with regions of fast shocks (100 km s-1 < Vs < 300 km s-1) experiencing depletion of iron and silicon onto dust grains. Star formation in the shock (as traced via ionic lines, polycyclic aromatic hydrocarbon and dust emission) appears in the intruder galaxy, but most strikingly at either end of the radio shock. The shock ridge itself shows little star formation, consistent with a model in which the tremendous H2 power is driven by turbulent energy transfer from motions in a post-shocked layer which suppresses star formation. The significance of the molecular hydrogen lines over other measured sources of cooling in fast galaxy-scale shocks may have crucial implications for the cooling of gas in the assembly of the first galaxies.
Three lessons for genetic toxicology from baseball analytics

In many respects the evolution of baseball statistics mirrors advances made in the field of genetic toxicology. From its inception, baseball and statistics have been inextricably linked. Generations of players and fans have used a number of relatively simple measurements to describe team and individual player's current performance, as well as for historical record‐keeping purposes. Over the years, baseball analytics has progressed in several important ways. Early advances were based on deriving more meaningful metrics from simpler forerunners. Now, technological innovations are delivering much deeper insights. Videography, radar, and other advances that include automatic player recognition capabilities provide the means to measure more complex and useful factors. Fielders' reaction times, efficiency of the route taken to reach a batted ball, and pitch‐framing effectiveness come to mind. With the current availability of complex measurements from multiple data streams, multifactorial analyses occurring via machine learning algorithms have become necessary to make sense of the terabytes of data that are now being captured in every Major League Baseball game. Collectively, these advances have transformed baseball statistics from being largely descriptive in nature to serving data‐driven, predictive roles. Whereas genetic toxicology has charted a somewhat parallel course, a case can be made that greater utilization of baseball's mindset and strategies would serve our scientific field well. This paper describes three useful lessons for genetic toxicology, courtesy of the field of baseball analytics: seek objective knowledge; incorporate multiple data streams; and embrace machine learning. Environ. Mol. Mutagen. 58:390–397, 2017. © 2017 Wiley Periodicals, Inc.
Distribution of Schmallenberg virus and seroprevalence in Belgian sheep and goats.

A serological survey to detect Schmallenberg virus (SBV)-specific antibodies by ELISA was organized in the Belgian sheep population to study the seroprevalence at the end of the epidemic. One thousand eighty-two sheep samples which were collected from 83 herds all over Belgium between November 2011 and April 2012 were tested. The overall within-herd seroprevalence and the intraclass correlation coefficient were estimated at 84.31% (95% CI: 84.19-84.43) and 0.34, respectively. The overall between-herd seroprevalence was 98.03% (95% CI: 97.86-98.18). A spatial cluster analysis identified a cluster of six farms with significantly lower within-herd seroprevalence in the south of Belgium compared with the rest of the population (P = 0.04). It was shown that seroprevalence was associated to flock density and that the latter explained the presence of the spatial cluster. Additionally, 142 goat samples from eight different herds were tested for SBV-specific antibodies. The within-herd seroprevalence in goats was estimated at 40.68% (95% CI: 23.57-60.4%). The results of the current study provided evidence that almost every Belgian sheep herd has been in contact with SBV during 2011 and should be taken into consideration as part of comprehensive SBV surveillance and control strategies.
Towards a theory of shopping: a holistic framework

One criticism (Arnould, 2000) of Miller's 1998 book, A Theory of Shopping and the jointly authored Shopping, Place and Identity (Miller et al., 1998) is that the authors fail to incorporate or even acknowledge the body of literature which exists within marketing and consumer research. Thus, as Arnould states, ‘the authors rediscover some of the findings of theoretical marketing literature about shopping venues, shopping and customer–store and service relationships’ (Arnould, 2000, p. 106). This paper attempts to redress the balance by proposing a conceptual framework for shopping which incorporates relevant marketing and consumer research literature and which also draws on the wider literature in the social sciences to set the context for progress towards a theory of shopping. Copyright © 2002 Henry Stewart Publications.
Propofol Dosing Regimens for ICU Sedation Based upon an Integrated Pharmacokinetic– Pharmacodynamic Model

Background The pharmacology of propofol infusions administered for long-term sedation of intensive care unit (ICU) patients has not been fully characterized. The aim of the study was to develop propofol dosing guidelines for ICU sedation based on an integrated pharmacokinetic–pharmacodynamic model of propofol infusions in ICU patients. Methods With Institutional Review Board approval, 30 adult male medical and surgical ICU patients were given target-controlled infusions of propofol for sedation, adjusted to maintain a Ramsay sedation scale score of 2–5. Propofol administration in the first 20 subjects was based on a previously derived pharmacokinetic model for propofol. The last 10 subjects were given propofol based on a pharmacokinetic model derived from the first 20 subjects. Plasma propofol concentrations were measured, together with sedation score. Population pharmacokinetic and pharmacodynamic parameters were estimated by means of nonlinear regression analysis in the first 20 subjects, then prospectively tested in the last 10 subjects. An integrated pharmacokinetic–pharmacodynamic model was used to construct dosing regimens for light and deep sedation with propofol in ICU patients. Results The pharmacokinetics of propofol were described by a three-compartment model with lean body mass and fat body mass as covariates. The pharmacodynamics of propofol were described by a sigmoid model, relating the probability of sedation to plasma propofol concentration. The pharmacodynamic model for propofol predicted light and deep levels of sedation with 73% accuracy. Plasma propofol concentrations corresponding to the probability modes for sedation scores of 2, 3, 4, and 5 were 0.25, 0.6, 1.0, and 2.0 &mgr;g/ml. Predicted emergence times in a typical subject after 24 h, 72 h, 7 days, and 14 days of light sedation (sedation score = 3 → 2) with propofol were 13, 34, 198, and 203 min, respectively. Corresponding emergence times from deep sedation (sedation score = 5 → 2) with propofol were 25, 59, 71, and 74 h. Conclusions Emergence time from sedation with propofol in ICU patients varies with the depth of sedation, the duration of sedation, and the patient’s body habitus. Maintaining a light level of sedation ensures a rapid emergence from sedation with long-term propofol administration.
A Comparison of the Traditional, Swing, and Chicken Wing Arm Movements on Volleyball Blocking in NCAA Division 1 Female Athletes

A Comparison of the Traditional, Swing, and Chicken Wing Arm Swings on Volleyball Blocking in NCAA Division I Female Athletes Taubi J Neves Department of Exercise Sciences Master of Science Blocking is highly correlated with team success. The identification of specific techniques that produce a more successful block would be helpful knowledge for coaches and players. This study compared the traditional, swing, and chicken wing arm swings in combination with the running step footwork pattern in order to determine which arm swing enabled athletes to perform a more effective block. The time it took the athletes to get off the ground and get their hands above (vertically) the net was calculated. The distance the hand reached over the net or hand penetration (displacement between the net and finger in the anterior and vertical planes) was also measured. Lastly, jump height was calculated. High-speed videography was used to capture the blocking movements of thirteen female NCAA Division I athletes. Data were analyzed using a repeated measures ANOVA test, pairwise comparison, and co-variate analysis. The chicken wing block arm swing was quickest in getting the athlete off the ground and getting their hands above the net. The swing block was greatest for hand penetration and jump height. These results can help coaches and players decide which arm swing will benefit them most as a blocking team and as individual blockers.
Correlation properties of MIMO radio channels for indoor scenarios

Multiple input- multiple output (MIMO) systems have the potential to achieve very high capacities, depending on the propagation environment. Capacity increases as signal correlation decreases. We present the measurements of a MIMO system under strong and weak line-of-sight conditions. The system capacity decreases as the separation from the transmitter increases; indeed the transmitter correlation increases as the separation increases. The receiver correlation is lower than the transmitter correlation under both propagation conditions. Also, there lies a benefit in using vertically polarized, vertically separated antennas.
Serous Tubal Intraepithelial Carcinoma Localizes to the Tubal-peritoneal Junction: A Pivotal Clue to the Site of Origin of Extrauterine High-grade Serous Carcinoma (Ovarian Cancer)

Recent data suggest that intraepithelial carcinoma of the fallopian tube [serous tubal intraepithelial carcinoma (STIC)] is the precursor of high-grade extrauterine serous carcinoma. A more specific location for the origin of this lesion is suggested by the recently described junction between the fallopian tubal epithelium and the peritoneum [tubal-peritoneal junction (TPJ)]. Fallopian tubes from 202 patients with advanced-stage high-grade extrauterine serous carcinoma or carcinosarcoma were evaluated histologically as were 124 prophylactic salpingo-oophorectomy specimens. These included 54 patients with BRCA or other high-risk mutation or a family history of BRCA mutation and 70 with a personal or family history of breast carcinoma. STIC was found in 81 of 202 patients with serous carcinoma (40.1%). STIC was present in 73 of 141 (52%) cases in which the fimbriae were present and in 62 of 100 (62%) cases in which the TPJ was present (P not significant). In comparison with these groups, when fimbriae and TPJ were absent, STIC was found in 8 of 61 (13%) cases (P<0.0001). None of the prophylactic specimens contained STIC. The mean size of STIC was 1.7 mm. In 32 cases (39.5%), the lesion was flat and in 49 (60.5%), papillary. The mean size of flat STICs was 0.8 mm as compared with 2.3 mm for papillary STICs (P=0.00005). STIC was identified in the same tissue fragment as the junction in 48 cases. The mean distance of STIC to the junction was 1.8 mm. In 11 cases, STIC was flanked by peritoneal mesothelium on one side and tubal epithelium on the opposite side. In 51 patients, the mean distance of invasive carcinoma from the TPJ was 1.8 mm. This distance was 1.9 mm when STIC was present (37 cases) in comparison with 1.5 mm when STIC was absent (14 cases) (P not significant). In 27 of 42 cases (64%), STIC was contiguous with invasive carcinoma. Lamina propria invasion was present in 71% of cases in which STIC was present as compared with 26% of cases in which STIC was absent (P<0.0001). Myosalpingeal invasion was present in 40% of cases in which STIC was present as compared with 26% of cases in which STIC was absent (P not significant). It is concluded that serous tubal intraepithelial carcinoma occurs at and in the immediate vicinity of the TPJ. In combination with the findings that STICs are present in a majority of cases when the TPJ is present, that flat STICs are smaller than papillary STICs, and that lamina propria invasion is more frequent in the presence of STIC, these data support STIC as the precursor of extrauterine high-grade serous carcinoma, they provide important clues to the site of origin of high-grade serous carcinoma (ovarian cancer), and can guide further research.
Zhang – Zhang Polynomial of Multiple Linear Hexagonal Chains

An explicit combinatorial expression is obtained for the Zhang-Zhang polynomial (also known as “Clar cover polynomial”) of a large class of pericondensed benzenoid systems, the multiple linear hexagonal chains Mn,m. By means of this result, various problems encountered in the Clar theory of Mn,m are also resolved: counting of Clar and Kekulé structures, determining the Clar number, and calculating the sextet polynomial.