Miracle-dz/UniFAR-FTUs huggingface dataset:
Falls in critical care: a local review to identify incidence and risk

BACKGROUND Patient falls are the most common adverse event in hospitals, resulting in devastating physical, psychological and financial consequences. Therefore the emphasis on falls assessment and prevention is a key priority. Within hospitals those reported at greatest risk of falls are older patients with little known about the factors within critical care. At a local level, a practice development project was identified to review risk factors contributing to falls in critical care. AIMS To identify the incidence of falls within adult critical care and the risk factors most likely to contribute to a fall. METHODS Reported falls incidents were reviewed retrospectively using a local incident reporting system, over a 2-year period from four critical care units. FINDINGS Forty-two incidents were reviewed indicating a low rate of injury and low rate of occurrence (0·99 falls/1000 bed days). The median age of fallers was 58 years and the most common risk factor for falls was confusion or agitation, followed by patients attempting to mobilize against advice. DISCUSSION Critically ill patients were less likely to fall and were more likely to be younger than patients falling on an acute care ward. Neuroscience/trauma critically ill patients were more likely to fall than general critically ill patients; this was expected to be because of the increased presence of confusion or agitation in this group. The local system used to report falls produced difficulties in identifying risk factors in a consistent way. Although limitations exist, this review has enabled the development of more suitable local critical care falls risk factor assessment and interventions to minimize the risk of falling. CONCLUSIONS Fall rates, related injuries and circumstances of falls vary considerably among acute care and critical care specialities. Future work should concentrate on better falls reporting systems and further research should include validating risk factors for critical care falls.
Estimating the Returns to Education

When any expensive machine is erected, the extraordinary work to be performed by it before it is worn out, it must be expected, will replace the capital laid out upon it, with at least the ordinary profits. A man educated at the expense of much labor and time to any of those employments which require extraordinary dexterity and skill, may be compared to one of those expensive machines. The work which he learns to perform, it must be expected, over and above the usual wages of common labor, will replace to him the whole expense of his education, with at least the ordinary profits of an equally valuable capital. It must do this, too, in a reasonable time, regard being had to the very uncertain duration of human life, in the same manner as to the more certain duration of the machine.2
Air pollution as a risk factor for lung cancer

Over the past decade, an increasing body of scientific evidence has accrued associating outdoor air pollution with certain types of cancer. Ambient air, particularly in densely populated urban environments, contains a variety of known human carcinogens such as benzo[α]pyrene and benzene, inorganic compounds (e.g., arsenic and chromium), and radionuclides. Now, it is well recognized that urbanization and lung cancer mortality are linked. This association could arise from differences in the distributions of other lung cancer risk factors, such as smoking and occupational exposures, by degree of urbanization, etc. Air pollution has positively been associated with lung cancer mortality and cardiopulmonary disease mortality, but not with mortality from other causes combined. New studies will need to develop and apply improved epidemiologic methods and to compare the effect of exposure to the pollutant mixtures on lung cancer in different cities while effectively controlling confounding factors including cigarette smoking and diet.
Physiological Responses and Energetics of Competitive Group Exercise in Female Aerobic Gymnasts with Different Levels of Performance

This study investigated the aerobic fitness and physiologic and energetic responses during competitive exercise in aerobic gymnasts. The gymnasts performed a graded treadmill test and competitive group exercises. Energetic response was calculated from oxygen uptake and blood lactate changes. Peak oxygen uptake was similar in International (M = 45.4m · kg−1 · min.−1, SD = 3.9) and National (M = 44.7ml · kg−1 · min.−1, SD = 3.6) level groups. During their competitive routines, total energy and the fractions of aerobic, anaerobic alactic, and anaerobic lactic energy were 1,847.7 (SD = 293.9) and 1,747.3 (SD = 196.7) J · kg−1, 53.5% (SD = 3.1) and 60.3% (SD = 6.1), 25.4% (SD = 5.9) and 21.4% (SD = 5.2), and 21.1% (SD = 5.8) and 18.3% (SD = 4.5) in international and national level athletes, respectively (p > .05). The contribution of anaerobic energy was higher in the international level group (p = .03). It is concluded that the aerobic fitness and absolute energetic and physiological responses of athletes during competitive activities were not different between the aerobic gymnasts groups with different levels of performance, but a higher relative contribution of anaerobic energy was observed in the group with a higher performance level.
Point prevalence of pressure ulcers in three second‐level hospitals in Mexico

Pressure ulcers (PU) are the source of multiple complications and even death. To our knowledge, there is no available data about PU prevalence in Mexico. The objective of this study was to determine the point prevalence of PU in three second‐level hospitals in Mexico. Every adult hospitalised patient was included in each hospital. Age, gender, hospitalisation ward, Braden score, and the number, location and stage of the ulcers encountered were recorded, as well as any pressure relief measures. In total, 294 patients were examined (127 were male); of these, 63 were considered to be at risk. The average age was 48·6 years. The overall prevalence of the PU was 17%. The service with the highest prevalence was the ICU. The most frequent stage was II (32%) and they were most commonly found in the sacrum (74%). The average Braden score of the patients with ulcers was 10, and 21·4% of the patients obtained moderate‐ to high‐risk Braden scores. Of them, 60·3% had ulcers and only 46% had any preventive measures. The prevalence of PU in three hospitals in Mexico is 17%. The most common stage is II and the most commonly affected site is the sacrum. Only 46% of patients with PU had at least one pressure release measure.
Interactive Messages on Video Lottery Terminals and Persistence in Gambling

This study aims to evaluate whether messages presented on a video lottery terminal screen during a gambling session modify players' behaviour. The content of the messages reminded players about the notion of chance and illusion of control in gambling. The hypothesis predicts that the messages will provide players the opportunity to withdraw more rapidly from the game than other players who do not receive these messages. Participants were randomly assigned to three groups (n = 10): a) Messages, b) Breaks, and c) No interruption. The results confirm not only that the presentation of messages influences players' behaviour by inciting them to play fewer games, but also that the presentation of breaks generates the same effect. The links between the effects of breaks on gamblers' behaviour and cognitive theory are discussed while focusing on the control of gambling habits within the context of responsible gambling.
An Approach to Enhance the Conservation-Compatibility of Solar Energy Development

The rapid pace of climate change poses a major threat to biodiversity. Utility-scale renewable energy development (>1 MW capacity) is a key strategy to reduce greenhouse gas emissions, but development of those facilities also can have adverse effects on biodiversity. Here, we examine the synergy between renewable energy generation goals and those for biodiversity conservation in the 13 M ha Mojave Desert of the southwestern USA. We integrated spatial data on biodiversity conservation value, solar energy potential, and land surface slope angle (a key determinant of development feasibility) and found there to be sufficient area to meet renewable energy goals without developing on lands of relatively high conservation value. Indeed, we found nearly 200,000 ha of lower conservation value land below the most restrictive slope angle (<1%); that area could meet the state of California’s current 33% renewable energy goal 1.8 times over. We found over 740,000 ha below the highest slope angle (<5%) – an area that can meet California’s renewable energy goal seven times over. Our analysis also suggests that the supply of high quality habitat on private land may be insufficient to mitigate impacts from future solar projects, so enhancing public land management may need to be considered among the options to offset such impacts. Using the approach presented here, planners could reduce development impacts on areas of higher conservation value, and so reduce trade-offs between converting to a green energy economy and conserving biodiversity.
Randomised trial of impact of model of integrated care and case management for older people living in the community

Abstract Objective: To evaluate the impact of a programme of integrated social and medical care among frail elderly people living in the community. Design: Randomised study with 1 year follow up. Setting: Town in northern Italy (Rovereto). Subjects: 200 older people already receiving conventional community care services. Intervention: Random allocation to an intervention group receiving integrated social and medical care and case management or to a control group receiving conventional care. Main outcome measures: Admission to an institution, use and costs of health services, variations in functional status. Results: Survival analysis showed that admission to hospital or nursing home in the intervention group occurred later and was less common than in controls (hazard ratio 0.69; 95% confidence interval 0.53 to 0.91). Health services were used to the same extent, but control subjects received more frequent home visits by general practitioners. In the intervention group the estimated financial savings were in the order of £1125 ($1800) per year of follow up. The intervention group had improved physical function (activities of daily living score improved by 5.1% v 13.0% loss in controls; P<0.001). Decline of cognitive status (measured by the short portable mental status questionnaire) was also reduced (3.8% v 9.4%; P<0.05). Conclusion: Integrated social and medical care with case management programmes may provide a cost effective approach to reduce admission to institutions and functional decline in older people living in the community. Key messages Responsibility for management of care of elderly people living in the community is poorly defined Integration of medical and social services together with care management programmes would improve such care in the community In a comparison of this option with a traditional and fragmented model of community care the integrated care approach reduced admission to institutions and functional decline in frail elderly people living in the community and also reduced costs
Diacylglycerol kinase-theta is localized in the speckle domains of the nucleus.

It is well established that the nucleus is endowed with enzymes that are involved in lipid-dependent signal transduction pathways. Diacylglycerol (DAG) is a fundamental lipid second messenger that is produced in the nucleus. Previous reports have shown that the nucleus contains diacylglycerol kinases (DGKs), i.e., the enzymes that, by converting DAG into phosphatidic acid (PA), terminate DAG-dependent events. Here, we show, by immunofluorescence staining and confocal analysis, that DGK-theta localizes mainly to the nucleus of various cell lines, such as MDA-MB-453, MCF-7, PC12, and HeLa. Nuclear DGK-theta co-localizes with phosphatidylinositol 4,5-bisphosphate (PIP(2)) in domains that correspond to nuclear speckles, as revealed by the use of an antibody to the splicing factor SC-35, a well-established marker for these structures. The spatial distribution of nuclear DGK-theta was dynamic in that it was affected by inhibition of mRNA transcription with alpha-amanitin. Immuno-electron microscopy analysis demonstrated that DGK-theta, PIP(2), and phosphoinositide-specific phospholipase Cbeta1 (PLCbeta1) associated with electron-dense particles within the nucleus that correspond to interchromatin granule clusters. Cell fractionation experiments performed in MDA-MB-453, HeLa, and PC12 cells showed a preferential association of DGK-theta with the nucleus. Western blots demonstrated that DGK-theta was enriched in the nuclear matrix fraction prepared from MDA-MB-453 cells. Immunoprecipitation experiments with an antibody to PLCbeta1 revealed in MDA-MB-453 cells an association between this enzyme and both DGK-theta and phosphatidylinositol phosphate kinase Ialpha (PIPKIalpha). Our findings strengthen the contention that speckles represent a crucial site for the nuclear-based inositol lipid cycle. We may speculate that nuclear speckle-located DGK-theta, on cell stimulation with an agonist, converts to PA the DAG derived from PLCbeta1-dependent PIP(2) hydrolysis.
Optimal power allocation for achievable secrecy rate in an untrusted relay network with bounded channel estimation error

The objective of this paper is to maximize the secrecy rate in an untrusted relay network with imperfect channel state information (CSI). Considering bounded channel estimation error in cooperative jamming network, we optimize the power allocation for confidential and jamming signals to maximize the instantaneous secrecy rate. The upper and lower bounds of achievable secrecy rate are analyzed. The ergodic secrecy rate (ESR) is further derived to evaluate the maximum average secrecy rate. And the optimal power allocation is also studied based on ESR. Numerical results show optimal power allocation can increase both instantaneous secrecy rate and ESR, and at higher SNR, the impact of channel estimation error can be neglected for the maximum ESR, which is asymptotically approaches to the upper bound.
Rural Development and Strategies for Sustainable Agrarian Livelihood

This research aims to explore how rural development under the policy of market-oriented economy effects local people in terms of economic, social and cultural practices, and how they adapt themselves to those changes to sustain their livelihood strategies through focusing on Ban Huaxieng of Xaithany district as a case study. This study analyzes both primary data and secondary data and applies both quantitative and qualitative analysis methods. Four methods are applied for primary data: household survey, participant observation, life history and indepth interview. This research focuses on three main parts: first, Ban Huaxieng and policy implementation of rural development; second, livelihood diversification as new livelihood strategies; and third, changing social and cultural practices under development. As a result of analyzing this case study, two main findings are discovered. Firstly, diversification of livelihood is considered as new livelihood strategies under rural development along with the mechanism of market economy. Secondly, rural development can improve living condition but creates contradictions; particularly, development under the market mechanism has created unintended consequences, which can endanger some agrarian households’ sustainable livelihood.
Selection and Specialization in the Evolution of Marriage Earnings Gaps

We examine changes in marriage and earnings patterns across four cohorts born between 1936 and 1975 using data from Survey of Income and Program Participation panels linked to administrative data on earnings. We find that, for both men and women, marriage has become increasingly positively associated with education and earnings potential. We compare ordinary least squares and fixed-effect estimates of the earnings differential associated with marriage. We find that the marriage earnings gap fell for women in fixed-effect estimates, implying that the impact of specialization has diminished over time. We also find that increasingly positive selection into marriage overstates the reduction in the marriage earnings gap. Although marriage is no longer associated with lower earnings among women in our most recent cohort, the motherhood gap remains large. Among men, we find that the marriage premium actually increases for more recent birth cohorts in fixed-effects regressions.
Endothelial microparticles correlate with endothelial dysfunction in obese women.

CONTEXT Cell-derived microparticles are supposed to be involved in atherogenesis. OBJECTIVE This study aimed to evaluate circulating microparticles in obese women and their relation with anthropometric measures and endothelial dysfunction. DESIGN, SETTING, AND PARTICIPANTS Forty-one obese [body mass index (BMI) > 30 kg/m(2)] women and 40 normal weight (BMI < 25 kg/m(2)) age-matched women were studied. Flow cytometry was used to assess microparticles by quantification of circulating endothelial microparticles (EMP, CD31+/CD42b-) and platelet microparticles (PMP, CD31+/CD42b+) in peripheral blood; endothelium-dependent flow-mediated vasodilation (FMD) was evaluated in the right brachial artery after reactive hyperemia. RESULTS Compared with lean women, obese women presented significantly higher numbers of EMP and PMP, and reduced FMD. BMI did not correlate with either EMP (r = 0.02, P = 0.9) or PMP (r = -0.07, P = 0.645), whereas waist-to-hip ratio (WHR) showed significant correlation with both microparticles (r = 0.699, P < 0.001; r = 0.373, P = 0.016, respectively). Both EMP and PMP counts positively correlated with impairment of FMD in obese women. Multivariate analysis correcting for age, anthropometric indices, lipid parameters, and PMP identified EMP as the only independent predictor for impaired endothelial-dependent vasodilation (P = 0.003). CONCLUSIONS EMP are elevated in obese women and independently involved in the pathogenesis of endothelial dysfunction. WHR is the anthropometric measure more closely related to EMP and endothelial dysfunction.
A case of Giardia lamblia proctitis presenting in a V.D. clinic.

Attendance at a British venereal disease clinic does not require referral from a family doctor; accordingly, when a patient presents spontaneously, there is a reasonable assumption that he suspects sexually acquired disease. Asian immigrants are still prone to conceal the truth of their sexual activities, particularly if homosexual activity is involved, and it is against this background that the following case is recorded.
Hypnotizability Modulates the Cardiovascular Correlates of Subjective Relaxation

Abstract Mean values and the spectral variability of heart rate (HRV), blood pressure, and skin blood flow were studied in high and low hypnotizable subjects during simple relaxation. Similar subjective relaxation was reported by highs and lows. A parasympathetic prevalence (indicated by a higher High-Frequency component of HRV and a lower High/Low-Frequency ratio) and lower renin-angiotensin activity (indicated by a lower Very-Low-Frequency component of HRV) could be attributed to highs with respect to lows. Hypnotizability did not affect blood pressure and its variability and modulated the skin blood flow across the session only in lows. The findings confirm that relaxation cannot be defined solely on cardiovascular parameters and also indicate that hypnotizability modulates cardiovascular activity during simple relaxation and suggest it may have a protective role against cardiovascular disease.
Tolerance to Elevated Temperature and Ocean Acidification of the Larvae of the Solitary Corals Fungia fungites (Linnaues, 1758) and Lithophyllon repanda (Dana, 1846)

Increase in atmospheric CO2 is the main driver of global climate change and is projected to elevate sea surface temperature by at least 2°C and to decrease oceanic pH by 0.3 to 0.4 units by the end of the century. These factors seriously threaten coral reef ecosystems worldwide. In Okinawa, solitary corals are an important feature of the coral community structure. While previous studies on the effects of ocean warming (OW), ocean acidification (OA) and its combination on larval survival focused on colonial coral species, the present study assessed the effect of high temperature on larvae from solitary corals. In this study, we examined the influence of OW (control = 28°C; control +3 = 31°C; control + 6 = 34°C) and OA (control, pCO2 = 400 to 500 μatm; medium, pCO2 = 1000 to 1300 μatm; high, pCO2 = 1700 to 2200 μatm) on the larval survival of two solitary corals, Fungia fungites and Lithophyllon repanda for eight days. Results showed that F. fungites was neither affected by OW, OA, nor its combination. Similarly, survival of L. repanda was not affected by OA however it was significantly affected by temperature. Temperature tolerance varies between species; L. repanda (+3°C above ambient) has lower tolerance than F. fungites (+6°C above ambient). This observation suggests that fungiid larvae had higher tolerance to elevated temperature stress relative to other scleractinian corals. With the projected increase in OW and OA in the future, fungiidsmay retain good potential to widely disperse and successfully recruit to natal and other neighbouring reefs.
The Life Stories of Motherhood Among Divorced Women in Taiwan

&NA; The purpose of this study is to delineate life stories of motherhood among divorced women, and to answer the following research questions: (1) How does their motherhood develop? (2) How does divorce impact on motherhood? (3) How do mothers cope with divorce? (4) What does motherhood mean for these mothers? Through in-depth interviews, inter-subjective interaction and story writing, a total of six women's stories were collected. The following titles were found for stories of motherhood among these divorced women: (1) Walking in balanced steps. (2) Becoming a single mom is not a surprise. (3) Seeking reunion for the sake of the kids. (4) Grieving for the loss of an integrated family. (5) I found myself. (6) A diamond becomes a stone. Motherhood was found not to be a set of stable role expectations, but to be transforming and shaping through reflective thoughts on motherhood, which were impacted by interactions between the mothers and their children, and by the social contexts they encountered. The impact of divorce on motherhood was found to be both positive and negative. Some families even enjoyed life more after discontinuing their chaotic marriage. Still, motherhood of divorced women was full of challenges and disadvantages due to a concrete double burden and invisible social persecution. Invisible social persecution of divorce was performed through the mechanism of stigma. Stigma was transmitted through the value myths of motherhood, which are passed from generation to generation through parent-child interactions. Stigmatized divorce made these mothers feel more guilt and powerlessness. Divorced motherhood was therefore found to be intertwined with processes of caring and grieving. In this research, however, community resources were found to be very helpful in supporting these families, and were able to empower them to overcome the myths. Life story research was found to be an effective support, inspiring deeper reflection, and empowering the storyteller. The researcher therefore suggests that the life story research method be included in the nursing curriculum. Finally, the researcher goes on to discuss some issues regarding methodology for life stories and qualitative research.