Miracle-dz/UniFAR-FTUs huggingface dataset:
XAS Analysis of Reactions of (Arylimido)vanadium(V) Dichloride Complexes Containing Anionic NHC That Contains a Weakly Coordinating B(C6F5)3 Moiety (WCA-NHC) or Phenoxide Ligands with Al Alkyls: A Potential Ethylene Polymerization Catalyst with WCA-NHC Ligands

(Arylimido)vanadium(V) dichloride complexes containing anionic N-heterocyclic carbene (NHC) ligands that contain weakly coordinating B(C6F5)3 moieties (WCA-NHC) of the type [V(NAr)Cl2(WCA-NHC-Ar′)] (5, Ar = 2,6-Me2C6H3, Ar′ = 2,6-iPr2C6H3) showed significant catalytic activity for ethylene polymerization in the presence of Al cocatalysts (MAO and AliBu3); the activity by the 5–MAO catalyst (19 500 kg-PE/mol-V·h; TOF 11 600 min–1) is the highest among those reported using the other (imido)vanadium(V) complexes in the presence of MAO, and the 5–AliBu3 catalyst showed higher activity (66 000 kg-PE/mol-V·h; TOF 39 200 min–1). The V K-edge X-ray absorption near-edge structure (XANES) analyses (in toluene) strongly suggest the formation of certain vanadium(III) species by reduction with AliBu3 accompanying structural changes; the EXAFS analysis suggests the presence of the arylimido ligand and one V–Cl bond (2.34 ± 0.04 Å), which is longer than those [2.1901(8)–2.2462(8) Å] in the reported (imido)vanadium(V) complexes. The XANES analysis of [V(NAr)Cl2(OAr)] strongly suggests the formation of the other vanadium(III) species by reduction with Me2AlCl or Et2AlCl, and the EXAFS analysis suggests the presence of the arylimido ligand and two V–Cl bonds (2.45 ± 0.03 Å). The XANES spectra showed no significant changes in both the pre-edge peak(s) and the edge peak when these complexes were treated with MAO, suggesting that the basic geometry and the high oxidation state were preserved under these conditions.
High-throughput continuous dielectrophoretic separation of neural stem cells

We created an integrated microfluidic cell separation system that incorporates hydrophoresis and dielectrophoresis modules to facilitate high-throughput continuous cell separation. The hydrophoresis module consists of a serpentine channel with ridges and trenches to generate a diverging fluid flow that focuses cells into two streams along the channel edges. The dielectrophoresis module is composed of a chevron-shaped electrode array. Separation in the dielectrophoresis module is driven by inherent cell electrophysiological properties and does not require cell-type-specific labels. The chevron shape of the electrode array couples with fluid flow in the channel to enable continuous sorting of cells to increase throughput. We tested the new system with mouse neural stem cells since their electrophysiological properties reflect their differentiation capacity (e.g., whether they will differentiate into astrocytes or neurons). The goal of our experiments was to enrich astrocyte-biased cells. Sorting parameters were optimized for each batch of neural stem cells to ensure effective and consistent separations. The continuous sorting design of the device significantly improved sorting throughput and reproducibility. Sorting yielded two cell fractions, and we found that astrocyte-biased cells were enriched in one fraction and depleted from the other. This is an advantage of the new continuous sorting device over traditional dielectrophoresis-based sorting platforms that target a subset of cells for enrichment but do not provide a corresponding depleted population. The new microfluidic dielectrophoresis cell separation system improves label-free cell sorting by increasing throughput and delivering enriched and depleted cell subpopulations in a single sort.
Impact of Red Beetroot Juice on Vascular Endothelial Function and Cardiometabolic Responses to a High-Fat Meal in Middle-Aged/Older Adults with Overweight and Obesity: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial

ABSTRACT Background High-fat meal (HFM) consumption may induce transient postprandial atherogenic responses, including impairment of vascular endothelial function, in individuals with overweight/obesity. Red beetroot juice (RBJ) may modulate endothelial function and other measures of cardiometabolic health. Objective This study investigated the impact of acute and chronic RBJ consumption, including nitrate-dependent and -independent effects, on postprandial endothelial function and other cardiometabolic responses to a HFM. Methods Fifteen men and postmenopausal women with overweight/obesity were enrolled in this randomized, double-blind, placebo-controlled, 4-period, crossover clinical trial. Following an overnight fast, participants underwent baseline assessment of endothelial function (reactive hyperemia index; RHI) and hemodynamics, and biological sample collection. In random order, participants consumed 70 mL (acute visit) of: 1) RBJ, 2) nitrate-free RBJ (NF-RBJ), 3) placebo + nitrate (PBO + NIT), or 4) placebo (PBO), followed by a HFM. RHI was remeasured 4 h post-HFM, and hemodynamic assessment and biological sample collection were performed 1, 2, and 4 h post-HFM consumption. Participants consumed treatments daily for 4 wk (chronic visit), and assessments were repeated before/after the HFM (without consuming treatments). Results HFM consumption did not induce significant impairment of postprandial RHI. No significant differences in RHI were detected across treatment groups following acute or chronic exposure, despite increases in circulating nitrate/nitrite (NOx) concentrations in the RBJ and PBO + NIT groups compared with PBO and NF-RBJ (P < 0.0001 for all time points at the acute visit; P < 0.05 for all time points at the chronic visit). Although the HFM led to significant alterations in several secondary outcomes, there were no consistent treatment effects on postprandial cardiometabolic responses. Conclusions HFM consumption did not impair postprandial endothelial function in this population, and RBJ exposure did not alter postprandial endothelial function or other outcomes despite increasing NOx concentrations. This trial is registered at clinicaltrials.gov as NCT02949115.
Presymptomatic Retinal Sensitivity Changes in Intermediate Age-Related Macular Degeneration Associated With New Retinal Fluid

Purpose To determine whether change in retinal sensitivity in areas with subretinal or intraretinal fluid secondary to age-related macular degeneration (AMD) precedes visual symptoms. If confirmed, retinal sensitivity testing could be used for home monitoring in AMD. Methods Individuals with intermediate AMD enrolled in a longitudinal study were seen every 6 months and underwent best-corrected visual acuity testing (BCVA), spectral domain–optical coherence tomography (SD-OCT), and microperimetry. Asymptomatic individuals who developed incidental, reading center–determined retinal fluid detected on SD-OCT were identified. The point-wise sensitivity (PWS) at the time of fluid detection was compared with 6 and 12 months prior. Results Fourteen of 161 individuals developed fluid without symptoms. PWS over fluid areas at detection was reduced compared with 6 (difference −2.04 dB, P < 0.001) and 12 months (−2.27 dB, P < 0.001) prior. PWS over fluid areas was reduced compared with perifluid areas (difference −1.02 dB, P = 0.03), peripheral areas (−1.51 dB, P < 0.001), nonprogressed fellow eyes (−1.49 dB, P = 0.006), and nonprogressed age-matched intermediate AMD eyes (−2.29 dB, P = 0.001). No difference in BCVA was observed in eyes developing fluid compared to eyes that do not develop fluid (P = 0.76). Conclusions Retinal areas with fluid on SD-OCT had a corresponding reduction in retinal sensitivity at the time of fluid detection compared with 6 and 12 months prior, in asymptomatic intermediate AMD without change in BCVA. Translational Relevance Development of self-monitoring tools to detect changes in retinal sensitivity may be helpful for early detection of retinal fluid suggestive of progression to neovascular AMD before acuity is affected.
Adapting the Appropriate RTT Timeout of TCP NewReno in Submarine Communication Networks

In the future, aquaculture and aquaponics could play a more important role to meet the increasing demand of a growing world population and meet future demand for food. Underwater Wireless sensor networks (UWSNs) are increasingly used to measure various water parameters in order to monitor the evolution of an aquaculture. Adapting this system network in this environment requires several studies for reliable communication. This work is the continuation of many improving studies of the performance of Transmission Control Protocol (TCP) in marine environment. It aims at adapting the NewReno TCP in an UWSN by finding the appropriate parameters. Moreover, in this paper we deal with another parameter in order to evaluate its effect on the performance of this TCP in UWSNs. We propose a performance improvement of the NewReno TCP by fitting the Round Time Trip (RTT) value in accordance with the UWSN characteristics. This new adaptation is simulated on the environment of the Aqua-sim simulator of Ns2 tool. The results show that with the new parameter setting of NewReno TCP, performances in terms of packet transmission gain and packet delivery retransmission rates give better results compared to those obtained while using the original NewReno TCP protocol in a UWSN. 
Preschool Teachers' Opinions about Individualized Education Plan

Individualizirani pristup odgojno-obrazovnim potrebama djece s teskocama u razvoju znacajno utjece na kvalitetu ukljucenosti, njihovog napretka i socijalnih kompetencija, a individualizirani odgojno-obrazovni program temelj je rada s ovom djecom. Međunarodno je priznat i zakonski regulirana njegov znacaj i za djecu s teskocama u razvoju u mnogim zemljama, dok u Hrvatskoj ne postoji zakonska regulativa u ranom i predskolskom odgoju i obrazovanju koja obvezuje odgajatelja na izradu i provođenje. Cilj rada bio je ispitati misljenja odgajatelja o individualiziranim odgojno-obrazovnim programima za djecu s teskocama i utvrditi postoje li razlike u odnosu na njihova socio-demografska obilježja. U istraživanju je sudjelovao 141 odgajatelj. Koristena je Skala stava odgajatelja prema individualiziranom odgojno-obrazovnom programu (IOOP). Dobivena su dva faktora: (1) spremnosti odgajatelja za primjenom IOOP-a i (2) osposobljenost za primjenom IOOP-a. Odgajatelji izražavaju spremnost izrađivati i provoditi IOOP- a, ali se ne osjecaju dovoljno osposobljenima. Samo 14% odgajatelja izrađuje IOOP za djecu s teskocama.
Disease characteristics of systemic sclerosis among Egyptian patients

Introduction Scleroderma, or systemic sclerosis (SSc), is a chronic connective tissue disease that has been classified as one of the autoimmune rheumatic diseases. The usual hallmarks of SSc are autoimmunity, inflammation, widespread small-vessel vasculopathy affecting multiple vascular beds, and progressive interstitial and vascular fibrosis in the skin and internal organs. Aim of the work The aim of the study was to determine the disease characteristics and frequency of different clinical manifestations among Egyptian patients. Patients and methods Seventy-five patients with SSc, all fulfilling the criteria of the American College of Rheumatology for classification of scleroderma, were selected for this study. They were being followed up in Cairo University Internal Medicine department. The patients′ data were collected by a review of their medical records. We compared the frequency of symptoms in scleroderma patients with both diffuse cutaneous and limited cutaneous sclerosis (dcSSc and lcSSc). Results Fourteen patients out of 75 (18.7%) had dcSSc and 61/75 (81.3%) had lcSSc. We found that within the limited subtype 11/61 (18%) were male and 50/61 (82%) were female, with a male to female ratio of 1: 4.6. Within the diffuse subtype, 3/14 (21.4%) were male and 11/14 (78.6%) were female, with a male to female ratio of 1: 3.7. Raynaud′s phenomenon was the first presenting manifestation (in 77.3%), followed by arthritis (in 12%) and skin tightness (in 9.3%). Conclusion SSc is more common in the female population than in the male population. lcSSc is more common than dcSSc.
The acute effect of match-play on hip range of motion and isometric strength in elite tennis players

Background Groin injuries are some of the most common injuries tennis players suffer. Several factors (e.g., post-match decrease in hip adductor (ADD) strength) have been proposed as possible mechanisms for increasing the incidence of this type of injury. However, the risk factors of developing groin injuries after a tennis match have not yet been delineated. Objective The aim of this study was to determine the effect of tennis match-play on isometric ADD and abductor (ABD) strength and passive hip range of motion (ROM). Methods Twenty-six male tennis players (20.30 ± 4.98 years) took part in this study. Participants completed an evaluation of strength and flexibility hip measurements before and after a simulated tennis match. Dominant and non-dominant passive hip ROM, ADD and ABD isometric strength, and the ADD/ABD strength ratio were measured before and immediately post-match. A global positioning system (GPS) and a session rating of perceived exertion (RPE) were used to assess the locomotive demands and internal match load. Results Isometric dominant ADD strength (17.8%, p ≤ 0.01) and ADD/ABD strength ratio (11.6%, p = 0.04) were lower post-match compared to the pre-match values. No between-limbs differences were observed for isometric ADD strength, ABD strength, and passive hip ROM tests. RPE showed an expected increase between pre- vs. post-match (pre- vs. post-warming-up, 3.42 ± 2.08 vs. 5.62 ± 2.29, p < 0.01). In addition, a significant relationship between ADD strength and the volume of tennis practice per week was found, stablishing that tennis players with lower volume of training per week suffered a reduction in ADD strength in their dominant limb after match-play (r = 0.420, p = 0.04). Conclusion The assessment of ADD strength and the ADD/ABD strength ratio in the dominant limb may be considered a post-match tool that can be used to identify players who require rest and additional recovery strategies before competing again.
On the Light Penetration in Natural Sands

Sand-textured soils are found in a wide range of landscapes, from coastal areas to dune fields. The quantification of light penetration through these soils is of considerable interest not only for remote sensing applications, but also for agricultural, ecological and geophysical studies. Despite its importance, however, the literature on this topic is still scarce. Moreover, the available light penetration (transmittance) datasets for these soils are affected by experimental and modeling limitations. These include, for instance, the use of samples with morphological and mineralogical characteristics markedly different from those of naturally occurring sand-textured soils. To overcome these limitations and strengthen the current knowledge about light penetration in these soils, commonly referred to as natural sands, we propose the use of a predictive in silico experimental framework supported by measured data. Our findings demonstrate that it is necessary to properly account for the varying particle distributions and the iron oxide contents of natural sands in order to obtain penetration depth estimations that can be reliably employed in investigations involving these soils. In addition, our in silico experiments allow for a diversified assessment of the light transmission profiles of natural sands at different depths with respect to spectral and angular dependencies.
Comparison of Sentinel-3 Slstr Sst Product with Shipboard Skin Sst Measurements

Sea surface temperature (SST) is an important indicator for climate change. Nowadays many sensors in orbit have the capacity of SST observations. Long-term climate data record of global SST requires satellite SST products with high accuracy and stability. In order to evaluate the quality of satellite SST products, proper collection of in situ sea surface skin temperature is needed. The infrared SST autonomous radiometer (ISAR) has been deployed on the research vessel Dong Fang Hong II of Ocean University of China since 2009. The ISAR data collected during five cruises are used to validate the Level-2 WST products from Sea and Land Surface Temperature Radiometer (SLSTR). The comparison results show negative bias of 0.085K and standard deviation of 0.356K. Due to the influence of the weather conditions and short temporal extent of the SLSTR L2 WST archived, only 148 match-ups are produced. Further studies will be carried out with more available data from in situ and satellites.
Alcohol Consumption and Severity of Polyneuropathy by Electrophysiological Study

Objective: To study severity of polyneuropathy by EPS and its correlation with alcohol consumption. Methodology: Chronic alcoholic subjects who were above 18 years of age included in the study. All subjects were subject to EPS study and categorized in 4 different types of severity. Alcohol consumption of subjects were noted. TLDE was calculated . Correlation of severity of polyneuropathy by EPS and alcohol consumption was done. Outcome measures: Severity of polyneuropathy by EPS with respect to type, duration and amount of alcohol consumption. Study design: Hospital based, cross sectional study. Conclusion: Most of subjects 54(51.4%) consumed country made liquor; followed by 13(12.3%) consumed beer. 76.2% subjects had daily alcohol intake more than 100g/day. Duration of alcohol use was at least 2 years for all subjects. Majority 61(58.09%) of them consumed alcohol for 6 to 10 years. On EPS the average number of years of alcohol consumption in 'Severe' category was highest with 15.94±5.76 yr, while for cases falling in 'Borderline' category, it was lowest with 7.0476±2.01yr so this study concludes that Patient who consumed country liquor for longer time and larger amount had more severe type of neuropathy.
Inorganic nitrogen availability alters Eucalyptus grandis receptivity to the ectomycorrhizal fungus Pisolithus albus but not symbiotic nitrogen transfer.

Forest trees are able to thrive in nutrient poor soils in part because they obtain growth-limiting nutrients, especially nitrogen (N), through mutualistic symbiosis with ectomycorrhizal (ECM) fungi. Addition of inorganic N into these soils is known to disrupt this mutualism and reduce the diversity of ECM fungi. Despite its ecological impact, the mechanisms governing the observed effects of elevated inorganic N on mycorrhizal communities remain unknown. We address this by using a compartmentalized in vitro system to independently alter nutrients to each symbiont. Using stable isotopes, we traced the nutrient flux under different nutrient regimes between Eucalyptus grandis and its ectomycorrhizal symbiont, Pisolithus albus. We demonstrate that giving E. grandis independent access to N causes a significant reduction in root colonization by P. albus. Transcriptional analysis suggests that the observed reduction in colonization may be caused, in part, by altered transcription of microbe perception genes and defence genes. We show that delivery of N to host leaves is not increased by host nutrient deficiency but by fungal nutrient availability. Overall, this advances our understanding of the effects of N fertilization on ECM fungi and the factors governing nutrient transfer in the E. grandis - P. microcarpus interaction.
Role of Plasma and Urinary YKL 40 in Early Diagnosis of Nephropathy in Type 2 Diabetic Patients

Background:Diabetic Nephropathy is a microvascular complication of Type 2 diabetes mellitus (T2DM) and is an important cause of end stage renal disease (ESRD). The importance of YKL 40 in early diagnosis of diabetic nephropathy is undertaken in this study. Aim:The aim of our Study is to assess usefulness of YKL 40 in early diagnosis of nephropathyintype2 diabetic patients Materials and Methods:20 Type2 T2DM patients in the age group of 35 to 60 were selected for this study and the same were compared with age matched 20 healthy controls. Plasma and urine YKL-40 with complete Haemogram andHbA1C were done by standardised methods. Results:In this study we found that both plasma and urine YKL 40 levels were significantly higher in type 2 diabetes mellitus patients. Besides, YKL-40positively and significantly correlated with important measured renal parameters. Conclusion:YKL-40 is a useful marker in the early diagnosis of nephropathy in T2DM patients.
Assessment of the Level of Gastrointestinal Parasites Infection among Food Vendors in Minna, North Central Nigeria.

Aim : This study was undertaken to access the intestinal parasitic profile of food vendors in Minna Nigeria. Study Design: This is a cross-sectional study conducted in Minna the capital of Niger state, North central Nigeria. Sample sizes were determined at random from the food vendors selling ready to eat food. Place and Duration of Study: Samples were collected from the food vendors in Minna between June and December 2012. Methodology: Samples were assayed for intestinal parasites using direct wet mount and formalin-ethyl acetate sedimentation techniques. Results: This study showed that 104 samples out of 116 (89.66%) were positive for intestinal parasites; 70 samples (67.31%) represented single infections and 34 (32.69%) mixed infections. Ascaris lumbricoides eggs were found in 11 (10.58%), Hookworm 10
Clinical and neurocognitive issues associated with Bosch‐Boonstra‐Schaaf optic atrophy syndrome: A case study

Nuclear receptor subfamily 2 group F member 1 (NR2F1) is an orphan receptor and transcriptional regulator that is involved in neurogenesis, visual processing and development, and cortical patterning. Alterations in NR2F1 cause Bosch‐Boonstra‐Schaaf optic atrophy syndrome (BBSOAS), a recently described autosomal dominant disorder characterized by intellectual and developmental disabilities and optic atrophy. This study describes the clinical and neurocognitive features of an individual with a de novo nonsense variant in NR2F1 (NM_005654.5:c.82C > T, p.Gln28*), identified by whole exome sequencing. The patient was diagnosed with autism spectrum disorder (ASD) and unlike most previously reported cases, he had no developmental delay, superior verbal abilities (verbal IQ = 141), and high educational attainment despite reduced nonverbal abilities (nonverbal IQ = 63). He had optic nerve hypoplasia with minimal visual impairment as well as mild dysmorphic features. Compared to both age‐matched individuals with ASD and healthy controls, the patient showed reductions in manual motor speed, accuracy of saccadic eye movements, and rates of successful behavioral response inhibition. Although the majority of previously reported cases of BBSOAS have been associated with more global intellectual dysfunction, we report on a patient with selective disruption of nonverbal abilities and superior verbal abilities.
PhABC: A Hybrid Artificial Bee Colony Strategy for Pairwise test suite Generation with Constraints Support

Software testing becoming significant part of our daily life due to a software-development process that led to increase the components number and the associated time. Due to the financial resources and time constraints, practically exhaustive testing is hopeless. For this reason, numerous researchers have adopted pairwise testing to decrease the exhaustive number of test cases. Pairwise testing is one of a powerful Combinatorial Testing Technique (CTT) that used widely for test data generation. Various existing research works were developed using a meta-heuristic algorithm as a basis for pairwise testing strategies. Supplementing to earlier research work, this paper proposed a new pairwise test suite generation called pairwise hybrid artificial bee colony (PhABC) strategy based on hybridize of an artificial bee colony (ABC) algorithm with a particle swarm optimization (PSO) algorithm. The output of PhABC is a set of promising optimal test set combinations. The results of the experiments showed that PhABC outperformed and yielded better test sets than other existing other research strategies even with the existing constraints.