Miracle-dz/UniFAR-FTUs huggingface dataset:
Design of a new mm-wave antenna fed by CPW inductively coupling for mining communication

A new concept of coplanar waveguide (CPW) exciting of mm-wave slot antenna has been presented. The antenna feeding is ensured by the coupling from the coplanar line to the slot radiating element via an inductively excitation located within the ground plane to which the coplanar line is connected. Simulated results show good performances in terms of bandwidth and gain at 60 GHz. Through the adjustment of different parameters of the exciting slots, good impedance matching is achieved. This kind of antenna can be integrated easily with other active devices. The designed antenna is suitable for wireless communication in underground mine.
SEGUE: A SPECTROSCOPIC SURVEY OF 240,000 STARS WITH g = 14–20

The Sloan Extension for Galactic Understanding and Exploration (SEGUE) Survey obtained ≈240,000 moderate-resolution (R ∼ 1800) spectra from 3900 Å to 9000 Å of fainter Milky Way stars (14.0 < g < 20.3) of a wide variety of spectral types, both main-sequence and evolved objects, with the goal of studying the kinematics and populations of our Galaxy and its halo. The spectra are clustered in 212 regions spaced over three quarters of the sky. Radial velocity accuracies for stars are at g < 18, degrading to at g ∼ 20. For stars with signal-to-noise ratio >10 per resolution element, stellar atmospheric parameters are estimated, including metallicity, surface gravity, and effective temperature. SEGUE obtained 3500 deg2 of additional ugriz imaging (primarily at low Galactic latitudes) providing precise multicolor photometry (σ(g, r, i) ∼ 2%), (σ(u, z) ∼ 3%) and astrometry (≈0.″1) for spectroscopic target selection. The stellar spectra, imaging data, and derived parameter catalogs for this survey are publicly available as part of Sloan Digital Sky Survey Data Release 7.
Controversy and Conflict in the Treatment of Acute Decompensated Heart Failure: Limited Role for Nesiritide

The use of nesiritide for acute decompensated heart failure (ADHF) has been clouded with controversy since its approval in 2001. Extensive marketing and many review articles have established this drug as a safe and superior product to current standards. However, its safety has been called into question by the results of a meta‐analysis, and its superiority of important outcomes (length of stay, mortality, decreased readmission rate) has never been proved by a randomized trial against agents with similar vasodilator properties (e.g., nitroglycerin). A review of the available literature on nesiritide in the areas of mortality, renal effects, retrospective studies, use in off‐label indications, length of stay, and mortality is presented and illustrates why its use should be limited or even eliminated. After review of this article, the reader should be able to answer the question—if nesiritide had never been approved for use in patients with ADHF, would we have missed it? —with a negative reply.
Ingrown Toenail: Histopathologic and Immunohistochemical Study

Although ingrown toenail (IT) is a common problem, the morphologic alterations presented in this condition have rarely been presented in literature. We have studied 14 cases from 12 different patients and studied the biopsies of all of them, not only with routine techniques but also with histochemical stains (Masson trichrome, periodic acid-Schiff, and Gram) and with immunohistochemical techniques mindbomb homolog-1 (MIB-1), p63, D2-40, and AE1-AE3). The patients were clinically classified into 4 stages (1, 2a, 2b, and 3). The main changes evidenced were ingrowing of the squamous epithelium (either from the matrix or mostly from the hyponichium) and chronic plasma-cell rich inflammation with prominent vascularization. The intensity of these changes varied depending on the stage: whereas they were mild in stages 1 and 2a, they were prominent in stages 2b and 3. In advanced stages, the epithelial nests showed certain dyskeratosis. The expression of MIB-1 was, nevertheless, only basal and parabasal. p63 was intensively expressed by the epithelial nests. We therefore conclude that (a) IT shows epithelial ingrowing with accompanying granulation tissue; (b) according to the clinical stage of the disease, this pattern can be more or less complex; (c) in advanced stages of IT, the pattern can mimic a well-differentiated squamous cell carcinoma; (d) MIB-1 is not helpful in distinguishing IT from squamous cell carcinoma; (e) the high expression of p63 by the ingrowing epithelium should not be the source of a misdiagnosis of malignancy.
More than a sidekick: the IL‐6 family cytokine IL‐11 links inflammation to cancer

IL‐11, a member of the IL‐6 family of cytokines, exerts pleiotropic activities by stimulating hemopoiesis and thrombopoiesis, regulating macrophage differentiation, and conferring mucosal protection in the intestine. These effects are mediated by a multimeric complex comprising the ligand‐binding IL‐11Rα and the ubiquitously expressed gp130R β‐subunit, which together, trigger intracellular signaling and engagement of Stat3. In turn, activated Stat3 promotes cell survival and proliferation as well as immune responses associated with inflammatory diseases and tumor progression. IL‐6 and IL‐11 compete for interaction with gp130, resulting in tissue‐specific functions depending on the expression patterns of their respective α‐subunit receptors. Although traditionally, IL‐6 has been associated with aberrant Stat3 activation and associated pathologies, here, we discuss newly emerging roles for IL‐11 in linking inflammation to cancer progression. We propose that in light of the recurrence of persistent STAT3 activation and elevated IL‐11 expression in inflammation‐associated gastrointestinal cancers in humans, inhibition of Stat3 or pharmacologically, more amenable upstream molecules such as IL‐11 may represent novel, therapeutic targets.
Postharvest Control of Botrytis cinerea Infections on Cut Roses Using Fungistatic Storage Atmospheres

The effectiveness of fungistatic atmospheres for postharvest control of Botrytis cinerea Pers. infections on cut rose flowers (Rosa hybrids L.) was investigated. Storing cut 'Sonia', 'Royalty', and 'Gold Rush' roses at 2.5C with 10% CO2 for 5 days, followed by 2 days of cold storage in air, reduced the number of B. cinerea lesions that developed on inoculated and noninoculated flower petals by 77% and 82%, respectively, compared to cold storage for 7 days in air. Higher CO2 concentrations and longer CO2 treatment times reduced disease severity further, but resulted in unacceptable leaf discoloration on some cultivars. No deleterious effects of CO 2-enriched storage atmospheres on flower quality, weight gain, or vase life were observed. Storage at 2.5C for 7 days in 2 µl SO 2/liter reduced B. cinerea infections on inoculated and noninoculated flowers by 53% and 43%, respectively. No deleterious effects on flower quality, weight gain, or vase life were observed. Higher SO 2 levels reduced disease severity further, but caused bleaching of the petal margins and necrosis around leaf wounds. Botrytis cinerea is a serious pathogen of rose flowers and other cut flower crops. Infections first appear as water-soaked spots or flecks on the flower petals. As the lesions coalesce, the infected petals turn brown and wither. Eventually, the entire flower may rot off at the receptacle. B. cinerea infections often cannot be detected at harvest, but develop rapidly under the moist conditions encountered during storage and transit. Such infections cause major postharvest losses and are considered a limiting factor in the storage and shipment of cut flowers (Carre, 1984; Cline and Bardsley, 1984; McCain and Welch, 1982). Low storage temperatures slow the development of B. cinerea infections (Maude, 1980), but do not always provide adequate control for long-term storage or when inoculum loads are high. At present, many rose growers dip cut flowers in fungicides to prevent postharvest development of B. cinerea infections, but this practice leaves unsightly residues on the flowers and foliage (McCain and Welch, 1982). Fungistatic atmospheres are used to control B. cinerea infec- tions on certain commodities during storage and shipment (Maude, 1980). The atmospheres can be applied in storage rooms or shipping containers and do not leave the unsightly residues as- sociated with most fungicide dip treatments. Carbon dioxide- enriched atmospheres are used to minimize Botrytis rot of straw- berry fruit during truck shipment (Harvey, 1982). Phillips et al. (1985) found that atmospheres containing 10% to 30% CO2 significantly reduced Botrytis flower rot of roses stored at 10 to 12C for 6 days, but Joyce and Reid (1986) reported foliar dam- age to 'Sonia' roses after storage for 7 days at 1C in CO 2 con- centrations as low as 7%. Sulfur dioxide-enriched atmospheres are used to control de- diluted to 1000/ml in deionized water, and sprayed onto the
Papillomavirus virus-like particles for the delivery of multiple cytotoxic T cell epitopes.

Chimeric papillomavirus (PV) virus-like particles (VLPs) based on the bovine papillomavirus type 1 (BPV-1) L1 protein were constructed by replacing the 23-carboxyl-terminal amino acids of the BPV1 major protein L1 with an artificial "polytope" minigene, containing known CTL epitopes of human PV16 E7 protein, HIV IIIB gp120 P18, Nef, and reverse transcriptase (RT) proteins, and an HPV16 E7 linear B epitope. The CTL epitopes were restricted by three different MHC class I alleles (H-2(b), H-2(d), HLA-A*0201). The chimeric L1 protein assembled into VLPs when expressed in SF-9 cells by recombinant baculovirus. After immunization of mice with polytope VLPs in the absence of adjuvant, serum antibodies were detected which reacted with both polytope VLPs and wild-type BPV1L1 VLPs, in addition to the HPV16E7 linear B cell epitope. CTL precursors specific for the HPV16 E7, HIV P18, and RT CTL epitopes were also detected in the spleen of immunized mice. Polytope VLPs can thus deliver multiple B and T epitopes as immunogens to the MHC class I and class II pathways, extending the utility of VLPs as self-adjuvanting immunogen delivery systems.
Abnormal processing of affective words by psychopaths.

We tested the hypothesis that psychopathy is associated with abnormal processing of affective verbal material. Criminal psychopaths and nonpsychopaths, defined by the Psychopathy Checklist, performed a lexical decision task ("Is it a word or not? ") while we recorded reaction time and event-related potentials in response to letter-strings consisting of affective and neutral words and pronounceable nonwords. On the assumption that they do not make efficient use of affective information, our primary prediction was that psychopaths would show less behavioral and event-related potential differentiation between affective and neutral words than would nonpsychopaths. The results were in accordance with this prediction. The lexical decisions of nonpsychopaths were significantly faster, and relevant event-related potential components were significantly larger, to affective words than to neutral words. In sharp contrast, psychopaths failed to show reaction time facilitation or larger amplitude event-related potentials to affective words. We suggest that psychopaths extract less information from affective words than do other individuals. Possible implications of these and related findings for understanding the behavior of psychopaths are discussed.
MULTIPLE MINOR MALFORMATIONS AS A MARKER FOR PRENATAL ETIOLOGY OF CEREBRAL PALSY

A consecutive series of 137 patients with cerebral palsy living in institutions and aged between 18 and 30 years was examined for minor malformations, using a modified Weighted Anomaly Score. After examination, the patients were divided into two groups, based on whether their cerebral palsy was prenatal or postnatal in onset. A further subset of prenatal‐onset patients with unidentified etiology was also analysed. Both the prenatal group with known etiology and the subgroup with unknown etiology had significantly more minor malformations than the postnatal group. These results suggest that multiple minor malformations may indicate prenatal etiology of cerebral palsy.
Functional characterization of five constitutively activating thyrotrophin receptor mutations

Gain of function mutations of the thyrotrophin receptor (TSHR) affect several functional characteristics, such as cAMP and inositol phosphate (IP) accumulation, cell surface expression and TSH affinity. In this study we compared five constitutively activating TSHR mutations, four receptors with a point mutation (S505N, L629F, I630L, V656F) and a nine amino acid (aa) deletion mutant (aa positions 613–621) for these functional parameters in parallel transfection experiments.
Selected atherosclerosis risk factors in youth aged 13-15 years .

INTRODUCTION The high frequency of cases of circulatory system conditions in Europe and other countries around the world requires scientific research to define risk factors of early atherosclerotic changes. The aim of the present study was to define which students are at danger of developing atherosclerosis by means of measuring cholesterol and triglyceride levels in blood as well as defining the correlation between atherosclerosis risk factors and arterial blood pressure, physical fitness and efficiency of the subjects. MATERIAL/METHODS The research covered 167 students of Public Junior High School 1 in Biala Podlaska aged 13-15 years. Accutrend GCT was employed to define the levels of total cholesterol and triglycerides in the screen test. Those students who were found to have increased values of biochemical parameters of capillary blood were subjected to additional blood tests aiming to define complete lipid profile of venous blood. The blood pressure in subjects was tested three times. The Moderate-to-Vigorous Physical Activity (MVPA) test, suggested by American authors, was employed to define physical activity in subjects. EUROFIT was employed to define physical efficiency. RESULTS Among the 167 subjects there were found 42 students (25.1%) whose lipid level in capillary blood proved to be increased. Full lipid profile tests proved that 16 students (9.6%) had increased blood lipid levels; those subjects constituted the risk group. Subjects in the risk group were characterized by lower levels of physical activity and physical efficiency compared to subjects with normal blood lipid level. Moreover, the frequency of hypertension was greater in risk group subjects compared to subjects with normal blood lipid levels. INFERENCES Students diagnosed with atherosclerosis risk factors require observation and early prophylactics by adopting habits of healthy physical activity.
Talagrand’s Inequality

At an archaeological site I saw fragments of precious vessels, well cleaned and groomed and oiled and spoiled. And beside it I saw a heap of discarded dust which wasn’t even good for thorns and thistles to grow on. I asked: What is this gray dust which has been pushed around and sifted and tortured and then thrown away? I answered in my heart: This dust is people like us, who during their lifetime lived separated from copper and gold and marble stones and all other precious things - and they remained so in death. We are this heap of dust, our bodies, our souls, all the words in our mouths, all hopes.
Vestibular Hypofunction in the Initial Postoperative Period After Surgical Treatment of Superior Semicircular Canal Dehiscence

Objectives: 1) Determine the prevalence of vestibular hypofunction in the immediate postoperative period after surgical treatment of superior semicircular canal dehiscence syndrome. 2) Evaluate whether dehiscence length is associated with risk of postoperative vestibular hypofunction. 3) Compare the prevalences of immediate and late postoperative vestibular hypofunction. Study Design: Clinical review. Setting: Tertiary referral center. Patients: Subjects with superior canal dehiscence syndrome (n = 42) based on history, physiologic testing, and computed tomography findings, who underwent middle fossa craniotomy and superior canal dehiscence plugging. Intervention: Dehiscence length was measured intraoperatively. Bedside horizontal head thrust testing (hHTT) was administered between postoperative days 1 to 7 to diagnose immediate postoperative vestibular hypofunction. Both hHTT and quantitative vestibulo-ocular reflex testing were administered 6 to 29 weeks postoperatively to detect late vestibular hypofunction. Main Outcome Measures: Dehiscence length and hypofunction in response to hHTT. Results: Thirty-eight percent of the subjects (95% confidence interval, 25-54) had hypofunction in response to hHTT within 1 week after surgery. Mean dehiscence lengths were 4.9 (range, 2.0-10.5 mm) and 3.4 mm (range, 1.0-5.5 mm) in subjects with and without postoperative hypofunction, respectively (p = 0.0018). Each 1-mm increase in dehiscence length increased the odds of immediate postoperative hypofunction 2.6-fold (95% confidence interval, 1.3-5.1). The prevalence of vestibular hypofunction was significantly higher in the early compared with the late postoperative period. Conclusion: Immediate postoperative vestibular hypofunction is common, particularly with larger dehiscences. This hypofunction may typically resolve, given that the prevalence of vestibular hypofunction 6 weeks postoperatively is low. Possible mechanisms include intraoperative loss of perilymph, which may be more likely with larger dehiscences.
4-Methoxybenzaldehyde (5-bromopyrimidin-2-yl)hydrazone monohydrate

In the title Schiff base compound, C12H11BrN4O·H2O, the organic molecule exists in an E configuration with respect to the C=N double bond. The pyrimidine ring is approximately planar, with a maximum deviation of 0.011 (2) Å, and forms a dihedral angle of 10.68 (8)° with the benzene ring. In the crystal, intermolecular O—H⋯N, N—H⋯O and C—H⋯O hydrogen bonds link the molecules into a two-dimensional network parallel to the ac plane.
Design and Specifications of the ITER TF Coils

The current design of the ITER Toroidal Field coils and structures, the main critical design and manufacturing issues, and the status of the procurement arrangements for these components, which will be released to the ITER parties in early 2008 to start the manufacturing contracts, are described. Some qualification and R&D work still required in preparation for the manufacture are also mentioned.
Contact Lens Fitting for Keratoconus After Intacs Placement

Purpose. To describe a patient with keratoconus who underwent Intacs surgery to one eye with an unsatisfactory result and refused to undergo an Intacs removal procedure. Methods. Case report. Results. The patient’s eye was fitted with a soft contact lens for visual rehabilitation 5 months after Intacs placement. Conclusions. Intacs, with the help of secondary refractive procedures or contact lenses, may still be considered as effective in postponing penetrating keratoplasty, even in patients with advanced keratoconus.
Multifrequency studies of the narrow-line Seyfert 1 galaxy SBS 0846+513

The narrow-line Seyfert 1 galaxy SBS0846+513 was first detected by the Large Area Telescope (LAT) on-board Fermi in 2011 June–July when it underwent a period of flaring activity. Since then, as Fermi continues to accumulate data on this source, its flux has been monitored on a daily basis. Two further γ-ray flaring episodes from SBS0846+513 were observed in 2012 May and August, reaching a daily peak flux integrated above 100 MeV of (50±12)×10 8 ph cm 2 s 1 , and (73±14)×10 8 ph cm 2 s 1 on May 24 and August 7, respectively. Three outbursts were detected at 15 GHz
DBA/2J (Mls‐1a) B‐cell differentiation in BALB.xid recipients

Studies of superantigens (SAg) have focused primarily on their impact on CD4+ T cells, largely bypassing the impact of the sequelae of this interaction upon the antigen‐presenting cell (APC). Sequelae of SAg‐induced CD4+ T‐cell activation include the ‘bathing’ of the SAg‐presenting cell with cytokines that promote the differentiation of the APC. In this report, the SAg‐induced differentiation of Mls+ DBA/2J B cells was studied in vivo by their transplantation into B‐cell‐defective BALB.xid recipients. Rapid, high‐level serum immunoglobulin M (IgM) production was noted shortly after transfer, disappearing by 3 weeks. Donor B cells, as evidenced after their chemical and genetic impairment and by the use of an IgM allotype‐disparate donor–recipient combination, contributed to this transient IgM production. These results clarify a discrepancy in the literature regarding donor B‐cell contribution to IgM production and illustrate a model system to utilize SAg to study B‐lymphocyte diversity.
Syndecan-1 Acts in Synergy with Tight Junction Through Stat3 Signaling to Maintain Intestinal Mucosal Barrier and Prevent Bacterial Translocation

Background:Intestinal epithelial tight junction (TJ) is the principal determinant of mucosal permeability, defects of which have been correlated to inflammatory bowel disease. In this study, we investigated whether syndecan-1 (Sdc1), the predominant cell surface heparan sulfate proteoglycan, affects TJ proteins to protect intestinal barrier function. Methods:The role of Sdc1 in barrier function was examined in cultured colonic epithelial cells and dextran sodium sulfate–induced colitis mouse model. Barrier function was determined by transepithelial electrical resistance, bacterial translocation, and FITC-dextran flux. Canonical TJ proteins ZO-1 and occludin were measured by Western blot and immunofluoresence. Role of the Stat3 pathway was detected by Western blot and chromatin immunoprecipitation. Results:Overexpressed Sdc1 in Caco-2 cells attenuated transepithelial electrical resistance reduction, prevented bacterial translocation, and repressed FITC-dextran flux, whereas Sdc1 knockdown in HT29 cells resulted in a greater loss of barrier function. Supplementation of exogenous Sdc1 in colitis mice ameliorated the activity of colitis and barrier defect. Mechanistically, Sdc1 significantly modulated expressions of ZO-1 and occludin by activating Stat3, which directly bound to the promoter regions of ZO-1 and occludin. Furthermore, ZO-1 and occludin were found to bind to each other, and their repression could induce Sdc1 upregulation. Conclusions:Sdc1 plays an important role in protecting the intestinal barrier function and preventing bacterial translocation, in synergy with TJ through Stat3 signaling in an Sdc1/Stat3/ZO-1 and occludin feedback loop. Sdc1 participates in the mechanism that is related to intestinal barrier function and colitis and represents a therapeutic target for novel anti-inflammatory bowel disease strategies.
Dopamine vs Noradrenaline: Inverted-U Effects and ADHD Theories

The aim of the present study was to review the dopamine theory of attention-deficit–hyperactivity disorder (ADHD), in light of recent use of noradrenergic therapies. A historical review of pharmacological theories of ADHD was conducted, including inverted-U, spatial working memory and neural circuit aspects. Pharmacological advances, including animal and human studies of dopaminergic and noradrenergic mechanisms at the prefrontal cortex (PFC), indicate that α-2A adrenoreceptor stimulation results in increased dendritic firing during delay periods for preferred directions, while moderate levels of D1 receptor stimulation result in reduction of delay-related firing to non-preferred directions, allowing representational control in the PFC. Recent studies of the COMT val/met gene and stimulant medication response may help explain variation in inverted-U responses in individuals. Further studies utilizing delay-related firing paradigms should be useful in the investigation of attentional syndromes, and responses to newer pharmacological treatments.