Miracle-dz/UniFAR-FTUs huggingface dataset:
Partners’ Similarity in Differentiation of Self is Associated With Higher Sexual Desire: A Quantitative Dyadic Study

The relationship between sexual desire and differentiation of self in couples has been frequently discussed in clinical literature but lacks empirical support. This exploratory study investigates the associations between individual and dyadic levels of sexual desire, differentiation of self, and couple satisfaction. Similarities and discrepancies in sexual desire and differentiation of self between partners were especially targeted. Partners were expected to have a lower discrepancy of differentiation of self than unrelated individuals (Bowen's similarity hypothesis). Partners’ discrepancy in differentiation of self was expected to be negatively associated with sexual desire, and higher levels of sexual desire and differentiation in the dyad were expected be positively associated with couple satisfaction. Results suggest that partners’ similarity regarding differentiation of self predicted individual sexual desire. Other findings suggest that couple satisfaction was positively associated with both sexual desire and differentiation of self. Limitations and clinical implications are discussed.
From Human Papillomavirus to Cervical Cancer

C cancer is one of the most common female malignancies worldwide; 80% of cases occur in low-resource regions.1,2 Screening programs have been very successful in the United States, Europe, and other regions able to achieve broad and sustained coverage. In the United States, the disease is controlled at an annual cost of billions of dollars representing a major commitment by patients and clinicians. In fact, cervical cancer screening and management of minor screening abnormalities are among the most time-consuming parts of some gynecology practices. Cervical cancer prevention can now be made even better. Substantial modifications of practice are forthcoming, motivated by improved understanding of human papillomavirus (HPV) natural history and cervical carcinogenesis. In this update, we will summarize the new knowledge and its possible implications in the United States.
Ependymoma with “granular cell” features: Report of two cases

We report two cases of ependymoma which showed prominent “granular cell” changes of the cytoplasm. The patients were a 7‐year‐old boy with a tumor in the cerebellum (case 1) and a 70‐year‐old man with a tumor in the frontal lobe (case 2). The tumor of case 1 showed a histopathological appearance of ependymoma containing many focal aggregates of large polygonal cells in which the cytoplasm was stuffed with numerous eosinophilic granules. The tumor of case 2 predominantly showed the features of papillary ependymoma, and some tumor cells were swollen and contained similar eosinophilic granules. Intracytoplasmic granules in both tumors were immunoreactive for GFAP and ubiquitin, but not for epithelial membrane antigen, CD68 or mitochondria. Ultrastructurally, they were found as aggregates of membrane‐bound, electron‐dense, globular structures. Karyotypic analysis of the tumor in case 1 demonstrated 2, 11 and 12 trisomies. Intracytoplasmic eosinophilic granules occasionally occur in astrocytic and oligodendroglial neoplasms, but an appearance of similar granules is very rare in ependymoma. The two cases presented here may represent a new histopathological variant of ependymoma, and the term “granular cell ependymoma” is appropriate for them.
The Effect of Surgeon Volume on Outcomes and Resource Use for Vaginal Hysterectomy

OBJECTIVE: To estimate the effect of surgical volume on outcomes and resource use in women undergoing vaginal hysterectomy. METHODS: Women who underwent total vaginal hysterectomy and were registered in the Perspective database were examined. Perspective is a nationwide database developed to measure quality and resource use. Procedure-associated intraoperative, perioperative, and postoperative medical complications as well as hospital readmission, length of stay, intensive care unit (ICU) use, operating time, and cost were analyzed. Based on the overall gynecologic surgical volume and vaginal surgical volume of their surgeons, patients were stratified into tertiles. Complications were compared using adjusted generalized estimating equations and reported as odds ratios (ORs). RESULTS: A total of 77,109 patients operated on by 6,195 gynecologic surgeons were identified. After adjustment for the effects of other demographic variables and concomitant procedures, patients operated on by high-volume vaginal surgeons were 31% (OR 0.69; 95% confidence interval [CI] 0.59–0.80) less likely to experience an operative injury, whereas perioperative complications were reduced by 19% (OR 0.81; 95% CI 0.72–0.92), medical complications decreased by 24% (OR 0.76; 95% CI 0.67–0.86), ICU admission reduced by 46% (OR 0.56; 95% CI 0.43–0.73), and the transfusion rate decreased by 28% (OR 0.72; 95% CI 0.61–0.85) in patients treated by high-volume vaginal surgeons, whereas rates of readmission were higher (OR 1.24; 95% CI 1.04–1.47) in patients treated by high-volume surgeons. Operative times were lower in patients operated on by high-volume surgeons (P<.001). Although total gynecologic surgical volume had no effect on cost, patients treated by high-volume vaginal surgeons had lower costs (P<.001). CONCLUSION: Perioperative morbidity and resource use are lower in women undergoing vaginal hysterectomy when the procedure is performed by high-volume vaginal surgeons. LEVEL OF EVIDENCE: II
Protective effect of paraoxonase 1 of high‐density lipoprotein in type 2 diabetic patients with nephropathy

Aim: Paraoxonase 1 (PON1) is an important antioxidative enzyme associated with high‐density lipoproteins (HDL). Recent data suggest that HDL antioxidative ability may be altered in type 2 diabetic patients. The aim of this study was, therefore, to investigate whether HDL‐PON1 activity and HDL antioxidative ability were related to the presence and severity of diabetic nephropathy.
Impact of Drug Abuse Treatment Modalities on Adherence to ART/HAART Among a Cohort of HIV Seropositive Women

Methadone maintenance is associated with improved adherence to antiretroviral therapies among HIV-positive illicit drug users; however, little information exists on whether adherence is associated with different drug abuse treatment modalities. Using longitudinal data from the Women's Interagency HIV Study, we evaluated the relationship between drug abuse treatment modality and adherence to antiretroviral therapies. In prospective analyses, individuals who reported accessing any drug abuse treatment program were more likely to report adherence to antiretroviral regimens ≥ 95% of the time (AOR = 1.39, 95% CI = 1.01–1.92). Involvement in either a medication-based or medication-free program was similarly associated with improved adherence. Drug abuse treatment programs, irrespective of modality, are associated with improved adherence to antiretroviral therapies among drug users. Concerted efforts to enroll individuals with drug use histories in treatment programs are warranted to improve HIV disease outcomes.
Effect of Opium Addiction on Diabetes

Background: Type 2 diabetes is a common disorder that is recognized as a major health problem in Iran. Diabetes is a major cause of morbidity, mortality, and economic burden to the society. Some people believe that smoking opium can reduce serum glucose and lipids in diabetes mellitus. This study was designed to compare blood glucose and lipids in opium addicts with non-addicts among patients with type 2 diabetes. Methods: In this case, control study subjects were chosen from type 2 diabetic patients. Twenty-three males with type 2 diabetes and addicted to opium were selected as the case group, and 46 patients with no addiction to opioid drugs were chosen as control group. Blood Sugar (BS), glycated hemoglobin (HbA1C), lipids and microalbumin in urine were measured in two groups. Results: Our results showed that the mean FBS and 2-hour post prandial were significantly different between two groups. (P =. 04). No significant difference was observed in HbA1C, triglyceride, total cholesterol, LDL, and HDL between the two groups (P >. 05). Conclusions: Our finding showed that while opium might decrease blood glucose temporarily, it had no clear and long-lasting effects on blood glucose, as it had no significant effect on HbA1c.
Length of hospital stay and the timing of ECT

The lengths of stay of patients receiving ECT and medication or medication alone on an acute elderly admission ward were retrospectively compared. The lengths of stay for those who received ECT were significantly longer than for those not receiving ECT. If the ECT was given within 4 weeks of admission, the length of stay was similar to those receiving medication alone. In addition to symptom complexes, the decision to use ECT should take into account the length of the illness. Early ECT may reduce lengths of stay and decrease the likelihood of chronicity.
Role of the VEGF 936 C/T polymorphism in diabetic microvascular complications in type 2 diabetic patients

Aim: Vascular endothelial growth factor (VEGF) is important in the pathogenesis of diabetic microvascular complications and the genetic polymorphism of this gene may contribute to the development and progression of diabetic microvascular complications. In this study, we investigated whether a genetic polymorphism of VEGF is associated with diabetic complications.
Who Wants to be a Surgeon? A Survey of Medical Students at the University of Nairobi, Kenya

Background: In Sub Saharan Africa, surgical conditions account for a significant disease burden. Surgical workforce is however inadequate, and thus strategies such as attracting medical students to surgical specialties could avert the situation. This study determined the proportion of students interested in pursuing surgical career and factors that influence choice of this specialty. Methodology Four hundred and fifty medical students, from first to fifth year of study at the University of Nairobi, were each issued a self administered questionnaire designed to assess their specialty preferences, and factors influencing these choices. Results: The response rate was 385/450(85.6%). Surgery was the most popular specialty with 105(27.3%) students. Majority, 6 (57%), of those who preferred surgery were in the preclinical years. Male students had a two-fold likelihood of selecting a surgical career compared to females. Significant factors that attracted students to surgery instead of non surgical careers were prestige of the specialty (p<0.001), presence of a role model (p=0.002), and intellectual challenge (p=0.005). Main deterring factors were ease of raising a family (p<0.001), length of residency (p<0.001) and lifestyle of practice (p=0.020). Conclusion: Although surgery is the most preferred specialty among medical students at the University of Nairobi, there appears to be a declining interest among the clinical students. In order to attract and maintain student interest in the specialty, there is need for early and active mentoring. The Annals of African Surgery, Volume 6, 2010
Urine and Plasma Pharmacokinetics of Lofexidine after Oral Delivery in Opiate-Dependent Patients

Objectives: The objective of this study was to investigate lofexidine urine and plasma pharmacokinetics using three different dosing regimens in opioid dependent subjects. To date, there have been no published studies on lofexidine appearance and excretion in urine of opioid dependent subjects. Methods: Subjects were stabilized with 100 mg morphine sulphate on days 3–8 of the study. The dosing regimens of lofexidine hydrochloride were . 8 mg twice a day (BID), 1.2 mg BID, or . 8 mg three times a day (TID) on days 9 through 16 of the study. Plasma and urine samples were collected at appropriate time points. Area under the concentration-time curve (AUC), maximum concentration in plasma (Cmax), time when maximum concentration was reached (Tmax) and fraction excreted unchanged in urine (Fe) were calculated. Results: The average half-life obtained from all profiles was 12.1 ± 6.3 hr. Steady-state (SS) was reached by study day 15. The plasma pharmacokinetic parameters for 1.2 mg BID and . 8 mg TID dosing regimens did not seem to be different at steady state (day 15). Tmax was not statistically significantly different across dosing regimens. Fe values ranged between . 01% and 34% with high variability within the same dosing regimen. For the total dose of 2.4 mg/day the two dosing regimens that were evaluated, namely 1.2 mg BID and . 8 mg TID, did not show a significant statistical difference in plasma and urine pharmacokinetic parameters. Conclusion: Although preliminary due to the limited number of subjects, these findings are the first to document lofexidine urine pharmacokinetics in opiate addicts using a highly sensitive liquid chromatography tandem mass spectrometric analysis.
PERISTALSIS IN A LOOP OF SMALL INTESTINE: A DIRECT STUDY

Knowledge of the movements of the small intestine has been obtained by various methods. The chief methods of study have been roentgenograms or fluoroscopy following an opaque meal; direct observation, after opening the abdomen of an animal submerged in a bath of physiologic sodium chloride solution at body temperature; observation of the changes in pressure produced in a thin walled rubber balloon inserted in the lumen of the intestine, and direct observation of excised intestine, kept alive in an oxygenated saline bath at body temperature. This study is the direct observation of peristaltic movements in a loop of small intestine which was always present in an unusual congenital umbilical hernia of an old negro. The first observation at once impressed us that the case offered an unusual opportunity because the movements were so plainly seen. The hernia was in the midline of the abdomen immediately above and continuous with the
The attitudes of dental interns to the use of the rubber dam at Riyadh dental colleges

Background : The rubber dam is one of the best tools for tooth isolation and infection control in the dental field. Our aim is to evaluate the attitudes toward the use of rubber dams by dental interns in Riyadh Dental Colleges (RCsDP) and determine the barriers to their use. Materials and Methods: A self-administered questionnaire was designed and used for data collection. 150 questionnaires were distributed by hand to the dental interns of RCsDP over a period of two weeks. Information sought included the attitudes toward and difficulties for the use of the rubber dam, the time needed to apply the rubber dam, and the patients' allergic history of the rubber dam. Respondents were asked to state their preference on a five point Likert type scale ranging from strongly dislike to strongly like. The information and data of the completed questionnaires were statistically analyzed using Mann-Whitney U test and Friedman test. Results: Of 150 questionnaires distributed, 150 were completed and returned (response rate = 100%). Of those, 46.7% were males and 53.3% were females. In general; (43.3%), interns strongly liked the use of the rubber dam and the rest (46.7%) liked the use of the rubber dam. The majority of respondents liked to use rubber dam in direct restorations more than in indirect restorations and 46.7% strongly liked to use it in posterior teeth for composite restoration. Most dental interns felt that they would strongly like to use a rubber dam for endodontic treatment whether in posterior teeth (73.3%) or anterior teeth (68.7%). 66.7% of interns asked their patients if they had an allergy to latex prior to the use of the rubber dam. Child behavior (mean rank about seven) is the most important reason for not using rubber dam. The time is taken to apply the rubber dam was less than five minutes in most cases. Conclusion: Most dental interns prefer to use rubber dams in the general dental field and are enthusiastic to use it in future.
Body composition, dietary salt and sugar intake as determinants of breast cancer: a case-control study

Treatment involves multiple aspects such as physical, psycho-logical, social, cultural, spiritual and economic. A holistic view of the patient and a multidisciplinary approach are mandatory. A healthylifestyle plays an important role in the prevention of this type of cancer.The aim of this study was to identify the dietary and body composition determinants of breast cancer among menopausal and healthypatients A total of ninety three menopausal women were included in the study and were divided in two groups: without cancer (G1; n 61)and with breast cancer (G2; n 32). All individuals in both groups had their clinical, metabolic and dietetic proÞles examined. StudentOst-test and MannÐWhitney test were used in the statistical analysis. The CI was set at 95% and signiÞcance level at 5% ( P < 0.05). Patientsin G2 were older than G1 (mean 59 (
Late onset Pneumocystis pneumonia in patients receiving rituximab for humoral renal transplant rejection

Rituximab has been used increasingly in the treatment of antibody‐mediated rejection (AbMR) in solid organ transplantation despite the absence of clinical trials demonstrating efficacy. A contributor to the growing use of rituximab is an apparent lack of morbidity; and there are no reports of specific opportunistic infections associated with its use in renal transplant recipients. Two cases of Pneumocystis pneumonia (PCP) occurring nearly 3 years after administration of rituximab for refractory AbMR are reported herein. These cases emphasize the need for ongoing vigilant observation in patients who have received rituximab, and highlight the importance of clinical trials to establish the role of rituximab in prevention and treatment of AbMR.
Integration of Medical and Psychological Treatment within the Primary Health Care Setting

ABSTRACT Integrated care entails the provision of behavioral health services within the primary care setting and emphasizes a collaborative approach between mental health professionals and primary care providers (Kenkel, Deleon, Orabona Mantell, Steep, 2005). Research was collected to highlight the history, development, and implementation of integrated care within primary care facilities. The authors performed a comprehensive literature review of collaborative care and summarized the program design of the site where they work. It is hypothesized that integration will improve patient access to health care, increase the rate of evidence based practice, improve patient health and satisfaction, and reduce long-term costs.
Quality assurance in radiographic reporting: a proposed framework

Abstract Radiographers are becoming increasingly involved in the interpretation of images like accident and emergency (A&E) plain films due to the relaxing of restrictions on who can report. Any systematic approach to changing radiographers professional practice and long-held patterns of behaviour should include plans to monitor and evaluate, and to maintain and reinforce any change. A central theme of current U.K. health policy is quality. Therefore, the successful implementation of radiographers in a reporting role requires their performance to be monitored during clinical audit to assure quality in clinical practice. To meet this challenge a framework is proposed for assuring the quality of radiographic reporting underpinned by the scientific method and audit cycle. These principles can be applied to other role development initiatives.
Clinical findings and progression of 10 cases of equine ulcerative keratomycosis (2004–2007)

Summary Ulcerative keratomycosis is a serious sight-threatening disease of horses and the veterinary literature is replete with cases of poor visual outcome following this condition. During a 3 year period, 10 horses were treated for confirmed keratomycosis at the Veterinary Teaching Hospital (VTH) of the University of Cordoba (Spain). Ulcerative keratomycosis accounted for an average of 8.62% of the total equine ophthalmic admissions during this time and an average of 33.3% of horses were diagnosed with infectious keratitis. Fungi were diagnosed using cytology (n = 4) and/or culture (n = 8) and histopathology (n = 1). Aspergillus sp. was the most commonly isolated fungus. Medical therapy alone or combined medical and surgical treatment was utilised for therapy depending on the clinical condition. Miconazole 1% was the most common topical antifungal therapy employed. Median duration of treatment was 73.12 days. Records were evaluated to determine visual outcome and globe survival.
Measuring Satisfaction with Social Work Services

For various reasons, the role of the medical social worker is often unclear to persons seeking medical treatment. Allied health professionals, such as nursing staff, tend to have a better understanding of the medical social worker's role and of whether services are being provided to best meet each patient's needs. We aimed to illustrate the abilities of nursing staff to provide patient satisfaction feedback to medical social workers in such areas as responsiveness to patient requests and the satisfaction of patients and their family members with the social services provided. Use of this satisfaction measurement technique will hopefully resolve any confusion that patients, and others not familiar with the role of the medical social worker, may have. This method provides accurate measurement of patients' evaluation of medical social work services.
Opinions on the content and effects of the Caring for Australasians with Renal Impairment (CARI) Guidelines: A survey of renal nurses and comparison with the opinions of nephrologists in Australasia

Aim: Renal nurses in Australia and New Zealand are critical to the care of patients with chronic kidney disease (CKD), especially those on dialysis. We aimed to obtain the opinions of renal nurses in Australia and New Zealand on the Caring for Australasians with Renal Impairment (CARI) Guidelines.
Does Sex Affect the Muscle Strength and Regional Lean Tissue Mass Response to Resistance Training in Older Adults

This study examined if the adaptation in muscle strength and whole body and regional lean tissue mass (LM) differs in older men (M) and women (W) subsequent to a program of high-intensity resistance exercise. Ten men and six women aged 65-78 yr underwent 20 weeks of training, twice per week, for 3 sets of 8RM for 7 upper and lower body exercises. Dynamic muscle strength was determined by 1-RM and isometric knee extensor strength by dynamometry. Lean tissue mass was determined by dual energy X-ray absorptiometry. Following training, men and women exhibited significant (p<0.001) though similar increases in dynamic upper (women, 28.9±11.7%; men, 32.0±11.1%; mean±SD) and lower (W, 38.4±14.7%; M 30.3±11.7%) body strength, and isometric knee extensor strength. There was a significant time effect (p<0.001) for whole body LM (W, 0.85±0.83 kg; M, 0.70±0.70 kg), upper limb LM (W, 0.21±0.16 kg; M, 0.25±0.13 kg), lower limb LM (W, 0.38±0.42 kg; M, 0.27±0.41 kg) and trunk LM (W, 0.25±0.38 kg; M 0.18±0.34 kg), with no interaction (p=0.58-0.78). These results suggest that well-functioning older men and women show similar gains in muscle strength and whole body and regional lean tissue mass indicating comparable neuromuscular and anabolic responses accompanying resistance training.
Adults with Acquired Traumatic Brain Injury: Experiences of a Changeover Process and Consequences in Everyday Life

The purpose of this study is to illuminate the changeover process, support, and consequences experienced by adults who acquired traumatic brain injury (TBI). Fifteen persons were in-depth interviewed using a semi-structured interview guide. Data were analyzed by latent-content analysis and structured into six themes. Consequences were negative as well as positive. Significant others were important as a driving force for training and life-situation. The informants were initially satisfied with social supports but in the longer term became more critical regarding accessibility to such supports. The majority had difficulties in returning to working life after injury. The outcomes seemed to be a prolonged process, probably never-ending, which gradually became integrated as a part of life.