Miracle-dz/UniFAR-FTUs huggingface dataset:
Approaching “sensitive” topics: criticality and permissibility in research-led teaching about children, sexualities, and schooling

ABSTRACT This paper considers the feasibility and desirability of radical, critical pedagogies in teaching higher education students about “sensitive” topics with children, sexualities, and schooling used as an example to explore this. Reflecting on early career research-led teaching, I confront anxieties informing decisions about what and how to teach children’s geographies of sexualities in light of student and institutional expectations and evaluations, and in relation to how colleagues have taught. Scrutinising my pedagogy with respect to what could have been more evocative teaching and uncomfortable learning, I question the extent to which I achieved the radical and critical potential I foresaw in introducing teaching on children and sexualities; teaching which – alongside student and institutional expectations and evaluations – has been informed through broader social norms of acceptability and permissibility, and contemporary imperatives for knowledge to be “relevant” and “useful”. In gesturing toward more challenging teaching, I consider the appropriateness of trigger/content “warnings” and explore speakability (after Monk) as a strategy for approaching “sensitive” topics, including age of consent. As an alternative to trigger/content warnings, I explore principles of content previews/ forecasts when broaching “sensitive” topics while remaining critical of what constitutes “sensitive” topics/content throughout.
THE EFFECT OF INTERACTION VIA SOCIAL MEDIA AND PAST ONLINE SHOPPING EXPERIENCE ON REPURCHASE INTENTION THROUGH TRUST IN TOKOPEDIA APPLICATION USERS IN SURABAYA

This research aims to analyze the effect of interaction via social media and past online shopping experience on repurchase intention through trust in Tokopedia application users in Surabaya. Today, online purchasing through e-commerce is in vogue. Before making a purchase, most people will seek information first to increase their trust, and they can do this by interacting with others. Increasingly sophisticated technology makes this interaction easy because there is already social media. The information shared by someone certainly comes from their experience. E-commerce consumer interact through social media and consumer shopping experience are important points so that consumers can increasingly trust e-commerce and repurchase it in e-commerce. This research is designed in quantitative approach with purposive sampling as the sampling technique. The sample used in this research was 150 respondents. The requirements of respondents in this research were at least 17 years old who had made purchases at Tokopedia at least once in the last two months in Surabaya. Data was collected using a questionnaire. The data analysis technique used is SEM analysis with the LISREL program. The results of the research prove that interaction via social media and the past online shopping experience have a significant effect on trust. Trusts have a significant effect on repurchase intention. Interaction via social media and past online shopping experience has a significant effect on repurchase intention through trust.
The perspectives of teachers in Catholic schools on how to develop sustainable learning communities

The move from an industrial society to a knowledge society has given rise to an increased awareness of the importance of learning, the knowledge and understanding that people gain through the learning process and the learning environment in which that learning occurs. The nature of how people learn, and the context in which learning occurs, have changed significantly in recent years, yet the learning environment of schools has changed very little which suggests that it needs to reflect current knowledge about learning. There is a recognition that learning does not occur in isolation, but that individuals are part of a community of learners, and that learning with any community is based on a set of values that gives meaning to the learning and can lead to the development of sustainable learning communities. All of this, however, is dependent on the understanding of key figures in the learning process which are the teachers; it is teachers who have the ability to change the way in which learning occurs in schools (Sergiovanni, 1996). The purpose of this study is to gain an understanding of teachers' perspectives on the learning environment and how that learning environment can be organised to enhance the learning process. The context for this study is the Catholic Education System in Western Australia; specifically, two secondary colleges that operate within this system. Catholic schools have been selected because they have a clearly defined set of values, a common culture, and a focus on building community which form the basis on which the learning environment is established. It was the nature of the study that determined the adoption of a qualitative research methodology, and suggested an interpretive theoretical approach to the research question concerning teachers' perspectives on their learning environment. A grounded theory
Perceived Discrimination, Ethnic Identity, and Mental Distress Among Asian International Students in Korea

This study explored the associations between perceived discrimination, ethnic identity, and mental distress among 118 Asian international college students in Korea. Perceived discrimination and ethnic identity were included as critical factors in international students’ adaptation to living in Korea, and their associations with self-report measures of depression and anxiety were explored using canonical correlation and latent profile analysis. Based on studies identifying two types of discrimination, we explored how each discrimination type relates to mental distress. Results indicated (a) students’ perceptions of personal rejection (i.e., demeaning and overt acts of discrimination) were significantly associated with depression and anxiety, and this association was stronger than that of perceived unfair treatment, and depression and anxiety (b) students’ exploration of ethnic identity had a positive relationship with anxiety. These results suggest the need to provide additional supports for international students engaged in the exploration process. The current results also suggest that Asian international students’ adaptation experiences in Korea may differ from those international students in other countries as reported in the literature. More attention and study with international students is needed to seek possible common parameters of adaptation in diverse cultural contexts of host countries.
Fiscal Policy, Consumption Risk, and Stock Returns: Evidence from U.S. States

We find that consumption risk is lower in states that implement counter-cyclical fiscal policies. Moreover, firms whose investor base are concentrated in counter-cyclical states have lower stock returns, along with firms that relocate their headquarters to a counter-cyclical state. Therefore, counter-cyclical fiscal policies lower the consumption risk of investors and consequently their required equity return premium. This conclusion is confirmed by smaller declines in market participation during recessions in counter-cyclical states. Overall, the location of a firm's investor base enables state-level fiscal policy to influence stock returns.
Comparing the Effects of Physical, Cognitive and Combined Rehabilitation on the Improvement of Working Memory and Cognitive Flexibility of the Elderlyy

The present study aimed to compare the effects of physical, cognitive and combined rehabilitation on improving working memory and cognitive flexibility of the elderly living in the nursing home. This quasi-experimental study was carried out with a pretest-posttest design in four groups with the control group. The statistical population consisted of all elderly residents of a nursing home in Tehran. 48 people were selected randomly and divided into four groups (three experimental groups and one control group). For the experimental groups, intervention programs, including physical, cognitive, and combined rehabilitation, were conducted in three sessions of one hour each week for two months. The data were collected using a working memory capacity scale and a cognitive flexibility inventory (CFI). Data was analyzed using a one-way analysis of covariance (ANCOVA) and Bonferroni post hoc test using SPSS software version 22. The results showed that all three types of rehabilitation programs have a significant effect on improving the working memory and cognitive flexibility of the elderly (P 0.001) According to the findings, combined rehabilitation programs can be effective in improving the working memory and cognitive flexibility due to the focus on both physical and cognitive aspects.
Uma análise de gênero a partir de dados da Sociedade Brasileira de Computação

A Sociedade Brasileira de Computação (SBC) é uma sociedade científica que reúne estudantes, professores, pesquisadores, profissionais e entusiastas da área de Computação do Brasil. Por se tratar da principal instituição civil que representa a área no país, este artigo tem como objetivo realizar uma análise quantitativa a partir dos dados das pessoas associadas à SBC, segundo gênero, localização, categoria de associação e áreas de interesse na Computação, a fim de traçar um panorama atual da Computação no país.
Self-reassurance, Self-criticism, and Eye-tracking of Happy Faces

This study explores the relationship between self-criticism, self-reassurance, and the face scan- ning patterns participants use to recognize photos of happiness. Forty-two participants were being recorded by eye-trackers while watching photos of happy and neutral facial expressions. Participants also completed the Forms of Self-Criticising/Attacking and Self-Reassuring Scale. The Hated Self score was negatively related to the total fixation duration on the eyes and around the eyes. The Inadequate Self score tended to correlate positively with the total fixation duration time on all examined areas of the face and Reassured Self score tended to correlate positively with the total fixation duration time on the area around the eyes, although none of these correlations appeared to be statistically significant. Being able to distinguish between the more pathological Hated Self form of self-criticism and the less pathological Inadequate Self could improve psychological assessment and intervention evaluations.
Elderly Self Acceptance Based on Gender and Residence and Its Implications to the Guidance and Counseling Services

This study was conducted based on the lamentations of the old people about the existence of themselves. The old people cannot accept their changes both physical and psychological.This study aims to describe the self-acceptance of the elderly in terms of gender and place of residence. The study sample consisted of 116 elderly people, 67 elderly people who lived at home and 49 elderly people who lived in the Affectionate Home of Mother Batusangkar. The instrument used is the elderly self-acceptance questionnaire with reliability of 0.840. The results of this study are the self-acceptance of the elderly differs significantly in terms of gender and place of residence and there is an interaction between sex and residence in explaining the self-acceptance of the elderly.
Alcohol Use Disorder and Antisocial and Borderline Personality Disorders

Alcohol use disorder (AUD) frequently co-occurs with other psychiatric disorders, including personality disorders, which are pervasive, persistent, and impairing. Personality disorders are associated with myriad serious outcomes, have a high degree of co-occurrence with substance use disorders, including AUD, and incur significant health care costs. This literature review focuses on co-occurring AUD and personality disorders characterized by impulsivity and affective dysregulation, specifically antisocial personality disorders and borderline personality disorders. Prevalence rates, potential explanations and causal models of co-occurrence, prognoses, and the status of existing treatment research are summarized. Several important future research considerations are relevant to these complex, co-occurring conditions. Research assessing mechanisms responsible for co-occurring AUD and antisocial personality disorder or borderline personality disorder will further delineate the underlying developmental processes and improve understanding of onset and courses. In addition, increased focus on the efficacy and effectiveness of treatments targeting underlying traits or common factors in these disorders will inform future prevention and treatment efforts, as interventions targeting these co-occurring conditions have relatively little empirical support.
Protective Effect of the Traditional Chinese Patent Medicine Qing‐Xuan Granule against Bleomycin‐Induced Pulmonary Fibrosis in Mice

Pulmonary fibrosis (PF) is a chronic obstructive pulmonary disease without effective clinical drug treatment. Qing‐Xuan Granule (QX) as a traditional Chinese patent medicine is clinically used to cure children's cough. This study was designed to investigate the effects of QX and possible molecular mechanisms for bleomycin‐induced PF. The work used Western blotting and Q‐PCR to explore the vitro and vivo mechanisms of QX treatment, while using HPLC‐TOF/MS to explore the composition of QX. QX was given daily orally for two weeks after bleomycin intratracheal instillation. The protective effects of QX on lung function, inflammation, growth factors, hydroxyproline content and deposition of extracellular matrix were investigated. QX decreased expression of Col I and α‐SMA in lung tissues by down‐regulating TGF‐β1‐Smad2/3 signaling and suppressed epithelial‐mesenchymal transition and effectively reversed abnormal mRNA levels of MMP‐1and TIMP‐1 as well as LOXL‐2 in lung tissues. HPLC‐TOF/MS indicate that six substances could be the main active components, which were reported to protect against experimental lung disease.
Suicidal ideation in patients with cancer: A systematic review of prevalence, risk factors, intervention and assessment

Abstract Objectives Suicidal ideation (SI) underlies risk of death by suicide. It is well established that patients with cancer are at increased risk of death by suicide. Therefore, understanding SI in patients with cancer is critically important. The goal of this systematic review was to investigate the prevalence, risk factors, intervention, and assessment of SI in patients with cancer. Methods This systematic review was registered with the PROSPERO database (CRD42018115405) and was guided by the PRISMA statement. We searched Medline, PsycInfo, Embase, CINAHL, the Cochrane Database of Systematic Reviews, and Cochrane Central. Two reviewers independently screened abstracts and assessed for quality assurance using a revised Newcastle-Ottawa Scale. Results We identified 439 studies to screen for eligibility. Eligible studies included adults with cancer diagnoses and listed SI as an outcome. Ultimately, 44 studies were included in the analyses. Prevalence of SI ranged greatly from 0.7% to 46.3%. Single items drawn from validated measures were the most frequent method of assessing SI (n = 20, 45.5%); additional methods included validated measures and psychological interviews. Commonly identified risk factors for SI included age, sex, and disease/treatment-related characteristics, as well as psychological constructs including depression, anxiety, hopelessness, existential distress, and social support. Significance of Results Assessment of SI in patients with cancer is the concern of researchers worldwide. Prevalence of SI varied with study population and was likely influenced by the method of assessment. Psychological distress consistently predicted SI. Increasing awareness of demographic, clinical, and psychological associations is critical for risk assessment and intervention development.
Teachers’ Perceptions of Adopting Information and Communication Technologies in Teaching and Learning at Rural Secondary Schools in Eastern Cape, South Africa

Abstract There is an increasing global call to adopt information and communication technologies (ICTs) in teaching and learning. ICTs have become so essential that the South African government has introduced the e-education policy. ICTs are powerful enabling tools that play a significant role in the teaching and learning process. This article reports on a study that sought to explore teachers’ perceptions of adopting ICTs in teaching and learning at some secondary schools in Eastern Cape, South Africa. The purposive sampling technique was used to identify three secondary schools and five study participants from each school. Data was collected through face-to-face interviews and focus group discussions. A thematic approach was adopted to analyse and present the collected data. The study found that the teachers had a positive attitude towards the adoption of technologies and were ready to integrate ICTs in teaching and learning but they lacked the requisite ICT skills. The article concludes that ICT is an important vehicle in education, and further recommends the training of both teachers and learners in ICT usage.
Predictive value of the serum anti-Müllerian level for spontaneous pregnancy in women after endometriosis surgery

Objective This study was performed to assess the predictive value of the anti-Müllerian hormone (AMH) serum level for spontaneous pregnancy in women after endometriosis surgery. Methods In total, 124 patients with suspected ovarian endometrioma planning to undergo laparoscopic ovarian cystectomy were divided into a high AMH group (AMH > 2 ng/mL) and low AMH group (AMH ≤ 2 ng/mL) according to their preoperative AMH levels. The postoperative AMH levels were also measured, and pregnancy outcomes were followed up. Results Twenty-one patients were excluded, and 52 pregnancies were registered in the remaining 103 patients diagnosed with endometriosis. The pregnancy rate was significantly greater in the high than low AMH group. Receiver operator characteristics analysis of preoperative AMH, postoperative AMH, and the AMH decline rate showed that preoperative AMH was associated with the greatest area under the curve. Kaplan–Meier curves showed that women in the high AMH group had a significantly higher cumulative pregnancy rate than those in the low AMH group. Conclusion The preoperative AMH level might be a useful marker to predict the occurrence of natural pregnancy and could be offered as part of the fertility strategy to women who desire pregnancy after endometriosis surgery.
Causes and Consequences of A Glutamine Induced Normoxic HIF1 Activity for the Tumor Metabolism

The transcription factor hypoxia-inducible factor 1 (HIF1) is the crucial regulator of genes that are involved in metabolism under hypoxic conditions, but information regarding the transcriptional activity of HIF1 in normoxic metabolism is limited. Different tumor cells were treated under normoxic and hypoxic conditions with various drugs that affect cellular metabolism. HIF1α was silenced by siRNA in normoxic/hypoxic tumor cells, before RNA sequencing and bioinformatics analyses were performed while using the breast cancer cell line MDA-MB-231 as a model. Differentially expressed genes were further analyzed and validated by qPCR, while the activity of the metabolites was determined by enzyme assays. Under normoxic conditions, HIF1 activity was significantly increased by (i) glutamine metabolism, which was associated with the release of ammonium, and it was decreased by (ii) acetylation via acetyl CoA synthetase (ACSS2) or ATP citrate lyase (ACLY), respectively, and (iii) the presence of L-ascorbic acid, citrate, or acetyl-CoA. Interestingly, acetylsalicylic acid, ibuprofen, L-ascorbic acid, and citrate each significantly destabilized HIF1α only under normoxia. The results from the deep sequence analyses indicated that, in HIF1-siRNA silenced MDA-MB-231 cells, 231 genes under normoxia and 1384 genes under hypoxia were transcriptionally significant deregulated in a HIF1-dependent manner. Focusing on glycolysis genes, it was confirmed that HIF1 significantly regulated six normoxic and 16 hypoxic glycolysis-associated gene transcripts. However, the results from the targeted metabolome analyses revealed that HIF1 activity affected neither the consumption of glucose nor the release of ammonium or lactate; however, it significantly inhibited the release of the amino acid alanine. This study comprehensively investigated, for the first time, how normoxic HIF1 is stabilized, and it analyzed the possible function of normoxic HIF1 in the transcriptome and metabolic processes of tumor cells in a breast cancer cell model. Furthermore, these data imply that HIF1 compensates for the metabolic outcomes of glutaminolysis and, subsequently, the Warburg effect might be a direct consequence of the altered amino acid metabolism in tumor cells.
Antioxidant properties of potato tubers (Solanum tuberosum L.) as a consequence of genetic potential and growing conditions

The concentrations of the bioactive compounds in potato tubers are determined by both genetic potential and environmental factors. The purpose of the experiment was to determine the influence of organic and integrated production on the expression of the genetic potential with respect to the antioxidant properties of potato tubers and to evaluate its stability under different environmental conditions. This phenotyping was performed on seven new breeding lines (tetraploid clones) and three modern cultivars: Jelly, Satina and Tajfun. The results indicated that production system and location significantly influenced the antioxidant capacity measured by FRAP method. Organic farming and the location Chwałowice were characterized by higher values. Furthermore, anitioxidative capacity measured by FRAP method was correlated with chlorogenic acid content (r = 0.590**) and glutathione fractions, especially with the reduced form (GSH, r = 0.692**). Multidimensional comparative analysis (MCA) proved a better development of antioxidant properties of potato tubers in the organic cultivation system when compared with the integrated. Especially favorable were growing conditions at Boguchwała (organic) and worst at Młochów (integrated). From all investigated varieties, the best antioxidant properties were found in ‘Satina’ and ‘Jelly’. Clones TG-97-403 and 13-VIII-45 developed the weakest health promoting traits.
Downregulation of LncRNA-XIST inhibited development of non-small cell lung cancer by activating miR-335/SOD2/ROS signal pathway mediated pyroptotic cell death

LncRNA-XIST participated in the regulation of Non-small cell lung cancer (NSCLC) progression, but the underlying mechanisms are still unclear. This study showed that LncRNA-XIST aberrantly overexpressed in either NSCLC tissues or cell lines comparing to their paired control groups. Knock-down of LncRNA-XIST promoted NSCLC cell apoptosis and inhibited cell proliferation, which were reversed by synergistically treating cells with pyroptosis inhibitor Necrosulfonamide (NSA). In addition, knock-down of LncRNA-XIST also promoted reactive oxygen species (ROS) production and NLRP3 inflammasome activation. In parallel, ROS scavenger N-acetyl cysteine (NAC) abrogated the effects of downregulated LncRNA-XIST on NSCLC cell pyroptosis. Furthermore, miR-335 was the downstream target of LncRNA-XIST and overexpressed LncRNA-XIST increased SOD2 expression levels by sponging miR-335. Mechanistically, miR-335 inhibitor reversed the effects of downregulated LncRNA-XIST on ROS levels and cell pyroptosis, which were abrogated by synergistically knocking down SOD2. Taken together, knock-down of LncRNA-XIST inhibited NSCLC progression by triggering miR-335/SOD2/ROS signal pathway mediated pyroptotic cell death.