Miracle-dz/UniFAR-FTUs huggingface dataset:
Physical Exertion, Fitness and Breathing

THE experiments discussed, in this pape'r were carried out during the research OD mine rescue apparatus which was instituted in 1917 by the. Scientific and Industrial Research Department.2 Their aim at' first was limited to tl;tat of determining the oxygen consumption 'of persons engaging · n differeR,t kinds of physical work,and with that object in view,a few'. · tests were made by Dr. J. S. Haldane and the writer on miners climbing i~clines in the Newbattle and Lingerwood collieries, Midlothian; these were shortly afterwards. supplemented by other tests on the same men in which. weights were lifted and certain of the common tasks of the miner were performed. During th~ early trials the men breathed ordin~ry air; but as the wearer of a, mine rescue apparatus has to breathe air ~ighly enricheQ with oxygen it was judged necessary to study ~he influence of ,_ such air on a person's capacity for physical work. It had' been a matter , of experience to the members of the Research Committee that they could perform work with greater ease and comfort while wearing a rescue , apparatus in good order, and thus obtaining air ,9ontairiing 'seventy or eighty per ce~t of oxygen,than under normal conditions. The writer, for I example, can climb a mountain faster and ·with less / fatigue when using . an efficient mine rescue apparatus than without it, notwithstanding that the apparatus weighs, in its latest form', about thirty pounds . It ,was observed that an increased o,xygen proportion in the air inha~ed was uniformly helpful_with persons of sedelJtary habits,but that when working miners were tested little or no such benefit was derived; / they were in fact generally quite indifferent as to whether they breathed air or oxygen. , A long series of experiments was then commenced in which Martin's · ergometer was principally' used as the means of measuring the rate . of exertion, and in which a quantitative.and qualitative examinatioIl was made with subj~cts of vari()usphysique . and trai.ning breathing. air, and· oxygen. ThanksJo the kindness oC the Superintendents of Pbysicaland, Bayonet Training, Scottish Cqmmand and Aldershot, several soldiers specializing in different branch of athletics were included in the tests.
Receptor Protein-tyrosine Phosphatase α Regulates Focal Adhesion Kinase Phosphorylation and ErbB2 Oncoprotein-mediated Mammary Epithelial Cell Motility*

Background: PTPα has been implicated in breast cancer, but its function remains to be defined. Results: Suppression of PTPα led to a GRB7-dependent, ErbB2-mediated increase in mammary epithelial cell migration. PTPα dephosphorylated FAK on Tyr-407. Conclusion: PTPα functions to suppress ErbB2 signaling events that lead to migration of breast cancer cells. Significance: PTPα may play positive or negative roles in signaling, depending upon context. We investigated the role of protein-tyrosine phosphatase α (PTPα) in regulating signaling by the ErbB2 oncoprotein in mammary epithelial cells. Using this model, we demonstrated that activation of ErbB2 led to the transient inactivation of PTPα, suggesting that attenuation of PTPα activity may contribute to enhanced ErbB2 signaling. Furthermore, RNAi-induced suppression of PTPα led to increased cell migration in an ErbB2-dependent manner. The ability of ErbB2 to increase cell motility in the absence of PTPα was characterized by prolonged interaction of GRB7 with ErbB2 and increased association of ErbB2 with a β1-integrin-rich complex, which depended on GRB7-SH2 domain interactions. Finally, suppression of PTPα resulted in increased phosphorylation of focal adhesion kinase on Tyr-407, which induced the recruitment of vinculin and the formation of a novel focal adhesion kinase complex in response to ErbB2 activation in mammary epithelial cells. Collectively, these results reveal a new role for PTPα in the regulation of motility of mammary epithelial cells in response to ErbB2 activation.
Distribution of vesicular glutamate transporter 2 and glutamate receptor 1 mRNA in the central nervous system of the pigeon (Columba livia)

Glutamate acts as the excitatory neurotransmitter in the central nervous system (CNS) and is mediated largely by the vesicular glutamate transporters (VGLUT1–3) and α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazole propionic acid (AMPA) types of glutamate receptors (GluR1–4) in mammals. In the present study, we determined the cDNA sequences of pigeon VGLUT2 and GluR1 and mapped the distribution of their mRNA in the pigeon CNS. The predicted amino acids of pigeon VGLUT2 and GluR1 showed a 93% identity to human VGLUT2 and GluR1 both. In situ hybridization autoradiograms showed VGLUT2 mRNA expression exclusively in the pallium of the telencephalon, and no expression in the subpallium. Within the diencephalon, VGLUT2 mRNA was more abundant in the thalamus than in the hypothalamus. Rich VGLUT2 mRNA expression was found in the optic tectum, nucleus mesencephalicus lateralis, pars dorsalis, nucleus isthmi, pars parvocellularis, isthmo‐optic nucleus, pontine nuclei, and granular layer of the cerebellum. Moderate expression was noted in the cerebellar nuclei, vestibular nuclei, cochlear nuclei, inferior olivary nucleus, and gray matter of the spinal cord. GluR1 mRNA was expressed abundantly in the pallium and subpallium of the telencephalon, but it was poor in the diencephalon, midbrain, medulla, cerebellar cortex, and gray matter of the spinal cord. These results suggest that the cDNA sequences of VGLUT2 and GluR1 in the pigeon are comparable to those of VGLUT2 and GluR1 in mammals, respectively. The distribution of pigeon GluR1 mRNA resembles that of mammals, but the distribution of VGLUT2 mRNA resembles that of both VGLUT1 and VGLUT2 in mammals. J. Comp. Neurol. 511:658–677, 2008. © 2008 Wiley‐Liss, Inc.
Does the IFRS 15 impact earnings management? Initial evidence from Italian listed companies

The purpose of the present work was to gauge the extent of the impact on earnings management derived from the adoption of International Financial Reporting Standards (IFRS) 15 as well as detecting whether the impact will be similar in different industries. To provide empirical evidence that earnings management is more frequent in some industries and less frequent in others by means of a statistical analysis, a sample of Italian listed companies in the period 2001-2017 was observed. Specifically, companies belonging to two sectors were selected: “Telecommunications” and “Utilities”. The Jones Model was applied. The statistical analysis brought to light that earnings management practices are “commonly adopted” in the “Telecommunications” industry, which is consequently highly impacted by the introduction of IFRS 15. That being said, the lesson learned from this study is that the implementation of the new principle, written to discipline the accountancy of revenues, and its consequences, must be carefully analyzed and monitored by the regulators, as well as correctly adopted by managers, as the determined revenues could have an impact on the pre-existing earning management practices. The scientific contribution of the present research also concerns the predictions on the behavior of managers that can be foreseen considering the agency theory; therefore, knowing ex-ante in which industries earnings management has a high impact, provides the option to foresee the hypothetical moves of the managers in the implementation of IFRS 15. Key words: earnings management, discretionary accruals, IFRS 15, telecommunications, utilities.
Trauma and posttraumatic stress disorder in severe mental illness.

This research assessed the lifetime prevalence of traumatic events and current posttraumatic stress disorder (PTSD) in 275 patients with severe mental illness (e.g., schizophrenia and bipolar disorder) receiving public mental health services in Concord and Manchester, New Hampshire, and Baltimore, Maryland. Lifetime exposure to traumatic events was high, with 98% of the sample reporting exposure to at least 1 traumatic event. The rate of PTSD in our sample was 43%, but only 3 of 119 patients with PTSD (2%) had this diagnosis in their charts. PTSD was predicted most strongly by the number of different types of trauma, followed by childhood sexual abuse. The findings suggest that PTSD is a common comorbid disorder in severe mental illness that is frequently overlooked in mental health settings.
Analysis of global eigenmodes in an oversized rectangular waveguide with a hard surface on one broad wall for planar slot array antenna applications

The problem of determining the eigenmodes of a rectangular waveguide with one broad hard wall formed by longitudinal corrugations with grooves filled with dielectric is considered. The dispersion equation is derived on the basis of using the asymptotic boundary conditions for corrugated surfaces. It is shown analytically that if the groove depth is equal to the value 0. 25λ/(ε−1)½ corresponding to the hard wall condition, the TE eigenmode spectrum of the waveguide comprises an infinite set of degenerated quasi-TEM modes with different transverse propagation constants and identical longitudinal propagation constants equal to the wavenumber k. Such solutions are important for understanding the local waves appearing along ridges in such waveguides, that has inspired to the invention of new so-called gap waveguides.
Performance Comparison of Binarized Neural Network with Convolutional Neural Network

Deep learning is a trending topic widely studied by researchers due to increase in the abundance of data and getting meaningful results with them. Convolutional Neural Networks (CNN) is one of the most popular architectures used in deep learning. Binarized Neural Network (BNN) is also a neural network which consists of binary weights and activations. Neural Networks has large number of parameters and overfitting is a common problem to these networks. To overcome the overfitting problem, dropout is a solution. Randomly dropping some neurons along with its connections helps to prevent co-adaptations which finally help in reducing overfitting. Many researchers have analyzed the performance of CNN and studied about the effect of dropout on CNN using datasets like MNIST and CIFAR10. The factors like Dropout rate, Dataset size, Batch Normalization layer, Filter size, and Dropout layer addition has been studied on CNN. But there is a lack of literature in the study of dropout and the various factors in Binarized Neural Network. This report will provide a brief introduction about BNN, the advantage of using dropout and the performance comparison between BNN and CNN. A detailed description of the software packages, coding environment, algorithm flow, and deep learning framework is provided. A comprehensive analysis on the performance of BNN and CNN is performed, and BNN shows near state-of-the-art results like CNN. The research demonstrates the adding of dropout layer to a BNN for MNIST and CIFAR10 datasets, and shows that it might provide improvement to the baseline BNN’s classification accuracy. Finally, the report investigates the different factors such as Dropout rate, Dataset size, Batch Normalization layer, Filter size, and Dropout layer addition on BNN.
Circulating 25-hydroxyvitamin D, VDR polymorphisms, and survival in advanced non-small-cell lung cancer.

PURPOSE We showed previously that in early-stage non-small-cell lung cancer (NSCLC), serum vitamin D levels and VDR polymorphisms were associated with survival. We hypothesized that vitamin D levels and VDR polymorphisms may also affect survival among patients with advanced NSCLC. PATIENTS AND METHODS We evaluated the relationship between circulating 25-hydroxyvitamin D levels; VDR polymorphisms, including Cdx-2 G>A (rs11568820), FokI C>T (rs10735810), and BsmI C>T (rs144410); and overall survival among patients with advanced NSCLC. Analyses of survival outcomes were performed using the log-rank test and Cox proportional hazards models, adjusting for sex, stage, and performance status. RESULTS There were 294 patients and 233 deaths, with median follow-up of 42 months. We found no difference in survival by circulating vitamin D level. The C/C genotype of the FokI polymorphism was associated with improved survival: median survival for C/C was 21.4 months, for C/T was 12.1 months, and for T/T was 15.6 months (log-rank P = .005). There were no significant effects on survival by the Cdx-2 or BsMI polymorphism. However, having increasing numbers of protective alleles was associated with improved survival (adjusted hazard ratio for two or more v zero to one protective alleles, 0.57; 95% CI, 0.41 to 0.79; P = .0008). On haplotype analysis, the G-T-C (Cdx-2-FokI-BsmI) haplotype was associated with worse survival compared with the most common haplotype of G-C-T (adjusted hazard ratio, 1.61; 95% CI, 1.21 to 2.14; P = .001). CONCLUSION There was no main effect of vitamin D level on overall survival in the advanced NSCLC population. The T allele of the VDR FokI>T polymorphism and the G-T-C (Cdx-2-FokI-BsmI) haplotype were associated with worse survival.
Pulmonary vein stenosis: initial experience with cutting balloon angioplasty

Objective: To determine the safety and effectiveness of cutting balloon angioplasty for pulmonary vein stenosis (PVS). Design and setting: Retrospective review of case notes and cardiac catheterisation data at the Royal Brompton Hospital. Main outcome measures: Diameter of pulmonary vein, tricuspid regurgitant jet velocity on echocardiogram, and percutaneous oxygen saturation before and after cutting balloon angioplasty. Results: Three patients had congenital PVS and three had PVS associated with total anomalous pulmonary venous drainage. A total of 27 PVSs were treated during 12 catheterisation procedures. Median patient age at the time of procedure was 12.5 months (range 1.5–36 months) and weight was 7.1 kg (range 2.8–11.1 kg). Minimum pulmonary vein diameter increased significantly on angiography after cutting balloon angioplasty, from mean (SD) 2.3 (0.7) mm to 4.2 (1.9) mm, mean of differences 1.9 mm (95% confidence interval (CI) 0.9 to 2.9 mm, p = 0.0013). Mean (SD) oxygen saturation rose from 79.6 (12.9)% to 83.9 (9.0)%, mean of differences 4.3% (95% CI 0.7% to 8.0%, p = 0.0238). All children’s symptoms improved subjectively. Tricuspid regurgitant jet velocity did not change significantly. The longest time interval before repeat intervention was six months. There were no acute deaths; one patient had a small pulmonary haemorrhage and developed a small aneurysm adjacent to the site of angioplasty. Conclusion: Cutting balloon angioplasty is safe in the palliation of PVS in children. It gives some acute relief but often needs to be repeated, as improvement is rarely sustained.
The Effect of Antenatal Steroids on Fetal Lung Maturation between the 34th and 36th Week of Pregnancy

Aim: To evaluate the effect of antenatal treatment with a single dose of betamethasone between the 34th and the 36th week of pregnancy on the maturation of fetal lung. Methods: To study 100 pregnant women in their 34th–36th week of pregnancy who were diagnosed as susceptible to have preterm delivery. Fifty patients did not receive betamethasone (group 1). The other 50 patients were administered 12 mg betamethasone in a single dose (group 2). Patients who delivered at least 24 h after the administration of betamethasone were included in this study. After delivery, the Apgar score and the development of respiratory distress syndrome (RDS) in the neonates were compared. Results: Group 2 babies had better Apgar scores when compared to group 1, and the difference was statistically significant. Sixteen (32%) neonates of group 1 and 7 (14%) neonates of group 2 required resuscitation, and the difference was statistically significant (p = 0.032; OR = 0.34, 95% CI 0.12–0.93). RDS was detected in 8 newborns of group 1 and 2 of group 2. The difference was statistically significant (p = 0.046; OR = 0.21, 95% CI 0.04–1.08). Conclusion: The administration of a single dose of betamethasone to pregnant women in their 34th–36th week of pregnancy who are likely to have preterm delivery reduces RDS development. There is a need for larger studies to confirm these results.
Impact of email marketing campaigns on e-commerce: a case study in the fashion industry

PURPOSE: The purpose of this study is to evaluate the impact of two type of email campaigns on e-commerce revenues, in the context of a fashion retailer. This retailer ́s e-commerce platform englobes three concepts: LA Woman, LA Kids and LA Loft. Given these circumstances, the study aims to understand under the guidance of the disposable metrics, the response from the different email campaigns to traffic driven and sales conversion on the website. DESIGN/METHODOLOGY: A case study research approach was employed with the support of data obtained from two platforms: in-house email marketing database and Google Analytics. Furthermore, some descriptive and explanatory research was conducted to address the proposed research questions. FINDINGS: The key findings display that informative email campaigns are well succeeded concerning sales conversion, while price reduction email campaigns generate a higher amount of traffic into the website. Moreover, this was reconfirmed as returning visitors to the site come mainly through informative email campaigns generated higher revenues and transactions. RESEARCH LIMITATIONS: The study presented any limitations associated with the nature of the research approach and the organisation of the data provided by the company. Future research can evaluate the results from other companies’ scope and have a more complete overview. PRATICAL IMPLICATIONS: From these results, the fashion brand used to conduct this analysis, Lanidor, can adapt its digital strategy to better address and engage their mailing list. Besides it can adapt the type of email campaigns and content to the different aims beyond their digital marketing strategy.
Business logistics models in omni-channel: a classification framework and empirical analysis

Companies are currently moving from multi-channel strategies to offer their customers an omni-channel (OC) experience. So far, OC research has been mainly tackled from a sales-based view, with numerous operational challenges to be fully investigated yet. The purpose of this paper is to investigate how companies set the logistics variables in their OC management strategy and the business logistics models currently most adopted. ,A two-step methodology was adopted. First, a systematic combining approach with scientific literature review and case studies allowed to derive a framework for classifying the key logistics variables and the related options. The framework was then used to conduct a qualitative survey targeting 92 Italian companies operating in food manufacturing, food retailing and non-food retailing. Collected data were analysed by means of cluster analysis. ,Implementing an OC management strategy requires to set 11 logistics variables belonging to four strategic areas: delivery service, distribution setting, fulfilment strategy and returns management. A broad empirical investigation showed the choices made by companies when setting the logistics variables to implement an OC management strategy. Lastly, four business logistics models, differing in terms of both business sector and OC maturity, were discussed. ,The proposed framework extends earlier studies by including additional significant logistics variables. The empirical analysis provides new insights on how to re-structure the business logistics model in OC, suggesting channel integration and the coexistence of multiple configurations as main enablers of an OC proposition.
Contribution of personal and environmental factors on positive psychological functioning in adolescents

This study examined self-esteem as mediator in the relations of personal (extraversion, neuroticism) and environmental (maternal, paternal, peer-relationships) variables with domains of positive psychological functioning (PPF) in adolescence (Satisfaction with life, Mastery, Vigor, Social Interest, Social Cheerfulness). We compared one-sided and multidimensional models using a sample of 1193 high school students (592 males and 601 females). We examined variations in adolescent PPF as a function of parenting styles via independent examination of maternal and
Aeromonas trota sp. nov., an ampicillin-susceptible species isolated from clinical specimens

Previous DNA hybridization studies established 12 Aeromonas genospecies, from which nine phenotypic species have been proposed: Aeromonas hydrophila, A. sobria, A. caviae, A. media, A. veronii, A. schubertii, A. salmonicida, A. eucrenophila, and A. jandaei. We have delineated a new Aeromonas genospecies, A. trota, on the basis of 13 strains isolated primarily from fecal specimens from southern and southeastern Asia. All strains were highly related to the proposed type strain, AH2 (ATCC 49657T): 51 to 100% (60 degrees C) and 49 to 99% (75 degrees C), with 0.2 to 2.2 divergence. AH2 was only 16 to 41% (60 degrees C) related to all other Aeromonas type strains and DNA group definition strains. The unique profile of A. trota includes negative reactions for esculin hydrolysis, arabinose fermentation, and the Voges-Proskauer test, positive reactions for cellobiose fermentation, lysine decarboxylation, and citrate utilization, and susceptibility to ampicillin, as determined by the broth microdilution MIC method and the Bauer-Kirby disk diffusion method (10 micrograms). Nine of the A. trota strains were from a single study of 165 geographically diverse aeromonads. This finding questions the efficacy of screening fecal specimens for Aeromonas spp. with ampicillin-containing media and suggests a previously unrecognized prevalence of this new species.
Analysis of Factors in Forming Fiscal Stress Index Case study: The Indonesian Government Budget

This study aims to choose a fiscal stress index that is most suitable to assess state budget condition in Indonesia. The analysis factor is used to assess several factors that can cause stress on the state budget. SPSS is used for the purposes of the analysis. There are eleven indicators of two factors that lead to fiscal stress. The assessment revealed that there is only one fiscal stress index which is suitable to assess state budget condition in Indonesia. Factors can lead to fiscal stress in Indonesia are state expenditure, debt factors, education spending, general allocation funds, profit sharing funds, special autonomy funds, health spending, debt interest payments, state obligation, and the number of population.
The Effect of Service Quality and Partnership on the Outsourcing of Information Systems Functions

Numerous corporations today are outsourcing specific information systems (IS) functions. The diversity of these outsourcing arrangements goes well beyond that associated with the more traditional facilities management. This paper examines outsourcing trends and reports the results of an empirical study on IS outsourcing. Overall IS outsourcing and its five component functions--namely, applications development, systems operations, telecommunications, end-user support, and systems planning and management--are examined for their relationships with outsourcing success. The effect of service quality of the provider and the ability of companies to build a partnership on these relationships are hypothesized and studied. Data from senior executives in 188 companies are gathered. Outsourcing success is found to be highly related to the degree of outsourcing of two functions, systems operations and telecommunications. The results indicate that transaction cost theory provides a good framework for IS outsourcing and that asset specificity of outsourcing transactions needs to be considered in any decision to outsource. Also, both service quality of the vendor and elements of partnership such as trust, cooperation, and communication are important for outsourcing success. Implications of the study for research and practice are discussed.