Miracle-dz/UniFAR-FTUs huggingface dataset:
Physico-chemical properties of Syzygium cuminii (L.) Skeels jam and comparative antioxidant study with other fruit jams

Jamun, Syzygium cuminii (L.) Skeels commonly known as Indian blackberry is a widely distributed forest tree in India and other tropical and sub-tropical regions of the world. This fruit is a rich source of natural antioxidant, vitamins and minerals having good nutraceutical and medicinal value. Physical properties of jamun fruits were studied in order to facilitate its handling and processing. This work was intended to add value to these fruits in jam production. The corresponding processed jam were compared with other commercial fruit jams in terms of proximate composition, total phenolic content, antioxidant activity and viscosity to test its overall quality parameters. According to the experimental findings, the proximate composition of jamun jam was found to be equivalent with other jams and was the richest source of total phenol with 5.58 mg GAE/g. The antioxidant activities were also highest. The percent reduction of DPPH and ABTS radicals was 47.97 and 95.02, respectively and the FRAP value was 7.36 mM ferrous sulphate equivalent/g. Pseudoplastic behavior of the processed jam was determined with the help of rheometer to check its consistency which is due to the systematic trend of pH, pectin, total soluble solids and sugar concentration at the time of processing. Viscosity of jamun jam was found to be acceptable with other commercial variety jams. Results from this work revealed essential information that could promote the commercialization of jamun jam.
A comparison of the effects of propofol and etomidate on the induction of anesthesia and on cardiopulmonary parameters in dogs.

OBJECTIVE To determine the effects of propofol or etomidate on induction quality, arterial blood pressure, blood gases, and recovery quality in normal dogs. STUDY DESIGN Randomized, blinded trial. ANIMALS Eighteen purpose-bred adult Beagles. METHODS Dogs were randomly assigned to receive propofol at 8 mg kg(-1) or etomidate at 4 mg kg(-1) intravenously (IV) administered to effect. Midazolam was administered at 0.3 mg kg(-1) IV as pre-medication at least 1 minute prior to induction. Direct arterial blood pressure, arterial blood gases, and heart rate were obtained at baseline, before induction, after induction, and for every 5 minutes afterwards until the dog began to swallow and the trachea was extubated. The dogs were allowed to breathe room air with the endotracheal tube in place. RESULTS The systolic arterial pressure (SAP) was higher in the etomidate group compared with the propofol group after induction. The SAP and mean arterial pressure (MAP) were higher in the etomidate group compared with the propofol group at 5 minutes. The recovery quality and ataxia score were worse in the etomidate group compared with the propofol group. Time from extubation to sternal recumbency and sternal recumbency to standing was longer in the etomidate group compared with the propofol group. The heart rate, PaCO(2), and HCO(3) were higher in the propofol group compared with the etomidate group after induction. The PaO(2) and SaO(2) were lower in the propofol group compared with the etomidate group after induction. The SAP and MAP were lower in the propofol group at 5 minutes compared with baseline. CONCLUSION AND CLINICAL RELEVANCE Propofol caused a decrease in SAP and MAP which was not observed with etomidate. Etomidate caused longer and poorer recoveries than propofol.
A 32.55-kHz, 472-nW, 120ppm/°C, fully on-chip, variation tolerant CMOS relaxation oscillator for a real-time clock application

This paper proposes an ultra-low power fully on-chip CMOS relaxation oscillator (ROSC) for a real-time clock application. The circuit has a distinctive feature in compensation architecture of a comparator's non-idealities caused by offset voltage and delay time. The ROSC can generate a stable and higher oscillation clock frequency without increasing power by using a low reference voltage and employing a novel compensation architecture for comparators. Measurement results in a 0.18-μm CMOS process demonstrated that the circuit can generate a stable clock frequency of 32.55 kHz. The power dissipation was 472 nW. Measured line regulation and temperature coefficient were 1.1%/V and 120ppm/°C, respectively.
Clinical and microbiological parameters in patients with self-ligating and conventional brackets during early phase of orthodontic treatment.

OBJECTIVE To determine the effect of different bracket designs (conventional brackets and self-ligating brackets) on periodontal clinical parameters and periodontal pathogens in subgingival plaque. MATERIAL AND METHODS The following inclusion criteria were used: requirement of orthodontic treatment plan starting with alignment and leveling, good general health, healthy periodontium, no antibiotic therapy in the previous 6 months before the beginning of the study, and no smoking. The study sample totaled 38 patients (13 male, 25 female; mean age, 14.6 ± 2.0 years). Patients were divided into two groups with random distribution of brackets. Recording of clinical parameters was done before the placement of the orthodontic appliance (T0) and at 6 weeks (T1), 12 weeks (T2), and 18 weeks (T3) after full bonding of orthodontic appliances. Periodontal pathogens of subgingival microflora were detected at T3 using a commercially available polymerase chain reaction test (micro-Dent test) that contains probes for Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia, and Treponema denticola. RESULTS There was a statistically significant higher prevalence of A actinomycetemcomitans in patients with conventional brackets than in patients with self-ligating brackets, but there was no statistically significant difference for other putative periodontal pathogens. The two different types of brackets did not show statistically significant differences in periodontal clinical parameters. CONCLUSION Bracket design does not seem to have a strong influence on periodontal clinical parameters and periodontal pathogens in subgingival plaque. The correlation between some periodontal pathogens and clinical periodontal parameters was weak.
Marital Satisfaction and Depression: Different Causal Relationships for Men and Women?

A sample of 150 recently married couples provided data egarding marital satisfaction and depressive symptoms Approximatey 18 months later, 116 of these couples provided complete information on marital satisfaction and depression once again The data were examined using three sets of causal models, which yielded converging results For men, causal paths emerged from depression to marital satisfaction, whereas for women causal paths were from satisfaction to depression The results are discussed in relation to the marital discord model of depression
Some Modifications of the Furlow Palatoplasty in Wide Clefts—A Preliminary Report

Objectives Authors encounter a large percentage of wide cleft palates while operating in a Third World situation. They define the terms wide clefts and unrepairable clefts in terms of measurement. They describe their technique, which they developed to deal with wide clefts. They describe some previously unreported modifications. They also report the velar lengthening obtained. Methods A total of 77 cases of primary cleft palate repaired with this technique by a single author, during the period May 2006 to February 2009, were selected for the study. These were divided into two groups on the basis of measurements. Group B consisted of all clefts deemed wide or unrepairable. Group A consisted of all other cleft palates. Difference in fistula rate was studied. Velar lengthening was measured in all patients. Observations Two fistulae occurred in Group B. The overall fistula rate for the series was 2.6%. The series consisted of 44% wide clefts, which included one case of unrepairable cleft. Lengthening in the velum ranged from 20% to 155%. Statistically significant correlations were found between narrow clefts and age group 0 to 1 year (p = .0094) and Veau Group 4 with wide clefts (p = .0194). Conclusions The Furlow technique as originally described has shortcomings. The authors describe their technique of incorporating the Furlow repair, which enables them to use it as a primary palatoplasty, in a scenario consisting of a large percentage of wide clefts in an older age group, thereby minimizing the fistula rate while increasing palatal length.
Empathy's Relationship with Adult Attachment, Self-Esteem, and Communication Self-Efficacy in Nurses

This study used descriptive correlation to examine factors affecting empathy in nurses, specifically, how empathy relates to adult attachment, self-esteem, and communication self-efficacy. Data were collected from March 16until March 27, 2015. A survey was administered to 100 nurses working in two university hospitals located in D city and K province. All data were analyzed using IBM SPSS Statistics version 20.0; general characteristics and variables were tested using descriptive statistics including frequencies and percentages. At-test and one-way ANOVA were used to test empathy according to general characteristics; Pearson’s correlation coefficient was used to test empathy’s correlation with each variable. Factors affecting empathy were analyzed using stepwise multiple regression. The results are as follows: No differences in participants’ general characteristics were found. Participants exhibiting higher attachment avoidance exhibited lower empathy; higher attachment anxiety and communication self-efficacy were correlated with higher empathy. Selfesteem was not significantly correlated with empathy. Attachment avoidance, attachment anxiety, and communication self-efficacy were found to affect empathy, with 13.1% total explanatory power. This study is significant as it identifies factors affecting empathy in nurses; this basic information may be used to structure intervention studies on empathy enhancement.
A novel sphingomyelin/cholesterol domain‐specific probe reveals the dynamics of the membrane domains during virus release and in Niemann‐Pick type C

We identified a novel, nontoxic mushroom protein that specifically binds to a complex of sphingomyelin (SM), a major sphingolipid in mammalian cells, and cholesterol (Chol). The purified protein, termed nakanori, labeled cell surface domains in an SM‐ and Chol‐dependent manner and decorated specific lipid domains that colocalized with inner leaflet small GTPase H‐Ras, but not K‐Ras. The use of nakanori as a lipid‐domain–specific probe revealed altered distribution and dynamics of SM/Chol on the cell surface of Niemann‐Pick type C fibro‐blasts, possibly explaining some of the disease phenotype. In addition, that nakanori treatment of epithelial cells after influenza virus infection potently inhibited virus release demonstrates the therapeutic value of targeting specific lipid domains for anti‐viral treatment. —Makino, A. , Abe, M. , Ishitsuka, R. , Murate, M. , Kishimoto, T. , Sakai, S. , Hullin‐Matsuda, F. , Shimada, Y. , Inaba, T. , Miyatake, H. , Tanaka, H. , Kurahashi, A. , Pack, C. ‐G. , Kasai, R. S. , Kubo, S. , Schieber, N. L. , Dohmae, N. , Tochio, N. , Hagiwara, K. , Sasaki, Y. , Aida, Y. , Fujimori, F. , Kigawa, T. , Nishibori, K. , Parton, R. G. , Kusumi, A. , Sako, Y. , Anderluh, G. , Yamashita, M. , Kobayashi, T. , Greimel, P., Kobayashi, T. A novel sphingomyelin/cholesterol domain‐specific probe reveals the dynamics of the membrane domains during virus release and in Niemann‐Pick type C. FASEB J. 31, 1301–1322 (2017) www.fasebj. org
Granger Causality Among House Price and Macroeconomic Variables in Victoria

Abstract This study analyses the dynamic causality of four macroeconomic variables on house prices. The four macroeconomic variables have interrelationships with house prices in certain lagged terms, but these relationships are not always the same as the notions put forward in prior research. The relationships are detected to be unstable in the three observation periods. The instability of these relationships would cause difficulty in predicting house prices in the market, especially for policy makers and market participants.
Association analysis of two candidate phospholipase genes that map to the chromosome 15q15.1‐15.3 region associated with reading disability

Molecular genetic studies have suggested a reading disability (RD, dyslexia) susceptibility locus on chromosome 15q. We have previously mapped this locus by association to the region surrounding D15S994. Very little is known about the neurobiological processes involved in RD, and therefore selecting positional candidate genes for analysis based upon function is difficult. Nevertheless we were able to identify two functional candidates based upon existing hypotheses. Both were phospholipase genes, phospholipase C β 2 (PLCB2) and phospholipase A2, group IVB (cytosolic; PLA2G4B). D15S944 is located within PLCB2 and is 1.6 Mb from PLA2G4B. We examined each gene for association using a mixed direct and indirect association approach, a case (n = 164)/control (n = 174) sample, and a partially overlapping sample of 178 RD parent‐proband trios from South Wales and England. Mutation analysis revealed 14 sequence variants in PLCB2 and 33 variants in PLA2G4B. All non‐synonymous SNPs were genotyped as were SNPs across each gene with maximum distance between SNPs of 6 kb. Case‐control analyses revealed modest evidence (0.01 < P < 0.05) for association between a single variant in PLCB2 and two variants in PLA2G4B. However, association was not confirmed in the family based sample. As the latter sample has previously generated replicated significant evidence for association between RD and markers/haplotypes surrounding D15S944, it should have sufficient power to detect association to variants in susceptibility gene itself. We conclude that neither gene accounts for the association signal we previously observed. As these are the only clear cut functional candidate genes in the region, identification of the putative susceptibility locus for RD on 15q will require more methodical non‐hypothesis driven positional cloning approaches. © 2004 Wiley‐Liss, Inc.
Abrupt Climate Changes: How Freshening of the Northern Atlantic Affects the Thermohaline and Wind-Driven Oceanic Circulations

Leading hypotheses for abrupt climate changes are focused on the ocean response to a freshening of surface waters in the north Atlantic. The degree to which such a freshening affects the deep, slow thermohaline, rather than the shallow, swift, wind-driven circulations of the ocean, and hence the degree to which that freshening affects climate in high rather than low latitudes, differ from model to model, depending on factors such as the treatment of diffusive processes in the oceans. Many comprehensive climate models are biased and confine the influence mainly to the thermohaline circulation and northern climates. Simulations of paleoclimates can provide valuable tests for the models, but only some of those climates provide sufficiently stringent tests to determine which models are realistic.
A versatile set of vectors for constitutive and regulated gene expression in Pichia pastoris

The budding yeast Pichia pastoris is an attractive system for exploring certain questions in cell biology, but experimental use of this organism has been limited by a lack of convenient expression vectors. Here we describe a set of compact vectors that should allow for the expression of a wide range of endogenous or foreign genes in P. pastoris. A gene of interest is inserted into a modified pUC19 polylinker; targeted integration into the genome then results in stable and uniform expression of this gene. The utility of these vectors was illustrated by expressing the bacterial β‐glucuronidase (GUS) gene. Constitutive GUS expression was obtained with the strong GAP promoter or the moderate YPT1 promoter. The regulatable AOX1 promoter yielded very strong GUS expression in methanol‐grown cells, negligible expression in glucose‐grown cells, and intermediate expression in mannitol‐grown cells. GenBank Accession Numbers are: pIB1, AF027958; pIB2, AF027959; pIB3, AF027960; pIB4, AF027961. © 1998 John Wiley & Sons, Ltd.
Over-time changes in adjustment and competence among adolescents from authoritative, authoritarian, indulgent, and neglectful families.

In a previous report, we demonstrated that adolescents' adjustment varies as a function of their parents' style (e.g., authoritative, authoritarian, indulgent, neglectful). This 1-year follow-up was conducted in order to examine whether the observed differences are maintained over time. In 1987, an ethnically and socioeconomically heterogeneous sample of approximately 2,300 14-18-year-olds provided information used to classify the adolescents' families into 1 of 4 parenting style groups. That year, and again 1 year later, the students completed a battery of standardized instruments tapping psychosocial development, school achievement, internalized distress, and behavior problems. Differences in adjustment associated with variations in parenting are either maintained or increase over time. However, whereas the benefits of authoritative parenting are largely in the maintenance of previous levels of high adjustment, the deleterious consequences of neglectful parenting continue to accumulate.
Presynaptic and postsynaptic subcellular localization of substance P receptor immunoreactivity in the neostriatum of the rat and rhesus monkey (Macaca mulatta)

The substance P receptor (SPR) gene is expressed at high levels in basal ganglia, but the paucity of information about localization of the encoded receptor protein has limited our understanding of this peptide's involvement in cellular and subcellular mechanisms in this region. Morphological evidence in the rodent striatum indicates that SPRs are expressed in postsynaptic neuronal elements, while pharmacological studies suggest the existence of presynaptic SPRs in this structure. We have examined the issue of subcellular distribution of this receptor protein in rat and primate neostriatal tissue, employing an antiserum raised against SPR.
Leadership Justice and Negative Organizational Behaviors: Mediated by Affective Commitment

According to the social identity theory, unfair treatment from superiors may arouse negative identification, which in turn leads to employees' negative behaviors in organizations. This study explored the relationships between leadership justice and two negative organizational behaviors, namely, employee silence and organizational retaliatory behavior, within Chinese context. The study was conducted through a questionnaire-based field investigation, which sampled 361 employees from 17 state-owned enterprises. The results showed that leadership justice was negatively related to employee silence and organizational retaliatory behavior, and that affective commitment partially mediated these relationships. The implications of the findings and future studies were also discussed.
Complete spontaneous regression of Merkel cell carcinoma (1986–2016): a 30 year perspective

The index case In 1986, O Rourke and Bell, in Queensland Australia, described the first case of complete spontaneous regression (CSR) of Merkel cell carcinoma (MCC). 1 At that time, the tumor was a relatively new entity, having first emerged in the medical literature in 1972 under the title ‘trabecular carcinoma of the skin’. 2 Subsequently it came to be recognized as an aggressive primary cutaneous neuroendocrine carcinoma for which wide local excision, selective lymphadenectomy and loco-regional radiotherapy now serve as the mainstay of treatment.3,4 The Australian authors’ case was of a stereotypical MCC on the cheek of a 90-year-old Australian woman of Irish ancestry. Conservative treatment by simple local excision, mandated by the patient’s advanced age and mental compromise, set the stage for events to follow. Local recurrence of the tumor and cutaneous metastases developed within a year of presentation. In the absence of therapeutic intervention, and to the great surprise of her caregivers, all of the lesions resolved spontaneously within 3 months of their appearance. The patient remained free of MCC until her death of other causes 18 months later.5 This case served as the prototype for examples of CSR of MCC to follow. In drawing parallels with other skin cancers known to regress spontaneously the authors invoked cellular immunity as the likely mechanism of regression, although their own microscopic evaluation had not disclosed evidence to support this hypothesis.
Femoroacetabular Impingement in Professional Ice Hockey Players

Background Femoroacetabular impingement of the hip joint has been identified as a major cause for hip pain in athletes. Surgical open decompression of the hip has historically been proposed as the first treatment of choice. Functional outcomes in athletes after this procedure are unknown. Purpose To describe the functional and sport-related outcome 2 years after open surgical hip decompression in a group of young professional ice hockey players suffering from cam femoroacetabular impingement. Study Design Case series; Level of evidence, 4. Methods Five young professional ice hockey players (mean age, 21.4 y at follow-up) who suffered from cam femoroacetabular impingement were treated with open surgical decompression of the hip. The operation was performed by the same surgeon, and all athletes followed the same rehabilitation guidelines. Mean follow-up time was 2.7 years. Outcome measures were recorded as time to regain symmetrical hip rotation, regain preoperative core/hip muscle strength, return to team practice, and play at competitive level. Results Hip rotation range of motion was regained by a mean 10.3 weeks. Core and hip strength values reached preoperative levels by a mean 7.8 months. Return to unrestricted team practice with the ice hockey team was achieved by a mean 6.7 months, and athletes were able to play their first competitive game after a mean 9.6 months. Three athletes were able to perform again at the highest level and in international competitions. Two athletes had to return to minor league ice hockey. Conclusion Return to high-level ice hockey after open surgical decompression of the hip was possible in this series of 5 consecutive cases.
Governance structures, ethnicity, and audit fees of Malaysian listed firms

Purpose – The purpose of this study is to examine the association between external audit fees, and board and audit committee characteristics of 736 Malaysian listed firms. It is hypothesised that good corporate governance practices reduce auditors' risk assessments, resulting in lower audit fees. Drawing on the existence of a clearly identifiable ethnic domination of board membership and ownership of Malaysian listed firms, the study also posits that Bumiputera‐controlled firms pay higher audit fees because of their weaker governance practices.Design/methodology/approach – This study employs a cross‐sectional analysis of 736 firms listed on the Bursa Malaysia for the financial year ending in 2003. Multiple regression analysis is used to estimate the relationships proposed in the hypotheses.Findings – Overall, the results of this study reveal that external audit fees are positively and significantly related to board independence, audit committee expertise, and the frequency of audit committee meetings. The.