Miracle-dz/UniFAR-FTUs huggingface dataset:
The Effect Of Restoration Type On Osseointegration of Dental Implants: A Histological Analysis In Dogs

Background and Objective: The concept of immediate occlusal loading with dental implants offers several advantages. In this research, the effect of type of restoration on Osseointegration rate of dental implants was histologically evaluated. Materials and Methods: Three months prior to implantation, the lower premolar teeth of 15 dogs were extracted. Then, 3 to 4 Maestro™ implants were placed in the healed extraction sites for each dog (n=48). Dividing the dogs into 3 groups, the implants were either loaded 48 hours later, with metallic or prefabricated acrylic crowns, or were left unloaded until the time of sacrifice. Three months after implant insertion, the animals were sacrificed and the samples were investigated to define the Osseo integration rate, lamellar and woven bone percentage and local inflammation of the regenerated bone. Results: No significant difference in the observed criteria was observed among the three groups (p>0.05); however, the unloaded group had the highest osseointegration rate and the group with metallic crown loaded had the least. The prosthesis type had no significant effect on the implant success rate (p>0.05). Lamellar and woven bone percentage of regenerated bone also did not differ in the three groups (p>0.05). One implant from each group failed in this study. Conclusion: Compared to unloaded implants, bone regeneration seems to have similar histological characteristics around immediately loaded dental implants and if properly carried out, these two kinds of restoration materials do not seem to affect the osseointegration and the bone regeneration process.
Seroprevalence of Cytomegalovirus Antibodies in Haemodialysis Patients

Results: Positivity for anti-CMV IgG was found in 254 (99.6%) of the 255 HD patients and 58 (82.9%) of the 70 controls. The difference between the 2 groups was statistically significant (P < 0.05). Positivity for anti-CMV IgM antibody was noted in 1 (0.4%) of the 255 HD patients. Conclusions: The prevalence of CMV infection among HD patients in our region was quite high. Because patients receiving HD treatment can be exposed to CMV infection, we recommend that HD patients who are susceptible to CMV infection should be identified with anti-CMV IgG and IgM specific serological tests.
Comparison between Therapeutic Efficacies of Histone Deacetylase Inhibitors and Established Drug Regimens Against Breast Cancer Cells using the Histoculture Drug Response Assay.

Purpose: Histone deacetylase inhibitors (HDACIs) induce accumulation of acetylated histones in nucleosomes, which lead to reactivate gene expression and inhibit the growth and survival of tumor cells. This study evaluated the efficacy of HDACIs in breast cancer cells in comparison with other established drug regimens. Methods: Drug responses of tumor samples from mastectomy specimens of 78 breast cancer patients were evaluated using the histoculture drug response assay (HDRA). Tumor inhibition rates (IRs) of established drug regimens such as doxorubicin, cyclophosphamide, doxorubicin with cyclophosphamide (AC), paclitaxel, docetaxel and doxorubicin with docetaxel (AT), as well as those of three HDACIs (SAHA, PXD101, and a novel compound CG-2) were evaluate. Results: The percentages of chemosensitive tumors (chemoresponsiveness) were 26.9-60.3% with established regimens and 61.5-73.1% with HDACIs when the cutoff value for inhibition rate was set at 30%. Breast cancer cells appeared to be more chemoresponsive to HDACIs than to established drug regimens. Chemoresponsiveness to AT was the highest among the established drug regimens. A combination regimen offered higher activity than did a single drug (doxorubicin vs AT; p<0.001). HER2/Neu-overexpressing breast cancers were chemosensitive to SAHA and AT (p=0.031 and 0.04, respectively). Conclusion: Our findings show that breast cancer cells were sensitive to HDACIs, with therapeutic efficacies comparable to those of established drug regimens. Specific biological markers such as HER2/Neu could be assessed for effectiveness as HDACIs chemosensitivity markers in further clinical trials.
Factors Affecting the Readiness of Medical Doctors and Patients with Chronic Conditions toward the Usage of Smartphones in the Saudi Arabian Healthcare Sector

Numerous studies have reported the rapid increase in the number of individuals who use smartphones. However, smartphones appear to be increasingly used by healthcare workers, particularly physicians and nurses. Therefore, this study aims to investigate the readiness of medical doctors and patients with chronic conditions in using and adopting smartphones for communication. This study employs the Technology Acceptance Model to examine the behavior of people in using smartphones from the perspectives of trust and rural areas. To realize our objective, we conducted a questionnaire survey that involved medical doctors and patients with chronic conditions. Our particular focus was Al Qunfudhah City in Saudi Arabia. More than 200 questionnaires were distributed to people belonging to different healthcare sectors in the rural areas of Al Qunfudhah City. Our aim was to include every possible scenario and to obtain excellent perspectives. The results that we eventually analyzed indicated that trust factor and rural areas significantly influence the readiness of people belonging to the healthcare sector toward using smartphones. The results of our study concur with the findings of other studies. Our results indicate that smartphones and other high-technology gadgets are now necessary and accepted devices in the different healthcare fields. However, further studies should explore the challenges and effects of smartphone use in the healthcare sector.
Differences in Hemoglobin and Packed Cell Volume in Blood Collected from Different Sites in Japanese Quail (Coturnix japonica)

Hemoglobin (Hb) and Packed Cell Volume (PCV) values were compared in blood collected from the following four sites of the Japanese quail: jugular, brachial, medial metatarsal veins and the heart. Ten 25-week-old hatch-mate layers of similar body weight having a hard shelled egg in the uterus were used in this study. Hb and PCV values were found to be the highest in the medial metatarsal vein followed by, in descending order, the brachial vein, the jugular vein and the heart. The heart had significantly lower values (p<0.05) compared with the jugular, brachial and medial metatarsal veins with the latter two having almost similar values. Blood samples from the jugular vein exhibited the least variability compared to other sites. The brachial vein followed by the jugular vein, were found to be suitable sites for blood sampling as well as for making injections without any significant complication. The heart puncture technique was very risky, traumatic and resulted in many side effects and should not be used, particularly in on-going experiments. Scientists should be aware of possible differences in blood constituents as a result of sampling sites. For obtaining accurate and reliable results, these points should be taken into consideration while designing an experiment or assessing comparative hematological data collected using different collection techniques.
Adeno-associated viral vector-mediated expression of NT4-ADNF-9 fusion gene protects against aminoglycoside-induced auditory hair cell loss in vitro

Abstract Conclusion: The present study suggests that adeno-associated viral vector AAV2-mediated expression of activity-dependent neurotrophic factor-9 (ADNF-9) in the cochlea could be a promising approach to protect the cochlea from aminoglycoside-induced impairment, although a further in vivo study is needed. Objectives: To construct vectors over-expressing ADNF-9 to overcome its short half-life and investigate the effect of ADNF-9 on aminoglycoside-induced hair cell impairment. Methods: We ligated ADNF-9 cDNA to the signal and leader peptides of neurotrophin 4 (NT4) and the fusion gene was named NT4-ADNF-9. NT4-ADNF-9 was subcloned into the prokaryotic expression vector pBV220 to obtain pBV220/NT4-ADNF-9. The induced recombinant ADNF-9 proteins were added into the dorsal root ganglia (DRG) cultures of embryonic day 8 chickens. In addition, we constructed the recombinant vector rAAV-NT4-ADNF-9 and transfected rat neonatal organ of Corti explants in the presence of aminoglycoside G418. Results: Our data showed that the induced expression of ADNF-9 protein could promote cultured DRG neuronal survival and neurite outgrowth. In addition, transfection of rAAV-NT4-ADNF-9 could prevent hair cell loss induced by G418 treatment in the rat organ of Corti.
Enhancing learning from lectures with epistemic primer podcasts activity - a pilot study

This study presents a pilot investigation using primer podcasts in a full-cycle epistemic activity, to prepare students for lectures in developmental psychology and support them make the most out of them. Since it is the first time podcasts are used in the course, students' appreciation of the podcasts and evaluation of their effectiveness on learning, are researched. The results show that such podcasts are experienced as motivational and beneficial for better understanding of the learning material, and that they stimulate students to engage in reflective activities. The study also demonstrates that students appreciate podcasts as part of a full-cycle epistemic activity which makes them reflect more deeply on the topics they study.
FACTORS INFLUENCING THE RESULTS OF TONSILLECTOMY AND ADENOIDECTOMY: A STUDY OF FIVE HUNDRED AND FORTY CHILDREN, CORRELATING THE PREOPERATIVE COMPLAINTS, THE AGE OF THE CHILD, THE TYPE OF TONSILS AND MICROSCOPIC STUDY OF THE TONSILS WITH THE POSTOPERATIVE RESULTS

Disappointing results following tonsillectomy and adenoidectomy are common, perhaps unnecessarily so. Diverse results in apparently similar cases are common enough to have led Dean 1 to say before a recent national meeting of otolaryngologists: "Practically, the removal of tonsils is always a gamble. " No one disagreed with him. Yet there must be differences between the children who are benefited by tonsillectomy and those who are not. A knowledge of those differences should decrease the number of disappointing results. It was with the hope of gaining an understanding of at least some of those differences that this study, in which 540 children were seen before and after their operations for a period of two years, was made. There were two objects in mind. The first object, as already intimated, was to determine, if possible, what points in the history of the case and in the appearance of the throat are significant
Similarity of vertigo attacks due to Meniere's disease and benign recurrent vertigo, both with and without migraine

Abstract Conclusion: Vertigo attacks in patients with benign recurrent vertigo (BRV) cannot be distinguished from those in patients with Meniere's disease on the basis of duration, triggers or associated symptoms (other than auditory). A subset of BRV is associated with migraine. Objective: To investigate whether clinical features of vertigo attacks can distinguish patients with BRV from those with Meniere's disease and whether subtypes of BRV can be identified. Methods: A structured interview was used to analyze features in patients with BRV, i.e. those who have normal audiograms and caloric test results even though they have had recurrent vertigo (n = 63). A group of patients with definite Meniere's disease (n = 112) served as the comparison group. Results: Compared with the Meniere's disease group, patients with BRV had a female preponderance, earlier age of onset, and increased incidence of migraine headaches (IHS criteria). With regard to the vertigo attacks, duration tended to be shorter in patients with BRV but there was a large overlap in the duration of attacks between the two groups. Triggers (stress/emotional upset, fatigue, menstrual periods) and associated symptoms (imbalance, nausea and vomiting, headache, sensitivity to light) were not significantly different in the two groups.
Identifying the affected branches of vestibular nerve in vestibular neuritis

Abstract Conclusion. The inner ear monitoring system is useful for identifying the affected branches of the vestibular nerve in cases of vestibular neuritis, providing insight about the interval for the relief of vertigo. Objective: This study conducted an inner ear monitoring system including audiometry, and caloric, ocular vestibular evoked myogenic potential (oVEMP), and cervical VEMP (cVEMP) tests in cases of vestibular neuritis for assessing the affected branches of the vestibular nerve. Methods: Twenty patients with vestibular neuritis underwent caloric, oVEMP, and cVEMP tests. Type I indicates that one of the three tests is abnormal; type II indicates that two test results are abnormal; and type III indicates that no test result is normal. Results: All patients had normal hearing, bilaterally. Nineteen (95%) of 20 patients had abnormal caloric responses, 11 patients (55%) had abnormal oVEMPs, and 5 patients (25%) had abnormal cVEMPs. Restated, of all 20 patients, 8 patients were classified as type I, 9 were type II, and 3 were type III. The mean intervals between presentation and relief of vertigo were significantly different among the three types. One year after treatment, caloric, oVEMP, and cVEMP tests returned to normal responses in three (60%) of five patients.
Relationship among uterine involution, ovarian activity, blood metabolites and subsequent reproductive performance in Egyptian buffaloes

The aim of the study to monitor post partal uterine involution, ovarian activity and biochemical parameters and it is relation to the subsequent fertility. A total sixty normal calving pluriparous buffaloes were examined between 14th and 75th day post partum (p.p.) rectaly, ultrasonically and blood sampling were collected on weekly sessions. There were differences (P 3 8 mmdiameter) in ipsilateral and contralateral ovary to the PGUH in PREG group was higher (P
A model of consumer acceptance of mobile payment

One promising area of mobile commerce (m-commerce) that is receiving growing attention globally is mobile payment (m-payment). m-payment refers to making payments using mobile devices. Understanding the determinants of consumer acceptance of m-payment will provide important theoretical contributions to the field and lead to the development of more effective m-payment devices and systems. By expanding the Technology Acceptance Model (TAM) and the Innovation Diffusion Theory (IDT), this study proposes a research model that examines the factors which determine consumer acceptance of m-payment. Significant support for the model was found in the data collected from a survey of 299 potential m-payment users. Implications for practice and suggestions for future research are provided.
Diagnosis of Partial Thickness Rotator Cuff Tears: Description of a New Diagnostic Sign and a Review of the Literature

The diagnosis of a partial thickness rotator cuff tear can be challenging. This review describes the reappearing bubble sign that can be a useful adjunct in the evaluation of a partial articular surface tear with an intratendinous extension (PAINT lesion). In addition, we review the clinical examination, radiological imaging and intra-operative techniques that may help in the detection of a partial thickness cuff tear.
Service quality and customer satisfaction measurement of mobile value-added services: a conceptual review

As the competition between mobile value-added service providers becomes very tight, each company has to be able to provide high-quality services and thus better satisfy their customers. Unfortunately, despite the increasing need for an objective measurement of service quality, there is no general agreement among service marketing scholars on how it should be conceptualised and measured. This paper presents several models of service quality measurements that can be used to assess mobile value-added service quality. This paper also discusses the measurement of customer satisfaction and how it relates to service quality.
Assessment of need for special seating and/or electronic control systems for wheelchairs among people with severe physical disabilities

The aim of this study was to establish how many people with severe physical handicap in the Cambridge Health Authority had special seating, how many still needed a seating system and to investigate the demand for electronic controls for powered wheelchairs and the overall need for something other than standard controls. A quantitative and qualitative study was conducted between September 1991 and March 1992 in health, educational, residential and domestic establishments in the Cambridge District Health Authority. A total of 215 people with no sitting or trunk balance were assessed on the Chailey seating scale where the need for special seating and/or electronic controls was assessed. Of the 215 people found who had no sitting balance, 164 sat in a wheelchair for at least half the day. Eighty three had special seating systems and 43 had special cushions or wedges. Thirteen did not have but needed special seating and 16 needed special electronic controls. The numbers who needed but did not have special seating or electronic controls for powered wheelchairs in the Cambridge HA was lower than expected. However, referral is paramount and is reliant on the knowledge and expertise of professionals working with the patients in the community. The majority of those thought to need special controls were in fact able to use adapted, standard controls rather than requiring the development of new systems.
Functional outcomes of Vibrant Soundbridge applied on the middle ear windows in comparison with conventional hearing aids

Abstract Conclusion: Vibrant Soundbridge (VSB) application to the middle ear windows yields better functional outcomes than conventional hearing aids. However, speech discrimination scores obtained with VSB and conventional hearing aids are similar. Objective: To assess audiological outcomes of round and oval window applications of VSB in comparison with conventional hearing aids. Methods: Nineteen adult patients were included in the study. The patients had mild to moderate, moderate or moderate to profound conductive or mixed hearing loss. During surgery the floating mass transducer (FMT) was placed on the round (n = 14) or oval (n = 5) window. After the surgery, audiometric evaluation and free field audiometric evaluation of both ears was carried out. Results: The hearing thresholds in the low frequencies were not significantly different between the conventional hearing aids and VSB. The functional gains obtained with oval and round window approaches were similar except for 500 Hz. The hearing thresholds in the mid and high frequencies were significantly better with VSB than the conventional hearing aids. The functional gain in the low frequencies was not significantly different between VSB and conventional hearing aids. The functional gain in the other frequencies was significantly better with VSB than conventional hearing aids.
Adoption of 3G services among Malaysian consumers: an empirical analysis

The purpose of this study is to analyse the factors influencing the usage of 3G technology in Malaysia. By extending the Technology Acceptance Model (TAM) and Diffusion of Innovation (DOI) model, this study found that perceived advantages, perceived ease of use, variety of service and social influence are able to predict the adoption of 3G among Malaysian consumers. This study allows 3G service providers to understand which factors influenced the usage of 3G in Malaysia. Other developing countries that plan to deploy 3G can also formulate business strategies using the results from this study.
High Prevalence of Mycoplasma Infections in Symptomatic (Chronic Fatigue Syndrome) Family Members of Mycoplasma-Positive Gulf War Illness Patients

AbstractImmediate family members of veterans diagnosed with Gulf War Illnesses (GWI) often complain of fatiguing illnesses, and upon analysis they report similar signs and symptoms as their veteran family members. Since a relatively common finding in Gulf War illness patients is a bacterial infection due to Mycoplasma spp. , we examined military families (149 patients: 42 veterans, 40 spouses, 32 other relatives and 35 children with at least one family complaint of illness) selected from a group of 110 veterans with Gulf War illness who tested positive (∼41%) for at least one of four Mycoplasma spp. : M. fermentans, M. hominis, M. pneumoniae or M. genitalium. Consistent with previous results, over 80% of Gulf War illness patients who were positive for blood mycoplasma infections had only one Mycoplasma spp. (Odds ratio = 9.0, 95%CL 3.3–24.3, P >.0.001), in particular M. fermentans (Odds ratio = 17.9, 95%CL 4.1–78.1, P >.0.001). In healthy control subjects the incidence of mycoplasma infection was ∼8.5% and .
Laryngeal preservation in advanced piriform sinus squamous cell carcinomas using superselective intra-arterial chemoradiation therapy with three agents

Abstract Conclusion: Superselective intra-arterial chemotherapy, which enables local control and laryngeal preservation, is a safe and useful therapy for preservation of nutrition, speech, and swallowing functions. Objective: To improve the laryngeal preservation rate in patients with hypopharyngeal piriform sinus squamous cell carcinoma by superselective intra-arterial chemotherapy. Methods: Fifty-seven patients received anterograde intra-arterial administration of docetaxel and cisplatin, and two courses of intravenous continuous infusion of 5-fluorouracil as a neoadjuvant chemotherapy over 120 h starting on day 2. Concurrent chemoradiotherapy was administered from the third course to control the primary cancer. Remaining neck lymph node metastases were treated in principle by neck dissection. Results: The 5- and 10-year survival rates were 68.5% and 58.9%, respectively. The 5-year rates by the T classification were 96.0% (10-year rate, 88.6%) in T3, 48.1% in T4a, and 16.7% in T4b. The 5- and 10-year laryngeal preservation rates were 65.2% and 62.4%, respectively. The 5-year rates by the T classification were 92.4% (10-year rate, 87.6%) in T3, 36.2% in T4a, and 16.7% in T4b. No irreversible side effects, complications, or sequelae were reported. Superselective intra-arterial chemotherapy showed superior laryngeal preservation as well as high survival rates, particularly in T3, and was considered a useful therapy.
Long-term voice results of injection with hyaluronic acid-dextranomere in unilateral vocal fold paralysis

Abstract Conclusion: Subjective and objective voice evaluation of patients injected with hyaluronic acid-dextranomere (HA-D) in the long term was not different from their preoperative values. HA-D injection does not provide an increase in the voice quality in the long term. Objective: This study was conducted to evaluate the long-term voice outcomes of injection with HA-D in patients with unilateral vocal fold paralysis (UVFP). Methods: Seventeen patients with UVFP underwent injection of HA-D. The patient group was composed of 13 women and 4 men with an age range of 34–56 years. The voice samples of patients were obtained before the injection and after the longest available follow-up. Long-term results were evaluated subjectively by the GRBAS scale and objectively by acoustic analysis. Results: The follow-up period was between 6 and 42 months. Fundamental frequency, jitter, and noise-to-harmonics ratio were decreased in the postoperative period. Shimmer was nearly the same. An increase in the S score and a decrease in R, B, and A scores were observed. Neither the GRBAS scale parameters nor the acoustic analysis results were statistically significantly different before injection and after long-term follow-up.