Miracle-dz/UniFAR-FTUs huggingface dataset:
Possible involvement of prostaglandins in psychological stress‐induced responses in rats.

1. We investigated the effect of pre‐treatment with intraperitoneal (I.P.) injection of indomethacin, an inhibitor of prostaglandin synthesis, on psychological stress‐induced responses including cardiovascular, thermoregulatory and hormonal responses in free‐moving rats. 2. Psychological stress was induced by cage‐switch stress. After the rats were placed in the novel environment, blood pressure, heart rate and body temperature significantly increased. Plasma levels of adrenocorticotrophic hormone (ACTH) and prostaglandin E2 were significantly higher 30 min after exposure to stress, in comparison to normal levels. 3. Pre‐treatment with I.P. indomethacin significantly suppressed the increases in body temperature induced by cage‐switch stress, but had no effect on increases in blood pressure and heart rate induced by this stress. Indomethacin also significantly suppressed the increases in the plasma levels of ACTH and prostaglandin E2 induced by cage‐switch stress. 4. The present results suggest that prostaglandins are involved in the development of hyperthermia and the ACTH response induced by psychological stress.
End-of-Life Care in an Australian Rehabilitation Facility for Older People: Staff Focus Groups

A qualitative study of staff experiences of end-of-life care for older people in a subacute rehabilitation facility was undertaken using three focus groups with senior multidisciplinary staff (5), junior nurses (8), and junior allied health staff (7). Content analysis revealed four major themes: being a key contact person; the quality of end–of-life care; referring to off-site service providers; and differing perspectives. These data have implications for multidisciplinary practice including staff education and capacity to change focus of care in facilities for older people dedicated to rehabilitation rather than palliation or end-of-life care.
An Optimality Proof for the PairDiff operator for Representing Relations between Words

Representing the semantic relations that exist between two given words (or entities) is an important first step in a wide-range of NLP applications such as analogical reasoning, knowledge base completion and relational information retrieval. A simple, yet surprisingly accurate method for representing a relation between two words is to compute the vector offset (\PairDiff) between the corresponding word embeddings. Despite its empirical success, it remains unclear whether \PairDiff is the best operator for obtaining a relational representation from word embeddings. In this paper, we conduct a theoretical analysis of the \PairDiff operator. In particular, we show that for word embeddings where cross-dimensional correlations are zero, \PairDiff is the only bilinear operator that can minimise the $\ell_{2}$ loss between analogous word-pairs. We experimentally show that for word embedding created using a broad range of methods, the cross-dimensional correlations in word embeddings are approximately zero, demonstrating the general applicability of our theoretical result. Moreover, we empirically verify the implications of the proven theoretical result in a series of experiments where we repeatedly discover \PairDiff as the best bilinear operator for representing semantic relations between words in several benchmark datasets.
Adaptation and Sensitivity to Postural Change in Sitting

We used 3 psychophysics methods to determine perceptible changes in seat height, seat pan angle, and backrest angle using an experimental chair. In the method of adjustment, the chosen chair settings were affected by the initial setting. For example, a high initial setting of the seat height led to a high selected setting and a low setting led to a low value. The difference between settings was referred to as not noticeable difference (NND). The method of limits was used to determine acceptable chair settings using verbal limits such as "too high" and "too low. " Using the method of constant stimuli, just noticeable differences (JNDs) were determined for chair height (1.5 cm), seat pan angle (1.2°) and backrest angle (1.7°). The corresponding values for NNDs and verbal limits were about twice as large: chair height (2.5 cm), seat pan angle (4°) and backrest angle (3°). NNDs and verbal limits are unobtrusive measures that are considered more valid than JNDs, which exaggerate the need for adjustability. The results have practical implications for the design of office chairs.
Predicting Rate of Cognitive Decline in Probable Alzheimer's Disease

Recent attempts to identify predictors of rate of decline in Alzheimer's disease (AD) have been extremely variable in choice of outcome variables, predictor variables tested, timing of assessments, and statistical approaches. In this study, a random effects regression model was applied to seek predictors of decline on the Mini-Mental State Exam in 132 patients with probable AD reassessed every 6 months for up to 7.5 years. Potential predictor variables at baseline were of three types: patients characteristics, clinical variables, and cognitive performances. The final multivariate analysis indicated that the following characteristics predicted more rapid cognitive decline: more education, history of dementia in a first degree relative, non-right handedness, better performances of Boston Naming Test, Gollin Incomplete Figures Test, and Benton Visual Retention Test-Delay, and worse performances on Responsive Naming Test, WAIS-R Block Design, and Benton Visual Retention Test-Copy.
High rate of constitutional chromosomal rearrangements in apparently sporadic ALS

Of 85 patients with ALS, the authors identified 3 patients with balanced translocations and 2 patients with pericentric inversions, all affecting distinct chromosomal loci. The high rate of constitutional aberrations (5.9%) suggests that ALS is, in part, associated with recombination-based rearrangements of genomic sequences.
Self in Art/Self As Art: Museum Selfies As Identity Work

Selfies, digital images characterized by the desire to frame the self in a picture taken to be shared with an online audience, are important reflections of the contemporary self. Much extant psychological research on selfies has taken a pathologizing view of the phenomenon, focusing on its relationship to narcissism. Our investigation seeks to contribute to a holistic, contextualized and cultural perspective. We focus on the context of museums, places where art, history, education, and culture merge into the selfie taking behaviors of patrons. First, we explore theory salient to our topic of selfie taking, finding selfies to be an important way to construct ongoing series of narratives about the self. We use concepts of identity work, dramaturgy, and impression management to understand it in this light. We relate embodiment within the museum to the selfie’s performative acts and expand upon notions that emphasize and distinguish the aesthetic elements present in many aspects of everyday life. We also question the ability of the museum selfie to destabilize. We also explore the contextual effects of mimicry and social norms. After describing our ethnographic and netnographic method, we investigate the museum selfie phenomenon. We begin with some observations on the extent of selfie-taking in contemporary culture as well as its evolution. Then, we consider selfies as a type of dynamic art form. Our analysis identifies a range of different types of museum selfies: art interactions, blending into art, mirror selfies, silly/clever selfies, contemplative selfies, and iconic selfies. Considered and studied in context, the museum selfie phenomenon reveals far more than the narcissism of the sort explored by past psychological research. The museum provides a stage for identity work that offers an opportunity for the selfie to be used not only for superficial performances but also in the pursuit of more profound self-reflection and its communication. Our ethnographic exploration of the selfie sees it as more than a quest for attention but less than a genuinely destabilizing social force. Selfie taking is complex and multidimensional, a cultural and social act, a call for connection, an act of mimicry, and part of people’s ever-incomplete identity projects.
Pidgins/Creoles and African American English

This chapter deals with the relationship between African American English (AAE) and Atlantic creoles, including U.S. English-lexifier creoles. AAE is of interest for creole studies, and language contact studies more broadly, because it displays some features of grammar and language use associated with creoles, i.e., features that are “creolisms”. It is also of interest because it has been claimed by some to have had a creole predecessor, by others merely to have been influenced by creoles and West African languages to a significantly greater extent than other American English dialects. The term “creolism” refers specifically to an AAE feature that
Generation of Verbal Stems in Derivationally Rich Language

The paper presents a procedure for generating prefixed verbs in Croatian comprising combinations of one, two or three prefixes. The result of this generation process is a pool of derivationally valid prefixed verbs, although not necessarily occuring in corpora. The statistics of occurences of generated verbs in Croatian National Corpus has been calculated. Further usage of such language resource with generated potential verbs is also suggested, namely, enrichment of Croatian Morphological Lexicon, Croatian Wordnet and CROVALLEX.
Family quality of life and psychological well-being in parents of children with autism spectrum disorders: a double ABCX model.

BACKGROUND This study examined family quality of life (FQOL) and psychological well-being from a multidimensional perspective. The proposed model was based on the double ABCX model, with severity of the disorder, behaviour problems, social support, sense of coherence (SOC) and coping strategies as components. METHOD One hundred and eighteen parents (59 mothers and 59 fathers) with a child diagnosed with autism spectrum disorders (ASD) participated in the study. Separate path analyses were performed to evaluate models of FQOL and psychological well-being for mothers and fathers. RESULTS In all models, behaviour problems had a negative indirect effect on adaptation (FQOL and psychological well-being) through SOC. For both mothers and fathers, the severity of the disorder and social support played significant roles in FQOL models. Coping strategies were related with adaptation, active avoidance coping with FQOL for fathers and positive and problem-focused coping with psychological well-being for mothers. CONCLUSIONS The results of this study highlight the value of the multidimensional approach. The specific patterns of results for mothers and fathers contribute to comprehension of the psychological adaptation of parents. Findings could be taken into account in interventions with families.
Institutional Shareholders' Investment Horizons and Corporate IT Capability: An Empirical Evaluation of the U.S. Equity Market

This PhD thesis investigates the relationship between corporate IT capability and institutional investors from two different perspectives. From the first perspective, institutional investors influence companies in their strategies and objectives. From the second, IT capability has considerable firm-internal implications that increase future prospects and firm value, which in turn attracts certain investors. The empirical results illustrate significant differences in ownership structure for firms characterized by superior IT capability. Looking deeper into this phenomenon indicates that the development of a firm’s IT capability is related to subsequent changes in the ownership structure towards more long-term oriented institutional shareholders and vice versa. This dissertation contributes to the understanding of the firm-external influences of institutional investors as well as the capital market implications of firms’ IT capability.
Space‐time clustering patterns in childhood solid tumours other than central nervous system tumours

The aetiology of most childhood solid tumours (other than central nervous system [CNS] tumours) is unclear. To investigate whether certain environmental exposures may be involved, we have analysed for space‐time clustering using population‐based data from North West England for the period 1954–98. Knox tests for space‐time interactions between cases were applied with fixed thresholds of close in space, <5 km, and close in time, <1 year apart. Addresses at birth and at diagnosis were used. Tests were repeated replacing geographical distance with distance to the Nth nearest neighbour. N was chosen such that the mean distance was 5 km. Data were also examined by a second order procedure based on K‐functions. There was significant evidence of space‐time clustering for Wilms' tumours (p = 0.03 and 0.04, using the geographical distance and nearest neighbour versions of the Knox test; and p = 0.07 and 0.03, using the geographical distance and nearest neighbour versions of the K‐function method), and soft tissue sarcomas (p = 0.01, using both the geographical distance and nearest neighbour versions of the Knox test; and p = 0.001 and 0.002, using the geographical distance and nearest neighbour versions of the K‐function method) based on time and location at birth, but not time and location at diagnosis. There was little or no evidence of space‐time clustering amongst other diagnostic groups. These are the first results to demonstrate space‐time clustering for childhood Wilms' tumours and soft tissue sarcomas. The results are consistent with environmental exposure hypotheses, relating to locations pre‐natally or peri‐natally. © 2003 Wiley‐Liss, Inc.
Induction of carbamoyl phosphate synthetase III and glutamine synthetase mRNA during confinement stress in gulf toadfish (Opsanus beta).

Gulf toadfish (Opsanus &bgr;) rapidly switch to excretion of urea as their main nitrogenous waste product under several laboratory conditions, including confinement to small volumes of water. Prior evidence suggested that the activities of two key enzymes of urea synthesis exhibited potentially different modes of upregulation during this switch, with carbamoyl phosphate synthethase III (CPSase III) activated allosterically by N-acetylglutamate, and glutamine synthetase (GSase) activated by increases in the concentration of protein. The present study was undertaken to examine additional aspects of the regulation of these enzymes. The sequence for O. beta CPSase III cDNA was obtained, and it was found to be similar to that of other piscine CPSases. The sequence also allowed us to develop riboprobes for CPSase III mRNA analysis using ribonuclease protection assays (RPAs). CPSase III mRNA was expressed in liver, muscle, kidney and intestine, in agreement with prior enzymatic measurements. Levels of CPSase III mRNA increased five- to tenfold (relative to beta-actin mRNA) in liver (but not muscle) following 48 h of confinement stress. Measured by western analysis using an antibody to chicken GSase, confined O. beta GSase protein concentrations increased eightfold over control levels, in agreement with prior and present measurements of increases in GSase activity. Furthermore, RPAs of GSase mRNA levels demonstrated an increase of fivefold during confinement.
Stress among mothers of children with intellectual disabilities in urban India: role of gender and maternal coping.

BACKGROUND The study assessed stress among mothers of young children with intellectual disabilities in urban India and examined the extent to which child functioning and maternal coping predict maternal stress. Through qualitative analyses, the study identified negative and positive dimensions of Indian mothers' caregiving experiences. MATERIALS AND METHODS Mothers completed Parenting Stress Index-Short Form, and children's teachers completed Vineland-II teacher rating form. Maternal responses to a semi-structured interview were rated to assess maternal coping and content analysed to derive qualitative themes. RESULTS Three-fourths of the sample obtained a clinically significant stress score, and maternal coping emerged as a robust predictor of stress for mothers of boys with intellectual disabilities. Qualitative analyses indicated positive and negative maternal experiences related to self, child, family and community. CONCLUSIONS The high level of stress has important clinical implications. Similarly, the significant role of maternal coping, moderating role of child gender and the multidimensional caregiving experiences have implications for future research and family interventions in India.
Untangling the Environmentalist's Paradox: Why is Human Well-Being Increasing as Ecosystem Services Degrade?

Environmentalists have argued that ecological degradation will lead to declines in the well-being of people dependent on ecosystem services. The Millennium Ecosystem Assessment paradoxically found that human well-being has increased despite large global declines in most ecosystem services. We assess four explanations of these divergent trends: (1) We have measured well-being incorrectly; (2) well-being is dependent on food services, which are increasing, and not on other services that are declining; (3) technology has decoupled well-being from nature; (4) time lags may lead to future declines in well-being. Our findings discount the first hypothesis, but elements of the remaining three appear plausible. Although ecologists have convincingly documented ecological decline, science does not adequately understand the implications of this decline for human well-being. Untangling how human well-being has increased as ecosystem conditions decline is critical to guiding future management of ecosystem services; we propose four research areas to help achieve this goal.
The Functional Role of CrkII in Actin Cytoskeleton Organization and Mitogenesis*

Crk is a member of a family of adapter proteins predominantly composed of Src homology 2 and 3 domains, whose role in signaling pathways is presently unclear. Using an in situelectroporation system which permits the introduction of glutathioneS-transferase (GST) fusion proteins into cells, we found that c-CrkII bound to p130 cas , but not to paxillin in serum-starved rat-1 fibroblasts overexpressing the human insulin receptor (HIRc cells) in vivo. 17 nm insulin stimulation dissociated the binding of c-CrkII to p130 cas , whereas 13 nm insulin-like growth factor-I, 16 nm epidermal growth factor (EGF), and 10% serum each showed little or no effect. We found that stress fiber formation is consistent with a change in the p130 cas ·c-CrkII interactions before and after growth factor stimulation. Microinjection of either GST-Crk-SH2 or -Crk-(N)SH3 domains, or anti-Crk antibody each inhibited stress fiber formation before and after insulin-like growth factor-I, EGF, and serum stimulation. Insulin stimulation by itself caused stress fiber breakdown and there was no additive effect of microinjection. Microinjection of anti-p130 cas antibody also blocked stress fiber formation in quiescent cells. Microinjection of the Crk-inhibitory reagents also inhibited DNA synthesis after insulin-like growth factor-I, EGF, and serum stimulation, but not after insulin. These data suggest that the complex containing p130 cas ·c-CrkII may play a crucial role in actin cytoskeleton organization and in anchorage-dependent DNA synthesis.
The role of corporate social responsibility in strengthening multiple stakeholder relationships: A field experiment

This research relied on a field experiment involving a real-world instance of corporate philanthropy to shed light on both the scope and limitations of the strategic returns to corporate social responsibility (CSR). In particular, the authors demonstrate that the impact of CSR in the real world is not only less pervasive than has been previously acknowledged but also more multifaceted than has been previously conceptualized. The findings indicated that contingent on CSR awareness, which was rather low, stakeholders did react positively to the focal company not only in the consumption domain but in the employment and investment domains as well. Stakeholder attributions regarding the genuineness of the company’s motives moderated these effects.
FACTORS AFFECTING THE ADOPTION OF E-PAYMENT ON TRANSPORTATION SERVICE APPLICATION USING MODIFIED UNIFIED TECHNOLOGY OF ACCEPTANCE AND USE OF TECHNOLOGY 2 MODEL 1

The increasing growth of e-commerce has encourage companies to innovate with technology, to develop a system of cashless payment in the transaction is one of the way, or commonly referred as an e-payment. However, it is known that the use of e-payment in Indonesia has not been much;it is only about 9%. Go-Jek as a popular online transportation service in Indonesia with the number of application downloads by 14 million users, has develop an e-payment system called Go-Pay. The use of Go-Pay itself is very high since it was first launched. This is a new phenomenon. Because in general the use of e-payment is still very small, but the use of Go-Pay iscontinues to increase. This study predicts the factors that affect the interests of users and the usage behavior in the using of Go-Pay as a payment transaction service of Go-Jek especially in Bandung by using the Modified Unified Theory of Acceptance And Use of Technology 2 model. The results showed that five factors in this study significantly and positively affect intention of using Go-Pay and three factors significantly and positively affect the use behavior of Go-Pay. Keywords—E-Payment, Intention, Technology Adoption, UTAUT2
Data Security Enhancement in Public Cloud Storage Using Data Obfuscation and Steganography

Data storage security is a highest concern in the cloud storage. Cloud offers huge amount of space to store their user data. This technology has proved itself as a new venture because of its ability for releasing massive computational storage with reducing cost from anywhere to any user at any time. User outsources their data to the cloud for flexible, efficient and seamless services. Once the data is sent to the cloud, the cloud service provider (CSP) alone is responsible for the data. Apart from the benefits, it has lot of security issues on the data stored in the cloud. When a user outsources the data to the cloud, there is possibility to attack the data at rest as well as data in transit. Now the concern is how to secure the data and rely on the services in cloud. In order to protect the data from unauthorized access, data should be in either encrypted format or masked format. Data security is one of the major issues which acts as an obstacle in the adoption of cloud computing. This paper proposes an elegant and novel method to enhance the security of data by associating obfuscation technique along with steganography. The proposed confidentiality technique that combines the obfuscation and steganography techniques. The main principal of obfuscation is that transforms data into new form and it must conceal the original data while the steganography hides the existence of information. The obfuscated text can be hidden in image by using Least Significant Bit(LSB) substitution method. The experimental results prove that the proposed technique has high embedding capacity and high quality stego images.