Miracle-dz/UniFAR-FTUs huggingface dataset:
Etika Bisnis Dan Profesi : Tantangan Membangun Manusia Seutuhnya

Pola hidup dan perilaku umat manusia pada era modern ini yang tidak seutuhnya memahami kodrat atau hakikat diri sebagai manusia, telah mengakibatkan nilai, norma, dan etika menjadi terabaikan, termasuk dalam dunia bisnisdan pengelolaan organisasi. Untuk itu, buku ini berusaha menjawab tantangan dan permasalahan tersebut secara sistematis mengenai hakikat keberadaan (eksistensi) manusia dan alam semesta, teori-teori etika yang berkembang, serta kaitannya dengan praktik pengelolaan bisnis yang baik (good corporate governance). Melalui contoh-contoh kasus yang dipaparkan pada akhir tiap babnya serta pembahasan contoh kode etik untuk beberapa profesi, antara lain akuntan, psikolog, advokat, dan instansi BPK-RI, pembaca akan memperoleh pemahaman seutuhnya mengenai teori dan penerapan konsep yang ada. Materi yang dibahas dalam buku ini mencakup: Bagian pertama: Fondasi Konsep dan Teori Bab 1 Manusia dan alam sekitarnya Bab 2 Filsafat, Agama, Etika, dan Hukum Bab 3 Teori-teori Etika Bagian Kedua: Lingkungan dan Etika Bisnis Bab 4 Hakikat Ekonomi dan Bisnis Bab 5 Tata Kelola Perusahaan Bab 6 Prinsip dan Kode Etik dalam Bisnis Bagian ketiga: Etika Profesi Bab 7 Kode etik akuntan Indonesia Bab 8 Kode Etik akuntan menuju era global Bab 9 Kode Etik profesi lainnya
Corticospinal tract regeneration after spinal cord injury in receptor protein tyrosine phosphatase sigma deficient mice

Receptor protein tyrosine phosphatase sigma (RPTPσ) plays a role in inhibiting axon growth during development. It has also been shown to slow axon regeneration after peripheral nerve injury and inhibit axon regeneration in the optic nerve. Here, we assessed the ability of the corticospinal tract (CST) axons to regenerate after spinal hemisection and contusion injury in RPTPσ deficient (RPTPσ−/−) mice. We show that damaged CST fibers in RPTPσ−/− mice regenerate and appear to extend for long distances after a dorsal hemisection or contusion injury of the thoracic spinal cord. In contrast, no long distance axon regeneration of CST fibers is seen after similar lesions in wild‐type mice. In vitro experiments indicate that cerebellar granule neurons from RPTPσ−/− mice have reduced sensitivity to the inhibitory effects of chondroitin sulfate proteoglycan (CSPG) substrate, but not myelin, which may contribute to the growth of CST axons across the CSPG‐rich glial scar. Our data suggest that RPTPσ may function to prevent axonal growth after injury in the adult mammalian spinal cord and could be a target for promoting long distance regeneration after spinal cord injury. © 2009 Wiley‐Liss, Inc.
Family Firms, Corporate Governance and Export

This paper tests the impact of family ownership on firms' export decisions using a rich data set of about 20,000 Italian manufacturers. The results reveal that family ownership increases the probability that firms export, although the effect weakens as ownership concentration rises. The benefit of family owners is especially pronounced when they retain control rights (ownership is aligned with control) and seek the support of external managers (ownership is partially separated from management). The role of family owners in promoting export appears to have a somewhat unsophisticated nature: family ownership promotes export particularly in industries characterized by traditional technologies and towards nearby and familiar markets. The findings support the hypothesis that families better internalize the long-run benefits of internationalization, but that their limited competencies could attenuate this benefit in export activities with a high degree of complexity.
Occupational safety and health hazards of apparel sector: perspective of Northern Province employees of Sri Lanka

Occupational Safety and Health (OSH) is an important aspect which allows an organisation to systematically manage the safety and health of the workers in a workplace. Adoption of OSH in a work environment therefore helps for the promotion and maintenance of the highest degree of physical, mental and social wellbeing in all occupations. Literature reveals that the apparel sector’s working environment is mostly associated with different kinds of workers, machinery and management teams and therefore, it should be safe and free from safety and health risks and hazards. Although there is a growing concern on OSH hazards, a lack of attention has received for researches on OSH in Sri Lankan context. Further, researches conducted on OSH in Northern in Sri Lanka are hardly found. Hence, the aim of this research is to investigate the level of exposure of employees working in apparel manufacturing organisations in Northern Province of Sri Lanka to different OSH hazards. A comprehensive literature review identified 31number of OSH hazards of apparel sector in the global and local contexts and the levels of exposure of the employees to those hazards were identified through a questionnaire survey. The data were collected from 76 number of employees working in eight different apparel manufacturing organisations in Northern Province of Sri Lanka. The collected data were analysed using RII (Relative Importance Index) method. As the study revealed, the hazards to which the apparel manufacturing employees in Northern Province of Sri Lanka are mostly exposed to are “excessive noise”, “repetitive nature of works”, “stress”, “excessive exposure to cotton dust” and “taking imbalance diet” under physical, ergonomic, psychological, chemical and biological hazard categories respectively.
In vitro effects of calcium phosphate biomaterials on fibroblastic cell behavior

The effect of synthetic granular hydroxyapatite (HAP) on cultured fibroblastic cells (L929, human bone and gingiva cells) was studied. Phagocytosis of HAP particles and resulting morphological cell changes were demonstrated by microscopic examinations. Cell counts and [3H]thymidine uptake indicated significant increases in cell proliferation and DNA synthesis. These results could account for some of the alterations of the fibroblast behavior induced by changes in intracellular levels of calcium ions released from the material.
Climate Transition Risk, Climate Sentiments, and Financial Stability in a Stock-Flow Consistent Approach

It is increasingly recognized that banks might not be pricing adequately climate risks in the value of their loans contracts. This represents a barrier to scale up the green investments needed to align the economy to sustainability and to preserve financial stability. To overcome this barrier, climate-aligned policies, such as a revision of the microprudential banking framework (for example a Green Supporting Factor (GSF )), and the introduction of stable green fiscal policies (for example a Carbon Tax (CT )), have been advocated. However, understanding the conditions under which a GSF or a CT could represent an opportunity for scaling up green investments, while preventing trade-offs on risk for financial stability, is still insufficient. We contribute to fill this knowledge gap threefold. First, we analyse the risk transmission channels from climate-aligned policies, a GSF and a CT, to the credit market and the real economy via loans contracts. Second, we assess the reinforcing feedbacks leading to cascading macro-financial shocks. Third, we consider how banks could react to the policies, i.e., their climate sentiments. In this regard, we embed for the first- time banks climate sentiments, modelled as a non-linear adaptive forecasting function into a Stock-Flow Consistent model that represents agents and sectors of the real economy and the credit market as a network of interconnected balance sheets. Our results suggest that the GSF is not sufficient to effectively scale up green investments via a change in lending conditions to green firms. In contrast, the CT could shift the bank's loans and the green/brown firms' investments towards the green sector. Nevertheless, it could imply short-term negative transition effects on GDP growth and financial stability, according to how the policy is implemented. Finally, our results show that bank's anticipation of a climate-aligned policy, through stronger climate sentiments, could smooth the risk for financial stability and foster green investments. Thus, our results contribute to understand the conditions for the onset and the mitigation of climate-related financial risks and opportunities.
Role of CX3CL1/Fractalkine in Osteoclast Differentiation and Bone Resorption1

The recruitment of osteoclast precursors toward osteoblasts and subsequent cell-cell interactions are critical for osteoclast differentiation. Chemokines are known to regulate cell migration and adhesion. CX3CL1 (also called fractalkine) is a unique membrane-bound chemokine that has dual functions for cells expressing its receptor CX3CR1: a potent chemotactic factor in its soluble form and a type of efficient cell adhesion molecule in its membrane-bound form. In this paper, we demonstrate a novel role of CX3CL1 in osteoblast-induced osteoclast differentiation. We found that osteoclast precursors selectively expressed CX3CR1, whereas CX3CL1 is expressed by osteoblasts. We confirmed that soluble CX3CL1 induced migration of bone marrow cells containing osteoclast precursors, whereas immobilized CX3CL1 mediated firm adhesion of osteoclast precursors. Furthermore, a blocking mAb against CX3CL1 efficiently inhibited osteoclast differentiation in mouse bone marrow cells cocultured with osteoblasts. Anti-CX3CL1 also significantly suppressed bone resorption in neonatal mice by reducing the number of bone-resorbing mature osteoclasts. Collectively, CX3CL1 expressed by osteoblasts plays an important role in osteoclast differentiation, possibly through its dual functions as a chemotactic factor and adhesion molecule for osteoclast precursors expressing CX3CR1. The CX3CL1-CX3CR1 axis may be a novel target for the therapeutic intervention of bone resorbing diseases such as rheumatoid arthritis, osteoporosis, and cancer bone metastasis.
Smartphone-Based Gait Recognition: From Authentication to Imitation

This work evaluates the security strength of a smartphone-based gait recognition system against zero-effort and live minimal-effort impersonation attacks under realistic scenarios. For this purpose, we developed an Android application, which uses a smartphone-based accelerometer to capture gait data continuously in the background, but only when an individual walks. Later, it analyzes the recorded gait data and establishes the identity of an individual. At first, we tested the performance of this system against zero-effort attacks by using a dataset of 35 participants. Later, live impersonation attacks were performed by five professional actors who are specialized in mimicking body movements and body language. These attackers were paired with their physiologically close victims, and they were given live audio and visual feedback about their latest impersonation attempt during the whole experiment. No false positives under impersonation attacks, indicate that mimicry does not improve chances of attackers being accepted by our gait authentication system. In 29 percent of total impersonation attempts, when attackers walked like their chosen victim, they lost regularity between their steps which makes impersonation even harder for attackers.
Toxicity of dispersed weathered crude oil to early life stages of Atlantic herring (Clupea harengus)

Reports of the chronic toxicity of dispersed crude oil to early life stages of fish perpetuate uncertainty about dispersant use. However, realistic exposures to dispersed oil in the water column are thought to be much briefer than exposures associated with chronic toxicity testing. To address this issue, the toxicity of dispersed weathered oil to early life stages of Atlantic herring (Clupea harengus) was tested for short exposure durations, ranging from 1 to 144 h. Toxicity was a function of concentration and duration of exposure, as well as of the life stage exposed. Medium South American crude oil dispersed with Corexit 9500 caused blue sac disease in embryos, but not in free‐swimming embryos. The age of embryos was negatively correlated with their sensitivity to oil; those freshly fertilized were most sensitive. Sensitivity increased after hatch, with free‐swimming embryos showing signs of narcosis. Gametes were also tested; dispersed oil dramatically impaired fertilization success. For exposures of less than 24 h, gametes and free‐swimming embryos were the most sensitive life stages. For those of more than 24 h, young embryos (<1 d old) were most sensitive. The results are presented as statistical models that could assist decisions about dispersant use in the vicinity of fish spawning habitats. Environ. Toxicol. Chem. 2010;29:1160–1167. © 2010 SETAC
The Impact of Liquidity Risk and Credit Risk on the Profitability of General Sharia Banks in Indonesia

: The purpose of this research is to analyze the influence of liquidity risk and credit risk on the profitability level of General Sharia Banks in Indonesia. Liquidity risk in this study is measured by Financing to Deposit Ratio (FDR), credit risk in is measured by Non Performing Financing (NPF) and profitability is measured by Return on Equity (ROE). The research method in this study is an explanatory research. The data were collected from the sharia banking statistics issued by the Financial Services Authority of Indonesia. We used time series data of 12 General Sharia Banks in Indonesia from the first quarter until the fourth quarter of 2014 until 2016. The data were then analyzed by using multiple linear regression analysis. The result of the study shows that the level of profitability of General Sharia Banks in Indonesia is 24% influenced by the level of liquidity risk (FDR) and credit risk (NPF). The remaining 76% is influenced by other variables not analyzed in this research. Liquidity risk (FDR) and credit risk (NPF) have a significant negative effect on the profitability level (ROE) of General Sharia Banks in Indonesia.
Perceptions of distance students on the efficacy of Online Public Access Catalogue as an information retrieval tool at the University of Zambia

The survey aims to investigate distance students’ perceptions of the efficacy of the online catalogue as a tool for information retrieval at the University of Zambia. A survey research design has been adopted in the study. Convenient sampling method was used to select 160 distance students. A structured questionnaire was developed and distributed to undergraduate distance students. The Statistical Package for Social Sciences (SPSS) software was used to analyse quantitative data into frequencies and percentages. The study established majority of distance students rarely used the online public access catalogue in exploiting the resources in the university library. Instead they employed shelf-to-shelf browsing in information searching and retrieval skills. Lack of proper orientation and user education were identified as major factors militating against their maximum utilization and exploitation of the resources in the university library. The findings of the study will inform stakeholders on how best to turn around the negative trends of OPAC.
Physiological Effects of Transcendental Meditation

Oxygen consumption, heart rate, skin resistance, and electroenceph-alograph measurements were recorded before, during, and after subjects practiced a technique called transcendental meditation. There were significant changes between the control period and the meditation period in all measurements. During meditation, oxygen consumption and heart rate decreased, skin resistance increased, and the electroencephalogram showed specific changes in certain frequencies. These results seem to distinguish the state produced by transcendental meditation from commonly encountered states of consciousness and suggest that it may have practical applications.
Assessing current company reports according to the IIRC integrated reporting framework

Purpose This paper aims to investigate the adherence level of current company reports to the International Integrated Reporting Council (IIRC) integrated reporting framework through analysis of whether and to what extent those reports include the content elements of this framework. This study also aims to examine the impact of corporate sustainability characteristics on the adherence level of current company reports to the integrated reporting framework. Design/methodology/approach The sample for this research comprises the non-financial companies which were listed on Borsa Istanbul, the Turkish stock exchange, as of 31 December 2015. The authors constructed a disclosure index based on the content elements of the IIRC reporting framework. They then measured the integrated reporting disclosure score (IRS) of each company through a manual content analysis of its annual reports and stand-alone sustainability reports. To test the hypotheses, the authors performed a number of statistical analyses. Findings The authors determined that current company reports mainly present generic risks rather than company-specific; provide positive information while dismissing negative information; present financial and non-financial initiatives separately; lack a strategic focus; and include backward-looking information rather than forward-looking information. Consistent with the predictions, the authors found that the IRS is significantly and positively associated with sustainability reporting, Global Reporting Initiative (GRI) adoption, sustainability index listing and the presence of a sustainability committee. Originality/value This study contributes to the literature by enhancing the understanding of integrated reporting practices through the application of a checklist based upon the IIRC integrated reporting framework. Further, this study contributes to the literature by evaluating the impact of corporate sustainability characteristics on IRS.
Proteasome inhibitor therapy in multiple myeloma

Multiple myeloma remains incurable despite available therapies, and novel therapies that target both tumor cell and bone marrow microenvironment are urgently needed. Preclinical in vitro and in vivo studies show remarkable anti–multiple myeloma activity of the proteasome inhibitor bortezomib/PS-341 even in multiple myeloma cells refractory to multiple prior therapies, including dexamethasone, melphalan, and thalidomide. Based on these findings, the U.S. Food and Drug Administration recently approved the first proteasome inhibitor bortezomib (Velcade), formerly known as PS-341, for the treatment of relapsed/refractory multiple myeloma. Bortezomib therapy has set an outstanding example of translational research in the field of oncology. Genomics and proteomic studies further provide rationale for combining bortezomib with conventional and novel agents to inhibit multiple myeloma growth, overcome drug resistance, reduce attendant toxicity, and improve patient outcome in multiple myeloma.
A Novel Variant, NDM-5, of the New Delhi Metallo-β-Lactamase in a Multidrug-Resistant Escherichia coli ST648 Isolate Recovered from a Patient in the United Kingdom

ABSTRACT A new variant of the New Delhi metallo-enzyme (NDM) carbapenemase was identified in a multidrug-resistant Escherichia coli ST648 isolate recovered from the perineum and throat of a patient in the United Kingdom with a recent history of hospitalization in India. NDM-5 differed from existing enzymes due to substitutions at positions 88 (Val→Leu) and 154 (Met→Leu) and reduced the susceptibility of E. coli TOP10 transformants to expanded-spectrum cephalosporins and carbapenems when expressed under its native promoter.
TOWARDS REGIONAL SUSTAINABLE DEVELOPMENT VIA GOVERNMENT FINANCIAL TRANSPARENCY: EVIDENCE FROM INDONESIA

We examine factors that influence financial transparency in local government website in Indonesia which is motivated by the low level of financial transparency displayed in the local government’s official website. The purpose of this research is to obtain empirical evidence on the effect of entity characteristics represented by the size of local government & taxes per capita, political factors represented by political power & e-government, and environmental factors represented by internet visibility & income per capita, on financial transparency displayed in local government website. By using three dimensions of financial transparency constructed from the combination of NGO Transparency International and government regulation, we try to assess financial transparency displayed in local government website more comprehensinvely. The observation was conducted at the end of August 2017 until September 2017. Logistic regression analysis was applied to evaluate the model. Using 411 samples from 514 Indonesia local governments in 2015, our data show that the level of financial transparency in local government website is still very low. Furthermore, the findings show that size of the local government, internet visibility, and e-government are positively associated with local government’s financial transparency, but other variables including taxes per capita, political power, and income per capita have no effect on financial transparency.
Gene Expression and Receptor Binding of Insulin‐Like Growth Factor‐II in Pig Choroid Plexus Epithelial Cells

Abstract: To elucidate the function of insulin‐like growth factor‐II (IGF‐II) in the choroid plexus, the gene expression and receptor binding of IGF‐II were studied in isolated epithelial cells from the porcine choroid plexus. The choroid plexus expressed multiple IGF‐II transcripts of 1.2, 1.6, 2.4, and 4.4 kb, at levels higher than those found in porcine liver and kidney. These data suggest that IGF‐II is synthesized by the choroid plexus. Choroid plexus epithelial cells contained high levels of IGF‐I receptors on the cell surface whereas very low levels of receptor binding were found for 125I‐IGF‐II and I25l‐insulin. Solubilization of epithelial cells showed that a large proportion of the IGF‐I receptors were present in the detergent‐insoluble fraction whereas IGF‐II receptors and insulin receptors were concentrated in the detergent‐soluble fraction. These results suggest that IGF‐I receptors are located in clathrin‐coated pits of the plasma membrane whereas IGF‐II receptors and insulin receptors are present in endosomal vesicles. The tyrosine kinase activity of the IGF‐I receptor β‐subunit was stimulated by IGF‐I, IGF‐II, and insulin, in order of potency, suggesting that these peptides exert a regulatory function in the chdroid plexus epithelium. In conclusion, we propose that the IGF‐I receptor tyrosine kinase on the surface of the epithelial cells in the pig choroid plexus mediates effects of IGF‐I and IGF‐II, whereas IGF‐II receptors are down‐regulated due to the synthesis and secretion of IGF‐II in these cells.