Miracle-dz/UniFAR-FTUs huggingface dataset:
Knowledge sharing and social technology acceptance model: promoting local events and festivals through facebook

Este estudio examina la pagina de Facebook "eventos" como un medio para la promocion de eventos especiales para los consumidores. Propone un Modelo de Aceptacion de Tecnologia Social, una extension del Modelo de Aceptacion de Tecnologia, para examinar la influencia de la confianza, la fuerza de las relaciones (factores de intercambio de conocimientos), y el disfrute percibido en la formacion de las actitudes de los consumidores hacia Facebook y las intenciones de los consumidores a asistir a un evento. Un total de datos 155 se recogieron a traves de una encuesta realizada en el de un organizador de eventos especiales Facebook "pagina. " Los resultados sugieren que los usuarios de la "confianza, fuerza de las relaciones, y el disfrute percibido afectan significativamente los usuarios 'aceptacion de Facebook y de su intencion de asistir a un evento. El impacto teorico del estudio actual de intercambio de conocimientos puede ser de gran valor para entender el comportamiento de uso de Facebook. Por otra parte, mediante la integracion de los conceptos de confianza y la fuerza de las relaciones, apoyo empirico muestra que los medios sociales proporciona marketing de eventos un medio para beneficiarse de los vinculos fuertes y debiles de las redes sociales individuales.
Advances in the Hemodialysis Management of Phenobarbital Overdose

&NA; When a comatose man requiring ventilatory support for acute ingestion of phenobarbital was admitted to the University of Utah Hospital, he was managed by a multispecialty team, which included a nephrologist and a clinical pharmacologist. Since the patient could not be moved to the dialysis unit, a mobile dialysis machine was used. A negative‐pressure adapter was used in conjunction with a batch‐type dialysis machine to create a single‐pressure dialysate delivery system. Blood was delivered to the dialyzer and returned to the patient through bilateral femoral catheters that had been placed percutaneously. Pharmacokinetic studies were performed and compared to the disappearance of phenobarbital by conservative measures alone after the patient had awakened and dialysis was discontinued.
Combined tamoxifen and luteinizing hormone-releasing hormone (LHRH) agonist versus LHRH agonist alone in premenopausal advanced breast cancer: a meta-analysis of four randomized trials.

PURPOSE The logic behind the application of luteinizing hormone-releasing hormone (LHRH) agonists in combination with tamoxifen in premenopausal women is that LHRH agonists on the one hand suppress the tamoxifen-induced stimulation of the pituitary-ovarian function and, on the other hand, seem as effective as surgical castration. This meta-analysis combines all randomized evidence to compare the combined treatment with LHRH agonist alone with respect to overall survival, progression-free survival, and objective response in premenopausal women with advanced breast cancer. PATIENTS AND METHODS Four clinical trials randomizing a total of 506 premenopausal women with advanced breast cancer to LHRH agonist alone or to the combined treatment of LHRH agonist plus tamoxifen were identified. Meta-analytic techniques were used to analyze individual patient data from these trials. RESULTS With a median follow-up of 6.8 years, there was a significant survival benefit (stratified log-rank test, P = .02; hazards ratio [HR] = 0.78) and progression-free survival benefit (stratified log-rank test, P = .0003; HR = 0.70) in favor of the combined treatment. The overall response rate was significantly higher on combined endocrine treatment (stratified Mantel Haenszel test, P = .03; odds ratio = 0.67). CONCLUSION The combination of LHRH agonist plus tamoxifen is superior to LHRH agonist alone in premenopausal women with advanced breast cancer. Therefore, if a premenopausal woman with advanced breast cancer is thought to be suitable for endocrine treatment, it is proposed that the combination of a LHRH agonist plus tamoxifen be considered as the new standard treatment.
Narratives of Success and Failure in Systems Development

This paper explores a narrative perspective on ‘success’ and ‘failure’ in computer systems development. Organizational narratives can be seen as sense-making devices and as having a purposive aspect in the ways in which they evolve and change and influence behaviour. Narratives like success and failure in particular can be seen as persuasive rhetorics used in legitimizing particular courses of action. The narrative approach challenges more accepted notions, particularly rationalist views that see computer success/failure as outcomes brought about by simple causation. It also reveals the limitations of process models of IT success/failure, though these stress a more complex form of decision making around IT. In the paper, these issues are explored in contrasting projects in financial services firms. In two case studies, computer success and failure emerge not as discrete conditions, but as interacting themes employed by organizational members in response to the circumstances they confront. The corporate capacity to build success out of failure, and to distance the new from the old, discriminated between successful and unsuccessful projects.
Protein biomarker identification in the CSF of patients with CNS lymphoma.

PURPOSE Elucidation of the CSF proteome may yield insights into the pathogenesis of CNS disease. We tested the hypothesis that individual CSF proteins distinguish CNS lymphoma from benign focal brain lesions. METHODS We used a liquid chromatography/mass spectrometry-based method to differentially quantify and identify several hundred CSF proteins in CNS lymphoma and control patients. We used enzyme-linked immunosorbent assay (ELISA) to confirm one of these markers in an additional validation set of 101 cases. RESULTS Approximately 80 CSF proteins were identified and found to be present at significantly different concentrations, both higher and lower, in training and test studies, which were highly concordant. To further validate these observations, we defined in detail the expression of one of these candidate biomarkers, antithrombin III (ATIII). ATIII RNA transcripts were identified within CNS lymphomas, and ATIII protein was localized selectively to tumor neovasculature. Determination of ATIII concentration by ELISA was significantly more accurate (> 75% sensitivity; > 98% specificity) than cytology in the identification of cancer. Measurement of CSF ATIII levels was found to potentially enhance the ability to diagnose and predict outcome. CONCLUSION Our findings demonstrate for the first time that proteomic analysis of CSF yields individual biomarkers with greater sensitivity in the identification of cancer than does CSF cytology. We propose that the discovery of CSF protein biomarkers will facilitate early and noninvasive diagnosis in patients with lesions not amenable to brain biopsy, as well as provide improved surrogates of prognosis and treatment response in CNS lymphoma and brain metastasis.
Estimating the Potential Economic Value of Seasonal Forecasts in West Africa: A Long-Term Ex-Ante Assessment in Senegal

Abstract Recent improvements in the capability of statistical or dynamic models to predict climate fluctuations several months in advance may be an opportunity to improve the management of climatic risk in rain-fed agriculture. The aim of this paper is to evaluate the potential benefits that seasonal climate predictions can bring to farmers in West Africa. The authors have developed an archetypal bioeconomic model of a smallholder farm in Nioro du Rip, a semiarid region of Senegal. The model is used to simulate the decisions of farmers who have access to a priori information on the quality of the next rainy season. First, the potential economic benefits of a perfect rainfall prediction scheme are evaluated, showing how these benefits are affected by forecast accuracy. Then, the potential benefits of several widely used rainfall prediction schemes are evaluated: one group of schemes based on the statistical relationship between rainfall and sea surface temperatures, and one group based on the predictions o.
Informal Kinship Care of Orphans in Rural China

This study examines kinship care of orphans throughout China. It finds that in addition to children becoming orphaned if both parents die, some children are treated as orphans when their father dies and rural traditional kinship care obligations restrict the viability of widowed mothers continuing to care for their child. When mothers are forced for socioeconomic reasons to leave the paternal extended family, children effectively become orphans, dependent on ageing grandparents. Girls and disabled children are most at risk. Implementing financial and other support to orphans, widowed mothers and kinship carers could improve the sustainability of these family relationships.
Tweets and Trades: The Information Content of Stock Microblogs

Microblogging forums (e.g., Twitter) have become a vibrant online platform for exchanging stockâ€ related information. Using methods from computational linguistics, we analyse roughly 250,000 stockâ€ related messages (soâ€ called tweets) on a daily basis. We find an association between tweet sentiment and stock returns, message volume and trading volume, as well as disagreement and volatility. In contrast to previous related research, we also analyse the mechanism leading to an efficient aggregation of information in microblogging forums. Our results demonstrate that users providing above average investment advice are retweeted (i.e., quoted) more often and have more followers, which amplifies their share of voice.
Impact of Journalism Educators on Media Performance and Journalism Practice in Taiwan

﻿This study examines the role of journalism educators in Taiwan in shaping their students’ views of the profession, and the extent to which the ethics and values taught at university are practiced in the newsroom. Interviews were conducted with educators and journalism graduates from National Chengchi University, a public institution recognized as setting the standard for journalism education in the country, and Nanhua University, a private institution. The study indicates that an individual educator’s attitudes and opinions on concepts such as public service, news value, and news ethics have an impact on the views of students, although business and political pressures, as well as Taiwan’s highly competitive media market, may compromise journalistic values and ethics.
A Family with Craniofrontonasal Syndrome and a Mutation (p.G151S) in the EFNB1 Gene: Expanding the Phenotype

Craniofrontonasal syndrome (CFNS) is a rare genetic entity with X-linked dominant inheritance. CFNS is due to mutations in the Ephrin-B1 (EFNB1) gene. It is characterized by brachycephaly, frontonasal dysplasia, palate/lip defects, dental malocclusion, short neck, split nails, syndactyly, toe and finger defects, and minor skeletal defects. Intelligence is usually unaffected. CFNS exhibits unexpected manifestations between males and females as the latter are more affected. Cellular or metabolic interference due to X inactivation explains the more severe phenotype in heterozygous females. One family with several members affected with CFNS and 100 healthy controls were examined. DNA from leukocytes was isolated to analyze the EFNB1 gene. We did molecular modeling to assess the impact of the mutation on the EFNB1-encoded protein. DNA sequencing analysis of the EFNB1 gene of the affected members showed the heterozygous missense mutation c.451G>A in the EFNB1 gene (GRcH38, chrX: 68,839,708; GERP score in hg38 of 9.961). This transition mutation resulted in the substitution of Gly at position 151 by Ser. Analysis of the healthy members of the family and 100 unrelated controls showed a normal sequence of the EFNB1 gene. Phenotypes of the patients in this family differ from the classical CFNS due to the decreased size of sulci and fissures, subarachnoid space and ventricles, and the absence of a cleft lip/palate.
Towards the Development of Affective Facial Expression Recognition for Human-Robot Interaction

Affective facial expression is a key feature of non-verbal behavior and is considered as a symptom of an internal emotional state. Emotion recognition plays an important role in social communication: human-human and also for human-robot interaction. This work aims at the development of a framework able to recognise human emotions through facial expression for human-robot interaction. Simple features based on facial landmarks distances and angles are extracted to feed a dynamic probabilistic classification framework. The public online dataset Karolinska Directed Emotional Faces (KDEF) [12] is used to learn seven different emotions (e.g. angry, fearful, disgusted, happy, sad, surprised, and neutral) performed by seventy subjects. Offline and on-the-fly tests were carried out: leave-one-out cross validation tests using the dataset and on-the-fly tests during human-robot interactions. Preliminary results show that the proposed framework can correctly recognise human facial expressions with potential to be used in human-robot interaction scenarios.
Accounting for the water impacts of ethanol production

Biofuels account for 1–2% of global transportation fuel and their share is projected to continue rising, with potentially serious consequences for water resources. However, current literature does not present sufficient spatial resolution to characterize this localized effect. We used a coupled agro-climatic and life cycle assessment model to estimate the water resource impacts of bioenergy expansion scenarios at a county-level resolution. The study focused on the case of California, with its range of agroecological conditions, water scarcity, and aggressive alternative fuel incentive policies. Life cycle water consumption for ethanol production in California is up to 1000 times that of gasoline due to a cultivation phase that consumes over 99% of life cycle water use for agricultural biofuels. This consumption varies by up to 60% among different feedstocks and by over 350% across regions in California. Rigorous policy analysis requires spatially resolved modeling of water resource impacts and careful consideration of the various metrics that might act to constrain technology and policy options.
Do Firms Manage Fair Value Estimates? An Examination of SFAS 142 Goodwill Impairments

I find that goodwill write-offs under Statement of Financial Accounting Standards No. 142 (SFAS 142) are associated with future expected cash flows as mandated by the standard. However, there are indications that goodwill write-offs lag behind the economic impairment of goodwill. Additional analysis reveals that the association between goodwill write-offs and future cash flows is insignificant for firms with contemporaneous restructuring. I hypothesize that this finding is due to agency-based motives. Finally, I examine a sample of non-impairment firms in which there are indications that goodwill is impaired. I fail to find convincing evidence that these firms are opportunistically avoiding impairments. Copyright (c) 2009 The Author Journal compilation (c) 2009 Blackwell Publishing Ltd.
Board Seat Accumulation by Executives: A Shareholder's Perspective

While reformers have argued that multiple directorships for executives can destroy value, we investigate firms with executives that accept an outside directorship and find negative announcement returns only when the executive's firm has greater agency problems. When fewer agency concerns exist, additional directorships relate to increased firm value. Announcement returns are also higher when executives accept an outside directorship in a financial, high-growth, or related-industry firm. Our results suggest that outside directorships for executives can enhance firm value, which has important implications for firms employing executives nominated for outside boards and for policy recommendations restricting the number of directorships. Copyright 2005 by The American Finance Association.
Muscarinic regulation of pacemaker frequency in murine gastric interstitial cells of Cajal

Peristaltic contractions in the stomach are regulated by the spread of electrical slow waves from the corpus to the pylorus. Gastric slow waves are generated and propagated by the interstitial cells of Cajal (ICC). All regions distal to the dominant pacemaker area in the corpus are capable of generating slow waves, but orderly gastric peristalsis depends upon a frequency gradient in which the corpus pacemaker frequency exceeds the antral frequency. Cholinergic, muscarinic stimulation enhances pacemaker frequency. We investigated this phenomenon using intact murine gastric muscles and cultured ICC. Acetylcholine (ACh) increased the frequency of slow waves in antrum and corpus muscles. The increase was significantly greater in the antrum. ACh and carbachol (CCh) increased the pacemaker currents in cultured ICC. At high doses of CCh, transient pacemaker currents fused into sustained inward currents that persisted for the duration of stimulation. The effects of CCh were blocked by low doses of the M3 receptor antagonist 1‐dimethyl‐4‐diphenylacetoxypiperidinium. Frequency enhancement by CCh was not affected by forskolin, but the phospholipase C inhibitor U‐73122 inhibited both the increase in frequency and the development of tonic inward currents. 2‐Aminoethyldiphenyl borate also blocked the chronotropic responses to CCh. Inhibitors of protein kinase C did not block responses to CCh. These studies show that mice are an excellent model for studying mechanisms that regulate gastric slow‐wave frequency. CCh, apparently via production of inositol 1,4,5‐trisphosphate, accelerates the frequency of pacemaker activity. High concentrations of CCh may block the entrainment of pacemaker currents, resulting in a tonic inward current.
A study of 60 patients with percutaneous trigger finger releases: clinical and ultrasonographic findings

We present the clinical results and ultrasonographic findings of 61 trigger digits treated with percutaneous A1 pulley release. An endoscopic carpal tunnel knife was used for the release in the outpatient department. The mean follow-up period was 3.5 months. A total of 55 digits (90%) had complete relief of their triggering postoperatively. Six digits (10%) had Grade 2 triggering clinically in the early postoperative period.The complications included six cases of insufficient release (10%), scar sensitivity in one patient, short-term hypoaesthesia in three digits (5%), and flexor tendon laceration noted on postoperative ultrasonography in eight digits (13%). No neurovascular damage was noted on the postoperative ultrasonography. Ultrasonograpy provides information about tendon laceration and changes in thickness of the pulleys and confirm A1 pulley release after surgery, but it does not alter clinical decision-making. We believe that pre- and postoperative ultrasonograpy does not need to be included as a routine examination.
IN SEARCH FOR THE UNIQUE: CAN FIRM-SPECIFIC ADVANTAGES BE EVALUATED?

Strategy, whatever its different definitions, entails an attempt by a firm to achieve and sustain competitive advantage against other firms. Competitive advantage can be achieved if the firm is able to be different. Success is based on using a unique strategy. Success is defined as the ability to gain abnormal profits, not simply to stay alive in a competitive industry. the ability to protect the uniqueness against imitators ensures continued success. Strategy theory research is diverse, and can be divided into distinct schools of thought. Certain researchers describe the process of strategy formation. Others are prescriptive, concerned with analytical tools for strategy formulation. Among strategy content researchers, much recent research concentrates on industry analysis techniques. Since strategy is defined as the ability to gain an advantage, a cross‐sectional study of industry conditions can show the constraints on such a strategy, but is far less useful in defining how to achieve and sustain a competitive advantage. A critical aspect in understanding competitive advantage is that of the identification of firm‐specific advantages, particularly in an outlying rather than the average ‘representative’firm. the process by which managers of such firms gain insights on strategic vision often affects the results. This article calls for understanding the unique or ‐ as a minimum ‐learning to recognize uniqueness (e.g. as someone running a venture fund reviewing proposals for investment). It is concerned with how a strategy can be evaluated ex ante by outsiders to predict its probability of success. The strategy research field is not mature enough to settle on only some conceptual boxes. the article also calls for several accepted modes of investigation, including history and political behaviour, to understand better the process by which firms attempt to achieve unique advantages and the evolution of resource deployment.
Birth outcome in incarcerated, high-risk pregnant women.

OBJECTIVE To compare birth outcomes in incarcerated women with a recent history of drug use to those of nonincarcerated women in a methadone maintenance program. STUDY DESIGN We retrospectively analyzed pregnancy outcome in 149 women who delivered at full term between 1993 and 1996. Thirty-one patients incarcerated during pregnancy (group 1) were compared with 47 patients enrolled in our methadone maintenance program (group 2) and with a control group of 71 randomly chosen patients (group 3). Drug use, age, parity, number of visits, infant birth weight, low birth weight and Apgar scores were compared. RESULTS The methadone maintenance group had significantly fewer clinic visits. All the patients in groups 1 and 2 were cigarette smokers, whereas 12.5% of the control group smoked. Over 78% of incarcerated women admitted using drugs immediately prior to imprisonment as compared to 4.11% in group 3 and 100% in group 2 (P < .001). The three groups differed significantly with respect to infant birth weight (P < .001). CONCLUSION Cessation of drug use followed by adoption of a health-promoting lifestyle and adequate prenatal care of incarcerated women leads to an improvement in birth outcome. Furthermore, provision of prenatal care on site is a suitable alternative for the care of incarcerated pregnant women and eliminates the need to bring patients in chains to outside clinics.
An empirical study on the integrative pre-implementation model of technology acceptance in a mandatory environment

ABSTRACT Technology acceptance has been studied extensively within the IS discipline. Few, if any, have studied end users’ acceptance of newly implemented technologies within organisational contexts before end users start using the technology. Thus, by integrating variables from multiple relevant literature, this research attempts to answer this research question: will the introduction of a richer model for technology acceptance in a mandatory adoption environment, specifically in the pre-implementation phase, allow us to capture and account for the complexities of organisational technology implementations? The research model was tested in an organisational setting where a new content management system was being implemented. A total of 148 employees participated in this survey and partial least squares method was used to analyse the data to test the model. Implementation climate, valence, attitude, and perceived ease of use positively influence goal commitment to technology acceptance in a mandatory environment, and the model has displayed relatively large explanatory and predictive power. Theoretical and practical implications are discussed in the paper.