Miracle-dz/UniFAR-FTUs huggingface dataset:
Assessing the correlation between labour income risk and household portfolio investment in risky assets: evidence from Italian longitudinal data

The aim of the present paper is to assess the correlation between labour income volatility and household investment in risky assets, using a representative sample of Italian households (SHIW, Bank of Italy). The paper firstly analyses the covariance structure of earnings in Italy, at a household and at an individual level. The evidence found is used to construct a measure for labour income risk. The variable so created is then introduced as a regressor in a reduced form estimation modelling the determinants of household portfolio allocation in risky assets. The regression analyses shows that labour income volatility is negatively correlated with household investment in risky assets. This finding is consistent with theoretical predictions, and is robust to different specifications and different econometric techniques. The regression results also show that disentangling labour income risk for household heads (“husband and wife”) does not add explicative power to the model, whilst a joint measure of labour income risk is negatively correlated with the choice of investing in risky assets. When incomes of household heads are positively correlated, and labour income risk is consequently perceived as overall higher, household portfolio allocation is switched towards safer investment decisions.
1 3 F eb 2 01 4 Einstein ’ s cosmological considerations

The objective of this paper is not simply to present an histor ical overview of Einstein’s cosmological considerations, but to discuss the central ro le they played in shaping the paradigm of relativistic cosmology. This, we’ll show, was a result of both his actions and, perhaps more importantly, his inactions. Accordingly, discussion won’ t simply be restricted to Einstein’s considerations, as we’ll analyse relevant contributions t o the relativistic expansion paradigm during the approximately twenty years following Slipher’s fir t redshift measurements in 1912. Our aim is to shed some light on why we think some of the things w e do, with the idea that a better understanding of the reasoning that fundamentally influenced the common idea of our expanding universe might help to resolve some of the sign ifica t problems that modern cosmology now faces; and we eventually use this knowledge to probe the foundations of the standard model. Much of the information we present, includi ng many of the historical details, we expect will be news to modern practitioners.
Content table Executive summary 02 Introduction 03 Literature review 04 Empirical results I : market-level analysis 06 Empirical results II : firm-level analysis 17 Conclusion

Dr. Alexey Akimov is a Lecturer in Finance at University of Lancaster. He joined Lancaster in 2012 following the completion of his PhD from the University of Reading. His research covers areas such as interest rate sensitivity & monetary shocks; commonalities in asset cycles and inflation forecasting. Dr. Chyi Lin Lee is a Senior Lecturer in Property at University of Western Sydney. He has published more than 20 papers on a variety of topics relating to property investment and finance. He received his PhD from the University of Melbourne. Professor Simon Stevenson is Professor of Real Estate Finance & Investment at the Henley Business School, University of Reading. He has published over 70 papers in a variety of leading real estate and finance journals. His primary research interests are in listed real estate; housing economics; investment modelling & portfolio management and international financial markets. The sensitivity of European publically-listed real estate to interest rates
ASSESSMENT OF THE DIAGNOSTIC VALUE OF THE METHOD OF COMPUTER OLFACTOMETRY

Olfactory studies can be a criterion for evaluating rhinosurgical intervention, and olfactory impairment may indicate respiratory impairment. Therefore, the urgent task is to develop an integrated approach to determining respiratory and olfactory disorders. A structural scheme was developed for the method of objective diagnosis of respiratory and olfactory disorders, taking into account the measu, rement of both the aerodynamic parameters of nasal breathing and the calculation of energy characteristics, which are used to determine olfactory sensitivity. The diagnostic significance of the proposed method of analyzing rhinofolipometry data with regard to additional parameters was assessed - it is necessary to take into account the time and power of breathing when the threshold of sensation of the odorivector is at the transition point of the airflow mode to the turbulent quadratic. It has been established that it is advisable to use the energy criteria of nasal breathing, pneumatic power and energy of nasal breathing under the action of the corresponding odor vector for the assessment of respiratory impaired olfactory. To assess the respiratory impairment of olfactory, it is necessary to use the method in which an odor vector is installed in the air path of the rhinomanometer, and the patient is asked to perform breathing maneuvers with a consistent increase in respiration rate while fixing the time at which olfactory sensitivity is achieved and then determining the respiratory energy characteristics. A statistical processing of diagnostic results was carried out, which confirms the adequacy of the model of independent statistical verification and makes it possible to use this method for the functional diagnosis of respiratory-olfactory disorders and testing of respiratory-olfactory sensitivity. The probability index of the error of the second kind is 0.17.
Clinical Profile in Hypokalemic Periodic Paralysis Cases

The present article was aimed to study demographic and clinical pattern, periodicity and precipitating events for hypokalemic paralysis and to assess the response to treatment both during acute attacks and as prophylaxis in comparison with available literature. Forty patients with hypokalemic paralysis were admitted in Narayana Medical College and Hospital during the last two years, in all the medical units and neurology wards. Patients were assessed clinically, with symptomatology and precipitating factors were evaluated. There were total 40 patients in the present study. Younger more including male gender. Mean age was 30.95 years. Common precipitating factor were diarrhea, fever, strenuous activity, following dextrose administration, in patients with diabetic ketoacidosis, however in majority of the cases we could not identify the precipitating factors. Most common electrocardiographic change on ECG was U' wave (36 cases) followed by flat 'T' wave (14 patients) and ECG was normal in 4 patients. Hypokalemic paralysis was predominantly seen in younger males. Vomiting, diarrhea were important precipitating factors. The response to oral potassium chloride supplementation was good as only few patients requiring intravenous potassium chloride. The approach to hypokalemic paralysis patient includes a vigorous search for the underlying etiology and potassium replacement therapy.
Design and optimization of a microfluidic chip for single cell analysis of circulating tumor cells

Breast cancer remains one of the leading causes of death in woman. The prognosis of cancer patients is predominantly influenced by the formation of metastases, with 10 to 15% of patients developing distant metastases within 3 years of primary tumour detection. Tumour cells with epithelial origin circulating in the peripheral blood are called circulating tumour cells (CTCs). Breast cancer therapeutic decisions are based on tumour markers such as ER, PR and HER2 which makes tumour cells characterization extremely important. Cancer progression is normally monitored by biopsy, an invasive procedure not well accepted in the clinic nor by the patient. An alternative approach is to analyse a blood sample, liquid biopsies are minimally invasive and they can be done repeatedly, allowing for real-time monitoring of the cancer evolution. The development of cheap, fast and reliable devices capable of isolating and characterizing CTCs is urgent. In this thesis, a microfluidic device to purify and analyze CTCs is reported. It was proved that this device can isolate MCF-7 and SKBR3 cells with an average trapping efficiency of 98% (N=9) with the cells remaining viable. It was also proved that it is possible to perform single cell analysis. Immunocytochemistry was done to characterize the phenotype of CTCs by targeting membrane receptors. The possibility to perform fast phenotypic characterization of CTCs with this microfluidic device has the potential to vastly improve the monitoring of cancer treatment and, in some cases, lead to therapeutic changes that can profoundly impact patient prognostic.
Where the standard makes the difference in the real world of malnutrition: Analysis of 10 countries with DHS data.

The 1977 International Growth Reference formulated by the National Center for Health Statistics (NCHS) and endorsed by World Health Organization (WHO) has long been used to assess the nutritional status of children. In 2006 however WHO introduced new Child Growth Standards to replace the 1977 NCHS Reference. The study reported here presents findings from 10 DHS surveys representing countries in South Asia Central Asia sub-Saharan Africa and South America to compare the prevalence of stunting wasting underweight and overweight in children under age 5 years by these two international standards. Using the 2006 WHO Standards increases the prevalence of stunting wasting and overweight among children while the prevalence of underweight children is lower compared with using the 1977 NCHS Reference. After controlling for various background characteristics of children the study finds that place of residence (rural versus urban) and birth order are the only two characteristics that seem not to be important predictors of differences in stunting and wasting respectively between the 1977 NCHS Reference and the 2006 WHO Standards. Most findings of our study agree with findings from other studies reported in the literature. These findings have implications for evaluating children’s nutritional status and for analyzing trends. Our major conclusion is that malnutrition tabulations should be made using both the 1977 NCHS Reference and the 2006 WHO Standards during the transition between the former reference and the new standards.
Standardization of organic seed priming techniques in Garden Sage (Salvia officinalis L.)

Sage (Salvia officinalis L.) is an important medicinal and aromatic herb, used as a raw material for various perfumery, pharmaceutical, food and cosmetics industries. However in sage, seed germination is a problem of great concern, as the germination percentage is less than 50 % due to dormancy, resulting lack of synchronized crop establishment. Hence an investigation was carried out to break the seed dormancy for uniform and early seed germination by using low cost organic seed priming techniques. Ten pre-sowing organic seed treatments were imposed by using locally available resources such as; water soaking (cold and hot), cow urine (5, 10, 15 and 20 %), cow dung slurry, buttermilk, compost tea and Agnihotra ash along with an untreated control. Among the different treatments, seed germination percentage was significantly high (79.67) in cow dung slurry treatment followed by cow urine at 5 per cent (72.33) as compared to control (35.33 %). Cow dung slurry treatment also recorded uniform and early germination (6 days for initiation and completed in 10 days) with significantly high rate of germination (22.14). Number of leaves, shoot length, root length and seedling vigour index was also recorded maximum in cow dung treated seeds followed by cow urine (5 %), hot water and cold water soaking treatments. Citation: Sharma Y. , Thimmaiah A. , Schaefer J. and John F. , 2018. Standardization of organic seed priming techniques in Garden Sage (Salvia officinalis L.). International Journal of Medicinal Plants. Photon
DDDT_A_215433 3105..3116

Li Zhang Jingwen Huang Ran Dong Yun Feng Min Zhou 1Department of Respiratory and Critical Care Medicine, Shanghai Institute of Respiratory Disease, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Institute of Respiratory Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 3Department of Respiratory Medicine, Tongji Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China Purpose: Leukotriene B4 (LTB4) is a major pro-inflammatory mediator that leads to the persistence of chronic inflammation in chronic obstructive pulmonary disease (COPD). The purpose of this study was to evaluate therapeutic potential of BLT1 antagonist for cigarette smoke (CS)-induced COPD and to explore the underlying mechanism. Materials and methods: In vitro, autophagy proteins were determined by Western blotting in RAW264.7 macrophages treated with U75302 (BLT1 antagonist) or autophagy inhibitor in cigarette smoke extract-induced inflammation. In vivo, C57BL/6J mice were randomly divided into three groups: Control group, CS group and CS+U75302 group. After 12-week exposure, histological analysis and lung function tests were performed to evaluate the inflammatory infiltration and emphysema. The expression of inflammatory cytokines was measured by real-time PCR and enzyme-linked immunosorbent assay. Immunohistochemical analysis and Western blotting detected the expression of autophagy-related proteins. Transmission electron microscopy (TEM) showed the alterations of autophagosomes and lysosomes. Results: Lower levels of inflammatory factors and autophagy markers were detected in U75302-treated cells and mice after CS exposure than control. In vitro, LC3 mRNA expression was elevated when treated with U75302. Autophagy inhibition resulted in augmented inflammatory response and autophagy proteins even with U75302 treatment. Furthermore, BLT1 antagonist decreased the number of lysosomes and autophagosomes in alveolar macrophages of mice and potentially enhanced the expression of transcriptional activation of transcription factor-EB (TFEB) in vitro and vivo. Conclusion: Insufficient autophagy of macrophages was associated with LTB4-mediated inflammation in CS-exposure models. BLT1 antagonist ameliorated inflammatory response through inducing autophagy.
5 Distinctively human thinking: modular precursors and components

This chapter takes up, and sketches an answer to, the main challenge facing massively modular theories of the architecture of the human mind. This is to account for the distinctively flexible, non-domain-specific, character of much human thinking. I shall show how the appearance of a modular language faculty within an evolving modular architecture might have led to these distinctive features of human thinking with only minor further additions and non-domain-specific adaptations.
Tolerability and incidence of infusion site reactions with emulsion formulation of vinorelbine (ANX-530) compared to vinorelbine solution

13549 Background: ANX-530 is an oil-in-water emulsion formulation of vinorelbine that has demonstrated less vein irritation, equivalent antitumor activity, and similar pharmacokinetic profiles to vinorelbine solution in preclinical studies. Pharmacokinetic equivalence to vinorelbine solution was recently reported in patients treated with each agent in a randomized clinical study. Methods: Thirty-one patients were enrolled in this single-dose 2-period crossover study, randomized for sequence. Patients had an advanced cancer potentially sensitive to vinorelbine after failure of standard treatments. Patients were randomly assigned to receive a single intravenous dose of either ANX-530 or vinorelbine in the first study period, then 1 week later, were crossed over to the other vinorelbine formulation. Both drugs were infused over 10 minutes at a dose of 30 mg/m2 using a calibrated syringe pump. Adverse events were analyzed by a logistic regression model with factors for treatment (ANX-530 vs. vinorelbine), per.
Economic Inter-Municipal Disparities in the Hradec Kralove Region of the Czech Republic

Municipal budgets are very important factors for the quality of fulfillment of obligatory and facultative tasks of municipality councils and managers to retain sustainable development of municipalities. In this work we have studied the range of disparities in economy and finances per hectare of the cadastral area per capita of the municipalities in the Hradec Kralove NUTS III Region in span of time 2001-2009. The total incomes per hectare and capita in the Hradec Kralove NUTS III Region ranged from 17 to 2532 CZK 2 , median was 158 CZK. The assets per hectare per capita (at Jan 1st 2009) ranged from 11 CZK to 2276 CZK, median value was 133 CZK. Disparities among the municipalities and towns related per hectare of the cadastral area per capita were significantly higher than those per capita, but of the same range as those per hectare of the cadastral area, respectively, we had found earlier. The inter-municipal disparities have been often met in the same micro-region, i.e. in the same outer economic, political, social, etc. environment. Key-Words: Economy, Finances, Budget, Incomes, Expenses, Municipalities, Disparities, Management 1 The contribution was created in the frame of the WD-48-07-1 Project of the Ministry of the Local Development of the Czech Republic 2 Currency ratios (at Dec 31 2009) were 26.465 CZK/€, 29.798 CZK/GBP, 19.875 CZK/100 JPY, and 18.368 CZK/USD.
A Comparative Study on Antimicrobial Activity in Different Varieties of Bangladeshi Citrus Species

Fruit peels are major byproduct of processing food and are not currently used commercially, but it can be a potential antimicrobial agent. As microorganism resistance to marketed antibiotics is prime concern now a day, the study concentrated on potential antibacterial activity of the following citrus species grown in Bangladesh. The purpose of the present study is to evaluate the peel of ten Bangladeshi citrus species namely C. maxima (local name, Batabilebu), C. reticulate (local name, Khasikomla), C. medica (local name, Jaralebu), C. sinensis (local name, Malta), C. lemon (local name, Lebu), C. hystrix (local name, Satkora), C. assamensis (local name, Adalebu), C. limittoids (local name, Sorbotilebu), C. aurantium (local name, Karuljamir), C. meyeri (local name, Chinalebu) against gram-positive and gram-negative bacteria such as Escherchia coli, Bacillus cereus, Streptococcus aureus, Shigella dysenteriae and Shigella sonnei. The disc diffusion method was used to evaluate the inhibition zones of bacterial growth and the results were compared with kanamycin, a commercial antibacterial agent. The C. limittoids peel of petroleum ether extract and C. aurantium peel of methanol extract exerted the highest antibacterial activity which exceeded the standard antibiotic kanamycin. Although higher antibacterial effects were observed in petroleum ether fraction however the effects were assumed to be much potent and predominant for methanol extract of peel. Our findings may explore new uses of peel and demonstrate that the C. aurantium peel of methanol extract is the best candidate among all because of its higher specificity to the microorganisms.
Effects of Brand Feedback to Negative eWOM on Attitude Toward the Product

Brands often provide a response, or brand feedback, to negative online reviews or electronic word-of-mouth (eWOM). The current research investigates whether brand feedback to negative eWOM by reviewers can impact information processing of visiting consumers who read the negative eWOM to make a purchase decision, particularly on the consumers’ attitude toward the featured product. Results from a 2 (Brand Feedback: Present/Absent) X 2 (Products: Laptop/TV) between-subjects experiment show the presence of brand feedback may have implications for consumers’ information processing online. Although the effects found were not very strong, the findings nevertheless did give some indications brand feedback to negative eWOM can affect consumer’s attitude toward the featured product. The study tends to support the usefulness of a dynamic (two or multi-way information flow between reviewers, brands, other consumers) rather than static (one-way information flow from reviewers to others) conceptualization of eWOM that allows for brands’ participation.
Inertia compensation for perturbations on instrumented treadmills

Instrumented treadmills and perturbations of the treadmill are commonly used for gait analysis and can provide real time biomechanical information and feedback of gait patterns and abnormalities. Force plates in the treadmill are combined with motion capture data and fed into a musculoskeletal model. High accuracy of the force plates is needed to give reliable feedback for gait analysis. The accuracy still needs to be tested under dynamic conditions, with the belt running. Also, inertial and gravitational forces are measured during perturbations as a result of the rotation and translation of the platform in which the force plates are positioned. This results in an error in the forces and moments as measured by the force plates, which is added up to the forces exerted by a subject. Inertia compensation models have been developed and showed promising results but have not been validated extensively. This study aimed to optimize and validate an inertia compensation model for perturbations on instrumented treadmills and validate the force measurements under dynamic conditions. It was shown that the treadmill can accurately measure the center of pressure (error = 1-6 mm), forces (error = 1-7 N) and moments (error = 0.5-4 Nm). A new calibration trial was found with higher sway accelerations which improved the inertia compensation model and left residuals forces and moments below 2 N(m). Moreover, it showed that using this inertia compensation model for pitch and sway trials led to a reduction of the kinetic residuals of up to 96% and values close to baseline measurements.
INCIDENCE OF RICE HISPA, DICLADISPA ARMIGERA (CHRYSOMELIDAE: COLEOPTERA) ON SUGARCANE CROP AND ITS CHEMICAL CONTROL

The seasonality of infestation pest and population dynamics of Dicladispa armigera (Chrysomelidae: Coleoptera) commonly known as Rice Hispa were studied at Paroka experimental farm, University of Agriculture, Faisalabad, Pakistan in two consecutive years 2010-2011 on February and September season crops of sugarcane, respectively. A trial was also carried out during 2012 to find out the most effective insecticide against the pest. The results showed that peak population level of the pest (6-7 adults/sweep) was found in June during both years (2010 and 2011). The pest was absent in sweeps from November to January. Pest population in February and September crop was 2.611±0.543 and 1.944±0.383 per sweep, respectively. Damaged leaf area was higher in the months of June-September ranging from 30-70 percent in February crop and 10-35 percent in September crop. Temperature was the most important factor that favored the population with r =0.4375 to 0.7784. Damaged leaf area was highly significantly correlated with adult population in both season crops with r =0.8804 and r =0.7731, respectively. Percentage reduction of adult population was found maximum (94%) in the chlorpyrifos treatment showing rapid knockdown effects followed by acetamiprid (70%) and fenpropathrin (58.5%). Minimum of damaged leaf area and higher yields were also recorded in chlorpyrifos (6.2% and 81 kg/plot) and acetamiprid (7.26% and 74 kg/plot)