Miracle-dz/UniFAR-FTUs huggingface dataset:
Estimation of Three-Phase Induction Motor Equivalent Circuit Parameters from Manufacturer Catalog Data

The single phase equivalent circuit is largely used to model the three-phase induction motors in steady-state operation and under sinusoidal balanced voltages. Depending on the desired application, the circuit may or may not represent core losses, a double cage or even the variation of parameters due to skin effect and saturation. However, the determination of the circuit parameters through standard methods, such as those described in IEEEÂ Standard 112, may not be possible in many situations given the lack of the necessary resources. This paper presents initially a survey on the determination of circuit parameters from alternative methods, i.e., non-standard tests. Special focus is given to methods which employ only data usually provided by manufacturers on catalogs and nameplates. Six analytical methodologies used in the context of efficiency estimation at steady-state operation are assessed, compared and then combined in order to improve results. The assessment is based on the closeness of the resulting parameter values to reference values and on the inexistence of absurd results, such as negative electrical resistances. The combination of methods has improved the accuracy of calculations for the studied motors.
Addition, deletion, and substitution of long nonhomologous deoxyribonucleic acid segments by genetic transformation of Haemophilus influenzae

A complete EcoRI digest of Haemophilus influenzae phage HP1 deoxyribonucleic acid (DNA) was mixed with incomplete digests of various H. influenzae R plasmids, sealed with T4 ligase, and transformed into an HP1 lysogen. Most of the chloramphenicol- and tetracycline-resistant transformants did not produce phage although they possessed all the phage genes examined. They also did not transfer antibiotic resistance by conjugation. DNA lysates from them transformed other lysogens to resistance and to loss of phage production at different but quite high frequencies (addition of long DNA segments). They themselves could be transformed efficiently to strains with a wild prophage (deletion of long DNA segments). It was concluded that lysogenic cultures had been constructed with various DNA inserts in their prophages carrying antibiotic resistance genes from the R plasmids. The site of insertion was determined by genetic crosses. DNAs with inserts that transferred with lower efficiency were more sensitive to ultraviolet radiation. This supports the view that insert transfer efficiencies reflect the sizes of the insert.
Environmental Mimics and the Lvh Type IVA Secretion System Contribute to Virulence-Related Phenotypes of Legionella pneumophila

ABSTRACT Legionella pneumophila, the causative organism of Legionnaires' disease, is a fresh-water bacterium and intracellular parasite of amoebae. This study examined the effects of incubation in water and amoeba encystment on L. pneumophila strain JR32 and null mutants in dot/icm genes encoding a type IVB secretion system required for entry, delayed acidification of L. pneumophila-containing phagosomes, and intracellular multiplication when stationary-phase bacteria infect amoebae and macrophages. Following incubation of stationary-phase cultures in water, mutants in dotA and dotB, essential for function of the type IVB secretion system, exhibited entry and delay of phagosome acidification comparable to that of strain JR32. Following encystment in Acanthamoeba castellanii and reversion of cysts to amoeba trophozoites, dotA and dotB mutants exhibited intracellular multiplication in amoebae. The L. pneumophila Lvh locus, encoding a type IVA secretion system homologous to that in Agrobacterium tumefaciens, was required for restoration of entry and intracellular multiplication in dot/icm mutants following incubation in water and amoeba encystment and was required for delay of phagosome acidification in strain JR32. These data support a model in which the Dot/Icm type IVB secretion system is conditionally rather than absolutely required for L. pneumophila virulence-related phenotypes. The data suggest that the Lvh type IVA secretion system, previously thought to be dispensable, is involved in virulence-related phenotypes under conditions mimicking the spread of Legionnaires' disease from environmental niches. Since environmental amoebae are implicated as reservoirs for an increasing number of environmental pathogens and for drug-resistant bacteria, the environmental mimics developed here may be useful in virulence studies of other pathogens.
Recurrent presence of the PLCG1 S345F mutation in nodal peripheral T-cell lymphomas

Peripheral T-cell lymphomas (PTCLs) are a group of non-Hodgkin lymphomas (NHLs) with heterogeneous clinical presentation, histology, response to treatment and outcome, whose genetic background is still poorly understood. Patients with PTCL are usually treated with CHOP or more intensive regimens,
Managing pathologic aggression in people with psychotic disorders.

A 55-year-old man had longstanding paranoid beliefs that the police were responsible for his personal bankruptcy. He believed they wanted to kill him through actual or simulated suicide, and he often carried a revolver. After attempting suicide by firearm, delusional disorder and major depression were diagnosed and he started risperidone and citalopram. A few years later, he shot 5 people, killing 1. He believed he saw police officers at his former company and believed they were conspiring to kill him.
Initiation of DNA-dependent RNA synthesis and the effect of heparin on RNA polymerase.

The kinetics of RNA synthesis, catalyzed by DNA-dependent RNA polymerase from Escherichia coli, show a lag phase at high ionic strength or at low temperature when using a double-stranded DNA as template. This lag phase increases with decreasing temperature at constant ionic strength or with increasing ionic strength at constant temperature. With single-stranded DNA as template, no lag phase is observed. The length of the lag phase is greatly shortened by pre-incubation of the enzyme with DNA at low Mg++ concentration, independent of the presence of substrate. Heparin is a strong inhibitor of free and DNA-bound polymerase. Two heparin molecules are required for the inactivation of one enzyme molecule. Enzyme engaged in RNA synthesis is instantly inhibited on single-stranded DNA but not on double-stranded DNA. With the aid of this inhibitor it is shown that 10 minutes after the start of incubation, at 16°, all enzyme molecules have initiated RNA chains on double-stranded DNA.
Relaxant effects on tracheal and ileal smooth muscles of the guinea pig.

The effects of volatile oils of 22 plants from 11 different families and of some of their constituents on tracheal and ileal smooth muscles were investigated. The results were compared with the relaxant effects of catecholamines and phosphodiesterase inhibitors. All of the oils had relaxant effects on the tracheal smooth muscle, the most potent were angelica root, clove, elecampane root, basil and balm leaves oil. 16 oils inhibited the phasic contractions of the ileal myenteric plexus-longitudinal muscle preparation, the most potent were elecampane root, clove, thyme, balm leaves and angelica root oil. 2 oils (anise and fennel) increased the phasic contractions, and 4 oils (bitter orange, caraway, mace, pepper) produced a marked increase in resting force (i.e. contracture). In regard to the relaxant effects, most of the 16 oils were more potent on the ileal than on the tracheal muscle. However, a small group of 4 oils (angelica root, clove, basil, black caraway) had a higher relaxant effect on the tracheal than on the ileal muscle. This was also found to be the case with eugenol, eugenol acetate and cinnamic aldehyde as well as with isoprenaline and phosphodiesterase inhibitors.
ei24, a p53 Response Gene Involved in Growth Suppression and Apoptosis

ABSTRACT DNA damage and/or hyperproliferative signals activate the wild-type p53 tumor suppressor protein, which induces a G1 cell cycle arrest or apoptosis. Although the mechanism of p53-mediated cell cycle arrest is fairly well defined, the p53-dependent pathway regulating apoptosis is poorly understood. Here we report the functional characterization of murine ei24 (also known asPIG8), a gene directly regulated by p53, whose overexpression negatively controls cell growth and induces apoptotic cell death. Ectopic ei24 expression markedly inhibits cell colony formation, induces the morphological features of apoptosis, and reduces the number of β-galactosidase-marked cells, which is efficiently blocked by coexpression of Bcl-XL. Theei24/PIG8 gene is localized on human chromosome 11q23, a region frequently altered in human cancers. These results suggest that ei24 may play an important role in negative cell growth control by functioning as an apoptotic effector of p53 tumor suppressor activities.
Pengaruh Profitabilitas, Financial Leverage, Dan Harga Saham Terhadap Praktek Perataan Laba Pada Perusahaan Manufaktur Yang Terdaftar Di Bursa Efek Indonesia

This study aimed to examine (1) the effect of profitability on income smoothing practices, (2) the effect of financial leverage on income smoothing practices and (3) the effect of stock price to income smoothing practices in companies listed on the Indonesia Stock Exchange. This study is classified as a type of research that is causative. This study is a population of companies listed on the BEI 2008-2011. Samples was determined by purposive sampling method, a total of 41 companies. The data used in this study is a secondary data obtained from the Indonesian Capital Market Directory (ICMD). Techniques of data analysis using multiple linear regression statistical test F and test t. The results prove that: 1) no significant effect on the profitability of the practice of income smoothing, 2) financial leverage significant effect on income smoothing practices, 3) share price did not significantly influence the practice of income smoothing. In this study suggested: 1) For listed companies should improve performance, manage the company effectively and efficiently, so that it can achieve a good ROA, 2) For investors and users of financial statements should take to heart in decision making, 3) For similar studies in order can use the other independent variables that could be expected to provide income smoothing prediction model practice better. The financial statements, because it could have reported ROA look good, not necessarily depict the actual situation in which the information is useful. Keywords: profitability, financial leverage, stock price, earning management
Experimental Analysis of a Variable Capacity Heat Pump System Focusing on the Compressor and Inverter Loss Behavior

Capacity control with variable speed compressors in heat pump systems is one of the techniques having a potential for efficiency improvement in heat pump systems. It is anticipated that the compressor and inverter efficiency are influenced by changes of the compressor speed. The present experimental study evaluates these losses in a variable speed heat pump system. The experimental results show that increasing the compressor speed reduces the heat pump COP up to 30%. The inverter loss increases as the compressor speed is increased, although the inverter loss as the percentage of the total compressor power decreases. Increasing the compressor speed increases the pressure ratio from 2.7 to 5.8, increasing the loss due to the pressure ratio mismatch drastically. Finally, the highest total isentropic efficiency of the compressor is obtained when the compressor frequency is close to 50Hz.
DIVERGENT PATTERNS OF EXTRACELLULAR MATRIX PROTEIN EXPRESSION IN NEONATAL VERSUS ADULT LIVER FIBROSIS

The extracellular matrix (ECM) expression is subject to distinct changes during ontogeny, and the natural course of liver fibrosis in neonates is thought to differ from that in adults. We compared the expression and distribution of main ECM components between neonatal and adult liver fibrosis. Liver biopsies from infants with neonatal cholestasis and fibrosis were compared to adult biopsies exhibiting an equivalent stage of fibrosis. All biopsies were examined by immunohistochemistry (indirect ABC method) for the ECM proteins, collagens I, III, IV, and VI, laminin, and fibronectin. Infants (aged 1-8 months) with neonatal hepatitis (n=3), extrahepatic biliary atresia (EHBA) (n=5), and normal histology (n=2) were compared with 9 adults (aged 17-70 years) with chronic hepatitis (n=3), primary biliary cirrhosis (PBC) (n=4), and normal histology (n=2). Collagens I, III, and IV and fibronectin were significantly increased in neonatal hepatitis with mild fibrosis (score h 4) compared to adults with an equivalent fibrosis stage. This increase was particularly notable in perisinusoidal spaces. Laminin expression was increased in portal and perisinusoidal spaces both in neonatal hepatitis and extrahepatic biliary atresia with mild fibrosis. In infants with moderate to severe fibrosis (score S 6), only collagen I was increased in comparison to adults, whereas collagen VI expression was identical in all groups, irrespective of the degree of fibrosis. Expression of matrix proteins was not different in infants and adults without fibrosis. The increased perisinusoidal deposition of certain ECM components in infants with active hepatitis and mild fibrosis may point to an underlying difference in the mechanism or stimulus of fibrogenesis in neonates as compared to adults.
Single-resonator dual-frequency AIN-on-Si MEMS oscillators

This paper reports on the design, implementation, and phase-noise optimization of low-power interface IC for dual-frequency oscillators that utilize two high quality factor (Q) width-extensional bulk acoustic modes of the same AlN-on-silicon resonator. Two 0.5-μm CMOS transimpedance amplifiers (TIA) have been designed, characterized, and interfaced with two dual-mode resonators operating at 35.5/105.7 MHz (first/third order modes) and 35.5/174.9 MHz (first/ fifth order modes). One TIA uses open-loop regulated cascode (RGC) topology in the first stage to enable low power operation, whereas the second one uses an inverter with shunt-shunt feedback to deliver higher gain with lower phase noise. An on-chip switching network is incorporated into each TIA to change the oscillation frequency based on the different phase shift. The effect of TIA on the phase-noise performance of oscillators is studied and compared for both topologies. The measured phase noise of low- and high-frequency modes at 1 kHz offset from carrier are -114 and -108 dBc/Hz for the 35/105 MHz oscillator, and -108 and -105 dBc/Hz for the 35/175 MHz oscillator, respectively, whereas the far-from-carrier reaches below -140 dBc/Hz in all cases.
Effective heuristics for timing driven constructive placement

We present a novel approach to path-based timing driven constructive placement based on simple yet effective heuristics. A novel circuit model is proposed. We have extended an existing pad placement technique for sequential circuits, the results for which are compared to the existing work by using the TimberWolf placement package for cell placement. In cell placement, demonstrated in this paper for combinational circuits, we have extended the method of defining the region for locating a cell (window) to minimise the interconnect delay. The window region is determined by the paths in the circuit, and the cells are chosen from the critical path. The placement approach and its experimental results are presented in detail. We also show the results of a study on the effectiveness of using subsets of the paths in the circuit for timing driven placement. We believe that our work is the first to comprehensively address the issue of pad placement, and to study the effectiveness of using subsets of the paths in the circuit in timing driven placement. These techniques are being adapted for use in VLSI placement in an industrial environment.
Impact of IFRS adoption and corporate governance principles on transparency and disclosure: the case of Istanbul stock exchange

The beneficial consequences of reduction in asymmetric information through disclosure and the performance effects of International Financial Reporting Standards (IFRS) are well-established. However, whether disclosure quality indeed increases due to mandatory and voluntary regulation/best practices , such as the adoption of IFRS and Corporate Governance Principles is still an emprical question that hasn’t been directly tested. This paper tests this in an emerging market (EM where the infrastructure, dominant family ownership, and lax rules and implementation make it less likely for the disclosure quality effects to be observed. We show that Transparency & Disclosure (T&D) scores have improved during 2003-2005 in a sample of Istanbul Stock Exchange Index firmsand those who voluntarily adopted IFRS generally have significantly higher scores. However, the 2005 T&D scores for mandatory and voluntary adopters are not significantly different. Multivariate analysis shows that voluntary IFRS adoption, Corporate Governance (CG) principles, and mandatory IFRS adoption all increase financial disclosure and overall T&D scores. These findings should be of interest to researchers, policy makers, and regulators, especially in EMs that have recently started to adopt these best practices
The Effects of Internationalization on the Composition of Board of Directors : A Quantitative Study of Swedish Multinational Corporations

The number of multinational corporations (MNCs) has increased tremendously since the 1990s,as companies have started to act in a more global environment. This has resulted in moreintegration between economies, where companies have to adjust to this changing environment. Inthis paper, we study the impact of internationalization on nationality diversity in boards ofSwedish MNCs during the period 1994-2012. Our propositions suggest that board size, acompany’s degree of internationalization and country of origin are contributing factors that affecthow a board is composed. Our findings concluded that companies with a high degree ofinternationalization often are more nationality diverse and that Swedish companies havegradually increased the number of non-Swedes in their boards over time.
Exploring The Use Of Leading Management Practices In Enterprises

Numerous management practices have emerged in recent years in response to competitive pressures calling for improved enterprises’ working and behavior. Despite the relevance of this phenomenon there are limited research evidences about comprehensive comparison of several and contently different management practices as carriers of corresponding management ideas behind them. In this study we examine the frequencies, patterns, and key drivers of 25 most used management tools by managers and professionals in enterprises, as selected appearance form of management practices in enterprises. The results indicate that tools are used by managers significantly more frequently than by professionals, indicating significant differences in patterns of tool usage when comparing the two groups. Among the key drivers of tools’ use by managers, education dominantly influence on tools use, work experiences had only a minor impact, while organizational size does not significantly influence on tools use. For professionals only enterprise size significantly influences on usage of two tools, while the impact of education and working year on tools usage is not significant. The findings offers disseminate knowledge for improving enterprises working through use of management tools and strengthen the theoretical base necessary for future selection and utilization of tools in enterprises production management.
Mycobacterial Bacilli Are Metabolically Active during Chronic Tuberculosis in Murine Lungs: Insights from Genome-Wide Transcriptional Profiling

ABSTRACT Chronic tuberculosis represents a major health problem for one-third of the world's population today. A key question relevant to chronic tuberculosis is the physiological status of Mycobacterium tuberculosis during this important stage of infection. To examine the molecular bases of chronic tuberculosis and the role of host immunity in mycobacterial growth, we determined the mycobacterial transcriptional profiles during chronic and reactivation phases of murine tuberculosis using in vivo microarray analysis (IVMA). Following 28 days of aerosol infection, mycobacterial counts remained stable, although the bacilli were metabolically active with a 50% active transcriptome. The expression of genes involved in lipid and carbohydrate pathways was significantly enriched during the middle stage of chronic tuberculosis, suggesting a nutrient-rich microenvironment. A total of 137 genes were significantly regulated in mid-chronic tuberculosis (45 and 60 days) compared to an early stage (14 days) of infection. Additional sets of genes, including the virulence regulator virS, were up-regulated during the reactivation stage, indicating their possible roles in mycobacterial resurgence. Interestingly, a set of potential transcriptional regulators was significantly induced at the late stage of chronic tuberculosis. Bioinformatic analysis identified a large number of genes that could be regulated by one of the potential transcriptional regulators encoded by rv0348, including the sigF operon. Taken together, IVMA provided a better definition of the transcriptional machinery activated during chronic and reactivation stages of tuberculosis and identified a novel transcriptional regulator. A similar approach can be adopted to study key stages of intracellular pathogens.
The effects of relationship quality on export performance: A classification of small and medium‐sized Turkish exporting firms operating in single export‐market ventures

Purpose – The purpose of this paper was to empirically examine the effects of relationship quality between exporter and importer on export performance in Turkish firms, and further, how small and medium‐sized exporting firms are segmented based on quality of their relationship with importers.Design/methodology/approach – The paper includes Structural Equation Modeling and Cluster Analysis.Findings – The findings demonstrate that there is the positive impact of: information sharing on financial export performance and satisfaction with the export venture; long‐term orientation on financial export performance, strategic export performance and satisfaction with the export venture; and satisfaction with the relationship on financial performance, strategic performance and satisfaction with export venture. Three segments of firm are profiled such as “long‐term thinkers”, “dissatisfactioners” and “information keepers”. Research limitations/implications – The data incorporate only the view of one player (the export.