Miracle-dz/UniFAR-FTUs huggingface dataset:
Additional effects of bosentan in patients with idiopathic pulmonary arterial hypertension already treated with high-dose epoprostenol.

BACKGROUND Combination therapy has been proposed in treatment algorithms for idiopathic pulmonary arterial hypertension (IPAH), so the additional effects of bosentan in IPAH patients already treated with high-dose epoprostenol (EPO) was evaluated in the present study. METHODS AND RESULTS Bosentan (62.5 mg twice daily) was administered to 8 IPAH patients already being treated with high-dose EPO (average dose 99.6+/-43.4 ng . kg(-1) . min(-1)). Hemodynamics were assessed at baseline and at 2 days and then 1 year after the initiation of bosentan. Because a remarkable elevation of mixed venous oxygen saturation was observed at the initiation of bosentan, the dosage of EPO was reduced in 7 patients (from 99.6+/-43.4 to 82.8+/-31.3 ng . kg(-1) . min(-1), p<0.05). There was a significant decrease from the baseline value for systolic pulmonary artery pressure (80.1+/-19.3 to 66.8+/-16.5 mmHg, p<0.05). These effects were maintained for 1 year without progression of PAH in 6 patients whose condition had been stabilized at baseline. CONCLUSIONS The additional use of bosentan for IPAH patients whose condition has been stabilized by high-dose EPO is safe and effective.
Pembiayaan Syariah Pada USAha Mikro, Kecil, Dan Menengah Sektor Agribisnis Dengan Pola Kemitraan

The agribusiness sector faces many problems, mainly lack of capital. High risk anduncertainty characteristics of agribusiness cause financial institution willingness to financeagribusiness very low. By these characteristics, sharia financial institutions have a greatopportunity to finance agribusiness sector. The agribusiness sector need flexible finance mainlyin the term of profit and loss sharing. Integrated sharia agribusiness partnership (ISAP) is asolution to overcome capital constraint of agribusiness. ISAP is a partnership program which isinvolves large-scale enterprises as a nucleus, and small-scale enterprises as a plasm, and thesharia financial institutions as a financial lender in a cooperation agreement. The purposes ofISAP are to improve feasibility of plasm farmers businesses, to increase link and cooperationbetween nucleus enterprises and plasm farmers, and help the sharia financial institutions toprovide finance to micro, small and medium enterprises safely and efficiently.
Parents of Children With Diabetes: What Are They Worried About?

Parental worries, specific to having a child with diabetes, have been associated with poor diabetes control. This study addressed three questions relating to this issue: Does parental worry affect the metabolic control of the child with IDDM? What specific aspects of diabetes are the most worrisome to parents? Do these concerns change with the child's age and disease duration? Parents of 93 children with IDDM were given a modified version of the Diabetes Quality of Life measure to evaluate diahetes-specific worries. No correlation was found between parental worry and the child's metabolic control. Parents of younger children expressed the largest amount of worry, yet the kinds of things that parents were most concerned about were the same, regardless of age or duration of the child's disease.
The Impact Of Risk Management And Bank Size On Profitability Of Commercial Banking In Indonesia

The growth of credit in Indonesian Banking industry tends to be slower in period 2011 until 2016 whereas the credit growth only 7.87% compare to 10.4% in 2016. But based on the important role of the banking sector for economic development, the regulator should manage the risk of the credit in order to create a healthy and strong banking industry. According to Bank Indonesia regulation, one of the banking risks is the liquidity risk which BI stipulated two things in managing the bank’s risk that is CAR and NPL. Then this research aim to investigate whether CAR, NPL and Size will give an effect to the profitability of the bank. With the sample of 30 commercial banks that quoted from Indonesian Stock Exchange period 2011-2015 by applying panel data regression analysis, the research result showed that there is a positive and significant effect of CAR toward bank’s ROA. NPL had a negative but insignificant effect toward ROA. Firm size had a positive and significant effect toward ROA. It is more profitable to invest in a bigger bank with a high CAR and less NPL. It’s implied that it will be more profitable to invest in a bigger bank with a high CAR and less NPL. Even though, it is important to monitor their CAR and NPL level.
THE IMPACT OF BUSINESS CLIMATE ON THE FINANCIAL PERFORMANCE OF SMALL AND MEDIUM SIZE ENTERPRISES IN CAMEROON

This article had as objective to assess the impacts of business climate on the financial performance of small and medium size enterprises in Cameroon. Specifically, it had to assess the impacts of general infrastructure, access to financial credit as well as the modes of financial regulation on the financial performance of small and medium size enterprises in Cameroon. To attain this objective, we used of primary data collected directly from the field thanks to open questionnaires that were administered to both top and middle class managers of the small and medium size enterprises. A simple model developed by Gikonya (2011) was employed in the analysis of the collected information. In this model elements of business climate make up the independent variable and financial performance as the dependent variable. The Ordinary Least Square method (OLS) was used to test the relationship between the variables. The result obtain showed that there exist a positive relationship between business climate and the financial performance of small and medium size enterprises in Cameroon. This result suggest that small and medium size enterprises should constantly monitor the business climate and its constantly evolving components especially the development of general infrastructures and accessibility to credit facilities but should also consider other important factors such as modes of financial regulation, asset utilization, market part as well as life cycle of the enterprise as important determinants of the level of financial performance. Key words: Business climate, financial performance, small and medium size enterprises, financial profitability, turnover
Interpretation of the Appearances of the Small Pulmonary Blood Vessels in Animals

A study was made of the histology of the small pulmonary blood vessels in uninflated postmortem specimens from the monkey, dog, fox, mouse, rat, rabbit, squirrel, sheep, pig, cow, seal, kitten, eivet, and guinea pig. The small pulmonary arteries appeared unusually muscular compared to those of man, and the increased medial thickness was reminiscent of the medial hypertrophy found as an early change in the human lung in diseases asso ciated with pulmonary arterial hypertension. This suggests to us that the histological cri teria usually employed for grade 1 hyperten sive pulmonary vascular disease in man are invalid when applied to lung biopsies from animals used for experiments on the pulmo nary circulation. There is a sphincter-like arrangement of the muscle of the media of the muscular pulmonary arteries of the guinea pig. In the rat, mouse, and squirrel there is an extension of cardiac muscle along the larger intrapulmonary veins. Fibromuscu Ear prominences project into the vein lumen iii the cow and the pig.
Domestic biogas digester as a means of wood fuel consumption reduction in the rural households of Wondo Genet, Southern Ethiopia

Abstract This paper examines the role of biogas technology in saving wood and evaluates whether biogas digesters are likely to help reduce fuel wood consumption in the rural households of Wondo Genet, Southern Ethiopia. A household survey, oral interviews, key informant interviews and a field experiment were carried out on biogas user and non-user households. A multi-stage sampling technique was then applied to select 200 interviewees from biogas user and non-user households. The mean daily consumption of charcoal, firewood, agricultural residues and animal dung by the biogas users were estimated at 0.80, 4.07, 0.88 and 0.91 kg, respectively, while the mean daily charcoal, firewood, agricultural residues and animal dung consumption by non-biogas users were estimated at 1.20, 6.33, 1.38 and 0.98 kg, respectively. The annual charcoal and firewood consumption of the biogas users was estimated to be 288 kg and 1465.2 kg per household, respectively, whereas non-biogas users consume 432 kg charcoal and 2278.8 kg firewood per household each year. A paired t-test analysis indicated that there is a significant difference (P < 0.05) in the level of consumption of firewood, charcoal and agricultural residues between biogas user and non-user households. However, the amount of dung cake consumed did not show significance difference (p > 0.05) between these household types.
Mutation of NRT1.1 enhances ammonium/low pH-tolerance in Arabiopsis thaliana

NRT1.1 is a dual-affinity nitrate transporter and a nitrate sensor that plays a role in nitrate-dependent signaling pathway. Recently, it has been revealed that NRT1.1 mutants show enhanced tolerance to ammonium and/or low pH conditions in the absence of nitrate, which indicates a nitrate-independent function of NRT1.1. Detailed underlying mechanisms for the ammonium/low pH-tolerance of the NRT1.1 mutants will be revealed by paying attention to auxin behavior, phosphorylated status of NRT1.1 and other components related to the primary nitrate response and nitrate transport.
Price Limit Performance: Evidence from the Tokyo Stock Exchange

Price limit advocates claim that price limits decrease stock price volatility, counter overreaction, and do not interfere with trading activity. Conversely, price limit critics claim that price limits cause higher volatility levels on subsequent days (volatility spillover hypothesis), prevent prices from efficiently reaching their equilibrium level (delayed price discovery hypothesis), and interfere with trading due to limitations imposed by price limits (trading interference hypothesis). Empirical research does not provide conclusive support for either positions. We examine the Tokyo Stock Exchange price limit system to test these hypotheses. Our evidence supports all three hypotheses suggesting that price limits may be ineffective.
On the origin of the quasi‐perpendicular ion foreshock: Full‐particle simulations

Many space missions have already evidenced the existence of the ion foreshock region located upstream of the Earth's bow shock and populated by energetic backstreaming ions reflected by the shock front. In order to analyze this region, a curved shock is simulated with a 2‐D particle‐in‐cell (PIC) code. The analysis is presently restricted to the quasi‐perpendicular angular range defined by 45° ≤ θBn ≤ 90°. In agreement with experimental data, present results evidence two distinct ion populations backstreaming from the shock front along the interplanetary magnetic field: (i) the field‐aligned beam population (hereafter “FAB”) and (ii) the gyrophase bunched population (hereafter “GPB”) which differ from each other by their gyrotropic or non‐gyrotropic behavior, respectively. Excluded by a simulation time which is too short, ion instabilities pitch‐angle scattering cannot be the source of “GPB. ” Two new criteria are proposed to identify more precisely each population: their interaction time Δtint with the shock front and their downstream penetration depth. These criteria show that (i) the “FAB” population moves back and forth between the upstream edge of the shock front and the overshoot, and is characterized by a Δtint covering several upstream gyroperiods. (ii) In contrast, the “GPB” ions suffer a short interaction time (i.e., 1 < τci). We observe that the “FAB” ions may have different origins although all “GPB” ions seem to be produced by the electrostatic field built up at the shock and are emitted in a burst‐like mode rather than in continuous way.
Transistor operation of 30-nm gate-length EJ-MOSFETs

We have fabricated electrically variable shallow junction metal-oxide-silicon field-effect transistors (EJ-MOSFET's) to investigate transistor characteristics of ultrafine-gate MOSFET's. By using EB direct writing onto an ultrahigh-resolution negative resist (calixarene), we achieved a gate length of 32 nm for the first time. The short-channel effects were effectively suppressed by electrically induced ultrashallow source/drain regions, and the fabricated device exhibited normal transistor characteristics even in the 32-nm gate-length regime at room temperature: an ON/OFF current ratio of 10/sup 5/ and a cut-off current of 20 pA//spl mu/m.
Open Markov chain scheme models fed by second order stationary and non-stationary processes

• We introduce a schematic formalism for the time evolution of a random open population divided into classes. With a Markov chain model, allowing for population entrances, we consider the flow of incoming members modeled by a time series either ARIMA for the number of new incomings or SARMA for the residuals of a deterministic sigmoid type trend and we detail the time series structure of the elements in each class. A practical application to real data from a credit portfolio is presented. Key-Words: • Markov chains, Open Markov chain models, Second order processes, ARIMA, SARMA, Credit Risk. AMS Subject Classification: • 60J10, 91D99, 62M10, 91B8. 278 M.L. Esqúıvel, G.R. Guerreiro and J.M. Fernandes Open Markov Chain Scheme Models 279
Comparative study of consumers' knowledge and attitudes towards food safety and purchase intention of night market foods containing poultry in low and high food poisoning cases states

This study was conducted to compare the level of consumers’ knowledge and attitude towards food safety as well as consumers’ intention to purchase night market food precisely food containing poultry based on food hygiene practice of food handlers in two different states i.e. Selangor and Kuala Lumpur. Selangor represents a state with high food poisoning cases while Kuala Lumpur has low food poisoning cases. Two hundred night market consumers for each sampling location were approached. Data was statistically analyzed using SPSS program version 20.0. Generally, respondents’ knowledge of food safety score was significantly different for consumers in Kuala Lumpur (M=14.37, SD=3.75) and Selangor (M=15.10, SD=3.36), (t=2.107, df=429) at p<0.05. Analysis also showed that there were significant differences in the attitude score among consumers in Kuala Lumpur (M=4.71, SD=0.39) and Selangor (M=4.48, SD=0.28), (t=7.085, df=414) at p<0.05. Results revealed that consumers’ intention to purchase night market food in Selangor and Kuala Lumpur are statistically different depending on food handlers’ practices (e.g. tasting food using fingers and hand palm, wear nail polish, touch cooked food with bare hands and etc.) This empirical study served status of consumers’ knowledge, attitude and intention to purchase regarding food safety which could be applied to implement repeated food safety education programs to improve quality of life in local communities.
Shared risk factors for falls, incontinence, and functional dependence. Unifying the approach to geriatric syndromes.

OBJECTIVE To determine whether a set of factors representing impairments in multiple areas could be identified that predisposes to falling, incontinence, and functional dependence. DESIGN Population-based cohort with a 1-year follow-up. SETTING General community. PARTICIPANTS A total of 927 New Haven, Conn, residents, aged 72 years and older who completed the baseline and 1-year interviews. MAIN OUTCOME MEASURES At least one episode of urinary incontinence per week, at least two falls during the follow-up year, and dependence on human help for one or more basic activities of daily living. RESULTS At 1 year, urinary incontinence was reported by 16%, at least two falls by 10%, and functional dependence by 20% of participants. The four independent predisposing factors for the outcomes of incontinence, falling, and functional dependence included slow timed chair stands (lower extremity impairment), decreased arm strength (upper extremity impairment), decreased vision and hearing (sensory impairment), and either a high anxiety or depression score (affective impairment). There was a significant increase in each of incontinence, falling, and functional dependence as the number of these predisposing factors increased. For example, the proportion of participants experiencing functional dependence doubled (7% to 14% to 28% to 60%) (chi 2 = 119.8; P < .001) as the number of predisposing factors increased from zero to one to two at least three. CONCLUSIONS Our findings suggest that predisposition to geriatric syndromes and functional dependence may result when impairments in multiple domains compromise compensatory ability. It may be possible to restore compensatory ability and prevent or delay the onset of several geriatric syndromes and, perhaps, functional dependence by modifying a shared set of predisposing factors. Perhaps it is time to take a more unified approach to the geriatric syndromes and functional dependence.
THE IMPACT OF TECHNOLOGICAL INNOVATION ON BANK PERFORMANCE

This study examines the impact of technological innovation factors on the performance of Lebanese banks during an eight-year period (from 2010 to 2017). The research employed return on assets (ROA) and return on equity (ROE) as proxies to measure performance level. The technological innovation factors include internet banking, mobile banking, automated teller machines and investment in computer software. The technological innovation investment in automated teller machines (ATMs) and internet banking has positive impact on the performance of Lebanese banks. The results also reveal non-significant impact of mobile banking and investments in computer software on the performance of Lebanese banks.
Examining the relationship between audit committee effectiveness and audit fees: An empirical investigation on companies listed in the UAE financial markets

This study seeks to understand the relationship between audit committee effectiveness and audit fees. Prior literature suggests two perspectives to explain this relationship; the first is demand based whereas a positive relationship is expected, while the second is audit risk which propose a negative relationship between the two variables. In order to test the relationship between the two variables, data were collected from 64 companies listed in Abu Dhabi Securities Exchange and Dubai Financial Market. Univariate and multivariate analyses were conducted to test the hypotheses of the study. Results showed that audit committee effectiveness has a significant positive impact on audit fees. This result supports the demand based perspective to explain the relationship between audit committee effectiveness and audit fees. Also, a significant positive relationship is reported for number of meeting of audit committees and audit committee members financial expertise with audit fees.
The Influence of Some Antifungal Drugs on In Vitro Adherence of Candida albicans to Human Buccal Epithelial Cells

Summary: An in vitro adherence test with 10 Candida albicans strains to buccal epithelial cells (BEC) was performed in a medium with the following antifungal drugs: nystatin, amphotericin B, 5‐fluorocytosine, clotrimazole and ketoconazole. Simultaneously, an in vitro adherence test was made without drugs added, but the fungal cells had been previously treated with the same drugs. All antifungal drugs applied significantly inhibited the adherence of C. albicans to BEC (p < 0.01). Pretreatment of the fungi with drugs inhibited their adherence to BEC stronger than the addition of the drugs to the test medium. Subinhibitory doses of the drugs were less effective than therapeutic ones. The most effective inhibition of the adherence was obtained with 5‐fluorocytosine and ketoconazole, while nystatin turned out to be the least effective.
Alien bryozoans in the eastern Mediterranean Sea--new records from the coast of Lebanon.

The Levant Basin (SE Mediterranean) is the most exposed to the introduction of non-indigenous species. The current assessment of exotic bryozoans present along the coast of Lebanon has been completed by the recording of fourteen cheilostome species (one cryptogenic) collected by diving in 17 localities (2-42 m). This set of exotic bryozoans comprises ten genera, including four (Akatopora Davis, 1934, Drepanophora Harmer, 1957, Mucropetraliella Stach, 1936 and Predanophora Tilbrook, 2006) not previously reported in the Mediterranean, while Celleporaria is the most successful extra-Mediterranean genus with four species in the survey collection. A new Celleporina species, C. bitari n. sp. , also collected in the Red Sea, is described. Although lessepsian migration through the Suez Canal is the main pathway for exotic bryozoans in this region, the geographic origin of some species suggests that shipping through Gibraltar Strait is also responsible to a large extent.
The relationship between employee turnover and customer service quality in casino restaurants

The Relationship between Employee Turnover and Customer Service Quality in Casino Restaurants by Karl D. Brandmeir Dr. Seyhmus Baloglu, Examination Committee Chair Assistant Professor o f Tourism and Conventions University o f Nevada, Las Vegas This study investigates the relationship between employee turnover and perceived service quality in casino restaurants. The restaurants were buffets, steakliouses, and coffee shops in casinos in three geographic locations. The study uses both cross-sectional and time-series data in a linkage model. It then analyzes the nature of this relationship on both a concurrent and consecutive periods over ten months. The data were analyzed with descriptive statistics, one-way ANOVA with Scheffe Post-Hoc tests, Pearson’s product moment correlations. Hypotheses were tested by correlations and time-lagged correlations. The results show that steakhouses have the lowest turnover and the lowest poor and failure ratings by customers. Buffet restaurants had the highest mean scores for waittime-to-be-seated. Front-of-the-House turnover has a strong correlation to customer service quality. The correlations and time-lagged correlations showed that employee