Miracle-dz/UniFAR-FTUs huggingface dataset:
Crevasse patterns and the strain-rate tensor: a high-resolution comparison

Abstract Values of the strain-rate tensor represented at a 20 m length scale are found to explain the pattern and orientation of crevasses in a 0.13 km2 reach of Worthington Glacier, Alaska, U.S.A. The flow field of the reach is constructed from surveyed displacements of 110 markers spaced 20-30 m apart. A velocity gradient method is then used to calculate values of the principal strain-rate axes at the nodes of a 20 m x 20 m orthogonal grid. Crevasses in the study reach are of two types, splaying and transverse, and are everywhere normal to the trajectories of greatest (most tensile) principal strain rate. Splaying crevasses exist where the longitudinal strain rate ( x ) is ≤ 0 and transverse crevasses are present under longitudinally extending flow (i.e. x > 0). The orientation of crevasses changes in the down-glacier direction, but the calculated rotation by the flow field does not account for this change in orientation. Observations suggest that individual crevasses represent local values of the regional flow field and are transient on the time-scale of 1-2 years; they are not persistent features that are translated and rotated by flow. Crevasse patterns are thus found to be a useful tool for mapping the strain-rate tensor in this reach of a temperate valley glacier.
Integration of functions dedicated to the mechanical solicitation and characterization of biological cells in microfluidic devices

This thesis aims at evaluating two different techniques for the distinction of mechanically impaired biological samples. Both approaches were developed and investigated keeping in mind the long term objective which is the application of these approaches to diagnosis based on cell mechanical phenotype. Although, we developed these approaches on Red Blood Cells as as their mechanical properties can be affected by important pathologies, all the concepts developed in this work can be adapted to other cell types.We characterized mechanically RBCs using a passive microfluidic technique. We focused on the shape relaxation of healthy Red Blood Cells (hRBCs) flowing out of an oscillating width channel and demonstrated the dependency of their mechanical response upon the experimental conditions. We reported the existence of two relaxation modes for RBCs depending on the flow parameters, we used the interface between the two modes to extract the mechanical properties of RBC.Using a second approach, we presented the results obtained during the study of the mechanical behavior of hRBCs using electrodeformation assays. We investigated the influence of the solicitation parameters on the cell response and concluded on optimized conditions for cell solicitation without altering them. Finally, we evaluated both techniques in the discrimination of rigidified samples from healthy couterparts. Advantages and drawbacks of both techniques were discussed
Applicability of Keller’s brand equity model in the B2B chemical market

A B2B (business-to-business) brand is a distinctive identity that differentiates a relevant, enduring and credible promise of value associated with a product, service or organisation, as well as indicating the source of that promise. The concept of B2B brand equity is one of the most intriguing concepts connected to B2B brands. Although there have been some attempts to conceptualise and measure B2B brand equity in the literature, in practice no consensus about the concept has been reached so far. Unlike previous studies, this study examines the applicability of Keller’s brand equity model in a specific industry and market – the B2B chemical market. For that purpose, a series of semi-structured face-to-face interviews were conducted with buyers of specific industrial chemical products in the South and Eastern European B2B chemical market. The results show that the Keller’s brand equity model can be applicable in the B2B chemical market, however, the six brand building blocks – salience, performance, imagery, judgements, feelings and resonance – as well as subdimensions that assemble the blocks, need arrangements in different ways in order to meet the logic of the B2B marketing philosophy. As a result, the respondents perceive corporate brands to be more important than product brands. They also point to the significance of the relationship with sales representatives in building brand equity. At the top block of the pyramid respondents set partnership relations, and cooperation in developing solutions oriented towards improvement of customers’ production processes.
Hands On/Hands Off: Why Health Care Professionals Depend on Families but Keep Them at Arm's Length

In the theater the fictional Dr. Kelekian’s relief that he does not have to talk to family members about his patient’s cancer treatment draws uneasy laughter from the audience. Doctors, patients, and family members alike recognize the situation, even if hearing it so baldly expressed discomfits them. Why do physicians and other health care professionals, including lawyers and bioethicists, so often view families as “trouble”? And why do families so often see medical professionals as uncaring and uncommunicative? Presumably everyone wants the same goal—recovery or the best possible outcome for the patient. And yet trouble clearly exists. We do not see the problem as one of “dysfunctional families” or “callous doctors,” although there are undoubtedly many of each.
The Association Between Severe Nephropathy and Pheochromocytoma in the Male F344 Rat— The National Toxicology Program Experience

The possible correlation between the severity of chronic progressive glomerulonephropathy (CPN) and the incidence of adrenal pheochromocytoma was examined in selected studies of male Fischer 344 (F344) rats at the National Toxicology Program (NTP). The NTP historical control database was first examined in order to determine whether there was association between the severity of CPN and the occurrence of adrenal pheochromocytoma in unexposed animals. Following this analysis, the 125 most recent NTP studies conducted in F344 rats were examined in order to determine how frequently chemicals that cause increased severity of CPN showed an increased incidence of pheochromocytoma. Finally, we examined the association between the incidence of pheochromocytoma and the severity of CPN in those NTP studies with chemically related increased rates of pheochromocytoma. In control male F344 rats surviving beyond 21 mo, the incidence of adrenal pheochromocytoma was consistently higher in animals with more severe CPN. This association was significant (p < 0.05) both for 900 NTP inhalation study controls and 900 NTP feeding study controls. An association was not consistently observed when dosed groups were considered. Although 22% (28/125) of NTP studies reported a chemically related increased severity of CPN, only 3 of these reported a corresponding significant increase in the incidence of pheochromocytoma. Of 6 NTP studies that reported increased incidence of pheochromocytoma, animals with pheochromocytoma from 5 of those studies had some degree of increased severity of CPN. However, the estimated strength of the correlation with the severity of CPN varied from study to study and was often quite different from that indicated by an analysis of the more extensive NTP control databases. The possible correlation between the severity of CPN and the incidence of pheochromocytoma may influence interpretation of carcinogenic effects observed at this site.
Paired basic science and clinical problem‐based learning faculty teaching side by side: do students evaluate them differently?

Introduction Many studies have evaluated the desirability of expert versus non‐expert facilitators in problem‐based learning (PBL), but performance differences between basic science and clinical facilitators has been less studied. In a PBL course at our university, pairs of faculty facilitators (1 clinician, 1 basic scientist) were assigned to student groups to maximise integration of basic science with clinical science.
RADIATION-INDUCED GENOMIC INSTABILITY: RADIATION QUALITY AND DOSE RESPONSE

Abstract— Genomic instability is a term used to describe a phenomenon that results in the accumulation of multiple changes required to convert a stable genome of a normal cell to an unstable genome characteristic of a tumor. There has been considerable recent debate concerning the importance of genomic instability in human cancer and its temporal occurrence in the carcinogenic process. Radiation is capable of inducing genomic instability in mammalian cells and instability is thought to be the driving force responsible for radiation carcinogenesis. Genomic instability is characterized by a large collection of diverse endpoints that include large-scale chromosomal rearrangements and aberrations, amplification of genetic material, aneuploidy, micronucleus formation, microsatellite instability, and gene mutation. The capacity of radiation to induce genomic instability depends to a large extent on radiation quality or linear energy transfer (LET) and dose. There appears to be a low dose threshold effect with low LET, beyond which no additional genomic instability is induced. Low doses of both high and low LET radiation are capable of inducing this phenomenon. This report reviews data concerning dose rate effects of high and low LET radiation and their capacity to induce genomic instability assayed by chromosomal aberrations, delayed lethal mutations, micronuclei and apoptosis.
Social Responses to Conversational TV VUI: Apology and Voice

The study investigated whether apologetic synthetic gendered voices affect users' perception of an error-prone VUI. In a TV viewing task, participants interacted with the conversational TV, and executed eight menus in a 2 apologetic error message: yes vs. no by 2 voice gender by 2 subject gender gender balanced, between participants experiment. When participants encountered errors, the TV provided verbal error messages, with or without an apology. The results revealed significant two-way interaction effects of apology yes and voice gender male on perception of the TV, and the voice. Irrespective of gender, participants responded to a male voice more, when it offered apologies for errors. It is interpreted that the context in which genuineness of apology was regarded as important made participants perceive a male voice as being more trustworthy than a female voice. The participants seem to have applied gender stereotypical perceptions to gendered VUI, as they do to other humans.
Effect of different running modes on the morphological, biochemical, and mechanical properties of articular cartilage

Mechanical loading plays an important role not solely in cartilage development, but also in cartilage degeneration. Its adaptation behavior to mechanical loading has not been clearly delineated. The aim of the study was to examine the effect of different running modes (with different muscle contraction types) on morphological, biochemical, and mechanical properties of articular cartilage in the knee of growing rats. Thirty‐six female Sprague–Dawley rats were randomly assigned into a nonactive age‐matched control (AMC), level (LEVEL), and 20° downhill (DOWN) running group (n = 12 each). Running groups were trained on a treadmill for 30 min/day, 5 days/week for 6 weeks. Immunohistochemical staining and analysis of expression for collagen II, collagen IX, cartilage oligomeric matrix protein (COMP), and matrilin‐3, histomorphometry of femoral cartilage height and femoral COMP staining height, and indentation testing of tibial articular cartilage were performed. Rats subjected to downhill running showed a significantly (P = 0.015) higher COMP staining height and a tendentially (P = 0.084) higher cartilage height in the high‐weight bearing area of femoral articular cartilage. Cartilage thickness, mechanical properties, and expression of cartilage network proteins in tibial cartilage remained unaffected by different running modes. Our data suggest that joint loading induced by eccentric muscle contractions during downhill running may lead to a site‐specific adaptation.
Selected semitransitive constructions in Algonquian

Abstract The present paper surveys a number of selected constructions in Algonquian languages that fall between those expressing transitivity and those expressing intransitivity (Hopper & Thompson 1980; Dryer 2007). Socalled passives are mostly agentless and show different kinds of allomorphy in the particular languages. Antipassives are not fully understood yet but seem to be more idiosyncratic than passives, and are not found everywhere in the family. Lastly, systematic mismatches between morphological and syntactic valency (similar to constructions found in Oceanic and other languages) seem to play an important role in the inventory of constructions used to express less than full transitivity in Algonquian.
Spatial Ultimatum Games, collaborations and the evolution of fairness

It is often the case that individuals in a social group can perform certain tasks (such as hunting, for example) more efficiently if they collaborate with other individuals than if they act alone. In such situations one is necessarily faced with the problem of how the resource obtained as the result of such a collaboration should be divided among the collaborating individuals. If one of the individuals in the collaboration is in a position (through its dominance rank, for example) to impose a particular division of the resource on the other members of the collaboration then we show that an evolutionary dilemma arises which prevents such collaborations being evolutionarily stable. This dilemma, which is closely related to the well–known Ultimatum Game, results from the fact that in such situations natural selection favours individuals who, if dominant, offer smaller and smaller shares of the resource to the others and, if subdominant, will accept lower and lower offers. We also show, however, that this dilemma is naturally resolved in a spatially structured population with selection favouring the evolution of a fair division of the resource and consequently ensuring the evolutionary stability of collaborations of this type.
Wine and Islam: the dichotomy between theory and practice in early Islamic history

The aim of this thesis is to demonstrate that the commonly held prohibition of alcohol did not prevent some members of the Muslim community from consuming intoxicating drinks. Specifically, this thesis will examine the consumption of wine in the Islamic world from the birth of the Prophet Muhammad (c. 570 ce) through the end of the reign of al-Ma'mun (218/833). Chapter 1 presents an overview of the presence and consumption of wine prior to the birth of Muhammad. It will be demonstrated that wine was a social and sometimes religious norm within the dominions that Islam was to dominate within a generation after Muhammad's death. Chapter 2 explores the prohibition of wine itself as revealed in the Qur'an and portrayed in hadlth literature. Chapter 3 examines the reigns of the Rashidun Caliphs and their efforts to come to terms with some parts of the community that were unwilling to cease drinking all forms of wine. Chapter 4 details evidence of continued wine consumption in the Umayyad Era and Chapter 5 similarly for the cAbbasid era with an overview of the development of the law with respect to the use of wine.
FOUR Forested Watersheds , Water Resources , and Ecosystem Services , with Examples from the United States , Panama , and Puerto Rico

Forested watersheds offer access to vital natural resources, i.e., water supply for drinking, agriculture and industry, transport routes, and hydroelectric energy. Ecosystem services provided by these watersheds are numerous and, in addition to good quality water, include reduced peak river flow during storms; increased availability of groundwater and base flow in streams during seasonal dry periods and droughts; reduced soil erosion and landslide probability; enhanced resilience to wildfire, pathogens, and invasive species; biodiversity; genetic resources; and recreation [1e3]. These resource and esthetic benefits come with risks associated with floods, landslides, and wildfires, which are episodic natural disturbances in these settings. Furthermore, these disturbances compromise the provision of the ecosystem services listed previously. Nonetheless, natural landscape disturbance by floods has well-known benefits, i.e., delivery of nutrients to flood plains; landslides open forest gaps that create small-scale opportunities for successional vegetation growth, while hurricanes and wildfires similarly serve as large-scale mechanisms for resetting landscapes and creating new habitats. More than half of the world population now lives in urban areas, which are expected to absorb all the population growth expected over the next four decades, mostly in the cities and towns of the less developed regions. The United Nations [4,5] has defined 23 megacities with at least 10 million inhabitants; all but 6 of these are in the developing world. These populations place large stresses on water and other resources.
An Autonomous Learning-Based Algorithm for Joint Channel and Power Level Selection by D2D Pairs in Heterogeneous Cellular Networks

We study the problem of autonomous operation of the device-to-device (D2D) pairs in a heterogeneous cellular network with multiple base stations (BSs). The spectrum bands of the BSs (that may overlap with each other) comprise the sets of orthogonal wireless channels. We consider the following spectrum usage scenarios: 1) the D2D pairs transmit over the dedicated frequency bands and 2) the D2D pairs operate on the shared cellular/D2D channels. The goal of each device pair is to jointly select the wireless channel and power level to maximize its reward, defined as the difference between the achieved throughput and the cost of power consumption, constrained by its minimum tolerable signal-to-interference-plus-noise ratio requirements. We formulate this problem as a stochastic non-cooperative game with multiple players (D2D pairs) where each player becomes a learning agent whose task is to learn its best strategy (based on the locally observed information) and develop a fully autonomous multi-agent Q-learning algorithm converging to a mixed-strategy Nash equilibrium. The proposed learning method is implemented in a long term evolution-advanced network and evaluated via the OPNET-based simulations. The algorithm shows relatively fast convergence and near-optimal performance after a small number of iterations.
Special Issue on Design and Development: Project Management Under Risk: Using the Real Options Approach to Evaluate Flexibility in R...D

Managerial flexibility has value in the context of uncertain R&D projects, as management can repeatedly gather information about uncertain project and market characteristics and, based on this information, change its course of action. This value is now well accepted and referred to as "real option value. " We introduce, in addition to the familiar real option of abandonment, the option of corrective action that management can take during the project. The intuition from options pricing theory is that higher uncertainty in project payoffs increases the real option value of managerial decision flexibility. However, R&D managers face uncertainty not only in payoffs, but also from many other sources. We identify five example types of R&D uncertainty, in market payoffs, project budgets, product performance, market requirements, and project schedules. How do they influence the value from managerial flexibility? We find that if uncertainty is resolved or costs/revenues occurafter all decisions have been made, more variability may "smear out" contingencies and thus reduce the value of flexibility. In addition, variability may reduce the probability of flexibility ever being exercised, which also reduces its value. This result runs counter to established option pricing theory intuition and contributes to a better risk management in R&D projects. Our model builds intuition for R&D managers as to when it is and when it is not worthwhile to delay commitments--for example, by postponing a design freeze, thus maintaining flexibility in R&D projects.
DISCOVERY OF TeV GAMMA-RAY EMISSION FROM TYCHO’S SUPERNOVA REMNANT

We report the discovery of TeV gamma-ray emission from the Type Ia supernova remnant (SNR) G120.1+1.4, known as Tycho's SNR. Observations performed in the period 2008–2010 with the VERITAS ground-based gamma-ray observatory reveal weak emission coming from the direction of the remnant, compatible with a point source located at 00h25m27. ˢ0, + 64°10′50″ (J2000). The TeV photon spectrum measured by VERITAS can be described with a power law dN/dE = C(E/3.42 TeV)−Γ with Γ = 1.95 ± 0.51stat ± 0.30sys and C = (1.55 ± 0.43stat ± 0.47sys) × 10−14 cm−2 s−1 TeV−1. The integral flux above 1 TeV corresponds to ∼0.9% of the steady Crab Nebula emission above the same energy, making it one of the weakest sources yet detected in TeV gamma rays. We present both leptonic and hadronic models that can describe the data. The lowest magnetic field allowed in these models is ∼80 μG, which may be interpreted as evidence for magnetic field amplification.
A nationwide survey of excessive daytime sleepiness in Parkinson's disease in France

To determine the prevalence of excessive daytime sleepiness (EDS) and that of dozing and sudden onset of sleep episodes (SOS) while driving in ambulatory patients with Parkinson's disease (PD) in France, a national sample of private and public neurologists was asked to recruit the first 10 consecutive nondemented PD patients. Each patient completed a questionnaire including the Epworth Sleepiness Scale (ESS) and the likelihood of dozing off and experiencing SOS episodes behind the wheel. Clinical and demographic data were collected. One thousand six hundred and twenty‐five patients with PD were included in the survey. Twenty‐nine percent of the patients suffered from EDS (ESS score ≥10) but only 0.8% declared a high chance of dozing while driving and 0.5% reported totally unpredictable SOS episodes while driving. Risk factors for EDS were male gender, reduced activity of daily living, and a high daily levodopa equivalent dosage. Risk factors for SOS episodes while driving were an ESS score ≥10, male gender, and low Hoehn and Yahr staging. EDS is common in ambulatory patients with PD and is a major risk factor for dozing and for SOS episodes behind the wheel in patients who drive. © 2007 Movement Disorder Society