Miracle-dz/UniFAR-FTUs huggingface dataset:
DEALING WITH LOSS: A HOSPITAL INSERVICE TRAINING PROGRAM

This study addressed the problem of inadequate attention to the emotional aspect of nursing care. The literature attributes this problem both to nurses1 avoidance of dying patients and to their poor communication skills. Based on review of the deatwdying literature including previous studies conducted to educate nurses regarding death/dying and training in communication skills, an inservice training program was developed for nurses. It sought to promote increased awareness of and sensitivity to patients1 emotional distress when experiencing loss and to provide the nurses with communication skills to cope more effectively. The inservice training program was based on a phenomenological-fulfillment model and used an integrative approach recommended by Carkhuff with didactic, experiential and modeling components. The program, involving ten contact hours over a five-week period, was given to ten nurses and one occupational therapist from medical wards in an acute-care hospital. In the quasi-experimental design used to evaluate the inservice training program, two null hypotheses were tested. One sought to determine attitudinal changes using a Death Attitude Questionnaire. The second examined written and audio-taped responses of subjects in a helper's role. Two independent, trained raters evaluated the responses according to Carkhuff's Index of Communication. A t-test was used to compare the preand post-training scores and the questionnaire items were correlated with the independent variables. A third hypothesis investigated the post-training changes observed in nursing care on the ward. Analysis of descriptive data included preand postprogram samplings of nurses' charting and handovers, a post-program interview of the charge nurse, and a case study of one participant which involved preand post-program shadowing and interviews. Results of the study showed no significant attitudinal change as measured by the Death Attitude Questionnaire. Significant improvements occurred on the measures for written and verbal responses of the participants indicating an increased ability to communicate empathically. Data from the work setting showed mixed results. Some
Sub-chronic toxicity study of a novel herbal-based formulation (Semelil) on dogs

Semelil (ANGIPARS™), a novel herbal-based compound containing extract of Melilotus officinalis, was formulated for treatment of chronic wounds, especially diabetic foot ulcer. The purpose of this study was to investigate safety and toxicity effects of intramuscular administration of Semelil in dogs. Preliminary one-month study with Semelil was performed on 8 male and female dogs divided into 2 groups, test and control, four animals each. Semelil was administered intramuscularlyat a dose of 0.07 ml/kg body wt. once a day to the animals of the test group, while the control group received sterile saline. During experiments, general state of the animals including the dynamics of body weight changes, appetite, motor activity and behavior, hair condition, ECG parameters, rectal temperature of animals and data of hematological and biochemical tests were monitored for signs of toxicity and side-effects. Finally, morphology and histology analyses were performed using standard methods. No adverse health or toxicity effects were observed through the course of the study. No damaging consequences of Semelil injections on the functional state of main organs of the experimental animals were found. This observation gave a good evidence of a favorable safety profile compatible with potential therapeutic use of Semelil.
Effectiveness of Tai Chi Practice for Non-Specific Chronic Low Back Pain on Retired Athletes: A Randomized Controlled Study

Objective To determine whether tai chi practice is superior to other means of sports rehabilitation to relieve non-specific chronic low back pain [LBP] in a younger population. Methods We randomized 320 retired athletes [aged 37.6 ± 5.4 years, 60.0 percent men] with chronic LBP [visual analog scale ≥40 mm] into treatment [tai chi practice] and control groups. At the beginning, middle, and end of a six-month intervention, patients from both treatment and control groups completed questionnaires assessing the intensity of LBP, and a systematic physical examination was arranged to evaluate participants' health condition. The results were analyzed by one way analysis of variance using statistical software SPSS 17.0. Differences were considered significant if P < 0.05. Results After three and six months, no statistically significant difference in the intensity of LBP was demonstrated between the tai chi and swimming groups; significant differences were demonstrated among the tai chi and backward walking, jogging, and no exercise groups. Conclusions Tai chi has better efficacy than certain other sports on the treatment of non-specific chronic LBP.
The Importance of Relationship: Elders and Their Paid Family Caregivers in the Arkansas Cash and Counseling Qualitative Study

This article examines the preference of elder consumers for family caregiving, family caregivers' willingness to work for them, and what quality of care means to these elders and their families. It draws on 26 interviews with elders and their family caregivers who participated in Arkansas's Cash and Counseling Program, as part of a consumer-directed national research project. Elders chose family members as caregivers to control the type and scheduling of the care they received. Both elders and family caregivers valued care that took place in the context of a reciprocal relationship. Policy implications include the suitability of consumer direction for elder consumers, an understanding of the way elders define quality of care, and the experience of family caregivers in a consumer-directed program.
Patient Satisfaction With Warfarin- and Non–Warfarin-Containing Thromboprophylaxis Regimens for Atrial Fibrillation

Objective To compare patient-reported limitations, concerns, and burdens in those receiving and not receiving warfarin for thromboprophylaxis in atrial fibrillation (AF). Methods We conducted a cross-sectional survey study of patients with AF receiving thromboprophylaxis for stroke prevention. Patients were administered the validated Anti-Clot Treatment Scale (ACTS). Mean scores of patients receiving and not receiving warfarin were compared for each ACTS item, and for the Burden and Benefit subscales. Results From July 2010 to August 2011, 80 patients with AF were administered the survey, with 65 patients receiving a regimen containing warfarin and 15 patients not receiving a regimen containing warfarin. Six of the 17 individual questions depicting patient- perceived limitations in physical activity due to bleeding, limitations on diet, feelings of inconvenience of occasional aspects of thromboprophylaxis therapy, and frustration, and burden had less favorable scores in the warfarin-managed patients compared with the patients not receiving warfarin (P < 0.05 for all). Mean ACTS Burden scores were more favorable in the no-warfarin group (44.5 ± 6.4) compared with the warfarin group (39.8 ± 8.0; P = 0.003). No difference was seen between the 2 groups on the ACTS Benefits score (11.1 ± 3.4 vs 10.4 ± 3.7; P = 0.38). Conclusion Patients with AF receiving warfarin may have less favorable feelings regarding thromboprophylaxis versus those receiving non-warfarin thromboprophylaxis. Patients report having more limitations and having greater feelings of burden on warfarin.
Correlation of thrombocytopenia in urban childern with malaria

Background: Malaria, is endemic in Surat, (an industrious city of Gujarat), which is categorised under High risk zone. Malaria affects all blood components and is a true haematological disease. Thrombocytopenia and anaemia are the most frequently malaria associated haematological complications of malaria. Aims & Objective: To study the occurrence, severity and correlation of Thrombocytopenia in urban children with malaria. Materials and Methods: A retrospective study was conducted at Surat Municipal Institute Of Medical Education and Research (SMIMER) , Surat Gujarat . The Data of all smear positive and Rapid Diagnostic Test positive malaria cases of age between 1 and 17 year admitted in the Deptt. Of Pediatrics were collected. These patients were further assessed for thrombocytopenia, its severity, its relation with type of malaria and age. Results: Thrombocytopenia was observed in 233 (74%) cases of Malaria of which P. vivax was in 103 (44%) cases, P. falciparum in 130(56%) cases. Severe thrombocytopenia was observed in 22% and 29% cases of Pv and Pf malaria respectively. Sensitivity of thrombocytopenia in Pv and Pf was 71.53% and 76.92% whereas specificity was 66.67 for both respectively. Sensitivity of thrombocytopenia in Pv increased as the platelet count decreased. Conclusion: Thrombocytopenia is a frequent overall manifestation of both falciparum and Vivax malaria Severe Thrombocytopenia should alert one to consider a possibility of malaria in children.
Sustained Endothelial Expression of HoxA5 In Vivo Impairs Pathological Angiogenesis And Tumor Progression

HoxA5 is expressed in quiescent endothelial cells (EC), but absent in activated angiogenic EC. To examine the efficacy of targeting HoxA5 therapeutically to quell pathologic or tumor angiogenesis, we generated an inducible, transgenic mouse model of sustained HoxA5 expression in ECs. During pathologic angiogenesis, sustained HoxA5 regulates expression several angiogenic effector molecules, notably increased expression of TSP-2 and reduced expression of VEGF, thus leading to inhibition of pathological angiogenesis in tissues. To evaluate if this impressive reduction of vascularization could also impact tumor angiogenesis, HoxA5 mice were bred with a mouse model of de novo squamous carcinogenesis, e.g., K14-HPV16 mice. Activation of EC-HoxA5 significantly reduced infiltration by mast cells into neoplastic skin, an early hallmark of progression to dysplasia, reduced angiogenic vasculature, and blunted characteristics of tumor progression. To evaluate HoxA5 as a therapeutic, topical application of a HoxA5 transgene onto early neoplastic skin of K14-HPV16 mice similarly resulted in a significant impairment of angiogenic vasculature and progression to dysplasia to a similar extent as observed with genetic delivery of HoxA5. Together these data indicate that HoxA5 represents a novel molecule for restricting pathological and tumorigenic angiogenesis.
HLA-G and HLA-E Gene polymorphisms in idiopathic recurrent spontaneous abortion women in Gaza strip-Palestine

Human leukocyte antigens (HLA)-G and HLA-E are non-classical HLA class I antigens expressed on extravillous cytotrophoblast that invades decidua in the uterus during pregnancy and are postulated to help in maternal immunotolerance of the fetus. Published results on the relation between HLA-G and HLA-E polymorphisms and unexplained recurrent spontaneous abortion (RSA) are, however, controversial. This study was initiated in order to investigate whether HLA-G ( G*0103, G*0104 and G0105N ) and HLA-E ( E*0101 and E*0103 ) polymorphisms are associated with risk of RSA in Palestinian women. Forty women with ≥2 first trimester unexplained RSAs and 40 age-matched fertile women were genotyped for HLA-G and HLA-E polymorphisms by PCR-RFLP technique. The results revealed the absence of HLA-G*0103 in the study population. No significant difference was observed between the RSA and the fertile groups in terms of the frequency of HLA-G*0104, HLA-G0105N, HLA-E* 0101, or HLA-E*0103 alleles. Interestingly, HLA-G*0105N/0104 genotype was present in the RSA group only and was encountered in 4 patients. The other genotypes showed comparable frequencies in both groups. The presented data suggest that the investigated HLA-G and HLA-E alleles do not predispose to RSA in the study population. Meanwhile, the HLA-G*0105N/0104 genotype may contribute to RSA through linkage disequilibrium with other genetic elements. Larger sample size and further studies are needed in order to confirm this observation.
Effects of wear time recording on the patient's compliance.

OBJECTIVE To assess the effect of wear-time recording on subjective and objective wear time. MATERIALS AND METHODS This study retrospectively examined a group of 18 patients and a control group of 14 patients at four appointments over 168 days. The patients were treated with removable appliances with embedded TheraMon-microsensors to be worn for 15 hours per day. The study group was not told about the microsensor until the first appointment after fitting of the appliance. At each appointment patients were asked about their subjective wear time and afterward were told about the objective wear time. The existence of the microsensor was revealed to the control group when the appliance was fitted. Objective wear time was also announced at every appointment. RESULTS Mean wear times did not significantly differ between groups at any appointment or regarding overall wear time. Highly significant differences between subjective and objective wear time were found when patients did not know that their wear time had been monitored. CONCLUSION Mean wear times assessed in this study concur with data of previous studies. Patients tend to overestimate their wear times but become more realistic once they know wear time is being monitored. Objective measurement of wear time allows a more realistic view of compliance by patient and orthodontist. Knowing that wear time is recorded does not necessarily increase the amount of time removable appliances are worn by the patient.
Preoperative dipyridamole thallium imaging and ambulatory electrocardiographic monitoring as a predictor of perioperative cardiac events and long-term outcome.

BackgroundDipyridamole thallium imaging (DTI) and ambulatory electrocardiography (AEGC) have been advocated as means to stratify risk before vascular surgery. The purpose of this study was to compare the predictive value of both tests in noncardiac surgery patients for perioperative cardiac morbidit
Dentofacial effects of two facemask therapies for maxillary protraction.

OBJECTIVE To compare the dentofacial effects of maxillary protraction with two facemask therapies in growing Class III patients: facemask in association with miniscrew implants (MSI/FM) and facemask with rapid maxillary expanders (RME/FM). MATERIALS AND METHODS Forty-three Chinese patients with Class III malocclusion and maxillary deficiency were randomly assigned to a MSI/FM sample of 20 patients and a RME/FM sample of 23 subjects. The changes in dentofacial cephalometric variables from the beginning (T1) to the end of treatment (T2) were compared with t-test for paired samples in both groups and for independent samples between the two groups. RESULTS No significant cephalometric differences were observed between the two groups in active treatment effects except for maxillary dental variables. However, significant favorable changes in both maxillary and mandibular skeletal components were noted in two groups after treatment. Sagittal measurements showed the maxilla was advanced, mandibular projection was reduced, and the relative sagittal intermaxillary discrepancy improved. Patients experienced additional unfavorable outcomes of clockwise rotation of the mandible as well as retroclination of the lower incisors. The soft tissue profile was improved remarkably in both groups. Proclination of the maxillary incisors and mesialization of the maxillary dentition were significantly different between the two groups. The increases in U1-SN, U1-VR, and U6-VR were 6.41°, 2.78 mm, and 1.24 mm less in the MSI/FM group than in the RME/FM group, respectively. CONCLUSIONS Compared with the RME/FM therapy, the MSI/FM protocol using a smaller magnitude of protraction force improves skeletal relationships and soft tissue profile and reduces the undesired dentoalveolar effects.
Transvaginal colour Doppler ultrasound in predicting response to chemoradiation in patients with carcinoma of the cervix

Abstract Background: The objective of the study was to evaluate the potential role of transvaginal colour Doppler ultrasound (TVCDUS) in predicting response to chemoradiotherapy in patients with locally advanced cervical cancer. Method: TVCDUS was used in 56 patients with histologically proven cervical carcinoma (stage IIA–IIIB) before the start of chemoradiation, and after one and three months of therapy. Resistive index (RI) and pulsatality index (PI) were calculated using TVCDUS. Tumour response to chemotherapy was determined. Complete response was when no residual tumour was found, partial response if the tumour volume decreased by more than 50%, and no response when there was no appreciable change in the size of tumour, or the tumour volume decreased to less than 50% of the original volume. Results: A statistically significant increase in RI and PI was demonstrated with TVCDUS following treatment in patients who had a complete and partial response to chemoradiation, compared to those who had no response. Conclusion: TVCDUS is useful in predicting clinical response to concurrent chemoradiation in patients with locally advanced cervical cancer. Thus, it is recommended during the pretreatment evaluation and follow-up.
Orthodontically induced external apical root resorption in patients treated with fixed appliances vs removable aligners.

OBJECTIVE To determine whether orthodontic treatment with removable aligners vs fixed orthodontic appliances is associated with a different frequency of orthodontically induced external apical root resorption (OIEARR) when genetic, radiographic, and clinical factors are accounted for. MATERIALS AND METHODS Three hundred seventy-two orthodontic patients treated with removable aligners (Invisalign) or fixed appliances were genetically screened for interleukin 1B gene (IL1B) (rs1143634), interleukin 1 receptor antagonist gene (IL1RN) (rs419598), and osteopontin gene (SPP1) (rs9138/rs11730582). Twelve clinical variables, potentially associated with OIEARR, were also considered. Subjects were divided according to the presence of radiographically determined OIEARR (>2 mm). The association between OIEARR and appliance type, and radiographic, clinical and genetic factors, was assessed using backward stepwise conditional logistic regression. Odds ratios (ORs) and 95% confidence intervals (CIs) were reported. RESULTS Reliability of the methods was adequate. Clinical case complexity (American Board of Orthodontics [ABO] Discrepancy Index) (OR: 1.032; 95% CI: 1.005-1.061; P = .021) and extent of incisor apical displacement in the sagittal plane (OR: 1.478; 95% CI: 1.285-1.699; P = .001) were associated with an increased OIEARR risk. After adjusting for associations between clinical/radiographic/genetic factors, there were no statistically significant differences with respect to OIEARR or type of orthodontic appliance used, whether removable aligners or fixed appliances (OR: 1.662; 95% CI: 0.945-2.924; P = .078). Only subjects homozygous for the T allele of IL1RN (rs419598) were more prone to OIEARR during orthodontic treatment (OR: 3.121; CI: 1.93-5.03; P < .001). CONCLUSIONS A similar OIEARR predisposition was identified using either removable aligners (Invisalign) or fixed appliances.
ASPECTOS PSICOSSOCIAIS E QUALIDADE DE VIDA DA DEGENERESCÊNCIA MACULAR RELACIONADA COM A IDADE

Age-related macular degeneration is a major public health problem, which has significant deleterious consequences, given that it causes decreased visual acuity and loss of central vision. This disease is becoming increasingly common among people over 50 years old. Age-related macular degeneration has serious economic consequences, but it is also associated with a significant psychosocial impact and with an important decrement in quality of life of the patient and his/her family. In the present paper we intend to proceed to a literature review related to psychosocial variables implied in diagnostic and treatment of age-related macular degeneration, patients' quality of life, independence and rehabilitation.
Effectiveness of the transpalatal arch in controlling orthodontic anchorage in maxillary premolar extraction cases: A systematic review and meta-analysis.

OBJECTIVE To evaluate the effectiveness of the transpalatal arch (TPA) as an anchorage device in preventing maxillary molar mesialization during retraction of the anterior teeth after premolar extraction. MATERIALS AND METHODS This systematic review intended to include patients indicated for upper premolar bilateral extraction and subsequent retraction of anterior teeth, considering the use of TPA as an anchorage tool in one of the treatment groups. The search was systematically performed, up to April 2015, in the following electronic databases: Medline, Embase, and all evidence-based medicine reviews via OVID, Cochrane Library, Scopus, PubMed, and Web of Science. Risk of bias assessment was performed using Cochrane's Risk of Bias Tool for randomized clinical trials (RCTs) and Methodological Index for Nonrandomized Studies (MINORS) for non-RCTs. RESULTS Fourteen articles were finally included. Nine RCTs and five non-RCTs presented moderate to high risk of bias. Only one study investigated the use of TPA in comparison with no anchorage, failing to show significant differences regarding molar anchorage loss. A meta-analysis showed a significant increase in anchorage control when temporary anchorage devices were compared with TPA (mean difference [MD] 2.09 [95% confidence interval {CI} 1.80 to 2.38], seven trials), TPA + headgear (MD 1.71 [95% CI 0.81 to 2.6], four trials), and TPA + utility arch (MD 0.63 [95% CI 0.12 to 1.15], 3 trials). CONCLUSION Based on mostly moderate risk of bias and with some certainty level, TPA alone should not be recommended to provide maximum anchorage during retraction of anterior teeth in extraction cases.
Survey of Interprofessional Collaboration Learning Needs and Training Interest in Health Professionals, Teachers, and Students: An Exploratory Study

Abstract Background: Researchers and trainers from many professions and settings have emphasized the importance of explicit training in interprofessional collaboration (IPC), but interest in and best practice for training for IPC remains unknown. Methods and Findings: A 33-item Internet-based survey was completed by 486 practicing professionals and students from the sectors of health and education. The survey assessed experiences and knowledge of IPC as well as interest in and barriers to further training in IPC. Overall, there was agreement among respondents regarding the importance of IPC. Satisfaction with IPC was associated with higher self-ratings of knowledge and skills related to IPC. Interest in further IPC training was high, especially for one- or two-day workshops or web-based modules. Qualitative analysis of responses to an open-ended question about IPC skills and knowledge revealed seven networks of common themes that can serve as a framework for training and theory development. Conclusions: IPC training should provide knowledge about IPC models and research, leadership styles, team stages, and conflict management, while also ensuring that training applies to the workplace or practicum placement. Efforts should be made to promote awareness of the need for training in areas where trainees already feel competent.