Miracle-dz/UniFAR-FTUs huggingface dataset:
The Impact of Conservation Information on Average Abnormal Return: Time Series Analysis

The aims of this research are to examine the impact of conservation-based information to average abnormal return of firms. The data which used in this research are all of the news regarding corporate action especially conservation-based information that gathered from Bisnis Indonesia from July 2016 through August 2017. All of the firm which also listed in Sri Kehati Index. The order of the examination within this research are (1) stationery test (2) ARCH or GARCH test (3) Dummy test (Least Square Dummy Variable) and (4) Hypothesis test). The results show that the change in AAR is not influenced by conservation publication made by Bisnis Indonesia. It means that the average AAR difference occurs only in the sample yet the result cannot be generalized in capital market in Indonesia.
Chromosomal translocation‐negative cellular extraskeletal myxoid chondrosarcoma in an adolescent female

Extraskeletal myxoid chondrosarcoma (EMC) is a relatively uncommon soft tissue sarcoma that typically presents in adults of middle age and affects the proximal thigh and limb girdles. Initially believed to be a low‐grade malignancy, long‐term patient follow‐up has shown a high incidence of local recurrence and metastatic spread. EMC is uniformly resistant to chemotherapy and radiation therapy. These tumors characteristically display fibrous septae with large aggregates of mucin populated by clusters and strands of oval cells exhibiting minimal mitotic activity. A more aggressive cellular subtype has also been defined and exhibits basaloid cells showing the immunohistochemical staining features of neuroendocrine differentiation calling into question their proposed cartilaginous lineage. Most, although not all, examples of EMC possess a unique balanced chromosomal translocation [t(9;22)(q22;q12)] between the EWSR1 and NR4A3 (previously termed TEC) genes. Pediatric and adolescent cases of EMC are rare, as only 15 have been reported and appear to follow a more aggressive clinical course. Reported herein is a case of an EMC arising in the thigh of a 15‐year‐old female and the first to undergo evaluation of chromosomal translocation.
High resolution analysis of HIV‐1 quasispecies in the brain

Objective: To characterize HIV‐1 quasispecies at high resolution to determine the in vivo sequence heterogeneity of virus infecting the brain. Methods: A 1 kilobase region of the envelope gene, which includes the five hypervariable regions, was amplified by polymerase chain reaction (PCR) using DNA obtained from brain tissue of an HIV‐1‐infected patient. PCR products were cloned and 50 clones sequenced. Results: Thirty‐nine unique nucleotide sequences producing 35 protein variants were found. A consensus sequence was identified along with three distinct subtypes, each present at a level of 12%. The sequence variation from the concensus was 0.1‐2.1% at the nucleotide level with hypermutation and recombination responsible for the highest diversity. Sequence heterogeneity resulted in both the creation and the elimination of N‐linked glycosylation sites. Only nine clones differed from the consensus sequence in the V3 loop. No inactivating mutations were found. Conclusions: HIV‐1 proviruses found in the brain generally demonstrate a low level of genetic variability in env. However, genomes that vary considerably from the predominant species can be present at significant levels. This observation may be of importance for understanding viral pathogenesis in the central nervous system. AIDS 1995, 9:345‐349
Possible association between thyroid autoimmunity and Menière's disease

Various aetiopathological mechanisms have been postulated to be at the root of Menière's disease (MD), and some data suggest that there may be also an underlying autoimmune factor. In fact, Menière patients manifest certain characteristics that are typical of autoimmune involvement association of particular human leucocyte antigen haplotypes, the presence of antibodies against internal ear antigens. In this study, we evaluated the association between thyroid autoimmunity and MD in a non‐selected group of patients. We recruited 50 consecutive MD patients and two groups as controls: group A, 82 healthy volunteers; and group B, 50 subjects suffering from acute unilateral peripheral vestibulopathy. All subjects were submitted to instrumental assessment of cochlear–vestibular function and analysis of thyroid‐stimulating hormone (TSH), free triiodothyronine, free thyroxine, anti‐TSH receptor antibody (TR‐Ab), anti‐thyroperoxidase antibody (TPO‐Ab) and anti‐thyroglobulin antibody (Tg‐Ab) in the blood. The prevalence of autoimmune thyroiditis in group B [6/50 (12%); 66·7% TPO‐Ab and 33·3% Tg‐Ab] was superimposable with the healthy controls [6/82 (7%); 66·7% TPO‐Ab and 33·3% Tg‐Ab]. In contrast, 38% of the MD patients (P = 0·0001 versus group A and group B) had significant autoantibody levels (68·4% TPO‐Ab; 15·8% TPO‐Ab + TR‐Ab; 10·5% Tg‐Ab; 5·2% TPO‐Ab + Tg‐Ab). Furthermore, 14% of the MD patients were hyperthyroid under l‐thyroxine therapy, while no dysfunction was seen in the control groups. Overall, our data demonstrate a significant association between MD and thyroid autoimmunity, which suggests that an autoimmune factor is involved in the aetiopathogenesis of this disease. These findings suggest that it should be useful to submit MD patients to multi‐disciplinary clinical investigation.
Aspects of dysphoria and symptoms of schizophrenia

Background. In the past it has been postulated that dysphoric emotions may be related to positive and/or negative symptoms in schizophrenia. The results of several recent studies have suggested that composite dysphoria indices are more strongly related to positive than negative symptoms. In the current study we use part correlation techniques to examine the possible unique contributions of two aspects of dysphoria – depression and anxiety – to three syndromes of symptoms (reality distortion, disorganization and psychomotor poverty) within schizophrenia. Methods. Data were obtained from 60 patients with a DSM-III-R diagnosis of schizophrenia. Symptoms of schizophrenia were assessed using the SAPS and SANS and dysphoria was assessed using both self-report (BDI and BAI) and observer ratings (HRSD and HARS). Assessment of schizophrenia symptoms and ratings of depression and anxiety were completed by different observers. In addition, drug induced extrapyramidal side effects were rated. Results. Part correlations showed that unique aspects of anxiety (particularly physiological arousal) were correlated with reality distortion while unique aspects of depression (including psychomotor slowing and loss of social interest) were related to psychomotor poverty. At least part of the latter relationship may be due to extrapyramidal side effects of neuroleptic medication. Conclusions. Although there is considerable overlap between anxiety and depression, it appears that the unique arousing or activating aspects of anxiety are related to the experience of reality distortion symptoms in schizophrenia and the unique slowing and withdrawal aspects of depression are particularly related to psychomotor poverty. Possible reasons for these relationships are discussed.
Which common NIRS variable reflects muscle estimated lactate threshold most closely?

Various near-infrared spectroscopy (NIRS) variables have been used to estimate muscle lactate threshold (LT), but no study has determined which common NIRS variable best reflects muscle estimated LT. Establishing the inflection point of 2 regression lines for deoxyhaemoglobin (DeltaHHb(i.p). ), oxyhaemoglobin (DeltaO2Hb(i.p.)), and tissue oxygenation index (TOIi.p.), as well as for blood lactate concentration, we then investigated the relationships between NIRS variables and ventilatory threshold (VT), LT, or maximal tissue hemoglobin index (nTHImax) during incremental cycling exercise. DeltaHHb(i.p.) and TOI(i.p.) could be determined for all 15 subjects, but DeltaO2Hb(i.p.) was determined for only 11 subjects. The mean absolute values for the 2 measurable slopes of the 2 continuous linear regression lines exhibited increased changes in 3 NIRS variables. The workload and VO2 at DeltaO2Hb(i.p.) and nTHImax were greater than those at VT, LT, DeltaHHb(i.p.), and TOI(i.p.). For workload and VO2, DeltaHHb(i.p.) was correlated with VT and LT, whereas DeltaO2Hb(i.p.) was correlated with nTHImax, and TOI(i.p.) with VT and nTHImax. These findings indicate that DeltaO2Hb strongly corresponds with local perfusion, and TOI corresponds with both local perfusion and deoxygenation, but that DeltaHHb can exactly determine deoxygenation changes and reflect O2 metabolic dynamics. The finding of strongest correlations between DeltaHHb and VT or LT indicates that DeltaHHb is the best variable for muscle LT estimation.
Factor Endowments and Farm Structure : Algerian Settler Agriculture During the First Globalization (1870-1914)

The adaptation of crops, agricultural techniques, and farm size to the new environments ushered in by colonialism help identify the sources of long-term development. This paper is a simplified approach to this adaptation process. It analyzes the relative factor endowments (land and labor) based on the timing of settlement to study the regional differences in the adoption of improved agricultural techniques in Constantine at the beginning of the 1900s. During the colonial years, the Algerian farming system diverged into large estates reliant on indigenous wage labor and sharecropping. As fertile land became increasingly scarce, the ability to participate in the grain export market depended on the capability of engaging in new and non-labor saving agricultural techniques. The results demonstrate that innovation in cash-crop production depended on the abundance of indigenous labor but also required a significant capital investment to offset the worse land quality. Thus, access constraints to agricultural advancement help explain the Algerian origins of colonial land inequality and the failure of colonial institutions to create a small-peasant settler economy.
Testosterone treatment enhances thromboxane A2 mimetic induced coronary artery vasoconstriction in guinea pigs

Abstract. Thromboxane A2 (TXA2) has been implicated as an important mediator of cardiovascular diseases. There have been several clinical reports of acute myocardial infarctions occurring in young male athletes abusing anabolic steroids. The effects of treatment of male Guinea pigs with testosterone on the responses to U46619, a TXA2 receptor agonist, in the isolated perfused heart were determined. The maximum pressor responses of the isolated perfused Guinea pig heart to U46619 were significantly (P < 0·05) greater in the Guinea pigs treated with testosterone compared to the controls. These results indicate that testosterone can enhance coronary artery vascular reactivity to TXA2.
Optimization of Passive Envelop Energy Efficient Measures for Office Buildings in Different Climate Regions of China Based on Modified Sensitivity Analysis

With the growing desire for new buildings and better indoor comfort, the amount of energy consumption of office buildings in China is increasing rapidly, which will lead to the great challenge for energy supply and sustainable development. Building passive envelop energy efficient measures (PEEEMs), mainly including exterior wall insulation, roof insulation, different glazing types, and shading system, were widely applied. However, the specific energy efficient performance of PEEEMs was various in different climate conditions that have not been evaluated clearly yet. The priority order of PEEEMs was not recommended in relative standards. The economic benefits cannot be considered synchronously with PEEEMs optimization. This paper modified the sensitivity analysis to fit the building energy efficiency evaluation. By combining the modified method with a simulation tool, the energy efficiency and economic effects of PEEEMs of office buildings in various climate regions can be considered at the same time. Four case buildings in Shenyang, Tianjin, Ningbo, and Shenzhen were proved to reach the energy-saving potentials of 9.44%, 7.75%, 20.87%, and 13.27% respectively, with the payback period of no more than 1.5 years. Finally, the recommended application priority rankings and the recommended ranges of thermal performance properties of PEEEMs in the four typical climate regions were presented.
Transplantation of in vitro‐expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats

Neural progenitor cells, including neural stem cells, are a potential expandable source of graft material for transplantation aimed at repairing the damaged CNS. Here we present the first evidence that in vitro‐expanded fetus‐derived neurosphere cells were able to generate neurons in vivo and improve motor function upon transplantation into an adult rat spinal‐cord‐contusion injury model. As the source of graft material, we used a neural stem cell‐enriched population that was derived from rat embryonic spinal cord (E14.5) and expanded in vitro by neurosphere formation. Nine days after contusion injury, these neurosphere cells were transplanted into adult rat spinal cord at the injury site. Histological analysis 5 weeks after the transplantation showed that mitotic neurogenesis occurred from the transplanted donor progenitor cells within the adult rat spinal cord, a nonneurogenic region; that these donor‐derived neurons extended their processes into the host tissues; and that the neurites formed synaptic structures. Furthermore, analysis of motor behavior using a skilled reaching task indicated that the treated rats showed functional recovery. These results indicate that in vitro‐expanded neurosphere cells derived from the fetal spinal cord are a potential source for transplantable material for treatment of spinal cord injury. © 2002 Wiley‐Liss, Inc.
Where Less is More: Reducing Variable Annuity Fees to Benefit Policyholder and Insurer

In the United States, variable annuities (VAs) are popular long&#8208;term personal investment vehicles. Recently, however, sales have begun to dwindle. In fact, financial advisers have long argued against investing in VAs due to the products&#8217; high fees. VA providers charge these fees&#8212;typically at a constant rate throughout the policy period&#8212;to cover their expenses and the costs of embedded guarantees, and lowering this constant fee rate could make the VA unprofitable. Instead, we propose and analyze a simple change to the fee &#8220;structure&#8221; that would lower fee rates overall (and thus make the product more attractive to investors) without reducing the insurer's profit. The key insight is that this time&#8208;dependent fee rate (with moderate front&#8208;loading) implicitly discourages policy lapses and exchanges, which reduces the providers&#8217; policy acquisition expenses. Taking into account financially optimal lapse (and reentry) decisions, we determine the optimal timing and rate of the fee reduction for a competitive as well as for an innovative VA provider. An important characteristic of this feature is that it can be implemented easily and effectively to both new and existing VA policies.
Acoustic profiles in vocal emotion expression.

Professional actors' portrayals of 14 emotions varying in intensity and valence were presented to judges. The results on decoding replicate earlier findings on the ability of judges to infer vocally expressed emotions with much-better-than-chance accuracy, including consistently found differences in the recognizability of different emotions. A total of 224 portrayals were subjected to digital acoustic analysis to obtain profiles of vocal parameters for different emotions. The data suggest that vocal parameters not only index the degree of intensity typical for different emotions but also differentiate valence or quality aspects. The data are also used to test theoretical predictions on vocal patterning based on the component process model of emotion (K.R. Scherer, 1986). Although most hypotheses are supported, some need to be revised on the basis of the empirical evidence. Discriminant analysis and jackknifing show remarkably high hit rates and patterns of confusion that closely mirror those found for listener-judges.
Limits to the host range of the highly polyphagous tephritid fruit fly Anastrepha ludens in its natural habitat

Abstract Anastepha ludens (Diptera: Tephritidae) is a highly polyphagous fruit fly that is able to develop in a wide range of hosts. Understanding the limits of this pest's host range could provide valuable information for pest management and plant breeding for pest resistance. Previous studies have shown that guavas (Psidium guajava (Myrtaceae) L. ), are not attacked under natural conditions by A. ludens. To understand this phenomenon, guavas were exposed to natural infestation by A. ludens and to other fruit fly species that infest guavas in nature (Anastrepha striata Schiner, Anastepha fraterculus (Wiedemann), Anastepha obliqua (Macquart)). Once the susceptible phenological stage of guavas was determined, fruit infestation levels were compared between A. ludens and A. striata. Choice and non-choice tests were performed under field-cage conditions. Under field conditions, guavas were susceptible to A. striata and A. fraterculus attack all the way from when fruit was undeveloped to when fruit began to ripen. No infestation by A. ludens was recorded under natural conditions. Similar results were obtained when forced exposures were performed, indicating that unripe guavas were preferred by A. striata over ripe fruit, and that infestation rates were higher at early fruit maturity stages. Under forced oviposition conditions, A. ludens larvae were unable to develop in unripe guavas but did so in fully ripe fruit. However, A. ludens fitness parameters were dramatically affected, exhibiting reduced survival and reduced pupal weight compared to conspecifics that developed in a natural host, grapefruit. We confirm that P. guajava should not be treated as a natural host of this pestiferous species, and suggest that both behavioral aspects and the fact that larvae are unable to adequately develop in this fruit, indeed represent clear limits to A. ludens's broad host range.
An outbreak of cryptosporidiosis associated with a swimming pool

SUMMARY In August 1988 an increase was noted in the number of cases of cryptosporidiosis identified by the microbiology laboratory at Doncaster Royal Infirmary. By 31 October, 67 cases had been reported. Preliminary investigations implicated the use of one of two swimming pools at a local sports centre and oocysts were identified in the pool water. Inspection of the pool revealed significant plumbing defects which had allowed ingress of sewage from the main sewer into the circulating pool water. Epidemiological investigation confirmed an association between head immersion and illness. The pools were closed when oocysts were identified in the water and extensive cleaning and repair work was undertaken. The pool water was retested for cryptosporidial oocysts and found to be negative before the pool re-opened.
UvrB Domain 4, an Autoinhibitory Gate for Regulation of DNA Binding and ATPase Activity*

UvrB, a central DNA damage recognition protein in bacterial nucleotide excision repair, has weak affinity for DNA, and its ATPase activity is activated by UvrA and damaged DNA. Regulation of DNA binding and ATP hydrolysis by UvrB is poorly understood. Using atomic force microscopy and biochemical assays, we found that truncation of domain 4 of Bacillus caldotenax UvrB (UvrBΔ4) leads to multiple changes in protein function. Protein dimerization decreases with an ∼8-fold increase of the equilibrium dissociation constant and an increase in DNA binding. Loss of domain 4 causes the DNA binding mode of UvrB to change from dimer to monomer, and affinity increases with the apparent dissociation constants on nondamaged and damaged single-stranded DNA decreasing 22- and 14-fold, respectively. ATPase activity by UvrBΔ4 increases 14- and 9-fold with and without single-stranded DNA, respectively, and UvrBΔ4 supports UvrA-independent damage-specific incision by Cho on a bubble DNA substrate. We propose that other than its previously discovered role in regulating protein-protein interactions, domain 4 is an autoinhibitory domain regulating the DNA binding and ATPase activities of UvrB.
Proposal for a new ALICE CPV-HMPID front-end electronics topology

This paper presents the proposal of a new front-end readout electronics (RO) architecture for the ALICE Charged-particle Veto detector (CPV) located in PHOton Spectrometer (PHOS), and for the High Momentum particle IDentification detector (HMPID). With the upgrades in hardware typology and proposed new readout scheme in FPGA design, the RO system shall achieve at least five times the speed of the present front-end readout electronics. Design choices such as using the ALTERA Cyclone V GX FPGA, the topology for parallel readout of Dilogic cards and an upgrade in FPGA design interfaces will enable the RO electronics to reach an approximate interaction rate of 50 kHz. This paper presents the new system hardware as well as the preliminary prototype measurement results. This paper concludes with recommendations for other future planned updates in hardware schema.
HEMIFIELD MEMORY FOR ATTRACTIVENESS

In order to determine whether or not facial attractiveness plays a role in hemispheric facial memory, 35 right-handed participants first assigned attractiveness ratings to faces and then performed a recognition test on those faces in the left visual half-field (LVF) and right visual half-field (RVF). We found significant interactions between the experimental factors and visual half-field. There were significant differences in the extreme ends of the rating scale, that is, the very unattractive versus the very attractive faces: Female participants remembered very attractive faces of both women and men, with memory being superior in the RVF than in the LVF. In contrast, the male participants remembered very unattractive faces of both women and men; RVF memory was better than the LVF for women faces while for men faces memory was superior in the LVF. The interactions with visual half-field suggest that hemispheric biases in remembering faces are influenced by degree of attractiveness.
The Effect of Work Ethic on Employees' Individual Innovation Behavior

The present study examines the previously untested effect of work ethic on individual innovation behavior. These entrenched personal values that may remain unaffected by organizational constitution are suggested to shape a person's inclination to engage in innovative action. Deploying partial least squares (PLS) structural equation modeling (SEM), we show that being self-reliant and time-efficient positively influences employees' innovation behavior, while an attitude toward hard work and leisure has a negative impact. Moreover, self-reliance, leisure orientation, and centrality of work are positively moderated by fair salary, a specific form of relational reward that previously has been identified as an antecedent of motivation. The work at hand thus contributes to extant research by enhancing knowledge about the antecedents of innovative behavior, showing that inherent work-related values matter. As such, the study demonstrates the importance of considering the linkage of personal differences and motivational factors when examining the complex processes of individual innovation behavior.