Miracle-dz/UniFAR-FTUs huggingface dataset:
Rosacea‐Like Demodicidosis in an Immunocompromised Child

Abstract: Demodex folliculorum is a saprophytic mite of the human pilosebaceous unit. It is rarely found in children. It has been implicated in the development of follicular pityriasis, rosacea‐like demodicidosis, pustular folliculitis, blepharitis, and granulomatous rosacea. We describe a 4‐year‐old boy who developed asymptomatic facial lesions that histologically corresponded to demodicidosis. He was in clinical remission of acute lymphoblastic leukemia and currently receiving maintenance chemotherapy. Exanthems related to D. folliculorum are rare in children. Most cases occur in immunocompromised patients and the clinical and histologic findings are diverse. A differential diagnosis should be established with rosacea and perioral dermatitis. The role of Demodex in the pathogenesis of these disorders is controversial. Immunosuppression might increase the number of mites, favoring an inflammatory reaction, or there could exist an impaired cutaneous immunologic response to the parasites.
Mammogram Classification Using Association Rule Mining

- Breast cancer is the primary and the most common disease found among women. It is responsible for rapid growth in mortality rate among all types of cancers in women. Today, mammography the most powerful screening technique is used for early detection of cancer which increases the chance of successful treatment. Screening with mammography can show changes in the breast up to 2-3years before a physician can feel them. But it is not a perfect solution due to abnormalities that are not observable, abnormalities that are misinterpreted and technical problems in the imaging process. Therefore there is a significant need of computer aided detection system which can produce intended results and assist medical staff for accurate diagnosis at an early stage of breast cancer. Much research has been done in the field of mammogram classification during last two decades. With all this effort, there is still no widely used method for mammogram classification because this domain requires high accuracy. With this objective, an attempt is made to build mammogram classification system using association rule mining. In this paper an efficient association rule mining method is proposed to mine hidden relationships and trends in the digital mammograms for accurate classification. Experiments are carried out using MIAS Image Database. The performance of the proposed method is compared with the standard Apriori algorithm. It is found that the proposed method performs better due to reduction in multiple times scanning of database which results in less computation time. Also the mammogram classification system using this method can provide better accuracy up to 90% as compared with the other associative classification techniques. Thus this paper illustrates the use and effectiveness of association rule mining for mammogram classification.
Formation of an ordered ice layer on a thin silica film

Adsorption of water on a thin silica film grown on a Mo(112) single crystal was studied by temperature-programmed desorption, infrared reflection absorption spectroscopy, and photoelectron spectroscopy using synchrotron radiation. Water does not dissociate on the defect-free oxygen-terminated silica surface. In contrast to adsorption at 100 K, where water follows a zero-order desorption kinetics, water adsorbed at 140 K exhibits a pseudo-first-order kinetics and induces a strong blue shift of the silica phonon. Even larger spectral changes were observed for D2O adsorption. The results were rationalized in terms of the formation of an amorphous solid water film at 100 K and a crystalline ice monolayer film at 140−150 K. This film is well-ordered as revealed by low-energy electron diffraction showing a c(2 × 2) superstructure with respect to the silica substrate.
A comparison of two treatments of agitated behavior in nursing home residents with dementia: simulated family presence and preferred music.

OBJECTIVE The objective of this study was to compare the effectiveness of two individualized psychosocial treatments in reducing the frequency of physically and verbally agitated behaviors in nursing home residents whose dementia was complicated by marked behavioral disturbance. METHODS Thirty nursing home residents with frequent, severe behavioral disturbances were observed by research staff before, during, and after multiple, randomized, single-blind exposures to 15-minute audiotapes of simulated family presence (a conversation prepared by a family member about positive experiences from the past), music preferred by the resident in earlier life, and a placebo condition of a reading from a horticultural text. Selected (usually multiple) physical and verbal behaviors were counted as present or absent at regular intervals. All three treatment conditions were compared with usual care. RESULTS Simulated presence and preferred music both proved effective in reducing counts of physically agitated behaviors. Simulated presence, but not music, resulted in significantly reduced counts of verbally agitated behaviors. The placebo tape proved more effective than expected. Participants' responses to simulated presence and music varied widely. Behavior counts fell by one-half or more in many cases. Other residents became more agitated. CONCLUSION Participants' better-than-expected responses to the placebo tape suggest that even the simplest technology can improve the lives of confused, disturbed nursing home residents. Of the two psychosocial treatments, preferred music tapes were easier to make and were clearly helpful in many instances. By contrast, family members often struggled to recall enough happy memories to compile a simulated presence tape. Simulated presence might prove just as effective if relatives speak on topics of their own choosing. Although not all residents were helped by these treatments, adverse effects were mild and shortlived.
High Power Discharge Lamps and Their Photochemical Applications: An Evaluation of Pulsed Radiation

In the past decades, gas discharge lamps have gained widespread use in industrial applications. Due to their unique design properties concerning spectral, electrical and geometrical features, all types of gas discharge lamps can been found in technical applications. Mercury based lamps are the workhorses in many applications upgraded by their relatives, the metal halide versions. The low and medium pressure mercury lamps are usually used as sources of UV radiation. Low pressure mercury lamps are used extensively for disinfection of drinking water, packing material and air. Medium pressure lamps are applied in printing industry to dry inks and cure adhesives, in waste water treatment plants to reduce the total organic compounds (TOC) and as a competing technology to low pressure versions in germicidal applications. Metal halide doped versions of medium and high pressure mercury lamps open the possibility to adjust spectral output to specific requirements.
Dosing issues and depot medication in the maintenance treatment of schizophrenia

Antipsychotic medication has proved to be of enormous value in the long-term treatment of schizophrenia. Maintenance medication has been shown to reduce rates of relapse and rehospitalization substantially and to enable patients to benefit from psychosocial treatments and vocational rehabilitation. At the same time, improving compliance while optimizing the benefits and minimizing the risks associated with long-term drug treatment has been a major challenge. Depot medications are a valuable part of a maintenance strategy for many patients. Considerable data are now available on dose-response relationships with depot drugs, improving our ability to use them judiciously.
New Enhancements for the Exact Solution of the Vehicle Routing Problem with Time Windows

The vehicle routing problem with time windows VRPTW consists of finding least-cost vehicle routes to satisfy the demands of customers that can be visited within specific time windows. We introduce two enhancements for the exact solution of the VRPTW by branch-price-and-cut BPC. First, we develop a sharper form of the limited-memory subset-row inequalities by representing the memory as an arc subset rather than a node subset. Second, from the elementary inequalities introduced by Balas in 1977, we derive a family of inequalities that dominate them. These enhancements are embedded into an exact BPC algorithm that includes state-of-the-art features such as bidirectional labeling, decremental state-space relaxation, completion bounds, variable fixing, and route enumeration. Computational results show that these enhancements are particularly effective for the most difficult instances and that our BPC algorithm can solve all 56 Solomon instances with 100 customers and 51 of 60 Gehring and Homberger instances with 200 customers. The online appendix is available at https://doi.org/10.1287/ijoc.2016. 0744 .
The deterrent effect of the perceived certainty and severity of punishment: A review of the evidence and issues

This paper critically examines the role of the perceived certainty and severity of punishment in deterring criminal/deviant behavior. A thorough review of the perceptual deterrence literature from 1972–1986 is provided which indicates that cross-sectional correlations between perceptions of sanction threats and self-reported criminal/deviant behavior are moderately negative for diverse offenses, consistent with the deterrence doctrine. It is noted that rather than expressing the deterrent effect, these correlations probably indicate the effect of prior behavior on currently held perceptions—the experiential effect. In addition, since in many instances the reported correlations express simple bivariate relationships, the association may be spurious rather than causal. When researchers employing panel designs have estimated the deterrent relationship with variables in their correct temporal ordering and with more fully specified causal models, the moderate inverse effect for both perceived certainty and sev.
Novel Human Transitional B Cell Populations Revealed by B Cell Depletion Therapy1

Transitional cells represent a crucial step in the differentiation and selection of the mature B cell compartment. Human transitional B cells have previously been variably identified based on the high level of expression of CD10, CD24, and CD38 relative to mature B cell populations and are expanded in the peripheral blood following rituximab-induced B cell-depletion at reconstitution. In this study, we take advantage of the gradual acquisition of the ABCB1 transporter during B cell maturation to delineate refined subsets of transitional B cells, including a late transitional B cell subset with a phenotype intermediate between T2 and mature naive. This late transitional subset appears temporally following the T1 and T2 populations in the peripheral compartment after rituximab-induced B cell reconstitution (and is thus termed T3) and is more abundant in normal peripheral blood than T1 and T2 cells. The identity of this subset as a developmental intermediate between early transitional and mature naive B cells was further supported by its ability to differentiate to naive during in vitro culture. Later transitional B cells, including T2 and T3, are found at comparatively increased frequencies in cord blood and spleen but were relatively rare in bone marrow. Additional studies demonstrate that transitional B cells mature across a developmental continuum with gradual up-regulation of mature markers, concomitant loss of immature markers, and increased responsiveness to BCR cross-linking in terms of proliferation, calcium flux, and survival. The characterization of multiple transitional B cell subpopulations provides important insights into human B cell development.
Development and evaluation of shelf stable retort processed ready-to-drink (RTD) traditional Thari kanchi payasam in flexible retort pouches.

Thari kanchi payasam is an Indian traditional delicacy was prepared as per traditional method. It is a light sweetened hot drink made from milk with very little semolina and seasoned with nuts and raisins, consumed during Ramzan fasting period. The Ready-to-drink packed in four layer retort pouches and processed in a steam-air retort with overriding pressure. Time-temperature data was collected during heat processing using an Ellab data recorder cum F 0 integrator. The heat penetration characteristics were determined. The total process time (TB) was 35 min with a F 0 value of 3.64. The product was evaluated for its shelf stability under ambient (27-30 o C) and elevated (45 o C) conditions for a period of 12 months. On storage, changes in moisture content, total fat, protein, free fatty acid (FFA), and Peroxide value (PV) were determined at every 3 month intervals. Moisture and protein content of the product did not show any significant changes, and the total fat content was found to decrease. FFA was found to increase 1.92 ± 0.01, 2.75 ± 0.01 at ambient and elevated temperature respectively, from an initial value of 0.281 ± 0.001. Microbiological analysis revealed that product was commercially sterile and fit for consumption. The samples were rated excellent by the taste panel and remained in good condition even after storage period
The influence of drugs used in neuroleptanalgesia on cardiovascular and ventilatory function.

SUMMARY The circulatory and ventilatory influences of various combinations of the narcotic analgesics phenoperidine and fentanyl, and the neuroleptics haloperidol and dehydrobenzperidol, were investigated during nitrous oxide anaesthesia in 230 patients. Measurements of cardiac output and other haemodynamic variables in nine patients supported the general findings that the cardiovascular effects of the analgesics were modified by alterations of ventilation, in particular the haemodynamic effects of concurrent hypercapnia. Serious circulatory disturbances were not found following premedication with neuroleptic drugs. Mechanisms of ventilatory depression following the use of the analgesics have been evaluated, and indices of ventilation and arterial oxygenation show that postoperative values after neuroleptanalgesia are comparable to those after other methods of anaesthesia. The rationale of neuroleptanalgesia combined with light general anaesthesia is explored and the pharmacology of the drugs is reviewed.
Buoyant Density Analysis of Staphylococcal Bacteriophage 80 Transducing Particles

Densities of pase, tet, and ol transducing particles were indistinguishable, and about 0.002 g × cm−3 less dense than the plaque-forming units (PFU). The densities of the PFU and nov transducing particles were indistinguishable, the PFU having a density of 1.507 g × cm−3.
Kimya Öğretmen Adaylarının Öz-Yeterlik İnançlarının Bazı Değişkenler Açısından İncelenmesi

Bir bireyin oz-yeterlik inanci, onun algisini, motivasyonunu ve performansini bir cok sekilde etkiler. Insanlarin motivasyon duzeyleri duyussal durumlari ve davranislari; objektif olarak durumun ya da olayin ne oldugundan cok, ayni zamanda bireylerin bir sorunla ya da hos olmayan bir deneyimle karsilastiklarinda, ne kadar caba harcayacaklarini ve ne kadar sure bu sorunla yuz yuze kalabileceklerini de belirlemektedir. Ilk kez Bandura(1) tarafindan vurgulanan “Ozyeterlik Inanci’nin”; sadece sosyallesme surecindeki davranis degisikliklerinde degil, ayni zamanda mevcut disiplinlerdeki ogrenci basarisinda da onemli rolu oldugu, bugun bilinen bir gercektir (2). Calismada; ogretmenlerin mesleklerini tam bir verimle gerceklestirmelerinde, branslariyla ilgili oz-yeterlik inanclarinin buyuk rolu oldugu goz onune alinmistir. Bu amacla; Morgil, Secken ve Yucel (13) tarafindan Hacettepe Universitesi Egitim Fakultesi Kimya bolumune uygulanarak gelistirilen olcek, farkli bir universitenin Egitim Fakultesi Kimya bolumunde okuyan ogretmen adaylarina uygulanmis, uygulama sonuclari, bazi degiskenler goz onunde bulundurularak tartisilmistir. Olcegin gelistirilmesi, uygulanmasi ve bazi degiskenler acisindan degerlendirilmesi SPSS 11 paket programi ile gerceklestirilmistir
A Model of Foreign-Born Transfers: Evidence from Canadian Micro Data

This paper models financial transfers outside the household for both the Canadian-born and foreign-born Canadian populations in a traditional expenditure framework. Using survey data we estimate transfer functions as part of a larger expenditure system and calculate Engel elasticities for remittances by both the Canadian and foreign-born populations. We conclude that transfers outside the household are a normal good for recent Asian immigrants and a luxury good for all other immigrants and Canadians. Immigrant transfers upon arrival are greater than Canadian-born transfers indicating a strong entry effect. Assimilation or convergence to the Canadian-born norm over time is however very slow. We also find evidence of negative foreign-born transfers as sending country households remit to Canadian immigrant households. Finally, all foreign-born groups generally consider remittances to charitable organizations a greater necessity than inter-household transfers.
Screening of Penicillium species for occurrence of lectins and their characterization

Out of 15 Penicillium species screened for lectin activities, P. griseofulvum and P. thomii were found to possess mycelial lectin activity. None of the species displayed extracellular or cell surface‐bound lectin activity. Both species agglutinated rabbit erythrocytes. P. griseofulvum lectin showed specificity to human type O erythrocytes. While P. thomii lectin specifically agglutinated human type A erythrocytes. Highest lectin activities from P. thomii and P. griseofulvum were expressed after 8 and 7 days of growth, respectively. Lectins from both the species displayed a high binding affinity to chondroitin‐6‐sulphate, mucin, asialofetuin, D‐sucrose, and D‐trehalose. Ammonium sulphate at 50% saturation yielded 80% of the total lectin activity. Dialysis and ultrafiltration of the precipitates resulted in 1.79 and 3.46 fold purification of P. griseofulvum and P. thomii lectins, respectively. Both lectins showed pH optima between 7.0–8.0 and were stable near the neutral pH after 2 h. P. thomii lectin exhibited optimal activity at 35–40 °C, and P. griseofulvum lectin at 30–40 °C. P. thomii lectin showed a complete loss of activity above 40 °C, P. griseofulvum lectin was stable at or below 35 °C. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Multiple Object Tracking in People With Williams Syndrome and in Normally Developing Children

Multiple object tracking is hypothesized to utilize visual indexes, which may provide rapid, parallel access to a limited number of visual objects, thereby supporting a variety of spatial tasks. We examined whether faulty indexing might play a role in the severe visuospatial deficits found in Williams syndrome. We asked observers to track from one to four targets in a display of eight identical objects. Objects remained stationary (static condition) or moved randomly and independently (moving condition) for 6 s, after which observers pointed to the objects they thought were targets. People with Williams syndrome were impaired in the moving condition, but not the static condition, compared with mental-age-matched control participants. Normal children who were younger than the mental-age-matched control children did not show the same profile as individuals with Williams syndrome, which suggests that the difference between the tasks in Williams syndrome did not reflect simple developmental immaturity. Error analysis revealed that all groups had “slippery” indexes, falsely identifying target neighbors, and further suggested that people with Williams syndrome deploy fewer indexes than do people without this disorder.
Peroxisome Proliferator-activated Receptor α Controls the Hepatic CYP4A Induction Adaptive Response to Starvation and Diabetes*

The hepatic CYP4A enzymes are important fatty acid and prostaglandin ω-hydroxylases that are highly inducible by fibric acid hypolipidemic agents and other peroxisome proliferators. Induction of the CYP4A enzymes by peroxisome proliferators is mediated through the nuclear peroxisome proliferator-activated receptor α (PPARα). Fatty acids have recently been identified as endogenous ligands of PPARα, and this receptor has been implicated in the regulation of lipid homeostasis. In the present report we characterized the induction of the hepatic CYP4A genes in rats during the altered lipid metabolism associated with starvation and diabetes. The mRNA levels of CYP4A1, CYP4A2, and CYP4A3 were induced 7–17-fold in the livers of fasted animals and 3–8-fold in the livers of diabetic animals. This was accompanied by corresponding changes in CYP4A protein levels and arachidonic and lauric acid ω-hydroxylase activity. Interestingly, feeding animals after the fasting period caused as much as an 80% suppression of CYP4A mRNA levels, whereas CYP4A protein levels and functional activity returned to control values. A second PPARα-responsive gene, acyl-CoA oxidase, was also induced in rat liver by diabetes and fasting. By using PPARα-deficient mice, we unambiguously demonstrated that PPARα is strictly required for hepatic CYP4A induction by starvation and diabetes. Similarly, induction of hepatic thiolase and bifunctional enzyme also required expression of PPARα. This represents the first evidence for the pathophysiologically induced activation of a nuclear receptor.
Variable expression of soluble fms-like tyrosine kinase 1 in patients at high risk for preeclampsia

Objective. To explore angiogenic factor differences in preeclamptic patients according to the absence or presence of underlying vascular disease. Methods. We prospectively compared serum soluble fms-like tyrosine kinase 1 (sFlt1), soluble endoglin, and placental growth factor (PlGF) from 41 normal-risk and 32 high-risk (preexisting conditions) subjects at serial gestational ages. Results. Median sFlt1 was lower at delivery in preeclamptic patients with underlying chronic hypertension and/or chronic proteinuria (5115 pg/ml) compared with normal risk preeclamptic patients (16375 pg/ml). PlGF was consistently low in patients who developed preeclampsia. Conclusions. Effects of sFlt1 may be contextual, varying according to the health or disease state of vascular endothelium.