Miracle-dz/UniFAR-FTUs huggingface dataset:
DEVELOPMENT AND STABILITY INDICATING HPLC METHOD FOR DAPAGLIFLOZIN IN API AND PHARMACEUTICAL DOSAGE FORM

Objective: To develop precise, accurate and reproducible stability assay method by RP-HPLC for estimation of dapagliflozin in API and pharmaceutical dosage form. Methods: The adequate separation was carried using agilent C18 (4.6 ml (millimeter)*150,5 µm (micromiter), mixture of acetonitrile : di-potassium hydrogen phosphate with pH-6.5 adjusted with OPA (40:60 %v/v) as a mobile phase with the flow rate of 1 ml/min (milliliter/minute) and the effluent was monitored at 222 nm (nanometer) using photo diode array detector. The retention time of dapagliflozin API and dapagliflozin tablet were 3.160 min (minute) and 3.067 min (minute) respectively. Results: Linearity for dapagliflozin was found in the range of 50-150µg/ml (microgram/milliliter) (R 2 = 0.99) respectively. The accuracy of the present method was evaluated at 50 %, 100% and 150%. The % recoveries of dapagliflozin API and tablet were found to be in the range of 99.00–99.99 % and 98.50–99.99 % respectively. Precision studies were carried out and the relative standard deviation values were less than two. The method was found to be robust. Conclusion: The proposed method was found to be specific, accurate, precise and robust can be used for estimation of dapagliflozin in API and Pharmaceutical dosage form.
In vivo evaluation of antidiarrhoeal activity of the leaves of Azima tetracantha

The aqueous crude extract of the leaves of Azima tetracantha was studied for its phytochemical constituents and antidiarrhoeal activity using castor oil-induced diarrhoea and castor oil-induced enteropooling in rats. The phytochemical studies of the aqueous extract revealed the presence of alkaloids, flavonoids, tannins and saponins. The extract showed significant (p < 0.001) protection against castor oil-induced diarrhoea and castor oil-induced enteropooling at (100 mg/kg). The presence of some of the phytochemicals in the root extract may be responsible for the observed effects, and also the basis for its use in traditional medicine as antidiarrhoeal drug.
Real-Time Classification Algorithm for Recognition of Machine Operating Modes by Use of Self-Organizing Maps

In this paper a new algorithm for classication and real-time recognition of dierent a-priorily assumed operating modes for construction machines is proposed. This algorithm utilizes the eectiveness of the Self-Organizing Maps (SOM) for creating the so called Separation Models, that are able to distinguish each operating mode separately. After training, these models are used in a real-time procedure, which calculates at each sampling time the minimal Euclidean distances from the current data point to a certain node of each SOM. Then the separation model (represented by a respective SOM) that has the least minimal distance to this data point denes the class of the current operating mode. Simulation results and extensive analysis, based on experimental data from a hydraulic excavator have shown that the proposed algorithm outperforms the standard one-model approach. It is faster in the terms of computation time for training and leads to a higher percentage of true recognitions.
An Empirical Study on the Relationships between TQM Practices and Overall Service Performance: The Case of a Public Service Sector in Malaysia

In recent years, the TQM movement has swept the service sector in Malaysia because the shift towards quality practices is crucial to the survival of service firms. Some studies have proven that TQM practices have significantly positive impact on organizational performances. This study sought to enhance understandings of relationships between TQM practices and the overall service performance of a public service sector in Malaysia. Methods include correlation and multiple regression analyses. The result of the overall multiple linear regression indicates that the model has a good fit. In addition, this paper further investigates correlations of the variables and the overall regression model for the present of multicollinearity and found that its existence is low. The overall result from the multiple linear regression suggests that some of the regression coefficients of the predictor variables (TQM practices) are significant toward explaining the dependent variable (service performance).
The Relationship of Hypnotizability and Empathy: A Replication and Extension Study

A recent research article articulated the Empathic Involvement Theory of hypnotizability (EIT; Wickramasekera II, 2015). The theory holds that individual differences in hypnotizability are correlated with, and in part determined by, the capacity to empathize. I review the theory and the founding empirical study (Wickramasekera II & Szlyk, 2003) and detail our attempt to replicate these findings in our laboratory. We did not obtain statistically significant relationships between empathic ability and hypnotizability. I discuss these findings, the ramifications on the proposed empathy/hypnotizability question, and the larger agenda of whether hypnotizability connects with personality.
Interaction of Barotropic Vortices with Coastal Topography: Laboratory Experiments and Numerical Simulations

The interaction of a barotropic cyclonic vortex on a b plane with a strong topographic slope is studied by means of laboratory experiments and numerical simulations. In the laboratory, the vortex is produced in a rectangular rotating tank with a weak uniformly sloping bottom (slope angle 3.58) in order to simulate the b effect. The cyclonic vortex moves in the northwestward direction and interacts with an additional, pronounced linear topography (slope angle 358) along the western boundary of the tank. The laboratory experiments revealed that the original northwestward trajectory changes to the south until the vortex is dissipated by viscous effects and bottom friction. As it moves upslope, the exterior ring of the vortex forms a strong current to the northeast. From this current a new cyclonic vortex is created, repeating approximately the behavior of the original one. Later, two more vortices are formed in the same way. A finite difference numerical model is used to solve the nondivergent barotropic equation. Despite the presence of the strong slope, agreement between laboratory results and numerical runs suggests that conservation of potential vorticity is indeed the basic mechanism involved in the southward motion of the vortex and the northeastward meandering current.
Modeling an Analytic Hierarchy Process (AHP) assessment system for municipalities in Greece with public accounting of austerity

The new form of local government organization should be competent and effective in order to provide 21st century services equivalent to the citizens of every country. Its new developmental role can be fulfilled by implementing management techniques that will be conducive to local development. The use of accounting ratios from financial statements is necessary to municipalities as well as to every accounting body to depict the dynamic and static condition of each entity. The aim of the study is to propose a new modeling of an Analytic Hierarchy Process (ΑHP) assessment system for municipalities in Greece based on their public accounting data in the era of austerity, due to the recent Greek economic crisis. Several revenues ratios were analyzed, which were obtained by public accounting data, of a small sample of Greek municipalities with similar population for the years 2011-2015, which is during the period of economic crisis and after the implementation of the “Kallikratis” program in Greece. The analysis of accounting ratios shows useful findings on the efficiency of each one of the examined municipalities. The created assessment model could be applied as a guide in the analysis of financial statements with ratios of all the municipalities in Greece or elsewhere. It could be further used as an evaluation tool by the policy makers and managers in the central state authorities or the municipalities system. Key words: Public accounting, ratios, revenues, municipality, Kallikratis.
Do dividends signal information about future earnings?

This article aims to examine the extent to which dividends signal information about future earnings. It examines the effects of dividend payment status and the change in dividend payment on the relation between current stock returns and future earnings. The results show that dividends contain value relevant information about future earnings and that this information is incorporated into current stock returns. In particular, we find that firms that pay dividends at the current year exhibit higher levels of share price anticipation of earnings than nondividend-paying firms. We also find that the change in dividends is positively related to changes in the importance of future earnings news for current stock returns. Finally, we find that the relevance of dividends for forecasting future earnings is greater for loss-making firms than for profitable firms.
Impact of stratospheric major warmings and the quasi‐biennial oscillation on the variability of stratospheric water vapor

Based on simulations with the Chemical Lagrangian Model of the Stratosphere for the 1979–2013 period, driven by the European Centre for Medium‐Range Weather Forecasts ERA‐Interim reanalysis, we analyze the impact of the quasi‐biennial oscillation (QBO) and of Major Stratospheric Warmings (MWs) on the amount of water vapor entering the stratosphere during boreal winter. The amplitude of H2O variation related to the QBO amounts to 0.5 ppmv. The additional effect of MWs reaches its maximum about 2–4 weeks after the central date of the MW and strongly depends on the QBO phase. Whereas during the easterly QBO phase there is a pronounced drying of about 0.3 ppmv about 3 weeks after the MW, the impact of the MW during the westerly QBO phase is smaller (about 0.2 ppmv) and more diffusely spread over time. We suggest that the MW‐associated enhanced dehydration combined with a higher frequency of MWs after the year 2000 may have contributed to the lower stratospheric water vapor after 2000.
Burden and spectrum of neonatal surgical diseases in a tertiary hospital: a decade experience

Background: Surgical emergencies in the newborns are an important and integral part of neonatal admissions in any tertiary Neonatal intensive care units. Surgical emergencies in the newborn constitute congenital anomalies and acquired neonatal emergencies. It is necessary to know the burden of these illnesses and their spectrum by regular auditing the data available to understand the relative incidence and outcome of these neonatal emergencies. Aims and objective of the study is to determine the spectrum of the different neonatal surgical emergencies (congenital and acquired) admitted, operated and managed in a tertiary NICU from June 2001 to May 2011(10 yrs) in a medical college teaching hospital in South India Methods: The data was collected by retrospectively auditing the hospital pediatric and neonatal admission registry, neonatal surgical registry, admission case sheets from June 2001 to June 2011 (10 yrs). Data was analysed. Only confirmed post-operative surgical diagnosis were considered for inclusion in the study. Results: Of the 13,118 newborns admitted in the NICU in 10 years, 601 cases (4.6%) were surgical neonates which were treated in the unit. 83.5% of surgical neonates were operated for congenital surgical disorders. Gastrointestinal anomalies (50%) were the leading causes of neonatal surgical emergencies. Anorectal malformations (18.5%), idiopathic hypertrophic pyloric stenosis (10.6%) and esophageal atresia with/without tracheo-esophageal fistula (8.7%) were the leading surgical causes which needed immediate surgical intervention in the newborn period. 28 different spectrum of cases were operated including 15 rarer once (<1% incidence each). Conclusions: Surgical new-borns comprises of an important and integral part of neonatal admissions (4.6/100 neonatal admissions). The incidence of the rarer diseases constitutes 8% of the total surgical cases. Gastrointestinal anomalies are the leading causes requiring surgical interventions in the immediate newborn period. It is worthy to understand the spectrum of illnesses in any tertiary unit by regularly auditing the data available.
Population-based variation in resilience to hyposalinity stress in Halophila johnsonii

Plants of the threatened seagrass, Halophila johnsonii Eiseman, from a riverine and marine population were exposed to a series of salinity treatments within mesocosms. Survival and maximum photochemical efficiencies of PSII (Fv/Fm) were measured in response to varied frequency, duration, and amplitude of hyposalinity exposures. Both populations exhibited high survival after two cycles of short, pulsed hyposalinity treatments (100% and 89%, respectively). However, two cycles of long pulses of low salinity resulted in 100% mortality for marine H. johnsonii and >50% mortality for riverine plants. After two cycles of gradual salinity reduction to a salinity of 5, survival for marine and riverine plants was also low (22% and 33%, respectively). Fv/Fm values of riverine H. johnsonii were relatively high (0.65-0.70) after a single short pulse or gradual reduction to salinity of 10. Fv/Fm values of marine plants were lower in these two treatments and exhibited greater declines following a single, long pulse to a salinity of 10 or after a single gradual reduction to a salinity of 5. Fv/Fm values showed riverine plants were also more resistant to repeated pulses of moderate low salinity than marine plants. Our results indicate wide tolerances of H. johnsonii to short pulses of hyposalinity, but suggest that repeated or prolonged hyposalinity stress at near-tolerance salinity levels can have additive effects on photosynthetic health and survival. Differences in resilience of marine and riverine H. johnsonii populations are consistent with previous suggestions that estuarine ecophenes are more tolerant to hyposalinity than marine populations.
Physiological and Physical Quality of Seeds from Peanut Seeds and Plants under the Influence of Fertilizer and Biostimulant

The foliar application and seed Ca + B, Mo + P and Stimulate? in peanut, despite being a practice used long ago, few studies have conclusive results, and then this research was to evaluate the physical and physiological quality peanut seeds from the process of application of fertilizers and bio-stimulant. The design was completely randomized, with seed from peanut plants subjected to the use of three products (Ca + B; Mo + P and Stimulate? ), two types of applications (via leaf and seeds), growing with PK and absolute control, following a factorial arrangement of [(3 × 2) + 2]. For the dimensions (length and width) of seeds, as well as the thousand seed weight and number of seeds per pod, data were submitted to descriptive statistics, calculating the mean, standard deviation, variance and coefficient of variation of the data obtained. The application of fertilizers, bio-stimulants and groundnut seeds increases germination of seeds produced, causes more seedlings that are vigorous and reduces the percentage of abnormal seedlings.
Study on the behavior of finished cost elements of sold product and its effect on costs stickiness in companies listed in Tehran Stock Exchange

One of the complex problems for financial managers is the relationship between profit and efficiency of firm and reduction of costs. Identifying the cost behavior is one of the important discussions in finished cost accounting and management accounting. In traditional costs models in management accounting, variable costs increase or decrease regarding the volume of activity. This means that the largeness of changes is only depends on changes in activity volume and direction of changes in activity volume has no effect on the largeness of changes in costs. The main purpose of this research is studying the behavior of each finished cost elements of sold good and sale costs, general and administrative costs and their effect on the cost stickiness in the firms. In order to verify the hypotheses, multivariate regression method was used. Results of hypotheses testing show that elements of finished costs (including production factor costs i.e. direct material, direct wage and production overhead) has no stickiness relative to ale variations; but sale costs, general and administrative costs have stickiness relative to sale variation. Results indicate that for 1% increase in sale, cost of direct material reduces by 0.025%, cost of direct wage increases by 0.32% and overhead costs increases by 0.003%; but for 1% increase in sale, sale costs, general and administrative costs increase by 502% ad by 1% decrease in sale, sale, general and administrative costs reduces by 0.42%. This means that for 1% reduction in sale, sale, general and administrative costs has 0.042% stickiness.
Newly introduced strawberry genotypes for Nordic Baltic conditions

Kikas A. , Arus L. , Kaldmäe H. , Libek A.V. (2017): Newly introduced strawberry genotypes for Nordic Baltic conditions. Hort. Sci. (Prague), 44: 141–147. Eight recently introduced strawberry genotypes ‘Chambly’, ‘Clery’, ‘Darselect’, ‘Delia’, ‘Harmonie’, ‘Matis’, ‘Sallybright’, ‘Salsa’ and ‘Senga Sengana’ (standard cultivar) were evaluated at the Polli Horticultural Research Centre of the Estonian University of Life Sciences, Institute of Agricultural and Environmental Sciences. Phenology, winter hardiness, strawberry blossom weevil (Anthonomus rubi) injury, yield, fruit weight, soluble solids, sugar, acid and ascorbic acid content of the fruit were determined. Genotypes more suited to the Estonian climate conditions are the winter hardy, late-yielding cultivars ‘Salsa’ and ‘Harmonie’. ‘Salsa’ has a good, high quality yield with large attractive fruit. The fruit of ‘Harmonie’ contains much ascorbic acid, but the sugar-acid ratio is less balanced. Early genotypes ‘Chambly’, ‘Clery’, ‘Darselect’, ‘Delia’, ‘Sallybright’ and the late genotype ’Matis’ have a lower yield than the standard cultivar ‘Senga Sengana’.
Bottom up Approach Toward Prediction of Effective Thermophysical Properties of Carbon-Based Nanofluids

ABSTRACT Carbon-based nanofluids, mainly suspensions of carbon nanotubes or graphene sheets in water, are typically characterized by superior thermal and optical properties. However, their multiscale nature is slowing down the investigation of optimal geometrical, chemical, and physical nanoscale parameters for enhancing the thermal conductivity while limiting the viscosity increase at the same time. In this work, a bottom up approach is developed to systematically explore the thermophysical properties of carbon-based nanofluids with different characteristics. Prandtl number is suggested as the most adequate parameter for evaluating the best compromise between thermal conductivity and viscosity increases. By comparing the Prandtl number of nanofluids with different characteristics, promising overall performances (that is, nanofluid/base fluid Prandtl number ratios equal to 0.7) are observed for semidilute (volume fraction ⩽ 0.004) aqueous suspensions of carbon nanoparticles with extreme aspect ratios (larger than 100 for nanotubes, smaller than 0.01 for nanoplatelets) and limited defects concentrations (<5%). The bottom up approach discussed in this work may ease a more systematic exploration of carbon-based nanofluids for thermal applications, especially solar ones.
Decoupled lake history and regional moisture availability in the middle elevations of tropical Mexico

During the Holocene, most of the climatic variability in the tropics has manifested through changes in the precipitation regime. Although there is relatively a large amount of information on this climatic variability from the lowlands during this time period, little is known regarding the environmental variability in the middle elevations. Here we present evidence of environmental change from a lacustrine sedimentary record recovered from Lake Lacandon, a small shallow water body located in the middle elevations of Chiapas, Mexico. Through analyses of cladoceran assemblages and chemical properties of the sediments (concentrations of C, Ca, N, Rb, Sr, Ti, and Zr), we aimed to reconstruct local and regional environmental conditions during the last 4,000 years. Our results show a highly dynamic cladoceran community apparently associated with changes in the size of the lake, which although variable has been enlarging through the last 4,000 years. Geochemical evidence also suggests high variability in moisture availability overimposed on a general trend towards drier conditions. Whereas the growing lake size seems associated with decreasing insolation seasonality, the trend to drier regional climates corresponds to the well-known southward displacement of the Intertropical Convergence Zone through the Holocene. Although the regional climate has been deteriorating, the enlarging lake suggests a decreasing water deficit though time. This pattern is probably a result of increasing insolation during the dry season, causing advection of marine moisture that precipitates because of the steep elevation gradient. Our results highlight the intricate nature of the millennial scale environmental variability, and the potential role of the middle elevations for sheltering biodiversity through times of environmental hardship.
Comparison of construction equipment emissions for seven construction projects

This paper reports on the results of field studies of seven transportation infrastructure projects. The results of two road projects are compared to four street and utility projects and to a commercial building project. The study results show that road construction emits a much higher quantity of emissions than building construction; that the emissions calculated with published data are higher than those from field data; and that backhoes, motor graders, and bulldozers produce the highest total emissions. This paper adds to our understanding of emissions estimates from multiple project types and data sources.