Miracle-dz/UniFAR-FTUs huggingface dataset:
The use of passive injectable transponders in fattening lambs from birth to slaughter: effects of injection position, age, and breed.

A total of 1,159 Tiris half-duplex passive injectable transponders (PIT) of 32-mm length were used to study the electronic identification of 618 fattening lambs of two breeds used for different production purposes (Ripollesa, meat breed, n = 271, and Manchega, dairy breed, n = 347). The lambs were s.c. injected in the armpit and the retro-auricular positions at 2, 15, and 30 d of age. All lambs were also tagged with a small plastic ear tag after birth. A group of 76 lambs were injected only in the right armpit and were kept for breeding. The PIT losses, breakages, and electronic failures were evaluated at weekly weight recordings throughout the fattening period using two types of hand-held transceivers. Fattened lambs were harvested in a commercial abattoir between 3 and 4 mo of age when they reached market weight (11 to 12 kg hot carcass weight). The total number of PIT that fell or broke in the slaughtering line, the location method, and the recovery time were recorded. On the farm PIT losses were not affected (P > 0.05) by age at injection, injection position, or breed. Mean losses of PIT and ear tags during the same period were 5% and 6.3%, respectively (P > 0.05). No PIT breakages or failures were observed during the fattening period. Mean recovery of PIT in the abattoir (85.6%) was affected (P < 0.05) by breed and injection position. Losses of PIT in the abattoir were greater (P < 0.05) in the Ripollesa breed (18.4%) than in Manchega (10.0%), and for both breeds losses were greater (P < 0.05) in the retro-auricular than in the armpit positions (18.6 vs 10.8%, respectively). The percentage of PIT broken during slaughtering was low (0.3%). The mean recovery times (18 +/- 2 s) were not affected (P > 0.05) by breed, injection position, or age, thus allowing a harvesting speed of 200 lambs/h on average. In conclusion, the injection of 32-mm PIT into the armpit or the retro-auricular region is not recommended as a practice for the electronic identification of fattening lambs, even though they perform similarly to small plastic ear tags. This is partly a consequence of the PIT losses observed on the farm but mainly because of the difficulties with recovering the PIT in the abattoir. More research will determine whether the use of smaller transponders or injection in other positions could improve their performance in fattening lambs.
Nosocomial bacterial meningitis.

Nosocomial bacterial meningitis is most often related to either complicated head trauma or invasive procedures, such as craniotomy, placement of ventricular catheters, intrathecal infusion of medications, or spinal anesthesia. In addition, metastatic infection from hospital-acquired bacteremia occasionally leads to meningitis. The conditions are associated with different pathogenetic mechanisms and a different spectrum of microorganisms, and therefore the choice of empirical antimicrobial therapy will vary according to the condition.
Association of energy and fat intake with prostate carcinoma risk: results from The Netherlands Cohort Study.

BACKGROUND The roles of energy and fat intake as risk factors for prostate carcinoma are still questionable. Therefore, these factors were evaluated in the Netherlands Cohort Study described in this article. METHODS The cohort study consisted of 58,279 men ages 55-69 years at baseline in 1986. After 6.3 years of follow-up, 642 incident prostate carcinoma cases were available for analysis. Intake of energy, fat, and separate fatty acids were measured by means of a self-administered questionnaire; fat intake was adjusted for energy by regression analysis. The case-cohort method was used to calculate rate ratios (RRs). Analyses were conducted for all prostate carcinoma cases together as well as for case subgroups (latent vs. nonlatent and localized vs. advanced). RESULTS No associations were found in multivariate analyses between prostate carcinoma and intake of energy, total fat, total saturated fatty acids, or total trans unsaturated fatty acids (RR highest vs. lowest quintile: 0.99, 1.10, 1.19, and 0.99, respectively). Oleic acid intake showed a nonsignificant positive association (RR = 1.38, 95% CI: 0.88-2.19). Positive associations were also observed for intake of oleic acid in subgroup analyses. Linoleic (RR = 0.78, 95% CI: 0. 56-1.09) and linolenic (RR = 0.76, 95% CI: 0.66-1.04) acid intake were associated with nonsignificantly decreased risks; only for linolenic acid did these associations persist in subgroup analyses. No associations were found for intake of arachidonic acid, eicosapentaenoic acid, or docosahexaenoic acid. CONCLUSIONS These data suggest that certain fatty acids might be involved in prostate carcinoma occurrence, although the possibility that these were chance findings cannot be ruled out.
Wage Adjustment Under Low Inflation: Evidence from U.S. History

Data from recent years indicate that employers are especially unlikely to cut the nominal wage rate paid for a job. Adjustments to real or relative wages that require absolute cuts in money wages are very rare, relative to the frequency one might expect to observe based on distributions of wage changes that do not require money wage cuts (Erica L. Groshen and Mark E. Schweitzer, 1995, 1997; David E. Lebow et al., 1999). A worker who remains with the same employer from one year to the next is accordingly unlikely to report an absolute reduction in the nominal wage he receives (David Card and Dean Hyslop, 1997; Shulamit Kahn, 1997; Joseph G. Altonji and Paul J. Devereux, 1999). The existence and causes of “downward nominal wage rigidity” have implications for macroeconomic outcomes and for practical issues in monetary policy. Presumably, efficient operation of labor markets requires many downward adjustments of relative wages, and occasional decreases in the overall wage level relative to product prices. If the average rate of wage inflation were close to zero, some of these relative or real wage adjustments would be blocked by a floor under current levels of nominal wage rates. George A. Akerlof et al. (1996) assert that downward nominal wage rigidity reflects fundamental preferences of workers, and argue that it implies a central bank should target a rate of price inflation greater than zero because “a target of zero inflation will impose permanent real costs on the economy” (p. 2). The notion that downward nominal wage rigidity is a fundamental constraint, so that inflation serves to “grease the wheels of the labor market,” is controversial even among those who accept the possibility of nominal rigidities in general. It has been argued that downward nominal wage rigidity, as distinct from such phenomena as “menu costs” [which would discourage adjustment of a wage in either direction (David Romer, 1993)], may be an artifact of an inflationary monetary regime, and would disappear in the absence of persistent inflation. “Nominal wage reductions would no longer be seen as unusual if the average nominal wage was not growing. Workers would not see them as unfair, and firms would not shy away from imposing them” (Robert J. Gordon, 1996, p. 62; see also N. Gregory Mankiw, 1996; William Poole, 1998; William B. English, 2000). To see whether downward nominal wage rigidity would exist in a noninflationary regime, it may be useful to examine data from times and places where there was no persistent wage inflation. For the United States, at least, that excludes data from years since the Second World War: throughout the postwar period, price inflation or real wage growth has been sufficient to keep average wage inflation above zero. Before the Second World War, on the other hand, long-run trend rates of price inflation were often close to zero or negative (Robert B. Barsky, 1987). If wage inflation was correspondingly low, U.S. historical data may offer tests of the proposition that downward nominal wage rigidity exists even in noninflationary
Investor Protection and the Mode of Acquisition: Implications for Ownership Dilution and Formation of Pyramids

This paper examines the influence of investor protection on the form of M&A transaction and its subsequent impact on ownership dilution and creation of corporate pyramids. In a large sample of acquisitions around the world, I find that (stock-based) mergers are more likely in countries with good investor protection, while (cash-based) control transactions are more prevalent in countries with low investor protection. Repeated acquisitions in common law countries results in substantial dilution of proportional ownership especially in U.S. but not in civil law countries. In contrast, series of acquisitions in civil law countries linked through firms that are bidders in one acquisition but targets in another tend to generate a corresponding series of inter-corporate control links, while this correspondence is much weaker in common law countries. These results suggest that differences in acquisition modes could be one potential channel through which investor protection affects corporate control structures around the world.
The 50 distal amino acids of the 2AHP homing protein of Grapevine fanleaf virus elicit a hypersensitive reaction on Nicotiana occidentalis.

Avirulence factors are critical for the arm's race between a virus and its host in determining incompatible reactions. The response of plants to viruses from the genus Nepovirus in the family Secoviridae, including Grapevine fanleaf virus (GFLV), is well characterized, although the nature and characteristics of the viral avirulence factor remain elusive. By using infectious clones of GFLV strains F13 and GHu in a reverse genetics approach with wild-type, assortant and chimeric viruses, the determinant of necrotic lesions caused by GFLV-F13 on inoculated leaves of Nicotiana occidentalis was mapped to the RNA2-encoded protein 2AHP , particularly to its 50 C-terminal amino acids. The necrotic response showed hallmark characteristics of a genuine hypersensitive reaction, such as the accumulation of phytoalexins, reactive oxygen species, pathogenesis-related protein 1c and hypersensitivity-related (hsr) 203J transcripts. Transient expression of the GFLV-F13 protein 2AHP fused to an enhanced green fluorescent protein (EGFP) tag in N. occidentalis by agroinfiltration was sufficient to elicit a hypersensitive reaction. In addition, the GFLV-F13 avirulence factor, when introduced in GFLV-GHu, which causes a compatible reaction on N. occidentalis, elicited necrosis and partially restricted the virus. This is the first identification of a nepovirus avirulence factor that is responsible for a hypersensitive reaction in both the context of virus infection and transient expression.
Homology modelling of CYP3A4 from the CYP2C5 crystallographic template: analysis of typical CYP3A4 substrate interactions

1. The results of homology modelling of cytochrome P4503A4 (CYP3A4), which is a human enzyme of major importance for the Phase 1 metabolism of drug substrates, from the CYP2C5 crystal structure is reported. 2. The overall homology between the two protein sequences was generally good (46%) with 24% of amino acid residues being identical and a 22% similarity between matched pairs in the CYP3A4 and CYP2C5 aligned sequences, thus indicating that CYP2C5 represents a viable template for modelling CYP3A4 by homology. 3. The CYP3A4 model appears to show consistency with the reported findings from the extensive site-directed mutagenesis studies already published. 4. Typical CYP3A4 substrates, such as midazolam, testosterone, nifedipine and verapamil, are shown to fit the putative active site of the enzyme structure in a manner consistent with their known positions of metabolism.
Prevalence of atopic disorders among adolescents in Turku, Finland

A study of the prevalence atopic disorders among 15–16‐year‐old teenagers was carried out in a coastal urban town in south‐western Finland. Altogether, 1712 children were found in that age group, all previously examined by a pediatrician. Each child who had present or previous allergic diseases was invited for a detailed study, a total of 434 (25%) pupils. Of these patients 416 (95.8%) participated in clinical examination and skin testing. The prevalence of atopic diseases was 21% in the studied group; atopic eczema was found in 9.7%, allergic rhinitis in 14%, and asthma in 2.5%. Of subjects who had rhinitis, 38% also had atopic eczema, while rhinitis ‐ as the only symptom ‐was found in 8.8%. Figures obtained from this survey suggest that the prevalence rates of atopic diseases are about the same as found 10 years age in Finland and they correspond also with other recent reports.
The informational value of Toxics Release Inventory performance

Purpose – The study aims to evaluate the informational value to investors of the Toxics Release Inventory (TRI) as an external outcome measure of corporate environmental performance. Emphasis is placed on the market response differences between three highly polluting industries.Design/methodology/approach – The study uses pooled cross‐sectional, time‐series data and an event study methodology to examine the effects of TRI emissions on abnormal market returns.Findings – There is empirical evidence that market reactions to TRI emissions information vary by industry. Investors reward decreases in emissions in the electric utility industry, but do not penalize increases. In the chemical industry, increases in emissions are penalized, but decreases are not rewarded. Models do not capture any reaction to emissions changes in the pulp and paper industry. These results may be explained by the significant difference between industries in the US percentage of total firm sales.Research limitations/implications – Thi.
Foreign body giant cells and osteoclasts are TRAP positive, have podosome‐belts and both require OC‐STAMP for cell fusion

Macrophages have the ability to fuse and form multinucleated giant cells such as Osteoclast (OCs) and FBGCs. Osteoclast stimulatory transmembrane protein (OC‐STAMP) is an important cell surface protein involved in the formation of OCs. This study sought to determine if OC‐STAMP also regulates formation of FBGCs using expression analysis and subsequent inhibition studies. qPCR and Western blot analysis showed that OC‐STAMP expression is significantly higher in FBGCs compared to control monocytes (P < 0.05). Four days following cell culture, OCs were positive for TRAP and F‐actin ring formation, but FBGCs were not. In contrast, FBGCs were positive for TRAP and showed podosome belts comprised of F‐actin on Day 8. FBGCs were subsequently plated onto dentine, but despite presenting some morphologic features of OCs (OC‐STAMP expression, TRAP reactivity, and podosome belts) they failed to resorb bone. To evaluate a role for OC‐STAMP in FBGCs, we inhibited this cell surface protein with anti‐OC‐STAMP antibody and observed that cell fusion and podosome belt formation was inhibited in both OCs and FBGCs. Our data support the hypothesis that OC‐STAMP is a regulatory molecule for FBGCs; and that they are functionally distinct from OCs, despite similarities in gene expression profile, podosome belt formation, and TRAP expression. J. Cell. Biochem. 114: 1772–1778, 2013. © 2013 Wiley Periodicals, Inc.
Towards a European System of Labor Relations?

ABSTRACT Are the systems of collective labor relations in member countries of the European Communities converging towards a common European system of industrial relations? In this paper the hypothesis is put forward that the national systems have not been converging in the past and probably will not do so in the immediate future. The analysis is based on changes in procedural rules of collective labor relations and on data on labor unions, strikes, wage structure, and government employment.
The history of welfare and paid maternity leave in Australia

Australia has a long tradition of providing women with welfare payments that correlate with maternity and having children. Since 1912, consecutive Australian governments have opted for welfare payments as opposed to opting for legislating universal paid maternity leave. This paper examines the history of welfare and paid maternity leave in Australia by examining the role maternity related welfare and paid maternity leave have played in the Australian context. Consideration is given to the implications maternity related welfare and paid maternity leave have had from the social, political and economical paradigms. The paper concludes that while it is clear that the provision of maternity welfare payment to families presents some obvious benefits, such as lowering infant mortality, maternity welfare does not take into account the implication that having a child can have upon women in paid employment and women’s ‘dual responsibilities’.
Correlation of IgA, IgM and IgG antibody-detecting assays based on filamentous haemagglutinin, pertussis toxin and Bordetella pertussis sonicate in a strictly adult population

Pertussis diagnosis among adults is primarily based on serology. In this study, receiver operation characteristics (ROC) analysis was utilized to evaluate three IgA, IgM and IgG ELISAs based on B. pertussis whole-cell sonicate (WC), pertussis toxin (PT), or combined PT-filamentous haemagglutinin (FHA) antigens in a healthy adult population and in adults suffering from symptoms consistent with pertussis. The assays were compared to a PT and FHA reference ELISA. The reference assay showed high correlation with PT- and PT-FHA-based ELISAs but low correlation was found with the WC-based ELISA. However, ROC analysis indicated that all the assays enabled fine differentiation between healthy subjects and subjects suffering from symptoms suggestive of pertussis. The WC IgA ELISA showed the best diagnostic performance [highest specificity (98·8%) with highest sensitivity (53·8%)]. We conclude that despite a low correlation between the various assays they all carry good diagnostic capability for an adult population.
Effects of different Helicobacter pylori culture filtrates on growth of gastric epithelial cells.

AIM To study the effects of different Helicobacter pylori (H pylori) culture filtrates on growth of gastric epithelial cells. METHODS Broth culture filtrates of H pylori were prepared. Gastric epithelial cells were treated with the filtrates, and cell growth was determined by growth curve and flow cytometry. DNA damage of gastric epithelial cells was measured by single-cell microgel electrophoresis. RESULTS Gastric epithelial cells proliferated actively when treated by CagA-gene-positive broth culture filtrates, and colony formation reached 40%. The number of cells in S phase increased compared to controls. Comet assay showed 41.2% comet cells in GES-1 cells treated with CagA-positive filtrates (P < 0.05). CONCLUSION CagA-positive filtrates enhance the changes in morphology and growth characteristics of human gastric epithelial tumor cells. DNA damage maybe one of the mechanisms involved in the growth changes.
The psychological antecedents of employee referrals

This study investigates how different psychological antecedents lead to different components of organizational commitment and employee referrals or employment recommendations in a people-based financial services context. Specifically, we consider the impact of position involvement, volitional choice, and informational complexity on affective, calculative, and normative commitment, which ultimately influences employee referrals in the context of a Flemish bank. Our conceptual model is supported through SEM, and the empirical results show differential impacts of the three psychological antecedents on the various components of organizational commitment and employee referrals. Position involvement and affective commitment represent the key determinants of employee referrals. We also address the theoretical and managerial implications of our research.
Taxes, Tariffs and Transfer Pricing in Multinational Corporate Decision Making

Three interrelated aspects of U.S. multinational corporation activity are analyzed here: the ability to shift profits from high-tax countries to low-tax countries; the impact of host country taxes and tariffs on the distribution of real capital; and the influence of these policies on international trade patterns of the United States and host countries. The cross-sectional empirical analysis indicates that the observed pattern of reported profits in high and low-tax countries is consistent with income shifting behavior and that real investment responds to host country effective tax rates and tariffs. The United States appears both to import more from and export more to low-tax countries where MNC investment is greater, but this bilateral focus must be amplified to consider multilateral effects if trade benefits are to be projected. Copyright 1991 by MIT Press.
The Interaction of Global Value Chains and Rural Livelihoods: The Case of Smallholder Raspberry Growers in Chile

This paper integrates aspects of global value chain and sustainable rural livelihoods analyses in an exploration of the local impacts of agri-food globalization in Chile. In particular, it examines the evolution of the raspberry export sector in the context of Chile's non-traditional agricultural export boom, and considers its importance to smallholder growers and rural households in central Chile. The paper first outlines the geography and structural configuration of the global value chain for Chilean raspberries, and considers modes of governance and forms of coordination between key actors within the chain. Second, the terms and implications of smallholder grower participation in the value chain are explored in a discussion of access to key livelihoods assets. The paper concludes that institutional support to smallholders, even in the case of a crop that is widely seen to have a small-scale ‘size bias', remains integral to their capacity to comply with required safety and quality standards and gain and retain market access via the value chain.