Miracle-dz/UniFAR-FTUs huggingface dataset:
The surgeon's view of the anterior ethmoid artery.

OBJECTIVES To define the relationship of the anterior ethmoid artery to the frontal recess and secondly whether the degree of pneumatisation of the suprabullar recess/supraorbital cell correlates with the distance between the anterior ethmoid artery and the skull base thus making it more vulnerable to damage during surgery. METHOD Thirty-four cadaver head sides were perfused with pink latex. All specimens had high-resolution computed tomography (CT) scans using bone windows in the axial, coronal and sagittal planes. The specimen's nasal septum was removed and the ethmoid sinuses dissected to locate the anterior ethmoid artery. Calipers were used to measure distance between the artery and the frontal recess and from the skull base. RESULTS The anterior ethmoid artery was found in all the specimens and scans. The distance between the anterior ethmoid artery and the posterior wall of the frontal recess was 11 mm (range 6-15 mm). In all specimens, the artery was seen between the second and third lamella. The commonest location of the artery was in the suprabullar recess (85.3%). Supraorbital cells were seen in 16 specimens. The ethmoid sinuses were well pneumatised with a large supraorbital cell in 10 of these specimens and in these the artery was lying 3.7 mm (range 1-8 mm) away from the skull base. Six specimens had poor pneumatisation and a small supraorbital cell and in these the artery was found close to or with in the skull base. In specimens without a supraorbital cell, the artery lay at the skull base in all but one. CONCLUSIONS The position of the anterior ethmoidal artery is very variable. The artery is found between the second and third lamella. When the ethmoid sinuses are more pneumatised and in particular when there is a supraorbital cell, the artery lies below the skull base. A good strategy is to identify the degree of pneumatisation of the ethmoid sinuses from CT scans preoperatively to see if the artery is at an increased risk of being damaged.
Profiles of temporary Mexican labor migrants to the United States

Profiles of temporary labor migrants from Mexico to the United States are constructed using Mexican data from a nationwide sample. Commuters are compared with noncommuters and males with females. Characteristics according to region of origin are examined and the profiles from this study are compared with those from two prominent previous surveys. Directions for future research are suggested. (summary in FRE SPA) (EXCERPT)
Effect of arsenic trioxide on vascular endothelial cell proliferation and expression of vascular endothelial growth factor receptors Flt-1 and KDR in gastric cancer in nude mice.

AIM To investigate the effect of arsenic trioxide (As2O3) on expression of vascular endothelial growth factor receptor-1 (VEGFR-1, Flt-1) and VEGFR-2 (KDR) in human gastric tumor cells and proliferation of vascular endothelial cells. METHODS The solid tumor model was formed in nude mice with the gastric cancer cell line SGC-7901. The animals were treated with As2O3. Microvessel density (MVD) and expression of Flt-1 and KDR were detected by immunofluorescence laser confocal microscopy. SGC-7901 cells were treated respectively by exogenous recombinant human VEGF165 or VEGF165 + As2O3. Cell viability was measured by MTT assay. Cell viability of ECV304 cells was measured by MTT assay, and cell cycle and apoptosis were analyzed using flow cytometry. RESULTS The tumor growth inhibition was 30.33% and 50.85%, respectively, in mice treated with As2O3 2.5 and 5 mg/kg. MVD was significantly lower in arsenic-treated mice than in the control group. The fluorescence intensity levels of Flt-1 and KDR were significantly less in the arsenic-treated mice than in the control group. VEGF165 may accelerate growth of SGC7901 cells, but As2O3 may disturb the stimulating effect of VEGF165. ECV304 cell growth was suppressed by 76.51%, 71.09% and 61.49% after 48 h treatment with As2O3 at 0.5, 2.5 and 5 micromol/L, respectively. Early apoptosis in the As2O3-treated mice was 2.88-5.1 times higher than that in the controls, and late apoptosis was 1.17-1.67 times higher than that in the controls. CONCLUSION Our results showed that As2O3 delays tumor growth, inhibits MVD, down-regulates Flt-1 and KDR expression, and disturbs the stimulating effect of VEGF165 on the growth of SGC7901 cells. These results suggest that As2O3 might delay growth of gastric tumors through inhibiting the paracrine and autocrine pathways of VEGF/VEGFRs.
Comparison of Different Speech Coding Strategies Using a Disability-Based Inventory and Speech Perception Tests in Quiet and in Noise

Objective Intraindividual comparison of two cochlear implant speech coding strategies implemented in the Nucleus 24M system (SPEAK versus ACE). Reasons for subjective preference were evaluated using a combination of speech perception scores and a disability-based inventory. Study Design Cross-over study with two groups of cochlear implant subjects, assigned to first receive ACE or SPEAK strategy. Setting Cochlear implant program. Subjects Twelve postlingually deaf adults using a Nucleus 24M cochlear implant system. Intervention Subjects consecutively used the two different speech coding strategies and completed speech perception tests in quiet and in noise and a disability-based inventory (Abbreviated Profile of Hearing Aid Benefit). Main Outcome Measures Individual differences between the two different speech coding strategies and the relation with subjective strategy preference. Results The ACE strategy produced somewhat better speech recognition scores in quiet and in noise, although the difference in the scores in noise did not reach the 95% level of significance. The first coding strategy chosen did not affect the results or subjective preference. Preference according to the APHAB results were not a priori in conformity with the speech recognition scores. Conclusion Most subjects preferred the ACE strategy. Subjective preference was in agreement with the APHAB results in three subjects, in agreement with speech recognition in two subjects, and in agreement with both in seven subjects. The present results support the use of both speech recognition tests and questionnaires to evaluate different speech coding strategies.
Caring for the dead? An alternative perspective on Sámi reburial

ABSTRACT This article is an effort to critically discuss Sámi repatriation and reburial practice based on the analysis of five repatriation cases. Since the seminal repatriation (and burial) of the skulls of Somby and Hætta in Gávvuonna/Kåfjord in 1997, and the more recent reburial of 94 skeletons in Njauddâm/Neiden in 2011, a precedent seems established in Norway that allows the unconditional reburial of all Sámi human remains from collections and excavations. This inevitably poses a serious challenge to research on Sámi human remains and the Sámi past. It is argued that what is important is not research, but that Sámi are allowed to decide for themselves how they wish to care for the dead. Rather than argue according to the adversarial pro-research or pro-reburial viewpoints, this article will take a closer look at how the dead, and their associated material remains, are cared for during Sámi reburial. As will be argued, the care for the material side tends to be neglected and therefore raises an ethical question regarding this practice.
Effects of Adding Polysaccharides and Citric Acid into Sodium Dihydrogen Phosphate Mixing Solution on the Material Properties of Gelatin-Hybridized Calcium-Phosphate Cement

We have succeeded in improving the material properties of a chelate-setting calcium-phosphate cement (CPC), which is composed of hydroxyapatite (HAp) the surface of which has been modified with inositol hexaphosphate (IP6) by adding α-tricalcium phosphate (α-TCP) powder. In order to create a novel chelate-setting CPC with sufficient bioresorbability, gelatin particles were added into the IP6-HAp/α-TCP cement system to modify the material properties. The effects of adding polysaccharides (chitosan, chondroitin sulfate, and sodium alginate) into the sodium dihydrogen phosphate mixing solution on the material properties of the gelatin-hybridized CPC were evaluated. The results of mechanical testing revealed that chondroitin sulfate would be the most suitable for fabricating the hybridized CPC with higher compressive strength. Moreover, further addition of an appropriate amount of citric acid could improve the anti-washout capability of the cement paste. In summary, a gelatin-hybridized IP6-HAp/α-TCP cement system prepared with a mixing solution containing chondroitin sulfate and citric acid is expected to be a beneficial CPC, with sufficient bioresorbability and material properties.
Real-Time Imaging of Gap Progress during and after Composite Polymerization

The aims of this study were to observe the behavior of composite and formation of gaps during and immediately after light polymerization using swept source optical coherence tomography (OCT) and to compare the interfacial integrity of adhesives in cavities through 3-dimensional (3D) image analysis. Forty tapered cylindrical cavities (4-mm diameter, 2-mm depth) were prepared in bovine incisors and restored using Bond Force (BF), Scotchbond Universal Adhesive (SBU), OptiBond XTR (XTR), or Clearfil SE Bond 2 (SE2), followed by Estelite Flow Quick flowable composite. Real-time imaging was performed at the center of restoration by the OCT system (laser center wavelength: 1,330 nm; frequency: 30 KHz) during and up to 10 min after light curing. The 3D scanning was performed 0, 1, 3, 5, and 10 min after light curing. The percentages of sealed enamel and dentin interface area (E%, D%) were calculated using Amira software. In real-time videos, the initial gaps appeared as a bright scattered area mainly on dentin floor and rapidly progressed along the cavity floor. The timing, rate, and extent of gap formation were different among the specimens. From 3D visualization, gap progress could be seen on both enamel and dentin even after irradiation; furthermore, typical toroidal gap patterns appeared at the dentin floor of BF and SBU. XTR and SE2 showed nearly perfect sealing performance on the dentin floor up to the 10 min that images were recorded. From quantitative analysis, SE2 and XTR showed significantly higher E% and D% than other groups. SBU showed the smallest E% and BF showed a significantly smaller D% than other groups (P < 0.05). In conclusion, real-time observation of composite placement and 3D quantification of interfacial gaps were implemented within the experimental limitations. Interfacial gap formation during polymerization of the composite depended on the adhesive system used. The formed gaps continued to propagate after composite light curing finished.
The Perfect Ocean for Drought

The 1998–2002 droughts spanning the United States, southern Europe, and Southwest Asia were linked through a common oceanic influence. Cold sea surface temperatures (SSTs) in the eastern tropical Pacific and warm SSTs in the western tropical Pacific and Indian oceans were remarkably persistent during this period. Climate models show that the climate signals forced separately by these regions acted synergistically, each contributing to widespread mid-latitude drying: an ideal scenario for spatially expansive, synchronized drought. The warmth of the Indian and west Pacific oceans was unprecedented and consistent with greenhouse gas forcing. Some implications are drawn for future drought.
High dose chemotherapy with bone marrow or peripheral stem cell rescue is an effective treatment option for patients with relapsed or progressive Ewing's sarcoma family of tumours.

BACKGROUND The outcome for patients with recurrent or progressive Ewing's sarcoma family of tumours (ESFT) is poor. High dose therapy (HDT) has been used for a number of years in an attempt to improve survival; however, evidence for the efficacy of this treatment remains limited. PATIENTS AND METHODS Between 1992 and 2004, 33 patients with recurrent or progressive ESFT were treated with HDT with bone marrow (n=2), peripheral blood stem cell (n=30), or bone marrow and peripheral blood stem cell support (n=1), at a single institution. HDT was with busulphan and melphalan in 22 patients; melphalan and etoposide in seven patients, three with total body irradiation (TBI); melphalan in three patients (2 with TBI), and busulphan and cyclophosphamide in one patient. RESULTS The 2 and 5 year event free survival was 42.5% (95% CI, 26-59%) and 38.2% (95% CI, 21-55%) respectively. There was one treatment related death from colitis, and grade 4 infection was observed in two patients. CONCLUSIONS Long-term survival can be attained in patients with recurrent or refractory ESFT treated with HDT. However, this treatment is associated with severe toxicity. A need remains for prospective randomised clinical trials of HDT in this group of patients.
Growth and Remittance Nexus in the Fiji Islands: An Investigation Using Bounds Test Analysis

In this paper, I study the effect of remittances on economic growth of the Fiji Islands. I provide empirical evidences based on data for the period 1979-2007 that remittances have a positive and significant impact on growth of Fiji’s economy. The investigation also indicates the need to encourage financial sector development and consider furthering remittances inflows through sound policies.
Assessment of Students’ Attitude Towards Agricultural Science Subject in Secondary Schools in Olamaboro Local Government Area of Kogi State, Nigeria

The study assessed factors that influence students’ attitude towards agricultural science subject in secondary schools in Olamaboro Local Government Area of Kogi State, Nigeria. Specifically, the study identified career choice among secondary school students in agriculture; assessed students’ perception of career prospects in agriculture; and identified factors that influence students’ attitude towards agricultural science subject in secondary schools. A three staged random sampling technique was used to select 120 respondents. Structured questionnaire was administered to the sampled respondents for data collection. Data obtained were analyzed using descriptive statistics and mean score from a Likert type of scale. The results revealed that the major areas of interest in agriculture among secondary school students include agricultural engineering (65.8%) and food science (56.7%). Only 2.5% of the respondents were interested in agricultural education as a career. Perceptions of students on career prospects in agriculture were: poor societal value of farmers (M=3.6), tedious nature of agriculture (M=3.2), personal dislike for the profession (M=3.2), and poor wage/income in the profession (M-3.2). However, students’ attitude towards agricultural science subject was influenced by parents’ background, parents’ influence and tedious agricultural practical (M=2.3 respectively). It is recommended that career counselors in different schools should not relent in their efforts by giving proper orientation and awareness on agriculture as a noble and wealth creating profession. Also, funds should be made available to secondary schools for the purchase of modern farming implements such as tractor and other modernized equipment to enable the younger generation develop interest in the profession.
Arabidopsis Transcriptome Changes in Response to Phloem-Feeding Silverleaf Whitefly Nymphs. Similarities and Distinctions in Responses to Aphids1[W][OA]

Phloem-feeding pests cause extensive crop damage throughout the world, yet little is understood about how plants perceive and defend themselves from these threats. The silverleaf whitefly (SLWF; Bemisia tabaci type B) is a good model for studying phloem-feeding insect-plant interactions, as SLWF nymphs cause little wounding and have a long, continuous interaction with the plant. Using the Affymetrix ATH1 GeneChip to monitor the Arabidopsis (Arabidopsis thaliana) transcriptome, 700 transcripts were found to be up-regulated and 556 down-regulated by SLWF nymphs. Closer examination of the regulation of secondary metabolite (glucosinolate) and defense pathway genes after SLWF-instar feeding shows that responses were qualitatively and quantitatively different from chewing insects and aphids. In addition to the RNA profile distinctions, analysis of SLWF performance on wild-type and phytoalexin-deficient4 (pad4) mutants suggests aphid and SLWF interactions with Arabidopsis were distinct. While pad4-1 mutants were more susceptible to aphids, SLWF development on pad4-1 and wild-type plants was similar. Furthermore, although jasmonic acid genes were repressed and salicylic acid-regulated genes were induced after SLWF feeding, cytological staining of SLWF-infested tissue showed that pathogen defenses, such as localized cell death and hydrogen peroxide accumulation, were not observed. Like aphid and fungal pathogens, callose synthase gene RNAs accumulated and callose deposition was observed in SLWF-infested tissue. These results provide a more comprehensive understanding of phloem-feeding insect-plant interactions and distinguish SLWF global responses.
Decreased Level of Cord Blood Circulating Endothelial Colony–Forming Cells in Preeclampsia

Preeclampsia is a pregnancy-related disorder associated with increased cardiovascular risk for the offspring. Endothelial colony–forming cells (ECFCs) are a subset of circulating endothelial progenitor cells that participate in the formation of vasculature during development. However, the effect of preeclampsia on fetal levels of ECFCs is largely unknown. In this study, we sought to determine whether cord blood ECFC abundance and function are altered in preeclampsia. We conducted a prospective cohort study that included women with normal (n=35) and preeclamptic (n=15) pregnancies. We measured ECFC levels in the umbilical cord blood of neonates and characterized ECFC phenotype, cloning-forming ability, proliferation, and migration toward vascular endothelial growth factor-A and fibroblast growth factor-2, in vitro formation of capillary-like structures, and in vivo vasculogenic ability in immunodeficient mice. We found that the level of cord blood ECFCs was statistically lower in preeclampsia than in control pregnancies (P=0.04), a reduction that was independent of other obstetric factors. In addition, cord blood ECFCs from preeclamptic pregnancies required more time to emerge in culture than control ECFCs. However, once derived in culture, ECFC function was deemed normal and highly similar between preeclampsia and control, including the ability to form vascular networks in vivo. This study demonstrates that preeclampsia affects ECFC abundance in neonates. A reduced level of ECFCs during preeclamptic pregnancies may contribute to an increased risk of developing future cardiovascular events.
Can Airborne Laser Scanning (ALS) and Forest Estimates Derived from Satellite Images Be Used to Predict Abundance and Species Richness of Birds and Beetles in Boreal Forest?

In managed landscapes, conservation planning requires effective methods to identify high-biodiversity areas. The objective of this study was to evaluate the potential of airborne laser scanning (ALS) and forest estimates derived from satellite images extracted at two spatial scales for predicting the stand-scale abundance and species richness of birds and beetles in a managed boreal forest landscape. Multiple regression models based on forest data from a 50-m radius (i.e., corresponding to a homogenous forest stand) had better explanatory power than those based on a 200-m radius (i.e., including also parts of adjacent stands). Bird abundance and species richness were best explained by the ALS variables "maximum vegetation height" and "vegetation cover between 0.5 and 3 m" (both positive). Flying beetle abundance and species richness, as well as epigaeic (i.e., ground-living) beetle richness were best explained by a model including the ALS variable "maximum vegetation height" (positive) and the satellite-derived variable "proportion of pine" (negative). Epigaeic beetle abundance was best explained by "maximum vegetation height" at 50 m (positive) and "stem volume" at 200 m (positive). Our results show that forest estimates derived from
Life, activation and death of intrahepatic lymphocytes in chronic hepatitis C

Summary: The healthy liver of adult humans has little or no lymphocyte component and the histological finding of intrahepatic lymphocytes (IHL) is evidence of liver pathology. In a liver injured by chronic hepatitis C, the most common chronic liver disease, most IHL are activated/pro‐inflammatory cells, which are particularly enriched for effectors of innate immunity (natural killer (NK), natural T, and other NK‐like T cells). IHL do not undergo clonal expansion in the liver but migrate from extrahepatic sites to the chronically infected liver, where they display effector function and subsequently die, suggesting that maintenance of the IHL pool depends on continuous lymphocyte migration. The cytotoxic and inflammatory functions of these IHL have three potential outcomes: 1) they could be helpful in clearing the virus (a rare case in hepatitis C virus (HCV) infection); 2) they could be useless and have no effect on the infection; or 3) they could be harmful, whereby overaggressive lymphocyte responses destroy the liver in a continuous and unsuccessful attempt to clear the virus. Unfortunately, we do not know as of yet which of these possibilities is the case and, therefore, a more complete picture of the intrahepatic immune response will be relevant to the development of new therapeutic strategies against HCV. Additionally and from a more general perspective, due to the availability of biopsied material and the high prevalence (~3%) of HCV infection worldwide, studying the chronically inflamed liver of hepatitis C patients is an ideal model to investigate the poorly understood processes of lymphocyte trafficking, activation and death to non‐lymphoid sites of chronic inflammation in man.
The role of email guidance in internet-based cognitive-behavioural self-care treatment for bulimia nervosa.

Email has been progressively used as a means for providing therapeutic guidance and support for cognitive behavioural treatment (CBT) self-care programmes. Many aspects of the use of email in self-care need to be explored such as the content of therapists' emails. Such information would optimise the delivery of self-care treatments. To date no study has looked at the content of the therapists' emails. We analysed the content of emails (n = 712) sent by therapists to participants (n = 71) of a randomised controlled trial (RCT) of internet-based CBT with email support for bulimic disorders. 14.7% of the emails therapists sent contained at least one CBT comment, while 95.4% had at least one supportive comment and 13.6% had at least one technical comment. The mean time spent on providing email support to each participant across the complete programme was 45 minutes. Emails sent by therapists were mainly supportive in content, with only a small amount of time being required by therapists to provide email support.