Miracle-dz/UniFAR-FTUs huggingface dataset:
Chinese-Speaking Learners' Cognitive Comprehension Problems with English Video-Based Materials

This study surveyed the problems 213 university students confronted while viewing an online video-based English program. Data were collected through self-reports and one-to-one interviews. The content analysis approach was used. Totally, 18 problems were identified and categorized into three cognitive-processing stages: perception, parsing, and utilization. Percentages for each problem were calculated for the whole group and for the three English proficiency groups. The whole group results indicated that most comprehension problems occurred at the perception stage, and that the most common perception problem was that the speech rate was too fast. The most common parsing problem was that the participants failed to form a mental representation of what they had heard or read, while the most common utilization problem was that they could not assign the intended meanings to words. Each proficiency group's problems at the three cognitive stages were interpreted. Instructional recommendations to enhance learners' video comprehension are presented.
Balancing model-based and memory-free action selection under competitive pressure

In competitive situations, winning depends on selecting actions that surprise the opponent. Such unpredictable action can be generated based on representations of the opponent’s strategy and choice history (model-based counter-prediction) or by choosing actions in a memory-free, stochastic manner. Across five different experiments using a variant of a matching-pennies game with simulated and human opponents we found that people toggle between these two strategies, using model-based selection used when recent wins signal the appropriateness of the current model, but reverting to stochastic selection following losses. Also, after wins, feedback-related, mid-frontal EEG activity reflected information about the opponent’s global and local strategy, and predicted upcoming choices. After losses, this activity was nearly absent—indicating that the internal model is suppressed after negative feedback. We suggest that the mixed-strategy approach allows negotiating two conflicting goals: (1) exploiting the opponent’s deviations from randomness while (2) remaining unpredictable for the opponent.
N-GRAM-BASED AUTHOR PROFILES FOR AUTHORSHIP ATTRIBUTION

We present a novel method for computer-assisted authorship attribution based on characterlevel n-gram author proles, which is motivated by an almost-forgotten, pioneering method in 1976. The existing approaches to automated authorship attribution implicitly build author proles as vectors of feature weights, as language models, or similar. Our approach is based on byte-level n-grams, it is language independent, and the generated author proles are limited in size. The eectiveness of the approach and language independence are demonstrated in experiments performed on English, Greek, and Chinese data. The accuracy of the results is at the level of the current state of the art approaches or higher in some cases.
A CFOA-Based Voltage-Mode Multifunction Biquadratic Filter and a Quadrature Oscillator Using the CFOA-Based Biquadratic Filter

This paper proposes a new high-input impedance current feedback operational amplifier (CFOA)- based voltage-mode multifunction biquadratic filter and a voltage-mode quadrature oscillator using the proposed high-input impedance CFOA-based biquadratic filter. The proposed high-input impedance CFOA-based voltage-mode multifunction biquadratic filter uses three CFOAs, three resistors, and two grounded capacitors with two inputs and three outputs. The filter can simultaneously realize non-inverting low-pass, non-inverting band-pass, and non-inverting band-reject filtering functions at the high-input impedance terminal while the inverting band-pass and non-inverting high-pass filtering functions can also be obtained by applying another high-input impedance terminal. The filter offers orthogonal control of resonance angular frequency and quality factor. The proposed high-input impedance CFOA-based voltage-mode multifunction biquadratic filter can be used to implement a voltage-mode quadrature oscillator with an independently controlled the frequency of oscillator and the condition of oscillation. The OrCAD PSpice simulation and experimental results of the commercially available integrated circuit, AD844AN, are used to confirm the characteristics of the proposed filter and oscillator.
Video Tutorials in Academic Art Libraries: A Content Analysis and Review

Combining the informative nature of library tutorials with the interactivity of online video, video tutorials and screencasts have become recognized as an effective way to provide instruction in an engaging manner. The visual nature of video makes the medium highly appropriate at institutions serving visual arts researchers, who regularly seek images for edification. This article examines the availability and quality of video tutorials among 290 academic libraries serving arts students, finding that 48 percent of institutions include instructional videos on their Web sites. Increased tutorial development on diverse topics using varied recording methods is recommended based on the results.
ACCURACY ASSESSMENT OF LIDAR-DERIVED DIGITAL TERRAIN MODEL (DTM) WITH DIFFERENT SLOPE AND CANOPY COVER IN TROPICAL FOREST REGION

Airborne Light Detection and Ranging (LiDAR) technology has been widely used recent years especially in generating high accuracy of Digital Terrain Model (DTM). High density and good quality of airborne LiDAR data promises a high quality of DTM. This study focussing on the analysing the error associated with the density of vegetation cover (canopy cover) and terrain slope in a LiDAR derived-DTM value in a tropical forest environment in Bentong, State of Pahang, Malaysia. Airborne LiDAR data were collected can be consider as low density captured by Reigl system mounted on an aircraft. The ground filtering procedure use adaptive triangulation irregular network (ATIN) algorithm technique in producing ground points. Next, the ground control points (GCPs) used in generating the reference DTM and these DTM was used for slope classification and the point clouds belong to non-ground are then used in determining the relative percentage of canopy cover. The results show that terrain slope has high correlation for both study area (0.993 and 0.870) with the RMSE of the LiDAR-derived DTM. This is similar to canopy cover where high value of correlation (0.989 and 0.924) obtained. This indicates that the accuracy of airborne LiDAR-derived DTM is significantly affected by terrain slope and canopy caver of study area.
Surgical Treatments for Canine Anterior Cruciate Ligament Rupture: Assessing Functional Recovery Through Multibody Comparative Analysis

Anterior cruciate ligament (ACL) deficiency can result in serious degenerative stifle injuries. Although tibial plateau leveling osteotomy (TPLO) is a common method for the surgical treatment of ACL deficiency, alternative osteotomies, such as a leveling osteotomy based on the center of rotation of angulation (CBLO) are described in the literature. However, whether a CBLO could represent a viable alternative to a TPLO remains to be established. The aim of this study is to compare TPLO and CBLO effectiveness in treating ACL rupture. First, a computational multibody model of a physiological stifle was created using three-dimensional surfaces of a medium-sized canine femur, tibia, fibula and patella. Articular contacts were modeled by means of a formulation describing the contact force as function of the interpenetration between surfaces. Moreover, ligaments were represented by vector forces connecting origin and insertion points. The lengths of the ligaments at rest were optimized simulating the drawer test. The ACL-deficient model was obtained by deactivating the ACL related forces in the optimized physiological one. Then, TPLO and CBLO treatments were virtually performed on the pathological stifle. Finally, the drawer test and a weight-bearing squat movement were performed to compare the treatments effectiveness in terms of tibial anteroposterior translation, patellar ligament force, intra-articular compressive force and quadriceps force. Results from drawer test simulations showed that ACL-deficiency causes an increase of the anterior tibial translation by up to 5.2 mm, while no remarkable differences between CBLO and TPLO were recorded. Overall, squat simulations have demonstrated that both treatments lead to an increase of all considered forces compared to the physiological model. Specifically, CBLO and TPLO produce an increase in compressive forces of 54% and 37%, respectively, at 90° flexion. However, TPLO produces higher compressive forces (up to 16%) with respect to CBLO for wider flexion angles ranging from 135° to 117°. Conversely, TPLO generates lower forces in patellar ligament and quadriceps muscle, compared to CBLO. In light of the higher intra-articular compressive force over the physiological walking range of flexion, which was observed to result from TPLO in the current study, the use of this technique should be carefully considered.
Pattern of psychiatric referrals to psychiatric unit in a tertiary care medical college

Pattern of psychiatric referrals to psychiatric unit in a tertiary care medical college, p Introduction: nbsp;Psychiatric illness have high comorbidity with other disorders. Referred cases from other departments are the major source of patients to the psychiatry unit. Stigma regarding psychiatry illness, lack of awareness, lack of inter
Phosphate Solubilizing Microorganisms: Promising Approach as Biofertilizers

Phosphorus (P) is a macronutrient required for the proper functioning of plants. Because P plays a vital role in every aspect of plant growth and development, deficiencies can reduce plant growth and development. Though soil possesses total P in the form of organic and inorganic compounds, most of them remain inactive and thus unavailable to plants. Since many farmers cannot afford to use P fertilizers to reduce P deficits, alternative techniques to provide P are needed. Phosphate solubilizing microbes (PSMs) are a group of beneficial microorganisms capable of hydrolyzing organic and inorganic insoluble phosphorus compounds to soluble P form that can easily be assimilated by plants. PSM provides an ecofriendly and economically sound approach to overcome the P scarcity and its subsequent uptake by plants. Though PSMs have been a subject of research for decades, manipulation of PSMs for making use of increasing fixed P in the soil and improving crop production at the field level has not yet been adequately commercialized. The purpose of this review is to widen the understanding of the role of PSMs in crop production as biofertilizers.
Contrast enhancement as motivation for closed syllable laxing and open syllable tensing

This paper proposes that closed syllable laxing and open syllable tensing of non-low vowels are motivated by conflicting strategies of contrast enhancement in vowel–consonant sequences. Laxing enhances the distinctiveness of consonant contrasts by allowing for more distinct VC formant transitions, in particular in sequences involving a non-low vowel followed by an oral labial/coronal/velar consonant (e.g. [p t k]). Tensing enhances the distinctiveness of vowel contrasts by providing more distinct formant realisations for vowels. Linguistic variation results from different ways of resolving the tension between maximising vowel dispersion and maximising consonant dispersion. Laxing typically applies before coda consonants as a way to compensate for the absence of good perceptual cues to place of articulation. The hypothesis that laxing enhances the distinctiveness of postvocalic place contrasts is supported by a study of mid-vowel laxing in French, which corroborates the general claim that perceptual contrast plays a role in shaping phonotactic restrictions.
Agronomic performance of Marandu grass treated with plant growth biostimulants in the Amazon biome

ABSTRACT The aim was to evaluate the effect of different doses of two biostimulants on the productivity and canopy structure of Urochloa brizantha cv. Marandu grass in the establishment fase. The study was conducted in Universidade Federal Rural da Amazônia, Parauapebas, Pará, Brazil. One module of 35 plots of 25m² were established. A completely randomized experimental design was used, with seven treatments and five replicates. The treatments included a control, 0.5, 1, and 2kg/ha of biostimulant A (BIOST.A); and 0.25, 0.5, and 1L/ha of biostimulant B (BIOST.B). Three collections were performed. The data for application of the two biostimulants were analyzed separately, using the Dummy variable method and regression analysis. The application of 2kg/ha BIOST.A resulted in increases of 842kg/ha in the forage mass. The application of BIOST.B on Marandu grass resulted in a linear increase in stem mass. The application of 2kg/ha BIOST.A in the establishment of Marandu grass result in higher growth rates, forage accumulation, and stem proportion in the canopy.
The Association of HOTAIR with the Diagnosis and Prognosis of Gastric Cancer and Its Effect on the Proliferation of Gastric Cancer Cells

Background Long noncoding RNAs (lncRNAs) are a group of noncoding RNA with the length of more than 200nt. They have been identified as important diagnostic and prognostic molecules for many cancers and play an important role in the development of cancers. However, their clinical value and roles in gastric cancer (GC) remain unclear. Methods The expression levels of HOTAIR in 54 GC tissues and their matched adjacent nontumor tissues from GC patients and 24 normal mucosa or those with minimal gastritis as healthy controls were determined by qRT-PCR. The expression levels of HOTAIR in human GC cell lines and a normal gastric epithelium cell line were also assessed by qRT-PCR. The potential relationships between its level in GC tissues and the clinicopathological features were analyzed. Furthermore, a receiver operating characteristic (ROC) curve was constructed. Additionally, the correlation between this lncRNA and overall survival (OS) was analyzed. SiRNA transfection was used to silence the expression of HOTAIR in GC cells. And cell proliferation and cell cycle assays were employed to determine the effect of HOTAIR on GC cell growth. Western blot was performed for the detection of the P53, P21, and Bcl2 proteins. Results The expression levels of HOTAIR were significantly upregulated in GC tissues and cell lines. Increased HOTAIR was associated with tumor differentiation, lymph node and distant metastasis, and clinical stage. Furthermore, the area under the ROC curve (AUC) was up to 0.8416 (95 % CI=0.7661 to 0.9170, P<0.0001). The sensitivity and specificity were 66.67 and 87.04%, respectively. The correlation between HOTAIR expression and overall survival (OS) was statistically significant. The hazard ratio was 2.681, and 95% CI of ratio was 1.370 to 5.248. In addition, knockdown of HOTAIR can inhibit GC cell growth and affect cell cycle distribution. And knockdown of HOTAIR could enhance the protein levels of P21 and P53. Conclusion The present study demonstrated that HOTAIR was highly expressed in GC tissues and may serve as a potential diagnostic and prognostic biomarker for GC. And HOTAIR promoted GC cell proliferation.
Original Article : Therapeutic Effects of Growth Factor Cocktail Treatment in Patients with Androgenetic Alopecia According to the Depth of Microneedle

Background: Growth factor treatment in combination with microneedling in androgenetic alopecia (AGA) patients is safe and effective. However, there is a lack of studies examining the effect of treatment according to the depth of the microneedle. Objective: The aim was to evaluate differences in efficacy according to the depth of microneedle. Methods: This study was performed on 6 male and 5 female AGA patients who were treated with topical growth factor cocktail (GFC) with microneedling every 2 weeks for 3 months. The scalp was divided into right and left sides and treated with microneedle depths of 0.5 and 0.3 mm, respectively. GFC was topically applied using a microneedle medical device. Treatment efficacy was evaluated by phototrichogram and digital photograph analysis on 6 repeated treatments for 3 months. Results: Phototrichogram of the 0.5- and 0.3-mm-treated sides of the scalp showed 19 and 12 cm2 increase in hair density and 2.6- and 1.8-μm increase in hair diameter, respectively. These results were statistically significant (p＜ 0.05). In terms of density, the 0.5-mm depth was significantly more effective than the 0.3-mm depth (p＜0.05). With regard to diameter, the effect according to microneedle depth was not significantly different (p＞0.05). Conclusion: GFC treatment with microneedling is effective and safe and a microneedle depth of 0.5 mm appears to be more effective than that of 0.3 mm. More research is necessary to confirm these results and determine the most effective depth for microneedling by investigating various depths. (Korean J Dermatol 2016;54(3):184~189)
A NORTH INDIAN SKULL BASED STUDY OF A MORPHOLOGICAL AND MORPHOMETRICAL MEASUREMENTS OF FORAMEN MAGNUM.

Foramen magnum is a Latin word meaning largest aperture in skull. It is formed by the fusion of the four individual parts of the occipital bone (pars squama, left and right pars lateralis, and pars basilaris). The major structures passing through this foramen are the lower end of the medulla oblongata, meninges, vertebral arteries and the spinal accessory nerve.Present study conducted in the Department of Anatomy, Saraswati medical college. Study conducted on completely ossified adults 92 dry skulls. Deformed and fractured skulls were excluded from the study.Anteroposterior diameters (Anteroposterior diameter of foramen magnum is the distance measured between Basion and opisthion.). Transverse diameters (Transverse diameter of foramen magnum is the distance measured at right angles to anteroposterior diameter of foramen magnum). Area of the foramen magnum-anteroposterior diameters / transverse diameter.In our study the mean anteroposterior diameter was 34.46 ± 2.42. The mean measurement of transverse diameter was 29.23 ± 2.1. The mean surface area of foramen magnumwas 789 ±91.01. When the index of foramen magnum was > 1.2, the foramen was considered to be ovoid.In the present study we found 63.05% skulls exhibited ovoid shape foramen magnum.The incidence of themorphological types of foramen magnum hadthe following frequency of distribution: Oval 56(60.87%),Round 4(4.35%), Egg 13(14.13%), Tetragonal 15(16.30%),Pentagonal 4(4.35%). The morphometry of foramen magnum is necessary for surgeon during the surgeries of foramen magnum meningiomas or posterior cranial fossa lesions and also in determining Arnold Chiari Syndrome.
Mott variable-range hopping transport in a MoS2 nanoflake

The transport characteristics of a disordered, multilayered MoS2 nanoflake in the insulator regime are studied by electrical and magnetotransport measurements. The MoS2 nanoflake is exfoliated from a bulk MoS2 crystal and the conductance G and magnetoresistance are measured in a four-probe setup over a wide range of temperatures. At high temperatures, we observe that ln G exhibits a −T−1 temperature dependence and the transport in the nanoflake dominantly arises from thermal activation. At low temperatures, where the transport in the nanoflake dominantly takes place via variable-range hopping (VRH) processes, we observe that ln G exhibits a −T−1/3 temperature dependence, an evidence for the two-dimensional (2D) Mott VRH transport. Furthermore, we observe that the measured low-field magnetoresistance of the nanoflake in the insulator regime exhibits a quadratic magnetic field dependence ∼ αB2 with α ∼ T−1, fully consistent with the 2D Mott VRH transport in the nanoflake.
Role of the proinflammatory environment in the immunogenicity of therapeutic factor viii in patients with severe hemophilia A

Hemophilia A is a rare X-linked hemorrhagic disease consecutive to the lack of functional pro-coagulant factor VIII (FVIII). In patients with the severe form of hemophilia A, uncontrolled hemorrhages increase the morbidity and affect the quality of life. To prevent or treat bleeding episodes, therapeutic FVIII is administered intravenously. However, an anti-FVIII immune response develops in 5 to 30% of the patients. The anti-FVIII immune response is characterized by the development of anti-FVIII IgG antibodies that inhibit FVIII activity. These antibodies, referred to as “FVIII inhibitors” represent the major complication in the treatment of hemophilia A patients. Several risk factors have been suggested or proposed to predispose to the development of FVIII inhibitors. Amongst them, inspired by the “danger” theory, the presence of inflammatory mediators released upon bleeding episodes is thought to adjuvant the anti-FVIII immune response. Bleeding episodes trigger several pro and anti-inflammatory mechanisms. Thus, damage to the endothelium triggers the recruitment and activation of effector cells from the innate and adaptive compartments of the immune system. During my PhD, I investigated the role of bleedings in the development of the anti-FVIII immune response. Thus, I discovered an association between a polymorphism in the promoter region of a gene that is induced in response to bleedings, and the presence of FVIII inhibitors in a cohort of patients with severe hemophilia A. I followed the development of the immune response to therapeutic FVIII in a mouse model that mimics the localized bleedings found in patients with severe hemophilia A. Ultimately, I characterized the effects of reactive oxygen species (ROS) that are potentially released at the bleeding site in view of the structure, function and immunogenicity of the FVIII molecule. The results I obtained during my PhD demonstrate that bleedings are not associated with a higher risk for FVIII inhibitor development in the commonly used mouse model of severe FVIII deficiency. Additionally, I demonstrated an association between a polymorphism in the promoter of the HMOX1 gene and the presence of FVIII inhibitors. In parallel, I report for the first time an exacerbated oxidative status in FVIII-deficient mice as compared to control mice, and demonstrate that the control of the oxidative status in vivo reduces the anti-FVIII immune response. Conversely, the exposure of FVIII to ROS ex vivo increases the immunogenicity of the FVIII molecule. Taken together, my results suggest that, although the pro-inflammatory molecules released upon bleeding may positively affect the anti-FVIII immune response, several strong anti-inflammatory compounds are generated in vivo that dampen the potential adjuvant effect of bleedings. Ultimately, these results highlight the complex balance between the pro and anti-inflammatory mediators generated upon bleeding and their effect on the anti-FVIII immune response.