Miracle-dz/UniFAR-FTUs huggingface dataset:
Single-Dose Amoxicillin Therapy for Urinary Tract Infection-Reply

In Reply. — We appreciate Dr Rubinoff's comments and would agree with the thrust of his argument—that is, single-dose therapy can and should be given to reliable women with acute, uncomplicated UTI without having to resort to the antibody-coated bacteria (ACB) assay. Our using the ACB assay for research purposes does not constitute a requirement that it be used in everyday clinical practice. To put the ACB test and single-dose therapy in perspective, we would make the following comments: Single-dose therapy is effective in 85% to 95% of women with ACB-negative infection, with most of these failures occurring in women with first infections for which the ACB test is unreliable. Single-dose therapy is effective in 40% to 50% of patients with ACB-positive infection (R. H. Rubin, MD, unpublished data, October to December, 1980), confirming Dr Rubinoff's observation. Thus, the ACB-positive population is nonhomogeneous, and the response to single-dose
Endoscopy and Colonoscopy in a Situs Inversus Totalis Patient: A Case Report

Situs inversus totalis (SIT) is a very rare autosomal recessive condition that occurs in 1 out of 8,00020,000 people. Many endoscopic and colonoscopic procedures are performed in SIT patients, and they are difficult due to a complete left-right reversal of the internal organs. However, a throughout review of the endoscopic and colonoscopic procedures in such patients has never been conducted. A previous appendectomy and a large uterine myoma may make a colonoscopic procedure more difficult due to the adhesion and external compression. We performed endoscopy and colonoscopy without pain or complication in a SIT patient who had undergone appendectomy and had a large uterine myoma. We attribute this good result to careful preparation and sticking to the general principles of colonoscopic procedures.
The Effects of Semantic Neighborhood Density on the Processing of Ambiguous Words

Semantic neighborhood density’s effects on the processing of ambiguous words were examined in three lexical decision experiments. Semantic neighborhoods were defined in terms of semantic set size and connectivity in Experiment 1, and in terms of semantic set size in Experiments 2 and 3. In Experiment 1, set size, connectivity, and ambiguity were crossed. An ambiguity disadvantage was observed for large set, high connectivity words, and there was some suggestion of an ambiguity advantage for small set, high connectivity words. Experiments 2 and 3 held connectivity constant at a high level, and set size and ambiguity were crossed, with Experiment 3 using pseudohomophone nonwords. Neither experiment produced an ambiguity advantage. Participants responded faster to unambiguous words relative to ambiguous words, particularly for large set size words, essentially supporting Experiment 1’s results. These results are discussed within a framework in which meaning-level competition can affect the recognition of semantically ambiguous words.
Contrast from a Contrastive Perspective

The cageless thrust bearing with unguided cylindrical rollers comprises a pair of thrust bearing races with axially separated flat thrust raceways. Cylindrical rollers all having the same diameter are located between the separated flat thrust raceways. The spacing of the rollers is such that the rollers become radially aligned in the bearing under a rotating thrust load, without side or end guidance of the rollers.
Surgical Pathology of the Nervous System and its Coverings

Advances and Technical Standards in Neurosurgery Vol 2 By H. Krayenbuhl. Pp. 217; illustrated; $3.30. ) Springer: Wein. 1975. This is the second of a series of publications edited by a group of distinguished European neurosurgeons. The object of the series is an attempt to overcome the lack of any organised common European postgraduate training system for young neurosurgeons and to make use of the English language as a means of communication of scientific information between Europeans. The second volume, like the first, admirably fulfils these ambitions. The first section on 'Advances' considers in very adequate detail three important topics. Computerised axial tomography with the EMI-scanner is dealt with in a concise but comprehensive fashion by the group at the National Hospital, Queen Square, who have been associated with this technique from the start. Professor Sanmii of the University of Mainz gives
Solving a generalised precedence multi-objective multi-mode time-cost-quality trade-off project scheduling problem using a modified NSGA-II algorithm

In this paper, a new mathematical formulation is proposed to model a generalised precedence multi-objective multi-mode time-cost-quality trade-off project scheduling problem (GPDTCQTP). Afterwards, a modified NSGA-II algorithm is developed to solve the proposed GPDTCQTP. The modified NSGA-II utilises a dynamic parameter tuning and a heuristic self-adaptive constraint handling strategy. These properties result in proper performance in regenerating the Pareto front of the GPDTCQTP. Investigating the efficiency of proposed algorithm several benchmark instances are systematically generated and solved. The proposed procedure is straightforward and results are promising.
The dialogical bricoleur? Expectations towards internet-based services in Norway and Sweden

Mental health is a multifaceted concept that has been described and understood differently throughout history. The emergence of internet-based services has signalled changes in both the delivery of services and the understanding of mental health that could alter expectations towards professionals. This study explores the implicit images of answerers online culled from messages by individuals who use internet-based mental health services (henceforth, submitters) and discusses the possible implications of the answerers. An internet search identified Norwegian and Swedish websites, and 444 messages from 13 of those services were included in our study and analysed via qualitative content analysis. Ten images of the answerers were constructed in this process and they were gathered into four main images named ‘the specialist’, ‘the counsellor’, ‘the therapist’ and ‘the master of discourse’. These four images form the structural element in our presentation of the empirical interpretations and serve as the main expectations towards the services. This article discusses these empirical interpretations in the context of both the scientific ‘bricoleur’ and the Open Dialogue Approach. Our results suggest that the ‘dialogical bricoleur’ is a unifying image in submitters’ expectations towards answerers online. Our study argues for strengthening sensitivity towards submitters and increasing the capacity to encompass human variation on the internet.
Learning to do, learning to be: the transition to competence in critical care nursing

vii Chapter One: Introduction 2 Section One Chapter Two: Background and Literature Review 10 Chapter Three: Research Methodology and Methods 23 Section Two Chapter Four: Learning Under Pressure – Influences on the Learner 40 Chapter Five: Learning to do; Learning to be 55 Section Three Chapter Six: Discussion and Recommendations 72 References 87 Appendix One: Ethics Committee Approval 93 Appendix Two: Advertisement for Professional Bulletin 94 Appendix Three: Participant Information Sheet 95
Imaging of Vx‐2 rabbit tumors with ανβ3‐integrin‐targeted 111In nanoparticles

Earlier tumor detection can improve 5‐year survival of patients, particularly among those presenting with cancers less than 1 cm in diameter. ανβ3‐Targeted 111In nanoparticles (NP) were developed and studied for detection of tumor angiogenesis. Studies were conducted in New Zealand white rabbits implanted 12 days earlier with Vx‐2 tumor. ανβ3‐Targeted 111In/NP bearing ∼10 111In/NP vs. ∼1 111In/NP nuclide payloads were compared to nontargeted radiolabeled control particles. In vivo competitive binding studies were used to assess ligand‐targeting specificity. ανβ3‐Integrin‐targeted NP with ∼10 111In/NP provided better (p < 0.05) tumor‐to‐muscle ratio contrast (6.3 ± 0.2) than ∼1 111In/NP (5.1 ± 0.1) or nontargeted particles with ∼10 111In/NP (3.7 ± 0.1) over the initial 2‐hr postinjection. At 18 hr, mean tumor activity in rabbits receiving ανβ3‐integrin‐targeted NP was 4‐fold higher than the nontargeted control. Specificity of the NP for the tumor neovasculature was supported by in vivo competition studies and by fluorescence microscopy of ανβ3‐targeted fluorescent‐labeled NP. Biodistribution studies revealed that the primary clearance organ in rabbits as a %ID/g tissue was the spleen. Circulatory half‐life (t1/2β) was estimated to be ∼5 hr using a 2‐compartment model. ανβ3‐Targeted 111In perfluorocarbon NP may provide a clinically useful tool for sensitively detecting angiogenesis in nascent tumors, particularly in combination with secondary high‐resolution imaging modalities, such as MRI. © 2007 Wiley‐Liss, Inc.
Model Ideal Manajemen Teknologi Informasi dan Komunikasi dalam Mendukung Operasional Penanganan Bencana Alam

Model ideal manajemen TIK dalam operasional penanggulangan bencana mensyaratkan adanya penambahan Bagian Urusan Teknologi dalam struktur Badan Penanggulangan Bencana Daerah (BPBD). Bagian ini nantinya akan memiliki dua seksi, yakni Seksi Operasional Administrasi dan Seksi Operasional Lapangan. Penelitian ini bermaksud untuk membuktikan efektivitas model tersebut melalui pendekatan deskriptif kualitatif. Hasil penelitian menunjukkan bahwa model pengelolaan TIK yang menambahkan bidang TIK pada struktur BPBD terbukti memiliki kehandalan pada masa aman, masa bencana dan masa pascabencana. Kata Kunci : Manajemen, Teknologi Komunikasi Informasi, Kehandalan model
Effect of administering kefir on the changes in fecal microbiota and symptoms of inflammatory bowel disease: A randomized controlled trial.

BACKGROUND/AIMS Kefir is a kind of fermented probiotic dairy product. The objective of the present study was to investigate the effects of kefir consumption on the fecal microflora and symptoms of patients with inflammatory bowel disease (IBD). MATERIALS AND METHODS Kefir was serially diluted and inoculated into de Man, Rogosa, and Sharpe agar and incubated at 37°C for 48 to 72 h under anaerobic conditions. This was a single-center, prospective, open-label randomized controlled trial. Forty-five patients with IBD were classified into two groups: 25 for treatment and 20 for control. A 400 mL/day kefir was administered to the patients for 4 weeks day and night. Their stool Lactobacillus, Lactobacillus kefiri, content was quantitated by real-time quantitative polymerase chain reaction before and after consumption. Abdominal pain, bloating, stool frequency, stool consistency, and feeling good scores were recorded in diaries daily by the patients. RESULTS A 5×107 CFU/mL count of lactic acid bacteria colony forming units was found in a kefir sample as the total average count. Lactobacillus bacterial load of feces of all subjects in the treatment group was between 104 and 109 CFU/g, and the first and last measurements were statistically significant (p=0.001 in ulcerative colitis and p=0.005 in Crohn's disease (CD)). The L. kefiri bacterial load in the stool of 17 subjects was measured as between 104 and 106 CFU/g. For patients with CD, there was a significant decrease in erythrocyte sedimentation rate and C-reactive protein, whereas hemoglobin increased, and for the last 2 weeks, bloating scores were significantly reduced (p=0.012), and feeling good scores increased (p=0.032). CONCLUSION According to our data, kefir consumption may modulate gut microbiota, and regular consumption of kefir may improve the patient's quality of life in the short term.
Supporting Digital Transformation in Small and Medium-sized Enterprises: A Procedure Model Involving Publicly Funded Support Units

Digital Transformation (DT) considers the continuous digitalization process of a company, which uses digital and data-driven innovation to improve existing processes, change distinct business model (BM) elements, or reinvent its BM entirely. Large companies position themselves at the frontline of the DT, while small and medium-sized enterprises (SMEs) are challenged by resource constraints and missing guidance on realizing benefits of DT. This situation threatens SMEs as big players increasingly utilize DT to enter markets that have been traditionally reserved to SMEs. Extant research on the ways SMEs can effectively participate in DT is limited. Against this background, this article builds upon prior research and a focus group discussion to propose a procedure model, which enables DT in SME by involving publicly funded support units. These units help SMEs in understanding and structuring the potentials of digital and data-driven innovation.
Moral Judgment as a Predictor of Clinical Performance

laving li~pot1iesi:etl a rlirc~shvltl evel ? / . toral reasoning as a necessary cwritlitiori 3r atleyirare. pli! rician perfvrtiratrce. 1 1 ~ ' 'ai'e studied 244 pediatric liuiae oJficers ver f l i t past,futir jeors. Using h'vh/herg'. s ~anilardi:eiI interviews and Rest's Deiring Issires Test as tireasiires v fnwralr i~amitrg. antl,faculty ratings a5 tiieasiires v/ linical per/Orniatii.e. the Clara shvn. a cvn4tent and nieamingfirl relotivruliip heweti tiieasiircs o/ nroral rra~vtiiiig arid irings uf clitiiid perfvrtiianw.
Efficacy and safety of BI 671800, an oral CRTH2 antagonist, as add on therapy in poorly controlled asthma patients prescribed an inhaled corticosteroid

Background BI 671800 is an antagonist of the PGD2 receptor, CRTH2. PGD2 stimulates bronchoconstriction and allergic airway inflammation in animal models. Inhibition of CRTH2 may reduce airway inflammatory cells, IL -4, -5, -13 production, serum IgE and airway hyper reactivity. Objective To investigate the efficacy and safety of BI 671800 versus placebo and montelukast in poorly controlled asthma patients as add on therapy to fluticasone propionate (FP) MDI (88 μg, bid). Methods Adults with asthma (FEV1 60-85% and ACQ >= 1.5) were enrolled in a randomized, double-blind, parallel arm study comparing BI 671800 400 mg bid with matching placebo bid or montelukast 10 mg qd for six weeks. The primary study outcome was change in trough FEV1. Results 243 patients were randomised (mean age 41.6 years, FEV1 72%, ACQ 2.1). Change from baseline in adjusted mean (SE) trough morning FEV1% predicted versus placebo was 3.87% (1.49) for BI 671800 and 2.37% (1.57) for montelukast, (one sided p < 0.025 for BI 671800), achieving the primary efficacy outcome for the study. Change in ACQ mean (SE) scores versus placebo were -0.28 (0.12) and -0.18 (0.12) for BI 671800 and montelukast respectively (one sided p < 0.025 for BI 671800). No significant imbalance in adverse events, or differences in vital signs or laboratory assessments were observed. Conclusion Treatment with BI 671800 in poorly controlled asthmatic patients receiving FP was associated with a significant improvement in FEV1. BI 671800 was well tolerated at a total daily dose of 800 mg for 6 weeks.
Effectiveness of treatment prescribed by GPs: patient assessment

Aim We investigated patients’ impressions of the effectiveness of treatment provided by health centre physicians. Were the patients’ expectations met, and were the consultations considered effective? Which factors affected consultation success? Background The study was conducted in 16 municipalities in the Kanta-Häme region Finland in 2004. Primary healthcare services to these municipalities are provided by five health centres. The municipalities’ total population was 166 648 (31 December 2003). Methods The data were collected during telephone interviews, supplemented by a mail survey. The study population (2600) was drawn from the Finnish Population Information System by random sampling. A total of 1751 inhabitants participated in the study (response rate: 67%). The respondents were considered able to evaluate treatment effectiveness if they had visited a health centre physician because of an illness or an accident during the past 12 months. Seven hundred and twenty-nine respondents met these criteria. Findings Most respondents (73%) found that their treatment corresponded with their expectations. According to a logistic regression analysis, the factors that best explained whether the patient’s treatment expectations were met included the physician’s respect for the patient, the consultation duration and the reason for the visit. Of the respondents, 70% thought the consultation had been effective. Factors explaining consultation effectiveness included consultation duration, physician’s respect for the patient and whether the consultation was scheduled within three days. In conclusion, the physician–patient consultations seemed to be very good and clearly worth the effort. Notably, we observed that the same factors helped to explain whether the patient’s treatment expectations were met, and whether the patient found the consultation effective.
Clinico-Epidemiological Study Of Factors Associated With Pregnancy Induced Hypertension

Research Question: What are the factors responsible for pregnancy induced hypertension. Objectives: To determine whether maternal, demographic, clinical and socio-economic characteristics are predictive of hypertension associated with pregnancy. Study design: Cross â€“ Sectional. Participants: 728 hypertensive pregnant mothers attending the ante-natal clinic and admitted to the inpatient department of obstetric unit. Study Variables: Maternal, demographic and socio-economic characteristics. Outcome variable: Hypertension associated with pregnancy. Statistical analysis: Percentages and proportions. Results: The relative incidence of pregnancy induced hypertension was 71.29%. The critical evaluation of social and demographic characteristics of 519 cases of pregnancy induced hypertension revealed that nulliparous, young women (15-25 years) belonging to low socio-economic group with lower literacy status and higher house hold work load are more vulnerable to develop pregnancy induced hypertension. Inadequate diet having low protein, rich carbohydrate and extra salt intake played a crucial role in the development of pregnancy induced hypertension. Conclusions: i) since the nulliparous and younger women are vulnerable to develop pregnancy induced hypertension, the age at first pregnancy be reasonably delayed. ii) Balanced diet is to be ensured through appropriate nutrition education and within t he resources of the family. iii) The heavy household work is to be avoided and adequate rest and sleep be ensured in those who are at risk of developing pregnancy induced hypertension.
Knowledge and knowers in online learning: Investigating the effects of online flexible learning on student sojourners

iii List of Figures x List of Tables xi Chapter 1 – Introduction 1 1. 1 Background to the study 1 1.1.1 Online flexible learning in Australian higher education 1 1.1. 2 Chinese international students in Australian higher education 4 1. 2 The research problem 5 1. 3 Aim of the study and research strategy 5 1. 4 Significance of the study 8 1. 5 Overview of the thesis 9 Chapter 2 – Literature Review 10 2.
An improved cortex-like neuromorphic system for target recognitions

This paper reports on the enhancement of biologically-inspired machine vision through a rotation invariance mechanism. Research over the years has suggested that rotation invariance is one of the fundamental generic elements of object constancy, a known generic visual ability of the human brain. Cortex-like vision unlike conventional pixel based machine vision is achieved by mimicking neuromorphic mechanisms of the primates' brain. In this preliminary study, rotation invariance is implemented through histograms from Gabor features of an object. The performance of rotation invariance in the neuromorphic algorithm is assessed by the classification accuracies of a test data set which consists of image objects in five different orientations. It is found that a much more consistent classification result over these five different oriented data sets has been achieved by the integrated rotation invariance neuromorphic algorithm compared to the one without. In addition, the issue of varying aspect ratios of input images to these models is also addressed, in an attempt to create a robust algorithm against a wider variability of input data. The extension of the present achievement is to improve the recognition accuracies while incorporating it to a series of different real-world scenarios which would challenge the approach accordingly.
Chronic thromboembolic pulmonary vascular disease: physiological concepts and genetic predisposition

s derived from this work C McCabe, S Hoole, P White, R Axell, L Shapiro, J Pepke-Zaba. Inefficient right ventriculo-arterial coupling contributes to reduced exercise capacity in pulmonary hypertension. Oral presentation: BTS Winter Meeting 2013 C McCabe, S Graf, K Sheares, J Pepke-Zaba, N Morrell. Whole exome sequencing identifies novel genetic variation in chronic thromboembolic pulmonary hypertension. Oral presentation: BTS Winter Meeting 2012 O Davies, C McCabe, J Pepke-Zaba, K Sheares. High dose oestrogens commenced for gender reassignment surgery may predispose to the development of chronic thromboembolic pulmonary vascular disease. Oral presentation: BTS Winter Meeting 2013
Infinitives: Restructuring and Clause Structure

Infinitives: Restructuring and Clause Structure offers a detailed study of the clausal architecture of infinitival constructions providing a unified analysis of restructuring, control, modals, and raising. The book critically evaluates previous proposals from both syntactic and semantic perspectives and presents a new analysis incorporating many recent developments in generative linguistic theory. In addition to its theoretical contribution, Infinitives contains a detailed descriptive overview of a range of constructions, primarily from the Germanic languages and will thus not only be of value to generative linguists but will also serve as a general reference source for those interested in the Germanic languages.
The apple and the talking snake : feminist dream readings and the subjunctive curriculum

In this dissertation I develop a theoretical framework for the practice of dream reading as a form of literary engagement worthy of attention from educators. Dream reading is a form of research in which the researcher takes responsibility for selfreflection and potential transformation of self through the construction of knowledge based on “reading” literary fictive images as if they arose from night dreams. This study develops dream reading theory through an exploration of Carol Shields’ novel, Unless, as if it were a dream. It examines women’s silence and the disposition of fear of knowing from multiple perspectives. The study uses my personal dream journals together with a variety of theoretical works in feminist, consciousness and dream theories to inform interpretations of Norah, Reta, Lois, and Danielle. For as Donald (2001) says, “when stories and ideas are juxtaposed, so that their meanings collide, they can shift our focus to new semantic spaces [to] clarify the experienced world” (p. 294). This work is a limit case that investigates women’s silence and fear of knowing as they emerge from my personal experience of resistance to the chaos and uncertainty of disintegrating and rebuilding through midlife into crone. The study shows how dream reading a literary text might gather together and rearrange lived experience and encourage the creation and re-creation of life stories from different perspectives. Dream reading contributes to the study of the details of the phenomenology of inside/outside cognitive worlds. Exploring literary fiction and personal dreams suggests that literary fiction read as if it were a dream can contribute to the identification of shifting self-knowledge and the creation of new myths subversive to the patriarchal Symbolic Order. Narrating and re-creating reader-response experience