Miracle-dz/UniFAR-FTUs huggingface dataset:
Cellular information in the genome of recovered avian sarcoma virus directs the synthesis of transforming protein.

Recovered avian sarcoma viruses, whose sarcomagenic information is largely derived from cellular sequences [Wang, L. -H. , Halpern, C.C. , Nadel, M. & Hanafusa, H. (1978) Proc. Natl. Acad. Sci. USA 75, 5812-5816], produce the transforming protein p60src in infected cells, in amounts comparable to the amount found in cells transformed by standard strains of avian sarcoma virus. Though displaying some virus-specific differences in electrophoretic mobility, p60srcs from these viruses are similar to those of other avian sarcoma virus strains by the criteria of (i) antigenicity, (ii) partial proteolysis mapping, and (iii) association with protein kinase activity. We also find that p60sarc, a protein present in normal cells at a low level, is associated with a protein kinase activity, and thus it too is similar by the above criteria to p60src of avian sarcoma virus. Possible causes for the pathogenicity of p60src are discussed in light of these similarities.
Antecedents and consequences of trust and satisfaction in buyer‐seller relationships

The perspective of marketing has changed from regarding marketing as a series of independent transactions to a dynamic process of establishing, maintaining and enhancing relationships. In an emerging theory of relationship marketing, both trust and satisfaction are core concepts in understanding the dynamics of how relationships evolve. Although the literature has thoroughly examined both trust and satisfaction, the interrelationship between them, including their consequences and antecedents, has not yet been addressed properly. We propose that the development of buyer‐seller relationships can be understood as a sequence of decisions buyers make regarding whether they should enter a relationship, continue a relationship, or enhance the scope of a relationship. These are different kinds of decisions where satisfaction and trust are likely to play different roles in risk reductions depending on the nature of the decision to be made. In a study of institutional buyers of a food producer we find that satisfaction and trust are complementary in the sense that trust is a key variable when decisions are related to enhancement in scope of the relationship, whereas satisfaction is a key variable when the issue is relationship continuity.
A comparison of the Truview® blade with the Macintosh blade in adult patients

The Truview® blade facilitates a view of the vocal cords by indirect laryngoscopy. We prospectively compared the view obtained at laryngoscopy and intubating conditions of Truview (Group 1) or Macintosh (Group 2) blades in 170 patients who were scheduled to undergo general anaesthesia. We studied pre‐operative airway evaluation, laryngoscopic view, duration of intubation, maximal force applied during intubation, anaesthetist's estimation of intubation effort on a 1–3 scale, bleeding, teeth and soft tissue damage, and postoperative stridor and hoarseness. The results demonstrated that, whilst the Truview produced a better laryngoscopic view and less maximal force applied during intubation, the duration of intubation was longer. No significant difference was found in the anaesthetist's estimation of intubation effort, tooth damage or postoperative stridor and hoarseness. Significantly fewer patients suffered bleeding and soft tissue damage following intubation with the Truview than with the Macintosh blade. The Truview blade is a useful option for tracheal intubation in patients with normal and anticipated difficult airways.
The ICT adoption in enterprises in the context of the sustainable information society

This study, part of an ongoing global study, aims to advance information society research and practice by examining and understanding the information and communication technologies (ICT) adoption in enterprises in the context of the sustainable information society (SIS). In this study, the ICT adoption is described by four components. i.e. outlay on ICT, information culture, ICT management, and ICT quality, whereas the sustainability is composed of ecological, economic, socio-cultural, and political sustainability. This study employs a quantitative approach to identify the levels of ICT adoption and sustainability in enterprises as well as investigate the correlation between these two constructs. The survey questionnaire was used and data collected from 394 enterprises were analyzed. The research findings reveal that there were significant statistical differences between the highest level of outlay on ICT and the lowest ones, namely the levels of ICT quality and ICT management. Moreover, the economic sustainability was at the highest level, whereas the lowest and similar levels were specific to ecological and political sustainability. Finally, it is investigated that the ICT quality, ICT management, and information culture have a significant impact on the sustainability, whereas the outlay on ICT does not have such an impact. This study advances the information society research and practice by measuring the ICT adoption, sustainability and correlation between them in the Polish enterprises.
Purchasing and supply management: Future directions and trends

IN BRIEF This article provides a summary of The Purchasing Futures Research Project, sponsored by the Center for Advanced Purchasing Studies (CAPS). The project's goal was to develop a vision of the nature of the purchasing and supply management function in the next century, including roles, responsibilities, capabilities, and organizational structures. The article identifies various purchasing and business market trends and synthesizes these into strategic organizational propositions that describe how purchasing and supply management can develop during the next century.
Monetary Policy and Financial Asset Prices in Poland

The aim of this study is to investigate the effects of monetary policy on financial asset prices in Poland. Following Gurkaynak et al. (2005) I test how many factors adequately explain the variability of short-term interest rates around MPC meetings, finding that there are two such factors. The first one has a structural interpretation as a “current interest rate change” factor and the second one as a “future interest rate changes” factor, with the latter related to MPC communication. Regression analysis shows that, controlling for foreign interest rates and global risk aversion, both MPC actions and communication matter for government bond yields, and that communication is more important for stock prices. Furthermore, the foreign exchange rate used to depreciate (appreciate) after MPC statements signalling tighter (easier) future monetary policy. However, the effect disappeared at the end of the sample. For most of the sample the exchange rate would appreciate (depreciate) or would not change in a statistically significant manner after an increase (a decrease) of the current interest rate. The results indicate that not only changes of the current interest rate but also MPC communication matters for financial asset prices in Poland. It has important implications for the conduct of monetary policy, especially in a low inflation and low interest rate environment.
A Novel Single-RF Outphasing MIMO Architecture

A novel single-RF multiple-input multiple-output transmitter architecture based on the outphasing principle is presented. An efficient switching amplifier feeds a tunable analogue network with the unmodulated carrier. The carrier is then modulated utilising the outphasing principle and distributed to the antennas. Featuring only a small set of standard RF components - namely power splitters, phase shifters, and hybrid couplers - the structure can be readily implemented in a costefficient, passive integration manner. Various modulation schemes for the architecture are investigated including the particular power efficient phase shift keying on the hypersphere. Our numerical results show that the proposed architecture is a power- and cost-efficient solution for multi-antenna transmitters on energy-limited user devices.
Inhalation of the reactive aldehyde acrolein promotes antigen sensitization to ovalbumin and enhances neutrophilic inflammation

Abstract Acrolein (ACR), an α,β-unsaturated aldehyde and a major component of tobacco smoke, is a highly reactive electrophilic respiratory irritant implicated in asthma pathogenesis and severity. However, few studies have directly investigated the influence of ACR exposure on allergen sensitization and pulmonary inflammation. The present study was designed to examine the impact of ACR inhalation on allergic sensitization to the inhaled antigen ovalbumin (OVA), as well as pulmonary inflammation during subsequent OVA challenge. Adult male C57BL/6 mice were exposed to inhaled OVA (1%, 30 min/day, 4 days/week) and/or ACR (5 ppm, 4 h/day, 4 days/week) over 2 weeks and subsequently challenged with aerosolized OVA (1%, 30 min/day) over three consecutive days. Serum anti-OVA IgG1 levels were increased significantly in animals exposed to both OVA and ACR, compared to animals exposed to either OVA or ACR alone. In addition, differential cell counts and histological analysis revealed an increase in BAL neutrophils in animals exposed to both OVA and ACR. However, exposure to both OVA and ACR did not influence mRNA expression of the cytokines il5, il10, il13 or tnfa, but significantly increased mRNA expression of ccl20. Moreover, ACR exposure enhanced lung mRNA levels of il17f and tgfb1, suggesting development of enhanced inhalation tolerance to OVA. Overall, the findings indicate that ACR inhalation can promote airway-mediated sensitization to otherwise innocuous inhaled antigens, such as OVA, but also enhances immune tolerance, thereby favoring neutrophilic airway inflammation.
The role of ex vivo lung perfusion in lung transplantation

Whilst lung transplantation is a viable solution for end-stage lung disease, donor shortages, donor lung inflammation and perioperative lung injury remain major limitations. Ex vivo lung perfusion has emerged as the next frontier in lung transplantation to address and overcome these limitations, with multicentre clinical trials ongoing in the UK, rest of Europe and North America. Our research seeks to identify the poorly understood cellular and molecular mechanisms of primary graft dysfunction through the development of an isolated perfused lung model of transplantation and investigation of the role of pulmonary inflammation in this paradigm.
Tailored Meanings: On the Meaning and Impact of Organizational Dress

Dress in organizations is ubiquitous, yet it has been overlooked in organizational studies. Dress can reflect and create a variety of organizational dynamics. This article offers a framework to consider these dynamics. Three dimensions—attributes of dress, homogeneity of dress, and conspicuousness of dress—are identified. Relationships among these dimensions and organizational processes are proposed. Dress is argued to indicate internal and external processes. Dress also can affect individual and organizational outcomes, including employee compliance and legitimation and organizational image and utilization of human resources. A rich agenda for research is proposed.
COMPARISON OF SLAUGHTER YIELD AND CARCASS TISSUE COMPOSITION IN BROILER CHICKENS OF VARIOUS ORIGIN

Slaughter yield and carcass tissue composition were compared in three different broiler chicken production sets. The highest body weight (1892.5 g), eviscerated carcass weight with neck (1406.9 g) and slaughter yield (74.5%) were found in Ross 308 chickens, whilst the lowest values of these traits occurred in JV chickens (respectively: 1753.3; 1288.2 g; 73.3%). The highest muscle contents (45.4% breast muscles and leg muscles in carcass) and the lowest fattiness (7.9% skin with subcutaneous fat and 1.5% abdominal fat) were found in Hubbard Evolution chickens.
The Pricing of Long and Short Run Variance and Correlation Risk in Stock Returns

This paper studies the pricing of long and short run variance and correlation risk. The predictive power of the market variance risk premium for returns is driven by the correlation risk premium and the systematic part of individual variance premia. Furthermore, I find that aggregate volatility risk is priced in the cross-section because shocks to average stock volatility and correlation are priced. Both long and short run volatility and correlation factors have explanatory power for returns. Finally, I resolve the idiosyncratic volatility puzzle by showing that short-term idiosyncratic risk is positively priced whereas long-term idiosyncratic volatility carries a negative price.
Pediatric bipolar disorder: evidence-based psychopharmacological treatments.

TOPIC Pediatric bipolar disorder can cause severe disturbances in global functioning. Diagnosing pediatric bipolar disorder is challenging due to the range of symptom expression, developmental differences as compared to adults, presence of comorbid disorders, and developing diagnostic criteria. Treating this disorder can be equally challenging due to frequent symptom relapse and the dearth of research until recently on effective psychopharmacological interventions that guide clinical prescribing practices. PURPOSE This paper will help child psychiatric nurses have a better understanding of the unique presentation of pediatric bipolar disorder to facilitate selection of appropriate medication treatment options, taking into account symptom presentation, presence of comorbid diagnosis, drug efficacy, adverse effects, and drug-drug interactions based on research findings. SOURCES Literature specific to assessment and psychopharmacological treatment of pediatric bipolar disorder was reviewed. CONCLUSIONS Screening of youth with mood spectrum problems for bipolar disorder should occur in every diagnostic assessment and should be ongoing due to range of mood symptoms and the cyclical and episodic nature of this disorder. Youth with bipolar disorder may manifest symptoms and course that differ from adults. Additionally, co-occuring disorders are common in this population, which can complicate medication selection. Psychopharmacological treatment with the use of specific mood stabilizers and/or atypical antipsychotic medications is warranted depending on symptom presentation; however, monotherapy with mood stabilizers has not demonstrated effectiveness in long-term remission of pediatric bipolar symptoms. Recent research indicates that a combined treatment with two mood stabilizers or a mood stabilizer and an antipsychotic holds promising results for pediatric bipolar I, for youth with acute manic symptoms plus psychosis, and for long-term remission of symptoms.
Pharmacokinetics of Naratriptan in Adolescent Subjects with a History of Migraine

Naratriptan is a novel 5‐HT1 agonist developed to treat acute migraine. The study objective was to characterize the pharmacokinetics of oral naratriptan in adolescent migraine patients outside a migraine attack. Subjects received a single 2.5 mg naratriptan tablet. Serial serum samples for naratriptan concentrations were collected over 24 hours. Blood pressure, pulse rate, and 12‐lead ECG were recorded at baseline and at regular intervals after dosing. Seven patients—3 males and 4 females, 12 to 16 years of age—received drug and completed the study. The geometric mean and 95% confidence interval maximum concentration (Cmax) was 8.0 ng/mL (5.9–10.7), elimination half‐life (t1/2) was 4.9 hours (4.5‐5.4), area under the concentration‐time curve (AUC) was 74.6 ng•h/mL (56.6–98.2), and apparent total clearance (Cl/F) was 558.8 mL/min (424.3–735.9). The median time to maximal concentration (tmax) was 4 hours, with a range of 1.5 to 4. Blood pressure, pulse rate, and ECG parameters did not change significantly from baseline. No serious adverse events or subject withdrawal after drug administration occurred. Oral naratriptan pharmacokinetic parameters in adolescents were similar to values reported in adults. Naratriptan doses for adolescents older than 12 years of age would be expected to be similar to adult doses.
Design for Value Co-Creation: Exploring Synergies Between Design for Service and Service Logic

This paper aims to bridge recent work on Service Logic with practice and research in the Design for Service to explore whether and how human-centered collaborative design approaches could provide a source for interpreting existing service systems and proposing new ones and thus realize a Service Logic in organizations. A comparison is made of existing theoretical backgrounds and frameworks from Service Logic and Design for Service studies that conceptualize core concepts for value co-creation: actors, resources, resource integration, service systems, participation, context, and experience.We find that Service Logic provides a framework for understanding service systems in action by focusing on how actors integrate resources to co-create value for themselves and others, whereas Design for Service provides an approach and tools to explore current service systems as a context to imagine future service systems and how innovation may develop as a result of reconfigurations of resources and actors. Design for Service also provides approaches, competences, and tools that enable involved actors to participate in and be a part of the service system redesign. Design for value co-creation is presented using this model.The paper builds on and extends the Service Logic research first by repositioning service design from a phase of development to Design for Service as an approach to service innovation, centered on understanding and engaging with customers' own value-creating practices. Second, it builds on and extends through discussing the meaning of value co-creation and identifying and distinguishing collaborative approaches for the generation of new resource constellations. In doing so, the collaborative approaches allow for achieving value co-creation in designing.
Analysis by paralysis: the pension purchase decision process

Purpose – Attempts to understand the consumer behaviour in the context of the pension purchase process, including the decision process and factors affecting the decision.Design/methodology/approach – Focus groups were conducted among manual and clerical grades of employees within a public sector organization who were members of an occupational pension scheme.Findings – Despite the relative importance of pensions and the degree of risk associated with the purchase, the findings clearly indicate that purchasing decisions in this context are neither completely informed nor rational. The process described by focus group participants suggests “analysis by paralysis”, characterized by complexity, confusion and apathy.Research limitations/implications – Small number of focus groups and a focus on manual and clerical grades of employment only. A larger sample and representation of other grades of employment might yield differences in decision making between different segments of the population.Practical implicati.
Determinants of international retail operation mode choice: Towards a conceptual framework based on evidence from French specialised retail chains

Abstract More and more retailers have expanded internationally. Because of its impact on the success of a retailer's international operations, a critical aspect of an internationalisation strategy consists of choosing the appropriate entry and expansion modes. The phenomenon remains misunderstood as little research in international retailing has focused on this question and findings from international management literature find limited application to services. This paper draws upon a literature review and six case-studies from French specialised retailers to provide an exploratory framework for examining key determinants of operation mode choice. It is found that retailers consider four underlying dimensions of operation modes. These dimensions are affected by situational, individual and marketing factors whose explanatory impacts are moderated by the motives for internationalisation and relationship networks.
The Influence of the Country-of-Origin Image, Advertising Appeal, and Product Attitude on Purchase Intention: The Moderating Effects of Product Involvement

The main purpose of this study is to investigate the influence of Country-of-Origin image, advertising appeal, and product attitude on purchase intention, and the moderating effects of product involvement. Japan and Korea were selected as Countries-of-Origin, and the digital camera industry was taken as research objects. The television commercial was used in the experimental design to measure the respondent's purchasing intention for products from different countries. The convenience sampling method was used to collect primary data and the samples were chosen from consumers in the Taipei area. A total of 400 questionnaires were distributed, 360 effective questionnaires were collected, and the effective response rate was 90%. Regression analysis was used to test the hypotheses. The main findings were as follow: (1) The country-of-origin image has a significantly positive effect on product attitudes. (2) The technology from the country-of-origin has a significantly positive effect on product attitudes. (3) The image of the country-of-origin has a significantly positive effect on product attitudes. (4) Product attitudes have significantly positive effects on purchase intention. (5) Finally, The influence of product attitudes on consumers' purchase intention in low product involvement situations is greater than that in high product involvement situations.
The effects of fraudulent procurement practices on public procurement performance

With an increasing number of organisations using suppliers based in emerging economies, potential opportunities for fraud and corruption especially within the public procurement sphere are likely to escalate. Fraud involves the intent to deceive through false representation of a matter of fact, whether by word or by conduct, or by concealment of information, which should have been disclosed, in order to cause an entity rely or act upon that misleading or false information and ultimately causing damages to the entity relying upon that false information. With procurement fraud or fraudulent procurement, the misrepresentation of truth in most cases can occur at every stage within the procurement cycle or process. Although there has been a lot of research done on the subject of fraud and corruption in general, researches linking fraudulent and corrupt practices to the public procurement performance aspect are still meager. This concept paper sought to provide a concretized elaboration on these terminologies, and how they are likely to result into adverse public procurement performance outcomes, with the view of leading to an empirical study on the same