Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of dietary patterns on ambulatory blood pressure : results from the Dietary Approaches to Stop Hypertension (DASH) Trial. DASH Collaborative Research Group.

We measured ambulatory blood pressure (ABP) in 354 participants in the Dietary Approaches to Stop Hypertension (DASH) Trial to determine the effect of dietary treatment on ABP (24-hour, day and night) and to assess participants' acceptance of and compliance with the ABP monitoring (ABPM) technique. After a 3-week run-in period on a control "typical" American diet, subjects (diastolic blood pressure [BP], 80 to 95 mm Hg; systolic BP, <160 mm Hg; mean age, 45 years) were randomly assigned to 1 of 3 diets for an 8-week intervention period: a continuation of the control diet; a diet rich in fruits and vegetables; and a "combination" diet that emphasized fruits, vegetables, and low-fat dairy products. We measured ABP at the end of the run-in and intervention periods. Both the fruit/vegetable and combination diets lowered 24-hour ABP significantly compared with the control diet (P<0. 0001 for systolic and diastolic pressures on both diets: control diet, -0.2/+0.1 mm Hg; fruit/vegetable diet, -3.2/-1.9 mm Hg; combination diet, -4.6/-2. 6 mm Hg). The combination diet lowered pressure during both day and night. Hypertensive subjects had a significantly greater response than normotensives to the combination diet (24-hour ABP, -10.1/-5.5 versus -2.3/-1.6 mm Hg, respectively). After correction for the control diet responses, the magnitude of BP lowering was not significantly different whether measured by ABPM or random-zero sphygmomanometry. Participant acceptance of ABPM was excellent: only 1 participant refused to wear the ABP monitor, and 7 subjects (2%) provided incomplete recordings. These results demonstrate that the DASH combination diet provides significant round-the-clock reduction in BP, especially in hypertensive participants.
Pulse Wave Propagation in the Arterial Tree

The beating heart creates blood pressure and flow pulsations that propagate as waves through the arterial tree that are reflected at transitions in arterial geometry and elasticity. Waves carry information about the matter in which they propagate. Therefore, modeling of arterial wave propagation extends our knowledge about the functioning of the cardiovascular system and provides a means to diagnose disorders and predict the outcome of medical interventions. In this review we focus on the physical and mathematical modeling of pulse wave propagation, based on general fluid dynamical principles. In addition we present potential applications in cardiovascular research and clinical practice. Models of short- and long-term adaptation of the arterial system and methods that deal with uncertainties in personalized model parameters and boundary conditions are briefly discussed, as they are believed to be major topics for further study and will boost the significance of arterial pulse wave modeling even more.
EFFECT OF AQUEOUS LEAF EXTRACT OF Moringa oleifera ON SOME RENAL FUNCTION INDICES OF RATS

Purpose:The study was designed to investigate the effect of aqueous leaf extract of M.oleifera on bile secretion and serum electrolytes in rats. Methodology: Eighteen (18) Albino Wistar rats weighing between 180220g body weights were assigned into three groups (i, ii and iii) of six rats each after acclimatization for seven (7) days. Group 1 (control) received standard feed and water while Groups 11 and 111 (low and high dose groups respectively) received 300mg/kg body weight and 600mg/kg body respectively in addition to food and water daily for 28days.The rats were sacrificed 24hours after an overnight fast using chloroform-ether anesthesia in ratio 1;1. The blood as well as biliary samples was collected for determination of electrolytes. Result: The result showed that bile secretion was significantly (P<0.001) increased in the high dose group but was significantly (P<0.001) decreased in the low dose group when compared with the control. The biliary bicarbonate level were significantly (P<0.001) decreased in test groups while there was significant (P<0.001) increased in serum bicarbonate levels compared with control. Serum and biliary phosphate levels were significantly (P<0.001) decreased in test groups compared with control. Sodium levels in serum and bile were significantly (P<0.001) decreased, while serum potassium levels were significantly (P<0.001) decreased in test groups but were significantly (P<0.001) increased test group compared with control. Serum bilirubin levels were significantly lowered in low dose but increased in high dose group compared with control. Uric acid levels in bile and serum were significantly (P<0.001) decreased in test groups. Creatinine was significantly reduced in low dose compared with control following the administration of the extract. Urea and T. cholesterol were significantly (P<0.001) reduced in serum but significantly increased in bile respectively.Conclusion: It appears that M.oleifera may reduce blood pressure following its marked effect on sodium levels
MR imaging relaxometry allows noninvasive characterization of in vivo differentiation of muscle precursor cells.

PURPOSE To demonstrate the feasibility of in vivo monitoring of the myogenic differentiation process from human muscle precursor cells to mature skeletal muscle tissue by measuring characteristic magnetic resonance (MR) imaging relaxation and diffusion properties as a potential noninvasive diagnostic tool in muscle cell therapy. MATERIALS AND METHODS The study was approved by the ethics committee for studies in humans and the animal care committee. The hypothesis was tested by means of subcutaneous injection of human muscle precursor cells from the rectus abdominis muscle into nude mice (n = 18). Animals injected with human fibroblasts, prostate cancer cells, or collagen served as control animals (four in each group). T1, T2, T2*, and apparent diffusion coefficients (ADCs) were measured at 4.7-T MR imaging. MR imaging parameters were statistically evaluated by using analysis of variance with Bonferroni correction. The engineered muscle was characterized by means of immunofluorescence, Western blot, and contraction assays. RESULTS Muscle tissue in the early stages of the differentiation process exhibited distinctly higher T1 (mean ± standard deviation, 2242 msec ± 116), T2 (224 msec ± 18), and T2* (33.3 msec ± 3.6) values and ADCs (1.53 × 10(-3) mm(2)/sec ± 0.03) compared with those of skeletal muscle. The muscle precursor cells exhibited a nonspecific pattern compared with that in control animals in the early stages. During differentiation, the relaxation and diffusion parameters decreased and approached the values for mature skeletal muscle tissue: T1, 1386 msec ± 88; T2, 32.0 msec ± 4.3; T2*, 10.8 msec ± 0.8; ADC, 1.39 × 10(-3) mm(2)/sec ± 0.02 (reference erector spinae muscle tissue: T1, 1417 msec ± 106; T2, 31.0 msec ± 2.4; T2*, 11.3 msec ± 1.7; and ADC, 1.40 × 10(-3) mm(2)/sec ± 0.03). CONCLUSION MR imaging relaxation and diffusion measurements can be used as potential biomarkers for noninvasive in vivo monitoring of the myogenic differentiation process from muscle precursor cells to mature skeletal muscle tissue in muscle cell therapy.
On the origin of aurorae on Mars

We report observations by Mars Global Surveyor (MGS) of thousands of peaked electron energy spectra similar to terrestrial auroral electrons. They are observed on the Martian nightside, near strong crustal magnetic sources. The spectra have peak energies ranging from 100 eV – 2.5 keV, and fluxes near the peak are 10–10000 times higher than typical nightside spectra. They occur on magnetic field lines that connect the shocked solar wind to crustal magnetic fields, and on adjacent closed field lines. Their detection is directly controlled by the solar wind, suggesting that magnetic reconnection is required for their observation. We calculate that the most energetic distributions could produce atmospheric emission with intensity comparable to that recently reported from the Mars Express (MEX) spacecraft. Half of the most energetic examples occur during the passage of space weather events past Mars, suggesting that a disturbed plasma environment is favorable for electron acceleration along magnetic field lines.
Skeletal muscle DHP receptor mutations alter calcium currents in human hypokalaemic periodic paralysis myotubes.

1. Mutations in the gene encoding the alpha 1‐subunit of the skeletal muscle dihydropyridine (DHP) receptor are responsible for familial hypokalaemic periodic paralysis (HypoPP), an autosomal dominant muscle disease. We investigated myotubes cultured from muscle of patients with arginine‐to‐histidine substitutions in putative voltage sensors, IIS4 (R528H) and IVS4 (R1239H), of the DHP receptor alpha 1‐subunit. 2. Analysis of the messenger ribonucleic acid (mRNA) in the myotubes from such patients indicated transcription from both the normal and mutant genes. 3. In control myotubes, the existence of the slow L‐type current and of two rapidly activating and inactivating calcium current components (T‐type with a maximum at about ‐20 mV and ‘third type’ with a maximum at +10 to +20 mV) was confirmed. In the myotubes from patients with either mutation, the third‐type current component was seen more frequently and, on average, with larger amplitude. 4. In myotubes with the IVS4 mutation (R1239H) the maximum L‐type current density was smaller than control (‐0.53 +/‐ 0.31 vs. ‐1.41 +/‐ 0.71 pA pF‐1). The voltage dependence of activation was normal, and hyperpolarizing prepulses to ‐120 mV for 20 s did not increase the reduced current amplitude during test pulses. 5. In myotubes with the IIS4 mutation (R528H) the L‐type current‐voltage relation, determined at a holding potential of ‐90 mV, was normal. However, the voltage dependence of inactivation was shifted by about 40 mV to more negative potentials (voltage at half‐maximum inactivation, V1/2 = ‐41.5 +/‐ 8.2 vs. ‐4.9 +/‐ 4.3 mV in normal controls). (ABSTRACT TRUNCATED AT 250 WORDS)
Wavelet Based Feature Extraction Technique for Face Recognition and Retrieval : A Review Mr .

With enormous growth in video applications, a huge amount of video data is being generated every day. The proposed work is inspired from the same issuein concern face recognition and retrieval. The features are always plays an important role. Meanwhile, most of the features are directly proportional to the accuracy and inversely proportional to the speed.Wavelets have finds third way to find eminent solution to such problems. The goal of proposed work is to systematically address the recent work of face recognition and retrieval with Wavelet, through evaluation that permits a meaningful objective comparison of techniques, provides the research community with sufficient data for the exploration of automatic modeling techniques. The outcome of the paper which fulfilled the three objectives-i) study the recent of recent techniques based on Wavelets ii) analyzed the status recent techniques with respect to results and performance with respect to Wavelet iii)various applications based on wavelet based feature extraction Finally, iv) identification of most feasible and optimized technique along with discussion for betterment. Mean while, objective evaluation would be extremely useful to the computer vision research community for years to come.
The role of timely measurement of galectin-3, NT-proBNP, cystatin C and hsTnT in predicting prognosis and heart function after heart transplantation

Abstract Background: Changes of biomarkers measured soon after heart transplantation (HTx) can reflect different processes: cardiomyocyte necrosis (troponins, high-sensitivity cardiac TnT and TnI), heart function (natriuretic peptides, BNP and NT-proBNP), fibrosis (galectin-3 and ST2), and global cardiorenal risk (cystatin C). We assessed the prognostic role of hsTnT, NT-proBNP, galectin-3 and cystatin C during the early post-transplant period. Methods: A total of 121 consecutive post-HTx patients were assessed. The main outcomes were survival, left ventricular ejection fraction (LVEF) and rejection periods. Survival was assessed after intermediate (12 months) and long periods (total follow-up during study, median of survival 763 days, IR 527–1038 days). LVEF was assessed 12 months after HTx. Rejection was evaluated during follow-up. We report biomarker concentrations measured 10 days and 12 months after HTx. Results: Ten days after HTx, cystatin C and hsTnT predicted death both under univariable and multivariable analysis. These two biomarkers along with galectin-3 were increased in patients with decreased LVEF measured 1 year after HTx. NT-proBNP did not show early prognostic power. None of the measured biomarkers predicted rejection, but hsTnT and NT-proBNP were increased significantly 12 months after HTx in patients with at least one rejection. Conclusions: Cystatin C and hsTnT measured 10 days after HTx can provide prognostic information on survival and galectin-3 measured at the same time may display a relationship to heart function assessed 1 year after HTx. Further study should be carried out in a large cohort of patients.
The acquisition of Italian morphology: a reply to Hyams

In Pizzuto & Caselli (1992, hereafter: P&C) we provided an overview of morphological development in Italian, focusing on three aspects of free speech production (verbs, pronouns and articles), in the longitudinal records of three children. We analysed our data using criteria appropriate to allow reliable cross-linguistic comparisons with data from English. By this means we evaluated the plausibility of a nativist, parameter-setting account of language development in Italian and English, as proposed for these two languages by Hyams (1986a b; 1987; 1988). We concluded that our data did not support the strong predictions made within such a parameter-setting account, and that the developmental patterns observed were best explained by a combination of cognitive, perceptual and distributional factors of the sort that are proposed in most other models of language acquisition.
Cervical Disc Arthroplasty Versus Anterior Cervical Discectomy and Fusion for Incidence of Symptomatic Adjacent Segment Disease: A Meta-Analysis of Prospective Randomized Controlled Trials

Study Design. Meta-analysis of randomized controlled trials. Objective. To evaluate the reported rate of adjacent segment disease (ASD) of cervical disc arthroplasty (CDA) compared with anterior cervical discectomy and fusion (ACDF). Summary of Background Data. Motion-maintaining technologies such as CDA have developed rapidly because of the concern of ASD. Till date, however, it still has been under debate whether CDA is superior to ACDF regarding the incidence of ASD. Methods. We comprehensively searched PubMed, EMBASE, and Cochrane Central Register of Controlled Trails for prospective randomized controlled trials (RCTs) that reported the incidence of ASD between CDA and ACDF. The retrieved results were last updated on November 20, 2015 without language restrictions. Two independent authors selected qualified studies, assessed methodological quality, and extracted requisite data. Results. Fourteen relevant RCTs involving 3235 individuals with a follow-up period of 2 to 7 years were included in the meta-analysis (1696 in CDA group and 1539 in ACDF group). The outcomes indicated that CDA was superior to ACDF considering the lower rate of ASD (risk ratio, 0.57; 95% confidence interval, 0.37 to 0.87; P = 0.009). And compared with ACDF, there were significantly fewer adjacent segment reoperations in the CDA group (risk ratio, 0.47; confidence interval, 0.32 to 0.70; P = 0.0002). Subgroup analysis stratified by different types of disc prostheses was also performed. Conclusion. CDA was superior to ACDF regarding fewer ASDs and relative reoperations on the basis of available evidence from a meta-analysis of 14 RCTs. CDA may be a better surgical procedure to reduce the incidence of ASD for patients with cervical disc disease compared with ACDF. Further well-designed studies should continue to pay attention to excellent patients with longer-term follow-up to evaluate the incidence of ASD of these two procedures. Level of Evidence: 1
Temporal Characteristics Related to Leave from Work and Pregnancy among Mothers with Congenitally Malformed Offspring

The possible impact of occupational factors on the furtherance of congenital defects has been under study at our department for the past 4 years. The topic has assumed a special interest because of the importance of the issue involved, namely the search for a possibility to prevent teratogenesis, and partly because the applicable methods are different from those of ‘customary’ epidemiology. In connection with a register-based, case-referent study utilizing supplementary information, acquired via questioning, of conditions at the mothers' work places, we analysed various time-related events in their pregnancy. We found that the groups compared differed from each other with regard to the correct timing of the births, despite the fact that the distribution of the times of stopping work for various reasons were alike. Among mothers who were granted sick leave from work the diagnosis of anencephaly became less common close to the estimated date of delivery, and conversely for the diagnosis of hydrocephaly. The findings of the present study may suggest that the time of assignment for a statutory maternity leave be considered. Methodological issues in study design are also briefly discussed.
Characterization of Nb-doped MgZnO films grown by a radio-frequency magnetron sputtering system

Niobium-doped MgxZn1-xO (Nb-MZO) mixed oxide films with high transmittance were successfully deposited on sapphire substrates by a radio-frequency (RF) magnetron sputtering using a 4-in ZnO/MgO/NbOx (75/20/5 wt %) target. In this study, the films were analyzed through a Hall test, X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and transmittance. The XRD results showed MgO2 (002) wurtzite peak as well as an MgxZn1-xO (111)-cubic peak. The absorption edges of these Nb-MZO films were located in the UV region, implying that the MgO content of the Nb-MZO layer increased the bandgaps. The XPS spectra of Nb-MZO films were also used to analyze the composition of the as-grown and annealed Nb-MZO films. These results indicate that the Nb-MZO films are ideal for use as transparent contact layers.
Benign Soft Tissue Lesions of Oral Cavity: A Histopathological Study

Background: To describe the histopathological types and frequency of the most common benign tumours of oral cavity reporting to the government referral hospital at Miraj in Maharashtra state. Materials and Methods: A retrospective analysis was made of the five year records of reports of oral biop-sy samples of patients maintained by the department of pathology. The data obtained was compiled for age, gender, site of the lesion and the histopathology features of the lesions. Results: Seventy of the 642 biopsy samples of the oral lesions reported in this five year period were categorised as benign oral tumours. Fibro-ma (48.6%) followed by squamous papilloma (28.6%) were found to be the commonest benign tumours. The buccal mucosa was the most commonest site of these benign tumours (44.3%). Conclusions: Fibroma is the commonest benign tumour of the oral cavity reporting to the referral government hospital at Miraj in Maharastra state. Keywords: Benign oral tumour, fibroma, oral cavity, soft tissue lesion, histopathology
Psychological bulletin.

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The P gene of human parainfluenza virus type 1 encodes P and C proteins but not a cysteine-rich V protein

The nucleotide sequence of the P gene of human parainfluenza virus type 1 (PIV1) was determined from cloned cDNA copies of the mRNA. By analogy with the gene organization of Sendai virus, two open reading frames in the mRNA sense of the gene were identified as coding sequences for the P protein (568 amino acids with an estimated molecular weight of 64,655) and the C protein (204 amino acids with an estimated molecular weight of 24,108). Comparison of the deduced amino acid sequences of the P and C proteins of PIV1 with those of Sendai virus showed a high degree of homology. However, a sequence for the cysteine-rich V protein, which was considered a common feature of other paramyxoviruses, was interrupted by the presence of multiple stop codons. The sequence analysis of three P-gene-specific cDNA clones generated from genomic RNA by polymerase chain reaction and one additional clone generated from mRNA confirmed that the coding sequence for the cysteine-rich region is silent in the PIV1 gene and thus is not translated into protein. Two potential editing sites with the consensus sequence 3'UUYUCCC were found in the PIV1 P gene at positions 564 to 570 and 1430 to 1436. However, examination of the PIV1 mRNA population by a primer extension method indicated that neither of these sites is utilized. These results indicate that the PIV1 P gene has a coding strategy different from those of other paramyxovirus P genes.
An Ergonomics Approach for the Design of Manual Materials-Handling Tasks

The frequency, severity, and cost of manual materials-handling (MMH) injuries dictate that the design of these tasks and the assignment of employees to them ensure that the demands of the job do not exceed the capacity of the worker. This paper proposes the use of the job Severity Index (JSI) as a tool for job design and employee placement. The JSI is defined as the time- and frequency-weighted average of the maximum weight required by each task divided by the selected lifting capacity given the lifting task conditions. This paper illustrates the relationship between the JSI and the frequency, severity, and cost of MMH injuries. Procedures for job design and employee placement based on the JSI are discussed and examples of the use of the JSI in industry are given.
Detoxification of Motor Vehicle Exhaust and Suicide

Lester and Murrell ( 1980) have argued that restricting the availability of the means for completing suicide may be an excellent way of preventing suicide. They reported that stricter handgun controls in the 48 continental states were associated with a lowered suicide rate. Recent data on the effects of emission controls on automobiles in the USA are consistent with this idea. Landers ( 1981) noted that the carbon monoxide content of car exhaust was 8.5% before 1968, 3.0% during 1975-1979, and 0.5% by 1980. While thc numter of people killing themselves using motor vehicle exhaust gases in the USA has remained roughly constant from 1965 to 1979 (2120 in 1965 and 1929 in 1979), the total number of suicides has risen in the same period from 21,501 in 1965 to 27,206 in 1979. Thus, che percentage of suicides using motor vehicle exhaust has dropped from 9.9% in 1965 to 7.1% in 1979. As motor vehicle exhaust in the USA has become less toxic, a smaller percentage of suicides seem to be using it as a means of killing themselves. This makes an interesting contrast with the situation in Britain where car exhaust suicides have more than tripled during the same period (Bulusu & Alderson, 1984). This may to some extent reflect increased ownership of cars, more homes with garages and possibly the increased popularity of hatchback and estate cars which permit rhe easier introduction of the exhaust gases into the passenger compartment. Another possible reason is that knowledge about this method of suicide has spread.