Miracle-dz/UniFAR-FTUs huggingface dataset:
Intra-myocellular Triacylglycerol LBSQ Lower-body Subcutaneous Fat LPL Lipoprotein Lipase SA Specific Activity TG Triglyceride VLDL Very Low Density Lipoprotein VLDL-TG Very Low Density Lipoprotein Triglyceride

This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/sms.12859 This article is protected by copyright. All rights reserved. DR ESBEN SONDERGAARD (Orcid ID : 0000-0001-8041-6994)
O-GlcNAcylation enhances the tumorigenic properties of cervical cancer cells in vitro

Cervical cancer is the leading cause of cancer-related death in women world-wide. Recently, the post-translational modification, β-N-acetylglucosaminylation (O-GlcNAcylation), has been discovered in many types of epithelial cancers, including those of the female reproductive tract, but the role it potentially plays in cellular growth and metastasis is unclear. This study investigated the effect of global O-GlcNAcylation on the tumorigenic properties of the cervical cancer cell line, SiHa; including cytokeratin 8/18 (K8/18) intermediate filaments as a potential target. Overall, inhibition of O-GlcNAcylation (via the inhibitor, OSMI-1) in SiHa cells impaired cell proliferation (p<0.01) and invasion (p<0.01), yet did not affect cell cycle progression. These effects occurred concomitantly with an alteration of cellular morphology, principally the disruption/decline of K8/18 and β-actin filament expression. The results suggest O-GlcNAcylation regulates several aspects of tumorigenesis in cervical cancer cells, and cytoskeletal proteins are among the targets. Correspondence to: Nicole Morin Jaskiewicz, University of Vermont, Terrill Building Rm 230, 570 Main St., Burlington, VT, USA, Tel: 802-656-5892; Fax: 802-656-8196; E-mail: nll22@wildcats.unh. edu
Energy Conversion in Shape Memory Alloy Heat Engine Part I: Theory

Shape Memory Alloy (SMA) can be easily deformed to a new shape by applying a small external load at low temperature, and then recovers its original configuration upon heating. This unique shape memory phenomenon has inspired many novel designs. SMA based heat engine is one among them. SMA heat engine is an environment-friendly alternative to extract mechanical energy from low-grade energies, for instance, warm wastewater, geothermal energy, solar thermal energy, etc. The aim of this paper is to present an applicable theoretical model for simulation of SMA-based heat engines. First, a micro-mechanical constitutive model is derived for SMAs. The volume fractions of austenite and martensite variants are chosen as internal variables to describe the evolution of microstructure in SMA upon phase transition. Subsequently, the energy equation is derived based on the first thermodynamic law and the previous SMA model. From Fourier’s law of heat conduction and Newton’s law of cooling, both differential and integral forms of energy conversion equation are obtained.
BLOOD GLUCOSE RESPONSES OF TYPE-2 DIABETICS DURING AND AFTER EXERCISE PERFORMED AT INTENSITIES ABOVE AND BELOW ANAEROBIC THRESHOLD RESPOSTA GLICÊMICA DE DIABÉTICOS TIPO 2 DURANTE E APÓS EXERCÍCIOS REALIZADOS EM INTENSIDADES ACIMA E ABAIXO DO LIMIAR ANAERÓBIO

With the objective of analyzing the blood glucose responses during and after exercise performed at 90 and 110% of anaerobic threshold (AT), 10 type-2 diabetes patients (56.9±11.2years; 80.3±14.4kg) performed an incremental test (IT) on a cycle ergometer. After an initial IT to identify AT, the volunteers participated in three experimental sessions on three different days: 20 minutes’ of cycling at either 90 or 110% of AT, and a control session (CON). Blood glucose was measured at rest, and at the 10th and 20th minutes of exercise or control condition, as well as every 15 minutes during a 2-hour postexercise recovery period (Rec). One-way ANOVA did not detect signifi cant differences in blood glucose levels between the sessions at 90 and 110% of AT. Compared to CON, a signifi cant decrease was observed at the 20th minute of exercise, and at the 15 th and 60 th minutes of Rec from the 90% AT session. Signifi cant reductions were also observed at the 10 th
Particle transport in fluidized beds: experiments and stochastic models

Fluidization is a process in which solids are caused to behave like fluid by blowing gas or liquid upwards through the solid-filled reactor. The behavior of a bed of particles within the reactor during the process is very complex and difficult to predict. To make sure that a fluidized bed reactor is optimally efficient, normally a pilot model of the proposed reactor is made and tested before an actual reactor is built. Alternatively, a mathematical model can be used to investigate performance of the planned reactor. Physical modeling using a pilot reactor can be expensive, time consuming, and its accuracy may suffer from scaling problems. On the other hand, mathematical modeling is economical, convenient, but accuracy of the performance prediction is the primary concern. Zie: Summary
Regional and technological effects of cooperation behavior

In this paper we investigate the determinants of cooperative innovation and put our main focus on the regional or spatial and on the technological or sectoral dimension. We suggest a method to disentangle these two factors and to extract differential regional effects. The latter can be used to identify and evaluate the strength of regional innovation systems. Applying this method to German patent data we find evidence that regional differences in the degree of cooperative innovation are not only due to the technological/sectoral composition of the region but also due to a specific regional effect.
Arabidopsis thaliana contribute to defense-associated differential gene expression in cepacia Burkholderia Distinct carbohydrate and lipid-based molecular patterns within lipopolysaccharides from

Lipopolysaccharides are structural components within the cell walls of Gram-negative bacteria. The LPSs as microbeassociated molecular pattern (MAMP) molecules can trigger defense-related responses involved in MAMP-triggered immunity and basal resistance in plants, presumably from an initial perception event. LPS from Burkholderia cepacia as well as two fragments, the glycolipid, lipid A and the polysaccharide (OPS-core) chain, were used to treat Arabidopsis thaliana seedlings to evaluate the eliciting activities of the individual LPS sub-domains by means of Annealing Control Primer-based Differential Display transcript profiling. Genes found to be up-regulated encode for proteins involved in signal perception and transduction, transcriptional regulation and defense – and stress responses. Furthermore, genes encoding proteins involved in chaperoning, secretion, protein–protein interactions and protein degradation were differentially expressed. It is concluded that intact LPS, as well as the two sub-components, induced the expression of a broad range of genes associated with perception and defense as well as metabolic reprogramming of cellular activities in support of immunity and basal resistance. Whilst the lipid A and OPS moieties were able to up-regulate sub-sets of defense-associated genes over the same spectrum of categories as intact LPS, the up-regulation observed with intact LPS was the more comprehensive, suggesting that the lipid A and glycan molecular patterns of the molecule act as partial agonists, but that the intact LPS structure is required for full agonist activity.
Factors Affecting the Information Security Awareness and Perceived Information Security Risk of Employees of Port Companies

The purpose of the present study is to empirically examine factors that affect the information security awareness and perceived information security risk of employees of port companies. In particular, in order to identify factors that affect the perceived information security risks, we investigated the relation of assets, threats, and vulnerabilities to it, using the risk analysis methodology. With A total of 252 valid questionnaires, we also performed the structural equation modeling analysis using AMOS. It was found that first, there was no meaningful relationship between the information assets and the perceived information security risk in the case of employees of port companies. Second, threats and vulnerabilities turned out to have positive influences on the perceived information security risk. Finally, there was a positive relationship not only between the information security awareness and the information security education, but also between the information security awareness and the intention of information security. However, there was no meaningful relationship between the information security concern and the information security awareness.
Reference values for the 6-min walk test in healthy middle-aged and older adults: from the total distance traveled to physiological responses

Abstract Introduction: Physiological responses to the 6-min walk test (6MWT) have been increasingly evaluated in patients with cardiopulmonary diseases. However, previous studies did not include healthy persons. Objective: To evaluate the intensity of 6MWT, to develop a series of predictive equations for the physiological variables and to test their reliability in healthy middle-aged and older adults. Method: We evaluated 102 non-trained healthy adults (54 women, aged 61 ± 10 years) and a cross-validation sample of 30 participants. We measured physiological responses to the 6MWT and a cardiopulmonary exercise testing (CPET) on a treadmill. Results: The R2 values for regression analysis adjusted by age, body mass, stature, and sex ranged from 0.25 for heart rate and 0.46 for peak V ˙ O 2 The 6MWT distance and 6MWT peak V ˙ O 2 represented 110 ± 10% and 102 ± 15% of the predicted values, respectively, using our equations. The intensity of 6MWT corresponded to 72 ± 13% of the peak O2 and 78 ± 23% of the peak HR in the CPET. Peak V ˙ O 2 in the CPET was adequately predicted by 6MWT peak V ˙ O 2 (R2 = 0.76) and 6MWD (R2 = 0.54). Conclusion: The 6MWT represents a moderate to high-intensity test in middle-aged and older healthy adults and is valid for assessing maximal aerobic exercise capacity. Physiological responses to the 6MWT may be adequately predicted with a combination of anthropometrics and demographics.
Monitoring dusty sources in the vicinity of Sagittarius A*

Context. Several dusty infrared sources traced on their orbits around Sgr A* with SINFONI and NACO mounted at the VLT/Chile show near-infrared (NIR) excess and Doppler-shifted line emission. We investigate these sources in order to clarify their nature and compare their relationship to other observed NIR objects close to Sgr A*. Aims. Using SINFONI, we are able to determine the spectroscopic properties of the dusty infrared sources. Furthermore, we can extract spatial and velocity information of these objects. We are able to identify X7, X7.1, X8, G1, DSO/G2, D2, D23, D3, D3.1, D5, and D9 in the Doppler-shifted line maps of the SINFONI H + K data. From our K- and L′-band NACO data, we derive the related magnitudes of the brightest sources located west of Sgr A*. Methods. For determining the line of sight velocity information and to investigate single emission lines, we used the near-infrared integral field spectrograph SINFONI datasets between 2005 and 2015. For the kinematic analysis, we used NACO datasets from the years between 2002 and 2018. This study was done in the H, Ks, and L′ band. From the 3D SINFONI data-cubes, we extracted line maps in order to derive positional information for the sources. In the NACO images, we identified the dusty counterpart of the objects. When possible, we determined the Keplerian orbits and applied a photometric analysis. Results. The spectrum of the investigated objects show a Doppler-shifted Brγ and HeI line emission. For some objects west of Sgr A*, we additionally find [FeIII] line emission that can be clearly distinguished from the background. A one-component blackbody model fits the extracted near-infrared flux for the majority of the investigated objects, with the characteristic dust temperature of 500 K. The photometric derived H- and KS-band magnitudes are between magH > 22.5 and magk = 18.1+0.3−0.8 for the dusty sources. For the H-band magnitudes we can provide an upper limit. For the bright dusty sources D2, D23, and D3, the Keplerian orbits are elliptical with a semi-major axis of aD2 = (749 ± 13) mas, aD23 = (879 ± 13), and aD3 = (880 ± 13) mas. For the DSO/G2, a single-temperature and a two-component blackbody model is fitted to the H-, K-, L′-, and M-band data, while the two-component model that consists of a star and an envelope fits its SED better than an originally proposed single-temperature dusty cloud. Conclusions. The spectroscopic analysis indicates that the investigated objects could be dust-embedded pre-main-sequence stars. The Doppler-shifted [FeIII] line can be spectroscopically identified in several sources that are located between 17:45:40.05 and 17:45:42.00 in Dec However, the sources with a DEC less than 17:45:40.05 show no [FeIII] emission. Therefore, these two groups show different spectroscopic features that could be explained by the interaction with a non-spherical outflow that originates at the position of Sgr A*. Following this, the hot bubble around Sgr A* consists out of isolated sources with [FeIII] line emission that can partially account for the previously detected [FeIII] distribution on larger scales.
Deep-water clastic systems in the Upper Carboniferous (Upper Mississippian–Lower Pennsylvanian) Shannon Basin, western Ireland

The Upper Carboniferous Shannon Basin of western Ireland contains a more-than-2300-m-thick (7540 ft) basin-fill succession, shallowing upward from deep-water to deltaic and incised fluvial deposits. The deep-water basin floor and slope succession is world renowned as an analog for hydrocarbon-bearing deep-water sandstones on several continental margins such as the basins in East and West Africa, South America, the Gulf of Mexico, and not least offshore northwest Europe. The Shannon Basin is frequently visited by both academia and industry for research and training purposes. A series of behind-outcrop research boreholes reveals the subsurface expression of the deep-water rocks and is complemented by seismic-scale cliff exposures. The succession is interpreted as a first-order basin-scale linked sedimentary system. This system can be analyzed using the principles of source-to-sink analysis and leaves the visitor with a complete picture of the basin fill, enhanced by spectacular sedimentological and stratigraphic detail.
A poliploidia artificial na obtenção de melancia sem sementes

Watermelons (Citrullus vulgaris Schrad.) are in general provided with numerous seeds: large in the "American" varieties and small in the "Japanese" varieties. Triploids (2n=33) of the "Japanese" varieties are already under cultivation by American farmers who import the hybrid seeds from Japan and seedless fruits are being produced in ever increasing amounts. In Brazil the Japanese diploid (2n=22) varieties are only of recent introduction; among the American varieties (2n=22), "Keckley Sweet" is one of the best known and preferred for its good taste. For the obtention of seedless watermelons it seemed advisable to start the work with such a variety because of its commercial significance. The first step was the obtention of tetraploids (2n=44); the adopted method consisted in the treatment of germinating seeds in an aqueous colchicine solution; best results were achieved using an 0.1% solution for 8 to 12 hours. The tetraploids are of more stunted growth, with larger leaves and flowers; the fruits are smaller, round and few-seeded. In attempting to cross tetraploids with diploids, successfull results were obtained when ♀ 4n flowers were pollinated with pollen from 2n plants. Triploid (2n=33) plants, obtained from hybrid seeds, were completely male sterile but set fruits when pollinated with pollen from 2n plants. The triploid plants are somewhat intermediate between di- and tetraploids as to the size of leaves and growth habit; the fruits are less elongated than in the diploids and not round as in the tetraploids. Some fruits are seedless, i.e. with aborted seeds that can be eaten together with the pulp; others show from few to many empty seeds which are flacid, but not quite fit to be eaten. Comparative studies have been made of pollen, stomata and seeds of 2n, 3n and 4n plants. Studies are in progress to solve some problems encountered in the mass production and germination of tetraploid and triploid seed; up to now they are handicaps to the commercial utilization of these "seedless watermelons".
Conception Patients Attempting Medically Assisted Spermatozoon Fractions of Semen from C Virus RNA in Seminal Plasma and Detection and Characterization of Hepatitis

10.1128/JCM.40. 9.3252-3255.2002. 2002, 40(9):3252. DOI: J. Clin. Microbiol. Laurent, Jean-François Guerin and Bruno Pozzetto Tardy, Florence Grattard, Hélène Cordonier, Jean-Louis Thomas Bourlet, Rachel Levy, Anne Maertens, Jean-Claude Conception Patients Attempting Medically Assisted Spermatozoon Fractions of Semen from C Virus RNA in Seminal Plasma and Detection and Characterization of Hepatitis
Crustal structure and tectonic evolution of the Tornquist Fan region as revealed by geophysical methods

Crustal structure derived primarily from geophysical investigations reveals features that may be related to the complex tectonic evolution of the Tornquist Fan region. This northwestwards widening splay of Late Carboniferous – Early Permian fault zones in the Danish region emanates from the Teisseyre-Tornquist Zone in northern Poland. Seismic reflections and velocity anomalies image collisional fault zones that formed during the Proterozoic and Palaeozoic amalgamation of the crust. Re-equilibration of Moho appears to have taken place before late Palaeozoic rifting and magmatism initiated the main phase of basin formation that continued into the Mesozoic. The resulting, strong Moho topography, with variation between depths of 26 and 48 km, has been practically “frozen in” since then, although the late Cretaceous – early Cenozoic inversion tectonics may have formed a crustal keel underneath part of the Sorgenfrei-Tornquist Zone which cuts across the Proterozoic crust of the Tornquist Fan region.
calibrations for assessment of oil , phenols , glucosinolates and fatty acid content in the intact seeds of oilseed Brassica species Running title : NIRS based estimation of quality parameters in Brassica

Rahul Sen, Sanjula Sharma*, Gurpreet Kaur, S.S. Banga Department of Plant Breeding and Genetics, Punjab Agricultural University, Ludhiana141004, Punjab, India. *Correspondence to: Sanjula Sharma, Department of Plant Breeding and Genetics, Punjab Agricultural University, Ludhiana-141004, Punjab, India. Email:drsanjula@pau.edu Abstract BACKGROUND: Very few NIRS calibration models are available for non-destructive estimation of seed quality traits in B. juncea. The available ones also fail to adequately discern variation for oleic acid (C18:1), linolenic (C18:3) fatty acids, meal glucosinolates and phenols. We report the development of a new NIRS calibration equation that is expected to fill the gaps in the existing NIRS equations.
Author ’ s Accepted Manuscript White matter microstructural deficits in 22 q 11 . 2 deletion syndrome

Cite this article as: David R. Roalf, J. Eric Schmitt, Simon N. Vandekar, Theodore D. Satterthwaite, Russell T. Shinohara, Kosha Ruparel, Mark A. Elliott, Karthik Prabhakaran, Donna M. McDonald-McGinn, Elaine H. Zackai, Ruben C. Gur, Beverly S. Emanuel and Raquel E. Gur, White matter microstructural deficits in 22q11.2 deletion syndrome, Psychiatry Research: Neuroimaging, http://dx.doi. org/10.1016/j.pscychresns. 2017.08. 001
Evaluation of some medicinal plants against Escherichia coli, Salmonella spp. and Staphylococcus aureus

Since the beginning of human civilization, medicinal plants have been used by mankind for its therapeutic value and even in modern times have formed the basis of many pharmaceuticals in use. The aim of the present study was to evaluate the antimicrobial activity of different extracts of Piper betle, Boerhavia diffusa, Oxalis corniculata, Centella asiatica, Camellia sinensis, Curcuma longa and Allium cepa traditionally used in Bangladesh. The antimicrobial activity of these different solvent extracts were tested against Gram-positive (Staphylococcus aureus) and Gramnegative bacterial species (Escherichia coli and Salmonella spp.) by observing the zone of inhibition by disc diffusion method. The tested bacterial species were isolated from hospital waste water sample and fresh poultry meat samples where Chloramphenicol was used as standard for antibacterial assay. The results of the study revealed that the ethanolic, methanolic, and aqueous extracts of almost all the seven herbal species successfully showed to be effective against the tested Gram-positive and Gram-negative bacteria with only negative result observed in case of Centella asiatica. The methanolic and water extract of Boerhavia diffusa was found to be slightly effective producing a shorter zone of inhibition. Among these medicinal plant products, Camellia sinensis and Piper betle was found to be more effective against the tested bacterial species where methanolic extracts showed maximum zone of inhibition against Gram-positive (S. aureus with zone of inhibition of 12 mm and 11 mm respectively) and Gram-negative bacteria (e.g. Salmonella spp. with zone of inhibition of 16 mm and 14 mm). The result confirmed the presence of antibacterial activity of Piper betle extract and other five medicinal plant extracts against various human pathogenic bacteria which should be further tested for other pathogenic multi drug resistant bacteria and could be used as an effective biocontrol agent in future.
Analytic continuation of multiple zeta-functions and their values at non-positive integers by

for positive integers si (i = 1, . . . , k) and sk ≥ 2. These values have a certain connection with topology and physics, and algebraic relations among them are extensively studied (see [18], [19], [6], [7] and [14]). Recently, Y. Ohno developed a unified algebraic relation in [16]. It is also interesting to consider it for complex variables si. In this paper, we deal with analytic continuation of ζk(s1, . . . , sk). Analytic continuation of ζ2(s1, s2) was proved by F. V. Atkinson [5] with applications to the study of the asymptotic behavior of the “mean values” of zeta-functions. See also Y. Motohashi [15] and M. Katsurada & K. Matsumoto [13]. In [4], T. Arakawa & M. Kaneko used analytic continuation of ζk(s1, . . . , sk) as a function of one variable sk when s1, . , sk−1 are positive integers, and discussed the relation among generalized Bernoulli numbers. On the other hand, S. Egami discussed the relationship among various multiple zeta-functions introduced by E. W. Barnes, T. Shintani and D. Zagier. (See [9] and [10].) However, for a general k, we have not found the proof of analytic continuation of ζk(s1, . . . , sk) as a function of k variables in the literature (but see the comment of Zagier [18, p. 509, lines 14–19]). We shall show that the multiple zeta-function can be continued analytically to Ck and discuss interesting properties of multiple zeta values at non-positive integers.