Miracle-dz/UniFAR-FTUs huggingface dataset:
The impact of ego-involvement in the creation of false childhood memories

An experiment employed a "familiar-informant false-narrative procedure" to examine the effects of ego involvement manipulation on the creation of false memories for suggested events. Our main sample consisted of 54 Serbian adolescent students. During the pre-testing stage, students’ parents (N=54) provided details from their children childhoods, which were used to create stimuli for the subsequent stages. Half of the participants were given an ego-involving suggestion- a short written statement that claimed that people with higher intelligence have a better and more detailed memory of their childhood. We hypothesized that ego-involved group would recollect more childhood events in general, create more false memories and be more confident in its’ authenticity and clarity. Implanted event was recognized as autobiographic by 24% respondents in the testing stage and by 44.4% respondents in the retesting stage. There were significant qualitative differences between authentic and false memories: authentic memories were assessed as more reliable and clearer than the false ones. Ego-involvement manipulation had no impact on the frequency or quality of false memories reported by the participants. Even though the specific ego-involvement manipulation was not successful, our findings suggest that other motivating strategies we employed pushed the respondents into accepting false memory suggestion in the retesting stage. Future research could benefit from testing more elaborate ego-involving procedures.
Clinical effect of autologous platelet-rich fibrin in the treatment of intra-bony defects: a controlled clinical trial.

AIM Platelet-rich fibrin (PRF) may be considered as a second-generation platelet concentrate widely used to accelerate soft and hard tissue healing because of presence of many growth factors. The present study aimed to investigate the clinical and radiological effectiveness of autologous PRF in the treatment of intra-bony defects of chronic periodontitis patients. MATERIAL AND METHODS Thirty-two intra-bony defects (one site/patient) were treated either with autologous PRF or a conventional open flap debridement alone. Clinical parameters such as plaque index (PI), sulcus bleeding index (SBI), probing depth (PD), clinical attachment level (CAL) and gingival marginal level (GML) were recorded at baseline and 9 months post-operatively. In both the groups, by using the image analysis software intra-bony defect fill was calculated on standardized radiographs (from the baseline and 9 months). RESULTS For all clinical and radiographic parameters test group was performed better than control group, and the difference was found to be statistically significant. Furthermore, images analysis revealed significantly greater bone fill in the test group compared with control (46.92%versus 28.66 %). Mean PD reduction (4.56 ± 0.37>3.56 ± 0.27) and CAL gain (3.69 ± 0.44>2.13 ± 0.43) in test group was found to be more compared with that of control group. In the test group, PD of >4 mm has highest percentage of PD reduction (68.9%) and CAL gain (61.6%). On frequency distribution analysis, there was no more difference for PD reduction in both the groups but CAL gain was much more in the test group than the control group. CONCLUSIONS Within the limit of the present study, there was greater reduction in PD, more CAL gain and greater intra-bony defect fill at sites treated with PRF than the open flap debridement alone.
LRRN4 and UPK3B Are Markers of Primary Mesothelial Cells

Background Mesothelioma is a highly malignant tumor that is primarily caused by occupational or environmental exposure to asbestos fibers. Despite worldwide restrictions on asbestos usage, further cases are expected as diagnosis is typically 20–40 years after exposure. Once diagnosed there is a very poor prognosis with a median survival rate of 9 months. Considering this the development of early pre clinical diagnostic markers may help improve clinical outcomes. Methodology Microarray expression arrays on mesothelium and other tissues dissected from mice were used to identify candidate mesothelial lineage markers. Candidates were further tested by qRTPCR and in-situ hybridization across a mouse tissue panel. Two candidate biomarkers with the potential for secretion, uroplakin 3B (UPK3B), and leucine rich repeat neuronal 4 (LRRN4) and one commercialized mesothelioma marker, mesothelin (MSLN) were then chosen for validation across a panel of normal human primary cells, 16 established mesothelioma cell lines, 10 lung cancer lines, and a further set of 8 unrelated cancer cell lines. Conclusions Within the primary cell panel, LRRN4 was only detected in primary mesothelial cells, but MSLN and UPK3B were also detected in other cell types. MSLN was detected in bronchial epithelial cells and alveolar epithelial cells and UPK3B was detected in retinal pigment epithelial cells and urothelial cells. Testing the cell line panel, MSLN was detected in 15 of the 16 mesothelioma cells lines, whereas LRRN4 was only detected in 8 and UPK3B in 6. Interestingly MSLN levels appear to be upregulated in the mesothelioma lines compared to the primary mesothelial cells, while LRRN4 and UPK3B, are either lost or down-regulated. Despite the higher fraction of mesothelioma lines positive for MSLN, it was also detected at high levels in 2 lung cancer lines and 3 other unrelated cancer lines derived from papillotubular adenocarcinoma, signet ring carcinoma and transitional cell carcinoma.
Interference and Memory Capacity Limitations

Working memory (WM) is thought to have a fixed and limited capacity. However, the origins of these capacity limitations are debated, and generally attributed to active, attentional processes. Here, we show that the existence of interference among items in memory mathematically guarantees fixed and limited capacity limits under very general conditions, irrespective of any processing assumptions. Assuming that interference (a) increases with the number of interfering items and (b) brings memory performance to chance levels for large numbers of interfering items, capacity limits are a simple function of the relative influence of memorization and interference. In contrast, we show that time-based memory limitations do not lead to fixed memory capacity limitations that are independent of the timing properties of an experiment. We show that interference can mimic both slot-like and continuous resource-like memory limitations, suggesting that these types of memory performance might not be as different as commonly believed. We speculate that slot-like WM limitations might arise from crowding-like phenomena in memory when participants have to retrieve items. Further, based on earlier research on parallel attention and enumeration, we suggest that crowding-like phenomena might be a common reason for the 3 major cognitive capacity limitations. As suggested by Miller (1956) and Cowan (2001), these capacity limitations might arise because of a common reason, even though they likely rely on distinct processes.
Mechanisms of Efficacy of CBT for Cambodian Refugees with PTSD: Improvement in Emotion Regulation and Orthostatic Blood Pressure Response

Based on the results of a randomized controlled trial, we examined a model of the mechanisms of efficacy of culturally adapted cognitive‐behavior therapy (CBT) for Cambodian refugees with pharmacology‐resistant posttraumatic stress disorder (PTSD) and comordid orthostatic panic attacks (PAs). Twelve patients were in the initial treatment condition, 12 in the delayed treatment condition. The patients randomized to CBT had much greater improvement than patients in the waitlist condition on all psychometric measures and on one physiological measure—the systolic blood pressure response to orthostasis (d = 1.31)—as evaluated by repeated‐measures MANOVA and planned contrasts. After receiving CBT, the Delayed Treatment Group improved on all measures, including the systolic blood pressure response to orthostasis. The CBT treatment's reduction of PTSD severity was significantly mediated by improvement in orthostatic panic and emotion regulation ability. The current study supports our model of the generation of PTSD in the Cambodian population, and suggests a key role of decreased vagal tone in the generation of orthostatic panic and PTSD in this population. It also suggests that vagal tone is involved in emotion regulation, and that both vagal tone and emotion regulation improve across treatment.
Improving Imaging Diagnosis of Persistent Nodal Metastases after Definitive Therapy for Oropharyngeal Carcinoma: Specific Signs for CT and Best Performance of Combined Criteria

BACKGROUND AND PURPOSE: Criteria for detection of persistent nodal metastases in treated oropharyngeal tumors are sensitive but nonspecific, leading to unnecessary nodal dissections. Developing specific imaging criteria for persistent nodal metastases could improve diagnosis while decreasing patient morbidity. MATERIALS AND METHODS: Patients with oropharyngeal squamous cell carcinoma with nodal metastases treated by definitive radiation therapy and subsequent nodal dissection were retrospectively evaluated. One hundred thirty-eight patients had pre- and posttherapy contrast-enhanced CTs evaluated by radiologists blinded to the status of pathologically proved hemineck persistent nodal metastases. Composite scoring criteria for CT, combined from individual parameters, were compared with radiologists' opinions, previous multiparameter criteria, and outcome data. RESULTS: New low-attenuation areas and a lack of size change (<20% cross sectional area) were both highly specific for persistent nodal metastases (99%; P = .0004). Extranodal disease on pretherapy imaging was moderately specific (86%; P = .001). The CSC correctly placed 29 patients in a low-risk category compared with 14 by previously reported criteria and radiologist reports. With good second-rater reliability, the CSC cutoff values stratified patients at highest risk of persistent nodal metastases, thereby improving specificity while maintaining sensitivity. CONCLUSIONS: Comparing pre- and posttherapy examinations improves specificity by discriminating focal findings and size change compared with a single time point. The CSC can categorize the risk of persistent nodal metastases more accurately than previous CT methods. This finding has the potential to improve resource use and reduce surgical morbidity.
Correlation of Ultrasonographic Parameters with Serum Creatinine in Chronic Kidney Disease

Objective: The purpose of our study is to correlate renal echogenicity with serum creatinine in order to determine the significance of renal echogenicity when it comes to identifying the progression of chronic kidney disease (CKD) and for the sonographic grading of CKD. Materials and Methods: Sixty patients above 30 years of age who had been diagnosed with CKD according to the guidelines of the National Kidney Foundation were included in the study. Patients on kidney replacement therapy or with fatty liver findings on ultrasonography were excluded. Ultrasounds of kidneys were performed by two radiologists who were blind to the patients’ serum creatinine levels. Renal cortical echogenicity was compared with serum creatinine. Statistical analysis was performed using one-way ANOVA followed by Scheffe's test. The relationship between serum creatinine and sonographic features was assessed by correlation coefficient analysis. A P value less than 0.05 was considered statistically significant. Results: Mean serum creatinine was 2.80 mg/dl for Grade 1 (range: 0.9-9.2 mg/dl), 3.69 mg/dl for Grade 2 (range: 1.2-10.3 mg/dl), 3.86 mg/dl for Grade 3 (range: 1.1-6.5 mg/dl), and 7.90 mg/dl for Grade 4 (range: 3.1-11.4 mg/dl). The grades being determined by cortical echogenicity on imaging A statistically significant, positive correlation was observed between serum creatinine and grading based on cortical echogenicity (P = 0.004). Conclusion: Renal echogenicity and its grading correlates better with serum creatinine in CKD than other sonographic parameters such as longitudinal size, parenchymal thickness, and cortical thickness. Hence, renal echogenicity is a better parameter than serum creatinine for estimating renal function in CKD, and has the added advantage of irreversibility.
QUR’AN MEMORIZERS AND INTERNET: STUDY AT MA’HAD KHOIR-UL-KAYYIS AND MA’HAD KUTUBUSSITTAH BABUSSALAM IN MAKASSAR

The Quran memorization is a highly recommended education in Islam. At the same time the internet has penetrated and become an irremovable part of all fields of human life, including santri life. Some are optimistic, but some are worried about the harm. The present study will discuss on how the internet utilized among Qur'an memorizers, and how it did affect to the achievement of each of them. It is different with the other scholars who have compared different groups of internet user and proposed contradictory conclusions. The surveys confirm that the Quran memorizers who have various techniques of memorizing, all aimed to utilize internet to increase the knowledge, but they are ultimately affected to use for social satisfactions and mere fun. Furthermore, the experiment has resulted that the increasing achievement has been performed during the internet banning, whereas the decrease happened at the access allowance.
Paleomagnetism and tectonics of the southern Atacama Desert (25–28°S), northern Chile

We report paleomagnetic results for 131 sites from the modern forearc of northern Chile (25°S and 28°S). Remanent magnetization in volcanic and intrusive rocks is mostly primary, while a secondary magnetization is observed in sedimentary rocks. Comparison of locality‐mean directions with expected paleomagnetic directions indicates vertical axis rotations from −7.3° ± 21.6° counterclockwise to 52.7° ± 17° clockwise. Jurassic to Early Cretaceous rocks from the Coastal Cordillera and Cretaceous to Paleocene rocks from the Central Depression show similar magnitude (>30°) clockwise rotations, while more variable rotations occur in Mesozoic to Eocene rocks of the Precordillera. Clockwise rotations in Mesozoic and Paleogene rocks occur in the Chilean Frontal Cordillera south of 27°30′S. Paleomagnetic results in three large Miocene ignimbrite sheets overlying rotated and nonrotated older rocks in the Precordillera and Pre‐Andean Depression which show no relative rotation between sites indicate that most rotations within the study area occurred prior to 18 Ma (early Miocene) and likely during and after the “Incaic” tectonic event, which affected large tracts of the central Andes. The postulated onset of rotations in the north Chilean forearc was contemporaneous with the beginning of horizontal shortening and uplift of the Eastern Cordillera in Bolivia and northwestern Argentina. Rotation of the Chilean forearc, enhancement of the curvature of the central Andes, and the formation of the Bolivian Orocline seem to be, for the most part, closely linked to the evolution of the Eocene‐Oligocene tectonics of the Eastern Cordillera.
Effect of postconditioning on infarct size in patients with ST elevation myocardial infarction

Background Small studies suggest that postconditioning reperfusion interrupted by brief repetitive cycles of reocclusions, may protect the myocardium in the clinical setting. Objective To test the hypothesis that postconditioning limits infarct size in relation to the area at risk in patients with ST elevation myocardial infarction (STEMI). Methods 76 patients (aged 37–87 years) eligible for primary percutaneous coronary intervention due to STEMI were randomised to standard percutaneous coronary intervention (n=38) or postconditioning, consisting of four cycles of 60 s reperfusion and 60 s of reocclusion before permanent reperfusion (n=38). Results The area at risk was determined from angiographic abnormally contracting segments. Infarct size was quantified from delayed enhancement MRI on days 6–9. Infarct size, expressed in relation to the area at risk, did not differ between the control group (44%; 30, 56) (median and quartiles) and the post-conditioned group (47%; 23, 63). The slope of the regression lines relating infarct size to the area at risk differed between the two groups. Infarct size was significantly (p=0.001) reduced by postconditioning in patients with large areas at risk. The area under the curve and peak troponin T release and CKMB during 48 h did not differ between patients in the control and postconditioning groups. Conclusions This prospective, randomised trial suggests that postconditioning does not reduce infarct size in patients with STEMI in the overall study group. The data indicate that postconditioning may be of value in patients with large areas at risk. Clinical trial registration information Karolinska Clinical Trial Registration (http://www.kctr.se). Unique identifier: CT20080014.
Beyond picture naming: norms and patient data for a verb-generation task.

PURPOSE In the current study, the authors aimed to (a) acquire a set of verb generation to picture norms; and (b) probe its utility as an outcomes measure in aphasia treatment. METHOD In Phase I, the verb-generation normative sample, 50 healthy volunteers generated verbs for 218 pictures of common objects (interstimulus interval = 5 s). In Phase II, 4 persons with aphasia (PWAs) generated verbs for 60 objects (interstimulus interval = 10 s). Their stimuli consisted of objects that were (a) recently trained (for object naming; n = 20), (b) untrained (a control set; n = 20), or (c) from a set of pictures named correctly at baseline (n = 20). Verb generation was acquired twice: once 2 months into and once following a 6-month home practice program. RESULTS No objects elicited perfect verb agreement in the normed sample. Stimuli with the highest percent agreement were mostly artifacts and dominant verbs primary functional associates. Although not targeted in treatment or home practice, PWAs mostly improved performance in verb generation postpractice. CONCLUSIONS A set of clinically and experimentally useful verb-generation norms was acquired for a subset of the Snodgrass and Vanderwart (1980) picture set. More cognitively demanding than confrontation naming, this task may help to fill the sizeable gap between object picture naming and propositional speech.
Positive End-expiratory Pressure Redistributes Regional Blood Flow and Ventilation Differently in Supine and Prone Humans

Background:Animal studies have demonstrated an interaction between posture and the effect of positive end-expiratory pressure (PEEP) on regional ventilation and lung blood flow. The aim of this study was to explore this interaction in humans. Methods:Regional lung blood flow and ventilation were compared between mechanical ventilation with and without PEEP in the supine and prone postures. Six normal subjects were studied in each posture. Regional lung blood flow was marked with 113mIn-labeled macroaggregates and ventilation with Technegas (99mTc). Radiotracer distributions were mapped using quantitative single-photon emission computed tomography. Results:In supine subjects, PEEP caused a similar redistribution of both ventilation and blood flow toward dependent (dorsal) lung regions, resulting in little change in the V/Q correlation. In contrast, in prone subjects, the redistribution toward dependent (ventral) regions was much greater for blood flow than for ventilation, causing increased V/Q mismatch. Without PEEP, the vertical ventilation-to-perfusion gradient was less in prone postures than in supine, but with PEEP, the gradient was similar. Conclusions:During mechanical ventilation of healthy volunteers, the addition of PEEP, 10 cm H2O, causes redistribution of both lung blood flow and ventilation, and the effect is different between the supine and prone postures. Our results suggest that the addition of PEEP in prone might be less beneficial than in supine and that optimal use of the prone posture requires reevaluation of the applied PEEP.
The mediation relationship of customer satisfaction between service quality and repurchase intention on e-commerce in Indonesia

This research aims to determine the relationship between service qualities and repurchase intention with customer satisfaction as the mediator variable on e-commerce in Indonesia. Data were obtained from 162 respondents by using close and self-administered types of questions. The respondents independently filled the given questionnaires with the Likert scale and Structural Equation Model (SEM) was used for analysis. The findings show that customer satisfaction variable is a mediation of web service quality and repurchase intention on e-commerce in Indonesia.
Age‐dependent alterations of the kynurenine pathway in the YAC128 mouse model of Huntington disease

Indoleamine 2,3 dioxygenase (Ido1), the first and rate‐limiting enzyme of the kynurenine pathway (KP), is a striatally enriched gene with increased expression levels in the YAC128 mouse model of Huntington disease (HD). Our objective in this study was to delineate age‐related KP alterations in this model. Three enzymes potentially catalyze the first step of the KP; Ido1 and Indoleamine 2,3 dioxygenase‐2 were highly expressed in the striatum and Tryptophan 2,3 dioxygenase (Tdo2) in the cerebellum. During development, Ido1 mRNA expression is dynamically regulated and chronically up‐regulated in YAC128 mice. Kynurenine (Kyn) to tryptophan (Trp) ratio, a measure of activity in the first step of the KP, was elevated in YAC128 striatum, but no change in Tdo2 mRNA levels or Kyn to Trp ratio was detected in the cerebellum. Ido1 induction was coincident with Trp depletion at 3 months and Kyn accumulation at 12 months of age in striatum. Changes in downstream KP metabolites of YAC128 mice generally followed a biphasic pattern with neurotoxic metabolites reduced at 3 months and increased at 12 months of age. Striatally specific induction of Ido1 and downstream KP alterations suggest involvement in HD pathogenesis, and should be taken into account in future therapeutic developments for HD.
Prevalencia da leptospirose em bovinos do Pantanal Mato-Grossense.

No Pantanal, a principal atividade economica e a pecuaria de corte, explorada de forma extensiva, em pastagens nativas, com baixa taxa de lotacao (3,6ha/ UA), onde predominam as fases de cria e recria em regime extensivo. O nivel tecnologico utilizado e baixo, compativel com uma atividade praticada de forma sustentada, praticada de acordo com as caracteristicas hidrologicas da regiao. Neste sistema, os animais recebem poucos cuidados e sao mantidos quase que exclusivamente em pastagens nativas em invernadas com poucas divisoes, de forma a otimizar o uso de aguadas (Cadavid Garcia, 1986; Almeida et al., 1996). A Leptospirose e uma doenca de distribuicao cosmopolita, sendo causada por diversas sorovariedades de Leptospira interrogans que infectam praticamente todas as especies animais, inclusive o homem. No Pantanal Mato-Grossense, as condicoes ecologicas sao altamente favoraveis a ocorrencia da Leptospirose Bovina, uma vez que o agente sobrevive mais tempo em areas alagadas e de temperaturas elevadas (Faine, 1982). A presenca da Leptospirose sp ja foi evidenciada em propriedade localizada na Nhecolandia com percentuais de 47% em matrizes e 61% em touros apresentando-se com o maior numero de reacoes para as sorovariedades hardjo e wolffi. Este trabalho teve por objetivo estimar a prevalencia de anticorpos anti-Leptospira interrogans em bovinos adultos do Pantanal Mato-Grossense. Foram sorteadas 28 propriedades, com area variando de 1.800 a 38.680 ha, pertencentes em sua maioria a sub-regiao da Nhecolandia e duas propriedades pertencentes, respectivamente as sub-regioes do Nabileque e Pocone (MT). O tamanho medio das propriedades foi de 17.688 ha e a mediana foi de 14.440 ha.