Miracle-dz/UniFAR-FTUs huggingface dataset:
Differential Expression of TFF1 and TFF3 in Patients Suffering from Chronic Rhinosinusitis with Nasal Polyposis

Trefoil family factor (TFF) proteins contribute to antimicrobial defense and the maintenance of sinonasal epithelial barrier integrity. Dysregulation of TFF expression may be involved in the development of chronic inflammation and tissue remodeling characteristically found in chronic rhinosinusitis with nasal polyposis (CRSwNP). Expressions of TFF1 and TFF3 were determined in specimens of middle nasal turbinate (MNT-0), bulla ethmoidalis (BE), and nasal polyps (NP) from CRSwNP patients (n = 29) and inferior nasal turbinate from a group of control patients (underwent nasal septoplasty, n = 25). An additional MNT sample was collected 6 months after functional endoscopic sinus surgery (FESS, MNT-6). TFF1 mRNA levels were significantly reduced in all specimens by approximately three- to five-fold, while TFF3 was increased in MNT-0, as compared with controls. Six months after surgery their levels were reversed to control values. CRSwNP patients with S. epidermidis isolated from sinus swabs showed upregulation of TFF3 in MNT and NP as compared with patients with sterile swabs. Target gene regulation was not affected by the presence of type 2 inflammation in patients with confirmed allergy. Results of this study imply participation of TFFs genes in the development of CRSwNP.
A thermal non-equilibrium model with Cattaneo effect for convection in a Brinkman porous layer

This paper aims to investigate the onset of thermal convection in a layer of fluid-saturated Brinkman porous medium taking into account fluid inertia and local thermal non-equilibrium (LTNE) between the solid and fluid phases with Cattaneo effect in the solid. A two-field model is used for the energy equations each representing the solid and fluid phases separately. The usual Fourier heat-transfer law is retained in the fluid phase while the solid phase is allowed to transfer heat via a Cattaneo heat flux theory. It is observed that the Cattaneo effect has a profound influence on the nature of convective instability. In contrast to the standard Brinkman convection with LTNE model, instability is found to occur through oscillatory convection depending on the value of solid thermal relaxation time parameter which in turn depends on other parametric values. The instability characteristics of the system are analyzed in detail for a wide range of parametric values including those for copper oxide and aluminium oxide solid skeletons.
Trigonometric osp(1|2) Gaudin model

The problems connected with Gaudin models are reviewed by analyzing model related to the trigonometric osp(1|2) classical r-matrix. The eigenvectors of the trigonometric osp(1|2) Gaudin Hamiltonians are found using explicitly constructed creation operators. The commutation relations between the creation operators and the generators of the trigonometric loop superalgebra are calculated. The coordinate representation of the Bethe states is presented. The relation between the Bethe vectors and solutions to the Knizhnik–Zamolodchikov equation yields the norm of the eigenvectors. The generalized Knizhnik–Zamolodchikov system is discussed both in the rational and in the trigonometric case.
Seawater 7 Li : a direct proxy for global CO 2 consumption by 1 continental silicate weathering ? 2

9 The fractionation of stable Li isotopes ( 6 Li, 7 Li) has become a promising proxy for 10 assessing changes related to continental silicate weathering patterns. Recently, the first complete 11 record of Cenozoic seawater Li isotopic composition ( 7 Li) was reported (Misra and Froelich, 12 2012, Science 335, 818-821) showing a stepwise increase of +9‰ over the last 56 Ma. This 13 increase was attributed to a general change in continental silicate weathering behavior caused by 14 tectonic uplift. In particular, the low global average riverine  7 Li inferred for the Paleocene15 Eocene boundary was explained by congruent silicate weathering of primary silicate minerals, 16 which is inconsistent with the stoichiometry of secondary minerals and the resultant water 17 chemistry. 18 In this study, we present a novel reactive transport modeling approach that explicitly 19 includes Li isotopic fractionation to assess alternative geochemically-constrained interpretations 20 that do not rely on congruent weathering. Simulations show that riverine  7 Li is mainly 21 controlled by the subsurface residence time, the corresponding weathering intensity, and the 22 *Manuscript Click here to download Manuscript: WannerEtAlRevision.doc Click here to view linked References s o u r c e : h t t p s : / / d o i . o r g / 1 0 . 7 8 9 2 / b o r i s . 7 4 3 9 8 | d o w n l o a d e d : 8 . 9 . 2 0 1 7
Nursing Students ' Tendency To Aggression and Relevant Factors

Methods: The population of our descriptive and cross-sectional study consists of 350 students studying at the department of nursing of a university in İstanbul. Sampling includes 236 students who are representative of the population, are 18 years or older, and were selected with the basic random sampling method. All volunteered to participate in the study. The data were obtained using the questionnaire form and the Aggression Scale, and the self-rating method was used to obtain data. Statistical data analysis was performed using chi-square test, MannWhitney U test and logistic regression analysis.
UNIQUENESS IN TRANSLATING ARABIC HAGIOGRAPHY OF SHAIKH ‘ABD AL-QĀDIR AL-JAILĀNĪ: THE CASE OF AN-NŪR AL-BURHĀNĪ

In Indonesia, the hagiographical book of Shaikh ʻAbd al-Qadir al-Jailani has many versions of translation. One of it is an-Nur al-burhani , a Javanese translation by Kyai Muslih al-Marāqi. Unlike other Javanese translations, an-Nur al-burhani is not merely a translation but can be considered a new book, in which the translator added some new information and opinion in it. Therefore, the book is interesting to be investigated deeply to find scientific information about the content of the book, the technique, method, and ideology of translation that are adopted and applied by the translator. Using content analysis, the study finds that the book consists of al-Jailani’s journey of life, his miracles and teachings. The other findings prove that the translator has implemented various techniques of translation such as calque, borrowing, description, amplification-addition, and adaptation techniques. The translator has tried to make the TT (Target Text) easy to be understood by Javanese people, but he tends to apply literal (linguistic transcodification) method rather than interpretative-communicative (translation of the sense) method. As a result, the TT is still influenced by the structure of Arabic as SL (Source Text) and not natural in everyday use of Javanese language. Thus, it can be inferred that the translator more dominantly adopts the ideology of foreignization than domestication. However, what the translator does is more advanced than the other Javanese translators, who usually use only the word for word or literal translation method. This is the uniqueness in translating al-Jailani’s hagiography or manaqib.
CLEP_A_206770 509..518

Anna Ponjoan 1–3 Josep Garre-Olmo 3 Jordi Blanch 1 Ester Fages 1,4 Lia Alves-Cabratosa 1 Ruth Martí-Lluch 1–3 Marc Comas-Cufí 1 Dídac Parramon 1,4 María García-Gil 1 Rafel Ramos 1,5 1Vascular Health Research Group (ISVGirona), Jordi Gol Institute for Primary Care Research (IDIAPJGol), Barcelona, Catalonia, Spain; 2Universitat Autònoma de Barcelona, Bellaterra, Catalonia, Spain; 3Girona Biomedical Research Institute (IDIBGI), Girona, Catalonia, Spain; 4Primary Care Services, Catalan Health Institute (ICS), Girona, Catalonia, Spain; 5Department of Medical Sciences, School of Medicine, Campus Salut, University of Girona, Girona, Catalonia, Spain Background: Electronic health records (EHR) from primary care are emerging in Alzheimer’s disease (AD) research, but their accuracy is a concern. We aimed to validate AD diagnoses from primary care using additional information provided by general practitioners (GPs), and a register of dementias. Patients and methods: This retrospective observational study obtained data from the System for the Development of Research in Primary Care (SIDIAP). Three algorithms combined International Statistical Classification of Diseases (ICD-10) and Anatomical Therapeutic Chemical codes to identify AD cases in SIDIAP. GPs evaluated dementia diagnoses by means of an online survey. We linked data from the Register of Dementias of Girona and from SIDIAP. We estimated the positive predictive value (PPV) and sensitivity and provided results stratified by age, sex and severity. Results: Using survey data from the GPs, PPV of AD diagnosis was 89.8% (95% CI: 84.7–94.9). Using the dataset linkage, PPV was 74.8 (95% CI: 73.1–76.4) for algorithm A1 (AD diagnoses), and 72.3 (95% CI: 70.7–73.9) for algorithm A3 (diagnosed or treated patients without previous conditions); sensitivity was 71.4 (95% CI: 69.6–73.0) and 83.3 (95% CI: 81.8–84.6) for algorithms A1 (AD diagnoses) and A3, respectively. Stratified results did not differ by age, but PPV and sensitivity estimates decreased amongst men and severe patients, respectively. Conclusions: PPV estimates differed depending on the gold standard. The development of algorithms integrating diagnoses and treatment of dementia improved the AD case ascertainment. PPV and sensitivity estimates were high and indicated that AD codes recorded in a large primary care database were sufficiently accurate for research purposes.
Efficiency of evolutionary algorithms in water network

The pipe sizing of water networks via evolutionary algorithms is of great interest because it allows the selection of alternative economical solutions that meet a set of design requirements. However, available evolutionary methods are numerous, and methodologies to compare the performance of these methods beyond obtaining a minimal solution for a given problem are currently lacking. A methodology to compare algorithms based on an efficiency rate (E) is presented here and applied to the pipe-sizing problem of four medium-sized benchmark networks (Hanoi, New York Tunnel, GoYang and R-9 Joao Pessoa). E numerically determines the performance of a given algorithm while also considering the quality of the obtained solution and the required computational effort. From the wide range of available evolutionary algorithms, four algorithms were selected to implement the methodology: a PseudoGenetic Algorithm (PGA), Particle Swarm Optimization (PSO), a Harmony Search and a modified Shuffled Frog Leaping Algorithm (SFLA). After more than 500,000 simulations, a statistical analysis was performed based on the specific parameters each algorithm requires to operate, and finally, E was analyzed for each network and algorithm. The efficiency measure indicated that PGA is the most efficient algorithm for problems of greater complexity and that HS is the most efficient algorithm for less complex problems. However, the main contribution of this work is that the proposed efficiency ratio provides a neutral strategy to compare optimization algorithms and may be useful in the future to select the most appropriate algorithm for different types of optimization problems.
Outsourcing FM Services in the Public Sector : A Review of 25 Years Research and Development

Design/methodology/approach: The article is based on literature reviews, case studies and personal experiences from practice for over 25 years, concentrating on the public sector. The article maintains an international focus on the FM development, with particular focus on the development in Norway and the Nordic countries. The knowledge development triangle, and its integration of education, research and practice, is used as an underlying theoretical framework.
Neighborhood deprivation and availability of culturally specific African-American and Latino fruits and vegetables in five small central Illinois cities

Introduction: Although individual-level dietary behavior among racial/ethnic minority groups in the US is influenced by cultural food preferences and socioeconomic position, few studies of the food store environment have simultaneously examined both factors. The objective of this cross-sectional study was to investigate the availability of culturally specific fruits and vegetables for African Americans and Latinos by levels of neighborhood deprivation. The 5 small central Illinois cities selected for the study have exhibited increasing numbers of both racial/ ethnic groups in the last decade. Methods: A validated audit tool was used to survey 118 food stores in 2008. Census 2000 block group data was used to create a neighborhood deprivation index (categorized as low, medium, and high) based on socioeconomic characteristics using principal component analysis. Statistical analyses were performed in SPSS version 17.0 to determine whether the availability of culturally specific fruits and vegetables (n = 31) varied by neighborhood levels of deprivation and store type. Results: Fewer than 50% of neighborhoods carried culturally specific fruits and vegetables, with the lowest availability found in low deprivation neighborhoods (p < 0.05). Culturally specific fruits and vegetables were most often found in neighborhoods with medium levels of deprivation, and in grocery stores (p < 0.05). Latino fruits and vegetables were less likely to be found across neighborhoods or in stores, compared to African-American fruits and vegetables. Conclusions: The limited availability of culturally specific fruits and vegetables for African Americans and Latinos highlights potential environmental challenges with adherence to daily dietary guidelines for fruit and vegetable consumption in these groups.
Secondhand smoke (SHS) exposure at home and at the workplace among non-smokers in Malaysia: Findings from the Global Adult Tobacco Survey 2011

INTRODUCTION Understanding the prevalence of secondhand smoke (SHS) exposure and the associated factors is beneficial for the formulation of effective measures to reduce exposure to SHS. The purpose of this study was to determine SHS exposure at home and workplace, and its associated factors among non-smoker Malaysian adults. METHODS Data were extracted from the Global Adult Tobacco Survey-Malaysia (GATS-M) that involved a representative sample of 5112 Malaysian adults. Logistic regression analyses were performed to examine the association between SHS exposure, sociodemographic factors, knowledge on the danger of SHS, and smoking restrictions at home and at work among non-smokers. RESULTS Among non-smoker Malaysians, age ≥15 years, 27.9% (equivalent to approximately 4.21 million non-smokers) and 33.9% (equivalent to approximately 1.37 million non-smokers) reported that they were exposed to SHS at home and the workplace, at least once a month, respectively. Women (AOR=2.12, 95% CI: 1.61–2.78), young individuals (AOR=3.06, 95% CI: 1.48–6.33), Malays (AOR=2.39, 95% CI: 1.56–3.64) or other Bumiputra ethnic groups (AOR=2.40, 95% CI: 1.39–4.19) and those who worked as other than government employees were more likely to report SHS exposure at home (non-government employee: AOR=1.88, 95% CI: 1.06–3.36). Respondents with a total smoking restriction at home did not report any SHS exposure at home. Similarly, those whose workplace had smoking restrictions were less likely to report SHS exposure at the work compared to their counterparts whose workplace had partial (AOR=3.08, 95% CI: 1.84–5.15) or no smoking restrictions (AOR=15.33, 95% CI: 6.75–34.86). CONCLUSIONS A substantial proportion of Malaysian adults were exposed to SHS at home and at work. The findings emphasize the need for policies on smoking restrictions at work and the need to promote the adoption of a completely smoke-free home, among the Malaysian population.
How specific is apprenticeship training? Evidence from inter-firm and occupational mobility after graduation

Do apprenticeships convey mainly general or also firm- and occupation-specific human capital? Specific human capital may allow for specialization gains, but may also lead to allocative inefficiency due to mobility barriers. We analyse the case of Switzerland, which combines a comprehensive, high-quality apprenticeship system with a lightly regulated labour market. To assess human capital transferability after standardized firm-based apprenticeship training, we analyse inter-firm and occupational mobility and their effects on post-training wages. Using a longitudinal data set based on the PISA 2000 survey, we find high inter-firm and low occupational mobility within one year after graduation. Accounting for endogenous changes, we find a negative effect of occupation changes on wages, but no significant wage effect for firm changes. This indicates that occupation-specific human capital is an important component of apprenticeship training and that skills are highly transferable within an occupational field.
Atorvastatin Increases HDL Cholesterol by Reducing Cholesteryl Ester Transfer Protein

Netherlands Organization for Applied Scientifi c Research-Quality of Life, Gaubius Laboratory, P.O. Box 2215, 2301 CE Leiden, The Netherlands; Departments of General Internal Medicine, Endocrinology, and Metabolic Diseases, and Cardiology, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands; Leiden/Amsterdam Center for Drug Research, Div. Biopharmaceutics, P.O. box 9502, 2300 RA Leiden, The Netherlands; Department of Internal Medicine, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands.
What difference do beliefs make? Gender job associations and work climate

This paper investigates how women and men value their work climate if performing jobs with stereotypical male or female tasks. Using a special variable from a big data set we are able to address whether tasks or jobs are considered as more appropriate for males or females by society. We find that women report lower satisfaction with their work climate if performing jobs with stereotypical male tasks and vice versa. We argue that our results are in line with a recent study of Akerlof and Kranton (2000) considering identity based utility outcomes. The results indicate that the work climate might lead to gender specific utility outcomes and trade-off decisions. Thus, the results might help to enlarge the understanding of occupational segregation by gender. We apply a simultaneous equation model to model the selection into the job alongside our ordered probit model for work climate to cope with the endogeneity of the job choice.
Tourism and Economic Growth: African Evidence from Panel Vector Autoregressive Framework

Using a panel vector autoregressive model this paper investigates the dynamic and endogeneous contribution of tourism to output based on a sample of 40 African countries for the period 1990-2006. Results from the study confirm tourism to be an important ingredient of African development although private investment, openness, and human capital remain the main drivers. Further analysis reveals the existence of a reverse causation from national income to tourism development, thus confirming both tourism-led economic development and economic-driven tourism growth.
Conditions and constraints of political participation among Turkish students in Germany

Abstract What motivates conventional and unconventional participation in the political realm? Specifically, what are the facilitators and constraints of political participation in the views of Turkish migrants? The present study explored these conditions using semi-structured interviews with a small number of university students of Turkish descent in Germany, as these may be more likely to become spokespersons of the Turkish people in Germany than other members of their ethnic minority in-group. The interviewees draw attention to characteristics of different kinds of political activities, linking them to a lack of trustworthiness, frustration, disappointment, and reflection. Most of these factors can be related to rational actor approaches of political behavior; hence, the findings are discussed with respect to rational choice theory and with regard to the importance of sociopolitical and emotional integration of Turkish migrants. The role of political trust is discussed as that of a potential moderating force in the facilitation of political participation.
Corporate Philanthropy, Research Networks, and Collaborative Innovation

Using a unique dataset of corporate philanthropy, we find that direct giving activities are positively associated with more collaborative and original innovation. In contrast, our results do not hold for corporate foundations’ contributions. Our results suggest that much of what is ostensibly promoted as philanthropy actually reflects research-related networking activities. The effect of direct giving on innovation is more pronounced in more opaque firms and more innovative and competitive industries. These findings provide evidence of the distinct motives by which firms choose between direct giving and foundation giving. This study suggests that firms can use direct philanthropy to expand firm-boundaries by developing innovation with research partners.
Characterization of 20 complete plastomes from the tribe Laureae (Lauraceae) and distribution of small inversions

Lindera Thunb. (Lauraceae) consists of approximately 100 species, mainly distributed in the temperate and tropical regions of East Asia. In this study, we report 20 new, complete plastome sequences including 17 Lindera species and three related species, Actinodaphne lancifolia, Litsea japonica and Sassafras tzumu. The complete plastomes of Lindera range from 152,502 bp (L. neesiana) to 154,314 bp (L. erythrocarpa) in length. Eleven small inversion (SI) sites are documented among the plastomes. Six of the 11 SI sites are newly reported and they locate in rpoB-trnC, psbC-trnS, petA-psbJ, rpoA and ycf2 regions. The distribution patterns of SIs are useful for species identification. An average of 83 simple sequence repeats (SSRs) were detected in each plastome. The mono-SSRs accounted for 72.7% of total SSRs, followed by di- (12.4%), tetra- (9.4%), tri- (4.2%), and penta-SSRs (1.3%). Of these SSRs, 64.6% were distributed in an intergenic spacer (IGS) region. In addition, 79.8% of the SSRs are located in a large single copy (LSC) region. In contrast, almost no SSRs are distributed in inverted repeat (IR) regions. The SSR loci are useful to identifying species but the phylogenetic value is low because the majority of them show autapomorphic status or highly homoplastic characteristics. The nucleotide diversity (Pi) values also indicated the conserved nature of the IR region compared to LSC and small single copy (SSC) regions. Five spacer regions with high Pi values, trnH-psbA, petA-psbJ and ndhF-rpl32, rpl32-trnL and Ψycf1-ndhF, have a potential use for the molecular identification study of Lindera and related species. Lindera species form a paraphyletic group in the plastome tree because of the inclusion of related genera such as Actinodaphne, Laurus, Litsea and Neolitsea. A former member of tribe Laureae, Sassafras, forms a clade with the tribe Cinnamomeae. The SIs do not affect the phylogenetic relationship of Laureae. This result indicated that ancient plastome captures may have contribute to the mixed intergeneric relationship of Laureae. Alternatively, the result may indicate that the morphological characters defined the genera of Lauraceae originated for several times.