Miracle-dz/UniFAR-FTUs huggingface dataset:
The Effects of the Gaelic Athletic Association 15 Training Program on Neuromuscular Outcomes in Gaelic Football and Hurling Players: A Randomized Cluster Trial

Abstract O'Malley, E, Murphy, JC, McCarthy Persson, U, Gissane, C, and Blake, C. The effects of the Gaelic Athletic Association 15 training program on neuromuscular outcomes in Gaelic football and hurling players: A randomized cluster trial. J Strength Cond Res 31(8): 2119–2130, 2017—Team-based neuromuscular training programs for injury prevention have been tested primarily in female and adolescent athletes in soccer, handball, and basketball with limited research in adult male field sports. This study explored whether the GAA 15, a multifaceted 8-week neuromuscular training program developed by the Gaelic Athletic Association (GAA), could improve risk factors for lower limb injury in male Gaelic footballers and hurlers. Four Gaelic sports collegiate teams were randomized into intervention or control groups. Two teams (n = 41), one football and one hurling, were allocated to the intervention, undertaking a 15 minutes program of neuromuscular training exercises at the start of team training sessions, twice weekly for 8 weeks. Two matched teams (n = 37) acted as controls, participating in usual team training. Lower extremity stability (Y-Balance test [YBT]) and jump-landing technique using the Landing Error Scoring System (LESS) were assessed preintervention and postintervention. There were moderate effect sizes in favor of the intervention for right (d = 0.59) and left (d = 0.69) composite YBT scores, with adjusted mean differences between intervention and control of 3.85 ± 0.91% and 4.34 ± 0.92% for right and left legs, respectively (p < 0.001). There was a greater reduction in the mean LESS score in favor of the intervention group after exercise training (Cohen's d = 0.72, adjusted mean difference 2.49 ± 0.54, p < 0.001). Clinically and statistically significant improvements in dynamic balance and jump-landing technique occurred in collegiate level Gaelic football and hurling players who adopted the GAA 15, when compared with usual training. These findings support application and evaluation of the GAA 15 in other player groups within the Gaelic games playing population.
Dual-energy CT for characterization of the incidental adrenal mass: preliminary observations.

OBJECTIVE The purpose of our study was to evaluate the accuracy of virtual unenhanced images reconstructed from contrast-enhanced dual-energy CT for the differentiation of incidental adrenal masses in comparison with standard unenhanced CT. MATERIALS AND METHODS One hundred-forty patients (mean age, 74±9 years) underwent unenhanced and contrast-enhanced CT of the abdomen, the latter acquired with dual-energy for reconstruction of virtual unenhanced images. Two blinded and independent readers (R1 and R2) measured attenuation of each incidental adrenal mass on standard unenhanced and virtual unenhanced images using an optimized dual-energy three-material decomposition algorithm. RESULTS Fifty-one incidental adrenal masses were found in 42 of 135 patients (31%); 39 incidental adrenal masses were ≥1 cm. On the basis of unenhanced CT, 29 of 51 incidental adrenal masses and 22 of 39 incidental adrenal masses≥1 cm were classified as benign (HU<10). Virtual unenhanced image quality was rated as good or with mild impairment (2.45±0.83 for R1, 2.45±0.99 for R2). Image noise was 12.7±3.6 HU in unenhanced images and 8.8±2.0 HU in virtual unenhanced images (p<0.001). There was no significant difference in incidental adrenal mass attenuation between unenhanced and virtual unenhanced images for all incidental adrenal masses (5.9±21.0 HU vs 7.0±20.6 HU, p=0.48) and for those≥1 cm (6.6±18.5 HU vs 7.9±18.3 HU, p=0.87). Sensitivity, specificity, and accuracy of virtual unenhanced images for the characterization of incidental adrenal masses as probably benign were 76%, 82%, and 78% for R1 and 79%, 95%, and 86% for R2, respectively. For incidental adrenal masses≥1 cm, sensitivity, specificity, and accuracy increased to 95%, 100%, and 97% for R1 and 91%, 100%, and 95% for R2. CONCLUSION Reconstruction of virtual unenhanced images from contrast-enhanced dual-energy CT of the abdomen allows the characterization of the incidental adrenal masses with a good accuracy compared with standard unenhanced CT, with the most favorable results in incidental adrenal masses measuring≥1 cm.
Myocardial Metabolism Under Control of a Cytokine Receptor

In recent years, the heart has been rediscovered under the lenses of immunology. Immune cells and immune mediators have been widely reported to influence the heart under a wide range of physiological and pathological conditions, such as healing after myocardial infarction,[1][1], [2][2], [3][3]
On Risks and Side Effects: Does Creative Accomplishment Make us Narcissistic?

Abstract Kaufman (2018) calls for a research agenda on outcomes of creativity. Despite its many conceivable positive consequences, we focus on narcissism as a potentially less socially desirable outcome of creative accomplishment in this commentary. Evidence from cross-sectional studies suggests a systematic link between different indicators of creativity and narcissism. We argue that - irrespective of methodological challenges associated with this research - it seems indeed plausible that creativity is associated with narcissism. The link is presumably strongest in individuals who engage in creativity for recognition motives. Narcissistic strivings might ignite creative endeavors, and positive social feedback for creative accomplishments might fuel narcissism. While more research needs to be done to understand the causal nature of the effects, the available evidence points to narcissism as a socially undesirable aspect of creativity which is not commonly discussed.
Changing policy focus through organizational reform? The case of the pharmaceutical unit in the European Commission

This article contributes to the debate on the significance of organizational structure for administrative decision behaviour by exploring the effects of a reorganization in the European Commission. It is shown that the move of the pharmaceutical unit from DG Enterprise to DG SANCO impacted on the process of developing a regulatory framework on information to patients. After the reorganization, the focus of the policy process changed from industry to public health and other action alternatives became salient, which eventually led to changes in the policy outcome. The article demonstrates how horizontal specialization systematically tips the scales in the direction of certain actors, solutions, interests and concerns in decision processes, eventually resulting in a change of policy focus. The gap between organizational structure and administrative decision behaviour is thus not as large as is often assumed in the literature.
Coronary angiographic characteristics of patients with permanent artificial pacemakers.

BACKGROUND The cause of severe cardiac conduction disturbances is often uncertain. The aim of this study was to examine a group of patients with permanent pacemakers who underwent coronary arteriography to determine the extent of coronary atherosclerotic disease that might be responsible for the conduction disturbances. METHODS AND RESULTS Forty-three consecutive patients with a permanent pacemaker and 36 matched control patients were investigated. The coronary angiographic study included measurement of diameter and stenosis severity, qualitative assessment of flow, and classification of pathological anatomy, particularly the blood supply to territories supplying the different segments of the conduction system. Among 43 patients with a permanent pacemaker, 27 had ischemic heart disease (17 after coronary artery bypass graft surgery). The conduction disturbance was infranodal in 28 patients, sinus nodal in 6, AV nodal in 4, and complete AV block of unspecified origin in 5. Patients with permanent pacemakers had a coronary artery pathology compromising blood flow to the septal branches and the right coronary artery (type IV anatomy). This pattern was significantly different from the matched control patients, in whom the most prevalent coronary anatomy was the combination of right coronary artery with distal left anterior descending artery (not involving the septal branches) lesions (P=.007). CONCLUSIONS Patients with coronary artery disease and severe conduction disturbances that require implantation of permanent pacemakers are more likely to have a specific pathological coronary anatomy that combines a compromised blood flow to the septal branches of the left anterior descending artery with right coronary artery lesions. The location of lesions in the coronary tree rather than severe diffuse atherosclerosis appears to be responsible for the conduction disturbances.
Multiple Axis-II Diagnoses of Personality Disorder

Background Simultaneous diagnosis of more than one personality disorder (PD) has been termed ‘comorbidity’ or ‘co-occurrence’ implying that single diagnoses are the norm and multiple diagnoses interesting exceptions. Surveys of PD subjects in fact show 1.5–5.6 diagnoses per subject. Our study explores the hypothesis that multiple PD diagnosis is common and increases with increasingly personality disordered populations. Method The PDQ–R questionnaire was administered to three UK samples: referrals for specialist PD in-patient treatment (n = 275); high tariff offenders attending a probation centre (n = 57); and undergraduate students (n = 274). Results Means of 6.0 (95% CI 5.7–6.3), 4.0 (3. 1–5.0) and 3.4 (3.0–3.8) PDQ–R diagnoses per subject were found respectively. High rates of PD diagnosis in individual subjects suggest that multiple diagnosis is the norm rather than the exception. Conclusions Multiple diagnosis of PD is better construed as ‘breadth’ of psychopathology rather than comorbidity and is a function of sampling frame. High rates of multiple diagnoses question the interpretation of studies of any single PD. The graded construct of ‘breadth’ of axis–II pathology may further our understanding of PD.
Burdened by Proof: How the Australian Refugee Review Tribunal has Failed Lesbian and Gay Asylum Seekers

Our argument in this paper is that the evidentiary practices and procedures that have been developed by the Australian Refugee Review Tribunal are operating at a routinely low standard. Such practices contribute to decisions that are manifestly unfair and potentially wrong in law. Our conclusions are drawn from our detailed study of more than 300 refugee tribunal decisions made in Canada and Australia in response to asylum claims brought by lesbians and gay men.
The Current State of Corporate Social Responsibility Behavior in National Collegiate Athletic Association Division-I Athletic Departments

National Collegiate Athletic Association (NCAA) Division I athletic departments are generating revenue that would place them in comparison with Forbes100 “Best Small Business” list (Badenhausen, 2014). Corporate Social Responsibility (CSR) is the main issue that is investigated in this paper as it pertains to the actions of the Division I athletic departments. The Division I athletic departments are at the highest level in collegiate athletics based on the ability to offer more athletic scholarships to student athletes. CSR is the belief that a company should be a good citizen in society (Bowen, 2013). The paper will take a global perspective view of the CSR actions of athletic departments through a content analysis of the department’s websites for the constructs: environmental sustainability, cause related marketing, and community service. The paper serves as means for understanding if athletic departments are conducting CSR, and is the first timea content analysishas been applied to the investigation of CSR actions. The paper submits that NCAA Division I athletic departments are taking CSR actions in support of the three constructs researched.
Pharmacokinetics of colistin in chickens at different ages

A. HARITOVA, L. LASHEV & I. KANELOV Department of Pharmacology, Toxicology and General Therapeutics, Faculty of Veterinary Medicine,Trakia University, Stara Zagora; Bulgaria Colistin is a decapeptide antibiotic with a narrow spectrum of antibacterial activity mainly against Gram-negative microor-ganisms (Ziv,1981). It is also able to inac-tivate bacterial toxins
Supporting opportunities for female entrepreneurs in Jordan

Female entrepreneurship in developing countries is a growing body of research that tries to address the main challenges faced in such a context. The aim of this paper is to shed some light on the real opportunities for female entrepreneurs in terms of support for their start-ups. A lack of studies with this specific focus may detach the pertinent literature from real business practice and the true conditions faced by women during the start-up process. We grounded our analysis in Jordan, a country that has received little attention, despite the fact that it has one of the liveliest entrepreneurial contexts in the Middle East. A sample of 28 institutions operating in Jordan that offer support for entrepreneurial activities were examined. This is followed by a discussion of the main implications of the initiatives dedicated to female entrepreneurs.
Older Persons' Perceptions of the Frequency and Meaning of Elderspeak from Family, Friends, and Service Workers

Older persons (N = 159) were surveyed for their impressions of and experiences with elderspeak from friends, same-age family members, younger family members, familiar service workers, and unfamiliar service workers. Two dimensions, “warmth” and “superiority,” emerged in the judgments of elderspeak from all five speaker types. Respondents perceived more warmth and less superiority in elderspeak from friends than they did in elderspeak from unfamiliar service workers. Among younger seniors, elderspeak was received primarily from unfamiliar service workers, whereas among nursing home residents, elderspeak was received from all speaker types. Variation thus exists in the covert experiences of elderspeak from different sources, and in the frequency of receipt of elderspeak from different sources.
Evaluation of a Ventricular Assist Device: Stability Under X-Rays and Therapeutic Beam Attenuation

Improved outcomes and quality of life of heart failure patients have been reported with the use of left ventricular assist devices (LVADs). However, little information exists regarding devices in patients undergoing radiation cancer treatment. Two HeartWare Ventricular Assist Device (HVAD) pumps were repeatedly irradiated with high intensity 18 MV x-rays to a dosage range of 64–75 Gy at a rate of 6 Gy/min from a radiation oncology particle accelerator to determine operational stability. Pump parameter data was collected through a data acquisition system. Second, a computerized tomography (CT) scan was taken of the device, and a treatment planning computer estimated characteristics of dose scattering and attenuation. Results were then compared with actual radiation measurements. The devices exhibited no changes in pump operation during the procedure, though the titanium components of the HVAD markedly attenuate the therapy beam. Computer modeling indicated an 11.8% dose change in the absorbed dosage that was distinctly less than the 84% dose change measured with detectors. Simulated and measured scattering processes were negligible. Computer modeling underestimates pretreatment dose to patients when the device is in the field of radiation. Future x-ray radiation dosimetry and treatment planning in HVAD patients should be carefully managed by radiation oncology specialists.
Evaluation of Convection-Permitting Precipitation Forecast Products Using WRF, NMMB, and FV3 for the 2016–17 NOAA Hydrometeorology Testbed Flash Flood and Intense Rainfall Experiments

During the summers of 2016 and 2017, the Center for Analysis and Prediction of Storms (CAPS) ran real-time storm-scale ensemble forecasts (SSEFs) in support of the Hydrometeorology Testbed (HMT) Flash Flood and Intense Rainfall (FFaIR) experiment. These forecasts, using WRF-ARW and Nonhydrostatic Mesoscale Model on the B-grid (NMMB) in 2016, and WRF-ARW and GFDL Finite Volume Cubed-Sphere Dynamical Core (FV3) in 2017, covered the contiguous United States at 3-km horizontal grid spacing, and supported the generation and evaluation of precipitation forecast products, including ensemble probabilistic products. Forecasts of 3-h precipitation accumulation are evaluated. Overall, the SSEF produces skillful 3-h accumulated precipitation forecasts, with ARW members generally outperforming NMMB members and the single FV3 member run in 2017 outperforming ARW members; these differences are significant at some forecast hours. Statistically significant differences exist in the performance, in terms of bias and ETS, among subensembles of members sharing common microphysics and PBL schemes. Year-to-year consistency is higher for PBL subensembles than for microphysical subensembles. Probability-matched (PM) ensemble mean forecasts outperform individual members, while the simple ensemble mean exhibits substantial bias. A newly developed localized probability-matched (LPM) ensemble mean product was produced in 2017; compared to the simple ensemble mean and the conventional PM mean, the LPM mean exhibits improved retention of small-scale structures, evident in both 2D forecast fields and variance spectra. Probabilistic forecasts of precipitation exceeding flash flood guidance (FFG) or thresholds associated with recurrence intervals (RI) ranging from 10 to 100 years show utility in predicting regions of flooding threat, but generally overpredict the occurrence of such events; however, they may still be useful in subjective flash flood risk assessment.
Deconstructing calsequestrin. Complex buffering in the calcium store of skeletal muscle

Since its discovery in 1971, calsequestrin has been recognized as the main Ca2+ binding protein inside the sarcoplasmic reticulum (SR), the organelle that stores and upon demand mobilizes Ca2+ for contractile activation of muscle. This article reviews the potential roles of calsequestrin in excitation–contraction coupling of skeletal muscle. It first considers the quantitative demands for a structure that binds Ca2+ inside the SR in view of the amounts of the ion that must be mobilized to elicit muscle contraction. It briefly discusses existing evidence, largely gathered in cardiac muscle, of two roles for calsequestrin: as Ca2+ reservoir and as modulator of the activity of Ca2+ release channels, and then considers the results of an incipient body of work that manipulates the cellular endowment of calsequestrin. The observations include evidence that both the Ca2+ buffering capacity of calsequestrin in solution and that of the SR in intact cells decay as the free Ca2+ concentration is lowered. Together with puzzling observations of increase of Ca2+ inside the SR, in cells or vesicular fractions, upon activation of Ca2+ release, this is interpreted as evidence that the Ca2+ buffering in the SR is non‐linear, and is optimized for support of Ca2+ release at the physiological levels of SR Ca2+ concentration. Such non‐linearity of buffering is qualitatively explained by a speculation that puts together ideas first proposed by others. The speculation pictures calsequestrin polymers as ‘wires’ that both bind Ca2+ and efficiently deliver it near the release channels. In spite of the kinetic changes, the functional studies reveal that cells devoid of calsequestrin are still capable of releasing large amounts of Ca2+ into the myoplasm, consistent with the long term viability and apparent good health of mice engineered for calsequestrin ablation. The experiments therefore suggest that other molecules are capable of providing sites for reversible binding of large amounts of Ca2+ inside the sarcoplasmic reticulum.
Reduced foetal growth and growth hormone secretion in adult life

Recent studies suggest that growth restriction or other adverse influences acting in utero or during early infancy lead to permanent alterations in growth hormone (GH) secretion. As GH secretion is known to predict cardiovascular risk, alterations in GH may contribute to the association between reduced foetal growth and cardiovascular disease. We have therefore assessed the relationship between birth size and GH secretion in a prospective study of young adults whose birth size was recorded and who have had their current blood pressure and glucose tolerance measured.
Is This the Curriculum We Want? Doctoral Requirements and Offerings in Methods and Methodology

A political scientists what it is they study and you will get a range of answers reflecting the breadth of research communities affiliated with the discipline. (As of 2002 the APSA has 36 organized sections and 50 related groups.) For a variety of purposes, the fact that we share little more than an institutional label may not matter much; but for the purpose of doctoral education, this very institutional label forces us to grapple with what we have in common. The years devoted to doctoral education represent the key point of socialization to the academy at large, and the profession in particular, and program-wide doctoral requirements enact departments’ judgments about what constitutes a “political scientist” above and beyond the substantive fields of American politics, comparative politics, international relations, and political theory. What are these requirements? In this paper, I report aggregate statistics on doctoral program requirements and offerings based on my extended study of 57 doctoral programs in the United States (Schwartz-Shea 2001). For each department, three sets of questions guided the investigation: (1) Are there any program-wide requirements? Or, are requirements decided by each field? (2) What are the curricular definitions of “methods” and “methodology? ” That is, are “methods” courses exclusively quantitative or are courses in “qualitative” methodology offered or required as well? (3) To what extent are philosophy of science and the scope and/or history of the discipline offered or required at the doctoral level? This evidence base provides a starting point for addressing the title of the paper: Is this the curriculum we want? More specifically, to what extent is there a core to the discipline of political science that is transmitted to its future scholars? Does this core transmit what is most important or most central to the discipline? Does this required core, as well as the additional offerings in methods and methodology, prepare future scholars to understand the range of approaches that members of the discipline find important for the study of politics? In what follows, I first describe the data and methodology of the study, offer background relevant by Peregrine Schwartz-Shea, University of Utah to understanding curricular choices, and then present the aggregate statistics. In the final sections, I discuss the findings and then offer an argument for methodological pluralism inclusive of qualitative research based on an interpretive epistemology.
Variable density incoherent spatiotemporal acquisition (VISTA) for highly accelerated cardiac MRI

For the application of compressive sensing to parallel MRI, Poisson disk sampling (PDS) has been shown to generate superior results compared with random sampling methods. However, due to its limited flexibility to incorporate additional constraints, PDS is not readily extendible to dynamic applications. Here, we propose and validate a pseudo‐random sampling technique that allows incorporating constraints specific to dynamic imaging.