Miracle-dz/UniFAR-FTUs huggingface dataset:
Gr upSM Ocular Involvement in Multiple Sclerosis

Ocular involvement in patients with multiple sclerosis may be observed as acute or chronic optic neuritis, anterior uveitis, intermediate uveitis, colour vision abnormalities, macular edema, etc. Acute optic neuritis is possibly the most common manifestation. Acute optic neuritis presents as visual loss generally associated with pain with ocular movements. Systemic corticosteroid use shortens the duration of attacks. The patients may have multiple optic neuritis attacks during the course of the disease. Some patients may have fluctuating vision with subclinical disease activity. Subclinical disease activity may be diagnosed with pattern visual evoked potential testing. Colour vision tests, magnetic resonance imaging, ocular electrophysiology and optical coherence tomography are generally used in clinical settings in the diagnosis and follow-up of the disease activity. Fatih C Gundogan1*, Salih Uzun2, Önder Ayyıldız1 and Gokhan Ozge1 1Gulhane Military Medical Academy, Ophthalmology, Turkey 2Etimesgut Military Hospital, Ophthalmology, Turkey *Corresponding author: Fatih C Gundogan, GATA Medical School, Department of Ophthalmology, Ankara, Turkey, Email: fgundogan@yahoo.com Published Date: May 10, 2016
EFFECTS OF VESICULAR-ARBUSCULAR MYCORRHIZA ON 14C AND 15N DISTRIBUTION IN NODULATED FABABEANS

A two-compartment growth chamber in which the aboveground plant materials were exposed to 14CO2 and the belowground portion was exposed to 15N2 under normal atmospheric pressure was designed for carbon and nitrogen transfer studies. Vicia faba infected with vesicular-arbuscular fungus Glomus mossae and non-mycorrhizal plants fixed similar quantities of N2 at an age of 6½ wk. Approximately 0.10 mg N was fixed∙g−1 dry plant materials∙day−1 and 40 mg C∙g−1 dry matter day−1 were synthesized by mycorrhizal and non-mycorrhizal fababeans during 48 h exposure to 14CO2 at 6½ wk with no apparent difference in yield of dry matter. The non-mycorrhizal plants transferred 37% of the fixed 14C beneath ground. The mycorrhizal ones transferred 47% of the fixed 14C beneath ground. Most of the difference could be accounted for in the belowground respiration. The 14CO2 produced by root-microbial systems of the mycorrhizal fababeans was twice as great as that of the nonmycorrhizal; both contained active rhizobium.
The role of gender and other socio-economic factors in the adoption of the contagious bovine pleuropneumonia (CBPP) vaccine

The International Livestock Research Institute (ILRI) works to improve food security and reduce poverty in developing countries through research for better and more sustainable use of livestock. ILRI is a member of the CGIAR Consortium, a global research partnership of 15 centres working with many partners for a food-secure future. ILRI has two main campuses in East Africa and other hubs in East, West and Southern Africa and South, Southeast and East Asia. ilri.org
Neuroprotective role of dexmedetomidine pretreatment in cerebral ischemia injury via ADRA2A-mediated phosphorylation of ERK1/2 in adult rats

Neuroprotective effects of dexmedetomidine (Dex) have been reported in various models of brain injury. However, to our knowledge, the neuroprotective mechanism of Dex pretreatment in rats remains unknown. The aim of the present study was to detect the expression of the α2A adrenergic receptor (ADRA2A) in focal ischemic brain tissues and to investigate the protective role and corresponding mechanism of Dex pretreatment in cerebral ischemia in rats. A hypoxia/reoxygenation (H/R) cell model in primary cultured astrocytes and a focal cerebral ischemia/reperfusion (I/R) model in adult rats were used. The expression of ADRA2A and extracellular signal-regulated kinases 1 and 2 (ERK1/2) in the primary cultured astrocytes and rat brain ischemic tissues was detected in the different conditions prior to and following Dex pretreatment using western blotting. The H/R model of primary cultured astrocytes and the focal cerebral I/R model in adult rats were successfully constructed. Under the normal oxygen conditions, 500 ng/ml Dex pretreatment increased the expression of ADRA2A and phosphorylated (p)-ERK1/2 in the astrocytes compared with in the control group. Hypoxic culture for 6 h and then reoxygenation for 24 h decreased the levels of p-ERK1/2 in the astrocytes compared with those in control group. This decrease was prevented by Dex pretreatment for 3 h. The hypoxic culture and then reoxygenation increased the expression of ADRA2A. Similarly, compared with those prior to Dex treatment, the levels of ADRA2A and p-ERK1/2 in the brain ischemic tissues following Dex treatment were increased. The levels of ADRA2A and p-ERK1/2 were 0.72±0.23 and 0.66±0.25 following Dex treatment, compared with 0.76±0.22 and 0.31±0.18, respectively, prior to Dex treatment. The effect of Dex pretreatment increasing p-ERK1/2 expression was attenuated by AG1478 pretreatment. In summary, Dex appeared to promote phosphorylation of ERK1/2 in astrocytes under H/R. As a specific agonist of ADRA2A, Dex may activate phosphorylation of ERK1/2 via ADRA2A in astrocytes. Thus, the neuroprotective role of Dex pretreatment against cerebral ischemic injury may function via ADRA2A-mediated phosphorylation of ERK1/2.
Real Exchange Rate Misalignment: An Application of Behavioral Equilibrium Exchange Rate (BEER) to Nigeria

This paper seeks to estimate the long run behavioral equilibrium exchange rate in Nigeria. The empirical analysis builds on quarterly data from 1986Q1 to 2006Q4 and derives a Behavioral Equilibrium Exchange Rate (BEER) and a Permanent Equilibrium Exchange Rate (PEER). The econometric analysis starts by analyzing the stochastic properties of the data and found all the variables stationary at first level of differencing. Accordingly, the paper proceeds by estimating vector-error correction models. Regression results show that most of the long-run behavior of the real exchange rate could be explained by real net foreign assets, terms of trade, index of crude oil volatility, index of monetary policy performance and government fiscal stance. On the basis of these fundamentals, four episodes each of overvaluation and undervaluation were identified and the antecedents characterizing the episodes were equally traced to the archive of exchange rate management in the country within the review period. Among others for instance, large inflow of oil revenues into the country and stable macroeconomic performance were discovered to account for undervaluation of the real exchange rate between 2001Q1 and 2006Q4 in Nigeria. The results further suggest that deviations from the equilibrium path are eliminated within one to two years. The paper recommends the pursuance of sound monetary policy as an instrument for achieving real exchange rate cum macroeconomic stability in Nigeria.
Identification of Effects of Dynamic Treatments with a Difference-in-Differences Approach

This paper examines the power of a conditional difference-in-differences approach to nonparametrically identify the causal effects of sequences of interventions. In the classical difference-in-differences case, a period previous to the implementation of the intervention is used as a comparison period to get rid of common trends for treated and nontreated. When sequences of programs are studied, two different utilizations of the available information are possible to construct the comparison period. The first one only uses the information available in the period previous to the first possible intervention. The second one uses the information sequentially. Here, we use the information available between the interventions in addition to the period previous to the first intervention. Furthermore, we investigate if we still can achieve identification when participation to the sequences is decided sequentially on the intermediate results. Identification can be obtained in each case for all parameters of interest.
Massive Mortality of a Planktivorous Seabird in Response to a Marine Heatwave

Climate change has exacerbated the occurrence of large‐scale sea surface temperature anomalies, or marine heatwaves (MHWs)—extreme phenomena often associated with mass mortality events of marine organisms. Using a combination of citizen science and federal data sets, we investigated the causal mechanisms of the 2014/2015 die‐off of Cassin's Auklets (Ptychoramphus aleuticus), a small zooplanktivorous seabird, during the NE Pacific MHW of 2013–2015. Carcass deposition followed an effective reduction in the energy content of mesozooplankton, coincident with the loss of cold‐water foraging habitat caused by the intrusion of the NE Pacific MHW into the nearshore environment. Models examining interannual variability in effort‐controlled carcass abundance (2001–2014) identified the biomass of lipid‐poor zooplankton as the dominant predictor of increased carcass abundance. In 2014, Cassin's Auklets dispersing from colonies in British Columbia likely congregated into a nearshore band of cooler upwelled water and ultimately died from starvation following the shift in zooplankton composition associated with onshore transport of the NE Pacific MHW. For Cassin's Auklets, already in decline due to ocean warming, large‐scale and persistent MHWs might represent a global population precipice.
Consumers and Their Brands: Developing Relationship Theory in Consumer Research

Although the relationship metaphor dominates contemporary marketing thought and practice, surprisingly little empirical work has been conducted on relational phenomena in the consumer products domain, particularly at the level of the brand. In this article, the author: (1) argues for the validity of the relationship proposition in the consumer-brand context, including a debate as to the legitimacy of the brand as an active relationship partner and empirical support for the phenomenological significance of consumer-brand bonds; (2) provides a framework for characterizing and better understanding the types of relationships consumers form with brands; and (3) inducts from the data the concept of brand relationship quality, a diagnostic tool for conceptualizing and evaluating relationship strength. Three in-depth case studies inform this agenda, their interpretation guided by an integrative review of the literature on person-to-person relationships. Insights offered through application of inducted concepts to two relevant research domains — brand loyalty and brand personality — are advanced in closing. The exercise is intended to urge fellow researchers to refine, test, and augment the working hypotheses suggested herein and to progress toward these goals with confidence in the validity of the relationship premise at the level of consumers’ lived experiences with their brands.
Development of fauna of water beetles (Coleoptera) in waters bodies of a river valley – habitat factors, landscape and geomorphology

The goal of the study was to identify the beetle fauna of a small lowland river valley against its spatial arrangement and the directions of beetle migrations between habitats, as well as to determine which environmental factors affect the characteristics of water beetle populations in a river valley's lentic water bodies. The field studies were carried out in various types of water bodies. 112 species of beetles with various ecological characteristics were identified. It was demonstrated that the diversity of water bodies in the valley is conducive to high local species richness. At the same time, the observed high degree of faunistic individualism may be regarded as a sign of poor symmetry in the directions of fauna propagation, particularly that of stagnobionts. The authors argue that high individualism is the consequence of poor hydrological contact between the water bodies due to topography and rare instances of high tide in the river, which, in turn, is the reason for active overflights remaining the main mean of migration between those water bodies. The factors restricting migration of fauna between the water bodies include certain landscape characteristics of the catchment which form topographical obstacles, mainly numerous and dense forest areas. The character of fauna in the respective types of water bodies is affected also by internal environmental factors, particularly the degree to which they are overgrown with macrophytes, type of bottom, type of mineral and organic matter as well as physical parameters of water, such as saturation, pH, temperature and biological oxygen demand.
Can Mimicking Infants’ Early Experience Facilitate Adult Learning? A Critique of Hudson Kam (2017)

ABSTRACT Why do adults seem to struggle more than children in learning a second language, despite being better at a range of other cognitive skills? The source of L1-L2 differences in language learning is one of the most debated topics in the study of language. One hypothesis is that L1-L2 differences are primarily experience-based, with language learning abilities themselves showing a high degree of plasticity. Hudson-Kam (2018) recently presented findings that seem to go against this hypothesis: in five studies, adults failed to show better learning in a more infant-like environment. In this article, I offer a theoretical and empirical critique of these findings and outline some open questions for investigating experience-based explanations for L1-L2 differences. In short, the main critique has to do with how we define what infant-like (or child-like) learning is and how we identify which aspects of children’s experience facilitate which aspects of language learning.
One-Shot Learning on Attributed Sequences

One-shot learning has become an important research topic in the last decade with many real-world applications. The goal of one-shot learning is to classify unlabeled instances when there is only one labeled example per class. Conventional problem setting of one-shot learning mainly focuses on the data that is already in a feature space (such as images). However, the data instances in real-world applications are often more complex and feature vectors may not be available. In this paper, we study the problem of one-shot learning on attributed sequences, where each instance is composed of a set of attributes (e.g., user profile) and a sequence of categorical items (e.g., clickstream). This problem is important for a variety of real-world applications ranging from fraud prevention to network intrusion detection. This problem is more challenging than the conventional one-shot learning since there are dependencies between attributes and sequences. We design a deep learning framework OLAS to tackle this problem. The proposed OLAS utilizes a twin network to generalize the features from pairwise attributed sequence examples. Empirical results on real-world datasets demonstrate the proposed OLAS can outperform the state-of-the-art methods under a rich variety of parameter settings.
Health Financing and Catastrophic Payments for Health Care: Evidence from Household‐level Survey Data in Botswana and Lesotho

: The financing of health care is a complex issue for policy makers. This is because high out-of-pocket payments on health care have been found to further impoverish the poor who have limited income to divide among basic necessities of which health care is one — catastrophic health expenditure (CHE). The Millennium Development Goals (MDGs) may be difficult to attain with high out-of-pocket payments by the poor; this is an issue of serious concern and highlights the need for the kind of analyses in this paper. The analysis used data collected by the Household and Expenditure Survey (HIES) 2002/2003 for Botswana and by the Household Budget Survey (HBS) 2002/2003 for Lesotho. Our results showed that in Botswana the proportion of households facing CHE at the 20 per cent and 40 per cent thresholds was 11 per cent and 7 per cent respectively, and the share of out-of-pocket health payments during the survey period was about 0.93 per cent. For Lesotho the proportions of those facing CHE expenditure at the 20 per cent and 40 per cent thresholds were 3.22 per cent and 1.25 per cent, and the share of out-of-pocket payment in total monthly expenditure was 1.34 per cent. Results from regression analyses suggest that having at least one senior member in the household imposes a higher risk for CHE for the household in Lesotho; for Botswana gender and education status of household head influence the probability of facing CHE. In designing health systems, policy makers need to ensure that households are not only able to access health services when needed, but that they are also protected from facing financial catastrophe by reducing out-of-pocket payments.
SMOOTH(ER) STELLAR MASS MAPS IN CANDELS: CONSTRAINTS ON THE LONGEVITY OF CLUMPS IN HIGH-REDSHIFT STAR-FORMING GALAXIES

We perform a detailed analysis of the resolved colors and stellar populations of a complete sample of 323 star-forming galaxies (SFGs) at 0.5 < z < 1.5 and 326 SFGs at 1.5 < z < 2.5 in the ERS and CANDELS-Deep region of GOODS-South. Galaxies were selected to be more massive than 1010 M☉ and have specific star formation rates (SFRs) above 1/tH. We model the seven-band optical ACS + near-IR WFC3 spectral energy distributions of individual bins of pixels, accounting simultaneously for the galaxy-integrated photometric constraints available over a longer wavelength range. We analyze variations in rest-frame color, stellar surface mass density, age, and extinction as a function of galactocentric radius and local surface brightness/density, and measure structural parameters on luminosity and stellar mass maps. We find evidence for redder colors, older stellar ages, and increased dust extinction in the nuclei of galaxies. Big star-forming clumps seen in star formation tracers are less prominent or even invisible in the inferred stellar mass distributions. Off-center clumps contribute up to ∼20% to the integrated SFR, but only 7% or less to the integrated mass of all massive SFGs at z ∼ 1 and z ∼ 2, with the fractional contributions being a decreasing function of wavelength used to select the clumps. The stellar mass profiles tend to have smaller sizes and M20 coefficients, and higher concentration and Gini coefficients than the light distribution. Our results are consistent with an inside-out disk growth scenario with brief (100–200 Myr) episodic local enhancements in star formation superposed on the underlying disk. Alternatively, the young ages of off-center clumps may signal inward clump migration, provided this happens efficiently on the order of an orbital timescale.
Carbonatites and associated nephelinites fromSao Vicente, Cape Verde Islands

The island of Sao Vicente has the most abundant carbonatite outcrops in the Cape Verde Islands. A field survey of the main outcrops has shown that they consist of extrusive carbonatites, carbonatite dykes and small apophyses of intrusive carbonatite. These outcrops are spatially related to nephelinites. The compositions of the extrusive carbonatites and dykes plot close to, and within, the magnesiocarbonatite field. In contrast, the intrusive carbonatites are calciocarbonatites, with similar average strontium contents to those of extrusive carbonatites and dykes (around 4000 ppm), but remarkably low barium, niobium and total rare earth element concentrations. Whole-rock geochemistry indicates a strong affinity between the nephelinites and intrusive carbonatites, such that the latter could represent fractionation products of the same parental magma. This is in agreement with radiogenic isotope geochemistry, which shows a very restricted range of compositions in the Sr, Nd and Pb systems. Fractionation from a common parental magma occurred in two main steps: high-temperature nephelinite crystallization and high-temperature carbonatite immiscibility. The carbonatitic melts crystallized in two different environments, as follows: (1) a shallow intrusive environment, giving rise to the early calciocarbonatite cumulates; and (2) a vapour-dominated, extrusive environment, producing the later magnesiocarbonatites.
Global talent management and inpatriate social capital building: a status inconsistency perspective

Distinct to expatriate managers at the subsidiary-level, inpatriate managers' influence at the headquarter (HQ)-level is controlled by the extent to which an inpatriate manager is able to ‘win’ status from HQ personnel. The primary goal of the paper is to conceptualize how organizational support, in the form of global talent management (GTM) practices, can alleviate inpatriates' difficulties in building social capital at HQ. Building social capital at HQ is vital for inpatriates to attain status in order to build the inter-unit social capital that enables them to pursue their boundary-spanning role across HQs and subsidiaries. Status inconsistency theory is put forward to recognize the personal, professional and structural incongruence of events and activities at HQ carried out with respect to inpatriates. We argue that inpatriate managers become empowered at HQ only when social capital is accumulated whereby social capital is driven by an acknowledgment of inpatriates as a legitimate staffing option. The relationship between GTM practices and social capital building needs to be managed properly by inpatriates themselves as well as by the organization. A future research agenda helping to build social capital of inpatriates through GTM infrastructure is discussed and propositions are offered throughout.
Determining the relative stability of leading-edge vortices on nominally two-dimensional flapping profiles

Abstract It is hypothesized that the relative stability of leading-edge vortices (LEVs) on flapping profiles can be improved by moderating LEV growth through spanwise vorticity convection and vortex stretching. Moreover, it is hypothesized that the reduced frequency $k$ and profile sweep ${\it\Lambda}$ are critical in predicting relative LEV stability as determined by the aforementioned effects. These hypotheses are then confirmed experimentally with phase-averaged particle image velocimetry (PIV) and three-dimensional particle tracking velocimetry. In particular, more stable LEVs are observed at higher reduced frequencies, which is argued to represent the ratio between the limiting vortex size and the rate of vorticity feeding. The introduction of profile sweep increased both relative LEV stability and spanwise vorticity transport. It is thought that spanwise vorticity transport improved LEV stability by acting as a sink for vorticity generated in the leading-edge shear layer.
Promoting online students’ engagement and learning in science and sustainability preservice teacher education

At James Cook University, a core first-year subject within the Bachelor of Education, Foundations of Sustainability in Education (FSE), sees students investigate the underlying science and complexity of socioecological challenges through inquiry, place-based learning, experimentation and consideration of classroom practice. Given that this subject is delivered across modes, a blended learning approach that encompasses an innovative use of learning technologies and careful consideration of pedagogy provides opportunity for both on-campus and online students to engage in active, learner-centred, collaborative, experiential and praxis-oriented learning experiences (Wals & Jickling, 2002). In this paper, we draw upon Pittaway's (2012) engagement framework and Herrington, Herrington, Oliver, Stoney and Willis's (2001) guidelines for quality online courses to explore students' perceptions and experiences of FSE. We investigate how a blended learning design can support the development of a robust foundational knowledge base in science and sustainability education, and engagement in active, experiential and praxis-oriented learning experiences for first year online students. This paper furthers the discussion around best pedagogical practice and blended learning design for science and sustainability education in online preservice teacher education, and in other disciplines in teacher education that call for hands-on learning experiences in an online environment.