Miracle-dz/UniFAR-FTUs huggingface dataset:
A STUDY TO ASSESS TEACHER EDUCATORS' ATTITUDES TOWARDS TECHNOLOGY INTEGRATION IN CLASSROOMS

The aim of this study was to assess the teacher educators' attitudes towards technology integration in classrooms. 21 teacher educators from a teacher education college of north India participated in this study. The data were collected with the help of a Teacher Educators' Attitude towards ICT Scale containing forty items. The results show that most of the teacher educators have positive attitudes towards the general role that information and communication technology can play in education and in the educational process. The findings also reveal that no gender differences exist on attitudestowardsICTinteachertraining. Furtheranalysisshedlightondifferencesin attitudes with respect to age.
A clinical predictive model of renal injury in children with isolated antenatal hydronephrosis

Abstract Background Antenatal hydronephrosis (ANH) affects ∼1–5% of pregnancies. The aim of this study was to develop a clinical prediction model of renal injury in a large cohort of infants with isolated ANH. Methods This is a longitudinal cohort study of 447 infants with ANH admitted since birth between 1989 and 2015 at a tertiary care center. The primary endpoint was time until the occurrence of a composite event of renal injury, which includes proteinuria, hypertension and chronic kidney disease (CKD). A predictive model was developed using a Cox proportional hazards model and evaluated by C-statistics. Results Renal pelvic dilatation (RPD) was classified into two groups [Grades 1–2 (n = 255) versus Grades 3–4 (n = 192)]. The median follow-up time was 6.4 years (interquartile range 2.8–12.5). Thirteen patients (2.9%) developed proteinuria, 6 (1.3%) hypertension and 14 (3.1%) CKD Stage 2. All events occurred in patients with RPD Grades 3–4. After adjustment, three covariables remained as predictors of the composite event: creatinine {hazard ratio [HR] 1.27, [95% confidence interval (CI) 1.05–1.56]}, renal parenchyma thickness at birth [HR 0.78(95% CI 0.625–0.991)] and recurrent urinary tract infections [HR 4.52 (95% CI 1.49–13.6)]. The probability of renal injury at 15 years of age was estimated as 0, 15 and 24% for patients assigned to the low-risk, medium-risk and high-risk groups, respectively (P < 0.001). Conclusion Our findings indicate an uneventful clinical course for patients with Society for Fetal Urology (SFU) Grades 1–2 ANH. Conversely, for infants with SFU Grades 3–4 ANH, our prediction model enabled the identification of a subgroup of patients with increased risk of renal injury over time.
Nursing students serve and learn how to check, change, and control blood pressure in the local community

Background: High blood pressure is currently affecting 103 million people in the United States and is a major risk factor for cardiovascular disease, stroke, and heart failure. The American Heart Association (AHA) launched Check. Change. Control. Program (CCC program). The program is an evidence-based hypertension management program that utilizes blood pressure self-monitoring to empower patients/participants to take ownership of their cardiovascular health.Project: Following the Partnership Model for Service Learning, Miami University and The AHA propose implementing the “Serve and Learn How to Check, Change, and Control: A Community-Based Intervention to Improve Blood Pressure Control” to improve the BP of a diverse group of residents in Middletown and Hamilton cities in Ohio.Participants: Fifteen nursing students served as volunteer health mentors. Each nursing student recruited five community members over the age of 18 and checked their blood pressure two times every month for four months. 80 community membered were recruited and joined the project for four months.Results: At the end of the program, more than half of the participants (n = 41) had blood pressure improvement (decrease in systolic or/a diastolic). On third of Tier 1/ HYPERTENSION participants (n = 10) have moved from uncontrolled (> or = to 130/80) to controlled (< or = to 129/79) based on comparing the participants’ 1st blood pressure reading to their last.Conclusions: The extremely positive effects of this project are an eye-opening on the need of applying the program on a larger scale. To apply this program on a larger scale, partnerships with community organizations such as community health and wellness centers are needed. These partnerships will provide quality access to healthcare. The students will be able to meet participants where they are in their communities in a safe, vibrant, open and welcoming centers.
Developmental dynamics in chemical composition during fruit ripening of pomegranate

Pomegranate arils juice showed a significant (p<0.05) increase in sugars and soluble solids content during fruit development. However, titratable acidity and total phenolics of aril juice decreased with advancement of fruit maturity. There was 11.32 times increase in Vitamin C content of juice during fruit development, whereas about 2.38 fold decrease in juice acidity was recorded. The reducing sugars content in aril juice was about 76.35 % 81.93 % of total sugars. There was overall depletion of total phenolics content during course of fruit development. The results revealed that soluble solids content, SSC/TA ratio, juice pH, reducing sugars, non-reducing sugars, total sugars and Vitamin C of juice was abundant between 140-150 days after full bloom (DAFB). Whereas, TA and TP declined and reached minimum between 140150 DAFB. SSC/TA ratio showed positive correlation with pH, sugars and Vitamin C, but negatively correlated with TA and TP. The principal components analysis showed that full ripened fruit at 140-150 DAFB recorded higher positive score along component 1 and indicate optimum time of fruit harvest.
AUDIT FEES AND PRICING STRATEGY: DO RESTATEMENTS OF INTERNAL CONTROL REPORTS AND EARNINGS MATTER?

How to cite this paper: Lemonakis, C. , Ballas, P., Balla, V. , & Garefalakis, A. (2018). Audit fees and pricing strategy: Do restatements of internal control reports and earnings matter? Risk Governance and Control: Financial Markets & Institutions, 8(2), 63-73. http://doi.org/10.22495/rgcv8i2p4 Copyright © 2018 The Authors This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC
Differences in negative predictive value of prostate MRI based in men with suspected or known cancer

Objective To compare the negative predictive value (NPV) of multiparametric MRI for Gleason score (GS) ≥ 3+4 cancer and evaluate predictors of these tumors in men with suspected disease and under active surveillance (AS). Materials and Methods This retrospective study included 38 men with suspected prostate cancer and 38 under AS with scans assigned PI-RADS v2 scores 1 or 2 between May 2016 and September 2017. Biopsy results were no cancer, GS = 3+3, or GS ≥ 3+4. Pre-MRI PSA, gland volume, and PSA density were recorded. Chi-square, equality of proportions, and logistic regressions were used to analyze the data. Results Intermediate to high-grade cancer was found in 12.8% (95% CI = 2.3-23.3) and 35.9% (95% CI = 20.8-50.9) of men with suspected cancer, and under AS (p = 0.02), respectively. The NPV for GS ≥ 3+4 were 87.2% (suspected cancer; 76.7-97.7) and 64.1% (AS; 49.0-79.2). In neither group PSA significantly predicted cancer grade (p = 0.75 and 0.63). Although it did not reach conventional statistical significance, PSA density was a good predictor of cancer grade in men with suspected disease (p = 0.06), but not under AS (p = 0.62). Conclusion The NPV of multiparametric MRI for GS ≥ 3+4 is higher in men with suspected prostate cancer than in men under AS. PSA density ≤ 0.15 improved the prediction of intermediate to high-grade disease in patients without known cancer.
PHYTOCHEMISTRY, ANTIOXIDATIVE AND ANTIDIABETIC EFFECTS OF VARIOUS PARTS OF EUGENIA CARYOPHYLLATA THUNB. IN VITRO

Eugenia caryophyllata Thunb. possesses a wide variety of therapeutic potential and has been recog- nized as a source of antioxidative and antidiabetic agents. This study was designed to investigate and compare the antioxidative and antidiabetic effects of different parts (bud, leaf, stem and root) of E. caryophyllata. Samples were sequentially extracted using solvents of increasing polarity and investigated for 1,1-diphenyl-2- picrylhydrazyl (DPPH) radical scavenging activity, total reducing power, inhibition of hemoglobin glycosyla- tion, α-amylase and α-glucosidase activities as markers of in vitro antidiabetic effects. Phytochemicals were analyzed using gas chromatography-mass spectrometry (GC-MS) analysis. The ethanol (EtOH) extracts of the bud, leaf and stem exhibited a higher total polyphenol and flavonoid content compared to other extracts, with the EtOH extracts of the bud and leaf exhibiting lower IC50 values than the extracts of the other plant parts for all the models used in this study (DPPH bud: 0.17 ± 0.20 mg/mL; leaf: 0.03 ± 0.01 mg/mL; hemoglobin gly- cosylation: bud: 0.17 ± 0.02 mg/mL; 0.83 ± 0.04 mg/mL; α-amylase: bud: 0.20 ± 0.02 mg/mL; 322.27 ± 73.29 mg/mL; α-glucosidase: bud: 0.03 ± 0.01 mg/mL; 0.74 ± 0.02 mg/mL). A similar result was observed for the reducing potentials of Fe 3+ to Fe 2+ by the extract. The GC-MS analysis of these parts indicated several aromat- ic phenols, acids, carophyllene and long chain aliphatic acids.Conclusively, various solvent extracts from the leaf, bud and stem of E. caryophyllata showed higher antioxidative and antidiabetic effects in comparison to common standards used in these assays.
Palbociclib in Patients With Pancreatic and Biliary Cancer With CDKN2A Alterations: Results From the Targeted Agent and Profiling Utilization Registry Study.

PURPOSE The Targeted Agent and Profiling Utilization Registry (TAPUR) Study identifies signals of antitumor activity of commercially available targeted agents in patients with advanced cancers that harbor genomic alterations known as drug targets. In this article, data from two cohorts of patients with pancreatic and biliary cancers with CDKN2A loss or mutation treated with palbociclib are reported. METHODS Eligible patients age 12 years and older with advanced measurable or evaluable solid tumors are provided treatment according to protocol-specified genomic matching rules. The primary study end point is objective response or stable disease of at least 16 weeks duration. For each cohort, a Simon two-stage design was used with a futility evaluation after 10 patients. Secondary end points include safety, progression-free survival (PFS), and overall survival (OS). RESULTS Between July 2016 and November 2017, 12 and 10 patients with pancreatic and biliary cancer, respectively, with CDKN2A loss or mutation were treated with palbociclib. Twenty evaluable patients (10 per cohort) were included in the analysis. No patients had objective response or stable disease at 16 weeks, and both cohorts were closed. Two patients, neither with response, were determined to be ineligible. All patients were evaluated for safety, PFS, and OS. A median PFS of 7.2 weeks (90% CI, 4.0 to 8.0 weeks) and median OS of 12.4 weeks (90% CI, 4.7 to 23.1 weeks) were observed in the pancreatic cohort. A median PFS of 7.3 weeks (90% CI, 3.9 to 7.9 weeks) and median OS of 11.1 weeks (90% CI, 5.1 to 14.0 weeks) were observed in the biliary cohort. No unexpected toxicities were observed. CONCLUSION Palbociclib monotherapy does not have clinical activity in patients with advanced pancreatic or biliary cancers with CDKN2A loss or mutation. Toxicity is similar to reported experience with palbociclib in other tumor types.
Semiorthogonal decompositions and birational geometry of del Pezzo surfaces over arbitrary fields

We study the birational properties of geometrically rational surfaces from a derived categorical perspective. In particular, we give a criterion for the rationality of a del Pezzo surface S over an arbitrary field, namely, that its derived category decomposes into zero‐dimensional components. When S has degree at least 5 we construct explicit semiorthogonal decompositions by subcategories of modules over semisimple algebras arising as endomorphism algebras of vector bundles and we show how to retrieve information about the index of S from Brauer classes and Chern classes associated to these vector bundles.
Recovery after surgery: do not forget to check iron status before

Abstract The perioperative period poses a risk for anemia due to the high prevalence of pre-existing anemia secondary to underlying pathologies in patients who are candidates for surgery, and as a result of the increased blood loss caused by surgery. Pre-operative anemia is an independent risk factor associated with higher risk of blood transfusion and negative surgery outcomes. Anemia and iron deficiency (ID), the main causes of pre-operative anemia, can be easily diagnosed with blood testing and are readily treated before elective surgery. However, pre-surgical screening and treatment of anemia and ID are frequently overlooked. These topics were presented and discussed at the symposium entitled “Recovery after Surgery: Don’t Forget to Check Iron Status Before”, held at the 11th Annual Meeting of the European Urogynaecological Association (EUGA) in October 2018 in Milan. The objectives of the symposium were to stress the high prevalence and the consequences of pre-operative anemia, illustrated with three clinical cases of women undergoing surgery, and to choose the best option for iron supplementation. In conclusion, it is essential to take time to diagnose and treat iron deficiency anemia (IDA) before surgery. The first-line treatment is oral iron when surgery can be delayed and when there is no intolerance to oral treatment or inefficient uptake, as in the case of iron sequestration or absorption disorders. Among iron preparations, ferrous sulfate in a polymeric complex (FSPC) was found to be one of the treatments of choice to improve hemoglobin iron stores and quality of life in IDA patients.
Committee Hearings of the Scottish Parliament: Evidence Giving and Policy Learning

The Scottish Parliament's committees were designed to provide both an alternative policy agenda to government and a venue for debate and policy learning among a broad cross-section of organised interests and citizens. Work to date suggests the former has not materialised, but what about the latter? This article reports fresh data on the contribution of committee ‘hearings’ to (i) broadening the scope of ‘interests’ heard by Parliament, and (ii) facilitating policy learning among organised interests. Despite the Parliament's founding vision advocating a move away from ‘the usual suspects’, the evidence shows that hearings across issues and committees feature a recurrent core of organisations which exemplify the ‘usual suspects’ label, alongside a large number of ‘policy niche’ specialists. In relation to policy learning, the evidence shows that respondents view committee hearings favourably, with low levels of process dissatisfaction and a considerable minority of respondents shifting views as a result of participation.
Effect of Nitrogen and Phosphorus Level on Dry Matter Yield at Different Growth Stages of Popcorn in South Saurashtra Region of Gujarat, India

In Indian agriculture, maize assumes a special significance on account of its utilization as food, feed and fodder besides several industrial uses. According to latest data (2012-13), it is being cultivated on 8.49 million hectares with 80% area during kharifseason. Nowadays, the maize corn used for popcorn, is profitable for a lot of producers and traders. Maize production is 21.28 million tonnes, with an average productivity of 2.5 t ha -1 (NIIR, 2013). The current maize is grown on 9.3 million hectares with production of 24.2 million tonnes and productivity of 2602 kg ha -1 in the country (FAO STAT, 2014). Despite maize being predominantly rainfed crop its productivity is more than rice which is mainly grown under assured irrigated/rainfed conditions. Maize contributes nearly 9% in the national food basket and more than 400 billion to the agricultural GDP at current prices. In Gujarat, the important districts growing maize are Dahod, Panchmahal, Vadodara, Sabarkantha, Kheda, Banaskantha, Bharuch, Anand and Dang.
Spectral shaping of laser generated proton beams

The rapid progress in the field of laser particle acceleration has stimulated a debate about the promising perspectives of laser based ion beam sources. For a long time, the beams produced exhibited quasi-thermal spectra. Recent proof-of-principle experiments demonstrated that ion beams with narrow energy distribution can be generated from special target geometries. However, the achieved spectra were strongly limited in terms of monochromacity and reproducibility. We show that microstructured targets can be used to reliably produce protons with monoenergetic spectra above 2 MeV with less than 10% energy spread. Detailed investigations of the effects of laser ablation on the target resulted in a significant improvement of the reproducibility. Based on statistical analysis, we derive a scaling law between proton peak position and laser energy, underlining the suitability of this method for future applications. Both the quality of the spectra and the scaling law are well reproduced by numerical simulations.
Efficacy of a new oncolytic adenovirus armed with IL-13 against oral carcinoma models

Purpose The efficacy of traditional therapies for oral carcinoma (OC) is limited. Oncolytic adenovirus, a novel strategy of cancer therapy, shows potential use in OC treatment. However, its clinical application is limited by pre-existing neutralizing antibodies. Thus, this study aimed to examine the efficacy of a new modified adenovirus against OC in vitro and in vivo. Materials and methods A multiple modified adenovirus (MMAD) armed with IL-13 (MMAD-IL-13) was constructed, and its effect on Cal-27 cells was examined. The potency of MMAD-IL-13 was examined in vitro and in vivo. For in vitro experiment, CCK-8 kit was used to determine the IC50 of MMAD-IL-3 in OC cell lines. For in vivo experiment, Cal-27 xenograft models were used to determine the antitumor effect of MMAD-IL-13. Apoptosis was measured in Cal-27 cells by Western blotting assay. Immunity response was detected in Cal-27 xenograft models 7 days after intratumoral injection with MMAD-IL-13. The potency of MMAD and MMAD-IL-13 was compared in Cal-27 peripheral blood mononuclear cells (PBMCs) models. Results MMAD-IL-13 was successfully constructed; the harvested virus could be replicated and they overexpressed human IL-13 in Cal-27 cells. Compared with MMAD, MMAD-IL-13 showed enhanced antitumor effect in vitro by inducing apoptosis and reducing percentage of M2 macrophages in tumor environment in vivo. MMAD-IL-13 also showed potent antitumor effect in Cal-27, SCC-4, and Tca8113 cells in vitro and in Cal-27 xenograft models in vivo. However, MMAD-IL13 did not harm normal human oral epithelial cells in vitro and exhibited no effect on body weight in Cal-27 xenograft models. In Cal-27 PBMC models, MMAD-IL-13 showed stronger antitumor effect than MMAD. Conclusion A new oncolytic adenovirus carrying the human IL-13 gene was constructed. This virus effectively led to remission of tumor development and death of OC cells in vivo and in vitro, showing its potential as a clinical cancer therapy.
Laminar and unstable burning velocities andMarkstein lengths of hydrogen – air mixtures at engine-like conditions

Hydrogen offers an attractive alternative to conventional fuels for use in spark ignition engines. It can be burned over a very wide range of equivalence ratios and with considerable exhaust gas recirculation. These help to minimise pumping losses through throttleless operation and oxides of nitrogen (NOx) production through reduced temperature. Full understanding of hydrogen-fuelled engine operation requires data on the laminar burning rate of hydrogen–air residuals under a wide range of conditions. However, such data are sparse. The present work addresses this need for experimental data. Spherically expanding H2–air flames were measured at a range of temperatures, pressures, and equivalence ratios and with varying concentrations of residuals of combustion. Unstretched burning velocities, ul, and Markstein lengths, Lb, were determined from stable flames. At the higher pressures, hydrodynamic and diffusional-thermal instabilities caused the flames to be cellular from inception and prohibited the derivation of values of ul and Lb. The effect of pressure on the burning rate was demonstrated to have opposing trends when comparing stoichiometric and lean mixtures. The present measurements were compared with those available in the literature, and discrepancies were attributed to neglect, in some works, the effects of stretch and instabilities. From the present measurements, the effects of pressure, temperature, and residual gas concentration on burning velocity are quantified for use in a first step towards a general correlation. 2004 by the Combustion Institute. Published by Elsevier Inc. All rights reserved.
USE OF IRRADIATION TO CONTROL MICROORGANISMS AND EXTEND THE REFRIGERATED MARKET LIFE OF CHICKEN SAUSAGE

This study investigated the microbial, chemical and sensorial properties of chicken sausage exposed to gamma irradiation and stored at 0-4 o C. Chicken sausage was treated with 0, 2, 4 or 6 kGy doses of gamma irradiation. Microbial, chemical, and sensory analyses of chicken sausage were evaluated at 0, 4, 8, 12, 16 and 20 weeks of storage. Irradiation at 2, 4 and 6 kGy significantly reduced the counts of total viable (mesophilic aerobic) plate counts (TPCs), fecal coliform and yeast load and prolonged the refrigerated shelf-life of chicken sausage. Irradiation significantly decreased their amount of total acidity, volatile basic nitrogen (VBN), and thiobarbituric acid reactive substances (TBARS), while storage increased the total acidity, VBN and TBARS for irradiated and non-irradiated samples. The percentage of protein slightly increased in irradiated samples with higher doses, while the percentage of fat significantly decreased. Gamma irradiation showed no significant effect on the sensory properties of chicken sausage.
A Review of Morphological Analysis Strategies on Vocabulary Outcomes with ELLs.

In this article, the literature on instruction in morphological analysis strategies with English Language Learners (ELLs) is reviewed to identify vocabulary outcomes for these students. The nature of instruction and quality of outcomes are examined for ELLs in general, and also for those with or at risk of reading disabilities. A total of nine studies met inclusion criteria for this review. While preliminary, results suggest that morphological analysis strategies are a promising approach to improving the vocabulary knowledge of ELLs, including those with or at risk of reading disabilities. Future research in this area is worth exploring, and several directions are provided.
Preparation and Dating of Mortar Samples—Mortar Dating Inter-Comparison Study (MODIS)

Abstract Seven radiocarbon laboratories: Åbo/Aarhus, CIRCE, CIRCe, ETHZ, Poznań, RICH, and Milano-Bicocca performed separation of carbonaceous fractions suitable for 14C dating of four mortar samples selected for the MOrtar Dating Inter-comparison Study (MODIS). In addition, optically stimulated luminescence (OSL) analyses were completed by Milano-Bicocca and IRAMAT-CRP2A Bordeaux. Each laboratory performed separation according to laboratory protocol. Results of this first intercomparison show that even though consistent 14C ages were obtained by different laboratories, two mortars yielded ages different than expected from the archaeological context.