Miracle-dz/UniFAR-FTUs huggingface dataset:
Myoelectric Pattern Recognition Based on Muscle Synergies for Simultaneous Control of Dexterous Finger Movements

Motor activities during daily life always involve simultaneous control of multiple degrees of freedom (DOFs), which has not yet been fully explored in myoelectric control due to difficulty in sufficiently decoding the complex neural control information. This study presents a novel framework for simultaneous myoelectric control based on pattern recognition incorporated with a muscle synergy motor control strategy for each DOF. An experiment for discriminating 18 dexterous finger movement tasks was designed to evaluate the performance of the framework for the simultaneous control of 5 DOFs. Task discrimination was assessed with 18 neurologically intact subjects, and the framework exhibited high accuracy (96.79% ±2.46%), outperforming three other methods, including the routine myoelectric pattern-recognition approach for conventional sequential control (p<0.001). Furthermore, the feasibility of the proposed framework is also demonstrated with data from paretic muscles of two stroke subjects. This study offers a feasible solution for simultaneous myoelectric control of multiple DOFs, which has great potential for natural implementation in prosthetic hand devices and robotic training systems, especially for dexterous finger movements.
The Use of Oral Sucrose to Relieve Minor Procedural Pain in Neonates

Objective: To evaluate the effectiveness of oral sucrose as analgesic for minor painful procedures in neonates. Methods: A case control study was conducted in the neonatal intensive care unit at King Hussein Medical Center during the period between June 1 and December 30, 2009. A total of 100 preterm and term neonates with postnatal ages ranging from one to 20 days, who underwent heel pricks for collection of blood for bilirubin estimation were randomly assigned into two groups. The treatment group received 24% sucrose solution two minutes before heel prick and the control group did not receive sucrose solution. The pain was assessed using the Premature Infant Pain Profile which is a multidimensional acute pain rating scale with scores ranging from 0 (no pain) to 21 (maximum pain). The exclusion criteria included the following: age less than 30 weeks gestational age, newborns on ventilators, newborns with major congenital or neurologic anomalies or clinical diagnosis of birth asphyxia or seizures, those on analgesics or sedatives and sick newborns with unstable vital signs. The student's t test was used to compare the relevant data. P value less than 0.05 was considered to indicate statistical significance. Results: A total of 100 newborns, who were born with 30 weeks and above gestational age, were included in the study and divided into treatment and control groups in equal numbers. The mean Premature Infant Pain Profile scores were significantly lower in the treatment group, than in the control. Conclusion: Our study suggests that sucrose is an effective non-pharmacological analgesic for minor painful procedures in neonates.
Rising trends of obesity and abdominal obesity in 10 years of follow-up among Tehranian adults: Tehran Lipid and Glucose Study (TLGS)

Abstract Objective Some recent studies have shown stablity or declining trends in obesity while others still report increasing trends. The present study aimed to investigate the trends of obesity and abdominal obesity in Tehranian adults during a median follow-up of 10 years. Design Prospective cohort study. Setting Community-based data collection from the Tehran Lipid and Glucose Study (TLGS). Subjects Participants from four phases of the TLGS from 1999 to 2011 (n 10 368), aged ≥20 years. Results The crude prevalence of obesity and abdominal obesity increased from 23·1 % and 47·9 % at baseline to 34·1 % and 71·1 % at the end of follow-up, respectively. Generalized estimating equation (GEE) models were used to analyse the correlated data and calculate the relative risks (RR). Risks of obesity and abdominal obesity increased over the whole study period for men (RR=1·62; 95 % CI 1·49, 1·76 and RR=1·46; 95 % CI 1·41, 1·52, respectively) and women (RR=1·24; 95 % CI 1·19, 1·29 and RR=1·22; 95 % CI 1·18, 1·27, respectively). These rising trends were observed in all subgroups regardless of age, marital status and educational level. Conclusions Trends of obesity and abdominal obesity are increasing in Tehranian adults during a decade of follow-up in both genders and in all study subgroups. These results underscore the still growing obesity epidemic in the capital of Iran, calling for urgent action to educate people in lifestyle modifications and the need for effective preventive and educational strategies on obesity.
Lay Americans’ views of why scientists disagree with each other

A survey experiment assessed response to five explanations of scientific disputes: problem complexity, self-interest, values, competence, and process choices (e.g. theories and methods). A US lay sample (n = 453) did not distinguish interests from values, nor competence from process, as explanations of disputes. Process/competence was rated most likely and interests/values least; all, on average, were deemed likely to explain scientific disputes. Latent class analysis revealed distinct subgroups varying in their explanation preferences, with a more complex latent class structure for participants who had heard of scientific disputes in the past. Scientific positivism and judgments of science’s credibility were the strongest predictors of latent class membership, controlling for scientific reasoning, political ideology, confidence in choice, scenario, education, gender, age, and ethnicity. The lack of distinction observed overall between different explanations, as well as within classes, raises challenges for further research on explanations of scientific disputes people find credible and why.
Valuing Commercial Finance Companies

Valuing Commercial Finance Companies by David E. Coit, Jr. MBA, Keller Graduate School of Management, 1988 BS, Northern Illinois University, 1982 Doctoral Study Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Business Administration Walden University March 2016 Abstract Stakeholders are increasingly insistent that companies increase firm value. The problem is that stakeholders of financial services firms are unable to accurately determine firm value. The purpose of this correlational study was to examine the accuracy of 4 valuation models in predicting the market value of equity of commercial finance companies. Study participating companies were 8 listed U.S. or Canadian commercial finance companies.Stakeholders are increasingly insistent that companies increase firm value. The problem is that stakeholders of financial services firms are unable to accurately determine firm value. The purpose of this correlational study was to examine the accuracy of 4 valuation models in predicting the market value of equity of commercial finance companies. Study participating companies were 8 listed U.S. or Canadian commercial finance companies. The theoretical constructs of the study included the accuracy of valuation models, modern portfolio theory, and the correlation of book value of equity to market value of equity. Financial information on participating companies obtained from public filings were input data in 4 valuation models. Multiple regression analysis of valuation model results and book value of equity (the predictor variables) were used to determine the accuracy of the models in predicting the market value of equity (response variable). The findings of the study showed that all 4 valuation models in combination with the book value of equity were statistically significant predictors of the market value of equity of the participating companies at the p < . 05 level. However, the dividend discount model (DDM) and residual income model (RIM) were statistically more accurate without the combination of book value of equity (p = .000 and p = .000, respectively) than the discounted cash flow and risk-adjusted discounted cash flow valuation models (p = .371 and p = .904, respectively). The results of this study contribute to positive social change by providing business leaders an ability to measure the effectiveness of their actions in creating firm value. Corporate social responsibility activities correlate to value creation for firms that engage in promoting employee welfare and other stakeholder welfare. Valuing Commercial Finance Companies by
RFID data filtering algorithm in supply chain

Radio-frequency identification technology has been regarded as an essential role in supply chain management especially for its data collection capability for retailers to make decisions. However, lots of false readings could result in totally opposite resolutions. In this paper, we present seven models and their corresponding algorithms to filter these raw data so that managers can make good use of collected RFID data in supply chain management.
A Partisan Model of Electoral Reform

We propose a model of public response to politicized election reform. In this model, rival partisan elites send signals on the need and consequences of a proposed reform, with partisans in public adopting those positions. We apply this to test how state use of voter identification laws corresponded with public evaluations of the conduct of a state’s elections. We find that the relationship between photo identification laws and confidence in state elections was polarized and conditioned by party identification in 2014. Democrats in states with strict photo identification laws were less confident in their state’s elections. Republicans in states with strict identification laws were more confident than others. Results suggest strict photo identification laws are failing to instill broad-based confidence in elections, and that the reform could correspond with diminished confidence among some.
Formulation and characterisation of magnetic resonance imageable thermally sensitive liposomes for use with magnetic resonance-guided high intensity focused ultrasound

Purpose: Objectives of this study were to: 1) develop iLTSL, a low temperature sensitive liposome co-loaded with an MRI contrast agent (ProHance® Gd-HP-DO3A) and doxorubicin, 2) characterise doxorubicin and Gd-HP-DO3A release from iLTSL and 3) investigate the ability of magnetic resonance-guided high intensity focused ultrasound (MR-HIFU) to induce and monitor iLTSL content release in phantoms and in vivo. Methods: iLTSL was passively loaded with Gd-HP-DO3A and actively loaded with doxorubicin. Doxorubicin and Gd-HP-DO3A release was quantified by fluorescence and spectroscopic techniques, respectively. Release with MR-HIFU was examined in tissue-mimicking phantoms containing iLTSL and in a VX2 rabbit tumour model. Results: iLTSL demonstrated consistent size and doxorubicin release kinetics after storage at 4°C for 7 days. Release of doxorubicin and Gd-HP-DO3A from iLTSL was minimal at 37°C but fast when heated to 41.3°C. The magnitude of release was not significantly different between doxorubicin and Gd-HP-DO3A over 10 min in HEPES buffer and plasma at 37°, 40° and 41.3°C (p > 0.05). Relaxivity of iLTSL increased significantly (p < 0.0001) from 1.95 ± 0.05 to 4.01 ± 0.1 mMs−1 when heated above the transition temperature. Signal increase corresponded spatially and temporally to MR-HIFU-heated locations in phantoms. Signal increase was also observed in vivo after iLTSL injection and after each 10-min heating (41°C), with greatest increase in the heated tumour region. Conclusion: An MR imageable liposome formulation co-loaded with doxorubicin and an MR contrast agent was developed. Stability, imageability, and MR-HIFU monitoring and control of content release suggest that MR-HIFU combined with iLTSL may enable real-time monitoring and spatial control of content release.
A genotype–phenotype association approach to reveal thermal adaptation in Daphnia galeata

Altering thermal environments impose strong selection pressures on organisms, whose local persistence depends on adaptive phenotypic plastic and genetic responses. Thus far, adaptive change is monitored using phenotypic shifts or molecular markers, although inevitable obstacles are inherent in both methods. In order to circumvent these, it is necessary to find a causal link between adaptive alleles and fitness. Combining both approaches by linking genetic analyses and life-history measurements, a potential genotype-phenotype relationship can be assessed and adaptation at the molecular level demonstrated. For our study, clonal lineages of the freshwater keystone species D. galeata from seven different populations distributed along a latitudinal gradient across Europe were tested for local thermal adaptation in common garden experiments. Fitness-related life-history responses were quantified under different thermal regimes and experimental clones were genotyped at three candidate gene marker loci to investigate a potential genotype-phenotype association. The analyses of the life-history data showed a significant temperature effect on several fitness-related life-history traits recorded in our experiments. However, we could not detect evidence for a direct association at neither candidate gene locus between genotypes and life-history traits. The observed phenotypic shifts might therefore not be based on the tested marker loci EA, M and TF, or in general not coding sequence-based and thus rather reveal phenotypic plasticity in response to thermal variation. Nonetheless, we revealed significant genotype by environment (GxE) interactions at all tested loci, potentially reflecting a contribution of marker loci to certain life-history trait values and contribution of multiple genetic loci to phenotypic traits.
Effect of Lanthanum Carbonate Treatment on Bone in Japanese Dialysis Patients With Hyperphosphatemia

Lanthanum carbonate (LC), a newly developed non‐calcium‐containing phosphate binder, has been shown to possess high phosphate‐binding capacity and safety when used for hyperphosphatemia in patients with chronic kidney disease undergoing dialysis. The effects of LC on bone metabolism in Japanese dialysis patients have not been investigated; therefore, we performed histomorphometric analysis on bone from dialysis patients with hyperphosphatemia. This was a prospective, open‐label study in Japanese chronic kidney disease patients on dialysis, with a flexible daily dosage of 750–4500 mg to achieve target phosphorus levels of 3.5–5.5 mg/dL (1.10–1.78 mmol/L). Bone biopsy samples for histomorphometric analysis were obtained at baseline and after treatment with LC. The median bone lanthanum level increased during the LC treatment from 54.1 µg/kg at baseline to 4270.9 µg/kg at three years. After one year of treatment with LC, two cases with an initial classification of osteitis fibrosa improved toward normal bone turnover. The diagnosis of normal remained the same for up to three years. We also noted that two cases with a baseline classification of adynamic bone disease improved after one year, and was maintained for three years. Our data suggest that LC is effective not only for treating hyperphosphatemia, but also for improving renal osteodystrophy in Japanese dialysis patients.
Three-dimensional simulations of random dopant and metal-gate workfunction variability in an In0.53Ga0.47As GAA MOSFET

We investigate the impacts of random dopant (RD) and gate workfunction variability on the subthreshold characteristics of a 50-nm-gate-length inversion-mode gate-all-around In0.53Ga0. 47As MOSFET using a 3-D finite-element quantum-corrected drift-diffusion device simulator calibrated to experimental data. We have studied threshold voltage, off-current, and subthreshold slope variations. The workfunction variations on the subthreshold characteristics dominate and decrease with the reduction in grain diameter. The simulated grain diameters of 10, 7, and 5 nm exhibit threshold voltage standard deviations of 52, 41, and 27 mV, respectively. These values are larger than those observed in TiN-metal-gate Si FinFETs for a similar gate length. The impact of RD fluctuations is negligible when compared with bulk Si MOSFETs, giving a threshold voltage spread of only 6 mV.
3-[3-(3-florophenyl-2-propyn-1-ylthio)-1, 2, 5-thiadiazol-4-yl]-1, 2, 5, 6-tetrahydro-1- methylpyridine oxalate, a novel xanomeline derivative, improves neural cells proliferation and survival in adult mice

The present study analyzed the influence of 3-[3-(3-florophenyl-2-propyn-1-ylthio)-1, 2, 5-thiadiazol-4-yl]-1, 2, 5, 6-tetrahydro-1-methylpyridine oxalate (EUK1001), a novel xanomeline derivative of the M1/M4 receptor agonist, on hippocampal neurogenesis in adult C57BL6 mice. Results showed that 15-day EUK1001 treatment via intraperitoneal injection promoted neural cell proliferation in the dentate gyrus, although cell differentiation did not change. The majority of bromodeoxyuridine-positive cells co-expressed the immature neuronal marker doublecortin. In addition, the level of neurogenesis in the subventricular zone was not altered. Brain-derived neurotrophic factor mRNA expression was up-regulated following EUK1001 treatment, but no change was observed in expression of camp-responsive element binding protein 1, paired box gene 6, vascular endothelial growth factor alpha, neurogenic differentiation factor 1, and wingless-related mouse mammary tumor virus integration site 3A mRNA. These experimental findings indicated that EUK1001 enhanced proliferation and survival of hippocampal cells, possibly by increasing brain-derived neurotrophic factor expression.
Emergence of Secondary Trigger Sites after Primary Migraine Surgery

Background: Surgical decompression of a migraine headache may unmask headaches originating from secondary sites. A retrospective chart review investigated the incidence and characteristics of secondary trigger sites to identify clinical patterns that could aid in predicting and perhaps reducing postoperative migraines. Methods: One hundred eighty-five charts for migraine patients who underwent surgery at the senior author’s (B.G.) practice were reviewed. Sites from which migraine headaches initiated or occurred independently were considered primary. The sites that were not active at the time of preoperative evaluation but became active after surgery were considered secondary. Bivariate analysis was performed to characterize postoperative migraines. Results: Of 185 patients, 33 (17.8 percent) developed secondary migraine headache trigger sites. Of patients with primary site I (frontal) symptoms, 20.83 percent had site III (septonasal) symptoms unmasked after surgery (versus 7 percent for patients with other primary sites; p = 0.04). Of the patients with site II (temporal) migraines, 17.14 percent had secondary frontal symptoms (versus 5.68 percent; p = 0.04). Primary site II symptoms predicted postoperative site IV (occipital) symptoms (11.43 versus 1.1 percent; p = 0.008), and primary occipital symptoms predicted postoperative temporal symptoms (11.1 versus 2.33 percent; p = 0.04). Conclusions: The authors observed that 17.8 percent of patients develop postoperative migraine headache triggers that are not reported during the initial assessment. Knowledge of secondary migraine emergence patterns, and the presence of some preoperative symptoms, can aid in predicting the migraines that will arise from a new site postoperatively. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.
Strokes restricted to the insular cortex

Objective: To characterize clinically acute insular strokes from four patients with a first ever acute stroke restricted to the insula on MRI. Methods: The authors studied the clinical presentation of four patients with a first ever acute stroke restricted to the insula on MRI. Results: The authors found five main groups of clinical presentations: 1) somatosensory deficits in three patients with posterior insular stroke (two with a transient pseudothalamic sensory syndrome, one with partial distribution); 2) gustatory disorder in a patient with left posterior insular infarct; 3) vestibular-like syndrome, with dizziness, gait instability, and tendency to fall, but no nystagmus, in three patients with posterior insular strokes; 4) cardiovascular disturbances, consisting of hypertensive episodes in a patient with a right posterior insular infarct; and 5) neuropsychological disorders, including aphasia (left posterior insula), dysarthria, and transient somatoparaphrenia (right posterior insula). Conclusion: Strokes restricted to the posterior insula may present with pseudothalamic sensory and vestibular-like syndromes as prominent clinical manifestations, but also dysarthria and aphasia (in left lesions), somatoparaphrenia (right lesions) and gustatory dysfunction and blood pressure with hypertensive episodes in right lesions; we did not find acute dysphagia reported in anterior, insular strokes.
The Psychology of Innovation in Organizations: References

In today’s highly competitive market, organizations increasingly need to innovate in order to survive. Drawing on a wealth of psychological research in the field of creativity, David H. Cropley and Arthur J. Cropley illustrate practical methods for conceptualizing and managing organizational innovation. They present a dynamic model of the interactions among four key components of creativity – product, person, process, and press – that function as building blocks of innovation. This volume sheds new light on the nature of innovative products and the processes that generate them, the psychological characteristics of innovative people, and the environments that facilitate innovation. It also fills a significant gap in the current literature by addressing the paradoxical quality of organizational innovation, which may be both helped and hindered by the same factors. The authors demonstrate that, with proper measurement and management, organizations can effectively encourage individuals to produce and take advantage of novel ideas.
Informality and employment vulnerability: application in sellers with subsistence work

ABSTRACT OBJECTIVE To describe the origin, evolution, and application of the concept of employment vulnerability in workers who subsist on street sales. METHODS We have carried out an analysis of the literature in database in Spanish, Portuguese, and English, without restriction by country. This is a review of the gray literature of government reports, articles, and documents from Latin America and the Caribbean. We have analyzed information on the informal economy, social-employment vulnerability, and subsistence workers. RESULTS AND CONCLUSIONS The concept of informal economy is dispersed and suggested as synonymous with employment vulnerability. As a polysemic term, it generates confusion and difficulty in identifying defined profiles of employment vulnerability in informal subsistence workers, who sell their products on the streets and sidewalks of cities. The lack of a clear concept and profile of employment vulnerability for this type of workers generates a restriction on defined actions to reduce employment vulnerability. The profiles could facilitate access to the acquisition of assets that support their structure of opportunities, facilitating and mediating in the passage from vulnerability to social mobility with opportunities. We propose as a concept of employment vulnerability for subsistence workers in the informal sector, the condition of those who must work by day to eat at night, who have little or no ownership of assets, and who have a minimum structure of opportunities to prevent, face, and resist the critical situations that occur daily, putting at risk their subsistence and that of the persons who are their responsibility, thus making the connection between social and employment vulnerability.