Miracle-dz/UniFAR-FTUs huggingface dataset:
Coagulation Profile in neonates with perinatal asphyxia

Background: Perinatal Asphyxia refers to a condition during the first and second stage of labour in which impaired gas exchange leads to fetal acidosis, hypoxemia and hypercarbia. It accounts for about 23 per cent of the four million newborn deaths worldwide.Methods: To estimate the magnitude of coagulation derangement in babies who suffered birth asphyxia and compare it with non-asphyxiated controls.Results: There were 61.9% and 64 % males in both the groups outnumbering females suggesting that the health care seeking behavior for male children is more than for their female counterparts. Birth weight and mode of delivery are comparable in both the groups. PT and APTT were significantly higher in the asphyxiated babies than in their respective control group. It may be noted , however, that PT and APTT values were higher in the control group also, when compared with the reference values. This may indicate that the hemostatic mechanisms are already compromised in the newborns and perinatal asphyxia further augment the situation tilting it in favour of bleeding. Thrombocytopenia is observed in the asphyxiated group which may be due to placental insufficiency. Severe bleeding is significant in asphyxiated group as compared to the control.Conclusion: Dyscoagulation should be considered in all asphyxiated babies, and they may present with clinically significant bleeding, which may require fresh frozen plasma to restore and maintain their coagulation status.
The Shared and Distinct White Matter Networks Between Drug-Naive Patients With Obsessive-Compulsive Disorder and Schizophrenia

Background: Obsessive-compulsive disorder (OCD) and schizophrenia (SZ) as two severe mental disorders share many clinical symptoms, and have a tight association on the psychopathological level. However, the neurobiological substrates between these two diseases remain unclear. To the best of our knowledge, no study has directly compared OCD with SZ from the perspective of white matter (WM) networks. Methods: Graph theory and network-based statistic methods were applied to diffusion MRI to investigate and compare the WM topological characteristics among 29 drug-naive OCDs, 29 drug-naive SZs, and 65 demographically-matched healthy controls (NC). Results: Compared to NCs, OCDs showed the alterations of nodal efficiency and strength in orbitofrontal (OFG) and middle frontal gyrus (MFG), while SZs exhibited widely-distributed abnormalities involving the OFG, MFG, fusiform gyrus, heschl gyrus, calcarine, lingual gyrus, putamen, and thalamus, and most of these regions also showed a significant difference from OCDs. Moreover, SZs had significantly fewer connections in striatum and visual/auditory cortices than OCDs. The right putamen consistently showed significant differences between both disorders on nodal characteristics and structural connectivity. Conclusions: SZ and OCD present different level of anatomical impairment and some distinct topological patterns, and the former has more serious and more widespread disruptions. The significant differences between both disorders are observed in many regions involving the frontal, temporal, occipital, and subcortical regions. Particularly, putamen may serve as a potential imaging marker to distinguish these two disorders and may be the key difference in their pathological changes.
GMM for Panel Count Data Models

This paper gives an account of the recent literature on estimating models for panel count data. Specifically, the treatment of unobserved individual heterogeneity that is correlated with the explanatory variables and the presence of explanatory variables that are not strictly exogenous are central. Moment conditions are discussed for these type of problems that enable estimation of the parameters by GMM. As standard Wald tests based on efficient two-step GMM estimation results are known to have poor finite sample behaviour, alternative test procedures that have recently been proposed in the literature are evaluated by means of a Monte Carlo study.
A retrospective study to assess prevalence of gestational diabetes mellitus among those who delivered in Saveetha Medical College and Hospital

Background: Gestational diabetes mellitus (GDM) defined as any degree of carbohydrate intolerance with onset or first recognition during pregnancy contributes to about 90% of diabetes complicating pregnancy. GDM imposes risks for both mother and fetus, some of which continues throughout the life of mother and child. The objective of the present study was to determine the prevalence of gestational diabetes mellitus and the associated risk factors among those who delivered in Saveetha medical college and hospital.Methods: A retrospective study was conducted by analysing the medical records of the patients who were admitted in the Department of Obstetrics and Gynaecology over a period of 1 year at Saveetha medical college and hospital, Chennai, Tamil Nadu, India. The diagnosis of GDM was made mainly by 75gm one step oral glucose tolerance test (OGTT). The guideline endorses 2-hours 75-gm OGTT, irrespective of last meal timings with a cut off value of ≥140 mg/dl. All data was analysed by simple descriptive statistics and percentage method.Results: In the present study, the total number of deliveries for 1 year from April 2018 - March 2019 were 511 and among those the total number of antenatal mothers with GDM who delivered were 46. Therefore the prevalence of GDM was calculated to be 9% or 90 per thousand deliveries. In the present study, 37 (65.1%) pregnant women of GDM group were seen in the age group of above 25 years, 27 (58.59%) were multiparous, 25(54.25%) pregnant females with GDM were found to have overweight and obese out of 46 cases.Conclusions: Our current study concludes the Prevalence of GDM in Saveetha Medical College Hospital is 9% between April 2018-March 2019. We have identified the following risk factors for developing GDM: multiparity≥2; previous history of diabetes mellitus; age ≥ 25; BMI ≥25; and family history of diabetes.
Cycle Extensions in BIBD Block‐Intersection Graphs

A cycle C in a graph G is extendable if there is some other cycle in G that contains each vertex of C plus one additional vertex. A graph is cycle extendable if every non‐Hamilton cycle in the graph is extendable. A balanced incomplete block design, BIBD (v,k,λ) , consists of a set V of v elements and a block set B of k‐subsets of V such that each 2‐subset of V occurs in exactly λ of the blocks of B . The block‐intersection graph of a design D=(V,B) is the graph GD having B as its vertex set and such that two vertices of GD are adjacent if and only if their corresponding blocks have nonempty intersection. In this paper, we prove that the block‐intersection graph of any BIBD (v,k,λ) is cycle extendable. Furthermore, we present a polynomial time algorithm for constructing cycles of all possible lengths in a block‐intersection graph.
Brand Equity through Customer Engagement in Social Media: A Critical Review

In the context of present competitive environment, brands are the crucial drivers regarding product purchase, revenue and profit generation. Hence, Brands constitute an important intangible asset for the firms. Simultaneously, with the advent of internet, IT services and social media network information services, consumers are turning away from traditional sources of communication such as press, radio, television as used by various companies in past. Now a days, consumers take their decisions largely based on their trust on friends, family and online product reviews, and all of these are found in the social media network environment. Similarly, various authors highlighted brand identity approach for creating brand equity as employee constitute the original source of brand equity. Thus, present research gives important theoretical insights on the development of brand equity through customer engagement in social media. This research tries to assimilate the five dimensions of Aaker's well-known conceptual framework of brand equity with the process of customer engagement in social media along with brand identity approach through employee engagement and thus, an integrated conceptual framework has been developed.
A social safety net? Rejection sensitivity and political opinion sharing among young people in social media

One reason why people avoid using social media to express their opinions is to avert social sanctions as proposed by the spiral of silence theory. We here elaborate on individual-level sensitivity to social rejection in relation to voicing political opinions on social media sites. Given the uncertainty about sharing political views in social media, and the fact that social acceptance, or rejection, can be easily communicated through, for instance, likes, or a lack of likes, we argue that rejection sensitive individuals are less likely to share political information in social media. Combining an analysis of unique survey data on psychological characteristics and online political activity with focus group interviews with Swedish youth supports our argument, showing that rejection sensitive individuals are less inclined to engage politically in social media. The results extend on previous research by establishing the role of rejection sensitivity in political engagement in social media.
The Use of Bituminous Subballast on Future High-Speed Lines in Spain

The development of structural solutions for high-speed or very high-speed tracks that minimize total life cycle costs of the system is a key issue to improve the operational profitability of new investments. In opposition to conventional ballasted tracks, slab track solutions can be a cost-effective solution, but only in the cases where the benefits due to the increase in track availability and the reduction of track maintenance offsets its much higher construction costs. In the cases where such investment is not feasible, it is worth to evaluate possible structural improvements to ballasted track that allow reducing its maintenance needs without increasing too much its construction costs. This paper evaluates the design requirements and the impact of improving conventional high-speed ballasted tracks by using a bituminous subballast layer. It is divided into two main parts: first the design requirements of the structural solutions with bituminous subballast and its possible benefits on high-speed track deterioration, and secondly the evaluation of the economic impact, in terms of construction costs, of using this structural solution material in future Spanish high-speed lines.
The Effect of Leverage on Firm Value and How The Firm Financial Quality Influence on This Effect

This paper applied the Generalized Method of Moment (GMM) to estimate the effect of leverage on firm values and contextual variables influencing on this relationship. Using 645 companies listed in Taiwan Securities Exchange (TSE) from 2000-2009. The empirical results show as follows: Firstly, the values of leveraged firm are greater than that of an unleveraged firm if we don’t consider bankruptcy probability. Secondly, If we consider the benefit and cost of debt simultaneously, the leverage is significantly positively related to the firm value before reaching firm’ optimal capital structure. Thirdly, the positive influence of leverage to the firm value tends to be stronger when the firm financial quality is better (i e., the greater Z-score). This finding can provide the insight into the firm debt finance decision to maximize the firm value.
An evaluation of Alberta pharmacists’ practices, views and confidence regarding prescription drug abuse and addiction within their practice setting

Background: Pharmacists play an important role in managing patients with prescription drug abuse and addiction (PDAA). The objective of this study was to explore Alberta pharmacists’ practices, views and confidence in the management of patients at risk of or living with PDAA in their practice setting. Methods: A 26-question online questionnaire was distributed to 4261 pharmacists across Alberta, of whom 656 (15%) participated. The questionnaire consisted of 17 multiple-choice, 6 multipart and 3 free-response questions. Questionnaire responses were collected and analyzed in Qualtrics. Results: Sixty-six percent (n = 408) of pharmacists indicated that PDAA was prevalent in their practice setting, with 55% (n = 340) of respondents encountering more than 6 patients with suspected or known PDAA a month. Thirty-five percent (n = 198) of pharmacists indicated they were moderately confident at identifying patients with potential PDAA. However, 41% (n = 235) of the pharmacists indicated that they only discuss PDAA with identified patients less than half of the time. Pharmacists lacked confidence in their ability to discuss PDAA treatment options with their patients as well as collaborate with addiction treatment facilities. Lack of training or knowledge in PDAA (48%) and uncertainty of how to initiate discussion or effectively communicate with patients about PDAA (39%) were identified as barriers that significantly or very significantly hindered respondents from managing PDAA in their practice. Conclusions: Although many pharmacists are moderately confident in identifying patients with potential PDAA, several barriers hinder intervention. Providing pharmacists with additional training and resources may better equip them to manage PDAA within their practice settings. Can Pharm J (Ott) 2019;152:xx-xx.
Analysis of Oxidative Stress in Chronic Exposure to Petroleum Hydrocarbons in Karnataka, India

Background:Several studies have reported the toxicological implications of inhalation of petroleum hydrocarbon fumes in animal models. But, there is certainly little or no documentation of the exposure to petroleum hydrocarbon fuel on oxidative stress levels in humans, unlike the pulmonary physiology. The present study was carried out to evaluate the effects of constituents of the hydrocarbon fuels on oxidative stress levels of the petrol fillers and tanker drivers. Methods: The study involved 165 males divided into three groups were the petrol fillers, tanker drivers and the controls. Case control data set was established wherein the control subjects are not exposed to hydrocarbon fuels with similar age. Serum samples of the subjects were collected and subjected for various biochemical assays. The enzymatic antioxidants such as superoxide dismutase, malondialdehyde a byproduct of lipid peroxidation and total antioxidant capacity of the individuals along with non-enzymatic antioxidant Vitamin A was estimated. Results: The results showed a no significant differences for age, body mass index, superoxide dismutase and levels of Malondialdehyde and total antioxidant capacity. But on the other hand, there is significant changes observed for total antioxidant capacity and vitamin A when exposed group is compared with control subject. Conclusion: It is evidential from the present study that prolonged exposure to petroleum hydrocarbon fumes leads to an increase in their oxidative stress in turn resulting broad spectrum of diseases. Hence, there is a raised need for public awareness about the health hazards in order to enable petrol attendants.
Analysis of Risk Factors for Patients with Liver Cirrhosis Complicated with Spontaneous Bacterial Peritonitis

Background: We aimed to explore risk factors for patients with liver cirrhosis complicated with spontaneous bacterial peritonitis (SBP). Methods: The clinical data of 195 patients with liver cirrhosis complicated with SBP (study group), admitted from March 2014 to March 2018 in Tianjin Medical University General Hospital, Tianjin, China and 195 patients without liver cirrhosis complicated with SBP (control group) were retrospectively analyzed. Clinical manifestations of patients and laboratory findings were analyzed. Univariate and multivariate Logistic regression analysis were used for independent risk factors for the occurrence of SBP. Results: There were significant differences in patients between study group and control group in Child-Pugh classification, peripheral blood white blood cell (WBC), serum C-reactive protein (CRP), serum total bilirubin (TBil), ascites WBC, ascites albumin (ALB), and the ratio of complicated with upper gastrointestinal hemorrhage, hepatorenal syndrome, hepatic encephalopathy and hyponatremia (P<0.01); Logistic regression analysis found that Child-Pugh classification, serum CRP, ascites WBC, ascites ALB, upper gastrointestinal hemorrhage, hepatorenal syndrome, hepatic encephalopathy and hyponatremia were related to the occurrence of SBP; and Child-Pugh classification, ascites ALB, upper gastrointestinal hemorrhage, hepatorenal syndrome and hyponatremia were its independent risk factors. Conclusion: Child-Pugh classification, ascites ALB, upper gastrointestinal hemorrhage, hepatorenal syndrome and hyponatremia are independent risk factors for the occurrence of liver cirrhosis complicated with SBP. Cautions should be raised for patients with liver cirrhosis for this. In the early stage, we should make effective antibiotic anti-bacterial infection program, actively prevent and control the occurrence of SBP, improving the survival rate of patients.
Seed Selection and Social Coupon Allocation for Redemption Maximization in Online Social Networks

Online social networks have become the medium for efficient viral marketing exploiting social influence in information diffusion. However, the emerging application Social Coupon (SC) incorporating social referral into coupons cannot be efficiently solved by previous researches which do not take into account the effect of SC allocation. The number of allocated SCs restricts the number of influenced friends for each user. In the paper, we investigate not only the seed selection problem but also the effect of SC allocation for optimizing the redemption rate which represents the efficiency of SC allocation. Accordingly, we formulate a problem named Seed Selection and SC allocation for Redemption Maximization (S^3CRM) and prove the hardness of S^3CRM. We design an effective algorithm with a performance guarantee, called Seed Selection and Social Coupon allocation algorithm. For S^3CRM, we introduce the notion of marginal redemption to evaluate the efficiency of investment in seeds and SCs. Moreover, for a balanced investment, we develop a new graph structure called guaranteed path, to explore the opportunity to optimize the redemption rate. Finally, we perform a comprehensive evaluation on our proposed algorithm with various baselines. The results validate our ideas and show the effectiveness of the proposed algorithm over baselines.
Speaker-Phonetic I-Vector Modeling for Text-Dependent Speaker Verification with Random Digit Strings

SUMMARY This paper proposes a speaker-phonetic i-vector modeling method for text-dependent speaker veriﬁcation with random digit strings, in which enrollment and test utterances are not of the same phrase. The core of the proposed method is making use of digit alignment information in i-vector framework. By utilizing force alignment information, veriﬁcation scores of the testing trials can be computed in the ﬁxed-phrase situation, in which the compared speech segments between the enrollment and test utterances are of the same phonetic content. Speciﬁcally, utterances are segmented into digits, then a unique phonetically-constrained i-vector extractor is applied to obtain speaker and channel variability representation for every digit segment. Probabilistic linear discriminant analysis (PLDA) and s-norm are subsequently used for channel compensation and score normalization respectively. The ﬁnal score is obtained by combing the digit scores, which are computed by scoring individual digit segments of the test utterance against the corresponding ones of the enrollment. Experimental results on the Part 3 of Robust Speaker Recognition (RSR2015) database demonstrate that the proposed approach signiﬁcantly outperforms GMM-UBM by 52 : 3% and 53 : 5% relative in equal error rate (EER) for male and female respectively. key words: speaker veriﬁcation, text-dependent, speaker-phonetic, random digit strings
An argument for purely altruistic movement

Classical syntactic theory was designed to ensure that raising would be able to proceed out of infinitival clauses, but not out of finite clauses. However, it has since become clear that a number of languages in fact allow raising out of finite clauses (hyperraising). This paper argues that the Mexican isolate P’urhepecha—more specifically, the variety spoken on the island of Janitzio on Lake Pátzcuaro—allows hyperraising to object (cf. Bruening 2002, Tanaka 2002, Halpert & Zeller 2015, Deal 2016), and develops an analysis of this phenomenon on which it involves two steps of purely altruistic (target-driven) movement—i.e., movement driven exclusively by a featural requirement of an attracting head. Alternative analyses of the phenomenon based on Greed (Chomsky 1995a, Bošković 2007, a.o.) or Labeling (Chomsky 2013, 2015, a.o.) are considered and shown to face serious problems. P’urhepecha hyperraising to object, then, sheds light on the driving force for movement: it provides an argument for Enlightened Self-Interest (Lasnik 1995, 2003, a.o.), the hypothesis that movement may be driven by a feature either of the moving element or (as here) of an attracting head. The phenomenon also narrows down the space of possibilities for understanding the A/Ā-distinction.
Pharmaceutical Care in the Community Pharmacies of Saudi Arabia: Present Status and Possibilities for Improvement

Pharmaceutical care can be given in all settings: The community, hospitals, long-term care, and the clinic. However, published literature indicates that there is a substantial barrier to implementing pharmaceutical care programs in community pharmacies. This review was conducted to discover gaps and limitations in pharmaceutical care services in community pharmacies in the Kingdom of Saudi Arabia (KSA). We searched PubMed and other available scientific website databases using the following key words to retrieve the relevant articles: Community Pharmacy, Healthcare System, Pharmaceutical Care, KSA. Two authors independently screened the titles and abstracts of promising articles. They discarded irrelevant studies and retained studies, and reviews that held the promise of relevant data or information. The review revealed that only one out of the four studies conducted in KSA retrieved by the authors reported pharmaceutical care service other than dispensing. The same results were reported in other studies conducted in some developing countries. All pharmaceutical care services were reported in studies conducted in Europe. The authors came to the conclusion that in KSA, dispensing of medicines is the dominant service provided by community pharmacists and that there was very limited if not a total absence of other pharmaceutical care services.