Miracle-dz/UniFAR-FTUs huggingface dataset:
Audit Report Information Content and Auditor Economic Independence in Credit Decisions: An Experimental Investigation

This study examines whether loan officers’ perception of auditor economic independence affects audit report information content. We conducted an experiment where 80 experienced loan officers from one of the largest European commercial banks were provided with a request for financing from a hypothetical client. Type of audit report and economic independence in terms of non-audit services were manipulated in a 2 (unqualified but modified vs. a going concern audit report) × 2 (low economic dependence vs. high economic dependence) between-subjects design. According to recent research on audit report information content, our findings support that loan officers view a qualified audit report as a first-order mechanism/filter that acts as an early warning system. In addition, our results also suggest that auditor economic dependence is viewed as a second-order mechanism that only activates loan officers’ professional skepticism when the first-order mechanism has not released a warning signal.
OK-432 therapy for lymphangiomas.

OBJECTIVE To assess the efficacy of OK-432 sclerotherapy in the treatment of lymphangiomas. DESIGN Nonrandomized trial; follow-up, 4 to 29 months. SETTING Academic tertiary referral medical center. PATIENTS Six children with presumed lymphangiomas; age range at initial treatment, 1 month to 7 years 10 months. INTERVENTION Fluoroscopically guided cyst aspiration, cystography, and injection of OK-432. OUTCOME MEASURES Clinical and radiographic comparisons before and after therapy. RESULTS Complete response in 2 macrocystic lymphangiomas; no response in 3 microcystic lymphangiomas; and no response in 1 venous malformation. CONCLUSION OK-432 sclerotherapy may be effective treatment for macrocystic lymphangiomas.
Online behaviour of luxury fashion brand advocates

Purpose – Over the past few years online fashion communities have proliferated becoming an increasingly powerful forum for user-generated content, and consequently, the fashion industry has shown great interest in such communities. The purpose of this paper is to review and analyse brand advocacy behaviour within luxury brand accessory forums: to analyse the role these communities play in influencing purchase intention; assessing their contribution to fashion brand love. Design/methodology/approach – The study adopted a netnographic approach to the phenomenon of online luxury accessory communities. The research reports observational data including blog texts and audience comments for four popular forums: The Purse Forum, The Fashion Spot, The Bag Forum (TBF) and Shoe Forum (SF). Although the forums are open to all and are designed to be internationally relevant; the observations were conducted from a base in the UK. Findings – Findings indicate that informants display some unifying characteristics cluster.
Endogenous Hormones Levels and Csexpansin 10 Gene Expression in the Fruit Set and Early Development of Cucumber

Fruit set and early development depends on endogenous hormone levels and gene expression related to fruit growth and development in cucumber (Cucumis sativus). In this study, the growth and development of cucumber ovaries and young fruits, endogenous hormones levels, and Csexpansin 10 (CsEXP 10) gene expressions in pollinated fruits and unpollinated ovaries were studied from -2 to 6 days post anthesis (DPA). The results showed that the fruit diameter and length, single fruit weight, endogenous hormone levels, and CsEXP 10 gene expression levels were all higher in pollinated fruits than in unpollinated ovaries, and CsEXP 10 gene expression levels were positively correlated with indole-3-acetic acid (IAA), but negatively correlated with gibberellic acid (GA3) and abscisic acid (ABA). This suggests that pollination may stimulate the fruit set and development by inducing increases in endogenous hormone levels and CsEXP 10 gene expression, and the CsEXP 10 gene may be downregulated by GA3 and ABA.
Quality of financial reports: Evidence from the Tunisian firms

This paper studies the effect of the quality of annual reports on investor’s decisions in the Tunisian financial market. We measure the qualities of content and form of financial reports and their effects on investors’ decisions, particularly on stock prices. We used a sample of 175 publications between 2006 and 2010. Our results provide strong evidence that the content’s effect is higher than the form’s effect in making decisions.
Employee Engagement- A Corporate Boon 10 Ways for Effective Engagement

This study examines the relationship between Organization- Based Self-Esteem24 and the three dimensions of burnout i.e. emotional exhaustion, depersonalization and reduced personal accomplish-ment.20 Our hypothesis was that the three dimensions of burnout would have a negative impact on OBSE. Data collected from 215 employees working in a heavy manufacturing plant in the Midwestern part of the United States supported this hypothesized relationship. The organizational implications of these results and directions for further research are discussed.
‘If they have a girlfriend, they have five girlfriends’: Accountability and sexism in volunteer workers’ talk about HIV/AIDS in a South African health setting

Significant challenges remain in tackling the global HIV/AIDS epidemic. Effective action requires both appropriate policy at a global level and informed practice on the local level. Here, we report how workers in a project in Johannesburg, South Africa, make sense of HIV transmission. Discourse analysis of data from interviews with 63 participants shows that project workers routinely attribute transmission to men’s sexual relationships with multiple female partners. This explanation is so pervasive that it renders invisible other routes to transmission. Absence of consideration of other routes to infection potentially restricts front-line practice, so hindering local attempts to tackle HIV/AIDS.
The detection and phylogenetic analysis of porcine deltacoronavirus from Guangdong Province in Southern China

Porcine deltacoronavirus (PDCoV) is a newly discovered coronavirus that causes diarrhoea, vomiting and dehydration in sucking and nursing piglets. It was first reported in Hong Kong in 2012 and has since been discovered in the United States, Canada, South Korea, mainland China, Thailand and Laos. PDCoV has been experimentally proved to lead to diarrhoea in swine and it was detected positive in pigs in Guangdong, southern China. In our study, 252 faecal and intestinal samples from sucking piglets and sows with diarrhoea were surveyed for common enteric viruses. We found a prevalence of PDCoV (21.8%), porcine epidemic diarrhoea virus (65.5%), transmissible gastroenteritis virus (0%), rotavirus group A (25.0%) and porcine kobuvirus (68.7%). We isolated 13 PDCoV strains and discovered that PDCoV infections were often co-infections with kobuvirus rather than the commonly linked porcine epidemic diarrhoea virus. Phylogenetic analysis of S gene and N gene revealed that 11 of 13 PDCoV strains belonged to Chinese lineage. As for the left two strains, one single strain (CHN-GD16-05) belonged to American and Korean lineages while another strain (CHN-GD16-03) was similar to a Thai strain, but only in the S gene. This suggested a possible recombination event between the Thai and the newly described Chinese strain.
Inhibition of Dipeptidyl Peptidase IV With Sitagliptin (MK0431) Prolongs Islet Graft Survival in Streptozotocin-Induced Diabetic Mice

OBJECTIVE—Dipeptidyl peptidase-IV (DPP-IV) inhibitors have been introduced as therapeutics for type 2 diabetes. They partially act by blocking degradation of the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), thus increasing circulating levels of active hormones. In addition to their insulinotropic actions, GLP-1 and GIP also promote β-cell proliferation and survival, and DPP-IV inhibitors exert similar effects in rodent type 2 diabetes models. The study objective was to establish whether DPP-IV inhibitor treatment prolonged survival of transplanted islets and to determine whether positron emission tomography (PET) was appropriate for quantifying the effect of inhibition on islet mass. RESEARCH DESIGN & METHODS—Effects of the DPP-IV inhibitor MK0431 (sitagliptin) on glycemic control and functional islet mass in a streptozotocin (STZ)-induced type 1 diabetes mouse model were determined with metabolic studies and microPET imaging. RESULTS—The type 1 diabetes mouse model exhibited elevated plasma DPP-IV levels that were substantially inhibited in mice on an MK0431 diet. Residual β-cell mass was extremely low in STZ-induced diabetic mice, and although active GLP-1 levels were increased by the MK0431 diet, there were no significant effects on glycemic control. After islet transplantation, mice fed normal diet rapidly lost their ability to regulate blood glucose, reflecting the suboptimal islet transplant. By contrast, the MK0431 group fully regulated blood glucose throughout the study, and PET imaging demonstrated a profound protective effect of MK0431 on islet graft size. CONCLUSIONS—Treatment with a DPP-IV inhibitor can prolong islet graft retention in an animal model of type 1 diabetes.
Rethinking 3D visualisation : from photorealistic visual aid to multivocal environment to study and communicate cultural heritage

This research presents the issue of opacity in 3D visualisations of cultural heritage and explains how it prevents 3D technologies from being used to their full extent in an academic context. The impossibility to assess the provenance of the sources, cite references or identify individual contributions make the majority of available 3D models closer to mere illustrations than tools for the study and understanding of the past, regardless the amount of research that has informed the creation of the visual output. An analysis of some of the existing strategies of documentation of 3D visualisations highlights the current lack of a standard, or even a common language, that would make such documentations comparable and cross searchable. This work suggests the use of a simple, sustainable and well-established technology as Linked Open Data, together with a tailored domain ontology, as a possible approach. The use of the synthetic and formalised vocabulary of an ontology, with its classes and properties, is used experimentally, as a proof of concept, to document the 3D visualisation of an ancient building, the Iseum in Pompeii, and to connect each part of the model to the documents that have been used as sources. The proof of concept also shows how the application of LOD technology can, potentially, change the way 3D visualisation is used in academia, not only making 3D models documented and, therefore, closer to a scientific publication, but, also, encouraging exchange and reuse of data and facilitating preservation. The thesis discusses the rationale behind the creation of the ontology, its application to the documentation of a complex 3D model and its contribution towards a collaborative and transparent use of 3D technologies in academia. The 3D models, the ontology, and the text are equally important components of this work.
Immunohistochemical localization of androgen receptor in mouse testicular germ cells during fetal and postnatal development

Determination of the cellular distribution of the androgen receptor (AR) in testicular cells is necessary for understanding the mode of AR action in the testis. We here investigated immunohistochemically the localization of AR by use of anti‐human AR polyclonal antibody NH27, with special reference to the AR in germ cells in the developing mouse testis.
Recommendations for a nomenclature system for human gene mutations

This document has been written in response to meetings on “Locus-specific Mutation Databases” held on March 24, 1996 in Heidelberg, Germany and “Mutation Databases” on October 29, 1996 in San Francisco, California. As a chairperson of the Nomenclature committee, the first author had accepted the task of preparing and circulating a document with recommendations for debate, further discussions and most importantly for final approval/acceptance at the October 1996 meeting in San Francisco. Four drafts of this document (August 5, 1996, September 5, 1996, November 29, 1996, and May 29, 1997) were distributed to a number of investigators, the majority of whom were co-authors in the Beaudet et al, 1996 and Beutler et al, 1996 papers. This document contains modifications according to their suggestions, opinions and criticisms. Furthermore, many colleagues had offered suggestions, criticisms, and ideas through electronic communication. During the October 1996 meeting in San Francisco, there was a sufficient discussion of these recommendations and it was agreed that another, further modified draft of the document would be posted on the “World Wide Web” for final debate for a period of several weeks. This present document is also the result of all of these discussions and was approved during that October 27, 1997 meeting in Baltimore. Two manuscripts were recently published in “Human Mutation” that contain mutation nomenclature recommendations (Beaudet et al., 1996 and Beutler et al., 1996). These documents present the views of the authors after discussions during the October 19, 1994, Montreal, and the October 24-25, 1995 Minneapolis meetings. Other previously published papers/ letters on nomenclature issues include the following: Beaudet & Tsui, 1993; Beutler, 1993; Antonarakis & McKusick, 1994. It is obvious that the most unambiguous nomenclature system is that based on genomic DNA. Even Received 5 September 1997; accepted 3 October 1997.
India-ASEAN Free Trade Agreement: A Sectoral Analysis

This study investigates the sectoral dimensions of India–ASEAN Free Trade Agreement as a result of tariff liberalization. This study reveals that both India and ASEAN gains in terms of welfare while a term of trade for India deteriorates. The present study reveals that processed food products, grain crops, textile and wearing apparel, light manufacturing and heavy manufacturing sectors are expected to be affected significantly and differently. However, results indicate a surge of ASEAN’s exports of processed food items, agricultural products and fisheries which might have adverse impact on employment and wages of Indian working class. This study also revealed that the present FTA will have adverse impact on trade balance and the revenue losses for India which might affect public health, education and government procurement holding for a significant share of national budgets having multiple development dimensions.
The VKORC1 gene homozygous polymorphism is markedly higher inCrimean Congo Hemorrhagic Fever patients.

In Crimean-Congo Hemorrhagic Fever (CCHF), the main target of the virus is endothelial cells, monocytes and hepatocytes. The virus in these cells leads to the development of capillary vessels dysfunction, which induces clinical and pathological changes during the disease. Increase in capillary permeability and coagulation dysfunction constitute a tendency to bleed. In the current study, we aimed to investigate the relationship between VKORC1 and bleeding tendency in CCHF. Forty-eight consecutive patients with a laboratory-confirmed diagnosis of CCHF were treated with blood products, and 37 healthy volunteers as the control group were prospectively enrolled into the study. The DNA was obtained from each sample using PCR amplification method, and VKORC1 1639 G>A gene polymorphisms were scanned in the DNA samples. In CCHF group of patients with bleeding VKORC1 gene were analyzed. Normal genotype was detected in 5 (22.7%) patients, homozygote mutation was detected in 2 (9.1%) patients and heterozygote mutation was detected in 15 (68.2%) patients, respectively. Furthermore, the G allele frequency was statistically higher in study group (51 [53%] vs. 27 [36%]) (p<0.005). It seems to be that VKORC1 gene A allele frequencies saliently higher in CCHF. This might be associated with increased bleeding risk in CCHF. Analyzing of VKORC1 gene polymorphisms could help in the risk stratification of patients with CCHF.
Fascin Expression in Human Embryonic, Fetal, and Normal Adult Tissue

This study investigates the distribution of fascin in human embryonic, fetal, and normal adult tissues. Tissue microarray technology was used to perform immunohistochemical experiments on human embryos and fetuses at 4–22 weeks of gestation and adult specimens. Fascin was widely expressed in the nervous system. At 4 weeks of gestation, fascin was present in the neural tube. At 8–12 weeks of gestation, homogenous gene expression was seen in cells of the cerebellum and gastrointestinal tract. In later developmental stages and in adults, Purkinje cells of the cerebellum and glandular epithelium of the gastrointestinal tract showed no expression. Fascin was expressed in the cortex and medulla of the adrenal gland at 8–12 weeks of gestation, whereas immunoreactivity decreased from the zona glomerulosa through the zona reticularis and was essentially negative in the adrenal medulla of adults. Significant expression of fascin was seen throughout development in neurons, follicular dendritic cells of lymphoid tissue, basal layer cells of stratified squamous epithelia, mesenchyme, and vascular endothelial cells. Simple columnar epithelia of the biliary duct, colon, ovary, pancreas, and stomach were all negative for fascin expression. These results show that expression of fascin is time specific and highly tissue specific. Parallels between fascin expression in embryogenesis and carcinogenesis are discussed.
Human alkaline phosphatase. Immunochemical identification of organ-specific isoenzymes.

Abstract The antigenic distinctiveness of individual organ-specific isoenzymes of human alkaline phosphatase was shown by immunochemical means. A two-step method involving two separate antigen-antibody reactions was utilized to identify and measure the isoenzymes. The first reaction consisted of reaction of the isoenzyme with its antiserum; the second reaction consisted of precipitating the enzyme-antibody complex with anti-γ-globulin. The second reaction was necessary because the enzyme was neither inhibited nor precipitated by specific antibody. By this method, individual isoenzymes could be identified from mixtures of isoenzymes. The results clearly show that antibody to liver phosphatase and antibody to placental phosphatase were specific for their respective homologous antigens, and did not react with alkaline phosphatase from bone, neutrophils, kidney, or intestine. Thus, there are at least three antigenic types of alkaline phosphatases: one derived from liver, one from placenta, and one or more from other organs.
Bovine Coronavirus Detection in a Collection of Diarrheic Stool Samples Positive for Group A Bovine Rotavirus

ABSTRACT Neonatal diarrhea is an important cause of economic losses for cattle farmers. The main viral etiologies of enteric diseases are group A rotaviruses (GARV) and the bovine coronavirus (BCoV). Although both viruses infect calves of the same age, the occurrence of mixed infections is still under studied. The present study describes the co-infection of BCoV and GARV in stool samples. Forty-four diarrheic fecal samples from calves up to 60 days old that had previously tested positive for GARV by SS-PAGE were analyzed using semi-nested PCR for BCoV. A product with 251 bp of the BCoV nucleoprotein gene was amplified in 15.9% (7/44) of the samples, demonstrating that co-infection is not an unusual event. These results reinforce the need for testing for both GARV and BCoV, even in fecal samples that previously tested positive for one virus. Key words: calf, diarrhea, BCoV, rotavirus, SN-PCR, co-infection * Author for correspondence: alfieri@uel.br INTRODUCTION Neonatal diarrhea is one of the main causes of calf mortality worldwide. The disease results in major economic losses in many dairy and beef cattle herds that result from treatment costs and calf deaths. Calf diarrhea is considered to be a multi-factorial disease. Several environmental, management-related, nutritional, and physiological factors may occur either alone or in synergy with different infectious agents such as protozoans, bacteria, and/or viruses. In calves, bovine group A rotavirus (GARV) and bovine coronavirus (BCoV) are the viruses most commonly associated with neonatal diarrhea and it is not unusual that both viruses can concomitantly infect calves (Snodgrass et al ., 1986; Holland, 1990; Alfieri et al ., 2006; Oliveira Filho et al ., 2007). Rotaviruses belong to the Reoviridae family. They have icosahedral symmetry and a non-enveloped capsid formed by three concentric layers of protein that is 70-90 nm in diameter. The rotavirus genome is composed of 11 double-stranded RNA segments (dsRNA). Based on the common group antigen (VP6 protein), rotaviruses are classified antigenically into seven serogroups (A-G). The co-migration of genomic segments 7, 8, and 9 in polyacrylamide gel electrophoresis (PAGE) is an important characteristic of group A rotaviruses (Estes, 1996). Several techniques have been developed to diagnose bovine GARV by detecting the viral
Effect of Hygrophila spinosa in ethylene glycol induced nephrolithiasis in rats

Objective: Hygrophila spinosa (Acanthaceae) is traditionally used to treat urinary calculi. The present study aimed to evaluate the antiurolithiatic activity of methanolic extract of Hygrophila spinosa (Acanthaceae) in ethylene glycol induced nephrolithiasic rats. Materials and Methods: Methanolic extract of Hygrophila spinosa (HSME) (250 and 500 mg/ kg body weight) was administered orally to male Wistar albino rats. Ethylene glycol (EG) was used to induce nephrolithiasis. The parameters studied included water intake, urinary volume, urinary pH, urinary and kidney oxalate and calcium, urinary magnesium and serum uric acid. Results: Ethylene glycol feeding resulted in hyperoxaluria as well as increased renal excretion of calcium and serum uric acid along with decreased excretion of urinary magnesium. Treatment with HSME significantly reduced the elevated urinary oxalate, urinary calcium and serum uric acid with increase in reduced urinary magnesium. Ethylene glycol feeding also resulted in increased levels of calcium and oxalate in kidney which was decreased after the treatment with HSME. The increased deposition of stone forming constituents in the kidneys of ethylene glycol treated rats was significantly lowered by treatment with HSME. Conclusion: The results indicate that the aerial parts of Hygrophila spinosa are endowed with antiurolithiatic activity, thereby justifying its traditional claim.
Taxanes for breast cancer during pregnancy: a systematic review.

The co-occurrence of breast cancer and pregnancy is an important issue for the forthcoming years, given the trend for women to postpone childbearing [1]. Although the use of doxorubicinand epirubicin-based regimens appear quite safe in the second and third trimesters of pregnancy [2, 3], little is known on the safety of taxanes, with only 14 cases found in our literature review 2 years ago [1]. We aimed to collect updated data on the safety of taxanes in pregnant patients, and therefore carried out a systematic review of the English literature by search of Pubmed, Embase, and Web of Knowledge, using the search terms ‘paclitaxel AND pregnancy’, ‘docetaxel AND pregnancy’, and ‘taxanes AND pregnancy’. Only papers published in English from 1990 to 15 September 2009 were included. Twenty-three publications were identified [1, 4–12], describing 40 women and 42 neonates (two gemellar pregnancies). Paclitaxel was administered in 21 cases, docetaxel in 16 cases, and both drugs in 3 cases. Except for two cases [11, 13], taxanes were administered concomitantly or sequentially with other cytotoxic agents, mostly anthracyclines, cyclophosphamide, and platinum derivatives. Twenty-seven patients had breast cancer, 10 had ovarian cancer, and 3 had non-small-cell lung cancer. The 40 cases are summarized in Table 1. Docetaxel was administered during the first trimester