Miracle-dz/UniFAR-FTUs huggingface dataset:
Biomechanical Rationale for Development of Anatomical Reconstructions of Coracoclavicular Ligaments after Complete Acromioclavicular Joint Dislocations

Background Surgical treatments of complete acromioclavicular joint dislocations replace or reconstruct the coracoclavicular ligaments with a single structure and do not account for the anatomical variance of each ligament in the design. Purpose To evaluate the cyclic behavior and structural properties of an anatomic tendon reconstruction of the coracoclavicular ligament complex after a simulated acromioclavicular joint dislocation. Study Design Controlled laboratory study. Methods Cyclic loading followed by a load-to-failure protocol (simulated dislocation) of the normal coracoclavicular ligament complex was performed and repeated after an anatomic reconstruction on the same specimen (n = 9). The anatomical reconstruction consisted of a semitendinosus tendon that replicated the direction and orientation of both the trapezoid and conoid ligaments. Results The coracoclavicular ligament and anatomical reconstruction complexes had clinically insignificant (<3 mm) permanent elongation after cyclic loading. The stiffness and ultimate load of the coracoclavicular ligament complex (60.8 ± 12.2 N/mm and 560 ± 206 N) were significantly greater than for the anatomical reconstruction complex (23.4 ± 5.2 N/mm and 406 ± 60 N), respectively (P < .05). Further analysis of the complexes revealed a 40% decrease in the bending stiffness of the clavicle after the simulated dislocation and failure of the normal coracoclavicular ligament complex (P < .05), which contributed to the diminished properties of the anatomic reconstruction. Conclusions The low level of permanent elongation after cyclic loading suggests that the anatomic reconstruction complex could withstand early rehabilitation; however, the decrease in the structural properties and stiffness of the clavicle should be considered in optimizing the anatomic reconstruction technique. Clinical Relevance Despite the differences compared to the normal coracoclavicular ligament complex, the anatomical reconstruction complex more closely approximates the stiffness of the coracoclavicular ligament complex than current surgical constructs, and the incorporation of biological tissue could improve the overall structural properties with healing.
Altered Visual Adaptation to Body Shape in Eating Disorders: Implications for Body Image Distortion

Previous research has shown that after adapting to a thin body, healthy participants (HP) perceive pictures of their own bodies as being fatter and vice versa. This aftereffect might contribute to the development of perceptual body image disturbances in eating disorders (ED). In the present study, HP and ED completed a behavioral experiment to rate manipulated pictures of their own bodies after adaptation to thin or fat body pictures. After adapting to a thin body, HP judged a thinner than actual body picture to be the most realistic and vice versa, resembling a typical aftereffect. ED only showed such an adaptation effect when they adapted to fat body pictures. The reported results indicate a relationship between body image distortion in ED and visual body image adaptation. It can be suspected that due to a pre-existing, long-lasting adaptation to thin body shapes in ED, an additional visual adaption to thin body shapes cannot be induced. Hence this pre-existing adaptation to thin body shapes could induce perceptual body image distortions in ED.
Expectant care versus surgical treatment for miscarriage.

BACKGROUND Miscarriage is a common complication of early pregnancy that can have both medical and psychological consequences like depression and anxiety. The need for routine surgical evacuation with miscarriage has been questioned because of potential complications such as cervical trauma, uterine perforation, hemorrhage, or infection. OBJECTIVES To compare the safety and effectiveness of expectant management versus surgical treatment for early pregnancy loss. SEARCH STRATEGY We searched the Cochrane Pregnancy and Childbirth Group Trials Register (December 2005), the Cochrane Central Register of Controlled Trials (The Cochrane Library 2004, Issue 3), PubMed (1966 to March 2005), POPLINE (inception to March 2005), and LILACS (1982 to March 2005) and reference lists of reviews. SELECTION CRITERIA Randomized trials comparing expectant care and surgical treatment (vacuum aspiration or dilation and curettage (D & C)) for miscarriage were eligible for inclusion. DATA COLLECTION AND ANALYSIS Two authors independently assessed trial quality and extracted data. We contacted study authors for additional information. MAIN RESULTS Five trials were included in this review with 689 total participants. The expectant-care group was more likely to have an incomplete miscarriage (RR 5.37; 95% CI 2.57 to 11.22). However, the time frames for declaring the process incomplete varied across the studies. The need for unplanned surgical treatment (such as vacuum aspiration or D&C) was greater for the expectant-care group (RR 4.78; 95% CI 1.99 to 11.48). The expectant-care group had more days of bleeding (WMD 1.59; 95% CI 0.74 to 2.45) and a greater amount of bleeding (WMD 1.00; 95% CI 0.60 to 1.40). Post-procedure diagnosis of infection was lower in the expectant-care group (RR 0.29; 95% CI 0.09 to 0.87). Information on psychological outcomes and pregnancy was too limited to draw conclusions. AUTHORS' CONCLUSIONS Expectant management led to a higher risk of incomplete miscarriage, need for surgical emptying of the uterus, and bleeding. None of these were serious. In contrast, surgical evacuation was associated with a significantly higher risk of infection. Given the lack of clear superiority of either approach, the woman's preference should play a dominant role in decision making. Medical management has added choices for women and their clinicians, but these were not reviewed here.
Integrin-linked kinase plays a key role in coxsackievirus replication.

See related article, pages 354–361 Viral infection may be a major cause of idiopathic dilated cardiomyopathy, but little is known about how viruses enter the cardiac myocyte and damage it. Understanding the pathogenesis of viral myocarditis will lead to new strategies for the treatment and prevention of heart failure. In this issue of Circulation Research , Esfandiareiet al show that the integrin-linked kinase (ILK) plays a key role in the lifecycle of the cardiotropic virus Coxsackievirus.1 More than 100 000 patients in the United States have a nonischemic dilated cardiomyopathy, and this disease accounts for 45% of all heart transplants.2,3 More than 25% of the nonischemic dilated cardiomyopathy cases may be caused by viral infections.4 The virus that most commonly infects the heart is Coxsackievirus, a small RNA virus (picornavirus) spread through the fecal–oral route.5 Coxsackievirus infection causes a viral prodrome of fever and myalgias, followed by diarrhea. Approximately 2 weeks after the onset of infection, direct viral injury of cardiac myocytes in combination …
THE DETECTION AND STATISTICS OF GIANT ARCS BEHIND CLASH CLUSTERS

We developed an algorithm to find and characterize gravitationally lensed galaxies (arcs) to perform a comparison of the observed and simulated arc abundance. Observations are from the Cluster Lensing And Supernova survey with Hubble (CLASH). Simulated CLASH images are created using the MOKA package and also clusters selected from the high-resolution, hydrodynamical simulations, MUSIC, over the same mass and redshift range as the CLASH sample. The algorithm's arc elongation accuracy, completeness, and false positive rate are determined and used to compute an estimate of the true arc abundance. We derive a lensing efficiency of 4 ± 1 arcs (with length ≥6″ and length-to-width ratio ≥7) per cluster for the X-ray-selected CLASH sample, 4 ± 1 arcs per cluster for the MOKA-simulated sample, and 3 ± 1 arcs per cluster for the MUSIC-simulated sample. The observed and simulated arc statistics are in full agreement. We measure the photometric redshifts of all detected arcs and find a median redshift zs = 1.9 with 33% of the detected arcs having zs > 3. We find that the arc abundance does not depend strongly on the source redshift distribution but is sensitive to the mass distribution of the dark matter halos (e.g., the c–M relation). Our results show that consistency between the observed and simulated distributions of lensed arc sizes and axial ratios can be achieved by using cluster-lensing simulations that are carefully matched to the selection criteria used in the observations.
Oxidative stability of chilled broiler breast meat as affected by dietary supplementation with rosemary (Rosmarinus officinalis L.) powder and vitamin E

Abstract The aim of the present study was to evaluate the effect of rosemary (Rosmarinus officinalis L.) powder and vitamin E, as feed additives combined at different levels, on oxidative stability of broiler meat up to 14th day after chilling. A total of 270 1‐day‐old male chicks of Ross 308 strain were randomly assigned to nine dietary groups with three replicates having 10 birds each. Diets were supplemented with 0, 0.5, or 1.0% of rosemary (R) powder and 0, 100, or 200 mg/kg of vitamin E (alpha‐tocopherol acetate; VitE) according to the following treatments: T1 – control basal diet (0R + 0VitE); T2 – 0R + 100VitE; T3 – 0R + 200VitE; T4 – 0.5R + 0VitE; T5 – 0.5R + 100VitE; T6 – 0.5R + 200VitE; T7 – 1.0R + 0VitE; T8 – 1.0R + 100VitE; and T9 – 1.0R + 200VitE. At day 42, two birds of each replicate were slaughtered and the length and weight of cecum was recorded. Carcasses and their economically valuable parts were also weighted and broiler breast refrigerated at 4°C for 14 days. At day 0, 4, 7, and 14 of storage the malondialdehyde (MDA) content of breast meat was evaluated. After 4 days of storage, meat MDA contents of the T5 (0.43 mg/kg) and T9 (0.41 mg/kg) were lower than control group (T1: 0.55 mg/kg; p < .05). On day 7, groups supplemented with rosemary or VitE alone showed similar MDA contents (p > .05) than control. On day 14, lower (p < .05) MDA contents than T1 were observed in all groups except for broilers fed diet supplemented only with vitamin E. No effects were observed between treatments on the relative weight of the several carcass traits, however, VitE influenced (p < .05) the weight and size of cecum. Based on our findings, the combination of rosemary powder and vitamin E at different levels in diet is useful to limit the lipid oxidation of chilled chicken meat.
Psychotropic Medication Use in Children and Adolescents with Mental Retardation (MR)

Background: The aim of this study was to assess the medication use in children and adolescents with mental retardation (MR) retrospectively in a cross-sectional study. Method: Between June and December 2013, records of the children and adolescents admitted by our policlinic were retrospectively evaluated and those who had MR diagnosis were analyzed. Results: Male sex was found as statistically related to the presence of psychiatric comorbidity and the pervasive developmental disorders (PDD). At least one medical diagnosis accompanying with MR was found in 49.7% (n=781) of all patients. 79.6% (n=1252) of all patients did not use any medication, 16.7% (n=262) of all sample were using one medication agent, 3.5% (n=55) of patients were using combined pharmacotherapy. The predictors of psychotropic medication were the following: the presence of comorbid any of psychiatric disorders, having attention deficit hyperactivity disorder (ADHD), having conduct disorders (CD) and having anxiety disorders. Conclusions and Recommendations: This study has a descriptive nature of the children with MR admitted to the child psychiatry department. It was noticed that psychotropic agent use is preferable if there is a comorbid situation in mental retardation. There is a need for further studies with prospectively planned, multi-central with larger sampling in our country to draw up a way of health policies related to the children with MR.
PKU_ICL at SemEval-2017 Task 10: Keyphrase Extraction with Model Ensemble and External Knowledge

This paper presents a system that participated in SemEval 2017 Task 10 (subtask A and subtask B): Extracting Keyphrases and Relations from Scientific Publications (Augenstein et al., 2017). Our proposed approach utilizes external knowledge to enrich feature representation of candidate keyphrase, including Wikipedia, IEEE taxonomy and pre-trained word embeddings etc. Ensemble of unsupervised models, random forest and linear models are used for candidate keyphrase ranking and keyphrase type classification. Our system achieves the 3rd place in subtask A and 4th place in subtask B.
Pharmacokinetics and disposition of rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, in rat

1. The pharmacokinetics and disposition of rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, were investigated following single administration of 14 C-rosuvastatin in the Sprague-Dawley rat. 2. Following oral administration of 14 C-rosuvastatin at 1, 5 and 25 mg kg -1, the C max and AUC of the radioactivity in the plasma increased more than the increase in dose ratio. 3. Excretion of radioactivity was 98.0% of the dose in the faeces and 0.4% in the urine up to 168 h after oral administration in the intact rat, and was 55.1% in the bile and 0.5% in the urine up to 48 h post-dosing in the bile duct-cannulated rat. The unchanged compound mainly accounted for the radioactivity in the bile and faeces. 4. In the tissue distribution study, the concentration of the radioactivity in the liver was markedly higher than those in the other tissues, and the radioactivity concentration ratios of the liver to the plasma were between 8 and 25 up to 48 h after oral administration. The liver-specific distribution of rosuvastatin was similarly recognized in whole-body autoradiography. 5. Metabolic profiling studies indicated that rosuvastatin would not be metabolized by CYP enzymes. 6. These results clarified that rosuvastatin selectively distributed in the liver - the target organ - and was excreted in the bile mainly as the unchanged compound.
Regards croisés sur les systèmes de santé américain et français

Vue de l’hexagone, l’organisation américaine du système de santé paraît souvent très éloignée du schéma égalitaire et protecteur qui fait de l’assurance maladie française l’un des piliers du contrat social. Vue de l’autre rive de l’Atlantique, notre assurance maladie est largement incomprise, elle y est perçue par beaucoup comme une ingérence intolérable dans la vie privée des individus. D’où l’image aux États-Unis d’un système de santé français, très collectif et public, et en France d’un système de santé américain fondamentalement individualiste et privatisé. Pourtant leur comparaison ne manque pas de surprendre. Le système de santé français paraît plus proche de celui des États-Unis que de ceux de ses voisins suédois ou anglais. Ce mouvement apparent de convergence ne doit pourtant pas être surestimé [1].
Meeting the Health Care Needs of Female Crack Users: A Canadian Example

ABSTRACT Canada is an egalitarian society committed to accessible and comprehensive health care. Although there has been a tendency to assume that its various social welfare programs have improved health conditions for lower income citizens, Canada's record in ensuring health equality remains poorer than expected (Humphries and van Doorslaer, 2000; Wasylenki, 2001). The Canadian Health Act stipulates that all residents of Canada are to have access to medically necessary hospital and physician services based on need and not the ability to pay. However, for marginalized groups such as drug users and the homeless, structural barriers to better health remain. This paper examines the health care needs and experiences of 30 women who were heavily involved in the street life of crack and prostitution in Toronto. Through their ready access to local drop-in clinics and nearby hospitals, the women reported generally positive experiences with the health care system. The study concludes that the women experienced many of the health problems that typify homeless, poorly housed and economically marginalized groups. Both positive and negative experiences with the health care system, and structural barriers that hamper its full utilization, are identified.
The Effects of Frame of Reference on Responses to Questions About Sexual Assault Victimization and Perpetration1

Self-reports of sexual assault are affected by a variety of factors including the number of questions, question phrasing, and context. Participants (307 women, 166 men) were randomly assigned to one of two forms of a questionnaire. One form had the tactics used to obtain forced sex as the initial frame of reference, whereas the other form had the type of sex that was forced as the initial frame of reference. Seventy-five percent of the women who received the tactics-first version reported that they had at least one victimization experience since the age of 14, as compared to 62% of the women who received the type-of-sex-first version. Sixty-nine percent of the men who received the tactics-first version reported that they had at least one perpetration experience since the age of 14, as compared to 36% of the men who received the type-of-sex-first version. These findings have implications for how questionnaires should be designed to maximize reporting of sexual assault incidents.
Coping motives as a moderator of daily mood-drinking covariation.

OBJECTIVE The current study examines the extent to which college students' reports of drinking to cope (DTC) with negative affect moderate the daily covariation between specific types of negative mood (sadness, fear, hostility, shyness and boredom) and alcohol use. METHOD Participants were full-time college students, aged 18-20, attending a large Southeastern university (N = 72; 50% male). These individuals completed an experience-sampling protocol over a 1-month interval, to assess daily mood and alcohol use. RESULTS A series of Hierarchical General Linear Models found that individuals who reported low motives to cope through drinking showed an expected absence of daily mood and drinking covariation. For those reporting high coping motives, a complex and somewhat counterintuitive series of findings were found; students high in DTC drank less on days in which they experienced greater sadness. Analyses on the quadratic effects of mood revealed that when experiencing moderate to high levels of fear and shyness, individuals high in DTC were more likely to drink. For those low in coping motivations, fear and shyness did not predict daily drinking. CONCLUSIONS Findings highlight the need to better our understanding of the exact meaning of DTC measures. In addition, there is a need to study how the context of college drinking influences self-medication and students' self-reports of DTC.
The Question of 'Stress' in West Greenlandic: An Acoustic Investigation of Rhythmicization, Intonation, and Syllable Weight

The main purpose is to investigate whether stress is a relevant category in Greenlandic word prosody. I focus on tonal and durational parameters. The data material consists of word lists read aloud seven times by two subjects. The main findings are: (1) The prosodic characteristics of words can be explained in either tonal or durational terms. (2) The four different syllable types (of different 'weight') are distinguished in durational terms; further, there appears to be only a tripartite system of short, long and overlong. (3) There are intra-syllabic as well as inter-syllabic rhythmical adjustments. It is concluded that Greenlandic prosody does not include an autonomous stress category, either tonal or durational parameters alone will do. And although Greenlandic has distinctive quantity, there is room for considerable durational variation of segments.
Evaluation of the Outcomes of a Multi-Professional Education Programme in Health Informatics

A multi-professional continuing education programme on healthcare information systems was designed on the basis of the IMIA WG 1 recommendations for teaching health informatics. This paper presents the outcomes of the education programme on the basis of the participants' (n=19) narrative assessments and a questionnaire. According to the results, the participants were very satisfied with their personal learning outcomes and they felt that the programme content was useful for their duties at work. They regarded that particularly the multi-professional group had given them many ideas and rewarding discussions. The learning arrangements were assessed very successful and the learning methods rewarding. In conclusion we suggest that it is important to include different professions--healthcare and technical--into the same continuing education programmes in health informatics, and to include real life-like team projects. The validity of the results to undergraduate education programmes should be studied.
Involvement of Mash1 in EGF-mediated regulation of differentiation in the vertebrate retina.

It is believed that signaling through the epidermal growth factor (EGF) receptor plays a critical role in the development of Drosophila eyes. In the present study we have analyzed the role that EGF-mediated signaling plays in vertebrate retinal development. We have observed that during late retinal neurogenesis EGF delays rod photoreceptor differentiation and that this effect of EGF involves the modulation of expression of a homologue of Drosophila proneural genes, Mash1. EGF causes a significant decrease in Mash1 expression and an increase in the proportion of proliferating cells in the retina in vitro. The decrease in Mash1 expression is accompanied by a concomitant decrease in opsin expression, a marker for overt rod photoreceptor differentiation. Withdrawal of EGF leads to an increase in both Mash1 and opsin expression; however, the onset of expression of Mash1 precedes that of opsin. Our study identifies a proliferative intermediate precursor, characterized by Mash1 expression, that is the target of EGF-mediated suppression of rod photoreceptor differentiation. Based on the evolutionarily conserved roles of EGF- and Notch-mediated signaling in the delay of differentiation in proliferating precursors we propose that these distinct signaling mechanisms act in concert to ensure the fidelity of the strict temporal and spatial nature of cell fate determination in the retina.