Miracle-dz/UniFAR-FTUs huggingface dataset:
Hemangiopericytoma of Greater Omentum Presenting as a Huge Abdominal Lump

Hemangiopericytoma is a rare neoplasm that can occur in any part of the human body, but it rarely develops in the greater omentum. We report a case of a patient who presented with a huge abdominal lump. At laparotomy, a huge vascular tumor, which was observed originating from the greater omentum, was resected. Histopathology investigation revealed this tumor as a benign hemangiopericytoma with a malignant potential.
Nucleotide sequence of the coat protein gene of canine parvovirus

The nucleotide sequence of the canine parvovirus (CPV2) from map units 33 to 95 has been determined. This includes the entire coat protein gene and noncoding sequences at the 3' end of the gene, exclusive of the terminal inverted repeat. The predicted capsid protein structures are discussed and compared with those of the rodent parvoviruses H-1 and MVM.
Physiological Effects of Mining Contaminants on Algae with Special Reference to Heavy Metal Toxicity

The process of mining affects all the components of environment and ecology. resulting in different types of pollution problems like soil, surface and ground water pollution. Acid Mine Drainage (AMD) and mine spoil dumps may contain an elevated amount of Heavy metals. Physiological effect of heavy metal toxicity on algal species like Chlorella vulgaris, Scenedesmusbijugatus, Oscillatoriaamphibia and Lyngbyamajuscula isolated from mine waters of Mansar, Kandri,Beldongari and Gumgaon Manganese mines of MOIL, Nagpur Region were investigated. Results obtained showed significant concentrations of heavy metals in mine spoil and mine water. Observed Mn and Fe concentrations were very high (215.2 to 224.3 and 47.9 to 52.5 mg kg−1, respectively in mine spoil followed by Cu, Zn, Cr, Pb and Cd concentrations. Similarly, mine waters of all sampling sites showed elevated concentrations of manganese (1.645 to 1.745 mg/l), iron (0.950 to 1.124 mg/l) followed by copper (0.029 to 0.032 mg/l) and zinc (0.011 to 0.013 mg/l) while concentrations of cadmium, chromium and lead remained below detecting limit and hence they were selected for toxicity tests. Most of the tested algal species were reported with maximum inhibitory level and TIC to iron and manganese than zinc and copper. Among all algal species cyanophycean member Oscillatoriaamphibia was reported with maximum inhibitory concentration for Mn( 2.5 mg/l), Fe (2.4 mg/l), Cu (1.0 mg/l) and Zn (1.7 mg/l) and Lyngbyamajuscula with Mn ( 2.2 mg/l), Fe (2.3 mg/l), Cu (0.9 mg/l) and Zn (1.4 mg/l) whereas chlorophycean member Chlorella vulgaris was reported with minimum inhibitory concentrations. Tolerance Index Concentration values also revealed more tolerance to iron and manganese and least to copper and zinc. Among cyanophycean members, Oscillatoriaamphibia was reported with more TIC to zinc (0.784 mg/l) while Lyngbyamajuscula with more TIC to iron (1.811 mg/l) followed by manganese (1.574mg/l) and copper (0.665 mg/l). The chlorophycean member, Scenedesmusbijugatuswas reported with more TIC to iron (1.543 mg/l) followed by manganese (1.268 mg/l) and copper (0.227 mg/l) whereas Chlorella vulgaris with more TIC to zinc (0.271 mg/l). Overall, all the algal species were affected by heavy metal toxicity and their observed tolerance to the heavy metals especially to higher concentrations of Mn and Fe might be due to adaptation contaminated mine water in the vicinity of mines.
Clinical factors related to the aqueous levels of vascular endothelial growth factor and hepatocyte growth factor in proliferative diabetic retinopathy.

PURPOSE To investigate clinical factors related to the aqueous humor levels of vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) in patients with proliferative diabetic retinopathy (PDR). METHODS Undiluted aqueous humor was obtained during ocular surgery from 46 eyes of 46 patients and the levels of growth factors were measured using enzyme-linked immunosorbent assays. VEGF and HGF levels were compared with the number of photocoagulation. VEGF and HGF levels in patient groups stratified according to the existence of vitreous hemorrhage, retinal detachment, and fibrovascular membrane were analyzed. And clinical parameters associated with the growth factors were determined by multiple regression analysis. RESULTS The levels of VEGF decreased significantly as the extent of photocoagulation increased and showed significant positive correlation with the existence of vitreous hemorrhage. There was no significant correlation between VEGF levels and the existence of fibrovascular membrane and traction retinal detachment. The levels of HGF also decreased significantly as the extent of photocoagulation increased, but increased significantly when fibrovascular membrane existed. There were no significant correlations between HGF levels and the existence of vitreous hemorrhage and traction retinal detachment. Concerning systemic conditions, each growth factor has no significant correlation with duration and type of diabetes mellitus, the treatment regimen, the control of hemoglobin A1C, and the existence of hypertension or renal dysfunction. CONCLUSION The therapeutic effect of panretinal photocoagulation on PDR might be partly exerted by reduction of the levels of VEGF and HGF in ocular fluid. Since the clinical parameters associated with VEGF were different from those associated with HGF, these growth factors might influence the progression of retinopathy in different ways.
Sickness absence with low-back, shoulder, or neck diagnoses: an 11-year follow-up regarding gender differences in sickness absence and disability pension.

BACKGROUND There is very little knowledge on the long-term outcomes of sickness absence. The aim was to investigate sickness absence and disability pensions over 11 years in a cohort of young persons initially long-term sick listed with back, neck, or shoulder diagnoses. METHOD A prospective population-based cohort study of all 213 individuals in the Municipality of Linköping, Sweden, who in 1985 were aged 25-34 and had at least one new sick-leave spell > 28 days with such diagnoses. MAIN RESULTS More women (61%) than men fulfilled the inclusion criteria. In 1996, 22% of the cohort (14% of the men, 26% of the women) had been granted disability pension; 76% of these individuals with musculoskeletal and the rest with psychiatric diagnoses. Partial disability pension was granted to 59% of the women, 17% of the men. Women were more often granted temporary disability pension than men. CONCLUSIONS This proved to be a high-risk group for disability pension. There were large and somewhat unexpected gender differences regarding incidence and type of disability pension. It has been debated how soon physicians should be concerned about the risk of long-term disability regarding these diagnoses; at four or eight weeks of sickness absence - our results support the former, at least for women.
Survival of Escherichia coli in Freshwater

Experiments on the survival of Escherichia coli were conducted in the water of man-made Zegrzynski Reservoir. The aim of this study was to evaluate how selected biocenotic factors (predation, coliphage infection, presence of autochthonic microflora and nutrient conditions) affect this process. We observed residual living cells of E. coli up to about thirty days of the investigation. We found that the major factor that was responsible for mortality of E. coli was microflagellate grazing and exposure to an aquatic environment. Size-selective preferences of microflagellates toward E. coli cells were observed. No visible effect of bacteriophages on the survival of E. coli was detected. Better nutritional condition and the presence of native heterotrophic microflora significantly prolonged the survival time of E. coli in the studied environment.
Probe compensated NF-FF transformation with planar wide-mesh scanning

The Near-Field - Far-Field (NF-FF) transformation technique with plane-rectangular scanning is undoubtedly the most simple and efficient one from the analytical and computational viewpoints. However, the antenna far field can be reconstructed only in a cone with an apex angle less than 180° unless repeating the measurements. Accordingly, such a scanning is particularly suitable for highly directive antennas radiating pencil beam patterns.
Joint Representation of Depth from Motion Parallax and Binocular Disparity Cues in Macaque Area MT

Perception of depth is based on a variety of cues, with binocular disparity and motion parallax generally providing more precise depth information than pictorial cues. Much is known about how neurons in visual cortex represent depth from binocular disparity or motion parallax, but little is known about the joint neural representation of these depth cues. We recently described neurons in the middle temporal (MT) area that signal depth sign (near vs far) from motion parallax; here, we examine whether and how these neurons also signal depth from binocular disparity. We find that most MT neurons in rhesus monkeys (Macaca Mulatta) are selective for depth sign based on both disparity and motion parallax cues. However, the depth-sign preferences (near or far) are not always aligned: 56% of MT neurons have matched depth-sign preferences (“congruent” cells) whereas the remaining 44% of neurons prefer near depth from motion parallax and far depth from disparity, or vice versa (“opposite” cells). For congruent cells, depth-sign selectivity increases when disparity cues are added to motion parallax, but this enhancement does not occur for opposite cells. This suggests that congruent cells might contribute to perceptual integration of depth cues. We also found that neurons are clustered in MT according to their depth tuning based on motion parallax, similar to the known clustering of MT neurons for binocular disparity. Together, these findings suggest that area MT is involved in constructing a representation of 3D scene structure that takes advantage of multiple depth cues available to mobile observers.
Effects of Group Music Intervention on Behavioral and Psychological Symptoms in Patients with Dementia: A Pilot-Controlled Trial

We investigated the effects of group music intervention on behavioral and psychological symptoms in patients with dementia. Twenty patients were nonrandomly allocated to either a music-intervention group, or an usual care group. The music-intervention group received 50 minutes of music intervention 3 times per week for 5 consecutive weeks. After 15 sessions, the music-intervention group showed significant in improvement with regard to agitation, and the total scores of both patients and caregivers were lower, compared with the control group. These findings suggest that music can improve behavioral and psychological symptoms, especially in patients with dementia and their caregivers.
Effect of Nintedanib in Subgroups of Idiopathic Pulmonary Fibrosis by Diagnostic Criteria

Rationale: In the absence of a surgical lung biopsy, patients diagnosed with idiopathic pulmonary fibrosis (IPF) in clinical practice could participate in the INPULSIS trials of nintedanib if they had honeycombing and/or traction bronchiectasis plus reticulation, without atypical features of usual interstitial pneumonia (UIP), on high‐resolution computed tomography (HRCT). Thus, the patients in these trials represented patients with definite UIP and a large subgroup of patients with possible UIP. Objectives: To investigate the potential impact of diagnostic subgroups on the progression of IPF and the effect of nintedanib. Methods: We conducted a post hoc subgroup analysis of patients with honeycombing on HRCT and/or confirmation of UIP by biopsy versus patients without either, using pooled data from the INPULSIS trials. Measurements and Main Results: Seven hundred twenty‐three (68.1%) patients had honeycombing and/or biopsy, and 338 (31.9%) patients had no honeycombing or biopsy. In these subgroups, respectively, the adjusted annual rate of decline in FVC in patients treated with placebo was −225.7 and −221.0 ml/yr, and the nintedanib versus placebo difference in the adjusted annual rate of decline in FVC was 117.0 ml/yr (95% confidence interval, 76.3‐157.8) and 98.9 ml/yr (95% confidence interval, 36.4‐161.5). There was no significant treatment‐by‐subgroup interaction (P = 0.8139). Adverse events were similar between the subgroups. Conclusions: Patients with IPF diagnosed in clinical practice who had possible UIP with traction bronchiectasis on HRCT and had not undergone surgical lung biopsy had disease that progressed in a similar way, and responded similarly to nintedanib, to that of patients with honeycombing on HRCT and/or confirmation of UIP by biopsy.
Managing Creativity in Small Worlds

Greater job mobility among engineers and scientists has caused the extended social networks of inventors to become increasingly connected. As a result, invention increasingly occurs within small worlds (or social networks) that straddle firm boundaries. Small worlds provide both strategic opportunity and potential threat; while they can increase creativity within a firm, they also aid in the diffusion of creative knowledge to other firms through personnel and knowledge transfer. Firms that operate within small worlds such as in Silicon Valley long agolearned to manage invention in an environment of rampant knowledge spillovers across firm boundaries. Now, however, all firms need to learn how to manage innovation in a small world environment. This article offers them advice about how to do this. (Publisher’s Abstract)
AVALIAÇÃO HIGIÊNICO-SANITÁRIA DE CARNE MOÍDA COMERCIALIZADA EM AÇOUGUES DA CIDADE DE SARANDI, PR, BRASIL

O consumo de carne bovina pela população brasileira tem aumentado nos últimos anos. No entanto, o processamento deste produto pode favorecer a sua contaminação por microrganismos e desencadear surtos de infecção alimentar. Baseado nestas informações, o objetivo do presente trabalho foi avaliar a qualidade higiênico-sanitária da carne moída comercializada em 20 açougues da cidade de Sarandi, PR. Foram coletadas amostras de 50 gramas do produto em cada estabelecimento. Em seguida foi verificada a presença de coliformes totais e termotolerantes pela Técnica do Número Mais Provável e de Salmonella spp. por crescimento em meio específico. Foi observada a presença de coliformes termotolerantes em todas as amostras analisadas; porém, em nenhuma delas houve o crescimento de Salmonella spp. A presença de Escherichia coli no alimento indica falha nos procedimentos higiênico-sanitários, ressaltando a importância de implementar medidas que promovam melhoria nas boas práticas de higiene, a fim de reduzir os índices de contaminação destes produtos e aumentar a qualidade de vida do consumidor.
Lactate elimination and glycogen resynthesis after intense bicycling

Objective. Muscles break down glycogen to lactate during intense exercise, and in the recovery period, glycogen reappears while lactate disappears. The purpose of this study was to examine to what extent lactate is resynthesized to glycogen within the formerly active muscles themselves in man. Material and methods. Fifteen healthy young men cycled for 2 min to exhaustion. Muscle biopsies were taken from the knee extensor muscle before the exercise, just after the ride, and again after 45 min of recovery. In addition, blood samples were taken from the femoral artery and vein, and the leg blood flow was measured using the ultrasound Doppler technique. The muscle biopsies were analysed for glycogen, lactate and other metabolites, and the blood samples were analysed for lactate and glucose. The exchanges of lactate and glucose of the leg were assessed by multiplying the measured arterio–venous (a–v) differences by the blood flow. Results. During the exercise the muscles broke down 20±4 mmol glycogen kg−1 wet muscle mass and produced 26±1 mmol lactate kg−1. In the recovery period after 24±1 mmol lactate kg−1 had disappeared, of which 48 % was released to the blood, 52 % disappeared within the muscle. An R‐value of 0.62 across the leg suggests that none of the lactate was oxidized. Altogether, 10±3 mmol glycogen kg−1 reappeared during recovery. Glucose uptake accounted for 2 mmol kg−1 and glycolytic intermediates (G‐6‐P and free glucose) accounted for 4 mmol kg−1; 4 mmol glycogen kg−1 (42 %) reappeared from unknown sources. Conclusions. The present data are compatible with the idea that around half of the lactate produced during intense bicycling is resynthesized to glycogen within the working muscles themselves in the recovery period after the bicycling.
Temporary Threshold Shift after Exposure to Noise and Music of Equal Energy

Ten voluntary subjects were exposed to 10 min of recorded pop music on five occasions. On five other occasions these subjects were exposed to a noise with level-, frequency-, and time-distribution characteristics, measured in octave-band steps, equal to those of the music. Measurements of temporary threshold shift showed almost equal sensitivity to the two stimuli in four subjects, whereas six others demonstrated marked differences in sensitivity. Differences were always due to more temporary threshold shift after exposure to the nonmusical noise stimulus. These findings imply that factors other than physical properties of the fatiguing sound contribute to the degree of temporary threshold shift.
Induction of micronuclei and superoxide production in neuroblastoma and glioma cell lines exposed to weak 50 Hz magnetic fields

Extremely low-frequency (ELF) magnetic fields (MF) have been associated with adverse health effects in epidemiological studies. However, there is no known mechanism for biological effects of weak environmental MFs. Previous studies indicate MF effects on DNA integrity and reactive oxygen species, but such evidence is limited to MFs higher (greater than or equal to 100 µT) than those generally found in the environment. Effects of 10 and 30 µT fields were studied in SH-SY5Y and C6 cells exposed to 50-Hz MFs for 24 h. Based on earlier findings, menadione (MQ) was used as a cofactor. Responses to MF were observed in both cell lines, but the effects differed between the cell lines. Micronuclei were significantly increased in SH-SY5Y cells at 30 µT. This effect was largest at the highest MQ dose used. Increased cytosolic and mitochondrial superoxide levels were observed in C6 cells. The effects on superoxide levels were independent of MQ, enabling further mechanistic studies without co-exposure to MQ. The micronucleus and mitochondrial superoxide data were consistent with a conventional rising exposure–response relationship. For cytosolic superoxide, the effect size was unexpectedly large at 10 µT. The results indicate that the threshold for biological effects of ELF MFs is 10 µT or less.
Inflammation and metabolism in tissue repair and regeneration

Tissue repair after injury is a complex, metabolically demanding process. Depending on the tissue’s regenerative capacity and the quality of the inflammatory response, the outcome is generally imperfect, with some degree of fibrosis, which is defined by aberrant accumulation of collagenous connective tissue. Inflammatory cells multitask at the wound site by facilitating wound debridement and producing chemokines, metabolites, and growth factors. If this well-orchestrated response becomes dysregulated, the wound can become chronic or progressively fibrotic, with both outcomes impairing tissue function, which can ultimately lead to organ failure and death. Here we review the current understanding of the role of inflammation and cell metabolism in tissue-regenerative responses, highlight emerging concepts that may expand therapeutic perspectives, and briefly discuss where important knowledge gaps remain.
The postnatal growth of the rat lung III. Morphology

In order to investigate the postnatal growth of the gas exchange apparatus, the lungs of rats aged 1, 4, 7, 10, 13, and 21 days were fixed by intra‐tracheal instillation of glutaraldehyde. The analysis and interpretation of the morphological changes observed by light and electron microscopy were based on the results of previous morphometric and autoradiographic studies performed on the same material.
The significance of −786T > C polymorphism of endothelial NO synthase (eNOS) gene in severe preeclampsia

Objective. Preeclampsia (PE) is believed to be induced by endothelial cell dysfunction in placenta. Highly polymorphic endothelial nitric oxide synthase (eNOS) activity belongs to the factors significantly influencing vaso-motor tone in placenta and PE susceptibility. The aim of this study was to evaluate prevalence of −786T/C polymorphism of eNOS gene in the groups of women with mild and severe PE. Study design. The study was performed in the group of 218 preeclamptic (including 136 with severe PE) and of 400 normotensive healthy women delivered normally after a healthy gestation. The eNOS −786T/C polymorphism was determined using PCR/RFLP assay. Additionally, detailed correlation between eNOS genotypes and clinical/laboratory data in the PE group has been analyzed. Results. The higher frequency of mutated homozygous CC genotypes (17.4% vs. 11.5% in controls, OR 1.62, n.s.) and of C alleles (allelic frequency 44.1 vs. 36.6%; OR 1.36, p = 0.012) in the group of PE has been determined. Furthermore, in the group of severe PE the overrepresentation of mutated CC genotypes (23.5% vs. 11.5%, OR 2.37, p = 0.0014) and mutated C alleles (47.8 vs. 36.6%, OR 1.58, p = 0.0016) has been found. Conclusions. The presence of mutated homozygous CC genotype and C allele of −786T/C polymorphism of eNOS gene influences the higher susceptibility to develop severe PE development.
Spatial and vertical biogeography of coral reef sediment bacterial and diazotroph communities

Coral reefs are globally important marine ecosystems as sites of high biotic diversity. Reef flat sediments are reasonably homogeneous in composition. This substratum is subject to gradi- ents in water motion, grazing pressure and benthic productivity. This study used DNA fingerprinting techniques, automated rRNA intergenic spacer analysis (ARISA), and terminal restriction fragment length polymorphism (TRFLP) to examine patterns of bacterial assemblage composition within Heron Reef flat sediments, targeting the entire bacterial community (not including Archaea) and nitrogen- fixing bacteria. ARISA fingerprints contained between 51 and 148 operational taxonomic units (OTU) per surface sediment sample. The mean whole-community similarity between adjacent sites along a transect from Heron Island to the reef crest was 0.50 ± 0.03 (mean ± SE) Whittaker Index (comparison of relative abundances) and 0.46 ± 0.03 Jaccard Index (presence/absence only). Comparison of sedi- ment community fingerprints to a water column community fingerprint collected above the reef flat at high tide indicated that sediments contained different assemblages to the water column (mean similarity between sediments and water column assemblage = 0.15 ± 0.01 Jaccard Index); however, assemblage composition did not differ significantly from that expected by random association. Verti- cal sediment cores showed dissimilarity between surface (0 to 3 cm) and deep (3 to 5 cm) community fingerprints, which was probably related to redox state. Comparison of fingerprints of fecally-derived sediments from the sea cucumber Holothuria atra and surrounding sediments indicated that the impact of metazoan grazing could not be distinguished from ambient small spatial scale variability in sediment assemblage composition. The nifH-TRFLP fingerprints of sediment prokaryotic assem- blages (amplified from all samples, but only in sufficient quantities for analysis from 7 locations) indi- cated the presence of ubiquitous, potentially diverse diazotroph communities, with little assemblage similarity between locations. Our results suggested that while bacterial assemblages (including communities of nitrogen-fixing bacteria) in sediments of a coral reef are diverse, their assemblage composition is not related to grazing pressure but may be influenced by other biotic and abiotic environmental conditions such wave energy and sediment depth.