Miracle-dz/UniFAR-FTUs huggingface dataset:
Stress Reactions Resulting from the Relocation of an aged Population *

Fifty-four subjects from 64 to 94 years of age were investigated for their stress reactions following their relocation from one site to another. Forty of them, 16 men and 24 women, were psychiatrically normal, while the remainder (eight men and six women) were suffering from a psychosis, which in all cases, except one, was of organic type. There was no statistically significant difference between the ages of the men and women, and of the normals and psychotics. The same was true in the case of the body weight, except that the men weighed more than the women. Plasma corticoid (PC) levels were determined two to nine days before relocation and eight to 17 days afterwards. One-third of the subjects made no complaints in regard to their health within four months of relocation (NC 33%), while the rest either reported symptoms for which there did not appear to be any apparent organic cause (WS 43%) or presented organic signs (OS 24%). Most of the complaints in the WS category were related to the abdomen, while most of those in the OS group were either due to respiratory infections or cardiovascular conditions. The relative percentage of persons falling into these three categories was essentially similar in normal men and in normal women and in psychotic men and psychotic women. However, the psychotics had a significantly higher incidence of OS persons and a significantly lower number of NC subjects than did the normals, while the incidence of WS was essentially the same in these two groups. Following relocation the PC levels increased in normal men, but decreased in normal women. Furthermore, a greater PC increase was observed in men of the OS group than in those of the WS category, who in turn showed a greater increase than the NC males. This was not observed in the women. Men in each of the NC, WS and OS categories had higher PC levels than women of the same category, and psychotics higher than normals. Twenty-five per cent of the normal men died within the first six months of relocation but none of the normal women, a statistically significant difference. Within 23 months of relocation reliably more psychotics died than normals. In conclusion, normal aged men appeared to suffer more from the relocation than normal aged women, and psychotic aged persons more than psychiatrically normal subjects of the same age.
Building Sustainable Organizational Social Capital: The Global Leadership Challenge

Building social capital (SC) is increasingly recognized as essential for organizational and social growth. However, there is a scant amount of literature on how leaders are expected to develop SC as an individual and organizational competence. While this article develops new frameworks for both SC and global leadership (GL), it offers practical suggestions to practitioners in human resource development and management on how they can set up strategies for developing both GL and SC.
The Internationalization And Hr Strategies Of Emerging Market Multinational Enterprises (Em Mnes): The Case Of Thai Em Mnes

This paper uses a matched case comparison of two Thai multinational enterprises (MNEs) in the food industry, Charoen Pokphand (CP) and Thai Union Frozen Products (TUF), to examine how emerging market MNEs (EM MNEs) successfully overcome the liability of foreignness and the liability of origin. I also examine whether different business strategies and internationalization strategies are associated with different HR strategies for managers and professional employees in EM MNEs. CP, the world’s largest producer of animal feed and shrimp among other products, is a paternalistic corporation that has focused on an exploitation business strategy; it has grown organically in the international arena from a family-owned business. It has remained almost completely vertically integrated across its supply chain. By contrast, TUF, the world’s largest canned tuna producer, has focused on an exploration business strategy, has expanded globally through M&A, and has outsourced parts of its supply chain. Its HR strategies for managers and professional employees diverge as a result. CP mainly relies on internal labor market or “making” HR strategies to build a set of loyal Thai and local managers and professional employees who run their operations at headquarters and in other developing countries (south-south expansion) to overcome the two types of liabilities. By contrast, TUF, relies on external labor market or “buying” managers and professional employees from other well-recognized companies when it enters developed countries (south-north expansion) to overcome the two types of liabilities, to learn from developed country practices, and to help integrate the headquarters with the brands and / or subsidiaries.
Corporate Environmental Accounting

The Framework of Environmental Accounting Introduction to Environmentally Differentiated Accounting Environmentally Differentiated Managerial Accounting Environmentally Differentiated Financial Accounting Other Environmentally Differentiated Accounting Systems Management Introduction to Ecological Accounting Internal Ecological Accounting External Ecological Accounting Other Accounting Systems Integrating Traditional and Ecological Accounting Environmental Reporting Environmental Accounting Serving Environmental Outlook.
Limited benefit of pentostatin salvage therapy for steroid‐refractory grade III‐IV acute graft‐versus‐host disease

Corticosteroid‐refractory (SR) acute graft‐versus‐host disease (aGVHD) remains a major cause of morbidity and mortality after allogeneic hematopoietic cell transplantation. Multiple agents have been evaluated in this setting, but the benefit of pentostatin has not been described well. We report a single‐center experience of pentostatin salvage therapy for SR aGVHD. Fifteen patients received pentostatin for SR aGVHD from March 2005 till March 2010 after failure to respond to methylprednisolone ≥2 mg/kg/d for at least seven d. All patients had grade III‐IV aGVHD prior to pentostatin therapy. Thirteen (87%), 10 (67%), and six (40%) patients had gastrointestinal (GI), skin, and liver involvement of aGVHD, respectively. Pentostatin was given at a median of 33 d after steroid therapy initiation. The dose of pentostatin was 1.4 mg/m2 daily for three d, repeated every two wk. Eight (53%) patients also received additional therapies. Complete responses were noted in two patients (both in skin). However, one patient relapsed and did not respond to additional salvage treatment. Partial responses were seen in three patients. Fourteen died of GVHD‐related causes. This study suggested that pentostatin is of limited benefit in the treatment for SR grade III‐IV aGVHD.
Significant effects of implementation of health-promoting schools on schoolteachers’ nutrition knowledge and dietary intake in Taiwan

Abstract Objective Although teachers are the key participants in health-promoting schools (HPS) programme delivery, it is still unknown whether teachers are appropriate health information resources and role models for students with respect to healthy diets. The present study aimed to investigate the effects of implementing HPS programmes on teachers’ nutrition knowledge and diets. Design One HPS programme aiming at dietary intervention (HP-D) and one HPS not aiming at dietary intervention (HP-ND) were selected, along with two non-health-promoting (NHP) schools matched for school size and urbanization level with the two HPS. All 361 teachers in the four schools were invited to participate, yielding a 78·4 % overall valid response rate. A structured, self-reported questionnaire was administered, with regression models used for statistical analysis. Results Teachers in the HP-D group had a mean score of 21·1 on a range of 0–30 for nutrition knowledge, which was significantly higher than the mean scores of 18·5 in the HP-ND group and 19·1 in the NHP group (P < 0·001). Better dietary behaviours were also observed among HP-D teachers. Further, being a ‘health education’ course instructor was associated with significantly higher scores on nutrition knowledge (β = 2·6, P < 0·001) and vegetable and fruit consumption (β = 1·4, P = 0·02) in the HP-D group than in the NHP group. The HP-ND and NHP groups exhibited similar patterns of non-significant differences compared with the HP-D group. Conclusions Implementation of a coordinated HPS framework on nutrition and diet was positively correlated with schoolteachers’ nutrition knowledge and dietary intake.
An Investigation into the Impact of Investor Relations on the Profitability of Director Share Trading

Investor relations are costly activities undertaken by firms to align the expectations of the shareholders with that of the company. These activities involve interactions with investors and analysts as well as voluntary information disclosures intended to reduce information asymmetry while increasing firm visibility (Brennan and Tamarowski, 2000; Bushee and Miller, 2005). Therefore, we expect a firm's investment in investor relations (IR) to also reduce private information held by directors, which results in less profitable share trading. We examine the investor relations policies and director share trading activity of S&P/ASX 300 firms from 2003 to 2004. The results show that with their purchases, directors in high IR firms earn higher returns than those in low IR firms. For sales however, a higher investment in IR lowers the losses avoided by directors. In addition, the price impact of directors' trades does not appear to vary with a firm's IR policy. These findings suggest that because directors trade for information and liquidity reasons, the impact of IR on the profitability of their trades differs between purchases and sales. This in turn can also be interpreted as inconclusive as to whether the practice of IR represents the disclosure of "new" information or simply a repackaging of public information.
Amplitude and phase calibration of hydrophones by heterodyne and time-gated time-delay spectrometry

Two methods for the amplitude and phase calibration of hydrophones based on time-delay spectrometry are presented: a time-gating technique and heterodyne frequency conversion that allows the phase-locked (i.e., coherent) detection of hydrophone signals. Amplitude and phase of the hydrophone sensitivity are obtained in the frequency range 1-20 MHz. In addition, to show the broad-band capabilities of the methods, amplitude values are measured between 4 and 50 MHz.
What determines the use of holding companies and ownership chains

The paper investigates the role of holding companies and conduit entities in German inbound and outbound FDI. It identifies the relevant conduit countries that act as stepping stones. Several tax and non-tax factors for the set-up of indirect structures are empirically identified. Withholding taxes, credit systems in capital exporting countries and the possibility of group consolidation are shown to be empirically important for the design of ownership chains in foreign direct investment.
On Myopic Equilibria in Dynamic Games with Endogenous Discounting

This paper derives an equilibrium for a competitive multi-stage game in which an agents' current action influences his probability of survival into the next round of play. This is directly relevant in banking, where a banks' current lending and pricing decisions determines its future probability of default. In technical terms, our innovation is to consider a multi-stage game with endogenous discounting. An equilibrium for such a multi-stage game with endogenous discounting has not been derived before in the literature.
Split-Off Ipos: Market Returns and Efficiency

This paper investigates split-off initial public offerings (IPOs). Our objective is to investigate the returns prior and subsequent to the offering date of split-off IPOs for hightechnology firms in the most recent bull market. Such an investigation is warranted for at least two reasons. First, if both the parent’s and the subsidiary’s stock price increase significantly prior to the IPO, but the parent’s stock price declines but a greater, share-adjusted, basis than the subsidiary’s stock price increases following the IPO, arbitrage opportunities may result. Second, in light of the large, one-day returns observed during 1999 for high-technology companies, an observation of mispriced technology split-off IPOs may be possible. Using a sample of ten recent split-off IPOs, the market price of parent companies carving out a small percentage of a major subsidiary tends to rise one month prior to the filing date and continues to rise until the offering date. Furthermore, this increase is highly related to the success of the IPO on the first trading day subsequent to the IPO. Furthermore, the market appears to anticipate the extent of the success of the IPO correctly. Subsequent to the offering day, the subsidiaries perform well for about three months, while the parent company performs poorly, on average, giving up nearly all of its pre-offering gains. Further investigation of potential arbitrage opportunities indicates that, if both the parent and the subsidiary can be shorted, very large trading profits can be obtained. This result holds for pairs of stocks where the parent’s price includes at least 20 percent of the subsidiary’s price.
Characteristics and Signi fi cance of Intergenic Polyadenylated RNA Transcription in Arabidopsis 1 [ W ] [ OA ]

The Arabidopsis (Arabidopsis thaliana) genome is the most well-annotated plant genome. However, transcriptome sequencing in Arabidopsis continues to suggest the presence of polyadenylated (polyA) transcripts originating from presumed intergenic regions. It is not clear whether these transcripts represent novel noncoding or protein-coding genes. To understand the nature of intergenic polyA transcription, we first assessed its abundance using multiple messenger RNA sequencing data sets. We found 6,545 intergenic transcribed fragments (ITFs) occupying 3.6% of Arabidopsis intergenic space. In contrast to transcribed fragments that map to protein-coding and RNA genes, most ITFs are significantly shorter, are expressed at significantly lower levels, and tend to be more data set specific. A surprisingly large number of ITFs (32.1%) may be protein coding based on evidence of translation. However, our results indicate that these “translated” ITFs tend to be close to and are likely associated with known genes. To investigate if ITFs are under selection and are functional, we assessed ITF conservation through cross-species as well as within-species comparisons. Our analysis reveals that 237 ITFs, including 49 with translation evidence, are under strong selective constraint and relatively distant from annotated features. These ITFs are likely parts of novel genes. However, the selective pressure imposed on most ITFs is similar to that of randomly selected, untranscribed intergenic sequences. Our findings indicate that despite the prevalence of ITFs, apart from the possibility of genomic contamination, many may be background or noisy transcripts derived from “junk” DNA, whose production may be inherent to the process of transcription and which, on rare occasions, may act as catalysts for the creation of novel genes.
A single center experience with high-dose (HD) IL-2 treatment for patients with advanced melanoma and pilot investigation of a novel gene expression signature as a predictor of response.

9003 Background: HD IL-2 remains one of two FDA-approved therapies for the treatment of patients (pts) with advanced melanoma. Initial studies conducted 15-20 years ago reported 16% response rate with 8% of pts achieving durable responses. The toxicity of HD IL-2 limits its application to pts treated in specialized centers. We present the clinical outcome of pts treated over a recent 2 year period with HD IL-2 at a single institution and an associated retrospective pilot study evaluating the predictive value of a novel tumor gene expression signature. METHODS Clinical and radiological data were collected and analyzed on 49 consecutive pts treated with HD IL-2 at Beth Israel Deaconess Medical Center from 10/05 - 10/07. Response was evaluated via RECIST. Formalin-fixed paraffin embedded tumor was obtained on consenting pts and classified as either Class 1, defined by melanocyte-specific genes including MITF, or Class 2, represented by immune genes, using the DNA-mediated Annealing, Selection, and Ligation (DASL) technique. Two-sided Fisher's Exact test was used to compare the proportion of responses for pts in the two classes. RESULTS Clinical response occurred in 16 of the 49 pts (32.6%), with 5 pts (10.2%) having a CR. Two other pts had stable disease > 12 mos; 3 pts who progressed after response had resection to NED. 10 pts remain disease/progression free at a minimum of 16 mos following treatment. 28 pts (including 13 of 16 responders) had sufficient tumor for DASL analysis. Among the 21 categorized as Class 1, 7 (33%) were responders. Of the 7 classified as Class 2, 6 (86%) were responders. This difference in response was statistically significant (p = 0.0286). CONCLUSIONS The overall and CR rates in a contemporary series of pts with metastatic melanoma treated with HD IL-2 are twice that reported in initial studies suggesting some treatment selection on clinical grounds since the 1990s. Pts with tumors expressing an immune signature by DASL appeared more likely to respond. This finding requires prospective validation, but suggests immune-related gene expression might contribute to IL-2 responsiveness. [Table: see text].
Mutual Fund Herding and Dispersion of Analysts' Earnings Forecasts

We examine the relation between herding of mutual funds and dispersion of analysts' earnings forecasts to ascertain whether it is the lack of information or the arrival of correlated information that induces herding. Results show that the level of herding in individual stocks is positively related to the dispersion measure. Herding is also related to other information quality variables such as stock return volatility and analyst coverage. Our results suggest that fund managers herd in response to lack of reliable information, rather than to exploit correlated fundamental information. Although market capitalization and trading volume are also related to herding, they seem to capture the firm characteristic to which mutual funds are attracted to (or repelled from). Our evidence indicates that buy- and sell-herding respond asymmetrically to information uncertainty. Sell-herding is more prevalent and is positively related to forecast dispersion. Buy-herding, on the other hand, is not related to dispersion. The asymmetric relationship between herding and information uncertainty is consistent with the "prospect theory" and "sharing-of-the-blame" under bad news.
1 The Normal Human Endometrium but not 2 Myometrium Presents Menstrual Cycle-Dependent 3 Fluctuations in the Immunoexpression of DNA 4 Fragmentation Factor 40 , DNA Fragmentation Factor 5 45 , and B-cell Lymphoma 2 Protein . 6

DNA fragmentation factors 40 and 45 (DFF40 and DFF45) and B-cell lymphoma 2 (Bcl-2) 16 expression were evaluated in the normal human endometrium and myometrium. DFF40, DFF45, 17 and Bcl-2 expression was assessed via immunohistochemistry in the proliferative, secretory, and 18 atrophic endometrium and myometrium collected postmenopausally and premenopausally during 19 the proliferative and secretory phases of the menstrual cycle. The endometrium showed 20 significantly higher DFF40 and DFF45 expression than that in the uterine myometrium; compared 21 to the stroma, endometrial glands showed the highest expression in preand postmenopausal 22 specimens. Glandular expression of DFF45 was dependent on the menstrual cycle, reaching its 23 highest level in the secretory endometrium. The glandular expression of DFF40 and DFF45 was 24 significantly lower in postmenopausal specimens than that in premenopausal tissue. No cycle25 dependent changes were reported for stromal or myometrial DFF40 or DFF45 expression. 26 Compared to the endometrial stroma and myometrium, Bcl-2 showed the highest expression in the 27 glandular proliferative endometrium and the lowest expression in the stromal secretory 28 endometrium and myometrium during the secretory phase of the cycle. DFF45 and Bcl-2 showed 29 menstrual cycle-dependent expression, which was limited to the glandular layer of the 30 endometrium. 31
INTRAORBITAL MENINGIOMAS ENCASING THE OPTIC NERVE

According to Reese (1963), meningiomas constitute 17 O / O of all tumours of the central nervous system. They are most often found parasagittally and in the cribriform, tubercular and sphenoidal regions (Bailey, 1948), but may originate anywhere from the dura on the inside of the cranium or from the falx and the tentorium. Of special interest to the ophthalmologist are: suprasellar, presellar, sphenoid ridge and orbital meningiomas. I n a series of 230 consecutive cases of unilateral expanding lesions of the orbit, Reese (1963) found meningiomas in 11 ( 5 ' 0 i o ) . In a series of 31 cases of orbital tumours, Dandy (1941) found one with dural tumours of the orbit without positive roentgenograms of the skull. This case was bilateral, which is exceedingly rare. In the majority of cases orbital meningiomas originate intracranially, primary meningiomas of the orbit being comparatively rare. Craig & Gogela (1949) included as orbital meningiomas even those that arose within the confines of the optic canal and subsequently extended both intraorbitally and intracranially. The purpose of this paper is to report two cases of meningioma originating from the orbital portion of the optic nerve and surrounding it like a cuff.
Quality of Life Determinants in Breast Cancer Patients in Central Rural India

Introduction: Breast cancer is the most frequently diagnosed cancer among women throughout world, with incidence rates increasing in India. Improved survival in breast cancer patients has resulted in their quality of life (QOL) becoming an important issue. Identifying determinants for QOL may provide insights into how to improve their living conditions. This study aimed to assess socio-demographic and clinical factors, as well as the role of self-efficacy, in relation to QOL among women with breast cancer in rural India. Methods: A total of 208 female patients with infiltrating carcinoma of the breast participated in the study. A questionnaire was administered that included sections for socio-demographic characteristics, clinical stage of the cancer and patient delay in seeking health care. A standardized instrument to measure self-efficacy was applied. To assess QOL, the WHOQOL – BREF instrument was used. Results: The overall mean score for QOL was 59.3. For domain 1 (physical health) the mean score across all groups was 55.5, for psychological health 58.2, for social relationships 63.2 and for environmental factors, 60.4. The environmental domain in QOL was negatively associated with lower education. Being divorced/widowed/unmarried had a negative association with the psychological health and social relationship dimensions, whereas higher income was positively associated with QOL parameters such as psychology, social relationships and environmental factors. Self-efficacy was positively associated with all four domains of QOL. Conclusions: The present study demonstrated a moderate QOL in women with breast cancer in rural India. Young age, lack of education and being without a partner were negatively related to QOL, and employment as casual and industrial workers, high monthly family income and higher self-efficacy were positively associated with QOL. A comprehensive public health initiative is required, including social, financial and environmental support, that can provide better QOL for breast cancer survivors.