Miracle-dz/UniFAR-FTUs huggingface dataset:
A novel smart water-meter based on IoT and smartphone app for city distribution management

A novel approach to performing automated water-meter reading for update of consumption information from field to the Utility office is described in this paper. The smart metering approach proposed differs from existing commercial methodologies by making use of low cost IoT hardware and smartphone app. This scheme permits both Meter Reader as well as individual domestic / industrial consumers to use regular smartphones to perform meter reading and update to utility's portal / database for billing and payment. The proposed scheme reduces overheads on Utilities in handling meter reading and billing for water distribution in metropolitan and large urban conglomerates.
Defibrillators in Nonischemic Cardiomyopathy Treatment Evaluation

The Defibrillators in Nonischemic Cardiomyopathy Treatment Evaluation (DEFINITE) is a multicenter randomized trial. Patients will have nonischemic Cardiomyopathy (LVEF ± 35%), a history of symptomatic heart fail‐ure and spontaneous arrhythmia (> 10 PVCs/hour or nonsustained ventricular tachycardia defined as 3‐15 beats at a rate of > 120 beats/min) on Holter monitor or telemetry within the past 6 months. Patients will be randomized to an implantable cardioverter defibrillator (ICD) versus no ICD. All patients will re‐ceive standard oral medical therapy for heart failure including angiotensin converting enzyme inhibitors and β‐blockers (if tolerated). Patients will be followed for 2‐3 years. The primary endpoint will be total mortality. Quality‐of‐life and pharmacoeconomics analyses will also be performed. A registry will track patients who meet basic inclusion criteria but are not randomized. We estimate an annual total mortality of 15% at 2 years in the treatment arm that does not receive an ICD. The ICD is expected to reduce mor‐tality by 50%. Approximately 204 patients will be required in each treatment group. Twenty‐five centers will be included in a trial designed to last an estimated 4 years.
Occurrence of Salmonella serotype Typhimurium DT104 on a commercial swine farm before, during, and after depopulation and repopulation.

OBJECTIVE To determine whether depopulation-repopulation could be used to eradicate Salmonella serotype Typhimurium DT104 from a commercial swine farm in the midwestern United States. DESIGN Observational study SAMPLE POPULATION A commercial swine farm undergoing depopulation-repopulation to eliminate porcine reproductive and respiratory syndrome virus and Mycoplasma hyopneumoniae. PROCEDURE Pooled fecal samples, tissue samples, and serum samples were collected from pigs on the farm before and after depopulation-repopulation. When there were no pigs on the farm, environmental swab specimens were collected for bacterial culture. Serum was analyzed for anti-Salmonella antibodies with an indirect ELISA. Salmonella isolates obtained by bacterial culture of fecal, tissue, and environmental samples were characterized by means of serotyping, phage typing, pulsed-field gel electrophoresis (PFGE), and antimicrobial susceptibility testing. RESULTS 167 Salmonella isolates representing 9 serotypes were recovered from the farm. Results of PFGE and antimicrobial susceptibility testing suggested that S. Typhimurium DT104 strain was not eradicated from the farm. However, seroprevalence of anti-Salmonella antibodies and the percentage of pooled fecal samples positive for Salmonella spp were significantly decreased following repopulation. CONCLUSIONS AND CLINICAL RELEVANCE Results suggested that depopulation-repopulation in conjunction with stringent cleaning and disinfection, attention to biosecurity procedures, control of other diseases, and changes in feed management may reduce the occurrence of, but likely will not eliminate, Salmonella spp in commercial swine herds.
Nominal Exchange Rate Determinacy Under the Threat of Currency Counterfeiting

We study the endogenous choice to accept fiat objects as media of exchange and their implications for nominal exchange rate determination. We consider a two-country environment with two currencies which can be used to settle any transactions. However, currencies can be counterfeited at a fixed cost and the decision to counterfeit is private information. This induces equilibrium liquidity constraints on the currencies in circulation. We show that the threat of counterfeiting can pin down the nominal exchange rate even when the currencies are perfect substitutes, thus breaking the Kareken-Wallace indeterminacy result. When the two currencies are not perfect substitutes, an international currency can exist whereby one country has two currencies circulating while the other country uses only one. We also find that with appropriate fiscal policies we can enlarge the set of monetary equilibria with determinate nominal exchange rates. Finally, we show that the threat of counterfeiting can also help determine nominal exchange rates in a variety of different trading environments.
Colocalization of Androgen Binding Protein, Oxytocin Receptor, Caveolin 1 and Proliferation Marker p21 in Benign Prostate Hyperplasia

Androgen‐binding protein (ABP) and oxytocin (OT) are among the factors that control smooth muscle proliferation and tumour growth through oxytocin receptor (OTR). A close functional interaction of OTR and caveolin 1 has been shown to modulate cell growth and proliferation. We investigated samples from 10 patients (mean age 68.3) who underwent transurethral prostate resection because of benign prostate hyperplasia (BPH) by immunohistochemistry. Post‐mortem prostate samples of three young men (age 18, 28, 33) were used as controls. Tissue samples were embedded in epoxy resin and cut into serial 1 μm sections for colocalization of ABP, OTR, proliferation marker p21 and caveolin 1. ABP was found in stroma of the smooth muscle cells in all studied samples. OTR staining occurred in most of these cells in BPH while controls contained only scattered cells positive for OTR. There were no apparent differences in immunostaining for p21 while immunoreactivity for caveolin 1 was observed in most cells in BPH and only in few cells in controls. Caveolin 1 was mostly colocalized with ABP and OTR in BPH samples while controls did only occasionally show this colocalization. Our observations indicate an interaction of ABP and OTR, associated with caveolin 1, which may account in part for known non‐genomic actions of gonadal steroids. Androgen dependent prostate growth in BPH may be linked to these mechanisms.
Declining HIV rates in Uganda: due to cleaner needles, not abstinence or condoms

Public health and political authorities have ascribed the apparent decline in Ugandan HIV or AIDS rates to increased rates of sexual abstinence or condom use. However, what appears to be special about Uganda is that in the middle to late 1980s there was a growing public awareness of health care risks. Given the lack of evidence for transmission of HIV to healthy persons by penile–vaginal intercourse, the improvement in injection safety is the best candidate for declining HIV and AIDS rates.
Synthesis, structure determination and characterization by UV–Vis and IR spectroscopy of bis(diisopropylammonium) cis-dichloridobis(oxalato-κ2 O 1,O 2)stannate(IV)

In the crystal structure of the title compound, (C6H16N)2[Sn(C2O4)2Cl2], the cations are linked to the anions by N—H⋯O hydrogen bonds to generate chains along the c-axis direction. Only van der Waals interactions are observed between the chains.
PPR2263, a DYW-Subgroup Pentatricopeptide Repeat Protein, Is Required for Mitochondrial nad5 and cob Transcript Editing, Mitochondrion Biogenesis, and Maize Growth[C][W]

The work identifies maize PPR2263 and Arabidopsis thaliana MEF29 as orthologous mitochondrial RNA editing proteins, the first such orthologs shown to share target sites between a monocot and a dicot. In maize, the loss of editing of the cob transcript by PPR2263 causes the loss of a protein complex in the mitochondrial respiratory chain and ultimately slow growth of mutant plants. RNA editing plays an important role in organelle gene expression in various organisms, including flowering plants, changing the nucleotide information at precise sites. Here, we present evidence that the maize (Zea mays) nuclear gene Pentatricopeptide repeat 2263 (PPR2263) encoding a DYW domain–containing PPR protein is required for RNA editing in the mitochondrial NADH dehydrogenase5 (nad5) and cytochrome b (cob) transcripts at the nad5-1550 and cob-908 sites, respectively. Its putative ortholog, MITOCHONDRIAL EDITING FACTOR29, fulfills the same role in Arabidopsis thaliana. Both the maize and the Arabidopsis proteins show preferential localization to mitochondria but are also detected in chloroplasts. In maize, the corresponding ppr2263 mutation causes growth defects in kernels and seedlings. Embryo and endosperm growth are reduced, leading to the production of small but viable kernels. Mutant plants have narrower and shorter leaves, exhibit a strong delay in flowering time, and generally do not reach sexual maturity. Whereas mutant chloroplasts do not have major defects, mutant mitochondria lack complex III and are characterized by a compromised ultrastructure, increased transcript levels, and the induction of alternative oxidase. The results suggest that mitochondrial RNA editing at the cob-908 site is necessary for mitochondrion biogenesis, cell division, and plant growth in maize.
Gene electro‐transfer improves transduction by modifying the fate of intramuscular DNA

Intramuscular gene delivery through injection of plasmid DNA has long been considered a promising approach for safe and simple in vivo gene expression for vaccination and gene therapy purposes. Recently, intramuscular gene delivery has been improved by applying low‐voltage electric pulses after plasmid injection, a procedure that has been variably called gene electro‐transfer, in vivo electroporation or electrical stimulation. Different types of electrical treatments have been used with excellent results both in terms of transgene expression levels and immunization outcome. This approach, therefore, holds promise for safe gene delivery to animals and humans designed for non‐viral gene therapy and DNA‐based vaccination. The molecular mechanisms underlying this increment in transduction efficiency are, however, still unclear.
Reflections on the application of 13C‐MRS to research on brain metabolism

The power of 13C‐MRS lies in its unique chemical specificity, enabling detection and quantification of metabolic intermediates which would not be so readily monitored using conventional radiochemical techniques. Examples from animal studies, by examination of tissue extracts from the whole brain, brain slices and cultured cells, include observation of intermediates such as citrate and triose phosphates which have yielded novel information on neuronal/glial relationships. The use of 13C‐labelled acetate as a specific precursor for glial metabolism provided evidence in support of the view that some of the GABA produced in the brain is derived from glial glutamine. Such studies have also provided direct evidence on the contribution of anaplerotic pathways to intermediary metabolism. Analogous studies are now being performed on the human brain, where 13C‐acetate is used to quantitate the overall contribution of glial cells to intermediary metabolism, and use of 13C‐glucose enables direct calculation of rates of flux through the TCA (FTCA) and of the glutamate–glutamine cycle (FCYC), leading to the conclusion that the rate of glial recycling of glutamate accounts for some 50% of FTCA. The rate of 0.74 μmol min−1 g−1 for FTCA is compatible with PET rates of CMRglc of 0.3–0.4 μmol min−1 g−1 (since each glucose molecule yields two molecules of pyruvate entering the TCA). Our brain activation studies showed a 60% increase in FTCA, which is very similar to the increases in CBF and in CMRglc observed in PET activation studies. Copyright © 2003 John Wiley & Sons, Ltd.
Can Silent Ischemic Cerebral Lesions Affect Cognition of Parkinson's Disease Dementia?

†Background: Several studies have shown that the presence of cerebrovascular lesions may play an important role for determining the severity of the clinical symptoms of dementia. But no study to date has explored the clinical effect of cerebrovascular disease in Parkinson’s disease with dementia (PDD), although cerebrovascular disease is common causes of dementia in elderly population. Therefore we conducted this study to evaluate the relationship between silent cerebrovascular lesions and cognitive decline in PDD. Methods: Only 27 patients with PDD were chosen; 17 patients had PDD with silent cerebral ischemic lesions (PDDI) and 10 patients had PDD without silent cerebral ischemic lesions (pure PDD). These subjects received the global cognitive function testing and were all evaluated with detailed neuropsychological tests including attention, memory, language, and also the visuospatial and frontal function. Results: There were no significant differences between pure PDD and PDDI group on general cognitive functions tests. Regard to mean time duration of suffering from Parkinson motor symptoms and motor function scale, pure PDD group showed more long duration than PDDI group but there was no significant difference between two groups. Furthermore, there were not any significant differences between the two groups on detailed neuropsychological tests. Conclusions: we concluded that silent cerebrovascular lesions do not contribute to neuropsychological severity of PDD, although vascular disease is a common cause of cognitive impairment in the elderly. Thus the results of the present study suggest that factors other than cerebrovascular disease contribute to severity of PDD.
An Interprofessional Education Pilot Study for Nursing and Speech-Language Pathology Students

Background: Despite the complexity of patient care and promise of interprofessional collaboration in health professional educational programs, interprofessional education and practice implementation challenges exist. Materials and Methods: A pilot study with a nonequivalent comparison before/after design was conducted to examine undergraduate students' and graduate students' knowledge of the role of nurses and speech-language pathologists (SLPs) while working with patients diagnosed with dysphagia. All students received pre- and post-tests assessing their knowledge of the respective profession. Results: A repeated measure of analysis of variance using pre- and post-tests by group design revealed a strong and statistically significant main effect from pre- to post-testing, [F (1, 19) = 17.42, p = 0.001, and partial η2= 0.48]. Conclusions: The results indicated that students received higher scores on post-tests. This study reinforces the importance of collaboration of healthcare professionals during their professional coursework.
The Study of Vietnamese Bonechar Synthesis and its Applications in Removal Organic Color

Biochar was synthesized from two material sources such as animal waste or plant waste. In this work, biochar was synthesized going from bovine bone waste at Vietnam country, called as Vietnamese bone char (VNBC). Many steps of process to VNBC synthesis, and its surface characteristics were investigated, respectively. The applications of VNBC being as adsorbents were examined then. The results of synthesis process were obtained the VNBC product sample with optimal condition to be at temperature of 650 oC, corresponding to 120 minutes. The analysis on surface properties of VNBC indicated that the specific surface area were 120.315 m2/g, with pore diameter as 87.48 Ã… measured by BJH (Barrett,Â JoynerÂ andÂ Halenda) method. The surface morphology with the particle size measured by SEM (Scanning Electronic Spectroscopy) method was 70 nm. The composition compounds of VNBC contained calcium carbonate-hydroxyl apatite with the formula was Ca10(PO4)5.65(CO3)0.64(OH)3.45 measured by FT-IR (Fourier Transform Infrared Spectroscopy) and XRD (X-Ray Diffraction Spectroscopy) methods, respectively. In application, VNBC uses at optimal condition as an adsorbent to remove the organic color solutions for instance KMnO4 and methylene blue (MB) were considered. The results of VNBC adsorbent to remove the colored solutions measured by UV/VIS (Ultraviolet Visible spectroscopy) method are obtained with adsorption capacity of KMnO4 as from 33.51 to 46.22 mg color/g BC, and MB from 12.1 to 15.04 mg color/g BC, respectively. These results shown that VNBC were able to use making a potential adsorbent in the treatment of wastewater contained organic color in industry.
Clinical, haematological and molecular studies in patients with chromosome translocation t(7;11): a study of four Chinese patients in Taiwan

Translocation t(7;11)(p15;p15) is an uncommon but recurrent chromosome aberration in acute myeloid leukaemia (AML), which occurs mostly in oriental patients and in AML M2 or, occasionally, M4 subtype. Recently, a consistent chimaeric fusion transcript NUP98‐HOXA9 was found in several cases of t(7;11). Four AML cases with the chromosome abnormality in Taiwan are described. They were all adults with ages ranging from 30 to 41 years (median 36 years). Three of them were diagnosed as having AML M2; the remaining one as M4. Marked dyserythropoiesis was demonstrated in two patients. All four patients showed pan‐myeloid antigen CD13 on the leukaemic cells, but none coexpressed lymphocyte‐associated antigens and neither of the two patients studied for CD34 expression had positive staining. NUP98‐HOXA9 fusion transcript was detected in both patients who had molecular analysis and the breakpoints on chromosome 11 and 7 respectively were similar to those previously reported. They all received conventional induction chemotherapy, but only one achieved a complete remission (CR) with short duration. This study and others reported in the literature suggest a racial or geographical predisposition among oriental patients to AML with t(7;11) and that this is associated with a poor prognosis. The molecular detection of NUP98‐HOXA9 fusion transcript would be a useful method for the diagnosis of t(7;11) and also for monitoring disease status after treatment.
Development of a biodegradable membrane to be used with skin explants for full thickness skin defect reconstruction.

27 Chapter 1 . 30 INTRODUCTION . 30 1.1 Structure of Human Skin . 31 1.1.1 Epidermis . 32 1.1.2 Basement Membrane . 33 1.1.3 Rete ridges . 34 1.1.4 Dermis . 37 1.1. 5 Hypodermis . 38 1.1. 6 Blood Supply to the Skin . 38 1.2 CHARACTERISTICS OF CELLS USED TO POPULATE THE ELECTROSPUN SCAFFOLDS . 39 1.2. 1 Keratinocyte biology . 39 1.2. 2 Fibroblast Biology . 40 1.2. 3 Epidermal Stem Cell Biology . 42 1.2. 4 The concept of Skin Explants being used to regenerate an epidermis . 44 1.3 THE CLINICAL NEED FOR SKIN REPLACEMENT . 45 1.4 APPROACHES TO SKIN RECONSTRUCTION . 47 1.4.
Everlasting Friends and Enemies? Finnish University Personnel’s Perceptions of Internal Quality Assurance in 2010 and 2017

ABSTRACT Even though quality assurance has played a role in European higher education for decades by now, it is still a topic of great discord. While several studies have focused on the initiation phase of quality assurance, little attention has been paid to the question on how attitudes towards quality assurance in higher education change over time. This study compares the attitudes of Finnish university personnel using data from 2010 and 2017. The results show that personnel experience quality assurance as slightly better in 2017 than in 2010, while differences concerning gender, personnel group and type of university persist. The findings underline the importance of implementing quality assurance in a stakeholder-specific way.
Analysis of localization and reorganization of germ plasm in Xenopus transgenic line with fluorescence‐labeled mitochondria

Germ plasm is found in germ‐line cells of Xenopus and thought to include the determinant of primordial germ cells (PGCs). As mitochondria is abundant in germ plasm, vital staining of mitochondria was used to analyze the movement and function of germ plasm; however, its application was limited in early cleavage embryos. We made transgenic Xenopus, harboring enhanced green fluorescent protein (EGFP) fused to the mitochondria transport signal (Dria‐line). Germ plasm with EGFP‐labeled mitochondria was clearly distinguishable from the other cytoplasm, and retained mostly during one generation of germ‐line cells in Dria‐line females. Using the Dria‐line, we show that germ plasm is reorganized from near the cell membrane to the perinuclear space at St. 9, dependent on the microtubule system.
On the Value Relevance of Finance's Cash Flow and Accounting's Accruals: Empirical Evidence from Egypt

We adhere to the value relevance approach to accounting capital markets research in order to investigate the accounting information environment in Egypt. Our main objective is to learn of the set of accounting information that can be considered value relevant in the Egyptian equity market. Particularly, we test the claim frequently encountered in the authoritative finance literature (e.g., Brealey and Myers, 2002; Copeland, Weston, and Shastri, 2005) that, accounting accruals are noisy and should not matter in equity valuation since the main concern is with expectations of future cash flows. However, unlike prior literature that investigates the same claim based exclusively on Ohlson's (1995) unbiased accounting model or one of its derivatives that allow for accounting conservatism such as (Ohlson, 1999) (e.g., Barth, Beaver, Hand, and Landsman, 1999), we design the tests based on Pope and Wang's (2005) residual income specification. Pope and Wang's basic equity value specification assumes mainly clean surplus accounting along with Modigliani and Miller's (1961) dividend policy irrelevance. Unlike Ohlson's, Pope and Wang's doesn't assume no-arbitrage pricing or specific linear abnormal earnings dynamics structure. Pope and Wang's specification also explicitly links the information role of accounting measures in valuation to their informational roles in forecasting abnormal earnings. Ultimately, the analysis based on Pope and Wang's specification allows us to [1] report on the explanatory power of a typical residual income valuation model in Egypt, [2] test the constraint that, both accounting accruals and cash flow aggregate in valuation (and in forecasting abnormal earnings), [3] test if the summary accounting measures in Egypt accurately replicate the economic characteristics of the underlying constructs they purport to be measuring, and [4] report a parameter representing the extent of accounting conservatism in the spirit of (Feltham and Ohlson, 1995). Our analysis in this fashion extends the value relevance literature by estimating Pope and Wang's specification employing data from the Egyptian stock market. As opposed to developed markets, it is far less obvious to what extent Egyptian accounting information is replicated in equity values. It is not also clear in Egypt what kind of accounting information should be employed for purposes of valuation and fundamental analysis.
Teachers: technology, change and resistance

This chapter explores the way in which a culture of educational technology-related policy and curriculum change has arguably resulted in minimal improvement in teaching and learning. Moreover, it is argued that such a culture of change has instead simply increased teacher disengagement and thereby resulted in teachers being erroneously labelled by polichy actors, administrators and technology enthusiasts as 'resistant' to change, 'luddites' and 'risk averse'. Accordingly, this chapter challenges these simplistic labels, and offers a more critical perspective of how and why teachers (dis)engage with technology.