Miracle-dz/UniFAR-FTUs huggingface dataset:
Radiotherapy in non-small-cell lung cancer : changing perspectives in palliative care

Kramer GWPM, Gans SJ, Ullmann EF. “External re-irradiation of non small cell lung cancer (NSCLC); a pilot study”. Lung Cancer 1994;11(S1):135,517#. van Zandwijk N, Crino L, Kramer GW et al. Phase II study of gemcitabine plus cisplatin as induction regimen for patientw with stage IIIA non-small cell lung cancer by the EORTC Lung Cancer Cooperative Group (EORTC 08955) Lung Cancer 1998;17(S2):486a,1799#. Kramer GWPM, Gans SJ, Ullmann EF, Leer J-W. Reirradiation with external beam treatment of Non-Small Cell Lung Carcinoma. Radiotherapy & Oncol 2002;64:S255,P859. Kramer GWPM. Eindrapportage van de landelijke studie naar het effect van bestraling met verschillende bestralingsschema’s voor het niet-kleincellig longcarcinoom. Verenigingsverslag NTvG 2003;147(20):992. Kramer GWPM, Wanders SL, Noordijk EM, Vonk EJA, Uitterhoeve ALJ, Bussink J, van de Leest AHD,. van Houwelingen JC, van den Hout WB, Leer J-WH. Randomized Dutch National study of the effect of irradiation with different treatment schemes in the palliation of Non-Small-Cell Lung-Cancer (NSCLC). Lung Cancer 2003;41(S2):S38. P. van Schil E, van Meerbeeck JP, . KrameGr, Splinter T, Legrand C, O’brien M, Giaccone G, Manegold C, van Zandwijk N. Surgery after induction chemotherapy: Morbidity and mortality in the first 100 patients of the surgery arm of EORTC 08941 trial. Lung Cancer 2003;Vol 41(S2):S45. van Meerbeeck JP, Kramer GWPM, van Schil PEY, Legrand C, O’brien M, Manegold C, Giaccone G, van Zandwijk N, Splinter TAW. Induction chemotherapy (CT) in stage IIIA-N2 non-small cell lung cancer (NSCLC): an analysis of different regimens used in EORTC 08941. Lung Cancer 2003;41(S2):S79. Kramer G, van Meerbeeck J, van Schil P, Uitterhoeve L, Smit E, Schramel F, Biesma B, Tjan-Heijnen V, Legrand C, van Zandwijk N, Splinter T, Giaccone G, on behalf of EORTC-Lung Cancer Group. Quality Assurance Review of Thoracic Radiotherapy in EORTC 08941: A randomized trial of Surgery versus Thoracic Radiotherapy in patients with stage IIIA Non-Small-Cell Lung Cancer (NSCLC) after response to induction chemotherapy. Lung Cancer 2005;49(S2):S79 PD-045.
Role of CTGF and TNF on fibrosis in muscular dystrophy

The Duchenne Muscular Dystrophy (DMD) is an X-linked disease characterized by progressive damage in the muscle due to the absence of the dystrophin protein. Fibrosis, the excessive accumulation of extracellular matrix (ECM) proteins, is also present in the muscle of DMD patients and several animal models (such as the mdx mice). Among the factors that induce fibrosis are Transforming Growth Factor type β (TGF-β) and Connective Tissue Growth Factor (CTGF), the latter being a target of the TGF-β/SMAD signaling pathway and is the responsible for the profibrotic effects of TGF-β and are augmented in fibrosis tissues. Little is known about the regulation of the expression of CTGF mediated by TGF-β in muscle cells. In here, we described a novel SMAD Binding Element (SBE) located in the 5’ UTR region of the CTGF gene important for the TGF-β mediated expression of CTGF in myoblasts. In addition, our results suggest that additional transcription factor binding sites present in the 5’ UTR of the CTGF gene are important for this expression. On the other hand, the Tumor Necrosis Factor (TNF) is an inflammatory cytokine that is present in DMD muscles and is responsible for muscle necrosis and inflammatory cell infiltration. In this study, we show that the increased expression of the soluble TNF Receptor I by electrotransfer (ET) in the tibialis anterior muscle attenuates inflammation, damage and fibrosis in the skeletal muscle of the mdx mice. In addition, we found increased muscle strength in the mdx mice. Therefore, we propose that ET could be used as an efficient anti-TNF therapy for treating muscle dystrophies.
A Comparative Study On The Location Of The Mandibular Foramen In Panoramic Radiographs Of Normal Occlusion and Mandibular Prognathism

하악공(mandibular foramen)은 하악지(mandibular ramus)의 내면 중앙부에 위치한 구멍으로 하악골 내면을 지나는 관인 하악관(mandibular canal)이 이 곳에서 시작 되어 이공(mental foramen)에서 분지를 내며 하악 결합 부위까지 연결되는 해부학적 구조물로 그 내부로는 삼차신 경 하악지(mandibular branch of trigerminal nerve)의 한 분지인 하치조 신경 및 혈관(inferior alveolar nerve and atery)이 흐르고 있으며 하악의 치아 및 점막에 분포 한다. 하악공의 전상방에는 하악소설(mandibular lingula)이라 불리는 돌기가 존재하며 하악공 대부분 유치열기에 는 교합평면 연장선상 하방에 위치하다가 성인이 되면서 거 의 연장선과 일치하게 된다. 하악골에서 하악공의 해부학적 위치는 치과 영역에서 매 우 중요하다. 특히 시술중의 동통 감소를 위한 하치조 신경 전달 마취 시의 지침이 되는 해부학적 구조로 뿐만 아니라 많이 시술되고 있는 하악골 상행지 시상 분할 골 절단술 (sagital split ramus osteotomy) 또는 수직 골 절단술 (vertical ramus osteotomy) 등의 악골 기형의 수술은 대 대한악안면성형재건외과학회지: Vol. 24, No. 3, 2002
Choosers or losers? Influences on young people's choices about drugs in inner-city Dublin.

This research was undertaken against a background of increased drug use, and heightened concern for young people growing up in area where drug use is concentrated. This report aims to examine the use and non-use of drugs by young people aged 15-19 years in a Dublin inner-city community considered to be 'high risk' for problem drug use. The role of choice and decision-making in drug use are key issues addressed in this report. Young people were recruited from within the community following a period of prolonged engagement by the researcher. A qualitative approach consisting of individual in-depth interviews and focus group discussions was utilised. 57 young people were interviewed individually and 24 took part in the focus group discussion. The study findings highlight the importance of considering the perspectives of young people in the planning and implementation of drug prevention strategies. The study found that there is a need to target high-risk groups, alternative and innovative strategies should be employed to reach difficult to reach groups. Specially tailored school based drugs education programmes and greater inter-agency co-operation between health services, youth workers educational and social services etc. need to be developed. Harm reduction education and treatment interventions were also recommended.
Analysis of factors associated with coaching efficacy among New Mexico high school coaches

The purpose of the study was to analyze various factors associated with coaching efficacy among New Mexico high school coaches. The study examined their coaching efficacy from three different perspectives. First, the study determined whether coaching efficacy differ depending on sociocultural and organizational factors such as coach gender/ethnicity, school size, and type of school assignment. Second, the study examined which sources of efficacy specifically predict coaching efficacy. Third, the study identified the best set of efficacy sources predicting coaching efficacy. The sources of efficacy initially identified in this study were coaching experience, playing experience, prior success, perceived athlete ability, perceived athlete improvement, and perceived social support. The target population of the study was New Mexico high school team sports head coaches because the coaching efficacy measurement (i.e., Coaching Efficacy Scale IIHigh School Team) was best applicable to team sports rather than individual sports and
Decoupled Certainty-Driven Consistency Loss for Semi-supervised Learning

One of the successful approaches in semi-supervised learning is based on the consistency regularization. Typically, a student model is trained to be consistent with teacher prediction for the inputs under different perturbations. To be successful, the prediction targets given by teacher should have good quality, otherwise the student can be misled by teacher. Unfortunately, existing methods do not assess the quality of the teacher targets. In this paper, we propose a novel Certainty-driven Consistency Loss (CCL) that exploits the predictive uncertainty in the consistency loss to let the student dynamically learn from reliable targets. Specifically, we propose two approaches, i.e. Filtering CCL and Temperature CCL to either filter out uncertain predictions or pay less attention on them in the consistency regularization. We further introduce a novel decoupled framework to encourage model difference. Experimental results on SVHN, CIFAR-10, and CIFAR-100 demonstrate the advantages of our method over a few existing methods.
Technology Acceptance Models and Adoption of Innovations: A Literature Review

This paper reviews the main models and theories that used in previous studies to study the adoption of innovations in different areas such as online banking, mobile banking, E-learning and E-health care systems. Despite of the increasing development of technology and its incorporation into users’ privacy and professional life, a decision regarding to adopt or reject it remains an open question. Thus, a well thought-of amount of research work dealing with the technology acceptance models was conducted among various disciplines. Such research work originated in the psychological theories such as theory of reasoned action and theory of planned behaviour. The models Technology acceptance have evolved to become a mix of psychology, sociology and Information Technology. These models assist in understanding predictors of human behavior toward potential adoption or rejection of the innovation / technology. The overall aim of this paper is to provide an up-to-date, well-researched resource of past and current references to related literature of technology acceptance models and to identify possible directions for future research in this regard. The paper presents a comprehensive literature review of the technology acceptance models and its applications across different areas and to highlight the main factors that influence the adoption of new technologies. The previous studies have been selected and classified according to which model they used to study the adoption / acceptance of specific technology. In order to identify relevant studies which addressed the main dominant technology acceptance models, a structured approach followed by searching on particular keyword(s) in the leading journal databases, then selection of publications with a matching criteria and quick scan of the selected studies by reading their titles, abstracts, and full text to select those relevant to technology acceptance models research; and finally detailed process of reading and analyzing a full text of the selected research publications.
Education of Chinese children in Britain and the USA

Part 1 Issues and methodology: contemporary Chinese communities in London, San Francisco and New York City. Part 2 Education provision for Chinese children in the UK: analysis of Chinese children's problems in Britain problems of Chinese pupils in the British context - some case studies mother tongue teaching in the Chinese community Chinese language education in British state schools. Part 3 Education provision for Chinese children in the USA: problems of Chinese-American pupils in San Francisco and New York City education initiatives of the Chinese in the United States Chinese bilingual-bicultural education programmes in American public schools. Appendices: questionnaire A questionnaire B summary of subjects interviewed schools/institutions/Chinese families interviewed Chinese linguistic problems among Chinese pupils attending part-time Chinese classes in Britain.
Estudo da variabilidade dos parâmetros derivados do tensor de difusão na doença de Parkinson e no tremor essencial

Parkinson’s Disease (PD) and Essential Tremor (ET) are two neurological, chronic and progressive diseases. Worldwide, it is estimated that PD affects about 1% of the population over 65 years old and that ET affects up to 5% of the population with over 40 years of age. The PD is the main differential diagnosis of ET, and the diagnosis is based on clinical criteria whose sensitivity and specificity for early stage disease are low. As such, it is necessary to identify biomarkers to aid with the diagnosis of these diseases and their differentiation. Using the imaging technique of diffusion tensor imaging (DTI) and the method of analysis in regions of interest, this study aimed to evaluate whether fractional anisotropy (FA) and mean diffusivity (MD) values estimated in 11 neuroanatomical regions are good early biomarkers for PD and ET. It also aimed to study the reproducibility of these measurements, their evolution within 1 year and if in patients with an initial diagnosis of PD these values were influenced by anti-parkinsonian medication. As a result of this study, changes were found in FA values of the middle cerebellar peduncle and in the values of MD at the lenticular nucleus (NL), superior cerebellar peduncle and dentate nucleus level. FA and MD values in the substantia nigra, caudate nucleus, NL, were found to be satisfactorily reproducible, not to change with anti-parkinsonian drugs, and in general not to vary significantly within 1 year. These results show that the measurement of FA and MD values in these neuroanatomical regions may be potential biomarkers to aid clinicians in early and differential diagnosis of PD and ET, and help monitoring the progression of these diseases.
Measuring Customer Experiences : A Text-Based and Pictorial Scale

Providing superior customer experiences has become a strategic priority for companies. However, companies and researchers lack a measure that quantifies customer experience (CX) as a multi-dimensional construct in today’s omni-channel environment, predicts crucial outcomes (e.g., customer satisfaction and loyalty), and measures CX in an accurate but efficient way (e.g., in mobile surveys). This has led to persistent difficulties for companies to manage customer interactions. To address these drawbacks, this paper provides two reliable and valid CX scales: a textbased and a pictorial scale. While research can apply the text-based scale, the pictorial scale especially enables companies to track CX efficiently.
Analisis Pengaruh Faktor-Faktor terhadap Income Smoothing dengan Gender Sebagai Variabel Moderator pada Emiten Perbankan

Management can intervene to the process of preparation of financial statements for external parties by leveling, raising, or lowering the reported profit. One pattern of earnings management is income smoothing, that is leveling reported profit in order to reduce fluctuations of earnings. The purpose of this study is to evaluate whether the factors of Return on Assets (ROA), Debt to Equity Ratio (DER), as well as Net Interest Margin (NIM) affect income smoothing using gender as moderator variable, by observing the proportion of women in boards. The samples were 26 banks listed on IDX, 2008-2012 period, analyzed by using the SPSS multiple linear regression testing and regression models moderation. We found that ROA, NIM, DER, moderated by gender variable significantly affect income smoothing. Partial test also showed that with gender as moderator, ROA and NIM significantly influence
Climate change vulnerability assessment for Can Tho city by a set of indicators

Purpose The city of Can Tho, located on Vietnam’s Mekong Delta, has been identified as one of the nation’s most vulnerable sites for adverse climate change-induced impacts. Can Tho’s policymakers are faced with tackling these challenges but lack the necessary tools and funds to properly address the situation. The study aims to develop a set of indicators to assess the degree of climate change vulnerability so that policymakers can determine which of Can Tho’s districts are most in need of attention, and then propose the best options for climate change adaptation activities. Design/methodology/approach The indicators, including quantifications of exposure, sensitivity and adaptive capacity, were categorized in three tiers, from 1 to 3, to reflect their importance with regard to the situation. The higher tier indicators comprised a number of lower tier indicators, which were developed based on real-life, practical situations at the local level. Findings The results showed that the Thoi Lai District, with a vulnerability indicator estimated at 0.59, is more vulnerable to the impacts of climate change than other districts because of its lower adaptive capacity and higher sensitivity. In contrast, Ninh Kieu District’s climate change indicator of 0.24 demonstrates it has higher resilience to climate change impacts. Originality/value This study showed that the set of indicators developed provides a promising approach for supporting local policymakers in Can Tho to actively respond to climate change-related challenges, and that this approach has the potential to be upscaled for other cities in Vietnam.
Understanding the Lived Experiences of Women with Spinal Cord Injury Who Undergo Urinary Diversion Surgery

Understanding the Lived Experiences of Women with Spinal Cord Injury who Undergo Urinary Diversion Surgery by Sukhpinder Dhillon Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Clinical Psychology Walden University April 2015 Abstract Following spinal cord injury (SCI), bladder management is of primary importance. As an activity of daily living (ADL), it affects community integration and quality of life (QOL). Women with SCI have neurogenic bladders that require self-catheterization, but they are unable to catheterize the native urethra, thus making bladder management physically and emotionally challenging. The purpose of this study was to understand the experiences ofFollowing spinal cord injury (SCI), bladder management is of primary importance. As an activity of daily living (ADL), it affects community integration and quality of life (QOL). Women with SCI have neurogenic bladders that require self-catheterization, but they are unable to catheterize the native urethra, thus making bladder management physically and emotionally challenging. The purpose of this study was to understand the experiences of women with SCI who undergo urinary diversion surgery for bladder management. Qualitative data were collected using semistructured interviews from 10 women with SCI after urinary diversion surgery for bladder management. Qualitative Nvivo analysis of interview data was based on cognitive adaptation theory, which emphasizes adaptation to life-threatening events. Analysis showed improved quality of life among these 10 women, with improvements in independence, convenience, aesthetics, confidence, and sexuality. The women’s lived experiences also showed enhanced privacy, dignity, normalcy, and safety. The lack of awareness in health care workers to offer this procedure was universally highlighted by participants. The social change implications include the need to advocate for women with SCI with bladder management needs who are unaware of this surgery option. Understanding the bladder management needs of women with SCI may help this population make choices for a better quality of life. Understanding the Lived Experiences of Women with Spinal Cord Injury Who Undergo Urinary Diversion Surgery By Sukhpinder Dhillon Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Clinical Psychology
Spatio-temporal modeling of PM2.5 concentrations with missing data problem: a case study in Beijing, China

ABSTRACT One of the major challenges in conducting epidemiological studies of air pollution and health is the difficulty of estimating the degree of exposure accurately. Fine particulate matter (PM2.5) concentrations vary in space and time, which are difficult to estimate in rural, suburban and smaller urban areas due to the sparsity of the ground monitoring network. Satellite retrieved aerosol optical depth (AOD) has been increasingly used as a proxy of ground PM2.5 observations, although it suffers from non-trivial missing data problems. To address these issues, we developed a multi-stage statistical model in which daily PM2.5 concentrations can be obtained with complete spatial coverage. The model consists of three stages – an inverse probability weighting scheme to correct non-random missing patterns of AOD values, a spatio-temporal linear mixed effect model to account for the spatially and temporally varying PM2.5-AOD relationships, and a gap-filling model based on the integrated nested Laplace approximation-stochastic partial differential equations (INLA-SPDE). Good model performance was achieved from out-of-sample validation as shown in R2 of 0.93 and root mean square error of 9.64 μg/m3. The results indicated that the multi-stage PM2.5 prediction model proposed in the present study yielded highly accurate predictions, while gaining computational efficiency from the INLA-SPDE.
Forecasting Foreign Exchange Rate And Consumer Price Index With Arima Model: The Case Of Turkey

The high and increasing rate of uncertainty in the world’s Foreign Exchange Market (FEM) is one that poses a great concern to the market players, traders and policy makers. There is need to come up with reliable and sophisticated models foreign exchange rate and its determinants in order to predict their future values hence reduce the risks. This paper makes use of the Autoregressive Integrated Moving Average (ARIMA) model to forecast the foreign exchange rate of Turkey and inflation a major determinant of foreign exchange rate. This paper provides that ARIMA(3,1,3) is the best ARIMA model for forecasting foreign exchange rate of Turkey and that ARIMA(1,1,4) is the best ARIMA model for forecasting Turkey’s inflation (CPI). The paper also postulates that ceteris Paribas the foreign exchange rate of the lira against the dollar will be stable in the short run future. However, with the passage of time the suggested model of forecasting foreign exchange rate and inflation of Turkey should always be updated with current data. ACF, PACF, AIC and BIC together with forecasting performance measures like MAE, MAPE, Bias proportion, RMSE and Theil U statistics are very useful in the process of best model selection.
Regularly varying functions in the theory of simple branching processes

It is demonstrated for the non-critical and the explosive cases of the simple Bienaymé-Galton-Watson (B. G. W.) process (with and without immigration) that there exists a natural and intimate connection between regularly varying function theory and the asymptotic structure of the limit laws and corresponding norming constants. A similar fact had been demonstrated in connection with their invariant measures in [22]. This earlier study is complemented here by a similar analysis of the process where immigration occurs only at points of “emptiness” of the B. G. W. process.
The Contrasting Importance of Quality of Life and Quality of Business for Domestic and International Migrants

We examine whether bilateral regional migration flows are driven by the city’s quality of life (QL) or quality of business (QB). The QL and QB measures are constructed using (quality-adjusted) rents and wages in each city. QL and QB reflect the willingness to pay of households and firms, respectively, for local amenities. The measures are constructed for 31 urban areas in New Zealand using five-yearly census data covering 1986 to 2013. We adopt a gravity model of regional migration – augmented by destination and origin QL and QB – to model bilateral flows of working-age migrants (post tertiary education and pre-retirement age). We also model flows between urban and rural areas and flows for the urban areas to and from overseas locations. We find different attractors for international versus domestic migrants according to the type of city amenity. International migrants are more attracted to cities with productive amenities whereas domestic migrants are more attracted to places with consumption amenities. Thus, in deciding on the type of city amenity to enhance, city officials implicitly choose the type of migrant that they attract as well as the type of city that may result.