Miracle-dz/UniFAR-FTUs huggingface dataset:
Investigation of views on breast cancer among Chinese women in the UK

Breast cancer is increasingly threatening the health of Chinese women. However, little is known about beliefs, attitudes or health practice related to breast cancer among Chinese women in the UK, which means that it is difficult for health professionals to provide evidence-based services to them.Using a triangulation research design, this study investigated the views on breast cancer among Chinese women in the UK. Moreover, factors influencing their views and the factors potentially threatening Chinese women? s breast health were also examined. Chinese women who accessed the National Health Service (NHS) in the UK for primary care and were aged from 50 to 70 years were targeted. Twenty-two semi-structured interviews were conducted initially. Based on interview findings, a questionnaire was developed and a questionnaire-based survey was undertaken in a larger population. The findings showed that although negative views on breast cancer were held by the majority of the Chinese women, most women engaged in a healthy lifestyle and actively attended breast screening in order to promote health and prevent breast cancer. Breast cancer views were significantly influenced by the extent to which these Chinese women had been in contact with western culture. Chinese women who were more acculturated to western culture were more likely to hold positive views on breast cancer. Two factors potentially threatened Chinese women? s breast health, which were lack of knowledge on breast and barriers to accessing health services. In order to promote early detection, practice nurses in communities need to develop culturally sensitive educational intervention to improve Chinese women? s knowledge on breast cancer, in particular on warning signs and risk factors. In addition, barriers to accessing health services need to be tackled. In particular, interpretation services should be provided to those with limited English proficiency.
Redox Triggering of Podocyte NLRP3 Inflammasomes and Glomerular Injury in Hyperhomocysteinemia

REDOX TRIGGERING OF PODOCYTE NLRP3 INFLAMMASOMES AND GLOMERULAR INJURY IN HYPERHOMOCYSTEINEMIA By Justine M. Abais A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University Virginia Commonwealth University, 2014 Major Director: Pin-Lan Li, MD, PhD, Professor, Pharmacology and Toxicology Hyperhomocysteinemia (hHcys), an important pathogenic factor contributing to the progression of end-stage renal disease (ESRD), has been shown to activate NOD-like receptor protein 3 (NLRP3) inflammasomes and cause podocyte dysfunction and glomerular sclerosis. hHcys induces aggregation of the three inflammasome components – NLRP3, apoptosis-associated speck-like protein (ASC), and caspase-1 – and its activation is indicated by increased caspase-1 activity and secretion of interleukin-1β (IL-1β). The aims of the present study sought to elucidate the role of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-mediated redox signaling in hHcys-induced NLRP3 inflammasome activation, to dissect the contribution of common endogenous reactive oxygen species (ROS) including superoxide (O2 •− ), hydrogen peroxide (H2O2), peroxynitrite (ONOO − ), and hydroxyl radical ( • OH), and to explore the molecular mechanisms by which the NLRP3 inflammasome senses changes in oxidative stress through thioredoxin-interacting protein (TXNIP). Specific inhibition of the gp91 phox subunit of NADPH oxidase markedly reduced Hcys-induced caspase-1 activity and IL-1β production in cultured podocytes. Concurrently, gp91 phox−/− or administration of a gp91ds-tat peptide also exhibited diminished glomerular inflammasome formation and activation in mice fed a folatefree (FF) diet to induce hyperhomocysteinemia and displayed glomerular protection as shown by
Psychotropic Drug Usage and Human Behaviour During Fire Emergencies

Relatively little is known about the impact psychotropic drugs, particularly sedatives, have on human behaviour in a residential fire emergency. Two separate but related avenues of investigation were conducted to explore human behaviour in fire when under the influence of psychotropic drugs. In Study One the efficacy of current and alternative smoke alarm signals was tested after the consumption of hypnotics. A supplementary objective was to examine the relationship between sleep quality and arousal thresholds. Study Two retrospectively analysed an Australian database of fire fatalities using advanced algorithmic modelling techniques to determine: (a) if users of psychotropics and hypnotics were overrepresented in the Australian fire fatality statistics; and (b) the relationship between psychotropic drug consumption and a number of behavioural, environmental, and demographic risk factors. The research provided new, important evidence revealing an uncomfortably high level of risk to users of psychotropic drugs, particularly hypnotics, in a residential fire context. This was the first time psychoactive drug usage had been considered in such detail in the international literature.
The PKU Paradox: A Short History of a Genetic Disease

In a lifetime of practice, most physicians will never encounter a single case of PKU. Yet every physician in the industrialized world learns about the disease in medical school and, since the early 1960s, the newborn heel stick test for PKU has been mandatory in many countries. Diane B. Paul and Jeffrey P. Brosco's beautifully written book explains this paradox. PKU (phenylketonuria) is a genetic disorder that causes severe cognitive impairment if it is not detected and treated with a strict and difficult diet. Programs to detect PKU and start treatment early are deservedly considered a public health success story. Some have traded on this success to urge expanded newborn screening, defend basic research in genetics, and confront proponents of genetic determinism. In this context, treatment for PKU is typically represented as a simple matter of adhering to a low-phenylalanine diet. In reality, the challenges of living with PKU are daunting. In this first general history of PKU, a historian and a pediatrician explore how a rare genetic disease became the object of an unprecedented system for routine testing. The PKU Paradox is informed by interviews with scientists, clinicians, policymakers, and individuals who live with the disease. The questions it raises touch on ongoing controversies about newborn screening and what happens to blood samples collected at birth.
Energy-Switching Using Lévy Processes - An Application to Canadian and North American Data

The Paris agreement in 2016 marks a global effort to limit the increase in temperature. In that spirit, the Federal Government of Canada introduced a carbon tax to reduce greenhouse gas emissions. The main goal of this paper is to define the correct approach to carbon pricing. Following the method, introduce by Goutte and Chevalier (2015), we define the carbon price as the necessary tax to incite electricity producers to switch from coal to natural gas. The novelty of this paper is that we use this method for Alberta and North America. In addition, we consider the case of switching from natural gas to wind as a potential new approach to carbon pricing. After reviewing the two methods, we model prices under three stochastic procedures: Levy Normal Inverse Gaussian (NIG), Levy Normal and Heston model. Finally, we generalize our empirical technique to oil, natural gas and coal individually. The main finding of this article is that the Levy NIG outperforms the Levy Normal and Heston as it is able to take into account the jumpy and volatile nature of energy prices.
Neuropsychiatri synptoms in auto-immune encephalopathies - a clinician's guide

Background: The spectrum of central nervous system autoimmune disorders has recently expanded with the discovery of disorders associated with antibodies directed against the neuronal membrane surface. Although many of these disorders have an underlying malignancy and present with signs of dysfunction of the limbic system (paraneoplastic limbic encephalitis, PLE), a high proportion of cases is non-paraneoplastic. They may occur with milder symptoms, and present no abnormalities in the exams usually used in the investigation of PLE. A striking number of cases may be misdiagnosed as primary psychiatric or other neurological disorders. This paper aims to review the current knowledge on this topic, and provide physicians with an updated text on the neuropsychiatric presentation, diagnostic approach and current management of autoimmune encephalopathies.
EDC Machine Implementation Model in Traditional Market As Shopping Tourism Icon in Yogyakarta

Nowadays, in the technology and global era, people need easiness and simplicity in all things, including in financial transaction. One of the facilities which support financial transaction is banking EDC machine. Many banking companies are already deploying EDC machines in traditional market merchants. There is a traditional market that relatively big and already known as shopping tourism icon in Yogyakarta, that is Beringharjo. The number of transactions and sales volume that occur in this market is estimated reach out until billion rupiahs. However, there are some merchants that still enjoy doing transaction by cash and reluctant to use the EDC machine because of the same reasons. The aims of this research are 1) To find out the criteria that prioritized by merchants as considerations to use EDC machine 2)To construct the EDC machine implementation model at Yogyakarta shopping tourism traditional market. The model used in this research is the AHP (Analytical Hierarchy Process) model. The result of this research shows us that the order of criteria or factors that influence the traditional merchants’ acceptance of the use of EDC (Electronic Data Capture) machines in traditional shopping tourism icons in Yogyakarta are security, usability, and convenience where the security factor has the greatest weight. The analysis shows that overall, the merchant will consider the security, usability and convenience criteria based on the sub-criteria with the following weighting order; Turnover, Age, Features and shape of the machine, Technical training on machine use, Personal attitude/opinion, Socialization from related institutions, Influence of others.
Effect of flow separation of TiO2 nanofluid on heat transfer in the annular space of two concentric cylinders

In the wake of energy crises, the researchers are encouraged to explore new ways of enhancement in the thermal performance of heat exchanging equipment. In the current research, the SST k-? model and finite volume method were employed to augment heat transfer into the separation flow of TiO2 nanofluid in the annular space of two concentric cylinders. In the present investigation TiO2 nanoparticles of volume fractions, 0.5%-2% at Reynolds number range of 10000-40000, and contraction ratios from 1 to 2 were considered at constant heat flux boundary condition. Simulation results reveal that the highest enhancement in the heat transfer coefficient is corresponding to the annular pipe with a contraction ratio of 2 due to the generated re-circulation flow zone that begins after the separation point on the wall. Further, the surface heat transfer coefficient enhances with the increase of nanoparticles volume fraction and Reynolds number. The velocity distribution profile before and after the steps reveals that increasing the height of the step and Reynolds number, re-circulation regions also increases. Numerical results indicate that the highest pressure drop occurs at the Re = 40000 and contraction ratio of 2.
A Blueprint for Integrating ESG into Equity Portfolios

ESG offers a source of new and potentially valuable information for investors, impacting both potential returns and risk. Growing data availability has created the opportunity to integrate ESG into equity portfolios for a variety of investment processes, for both indexing and active management. In this paper, we provide an overview of the current data landscape and several popular methods for integrating ESG. A main challenge is that ESG data collection and aggregation methods can vary significantly across providers, leading to very different ratings for the same company. If the data issues are properly addressed, integrating ESG has important potential benefits for investors. Our “blueprint” lays out a path for any investment manager seeking to understand how ESG fits into their investment process.
PENGARUH PRAKTIK SOCIAL NETWORKING, KEPERCAYAAN MEREK DAN LOYALITAS MEREK PADA KOMUNITAS MEREK ONLINE

The devolepment of internet made the brand community move to online activities by using a social media chat group platform. This study aims to examine the relationship between social networking and brand trust on brand loyalty in online brand community. Data were collected through a questionnaire of 150 respondents. Through SEM analysis (PLS), the results show that social networking has a positive effect on brand trust and trust mediates the relationship between social networking and brand. This finding implies that brand community must pay attention to social networking activities that can increase brand trust and brand loyalty. Companies and communities need to think about how to develop strong relationships and bonds between members so that members feel the value of the brand and build strong commitment with the brand Key words: Online-based brand community, social networking, brand trust, brand loyalty, partial least square
Accepting Your Power to Heal: The Personal Practice of Therapeutic Touch

Since 1972, Dolores Krieger has taught Therapeutic Touch to thousands of health professionals around the world. In Accepting Your Power to Heal, she now shows all of ushow to master this powerful energetic healing practice. Krieger points out that while this is not a "miracle cure," Therapeutic Touch has proven to be safe and helpful in the treatment of a variety of conditions from PMS, headaches, burns, and bone fractures to asthma, reproductive problems, cancer, and AIDS. She encourages us to acknowledge our own innate healing abilities and provides experiential exercises to teach us the basic Therapeutic Touch techniques. The miracle, if there is one, is that we can all participate in the healing process and help our friends, partners, families, and even pets to feel better.
Structural Finite Element Software Coupling Using Adapter Elements

: This paper describes a versatile and computationally efficient method for coupling several finite element analysis (FEA) programs together so that the unique modeling and analysis capabilities of each code can be utilized simultaneously to simulate the static or dynamic response of a complete numerical system. An arbitrary number of finite element analysis software packages can be coupled by adding two special types of elements, namely generic and adapter elements, to each of the finite element applications using their programming interface. These elements are inserted at the interfaces between the different sub-domains of the complete system modeled by each finite element analysis software package. Exchange of data between the coupled FEA codes is accomplished in a modular and synchronized manner using OpenFresco (Open-source Framework for Experimental Setup and Control). OpenFresco is an object-oriented, environment independent software framework initially developed for hybrid simulation in which certain aspects of a complete structure are simulated numerically and other aspects are simultaneously tested physically. An important practical advantage of this coupled analysis approach is that all of the connected FEA codes run concurrently and continuously, decreasing analysis time consumption by an order of magnitude or more compared to more traditional approaches that shut down and restart the coupled analysis codes at each integration time step. The implementation and accuracy of this approach to FE software coupling are demonstrated using dynamic analyses of three simple structural models from the field of earthquake engineering.
The Impact of International Financial Reporting Standards (IFRS) on Accounting Quality in Malaysia

There are two objectives of this study, first,it is to examine and compare the accounting quality in pre-and post-implementations IFRS from the viewpoint of investors. Second ,is to identify the differences in the accounting quality between the shariah compliant and non-shariah compliant companies in pre-and post-implementations of IFRS. Using 2169 firm-year observations from firms listed on the Bursa Kuala Lumpur Stock Exchange over the period of 2008 to 2016, the result shows that the implementation of MFRS have reduced the firms’ earnings management. However, this study provides new arguments that Shariah-complaints firms in Malaysia do not necessary have greater incentives to report high-quality reporting based on the investor perspectives. Our evidence thus help to explains the different impact on IFRS adoption on accounting quality in Malaysia and shariah complaint compnaies.
Development of numerical model for green water loading by coupling the mesh based flow models with the meshless models

The interaction between a moving vessel and incident waves leads to large relative motions and strong nonlinearities. This can result in violent water dynamics so that water flows onto the deck of the vessel, known as green water, and reaches crucial equipment and other deck structures. Green water events are considered as serious threat to the stability and operability of vessels, which should be reliably predicted and properly assessed in the design stage. Due to complexity of the problem, classification rules are limited in predicting the loads during the green water event. This thesis describes a novel method that is developed for simulating incompressible flows for the purpose of predicting green water events. The method is: meshless, Lagrangian, volume–conservative, second–order accurate in space, efficient, and suitable for coupling. The foundation of the method is a set of novel spatial operators based on the weighted–least squares, which are used to describe and solve the Navier–Stokes equations in strong form. Volume–conservative Lagrangian advection is used, which naturally handles violent free–surface flows. Boundary conditions are conforming to moving geometry at each time step. This makes coupling with other mesh–based and structural solvers straightforward. A completely parallel and efficient implementation of the methodology is described, which is validated by simulating cavity–flow, slamming, dam–breaking and sloshing experiments. The methodology is also validated by simulating both isolated and periodic green water events simulated in a domain–decomposed environment. The computed kinematics and dynamics of the flows compare well with experimental data and results obtained by other numerical methods.
Attenuation of diabetic disorders in experimentally induced diabetic rat by methanol extract of seed of Holarrhena antidysenterica.

The study was undertaken to evaluate the therapeutic efficacy of methanol extract of seed of Holarrhena antidysenterica in streptozotocin (STZ) induced diabetic rats. Extract was administered orally at a dose of 400 mg / kg body weight / day for 21 days, to STZ-induced diabetic rats. The fasting blood glucose level was decreased significantly after the treatment of methanolic extract to diabetic rats. Activities of hexokinase and glucose-6-phosphate dehydrogenase in liver as well as glycogen levels in liver and skeletal muscle all were increased significantly in extract treated diabetic group in compare with untreated diabetic control group. Activities of hepatic glucose-6-phosphatase were recovered significantly in extract treated diabetic group in respect to untreated diabetic group. To assess the antihyperlipidemic activities of this extract, we have also measured the serum levels of total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDLc), very low density lipoprotein cholesterol (VLDLc) and high density lipoprotein cholesterol (HDLc). The said extract also resulted a significant recovery in above mentioned biomarkers of lipid profile when treated to STZ-induced diabetic rat. Resettlement of all these parameters after the treatment of methanol extract of seed of H. antidysenterica is promising which has been reflected here from the comparison with the antidiabetic drug i.e. glibenclamide. After the monitoring of GOT and GPT activities in serum, it has been noted that the extract significantly correct the activities of these enzymes in STZ-induced diabetic rat. The result of this experiment demonstrated that the extracts of the said plant part possess a promising antidiabetic efficacy.
Effect Of Silicon On Corrosion Behaviour Of Al-Zn As A Low Voltage Sacrificial Anode For Marine Environment

A sacrificial anode is a method for material protection in the sea and coastal area. This method is widely applied in marine, subsea and ship structure. Al-Zn-In, a commercial grade of the sacrificial anode had a weakness in the possibility of stress corrosion cracking due to overprotection. This study tried to substitute indium with silicon as the alloying element with composition 0.5% and 1% wt. However, commercial grade Al ingot contained trace elements such as iron in the significant amount, which could make a β-Al9Fe2Si2 as an iron-rich intermetallic phase. Therefore, this study will also examine the effect of β-Al9Fe2Si2 on alloys corrosion behavior. The alloy was produced through casting process with resistance furnace. Corrosion behavior was characterized by cyclic polarization in 3.5% NaCl solution. Microstructure characterization was performed using Scanning Electron Microscope, Energy Dispersive Spectroscopy, and optical metallography. The result showed that the silicon increases the corrosion rate of Aluminum Zinc (Al-Zn) and reduced the potential protection of the alloy in high strength steel. Our research showed the corrosion took place along the interdendritic area where the β-Al9Fe2Si2 intermetallic phase formed in a micro galvanic manner
Financial Advisors, Financial Literacy, Payday Lending, and Bankruptcy

As the biblical definition of usury changed and cultural norms associated with incurring personal debt evolved, more financial options developed to meet increased demand. American consumer culture has evolved to promote a liberal use of credit. In particular, sub-prime debt instruments, such as payday lending, have been scrutinized because of excessive borrowing rates. We use state-level macroeconomic data and analyze the effect financial advisors have on payday lending regulation, maximum finance charges, and payday lending usage rates. Our results show payday lending is more heavily regulated, and maximum finance charges and payday lending usage rates are lower in states with a higher per-capita number of financial advisors. These findings suggest financial advisors are an important channel for improving financial literacy in their communities.
SOBRIETY TESTING: INTOXILYZERS AND LISTERINE ANTISEPTIC

The procedure and results are described of a study of the potential of mouthwash products (which contain alcohol) to interfere with breath alcohol detection units. The effect of Listerine Antiseptic on the CMI Intoxilyzer was measured for seven volunteers. Ratings on Intoxilyzer were made initially, and at one-, three, five-, and ten-minute intervals after completion of rinsing with Listerine Antiseptic. It was found that the highest level of alcohol was present at the one-minute rating period. A decreased though significant level of alcohol was present five minutes after rinsing with the Antiseptic. No significant level of alcohol was present at the final rating period conducted 10 minutes after the rinsing. Thus Listerine Antiseptic, containing 26.9% alcohol, has no effect of Intoxilyzer ratings following a 10-minute observation period.