Miracle-dz/UniFAR-FTUs huggingface dataset:
Molecular Basis of Herbicide Resistance in Amaranthus hybridus

Resistance of different species of weeds to s-triazines, a commonly used class of herbicides, has been shown to involve a change in the binding affinity of the herbicide to a chloroplast polypeptide of 32,000 daltons. A single amino acid difference in this 32,000-dalton protein appears to be responsible for resistance to the herbicide in Amaranthus hybridus.
An animal model for open femur fracture and osteomyelitis: Part I

Infection is an everyday problem in orthopaedics and is quite common in open fracture management. To study this process and provide a basis to prevent infection, we developed a model that includes trauma (blunt fracture in the fashion of Bonnarens and Einhorn), surgical stabilization (standardized intramedullary K‐wire fixation), and infection (Staphylococcus aureus inoculum). In this two‐part study, we found that 102 colony‐forming units of inoculum produced an optimal infection rate of 90–100%, which substantially challenged the immune system without overwhelming sepsis. We hypothesized that, in traumatic fractures, there is a specific immunological response that may lead to an increased rate of infection. In Part 2, we demonstrated immunosuppression (decreased Interleukin‐12 levels) at days 6, 10, and 12 after fracture fixation versus nonfractured control groups (p < 0.05). This study describes a rat model of femur factures with osteomyelitis that allows investigation of posttraumatic immunosuppression. © 2009 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 28:38–42, 2010
Optical characterization of nanoparticles and aggregates : light extinction spectrometry

A method to produce aerosols of nano silica aggregates has been developed to assess the capabilities of the light extinction spectrometry (LES) for characterizing the size distribution and the concentration of complex particles systems. The aggregates produced have a high fractal dimension and a regular cauliflower-like shape. LES on-line and real-time measurements are in rather good agreement with analyses performed with scanning electron microscope (SEM) onto collected samples. However, statistics obtained with SEM are not enough to definitively conclude on LES capabilities which are promising.
A Study on Oxygen Consumption in a Freshwater Fish Cyprinus carpio Exposed to Lethal and Sublethal Concentrations of Cypermethrin (25%Ec)

Any alteration in fish physiology indicates the deterioration of water quality parameters, since fish are one of the biological indicators of water quality. The recent development of biomarkers based on the study of the response of organisms to toxic chemicals has provided essential tools for the implementation of environment contamination monitoring programmes (Korami et al., 2000). Toxicants in the environment mainly enter into fish by means of their respiratory system. Respiratory activity of a fish is often the first physiological response to be affected by the presence of toxic pollutants in the aquatic media. These responses were found to be less sensitive, but could be used successfully in environmental monitoring. A change in respiration rate is one of the common physiological responses to toxicants and is easily detectable through changes in oxygen consumption rate, which is frequently used to evaluate the changes in metabolism under environmental deterioration.
Effect of BA and 2 iP on Shoot Proliferation and Somaclonal Variation of Gardenia jasminoides Ellis in vitro Culture

Shoot tips of Gardenia jasminoides Ellis were successfully propagated in B5 agar medium with BA (0, 2.5, 5, 7.5 and 10 mg.l) and 2iP (0, 2.5, 5, 7.5 and 10 mg.l) concentrations. The number of shoots in medium with 10 mg.l BA was 7 times greater than those in medium without BA. The BA induced plantlets had 100% survival rate and normal growth rate ex-vitro. The number of shoots in medium with 7.5 mg.l 2iP was 4 times greater than in 2iP free medium. All explants receiving 2iP gave chimeric plants showing different degrees of white leaf tissue. This is the first report of somaclonal variation induced by 2iP in G. jasminoides. Chimeric plants had 70% survival rate and showed slow growth ex-vitro. Abbreviations: BA 6-Benzylaminopurine, 2iP 6-(γ,γ-dimethylallyamino) purine, B5 B5 medium, MS Murashige and Skoog medium
Diversification in evolutionary arenas – assessment and 1 synthesis 2 3

3 Nicolai M. Nürk*1, H. Peter Linder*2, Renske E. Onstein3, Matthew J. Larcombe4, Colin E. Hughes2, 4 Laura Piñeiro Fernández2,5, Philipp M. Schlüter5, Luis M. Valente6, Carl Beierkuhnlein7, Vanessa 5 Cutts8, Michael J. Donoghue9, Erika J. Edwards9, Richard Field8, Suzette G.A. Flantua10, Steven I. 6 Higgins11, Anke Jentsch12, Sigrid Liede-Schumann1, Michael D. Pirie13,14 7 8 1 Department of Plant Systematics, Bayreuth Center of Ecology and Environmental Research (BayCEER), University of 9 Bayreuth, Universitätsstraße. 30, 95447 Bayreuth, Germany. nuerk@uni-bayreuth.de, orcid.org/0000-0002-0471-644X; 10 sigrid.liede@uni-bayreuth.de, orcid.org/0000-0003-2707-0335. 11 2 Department of Systematic & Evolutionary Botany, University of Zurich, Zollikerstrasse 107, 8008 Zurich, Switzerland. 12 peter.linder@systbot.uzh. ch, orcid.org/0000-0002-1373-2708; colin.hughes@systbot.uzh. ch, orcid.org/0000-0002-970113 0699; laura.pineiro@systbot.uzh. ch, orcid.org/0000-0002-8617-6490. 14 3 German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig, Deutscher Platz 5e, 04103 Leipzig, Germany. 15 onsteinre@gmail.com, orcid.org/0000-0002-2295-3510. 16 4 Department of Botany, University of Otago, PO Box 56, Dunedin New Zealand 9054. matt.larcombe@otago.ac. nz, 17 orcid.org/0000-0003-1632-9591. 18 5 Institute of Botany, University of Hohenheim, Garbenstraße 30, 70599 Stuttgart, Germany. philipp.schlueter@uni19 hohenheim.de, orcid.org/0000-0002-6057-0908. 20 6 Museum für Naturkunde, Leibniz Institute for Evolution and Biodiversity Science, Invalidenstraße 43, 10115 Berlin, 21 Germany. luis.valente@mfn.berlin, orcid.org/0000-0003-4247-8785. 22 7 Department of Biogeography, Bayreuth Center of Ecology and Environmental Research (BayCEER), University of Bayreuth, 23 Universitätsstraße. 30, 95440 Bayreuth, Germany. carl.beierkuhnlein@uni-bayreuth.de. 24 8 School of Geography, University of Nottingham, Nottingham, NG7 2RD, United Kingdom. 25 vanessa.cutts@nottingham.ac. uk, orcid.org/0000-0002-4986-2934. richard.field@nottingham.ac. uk, orcid.org/0000-000326 2613-2688 27 9 Department of Ecology and Evolutionary Biology, Yale University, PO Box 208105, New Haven CT 06511. 28 michael.donoghue@yale.edu; erika.edwards@yale.edu. 29 10 Department of Biological Sciences, University of Bergen, PO Box 7803, 5020, Bergen, Norway. s.g. a.flantua@gmail.com, 30 orcid.org/0000-0001-6526-3037. 31 11 Plant Ecology, University of Bayreuth, Universitätsstraße 30, 95447 Bayreuth, Germany. steven.higgins@uni-bayreuth.de, 32 orcid.org/ 0000-0001-5695-9665. 33 12 Department of Disturbance Ecology, Bayreuth Center of Ecology and Environmental Research (BayCEER), University of 34 Bayreuth, Universitätsstraße. 30, 95440 Bayreuth, Germany. anke.jentsch@uni-bayreuth.de, orcid.org/0000-0002-234535 8300. 36 13 Johannes Gutenberg-Universität, Mainz, 55099 Mainz, Germany. pirie@uni-mainz.de, orcid.org/0000-0003-0403-4470. 37 14 University Museum, University of Bergen, Postboks 7800, N-5020 Bergen, Norway. 38 39
Conceptions of Faith-Learning Integration

The integration of faith and learning (IFL) is the foundation upon which faithbased higher education has been built. As such, it imperative that educators at faith-based colleges and universities understand and implement this integration effectively. The purpose of this study was to determine how academic and student affairs educators conceptualize and practice the integration of faith and learning. The study also sought to identify key similarities and differences that exist between academic and student affairs educators regarding the integration of faith and learning. To answer these questions, a sample of nine academic educators and four student affairs educators were interviewed in order to discuss their thoughts and experiences regarding faith-learning integration. This study on faith-learning integration produced the following themes: (1) participants broadly understood IFL in cognitive, “worldview” terms, yet they also felt a close personal connection between their faith and learning; (2) participants developed their ability to integrate faith and learning primarily through mentor relationships with more experienced educators and secondarily through participants’ education and personal effort; (3) participants were motivated to integrate faith and learning by student learning and their own personal growth as educators; and (4) participants practice IFL through meaningful student interaction and fostering critical thinking. The findings of the study highlight the need for further discussion on the construct of faith-learning integration, as well as an increased focus on faculty development in this area.
Beta-lactam plus a Macrolide versus a Fluoroquinolone for Empiric Therapy of Hospitalized Patients with Community-Acquired Pneumonia: Results from the University of Louisville Pneumonia Study

Background: Current guidelines recommend a β-lactam plus a macrolide or fluoroquinolone monotherapy as the initial empiric antibiotic therapy for treatment of patients hospitalized with community-acquired pneumonia (CAP). Multiple studies have shown different results comparing the two regimens for the treatment of CAP. Our objective, in a city-wide prospective study, was to compare outcomes among hospitalized patients with CAP who received empiric treatment either with a β-lactam plus a macrolide or fluoroquinolone monotherapy. Methods: This was a propensity score matched case-control study. It was a prospective populationbased cohort study of all hospitalized adults with CAP. Patients were divided into two groups and propensity score matched based on empiric therapy; a β-lactam plus a macrolide compared to fluoroquinolone monotherapy. Study outcomes included time to clinical stability, length of stay, and inhospital, 30-day and 1-year mortality. Stratified Cox proportional hazards regression was performed to analyze continuous variable differences between groups, and conditional logistic regression was performed to analyze dichotomous variable differences in mortality. Results: An association was not found between the two groups for time to clinical stability (aHR: 1.06; 95% CI: 0.93-1.22), length of stay (aHR: 1.14; 95% CI: 0.99-1.32) or mortality. Conclusions: The present study failed to demonstrate differences in short or long-term outcomes for hospitalized CAP patients treated with either a β-lactam plus a macrolide or fluoroquinolone monotherapy. Therefore, our study does not support the superiority of one treatment over another. DOI: 10.18297/jri/vol3/iss1/6 Received Date: November 20, 2018 Accepted Date: January 14, 2019 https://ir.library. louisville.edu/jri/vol3/iss1/ Affiliations: 1Division of Infectious Diseases, School of Medicine, University of Louisville This original article is brought to you for free and open access by ThinkIR: The University of Louisville’s Institutional Repository. It has been accepted for inclusion in The University of Louisville Journal of Respiratory Infections by an authorized editor of ThinkIR. For more information, please contact thinkir@louisville. edu Recommended Citation: Salunkhe, Vidyulata; Furmanek, Stephen P.; and Arnold, Forest W. (2019) “Beta-lactam plus Macrolide vs Fluoroquinolone for Empiric Therapy of Hospitalized Patients with CAP: Results from the University of Louisville Pneumonia Study,” The University of Louisville Journal of Respiratory Infections: Vol. 3 : Iss. 1, Article 6. Objective This study sought to define whether clinical outcomes were similar or different for hospitalized patients with CAP based on the use of a β-lactam plus a macrolide versus fluoroquinolone monotherapy.
On the performance evaluation of ISI channels

The performance of finite intersymbol interference (ISI) channels in the presence of additive white Gaussian noise is evaluated by interpreting the ISI channel as a trellis code. Closed form results are obtained for ISI channels with one and two symbols of interference. An efficient algorithm is also introduced to evaluate the minimum free Euclidean distance of any ISI channel. >
Optimization of mycelial growth and mycochemical screening of Lentinus sajor-caju (fr.) from Banaue, Ifugao Province, Philippines

Lentinus sajor-caju (fr.). locally known as “ulat” in the Ifugao province, is one of the wild mushrooms used as food by the indigenous communities here. In this study, the optimal conditions for the mycelial growth of L. sajor-caju was studied to develop a protocol for its mass cultivation. Initially, L. sajor-caju was collected from a forest site in Banaue, Ifugao, Northern Philippines. Mycelial growth on different indigenous culture media and culture conditions, i.e. pH, aeration, illumination, and temperature were evaluated. Results showed highest secondary mycelial growth on coconut water gelatin (CWG) medium after 5 days of incubation. Secondary mycelia also grew best at pH 5, at room temperature (28-33°C), and in lighted and sealed or unsealed incubation conditions. The study also identified the chemical components and antioxidant activity of L. sajor-caju. Mycochemicals were extracted from dried mycelial mat with hot water. Results of the study showed the presence of terpenoids, glycosides, alkaloids, and saponins. Aqueous extracts of L. sajor-caju also contained a high amount of phenolics (75.29 mg/1g dried mycelial) but showed low radical scavenging activity (31.03%) as compared to the standard Catechin (97.41%).
Explaining The EU Regional Economic Growth upon Regional- and Country- Level Achievements in Education

This paper uses the methodological framework of multilevel mixed-effects models to shed light on the importance played by regional and country-level factors for the regional economic growth within the European Union (EU). In particular, factors in the area of education and Internet utilization are considered. Gradually, variance components models, random intercept models and random slope coefficient models are tested, and finally the random slope coefficient model is found to best fit our hierarchical dataset. The results indicate that at country level lower proportions of early school leavers, as well as higher expenditure on education and R&D, enhance regional growth. At regional level, higher achievements in education and higher rates of Internet usage are both associated with higher regional economic growth. The impact of education and Internet variables on the regional economic growth is generally found to be different across the New Member States and the Old Member States.
Response of three pomegranate cultivars ( Punica granatum L . ) to salinity stress 1

During 2009 and 2010 seasons, three pomegranate cultivars namely Manfalouty, Wonderfull and Nab – Elgamal were subjected to two levels of saline groundwater at concentration of 1.8 and 6.0 ds/m-1. The trees about seven years old grown at 2.5x3. 5 m apart in sandy clay loam soil under Sohag environmental conditions (upper Egypt). Results revealed that irrigation with saline water (6 ds/m-1), increased salt accumulation in leaves. On the other hand, higher significant reduction was observed in growth; flowering and yield with highly fruit cracking in relative to 1.8 ds/m-1. Total sugars and acidity percentages did not alter significant with varying of saline irrigation. The studied varieties (Manfalouty , Nab –Elgamal and Wonderfull) were affected differently by salt-stress in descending order as response to salinity. At the same time using saline irrigation water raised the salt accumulation in the root zone from 3.72 dS/m-1 to 4.8 and 7.7 and dS.m-1 under the lowest and highest saline ground water, respectively. These results were due to the excessive of highly accumulation of salts in the soil profile. Kew words: Pomegranate, salinity stress,yield, quality.
Epidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A Cells

CYP1A1 and CYP1A2 are transcriptionally activated in the human normal breast epithelial cell line MCF10A following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Shifting MCF10A cultures to medium deficient in serum and epidermal growth factor (EGF) caused rapid reductions in the activated (i.e., phosphorylated) forms of extracellular regulated kinases (ERKs) and the epidermal growth factor receptor (EGFR). Shifting to serum/EGF-deficient medium also enhanced TCDD-mediated induction of cytochrome P450 (CYP)1A1. Treatment of cells cultured in complete medium with the EGFR inhibitors gefitinib (Iressa), AG1478, and CI-1033 resulted in concentration-dependent reductions of active EGFR and ERKs, and increased CYP1A1 mRNA content ∼3- to 18-fold above basal level. EGFR inhibitors synergized with TCDD and resulted in transient CYP1A1 and CYP1A2 mRNA accumulations ∼8-fold greater (maximum at 5 hours) than that achieved with only TCDD. AG1478, gefitinib, and TCDD individually induced small increases (∼1.2- to 2.5-fold) in CYP1A1 protein content but did not cause additive or synergistic accumulations of CYP1A1 protein when used in combination. The mitogen-activated protein kinase kinase inhibitor PD184352 inhibited ERK and EGFR activation in a concentration-dependent fashion without causing CYP1A1 mRNA accumulation. However, cotreatment with PD184352 potentiated TCDD-mediated CYP1A1 induction. TCDD-mediated induction of CYP1A1 in MCF7-TETon-EGFR cells, a MCF7 variant in which EGFR expression can be controlled, was not affected by the activity status of EGFR or ERKs. Hence, EGFR signaling mutes both basal and ligand-induced expression of two aryl hydrocarbon receptor–responsive P450s in MCF10A cultures. However, these effects are cell context–dependent. Furthermore, CYP1A1 mRNA and protein abundance are not closely coupled in MCF10A cultures.
Effects of Vermicompost Levels on the Growth and Yield of HT 152 Tomato Variety Grown Organically

The aim of this study is to investigate the appropriate vermicompost dose in tomato production following organic direction. The tomato variety, HT152, was cultivated in field at the Center for Organic Agriculture Promotion and Studies (COAPS), Vietnam National University of Agriculture in autumn-winter season 2012 and 2013. Both experiments arranged in a Randomized Complete Block Design-RCBD included six vermicompost levels (10, 15, 20, 25, 30, 35 ton ha) with three replications.The results showed that vermicompost dose had significant effect on plant height, leaf number, and height and internode number from stump to the first flower cluster. When appling higher vermicompost levels, significant higher in individual fruit weight and yield of tomato were supported. The highest yield was obtained at 35 ton ha vermicompost (in autumn-winter season 2013) and at 30 ton ha vermicompost (in autumnwinter season 2012, but the difference was not significant as compared to level 35 ton ha). Vermicompost had beneficial effects not only on yield but also on fruit quality. By regression way, the regression equation that presents depended relation between yield of HT152 tomato variety and vermicompost dose was established as following: y = 0.0054x + 0.3596x + 34.602 with R2 = 0.4745. The result of optimal calculation indicated that the highest yield of HT152 tomato variety at optimal vermicompost dose of 33.3 ton ha. The knowledge gained from this study provided an important link about organic production, and could further improve product quality not only in tomato, but also in other plants.
Mapping magma prospectivity for Cordilleran volcanogenic massive sulphide ( VMS ) deposits using Nd-Hf isotopes : Preliminary results

Preliminary whole rock Nd-Hf isotopic data for porphyritic rhyolitic intrusive rocks from the Wolverine volcanogenic massive sulphide (VMS) deposit are presented herein. Pre-VMS (~352 Ma) quartz-feldspar porphyritic intrusive rocks (QFP) have Nb/Ta ratios (~12) and lower eNdt and eHft values, compared to syn-VMS (~347 Ma) feldspar porphyritic intrusive rocks (FP), which have higher Nb/Ta ratios (~17) and lower eNdt and eHft. Both suites have Proterozoic to Archean depleted mantle model ages indicative of crustal inheritance; however, the FP suite has a more juvenile signature. The progression from the crustal-dominated QFP suite, to a more basalt-influenced FP suite reflects the progressive opening of the Wolverine back-arc rift where early QFP magma was dominated by continental crustal melting, whereas the FP magma reflects greater back-arc basin extension, upwelling of basaltic magma beneath the rift, and enhanced continental crust-juvenile basalt mixing. Basalt upwelling beneath the Wolverine basin likely created the elevated geothermal gradient required for Wolverine VMS deposit formation.
Recent advances in ultra wideband communications systems

The last compilation of ultra wideband (UWB) communications systems is nearly two years old (see Fontana, R.J., Ultra-Wideband, Short-Pulse Electromagnetics, EuroEM 2000). This paper is intended as an update and illustrates recent trends in UWB communications for multi-user networking applications. More specifically, the paper describes three recent system developments: an ad hoc wireless UWB communications network for tactical voice and high-speed data communications; a long range UWB system for over-the-water and non line-of-sight voice, data and video communications; a wireless UWB communications network for support of both tactical and strategic (long haul) communications.
Predictors of Cognition in Adults With HIV: Implications for Nursing Practice and Research

The objective of this study was to identify predictors of cognitive performance among adults with HIV. Participants completed demographic, psychosocial, and mental and physical health questionnaires as well as cognitive measures of speed of processing, psychomotor ability and visuomotor coordination, attention and working memory, reasoning, and executive function. Hierarchical regression analyses were used to examine predictors of cognitive performance for each cognitive measure. Possible predictors included age, gender, socioeconomic status, Wide Range Achievement Test 3 Reading score (quality of education), social networks score, hardiness score, mood disturbance score, medical problems composite score, psychoactive drug use composite score, HIV chronicity, CD4+ lymphocyte cell count, and HIV medication usage. Model 1 examined demographic factors, and model 2 examined the contribution of the remaining variables on cognitive performance. Results revealed that several factors were predictive of cognitive functioning, with the individual regression models for each measure explaining 8% to 48% of the variability in performance. Overall, this study posits that among adults with HIV, the most consistent predictors of poorer cognition included older age, poorer reading ability, more depressed mood, CD4+ lymphocyte cell count less than 200, and lack of HIV medication usage. Results suggest that those aging with HIV are subject to decreases in cognitive functioning.