Miracle-dz/UniFAR-FTUs huggingface dataset:
Operative treatment of calcaneal fractures in elderly patients.

BACKGROUND Operative intervention is an accepted treatment for fractures of the calcaneus. However, the literature discourages surgery for these fractures in the elderly. The purpose of this paper was to review the outcomes of surgical treatment of displaced fractures of the calcaneus in elderly patients. METHODS Between November 1987 and June 2000, forty-two patients (forty-four fractures) who were sixty-five years of age or older underwent surgery for a calcaneal fracture. The mechanism of injury, fracture pattern, and medical comorbidities were recorded. Thirty-five patients with a total of thirty-seven fractures were available for follow-up, which was conducted with physical and radiographic examinations and outcomes assessment with the Short Form-36 (SF-36), the American Orthopaedic Foot and Ankle Society ankle-hindfoot scale, and the Short Musculoskeletal Function Assessment survey. RESULTS The minimum duration of follow-up was two years, and the average duration was forty-four months. All but one fracture (97% of the fractures) healed at an average of 110 days. The average active range of motion was 38 degrees of plantar flexion, 10 degrees of dorsiflexion, 16 degrees of inversion, and 11 degrees of eversion. The average American Orthopaedic Foot and Ankle Society score was 82.4 points, the average SF-36 score was 52.8 points, and the average Short Musculoskeletal Function Assessment score was 20.4 points. Posttraumatic subtalar arthritis developed in twelve patients. There were twelve minor complications and four major complications (three cases of osteomyelitis and one nonunion), all of which were treated successfully. CONCLUSIONS Open reduction appears to be an acceptable method of treatment for displaced calcaneal fractures in elderly patients. Careful patient selection is necessary because individuals presenting with severe osteopenia, those who are unable to walk or are able to walk only about the house, and those with a medical condition that precludes surgery may be better candidates for nonoperative care.
Immunohistochemical localization of delta‐ and mu‐opioid receptors in primate spinal cord

&NA; Immunofluorescent techniques were used to examine the distribution of &dgr;‐ and &mgr;‐opioid receptor‐like immunoreactivity (ir) in primate spinal cord. At every segmental level examined, opioid receptor‐ir formed a dense plexus of small profiles within the superficial dorsal horn. &dgr;‐Opioid receptor‐ir was found in laminae I and II, whereas &mgr;‐opioid receptor‐ir was confined mostly to lamina II. The distribution of opioid receptors within the superficial dorsal horn is appropriate for a localization to the central terminals of thinly myelinated and unmyelinated sensory neurons. Differences in the distribution of the &dgr;‐ and &mgr;‐opioid receptors may reflect the presence of these two opioid receptor types on different functional classes of afferent neurons, or they may relate to differences in presynaptic and postsynaptic localization within the spinal gray matter.
CEO AGE AND FIRM PERFORMANCE

Existing studies on horizon problem have investigated the short-term fluctuation of firm performance prior to the normal CEO retirement age of 65. Based on a sample of 1,940 CEOs in 1,390 industrial firms, we examine the change of firm performance over the entire CEO aging process. Empirical evidence shows that CEO age is negatively associated with firm growth and firm market value, and the sensitivity of these two relations diminishes along the CEO aging process. The association between age and firm profitability is conditional on firm size. In particular, we find a positive relation among younger CEOs in small firms and a negative relation among older CEOs in large firms. In this paper, we also examine the likelihood of CEO continuation beyond the regular retirement age of 65. Our empirical results show that stock ownership and firm growth increase the likelihood of delayed retirement past age 65, whereas firm-specific tenure and non-incentive compensation increase the likelihood of scheduled retirement at age 65. In addition, CEOs in small firms and CEOs recruited from outside are more likely to stay longer in their office.
Drivers of Firm's Value: Panel Data Evidence from Indian Manufacturing Industry

The purpose of this paper is to classify the value drivers into broad categories and then identify the major drivers of firm’s value for Indian manufacturing industry and also work out the sectorial sensitivity of value drivers. To achieve the objectives of the study we first derive the value driver’s model next we use panel regression with different model specifications to empirically analyse the major drivers of firm’s value. Our study reveals that sales, net margin, book value, dividend per share, beta and earnings per share are the six major financial drivers of value. All the strategic drivers when included in the model have significant relation with value without disturbing the r-square of the model. Thus, it is clear that apart from generic financial drivers, firms need to put more attention on strategic choices they make, because it is the strategic choice that will give firms an edge over others in developing economies like India. Further, we also observe sector specific priorities of the value drivers. This paper provides academicians and practitioners with an overview of the applicability of value drivers for Indian manufacturing industry. Further, the study will fill the gap in literature by adding value drivers’ evidence from one of the fastest growing economies in the world and will benefit researchers in arriving at common consensus for value drivers in emerging economies.
Effect of Mandatory IFRS Adoption on Accounting-Based Prediction Models for CDS Spreads

Abstract In this study, we examine the effects of mandatory IFRS adoption on accounting-based prediction models of CDS spreads for a sample of 292 firms in 16 countries. In our examination, we estimate the models for both financial and nonfinancial firms before and after mandatory IFRS adoption. We find that mean and median absolute percentage prediction errors are larger for both financial and non-financial firms after mandatory IFRS adoption. We also estimate accounting-based prediction models of CDS spreads separately for financial and non-financial US firms as a benchmark. Although US firms also show an increase in the mean and median absolute percentages of prediction errors over the same period, our findings from regressions that use a difference-in-difference design indicate that the increase is significantly greater for firms in countries that adopted IFRS mandatorily. We also find that in the post-adoption period, prediction errors are larger for firms in countries with weaker institutions such as low levels of property rights and more restrictive access to credit.
The Impact of Credit Constraints on Exporting Firms: Empirical Evidence from India

This paper studies the causal impact of credit constraints on exporting firms. We exploit a natural experiment provided by two policy changes in India, first in 1998 which made small scale firms eligible for subsidized direct credit, and a subsequent reversal in policy in 2000 wherein some of these firms lost their eligibility. Using firms that were not affected by these policy changes as our control group we find that expansion of subsidized credit increased the rate of growth of borrowing and export earnings by 20 percent in each case. Interestingly, the subsequent policy reversal in 2000 had no impact on the rate of growth of total borrowings and the export earnings.
Single-dose pharmacokinetics of the monobactam azthreonam (SQ 26,776) in healthy subjects

Azthreonam (SQ 26,776) is a new, completely synthetic, monocyclic beta-lactam antimicrobial agent that is highly active in vitro against most gram-negative bacteria. The pharmacokinetics of single intravenous doses of 125 to 4,000 mg, studied in 36 healthy male subjects, were best described by an open, linear, two-compartment kinetic model. The mean peak serum levels at 5 min after completion of 3-min infusions of 500-, 1,000- and 2,000-mg doses were 58, 125, and 242 micrograms/ml, respectively. The mean terminal serum half-life for all doses was 1.66 h, and the apparent volume of distribution was 0.18 liter/kg. The mean serum clearance was 1.27 ml min-1 kg-1, and urinary excretion averaged 68% of the doses administered. The pharmacokinetics of single intramuscular doses of 250 to 1,000 mg, studied in 18 subjects, were best described by a linear, one-compartment model, with first-order absorption and elimination. The mean peak serum levels occurring at 1 h after doses of 250, 500, and 1,000 mg were 12, 22, and 46 micrograms/ml, respectively. Other kinetic parameters were similar to those for intravenous administration. Tolerance of azthreonam was good, with only a mild rash in one subject and with mild to moderate transient elevations in serum transaminases and lactate dehydrogenase in two subjects.
Factors associated with departure from supported independent living programs for persons with serious mental illness.

OBJECTIVE Supported housing is a viable model that offers independence and opportunity for community integration. However, previous studies have shown that not all residents can sustain long-term tenancy. This study examined the extent to which personal and housing characteristics predicted positive and negative departures from independent housing programs that provided support services to persons with serious mental illness. METHODS The sample consisted of 237 persons participating in a supported independent living program in Philadelphia. Cox proportional hazards models were used to estimate the effects of personal and housing characteristics on the probability of positive departure (to an arrangement with more autonomy) and negative departure (to an arrangement with more supervision or to homelessness). RESULTS Most participants (69%) maintained continuous residence in the program for the study period, 14% experienced a positive departure, and 17% a negative departure. A self-reported past substance abuse problem increased the probability of a negative departure, and a more supportive relationship with program staff decreased the probability. A higher income increased the probability of a positive departure, whereas a higher level of social distress in the neighborhood decreased the probability. CONCLUSIONS The findings suggest that long-term housing tenure was not uncommon among supported independent living residents, but some were not able to maintain independent living and were discharged to shelters, institutions, or residential settings with more supervision. Predictors of positive and negative departure identified in this study may help service providers design services to meet the various needs of persons with serious mental illness for stable independent living.
Nosocomial Legionella pneumophila serogroup 5 outbreak associated with persistent colonization of a hospital water system

An outbreak of infections caused by Legionella pneumophila serogroup 5 was detected in a university hospital, and nosocomial reservoirs of the legionella epidemic were examined. Clinical isolates from two patients who had been affected by the L. pneumophila serogroup 5 outbreak, and from another patient with a legionella infection caused by the same serogroup 3 years later, were compared to L. pneumophila serogroup 5 isolates from the hospital water supply by two molecular methods, amplified fragment length polymorphism (AFLP) analysis and random amplified polymorphic DNA analysis (RAPD). Genotyping confirmed the epidemiological linkage of the first two patients, and linked their infections with the hospital water supply. The third clinical strain, which was also linked to the hospital water, was very similar to the epidemic strain. Even though the water distribution system was sanitized (superheat and flush sanitation), the epidemic strain was shown to be persisting in the hospital water outlets several years after its initial discovery.
The Midterm Experience of Tapered Stent Grafts in the Endovascular Management of Iliac Artery Aneurysms With Unfavorable Anatomy

We report our experience and the midterm results of a modern technique for endovascular management of isolated iliac artery aneurysms (IAAs) with unfavorable neck anatomy, which involves the inversion of an iliac leg of a Zenith stent graft. Patients who underwent endovascular IAA repair from 2002 to 2010 were reviewed. A total of 12 patients, with a mean age of 77.6 years, underwent endovascular repair of 13 IAAs. Mean size of the aneurysms was 54.6 mm (range 34-133 mm). Mean proximal neck diameter was 18 mm (range 15-22 mm). In 7 patients, the length of the proximal neck was <15 mm (10-14 mm). Only 1 patient developed thrombosis of the stent graft immediately after the operation. Patients were followed up for a mean of 31.5 months (range 18-72 months). Our midterm results demonstrate the durability of this technique in the management of iliac aneurysms with unfavorable anatomy.
The roles of xinyong and guanxi in Chinese relationship marketing

Purpose – This study incorporates two Chinese cultural variables guanxi (personal relationship) and xinyong (personal trust) with other relational variables that are well defined in the west, i.e. supplier competence, commitment, conflict handling and satisfaction to see how they generate partnership relationship in a sino‐western relationship marketing context.Design/methodology/approach – Research objectives are achieved through a combination of model building, quantitative design, testing of hypotheses using AMOS and analysis of findings. The subject scope is imbedded within cultural impact on relationship marketing in a sino‐western context.Findings – This study finds that Western suppliers must be competent in product knowledge, market development, and adaptation to buyers' requirements to resolve conflicts in order to establish their xinyong with the buyers. Competence allows suppliers to show psychological commitment and establish guanxi with the buyers. It also shows that guanxi has a stronger inf.
Spontaneous Trait Inference Is Culture-Specific

People with an independent model of the self may be expected to develop a spontaneous tendency to infer a personality trait from another person’s behavior, but those with an interdependent model of the self may not show such a tendency. We tested this prediction by assessing the cumulative effect of both trait activation and trait binding in a diagnostic task that required no trait inference. Participants first memorized pairings of facial photos with trait-implying behavior. In a subsequent lexical decision task, European Americans showed clear evidence of spontaneous trait inference: When they were primed with a previously studied face, lexical decision for the word for the implied trait associated with that face was facilitated, and the antonym of the implied trait elicited an electrophysiological sign associated with processing of semantically inconsistent information (i.e., the N400). As predicted, however, neither effect was observed for Asian Americans. The cultural difference was mediated by independent self-construal.
Exploring the Moderating Effect of Family CEO on the Association between Family Ownership and Firm Value: An Empirical Analysis of Top Indian Family Firms

We study 288 family firms included in the NSE CNX 500 index of the National Stock Exchange of India. We find an entrenchment-alignment-entrenchment relationship between family ownership and firm value. We show that family CEO has a negative moderating effect on the relationship between family ownership and firm value. When the interaction effect of Family CEO on family ownership is controlled, only family shareholding in the alignment range is found to be statistically significant. The study shows that family firms with family CEO suffer from a decrease in market valuation. This finding is extremely valuable given the fact that India is dominated by family firms and majority of family firms appoint a family member as CEO.
Sustainable supply chain management and inter-organizational resources: a literature review

On the basis of a content analysis, this paper explores the role of sustainable supply chain management as a catalyst of generating valuable inter-organizational resources and thus possible sustained inter-firm competitive advantage through collaboration on environmental and social issues. Drawing on the resource-based view and its extension, the relational view, this paper highlights that partner-focused supply management capabilities evolve to corporate core competences as competition shifts from an inter-firm to an inter-supply-chain level. The ‘collaborative paradigm’ in supply chain management regards strategic collaboration as a crucial source of competitive advantage. Collaboration is even more essential when supply chains aim at ensuring simultaneously economic, environmental and social performance on a product's total life-cycle basis. Inter-firm resources and capabilities emerging from supply-chain-wide collaboration are prone to become sources of sustained inter-firm competitive advantage, since they are socially complex, causally ambiguous and historically grown and hence particularly difficult to imitate by competitors. Copyright © 2009 John Wiley & Sons, Ltd and ERP Environment.
ANTECEDENT KEPUTUSAN PEMBELIAN ONLINE

The user internet in Indonesia have been increasing constantly each year. One of the internet user is for online purchasing. This online purchasing is not only caused by attractive user of its website but also affected by the special offer of products from this website. This study is to seek for antecedents of this online purchase decison. The data was collected by disseminating questionnaires via internet and face to face method. The respondents were internet users. The sampling method was purposive sampling. The model developed was two stage namely 1) attitude towards use is a function of trust and professionalism, and 2) online decision is a function of trust, professionalism and attitude towards use. The results show that all regression coefficients were significant. The independent variable that has the most influence toward the dependent ones is trust (X1) professionalism (X2) and attitude toward use (Y1) respecively. The t-test result show the entire of independent variables (trust, professionalism, and attitude toward use) have positive influence and significant toward the dependent variable that is the purchasing decision (Y2). The model showed a very good fit.it implies that all variables played impact includes in online purchasing.
Operational routines and supply chain competencies of Chinese logistics service providers

Purpose – Though resource based view (RBV) has been applied extensively in supply chain studies to examine how firms utilize logistics resources to attain superior performance, relatively little attention has been directed to exploring the effects of operational routines on logistics and supply chain (L&SC) competencies. The purpose of this paper is to examine the causal linkages between operational routines and L&SC competencies of Chinese logistics service providers (LSPs). Design/methodology/approach – A conceptual model on the relationships between operational routines and L&SC competencies was developed based on RBV. In total, 76 valid responses from a survey of Chinese LSPs provided the empirical data for the testing of the formulated hypotheses. Confirmatory factor analysis was used to develop the constructs for the model and hierarchical multiple regression analysis was performed to test the hypothesized relationships.Findings – Not all operational routines were drivers of L&SC competencies in the .
No evidence for a J-shaped curve in treated hypertensive patients with increased cardiovascular risk: The VALUE trial

Abstract Previous studies have debated the notion that low blood pressure (BP) during treatment, particularly diastolic (DBP), is associated with increased risk of cardiovascular disease. We evaluated the impact of low BP on cardiovascular outcomes in a high-risk population of 15,244 hypertensive patients, almost half of whom had a history of coronary artery disease (CAD). In the prospective Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial, patients were randomized to valsartan or amlodipine regimens and followed for 4.2 years (mean) with no difference in the primary cardiovascular endpoint. A Cox proportional hazards model was used to evaluate the relationship between average on-treatment BP and clinical outcomes. The relationship between BP and cardiovascular events was adjusted for age, gender and body mass index, and baseline qualifying risk factors and diseases (smoking, high total cholesterol, diabetes mellitus, proteinuria, CAD, previous stroke and left ventricular hypertrophy). DBP ≥ 90 mmHg, compared with < 90 mmHg, was associated with increased incidence of the primary cardiovascular endpoint (all cardiac events); however, DBP < 70 mmHg, compared with ≥ 70 mmHg, was not associated with increased incidence after covariate adjustment (no J-shaped curve). Similar results were observed for death, myocardial infarction (MI), heart failure and stroke, considered separately. Nadir for MI was at DBP of 76 mmHg and for stroke 60 mmHg. The ratio of MI to stroke increased with lower DBP. In CAD patients the MI to stroke ratio was more pronounced than in patients without CAD but there was no significant J-curve in either group. Systolic BP ≥ 150 but not < 130 mmHg, compared with 130–149 mmHg, similarly was associated with increased risk for primary outcome. In conclusion, patients in BP strata ≥ 150/90 mmHg, but not patients in BP strata < 130/70 mmHg, were at increased risk for adverse outcomes in this hypertensive, high-risk population. Although benefit in preventing MI in relation to preventing stroke levels off for the lowest BPs, these data provide no support for a J-curve in the treatment of high-risk hypertensive patients . The increase in the ratio of MI to stroke with lower DBP indicates target organ heterogeneity in that the optimal on-treatment DBP for cerebroprotection is below that for cardioprotection.
Interactive solving of vehicle routing and scheduling problems: basic concepts and qualification of tabu search approaches

This paper introduces a framework for the interactive solving of optimization problems and presents an interactive tabu search algorithm for the pick-up-and-delivery problem with time windows (PDPTW). The framework for the development of interactive algorithms is based on the idea of activating and deactivating constraints in the model of the problem under consideration. We start with an introduction to interactive problem solving and suggest an algorithmic framework. Next we focus on vehicle routing and scheduling applications. There we discuss the demand for interactive approaches, since established local search methods fail to produce reasonable solutions. Our idea is to support them by interactive manipulations. Therefore, we present a recent tabu search algorithm for the PDPTW We demonstrate several possibilities for human interactions by means of an additional tabu list.