Miracle-dz/UniFAR-FTUs huggingface dataset:
Immunohistochemical Localization And Monoclonal Antibodies Quantitative Measurement Of Carcinoembryonic Antigen (CEA) In Cervical Neoplasia

Objective: To evaluate the significance of including CEA in serum and tissues in the management protocol of patients with cervical malignancies. Methods: The study included 68 patients divided into three groups :Group A:20 patients with malignant cervical tumors; Group B: 12 patients with benign cervical lesions, Group C: 36 women without any gynaecologic disorder. Serum level of CEA was measured prior to treatment and following therapy. Formalin fixed and paraffin embedded tissue blocks taken from 2 different sites were prepared. Immunohistochemical staining for CEA was performed. Results: The mean pre-treatment serum CEA values and the mean difference in serum levels were significantly higher in malignant cervical lesion. The mean pre-treatment serum CEA levels were significantly higher in positively stained lesions. The mean pre-treatment serum CEA levels was significantly higher in positively stained cases of squamous cell carcinomas The mean serum CEA Values before treatment were significantly higher in positively stained carcinomas in stage IIa (P 0.049). The mean difference between preand post-treatment serum CEA was significantly higher in positively stained carcinomas in stage IIa (P 0.01). the mean difference in serum CEA levels was significantly higher in stage IIb in comparison with stage I. In conclusion: immunohistochemical identification of CEA in tumor tissue and monoclonal antibodies quantitative measurement of CEA in human serum may be a useful adjunct in the management protocol of patients with cervical malignancies.
Discussing Retirement: Insights from a Qualitative Research Project

This paper describes a qualitative research project of thirty interviews with women in Western Australia and summarises the outcomes generated from subsequent data analysis. Three key areas of interest are discussed that add to the existing body of economic research on women’s savings. Firstly, the project’s conclusions emphasise women’s own definitions of savings, their perceptions about their skill in making financial decisions and their ideas about risk and seeking financial advice. Secondly, the project contributes to a greater appreciation of the links between women’s decision-making contexts, processes and outcomes and the ways these affect their future access to economic resources. Thirdly, the research method played an important role in identifying potentially relevant literatures that had not yet been applied to studies of women’s savings. It is concluded that relatively small programs of qualitative research can generate valuable insights into economic research agendas.
Selective production of red azaphilone pigments in a Monascus purpureus mppDEG deletion mutant

The Monascus azaphilone (MAz) pigment is a wellknown food colorant that has yellow, orange and red components. The structures of the yellow and orange MAz differ by two hydride reductions, with yellow MAz being the reduced form. Orange MAz can be non-enzymatically converted to red MAz in the presence of amine derivatives. It was previously demonstrated that mppE and mppG are involved in the biosynthesis of yellow and orange MAz, respectively. However, ΔmppE and ΔmppG knockout mutants maintained residual production of yellow and orange MAz, respectively. In this study, we deleted the region encompassing mppD, mppE and mppG in M. purpureus and compared the phenotype of the resulting mutant (ΔmppDEG) with that of an mppD knockout mutant (ΔmppD). It was previously reported that the ΔmppD strain retained the ability to produce MAz but at approximately 10% of the level observed in the wildtype strain. A chemical analysis demonstrated that the ΔmppDEG strain was still capable of producing both yellow and orange MAz, suggesting the presence of minor MAz route(s) not involving mppE or mppG. Unexpectedly, the ΔmppDEG strain was observed to accumulate fast-eluting pigments in a reverse phase high-performance liquid chromatography analysis. A LCMS analysis identified these pigments as ethanolamine derivatives of red MAz, which had been previously identified in an mppE knockout mutant that produces high amounts of orange MAz. Although the underlying mechanism is largely unknown, this study has yielded an M. purpureus strain that selectively accumulates red MAz.
TAXONOMY AND EVOLUTION IN REDPOLLS

Multivariate analyses were performed on four standard measurements (wing-chord, tail-length, bill-length and bill-depth) of over 1000 sexed Redpolls, including samples from all currently recognized taxa. Samples of flammea and exilipes, phenotypically defined by colour were separable biometrically, as were samples of rostrata and hornemanni. Dark Redpolls from Iceland were almost indistinguishable from rostrata, but their average biometry was different from the pale birds breeding on the same island. Furthermore, pale birds from Iceland are different from the allopatric pale taxa exilipes and hornemanni, though they are closer to exilipes. The pale phenotype from Iceland is the most distinct Redpoll on that island, and might deserve a new name; the name islandica should be restricted to the dark, rostrata-like birds. Current taxonomic arrangements of Redpolls in two polytypic species are rather poorly founded, because most similarities in morphological criteria may be the result of convergent evolution. Mainly based on zoogeographical argument, specific rank could be assigned to hornemanni, exilipes, rostrata, andflammea. National Fund for Scientific Research, Belgium, Prinses Lydialaan 65, B-3030 Heverlee.
Social Resources and Enterprise Success among Micro and Small Women Entrepreneurs in Uganda

The purpose of the study is to explore micro and small enterprise (MSE) women understanding of enterprise success, and how among other factors social resources are related to enterprise success. The paper explores what MSE women entrepreneurs perceive as success along with rationale for such perceptions. The paper tests four hypotheses, and uses SEM to elicit interesting findings. These are complemented by qualitative results to shed light into the relationship between social resources, entrepreneurial competence and enterprise success. The study combines both qualitative and quantitative methods to analyse data collected from MSE women entrepreneurs in Uganda, East Africa. The data were collected through face-to-face interviews and detailed discussions with the entrepreneurs. Findings indicate that MSE women entrepreneurs perceive enterprise success both in financial and non-financial terms. Entrepreneurial competence plays a mediating role between social resources and enterprise success. Social resources are negatively related to enterprise financial success but positively related to enterprise non-financial success. Keywords: social resources, women entrepreneurs, financial success, non-financial success, entrepreneurial competence, Uganda, resources, trust, emancipation, micro enterprise
Molecular characterization and expression analysis of chalcone synthase gene during flower development in tree peony ( Paeonia suffruticosa )

Chalcone synthase (CHS, EC: 2.3.1.74) is a key enzyme in the flavonoid and anthocyanin biosynthesis pathway. In order to investigate the role of CHS in tree peony flower coloration mechanism, we isolated and characterized the CHS gene from Paeonia suffruticosa cv. Yu Ji Yan Zhuang and analyzed its spatial and temporal expression patterns during floral development. The cDNA sequence of the CHS gene in P. suffruticosa (Ps-CHS 1, genbank accession no. GQ483511) was 1475 bp in full length containing an opening reading frame (ORF) of 1185 bp that encoded a 394 amino acid polypeptide. Bioinformatic analysis showed that, Ps-CHS1 possessed all the conserved active sites for the CHS function as well as the family signature. Sequence alignment and phylogenetic analysis revealed that Ps-CHS1 shared high homology with CHS from plants in Salicaceae, Malvaceae and Rosaceae. The homology-based structural modeling showed that Ps-CHS1 had the typical structure of CHS. Southern blot analysis indicated that CHS was encoded by a small multigene family in the genome of tree peony. Anthocyanidin content in full-opening flower petals accumulated to the highest level. Real-time polymerase chain reaction amplification (PCR) analysis indicated that, Ps-CHS 1 showed the highest transcript abundance in petals, moderate levels in sepals, low levels in leaves and stamens, and the lowest levels in carpels. Ps-CHS 1 was actively expressed during flower development and increased gradually until reached maximal expression when flower fully opened. These results indicated that PsCHS 1 was involved in the flower pigmentation of tree peony.
Direct Numerical Simulation of Gravitational Turbulent Mixing

This paper presents the results of direct (without empirical models) numerical simulation of turbulent mixing at the plane interface of two incompressible fluids (gases) with various densities moving with a constant acceleration. The first similar studies were carried by Anuchina at al. [1] using the particle-in-cell method in 2D approximation. Then this approach was used by the authors of this paper to simulate the shear mixing [2]. The turbulence in these computations was treated as the result of random perturbations initially applied to the interface of two flows. The numerical simulation used 2D EGAK code [3]. The computational results were compared with the corresponding results obtained with the variant of semiempirical turbulence theory with isotropic Reynolds tensor (model 1). In [4] similar computations were run to simulate the gravitational mixing. This paper continues the studies in [4], using the direct numerical simulation with 2D and 3D methods [5],[6]. The data interpretation uses the version of semi-empirical theory (model 2) accounting for the anisotropy of Reynolds tensor.
Effect of Cold Storage of Various Pomegranate Cultivars Fruit Juices on Health Promoting Compounds and Their Activities

In this study, the total anthocyanins, ascorbic acid and phenolic content in sixteen different pomegranate cultivars are reported as 2.6-11.6, 3.2-13.6 and 956.5-2450.3 mg/100 g, respectively. Total soluble solid content varied between 12.10-18.10Brix, whereas pH and % titratable acidity values were within the range of 2.87-4.65, and 0.27-3.39, respectively. Total sugar values were ranged 9.6-22.1 g/100g. The total antioxidant capacity of pomegranate cultivars were found to be 2.54-12.4 (ABTS), 5.5-36.2 (DPPH) and 3.9-26.7 (FRAP) µmol TE/g fw. A high correlation between total antioxidant capacity and total anthocyanins (r2= 0.94), ascorbic acid (r2=0.75) and phenolic content (r2=0.94) was observed. Moreover, total anthocyanin, ascorbic acid, total phenolic contents and the antioxidant capacity of four pomegranate cultivars were monitored at the refrigeration temperature for two months. It was shown that ascorbic acid concentrations of the samples significantly decreased during storage, while there was no degradation could be observed in total phenolic concentrations. The degradation of total anthocyanins of Mersin 23 and Mugla 1267 cultivars during storage resulted in a dramatic decrease in the total antioxidant capacity of these samples from 12.36 to 5.6 (µmol TE/g fw) and 9.9 to 5.3 (µmol TE/g fw), respectively. These results demonstrated that ascorbic acid, total anthocyanins and total phenolic compounds are the main contributors for initial total antioxidant capacity and the difference between the cultivars are significant. However, degradation of ascorbic acid was shown to have no significant effect on the total antioxidant capacity unlike the total anthocyanins and phenolic compounds.
Exploring Coping Factors amongst Men Who Were Sexually Abused in Childhood

Men who were sexually abused in childhood are overrepresented in mental health and other clinical populations. There is heterogeneity in outcomes for such men and a substantial number develop coping strategies that minimise negative consequences of abuse. However, little research has been undertaken with abused men to understand the nature of their coping. This paper reports on one arm of a major study of mental health outcomes for Australian men who are survivors of childhood sexual abuse and presents findings from thematic analysis of qualitative interviews with thirty-nine men, exploring how their coping mechanisms have developed and the nature of the advice for coping they would give to professionals or other survivors. The study found that coping strategies developed adaptively through the life course but clustered into two types: those that are concerned with forms of suppression and denial, which are associated with negative mental health outcomes, and those that involve reframing the abuse, which tend to be associated with more positive outcomes. Implications of the study for practice are consistent with the advice suggested by the men themselves, that they were helped by consistent relationships with others who could provide practical support and inspire hope.
Quantification of argyrophillic, argentaffin and insulin immunoreactive cells in the small intestine in the opossum Didelphis aurita (Wied-Neuwied, 1826) - doi: 10.4025/actascibiolsci.v33i4.8644

The objective of this study was to quantify argyrophillic, argentaffin and insulin immunoreactive endocrine cells in the different segments of the small intestine of Didelphis aurita and measure probable differences in the number of these cells between adult and post-pubertal animals. Biological material consisted of ten male and female opossums specimen, divided in two groups according to weigh. The utilized staining techniques were Grimelius, modified Masson- Fontana and direct immunoperoxidase. Results indicated a predominance of argyrophillic cells in the small intestine of opossums from class 1 and 2, with an average of 52.58 and 56.15 cells mm -2 , respectively; of which, the average number of total endocrine cells, argyrophillic and argentaffin cells decreased distally in the intestinal segments of opossums from classes 1 and 2. No significant difference was observed for the insulin immunoreactive cells between the intestinal segments of animals from class 2. A greater number of insulin immunoreactive cells was encountered in the jejunum and ileum of animals from class 2 when compared to the same segment in animals from class 1.
Simulation of solar‐cycle modulation of the Southern Annular Mode using a chemistry‐climate model

Using a coupled chemistry‐climate model, we simulated the structural modulation of the Southern Annular Mode (SAM) caused by the change in ultraviolet radiation (UV) associated with the 11‐year solar cycle. In an enhanced UV run, the SAM signal in late winter extended to the upper stratosphere and persisted until the following autumn. In a reduced UV run, the signal was mostly confined to the troposphere and disappeared very quickly during the following summer. This greater persistence in an enhanced UV run is connected to the formation of an ozone anomaly in the polar lower stratosphere, produced by the modulation of the Brewer‐Dobson circulation in late winter.
FORMING COMPACT MASSIVE GALAXIES

In this paper we study a key phase in the formation of massive galaxies: the transition of star-forming galaxies into massive (Mstars ∼ 1011M⊙), compact (re ∼ 1 kpc) quiescent galaxies, which takes place from z ∼ 3 to z ∼ 1.5. We use HST grism redshifts and extensive photometry in all five 3D-HST/CANDELS fields, more than doubling the area used previously for such studies, and combine these data with Keck MOSFIRE and NIRSPEC spectroscopy. We first confirm that a population of massive, compact, star-forming galaxies exists at z ≳ 2, using K-band spectroscopy of 25 of these objects at 2.0 < z < 2.5. They have a median [N ii]/Hα ratio of 0.6, are highly obscured with SFR(tot)/SFR(Hα) ∼10, and have a large range of observed line widths. We infer from the kinematics and spatial distribution of Hα that the galaxies have rotating disks of ionized gas that are a factor of ∼2 more extended than the stellar distribution. By combining measurements of individual galaxies, we find that the kinematics are consistent with a nearly Keplerian fall-off from Vrot ∼ 500 km s−1 at 1 kpc to Vrot ∼ 250 km s−1 at 7 kpc, and that the total mass out to this radius is dominated by the dense stellar component. Next, we study the size and mass evolution of the progenitors of compact massive galaxies. Even though individual galaxies may have had complex histories with periods of compaction and mergers, we show that the population of progenitors likely followed a simple inside-out growth track in the size–mass plane of Δ log r e ∼ 0.3 Δ log M stars . > This mode of growth gradually increases the stellar mass within a fixed physical radius, and galaxies quench when they reach a stellar density or velocity dispersion threshold. As shown in other studies, the mode of growth changes after quenching, as dry mergers take the galaxies on a relatively steep track in the size–mass plane.
Determination of the Bacteriocin-like Substances Produced By Enterococcus hirae Isolated from Traditional Egyptian Food (Koskos)

The isolated organisms are screened for their antimicrobial activities against different microbial indicators. These activities expressed in inhibition zones against all tested indicator organisms. PCR products used to assess the DNA similarities and multiple sequences showed 92% identity to Enterococcus hirae (accession no.HM584102). Further identification to species level, E. hirae was based on pigment and carbohydrate formation. The SDS-PAGE analysis was indicated that bacteriocin of E. hirae is a two peptides of approximately 42 and 52 kDa. No antimicrobial activity after treatment of the cells with NaCl at pH 2.0. The leakage of K+ ion increased as the concentration of bacteriocin increased. The bacteriocins had a negative effect on the respiration, where the amount of consumed oxygen decreased by increasing the bacteriocins. No toxic effect against Artemia salina larva was recorded. Complete inactivation of antimicrobial activity was observed with Proteinase K and trypsin, respectively, after incubation at 37oC. No antimicrobial activity was recorded at pH values from 5 to 10. On the other hand, high antimicrobial activity was obtained at pH 3. Heat treatment on bacteriocin showed stability whereas nonsignificant results at 70oC or 100oC after 15 minutes while complete loss after incubation at 70oC, 100oC and by autoclaving.
Physics and numerical simulation of single photon avalanche diodes

We present results of the numerical simulation of the transient behavior of shallow junction single photon avalanche diodes (SPAD's). We developed a bidimensional model for above breakdown simulations and show that the initially photogenerated charge density builds up locally by an avalanche multiplication process and then spreads over the entire detector area by a diffusion-assisted process. To model real geometries, we developed a simplified model based on the obtained results. The importance of the photon-assisted spreading mechanism is evaluated and compared with the diffusive one. The contribution of the photon-assisted mechanism is minor in these geometries. The model is compared with the experimental data on the avalanche leading edge and the timing resolution; the agreement is good. We conclude that the model can be considered to be a useful tool for the design of improved structures.
Magnetic equivalent circuit model of surface type fractional-slot permanent magnet synchronous generator

Design of permanent magnet synchronous machines becomes more of an issue for all systems lately. There are many parameters that have influence for machine design. Each parameter should have optimized and their effects on the system should be determined. Any desired pre-design have been done for machine design except a few paper and it only showed by of Finite element analysis (FEA). In this article, analytical method is used in permanent magnet synchronous machine design and the effects of geometric on the performance of machine are presented. Magnetic equivalent circuit (MEC) model is used as numeric method. It is observed that the proposed MEC model is pertinent to Speed PC-BDC model and FEA. Besides proposed MEC model provides to calculate performances of the machines which have the desirable slot/pole combinations correctly. Proposed model is applied on the recently increased fractional slot direct drive synchronous generators.
The Poverty Hypothesis and Intergenerational Transmission of Child Labor: Evidence from Ghana

This study seeks to find evidence to support the claim that Child labor in Ghana is mainly a poverty phenomenon and follows an inter-generational pattern. The two econometric approaches used show that poor households are more likely to send their children out to work. Furthermore, parents are more likely to send their children out to work if they were child laborers themselves. The study recommends that policy should focus on the reduction of poverty since it is a major determinant of child labor, this will automatically prevent the perpetuation of child labor into the next generation. Keywords : Poverty Hypothesis, Intergenerational Transmission, Child Labor, Univariate Logit Model, Bivariate Probit Model, Ghana
The mammals of Anzali Wetland, in the Southern Caspian Sea

Anzali Wetland as a listed habitat in Montreux Record, was investigated for the mammal fauna during Jan. 2015 - Jan. 2016. About 165 km of water bodies and 200 km around Anzali Wetland were patrolled, respectively. By applying different methods, such as direct observation, different signs recording, using different sampling traps, nets and camera traps, twenty mammal species were identified from 5 orders and 13 families. While Wild boar, Golden Jackal and Common otter were widely distributed, Common badger, Asiatic wildcat and Jungle cat were observed in some parts of this wetland. Six rodent species were recognized in different parts of the wetland. Among four identified bat species, Nathusius’s pipistrelle has been reported only from this region in Iran. The most commonly recorded bat species was the Soprano pipistrelle, a species hereto recorded only from two Iranian localities. Two recognized species from order Eulipotyphla; Caspian shrew and a mysterious mole are important due to their narrow geographical distribution range as well as their taxonomic situation. Although there was no quantitative or qualitative data from the past, our results show that the situation of many mammal species are not suitable, and some of them are being increasingly threatened.
Physicochemical and Sensory Properties of Restructured Jerky with Four Additives

This study was carried out to evaluate the effect on properties of restructured jerky by the addition volume of additives. The treatments were divided into glutinous rice flour, potato starch, soybean and acorn powder. Moisture content, water activity (aw), thiobarbituric acid reactive substances (TBARS), color, yield and sensory evaluation were performed. The moisture contents of four types of restructured jerkies were in the range of 8.92-12.47%, and were lower than that of the control (17.92%). Water activity tended to decreased with increasing addition of all treatments. The restructured jerkies containing glutinous rice flour, potato starch, soybean and acorn powder had lower TBARS than the control. The drying yield tended to increase with increasing amount of additives. In the sensory evaluation results, the highest overall acceptability was found in jerky containing glutinous rice flour, potato starch, and acorn powder when the addition was 9%, while that for soybean powder was determined to be 5%. These results suggest that 9% additions of glutinous rice flour, potato starch or acorn, or 5% soybean powder are optimal addition volumes for the preparation of restructured jerkies.