Miracle-dz/UniFAR-FTUs huggingface dataset:
Dietary behavior among African Americans: assessing cultural identity and health consciousness.

The present study utilized the African self-consciousness (ASC) construct as an index of African-American cultural identity, and explored its association . with health consciousness and dietary behavior. One hundred ninety-seven African-American adults residing in a Southeastern community participated in the study. Results demonstrated few, but significant, correlations between cultural identity and health consciousness. A similar relationship was observed between cultural identity and dietary behavior. Further, after statistically controlling for health consciousness, cultural identity contributed unique variance to dietary behavior. These findings represent preliminary evidence suggesting the general viability of cultural models in explaining African-American health behavior. More importantly, the study offers avenues for additional research on the complex roles played by culture and cultural identity in African-American dietary behavior.
Rectal Carcinoma, Recent Staging Strategy by MRI Using Diffusion Weighted Sequence

Objective: MRI is currently the imaging modality of choice for the detection, characterization, and staging of rectal cancer. A variety of examinations have been used for preoperative staging of rectal cancer, including digital rectal examination, endorectal (endoscopic) ultrasound, CT, and MRI. Endoscopic ultrasound is the imaging modality of choice for small and small superficial tumors. MRI is superior to CT for assessing invasion to adjacent organs and structures, especially low tumors that carry a high risk of recurrence. Background: Colorectal cancer (CRC) is the third most common cancer in both sexes combined worldwide, after prostate and breast cancer with an incidence of 40 in 100,000. Rectal carcinoma accounts for more than one-third of colorectal tumors and is associated with signiﬁcant morbidity and mortality. Currently, MRI using diffusion weighted sequence is the most sensitive and specific modality in staging rectal cancer as it is able to depict the mesorectal fascia and its relation to the tumor margins precisely. Methods: This study included 50 patients, (32 male and 18 female) previously diagnosed as cancer rectum based on proctoscope and histopathological biopsy. The age range of the patients was from 18 years to 78 years. All patients will be subjected to the following: detailed history, clinical examination, proctoscopic assessment and histopathological data. All patients underwent MRI of the pelvis specifically cancer rectum protocol. Results: The most frequently encountered clinical presentation among cancer rectum patients was bleeding per rectum (14), constipation (26), incidentally discovered liver metastasis (6) and intestinal obstruction (4). MRI evaluation of T staging in correlation to the histopathological examination showed sensitivity (80%), specificity (93%), accuracy (94%). Lymph node (LN) metastatic spread was evaluated by MRI and showed sensitivity (87%), specificity (92%), accuracy (92.6%), PPV (84.8%) and NPV (96.7%). Regarding circumferential resection margin (CRM) MRI assessment revealed; sensitivity (96%), specificity (94%), accuracy (96%), PPV (95%) and NPV (94.3%). Conclusions: MRI is an accurate and sensitive imaging method delineating tumoral margins, mesorectal fascia involvement, lymph nodes, and distant metastasis. MRI can accurately delineate the mesorectal fascia involvement, which is one of the main decision points in planning treatment.
havior factors , one related primarily to high levels of extraversion and another related to low agreeableness

Hierarchical personality models have the potential to identify common and specific components of DSM-IV personality disorders (PDs), and may offer a solution for the re-tooling of personality pathology in future versions of the DSM. In this paper, we examined the hierarchical structure of the Dimensional Assessment of Personality Pathology—Basic Questionnaire (DAPP-BQ; Livesley & Jackson, 2009) and the capacity of various trait components at different levels to predict DSM-IV PD symptoms. Participants were 275 psychiatric outpatients and 365 undergraduate students. Goldberg’s (2006) bass-ackwards method was used to investigate the hierarchical structure of the DAPP-BQ. The predictive capacity of hierarchy components was assessed. We found that Level 5 of the hierarchy enhanced the capacity of the DAPP-BQ for predicting DSM PD symptoms beyond a four-factor structure, particularly for borderline PD.
Locoregional Recurrence in Patients With Triple-Negative Breast Cancer: Preliminary Results of a Single Institution Study

Purpose: To examine the impact of radiotherapy on breast cancer patients with triple-negative (ER-, PR-, HER2/neu-) disease. Materials and Methods: A prospectively collected database of 152 triple negative breast cancer patients was initiated in 2004. A total of 77 patients who had all phases of their therapy (surgery, chemotherapy, and radiotherapy) at our institution with a minimum of 2-months follow-up are included. Patients with all types of surgery (lumpectomy or mastectomy), chemotherapy (neoadjuvant or adjuvant), and radiotherapy (tangents only or comprehensive nodal irradiation) are included. Patients received radiotherapy in the setting of breast-conservation and in the postmastectomy setting for ≥5 cm primary tumors and/or ≥4 positive lymph nodes. Patients were divided into 2 groups for statistical analysis, based on whether they received radiotherapy or not. Results: In the cohort, 53 (69%) received radiotherapy, 24 (31%) received no radiotherapy. The median follow-up was 23.2 months (range, 2.0–63.1). In the alive patients, the median follow-up time was 25.6 (range, 2.0–63.1) months. Patients who received radiotherapy were significantly more likely to be of a higher AJCC stage (P < 0.001) than patients who did not receive radiotherapy. Of the patients who received radiotherapy, 33 (61.1%) did so for breast conservation. For the entire group, 1- and 3-year overall survivals are 90.9% and 86.3%, respectively. The 3-year actuarial locoregional relapse-free survival probability for patients who received radiation was higher than those who did not receive radiation (79.6% vs. 57.9%, P = 0.049). Conclusions: Despite significantly lower AJCC stage, patients with triple-negative breast cancer who do not undergo radiotherapy have a significantly higher risk of locoregional recurrence.
The Impact of Internal Control Weaknesses on Firms’ Cash Policies

We study the association between firms' Section 302 and Section 404 internal control weaknesses and these firms' cash-to-cash flow sensitivities. We also examine whether the presence of the internal control weaknesses affects the relationship between firms' asset liquidity and stock liquidity. We find that the presence of Section 404 internal control weaknesses is associated with stronger cash-to-cash flow sensitivities and with weaker impact of higher asset liquidity on stock liquidity. Our results suggest that internal control weaknesses increase firms' reliance on internal, as opposed to external, financing. Also, internal control weaknesses increase uncertainty over future uses of cash, thereby reducing the positive impact of higher relative cash balances on stock liquidity. Thus, our study provides additional evidence on the potential costs of internal control weaknesses.
Scheduled Castes, Legitimacy and Local Governance: Continuing Social Exclusion in Panchayats

People of the Scheduled Castes have a long history of being discriminated against, exploited, and placed at the bottom of caste society. The panchayati raj, after the enactment of the 73rd Constitutional Amendment, brought in measures to overcome these past indignities, and provided a quota within ordinary seats and among the office bearers of the panchayats. There is, however, strong resistance among the higher castes (just above that of the Scheduled Castes in many cases), about reservation of the post of panchayat president for Scheduled Caste people. This paper looks at some of the consequences of having a quota for the Scheduled Castes for the post of president in the grama panchayats of Karnataka and Tamil Nadu, with the concept of legitimacy to consider the perceptions of the higher castes as well as the participation of the Scheduled Castes in panchayats.
Interaction of Decay-Accelerating Factor with Coxsackievirus B3

ABSTRACT Many entero-, parecho-, and rhinoviruses use immunoglobulin (Ig)-like receptors that bind into the viral canyon and are required to initiate viral uncoating during infection. However, some of these viruses use an alternative or additional receptor that binds outside the canyon. Both the coxsackievirus-adenovirus receptor (CAR), an Ig-like molecule that binds into the viral canyon, and decay-accelerating factor (DAF) have been identified as cellular receptors for coxsackievirus B3 (CVB3). A cryoelectron microscopy reconstruction of a variant of CVB3 complexed with DAF shows full occupancy of the DAF receptor in each of 60 binding sites. The DAF molecule bridges the canyon, blocking the CAR binding site and causing the two receptors to compete with one another. The binding site of DAF on CVB3 differs from the binding site of DAF on the surface of echoviruses, suggesting independent evolutionary processes.
Emerging treatment options for psoriasis

: The treatment of psoriasis has evolved over the years, with the recent focus largely on the use of biologics and anti-interleukin-17 agents. With treatment options expanding, practitioners and patients may find control of psoriasis more convenient and safer to achieve. In this article, we review the literature on emerging medications for the treatment of psoriasis. Although some of the new medications under development, such as the anti-interleukin-17 agents, are being shown to be very efficacious in the treatment of psoriasis in premarketing trials, more information regarding their long-term use is needed to demonstrate their superiority over available modalities.
1 Allosteric effects between the Antibody constant and 2 variable regions : A study of IgA Fc mutations on 3 antigen binding 4

Therapeutics antibodies have increasingly shifted the paradigm of disease treatments, 11 from small molecules to biologics, especially in cancer therapy. Despite the increasing number of 12 antibody candidates, much remains unknown about the antibody and how its various regions 13 interact. In fact, the constant region can govern effects that might be useful in reducing the 14 unwanted consequences resulted from systemic circulation. For this reason, apart from the 15 commonly used IgG isotypes, IgA antibodies are promising therapeutics drugs, given its localized 16 mucosal effects. While the antibody Fc effector cell activity has been well explored, recent research 17 has shown evidences that the constant region of the antibody can also influence antigen binding, 18 challenging the conventional idea of region-specific antibody functions. To further investigate this, 19 we analyzed the IgA antibody constant and its allosteric effects onto the antigen binding regions, 20 using recombinant Pertuzumab IgA1 and IgA2 variants. We found mutations in the C-region to 21 reduce Her2 binding, and our computational structural analysis showed that such allosteric 22 communications were highly dependent on the antibody hinge, providing the evidence to consider 23 antibodies as a whole protein rather than a sum of functional regions. 24
Endosperm sugar accumulation caused by mutation of PHS8/ISA1 leads to pre‐harvest sprouting in rice

Pre-harvest sprouting (PHS) is an unfavorable trait in cereal crops that could seriously decrease grain yield and quality. Although some PHS-associated quantitative trait loci or genes in cereals have been reported, the molecular mechanism underlying PHS remains largely elusive. Here, we characterized a rice mutant, phs8, which exhibits PHS phenotype accompanied by sugary endosperm. Map-based cloning revealed that PHS8 encodes a starch debranching enzyme named isoamylase1. Mutation in PHS8 resulted in the phytoglycogen breakdown and sugar accumulation in the endosperm. Intriguingly, with increase of sugar contents, decreased expression of OsABI3 and OsABI5 as well as reduced sensitivity to abscisic acid (ABA) were found in the phs8 mutant. Using rice suspension cell system, we confirmed that exogenous sugar is sufficient to suppress the expression of both OsABI3 and OsABI5. Furthermore, overexpression of OsABI3 or OsABI5 could partially rescue the PHS phenotype of phs8. Therefore, our study presents important evidence supporting that endosperm sugar not only acts as an essential energy source for seed germination but also determines seed dormancy and germination by affecting ABA signaling.
Knowledge and Attitude of Dental Health Professionals about Middle East Respiratory Syndrome in Saudi Arabia

Aim and Objective: This study aims to evaluate the knowledge and attitude of practicing dental health professionals (DHPs) (dentist and dental auxiliaries) toward Middle East Respiratory Syndrome coronavirus (MERS-CoV) in Saudi Arabia. Materials and Methods: A cross-sectional descriptive study was undertaken among practicing DHPs in Saudi Arabia. A total of 202 DHPs participated in this study. Knowledge and attitude were assessed using self-administered and pretested questionnaire. The questionnaire was administered online through Survey Monkey® program by sending link to the registered E-mail. Descriptive statistics were performed on demographic data. Mean knowledge and mean attitude scores of DHPs were calculated. Mann–Whitney U-test and Kruskal–Wallis tests were used to disclose the differences between study variables. Chi-square tests and Spearman's correlation tests were applied to find the associations between the variables. Results: The study participants showed mean knowledge score of 12.26 ± 2.27 (based on 17 knowledge questions) and attitude score of 8.63 ± 1.68 (based on 10 attitude questions). The spearman's test showed the positive correlation between knowledge and attitude of DHPs about MERS (r = 0.093, P = 0.188). Knowledge gaps were reflected in questions related to the duration of infectivity (47.5%), treatment of MERS (39.6%), reservoir of MERS-CoV (38.1%), availability of vaccination against MERS-CoV (25.2%), the likelihood of infection (24.3%), and the type of MERS-CoV (23.3%). DHPs showed a positive attitude toward adherence to universal precautions given by CDC and WHO (0.94 ± 0.25), active participation infection control program (0.94 ± 0.24), and use of gowns, gloves, mask, and goggles while dealing with MERS-CoV patients (0.97 ± 0.17). Male DHPs showed significantly higher knowledge and positive attitude toward MERS-CoV infection compared to females. Conclusion: DHPs participated in this study showed good knowledge and positive attitude toward MERS. However, still few lacunae in the knowledge and attitudes toward MERS-CoV were found requiring extensive educational programs.
SAMPLING CONSIDERATIONS FOR IMPROVING HOME RANGE ESTIMATES OF DESERT TORTOISES: EFFECTS OF ESTIMATOR, SAMPLING REGIME, AND SEX

Home range estimation as a measure of spatial utilization is an important tool in the management of wildlife. Operational methods of defining the spatial requirements of an animal differ in sampling regime and interpretation. The two most commonly used estimators, the minimum convex polygon (MCP) and the fixed kernel (FK), each provide a different measure of land use, yet, together allow for a better understanding of the spatial needs of a particular animal. Sampling frequency, the number of individuals, and other user-defined inputs differentially affect home range estimates using these two procedures. For the comparison of either MCP or FK estimates to be reliable, these variables need to be as similar as possible across studies. We conducted an intensive radio-telemetry study on a large number of Desert Tortoises (Gopherus agassizii) to determine an optimal sampling effort for home range estimation using both the MCP and FK estimates, and to identify factors important to space use by this species. Data were parsed into sampling regimes representative of previous home range studies in an effort to compare estimates across studies. Home range estimates using the MCP were over two times larger in this study when compared to previous studies on the Desert Tortoise in the Mojave Desert. Results indicated that an increased sampling frequency inflates MCP estimates, while providing more use-specific detail and decreasing area for FK estimates. Analyses demonstrated home range area to be greatly affected by choice of estimator (MCP or FK), sampling regime, and sex. We recommend an intensive and systematic sampling effort to better define home range estimates; as well as, to provide comparable data across studies for this and other species of herpetofauna. Both home range estimators provide valuable information on the biological needs of the Desert Tortoise and should be identified as a priority in land use investigations and conservation decisions for this species.
Making Sense of the “Wounded Healer” Phenomenon

The conceptualization of the “wounded healer” is so historic that its roots can be traced back to the mythological figures of ancient Greece. The construct has also been used to illustrate the capacity of a certain inner “woundedness” within individuals that affects (if not enhances) their abilities to heal others, even while attempting to heal themselves. Yet, confusion remains as to what a “wounded healer” is, or how the woundedness serves to help others. A review of this subject matter was undertaken by the first author, under the supervision of the second author, due to a personal interest in the topic, as well as in anticipation of a career in counselling psychology. The paper was written with the intention to demystify the concept of “wounded healing” with further consideration of its influence on the therapist-client relationship. After describing the mythology, vocation and wounded healer paradigm, the paper considers the empirical research on the wounded healer phenomenon ending with some reflections on wounded healing in psychotherapy, and suggestions for further research. Waitari Nā te tino tawhito o te hiranga whakaaro mō te kaiwhakaora taotū ka taea te whai i ōna pūtaketanga ake ki ngā whakaatanga pakiwaitara o Kiriki. Kua whakamahia anō hoki tēnei aria hai tauira i te whānui o te ētahi mamae tautahi whakaroto ā-ngākau ā, ka pawerahia tōna kaha ki te whakaora i ētahi atu ahakoa e whakatau ana ki te whakaora i a rātou anō. Ahakoa tērā, kai te huri haere tonu ngā whakaaro ki te tikanga o tēnei mea te “kaiwhakaora taotū” ki te mōhio rānei he aha tōna painga ki ētahi atu. I arotakehia tēnei kaupapa e te kaituhi tuatahi, i raro i te maru o te kaituhi tuarua nā tōna kaingākau tonu ki te kaupapa me te wawata ka tae hai kaimahi hinengaro. I āta tuhia tēnei korero ki te whakanoa i te aria o te whakaora taotū, ki te te aro atu anō hoki ki tōna pānga ki te whakawhanaungatanga o te kaihaumanu me te kiritaki. Kia mutu te whakamārama pakiwaitara, mahi me aria o te kaiwhakaora taotū, ka tahuri ngā whakaaro ki ngā rangahau kitea-ā-kanohi mō te wheako kaiwhakaora taotū, ka hoki whakamuri ai ki ngā whakaoranga ake i roto i tēnei mahi me te whakatau anō ai i ētahi atu rangahautanga. Jamieson, J., & Scherman, R. (2014). Making sense of the “wounded healer” phenomenom. Ata: Journal of Psychotherapy Aotearoa New Zealand, 18(1), 67-79. DOI: 10.9791/ajpanz.2014. 06 © New Zealand Association of Psychotherapists Inc.
Textual Analysis in Real Estate

This paper incorporates text data from MLS listings from Atlanta, GA into a hedonic pricing model. Text is found to decrease pricing error by more than 25%. Information from text is incorporated into a linear model using a tokenization approach. By doing so, the implicit prices for various words and phrases are estimated. The estimation focuses on simultaneous variable selection and estimation for linear models in the presence of a large number of variables. The LASSO procedure and variants are shown to outperform least-squares in out-of-sample testing.
The Hitchhiker’s Guide to Testing Statistical Significance in Natural Language Processing

Statistical significance testing is a standard statistical tool designed to ensure that experimental results are not coincidental. In this opinion/ theoretical paper we discuss the role of statistical significance testing in Natural Language Processing (NLP) research. We establish the fundamental concepts of significance testing and discuss the specific aspects of NLP tasks, experimental setups and evaluation measures that affect the choice of significance tests in NLP research. Based on this discussion we propose a simple practical protocol for statistical significance test selection in NLP setups and accompany this protocol with a brief survey of the most relevant tests. We then survey recent empirical papers published in ACL and TACL during 2017 and show that while our community assigns great value to experimental results, statistical significance testing is often ignored or misused. We conclude with a brief discussion of open issues that should be properly addressed so that this important tool can be applied. in NLP research in a statistically sound manner.
PUVA versus NB-UVB in Management of Vitiligo, Clinico-Immuno-Pathological Study

Background: Phototherapy is the most commonly used modality in the treatment of vitiligo. Oral PUVA is the classical treatment and the NB-UVB is a recently introduced form excluding the shorter erythemogenic wavelengths. Aims: This study was designed to compare the effects of PUVA and NB-UVB clinically and immuno-pathologically in managing non segmental vitiligo. Patients/Methods: Thirty vitiligo patients were divided randomly into two groups and treated either by oral PUVA or by narrow band UVB for 4 months, and evaluation was done clinically and immuno-pathologically. Results: One patient in PUVA group (3.3%) failed to respond to therapy while 29 patients (93.3%) improved including all NB-UVB cases. Excellent repigmentation was achieved in 6.7% in PUVA group and 66.6% in NB-UVB group; good repigmentation was achieved in 60% in PUVA and 20% in NB-UVB while 26.7% in PUVA and 13.3% in NB-UVB showed mild repigmentation. The color matching was excellent in all NB-UVB patients. Recurrence and activation of vitiligo were demonstrated in some NB-UVB cases and were less in PUVA treated cases. Microscopic examination revealed persistence of dermal lympho-histiocytic infiltrate and the interface changes in biopsies from vitiliginous lesions treated with NB-UVB more than with PUVA. Conclusions: NB-UVB provides significant better results than oral PUVA in managing non-segmental vitiligo. Although NB-UVB therapy gives a rapid effect, yet the observation of recurrences and development of new lesions of vitiligo were less significant with PUVA. It was also observed that PUVA has better immuno-modulatory effect on vitiligo than NB-UVB and may give better response on a longer period of time.
Food Demand Elasticities for Australia

type="main" xml:id="ajar12111-abs-0001"> There is renewed interest in robust estimates of food demand elasticities at a disaggregated level not only to analyse the impact of changing food preferences on the agricultural sector, but also to establish the likely impact of pricing incentives on households. Using data drawn from two national Household Expenditure Surveys covering the periods 1998/1999 and 2003/2004, and adopting an Almost Ideal Demand System approach that addresses the zero observations problem, this paper estimates a food demand system for 15 food categories for Australia. The categories cover the standard food items that Australian households demand routinely. Own-price, cross-price and expenditure elasticity estimates of the Marshallian and Hicksian types have been derived for all categories. The parameter estimates obtained in this study represent the first integrated set of food demand elasticities based on a highly disaggregated food demand system for Australia, and all accord with economic intuition.