Miracle-dz/UniFAR-FTUs huggingface dataset:
AN INTERACTIVE SEARCH ASSISTANT ARCHITECTURE BASED ON INTRINSIC QUERY STREAM CHARACTERISTICS

Search engine query log mining has evolved over time to more like data stream mining due to the endless and continuous sequence of queries known as query stream. In this paper, we propose an online frequent sequence discovery (OFSD) algorithm to extract frequent phrases from within query streams, based on a new frequency rate metric, which is suitable for query stream mining. OFSD is an online, single pass, and real‐time frequent sequence miner appropriate for data streams. The frequent phrases extracted by the OFSD algorithm are used to guide novice Web search engine users to complete their search queries more efficiently. YourEye, our online phrase recommender is then introduced. The advantages of YourEye compared with Google Suggest, a service powered by Google for phrase suggestion, is also described. Various characteristics of two specific Web search engine query logs are analyzed and then the query logs are used to evaluate YourEye. The experimental results confirm the significant benefit of monitoring frequent phrases within the queries instead of the whole queries because none‐separable items. The number of the monitored elements substantially decreases, which results in smaller memory consumption as well as better performance. Re‐ranking the retrieved pages based on past users clicks for each frequent phrase extracted by OFSD is also introduced. The preliminary results show the advantages of the proposed method compared to the similar work reported in Smyth et al.
A longitudinal study of the relationship between depressive symptoms and alcohol use in a sample of inner-city black youth.

OBJECTIVE The purpose of this study was to examine longitudinally the relationship between depressive symptoms and alcohol use in a sample of black youth. METHOD Participants were 458 black males and females interviewed annually during the high school years and then for 3 years during the transition to adulthood. The relationship was examined using growth curves with Hierarchical Linear Modeling. RESULTS The results suggest that depressive symptoms decrease over time, whereas the use of alcohol increases. The findings also suggest that youths use alcohol as a way to cope with depressive symptoms and that males are more likely to use alcohol as self-medication. The results also indicate that changes in alcohol use do not predict depressive symptoms, but that life changes associated with the transition to adulthood, such as attending college, predict changes in depressive symptoms and alcohol use. CONCLUSIONS Findings highlight the role of depressive symptoms for predicting alcohol use among black youth and the role of significant life transitions in altering the pattern of alcohol use presented previously by these youths.
Role of Tumor Necrosis Factor-α -308 G/A Promoter Polymorphism in Gastric Cancer

Background/Aim: Gastric cancer (GC) is the fourth most common cancer and the second most common cause of cancer death world-wide after lung cancer. It is a multifactorial disease with the involvement of both genetic and environmental risk factors. Genetic variation in genes encoding cytokines and their receptors, determine the intensity of the inflammatory response, which may contribute to individual differences in severity of outcome of the disease. Tumor necrosis factor alpha (TNF-α) is a potent pro-inflammatory cytokine and acid inhibitor. A bi allelic G to A polymorphism at -308 upstream from the transcription initiation site of the promoter is associated with elevated TNF levels. The present study is aimed at evaluating the role of TNF-α-308 (G → A) gene polymorphism and susceptibility to GC. Subjects and Methods: A case-control study was carried out in 114 GC patients and 229 healthy control subjects. TNF-α genotyping at position-308 (G → A) was carried out by amplification refractory mutation system-polymerase chain reaction (ARMS-PCR) method followed by agarose gel electrophoresis. Results: The distribution of TNF-α genotypes at -308 (G → A) were GG 28.07%, GA 66.67% and AA 5.26% in GC patients and GG 33.19%, GA 55.89% and AA 10.92% in control subjects. The frequencies of alleles G and A were 0.614 and 0.386 in GC patients and 0.611 and 0.389 in control subjects respectively. Conclusion: The study showed no significant difference in the distribution of genotype and allelic frequencies between GC patients and control subject.
The Ex-Post Test of Corporate Governance Impact Toward Financial Distress and Financial Performance

After the crisis of 1998, the issue of Corporate Governance raises as indicator for investors and the government to see which company has the right direction in determining the failure and success of the company. By examining the impact of Corporate Governance in the top ten Corporate Governance Index with other companies that are not in top ten Corporate Governance Index, through financial distress, there were differences on the profitability value.
Establishment and Characterization of a Human Epstein-Barr Virus-Associated Gastric Carcinoma in SCID Mice

ABSTRACT A transplantable human Epstein-Barr virus-associated gastric carcinoma (EBVaGC), designated KT, was propagated in severe combined immunodeficiency (SCID) mice for 12 passages. Mucin and cytokeratin expression and the Alu sequence in tumor DNA confirmed that the KT tumor was derived from human epithelial tissue. The identity of clonal EBV in the original and KT tumors was demonstrated by terminal repeat analysis of EBV DNA. The pattern of latency gene expression of EBV was the same in both tumors. EBER1 was presented similarly in tumor cell nuclei by in situ hybridization. Reverse transcription-PCR analysis also demonstrated Q-promoter-driven EBNA1 expression but not BZLF1, EBNA2, or LMP1 expression. Thus, the transplantable human EBVaGC KT retains the original EBV with the same latency gene expression and can serve as a model for this unique type of gastric carcinoma.
Critical factors inhibiting Electronic Commerce (EC) adoption in Nigeria

Purpose – This study aims to develop adoption barriers model that captures location factors and non-transparency in government support programs, and attempted to unveil why certain locations offer more adoption opportunities than others. Design/methodology/approach – The opinions of small and medium enterprise (SME) owners/managers in the six geo-political zones of Nigeria were purposefully sampled. Two major cities (the commercial nerve center and a state capital) in each zone were chosen for the study and the data were analyzed using multiple regressions. Findings – Irrespective of the need to enhance operations through real-time knowledge sharing and network externalities; evidence from the study shows that SMEs in Nigeria are yet to exploit the full potentials of e-commerce solutions. This is evidenced by non-transparency in government support programs, location factors, weak finances, firm’s size, confidentiality of information, infrastructural inadequacy and lack openness and business integration. R.
Universal spectrum of normal modes in low-temperature glasses

Significance The vibrational spectrum of glasses displays an anomalous excess of soft, low-frequency modes with respect to crystals. Such modes are responsible for many anomalies in thermodynamic and transport properties of low-temperature glasses. Many distinct proposals have been formulated to understand their origin but none of them results from the analytic solution of a microscopically grounded model. Here we solve analytically the spectrum of a simple model that belongs to the same universality class of glasses, and identify two distinct mechanisms that are responsible for the soft modes. We report an analytical study of the vibrational spectrum of the simplest model of jamming, the soft perceptron. We identify two distinct classes of soft modes. The first kind of modes are related to isostaticity and appear only in the close vicinity of the jamming transition. The second kind of modes instead are present everywhere in the glass phase and are related to the hierarchical structure of the potential energy landscape. Our results highlight the universality of the spectrum of normal modes in disordered systems, and open the way toward a detailed analytical understanding of the vibrational spectrum of low-temperature glasses.
Burden and risk factors for gastrointestinal symptom distress in HIV patients in the modern antiretroviral era

ABSTRACT In the modern antiretroviral (ARV) era, there is limited knowledge about the prevalence and risk factors for HIV patient-reported gastrointestinal (GI) symptoms (diarrhoea/soft stool, nausea/vomiting, bloating/painful abdomen, loss of appetite, and weight loss/wasting) and distress. We prospectively analysed data (2007–2014) on distressing GI symptoms from the Ontario HIV Treatment Network Cohort Study, which follows people attending HIV clinics. Using generalized estimating equations with a logit link, we estimated the associations of psychosocial, demographic, behavioural, and clinical factors with each GI symptoms compared to asymptomatic and non-bothersome symptoms. Among 1532 included participants, 80.4% were male, mean age was 45 years, and 64.6% reported being men who have sex with men. Most were Caucasian (56.3%), a median time since HIV diagnosis of 9.8 years (interquartile range (IQR): 4.1–16.9), and 83.1% were on ARV. More than two-thirds (68.7% (95% confidence intervals (CI): 63.1% to 69.2%)) reported one or more symptoms with a median of 1.2 (IQR: 0–1.7). The proportion remained stable over time since HIV diagnosis and ARV initiation. Risk factors varied for multivariable models. A strong association with Centre for Epidemiologic Studies Depression scale scores of ≥23 was found for all symptoms. Adjusted odds ratios (95% CI) were 1.72 (1.39–2.12), 2.95 (2.33–3.72), 2.20 (1.81–2.68), 4.97 (3.99–6.19), and 2.98 (2.52–3.82) for diarrhoea, nausea/vomiting, bloating, loss of appetite, and weight loss, respectively. With the exception of bloating, odds were significantly lower for those on ARV containing integrase inhibitors and greater for patients reporting current cannabis use. GI symptoms in the modern ARV era are highly prevalent and may arise as a common pathway of distress in response to psychosocial vulnerabilities, regardless of the stage of diagnosis. These findings support the need for integrated approaches to address psychological and physical distress in HIV disease.
Moving beyond the Twitter follow graph

The study of the topological properties of graphs derived from social network platforms has a great importance both from the social and from the information point of view; furthermore, it has a big impact on designing new applications and in improving already existing services. Surprisingly, the research community seems to have mainly focused its efforts just on studying the most intuitive and explicit graphs, such as the follower graph of the Twitter platform, or the Facebook friends' graph: consequently, a lot of valuable information is still hidden and it is waiting to be explored and exploited. In this paper we introduce a new type of graph modeling behavior of Twitter users: the mention graph. Then we show how to easily build instances of this graphs starting from the Twitter stream, and we report the results of an experimentation aimed to compare the proposed graph with other graphs already analyzed in the literature, by using some standard social network analysis metrics.
Medicare Advantage 2014 Spotlight: Enrollment Market Update

This Data Spotlight provides an overview of Medicare Advantage enrollment patterns in March 2012, including variations by plan type, state, and firm. It also analyzes trends in premiums paid by beneficiaries enrolled in Medicare Advantage plans including variations by plan type, and describes out-of-pocket limits and prescription drug coverage in the Part D "doughnut hole" provided by the plans selected by beneficiaries.
Impact of yoga on haemodynamic function in healthy medical students.

OBJECTIVES Yoga improves cardiovascular health in both healthy individuals and those with diagnosed heart disease. This study compares changes in some cardiovascular parameters before and after the practice of Yoga in healthy medical students. METHODS Sixty-four healthy medical students (57 females and 7 males), mean age 21.3 +/- 2.6 years, attending a Special Study Module 'Role of Dhyana Yoga in Stress Management', participated in this study. Systolic (SYS) and Diastolic (DIA) blood pressure, Heart Rate (HR), Stroke Volume (SV), Cardiac output (CO), Total Peripheral Resistance (TPR), Interbeat Interval (IBI), Left Ventricular Ejection Time (LVET), Arterial Compliance (Cwk) and Ascending Aorta Impedance (Zao) were measured before and after six weeks of yogic exercises. Various exercises included asanas (Postures), pranayama (Breathing), and dhyana (Meditation). Data were analyzed using Stata for Windows. RESULTS Two-tailed paired t-test revealed that practice ofyoga caused significant increases in HR (p < 0.05), SV (p < 0.01), CO (p < 0.001) and Cwk (p < 0.01) and decreases in TPR (p < 0.001), IBI (p < 0.05) and Zao (p < 0.001) after practising yoga for 6 weeks as compared to before yoga practice. No significant differences were, however observed in SYS, DIA, Mean arterial blood pressure (MAP) and LVET CONCLUSIONS: Practice of yoga even for a short period showed ability to improve most of the cardiovascular functions. Regular practice of yoga for a longer period may further improve these functions and possibly result in improved management of their daily stress.
Kniest Dysplasia. A Histochemical Study of the Growth Plate

Summary: Chondro-osseous tissue from four patients with the Kniest dysplasia was studied histochemically using a new plastic embding technique. Extensive vacuolar changes were observed p-1 throughout the endochondral growth plate and adjacent resting cartilage. These changes occurred within the cartilage matrix and also in the lacunae of degenerating chrondrocytes. The septa of the lesions contained chondroitin sulfate, but little keratan sulfate or collagen. Resting cartilage not adjacent to the growth plate stained irregularly and showed few of the vacuolar lesions, and chondrocytes were enlarged and contained cytoplasic inclusions, but no vacuolar material. Thus, there appears to be a sequence of events initiated by cellular accumulation of a substance and progressing to cellular and matrix degeneration.Speculation: The findings suggest that there may be a defect in the synthesis, structure, or secretion of a major cartilage matrix component (e.g, proteoglycan, collagen) which leads to its accumulation in the chondrocyte rough endoplasmic reticulum. Both cellular and matrix degeneration subsequently occur either due to a toxic effect of this material or to the absence of the normal molecule.
A quantitative indirect immunofluorescent assay for zona pellucida antibodies.

A dilution series of a standard antiserum, raised in rabbit, against intact porcine oocytes was tested by an indirect immunofluorescent assay under a variety of conditions. Maximal antibody binding was obtained in phosphate-buffered saline with sucrose and sodium azide as a serum diluent and wash buffer, with relatively long incubation and wash periods, and in some cases heat-inactivation of sera. Factors found to influence the antibody binding were: alteration of the zonae by fixation; the presence of sucrose, galactose or glycerol; addition of protein to the buffer; heat inactivation of serum; substitution of phosphate by borate buffer; and replacement of the labelled second antibody by labelled Protein A. Antisera produced against acid- and heat-solubilized zonae differed from the standard antiserum in their binding capacity.l Control sera (anti-porcine spleen, adjuvant injected, and normal) were all completely negative.
Complement activation reaches maximum during equilibrium between antigen and antibody in an in vitro model for thrombolysis with streptokinase

Treatment with streptokinase (SK) of patients with acute myocardial infarction (AMI) is known to activate the complement system. In a previous investigation we found a great variation in the degree of complement activation taking place during infusion of SK in patients with AMI (range: 0–293% increase in pretreatment complement split product 3d (C3d) levels). In this in vitro study we added SK to serum with different concentrations of SK‐antibodies (SK‐Ab) and found that both the relative concentrations and the total concentrations of SK and Ab determined the degree of complement activation elicited by SK. This finding was in accordance with the Kendall‐Heidelberger equation of antigen‐antibody equivalence. Furthermore, we found parallel rises in C3d and C4d, indicating that complement was activated via the classical pathway. A condition for maximal complement activation is antigen‐antibody equivalence.
Canine Splenic Pathology : a Retrospective Study of 109 Surgical Samples , with Special Emphasis on Fibrohistiocytic Nodules

In order to assess the relevance of canine splenic pathology, to emphasise the differential diagnostic criteria among splenic haematoma, haemangioma and haemangiosarcoma, and to focus on the recently proposed classification of canine splenic fibrohistiocytic nodules (FHN), a retrospective study was carried out on HE-stained sections from formalin-fixed and paraffin-embedded samples from 109 spleens after splenectomy. FHN were also stained by Masson trichrome, Gomori for reticulin, Perls for hemosiderin, toluidine blue and immunohistochemistry (CD3, BLA.36, MAC.387, lysozyme, F-VIII-RA, S100, vimentin, desmin, sm-actin and MIB-1). Spleens were resected because of diffuse splenomegaly (49%) or nodular distortion (51%). Microscopic changes consisted of myeloid metaplasia and erythrophagocytosis in 25 cases (23%), hyperemia (13%), haematoma (9%), haemangioma (4%), haemangiosarcoma (11%), nodules of combined lymphoid and fibrohistiocytic cell proliferation (16%), secondary lymphoma (7%), metastasis of carcinoma (4%), splenitis (5%) and others lesions (10%). Splenectomy is a “common procedure” in the dog, but it is usually performed without a definitive clinical diagnosis and prognosis, which necessitate subsequent histopathologic examination. The differential diagnosis between splenic haematoma and haemangiosarcoma can be very difficult if the surgical specimen is not correctly sampled. The histological pattern of FHN ranged from nodules of lymphoid hyperplasia including a distinct population of spindle and/or histiocytic cells sometimes displacing the follicular architecture of the nodule, up to true fibrohistiocytic neoplasms. Morphology and immunohistochemistry seem to prove that FHN are a continuum from benign nodular hyperplasia to malignant fibrous histiocytoma.
Usage and success factors of commercial recommendation agents

Purpose – Since their inception, which took place more than two decades ago, product recommendation agents (RAs) still attract very few consumers. Notably, most of academic work in the field had an empirical quantitative structure. In addition, no research has developed a comprehensive model to explain the adoption and usage of commercial RAs. The purpose of this paper is to follow a qualitative approach to investigate the factors behind the adoption and usage of commercial RAs, explore the effect of user age, and deduce the success factors of these RAs.Design/methodology/approach – This research followed a qualitative approach. Qualitative research aims to form an in‐depth understanding of human behavior. It is essential for building grounded theory and for proposing comprehensive models for future examination. As such, in four discussion groups, participants provided their input following the shopping trial for a product using a factual RA (MyProductAdvisor.com). Discussion groups were used because they.
Tocilizumab Monotherapy Reduces Arterial Stiffness as Effectively as Etanercept or Adalimumab Monotherapy in Rheumatoid Arthritis: An Open-label Randomized Controlled Trial

Objective. To compare the respective effects of tocilizumab (TCZ) monotherapy, etanercept (ETN) monotherapy, and adalimumab (ADA) monotherapy on arterial stiffness in patients with rheumatoid arthritis (RA) in an open-label, randomized controlled trial. Methods. Patients with RA were eligible if they had active disease (28-joint Disease Activity Score > 3.2) and no prior treatment with methotrexate or biologics. All 64 patients had no history of cardiovascular disease or steroid treatment. Patients were randomly assigned to receive TCZ alone (n = 22), ETN alone (n = 21), or ADA alone (n = 21). Arterial stiffness was assessed with cardio-ankle vascular index (CAVI) and aortic augmentation index normalized to a fixed heart rate of 75 bpm (AIx@75) at baseline and 24 weeks’ followup. Clinical data were collected at regular visits. Results. The characteristics of each group at baseline were not significantly different. In all groups there was significant attenuation from baseline to 24 weeks in CAVI (Week 0-Week 24, TCZ: 0.85 ± 0.15 m/s, p = 0.02; ETN: 0.81 ± 0.18 m/s, p = 0.03; ADA: 0.90 ± 0.21 m/s, p = 0.02) and in AIx@75. There were no significant differences among the groups in measures of CAVI or AIx@75. The 3 therapies made no difference to carotid intima-media thickness and carotid artery plaque. Only TCZ increased fasting serum total cholesterol from baseline to 24 weeks. Conclusion. The 3 types of monotherapy limited arterial stiffness in patients with RA to a similar extent.
Chewing Gum after Cesarean Section : It ' s Effect on Regaining Intestinal Function Suzan

Aim: This study aimed to evaluate the effect of chewing gum after cesarean section on regaining intestinal function. Design: Randomized controlled trial. Setting: Study was conducted at post-partum ward at Mansoura University Hospital. Subjects: Eighty pregnant women underwent elective cesarean section and fulfilled the inclusion criteria; were divided equally by simple randomization into the study group (n=40) women chewed sugar free gum for 30 minute every 2 hours starting two hours after cesarean section and the control group (n=40) women received standard post-operative care. Tools: Two tools were used for data collection (Structured Interviewing schedule and PostOperative Cesarean Section Assessment Sheet which used to assess the post-operative intestinal parameters). Results: There was no statistically significant difference between the study group and the control group regarding their general characteristics. Nevertheless, there was statistically significant difference in the mean of intestinal function, whereas the mean interval of intestinal parameters was statistically significant shorter in favor of the study group compared to the control group. The first time of hearing intestinal sound was (3.93±1.02 vs. 4.87±1.96, p= 0.008), the first passage of gas was (6.54±1.37 vs. 7.65±2.42, P=0.013), the first hungry feeling was (7.63±2.24 vs. 8.83±3.18, P=0.024), the first defecation was (10.25±2.15 vs. 11.58±1.96, P=0.031), the first eat was (11.60±2.03 vs. 14.08±3.58, P=0.000) and time of hospital discharge was (18.18±4.79 vs. 21.15±3.42, P=0.002) respectively. Moreover, there was a significant correlation between the time of the first eating and the time of discharge (r = 0.614, p = 0.000). In conclusion: It was evident that chewing gum is considered an effective and inexpensive method that can be used to shorten the time and hasten regaining of intestinal function after cesarean section. Recommendations: Integrating chewing gum in nursing care protocol for caring women after cesarean section.