Miracle-dz/UniFAR-FTUs huggingface dataset:
Quantitative Analysis of Planar Laser-Induced Fluorescence Measurements in a Hypersonic Boundary Layer

Several quantitative measurements extracted from nitric oxide (NO) planar laser-induced fluorescence (PLIF) data obtained in a hypersonic boundary layer are reported: (a) off-body NO mole fraction; (b) surface heat flux; and (c) near-wall static temperature. The experimental data was obtained at NASA Langley Research Center’s 31 in. Mach 10 air tunnel. NO was seeded into the flow through a spanwise slot on the surface of the 10 degree half-angle wedge model. An ultraviolet planar laser sheet was positioned perpendicular to the wedge surface, downstream of the seeding slot, to excite six fluorescence transitions. A method for extracting the relative NO mole fraction, based on spatial variations of the J”= 0.5 PLIF signal, is presented. Combined with the principle of mass conservation, the absolute NO mole fraction is determined. These measurements were used to assess CFD diffusion modelling, correct previously reported PLIF thermometry results, and develop methods for NO-PLIF heat transfer measurements.
Characteristics and predictors of breast milk iodine in exclusively breastfed infants: Results from a repeated-measures study of iodine metabolism

Background The iodine supply of exclusively breastfed infants entirely depends upon breast milk. Changes in breast milk iodine affect infants’ iodine nutritional status. This study aimed to comprehensively assess the characteristics and predictors of breast milk iodine concentration (BMIC). Materials and methods This 7-day iodine metabolism experiment was conducted in 25 exclusively breastfed mother-infant pairs. The duplicate portion method was used to measure the mother’s daily iodine intake from foods and water, and maternal 24-h urine excretion was assessed. We recorded the number of breastfeeds per mother per day and collected breast milk samples before and after each feeding. Results The median [quartile (Q)1–Q3 range] of BMIC was 115 (86.7, 172) μg/L. The BMIC before breastfeeding was generally higher than that after breastfeeding. Time-sequential analysis found that morning BMIC was most highly correlated with the prior day’s iodine intake. Breast milk samples taken in the afternoon or after midnight are closer to the median level of BMIC throughout the day. The number of breast milk samples needed to estimate the iodine level with 95% CI within precision ranges of ± 20% was 83 for a population, 9 for an individual, and 2 for an individual’s single day. Maternal total iodine intake (TII) and urine iodine were significantly associated with BMIC. 24-h urinary iodine excretion (24-h UIE) was found to be the best predictive indicator for the BMIC (β = 0.71, 95% CI: 0.64, 0.79). Conclusion BMIC is a constantly changing indicator and trended downward during each breastfeeding. Breast milk samples taken in the afternoon or after midnight are most representative. BMIC was significantly associated with recent iodine intake. Maternal 24-h UIE was the best predictor of BMIC.
Modelling zoonotic diseases, cooperation between spreading and spontaneous infection

Many infectious processes, such as human diseases or computer viruses, spread across complex networks following directed links. While in some cases there exists a clear separation of timescales between the propagation of one outbreak and the initiation of the next, there are also processes for which this is not the case, such as zoonotic diseases. For a large class of relevant network topologies, we show here that if the rate of spontaneous activation of a new outbreak becomes sufficiently similar to the propagation rate of an individual outbreak such that outbreaks start to overlap and interact, the nature of the overall infectious spreading fundamentally changes. This change manifests itself in a transition between different universality classes of critical spreading, which determines the onset and the properties of an outbreak turning epidemic or even pandemic. We present analytical results in the mean-field limit giving the critical line along which scale-free spreading behaviour can be observed. The two limits of this critical line correspond to the universality classes of directed and undirected percolation, respectively. Outside these two limits, this duality manifests itself in the appearance of critical exponents from the universality classes of both directed and undirected percolation. We find that the transition between these exponents is governed by a competition between merging and propagation of activity, and identify an appropriate scaling relationship for the transition point.
A motivational approach to perfectionism and striving for excellence: Development of a new continuum-based scale for post-secondary students

Perfectionism has been the object of many disputes. One such debate pertains to the nature of perfectionistic strivings. Whereas perfectionistic concerns (PC) have been shown to correlate with negative outcomes, perfectionistic strivings (PS) have been associated with mixed outcomes. This view of perfectionism assumes a motivational perspective; however, commonly used questionnaires assess motivation only implicitly. To create a more explicit measure of motivation as regard perfectionism, we aimed to assess perfectionism in post-secondary education based on Deci and Ryan’s self-determination continuum. We posit that introjected motivation represents the variance common to both dimensions of perfectionism. External motivation is considered to be specific to PC and identified motivation to PS. Amotivation represents a lack of meaningful striving. Intrinsic motivation, lacking perfectionism’s pressure, is conceptualized to be a self-determined form of striving for excellence. We further posited that this continuum is implicitly underlain by a continuum of self-definition as defined by Blatt. The resulting questionnaire showed an adequate structure with ESEM, followed a simplex structure, and had adequate reliabilities (Study 1a/Study 2). It also showed adequate convergent validity (Study 1b/Study 2). Finally, the questionnaire proved to be invariant over a 6-week period (Study 2). Results suggest that the degree of active goal pursuit, in addition to standards setting, could be a distinguishing characteristic between dimensions of perfectionism as well as striving for excellence.
Social media use, social identification and cross-cultural adaptation of international students: A longitudinal examination

The mobility experience is an important life event for international students, and achieving successful psychological and sociocultural adaptation is crucial for this experience to be positive. Through a three-wave longitudinal study among international students enrolled at universities in Spain, Portugal, and Poland (n = 233), we examined the relationships between social media use, social identification, and (sociocultural and psychological) adaptation across time. Results of cross lagged panel modeling (CLPM) showed that social media contact with home nationals predicted greater identification with this group. Social media contact with host country nationals predicted poorer adaptation. Social media contact with other international students did not show any effects, while identification with this group predicted better adaptation. Our results point to the dynamic nature of the adaptation process, showing that the role of social media use and identification targeted at different social groups may play different roles than was previously found in cross-sectional research.
A novel dental infiltration resin based on isosorbide-derived dimethacrylate with high biocompatibility, hydrolysis resistance, and antibacterial effect

Objectives: The available infiltration resin has raised biosafety and treatment stability concerns because of the cytotoxicity of the main component, TEGDMA, and its susceptibility to hydrolysis in the oral environment. This study aimed to develop a TEGDMA-free infiltration resin to overcome these drawbacks. Methods: Using the synthetic bioderived monomer bis(methacrylate) isosorbide (IBM) and the zwitterionic compound 2-methacryloyloxyethyl phosphorylcholine (MPC), a novel infiltrant IBMA was developed and preferentially selected. We investigated the performance of the IBMA resin regarding cytotoxicity, antibiofilm adhesion, and hydrolysis resistance and further verified its ability to restore the demineralized enamel and stability of the infiltrated area under artificial aging conditions. Results: Compared with the commercial TEGDMA-based infiltration resin ICON, IBMA not only demonstrated similar enamel morphologic and esthetic restorative effects in chalky lesions but also exhibited favorable cell viability, durable Streptococcus mutans UA159 biofilm-repellent performance, and higher enamel microhardness (204.0 ± 5.12 HV) of the infiltrated enamel. Specifically, because of the high crosslink density [(47.77 ± 5.76) ×103 mol/mm3] and low water sorption [12.79 ± 2.56 µg/mm3] of the polymer network, the IBMA resin was more resistant to hydrolysis than ICON, which prevents the disruption of the infiltrant’s micropore-blocking effect after aging. Enamel lesions treated with IBMA demonstrated good color stability after the tea-staining challenge, which was significantly better than that in the ICON group. Conclusion: Based on these findings, the IBMA resin exhibits favorable cell viability, hydrolysis resistance, and biofilm-repellent properties, which alleviates the defects of traditional TEGDMA systems. Therefore, it is a better alternative for microinvasive treatment involving early caries and enamel whitish discoloration.
Recognizing the role of the vagus nerve in depression from microbiota-gut brain axis

Depression is a worldwide disease causing severe disability, morbidity, and mortality. Despite abundant studies, the precise mechanisms underlying the pathophysiology of depression remain elusive. Recently, cumulate research suggests that a disturbance of microbiota-gut-brain axis may play a vital role in the etiology of depression while correcting this disturbance could alleviate depression symptoms. The vagus nerve, linking brain and gut through its afferent and efferent branches, is a critical route in the bidirectional communication of this axis. Directly or indirectly, the vagus afferent fibers can sense and relay gut microbiota signals to the brain and induce brain disorders including depression. Also, brain changes in response to stress may result in gut hyperpermeability and inflammation mediating by the vagal efferents, which may be detrimental to depression. Notably, vagus nerve stimulation owns an anti-inflammatory effect and was proved for depression treatment. Nevertheless, depression was accompanied by a low vagal tone, which may derive from response to stress and contribute to pathogenesis of depression. In this review, we aim to explore the role of the vagus nerve in depression from the perspective of the microbiota-gut-brain axis, highlighting the relationship among the vagal tone, the gut hyperpermeability, inflammation, and depression.
Experimental warming increases fungal alpha diversity in an oligotrophic maritime Antarctic soil

The climate of maritime Antarctica has altered since the 1950s. However, the effects of increased temperature, precipitation and organic carbon and nitrogen availability on the fungal communities inhabiting the barren and oligotrophic fellfield soils that are widespread across the region are poorly understood. Here, we test how warming with open top chambers (OTCs), irrigation and the organic substrates glucose, glycine and tryptone soy broth (TSB) influence a fungal community inhabiting an oligotrophic maritime Antarctic fellfield soil. In contrast with studies in vegetated soils at lower latitudes, OTCs increased fungal community alpha diversity (Simpson’s index and evenness) by 102–142% in unamended soil after 5 years. Conversely, OTCs had few effects on diversity in substrate-amended soils, with their only main effects, in glycine-amended soils, being attributable to an abundance of Pseudogymnoascus. The substrates reduced alpha and beta diversity metrics by 18–63%, altered community composition and elevated soil fungal DNA concentrations by 1–2 orders of magnitude after 5 years. In glycine-amended soil, OTCs decreased DNA concentrations by 57% and increased the relative abundance of the yeast Vishniacozyma by 45-fold. The relative abundance of the yeast Gelidatrema declined by 78% in chambered soil and increased by 1.9-fold in irrigated soil. Fungal DNA concentrations were also halved by irrigation in TSB-amended soils. In support of regional- and continental-scale studies across climatic gradients, the observations indicate that soil fungal alpha diversity in maritime Antarctica will increase as the region warms, but suggest that the accumulation of organic carbon and nitrogen compounds in fellfield soils arising from expanding plant populations are likely, in time, to attenuate the positive effects of warming on diversity.
Assessing Marine Nitrogen Cycle Rates and Process Sensitivities With a Global 3‐D Inverse Model

We present results from a global inverse marine nitrogen (N) cycle model that include nitrate (NO3−) and nitrite (NO2−) concentrations and their N isotopic compositions as constraints on N cycle process rates in marine oxygen deficient zones (ODZs). NO2− is an important intermediate in the N cycle, particularly in ODZs where it is a substrate in the N loss processes, denitrification, and anammox. Similar to earlier work, our model yields a total water column N loss rate of 61 ± 10 Tg N/year. However, by including NO2− and its N isotopic composition, we are able to assess the relative contributions of denitrification and anammox to N loss and examine some of the potential drivers of that balance. We find that anammox contributes 60% of global water column N loss, dominating N loss along the edges of ODZs, while denitrification is more important in the anoxic ODZ cores. The decoupling of anammox and denitrification is supported by NO2− oxidation, which co‐occurs with NO3− reduction and anammox in ODZs. High rates of NO2− oxidation (up to 400 nM/day), which are tightly coupled to heterotrophic NO3− reduction, are required to match NO3− and NO2− concentration and isotope observations in marine ODZs. Lowering the rate of NO2− oxidation in ODZs by adjusting O2‐sensitive parameters results in higher rates of water column N loss, highlighting the role of NO2− oxidation in maintaining the marine fixed N inventory.
133,000 Years of Sedimentary Record in a Contourite Drift in the Western Alboran Sea: Sediment Sources and Paleocurrent Reconstruction

The Djibouti Ville Drift is part of a contourite depositional system located on the southern side of the Djibouti Ville Seamount in the Alboran Sea (Western Mediterranean). The sedimentary record of a core located in the drift deposits has been characterized to achieve the possible sediment sources for the Saharan dust supply and the paleocurrent variability related to Mediterranean intermediate waters for the last 133 kyr. Three end-member grain-size distributions characterize the sediment record transported by the bottom current to address the different aeolian populations, i.e., coarse EM1, silty EM2, and fine EM3. For these particles, the most likely source areas are the Saharan sedimentary basins and deserts, as well as the cratonic basins of the Sahara-Sahel Dust Corridor. The prevalence of these main source areas is shown in the core record, where a noticeable change occurs during the MIS 5 to MIS 4 transition. Some punctual sediment inputs from the seamount have been recognized during sea-level lowstand, but there is no evidence of fluvial supply in the drift deposits. The paleocurrent reconstruction allows the characterizing of the stadial and cold periods by large increases in the mean sortable silt fraction and UP10, which point to an enhanced bottom current strength related to intermediate water masses. Conversely, interglacial periods are characterized by weaker bottom current activity, which is associated with denser deep water masses. These proxies also recorded the intensified Saharan wind transport that occurred during interstadial/stadial transitions. All these results point to the importance of combining sediment source areas with major climatic oscillations and paleocurrent variability in palaeoceanographic sedimentary archives, which may help to develop future climate prediction models.
Multi-task trust transfer for human–robot interaction

Trust is essential in shaping human interactions with one another and with robots. In this article we investigate how human trust in robot capabilities transfers across multiple tasks. We present a human-subject study of two distinct task domains: a Fetch robot performing household tasks and a virtual reality simulation of an autonomous vehicle performing driving and parking maneuvers. The findings expand our understanding of trust and provide new predictive models of trust evolution and transfer via latent task representations: a rational Bayes model, a data-driven neural network model, and a hybrid model that combines the two. Experiments show that the proposed models outperform prevailing models when predicting trust over unseen tasks and users. These results suggest that (i) task-dependent functional trust models capture human trust in robot capabilities more accurately and (ii) trust transfer across tasks can be inferred to a good degree. The latter enables trust-mediated robot decision-making for fluent human–robot interaction in multi-task settings.
Intersection times for critical branching random walk

We present results relating mixing times to the intersection time of branching random walk (BRW) in which the logarithm of the expected number of particles at time $t$ grows like $ \mathrm{gap} \cdot t $. This is a finite state space analog of a critical branching process. Namely, we show that the maximal expected hitting time of a state by such a BRW is up to a universal constant larger than the $L_{\infty}$ mixing-time, whereas under transitivity the same is true for the intersection time of two independent such BRWs. Using the same methodology, we show that for a sequence of reversible Markov chains, the $L_{\infty}$ mixing-times $t_{\mathrm{mix}}^{(\infty)} $ are of smaller order than the maximal hitting times $t_{\mathrm{hit}}$ iff the product of the spectral-gap $\mathrm{gap}$ and $t_{\mathrm{hit}}$ diverges, by establishing the inequality $t_{\mathrm{mix}}^{(\infty)} \lesssim \frac{1}{\mathrm{gap}}\log(1+t_{\mathrm{hit}} \cdot \mathrm{gap}) $. This resolves a conjecture of Aldous and Fill (Reversible Markov chains and random walks on graphs, Open Problem 14.12) asserting that under transitivity the condition that $ t_{\mathrm{hit}} \gg \frac{1}{\mathrm{gap}} $ implies mean-field behavior for the coalescing time of coalescing random walks.
Probiotics for constipation in Parkinson’s: A systematic review and meta-analysis of randomized controlled trials

Background Parkinson’s disease (PD)-related constipation may affects both disease occurrence and disease progression. Probiotics, as a potential therapeutic intervention, have attracted the attention of researchers, but the evidence of their efficacy and safety has not been systematically reviewed. Aim A systematic review and meta-analysis of randomized controlled trials of probiotics in the treatment of PD constipation was conducted to determine the efficacy and safety of probiotics in the treatment of PD constipation. Methods Four databases (The Cochrane Central Register of Controlled Trials, Embase, PubMed, and Web of Science) were searched from their establishment to June 1, 2022. We included randomized controlled trials of probiotics for the treatment of constipation in patients with PD, with probiotics in the experimental group and a placebo, another treatment, or no treatment in the control group. The primary outcome was the number of bowel movements per week. Secondary outcomes included nonmotor symptoms (NMS), gut transit time (GTT), abdominal pain, abdominal distention, constipation, and quality of life scores. Stata15.1 was used to generate a summary of the data and perform a descriptive analysis if necessary. The GRADE tool was used to assess the quality of the evidence and the Cochrane guidelines to assess the risk of bias for each study. Results Finally, four qualified RCTs were included, comprising 287 participants. Compared with the control group, probiotics could effectively increase the frequency of defecation per week in PD patients (WMD = 1.02. 95%CI: 0.56–1.48, and P < 0.00001), but the heterogeneity was high, and the quality of the evidence was low. There was no significant difference in average stool consistency between patients with PD treated with probiotics and those given a placebo in (WMD = –0.08. 95%CI: –1.42–1.26, and P = 0.908). In addition, the results suggested that probiotics have no obvious effect on additional indicators of gastrointestinal dysfunction, such as GTT, abdominal pain, and abdominal distension, and there is insufficient evidence on their ability to improve NMS and Parkinson’s disease Questionnaire 39 summary indices (PDQ39-SI). Safety issues should be carefully explained. Conclusion There is insufficient evidence supporting the use of probiotics to treat constipation in patients with PD. Taking all the results together, probiotics have potential value in the treatment of PD-related constipation. Systematic Review Registration PROSPERO CRD42022331325.
Dynamic allometry in coastal overwash morphology

Abstract. Allometry refers to a physical principle in which geometric (and/or metabolic) characteristics of an object or organism are correlated to its size. Allometric scaling relationships typically manifest as power laws. In geomorphic contexts, scaling relationships are a quantitative signature of organization, structure, or regularity in a landscape, even if the mechanistic processes responsible for creating such a pattern are unclear. Despite the ubiquity and variety of scaling relationships in physical landscapes, the emergence and development of these relationships tend to be difficult to observe – either because the spatial and/or temporal scales over which they evolve are so great or because the conditions that drive them are so dangerous (e.g. an extreme hazard event). Here, we use a physical experiment to examine dynamic allometry in overwash morphology along a model coastal barrier. We document the emergence of a canonical scaling law for length versus area in overwash deposits (washover). Comparing the experimental features, formed during a single forcing event, to 5 decades of change in real washover morphology from the Ria Formosa barrier system, in southern Portugal, we find differences between patterns of morphometric change at the event scale versus longer timescales. Our results may help inform and test process-based coastal morphodynamic models, which typically use statistical distributions and scaling laws to underpin empirical or semi-empirical parameters at fundamental levels of model architecture. More broadly, this work dovetails with theory for landscape evolution more commonly associated with fluvial and alluvial terrain, offering new evidence from a coastal setting that a landscape may reflect characteristics associated with an equilibrium or steady-state condition even when features within that landscape do not.