Miracle-dz/UniFAR-FTUs huggingface dataset:
The relationship between the board of directors and firm performance in private family firms: A test of the demographic versus behavioral approach

Abstract Research on corporate governance has attempted to investigate the added value of boards of directors through the lenses of both demographic and behavioral approaches. However, investigations into these two approaches, and the subsequent implications for firm performance, have thus far been mainly decoupled from one another. Therefore, the aim of this paper is to put both approaches to the test in the family business context. Using a sample of 567 Spanish family firms, we find that although both approaches can explain the performance of family firms, the behavioral approach explains a much higher proportion of the variation in the firm’s performance. Furthermore, our findings support our hypotheses that the relationship between the proportion of outside directors and firm performance follows an inverted U-shape in private family firms, and that both business-oriented and family-oriented board role performance are positively related with firm performance.
HIV-Inducing Factor in Cervicovaginal Secretions Is Associated With Bacterial Vaginosis in HIV-1-Infected Women

Objective:Certain cervicovaginal lavage (CVL) fluid samples obtained from HIV-1-infected and uninfected women stimulate in vitro HIV-1 replication. This activity, HIV-inducing factor (HIF), changes when CVL fluid is heated. We sought to confirm a previous observation that HIF was associated with bacterial vaginosis (BV). Methods:HIF was measured in unheated and heated CVL fluid obtained from HIV-1-infected women and compared with the presence of BV by Nugent scores, other genital tract conditions, and cervicovaginal HIV-1 shedding. Results:Among the 295 women studied, 54% of CVL samples had HIF activity and 21% showed heat-stable HIF activity. In adjusted logistic regression, heat-stable HIF was associated with BV (odds ratio [OR] = 51.7, 95% confidence interval [CI]: 5.0, 530.7) and with intermediate flora (OR = 43.3, 95% CI: 3.6, 521.1); heat-labile HIF was not associated with BV. Neither heat-stable nor heat-labile HIF was associated with other cervicovaginal conditions nor, after controlling for plasma viral load, with genital tract HIV-1 shedding. Conclusion:We confirmed the association of HIF with BV and attribute it to the heat-stable component. Heat-stable activity is also associated, although less strongly, with intermediate vaginal flora. We propose that heat-stable HIF is a result of products of BV-associated bacteria.
NARX models of an industrial power plant gas turbine

This brief reports the experience with the identification of a nonlinear autoregressive with exogenous inputs (NARX) model for the PGT10B1 power plant gas turbine manufactured by General Electric-Nuovo Pignone. Two operating conditions of the turbine are considered: isolated mode and nonisolated mode. The NARX model parameters are estimated iteratively with a Gram-Schmidt procedure, exploiting both forward and stepwise regression. Many indexes have been evaluated and compared in order to perform subset selection in the functional basis set and determine the structure of the nonlinear model. Various input signals (from narrow to broadband) for identification and validation have been considered.
A Mechanism for the Decrease in Stiffness of Bioprosthetic Heart Valve Tissues After Cross‐Linking

&NA; It has been reported that the elastic modulus of glutaraldehyde treated bioprosthetic valve materials is lower than that of fresh tissues. This finding appears paradoxic, because cross‐linked tissues are usually stiffer than fresh ones. To investigate this phenomenon, the stiffness of 12 each of fresh and glutaraldehyde treated strips of porcine aortic valve cusps was measured at different levels of applied preload. To eliminate shrinkage effects, tissues were fixed while constrained at the gauge length. From paired comparisons of fresh versus fixed, it was found that glutaraldehyde fixed materials had a consistently lower stiffness than fresh tissue at low loads (0.39 N/m for treated vs 0.54 N/m for fresh at a 150 N/m preload), but no difference was found at high loads (1.09 N/m for treated vs 1.07 N/m for fresh at 600 N/m preload). It is concluded that the observed drop in elastic modulus at low loads is a phenomenon associated with cross‐linking of the collagen fiber matrix. Because a cross‐linked matrix offers greater resistance to stretch, fixed tissue generates higher tensions at lower strains, at a point on the loading curve where the collagen fibers are more crimped and the slope of the curve is lower. At high loads, however, the stiffness of fixed tissues is equivalent to that of fresh. Measuring stiffness at a given stress or tension, rather than at a particular state of collagen fiber crimp, leads to the apparent lower stiffness of fixed tissues. ASAIO Journal 1996;42:993‐999.
Asthma severity and atopy: how clear is the relationship?

Background: The relationship between asthma severity and atopy is complex. Many studies have failed to show significant relationships between clinical severity or lung function and markers of atopic sensitisation. Aim: To determine whether increasing asthma severity is related to atopic sensitisation in a population of children with asthma. Methods: A total of 400 children (7–18 years) with asthma were recruited as part of a multicentre study of the genetics of asthma. Detailed phenotypic data were collected on all participants. Associations between measures of asthma severity and atopic sensitisation were sought using multilevel models allowing variation at the individual and family level. Results: Children recruited to the study had a range of asthma severities, with just over a third having mild persistent asthma. The logarithm of total serum IgE was associated with increased asthma severity score, decreased FEV1, increased airways obstruction, risk of hospital admission, and inhaled steroid use. Increasing skin prick test reactivity to a panel of seven aeroallergens was associated with increased risk of hospital admission, use of an inhaled steroid, and airways obstruction. The results remained highly significant after corrections for age, gender, and birth order. Conclusions: In children with asthma, increasing atopy is associated with increasing asthma severity. However, the relationships between asthma severity and skin prick tests, and asthma severity and total serum IgE values, appear subtly different.
Morphometric MRI evaluation of corpus callosum and ventricles in normal adults

Abstract Objectives: The aim of this study was to determine the normal values of subregions of corpus callosum and ventricles in healthy adult people in our population using magnetic resonance imaging (MRI) and to establish gender differences. Methods: The MRI of 52 healthy individuals (29 females and 23 males) aged 20-50 years was obtained. The measurements were performed from MRI on a workstation. The midsagittal images were used for measurements of the subregions of corpus callosum and axial images were for lateral and third ventricles. Results: The mean values of the widths of genu, body, splenium, and height of the corpus callosum were 13·28±2·10, 7·64±1·07, 12·52±1·35, and 25·47±2·20 mm, respectively in females; whereas, the same measurements were 13·23±2·41, 6·89±2·12, 11·90±1·94, and 25·03±3·38 mm, respectively in males. Moreover, the mean value for the longitudinal dimension of the brain was 150·12±5·04 mm, while that for the corpus callosum was 71·27±3·70 mm in females. Additionally, the mean frontal horn width of the lateral ventricle and the transverse inner diameter of the skull were 34·06±3·05 and 130·76±6·71 mm in females and 34·03±2·78 and 129·96±10·61 mm in males, respectively. Due to these measurements, the values of Evans index which is reflecting the lateral ventricle enlargement were estimated to be 0·25±1·90 and 0·25±1·14 in females and males, respectively. According to our last measurement result, the mean values for the third ventricle width were 3·79±0·85 and 4·12±0·94 mm in females and males, respectively. These findings show that there are differences between the averages of some indices of corpus callosum of our population and the other populations.
Blood Lipids in Brain Infarction Subtypes

Background: Little is known about the relationship between hypercholesterolaemia and specific aetiological subtypes of brain infarction (BI). Methods: In a cross-sectional study of 492 pairs of patients with a BI proven by MRI and matched hospital controls, we determined the blood levels of triglycerides, total, HDL and LDL cholesterol, and apolipoprotein A1 and B, in the same centralized laboratory. We performed aetiological BI subtype classification. Results: Except for triglycerides, the risk of BI increased continuously with the lipid levels, without any heterogeneity between the main BI subtypes or the group on lipid-lowering therapy. The adjusted odds ratio per standard deviation in LDL cholesterol (0.93 mmol/l) was 1.74 (95% confidence interval, 1.02–2.98) in atherothrombotic strokes (n = 109) and 2.71 (95% confidence interval, 1.60–4.55) in lacunar strokes (n = 105). Eighty percent of patients were above the ATP-III guideline threshold LDL cholesterol of 2.59 mmol/l (100 mg/dl), with a major contribution of both atherothrombotic and lacunar stroke subtypes to this group. Conclusions: These findings suggest that blood lipids, particularly total and LDL cholesterol levels, are associated with all subtypes of BI, and that LDL above 2.59 mmol/l is highly prevalent.
Insulitis and Diabetes are Preceded by a Decrease in p Cell Volume in Diabetes‐prone BB Rats

Immunocytochemistry combined with morphometry was used to test the hypothesis that insulitis and diabetes are preceded by quantitative changes in the pancreas of diabetes-prone BB (DPBB) rats. Diabetes-resistant BB (DRBB) rats of the w-subline served as controls. In the first part of the study rats aged 15,30,45, and 60 days were studied. At 60 days preceding both insulitis and onset of diabetes, the DPBB rats demonstrated lower volumes of the entire pancreas, the parenchyma, the endocrine pancreas, and β, A, and D cells. Body weights of the DPBB rats were lower than the DRBB rats from 15 days of age on. In the second part of the study, DP and DRBB rats were coreared by a foster mother to obtain weight-matched animals. Morphometric analysis at 70 days of age revealed a reduction in both the β cell volume density and volume whereas no differences were seen in other pancreatic parameters. These results indicate that the appearance of insulitis and the later onset of insulin-dependent diabetes are preceded by a reduction in β cell volume.
Methylene Tetrahydrofolate Reductase Genotype Modifies the Chemopreventive Effect of Folate in Colorectal Adenoma, but not Colorectal Cancer

Epidemiologic evidence suggests a role for folate, a critical component of the 1-carbon cycle, in colorectal adenoma and cancer pathogenesis. Low folate levels, along with genetic polymorphisms in key enzymes such as methylene tetrahydrofolate reductase (MTHFR), can cause DNA hypomethylation and aberrant CpG methylation, which have been associated with colorectal tumor development. We investigated self-reported folate and alcohol intake alongside possible modifying effects of MTHFR 677 C>T and 1298 A>C polymorphisms in UK case-control studies of colorectal adenoma (317 cases, 296 controls) and cancer (500 cases, 742 controls). A significant association between MTHFR 1298 and colorectal cancer risk was observed [odds ratio, 1.57; 95% confidence interval (95% CI), 1.05-2.37], which was more pronounced in males (odds ratio, 3.02; 95% CI, 1.63-5.62). Although we found no association between MTHFR 677 and colorectal cancer, when data were stratified by sex, an increased risk was seen in females (odds ratio, 1.96; 95% CI, 1.11-3.46) but not in males. High folate intake was associated with a decreased risk for colorectal adenoma (odds ratio, 0.47; 95% CI, 0.30-0.73; Ptrend, <0.001), which was modified by MTHFR 1298 genotype (Pinteraction = 0.006). However, we found no evidence to support the hypothesis that a high-folate diet protects against colorectal cancer development. Consistent with previous studies, high alcohol intake (≥14 U/wk) was associated with a significantly increased cancer risk (odds ratio, 2.57; 95% CI, 1.81-3.64). Our data suggest that dietary folate intake may be an important determinant for premalignant colorectal disease development but not colorectal cancer, an association that is modified by MTHFR genotype. (Cancer Epidemiol Biomarkers Prev 2008;17(9):2421–30)
Determinants of information behaviour and information literacy related to healthy eating among Internet users in five European countries

Introduction: This study investigates how Europeans seek information related to healthy eating, what determines their information seeking and whether any problems are encountered in doing so.Method: A survey was administered through computer-assisted on-line web-interviewing. Respondents were grouped by age and sex (n=3003, age 16) in Belgium, Denmark, Italy, Poland, and the UK.Analysis: Descriptive statistics and regression analysis were used to analyse the influence of social, demographic, psychological and economic characteristics on the information seeking of the respondents. Results: Nearly half of those surveyed do not know where to look for information on healthy diets. Men, less well educated, poorer and sicker person know less about where to look for such information and are less likely to attempt finding it. Most of the respondents searching for information on the Internet use Google as a search tool.Conclusions: Individual and environmental factors affect information behaviour and should be taken into account in public campaigns aimed at changing eating habits of the population to increase their effectiveness. More emphasis should be placed on raising health information literacy of the information-poor, men, the uneducated, and the economically disadvantaged.
Photoreception and vision in the ultraviolet

ABSTRACT Ultraviolet (UV) light occupies the spectral range of wavelengths slightly shorter than those visible to humans. Because of its shorter wavelength, it is more energetic (and potentially more photodamaging) than ‘visible light’, and it is scattered more efficiently in air and water. Until 1990, only a few animals were recognized as being sensitive to UV light, but we now know that a great diversity, possibly even the majority, of animal species can visually detect and respond to it. Here, we discuss the history of research on biological UV photosensitivity and review current major research trends in this field. Some animals use their UV photoreceptors to control simple, innate behaviors, but most incorporate their UV receptors into their general sense of vision. They not only detect UV light but recognize it as a separate color in light fields, on natural objects or living organisms, or in signals displayed by conspecifics. UV visual pigments are based on opsins, the same family of proteins that are used to detect light in conventional photoreceptors. Despite some interesting exceptions, most animal species have a single photoreceptor class devoted to the UV. The roles of UV in vision are manifold, from guiding navigation and orientation behavior, to detecting food and potential predators, to supporting high-level tasks such as mate assessment and intraspecific communication. Our current understanding of UV vision is restricted almost entirely to two phyla: arthropods and chordates (specifically, vertebrates), so there is much comparative work to be done. Summary: Humans are blind to ultraviolet light, but most animals have a well-developed sensitivity to this very short-wavelength range. This Review focuses on how ultraviolet photoreceptors commonly contribute to high-level visual function and are used in both color and polarization vision.
The giant extracellular matrix‐binding protein of Staphylococcus epidermidis mediates biofilm accumulation and attachment to fibronectin

Virulence of nosocomial pathogen Staphylococcus epidermidis is essentially related to formation of adherent biofilms, assembled by bacterial attachment to an artificial surface and subsequent production of a matrix that mediates interbacterial adhesion. Growing evidence supports the idea that proteins are functionally involved in S. epidermidis biofilm accumulation. We found that in S. epidermidis 1585v overexpression of a 460 kDa truncated isoform of the extracellular matrix‐binding protein (Embp) is necessary for biofilm formation. Embp is a giant fibronectin‐binding protein harbouring 59 Found In Various Architectures (FIVAR) and 38 protein G‐related albumin‐binding (GA) domains. Studies using defined Embp‐positive and ‐negative S. epidermidis strains proved that Embp is sufficient and necessary for biofilm formation. Further data showed that the FIVAR domains of Embp mediate binding of S. epidermidis to solid‐phase attached fibronectin, constituting the first step of biofilm formation on conditioned surfaces. The binding site in fibronectin was assigned to the fibronectin domain type III12. Embp‐mediated biofilm formation also protected S. epidermidis from phagocytosis by macrophages. Thus, Embp is a multifunctional cell surface protein that mediates attachment to host extracellular matrix, biofilm accumulation and escape from phagocytosis, and therefore is well suited for promoting implant‐associated infections.
A role for fructose 2,6-bisphosphate in regulating carbohydrate metabolism in guard cells.

Fructose 2,6-bisphosphate (Fru2,6P(2)) appears to function as a regulator metabolite in glycolysis and gluconeogenesis in animal tissues, yeast, and the photosynthetic cells of leaves. We have investigated the role of Fru2,6P(2) in guard-cell protoplasts from Vicia faba L. and Pisum sativum L. (Argenteum mutant), and in epidermal strips purified by sonication from all cells except for the guard cells. Guard-cell protoplasts were separated into fractions enriched in cytosol and in chloroplasts by passing them through a nylon net, followed by silicone oil centrifugation. The cytosol contained a pyrophosphate: fructose 6-phosphate phosphotransferase (involved in glycolysis) which was strongly stimulated by Fru2,6P(2). A cytosolic fructose 1,6-bisphosphatase (a catalyst of gluconeogenesis) was inhibited by Fru2,6P(2). There was virtually no fructose 1,6-bisphosphatase activity in guard-cell chloroplasts of V. faba. It is therefore unlikely that the starch formed in these chloroplasts originates from imported triose phosphates or phosphoglycerate.The level of Fru2,6P(2) in guard-cell protoplasts and epidermal strips was about 0.1 to 1 attomole per guard cell in the dark (corresponding to 0.05 to 0.5 nanomole per milligram chlorophyll) and increased three- to tenfold within 15 minutes in the light. Within the same time span, hexose phosphate levels in guard-cell protoplasts declined to approximately one-half, indicating that acceleration of glycolysis involved stimulation of reactions using hexose phosphates. The level of Fru2,6P(2) in guard cells appears to determine the direction in which carbohydrate metabolism proceeds.
A hierarchical genetic algorithm based approach for image segmentation

Image segmentation denotes a process by which an image is partitioned into non-intersecting regions and each region is homogeneous. Many approaches have been proposed for the monochrome image segmentation. Among these approaches, the clustering methods have been extensively investigated and used. In this paper, a clustering based approach using hierarchical genetic algorithm is proposed to tackle the problem of image segmentation. The main advantage of the proposed approach is that it can simultaneously estimate a proper number of regions and then partition the image into several homogeneous regions. The simulation results indicate that the proposed approach can produce more continuous and smoother images in comparison with two existing methods.
Aerobic program in persons with stroke: a systematic review.

INTRODUCTION The aim of this study was to perform a systematic review on the exercise trials post stroke. MATERIAL AND METHODS Therefore, we conducted a systematic review of randomized controlled clinical trials published in PubMed and PEDro. The inclusion criteria were: Studies--randomized or controlled clinical trials; Participants--adults of any age with a clinical diagnosis of stroke; Interventions--any aerobic physical training aimed at improving cardiovascular capacity and/or function. Two independent reviewers categorized the selected trials, assessed methodological quality and extracted the relevant data. Various protocols were analyzed and used for both the assessment and physical training of post-stroke subjects. RESULTS According to clinical trials analyze, a wide range of instruments were used to measure functional capacity. Ergospirometry and ergometry were found to be main devices in the assessment of cardiovascular capacity. Cycle ergometer training was the most commonly used training strategy, and conventional physiotherapy (based on stretching, strengthening, balance, coordination and gait training) was the most frequent control therapy. DISCUSSION Training duration ranged from 4 weeks to 6 months; the mean weekly frequency was 3 sessions per week while training intensity ranged from 40 to 80% of maximal heart rate or VO2 peak. Duration of training sessions ranged from 25 minutes to 1 hour. CONCLUSION Exercise training is a promising tool for the management of post-stroke patients, both in terms of improved cardiovascular and functional capacity. Further studies are needed to widen the scope of therapeutic management of this population.
Dual-Space Vector Control of Open-End Winding Permanent Magnet Synchronous Motor Drive Fed by Dual Inverter

This paper proposes a dual-space vector control scheme for the open-end winding permanent magnet synchronous motor (OEW-PMSM) drive fed by the dual inverter with a single dc supply. Potential zero-sequence current in the open-end winding drive system has to be considered since it causes circulating current in the winding and leads to high current stress of power semiconductor devices and high losses. Zero-sequence current in open-end winding ac motor drives is usually caused by the zero-sequence voltage, and therefore switching combinations which do not produce zero-sequence voltage are used to synthesize the reference voltage in existing methods. But even so, the zero-sequence voltage can also be produced by the dead time of the inverter. In order to suppress zero-sequence current in the OEW-PMSM drive, a dual-space vector control scheme is proposed and a novel dual-inverter space vector pulse width modulation (PWM) with the zero-sequence voltage reference is employed to regulate system zero-sequence voltage in this paper. Compared with existing dual inverter PWM strategies, the novel algorithm build a regulation mechanism for the zero-sequence voltage. The proposed method is compared with the conventional vector control by simulations and experiments, and the results shown that the proposed scheme can suppress zero-sequence current effectively.