Miracle-dz/UniFAR-FTUs huggingface dataset:
Shift work. Shift-dependent well-being and individual differences.

The present study was designed to describe sleep length and subjective ratings of sleep quality for workers on different shifts in a three-shift system, and to relate inter-individual differences to possible causative factors. 390 workers on three-shift, two-shift and day work systems filled out a questionnaire on work hours and well-being. For three-shift workers sleep quality was best and sleep length longest when the subjects were on the afternoon shift, followed by the morning shift, and then the night shift. Two-shift workers gave ratings almost identical to those of the three-shift workers on corresponding shifts. With increasing age and experience of shift work, sleep quality and sleep length were reduced. Diurnal type was highly correlated with age. Background variables like marital status, number of children and housing conditions did not have any predictive power, and neither had neuroticism or extroversion. Above the age of 45, sleep quality and sleep length in connection with the night shift d.
Evaluation of single sample clearance calculations in 902 patients

Purpose: To derive new formulae for the calculation of single sample clearance of the contrast medium iohexol and to compare the formulae to a selection of existing single sample clearance formulae derived for the calculation of 51Cr-EDTA and 99mTc-DTPA clearance. Material and Methods: Glomerular filtration rate (GFR) was calculated from total plasma clearance of iohexol used for urography in 902 patients. Two plasma samples were drawn in each patient. Automated x-ray fluorescence analysis equipment was used for the plasma iodine analysis. Single and multiple sample iohexol clearance values were compared. In 77 patients the multiple sample clearance values were additionally compared to a 51Cr-EDTA clearance performed simultaneously or within 14 days. Results: The precision of the results calculated by the existing single sample clearance formulae and the derived iohexol single sample clearance formulae were essentially the same. The most precise of the derived formulae was that based on the Bak Christensen & Groth formula. The correlation between multiple sample clearance of iohexol and 51Cr-EDTA was high (r=0.918) Conclusion: Iohexol can substitute 51Cr-EDTA for GFR measurement. A valid GFR can be calculated from a single plasma sample determination of iohexol clearance using either the existing formulae or the new formulae derived from the present study.
Corporate finance theory

1. The Role of Financial Theory and Evidence. 2. Ownership, Control, and Compensation. 3. Risk, Return, and Market Efficiency. 4. Bond and Stock Valuation. 5. Option Valuation. 6. Capital Budgeting and Investment Decisions. 7. Capital Structure Theory. 8. Dividend Policy. 9. Understanding and Accessing Financial Markets.
Pattern and profile of electric burn injury cases at a Burn centre.

BACKGROUND Electrical burns are quite different from thermal and chemical burns. This study is from a centre which deals with job related electric burn injuries alone and thus can give a pure account of the electric burns and discuss the related peculiarities. Study aims to highlight the differences in the mechanism of electric burn injury, its mode of presentation, morbidity, complications and thus the treatment strategies as compared to rest of the burn injuries. METHODS This is a descriptive case series study of first consecutive 61 electric burn victims treated at a Burn Unit and Plastic Surgery centre. Cases were admitted and resuscitated at the emergency, and further treated at burn unit. Thorough history, examination findings and operative procedures were recorded. Patients were photographed for record as well. Emergency operative procedures, wound management, soft tissue coverage procedures and complications during the hospital stay were recorded and studied. RESULTS Twenty cases (33%) were in the fifth decade of life. High voltage electric burn injury was seen in 42 (69%) of the cases. Whereas only 9 cases were treated conservatively, other 52 cases had 24 fasciotomies and 71 debridements. Series witnessed 10 expiries, and 22 amputations and all these were result of high voltage electric burns. Twenty eight soft tissue coverage procedures were carried out. CONCLUSIONS Electric burn injuries are altogether different from rest of the burn injuries and must be treated accordingly. These injuries are peculiar for ongoing damage, extensive trauma, complications and prolonged morbidity. Treatment requires a high degree of suspicion, more aggressive management to unfold and minimize the deep seated insult.
Trial of labour after a previous caesarean section delivery: a private hospital experience.

In an attempt to reduce the rising trend of caesarean deliver worldwide obstetrician now offer trial of labour more readily to women who have had a caesarean section. Although trial of labour is usually successful and safe it may occasionally be associated with severe morbidity and even mortality. In this report we audited all cases of trial of labour after a previous caesarean delivery in our hospital. A three year (2000 - 2003) prospective study of all cases of trial of labour after one previous caesarean section at the Havana Specialist Hospital Lagos. Of the 1481 deliveries in our hospital during the period 179 (11.9%) had previously been delivered through caesarean section. While 29.3% (51) of the women with previous caesarean delivery had elective caesarean section 70.7% (123) were allowed trial of labour. Eighty-five (69.1%) women had successful trial of labour. The failure rate was thus 30.9%. Cephalopelvic disproportion and slow progress of labour was the main cause of failure. Majority (58.8%) of the patients that achieved vaginal delivery needed assistance in the form of vacuum delivery (40.0%) vacuum delivery & episiotomy (30.0%) episiotomy alone (28.0%) and forceps deliver (2.0%). When fetal and maternal outcome were compared between emergency and elective caesarean section it was only in Apgar score at 1 minute was there significant difference. One (0.8%) uterine rupture occurred because of delayed consent and she was not among the eight patients that had oxytocin augmentation of labour. In countries where caesarean section are not readily acceptable flexibility within the frame work of good obstetric practice is the desired goal. However labour in women with scarred uterus must be conducted in institution that have facilities for emergency obstetric services. This study has shown that trial of labour in patient with one previous caesarean section is not only feasible but practicable and oxytocin augmentation is safe when judiciously used. (authors)
The Relationship among Leadership style, Perceived Organizational Support, and Employees’ Job Performance in Iran Khodro Dissel Company

Abstract. The present study aimed to examine the relationship between leadership style and employees’ job performance in Iran Khodro Dissel Company. In so doing, the role of the moderating variable of perceived organizational support has been evaluated with regard to the relationship between leadership style and employees’ job performance. The method was applied in terms of the objective and correlational-descriptive in terms of method and nature. Accordingly, the study population was composed of all employees in Iran Khodro Dissel Company with at least bachelor degree that using Cochran formula, 261 subjects were selected as the study sample through simple random sampling technique. For data collection, the standard questionnaires of Bass and Olive (1994) Multi - factor Leadership Questionnaire (MLQ) including transformational and transactional leadership styles, LaMastro (1999) perceived organizational support of employees and Paterson (1998) job performance were used. The collected data were analyzed using Lisrel and SPSS19 software. The results obtained from the study revealed that there is a significant relationship between leadership style and employee’s job performance in Iran Khodro Dissel Company. In addition, the results showed a significant relationship between perceived organizational support and job performance, transformational leadership style with perceived organizational support and job performance, and transactional leadership style with perceived organizational support and job performance. Also, the results of regression analysis approved the impact of moderating variable of perceived organizational support on the relationship between perceived leadership style and employees’ job performance in Iran Khodro Dissel Company.
Synapsis of loxP Sites by Cre Recombinase*

Cre recombinase catalyzes site-specific recombination between 34-bp loxP sites in a variety of topological and cellular contexts. An obligatory step in the recombination reaction is the association, or synapsis, of Cre-bound loxP sites to form a tetrameric protein assembly that is competent for strand exchange. Using analytical ultracentrifugation and electrophoresis approaches, we have studied the energetics of Cre-mediated synapsis of loxP sites. We found that synapsis occurs with a high affinity (Kd = 10 nm) and is pH-dependent but does not require divalent cations. Surprisingly, the catalytically inactive Cre K201A mutant is fully competent for synapsis of loxP sites, yet the inactive Y324F and R173K mutants are defective for synapsis. These findings have allowed us to determine the first crystal structures of a pre-cleavage Cre-loxP synaptic complex in a configuration representing the starting point in the recombination pathway. When combined with a quantitative analysis of synapsis using loxP mutants, the structures explain how the central 8 bp of the loxP site are able to dictate the order of strand exchange in the Cre system.
Allatostatin‐like‐immunoreactive neurons of the tobacco hornworm, Manduca sexta, and isolation and identification of a new neuropeptide related to cockroach allatostatins

The YXFGLamide C‐terminus serves to define most members of a family of structurally related neuropeptides, the YXFGLamides. These peptides have been identified from the nervous system of various insects and include the allatostatins of cockroaches and crickets, the schistostatins of locusts, and the callatostatins of blowflies. The YXFGLamides have been shown to have various functions, including inhibition of juvenile hormone biosynthesis in cockroaches and crickets and inhibition of contraction of certain insect visceral muscles. We wanted to know if these peptides occur in Manduca sexta and what functions they might have. A new peptide, AKSYNFGLamide, was isolated and identified from M. sexta and has been named “lepidostatin‐1”; this is the first YXFGLamide to be found in a lepidopteran, and there are indications that additional YXFGLamides occur in M. sexta. An antiserum to cockroach allatostatins (YXFGLamides) was shown to recognize lepidostatin‐1 of M. sexta and was used to map YXFGLamide‐immunoreactive neurons in larvae. Because immunoreactive interneurons were found to form an extensive neuropil, YXFGLamides probably function as neuromodulators in M. sexta. Neuroendocrine cells in the brain, abdominal ganglia, and their respective neurohemal organs were YXFGLamide immunoreactive and appear to release YXFGLamides as neurohormones. Immunoreactivity to YXFGLamides and M. sexta diuretic hormone were found to be colocalized and appear to be coreleased in these neuroendocrine cells, indicating that YXFGLamides may be involved in regulation of fluid transport. Innervation of the corpora allata by YXFGLamide‐immunoreactive processes was very sparse, suggesting that this innervation does not play an important role in allatostasis. Many thoracic motor neurons were YXFGLamide immunoreactive, suggesting that YXFGLamides may have a myomodulatory or myotrophic function in larvae. However, this immunoreactivity disappeared early in metamorphosis and did not reappear in the adult. The YXFGLamide‐immunoreactive neurons in the terminal abdominal ganglion were found to innervate the hindgut, indicating that YXFGLamides may be involved in the control of the rate of myogenic contractions of the larval hindgut. J. Comp. Neurol. 385:265–284, 1997. © 1997 Wiley‐Liss, Inc.
Service-dominant logic for managing the logistics-manufacturing interface: A case study

Purpose: The purpose of this paper is to investigate the management of the logistics-manufacturing interface between the manufacturer and its logistics service provider from the perspective of the service-dominant (S-D) logic. Design/methodology/approach: The approach adopted is that of abductive reasoning through case study: data is primarily gleaned from semi-structured in-depth interviews. Field visits and secondary documentation are used to ensure data validity. Findings: The results show that the interface can be categorized into three levels: design interface between products and logistic services, process interface between manufacturing processes and service-offering processes, and information interface between manufacturing information systems and logistics information systems. The results also indicate that ten foundational premises of S-D logic, especially service-focused, customer-oriented, and rational views can be applied in defining and managing these interfaces. Research limitations/implications: This research contributes not only to the theory of S-D logic and managing interface, but also provides managers with guidelines of applying S-D logic to build a service-focused, customer-oriented and relational logic to effectively manage the logistics-manufacturing interface. However, the research is limited to the context of automotive and logistics industries. Originality/value: Three levels of logistics-manufacturing interface, including design, process and information are identified, and S-D logic is applied to identify and manage the interface.
Acute effects of short‐chain alkylglycerols on blood‐brain barrier properties of cultured brain endothelial cells

The blood‐brain barrier (BBB) restricts drug penetration to the brain preventing effective treatment of patients suffering from brain tumours. Intra‐arterial injection of short‐chain alkylglycerols (AGs) opens the BBB and increases delivery of molecules to rodent brain parenchyma in vivo. The mechanism underlying AG‐mediated modification of BBB permeability is still unknown. Here, we have tested the effects of AGs on barrier properties of cultured brain microvascular endothelial cells.
Generalized periodic rings.

Let R be a ring, and let N and C denote the set of nilpotents and the center of R, respectively. R is called generalized periodic if for every x∈R\(N⋃C), there exist distinct positive integers m, n of opposite parity such that xn−xm∈N⋂C. We prove that a generalized periodic ring always has the set N of nilpotents forming an ideal in R. We also consider some conditions which imply the commutativity of a generalized periodic ring.
Potential For Off-Peak Freight Deliveries To Commercial Areas: Implementation Plan

As discussed throughout the project (Holguin-Veras 2006), the implementation of off-peak deliveries (OPD) requires both receivers that are willing to accept deliveries during the off-peak hours, as well as carriers willing to provide the service. The project highlighted that receivers, by virtue of being the end customer, have a great deal of influence on what the carriers do. In this context, should a significant number of receivers decide to request off-peak deliveries, it is almost certain that the carriers would follow suit. This fact has important implications becauseshort of mandatory regulations forcing the private sector to do off-peak deliveries-it is clear that the long-term sustainability of off-peak delivery programs require policy incentives to mitigate the impacts on receivers, which are likely to face additional costs. On the other hand, carriers-that stand to benefit from the increased productivity derived from faster travel speeds during the off-peak hours-are likely to participate in off-peak deliveries if sufficient number of receivers request the service. These concepts are to be kept in mind throughout this section. This report focuses on the implementation of off-peak delivery policies.
Effects of Dividends on Common Stock Prices: The Nepalese Evidence

This paper attempts to explain the effect of dividend payment and retained earnings on market price of share in the context of Nepalese companies. A majority of earlier studies conducted in USA mostly indicate that retained earning effect is more than the dividend effect given investment opportunities. A study of Indian evidence shows that their stock market has also started recognizing the impact of retained earnings. This paper investigates these implications in the context of Nepal and finds only limited support for it. The results indicate the customary strong dividend and very weak retained earnings effect on market price of share. The study shows a predominant influence of dividends and an absence of retained earning effect on share price. Dividends are found relatively more attractive among the Nepalese stockholders. They are therefore not indifferent toward dividend and retained earnings.
Transformation by vSrc vSrc vSrc : RasMAPK RasMAPK RasMAPK and PI 3 KmTOR KmTOR KmTOR Mediate Parallel Pathways

An increase in the level of active, GTP-bound Ras is not necessary for transformation of chicken embryo fibroblasts (CEF) by v-Src. This suggests that other Ras-independent pathways contribute to transformation by v-Src. To address the possibility that activation of phosphatidylinositol-3-kinase (PI3K) and the mammalian target of rapamycin (mTOR/FRAP), represents one of these pathways, we have examined the effect of simultaneous inhibition of the Ras-MAPK and PI3K-mTOR pathways on transformation of CEF by v-Src. Transformation was assessed by the standard parameters of morphological alteration, increased hexose uptake, loss of density inhibition, and anchorageindependent growth. Inhibition of the Ras-MAPK pathway by expression of the dominant-negative Ras mutant HRasN17 or by addition of the MAPK kinase (MEK) inhibitor PD98059 reduced several of these parameters but failed to block transformation. Similarly, inhibition of the PI3K-mTOR pathway by addition of the PI3K inhibitor 2-[4morpholinyl]-8-phenyl-4H-1-benzopyran-4-one (LY294002) or the mTOR inhibitor rapamycin, although reducing several parameters of transformation, also failed to block transformation. However, simultaneous inhibition of signaling by the Ras-MAPK pathway and the PI3K-mTOR pathway essentially blocked transformation. These data indicate that transformation of CEF by v-Src is mediated by two parallel pathways, the Ras-MAPK pathway and the PI-3K-mTOR pathway, which both contribute to transformation. The possibility that simultaneous activation of other pathways is also required is not excluded.
Induction of pre-ovulatory gonadotrophin surge with gonadotrophin-releasing hormone agonist compared to pre-ovulatory injection of human chorionic gonadotrophins for ovulation induction in intrauterine insemination treatment cycles.

The clinical outcome of intrauterine insemination (IUI) treatment cycles employing a gonadotrophin-releasing hormone agonist [GnRHa, triptorelin (Decapeptyl)] or human chorionic gonadotrophin (HCG) for ovulation induction was compared. A group of 48 patients presenting with amenorrhoea, oligomenorrhoea or unexplained infertility were all treated with human menopausal gonadotrophins (HMG) from day 5 of the cycle, on an individualized schedule. They were then randomly divided into two groups to receive either a single s.c. injection of 0.1 mg triptorelin or a single i.m. injection of 10,000 IU HCG after follicular maturation. IUI was performed approximately 24 and 48 h following the injection. A transitory increase in serum luteinizing hormone and follicle stimulating hormone concentrations was achieved following injection of GnRHa. A total of 24 patients received 72 treatment cycles with GnRHa, producing 11 conceptions (15.3%) and two abortions (18.2%), resulting in a term pregnancy rate of 13.6%. There were four cases of grade 3-4 ovarian hyperstimulation syndrome (OHSS), two of which were conception cycles. In all, 24 patients underwent 68 cycles treated with HCG, producing 18 conceptions (26.5%) and six abortions (33.3%), resulting in a term pregnancy rate of 19.0%. There were eight cycles of grade 3-4 OHSS, two of which were conception cycles. These results show that an s.c. injection of a relatively low dose of GnRHa can be as effective as HCG in producing pregnancy in IUI treatment cycles.
The effect of power distance and individualism on service quality expectations in banking

Purpose – The purpose of this paper is to investigate the relationship between Canadian and Indian consumers' national cultural orientations and banking service quality expectations. Using two of Hofstede's five cultural dimensions operationalized at the individual level, and five dimensions of service quality from Parasuraman et al.'s SERVQUAL scale, the aim is to develop and test hypotheses relating national culture values to service quality expectations.Design/methodology/approach – The study is quantitative in nature, using surveys (online and written) from respondents in Canada and India. Data were analyzed using dummy variable regression and structural equation modeling.Findings – The results show that the importance of various SERVQUAL dimensions is related to Hofstede's power distance and individualism cultural dimensions both at the individual and national levels. More specifically, consumers low on power distance expect highly responsive and reliable service. High power distance customers attach.
Comparison of visual inspection of cervix and Pap smear for cervical cancer screening.

OBJECTIVE To evaluate the performance of visual inspection of cervix (VIA) after application of 3% acetic acid in cervical cancer screening in comparison with Pap smear. DESIGN Comparative study. PLACE AND DURATION OF STUDY This study was conducted at Sir Ganga Ram hospital, Lahore, from January 1996-December 1999. SUBJECTS AND METHODS Speculum examination was carried out to see the cervix in 501 women. All subjects were screened simultaneously by Pap smear and VIA after application of 3% acetic acid. Positive cases by both screening methods and grossly abnormal cervix even with negative screen were subjected to colposcopy. In case of colposcopic abnormality of atypia or advanced lesions, biopsies were taken. Histology of colposcopically directed biopsy was taken as gold standard to evaluate the performance of the test. RESULTS Out of 540 subjects, 356 were negative with both screening techniques. One hundred and fifty-six subjects were positive with VIA(28.9%) while Pap smear was positive in seventy-eight subjects (14.4%). The sensitivity of VIA was 93.9% and of Pap smear was 46.9%. Corresponding specificities were 30.4% and 69.5%. There was no significant difference between the positive predictive value (PPV) of both test (p < 0.05). The accuracy of VIA was 77.5% compared to 52.8% of Pap smear. The difference was highly significant (p < 0.01). CONCLUSION These results indicate that VIA is more sensitive and has a higher accuracy as compared to Pap smear. It could, therefore, be valuable in detection of precancerous lesions of cervix. Low cost, easy applicability and immediate results make VIA a useful screening test in developing countries like Pakistan as compared to Pap smear.
Pricing Initial Public Offerings on 'New' European Stock Markets

In 2000 more companies listed in Europe than in the US. This is mainly due to the success of "new" stock markets designed for high-growth companies. In this paper we analyse a sample of 482 Initial Public Offerings (IPOs), listed on five "new" European stock markets up to March 2001. We investigate the determinants of their first-day returns. We find a mean first-day return (underpricing) equal to +38.09%. Market returns, the IPO firm's risk and price revisions in the premarket are positively related to first-day returns, whereas IPO deal flow shows is inversely related to underpricing. We also show that the Internet euphoria impacts first-day returns.