Miracle-dz/UniFAR-FTUs huggingface dataset:
Development of bio-inspired underwater robot with adaptive morphology capable of multiple swimming modes

Bio-inspired underwater robots have several benefits compared to traditional underwater vehicles such as agility, efficiency, and environmentally friendly body. However, bio-inspired underwater robots developed so far have a single swimming mode, which may limit their capability to perform different tasks. This paper presents a re-configurable bio-inspired underwater robot that can change the morphology to enable multiple swimming modes: octopus-mode and fish-mode. The robot is 60 cm long and 50 cm wide, weighing 2.1 kg, and consists of a re-configurable body and 8 compliant arms that are actuated independently by waterproof servomotors. In the robot, the octopus-mode is expected to perform unique tasks such as object manipulation and ground locomotion as demonstrated in literature, while the fish-mode is promising to swim faster and efficiently to travel long distance. With this platform, we investigate the effectiveness of adaptive morphology in bio-inspired underwater robots. For this purpose, we evaluated the robot in terms of the cost of transport and the swimming efficiency of both the morphologies. The fish-mode exhibited a lower cost of transport of 2.2 and higher efficiency of 1.2 % compared to the octopus-mode, illustrating the effect of the multiple swimming modes by adaptive morphology.
Transoral Laser Microsurgery for Malignancies of the Upper Aerodigestive Tract

Transoral laser microsurgery (TLM) is an important option in the treatment plan for tumors of the oral cavity, oropharynx, larynx, and hypopharynx. For properly selected patients, TLM provides equivalent oncologic outcomes when compared to traditional therapies, while improving the functional aspects of postoperative speech, voice and swallowing.
Evolution of the amygdaloid complex in vertebrates, with special reference to the anamnio‐amniotic transition

Numerous studies over the last few years have demonstrated that the amygdaloid complex in amniotes shares basic developmental, hodological and neurochemical features. Furthermore, homologous territories of all the main amygdaloid subdivisions have been recognized among amniotes, primarily highlighted by the common expression patterns for numerous developmental genes. Thus, derivatives from the lateral pallium, ventral pallium and subpallium constitute the fundamental parts of the amygdaloid complex. With the development of new technical approaches, study of the precise neuroanatomy of the telencephalon of the anuran amphibians (anamniotes) has been possible. Current embryological, hodological and immunohistochemical evidence strongly suggests that most of the structures present in amniotes are recognizable in these anamniotes. These investigations have yielded enough results to support the notion that the organization of the anuran amygdaloid complex includes subdivisions with their origin in ventral pallial and subpallial territories; a strong relationship with the vomeronasal and olfactory systems; abundant intra‐amygdaloid connections; a main output centre involved in the autonomic system; recognizable amygdaloid fibre systems; and distinct chemoarchitecture. Therefore, the new ideas regarding the amygdaloid evolution based on the recent findings in anamniotes, and especially in anurans, strongly support the notion that basic amygdaloid structures were present at least in the brain of ancestral tetrapods organized following a basic plan shared by tetrapods.
Ultrastructure of the bullfrog (Lithobates catesbeianus‐Shaw, 1802) oviduct in different seasons

The bullfrog (Lithobates catesbeianus) is an exotic animal that adapted perfectly to the climatic conditions of Brazil after introduction in the country. These climatic conditions favor the reproduction and fattening of bullfrogs. However, the development of the bullfrog is significantly reduced in colder regions because low temperatures affect the secretion of gonadotropins and change the sensitivity of the germinal epithelium to gonadotropic hormones. Thus, the temperature and photoperiod are abiotic factors that influence the life cycle of this species, especially with regard to reproduction. Samples from different regions of the oviducts (the infundibulum, magnum, and isthmus) of 9 bullfrogs were collected in the different seasons of the year. The samples were fixed and processed for analysis with scanning and transmission electron microscopy. A comparison of the morphology of the oviducts collected during different seasonal periods suggests that the frogs have greater reproductive potential in the spring due to the development of the structures related to the oviduct, presence of developed cilia, and electron‐dense granules. However, seasonal changes were noted in the animal throughout the year in preparation for reproduction during the spring and summer. Microsc. Res. Tech. 76:523–532, 2013. © 2013 Wiley Periodicals, Inc.
Liver Sinusoidal Endothelial Cells Are a Site of Murine Cytomegalovirus Latency and Reactivation

ABSTRACT Latent cytomegalovirus (CMV) is frequently transmitted by organ transplantation, and its reactivation under conditions of immunosuppressive prophylaxis against graft rejection by host-versus-graft disease bears a risk of graft failure due to viral pathogenesis. CMV is the most common cause of infection following liver transplantation. Although hematopoietic cells of the myeloid lineage are a recognized source of latent CMV, the cellular sites of latency in the liver are not comprehensively typed. Here we have used the BALB/c mouse model of murine CMV infection to identify latently infected hepatic cell types. We performed sex-mismatched bone marrow transplantation with male donors and female recipients to generate latently infected sex chromosome chimeras, allowing us to distinguish between Y-chromosome (gene sry or tdy)-positive donor-derived hematopoietic descendants and Y-chromosome-negative cells of recipients' tissues. The viral genome was found to localize primarily to sry-negative CD11b− CD11c− CD31+ CD146+ cells lacking major histocompatibility complex class II antigen (MHC-II) but expressing murine L-SIGN. This cell surface phenotype is typical of liver sinusoidal endothelial cells (LSECs). Notably, sry-positive CD146+ cells were distinguished by the expression of MHC-II and did not harbor latent viral DNA. In this model, the frequency of latently infected cells was found to be 1 to 2 per 104 LSECs, with an average copy number of 9 (range, 4 to 17) viral genomes. Ex vivo-isolated, latently infected LSECs expressed the viral genes m123/ie1 and M122/ie3 but not M112-M113/e1, M55/gB, or M86/MCP. Importantly, in an LSEC transfer model, infectious virus reactivated from recipients' tissue explants with an incidence of one reactivation per 1,000 viral-genome-carrying LSECs. These findings identified LSECs as the main cellular site of murine CMV latency and reactivation in the liver.
Tick Sizes in Illiquid Order Books

I assess the causal impact of increasing the tick size on stock liquidity and trading volume in illiquid stocks. Using a regression discontinuity design at the Oslo Stock Exchange, I find that increasing the tick size has no impact on the transaction costs,order book depths, or trading volumes of illiquid stocks. These findings contradict recent theoretical predictions in the market microstructure literature as well as proposals by lawmakers in the United States to increase the tick size for illiquid stocks.
Public Pressure and Corporate Tax Behavior

We use a shock to the public scrutiny of firm subsidiary locations to investigate whether that scrutiny leads to changes in firms’ disclosure and corporate tax avoidance behavior. ActionAid International, a nonprofit activist group, levied public pressure on noncompliant U.K. firms in the FTSE 100 to comply with a rule requiring U.K. firms to disclose the location of all of their subsidiaries. We use this setting to examine whether the public pressure led scrutinized firms to increase their subsidiary disclosure, decrease tax avoidance, and reduce the use of subsidiaries in tax haven countries compared to other firms in the FTSE 100 not affected by the public pressure. The evidence suggests that the public scrutiny sufficiently changed the costs and benefits of tax avoidance such that tax expense increased for scrutinized firms. The results suggest that public pressure from outside activist groups can exert a significant influence on the behavior of large, publicly traded firms. Our findings extend prior research that has had little success documenting an empirical relation between public scrutiny of tax avoidance and firm behavior.
Stability of the metatarsophalangeal joint of the lesser toes: A cadaveric study

Dorsal instability of the metatarsophalangeal joint (MTPJ) of the lesser toes is an important cause of forefoot pain. Both conservative and surgical treatment options have been proposed. However, the role of each static stabilizing structure has not been elucidated. We hypothesized that isolated sectioning of the plantar plate (PP) would result in greater dorsal translation compared to isolated sectioning of the medial collateral ligaments (MCL) or lateral (LCL) collateral ligaments, or the extensor hood (EH), and that combined injury to two or more structures would result in greater dorsal translation compared to isolated PP injury. Fifty‐four cadaveric lesser toe specimens were randomized into groups for individual and combined sectioning of the PP, EH, and LCL and MCL. A 30 N axial load was applied to each specimen in the plantar–dorsal direction and dorsal translation of the phalanx was measured for each condition. ANOVA was used to compare groups. A 19% change in MTP translation was found from intact after sectioning the PP. No significant difference in translation was seen after individual sectioning of the EH, MCL, or LCL. A significant increase in translation occurred from intact with the following sectioning combinations: MCL + LCL, 37%; EH + MCL + LCL, 45%; and PP + MCL + LCL, 63%. Thus, the PP is the main restraint for dorsal MTPJ translation. MCL and LCL have important partial contribution to MTPJ stability. Injury to the PP, individually, or combined injuries to the PP, EH, MCL, or LCL, appear to cause significant instability that may warrant more aggressive treatment. © 2012 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 30:1995–1998, 2012
Effect of dietary dilution of energy and nutrients during different growing periods on compensatory growth of Ross broilers

A completely randomized design was conducted to evaluate the effect of dietary dilution of energy and nutrients during different growing periods on compensatory growth of Ross broilers. Four replicant pens were assigned per seven treatments. Chicks in each treatment received concentrated and diluted diets in different stages of growing periods (starter, grower and finisher). The diets were mainly based on maize and soybean meal and had constant ratio of metabolizable energy/nutrients. It was concluded that feed intake, feed conversion, production index, feed cost and metabolizable energy per weight gain of chicks receiving concentrated diets during all stages of growing periods were the same as the chicks receiving diluted diets during finisher period (P > 0.05). The amount of abdominal fat was significantly lower in chicks receiving diluted diets during finisher period (P ≤ 0.05). Mortality percentage in chicks receiving concentrated diets during all stages of growing periods was significantly more than other treatments (P ≤ 0.05). Based on the results of the experiment, diluted diets for finisher period of Ross broilers male chicks is suggested.
Pneumocystis jirovecii colonization among renal transplant recipients

Renal transplant recipients are at risk of developing Pneumocystis pneumonia (PcP), especially in the first 2 years after transplantation, with a mortality rate of up to 50%. No data are available on pulmonary colonization with Pneumocystis jirovecii in renal transplant recipients. The aim of this study was to determine the prevalence of pulmonary colonization with Pneumocystis jirovecii in renal transplant recipients and to find related risk factors.
31P NMR characterization of graded traumatic brain injury in rats

Irreversible tissue injury following central nervous system trauma is believed to result from both mechanical disruption at the time of primary insult, and more delayed “autodestructive” processes. These delayed events are associated with various biochemical changes, including alterations in phosphate energy metabolism and intracellular pH. Using 31P NMR, we have monitored the changes in phosphorus energy metabolism and intracellular pH in a single hemisphere of the rat brain over an 8‐h period following graded, traumatic, fluid percussion‐induced brain injury. Following trauma the ratio of phosphocreatine to inorganic phosphate (PCr/Pi) declined in each injury group. This decline was transitory with low injury (1.0 ± 0.5 atm), biphasic with moderate (2.1 ± 0.4 atm) and high (3.9 ± 0.9 atm) injury, and sustained following severe injury (5.9 ± 0.7 atm). The initial PCr/Pi decline in the moderate and high injury groups was associated with intracellular acidosis; however, the second decline occurred in the absence of any pH changes. Alterations in ATP occurred only in severely injured animals and such changes were associated with marked acidosis and 100% mortality rate. After 4 h, the posttraumatic PCr/Pi ratio correlated linearly with the severity of injury. We suggest that a reduced posttraumatic PCr/Pi ratio may be indicative of altered mitochondrial energy production and may predict a reduced capacity of the cell to recover from traumatic injury. © 1988 Academic Press, Inc.
Influence of voluntary coffee certifications on cooperatives’ advisory services and agricultural practices of smallholder farmers in Costa Rica

ABSTRACT Purpose: This article explores how voluntary certifications influence the way cooperatives provide advisory services to their members and the influence of these services on agricultural practices. Design/Methodology/Approach: Case studies were conducted in four representative Costa Rican cooperatives interviewing twenty interviewed cooperative administrators and members to determine changes in advisory services and farming practices over the past twenty years and factors which influenced those changes. Findings: Certifications induce cooperatives to offer new services to support farmers. Cooperatives form collaborations with new stakeholders or reconfigure existing collaborations to provide advisory services to their members. These services have helped to shape farmers’ attitudes about sustainable farming practices, though farm-level changes may be small. The main change at the cooperative level is adding new topics for group training, and certification issues are directly linked with practices such as maintaining a farm record book or wearing a mask when applying pesticides. Practices which compete with productivity are unlikely to change. Practical Implications: The results are useful to improve the advisory services provided by cooperatives by better identifying the key issues to be addressed to fulfill the certifications’ requirements. Theoretical implications: Cooperatives are a relevant player to induce more sustainable practices, by providing or coordinating advisory services, but their efforts cannot be seen disconnected from a broader institutional environment. Originality/Value: We demonstrate that certifications change the intensity and scope of advisory services and induce cooperatives to engage with a more diverse network of stakeholders.
Impact physics model and influencing factors of gouging for electromagnetic rail launcher

Gouging is a damage mechanism that occurs on the surface of rails of electromagnetic railgun. The disadvantages of gouging include lowering efficiency of railgun system, decreasing life of rails and reducing direction accuracy of projectile. According to configuration and dimension of the experimental arrangement, analysis of rail vibration induced by hypervelocity sliding load and numerical solve of the dynamic response for rails have been accomplished. Based on numerical solve of the dynamic response for rails under hypervelocity sliding load, a gouging physics model of impact has been established in this paper, and gouging on the rail was successfully replicated in LS-DYNA. Through dynamic simulating, effect rule of influencing factors such as deflection bulge size on the formation of gouging and key phenomenon of gouge process were investigated. The results suggested that the obvious gouging would be avoided by lowering the maximal local deflection size in 0.5mm; the structure of smooth on the head of the armature and decrease of contact pressure between armature and rails can be utilized to alleviate the damage; during gouging process, maximal strain-rate of rail material could reach to 107s-1 while the contact area and velocity of armature would fell greatly. This work would be a foundation of future effort of avoiding rail gouging during the launch duration.
Ratio of Positive to Total Number of Sentinel Nodes Predicts Nonsentinel Node Status in Breast Cancer Patients

Abstract: Selective sentinel lymphadenectomy (SSL) has replaced axillary lymph node dissection (ALND) for many patients with early breast cancer and negative sentinel lymph nodes (SLNs). Yet many patients with a positive SLN are undergoing unnecessary ALND, as no further disease is found in the axilla. The aim of our study was to determine factors associated with additional positive lymph nodes in the axilla in patients who have a positive SLN. This was a retrospective study of patients undergoing SSL with ALND as part of their treatment for breast cancer at a single institution from November 1997 to August 2003. Only patients with one or more positive SLNs were selected for this study. There were 86 patients who fit our study criteria. Of these, 38% had further positive lymph nodes upon ALND. More than one positive SLN and a ratio of positive SLNs to total SLNs of greater than 0.5 were found to be predictors for additional axillary nodal involvement in both univariate and multivariate analyses. The number of positive SLNs and the ratio of positive SLNs to total SLNs is an indication of total tumor burden in the sentinel nodes and may be a reflection of the propensity of the tumor for further lymphatic invasion in the axillary basin.
Information, attention, sentiment, and buzz in the financial markets

This paper aims at focusing on the avenues of research related to the process of information integration by taking explicitly into account investors’ sentiment, investors’ attention, and the buzz hypothesis. New social media introduce change in the way information is processes in the market. Qualitative concepts such as rumor, opinion, sentiment, are often put in the frontstage. Moreover the formal dimensions of information become more important compared to the content of information. This leads to new avenues of research aside the standard information value hypothesis.
Orientation dependence of nonlinearity and TCf in high-Q shear-modes of silicon MEMS resonators

This paper reports the first results that correlate nonlinear Duffing behavior and the temperature coefficient of frequency (TCf) in single-crystal-silicon (SCS) micromechanical resonators vibrating in lateral shear-dominant bulk modes, i.e. face shear (FS) and Lamé modes. Based on the anisotropic material property of SCS, we have derived a model to capture the nonlinear responses and the TCf for these devices in different orientations. The model predicts a clear orientation dependence of nonlinearity and temperature stability in SCS microresonators. These results suggest the possibility of reducing both nonlinearity and TCf by engineering the material properties (e.g. doping).
Epidemiological characteristics of the carriers with coexistence of HBsAg and anti‐HBs based on a community cohort study

The coexistence of HBsAg and anti‐HBs is an atypical serological pattern in HBV infection. There is no epidemiological characteristics of this serological pattern in the community and there is controversy over the molecular mechanisms underlying this pattern. We investigated the epidemiological characteristics of the carriers with HBsAg and anti‐HBs in a longitudinal community cohort study. The prevalence of this atypical serological pattern was 2.93% (122/4169) in HBsAg‐positive populations. The prevalence progressively increased with age from 40 to 70 years old. The rate of HBeAg positive and detectable HBV DNA were both significantly higher in carriers with this pattern than in carriers who were HBsAg positive but anti‐HBs negative (26/122 verse 598/4047, P = 0.046; 86/122 verse 275/529,P < 0.001). After 1 year of follow‐up, 85.19% of the carriers still had coexistence HBsAg and anti‐HBs, 14.81% of the carriers lost their anti‐HBs. Viral sequencing showed that carriers with coexistence of HBsAg and anti‐HBs had higher numbers of residue changes within the S gene than carriers who were HBsAg positive but anti‐HBs negative (2.42 verse 1.33 changes per 100 residues, P < 0.05). Hence, the coexistence of HBsAg and anti‐HBs is a unique serological pattern which may be associated with an increased risk of adverse clinical outcome and may be related to HBsAg immune variants which have genotypic heterogeneity.
Helicobacter pylori Exploits Cholesterol-Rich Microdomains for Induction of NF-κB-Dependent Responses and Peptidoglycan Delivery in Epithelial Cells

ABSTRACT Infection with Helicobacter pylori cag pathogenicity island (cagPAI)-positive strains is associated with more destructive tissue damage and an increased risk of severe disease. The cagPAI encodes a type IV secretion system (TFSS) that delivers the bacterial effector molecules CagA and peptidoglycan into the host cell cytoplasm, thereby inducing responses in host cells. It was previously shown that interactions between CagL, present on the TFSS pilus, and host α5β1 integrin molecules were critical for CagA translocation and the induction of cytoskeletal rearrangements in epithelial cells. As the α5β1 integrin is found in cholesterol-rich microdomains (known as lipid rafts), we hypothesized that these domains may also be involved in the induction of proinflammatory responses mediated by NOD1 recognition of H. pylori peptidoglycan. Indeed, not only did methyl-β-cyclodextrin depletion of cholesterol from cultured epithelial cells have a significant effect on the levels of NF-κB and interleukin-8 (IL-8) responses induced by H. pylori bacteria with an intact TFSS (P < 0.05), but it also interfered with TFSS-mediated peptidoglycan delivery to cells. Both of these effects could be restored by cholesterol replenishment of the cells. Furthermore, we demonstrated for the first time the involvement of α5β1 integrin in the induction of proinflammatory responses by H. pylori. Taking the results together, we propose that α5β1 integrin, which is associated with cholesterol-rich microdomains at the host cell surface, is required for NOD1 recognition of peptidoglycan and subsequent induction of NF-κB-dependent responses to H. pylori. These data implicate cholesterol-rich microdomains as a novel platform for TFSS-dependent delivery of bacterial products to cytosolic pathogen recognition molecules.
Redefining the Age of Clovis: Implications for the Peopling of the Americas

The Clovis complex is considered to be the oldest unequivocal evidence of humans in the Americas, dating between 11,500 and 10,900 radiocarbon years before the present (14C yr B.P.). Adjusted 14C dates and a reevaluation of the existing Clovis date record revise the Clovis time range to 11,050 to 10,800 14C yr B.P. In as few as 200 calendar years, Clovis technology originated and spread throughout North America. The revised age range for Clovis overlaps non-Clovis sites in North and South America. This and other evidence imply that humans already lived in the Americas before Clovis.