Miracle-dz/UniFAR-FTUs huggingface dataset:
A Clinical Comparison of Home-Based and Hospital-Based Exercise Programs Following Arthroscopic Capsulolabral Repair for Anterior Shoulder Instability.

CONTEXT Ideal rehabilitation method following arthroscopic capsulolabral repair surgery for anterior shoulder instability has not been proven yet. Although rapid or slow protocols were compared previously, home- or hospital-based protocols were not questioned before. OBJECTIVE The aim of this prospective unrandomized controlled clinical trial is to compare the clinical outcomes of home-based and hospital-based rehabilitation programs following arthroscopic Bankart repair. DESIGN Nonrandomized controlled trial. SETTING Orthopedics and physical therapy units of a single institution. PATIENTS Fifty-four patients (49 males and 5 females) with an average age of 30.5 (9.1) years, who underwent arthroscopic capsulolabral repair and met the inclusion criteria, with at least 1-year follow-up were allocated into 2 groups: home-based (n = 33) and hospital-based (n = 21) groups. INTERVENTIONS Both groups received identical rehabilitation programs. Patients in the home-based group were called for follow-up every 3 weeks. Patients in the hospital-based group admitted for therapy every other day for a total of 6 to 8 weeks. Both groups were followed identically after the eighth week and the rehabilitation program continued for 6 months. MAIN OUTCOME MEASURES Clinical outcomes were assessed using Disabilities of Arm Shoulder Hand, Constant, and Rowe scores. Mann-Whitney U test was used to compare the results in both groups. Wilcoxon test was used for determining the progress in each group. RESULTS Groups were age and gender matched (P = .61, P = .69). Average number of treatment sessions was 13.8 (7.3) for patients in the hospital-based group. Preoperative Disabilities of Arm Shoulder Hand (27.46 [11.81] vs 32.53 [16.42], P = .22), Constant (58.23 [14.23] vs 54.17 [10.46], P = .13), and Rowe (51.72 [15.36] vs 43.81 [19.16], P = .12) scores were similar between groups. Postoperative scores at sixth month were significantly improved in each group (P = .001, P = .001, and P = .001). No significant difference was observed between 2 groups regarding clinical scores in any time point. CONCLUSIONS We have, therefore, concluded that a controlled home-based exercise program is as effective as hospital-based rehabilitation following arthroscopic capsulolabral repair for anterior shoulder instability.
Mental health, functional ability, and health-related quality of life in elderly patients attending a tertiary hospital of Patna

Background: With changing socioeconomic, demographic, and development scenario, there is a cultural shift in looking after the elderly population which may lead to depression in this age group. Materials and Methods: The study was a hospital-based cross-sectional study conducted in the orthopedic department of a tertiary care setting on 157 elderly individuals. This study was conducted with objectives to estimate the proportion of depression using the Geriatric Depression Scale Short Form (GDS-SF) questionnaire along with its associated factors in geriatric population coming to the orthopedic department of the institute. The study tools were GDS-SF, Katz Index of Independence in activities of daily living (ADL), the Lawton instrumental ADL, and health-related quality of life by the Centers for Disease Control. Results: The proportion of depressed individuals was 70/157 (44.6%) using GDS as a tool. The maximum number was in the age group of 60–74 years. Women outnumbered men (51.3% vs. 38.31%) for depression. The depression using GDS score was more prevalent in rural elderly, illiterate, and elderly who were economically dependent on their children and who belonged to lower middle socioeconomic status. Approximately 98% of the study participants were found to be independent using ADL. Approximately 60% males and 68% females were dependent for the instrumental ADL using Lawton score. Most of the study participants had arthritis as a major impairment sharing almost equal proportion among males and females. Conclusion: The current study concludes that there is a very high proportion of elderly subjects who are experiencing depression using the GDS-SF tool. There should be regular screening for this disease in this age group even in a tertiary care setting.
Multidetector computed tomography and magnetic resonance imaging findings in pulmonary hydatid cysts

Aim: Computed tomography (CT) and magnetic resonance imaging (MRI) are diagnostic modalities in pulmonary hydatid disease. We aimed to present CT and MRI findings in pulmonary hydatid disease. Material and Methods: CT and MRI findings of pulmonary hydatid cysts from January 2011 through June 2018 were evaluated retrospectively. CT images of 112 patients and MRI images of 27 patients were evaluated. Patients’ gender and ages, lesion number and distribution, concomitant organ involvement, complications, HU density of lesions on CT and signal characteristics of lesions on MRI were analyzed. T2 hypointense rim, T1 and T2 signal intensity, daughter vesicle and detached membranes were the evaluated parameters on MRI. Results: 147 hydatid cyst lesions of 119 (66 female, 53 male) patients with a mean age of 39.4±19.6 years were included in the study 62 (52.1%) of patients had isolated lung involvement. 79 of 119 patients (66.4%) had solitary lung lesion. Mean CT density of cysts were 16 HU. 25 of 32 cysts showed T2 hypointense rim on MRI. Conclusion: Imaging plays important role in diagnosis and presurgical evaluation of pulmonary hydatid disease. CT is mostly used in diagnosis; MRI should be a choice particularly in pediatric population.
Radiológiai osztályon dolgozó szakdolgozók kiégési szintje Magyarországon

Bevezetés: A segítő szakmákban dolgozó szakembereket veszélyeztető kiégésnek széles körű negatív hatásai lehetnek, ami a betegellátás minőségét és az egészségügyi rendszer hatékonyságát is befolyásolhatja. Célkitűzés: A kutatás célja volt feltárni, hogy a magyarországi radiológiai osztályon dolgozó szakdolgozókat milyen mértékben veszélyezteti a kiégés. Módszer: Kvantitatív, keresztmetszeti, leíró kutatás keretében az adatgyűjtésre 2018. június–szeptember intervallum­ ban online felületen megosztott kérdőív segítségével, radiológiai osztályon dolgozó szakdolgozók körében került sor egyszerű, nem véletlenszerű mintavétel alkalmazásával, anonim módon. A saját szerkesztésű kérdőív a szociodemog­ ráfiai és a munkavégzés jellegével kapcsolatos jellemzők mellett a Maslach Burnout Inventory (MBI) nemzetközileg validált kérdőívet is tartalmazta. Eredmények: Az adatok tisztítását követően összesen 404 fő válaszait vontuk be a statisztikai elemzésbe. A többsé­ gében megyei kórházakban alkalmazott szakdolgozók átlagosan 18,3 éve (SD 13,7) dolgoznak az egészségügyi ellá­ tórendszerben. A kiégésnek a deperszonalizáció és emocionális kimerülés dimenziójában a minta enyhén emelkedett értékű kiégést mutat. Az iskolai végzettség, az életkor és az egészségügyben eltöltött évek száma szignifikánsan befo­ lyásolta mindhárom, kiégéssel kapcsolatos dimenziót (p≤0,05). A 31–35 éves korcsoport és a 16–20 éve a pályán lévő válaszadók tekinthetők a legveszélyeztetettebb csoportnak a kiégés mindhárom dimenziójában. Az MSc­végzettség­ gel rendelkezők emocionális kimerülési értéke szignifikánsan alacsonyabbnak bizonyult társaikéhoz viszonyítva. Következtetés: A deperszonalizáció és az emocionális kimerülés emelkedett értéke jelző értékkel bírhat a munkáltatók számára. A kapott eredmények a nemzetközi szakirodalomban leírtakkal jól korrelálnak. Orv Hetil. 2019; 160(27): 1070–1077.
A Clinicopathological Study of Solitary Thyroid Nodule

Introduction:Common presentation of thyroid disorders is solitary nodule. A discrete swelling in an otherwise impalpable gland is termed as solitary nodule of thyroid. The majority of solitary thyroid nodules are benign. The incidence of malignancy is 10-20%, being more common in females with a mean age of 35 years.The object of the study was to identify the incidence of malignancy in solitary nodule thyroid which emphasizes on the early diagnosis and adequate treatment. Materials and Methods: The study was carried out in the department of ENT and Head-Neck Surgery of Rangpur Medical College Hospital, Rangpur and Shaheed Ziaur Rahman Medical College Hospital, Boruga in 50 patients with solitary thyroid nodule from July 2013 to June 2015. Results: The solitary thyroid nodules were seen in 1.76% of surgical admissions. The mean age of the incidence of solitary thyroid nodule is 35 years. The incidence of malignancy in solitary thyroid nodule is 18.51%. The solitary thyroid nodules were frequent in females than males in the ratio of 6.71:1. Conclusion: It is concluded from the present study that a remarkable proportion 10% of solitary thyroid nodules was malignant with females preponderance which emphasizes on the early diagnosis and adequate treatment. Medicine Today 2019 Vol.31(2): 85-88
The Impact of the Term of Preliminary Traction and the Age on the Development of Aseptic Necrosis of Caput Femori after Conservative Therapy of Hip Dislocation

Background. The problem of the therapy of congenital hip dislocation (CHD) in children was always linked with sequlae appearing during and after the therapy. The objective. In this regard the objective of our study was to answer the question if duration of the functional traction effects the frequency of caput femori (CF) aseptic necrosis development and whether the age of CHD initial therapy had an impact on the further prognosis of hip joint (HJ) development as a whole. Materials and methods. We examined 276 patients (319 HJ), who had plaster traction before reduction of CHD. Patients were divided to groups according to age at the time of CHD primary therapy. Results. Out of 319 HJ fifty nine cases had development of CFAN (18%). The lowest parameter was detected in the group of patients from 3 to 6 months in 8%, while the highest one was determined in the age 24036 months, where it was equal to 53%. In cases of preliminary traction more than 3 weeks development of CFAN was equal to 6%. Conclusion. Duration of preliminary traction in conservative therapy of CHD is very important. Prognosis of complete development of HJ was significantly worse in children above 1 compared to those from 3 to 12 months.
Issues and Types of Adverse Selection and Negative Selection

In a relatively high number of cases, there are selection criteria in everyday life, the implementation of which clearly does not support the development of the economy, even in the short term. At the same time, the phenomenon of adverse selection raises its head relatively rarely in reality, since it is equally dependent on the preconditions of a high degree of hidden information and the complete good faith of the stakeholders. In comparison, negative selection is – by necessity – a more frequent case. In such cases, the relevant information is available to the parties. At the same time, the individual or group possessing the information consciously abuses their dominant position. Moreover, this specifically disadvantages those who currently best comply with the existing selection requirements, but in spite of this are vulnerable due to the lack of a proper negotiating position or interestasserting capability. However, the dominant position or power possessed by the relevant party can also be used “according to its intended purpose”, which enables the implementation of positive selection that is very likely to promote development.
Chronic Kidney Disease, Pre and Post Hemodialysis

Chronic renal failure is the progressive loss of function of kidney and patient requires a long treatment in the form of renal replacement therapy. Hemodialysis is one of the widely used renal replacement therapy, during which body’s waste products, including creatinine, urea and excess water, are removed. The current study was designed to investigate the impact of hemodialysis on the removal of Non Proteinous Nitrogenous waste from the body. Sixty Chronic Kidney Disease patients were were enrolled and their serum was analysed for various renal parameters. Results showed that there was significant decrease (p<0.001) in serum urea, creatinine levels post Hemodialysis as compared to pre Hemodialysis, while there was significant increase (p<0.001) in serum calcium levels.
Argo: An Exascale Operating System and Runtime

Exascale supercomputers are expected to comprise hundreds of thousands of heterogeneous compute nodes linked by complex networks. Those compute nodes will have an intricate mix of general-purpose multi-cores and special-purpose accelerators targeting compute-intensive workloads with deep multi-level memory hierarchies. As such, the HPC community expects exascale systems to require new programming models, to take advantage of both intra-node and inter-node parallelism. The Argo project, funded under the DOE ExaOSR initiative, aims to provide an Operating System and Runtime (OS/R) designed to support extreme-scale scientific computations. With this goal in mind, Argo seeks to efficiently exploit new processor, memory and interconnect technologies while addressing the new modalities, programming environments, and workflows expected at exascale. At the heart of this project are four key innovations: dynamic reconfiguring of node resources in response to workload changes, allowance for massive concurrency, a hierarchical framework for management of nodes, and a cross-layer communication infrastructure that allows resource managers and optimizers to communicate efficiently across the platform. These innovations will result in an open-source prototype system that is expected to form the basis of production exascale systems deployed in the 2020 timeframe. We provide here a overall description of the project, before highlighting recent achievements in performance and integration with existing systems.
A zenei teljesítményszorongás: prevalencia, kialakulás, társuló zavarok és személyiségvonások, kezelési lehetőségek

A tarsas kapcsolatok hianya es a szocialis funkciok romlasa, az alacsony enhatekonysag es ennek kovetkezteben a csokkent eletminőseg a szorongasos zavarok gyakori velejaroi. A tarsas kornyezetben t.
Plaque Regression and Endothelial Progenitor Cell Mobilization With Intensive Lipid Elimination Regimen (PREMIER)

Supplemental Digital Content is available in the text. Background: Low-density lipoproteins (LDLs) are removed by extracorporeal filtration during LDL apheresis. It is mainly used in familial hyperlipidemia. The PREMIER trial (Plaque Regression and Progenitor Cell Mobilization With Intensive Lipid Elimination Regimen) evaluated LDL apheresis in nonfamilial hyperlipidemia acute coronary syndrome patients treated with percutaneous coronary intervention. Methods: We randomized 160 acute coronary syndrome patients at 4 Veterans Affairs centers within 72 hours of percutaneous coronary intervention to intensive lipid-lowering therapy (ILLT) comprising single LDL apheresis and statins versus standard medical therapy (SMT) with no LDL apheresis and statin therapy alone. Trial objectives constituted primary safety and primary efficacy end points and endothelial progenitor cell colony-forming unit mobilization in peripheral blood. Results: Mean LDL reduction at discharge was 53% in ILLT and 17% in SMT groups (P<0.0001) from baseline levels of 116.3±34.3 and 110.7±32 mg/dL (P=0.2979), respectively. The incidence of the primary safety end point of major peri-percutaneous coronary intervention adverse events was similar in both groups (ILLT, 3; SMT, 0). The primary efficacy end point, percentage change in total plaque volume at 90 days by intravascular ultrasound, on average decreased by 4.81% in the ILLT group and increased by 2.31% in the SMT group (difference of means, −7.13 [95% CI, −14.59 to 0.34]; P=0.0611). The raw change in total plaque volume on average decreased more in the ILLT group than in the SMT group (−6.01 versus −0.95 mm3; difference of means, −5.06 [95% CI, −11.61 to 1.48]; P=0.1286). Similar results were obtained after adjusting for participating sites, age, preexisting coronary artery disease, diabetes mellitus, baseline LDL levels, and baseline plaque burden. There was robust endothelial progenitor cell colony-forming unit mobilization from baseline to 90 days in the ILLT group (P=0.0015) but not in SMT (P=0.0844). Conclusions: PREMIER is the first randomized clinical trial to demonstrate safety and a trend for early coronary plaque regression with LDL apheresis in nonfamilial hyperlipidemia acute coronary syndrome patients treated with percutaneous coronary intervention. Registration: URL: https://www.clinicaltrials. gov. Unique identifier: NCT01004406 and NCT02347098.
Perspectives of Afghan refugee mothers on the experience of caring for a child with cancer: a qualitative analysis.

Background Cancer in children causes many challenges for the family. When a refugee family experiences it, its impacts may be different and more specific considerations for care may be needed. Aims This study aimed to explore the experiences of Afghan mothers living in the Islamic Republic of Iran who had a child with cancer. Methods This was a qualitative study, conducted in 2017, of Afghan refugee women with children diagnosed with cancer and referred to a cancer referral hospital in Tehran; they were selected through purposive sampling. Face-to-face, semi-structured and in-depth interviews were conducted for data collection until data saturation was reached. Conventional content analysis was done. MAXQDA 10 was used for organizing the data. Results Nine Afghan mothers were interviewed. They were aged 24-44 years and the children were aged 2-9 years. A primary theme called "passive acceptor" was found with five subthemes: chronic suffering, health issues, lack of skills, maladaptive coping and enthusiasm. The mothers were struggling to cope with the challenges of caring for a child with cancer both financially, physically and emotionally. Conclusion In spite of many issues in common with similar groups in other countries, Afghan mothers appear to need to greater assistance when it comes to seeking help and understanding for the care for their child with cancer, possibly because of cultural barriers to self-empowerment. Tailored care plans are recommended for Afghan refugee mothers in the Islamic Republic of Iran.
LINK-A lncRNA participates in the pathogenesis of glioma by interacting with survivin

Long intergenic non-coding RNA for kinase activation (LINK-A) long non-coding RNA (lncRNA) has been characterized in triple negative breast cancer, but its potential involvement in glioma has not been investigated. In the present study, serum levels of LINK-A lncRNA and survivin in patients with glioma and healthy controls were determined by RT-qPCR and ELISA, respectively. The diagnostic value of serum LINK-A lncRNA for glioma was evaluated by receiver operating characteristic (ROC) curve analysis. Potential correlations between serum levels of LINK-A lncRNA and survivin were analyzed by Pearson correlation coefficient. LINK-A lncRNA siRNA, LINK-A lncRNA-carrying expression vector and survivin-carrying expression vector were transfected into glioma cells, and the effects on LINK-A lncRNA expression, survivin expression and cell apoptosis were explored by RT-qPCR, western blot analysis and annexin V/propidium iodide staining. It was observed that the serum levels of LINK-A lncRNA and survivin were significantly higher in patients with glioma compared with healthy controls. Increased levels of LINK-A lncRNA distinguished glioma patients from healthy controls, based on ROC curve analysis. Serum levels of LINK-A lncRNA and survivin were positively correlated in glioma patients, but not in healthy controls. Overexpression of LINK-A lncRNA led to increased survivin protein expression, while survivin overexpression had no effect on LINK-A lncRNA expression. LINK-A lncRNA and survivin overexpression each reduced glioma cell apoptosis, but LINK-A lncRNA siRNA-mediated knockdown increased apoptosis. Survivin overexpression attenuated the inducing effects of LINK-A lncRNA knockdown on apoptosis. In conclusion, LINK-A lncRNA inhibited glioma cell apoptosis potentially by the upregulation of survivin. The present study revealed that LINK-A may serve as possible diagnostic marker for glioma.
Drug Utilization Study in Epilepsy in A Tertiary Care Hospital

Treatment of epilepsy is quite challenging as it requires the antiepileptic drugs to be taken for a long duration, sometimes throughout the lifetime of the patient. But such chronic drug intake results in adverse effects, drug interactions and added economic and emotional distress to the patients. It is therefore of utmost importance to analyze the pattern of prescription of antiepileptic drugs, the concurrent medications in epilepsy. The present study was conducted to collect, assess and understand the above data and also to analyze the rationality and correctness of prescription using the WHO prescription indicators. A total of 100 case records of patients diagnosed with epilepsy was analyzed and the data was recorded. We have total 34 children and 66 adult patients in our study. Generalized tonic-clonic seizures was the common type of seizure. Phenytoin was the most commonly prescribed antiepileptic drug. 1/3rd of the patients needed more than one drug for adequate seizure control and the most common add on drug was levetiracetam. Also, the average number of drugs prescribed to the patients was 6 which included drugs given for concomitant illnesses as well. A total of 561 medicines were prescribed which included the drugs prescribed for concomitant illnesses as well. Average number of medicines per prescription was 6. Prescription by generic name was seen in 42% of the cases. An injection was prescribed in 66% of the prescriptions. An antibiotic was encountered in 38% of the prescriptions. Most of the epileptic patients are subjected to polypharmacy which puts them at a higher risk of side effects, drug interactions and financial burden. Physicians should minimize the use of drugs and look into the rationality of each prescription.
Epidemiological Profile and Incidence of Hip Fractures in Greece

Introduction: This study was designed to determine the epidemiological profile of hip fractures among Greek population with special importance to the cause of fracture, their characteristics, the treatment instituted and to assess the incidence. Methods: The current study conducted in a single hospital in the northern part of Greece, in the regional unit of Grevena, during the 2016 calendar year. Patients themselves, or a relative member or a caregiver, were interviewed by a questionnaire regarding to the past medical history, time and place of the fracture occurrences. Results: The 73 patients included in the study presented a mean age of 83.5 years, with a male-to-female ratio of 1:2.17. Falling from the same level was the cause of 97.6% of the fractures. Transtrochanteric fractures accounted for 52.1% of the fractures, femoral neck fractures, 38.4% and subtrochanteric fractures, 9.6%. More fractures are seen during the summer months (32.9%), inside the house (61.6%) and during the morning (49.3%). The overall annual incidence rate was 672.2 per 100,000 inhabitants (442.6 and 882.9 per 100,000 male and female, respectively). Length of waiting time to surgery was 1.87 days and length of hospital stay was 8.46 days, without statistical significance according to the type of surgery, the age group and the associated comorbidities. Hypertension (87.7%) was the most common comorbidity, followed by heart disease (50.7%) and depression (31.5%). Conclusion: The patients attended at this hospital presented an epidemiological profile similar to the worldwide literature. Hip fracture rates in the region of Grevena are higher than other regions in Greece, such as Athens and Crete.