Miracle-dz/UniFAR-FTUs huggingface dataset:
DEVELOPMENT OF FISH FINGER FROM ROHU ( Labeo rohita ) AND ITS QUALITY EVALUATION DURING REFRIGERATED STORAGE CONDITION

Study was conducted to study the shelf life, proximate composition, biochemical, microbiological and organoleptic changes in fish finger prepared from minced meat of fish rohu (Labeo rohita) with suitable recipe. Prepared fish finger was stored in refrigerated condition at 4 0 C ± 1 0 C for 11 days. The yield rate of minced meat from the whole fish was 39.31 %. The moisture and protein content of fish finger during refrigerated storage was decreased significantly from 64.90 % to 57.36 % and 18.5 % to 16.29 % (P < 0.01) respectively while fat and ash content were increased significantly from 8.68 % to 15.33 % and 2.5 % to 3.43 % (P<0.01) respectively. The pH of fish finger decreased significantly (P<0.01) from 6.95 to 6.44. PV of fish finger increased from 10.73 to 17.8 meqO2/kg of fat till the end of 5 th day of storage and subsequently decreased to 10.4 meqO2/kg of fat at the end of 15 days of storage period. The pattern of change in free fatty acid content and TBA of fish finger was gradual increment from 0.0014 to 0.0046 % of oleic acid and 0.095 to 1.030 mg MA/kg of sample respectively (P<0.01). The TVBN content steadily increased significantly (P<0.01) from an initial value of 2.65 to 4.43 mg/100g sample during 15 days refrigerated storage. TPC and psychrophilic bacterial count increased steadily (P<0.01) from the initial count of 5.68 x 10 2 cfu/g of sample to 1.72 x 10 5 cfu/g of sample and from 2.54 x 10 2 cfu/g of sample to 1.24 x 10 5 cfu/g of sample respectively. The overall mean acceptability scores declined significantly (P<0.01) with increase storage period. The ideal shelf life for storing the fish finger in refrigerated condition was found as 9 days.
A Qualitative Exploration of the DIGCOMP Digital Competence Framework: Attitudes of students, academics and administrative staff in the health faculty of a UK HEI

This paper reports upon findings of a series of semi-structured interviews with students, academics and administrative staff from a health care faculty in a UK Higher Education Institution (HEI). Exploring their experiences of mapping to the EU DIGCOMP Digital Competence Framework, a hermeneutic lens enables a more nuanced approach to attitudes towards Digital Competence (DC). One of the eight lifelong learning key-competences required for managers, doctors, nurses and other health-related professionals, DC is crucial to professional development. Defined by 14 themes, the findings express the participants’ experiences, knowledge and level of comprehension of the subject. Our findings indicate students are conflating digital social media skills with their skills for the workplace, resulting in over-confidence; academics raising concerns about work/private life balance offered by the affordances of handheld devices; administrative staff that are far more confident and managing a range of technology’s effectively. The research further reveals that the DIGICOMP framework is applicable as a generic framework for professional practice.
New Class of Blue Animal Pigments Based on Frizzled and Kringle Protein Domains*

The nature of coloration in many marine animals remains poorly investigated. Here we studied the blue pigment of a scyfoid jellyfish Rhizostoma pulmo and determined it to be a soluble extracellular 30-kDa chromoprotein with a complex absorption spectrum peaking at 420, 588, and 624 nm. Furthermore, we cloned the corresponding cDNA and confirmed its identity by immunoblotting and mass spectrometry experiments. The chromoprotein, named rpulFKz1, consists of two domains, a Frizzled cysteine-rich domain and a Kringle domain, inserted into one another. Generally, Frizzleds are members of a basic Wnt signal transduction pathway investigated intensely with regard to development and cancerogenesis. Kringles are autonomous structural domains found throughout the blood clotting and fibrinolytic proteins. Neither Frizzled and Kringle domains association with any type of coloration nor Kringle intrusion into Frizzled sequence was ever observed. Thus, rpulFKz1 represents a new class of animal pigments, whose chromogenic group remains undetermined. The striking homology between a chromoprotein and members of the signal transduction pathway provides a novel node in the evolution track of growth factor-mediated morphogenesis compounds.
Association of variants in MANEA with cocaine-related behaviors.

CONTEXT Cocaine dependence (CD) and related behaviors are highly heritable, but no genetic association has been consistently demonstrated. A recent genome-wide study of drug dependence identified an association between cocaine-induced paranoia (CIP) and a single-nucleotide polymorphism (SNP) in the alpha-endomannosidase (MANEA) locus in a family-based sample of European Americans and African Americans. OBJECTIVE To conduct a comprehensive genetic association study of the MANEA locus with CD and CIP. DESIGN Genome-wide association study. SETTING Four university hospitals. PARTICIPANTS A total of 3992 individuals from 2 family-based and 2 case-control samples. INTERVENTION Participants were classified as having CD or CIP or as a control using the Semi-Structured Assessment for Drug Dependence and Alcoholism. They were genotyped for 11 SNPs spanning MANEA and its surrounding region. MAIN OUTCOME MEASURE Association of CD and CIP with individual SNPs and haplotypes. RESULTS Cocaine-induced paranoia was associated with 6 SNPs in the European American families and 9 SNPs in the African American families. The strongest evidence in the total sample of families was observed in 3 markers located in the promoter and 3' untranslated regions (P < .001). The association of MANEA SNPs with CD in both family samples was much weaker. In the African American case-control sample, multiple markers were significantly associated with CIP and CD; CIP and CD were also significantly associated with a 2-SNP haplotype in the European American case-control sample. The A allele of the 3' untranslated region SNP rs9387522 was associated with increased risk of CIP in all 4 data sets. CONCLUSIONS Our findings suggest that CD and associated behaviors may involve biological pathways not typically thought to be associated with brain metabolism.
Does Patient Rurality Predict Quality Colon Cancer Care?: A Population-Based Study

BACKGROUND: More than 50 million people reside in rural America. However, the impact of patient rurality on colon cancer care has been incompletely characterized, despite its known impact on screening. OBJECTIVE: Our study sought to examine the impact of patient rurality on quality and comprehensive colon cancer care. DESIGN: We constructed a retrospective cohort of 123,129 patients with stage 0 to IV colon cancer. Rural residence was established based on the patient medical service study area designated by the registry. SETTINGS: The study was conducted using the 1996–2008 California Cancer Registry. PATIENTS: All of the patients diagnosed between 1996 and 2008 with tumors located in the colon were eligible for inclusion in this study. MAIN OUTCOME MEASURES: Baseline characteristics were compared by rurality status. Multivariate regression models then were used to examine the impact of rurality on stage in the entire cohort, adequate lymphadenectomy in stage I to III disease, and receipt of chemotherapy for stage III disease. Proportional-hazards regression was used to examine the impact of rurality on cancer-specific survival. RESULTS: Of all of the patients diagnosed with colon cancer, 18,735 (15%) resided in rural areas. Our multivariate models demonstrate that rurality was associated with later stage of diagnosis, inadequate lymphadenectomy in stage I to III disease, and lower likelihood of receiving chemotherapy for stage III disease. In addition, rurality was associated with worse cancer-specific survival. LIMITATIONS: We could not account for socioeconomic status directly, although we used insurance status as a surrogate. Furthermore, we did not have access to treatment location or distance traveled. We also could not account for provider or hospital case volume, patient comorbidities, or complications. CONCLUSIONS: A significant portion of patients treated for colon cancer live in rural areas. Yet, rural residence is associated with modest differences in stage, adherence to quality measures, and survival. Future endeavors should help improve care to this vulnerable population (see video, Supplemental Digital Content 1, http://links.lww.com/DCR/A143).
Impact of Facebook on leisure travel behavior of Singapore residents

Purpose Social media has fundamentally changed the leisure travel behavior of Singapore residents. The purpose of this paper is to focus on Facebook and its impact on travel behavior. The study focuses on Singapore residents. Design/methodology/approach A total of 16 input and five output variables were tested, with a sample of 203 Facebook users residing in Singapore. Primary data modeling was done using ADANCO, a structural equation modeling tool that uses composite modeling approach for hypothesis testing. The analysis performed an estimated structural model and then determined the best model fit by measuring reliability, validity and path analysis and estimating model parameters. Findings Research findings indicate that Facebook has had a strong behavioral influence on the frequency of travel, itinerary planning and social sharing, while it had no impact during the destination-selection stage of travel planning. Originality/value Facebook’s influence on leisure travel behavior confirms the theory of planned behavior proposed by Icek Ajzen. From Facebook’s perspective, the outcome of this study is helpful in recommending the best use of the platform for destination providers.
Target capital ratio and optimal channel(s) of adjustment: a simple model with empirical applications to European banks

ABSTRACT Why do banks decide to reach their target capital ratio by selling assets and/or issuing new shares? To answer this question, we offer a simple framework in which each channel of adjustment is costly; underwriting and dilution costs for equity issuance, profit reduction and price impact for asset sale. We make the assumption that the aim of the bank is to minimize the total adjustment cost subject to the target’s constraint and we derive its optimal strategy. The solution is formulated in terms of two critical thresholds for which we give an explicit formula. We then compare our model’s predictions to the decisions taken by two European systemic banks (Deutsche Bank and UniCredit) to issue new shares in 2017 and for which the target ratio was publicly disclosed. We show that the predictions of the model are consistent with the observed decisions.
Two Essays on Sell Side Equity Analysts

We contribute to the debate surrounding sell-side analyst skill in a novel way. In particular, we investigate whether analysts’ incorporate salient firm-level information in their recommendations or target prices that has been shown by the academic literature to predict future abnormal performance (i.e., anomalies). In aggregate, there is little relation between analysts’ recommendation levels and anomaly prescriptions, however, analysts’ target price estimates are significantly higher for stocks in the “short” leg of an anomaly when compared to stocks in the “long” leg. In the cross section, we do not find evidence that certain brokerage firms or “All-star” analysts are anomaly savvy. However, evidence suggests that analyst’s experience tends to mitigate such bias. We conjecture that the value of analysts’ research would be significantly enhanced if analysts paid attention to academic research.
The euro crisis: some reflexions on institutional reform

The debate on the euro crisis understandably has had a strong short-term focus. Avoiding short-term disaster has been tantamount and the long-term sustainability issue sometimes neglected; yet, the institutional failure of the euro area forces us to reconsider current arrangements in order to restore credibility and sustainability. The article discusses various paths for the reform of the overall governance, from fi scal management to banking regulation, through the recent proposals to mutualise and repackage part of the sovereign debts into a supranational one or to introduce joint-and-several liability.
Bacterial adhesion to food contacting surfaces

Contamination of kitchen surfaces, during food preparation, due to bacteria present in foodstuff is one of the main causes of foodborne outbreaks. Cells adhered to those surfaces of domestic kitchens are not easily removed by normal cleaning procedures. Therefore, they can be a source of contamination for other foods and objects. Several studies indicate that various pathogenic bacteria like Listeria monocytogenes, Salmonella spp. , Campylobacter, E. coli and Staphylococcus aureus survive in kitchen utensils, hands and in bench cover materials. In this way it is of utmost importance to know the factors responsible for the adhesion of pathogenic bacteria to kitchen materials in order to select the material less prone to bacterial colonization. Accordingly, this chapter will focus on the study of the adhesion of strains of Listeria monocytogenes and Salmonella Enteritidis to materials commonly used in kitchens (stainless steel 304, marble, granite, glass, polypropylene from a bowl and a cutting board and two kinds of silestone).
Helicobacter pylori strains vary cell shape and flagellum number to maintain robust motility in viscous environments

The helical shape of the human stomach pathogen Helicobacter pylori has been suggested to provide mechanical advantage for penetrating the viscous stomach mucus layer. Using single‐cell tracking and quantitative morphology analysis, we document marked variation in cell body helical parameters and flagellum number among H. pylori strains leading to distinct and broad speed distributions in broth and viscous gastric mucin media. These distributions reflect both temporal variation in swimming speed and morphologic variation within the population. Isogenic mutants with straight‐rod morphology showed 7–21% reduction in speed and a lower fraction of motile bacteria. Mutational perturbation of flagellum number revealed a 19% increase in speed with 4 versus 3 median flagellum number. Resistive force theory modeling incorporating variation of both cell shape and flagellum number predicts qualitative speed differences of 10–30% among strains. However, quantitative comparisons suggest resistive force theory underestimates the influence of cell body shape on speed for helical shaped bacteria.
Pollution characteristics and environmental risk assessment of typical veterinary antibiotics in livestock farms in Southeastern China

Scientific interest in pollution from antibiotics in animal husbandry has increased during recent years. However, there have been few studies on the vertical exposure characteristics of typical veterinary antibiotics in different exposure matrices from different livestock farms. This study explores the distribution and migration of antibiotics from feed to manure, from manure to soil, and from soil to vegetables, by investigating the exposure level of typical antibiotics in feed, manure, soil, vegetables, water, fish, and pork in livestock farms. A screening environmental risk assessment was conducted to identify the hazardous potential of veterinary antibiotics from livestock farms in southeast China. The results show that adding antibiotics to drinking water as well as the excessive use of antibiotic feed additives may become the major source of antibiotics pollution in livestock farms. Physical and chemical properties significantly affect the distribution and migration of various antibiotics from manure to soil and from soil to plant. Simple migration models can predict the accumulation of antibiotics in soil and plants. The environmental risk assessment results show that more attention should be paid to the terrestrial eco-risk of sulfadiazine, sulfamethazine, sulfamethoxazole, tetracycline, oxytetracycline, chlorotetracycline, ciprofloxacin, and enrofloxacin, and to the aquatic eco-risk of chlorotetracycline, ciprofloxacin, and enrofloxacin. This is the first systematic analysis of the vertical pollution characteristics of typical veterinary antibiotics in livestock farms in southeast China. It also identifies the ecological and human health risk of veterinary antibiotics.
1998 ANNUAL REPORT OF THE CALIFORNIA DUI MANAGEMENT INFORMATION SYSTEM

In this seventh annual legislatively mandated report, 1995 and 1996 DUI (Driving Under the Influence) data from diverse sources were compiled and cross-referenced for the purpose of developing a single comprehensive DUI data reference and monitoring system. This report presents crosstabulated information on DUI arrests, convictions, court sanctions, administrative actions and alcohol-involved accidents. In addition, this report provides an evaluation of the effectiveness of alternative court and administrative sanctions (including alcohol treatment programs and license actions) upon the postconviction records of first and second DUI offenders. The postconviction driving records of DUI offenders arrested in 1989, 1993, and 1995 were evaluated for seven-, three-, and one-year periods, respectively.
Building Capacity for System-Level Change in Schools: Lessons from the Gatehouse Project

The Gatehouse Project is an innovative, comprehensive approach to mental health promotion in secondary schools. It sets out to promote student engagement and school connectedness as the way to improve emotional well-being and learning outcomes. The key elements of the whole-school intervention are the establishment and support of a school-based adolescent health team; the identification of risk and protective factors in each school’s social and leaning environment from student surveys; and, through the use of these data, the identification and implementation of effective strategies to address these issues. The project evaluation used a cluster-randomized controlled trial design involving 26 schools with initial results demonstrating considerable success in reducing smoking rates among Year 8 children. This article describes and accounts for how system-level changes have been made in schools through a process of capacity building. This encourages teachers, parents, and students to view the core business of education differently.
The inflammatory cycle: a method of study in Hurler's disease.

In 1947, Rebuck1devised a simple technique for the study of inflammation. After abrasion of the skin, a sterile glass cover slip is applied and allowed to remain in contact with the skin for a variable period of time. The cover slips are removed at intervals throughout a 24-hour period, fixed to a glass slide with clarite or balsam, and stained with Wright-Giemsa. With this technique, one is able to follow the orderly progression of events at the inflammatory site. In normal persons, a highly reproducible sequence of events is observed. Initially, typical polymorphonuclear leukocytes predominate. In the four-six-hour sampling lymphocytes or small mononuclear cells appear in the exudate, and in subsequent samples they are present in increasing numbers. The mononuclear cells appear to develop into hematogenous macrophages between the 8- and 14-hour stages. In the 18- to 24-hour stages, the mononuclear macrophages display increases in cytoplasmic nuclear ratio,
Genital tract group B streptococcal colonization in pregnant women: a South Indian perspective.

INTRODUCTION During the last few decades, group B Streptococcus (GBS) has emerged as an important pathogen. The major reservoirs for GBS are the vagina and the peri-anal regions/rectum, and the colonization of these regions is a risk factor for subsequent infection in pregnant women and newborns. METHODOLOGY A prospective study was performed to determine the prevalence of GBS colonization in the vagina and rectum of pregnant women and the antibiotic susceptibility pattern of the isolates. We also aimed to identify risk factors associated with GBS colonization. The vaginal and rectal swabs were inoculated in Todd-Hewitt broth and later subcultured on blood agar for isolation of GBS. RESULTS A total of 300 pregnant women were enrolled in the study. GBS strains were isolated from seven out of 300 patients, corresponding to a colonization rate of 2.3%. Of the seven patients carrying GBS, isolates were cultured only from vaginal swabs in two cases (28.6%), only from rectal swabs in two cases (28.6%) from both vaginal and rectal swabs in three cases (42.9%). Heavy colonization was present only in 42.9% (3/7) of antenatal women. None of the seven isolates were resistant to penicillin or clindamycin, while one isolate (14.3%) was resistant to erythromycin and five isolates (71.4%) were resistant to tetracycline. Multigravid women and those with previous spontaneous abortion were more frequently colonized by GBS. CONCLUSION The GBS colonization rate in our study was low. No resistance to penicillin or clindamycin was seen, while the majority of the isolates were resistant to tetracycline.
Do Tests of Capital Structure Theory Mean What They Say?

In the presence of frictions, firms adjust their capital structure infrequently. As a consequence, in a dynamic economy the leverage of most firms is likely to differ from the “optimum” leverage at the time of readjustment. This paper explores the empirical implications of this observation. I use a calibrated dynamic trade‐off model to simulate firms' capital structure paths. The results of standard cross‐sectional tests on these data are consistent with those reported in the empirical literature. In particular, the standard interpretation of some test results leads to the rejection of the underlying model. Taken together, the results suggest a rethinking of the way capital structure tests are conducted. (This abstract was borrowed from another version of this item.)
The Effect of Business Development Services on Small Medium Enterprises (SMEs) Performance

This research aims to investigate the effect of Business Development Services (BDS), namely the non-financial services and financial services on the performance of manufacturing Small Medium Enterprises (SMEs) in Sabah, Malaysia. Business development services are recognised as the support services to SMEs, aimed to assist SMEs in overcoming internal and external constraints in its development, thus, improving its performance. A self-administered questionnaire was used to collect data from 161 SMEs within the manufacturing sector in Sabah. Partial Least Square (PLS) was employed to analyse data collected. The results reveal that only financial support has an effect on SMEs performance, whilst contrary to expectation, non-financial support was found to have no effect on SMEs performance in Sabah, Malaysia. The outcome of this study provided significant information, especially to the government agencies responsible for the development of SMEs such as SME Corporation Malaysia. They should evaluate further the existing programmes and guidelines and enforce more effective policies to improve the performance of SMEs in Malaysia, particularly in Sabah.