Miracle-dz/UniFAR-FTUs huggingface dataset:
Efficient replication of the arginine-glycine-aspartic acid (RGD) lacking Human Parechoviruses in 3D Human Airway Epithelial Cell models

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Biosorption Of Chromium ( VI ) By Different Natural Biomasses

Cr (VI) is a toxic metal, which belongs to the list of priority pollutants due to its mutagenic and carcinogenic properties, defined by the US EPA. Contamination with Cr (VI) comes from electroplating, leather tanning, textile dyeing and metal finishing industries. Recently, a variety of low cost materials has been studied for their ability to remove this metal from aqueous solution with promising results. We studied the Cr (VI) removal capacity in aqueous solution by different natural biomasses, using the diphenylcarbazide method to evaluate the metal concentration in solution and obtaining the highest biosorption of the metal (50 mg/L). It was found that a pH for 1.0, temperature of 60°C, and 5 g of natural biomass, were the optimum conditions of the experiment. In addition, the natural biomasses showed good removal capacity of 1.0 g/L of the metal, at 28 o C 60 o C, and removed efficiently the metal of earth and water contaminated naturally. Keywords—Chromium (VI), Removal, Natural Biomasses, Detoxification
of Climate The Influence of Volcanic Eruptions on the Climate of South America during the Last Millennium

Abstract: Currently, little is known on how volcanic eruptions impact large-scale climate phenomena such as paleo-ITCZ position or South American Summer Monsoon behavior. In this paper, an analysis of observations and model simulations is employed to assess the influence of large volcanic eruptions on the climate of South America. This problem is considered both for historically recent volcanic episodes, for which more comprehensive global observations exist, as well as reconstructed volcanic events for the period 850 C.E. to present that are incorporated into the NASA GISS ModelE2-R simulation of the Last Millennium. An advantage of this model is its ability to explicitly track water isotopologues throughout the hydrologic cycle, to predict the anticipated isotopic imprint following a large eruption, and to remove a degree of uncertainty when comparing the GISS simulations to paleoclimate proxy archives.
Assessment removal of tritium radionuclide from liquid waste using sequential ion exchange resin

Tritium (3H) readily combines with oxygen to form water, so its behavior in aqueous systems is controlled by hydro logic processes and it migrates at essentially the same velocity as surface and ground water. In this study removal of tritium from radioactive aqueous solution by using a strongly acidic resin (KU-2) and weakly basic resin (AN-31) by batch and column technique was investigated. Batch studies were performed to estimate the effect of pH, contact time and resin weight in the removal process as well as desorption process. The optimum pH was found to be 7.8. The maximum uptake was reached within one hour and the equilibrium was reached within 1.5 h. Desorption of radioactive tritium was achieved using 3 M HNO3 and 2 M NaOH. The removal of tritium from liquid radioactive waste using the sequential cationic and anionic columns exchangers that are being used in Egyptian liquid radioactive waste treatment plant was applied. The obtained purified water reaches the permissible level to save our environment. Finally, results indicate that KU-2 resin is an efficient ion exchanger for the removal of 3H from aqueous solution.
THE INFLUENCE OF FATTENERS DRY AND LIQUID DIET ON SLAUGHTER TRAITS OF CARCASS

The study was conducted on 700 fattening pigs, three breed half blood with Duroc as a terminal breed ((Large White x Landrace) x Duroc). The pigs were divided into the two groups according to diet: dry and liquid nutrition. Each group consisted of 350 fattening pigs and used the same feed mixtures in prefattening (CP-3) and fattening (ST). During the period from 24.8 to 60kg they were fed with a CP-3, a crude protein content of 16.37%. During the period from 60kg until the end they were fed with ST, a crude protein content of 15.3%. Muscle tissue processed half-carcasses in slaughterhouses were determined by a device that determines the value of S (fat thickness) and M (muscle thickness) using "method one point. " Fat thickness skin in mm, measured 7 cm lateral to the central (median) cutting, in the amount between the second and third ribs of the tail. The thickness of the muscle in mm was measured at the same place as the thickness of the bacon. The results show that the fatling fed dry food had significantly higher carcass weight (80.41: 78.51 kg, p<0.05), backfat thickness (16.55: 15.31 mm, p<0.05), weight (muscle 55.80: 53.82, p<0.05), but a lower percentage of meat (56.6: 57.3, p<0.05) as compared to pigs fed liquid food. In finishing pigs fed dry food, between carcass weight and backfat thickness and muscle thickness a positive and significant correlation (0.4267 and 0.4290, p<0.05) was found and between carcass weight and lean meat a significant negative correlation (-0. 4236 and p<0.05). Between backfat thickness and lean meat in the carcass a negative and significant correlation (-0.8534, p<0.05) was found and between muscle thickness and lean meat a positive and significant correlation (0.2857, p<0.05). In finishing pigs fed liquid food, between carcass weight and backfat thickness and muscle thickness a positive and significant correlation (0.1800 and 0.3705, p<0.05) was found and between carcass weight and lean meat a significant negative correlation (-0. 2178; p <0.05). Between backfat thickness and percentage of meat in the carcass negative and significant correlation (0.8692, p<0.05) was found and between muscle thickness and lean meat a positive and significant correlation (0.3168, p<0.05).
Search Strategies for External Knowledge and Environmental Innovation : An Analysis of large French Manufacturing Firms

Although the antecedents of environmental innovation and the impact of openness on technological innovation have been well studied, the impact of firm? s openness on environmental innovation remains largely unknown. We here study the impact of three main dimensions of openness R&D acquiring, R&D sharing and external information sourcing ? on four types of environmental innovation. Results provide evidence of a positive impact of inbound innovation acquiring in all types of environmental innovation while R&D cooperation only enhances the adoption of environmental processes, i.e. cleaner technologies in the production stage of the firms. Regarding inbound innovation sourcing, market sources of information stemming from customers, suppliers or competitors, are positively and significantly associated to firms involvement in green innovative products and processes at all levels (production and end user stages) while scientific information sources (institutional) and publicly available information sources do not influence on the introduction of environmental innovations. Furthermore, we find that the combination of inbound innovation acquiring mode and internal R&D disincentives all types of EI considering the moderating role of absorptive capacity leverage at the firm-level. Significant implications can be drawn in terms of public policy, considering the importance of environmental innovation strategies for the sustainable development of our nations Jelcodes:Q55,O32 1 Search Strategies for External Knowledge and Environmental Innovation: An Analysis of large French Manufacturing Firms
Manuscript Number: bg-2019-132

Received and published: 5 June 2019 Ma et al. investigated the relationship between N2O production and spatial distribution of AOA and AOB along a salinity gradient in the Pearl River Estuary, China by using qPCR, chemical analysis and in situ incubation experiment. Data are well analyzed and presented. However, the manuscript’s structure should be modified because the some results were presented in the discussion section, and some conclusions needs to be rephrased because the main findings in this study were mainly based on the correlation analysis OR statistical analysis (e.g., between N2O production and the abundance of functional genes), which can’t provide a solid support for a causal relationship between microbial contributors and N2O production. Response: Many thanks for the reviewer’s comments. We moved the results pointed out by the reviewer into the Discussion section. We also revised some conclusion sentences with the appropriate tone according to the reviewer’s suggestions.
Pérez SIMULTANEOUS REMOVAL OF DISSOLVED ORGANIC MATTER , Microcystis aeruginosa , AND MICROCYSTIN-LR BY PRE-OXIDATION AND COAGULATION-FLOCCULATION

The aim of this work is to assess the effect of the presence of Microcystis aeruginosa (MA) and microcystin-LR (MC-LR) on the removal of dissolved organic matter (DOM) by coagulation-flocculation operated at optimal conditions. Also, the effect of pre-oxidation with NaOCl on the simultaneous removal of MA, MC-LR, and DOM was studied, using the same processes and conditions. The water used in the experimental tests was prepared with distilled water, strains of MA, microcystin-LR standards, and model compounds of DOM. All trials were carried out in a jar test equipment applying two designs: a fractional factorial design to identify those variables with significant influence, and a response surface to determine the optimal operational conditions for each of the evaluated processes. Results show that the simultaneous presence of MA and MC-LR reduce until 32.25% the DOM removal, because they were competitors for the coagulant. The main effect was associated to MA due to its physicochemical characteristics and its major concentration. The pre-oxidant dose did not have a significant influence on the removal of MA, MC-LR and DOM since the contact time used in the tests was very short.
Prehospital whole blood resuscitation prevents coagulopathy and improves acid–base status at hospital arrival in a nonhuman primate hemorrhagic shock model

Hemorrhage remains the primary cause of preventable death in civilian and military trauma. The Committee on Tactical Combat Casualty Care recommends prehospital (PH) resuscitation with whole blood (WB). However, 6% hetastarch in lactated electrolyte (HEX) and crystalloids are more commonly available and used for PH resuscitation in military and civilian environments, respectively. The mechanistic benefits of PH WB resuscitation have not been well studied and remain to be elucidated.
PERFORMNCE IN TERTIARY INSTITUTIONS IN WEST NILE SUB REGION OF UGANDA Epiphany

The study aimed to establish how institutional legal environment affects performance in public procurement in tertiary institutions in West Nile sub region of Uganda. A cross-sectional study design was used. Both quantitative and qualitative approaches were adopted in the study. This study targeted a sample of 122 respondents. Simple random sampling technique was used to select sample amongst the user departments’ staff. Purposive sampling technique was used to select the Accounting Officer and Contract Committee members. Quantitative data analysis mainly consisted of descriptive statistics (frequencies and percentages) and inferential statistics (Spearman Rank Order Correlation). Findings revealed an insignificantly very weak positive correlation ( rho = .065) between institutional legal framework and procurement performance. Thus, it was concluded that institutional legal environment, measured in terms of procurement legislations and the Procurement regulations, significantly affected performance in public procurement in tertiary institutions in West Nile sub region of Uganda. It is recommended that tertiary institutions in West Nile sub region of Uganda should focus on other institutional dynamics like institutional human capacity, institutional culture, institutional politics and institutional ethical values, but not on institutional legal environment since the correlation was very weak, in order to improve performance in public procurement in tertiary institutions in the sub region.
Adapting to Continuously Shifting Domains

Problem • Adapting from one single source to one single target is limiting • Incremental adaptation alone cannot recover good performance on past domains • Goal: adapt between continuously shifting domains, while avoiding catastrophic forgetting Standard domain adaptation • Source domain S, with images XS and labels YS drawn from pS(x,y) • Target domain T, with images XT unlabeled drawn from pT(x,y) • Minimize discrepancy between distributions by learning source and target representations, Ms and Mt, and classifier C Solution: incrementally adapt to new domains with a replay loss to maintain performance on past domains
University of Dundee PAWS 1 controls Wnt signalling through association with casein kinase 1

The BMP and Wnt signalling pathways determine axis specification during embryonic development. Our previous work has shown that PAWS1 (also known as FAM83G) interacts with SMAD1 and modulates BMP signalling. Here, surprisingly, we show that overexpression of PAWS1 in Xenopus embryos activates Wnt signalling and causes complete axis duplication. Consistent with these observations in Xenopus, Wnt signalling is diminished in U2OS osteosarcoma cells lacking PAWS1, while BMP signalling is unaffected. We show that PAWS1 interacts and co-localises with the a isoform of casein kinase 1 (CK1), and that PAWS1 mutations incapable of binding CK1 fail both to activate Wnt signalling and to elicit axis duplication in Xenopus embryos.
The Influence of Tropical Peat-Swamp Forest Edge Effects on Fruit Feeding Butterflies in the Sabangau Forest , Kalimantan

It is widely understood that the link between an organism and the complex transition between habitat boundaries is an idea that is relatively poorly understood due to the multiple biotic and abiotic influences that can affect said organism. To study this phenomenon in this particular investigation, frugivorous butterflies were used as an indicator to examine the possible edge effects found at a tropical peat swamp forest margin in the Sabangau Forest, Kalimantan. In collaboration with OuTrop (The Orangutan Tropical Peatland Project), Nymphalidae butterfly species were systematically surveyed at varying intervals from the forest periphery to observe whether species abundance, diversity and behaviour was influenced by the proximity to the edge, and whether there was a specific interval or ‘edge effect line’ where these impacts discontinued. By observing the findings it became clear that the overall abundance and distribution of some individual species do appear to be reduced closer to the boundary of the ecosystem, while unexpected aspects such as bait removal and predation are also evident within the study area. Despite the fact that some variables (such as species diversity) did not appear to be heavily influenced by the margin, in general this study suggests that edge effects are evident in this region of the ecosystem when frugivorous butterflies are concerned. Two possible intervals where a theoretical edge effect line could be found are also suggested here, however due to the impact of seasonality and catchment of investigation, further research over a greater distance and time period is needed in this region to fully comprehend how these invertebrates react to the influence of the forest edge.
RESPONSE OF SOME PLANT SPECIES TOWARDS THE ALLELOPATHY OF TWO TYPES OF CHICKPEA ( CICER ARIETINUM L . ) SEED EXTRACTS

The investigation was planned to study the chemical composition and allelopathic consequence of two types of chickpea against three weeds of the chickpea crop by using ethanolic extracts. The experiment was carried out in the University of Sulaimani, College of Agricultural Sciences, Sulaimani, Iraq. The extracts of two types, kabuli and black desi seeds, were analyzed by GC/MS, showing that the main constituents of eugenol (86.35%), beta caryophyllene (6.56%) and caryophyllene oxide (5.24%) for black desi seeds and eugenol (89.67%) and methoxy acetic acid, 3-tridecyl ester (3.47%) for kabuli seeds. The results showed that all seed extracts displayed significant allelopathic impact, whilst, the powerful of allelopathy of two types of chickpea differ from species to species of weeds. Based on the outcomes, the kabuli seed ethanolic extract showed the maximum degree of seed germination percentage inhibition of all plant species. The extracts acquired from the two types of chickpea caused significant reduction in radical and shoot length of all plant species. Based on the consequences, it can be determined that chickpea types exhibited good allelopathic potential that may be utilized in future as bio-herbicide screening program to launch in the market.
Identification of aberrantly methylated differentially expressed genes in age-related macular degeneration

Abstract DNA methylation plays a significant role in many diseases. Age-related macular degeneration (AMD) is a leading cause of vision loss for people aged 50 years and above, but the etiology and pathogenesis are largely unknown. This study aimed to identify the aberrantly methylated differentially expressed genes (DEGs) in AMD and predict the related pathways on the basis of public data. Aberrant methylation can influence the functions of key genes by altering their expression. Here, we found out DEGs by overlapping public microarray data (GSE29801 and GSE102952). Functional and enrichment analyses of selected genes were performed using the DAVID database. Subsequently, protein–protein interaction (PPI) networks were constructed by using STRING and visualized in cytoscape to determine hub genes. Finally, we collected AMD patients’ blood samples to identify the methylation statuses of these hub genes by using methylated DNA immunoprecipitation. In total, 156 hypermethylation-low expression genes and 127 hypomethylation-high expression genes were predicted. The hypermethylation-low expression genes were enriched in biological processes of response to cardiac conduction, ATP binding, and cell–cell junction assembly. The top 5 hub genes of the PPI network were HSP90AA1, HSPA1L, HSPE1, HSP90B1, and NOP56. Meanwhile, the hypomethylation-high expression genes were enriched in the biological processes of response to positive regulation of the MAPK cascade, actin cytoskeleton reorganization, dentate gyrus development, and cell migration. The top 5 hub genes of this PPI network were PIK3R1, EZR, IGF2, SLC2A1, and CDKN1C. Moreover, the methylation statuses of NOP56, EZR, IGF2, SLC2A1, CDKN1C were confirmed to be altered in the blood of AMD patients. This study indicated possible aberrantly methylated DEGs and differentially expressed pathways in AMD by bioinformatics analysis, providing novel insights for unraveling the pathogenesis of AMD. Hub genes, including NOP56, EZR, IGF2, SLC2A1, CDKN1C, might serve as aberrant methylation-based candidate biomarkers for AMD in future applications.
ALTITUDINAL GRADIENTS AND FOREST EDGE EFFECT ON SOIL ORGANIC CARBON IN CHINESE FIR ( CUNNINGHAMIA LANCEOLATA ) : A STUDY FROM SOUTHEASTERN CHINA

In forest ecosystems, soil organic matter facilitates carbon sequestration and serves as a sink for atmospheric CO2. Carbon in forest soils plays an important role in mitigating global climate change. Soil carbon density was measured at three depths (0-20, 20-40, and 40-60 cm) in four different elevation classes sites at the forest exterior and forest interior in the sub-tropical forests of southeastern China. Results showed that soil organic carbon (SOC) varied between 46.48 and 83.12 Mg ha at forest exterior and 50.18 and 90.68 Mg ha at forest interior in different elevation classes. A significant increasing trend in soil organic carbon was found with an increase in elevation at both forest exterior and forest interior. Similarly, a positive correlation between soil organic carbon and elevation was observed at forest exterior (R = 0.87, P = 0.0001) and forest interior (R = 0.93, P = 0.0001). The percentages of soil carbon at 0-20, 20-40, and 40-60 cm depths at forest exterior and forest interior were 47.24-52.76, 47.23-52.77, and 46.95-53.05% respectively. Soil bulk density was directly related to soil depth and inversely related to elevation at forest exterior and forest interior. Overall the mean SOC at forest exterior and forest interior was 60.83 Mg ha and 68.20 Mg ha respectively. The study showed that there is a 5.7% difference in soil carbon density between forest exterior and forest interior which highlights the fact that ignoring edge effects may lead to overestimation of soil carbon density. Therefore, we suggest the establishment of permanent sample plots sites at the forest exterior and forest interior and recommend regular periodic surveys of soil for accurate forest soil carbon measurement.
Does Good Corporate Governance Reduce Credit Risk

How does corporate governance affect debt holders? On the one hand, effective corporate governance ensures sustainable management performance, efficient allocation of resources, sound investment strategy and reliable reporting. Altogether these factors improve companies’ financial health and creditworthiness, reduce information asymmetry between the firm and outside investors, reduce default risk and ultimately benefit the debt holders. On the other hand, strong shareholder-oriented corporate governance might ignore the interests of creditors. Especially on the verge of financial distress, strategies that maximize shareholders’ outcome may lead to making value-destroying decisions, and thus harm debt holders. Although creditors are priority claimants in cases of company’s financial distress, they may still be exploited, as highly leveraged firms on the verge of bankruptcy have strong incentives to gamble with lender’s money in favor of the stockholders. Furthermore, while strong shareholder rights and a possibility of a takeover are a recognised remedy to managerial opportunism, changes in corporate ownership are not always beneficial for lenders. Thus, the effect of governance quality in terms of antitakeover provisions and shareholder rights on debt holders is equivocal. The purpose of this study is to statistically evaluate the effect of governance quality on credit risk, approximated by the CGQ Score and Moody’s credit ratings respectively. Both parametric and non-parametric statistical methods are employed and produce similar results: Our setting did not reveal any significant correlation between the two characteristics. This result is consistent with mixed evidence on shareholder – debt holder relationship found in the literature. This relationship is complex and equivocal and depends on the perspective of analysis. In our comprehensive approach positive and negative effects of corporate governance on credit risk might cancel each other to produce zero net effect in our setting.
Open innovation and NIH syndrome through the lens of transaction cost economics

Open innovation has long been considered as a better alternative to closed innovation when there are barriers to the latter, especially in conditions of scarce financial resources and knowledge. However, some recent studies, e.g. by Drechsler and Natter (2012) and Kurtmollaiev and Pedersen (2012), find that firms do not open up their innovation process to fill knowledge gaps, which indicates so-called "not-invented-here" (NIH) syndrome. In this theoretical paper the transaction cost economics is used to examine the phenomena of open innovation and NIH syndrome. Based on the developments of transaction cost perspective on inter-organizational (inter-firm) relationships, the specifics of governance structure for open innovation are described.