Miracle-dz/UniFAR-FTUs huggingface dataset:
Siriusly, a newly identified intermediate-age Milky Way stellar cluster: a spectroscopic study of Gaia 1

We confirm the reality of the recently discovered Milky Way stellar cluster Gaia 1 using spectra acquired with the HERMES and AAOmega spectrographs of the Anglo-Australian Telescope. This cluster had been previously undiscovered due to its close angular proximity to Sirius, the brightest star in the sky at visual wavelengths. Our observations identified 41 cluster members, and yielded an overall metallicity of [{Fe}/{H}]=-0.13± 0.13 and barycentric radial velocity of vr = 58.30 ± 0.22 km s-1. These kinematics provide a dynamical mass estimate of 12.9^{+4.6}_{-3.9}× 10^3 M_{⊙}. Isochrone fits to Gaia, 2MASS, and Pan-STARRS1 photometry indicate that Gaia 1 is an intermediate age (˜3 Gyr) stellar cluster. Combining the spatial and kinematic data we calculate Gaia 1 has a circular orbit with a radius of about 12 kpc, but with a large out of plane motion: z_{max}=1.1^{+0.4}_{-0.3} kpc. Clusters with such orbits are unlikely to survive long due to the number of plane passages they would experience.
Sweet orange trees grafted on selected rootstocks fertilized with nitrogen, phosphorus and potassium

The majority of citrus trees in Brazil are grafted on 'Rangpur lime' (Citrus limonia Osb.) rootstock. Despite its good horticultural performance, search for disease tolerant rootstock varieties to improve yield and longevity of citrus groves has increased. The objective of this work was to evaluate yield efficiency of sweet oranges on different rootstocks fertilized with N, P, and potassium. Tree growth was affected by rootstock varieties; trees on 'Swingle' citrumelo (Poncirus trifoliata (L.) Raf. × C. paradisi Macf. ) presented the smallest canopy (13.3 m 3 in the fifth year after tree planting) compared to those on 'Rangpur lime' and 'Cleopatra' mandarin (C. reshni (Hayata) hort. ex Tanaka) grown on the same grove. Although it was observed an overall positive relationship between canopy volume and fruit yield (R 2 = 0.95**), yield efficiency (kg m -3 ) was affected by rootstocks, which demonstrated 'Rangpur lime' superiority in relation to Cleopatra. Growth of citrus trees younger than 5-yr-old might be improved by K fertilization rates greater than currently recommended in Brazil, in soils with low K and subjected to nutrient leaching losses.
Copeptin Levels Do Not Correlate With Cross-Clamping Time in Patients Undergoing Carotid Endarterectomy Under General Anesthesia

Copeptin is a sensitive and more stable surrogate marker for arginine vasopressin. In this study, we evaluated copeptin levels in carotid endarterectomy (CEA) patients, perioperatively, to determine whether copeptin levels can be related to carotid artery cross clamping (CC) time and to postoperative neurological outcomes. Copeptin, interleukin 6, C-reactive protein, cortisol, and brain natriuretic peptide were measured preoperatively (T1) and 3 hours postoperatively (T3) as well as intraoperatively (T2). We recruited 77 patients. Values of copeptin rose gradually over the observed times: T1 = 7.9 (6.4-9.6), T2 = 12.6 (9.3-16.8), and T3 = 72.3 (49.1-111.2) pmol/L. There was a significant difference for repeated measurement (P = .000, P = .000, and P = .000). Duration of carotid artery CC during CEA does not affect postoperative copeptin level (CC ≤ 13 minutes: 106.8 ± 93.6 pmol/L, CC > 13 minutes: 96.7 ± 89.1 pmol/L; P = .634). Preoperative copeptin level was significantly higher in patients with ulcerated plaque morphology. Activation of the stress axis in patients undergoing CEA results in copeptin elevation. Duration of CC during CEA does not affect postoperative copeptin levels.
Adipokine Profile in Patients with Type 2 Diabetes Depends on Degree of Obesity

Background The fast pace of life, promoting fast food consumption and low physical activity, has resulted in obesity and/or diabetes as being serious social problems. The aim of the present study was to evaluate concentrations of selected adipokines (leptin, adiponectin, resistin, and visfatin) and to assess the leptin/adiponectin ratio in plasma of type 2 diabetes (T2D) patients in relation to degree of obesity. Material/Methods The study comprised 92 T2D subjects divided into 4 groups according to BMI value – I (normal body weight), II (overweight), III (obesity), and IV (severe obesity) – and 20 healthy volunteers (control group). Each group was divided into male and female subgroups. Plasma concentrations of adipokines were determined by enzyme-linked immunosorbent assay. Results In women, leptin concentration was significantly higher in group IV, whereas in men it was higher in groups III and IV than in the control group and groups I and II. Irrespective of sex, a significant decrease in adiponectin level was observed in group III vs. control. There was no significant difference in resistin levels. In women visfatin was markedly enhanced in group III, whereas in men in groups II, III and IV vs. control. Leptin/adiponectin ratio was increased in groups III and IV vs. control in women, whereas in men vs. both control and group I. Conclusions The obese type 2 diabetic patients presented a disturbed adipokine profile, which seems to be an important link between obesity and T2D. The future studies concerning the question if regulating of adipokines’ concentrations could be a promising approach for managing metabolic disorders seem to be well-grounded.
Association Between a Woman's Age at First Birth and High Blood Pressure

AbstractThe aim of this article is to determine whether the age of a woman at first birth is associated with treatment for high blood pressure (HBP) later in life.Baseline data for 62,914 women were sourced from the “45 and Up Study,” an observational cohort study of healthy aging in Australia. These women had given first birth between the ages of 18 and 45 years. Odds ratios and 95% confidence intervals for the association between age that a woman gave first birth and treatment for HBP were estimated using logistic regression. Data were stratified by current age (<60 and ≥60 years) and adjusted for demographic and lifestyle factors.There was a significant association between age at first birth and present day HBP. Older age at first birth was associated with a lower likelihood of HBP in women aged 25 to <35 years and 35 to 45 years at first birth (in women currently <60 years) and 35 to 45 years at first birth (in women currently ≥60 years of age), compared with women aged 18 to <25 years at first birth, adjusting for demographic and lifestyle factors.Women who were older when they gave first birth had lower odds of treatment for HBP compared with women who were younger when they gave birth to their first child. The contribution of a woman's pregnancy history, including her age at first birth, should be discussed with a patient when assessing her risk of HBP.
Recycling behaviour of householders living in multicultural urban area: a case study of Järva, Stockholm, Sweden

The recycling behaviour of multicultural householders was investigated in the urban area of Järva, northwest Stockholm, Sweden, which is home to a significant proportion of immigrants from different parts of the world. Different ethnic minorities currently make up an important proportion of the urban population in Sweden, but little is known about their recycling behaviour and attitudes. Using quantitative (questionnaire) and qualitative (interviews) methodology, possible determinants of recycling behaviour were investigated among Järva householders. It was found that attitude toward the importance of recycling had a positive correlation and was the main determinant of recycling behaviour among these householders. In contrast, environmental concern, satisfaction with the facilities provided, recycling confidence, community identity and socio-demographical factors showed no correlation with their recycling behaviour. Other results of the study indicated a need to investigate the specific behaviour of multicultural householders regarding source-separated collection and the recycling of hazardous, electronic and bulky wastes.
Inhibition of motor unit firing during experimental muscle pain in humans

Electromyographic activity was recorded in the masseter muscle to investigate whether the firing characteristics of single motor units (SMUs) were affected by muscle pain. Capsaicin was injected into the masseter to induce pain. The interspike interval (ISI) and recruitment threshold of SMUs were measured while subjects performed isometric contractions at 5, 7.5, 10, 15, and 20% of maximum voluntary contraction. All subjects were able to maintain a stable isometric force during pain, but the mean ISI was significantly increased without changing the recruitment threshold. In all the experimental conditions, the firing frequency increased with increasing force, and SMUs recruited at low force fired at higher rates for all force levels. These results suggest that acute stimulation of nociceptive muscle afferents inhibits SMU activity without changing recruitment order in the homonymous muscle. © 2000 John Wiley & Sons, Inc. Muscle Nerve 23: 1219–1226, 2000.
Effect of Organisation Culture on Employee Performance in Non Govermental Organizations

Culture may have a big influence on the performance of all organizations worldwide. This is a practice that cannot just be assumed as it has both positive and negative effects as far as performance is concerned. It is more serious when it comes to non-Governmental organizations, since in most cases they involve international Governments. The main focus of the study was the non-governmental organizations in Kenya with a specific focus on World Vision Kenya. The specific objectives of the study were to establish the link between competitive culture and performance in Non-Governmental Organizations, to explore the effect of entrepreneurial culture on performance in NonGovernmental Organizations, to assess the level of bureaucratic culture and its influence on overall performance in NonGovernmental Organizations, to examine the influence of consensual culture on performance in Non-Governmental Organizations, and finally to identify the preferred cultural integrations in Non-Governmental Organizations in Kenya. The research design adopted for this study was a descriptive survey in which the research seeks to collect data from a target population of employees working in World Vision Kenya, using questionnaires to determine the correlation between organization culture and employee performance. The target population comprised of 960 employees in World Vision Kenya, a sample size of 484 was taken from the overall target population. Data was analyzed qualitatively and quantitatively and through use of statistical package for social scientists (SPSS). The study concluded that organization culture has a great influence on performance as it dictates how things are done, organization‟s philosophy, work environment, performance targets and organizations stability. At World Vision Kenya there is an integration of cultures ranging from competitive culture, entrepreneurial culture, bureaucratic culture and consensual culture. Of the four cultures, employees prefer integration to consensual and entrepreneurial or competitive and entrepreneurialcultures. This owes to the fact that employees seek a work environment that maximizes their ability to be innovative, creative, and independent of micro-management, cohesion with fellow colleagues among others.
Antimicrobial potential of Spondias mombin, croton zambesicus and Zygotritonia crocea

The antimicrobial activity of Spondias mombin, Croton zambesicus and Zygotritonia crocea sourced from herbalists through an ethnobotanical survey of Egbado‐South in Ogun State in Nigeria is reported. The extracts of the leaf of Spondias mombin and the stem bark of Croton zambesicus exhibited wide spectrum antibacterial effects comparable to those of ampicillin and gentamycin. The antifungal effect of extracts of Zygotritonia crocea and Croton zambesicus were comparable to those of tioconazole. There is justification for the use of these little studied medicinal plants as antiinfective agents in traditional medicine. Copyright © 1999 John Wiley & Sons, Ltd.
Analysis of the murine Hox‐2.7 gene: conserved alternative transcripts with differential distributions in the nervous system and the potential for shared regulatory regions.

In this study we have investigated the organization and regulation of the mouse Hox‐2.7 gene. There are several alternative transcripts some of which are conserved between mouse and humans. By Northern and in situ analysis we are able to identify at least three types of transcripts which are different in size and splicing pattern and have distinctly different boundaries of expression in the nervous system. One subset of the endogenous transcripts has a boundary of expression that corresponds to the adjacent Hox‐2.8 gene instead of Hox‐2.7. In another type of transcript there is an alternative reading frame which predicts a protein that has homology to an enzyme ATPase and suggests that a non‐homeobox containing gene may be located in the Hox‐2 cluster. A Hox‐2.7‐lacZ transgene is expressed in a similar pattern to the endogenous gene in that spatially‐restricted domains of expression are seen in the branchial arches, neural tube, paraxial mesoderm (somites), cranial ganglia, neural crest and gut. However, the anterior boundaries of transgene expression only correspond to the subset of Hox‐2.7 transcripts which map to the Hox‐2.8 boundary. The proximity of a Hox‐2.7 promoter to regions which regulate the adjacent Hox‐2.6 gene and the expression of transgenic and endogenous transcripts in a Hox‐2.8 pattern, suggest that regulatory elements may be shared by neighbouring genes to establish the complete expression pattern.
Linking large administrative databases: a method for conducting emergency medical services cohort studies using existing data.

OBJECTIVE To evaluate probabilistic matching for linking a cohort of cardiac arrest (CA) patients identified in the Metro Toronto Ambulance (MTA) database in Toronto, Ontario, Canada, to their appropriate record in either the Vital Statistics Information System (VSIS) or the Canadian Institute of Health Information (CIHI) databases and thus establish their clinical outcomes. METHODS A linkage of a large administrative database was performed. A cohort of patients who suffered an out-of-hospital CA during the calendar years 1988-1993 was identified. To determine the patients' outcomes, the cohort was probabilistically linked to patient records in the VSIS and CIHI databases. Identifying variables used during the process of linking records included: names (first and last); New York State Identification and Intelligence System (NYSIIS) code; date of event; date of death; city; admitting hospital number; mode of admission to hospital; age; and sex. RESULTS A cohort of 7,079 CA patients was identified from the MTA database; 6,448 (91%) patients were accurately linked to records in 1 of the 2 outcome databases (CIHI, VSIS). Missing data for > or = 1 of the linking variables were responsible for unlinked records. Using these longitudinal data, it was possible to determine the number of patients surviving their out-of-hospital CAs to be admitted to hospital (n = 833) (16%). No differences in survival rates (p = 0.06) or median lengths of hospital stay among the survivors (p = 0.15) were observed between admitting hospitals. CONCLUSIONS Probabilistic matching is an effective method by which researchers can use existing administrative data to determine outcomes of population cohorts. This is especially valuable in situations where controlled intervention studies are not feasible or may be inappropriate. In this analysis, in-hospital management of admitted CA patients, as determined by hospital-specific survival rates and length of stay, suggests no measurable differences in the care provided to these patients by hospitals in Toronto.
HIV/AIDS stigma attitudes among educators in KwaZulu-Natal, South Africa.

BACKGROUND One hundred and twenty educators from KwaZulu-Natal, South Africa, underwent HIV/AIDS training. The educators were surveyed about their attitudes toward people with HIV. METHODS The educators completed self-administered survey questionnaires both before and after 2 interventions. Measures included demographic characteristics, teachers' knowledge about HIV/AIDS, self-efficacy in handling HIV/AIDS situations, and attitudes (stigma and otherwise) toward HIV-related issues. The first intervention was a CD-ROM and the second intervention involved educators receiving a 2-day workshop on HIV transmission, risk factors, and actions that educators should know and undertake. The first step entailed testing the stigma instrument for its internal consistency and developing and testing potential subscales from the instrument. The second step entailed testing for the statistical associations between stigma (as measured by the stigma instrument and its subscales) and various demographic and HIV knowledge-related variables. RESULTS The overall stigma scale had a Cronbach α coefficient of . 66. Educators in the workshop generally had lower baseline levels of stigma than those in the CD-ROM intervention. Following both interventions, the stigma levels of both groups of educators were significantly reduced. Improvements in the general knowledge about HIV as a disease and in the specific knowledge about HIV transmission risks were both statistically significantly associated with reductions in stigma attitudes, having controlled for educators' baseline stigma levels and demographic profiles. CONCLUSIONS The levels of teachers' stigma attitudes were statistically significantly lower after both types of HIV/AIDS training and were also statistically significantly associated with improvements in HIV knowledge.
Soluble TNF‐α but not transmembrane TNF‐α sensitizes T cells for enhanced activation‐induced cell death

In addition to its proinflammatory effects, TNF‐α exhibits immunosuppression. Here, we compared the capacities of transmembrane TNF‐α (tmTNF) and soluble TNF‐α (sTNF) in regulating expansion of activated T cells by apoptosis. Splenic CD4+ T cells from wtTNF, TNF‐α‐deficient (TNF−/−) and TNF−/− mice expressing a non‐cleavable mutant tmTNF showed comparable proliferation rates upon TCR‐mediated stimulation. Activation‐induced cell death (AICD), however, was significantly attenuated in tmTNF and TNF−/−, compared with wtTNF CD4+ T cells. Addition of sTNF during initial priming was sufficient to enhance susceptibility to AICD in tmTNF and TNF−/− CD4+ T cells to levels seen in wtTNF CD4+ T cells, whereas addition of sTNF only during restimulation failed to enhance AICD. sTNF‐induced, enhanced susceptibility to AICD was dependent on both TNF receptors. The reduced susceptibility of tmTNF CD4+ T cells for AICD was also evident in an in vivo model of adoptively transferred CD4+ T‐cell‐mediated colonic inflammation. Hence, the presence of sTNF during T‐cell priming may represent an important mechanism to sensitize activated T cells for apoptosis, thereby attenuating the extent and duration of T‐cell reactivities and subsequent T‐cell‐mediated, excessive inflammation.
Analysis of family resemblance. II. A linear model for familial correlation.

Wright [1] developed path analysis to describe familial correlation under a linear model. This remains its principal use, despite extension to nonfamilial data and interactive systems [2, 3]. His seminal paper on the intelligence quotient has been surprisingly neglected by human geneticists, perhaps because values had to be assumed for some unknown parameters [4]. Recently this indeterminacy was resolved by combining path analysis with the concept of an index and a theory of hypothesis testing [5]. In this form it appears to be a powerful tool to analyze family resemblance and group differences in man. Since our work depends on path analysis, which, like so much in population genetics, is the creation of Sewall Wright, we take pleasure in dedicating this paper to him.
Power-Normalized Cepstral Coefficients (PNCC) for robust speech recognition

This paper presents a new feature extraction algorithm called Power Normalized Cepstral Coefficients (PNCC) that is based on auditory processing. Major new features of PNCC processing include the use of a power-law nonlinearity that replaces the traditional log nonlinearity used in MFCC coefficients, a noise-suppression algorithm based on asymmetric filtering that suppress background excitation, and a module that accomplishes temporal masking. We also propose the use of medium-time power analysis, in which environmental parameters are estimated over a longer duration than is commonly used for speech, as well as frequency smoothing. Experimental results demonstrate that PNCC processing provides substantial improvements in recognition accuracy compared to MFCC and PLP processing for speech in the presence of various types of additive noise and in reverberant environments, with only slightly greater computational cost than conventional MFCC processing, and without degrading the recognition accuracy that is observed while training and testing using clean speech. PNCC processing also provides better recognition accuracy in noisy environments than techniques such as Vector Taylor Series (VTS) and the ETSI Advanced Front End (AFE) while requiring much less computation. We describe an implementation of PNCC using “on-line processing” that does not require future knowledge of the input.
Relationship of Phylogenetic Background, Biofilm Production, and Time to Detection of Growth in Blood Culture Vials with Clinical Variables and Prognosis Associated with Escherichia coli Bacteremia

ABSTRACT In patients with Escherichia coli bacteremia, data on the relationship of phylogenetic background, biofilm production, and degree of bacteremia with clinical variables and prognosis are scarce. During a 1-year period, all adults with bacteremia due to Escherichia coli diagnosed at a university center were enrolled. Determination of phylogenetic background, biofilm production, and genotyping was performed with all strains, and the time to positivity of blood culture vials was recorded. A total of 185 episodes of diverse-source E. coli bacteremia was analyzed. Strains of phylogroup D were predominant (52%). Phylogroup A isolates were associated with pneumonia and prior antibiotic intake, B1 with an abdominal source of infection, B2 with the absence of urological abnormalities, and D with urological abnormalities and age below 65 years. Resistance to antibiotics and no biofilm production were concentrated in phylogroup A strains. Biofilm production was not associated with any clinical variable. An immunocompromising condition (odds ratio [OR] = 5.01, 95% confidence interval [CI] = 1.4 to 17.9), peritonitis (OR = 17, 95% CI = 3.32 to 87), pneumonia (OR = 9.97, 95% CI = 1.96 to 50.6), and ≤7 h to bacteremia detection (OR = 4.37, 95% CI = 1.38 to 13.8) were the best predictors of a fatal outcome. Results from this study suggest that the distribution of phylogenetic backgrounds among E. coli strains involved in diverse-source bacteremia may be subject to geographical variation and that, in afflicted individuals, some high-risk sources, the patient's underlying condition, and the degree of bacteremia are more important than microbial factors in determining the outcome. Time to positivity of blood culture vials may be a variable of potential clinical impact.