Miracle-dz/UniFAR-FTUs huggingface dataset:
Influence of patient satisfaction through commitment to loyalty inpatient HOSPITALS Jayapura

The study was done at the Jayapura Public Hospital Area. The number of respondents was 294 patients. Variable measurement research done using multiple indicator, then analyzed using structural equation model (Structural Equation Modeling) Software with AMOS, and SPSS. Ver. 21. The findings of this study are: Patient satisfaction is positive and significant effect against the commitment of the Patient; Patient satisfaction and positive effect not significant Loyalty towards Patients;; The patient's commitment to a positive and significant effect against Patient Loyalty. Furthermore, satisfaction, confidence, and commitment are positioned as the mediation between the variable quality of service with loyalty. So, orisinilitas findings in these studies is variable commitment as mediation of service quality, customer satisfaction, loyalty and confidence. In General, the findings of this study provide strong support against the role of commitment required in building long term relationships and provide strong support for the mediation mechanism.
Review of Digital Watermarking Techniques

watermarking is delicate to various attacks in spatial domain, Hence in most of the watermarking technique's transform domain is used. This paper takes a survey of such digital watermarking techniques and methods like Discrete cosine transform (DCT), Singular value decomposition (SVD), SVD-DCT, DWT-SVD with different approaches along with their applications, advantages and disadvantages. Further future work and implementation plan is also mentioned in the paper. KeywordsDiscrete Wavelet transform (DWT), SVD
Cytosolic ionized Ca 2 1 modulates chemical hypoxia-induced hyperpermeability in intestinal epithelial monolayers

Unno, Naoki, Shozo Baba, and Mitchell P. Fink. Cytosolic ionized Ca21 modulates chemical hypoxia-induced hyperpermeability in intestinal epithelial monolayers. Am. J. Physiol. 274 (Gastrointest. Liver Physiol. 37): G700–G708, 1998. —We reported previously that ATP depletion induced by glycolytic inhibition or cellular hypoxia increases the permeability of intestinal epithelial monolayers [N. Unno, M. J. Menconi, A. L. Salzman, M. Smith, S. Hagen, Y. Ge, R. M. Ezzell, and M. P. Fink. Am. J. Physiol. 270 (Gastrointest. Liver Physiol. 33): G1010–G1021, 1996]. In the present study, we examined the effects of the Ca21 ionophore A-23187 or the intracellular ionized Ca21 concentration ([Ca]i) chelator 1,2-bis(2-aminophenoxy)ethane-N,N,N8,N8-tetraacetic acid (BAPTA)-AM on the permeability of enterocytic (T84) monolayers depleted of ATP by metabolic inhibition. Permeability was assessed by measuring transepithelial electrical resistance and the transepithelial flux of fluorescein sulfonic acid. Although neither A-23187 nor BAPTA-AM affected ATP depletion, A-23187 augmented, whereas BAPTA-AM ameliorated, chemical hypoxia-induced hyperpermeability. BAPTA-AM ameliorated chemical hypoxia-induced cytoskeletal derangements. Monolayers subjected to chemical hypoxia but incubated in a low (i.e., 100 μM) [Ca21] environment showed preservation of junctional integrity, whereas voltage-dependent Ca21 channel blockers (NiCl2 or verapamil) failed to ameliorate chemical hypoxia-induced hyperpermeability. ATP depletion induces hyperpermeability in intestinal epithelial monolayers via a [Ca]i-dependent mechanism. Increased [Ca]i under these conditions reflects leakage of Ca21 from the extracellular milieu via a mechanism unrelated to voltagedependent Ca21 channels.
Clinical outcome of 50 patients with malignant abdominal paragangliomas and malignant pheochromocytomas

Background: Tumors of the paraganglionic system represent a distinct, albeit uncommon, clinical entity characterized by catecholamine hypersecretion and hemodynamic instability; initial pathologic examination often cannot predict benign vs malignant behavior. An analysis of the clinical outcome of patients with known malignant tumors may serve to enhance the initial evaluation and therapeutic plan of all patients presenting with pheochromocytoma or paraganglioma. Methods: At the University of Texas M D Anderson Cancer Center, 30 patients with malignant abdominal paraganglioma and 20 patients with malignant pheochromocytoma were diagnosed between 1971 and 1995. Their medical records were reviewed with particular attention to clinical characteristics and disease outcome. Results: Among the 30 patients with paraganglioma, 73% were men, and 90% were younger than 50 years at the time of diagnosis. Sixteen patients have remained alive with persistent disease 0.2 to 25 years after initial diagnosis while eight patients died of their disease within 0.8 to 32 years. Regional recurrence and skeletal metastases were the most prominent events. Among the 20 patients with pheochromocytoma, 60% were men and 70% were younger than 50 years at the time of diagnosis. Ten patients have remained alive with persistent disease 0.8 to 20 years after initial diagnosis while five patients died of their disease within 1.5 to 39 years. Hypertension was a prominent presenting feature and regional recurrence was the most frequent pattern of treatment failure. Conclusions: Important clinical differences distinguish adrenal pheochromocytomas from extraadrenal, abdominal paragangliomas. Patients with paragangliomas are, as a group, younger men, more likely to have malignant lesions and a more aggressive clinical course. Patients with malignant pheochromocytomas usually present with hypertension, are somewhat older, and have less aggres
Cryogenic Blackbody Calibrations at the National Institute of Standards and Technology Low Background Infrared Calibration Facility

The Low Background Infrared Calibration Facility (LBIR) at the National Institute of Standards and Technology has been in operation for calibration measurements of the radiant power emitted from infrared radiation (IR) sources, such as cryogenic blackbodies, for more than 2 years. The IR sources are sent to NIST by customers from industry, government, and university laboratories. An absolute cryogenic radiometer is used as the standard detector to measure the total radiant power at its aperture. The low background is provided by a closed cycle helium refrigeration system that maintains the inner parts of the calibration chamber at 20 K. The radiance temperature of the blackbody is deduced from the measured power and compared with the blackbody temperature sensor data. The calibration procedures and data analysis are illustrated using the measurements of a typical blackbody.
Mapping of lymphatic filariasis in India

The derivation of detailed epidemiological maps, at the relevant spatial resolution, is being increasingly recognized as vital to the effective design and implementation of successful programmes for the control of parasites and their vectors. Geographical information systems (GIS) and a recently compiled database on the distribution of lymphatic filariasis in India have now been used to develop the first maps at district-level (i.e. the level at which control against this parasite will be enacted in India) of filariasis endemicity in this country. The derived maps indicate both the substantial extent as well as the marked variability in the geographical distribution of this disease in India. The causative infection and/or the symptomatic disease were detected in most (257) of the 289 districts surveyed up to 1995. Currently there may be up to 27.09 million microfilaraemics, 20.83 million cases of symptomatic filariasis, and about 429.32 million individuals potentially at risk of infection in the country. Probability mapping, based on data quantiles, clearly indicates that the risk of filarial infection in India is not constant throughout the country but exhibits strong regional trends. Filariasis in general may be a particular problem of the eastern half of the country. The results indicate the potentially vital role that GIS-based mapping approaches can play in the development of filariasis-control campaigns in India and elsewhere.
Magnification in endodontics: the use of the operating microscope.

(Figure 1) together with the power of ultrasonics and instruments for micro-endodontics are areas that have changed the face of endodontics. Until recently, endodontics was traditionally performed by hand with radiographic confirmation. To perform a root canal treatment often meant working inside a ‘black hole’ and many results were achieved by chance. Today, every challenge existing in the straight portion of the root canal system, even if located in the most apical part, can be easily seen and often solved under the microscope, with magnification and coaxial illumination. With the use of ultrasonics, the removal of posts, calcifications and broken instruments is faster, safer and easier. To locate missed canals or to negotiate calcified canals is more predictable using ultrasonic tips under the microscope. As far as new materials are concerned, recently Mineral Trioxide Aggregate (MTA) has become available. This is a revolutionary material, extremely biocompatible,
Active Surveillance for Carbapenem-Resistant Enterobacteriaceae Using Stool Specimens Submitted for Testing for Clostridium difficile

Active surveillance to identify asymptomatic carriers of carbapenem-resistant Enterobacteriaceae (CRE) is a recommended strategy for CRE control in healthcare facilities. Active surveillance using stool specimens tested for Clostridium difficile is a relatively low-cost strategy to detect CRE carriers. Further evaluation of this and other risk factor-based active surveillance strategies is warranted.
The effect of degenerative section of ganglionic axons on transmission through the ganglion

There is evidence that reflex conduction in the spinal cord is disturbed when the axons of the anterior horn cells are regenerating after division (Campbell, 1944; Downman, Eccles & McIntyre, 1953). There is also evidence of altered synaptic function in ganglia after degenerative section of postganglionic fibres (Acheson, 1952). Our attention was first drawn to this problem during an investigation of the pathways through the inferior mesenteric ganglion in the rabbit (Brown & Pascoe, 1952); we found that degenerative section of postganglionic trunks caused complete failure of synaptic transmission between preganglionic nerves and the cells with cut axons. We accordingly undertook a systematic investigation of the phenomenon, using other ganglionic systems in which the fibre connexions are less complex than in the inferior mesenteric. Our experiments have shown that the preganglionic nerve and its endings are unaffected, and that conduction in the proximal portion of the divided axon is substantially normal; the defect responsible for the failure of synaptic transmission lies in the soma of the neurones. Preliminary accounts of some of this work have appeared (Brown, McLennan & Pascoe, 1952a, b).
Reprogramming during epithelial to mesenchymal transition under the control of TGFβ

Epithelial-mesenchymal transition (EMT) refers to plastic changes in epithelial tissue architecture. Breast cancer stromal cells provide secreted molecules, such as transforming growth factor β (TGFβ), that promote EMT on tumor cells to facilitate breast cancer cell invasion, stemness and metastasis. TGFβ signaling is considered to be abnormal in the context of cancer development; however, TGFβ acting on breast cancer EMT resembles physiological signaling during embryonic development, when EMT generates or patterns new tissues. Interestingly, while EMT promotes metastatic fate, successful metastatic colonization seems to require the inverse process of mesenchymal-epithelial transition (MET). EMT and MET are interconnected in a time-dependent and tissue context-dependent manner and are coordinated by TGFβ, other extracellular proteins, intracellular signaling cascades, non-coding RNAs and chromatin-based molecular alterations. Research on breast cancer EMT/MET aims at delivering biomolecules that can be used diagnostically in cancer pathology and possibly provide ideas for how to improve breast cancer therapy.
Clinical Characteristics of Multiple Sclerosis in Kuwait: Data From the New MS Registry of Amiri Hospital

ABSTRACT Objectives: To study clinical characteristics of multiple sclerosis (MS) patients in Kuwait and to collect data on annual relapse rates and disability measures. Method: An MS Registry was created in Amiri Hospital. Demographic, clinical characteristics, and disability measures using Expanded Disability Status Scale (EDSS) score at last visit were collected. Results: Data from 218 patients formed the basis of the study cohort. Female to male ratio was 1.95. Mean age of onset of MS was 26.8 years. Seventy-eight percent had a relapsing–remitting course, 9.2% had secondary progressive course, and 2.8% had primary progressive course. The clinically isolated syndrome (CIS) group constituted 10.1%. The mean disease duration was 8 ± 7.2 years. Forty-five percent of patients had ≤5 years of disease duration, followed by 24.3% and 25.2% in the 5–10 and 10–20 years durations. Only 5.5% had MS for >20 years; 77.1% of patients had <1 relapse per year, while 22% had 1–2 relapses per year; 67.89% of patients had EDSS score <4, whereas 17.89% were found to have EDSS of ≥6. Summary: MS in Kuwait predominantly affects female. The mean age of onset and frequency of MS types are comparable to worldwide figures. The annual relapse rates and the EDSS scores were relatively low in our cohort.
The effect of interval training combined with thigh cuffs pressure on maximal and submaximal exercise performance

The purpose of the study was to investigate the effect of interval training combined with a thigh cuffs pressure of +90 mmHg on maximal and submaximal cycling performance. Twenty untrained individuals were assigned either to a control (CON) or to an experimental (CUFF) training group. Both groups trained 3 days per week for 6 weeks at the same relative intensity; each training session consisted of 2‐min work bout at 90% of : 2‐min active recovery bout at 50% of . An incremental exercise test to exhaustion, a 6‐min constant‐power test at 80% of (Sub80) and a maximal constant‐power test to exhaustion (TF150) were performed pre‐ and post‐training. Despite the unchanged , both groups significantly increased peak power output (CON: ∼12%, CUFF: ∼20%) that was accompanied by higher deoxygenation (ΔStO2) measured with near‐infrared muscle spectroscopy. These changes were more pronounced in the CUFF group. Moreover, both groups reduced during the Sub80 test without concomitant changes in ΔStO2. TF150 was enhanced in both groups. Thus, an interval exercise training protocol under moderate restricted blood flow conditions does not provide any additive effect on maximal and submaximal cycling performance. However, it seems to induce peripheral muscular adaptations, despite the lower absolute training intensity.
Hydropathy Profiles of Predicted Thyrotropin‐Releasing Hormone Precursors are Highly Conserved Despite Low Similarity of Primary Structures

Two types of cDNAs encoding thyrotropin‐releasing hormone (TRH) precursors (TRH‐A andTRH‐B) were amplified from hypothalamic mRNA of sockeye salmon by reverse transcriptase‐polymerase chain reaction (RT‐PCR). The amplification was achieved using two primers which correspond to TRH progenitor sequence (Lys/Arg‐Arg‐Gln‐His‐Pro‐Gly‐Lys/Ag‐Arg). A full length cDNA encoding TRH‐A was obtained by 5′‐ and 3′‐RACE methods. It has a length of 1324 base pairs (bp) that contains sequences of 5′ and 3′ untranslated regions and an open reading frame of 259 codons. The sockeye salmon TRH‐A deduced from the nucleotide sequence tandemly contains 8 copies of TRH progenitor sequences. Another cDNA which encodes a part of TRH‐B consists of 242 bp, and the sequence homology between TRH‐A and ‐B cDNAs is 90%. The result of Southern blot analysis of sockeye and masu salmon genomic DNAs supported the evidence that there are at least two TRH genes in the salmonid. A RT‐PCR analysis of TRH gene expression in various tissues of sockeye salmon showed that strong expression was observed only in the brain. The primary structure of the sockeye salmon TRH‐A shares low similarity to those of human, rat and Xenopus TRH precursors (35, 27 and 44%, respectively). However, their hydropathy profiles were almost the same with each other. The profile of sockeye salmon TRH‐A showed the presence of two discrete hydrophobic regions, one in the N‐terminal region which corresponds to the signal peptide and the other in the C‐terminal region. All of the repetitive TRH progenitor sequences are included in three hydrophilic regions easily recognizable. The present results thus suggest that the three‐dimensional structures of TRH precursors are highly conserved, although the primary structures of TRH precursors have diverged through the evolutionary pathway of vertebrates.
Oral Salt Supplementation During Ultradistance Exercise

ObjectiveThe objective of this study was to determine whether sodium supplementation 1) influences changes in body weight, serum sodium [Na], and plasma volume (PV), and 2) prevents hyponatremia in Ironman triathletes. SettingThe study was carried out at the South African Ironman triathlon. ParticipantsThirty-eight athletes competing in the triathlon were given salt tablets to ingest during the race. Data collected from these athletes [salt intake group (SI)] were compared with data from athletes not given salt [no salt group (NS)]. InterventionsSalt tablets were given to the SI group to provide approximately 700 mg/h of sodium. Main Outcome MeasurementsSerum sodium, hemoglobin, and hematocrit were measured at race registration and after the race. Weights were measured before and after the race. Members of SI were retrospectively matched to subjects in NS for 1) weight change and 2) pre-race [Na]. ResultsThe SI group developed a 3.3-kg weight loss (p < 0.0001) and significantly increased their [Na] (&Dgr;[Na] 1.52 mmol/L; p = 0.005). When matched for weight change during the race, SI increased their [Na] compared with NS (mean 1.52 versus 0.04 mmol/L), but this did not reach statistical significance (p = 0.08). When matched for pre-race [Na], SI had a significantly smaller percent body weight loss than NS (−4.3% versus −5.1%; p = 0.04). There was no significant difference in the increase of [Na] in both groups (1.57 versus 0.84 mmol/L). PV increased equally in both groups. None of the subjects finished the race with [Na] < 135 mmol/L. ConclusionsSodium ingestion was associated with a decrease in the extent of weight loss during the race. There was no evidence that sodium ingestion significantly influenced changes in [Na] or PV more than fluid replacement alone in the Ironman triathletes in this study. Sodium supplementation was not necessary to prevent the development of hyponatremia in these athletes who lost weight, indicating that they had only partially replaced their fluid and other losses during the Ironman triathlon.
Analysis of Road Traffic Crashes—Related Maxillofacial Injuries Severity and Concomitant Injuries in 201 Patients Seen at the UCH, Ibadan

The objective of this study was to determine the prevalence of road traffic crashes (RTC)–related maxillofacial injuries, the concomitant injuries occurring with them, and to assess the relationship between the severity of maxillofacial and concomitant injuries. This was a prospective study involving 201 victims of RTC seen at the Accident and Emergency Department of the University College Hospital, Ibadan with maxillofacial injuries during the study period. Demographic data of the patients, the types of maxillofacial injuries, and concomitant injuries sustained were recorded. Severity of maxillofacial injury was determined using the maxillofacial injury severity scale (MFISS), while the severity of concomitant injuries was based on the ISS. Correlations between types and severity of maxillofacial injury and types and severity of concomitant injury were conducted to determine the predictability of concomitant injuries based on maxillofacial injury severity. Data were processed using SPSS Statistical software (SPSS, version 20.0 for windows, IBM SPSS Inc, Chicago, IL). Maxillofacial injuries constituted 25.4% of RTC-related admission by the Accident and Emergency Department. A total of 151 (75.1%) patients who presented with concomitant injuries participated in the study. Eighty-one (53.6%) sustained injuries to more than one body region. Head injury was the commonest (99, 65.6%) concomitant injury, followed by orthopedic injury (69, 45.7%). Increasing severity of maxillofacial injury showed a positive correlation with increasing ISS. Also, positive correlation was noted with increasing severity of maxillofacial injury and presence of polytrauma (p = 0.01), traumatic brain injury (p = 0.034), and eye injuries (p = 0.034). There was a high prevalence of maxillofacial injuries in victims of RTC. There was a high incidence of concomitant injuries noted with these maxillofacial injuries. Significantly, this study showed a direct relationship between the severity of maxillofacial injury and head, ocular and polytrauma. This study further emphasizes the need for thorough examination of patients presenting with RTC-related maxillofacial injuries.
PENGARUH LEVERAGE DAN PROFITABILITAS TERHADAP NILAI PERUSAHAAN DENGAN KEBIJAKAN DIVIDEN SEBAGAI VARIABEL INTERVENING

Penelitian ini bertujuan untuk menganalisis Pengaruh Leverage dan Profitablitas terhadap Nilai Perusahaan dengan Kebijakan Dividen sebagai Variabel Intervening pada Perusahaan Manufaktur yang Terdaftar di Bursa Efek Indonesia periode 2012-2016. Sampel dalam penelitian ini berjumlah 39 perusahaan yang dipilih menggunakan metode purposive sampling. Alat analisis yang digunakan adalah analisis regresi linier berganda. Berdasarkan analisis yang telah dilakukan diperoleh hasil bahwa Leverage berpengaruh positif tidak signifikan terhadap Nilai Perusahaan. Profitabilitas berpengaruh positif signifikan terhadap Nilail Perusahaan. Leverage berpengaruh negatif signifikan terhadap Kebijakan Dividen. Profitabilitas berpengaruh positif signifikan terhadap Kebijakan Dividen. Kebijakan Dividen berpengaruh positif signifikan terhadap Nilai Perusahaan. Leverage berpengaruh terhadap Nilai Perusahaan melalui Kebijakan Dividen dan Profitabilitas berpengaruh terhadap Nilai Perusahaan melalui Kebijakan Dividen.
Substrates for muscle glycogen synthesis in recovery from intense exercise in man.

1. Intramuscular glyconeogenesis from lactate after intense exercise was examined by using the one‐legged knee extension model which enables evaluation of metabolism in a well‐defined muscle group. 2. In seven subjects measurements of leg blood flow and arterial‐venous differences of various substrates were performed in individuals after intense, exhaustive knee extensor exercise lasting 3.0 min. Muscle glycogen and lactate concentrations were determined in the quadriceps muscle immediately after exercise and three times during 1 h of recovery. 3. Muscle glycogen increased from 93.7 +/‐ 6.7 (+/‐ S.E.M.) to 108.8 +/‐ 8.1 mmol (kg wet wt)‐1 during the recovery period. Muscle lactate was 27.1 +/‐ 2.1 mmol (kg wet wt)‐1 at the end of exercise and decreased to 14.5 +/‐ 2.1, 6.7 +/‐ 1.1, and 3.0 +/‐ 0.5 mmol (kg wet wt)‐1 after 3, 10 and 60 min of recovery, respectively. 4. More than two‐thirds of the lactate that accumulated in the muscle during the intense exercise was released into the blood. It was estimated that between 13 and 27% of the lactate could have been converted to glycogen. This corresponded to a glycogen resynthesis rate from lactate of 0.17‐0.34 and 0.002 mmol glucosyl units min‐1 (kg wet wt)‐1 for the first 10 and last 50 min of recovery, respectively. 5. The O2 debt of the leg was 1.5 l of which the resynthesis of ATP, creatine phosphate (CP) and glycogen and reloading of haemoglobin (Hb) and myoglobin (Mb) only could account for one‐third. It is proposed that the elevated oxygen uptake during recovery is linked to the metabolic use of intramuscular triacylglycerol.