Miracle-dz/UniFAR-FTUs huggingface dataset:
Reuse for Modeling and Simulation

In Modeling and Simulation, as a distinct area of software engineering, there is much interest in being able to reuse software components. However, the practice of simulation development and maintenance is different from software engineering because of several factors. In this paper, a brief overview of the foundations of interoperability, and how they apply to the reuse of model based software is explored, as well as examination of current practices to include M&S software repositories. Some recommendations, based on research at the Virginia Modeling Analysis and Simulation Center (VMASC) and practice at the Raytheon Company Network Centric Services, are made.
Towards an Ideal Rowing Technique for Performance The Contributions from Biomechanics

825 1. How Much Does Rowing Technique Contribute to Rowing Performance? 826 1.1 Literature Reviewed . 827 2. Methods to Measure Rowing Biomechanics . 828 2.1 Instrumentation . 828 2.2 Ergometer versus On-Water Sculling and Sweep Rowing . 828 3. A Deterministic Biomechanical Model of Rowing Performance . 831 3.1 Boat Velocity . 831 3.2 Stroke Velocity . 833 3.2.1 Stroke Rate . 833 3.2.2 Stroke Drive Distance (Stroke Length) . 834 4. The Body Movements During the Sculling Stroke Cycle . 834 4.1 Segmental Coordination . 835 4.2 Drive to Recovery Ratio . 836 5. Forces During the Sculling Stroke Cycle . 837 5.1 External Forces . 837 5.1.1 Oar Force Profiles . 837 5.1. 2 Foot-Stretcher Force Profiles . 840 5.2 Internal Forces (Muscle Activation Patterns) . 841 6. Factors Affecting Kinematics and Kinetics of Rowing . 842 6.1 Anthropometry . 842 6.2 Equipment . 844 7. Conclusions . 845 At international standard, sculling (two oars) and rowing (one oar) are competAbstract ed on-water over 2000m. Race time is the critical measure of performance and is determined from mean skiff velocity during a race. Although a high proportion of race training is completed on-water, rowing ergometers are commonly used for performance testing, technique coaching, crew selection or for training during poor weather. Rowing biomechanics research has aimed to identify characteristics of successful sculling and sweep rowing strokes; however, biomechanical predictors of 2000m rowing performance are indistinct in the literature. If specific biomechanical parameters distinguish between ability levels and successful or unsuccessful techniques, these attributes can be considered when modifying
Aalborg Universitet Assessing ecosystem services from multifunctional trees in pastures using Bayesian belief networks

A Bayesian belief network (BBN) was developed to assess preferred combinations of trees in live fences and on pastures in silvopastoral systems. The BBN was created with information from Rivas, Nicaragua, using local farmer knowledge on tree species, trees' costs and benefits, farmers' expressed needs and aspirations, and scientific knowledge regarding tree functional traits and their contribution to ecosystem services and benefits. The model identifies combinations of trees, which provide multiple ecosystem services from pastures, improving their productivity and contribution to farmer livelihoods. We demonstrate how the identification of portfolios of multifunctional trees can satisfy a profile of desired ecosystem services prioritized by the farmer. Diagnostics using Bayesian inference starts with an identification of farmer needs and ‘works backwards’ to identify a silvopastoral system structure. We conclude that Bayesian belief networks are a promising modeling technique for multi-criteria decisions in farm adaptation processes, where interventions must be adapted to specific contexts and farmer pre-
ERCC 1 mRNA expression is associated with the clinical outcome of non-small cell lung cancer treated with platinum-based chemotherapy

We conducted a prospective study to analyze the expression of the excision repair cross-complementing group 1 (ERCC1) and ribonucleotide reductase subunit M1 (RRM1) genes in 297 Chinese patients with advanced non-small cell lung cancer (NSCLC). The goal of this study was to evaluate these genes as potential biomarkers for prediction of tumor response and clinical outcome. Patients with unresectable, locally advanced or metastatic NSCLC were enrolled between September 2007 and September 2009, and they were followed up until September 2012. A fluorescence-based real-time detection method was used to quantify relative levels of ERCC1 and RRM1 cDNA. Relative amounts of ERCC1 and RRM1 cDNA were calculated by comparing to actin. By
Chvátal Rank in Binary Polynomial Optimization

Recently, several classes of cutting planes have been introduced for binary polynomial optimization. In this paper, we present the first results connecting the combinatorial structure of these inequalities with their Chvátal rank. We determine the Chvátal rank of all known cutting planes and show that almost all of them have Chvátal rank 1. We observe that these inequalities have an associated hypergraph that is β-acyclic. Our second goal is to derive deeper cutting planes; to do so, we consider hypergraphs that admit β-cycles. We introduce a novel class of valid inequalities arising from odd β-cycles, that generally have Chvátal rank 2. These inequalities allow us to obtain the first characterization of the multilinear polytope for hypergraphs that contain β-cycles. Namely, we show that the multilinear polytope for cycle hypergraphs is given by the standard linearization inequalities, flower inequalities, and odd β-cycle inequalities. We also prove that odd β-cycle inequalities can be separated in linear time when the hypergraph is a cycle hypergraph. This shows that instances represented by cycle hypergraphs can be solved in polynomial time. Last, to test the strength of odd β-cycle inequalities, we perform numerical experiments that imply that they close a significant percentage of the integrality gap.
The value of tumor angiogenesis activity for stratification of HCC patients

The study aimed to evaluate whether the identification of angiogenesis factors improves the system of clinical classification and allows for choice of more appropriate candidates for surgery. The cohort study covered 180 patients. Ninety two of them underwent radical treatment: 48 liver resection, 44 liver transplantation. Eighty eight patients were selected for palliative treatment. Endothelial progenitor cells in the blood were assessed with a flow cytometer, serum VEGF concentration was measured by ELISA. HCC samples were examined for morphologic characteristics and stained for VEGF and VEGFR concentration within tumor tissue. Patients were followed up to 3 years after the surgery. With the use of the multivariate analysis model we identified the angiogenesis factors that are significant for the appropriate stratification of candidate for the radical treatment (P-value < 0.05). Patients considered as eligible for the radical surgical treatment had lower levels of angiogenesis factors than those chosen for the palliative care (P < 0.001). The optimal cutoff identified for the rate of circulating EPCs, serum VEGF level, and tumor VEGF concentration was 47.08%, 327.2 pg/mL and 83.16 morphometric units, respectively. In 30% of patients undergoing surgery HCC recurred within 3 years. The preoperative level of angiogenesis factors exceeded the value of the cutoff in all of them (P < 0.001). The multivariate analysis showed an increased EPCs level as the strongest independent factor indicating tumor unfavorable biology and the possibility of relapse after surgery (Odds Ratio = 15.5, P < 0.001). We conclude that the assessment of angiogenesis factors improves the clinical evaluation and allows for more accurate stratification of patients for surgery.
FIW – Working Paper What if all countries were actually in the same boat ? A comparison of countries ’ vulnerability based on Markov Switching Models

This article aims at assessing the main characteristics of the business cycle of 80 developed and developing countries. By comparing the possibility for these economies to enter or to exit a recession and the associated consequences, it aims at complementing existing literature with regard to scale and/or frequency of the study. Following the usual definition of a recession, an algorithmic classification tends to show that, surprisingly, developed and developing countries face similar probabilities to enter or to exit a recession, respectively around 5% and 18%. This aspect contradicts existing literature, which often advocates a greater volatility of developing countries’ business cycle with more frequent recessions. However emerging markets and economies face output per capita losses around twice as important as advanced ones when they undergo a recession. These observations are then tested using a non-linear parametric Markov-Switching Model. If the statistical validity of this method is bound by data availability, it echoes in a really good manner the pattern derived using a non-parametric approach. Estimating the model on the cyclical component of the series, derived using an HP filter, fits the best previous remarks. It also replicates other major characteristics. Indeed while developed countries form a rather homogeneous group, developing countries demonstrate greater heterogeneity. Latin American countries appear as the most vulnerable ones whereas Asian countries perform better than all other groups. Keyword: Business Cycles, Economic Growth, Vulnerability, Markov Switching Models. JEL Codes: F43, C32, O57 ⇤I thank Professor Daniel Cohen for the numerous useful advices, Mathieu Gex and colleagues at the Banque de France for their constructive remarks, and Mathilde Viennot and Paul Beaumont for insightful discussions. †brendan.vannier@gmail.com
Haplotypic analyses of the aldosterone synthase gene CYP 11 B 2 associated with stage-2 hypertension in northern

The objective of this study was to investigate the association of polymorphisms in the aldosterone synthase gene CYP11B2 ( 344T/C, Lys173/Arg, and an intronic conversion [IC]) with stage-2 hypertension in northern Han Chinese. A total of 503 hypertensives and their age-, gender-, and area-matched controls were included in this study. The female hypertensives had significantly higher frequencies of the 344T, 173Lys, and IC-conversion alleles (p1⁄4 0.002, 0.002, and 0.014, respectively). The estimated frequency of haplotype composed of the 344T, 173Lys, and IC-conversion alleles (haplotype 4) was significantly higher in the female hypertensives compared with their controls (p1⁄4 0.007). Using a multivariate score test, we found that haplotype 4 remained associated with female hypertension after the adjustment for covariates (p1⁄4 0.003), while the haplotype 3 of T-ArgWT showed a protective effect both in the males and in the females (p1⁄4 0.03 and 0.006, respectively). The odds ratio for haplotype phase of 4–4 was 2.60 (95% CI, 1.21–5.58) and for 3–3, 0.20 (95%CI, 0.03–0.77). These results indicate that the Lys173 and the IC-conversion allele of the CYP11B2 gene confer an increased risk for stage-2 hypertension in northern Han Chinese women.
Aalborg Universitet Ensemble prediction model with expert selection for electricity price forecasting

Forecasting of electricity prices is important in deregulated electricity markets for all of the stakeholders: energy wholesalers, traders, retailers and consumers. Electricity price forecasting is an inherently difficult problem due to its special characteristic of dynamicity and non-stationarity. In this paper, we present a robust price forecasting mechanism that shows resilience towards the aggregate demand response effect and provides highly accurate forecasted electricity prices to the stakeholders in a dynamic environment. We employ an ensemble prediction model in which a group of different algorithms participates in forecasting 1-h ahead the price for each hour of a day. We propose two different strategies, namely, the Fixed Weight Method (FWM) and the Varying Weight Method (VWM), for selecting each hour’s expert algorithm from the set of participating algorithms. In addition, we utilize a carefully engineered set of features selected from a pool of features extracted from the past electricity price data, weather data and calendar data. The proposed ensemble model offers better results than the Autoregressive Integrated Moving Average (ARIMA) method, the Pattern Sequence-based Forecasting (PSF) method and our previous work using Artificial Neural Networks (ANN) alone on the datasets for New York, Australian and Spanish electricity markets.
Implanted Intraocular Devices for the Treatment of Glaucoma

Description: Glaucoma is a group of eye diseases traditionally characterized by elevated intraocular pressure (IOP). However, glaucoma is more accurately described as disease affecting the optic nerve rather than a disease of high pressure. It is the second leading cause of blindness and can damage vision so gradually one may not notice any loss of vision until the disease is at an advanced stage. Standard therapy involves either topical medications or surgical intervention. The most commonly performed surgeries are laser trabeculoplasties, tube shunts such as the Baerveldt or Ahmed valve, micro-shunts, or iridectomies, depending upon the severity and type of glaucoma.
Histological features of Vomer nasal organ in Indigenous Gazelle (Gazella subgutturosa)

The present investigation was carried out to study the histological features of vomer nasal organ in Indigenous Gazelle. Six adult Gazelle were used. The results indicate that, the Vomer nasal organ was symmetrical tubular organ included two parts: Conducting and olfactory parts. Olfactory part involved vomer nasal duct. The conducting part involved the incisive duct and incisive papilla which lined by stratified squamous epithelium, the incisive duct measured (623.8±12.1µm) in diameter and lined by ciliated pseudo stratified columnar epithelium. The vomer nasal duct has significant widest diameter (1040±50.9µm) and oval- circular lumen with two walls; medial wall was lined with neuro-epithelium which has significant epithelial height (83.0±2.4µm), lateral wall has lined with respiratory epithelium of height (43.4±3.6µm). The lamina propria- submucosa beneath medial wall was loose connective tissue contained many of wide veins and axons. The lamina propria- submucosa beneath incisive duct and lateral wall possessed compound tubuloalveolar mucous glands.
Title Nonlocal In-Loop Filter : The Way Toward Next-Generation Video Coding ?

In-loop filtering has emerged as an essential coding tool since H.264/AVC due to the delicate design in reducing different kinds of compression artifacts. However, existing in-loop filters only rely on image local correlations, where the nonlocal similarities have been largely ignored. In this paper, we journey through the design philosophy of in-loop filters and discuss our vision for the future of in-loop filter research by exploring the potential of non-local similarities. Specifically, the group-based sparse representation, which jointly exploits image local and nonlocal self-similarities, lays a novel and meaningful groundwork to the in-loop filter design. Hardand soft-thresholding filtering operations are further applied to derive the sparse parameters that are appropriate for the compression artifacts reduction. Experimental results show that such in-loop filter design can significantly improve the compression performance on top of the High Efficiency Video Coding (HEVC) standard, leading us a new direction to improve the compression efficiency in the future.
Burnout and job engagement in UK cancer care staff : how do they relate to job stress and satisfaction and turnover intentions

Background: Health care professionals are at risk of developing burnout due to the inherently stressful nature of their work. Burnout has been found to compromise the wellbeing of health care professionals and their ability to provide optimal patient care. Job engagement is proposed to be the antipode of burnout and is concerned with occupational well-being. It is hoped that through a better understanding of factors related to job engagement and burnout, occupational well-being of health care professionals and their ability to care for patients can be improved. Systematic review: A systematic review of the literature on burnout and job engagement in physicians and nurses since 2002 identified seven studies. Findings suggest that burnout and job engagement are independent constructs, albeit negatively related. These findings contribute to the current knowledge about the relationships between burnout and engagement dimensions and provide a framework for interventions aimed at increasing occupational well-being among front line medical professionals. Aims: A study was conducted to assess levels of job engagement and burnout and their relationship with turnover intentions and job satisfaction and stress in the entire workforce of a Cancer Centre in the United Kingdom. Participants and procedure: 150 cancer care workers completed a cross-sectional questionnaire entailing the Maslach Burnout Inventory, the Engagement Indicator, measures of job satisfaction, stress, turnover intentions and demographics. Results: Mean scores of emotional exhaustion did not differ from normative data, while lower levels of depersonalisation and lack of accomplishment were found. Furthermore, engagement scores were significantly higher than in the normative sample and the majority reported high levels of job satisfaction and indicated no turnover intentions. Path analysis provided preliminary support for an exploratory model indicating that engagement mediates the relationship between job stress, burnout and job satisfaction and turnover intentions. Implications: It is important that, despite increasing pressure to reduce costs, service planning is mindful of the continuous and long-term process required to maintain and facilitate engagement and job satisfaction, which appear important to the long term retention of staff. Conclusions: Work overload and a perception of being poorly managed and resourced appear to be risk factors for burnout. However, engaged employees with high levels of personal accomplishment may experience job satisfaction and desire to stay in their jobs despite high levels of occupational stress. Further research is required to identify factors predictive of personal accomplishment and job engagement in oncology services. Abstract
The Effects of Safety Leadership on Safety Performance in Malaysia

In the new global economy, workplace safety has assumed central importance among companies across the world: this has been evident in Malaysia, especially the manufacturing sector. The worrying lack of workplace can be discerned from the increasing number of workplace accidents in manufacturing companies as reported by the Department of Occupational Safety and Health (DOSH), Malaysia. In recent years, researchers have shown an interest in studying the role of safety leadership in reducing workplace accidents. It is found that safety leadership plays a significant role in ensuring a safe and sound workplace. Against this background, this paper attempts to conceptualize safety leadership from the perspective of Malaysia’s manufacturing sector. It is hypothesized that the higher level of safety leadership will reduce the occurrence of workplace accidents. A questionnaire from Wu et al. (2008) will be adopted to explore and explain the conceptualization of safety leadership. It is expected that safety leadership practiced in Malaysia’s manufacturing sector is conceptualized in a manner similar to the perspective of western researchers. Article Information: This paper was first presented at the First International Conference on Management and Social Sciences (ICMSS 2019), organised by the School of Human Resource Development and Psychology, Universiti Teknologi Malaysia, Johor Bahru, Johor, Malaysia, on 27 April 2019. Published after peer review: November 2019.
1 High Density SNP and DArT-based Genetic Linkage Maps of Two Closely Related Oil Palm Populations 1

21 Oil palm (Elaeis guineensis Jacq.) is an outbreeding perennial tree crop with long breeding cycles, typically 12 22 years. Molecular marker technologies can greatly improve the breeding efficiency of oil palm. This study reports 23 the first use of the DArTseq platform to genotype two closely related self-pollinated oil palm populations, namely 24 AA0768 and AA0769 with 48 and 58 progeny respectively. Genetic maps were constructed using the DArT and 25 SNP markers generated, in combination with anchor SSR markers. Both maps consisted of 16 major independent 26 linkage groups (2n = 2x = 32) with 1399 and 1466 mapped markers for the AA0768 and AA0769 populations, 27 respectively, including the morphological trait “Shell-thickness” (Sh). The map lengths were 1873.7, and 1720.6 28 cM with an average marker density of 1.34 and 1.17 cM, respectively. The integrated map was 1803.1 cM long 29 with 2066 mapped markers and average marker density of 0.87 cM. A total of 82% of the DArTseq marker 30 sequence tags identified a single site in the published genome sequence, suggesting preferential targeting of gene31 rich regions by DArTseq markers. Map integration of higher density focused around the Sh region identified 32 closely linked markers to the Sh, with D.15322 marker 0.24 cM away from the morphological trait and 5071 bp 33 from the transcriptional start of the published SHELL gene. Identification of the Sh marker demonstrates the 34 robustness of using the DArTseq platform to generate high density genetic maps of oil palm with good genome 35 coverage. Both genetic maps and integrated map will be useful for quantitative trait loci analysis of important 36 yield traits as well as potentially assisting the anchoring of genetic maps to genomic sequences. 37
Impact of Long Term Metformin Therapy on Hepcidin and Iron Status in Type II Diabetic Patients

Background /Aims: Diabetes and its complications are considered as a major public health problem in the world and the prevention of these complications has become a public health priority. The recent discovery of hepcidin, the central regulatory molecule of systemic iron homeostasis, changed the view of iron metabolism, which is long known to be linked with insulin resistant status in type 2 diabetes mellitus. Thus, the aim of the current study was to elucidate the impact of metformin administration for long time on iron regulator hepcidin and iron metabolic parameters (Hb, ferritin, TIBC) in Type 2 diabetic patients. Subjects Methods: This study included 45 subjects of both sexes, the age between 3560 years. Thirty cases with type 2 diabetes who divided into two groups: L-group, treated with metformin for less than 5 years and A-group, treated with metformin for more than 5 years. These groups were compared with the healthy sex and age matched control group (n=15). Fasting blood glucose (FBG), serum insulin, blood hemoglobin (Hb), serum hepcidin, ferritin, Iron and total iron binding capacity (TIBC) have been carried out. Results: The present results recorded highly significant increase in serum hepcidin level in A-group and significant increase in L-group versus the control group. Serum insulin group as well as serum insulin, ferritin and TIBC levels showed highly significant increase in A-group with insignificant increase in L-grouprelative to the control group. Significant depletion in blood Hb as well as in serum iron levels were demonstrated in both A-and L-group with respect to the controlgroup. Hepcidin showed a significant positive correlation with FBG, insulin and ferritin in both diabetic groups (A-and L-group), while it showed a negative correlation with HB and serum iron. Conclusion: The current study provided an evidence for that metformin administration in Type 2 diabetic patients for long time (more than 5 years) caused anima, heperferritinemia, iron deficiency as well as marked increase in serum hepcidin indicating iron overload in liver of these patients.