Miracle-dz/UniFAR-FTUs huggingface dataset:
The Effect of Psychological Suzhi on Problem Behaviors in Chinese Adolescents: The Mediating Role of Subjective Social Status and Self-esteem

In this study, we examined subjective social status (SSS) and self-esteem as potential mediators between the association of psychological suzhi and problem behaviors in a sample of 1271 Chinese adolescents (44.5% male, grades 7–12). The results showed that SSS and self-esteem were fully mediating the relationship between psychological suzhi and problem behaviors. Moreover, the indirect effect was stronger via self-esteem than via SSS. These findings perhaps provide insight into the preliminary effect that SSS and self-esteem underlie psychological suzhi’s effect on adolescents’ problem behaviors, and also are important in helping school-teachers and administrators to develop a better understanding of problem behaviors in their schools as a pre-requisite to the development of more effective behaviors management practices from the perspective of psychological suzhi. Implications and limitations in the present study have also been discussed.
Sense of Community in a Context of Community Violence

The following study analyzes the concept of sense of community of a group of people living in a shanty town in a district in the eastern outskirts of Lima, characterized by processes of community violence. With this in mind, a mixed methodology and a concurrent design were chosen, applying the Scale of Sense of Community, SCI-2, a question to measure the perceived level of danger through a Likert scale, and five individual interviews with the population. The results show that the higher the level of danger perceived in the zone, the lower the sense of community is. Likewise, in this group of people their sense of community is based above all on an emotional shared connection and on a strong feeling of membership. On the contrary, the difficulty to satisfy their collective needs through organization and the weak relationship that exists between the population and its leaders, decrease and deteriorate the sense of community in this group.
Ectodomain shedding of CD99 within highly conserved regions is mediated by the metalloprotease meprin β and promotes transendothelial cell migration

The adhesion molecule CD99 is essential for the transendothelial migration of leukocytes. In this study, we used biochemical and cellular assays to show that CD99 undergoes ectodomain shedding by the metalloprotease meprin β and subsequent intramembrane proteolysis by γ‐secretase. The cleavage site in CD99 was identified by mass spectrometry within an acidic region highly conserved through different vertebrate species. This finding fits perfectly to the unique cleavage specificity of meprin β with a strong preference for aspartate residues and suggests coevolution of protease and substrate. We hypothesized that limited CD99 cleavage by meprin β would alter cellular transendothelial migration (TEM) behavior in tissue remodeling processes, such as inflammation and cancer. Indeed, meprin β induced cell migration of Lewis lung carcinoma cells in an in vitro TEM assay. Accordingly, deficiency of meprin β in Mep1b−/− mice resulted in significantly increased CD99 protein levels in the lung. Therefore, meprin β could serve as a therapeutic target, given that in a proof‐of‐concept approach we showed accumulation of CD99 protein in lungs of meprin β inhibitor‐treated mice. —Bedau, T. , Peters, F. , Prox, J., Arnold, P., Schmidt, F. , Finkernagel, M. , Köllmann, S. , Wichert, R. , Otte, A. , Ohler, A. , Stirnberg, M. , Lucius, R. , Koudelka, T. , Tholey, A. , Biasin, V. , Pietrzik, C. U. , Kwapiszewska, G. , Becker‐Pauly, C. Ectodomain shedding of CD99 within highly conserved regions is mediated by the metalloprotease meprin β and promotes transendothelial cell migration. FASEB J. 31, 1226–1237 (2017). www.fasebj. org
Coil design for 100 KHz and 6.78 MHz WPT system :Litz and solid wires and winding methods

Coil design is one of the critical part to get high power transfer efficiency for wireless power transfer (WPT) system. There exists coil figure of merit (FOM), which is used to evaluate coil design in the aspect of WPT system efficiency. WPT coil FOM is function of coil quality factor (Q-factor) and coupling coefficient, k and higher Q and k guarantees higher coil-to-coil efficiency. Coil DC loss, skin effect, proximity effect, and displacement current between turns are key factors to determine Q-factor and its effects changes depending on wire-type, winding method, and target frequency. In this paper, we focus on transmitter coil design to maximize Q-factor in both 100 MHz and 6.78 MHz. Coil Q-factor equations are provided to explain and analyze the physics and measurement was done for the validation of the equation. Finally optimal coil winding methods are proposed to maximize coil Q-factor
RecA Protein from the Extremely Radioresistant Bacterium Deinococcus radiodurans: Expression, Purification, and Characterization

ABSTRACT The RecA protein of Deinococcus radiodurans (RecADr) is essential for the extreme radiation resistance of this organism. The RecADr protein has been cloned and expressed in Escherichia coli and purified from this host. In some respects, the RecADr protein and the E. coli RecA (RecAEc) proteins are close functional homologues. RecADr forms filaments on single-stranded DNA (ssDNA) that are similar to those formed by the RecAEc. The RecADr protein hydrolyzes ATP and dATP and promotes DNA strand exchange reactions. DNA strand exchange is greatly facilitated by the E. coli SSB protein. As is the case with the E. coli RecA protein, the use of dATP as a cofactor permits more facile displacement of bound SSB protein from ssDNA. However, there are important differences as well. The RecADr protein promotes ATP- and dATP-dependent reactions with distinctly different pH profiles. Although dATP is hydrolyzed at approximately the same rate at pHs 7.5 and 8.1, dATP supports an efficient DNA strand exchange only at pH 8.1. At both pHs, ATP supports efficient DNA strand exchange through heterologous insertions but dATP does not. Thus, dATP enhances the binding of RecADr protein to ssDNA and the displacement of ssDNA binding protein, but the hydrolysis of dATP is poorly coupled to DNA strand exchange. The RecADr protein thus may offer new insights into the role of ATP hydrolysis in the DNA strand exchange reactions promoted by the bacterial RecA proteins. In addition, the RecADr protein binds much better to duplex DNA than the RecAEc protein, binding preferentially to double-stranded DNA (dsDNA) even when ssDNA is present in the solutions. This may be of significance in the pathways for dsDNA break repair in Deinococcus.
Increased prospective memory interference in normal and pathological aging: different roles of motor and verbal processing speed

ABSTRACT This is a study on prospective memory (PM) and the PM interference effect in normal and pathological aging. One hundred and seven subjects, including 41 healthy young adults, 40 non-demented older adults and 26 patients with mild Alzheimer's disease (AD) participated in this study using a laboratory event-based PM task. PM task performance was comparable between the non-demented older and young adults, but impaired in the AD patients. The PM interference effect increased progressively from the healthy young adults, the non-demented older adults, to the AD patients. Path analysis revealed that the possible mechanism mediating the increased PM interference was the slow motor processing speed in normal aging, while it was the slow verbal speed in pathological aging. It is suggested that different neuropsychological mechanisms may underpin the affected performance of PM task in normal and pathological aging.
Perinatal stroke – risk factors and management

Stroke is an uncommon but increasingly recognised cause of mortality and long‐term neurological morbidity in children. A significant number of these events appear to be caused by thromboembolic disease and, as with other childhood thrombotic problems, the incidence of central nervous system events appears highest during the neonatal period. In contrast to peripheral arterial and venous thrombotic problems, it is likely that a proportion of cerebral thromboembolic events occur either in utero or perinatally and reflect different risk factors from those occurring in older infants and children. The pathophysiology of perinatal stroke is complex and in many cases is likely to be multifactorial. It is now recognised that risk factors may relate to both maternal and placental problems as well as fetal and neonatal disorders. Large prospective studies of perinatal stroke are currently lacking and efforts to define the relative contribution from each of these areas are at an early stage. The complex nature of these disorders requires collaboration between a number of different disciplines including obstetrics, fetal medicine, pathology, neonatology and neurology. Of particular interest to haematologists is the possible impact of prothrombotic abnormalities in the pathophysiology of these events and also the potential for the use of antithrombotic agents in both management and prevention.
The Relationship Between Different Pain Assessments in Dementia

Persons with dementia have difficulty communicating, which has led to the underdetection and undertreatment of pain in this population. In this paper, we compare pain assessments using 3 different measurement types: self-report, informant rating, and observational assessments. Participants were 153 nursing home residents from 4 nursing homes. Four different self-report assessments were compared with 3 observational scales and 2 informant-based assessments, which included 3 summary rating scales. Only 60% of participants were able to complete atleast 1 of the self-report assessments. The strongest correlations between assessments were found among instruments of the same type, that is, among the different self-report measures, among the different observational measures, between the 2 informant rating questionnaires, and among the 3 informant rating summary questions. Our results show that the different formats of pain assessments resulted in somewhat overlapping results, yet the differences were much larger than those obtained from different assessments within the same format type. The results reraise the questions of what pain is in this population, and whether the new assessments aimed to uncover such pain have targeted the correct construct. Results suggest that a multimethod type assessment may be needed to effectively manage pain.
An Efficient Supply Modulator for Linear Wideband RF Power Amplifiers

An Efficient Supply Modulator for Linear Wideband RF Power Amplifiers (August 2011) Richard Turkson Chair of Advisory Committee: Jose Silva-Martinez Radio Frequency (RF) Power Amplifiers are responsible for a considerable amount of the power consumption in the entire transmitter-receiver (transceiver) of modern communication systems. The stringent linearity requirements of multi-standard transceivers to minimize cross-talking effects makes Linear Power Amplifiers, particularly class A, the preferred choice in broadband transceivers. This linearity requirement coupled with the fact that the Power Amplifier operates at low transmit power during most of its operation makes the efficiency of the entire transceiver poor. The limited transceiver efficiency leads to a reduction in the battery life of battery operated portable devices like mobile phones; hence drastically limiting talk time. To alleviate this issue, several research groups propose solutions to improve PA power efficiency. However, these solutions usually have a low efficiency at low power and are mostly limited to narrow bandwidth applications. In this thesis, the efficiency of a class A Power amplifier in wideband wireless standards like WiMax is improved by dynamically controlling the bias current and supply voltage of the PA. An efficient supply modulator based on a switching regulator architecture is proposed for controlling the supply voltage. The switching regulator is found to be slew-limited by the bulky inductor and capacitor used to regulate the supply voltage. The proposed solution alleviates the slew rate limitation by adding a bang-bang controlled current source. The proposed supply modulator has an average power efficiency of 81.6 percent and is suitable for wireless standards with bandwidths up to 20MHz compared to the relatively lower efficiencies and bandwidths of state of the art modulators. A class-A PA is shown to promise an average power efficiency of 21.3 percent when the bias current is controlled dynamically and the supply voltage is varied using the proposed supply modulator. This is a significant improvement over the poor average efficiency of 1.06 percent for a fixed bias conventional linear class A PA. The project has been simulated using the TSMC 0.18 micrometer technology.
Regulating emotion expression and regulating emotion experience: divergent associations with dimensions of attachment among older women

Adult attachment research does not systematically distinguish between experiential and expressive forms of regulation. Drawing insights from developmental-functionalism – a lifespan theory of emotion and emotion regulation – the current report examined the relations among attachment, trait emotion, and expressive emotion regulation in a large (N = 1204) sample of older women. Although both preoccupation and fearful-avoidance predicted more anxiety and anger, preoccupation predicted greater fear withdrawal and less fear expression, while fearful-avoidance predicted greater fear expression and greater anger withdrawal; attachment security predicted less fear withdrawal and less anger expression. Importantly, results regarding expressive regulation held even when controlling for trait levels of the underlying emotion. Results are interpreted within the context of models of attachment and lifespan socioemotional functioning. It is suggested that attachment research may benefit from considering the distinct functions of experienced versus expressed emotion in developmentally diverse contexts. Limitations are discussed and directions for future research are given.
Efficacy of Phoma macrostoma , a Bioherbicide , for Control of Dandelion ( Taraxacum officinale ) Following Simulated Rainfall Conditions

This study evaluated the efficacy of the bioherbicide P. macrostoma under simulated rainfall conditions to determine whether bioactivity was retained in the soil and whether bioherbicidal metabolites would be soluble in water possibly posing a risk to off-site hosts. Various application rates of the bioherbicide were leached with water equivalent to 25-250 mm of precipitation and tested for efficacy before and after leaching using a dandelion bioassay. The percolated water was collected in six fractions (F1-F6) and similarly tested for bioactivity using a dandelion bioassay. Relative concentrations of macrocidin A, the main bioherbicidal metabolite, were estimated by HPLC. DNAspecific primers were used to detect the presence of the fungus in soil. Of three soil types treated with the bioherbicide, all lost the ability to control dandelion after being leached. Clay, as compared to sandy loam and greenhouse soil mix, retained the most bioherbicidal activity. The bioherbicidal metabolite was soluble in water with up to 80% macrocidin A being released in 75 mm of water and bioactivity occurring in fractions F1-F3, with much less or no activity in fractions F4-F6. The impact of water on the distribution of the living component of the bioherbicide was not clearly determined. The study shows that water releases macrocidins from the bioherbicide allowing the compound to be taken up by the roots of the plant, subsequently resulting in plant death. When soils are at field capacity or drier, this amount of rainfall is of little concern as the bioactivity is localized. However under saturated soils, macrocidins may be released in the soil water and if not taken up by the plants, run-off water may pose a risk to off-site hosts. Factors that mitigate the risks associated with off-site movement are discussed. _____________________________________________________________________________________________________________
Socioeconomic deprivation, mortality and health of within-city migrants: a population cohort study

Background Evidence linking selective migration (the situation where people in good health move from deprived to affluent areas, whilst people in poor health move in the opposite direction) within local areas to mortality is inconclusive. Methods Mortality in within-city migrants was examined using a Sheffield population cohort, adjusted for moves to care homes. The cohort comprised 310 894 people aged 25+ years in 2001 followed up for 9.18 years, with 42 252 (13.6%) deaths. Information on pre-existing medical conditions, socioeconomic indicators and smoking was available from a sample survey. Results Relative risks (95% CI) of mortality in migrants from deprived to affluent areas were lower compared with people remaining in deprived areas; 0.53 (0.42 to 0.65), 0.70 (0.61 to 0.80), 0.76 (0.68 to 0.86), 0.93 (0.88 to 1.00) and 0.98 (0.93 to 1.03) in the 25–44, 45–64, 65–74, 75–84 and 85+ year age bands, respectively. They also had lower prevalence ORs (95% CI) for bronchitis (0.59 (0.39 to 0.89)), asthma (0.70 (0.53 to 0.93)), depression (0.59 (0.38 to 0.94)), and were less likely to receive benefits (0.60 (0.47 to 0.76)) and less likely to smoke (0.66 (0.51 to 0.85)). Conversely, mortality relative risks in migrants from affluent to deprived areas were higher compared with people remaining in affluent areas; 1.71 (1.37 to 2.12), 1.59 (1.40 to 1.82), 1.44 (1.26 to 1.63), 1.18 (1.10 to 1.27) and 1.04 (1.00 to 1.09) in the corresponding age groups. They also had higher prevalence odds ratios for long-term illness (2.37 (1.71 to 3.29)), asthma (1.71 (1.25 to 2.35)), diabetes (3.03 (1.70 to 5.41)), depression (2.71 (1.74 to 4.21)), were more likely to receive benefits (2.25 (1.65 to 3.07)) and more likely to smoke (1.51 (1.12 to 2.05)). Conclusions People moving from deprived to affluent areas had lower mortality and better health, and vice versa, especially in the younger age groups. This study provides strong evidence linking selective migration within local areas to mortality.
Transformational Leadership in the Local Police in Spain: a Leader-Follower Distance Approach

Abstract Based on the transformational leadership theory (Bass, 1985), the aim of the present study was to analyze the differences in leadership styles according to the various leading ranks and the organizational follower-leader distance reported by a representative sample of 975 local police members (828 male and 147 female) from Valencian Community (Spain). Results showed differences by rank (p < .01), and by rank distance (p < .05). The general intendents showed the most optimal profile of leadership in all the variables examined (transformational-leadership behaviors, transactional-leadership behaviors, laissez-faire behaviors, satisfaction with the leader, extra effort by follower, and perceived leadership effectiveness). By contrast, the least optimal profiles were presented by intendents. Finally, the maximum distance (five ranks) generally yielded the most optimal profiles, whereas the 3-rank distance generally produced the least optimal profiles for all variables examined. Outcomes and practical implications for the workforce dimensioning are also discussed.
Recent developments in methods for identifying reaction coordinates

In the study of rare events in complex systems with many degrees of freedom, a key element is to identify the reaction coordinates of a given process. Over recent years, a number of methods and protocols have been developed to extract the reaction coordinates based on limited information from molecular dynamics simulations. In this review, we provide a brief survey over a number of major methods developed in the past decade, some of which are discussed in greater detail, to provide an overview of the problems that are partially solved and challenges that still remain. A particular emphasis has been placed on methods for identifying reaction coordinates that are related to the committor.
A case of neonatal linear IgA bullous dermatosis with severe eye involvement.

© 2015 The Authors. doi: 10.2340/00015555-2074 Journal Compilation © 2015 Acta Dermato-Venereologica. ISSN 0001-5555 Linear IgA bullous dermatosis (LABD) of childhood is a chronic autoimmune blistering disease characterised by linear deposition of IgA at the cutaneous basement membrane zone (BMZ) (1–4). Although LABD is rare, it represents the most common autoimmune blistering disorder of childhood (1–3, 5, 6). The childhood variant of LABD has a mean age of onset between 4 and 5 years (1, 3, 4). The clinical presentation is characterised by a sudden eruption of clear vesicles and blisters on normal or erythematous skin, affecting at first the perineum and perioral area. Typically, new blisters develop around resolving lesions resulting in an annular or “rosette-like” configuration. Mucosal involvement is common and manifests with conjunctivitis, oral and nasal erosions (2, 3, 4, 6). Ocular lesions can be severe leading to symblepharon, trichiasis, shrinkage of fornices and, rarely, corneal opacities (6). The disease has a chronic relapsing course and in the majority of cases resolves before puberty (1, 5). A few neonatal cases of LABD have been described (7–13). Mucosal involvement was predominant in these patients. We present a rare case of LABD in a neonate with severe ocular manifestations.
Methods for the detection and characterisation of noroviruses associated with outbreaks of gastroenteritis: Outbreaks occurring in the north‐west of England during two norovirus seasons

This article describes the methods used to investigate 407 outbreaks of acute non‐bacterial gastroenteritis occurring in the North‐West of England between January 2000 and July 2001 and suspected to be caused by noroviruses (NV) [Mayo (2002) Arch Virol 147:1655–1663]. These included 319 outbreaks in hospitals and nursing homes and 88 other settings. Eight hundred and seventy‐one faecal samples from 407 outbreaks were tested using electron microscopy (EM), an enzyme‐linked immunosorbent assay (ELISA) specific for Grimsby virus (GRV) capsid antigen and/or by reverse transcriptase‐polymerase chain reaction (RT‐PCR) for NV, allowing the utility of each assay for routine diagnosis to be assessed. Preliminary genomic characterisation of detected strains was performed using the heteroduplex mobility assay (HMA) and DNA sequencing. The results demonstrate the continuing predominance of GII‐4 GRV strain of NV as a cause of outbreaks, particularly in hospital and nursing home settings. Overall, NV were detected in 223/407 (55%) of outbreaks tested. However, a wide range of apparently diverse strains was identified, including several not previously reported. Genomic characterisation revealed clusters of linked outbreaks not recognised previously. J. Med. Virol. 73:280–288, 2004. © 2004 Wiley‐Liss, Inc.
Fracture healing in the rabbit fibula when subjected to various capacitively coupled electrical fields

The effect of capacitively coupled electrical stimulation on the healing of midshaft transverse osteotomies of the rabbit fibula is assessed roentgenographically, mechanically, and histologically. The results show that a dose‐response curve for capacitive coupling and fracture healing exists and that a 220 mV, 250 μA, 60 kHz applied electrical signal (0.33 V/cm internal electric field) is the most effective signal for fracture stimulation in this model.