Miracle-dz/UniFAR-FTUs huggingface dataset:
Fascial structures and autonomic nerves in the female pelvis: A study using macroscopic slices and their corresponding histology

We investigated the topographical anatomy of the pelvic fasciae and autonomic nerves using macroscopic slices of five decalcified female pelves. The lateral aspect of the supravaginal cervix uteri and superior-most vagina issued abundant thick fiber bundles. These visceral fibrous tissues extended dorsolaterally, joined another fibrous tissue from the rectum (the actual lateral ligament of the rectum) and attached to the parietal fibrous tissues at and around the sciatic foramina (i.e. the sacrospinous ligament, thick fasciae of the coccygeus and piriformis and dorsal end of the covering fascia of the levator ani). The inferior or ventral vagina also issued thick fiber bundles communicating with the levator ani fascia. This connection between the vagina and levator fascia, when stretched, seemed to provide a macroscopic morphology called the arcus tendineus fasciae pelvis. The overall morphology of the visceroparietal fascial bridge exhibited a bilateral wing-like shape. The fascial bridge complex was adjacent but dorso-inferior to the internal iliac vascular sheath and located slightly ventral to the pelvic splanchnic nerve. However, the pelvic plexus and its peripheral branches were embedded in the fascial complex. The hypogastric nerve ran along and beneath the uterosacral peritoneal fold, which did not contain thick fibrous tissue. During surgery, in combination with the superficially located vascular sheath, the morphology of the visceroparietal fascial bridge and associated nerves seemed to be artificially changed and developed into the so-called cardinal, uterosacral, uterovesical and/or rectal lateral ligaments. The classical and original concepts of these pelvic fascial structures may need to be altered to adjust to these surgical observations.
The natural history of epilepsy: an epidemiological view

Better information of the natural history of epilepsy has important implications for understanding the underlying neurobiology, evaluating treatment strategies, and planning healthcare resources. The traditional pessimistic view has been dispelled by results from modern community based prospective studies, showing that over 60% of newly diagnosed patients will enter remission upon treatment. Recent outcome studies suggest that medical intractability may be predicted after failure of two antiepileptic drugs. Poor prognostic factors include a high initial seizure density, symptomatic aetiology, and presence of structural cerebral abnormalities, all of which can be identified early on. Among patients who have entered remission, many will remain seizure-free after antiepileptic drug treatment is withdrawn, suggesting that the underlying seizure generating factor has remitted. Whether some of these patients have entered remission “spontaneously” is contentious because, with effective pharmacotherapy for epilepsy in use for over 100 years, the natural history of untreated epilepsy is largely unknown. Circumstantial evidence, mostly arising from resource poor countries where antiepileptic drug treatment is not readily available, indicates that spontaneous remission may occur in up to 30% of cases. Observations from these complementary sources suggest that, at the population level, prognosis of newly diagnosed epilepsy may be broadly categorised into three groups: remission without treatment, remission with treatment only, and persistent seizures despite treatment. As understanding of the prognostic factors improves, the potential of a “prognostic group specific” management approach should be explored so that effective treatments may be used in a more rational and targeted fashion.
IMMUNOCHEMICAL STUDIES OF THE RH SYSTEM. I. ISOLATION AND CHARACTERIZATION OF ANTIBODIES.

1. A method of antibody isolation based upon absorption with intact erythrocytes, lysis of washed sensitized cells with digitonin, and acid elution of antibodies from hemoglobin-free stroma, has been described. 2. Antibody activity of eluates was correlated with the firmness of the erythrocytic antigen-antibody bond during absorption and with the amount of γ-globulin found in the eluate. 3. The γ-globulin in eluates was characterized by column chromatography, double gel diffusion, immunoelectrophoresis and analytical ultracentrifugation, and was measured by specific precipitin method. 4. Ficin treatment of red cells was found to increase the capacity of Rh antigenic sites to bind some Rh antibodies. On gradient DEAE chromatographic fractionation of sera, poorly binding Rh antibodies in one serum were recovered at a slightly higher buffer concentration than the more common firmly binding antibodies.
Remote supported trauma care: Understanding the situation from afar

We present results from a study of information needs when teleconsultation is used in trauma resuscitation. Three trauma team training sessions including 14 patient cases were observed together with field studies at emergency units. Technology probes like headcams and visualization of data usually available in the trauma room were used to better understand what information that is important or not for the remote expert to achieve a satisfactory Situation Awareness to support the trauma resuscitation. It was found that the two major information sources that the remote expert relies on are the vital signs and an overview, not necessarily with high video quality, of the team in the trauma room.
[Dietary exposure assessment of aflatoxin of foodstuff and edible oil from Shenzhen residents].

OBJECTIVE To assess the dietary exposure aflatoxin B1 and total aflatoxins of foodstuff and edible oil in Shenzhen residents. METHODS Aflatoxins in the samples were determined by the immuno-affinity column clean-up plus UPLC. The aflatoxin B1 and aflatoxins dietary exposure were calculated by the level of aflatoxins contamination in the food and consumption of dietary. RESULTS The average diary aflatoxin B1 dietary exposure of the man of the 2 to 6, 7 to 14, 15 to 50 and > 50 age group in Shenzhen were 0.320, 0.385, 0.401 and 0.398 ng/(kg BW x d), the results of the woman were 0.282, 0.222, 0.367 and 0.470 ng/(kg BW x d) respectively. The total average daily dietary aflatoxin B1 exposure of the man were 0.012, 0.015, 0.016 and 0.016 ng/(kg BW x d) about each age group. The results of the woman were 78.4, 167, 113 and 103 ng/(kg BW d). According to the the average levels of consumption and the high levels of consumption, the risk of AFB, of the man were 0.012,0.015, 0.016, 0. 016 and 3.0, 8.2, 4.1, 4.4 cancer patient per one hundred thousand, respectively. The results of the woman were 0.010, 0.009, 0.014, 0.018 and 2.9, 6.7, 4.4, 4.0 cancer patient per one hundred thousand, respectively. CONCLUSION 7 to 14 age group compared with adults age group face higher exposure levels. The rice and peanut oil are most primary aflatoxin dietary exposure sources in Shenzhen.
A generalized Input Admittance Criterion for resonance stability in electrical railway networks

We use dissipativity theory to propose a generalization of the Input Admittance Criterion - a widely used stability criterion in the railway industry. We investigate the theoretical implications of proposed changes to EN 50388 (Chapter 10) and show that the proposed changes are the most robust (and most conservative) among a class of similar stability criteria. In particular we show how stability can still be guaranteed even if the criterion EN 50388 (Chapter 10) is not met in practice - and in the process generalize the Input Admittance Criterion. We highlight the connection of the generalized Input Admittance Criterion with related problems in systems theory - viz the Nevanlinna-Pick interpolation problem, and the absolute stability problem.
Exercise and Atherogenesis

SMITH, J.K. Exercise and atherogenesis. Exerc. Sport Sci. Rev., Vol. 29, No. 2, pp 49–53, 2001. Atherogenesis involves the activation of endothelial cells and the egress of atherogenic T lymphocytes and monocytes into the intima. Exercise training contributes to the arrest and even reversal of atherosclerosis by modifying risk factors and by inducing an atheroprotective phenotype in endothelial cells and T cells.
Yield components and morphogenesis of Aruana grass in response to nitrogen supply

Areas with Aruana grass (Panicum maximum Jacq.) in Brazilian pastures, especially those used by sheep, have expanded due to yield and morphological characteristics of this grass that are favorable to these animals. Nevertheless, the knowledge concerning yield attributes of this grass in relation to nitrogen fertilization is very limited. The objective of this research was to evaluate yield and physiological attributes in this forage grass when grown in nutrient solutions containing N rates. The experiment was carried out in a greenhouse with plastic pots containing ground quartz as substrate, during the Spring season. Six N rates in the solution (14, 112, 210, 294, 378, and 462 mg L-1), with 70% N-NO3- and 30% N-NH4+ were tested. Experimental units were set up in a completely randomized block design, with four replications. Plants were harvested at 35 days after the seedlings were transplanted to the pots and again at 28 days after the first harvest. After the second harvest, the roots were taken from the substrate. In both growing periods, dry matter yield for plant tops and roots, leaf area, number of expanded green leaves, number of tillers, leaf appearance rate, and phyllochron were significantly affected by the N rates, and the data were adjusted to a second-order model. Aruana grass required high rates of N to show maximum response in those variables.
Effect of Velocity and Added Resistance on Selected Coordination and Force Parameters in Front Crawl

Schnitzler, C, Brazier, T, Button, C, Seifert, L, and Chollet, D. Effect of velocity and added resistance on selected coordination and force parameters in front crawl. J Strength Cond Res 25(10): 2681–2690, 2011—The effect of (a) increasing velocity and (b) added resistance was examined on the stroke (stroke length, stroke rate [SR]), coordination (index of coordination [IdC], propulsive phases), and force (impulse and peaks) parameters of 7 national-level front crawl swimmers (17.14 ± 2.73 years of swimming; 57.67 ± 1.62 seconds in the 100-m freestyle). The additional resistance was provided by a specially designed parachute. Parachute swimming (PA) and free-swimming (F) conditions were compared at 5 velocities per condition. Video footage was used to calculate the stroke and coordination parameters, and sensors allowed the determination of force parameters. The results showed that (a) an increase in velocity (V) led to increases in SR, IdC, propulsive phase duration, and peak propulsive force (p < 0.05), but no significant change in force impulse per cycle, whatever the condition (PA or F); and (b) in PA conditions, significant increases in the IdC, propulsive phase duration, and force impulse and a decrease in SR were recorded at high velocities (p < 0.05). These results indicated that, in the F condition, swimmers adapted to the change in velocity by modifying stroke and coordination rather than force parameters, whereas the PA condition enhanced the continuity of propulsive action and force development. Added resistance, that is, “parachute training,” can be used for specific strength training purposes as long as swimming is performed near maximum velocity.
Post-injury substance abuse among persons with brain injury and persons with spinal cord injury

Primary objective : To identify the patient population at greatest risk for post-injury adjustment problems, the present study independently examines and compares alcohol and drug use rates in patients with traumatic brain injury (TBI) and patients with spinal cord injury. Research design : The two samples were matched with regard to age, gender and mechanism of injury. The study provides a description of post-injury use rates for each population, and describes similarities and differences between the two groups. Methods and procedures : Participants included 30 consecutive Model Systems spinal cord injury (SCI) patients seen for follow-up neuropsychological testing between October 1996-June 1999. An equivalent number of Model Systems TBI patients were matched from a larger sample comprised of 440 consecutive hospital admissions, that returned for a 1-year follow-up neuropsychological evaluation between February 1989-December 1998. All participants were treated in an urban Level I trauma centre and associated inpatient rehabilitation programmes. Information regarding patient demographics, as well as pre- and post-injury psychiatric, employment, academic, criminal, and medical history was obtained via the General Health and History Questionnaire. Main outcomes and results : With regard to post-injury alcohol use rates, persons with spinal cord injury were more likely to drink on a daily basis. Although not statistically significant, pre-injury drinking rates differed from post-injury rates for both groups. With regard to illicit drug use, persons with TBI differed significantly from persons with SCI. A significant difference was also noted between pre-injury drug use and post-injury drug use for both groups. Conclusions : Persons who drink post-injury are unlikely to be 'light' or social drinkers. Either people choose to abstain completely or appear to use alcohol frequently.
GeTe Liner Stressor Featuring Phase-Change- Induced Volume Contraction for Strain Engineering of Sub-50-nm p-Channel FinFETs: Simulation and Electrical Characterization

We report the experimental demonstration of strained p-channel FinFETs featuring a GeTe liner stressor that exhibits very large volume contraction (~10%) during phase change. Conformally grown GeTe liner was formed on FinFETs with sub-50-nm gate length LG. When the GeTe liner changes phase from amorphous (α-GeTe) to polycrystalline (c-GeTe) state, it contracts and imparts very high compressive channel stress. A finite element method simulation was performed to study the channel stress in FinFETs, followed by a k · p calculation of Si valence band structure with the simulated strain tensors. The effective mass of the topmost valence band is reduced and the band dispersion between heavy-hole and light-hole sub-bands at Γ point increases with the effect of the strain induced by the GeTe liner. Significant drive current IDsat enhancement of 96% was observed for FinFETs with 50-nm c-GeTe liner stressor over the control devices. IDsat enhancement increases as LG reduces, showing good scalability of the GeTe liner stressor for possible application in future technology nodes.
piRNA pathway is not required for antiviral defense in Drosophila melanogaster

Significance In animals, one of the main forms of RNA interference involves Piwi-interacting RNAs (piRNAs), which protect genomes against the activity of transposable elements. Several groups have recently described piRNAs from viruses in mosquitoes and suggested their involvement in antiviral defense. To understand the extent to which the piRNA pathway contributes to antiviral defense in insects, we used Drosophila melanogaster and different viruses. Using high-throughput sequencing, we were unable to find any evidence of piRNAs from viruses in flies. Furthermore, flies lacking components of the piRNA pathway were not unusually susceptible to viral infection. Taken together, our results indicate that fundamental differences have arisen between the antiviral defenses of flies and mosquitoes since they last shared a common ancestor >200 Mya. Since its discovery, RNA interference has been identified as involved in many different cellular processes, and as a natural antiviral response in plants, nematodes, and insects. In insects, the small interfering RNA (siRNA) pathway is the major antiviral response. In recent years, the Piwi-interacting RNA (piRNA) pathway also has been implicated in antiviral defense in mosquitoes infected with arboviruses. Using Drosophila melanogaster and an array of viruses that infect the fruit fly acutely or persistently or are vertically transmitted through the germ line, we investigated in detail the extent to which the piRNA pathway contributes to antiviral defense in adult flies. Following virus infection, the survival and viral titers of Piwi, Aubergine, Argonaute-3, and Zucchini mutant flies were similar to those of wild type flies. Using next-generation sequencing of small RNAs from wild type and siRNA mutant flies, we showed that no viral-derived piRNAs were produced in fruit flies during different types of viral infection. Our study provides the first evidence, to our knowledge, that the piRNA pathway does not play a major role in antiviral defense in adult Drosophila and demonstrates that viral-derived piRNA production depends on the biology of the host–virus combination rather than being part of a general antiviral process in insects.
Status of group B streptococcal vaccine development

Streptococcus agalactiae (group B streptococcus, GBS) is a leading causal organism of neonatal invasive diseases and severe infections in the elderly. Despite significant advances in the diagnosis and treatment of GBS infections and improvement in personal hygiene standards, this pathogen is still a global health concern. Thus, an effective vaccine against GBS would augment existing strategies to substantially decrease GBS infection. In 2014, World Health Organization convened the first meeting for consultation on GBS vaccine development, focusing on the GBS maternal immunization program, which was aimed at reducing infections in neonates and young infants worldwide. Here, we review the history of GBS infections, the current vaccine candidates, and the current status of immunogenicity assays used to evaluate the clinical efficacy of GBS vaccines.
Adult asthma increases dementia risk: a nationwide cohort study

Background Studies on the association between adult asthma and dementia are few. We investigated the risk of dementia in patients diagnosed with adult asthma compared with that of people without asthma who were age and sex matched to the study patients. Methods We used data from the National Health Insurance Research Database. A total of 12 771 patients with newly diagnosed asthma between 2001 and 2003 were evaluated and 51 084 people without asthma were used as the comparison cohort. Cox proportional hazard regression analysis was used to measure the HR of dementia for the asthmatic cohort, compared with that of the non-asthmatic cohort. Results The HR of dementia was 1.27 (95% confidence interval (CI) 1.15 to 1.41) for the asthmatic cohort, compared with the non-asthmatic cohort after adjusting for age, sex, comorbidities, annual outpatient department visits and medicine used. The HR of dementia development increased substantially as frequency of asthma exacerbation and hospitalisation increased. Conclusions This nationwide cohort study suggests that the risk of dementia development is significantly increased in patients with asthma compared with that of the general population. In addition, dementia risk increases substantially with asthma exacerbation and hospitalisation frequency increases.
Melatonin Has the Potential to Alleviate Cinnamic Acid Stress in Cucumber Seedlings

Cinnamic acid (CA), which is a well-known major autotoxin secreted by the roots in cucumber continuous cropping, has been proven to exhibit inhibitory regulation of plant morphogenesis and development. Melatonin (MT) has been recently demonstrated to play important roles in alleviating plant abiotic stresses. To investigate whether MT supplementation could improve cucumber seedling growth under CA stress, we treated cucumber seeds and seedlings with/without MT under CA- or non-stress conditions, and then tested their effects on cucumber seedling growth, morphology, nutrient element content, and plant hormone. Overall, 10 μM MT best rescued cucumber seedling growth under 0.4 mM CA stress. MT was found to alleviate CA-stressed seedling growth by increasing the growth rates of cotyledons and leaves and by stimulating lateral root growth. Additionally, MT increased the allocation of newly gained dry weight in roots and improved the tolerance of cucumber seedlings to CA stress by altering the nutrient elements and hormone contents of the whole plant. These results strongly suggest that the application of MT can effectively improve cucumber seedling tolerance to CA stress through the perception and integration of morphology, nutrient element content and plant hormone signaling crosstalk.
Double burden of underweight and overweight among Bangladeshi adults differs between men and women: evidence from a nationally representative survey

Abstract Objective To estimate the prevalence of underweight and overweight among Bangladeshi adults and to determine if the double burden of underweight and overweight differs by gender and other socio-economic characteristics of individuals. Design We used data from the Bangladesh Demographic and Health Survey 2011. Multinominal logistic regression was used to examine associations between the different nutritional statuses of individuals and related determinants. Interaction effect was checked between gender and various socio-economic factors. Setting Nationwide, covering the whole of Bangladesh. Subjects Individuals aged >18 years (women, n 16 052; men, n 5090). Results Underweight was observed among 28·3 % of men and 24·4 % of women, whereas overweight was observed among 8·4 % of men and 16·9 % of women. The odds of being overweight were significantly lower among urban men (OR=0·46; 95 % CI 0·37, 0·57) compared with urban women, whereas the odds of being underweight were significantly higher among urban men (OR=1·33; 95 % CI 1·07, 1·64) compared with urban women. The odds of being overweight were lower among higher educated men (OR=0·48; 95 % CI 0·39, 0·58) and men of rich households (OR=0·45; 95 % CI 0·37, 0·54) compared with higher educated women and women of rich households, respectively. Conclusions There are important gender differences in the prevalence of underweight and overweight among the adult population in Bangladesh. Women with higher education, in rich and urban households have higher chances of being overweight and lower chances of being underweight compared with their male counterparts.
The Impact of Work‐related Risk on Nurses During the SARS Outbreak in Hong Kong

Severe acute respiratory syndrome (SARS) is a highly infectious disease, with high potential for transmission to close contacts, particularly among healthcare workers. This is the first systematic study investigating hospital nurses' physical and psychological health status and the kinds of healthcare used—stratified by the level of contact with SARS patients—during the 2003 outbreak in Hong Kong. Nurses in moderate-risk areas appeared to have more stress symptoms than those working in high-risk areas. It is essential to design hospital support systems and occupational health policy to promote the psychological well-being of nurses during future outbreaks of emerging infections.
Stress, coping, and hope

Hope is discussed in many literatures and from many perspectives. In this essay hope is discussed from the vantage of psychology and stress and coping theory. Hope and psychological stress share a number of formal properties: both are contextual, meaning‐based, and dynamic, and both affect well‐being in difficult circumstances. Two assumptions underlie this essay: (1) hope is essential for people who are coping with serious and prolonged psychological stress; and (2) hope is not a perpetually self‐renewing resource; it has peaks and valleys and is at times absent altogether. The relationship between hope and coping is dynamic and reciprocal; each in turn supports and is supported by the other. This relationship is illustrated with two adaptive tasks common across situations that threaten physical or psychological well‐being—managing uncertainty and coping with a changing reality. The essay describes ways in which coping fosters hope when it is at low ebb as well as ways in which hope fosters and sustains coping over the long term. Copyright © 2010 John Wiley & Sons, Ltd.