Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparative Study on Umbilical Cord Blood Lipid Profile in Normal and Low Birth Weight Neonates

Altered lipid levels are the recognized factors to cardiovascular disease in adults. This process is considered to begin in early life and progress silently over decades. An increase in low-density lipoprotein cholesterol (LDL-C) and decrease in high-density lipoprotein cholesterol (HDL-C) levels are associated with the atherosclerotic process, with its prodromal stages starting in early life. Objective of study to compare umbilical cord blood lipid profile between normal and low birth weight neonates. This was a cross sectional study carried out at neonatal Units of Department of Pediatrics, SMS Medical College, Jaipur from April 2015 to March 2016 included 110 babies each group of normal and low birth weight babies. Statistically significant difference ( P =< 0.001) was found between the mean TG and mean VLDL levels among the normal( TG = 641.61±18.05 mg/dl, VLDL =8.27±3.59mg/dl)and low birth weight babies( TG=60.44±36.63 mg/dl, VLDL = 12.72±8.95 mg/dl). No statistically significant difference was found between the mean values of TC, LDL and HDL among normal (TC=96.04±24.33mg/dl, LDL=64.71±21.02 mg/dl, HDL=23.05±7.043mg/dl) and low birth weight babies(TC=103.30±33.65mg/dl,LDL==67.22±30.93mg/dl,HDL=23.51±7.78mg/dl). Lipid (all types) levels were higher in LBW babies as compared to normal birth weight babies but the difference was statistically significant for TG and VLDL.
Phonon instabilities and the ideal strength of aluminum.

We have calculated the phonon spectra of aluminum as a function of strain using density functional perturbation theory for <110>, <100>, and <111> uniaxial tension, as well as relaxed <112>[111] shear. In all four cases, phonon instabilities occur at points away from the center of the Brillouin zone and intrude before the material becomes unstable according to elastic stability criteria. This is the first time the ideal strength of a metal has been shown to be dictated by instabilities in the acoustic phonon spectra. We go on to describe the crystallography of the unstable modes, all of which are shear in character. This work further suggests that shear failure is an inherent property of aluminum even in an initially dislocation-free perfect crystal.
Biting back: BiTE antibodies as a promising therapy for acute myeloid leukemia

The experience with gemtuzumab ozogamicin has highlighted both the potential value and limitations of antibodies in acute myeloid leukemia (AML). Recently, bispecific T-cell engager (BiTE) antibodies have emerged as a means to harness polyclonal cytotoxic T-cells and cause highly efficient lysis of targeted tumor cells. Promising early results have been obtained with the CD19-directed BiTE antibody, blinatumomab, in patients with acute lymphoblastic leukemia. A first candidate for AML is the CD33/CD3 molecule, AMG 330, for which several recent preclinical studies demonstrated high potency and efficacy in destroying CD33+ human AML cells. Many questions remain to be addressed, but BiTE antibodies may offer an exciting new tool in a disease for which the outcomes in many patients remain unsatisfactory.
Genotoxicity of acute and chronic gamma‐irradiation on zebrafish cells and consequences for embryo development

The effects of radiation on biological systems have been studied for many years, and it is now accepted that direct damage to DNA from radiation is the triggering event leading to biological effects. In the present study, DNA damage induced by acute or chronic irradiation was compared at the cellular (zebrafish [Danio rerio] cell line ZF4) and developmental (embryo) levels. Zebrafish ZF4 cells and embryos (at 3 h postfertilization) were exposed within ranges of acute doses (0.3–2 Gy/d) or chronic dose rates (0.1–0.75 Gy/d). DNA damage was assessed by immunodetection of γ‐H2AX and DNA‐PK (DNA double‐strand breaks) and the alkaline comet assay (DNA single‐strand breaks). Zebrafish embryo development and DNA damage were examined after 120 h. At low doses, chronic irradiation induced more residual DNA damage than acute irradiation, but embryo development was normal. From 0.3 Gy, a hyper‐radiosensitivity phenomenon compared to other species was shown for acute exposure with an increase of DNA damage, an impairment of hatching success, and larvae abnormalities. These results suggest a dose‐dependent correlation between unrepaired DNA damage and abnormalities in embryo development, supporting the use of DNA repair proteins as predictive biomarkers of ionizing radiation exposure. This could have important implications for environmental protection. Environ. Toxicol. Chem. 2011;30:2831–2837. © 2011 SETAC
Current best practice in rehabilitation in interstitial lung disease

Interstitial lung disease (ILD) is a group of chronic respiratory diseases characterized by dyspnoea on exertion and decline in health-related quality of life (HRQL). People with ILD experience significant exercise limitation with contributors that include ventilatory limitation, impaired gas exchange, decreased cardiac function and skeletal muscle dysfunction. Pulmonary rehabilitation (PR) is well established in patients with chronic obstructive pulmonary disease (COPD) as a means to overcome exercise limitation and improve activity-related dyspnoea. There is increasing evidence for similar effects of PR in people with ILD. This review discusses the evidence for PR in ILD, outlines the essential components of PR in this population, and highlights special considerations for exercise training in people with ILD. Possible future directions for PR research in people with ILD are explored.
Acculturation factors among Arab/Moslem women who live in the western culture

ii Dedication.iv Acknowledgments.v Vita.vi List of Tables.xiv List of Figures.xv Chapters: Introduction.1 1.1 Gender Views of Arab/Moslem Culture.3 1.2 Acculturation Level.6 1.3 Statement of the Problem.7 1.4 Research Questions.10 1.5 Dependent Variables.11 1.6 Significance of the Study to Social Work.16 2. Literature Review.20 2.1 Defining Culture.20 2.2 Acculturation.22 2.3 Assimilation.27 2.4 Similarities and differences between acculturation and
Generation of panoramic image based on planar image features using side-view in-vehicle camera

In this paper, we propose a method for generation of panoramic image suitable for a building wall surface using the side-view in-vehicle camera. In the proposed method, alignments and geometric normalizations are performed on the basis of planar features of the images. This allows no need for rigorous calibration for camera setting, such as camera postures and positions. Therefore, the proposed method is comparatively tolerant of image distortions which arise from the movement of a car. Experimental results show that the proposed method provides promising panoramic image.
Citation analysis cannot legitimate the strategic selection of excellence

In reaction to a previous critique(Opthof & Leydesdorff, 2010), the Center for Science and Technology Studies (CWTS) in Leiden proposed to change their old "crown" indicator in citation analysis into a new one. Waltman et al. (2011)argue that this change does not affect rankings at various aggregated levels. However, CWTS data is not publicly available for testing and criticism. In this correspondence, we use previously published data of Van Raan (2006) to address the pivotal issue of how the results of citation analysis correlate with the results of peer review. A quality parameter based on peer review was neither significantly correlated with the two parameters developed by the CWTS in the past (CPP/JCSm or CPP/FCSm) nor with the more recently proposed h-index (Hirsch, 2005). Given the high correlations between the old and new "crown" indicators, one can expect that the lack of correlation with the peer-review based quality indicator applies equally to the newly developed ones.
Numerical Simulation of Overtopping of Cnoidal Waves on a Porous Breakwater Using the Boussinesq Equations: Comparison with Solutions of the Navier-Stokes Equations

: We approximately obtain heights of cnoidal waves overtopping on a porous breakwater using both the one-layer Boussinesq equations (Vu et al., 2018) and the two-layer Boussinesq equations (Huynh et al., 2017). For cnoidal waves overtopping on a porous breakwater, we find through numerical experiments that the heights of cnoidal waves overtopping on a low-crested breakwater (obtained by the Navier-Stokes equations) are smaller than the heights of waves passing through a high-crested breakwater (obtained by the one-layer Boussinesq equations) and larger than the heights of waves passing through a submerged breakwater (obtained by the two-layer Boussinesq equations). As the cnoidal wave nonlinearity becomes smaller or the porous breakwater width becomes narrower, the heights of transmitting waves obtained by the one-layer and two-layer Boussinesq equations become closer to the height of overtopping waves obtained by the Navier-Stokes equations.
Machine Learning with Selective Word Statistics for Automated Classification of Citation Subjectivity in Online Biomedical Articles

- There is growing interest in automatically classifying author’s sentiment expressed within citation sentences in scientific literature to provide effective tools for researchers who are seeking relevant previous work or approaches for a certain research purpose. We propose an automated method of determining whether a given citation sentence contains an author’s subjective opinion (positive or negative) or objective factual information, as the first step to analyze and identify the citing author’s sentiments toward the cited external sources. Our method uses a support vector machine (SVM)-based text categorization technique to identify the subjective citations specifically toward Comment-on (CON) articles. CON, a MEDLINE ® citation field, indicates previously published articles commented on by authors of a given article expressing possibly complimentary or contradictory opinions. We introduce a bag of unigrams based on selective word statistics, which is derived from a text region of interest within a sentence containing a description of author’s reason of citation and lexical linguistic cues to build an input feature vector for the SVM classifier. Experiments conducted on a set of CON sentences collected from 414 different online biomedical journal titles show that the SVM classifier yields a comparable result for the proposed a bag of unigrams input feature selectively extracted from a text of interest, compared to another bag of unigrams from the entire sentence. Moreover, we achieve a significant performance boost of the SVM with an input feature vector combining two types of statistical bag of unigrams and sentiment word lexicon.
Diagnostic utility of serum and pleural fluid carcinoembryonic antigen, neuron-specific enolase, and cytokeratin 19 fragments in patients with effusions from primary lung cancer.

STUDY OBJECTIVES To assess the diagnostic values of carcinoembryonic antigen (CEA), neuron-specific enolase (NSE), and cytokeratin 19 fragments (CYFRA 21-1) as markers of pleurisy in primary lung cancer. DESIGN Prospective case-control study. SETTING A tertiary university hospital. PATIENTS Thirty-four patients with lung cancer and 16 patients with tuberculous pleurisy. MEASUREMENTS AND RESULTS Levels of CEA, NSE, and CYFRA 21-1 were measured by immunoassay in the serum and pleural fluid of patients with lung cancer and of patients with tuberculous pleurisy. Patients with lung cancer were found to have significantly higher serum and pleural fluid levels of CEA and CYFRA 21-1 than patients with tuberculous pleurisy. Using cutoff values of 5 ng/mL, 20 ng/mL, and 3.3 ng/mL for serum CEA, NSE, and CYFRA 21-1, respectively, the sensitivities and specificities of these tumor markers were as follows for differentiating malignant effusion from benign: CEA, 68% and 93%; NSE, 34% and 93%; and CYFRA 21-1, 45% and 100%. Using cutoff values of 5 ng/mL, 20 ng/mL, and 45 ng/mL for pleural fluid, the sensitivities and specificities were as follows: CEA, 82% and 94%; NSE, 36% and 94%; and CYFRA 21-1, 61% and 81%. A combination of pleural fluid CEA and NSE increased sensitivity and specificity. CONCLUSIONS In the diagnosis of malignant effusion associated with lung cancer, the determinations of CEA and NSE in pleural fluid could enhance diagnostic yield better than those of all three tumor markers.
Pore Characterization in Cross Section of Yellow Poplar (Liriodendron tulipifera) Wood

1) This study was conducted to analyze the pore structure of Yellow poplar. Cross-sectional surfaces of heartwood and sapwood of Yellow poplar (Liriodendron tulipifera) were observed by SEM, and the true density of the heartwood, intermediate wood and sapwood were measured by gas pycnometery, while gas permeability and pore size of heartwood, intermediate wood and sapwood were measured by capillary flow porometery. The pores were classified as through pore, blind pore and closed pore. It was determined that the permeability was increased due to the content and size of through pore being increased although the total porosity of specimen showed slight difference from pith to bark. The content of through pore porosity was 33.754 % of heartwood and 47.810 % of sapwood, showed an increasing trend from pith to bark, however, those for the blind pore porosity and closed pore porosity were 27.890 % and 19.492 % for heartwood and 19.447 % and 4.660 % for sapwood, showed a decreasing trend from pith to bark. The max pore size of specimens was increased by about 5 times from 5.927 μm to 31.334 μm, and mean flow pore size was increased by about 315 times from 0.397 μm to 12.437 μm from pith to bark.
Effects of environment and passive smoking on the respiratory health of children.

A cross-sectional survey was conducted to evaluate the possible effects of outdoor air pollution and of parental smoking on the respiratory health of children. A total of 3092 primary schoolchildren living in two polluted areas (an industrial town, Civitavecchia, and the city of Rome) and in a rural area, were chosen. A self-administered questionnaire was filled in by the parents of 2929 children (94.2%). A broad spectrum of respiratory symptoms and illnesses were taken as outcome variables. The frequency of most outcome variables was higher among children from the polluted areas than among those growing up in the non-polluted area (e.g. asthma: odds ratio (OR) = 1.4 for Civitavecchia, OR = 1.3 for Rome). Exposure to any passive smoking increased OR of having night cough (OR = 1.8), snoring (OR = 1.4), and respiratory infections during the first 2 years of life (OR = 1.3). A further increase in risk was observed in children whose mothers smoked or if both parents were smokers (asthma, OR = 1.5). When the separate and joint effects of the two exposures were studied, the patterns of OR did not suggest synergism between the two factors. The study indicates that both air pollution and passive smoking cause an increase in respiratory symptoms in children, although there would seem to be no additional effects of the two exposures together.
Resource-based view on corporate sustainable financial reporting and firm performance: evidences from emerging Indian economy

The purpose of the study is to find the impact of environmental, social and governance (ESG) disclosure on financial performance of firms in an emerging economy, India, using resource-based view. The financial performance of the firms was taken as the predicted variable. ESG disclosure scores showed negative association with the measures of firm performance, with relationship being moderately significant with return on assets. Environmental disclosure score was found to have significant inverse relationship with measures of both accounting performance (ROA) and marketing performance (Tobin's Q). Social performance disclosure has significant positive impact on firms' financial performance. Size of the firm has moderating role to play in determining the impact of social disclosure score on financial performance. Larger firms were found to be displaying higher capability to convert their social performance into competitive advantage. Firms in the sectors of healthcare and energy sectors have significant competitive advantage with higher environmental performance.
Diarylheptanoids Rich Fraction of Alnus nepalensis Attenuates Malaria Pathogenesis: In‐vitro and In‐vivo Study

Diarylheptanoids from Alnus nepalensis leaves have been reported for promising activity against filariasis, a mosquito‐borne disease, and this has prompted us to investigate its anti‐malarial and safety profile using in‐vitro and in‐vivo bioassays. A. nepalensis leaf extracts were tested in‐vitro against chloroquine‐sensitive Plasmodium falciparum NF54 by measuring the parasite specific lactate dehydrogenase activity. Among all, the chloroform extract (ANC) has shown promising anti‐plasmodial activity (IC50 8.06 ± 0.26 µg/mL). HPLC analysis of ANC showed the presence of diarylheptanoids. Efficacy and safety of ANC were further validated in in‐vivo system using Plasmodium berghei‐induced malaria model and acute oral toxicity in mice. Malaria was induced by intra‐peritoneal injection of P. berghei infected red blood cells to the female Balb/c mice. ANC was administered orally at doses of 100 and 300 mg/kg/day following Peter's 4 day suppression test. Oral administration of ANC showed significant reduction of parasitaemia and increase in mean survival time. It also attributed to inhibition of the parasite induced pro‐inflammatory cytokines as well as afford to significant increase in the blood glucose and haemoglobin level when compared with vehicle‐treated infected mice. In‐vivo safety evaluation study revealed that ANC is non‐toxic at higher concentration. Copyright © 2016 John Wiley & Sons, Ltd.
Actin-Dependent and -Independent Functions of Cortical Microtubules in the Differentiation of Arabidopsis Leaf Trichomes[W]

This investigation shows that genetic interactions of microtubule function in Arabidopsis trichome differentiation involve ANGUSTIFOLIA1 and F-actin. Detailed analyses of the cytoskeleton of growing trichomes in tortifolia2 distorted1 double mutants indicated that F-actin enhances microtubule dynamics and enables reorientation. Arabidopsis thaliana tortifolía2 carries a point mutation in α-tubulin 4 and shows aberrant cortical microtubule dynamics. The microtubule defect of tortifolia2 leads to overbranching and right-handed helical growth in the single-celled leaf trichomes. Here, we use tortifolia2 to further our understanding of microtubules in plant cell differentiation. Trichomes at the branching stage show an apical ring of cortical microtubules, and our analyses support that this ring is involved in marking the prospective branch site. tortifolia2 showed ectopic microtubule bundles at this stage, consistent with a function for microtubules in selecting new branch sites. Overbranching of tortifolia2 required the C-terminal binding protein/brefeldin A-ADP ribosylated substrate protein ANGUSTIFOLIA1, and our results indicate that the angustifolia1 mutant is hypersensitive to alterations in microtubule dynamics. To analyze whether actin and microtubules cooperate in the trichome cell expansion process, we generated double mutants of tortifolia2 with distorted1, a mutant that is defective in the actin-related ARP2/3 complex. The double mutant trichomes showed a complete loss of growth anisotropy, suggesting a genetic interaction of actin and microtubules. Green fluorescent protein labeling of F-actin or microtubules in tortifolia2 distorted1 double mutants indicated that F-actin enhances microtubule dynamics and enables reorientation. Together, our results suggest actin-dependent and -independent functions of cortical microtubules in trichome differentiation.
EHCM: A Multihop Aided Wireless Routing Protocol Based on Flow Priority in Smart Grid

In traditional smart grid, data aggregator (DA) and distribution box (DB) send the data collected by sensors to base station (BS) through cellular interface, which is called single-hop communication mode (SCM). In smart grid, different data packets have different delay priorities and the BS cannot satisfy all the delay requirements of different data because of limited resources through SCM. In order to meet the QoS requirements of different priority data, we propose a new scheme: enhanced hybrid communication mode (EHCM), by introducing multihop communication mode (MCM) into this scenario to improve the network's performance by adding another wireless interface on each node. Our scheme EHCM consists of two parts: the intracell data transmission and the cell edge data transmission. In the first part, we propose a solution to choose a relay node according to the node's energy consumption and its residual energy and a solution to forward packets based on its priority and residual lifetime (RLT). In the second part, the tasks of data transmission can be delivered from the congested DB nodes to the adjacent idle ones to provide optimal performance. At last, the simulation shows that our scheme can satisfy the performance requirement of smart grid.
Biochemical Assessment of Paget's Disease of Bone

Biochemical measurements of bone turnover provide an objective assessment of disease activity and the response to treatment. Alkaline phosphatase is the best characterized of the bone turnover markers and reflects the extent and activity of Paget's disease. However, in addition to bone‐specific alkaline phosphatase (Bone ALP), there is also osteocalcin (OC) and procollagen type 1 N‐terminal propeptide (P1NP) as formation markers. A variety of telopeptides (C‐terminal telopeptide of type I collagen, [CTX], N‐telopeptide of type I collagen [NTX]) or cross‐link breakdown products of type 1 collagen can be used to assess bone resorption. Total alkaline phosphatase (Total ALP), Bone ALP, and P1NP all perform similarly in diagnosis and in evaluating the response to treatment, but the general availability, low interassay variation, and inexpensiveness of Total ALP makes it the best test for routine use. Measurement of the biological variability of the different markers in stable, untreated Paget's disease indicates how great a change (critical difference) is needed to define a true alteration in disease activity. Bone ALP, P1NP, and NTX show the highest therapy induced change/critical difference ratio during antiresorptive treatment. Some of the resorption markers show more complex changes in response to treatment. Pyridinoline (PYD) or deoxypyridinoline (DPD) cross‐links of type 1 collagen are excreted in urine either as free or as peptide bound moieties, but it is the latter which decrease by the greatest amount in response to bisphosphonate therapy. Newly formed type 1 collagen contains an aspartyl‐glycine motif (αCTX), which undergoes spontaneous isoaspartyl formation to βCTX as the bone ages. In untreated Paget's disease, the αCTX is raised proportionately more (16‐fold) than βCTX (3‐fold) and decreases in response to bisphosphonate therapy to a greater extent than βCTX (measured in the sCTX assay). As bisphosphonates have become more potent, the aim of treatment has shifted toward the achievement of a rate of bone turnover in the lower part of the reference range. This is important because the duration of remission of disease activity is strongly determined by the post treatment nadir bone turnover.