Miracle-dz/UniFAR-FTUs huggingface dataset:
Racial/ethnic differences in rates of depression among preretirement adults.

OBJECTIVES We estimated racial/ethnic differences in rates of major depression and investigated possible mediators. METHODS Depression prevalence rates among African American, Hispanic, and White adults were estimated from a population-based national sample and adjusted for potential confounders. RESULTS African Americans (odds ratio [OR] = 1.16, 95% confidence interval [CI] = 0.93, 1.44) and Hispanics (OR = 1.44, 95% CI = 1.02, 2.04) exhibited elevated rates of major depression relative to Whites. After control for confounders, Hispanics and Whites exhibited similar rates, and African Americans exhibited significantly lower rates than Whites. CONCLUSIONS Major depression and factors associated with depression were more frequent among members of minority groups than among Whites. Elevated depression rates among minority individuals are largely associated with greater health burdens and lack of health insurance, factors amenable to public policy intervention.
Inorganic constituents of cerebrospinal fluid: The ultrafiltration of calcium and magnesium from human sera.

IN a recent paper McCance and Watchorn [1930-31] reported a preliminary investigation of the ultrafiltration of magnesium from serum. A further sixty cases have now been examined, including those with normal, subnormal and increased levels of serum-magnesium. No attempt has been made to study specifically any particular disease, as the main object has been to investigate the ultrafiltration of magnesium over a wide range of naturally occurring serum values. It is therefore impossible to deal statistically with separate diseases although some reference will be made to one or two, particularly nephritis. Normal pregnancy also will be disoussed. As in the preliminary paper, calcium has been determined simultaneously in most cases for comparative purposes, although ultrafiltration of calcium from serum has already been extensively studied [for references see McCance and Watchorn, 1930-31].
Effects of stratospheric variability on El Niño teleconnections

The effects of the tropical Pacific El Niño Southern Oscillation (ENSO) phenomenon are communicated to the rest of the globe via atmospheric teleconnections. Traditionally, ENSO teleconnections have been viewed as tropospheric phenomena, propagating to higher latitudes as Rossby waves. Recent studies, however, suggest an influence of the stratosphere on extra-tropical ENSO teleconnections. The stratosphere is highly variable: in the tropics, the primary mode of variability is the quasi-biennial oscillation (QBO), and in the extra-tropics sudden stratospheric warmings (SSWs) regularly perturb the mean state. Here, we conduct a 10-member ensemble of simulations with a stratosphere-resolving atmospheric general circulation model forced with the observed evolution of sea surface temperatures during 1952–2001 to examine the effects of the QBO and SSWs on the zonal-mean circulation and temperature response to El Niño, with a focus on the northern extra-tropics during winter. We find that SSWs have a larger impact than the QBO on the composite El Niño responses. During El Niño winters with SSWs, the polar stratosphere shows positive temperature anomalies that propagate downward to the surface where they are associated with increased sea-level pressure over the Arctic. During El Niño winters without SSWs, the stratosphere and upper troposphere show negative temperature anomalies but these do not reach the surface. The QBO modulates the El Niño teleconnection primarily in winters without SSWs: the negative temperature anomalies in the polar stratosphere and upper troposphere are twice as large during QBO West compared to QBO East years. In addition, El Niño winters that coincide with the QBO West phase show stronger positive sea-level pressure anomalies over the eastern Atlantic and Northern Europe than those in the QBO East phase. The results imply that the stratosphere imparts considerable variability to ENSO teleconnections.
Fracture resistance of roots endodontically treated with a new resin filling material.

BACKGROUND The authors evaluated the fracture resistance of endodontically treated teeth filled with either gutta-percha or a new resin-based obturation material. METHODS The authors prepared and randomly divided 80 single-canal extracted teeth into five groups: lateral and vertical condensation with gutta-percha, lateral and vertical condensation with the new resin-based obturation material, and a control group with no filling material. The specimens were stored in 100 percent humidity for two weeks, mounted in polyester resin and loaded to failure. RESULTS The authors found statistically significant differences among the experimental groups (P < .05). The groups with the new material displayed higher mean fracture loads and the gutta-percha groups lower mean fracture load values than the control unfilled group. However, the differences were not significant. The groups with the new material displayed significantly higher mean fracture loads than gutta-percha groups independent of the filling technique used. CONCLUSIONS Filling the canals with the new resin-based obturation material increased the in vitro resistance to fracture of endodontically treated single-canal extracted teeth when compared with standard gutta-percha techniques. CLINICAL IMPLICATIONS; If other properties of the new resin-based obturation material compare favorably with those of gutta-percha for filling the root canal, it should be considered as a replacement for gutta-percha, as the results of this study indicate that it could provide enhanced resistance to tooth fracture.
Transferrin Receptor Expression in Normal, Iron‐deficient and Iron‐overloaded Rats

The distribution of transferrin receptor (TfR) positive cells and their staining intensity were examined in the liver, duodenum, pancreas, spleen, kidney and brain of iron deficient, iron‐overloaded and normal Wistar rats to elucidate the regulatory effects of iron on TfR expression in vivo. Iron deficiency was produced by an iron deficient food and water regimen, and iron overload by repeated intraperitoneal injections of ferric nitrilotriacetate (Fe3‐NTA) for 12 weeks. In iron deficient rats, levels of hemoglobin (Hb= 5.9 ± 0.7) and serum iron (Sl = 29.9 ± 4.4) were lower, and total iron binding capacity (TIBC = 624.4 ± 72.7) was higher than in normal rats (Hb = 15.6 ± 0.9, Sl = 206.5 # 20.5, TIBC = 416.0 ± 56.0), and Wee versa for SI (217.7 ± 15.5) and TIBC (307.1 ± M45.4) in iron‐overloaded rats. In normal rats, TfR positive granules were observed in hepatocytes and Kupffer cells of the liver, absorptive epithelium of the duodenum, acinar and Langerhans islet cells of the pancreas, macrophages and red pulp erythro‐blasts of the spleen, and distal convoluted tubular epithelium of the kidney. Although the tissue distribution pattern of TfR positive cells was similar in normal, iron deficient and iron overloaded rats, the staining intensity and number of TfR positive cells were obviously higher in iron deficient, and lower in iron overloaded rats. We conclude that TfR expression is negatively regulated by the tissue concentration of iron. Acta Pathol Jpn 39: 759‐764, 1989.
Foot placement modifies kinematics and kinetics during drop jumping.

PURPOSE Sprinting, bouncing, and spontaneous landings are associated with a forefoot contact whereas walking, running, and jumping are associated with heel-toe foot placement. Because such foot placement strategies influence landing mechanics or the ensuing performance, the purpose of this work was to compare lower extremity kinematics and kinetics and muscle activation patterns between drop vertical jumps performed with heel-toe (HTL) and forefoot (FFL) landings. METHODS Ten healthy male university students performed two types of drop jump from a 0.4-m high box placed 1.0-m from the center of the force plate. They were instructed to either land first on the ball of the feet without the heels touching the ground during the subsequent vertical jump, i.e., forefoot landing jump (FFL), or to land on the heels followed by depression of the metatarsals, i.e., heel-toe landing jump (HTL). Three successfully performed trials per jump type were included in the analysis. The criteria for selection of the correct jumps was proper foot position at contact as judged from video records and the shape of force-time curve. RESULTS The first peak and second peak determined from the vertical force-time curves were 3.4 times greater and 1.4 times lower for HTL compared with those with FFL (P<0.05). In the flexion phase of HTL, the hip and knee joints contributed 40% and 45% to the total torque, whereas during FFL the greatest torque contributions were 37% for both the knee and ankle joints. During the extension phase, the greatest torque contributions to the total torque were 41% and 45% by the knee and ankle joints during HTL and 34% and 55% during FFL. During the flexion phase, power production was 20% greater (P<0.05) in HTL than in FFL, whereas during the extension phase power production was 40% greater in FFL than in HTL. In the flexion phase of HTL the hip and knee joints produced the greatest power, and during the extension phase the knee and ankle joints produced the greatest power. In contrast, during both the flexion and extension phases of FFL, the knee and ankle joints produced the greatest power. The EMG activity of gluteus, vastus lateralis, and plantar flexor muscles was similar between HTL and FFL in most cases except for the greater vastus lateralis EMG activity during precontact phase in HTL than in FFL and the greater gastrocnemius activity in FFL than in HTL. CONCLUSION Foot placement strategy modifies the individual joint contributions to the total power during drop jumping.
Ambulatory foot contact monitor to estimate metabolic cost of human locomotion.

The rate of metabolic energy expenditure during locomotion (Mloco) is proportional to body weight (Wb) divided by the time during each stride that a single foot contacts the ground (tc) (Nature Lond. 346: 265-267, 1990). Using this knowledge, we developed an electronic foot contact monitor. Our objective was to derive and cross-validate an equation for estimation Mloco from Wb/tc. Twelve males were tested [age = 19.4 +/- 1.4 (SD) yr, Wb = 78.4 +/- 8.0 kg] during horizontal treadmill walking (0.89, 1.34, and 1.79 m/s) and running (2.46, 2.91, and 3.35 m/s). Measured Mloco was defined as the total rate of energy expenditure, measured by indirect calorimetry, minus the estimated rate of resting energy expenditure. The equation to estimate Mloco was derived in six randomly selected subjects: Mloco = 3.702. (Wb/tc) - 149.6 (r2 = 0.93). Cross-validation in the remaining six subjects showed that estimated and measured Mloco were highly correlated (r2 = 0.97). The average individual error between estimated and measured Mloco was 0% (range -22 to 29%). In conclusion, Mloco can be accurately estimated from Wb and measurements of tc made by an ambulatory foot contact monitor.
Longitudinal Study of Calcium Intake, Physical Activity, and Bone Mineral Content in Infants 6–18 Months of Age

Although increased physical activity early in life is recommended for optimizing bone health, no controlled trials on the effect of activity on bone mass accretion during periods of rapid growth have been reported. The purpose of this study was to determine whether infants randomized to a 1 year gross motor activity program had a greater bone mass accretion than infants randomized to a fine motor activity program. The gross motor program included activities that focused on loading the skeleton and were performed for 15–20 minutes/day, 5 days/week by study personnel. Infants (n = 72) were enrolled at 6 months of age, and total body bone mineral content (BMC), 3‐day diet records, and activity levels were obtained at 6, 9, 12, 15, and 18 months. BMC was associated with weight, length, and bone area at all ages and correlated with earlier calcium intakes. Calcium intake appeared to modify the effect of gross motor activity on bone mass accretion; infants in both groups had similar bone accretion at moderately high calcium intakes, but at low calcium intakes infants in the gross motor program had less bone accretion than infants in the fine motor program. Compliant infants in the gross motor group had lower BMC at 18 months compared with noncompliant infants. These results indicate that BMC in infants is related to calcium intake, and we speculate that participation in a gross motor program during rapid bone growth may lead to reduced bone accretion in the presence of a moderate to moderately low calcium intake.
Extended long-term culture reveals a highly quiescent and primitive human hematopoietic progenitor population.

Long-term culture-initiating cells (LTC-IC) are hematopoietic progenitors able to generate colony-forming unit-cells (CFU) after 5 to 8 weeks (35 to 60 days) of culture on bone marrow (BM) stroma and represent the most primitive progenitors currently detectable in vitro. We have recently reported that long-term cultures initiated with CD34+CD38- cells from BM or cord blood are able to continue generating CFU for at least 100 days, ie, beyond the standard LTC-IC period. In this report, single-cell cultures from cord blood and retroviral marking of cord blood and BM were used to study whether the subpopulation of CD34+CD38- cells able to generate CFU beyond 60 days ("extended long-term culture-initiating cells" or ELTC-IC) are functionally distinct from LTC-IC in terms of timing of initial clonal proliferation and generative capacity. All cord blood LTC-IC formed clones of greater than 50 cells by day 30. In contrast, cord blood ELTC-IC proliferated later in culture, 50% forming clones after day 30. Although efficient retroviral marking of LTC-IC was seen (25% to 45%), marking of ELTC-IC was inefficient (< 1%), consistent with a more quiescent progenitor population. There was a positive correlation between time of clonal proliferation and generative capacity. ELTC-IC generated threefold to fourfold more progeny than did LTC-IC (P < .002). These studies show that there is a functional hierarchy of progenitors in long-term culture which correlates with their level of quiescence. By extending the LTC-IC assay, a more primitive progenitor may be studied that may be functionally closer to the human long-term repopulation stem cell in vivo.
g_membed: Efficient insertion of a membrane protein into an equilibrated lipid bilayer with minimal perturbation

To efficiently insert a protein into an equilibrated and fully hydrated membrane with minimal membrane perturbation we present a computational tool, called g_membed, which is part of the Gromacs suite of programs. The input consists of an equilibrated membrane system, either flat or curved, and a protein structure in the right position and orientation with respect to the lipid bilayer. g_membed first decreases the width of the protein in the xy‐plane and removes all molecules (generally lipids and waters) that overlap with the narrowed protein. Then the protein is grown back to its full size in a short molecular dynamics simulation (typically 1000 steps), thereby pushing the lipids away to optimally accommodate the protein in the membrane. After embedding the protein in the membrane, both the lipid properties and the hydration layer are still close to equilibrium. Thus, only a short equilibration run (less then 1 ns in the cases tested) is required to re‐equilibrate the membrane. Its simplicity makes g_membed very practical for use in scripting and high‐throughput molecular dynamics simulations. © 2010 Wiley Periodicals, Inc. J Comput Chem, 2010
Nutritional Practices among Ethnic Minorities and Child Malnutrition in Mountainous Areas of Central Vietnam

Background: Despite the success of National Action Plan on Nutrition program in reducing malnutrition among children under 5 years old in Vietnamin recent years, the rate of malnutrition inVietnamremains higher than that rate in other surrounding countries. The rate is especially high in mountainous areas. This study aims to explore the association between the mother’s nutrition care practice and the nutritional status of their children. Methods: 400 Children under 5 years of age and their mothers from Thanh Hoa—a Northern Province of Vietnam were included in this survey. Weight and height of the children were measured. Information related to the mother’s knowledge and practices pertaining to child health care and nutrition was collected. Results: The malnutrition rate was 29.3% by weight for age score (WAZ), 28.3% by height for age score (HAZ) and 10.0% by weight for height score (WHZ). 27.3% of mothers discarded the colostrum milk. 21.3% of children were fed with chewing rice before breastfeeding. Exclusive breastfeeding up to four months was 17.8% and exclusive breastfeeding rates for 6 months or more was 8.6%. Weaning practice before four months of age was 53.7%. There was an association between malnutrition with mother’s ethnic group, and the frequency of consumption of protein rich food. Conclusion: Malnutrition of ethnic minority children under five years of age is still a public health problem in the central mountainous areas ofVietnam. Inappropriate breastfeeding and weaning practice among ethnic minority women were associated with this high rate. Further effort should continue to improve the nutrition status of ethnic minority children under 5 years of age. Customized, culturally adapted interventions for ethnic minority women to strengthen their nutrition care knowledge, attitude and practice, especially breastfeeding and weaning practice are the key to achieving better nutrition status of their children.
Working Conditions in Carpet Weaving Workshops and Muscu-loskeletal Complaints among Workers in Tabriz - Iran.

BACKGROUND Carpet weaving operations usualy involve poor working conditions that can lead to the development of musculoskeletal disorders (MSDs). This study investigated MSDs among car¬pet weavers in relation to working conditions from workers' view in Tabriz City, Northwest Iran. METHODS This cross-sectional and descriptive study was conducted in city of Tabriz, Iran. Data were col¬lected using interviews and questionnaires. The study population consisted of 200 randomly selected healthy weavers from twenty five active carpet weaving workshops. RESULTS The results showed a high prevalence of musculoskeletal problems among the study population. The most commonly affected body areas were neck, lower back, ankles/feet, hands/wrists, upper back, shoulders and knees, respectively. More than half of the weavers were not satisfied with the thermal con¬dition, noise level and cleanliness of the air in the workshops. The result indicated a significant relation¬ship between upper back symptoms and daily working time and between lower back symptoms and the numbers of rows of knots woven in a day. Weavers' satisfaction with hand tools shape and thermal condi¬tion of the workshops were associated with lower back symptoms, whereas satisfaction with weaving looms were associated with upper back complaints. CONCLUSION The poor working condition of hand-woven carpet workshops such as environmental con¬ditions and work station design and tools should be the subject of ergonomics interventions.
Automatic Sequences and Generalised Polynomials

Abstract We conjecture that bounded generalised polynomial functions cannot be generated by finite automata, except for the trivial case when they are ultimately periodic. Using methods from ergodic theory, we are able to partially resolve this conjecture, proving that any hypothetical counterexample is periodic away from a very sparse and structured set. In particular, we show that for a polynomial $p(n)$ with at least one irrational coefficient (except for the constant one) and integer $m\geqslant 2$, the sequence $\lfloor p(n)\rfloor \hspace{0.2em}{\rm mod}\hspace{0.2em}m$ is never automatic. We also prove that the conjecture is equivalent to the claim that the set of powers of an integer $k\geqslant 2$ is not given by a generalised polynomial.
Length of Catheter Use After Hysterectomy as a Risk Factor for Urinary Tract Infection

Objectives The aims of this study were to determine the effect of length of postoperative catheterization on risk of urinary tract infection (UTI) and to identify risk factors for postoperative UTI. Methods This was a retrospective case-control study. Demographic and perioperative data, including duration of indwelling catheter use and postoperative occurrence of UTI within 30 days of surgery, were analyzed for hysterectomies using the Michigan Surgical Quality Collaborative database. Catheter exposure was categorized as low—no catheter placed/catheter removed the day of surgery, intermediate—catheter removed postoperative day 1, high—catheter removal on postoperative day 2 or later, or highest—patient discharged home with catheter. A multivariable logistic regression model was developed to identify factors associated with UTI. An interaction term was included in the final model. Results Overall, UTI prevalence was 2.3% and increased with duration of catheter exposure (low: 1.3% vs intermediate: 2.1% vs high: 4.1% vs highest: 6.5%, P < 0.0001). High (odds ratio [OR] = 2.54 [1.51–4.27]) and highest (OR = 3.39 [1.86–6.17]) catheter exposure, operative time (OR = 1.15 [1.03–1.29]), and dependent functional status (OR = 4.62 [1.90–11.20]) were independently associated with UTI. Women who had a vaginal hysterectomy with sling/pelvic organ prolapse repair were more likely to have a UTI than those who had a vaginal hysterectomy alone (OR = 2.58 [1.10–6.07]) and more likely to have a UTI than women having an abdominal or laparoscopic hysterectomy with a sling/pelvic organ prolapse repair (OR = 2.13 [1.12–4.04]). Conclusions Length of catheterization and operative time are modifiable risk factors for UTI after hysterectomy. An interaction between vaginal hysterectomy and concomitant pelvic reconstruction increases the odds of UTI.
Is Earnings Quality Associated with Corporate Social Responsibility?

Socially responsible firms are believed to behave in a responsible manner to restrict earnings management and thus deliver more reliable and transparent financial information to investors. We test this hypothesis by predicting a higher quality of financial reporting for socially responsible firms in the Korean market. The entire sample analysis provides evidence for the hypothesis in the use of discretionary accruals as proxy variables for the quality of financial reporting. However, our sub-sample analysis indicates that such weak support is driven by a group of environmentally sensitive firms and the affiliates of large family-owned conglomerates, or chaebol. Socially responsible firms are less likely to be involved with earnings management in the group of non-environmentally sensitive industries and non-chaebol affiliates. These firms provide a better quality of financial reporting in terms of both the use of discretionary accruals and real activity manipulations. In line with recent studies, our findings suggest that ethical concerns in producing high-quality financial reports rely significantly on firm characteristics.