Miracle-dz/UniFAR-FTUs huggingface dataset:
Farmers’ risk attitudes to influence the productivity and planting decision: A case of rice and maize cultivation in rural Uganda

The effects of Ugandan farmers’ attitudes toward risk on their decisions about rice production are closely analysed and discussed. A three-step procedure is proposed: 1) farmers’ characteristics determine farmers’ risk attitudes, 2) their risk attitudes influence yield, and 3) yield affects decisions on acreage. This procedure is based on the assumption that acreage decisions are a reflection of farmers’ actual yields, which are associated with risk-averting farming practices. The estimation results show that age and religion are significantly correlated with farmers’ risk attitude, that risk-averse farmers perform better in terms of yield, and that higher yields subsequently increase acreage for production. These attitudes partly account for the diminishing increase in rice production. The results imply that effective ways to increase rice acreage are to increase the potential yield of rice and to promote rice cultivation for lands that are suited to rice cultivation.
Recent advances in managing septal defects: ventricular septal defects and atrioventricular septal defects

This review discusses the management of ventricular septal defects (VSDs) and atrioventricular septal defects (AVSDs). There are several types of VSDs: perimembranous, supracristal, atrioventricular septal, and muscular. The indications for closure are moderate to large VSDs with enlarged left atrium and left ventricle or elevated pulmonary artery pressure (or both) and a pulmonary-to-systemic flow ratio greater than 2:1. Surgical closure is recommended for large perimembranous VSDs, supracristal VSDs, and VSDs with aortic valve prolapse. Large muscular VSDs may be closed by percutaneous techniques. A large number of devices have been used in the past for VSD occlusion, but currently Amplatzer Muscular VSD Occluder is the only device approved by the US Food and Drug Administration for clinical use. A hybrid approach may be used for large muscular VSDs in small babies. Timely intervention to prevent pulmonary vascular obstructive disease (PVOD) is germane in the management of these babies. There are several types of AVSDs: partial, transitional, intermediate, and complete. Complete AVSDs are also classified as balanced and unbalanced. All intermediate and complete balanced AVSDs require surgical correction, and early repair is needed to prevent the onset of PVOD. Surgical correction with closure of atrial septal defect and VSD, along with repair and reconstruction of atrioventricular valves, is recommended. Palliative pulmonary artery banding may be considered in babies weighing less than 5 kg and those with significant co-morbidities. The management of unbalanced AVSDs is more complex, and staged single-ventricle palliation is the common management strategy. However, recent data suggest that achieving two-ventricle repair may be a better option in patients with suitable anatomy, particularly in patients in whom outcomes of single-ventricle palliation are less than optimal. The majority of treatment modes in the management of VSDs and AVSDs are safe and effective and prevent the development of PVOD and cardiac dysfunction.
Sesquiterpene lactone 6-O-angeloylplenolin reverses vincristine resistance by inhibiting YB-1 nuclear translocation in colon carcinoma cells

Multidrug resistance (MDR) is a major obstacle to cancer chemotherapy efficacy. In the present study, 6-O-angeloylplenolin repressed the overexpression of ATP binding cassette subfamily B member 1 (MDR1) and increasing the intracellular concentration of anticancer drugs. A reduction in P-glycoprotein expression (encoded by MDR1) was observed in parallel with a decline in mRNA expression in vincristine-resistant HCT (HCT-8/VCR) cells treated with 6-O-angeloylplenolin. In addition, 6-O-angeloylplenolin suppressed the activity of the MDR1 gene promoter. Treatment with 6-O-angeloylplenolin also decreased the amount of the specific protein complex that interacted with the MDR1 gene promoter in HCT-8/VCR cells, potentially leading to the suppression of MDR1 expression. Treatment with 6-O-angeloylplenolin inhibited the nuclear translocation of Y-box binding protein-1 in HCT-8/VCR cells treated with 6-O-angeloylplenolin, contributing to the negative regulation of MDR1. Finally, 6-O-angeloylplenolin reversed VCR resistance in an HCT/VCR xenograft model. In conclusion, 6-O-angeloylplenolin exhibited a MDR-reversing effect by downregulating MDR1 expression and could represent a novel adjuvant agent for chemotherapy.
Thermal Hydraulics of Helium-Cooled Finger-Type Divertors at Higher Incident Heat Fluxes

Abstract Over the last decade, a number of studies at the Georgia Institute of Technology (GT) have evaluated the thermal hydraulics of the design of the helium-cooled modular divertor with multiple jets (HEMJ) originally developed at the Karlsruhe Institute of Technology. Using the GT helium loop, a test section of a single HEMJ finger heated by a radio-frequency (rf) induction heater was studied at near prototypical condition at pressures of ~10 MPa, maximum mass flow rates of 8 g/s, and maximum helium inlet temperatures Ti of 425°C. The area-averaged cooled surface temperature was estimated from embedded thermocouple measurements. This, together with the average incident heat flux , was used to determine the average heat transfer coefficient and the corresponding Nusselt number over the cooled surface. The normalized pressure loss coefficient KL was determined from the pressure drop measured across the test section. The helium loop was modified last year by enclosing the test section and heater within an argon-filled stainless steel chamber to minimize oxidation of the tungsten-alloy test section. Initial results, when extrapolated to prototypical conditions, suggested that was about 20% higher than our previous results. However, the maximum heat flux for these results was less than 3 MW/m2 due to rf coupling with the steel chamber walls. The chamber was then recently upgraded to a glass–stainless steel enclosure with modified feedthroughs for the induction heater connections to minimize this coupling. With this upgrade, a maximum incident heat flux = 8.1 MW/m2 was achieved. This work presents experimental estimates and correlations for and KL at higher heat fluxes. These results provide greater confidence when estimating the maximum heat flux that can be accommodated by the HEMJ at fully prototypical conditions. Finally, preliminary metrology results for the test section used to experimentally study the simplified flat design variant of the HEMJ are presented as part of an effort to resolve recently reported discrepancies between experimentally estimated and numerically simulated
Four immunohistochemical assays to measure the PD-L1 expression in malignant pleural mesothelioma

Immune checkpoint inhibitors (ICIs) targeting the PD-1/PD-L1 pathway are expected to be a novel therapy for combating future increases in numbers of malignant pleural mesothelioma (MPM) patients. However, the PD-L1 expression, which is a predictor of the response to ICIs, is unclear in MPM. We studied the PD-L1 expression using four immunohistochemical assays (SP142, SP263, 28-8 and 22C3) in 32 MPM patients. The PD-L1 expression in tumor cells and immune cells was evaluated to clarify the rate of PD-L1 expression and the concordance among the four assays in MPM. The positivity rate of PD-L1 expression was 53.1% for SP142, 28.1% for SP263, 53.1% for 28-8, and 56.3% for 22C3. Nine cases were positive and 10 were negative for all assays. Discordance among the four assays was found in 13 cases. The concordance rates between SP142 and 22C3 and between 28-8 and 22C3 were the highest (84.4%). The concordance rates between SP263 and the other three assays were low (71.9% to 75.0%). The PD-L1 expression in MPM was almost equivalent for three of the assays. Given the cut-off values set in our study, these findings suggested that these assays, except for SP263, can be used for accurate PD-L1 immunostaining in MPM.
Left atrial size, atrial function and left ventricular diastolic function in cats with hypertrophic cardiomyopathy.

OBJECTIVES To describe left atrial size, left atrial volume, left atrial function and left ventricular diastolic function in healthy cats and those with hypertrophic cardiomyopathy without and with congestive heart failure. METHODS A retrospective study of 61 client-owned, 21 healthy, 21 asymptomatic hypertrophic cardiomyopathy and 19 with hypertrophic cardiomyopathy and congestive heart failure cats. Data were retrieved from clinical records and echocardiography archives. Left atrial diameter and volumes were measured. Left atrial function was investigated using changes in diameter (fractional shortening) and volume (Simpson's method; left atrial ejection fraction). Conventional echocardiographic indices of left ventricular diastolic function were recorded. RESULTS Left atrial diameter and left atrial volume measurements were significantly higher in hypertrophic cardiomyopathy with congestive heart failure cats compared with asymptomatic hypertrophic cardiomyopathy and healthy cats (P < 0·001). Left atrial passive, active and complete ejection fraction distinguished between hypertrophic cardiomyopathy with congestive heart failure and asymptomatic hypertrophic cardiomyopathy (P < 0·001). Hypertrophic cardiomyopathy with congestive heart failure cats had significantly lower mitral A wave velocity (P = 0·016) and atrial complete emptying based on diameter and volume measurements (P = 0·008 and P < 0·001, respectively) compared with asymptomatic hypertrophic cardiomyopathy cats. CLINICAL SIGNIFICANCE Left atrial volume is obtainable by echocardiography in cats. Left atrial volume and atrial function may indicate chronicity and severity of diastolic dysfunction associated with hypertrophic cardiomyopathy and congestive heart failure. Left atrial function was reduced in cats with hypertrophic cardiomyopathy and congestive heart failure compared with healthy and asymptomatic hypertrophic cardiomyopathy groups.
Orbital inflammation with IgG4-positive plasma cells: manifestation of IgG4 systemic disease.

OBJECTIVE To describe clinical, radiographic, and morphologic findings in patients with IgG4-positive cells present on orbital biopsy specimens. DESIGN Retrospective review (from January 1, 1993, through December 31, 2006) of patients with orbital biopsy specimens that excluded lymphoma; comparison of patients with and without IgG4-positive cells on immunostaining. RESULTS Of 21 patients, 11 had increased IgG4-positive cells (defined as >10 cells on biopsy). Symptoms included eyelid or periocular swelling (8 patients) or proptosis (3 patients), with bilateral involvement in 6 patients. Computed tomographic imaging displayed lacrimal gland mass in 10 patients; 6 patients had lesions in other organs. Two patients had increased serum IgG4 levels. In 10 patients without IgG4-positive cells (≤10 cells on biopsy), 6 had proptosis, 1 had eyelid swelling, 2 had eyelid mass, and 1 had diplopia, all unilateral. None had systemic symptoms. Patients with IgG4-positive cells had longer symptom duration, and their biopsy specimens showed more background fibrosis, lymphoid hyperplasia, plasma cells, and eosinophils. CONCLUSIONS The clinical appearance, high incidence of bilateral disease, association with lesions in other organs, and increased IgG4 serum levels in some patients-with an increased number of IgG4-positive cells in the biopsy specimen, which shows more background fibrosis, lymphoid hyperplasia, plasma cells, and eosinophils-indicate that these patients have an orbital manifestation of IgG4-associated systemic disease.
Toward tailoring Majorana bound states in artificially constructed magnetic atom chains on elemental superconductors

We demonstrate the artificial construction of magnetic atom chains on a conventional superconductor as a Majorana platform. Realizing Majorana bound states (MBS) in condensed matter systems is a key challenge on the way toward topological quantum computing. As a promising platform, one-dimensional magnetic chains on conventional superconductors were theoretically predicted to host MBS at the chain ends. We demonstrate a novel approach to design of model-type atomic-scale systems for studying MBS using single-atom manipulation techniques. Our artificially constructed atomic Fe chains on a Re surface exhibit spin spiral states and a remarkable enhancement of the local density of states at zero energy being strongly localized at the chain ends. Moreover, the zero-energy modes at the chain ends are shown to emerge and become stabilized with increasing chain length. Tight-binding model calculations based on parameters obtained from ab initio calculations corroborate that the system resides in the topological phase. Our work opens new pathways to design MBS in atomic-scale hybrid structures as a basis for fault-tolerant topological quantum computing.
Examination Stress Results in Attentional Bias and Altered Neural Reactivity in Test-Anxious Individuals

Examination stress occurs so frequently in the lives of students. The neural mechanisms of attentional bias induced by examination stress in test-anxious individuals remain unclear. Accordingly, we investigated the attentional bias toward test-related threatening words in selected high and low test-anxious participants under the stress of final examinations by using an event-related potential (ERP) technique. A classic dot-probe paradigm was adopted with a test-related/test-unrelated threatening word and a neutral word pair as cues. Results showed attention bias and enhanced N200 amplitude toward test-related threat in high test-anxious individuals, whereas avoidance of test-related threat and decreased N200 amplitude were shown in low test-anxious individuals. Additionally, ERP data revealed the relatively enhanced LPP amplitude in low test-anxious participants compared with that in high test-anxious participants. No attentional bias toward test-unrelated threat was found. In conclusion, examination stress resulted in attentional bias and functional perturbations of a brain circuitry that reacted rapidly to test-related threat in high test-anxious individuals.
HUMAN CAPITAL PRODUCTIVITY, ENDOGENOUS GROWTH, AND WELFARE: THE ROLE OF UNCERTAINTY

Several policies or interventions have been implemented in developing countries with the ultimate goal of improving educational outcomes and human capital. Although many empirical studies have pointed to mixed results of these interventions, the role of uncertainty arising from the state of nature about the educational environment and household characteristics in the efficiency of these interventions still lacks an economic mechanism. This paper aims at developing a theoretical framework that links policy interventions to educational outcomes. We characterize optimal policies and determine the conditions for enhancing social welfare.
Application value of CT and MRI in diagnosis of primary brain lymphoma

This study explored the correlation between computed tomography (CT) and magnetic resonance imaging (MRI) manifestations and pathological features of primary brain lymphoma to improve the diagnostic accuracy. A total of 230 patients with primary brain lymphoma admitted to People's Hospital of Rizhao from July, 2005 to December, 2016 were selected into the study and their clinical data were analyzed retrospectively. Among them, 87 patients were examined by CT, 74 patients by MRI, 69 patients by both MRI and CT. Features of MRI and CT scanning figures were observed with a focus on the density, number and margins of the lesions, and the diagnostic accuracy was analyzed. A total of 353 lesions were identified from 230 primary brain lymphoma patients, of which 224 were single lesions, and 129 were multiple lesions. Most lesions were on the upper curtain (81.3%, 187 cases) and 43 cases (18.7%) were on the lower curtain. Lesion signal of CT and MRI plain scan showed uniform state, and enhanced scan showed significantly enhanced signal. Diagnostic accuracy of CT was 82.8%, and sensitivity and specificity was 75.5 and 67.4%, respectively. Diagnostic accuracy of MRI was 83.8%, and sensitivity and specificity was 79.3 and 64.9%, respectively. Diagnostic accuracy of MRI combined with CT was 89.9%, and sensitivity and specificity was 86.3 and 75.8%, respectively. CT combined with MRI can provide better diagnosis for primary brain lymphoma compared with CT or MRI alone, but pathological test is still needed.
Performance analysis of physical layer security over k - μ shadowed fading channels

In this study, the secrecy performance of the classic Wyner's wiretap model over k - μ shadowed fading channels is studied. More specifically, the authors derive two analytical expressions for the lower bound of secure outage probability at high signal-to-noise ratio regime and the probability of strictly positive secrecy capacity over k - μ shadowed fading channels, respectively. As there exist infinite series in the two derived expressions, they further obtain two simple and explicit approximate expressions for the lower bound of secure outage probability and the probability of strictly positive secrecy capacity with the aid of the moment matching method. It is shown that the match between the analytical results and simulations is very excellent for all parameters under considerations.
Multi-modality imaging features distinguish pancreatic carcinoma from mass-forming chronic pancreatitis of the pancreatic head

The present study retrospectively analyzed computerized tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography-computerized tomography (PET/CT) data to identify features that may distinguish pancreatic carcinoma (PC) from mass-forming chronic pancreatitis (MFCP) of the pancreatic head. The mean diameter of the lesions was larger in the MFCP patients (n=24) than in the PC patients (n=30; 5.44±27 vs. 3.34±1.23 cm; P<0.001). PC lesions showed increased lobulation when compared with the MFCP cases (83.33 vs. 12.5%; P<0.001). Lesions in the MFCP patients exhibited diffuse and marginally distributed calcification. MFCP patients showed increased exudation around the lesion (83.33 vs. 13.33%), pseudocyst formation (58.33 vs. 10%) and thickening of the right renal fascia (83.33 vs. 13.33%) than in the PC patients. MFCP patients also exhibited visible remnants of normal pancreatic tissue within the lesions. MFCP and PC patients could be distinguished by a cutoff value of 4.40 cm for lesion size [area under the curve (AUC): 0.894; 95% confidence interval (CI): 0.810–0.978)], 21.85 Hu for net-increased value in the arterial phase (AUC, 0.799; 95% CI, 0.670–0.928), 37.70 Hu for net-increased value in the portal phase (AUC, 0.798; 95% CI, 0.919–0.677), 4.85 for early standardized uptake value (SUV) of 18F-deoxyglucose (18F-FDG; AUC, 0.934; 95% CI, 0.850–1.018) and 4.90 for delayed SUV of 18F-FDG (AUC, 0.958; 95% CI, 0.878–1.038). These findings demonstrated that the integration of data from dynamic contrast-enhanced CT, MRI and PET/CT imaging may distinguish MFCP from PC.
Amplitude envelope correlations measure synchronous cortical oscillations in performing musicians

A major question facing cognitive neuroscience is measurement of interbrain synchrony between individuals performing joint actions. We describe the application of a novel method for measuring musicians’ interbrain synchrony: amplitude envelope correlations (AECs). Amplitude envelopes (AEs) reflect energy fluctuations in cortical oscillations over time; AE correlations measure the degree to which two envelope fluctuations are temporally correlated, such as cortical oscillations arising from two individuals performing a joint action. Wireless electroencephalography was recorded from two pianists performing a musical duet; an analysis pipeline is described for computing AEs of cortical oscillations at the duet performance frequency (number of tones produced per second) to test whether these oscillations reflect the temporal dynamics of partners’ performances. The pianists’ AE correlations were compared with correlations based on a distribution of AEs simulated from white noise signals using the same methods. The AE method was also applied to the temporal characteristics of the pianists’ performances, to show that the observed pair's AEs reflect the temporal dynamics of their performance. AE correlations offer a promising approach for assessing interbrain correspondences in cortical activity associated with performing joint tasks.
Factors within the family environment such as parents’ dietary habits and fruit and vegetable availability have the greatest influence on fruit and vegetable consumption by Polish children

Abstract Objective To identify determinants of fruit and vegetable (F&V) consumption among school-aged children. Design A survey study was conducted in October 2010. The questionnaire contained questions concerning social and demographic data, lifestyle and dietary habits, particularly the frequency of F&V consumption, availability of F&V and knowledge about recommended amounts of F&V intake. Setting Polish primary schools. Subjects Children (n 1255) aged 9 years from randomly selected primary schools and their parents. Results The children’s consumption of fruit and of vegetables was influenced by the fruit consumption and vegetable consumption of their parents (r=0·333 and r=0·273, respectively; P=0·001), parents encouraging their children to eat F&V (r=0·259 and r=0·271, respectively; P=0·001), giving children F&V to take to school (r=0·338 and r=0·321, respectively; P=0·001) and the availability of F&V at home (r=0·200 and r=0·296, respectively; P=0·001). Parental education influenced only the frequency of fruit consumption (r=0·074; P=0·01). A correlation between parents’ knowledge of the recommended intakes and the frequency of vegetable and fruit consumption by children was noticed (r=0·258 and r=0·192, respectively, P=0·001). Conclusions Factors within the family environment such as parents’ dietary habits and F&V availability had the greatest influence on the F&V consumption by children. Educational activities aimed at parents are crucial to increase the consumption of F&V among children.
End-of-life trends and patterns among children in the US foster care system: 2005–2015

Abstract Drawing on national, longitudinal Adoption and Foster Care Analysis, and Reporting System data (2005–2015), demographic, health, foster care, and geographic characteristics of decedents (N = 3653) aged 1–17 years were examined. On average, decedents were 6 years old, the highest proportion died as infants, and experienced significant trauma in their short lives either through maltreatment or exposure to parental substance use. A noted increase in Medicaid coverage among decedents over time suggests critical access to concurrent treatment and hospice care, but this is unavailable to children with private insurance. This study has policy implications related to the 2010 Affordable Care Act.