Miracle-dz/UniFAR-FTUs huggingface dataset:
Are Postoperative Complications Related to Resident Sleep Deprivation?

This real-world study compares the outcome of surgery and the sleep-deprivation status of the resident surgeon. Residents who operated the day after a 24-hour on-call period were considered sleep deprived; all other resident surgeons were considered non-sleep-deprived. We retrospectively reviewed data on 6,371 surgical cases and identified 351 postoperative complications. The complication data were analyzed using logistic regression analysis, with outcome being the presence or absence of surgical complications. No statistically significant change in complication incidence was noted when the resident surgeon was sleep deprived.
Streptococcal meningitis in pigs: results of a five-year survey

Information about new outbreaks of streptococcal meningitis in pigs has been collected since the disease was first recognised in the United Kingdom in late 1973. The apparent spread of the disease across the country is illustrated. Factors affecting the age distribution of the disease and the dissemination of the infection are also discussed.
Effective use of imatinib-mesylate in the treatment of relapsed chronic myeloid leukemia after allogeneic transplantation

Despite recent advances in the treatment of chronic myeloid leukemia (CML), allogeneic stem-cell transplantation (SCT) remains the only curative option. The success of SCT is limited because of relapse in 20–30% of patients. [1][1],[2][2] As the graft-versus-leukemia (GvL) effect contributes to
Adaptive threshold and sub-look processing in ship detection by SAR

The paper focuses on similarities and difference between adaptive threshold and sub-look processing in ship detection by Synthetic Aperture Radar (SAR). The main goal is to formalize the cascade application of both methods to achieve an overall reduction of the false alarm rate. The methods are tested on TerraSAR-X stripmap SAR data collected over the Gulf of Naples, Italy. Input parameters are set considering vessel traffic statistics in the area. Preliminary results confirm the capability of both the methods to attain very high detection rate (with zero missed detections in the considered case), and show that the synergic use of the methods reduces the number of false alarms, with respect to application of a single method.
Effects of aerobic exercise intensity on ambulatory blood pressure and vascular responses in resistant hypertension: a crossover trial

Background: Resistant hypertension often exposes patients to poor blood pressure (BP) control, resulting in clinical vulnerability, possible need for device-based procedures (denervation) and increased therapy costs. Regular exercise markedly benefits patients with hypertension, including resistant patients. However, little is known about short-term exercise effects in resistant hypertension. Objective: To evaluate acute hemodynamic effects of exercise in resistant hypertension. Method: After maximal exercise testing, 20 patients (54.0 ± 5.7 years, 30.2 ± 4.9 kg/m2) with resistant hypertension participated in three crossover interventions, in random order, and on separate days: control (45′ of rest), and light intensity and moderate intensity (45′ of aerobic exercise at 50 and 75% of maximum heart rate, respectively). Ambulatory BP, forearm blood flow (with subsequent calculation of vascular resistance), and reactive hyperemia were measured before and after interventions trough venous occlusion plethysmography. Results: Compared with control, both exercise intensities reduced ambulatory systolic pressure over 5 h (light: −7.7 ± 2.4 mmHg and moderate: −9.4 ± 2.8 mmHg, P < 0.01), whereas only light intensity reduced diastolic pressure (−5.7 ± 2.2 mmHg, P < 0.01). Light intensity also lowered systolic and diastolic pressures over 10-h daytime (−3.8 ± 1.3 and −4.0 ± 1.3 mmHg, respectively, P < 0.02), night-time (−6.0 ± 2.4 and −6.1 ± 1.6 mmHg, respectively, P < 0.05), and diastolic pressure over 19 h (−4.8 ± 1.2 mmHg, P < 0.01). Forearm blood flow changed (decreased) compared with baseline only at 50 min after light intensity (P < 0.05). After the control and light intensity sessions, vascular resistance increased at the end of 1 h, and after moderate intensity, it decreased only at the moment (∼2 min) immediately after intervention (P < 0.05). Conclusion: A single session of light or moderate aerobic exercise acutely reduces ambulatory BP in resistant hypertension, although benefits persist longer following light intensity.
Visual Acuity with the ITT Night Vision Aid for Patients With Night Blindness

ABSTRACT The Night Vision Aid is a photomultiplier device developed by International Telephone and Telegraph Co. (ITT) and the Retinitis Pigmentosa Foundation as a mobility aid for those with night blindness. The purpose of this study was to measure visual acuity with and without the Night Vision Aid at a variety of light levels to determine how much visual assistance it provided over a wide range of illuminations. Ten normal subjects and five patients with retinitis pigmentosa (RP) used the aid at nine luminance levels ranging from 10‐6 to 102 mL. With the device, visual acuity improved at light levels below 0.1 mL and target visibility was extended about 3 log units further into low luminance. At light levels above 0.1 mL, unassisted visual acuity was better in all normal and most RP subjects. The best visual acuity attained with the Night Vision Aid was 6/15 (20/50). Graphs and dark adaptation curves illustrate our findings.
The axillary versus internal mammary recipient vessel sites for breast reconstruction with diep flaps: A retrospective study of 256 consecutive cases

The aim of this study is to present our experience on the use of various recipient sites for deep inferior epigastric perforator (DIEP) flap breast reconstruction and compare them by means of objective data. Two hundred fifty six DIEP flap breast reconstructions, performed between March 2004 and May 2011, were retrospectively analyzed. Only unilateral reconstructions were included in the study and divided into three groups depending on the recipient site choice: internal mammary vessels (IMV) (n = 52), thoracodorsal vessels (TDV) (n = 109), and circumflex scapular vessels (CSV) (n = 95). Clinical records of each patient were reviewed to acquire relevant data such as operative time, postoperative complications, and use of a second vein anastomosis. CSV group showed a statistically significant lower operative time (4.92 ± 0.54 hours) compared to TDV (5.67 ± 1.01 hours) and IMV groups (6.75 ± 1.09 hours) (P < 0.001). Second vein anastomosis was performed in 84 cases (88.1%) of CSV, in 85 cases (77.9%) of TDV, and in 18 cases (35.1%) of IMV groups (P < 0.001). No significant differences were observed among groups regarding risk factors and complications (P > 0.05). The axillary vessels seem to be the ideal recipient site because of reduced operative time and increased possibility to perform a second vein anastomosis. Among them, CSV can be safely used due to following advantages: easy dissection, larger vessel caliber, and optimal flap insetting. Moreover, their location does not expose them completely to radiotherapy consequences. © 2014 Wiley Periodicals, Inc. Microsurgery 35:34–38, 2015.
Fuzzy-Network Planning - FNET

Currently used network planning techniques, such as PERT/CPM and their derivatives, assume that, in a graph of known structure, the duration of its activities is known either with certitude or at least with some probability. However, in many applications the structure of the graph and the duration of its activities are imprecise. This paper shows how the application of fuzzy sets to such problems can yield quasi-deterministic results obtained from imprecise Input data.
Hexamethylene bisacetamide leads to reduced helper virus‐free HSV‐1 amplicon expression titers via suppression of ICP0

The herpes simplex virus (HSV)‐derived amplicon vector has evolved into a promising gene transfer platform for widespread DNA delivery in gene replacement strategies and vaccine development given its ease of molecular manipulation, large transgene capacity, and transduction efficiencies of numerous cell types in vivo. The recent development of helper virus‐free packaging methodologies bodes well for this vector system in its eventual implementation as a clinically viable therapeutic modality. For realization of clinical application, efforts have been made to enhance yields and quality of helper‐free amplicon stocks. Hexamethylene bisacetamide (HMBA), a hybrid polar compound that exhibits stimulatory activity of HSV‐1 immediate‐early gene expression, has been employed as a standard reagent in helper virus‐free packaging given its purported mode of action on virus gene expression kinetics. Unexpectedly, we have found that HMBA exhibits no titer‐enhancing activity; in contrast, the compound enhances the proportion of amplicon virions that are non‐expressive. Omission of HMBA during vector packaging led to a marked reduction in the ratios of vector genome‐transducing to transgene‐expressing virions. This effect was neither packaging‐cell‐specific nor amplicon‐promoter‐dependent. Analysis of resultant vector stocks indicated amplicon genome replication/concatenation was unaffected, but the level of particle‐associated ICP0 was reduced in stocks packaged in the presence of HMBA. Inclusion of a co‐transfected, ICP0‐expressing plasmid into the packaging process led to significant rescue of amplicon expression titers, indicating that regulation of ICP0 concentrations is critical for maintenance of the amplicon genome expressive state. Copyright © 2007 John Wiley & Sons, Ltd.
Group A streptococci, mycoplasmas, and viruses associated with acute pharyngitis.

Methods for identification of bacteria, viruses, and mycoplasmas were used to study pharyngitis in patients from a pediatric practice. Etiologic agents were recovered from 50% of 715 cultures from patients with pharyngitis and from 22% of 206 cultures from asymptomatic household contracts. Pharyngitis was diagnosed most often in children ages 6 through 8 years, and over one half of these illnesses were associated with group A streptococcus infections. Viruses were the most important cause of pharyngitis in infants, and Mycoplasma pneumoniae was associated with pharyngitis in early adolescence. Disease produced by viruses or M pneumoniae could not be distinguished from classical streptococcal pharyngitis. Mycoplasma hominis, which has produced exudative pharyngitis in adult volunteers, was not recovered from persons in this investigation; however, in other studies performed concurrently, M hominis was isolated from 0.5% of subjects including three adults with pharyngitis.
Gastric Residual Volume Linked to Gastric Fluid pH in Infants with Very Low Birth Weight

Limited information exists regarding the correlation between gastric residual volume and gastric fluid pH before feedings in infants with very low birth weight. The purpose of this study was to evaluate this relationship in infants with feeding tolerance compared with that in those with feeding intolerance. A total of 86 infants with very low birth weight were included in the study, including 43 with feeding tolerance (study group) and 43 with feeding intolerance (control group). Gastric residual volume was obtained using a feeding tube and acidity measured using a pH-test paper. The gastric fluid pH was measured before each feeding in both the groups and compared. Demographic and clinical characteristics were similar between very low birth weight infants with and without feeding intolerance. Significant differences were observed in the gastric fluid pH between groups (p < 0.05). The gastric fluid pH value significantly increased with increasing gastric residual volume in a linear fashion (Pearson correlation = 0.543; P < 0.05). There is a positive linear correlation between gastric residual volume and gastric juice pH value in infants with very low birth weight.
PROTEIN SYNTHESIS IN NEURONAL PERIKARYA ISOLATED FROM CEREBRAL CORTEX OF THE IMMATURE RAT 1

Abstract— Homogenates of neuronal perikarya isolated from the cerebral cortex of the 8‐day‐old rat were incubated with [3H]leucine, and the characteristics of the protein synthetic process were studied. Incorporation of leucine into protein was linear up to 90 min, proceeded optimally at pH 7.6 and was stimulated by K+ and NH4+, unaffected by Li+ and inhibited by Na+. Puromycin, cycloheximide, RNAse, sulphhydryl blocking agents and phospholipase A exerted a pronounced inhibition, whereas chloramphenicol and phospholipase C had no effect. About 42 per cent of the total radioactive protein formed in the optimally fortified in uitro system was recovered in non‐sedimentable form. Incorporation into the subcellular fractions of the neuronal perikarya increased steadily with increasing time of incubation. The microsomal fraction acquired the highest specific radioactivity (d.p.m./mg of protein), followed by the mitochondrial and the nuclear + cell debris fractions. The high‐speed soluble fraction exhibited the lowest specific radioactivity.
Reproduction of Meloidogyne enterolobii in rootstocks and cucumber hybrids

This study aimed to determine the resistance of six rootstocks for cucumber (squash ‘Menina Brasileira’, pumpkin ‘Exposicao’, ‘Shelper’, ‘Tetsukabuto Takaiama’, ‘B8-A Tetsukabuto’ and ‘Excite Ikki’) and four Japanese cucumber hybrids (‘Yoshinari’, ‘Kouki’, ‘Taisho’ and ‘Tsuyataro’) to Meloidogyne enterolobii. The experiment was conducted in greenhouse; each plot consisted of one plant per pot containing 2 liters of autoclaved soil. The experimental design was completely randomized, with five replicates per treatment. Two days after transplanting the seedlings, each plant was inoculated with 5,000 eggs and second-stage juveniles (initial population = Pi) of M. enterolobii. Tomato ‘Rutgers’ was used as indicative of inoculum viability. Sixty days after inoculated, each plant was evaluated for total number of nematodes in the roots (final population = Pf) and reproduction factor (FR=Pf/Pi). All rootstocks and cucumber hybrids allowed M. enterolobii multiplication, but FR values were lower in ‘Shelper’, ‘Excite Ikki KY’ and ‘Menina Brasileira’ rootstocks. In a second experiment, the low FR in these three rootstocks was confirmed, but with higher values in ‘Menina Brasileira’. So, these rootstocks can be recommended to M. enterolobii infested areas, but with low populations, because they don’t permit great multiplication of the patogen. It is concluded that ‘Shelper’ and ‘Excite Ikki KY’ rootstocks had the lowest FR and can be classified as moderate resistant to this nematode.
Isolation of fungi for delignification of Pulp and Paper mill effluent

Biodegradation of industrial Lignin by a fungal isolate identified as Aspergillus flavus, white rot fungi which was isolated from Pulp and Paper effluent was studied in batch flask system with industrial effluent. The flasks were operated at temperature 32°C at 200 rpm for eight days in continuous mode. The average overall pH, Temperature, DO, C.O. D, T.D. S, T.S. S, Lignin, were up to 4.56, 32 o C, 4.2mg/l, 104mg/l, 6000 mg/l, 4000mg/l, 575.5mg/l, respectively after treatment. The Aspergillus flavus sp was the most effective in the biodegradation of Lignin of pulp industry for 94% at 480nm and of chemical oxygen demand levels for 45% after 8 days of incubation. The optimal conditions found were 4 pH and 32 o C temperature for lignin degradation
Synchrotron excitation, emission and theoretical simulation of lanthanide ions in hexachloroelpasolite crystals

Emission and excitation spectra of Cs2NaLnCl6 (Ln = Y, Eu, Gd, Er, Yb), Cs2NaYCl6:Ce and Cs2NaYCl6:Tm have been recorded using synchrotron radiation. With the possible exception of the case for Ce3+, no transitions are observed and the emission spectra are entirely assigned to intraconfigurational transitions of Ln3+ in LnCl63− and impurity species. The excitation spectra comprise intraconfigurational, charge transfer and band-to-band transitions. Trace impurities of oxy-species or of other lanthanide ions have a profound effect upon the spectra. The 4f–5d absorption spectra have been simulated by employing the suite of programs of Professor M F Reid and the results have been included together with the experimental spectra.
VARIATIONAL BOUNDARY VALUE PROBLEMS FOR QUASI-LINEAR ELLIPTIC EQUATIONS OF ARBITRARY ORDER.

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Finite-time control for networked switched linear systems with an event-driven communication approach

ABSTRACT This paper is concerned with the network-based finite-time controller design problems for a class of switched linear systems with sampled-data control approach, the quantisation errors are also taken into account. A novel event-driven communication scheme is developed which can be seen as the extension of time-driven communication cases. By invoking an input-delay approach, the networked switched control systems are firstly modelled as a kind of switched time-delay systems with time-varying delays, upon which a set of mode-dependent controllers are then designed such that the reformulated switched system with time-varying delays is finite-time bounded and has a guaranteed noise attenuation performance in the finite-time sense. Moreover, a co-design algorithm of mode-dependent control and event-driven communication is presented to find the optimal event-driven strategy for reducing transmission loads. Finally, a numerical example and an application to F-18 aircraft are provided to demonstrate the effectiveness and the advantages of the developed results.
Modeling and identification of centrifugal compressor dynamics with approximate realizations

This paper deals with the parameter identification of a model for the dynamic behavior of a large industrial centrifugal compression system. Experimental results are presented to evaluate a new approach for determining the parameters of a modified version of the well-known Greitzer model. This approach is based on an approximate realization algorithm that constructs an LTI model from step response data. It is shown that the method is capable of providing estimates for a limited set of model parameters. In a subsequent sensitivity analysis it is proven that the identifiable parameters are all related to the dominant dynamics of the system. The main conclusion is that the suggested approach is capable of providing estimates for the various model parameters. However, identification is limited to those parameters that are associated with dynamics that can be excited sufficiently during forced response experiments
On the occurrence of false positives in tests of migration under an isolation‐with‐migration model

The population genetic study of divergence is often carried out using a Bayesian genealogy sampler, like those implemented in ima2 and related programs, and these analyses frequently include a likelihood ratio test of the null hypothesis of no migration between populations. Cruickshank and Hahn (2014, Molecular Ecology, 23, 3133–3157) recently reported a high rate of false‐positive test results with ima2 for data simulated with small numbers of loci under models with no migration and recent splitting times. We confirm these findings and discover that they are caused by a failure of the assumptions underlying likelihood ratio tests that arises when using marginal likelihoods for a subset of model parameters. We also show that for small data sets, with little divergence between samples from two populations, an excellent fit can often be found by a model with a low migration rate and recent splitting time and a model with a high migration rate and a deep splitting time.
Ophthalmologic Follow-Up of Premature Twins and Triplets

Purpose To assess the influence of multiple gestation on the visual apparatus and on the general state of health of premature infants and to investigate the condition of the twin or triplet with the lowest birth weight compared to multiple gestation siblings. Methods Seventy-seven premature twins or triplets (8 to 54 months of age) were monitored at the Verona University Ophthalmology Department from November 1995 to November 1999. In another 12 subjects (younger than 8 months), only the neonatal disease records were examined; these subjects were excluded from the ophthalmologic follow-up because they were too young to be tested reliably. The study sample was compared with 120 premature singletons monitored from January 1996 to March 1998. Visual acuity, ocular motility, strabismus, refraction defects, dioptric media, and fundus oculi were assessed. Results The incidence of retinopathy of prematurity, refraction defects, or strabismus was not significantly different between premature twins or triplets and premature singletons. The twin or triplet with the lowest birth weight was more frequently affected by eye morbidity and the diseases typical of prematurity. This difference, however, was not statistically significant. Conclusions Premature infants are at a disadvantage compared to those born at term, irrespective of multiple birth status; multiple gestation adds no risk beyond that due to prematurity.
DIAGNOSTIC EXERCISE

An approximately one-and-a-half-year-old, neutered male, mixed-breed dog was presented for a chronic history of vomiting. Profuse diarrhea was also noted during examination. An exploratory laparotomy was performed, bone chips were removed from the stomach, and a raised, circular area of gastric mucosa was biopsied. Histologically, there was severe gastric cryptosporidiosis as well as numerous spiral bacteria, consistent with Helicobacter spp. Polymerase chain reaction revealed visible bands for the 18S ribosomal RNA gene for Cryptosporidium spp. The polymerase chain reaction product was sequenced and was found to be most similar to Cryptosporidium muris. Both the gastric location and the species of Cryptosporidium are unusual in a dog.
The histological and immunohistochemical evidence of squamous metaplasia from the myoepithelial cells in the breast

Squamous metaplasia in the breast is well documented. However, the putative cell of origin for the squamous epithelium is not clear. This paper describes a case of fibroadenoma of the breast with myoepithelial hyperplasia and squamous metaplasia. The histological finding of transition between myoepithelial cells and squamous cells and the immunohistochemical expressions of actin and S‐100 in the metaplastic squamous cells support the myoepithelial origin of squamous epithelium in the breast.