Miracle-dz/UniFAR-FTUs huggingface dataset:
Study the Effect of Different Aspects of Customer Relationship Management (CRM) on Innovation Capabilities with Mediator Role of Knowledge Management (Case Study: Mahram Company)

Research purpose: the purpose of this research is to study the effects of different aspects of customer relationship management (CRM) on innovation capabilities with mediator role of knowledge management variable. Five aspects of customer relationship management are sharing the information, participation with customer, long time cooperation, solving the problems jointly, technology-based customer relationship management and five aspects of innovation capabilities are product innovation, process innovation, administrative and marketing innovation and services, and also with regard to knowledge management role in collecting, keeping and dissemination of knowledge for managers as moderator or mediator variable has been included in the model and developed. Research methodology: for validation of suggested model, 140 questionnaires including 68 items were distributed among the personnel and staff of Mahram factory and also the managers and supervisors and all the retailers of Mahram products in all Iran branches and to investigate the research hypotheses, multiple Regression analysis was applied with using of spss software that direct and indirect effects of independent and mediator variables on dependent ones were measured and also model fitness was assessed by Lizerl software. Findings: with regard to rout analysis and total beta measurement for research variables, it was turned out all aspects of customer relationship management and knowledge management has a positive and meaningful effect on innovation kinds in Mahram Company. Practical implication: with regard to research findings, customers management knowledge which has been collected by customer relationship management tools is one of the most important sources of the company to achieve innovation capabilities and consequently competitive advantage over competitors that this important issue demands special regard of managers to develop the substructures of customer relationship management and knowledge management in the field of technologies so that through it information and knowledge of customers could be used in the best manner and relevant information could be given to them and through holding meetings and seminars and inviting the important and old customers and proposing common problems and cooperation with them, the customers ideas, opinions and designs about organizational innovation improvement, designing and developing new processes and better services and their opinions in products pricing could be used. DOI: 10.5901/mjss.2015. v6n6s6p343
Graft Detachment Rate in DSEK/DSAEK After Same-Day Complete Air Removal

Purpose: We retrospectively analyzed the rate of graft detachment from 310 Descemet stripping endothelial keratoplasty (DSEK)/Descemet stripping automated endothelial keratoplasty (DSAEK) cases performed by a single surgeon over a 10-year period using same-day complete air removal. Secondary outcome measures including primary graft failure, late endothelial graft failure, rejection events, and steroid-induced ocular hypertension were also analyzed. Methods: A retrospective chart review was performed on all patients receiving DSEK/DSAEK for any cause by the same surgeon at 2 separate institutions from January 2005 to December 2014. The air bubble used to promote graft–host apposition was completely removed after 1 hour. Descriptive statistical analysis was used to report the rates of graft detachment, and &khgr;2 analysis was used to assess for associations with secondary outcomes. Results: Among 310 endothelial keratoplasties analyzed, there were 19 graft detachments (6.1%). The graft detachment rate was higher during the learning curve, but rapidly declined with experience, and was 1.3% for the last 79 cases over a 4-year period. No primary graft failures were reported. The rate of steroid-induced ocular hypertension was 20%. The rate of graft failure was 8%. The rate of graft rejection events was 10.7%. Two of the 6 patients (33%) who underwent trabeculectomy before endothelial keratoplasty suffered a detachment. Conclusions: A graft detachment rate as low as 1.3% can be achieved in DSEK/DSAEK with same-day complete air removal shortly after surgery. Factors believed to contribute to a low detachment rate include complete interface fluid removal and reconstitution of the normal anterior chamber milieu to assist corneal endothelial function.
The Effectiveness of the Size Matters Handwriting Program

&NA; Date Presented 3/31/2017 With school‐based occupational therapists reporting up to 75% of their caseload related to handwriting, the urgency to identify a proven and efficient instructional program is paramount. Effective, embeddable, measurable, easy, and fast, the Size Matters Handwriting Program promotes collaboration in the natural environment and the Workload model. Primary Author and Speaker: Beverly Moskowitz Additional Authors and Speakers: Beth Carswell, Jennifer Kitzmiller, Moira Bushell, Laura Neikrug, Chaya Gottesman Contributing Authors: Beth Pfeiffer, Gillian Rai, Tammy Murray
Optimal strategies for selling wind power in mid-term energy auctions

Due to the environmental pollution and the emission of CO2 of conventional fossil-fueled power plants, renewable energy sources are becoming an important part of the generation mix in many electricity markets. For example, in the Spanish market, during the day March 27th 2008, wind power covered the 24% of the daily demand. This is a consequence of the active role that wind producers have taken in the Spanish system by participating both in the day-ahead spot market and in the base-load energy auctions organized to cover a percentage of the demand of the distribution companies. This panel-session paper presents the basic ideas of a more detailed paper under development, and its main objective is to find the optimal strategy of a wind producer to sells its energy in mid-term demand procurement auctions subject to price and production uncertainty.
Utility of the School Motivation Analysis Test in predicting second language acquisition

The School Motivation Analysis Test (SMAT) is a 190-item, objective (T-data), multidimensional instrument for measuring factor analytically derived adolescent motivation dimensions. The SMAT was administered to 109 high school students (63 females, 46 males) enrolled in a Melbourne metropolitan foreign language school. Sten scores on the SMAT dynamic source traits (Assertiveness, Mating/Sex, Fear/Escape, Narcism, Pugnacity, Protectiveness, Self-sentiment, Superego, School Orientation, and Home Orientation) were used to predict achievement (combined across Comprehension, Grammar, Written Expression, and Oral Expression) via separate stepwise forward multiple regression analyses for each of five subgroups of SMAT variables (Integrated, Unintegrated, Total, Conflict, and Derivative components, respectively). SMAT dynamics accounted for up to 34 per cent of the achievement variance (males) and 26 per cent (females). Integrated Superego and Assertiveness sentiments were significant predictors of learning. However, only for the Total (U + I) stens, was Self-sentiment a significant predictor. The derivative stens accounted for 15 per cent of the achievement variance (males), and 12 per cent (females). Results also showed that gender was a major determinant of achievement outcomes, with males and females exhibiting different patterns of motivational investment in second-language acquisition.
Journal of Complementary and Integrative Medicine Glucosinolates : The Phytochemicals of Nutraceutical Importance

Glucosinolates (thioglucoside-N-hydroxysulphates) constitute a homogeneous class of naturally occurring thiosaccharidic compounds mainly found in the botanical order Brassicales. They can be hydrolyzed by myrosinase to produce D-glucose and various other degradation products like isothiocyanates (ITCs)-depending on the aglycon part. The exact function of glucosinolates (GLSs) in the plant is unclear, however their potent odour and taste suggests a role in herbivore and microbial defense. They are known for their fungicidal, bacteriocidal, nematocidal and allelopathic properties and have recently attracted intense research interest because of their cancer chemo-protective attributes. Iso-thiocyanates, one of the hydrolyzed products, show best anti-carcinogenic activity.
Update on Cavitation Cavitation and Its Discontents : Opportunities for Resolving Current Controversies 1 [ C ]

Cavitation has long been recognized as a key constraint on the structure and functional integrity of the xylem. Yet, recent results call into question how well we understand cavitation in plants. Here, we consider embolism formation in angiosperms at two scales. The first focuses on how air-seeding occurs at the level of pit membranes, raising the question of whether capillary failure is an appropriate physical model. The second addresses methodological uncertainties that affect our ability to infer the formation of embolism and its reversal in plant stems. Overall, our goal is to open up fresh perspectives on the structure-function relationships of xylem.
Lung Transplantation for Pulmonary Langerhans' Cell Histiocytosis: A Multicenter Analysis

Background. Lung transplantation (LT) may represent a therapeutic option in case of advanced pulmonary Langerhans' cell histiocytosis (PLCH). Little is known however about the characteristics of the patients considered for LT or its results. Methods. We conducted a retrospective multicenter study by questionnaire on 39 patients who underwent LT for end-stage PLCH at seven centers in France. Results. Of the 39 patients, 15 received single lung transplantation, 15 double lung transplantation and 9 heart-lung transplantation. At evaluation, extrapulmonary involvement was present in 31% of the patients, pulmonary hypertension (PAPm>25 mm Hg) was observed in 92% of cases and was moderate-to-severe (PAPm≥35 mm Hg) in 72.5%. The survival was 76.9% at 1 year, 63.6% at 2 years, 57.2% at 5 years, and 53.7% at 10 years. Recurrence of the disease occurred in eight cases (20.5%) with no impact on the survival rate. The sole risk factor for recurrence of the disease was the presence of preoperative extrapulmonary involvement. Conclusion. Severe pulmonary hypertension is a common feature in patients with end-stage PLCH. Given the good postransplant survival rate and despite a recurrence rate of the disease of approximately 20% after LT, we conclude that LT is a therapeutic option in this setting.
Lambda responses in the human electroencephalogram

SINCE LAMBDA WAVES were first reported by Evans1 in 1953, several studies, particularly those of GreenZ and of Gastaut and Bert,3 have added further information on the lambda mechanism. However, the present study contains a more detailed examination of the stimulus parameters of the lambda response than has been reported previously. In addition, the quantitation of lambda waves is undertaken mainly by direct measurement, although a brief reference to summation techniques will be made. In particular, the form, size, brightness, color, and movement of the visual stimulus necessary for the production of lambda waves has been examined. The relations between eye movement and the lambda wave as well as the similarity of the photic and the lambda responses were studied. Finally, the effects of certain psychologic variables, for example, fatigue, mental activity, and the hypnotic state, have been investigated.
Approximate Newton Methods and Their Local Convergence

Many machine learning models are reformulated as optimization problems. Thus, it is important to solve a large-scale optimization problem in big data applications. Recently, stochastic second order methods have emerged to attract much attention for optimization due to their efficiency at each iteration, rectified a weakness in the ordinary Newton method of suffering a high cost in each iteration while commanding a high convergence rate. However, the convergence properties of these methods are still not well understood. There are also several important gaps between the current convergence theory and the performance in real applications. In this paper, we aim to fill these gaps. We propose a unifying framework to analyze local convergence properties of second order methods. Based on this framework, our theoretical analysis matches the performance in real applications.
Political economy of marine reserves: Understanding the role of opportunity costs

The creation of marine reserves is often controversial. For decisionmakers, trying to find compromises, an understanding of the timing, magnitude, and incidence of the costs of a reserve is critical. Understanding the costs, in turn, requires consideration of not just the direct financial costs but also the opportunity costs associated with reserves. We use a discrete choice model of commercial fishermen’s behavior to examine both the short-run and long-run opportunity costs of marine reserves. Our results can help policymakers recognize the factors influencing commercial fishermen’s responses to reserve proposals. More generally, we highlight the potential drivers behind the political economy of marine reserves.
Reduced folate carrier polymorphism determines methotrexate uptake by B cells and CD4+ T cells.

OBJECTIVE To examine if polymorphism 80G --> A in the Reduced Folate Carrier (RFC) affects uptake of MTX in B- and CD4+ T-cells. METHODS Mononuclear cells were isolated from peripheral blood of healthy persons. Real-time PCR was used to detect the RFC80 variants. FITC-labelled MTX was added to cells stimulated with Candida albicans or tetanus toxoid, and the uptake of MTX was measured by flow cytometry. A FITC-conjugated monoclonal antibody against RFC was used to detect the cellular RFC expression. RESULTS Antigen-stimulated CD4+ T cells and B cells from individuals with the GG variant (n = 9) exhibited lower uptake of MTX than individuals expressing the AA variant (n = 8), or the GA variant (n = 8). No difference could be demonstrated between the three groups with respect to the expression of RFC by CD4+ T cells and B cells, and CD4+ T cells from individuals homozygous for the G allele exhibited lower uptake of MTX per receptor than CD4+ T cells from individuals homozygous for the A allele. CONCLUSION MTX is taken up more efficiently via the A allele than via the G allele. This difference between the variant forms of RFC suggests that genotyping could be relevant for determining the relevant dosage of MTX in the treatment of neoplastic and autoimmune disease.
The origin of the Indo-Iranians

Here then is the fruit of Elena Kuz'mina's life-long quest for the Indo-Iranians. Already its predecessor (Otkuda prishli indoarii? , published in 1994) was considered the most comprehensive analysis of the origins of the Indo-Iranians ever published, but in this new, significantly expanded edition (edited by J.P. Mallory) we find an encyclopaedic account of the Andronovo culture of Eurasia. Taking its evidence from archaeology, linguistics, ethnology, mythology, and physical anthropology pertaining to Indo-Iranian origins and expansions, it comprehensively covers the relationships of this culture with neighboring areas and cultures, and its role in the foundation of the Indo-Iranian peoples.
Time-series cross-sectional environmental performance and disclosure relationship: specific evidence from a less-developed country

This paper relies on ‘vulnerability and exploitability’ framework to submit new insights into legitimacy theory and voluntary disclosure theory using specific empirical evidence from the Nigerian oil and gas industry. The study connects the voluntary and legitimizing disclosure behaviors, regarding carbon emission due to gas flaring, of dominant companies in the Nigerian upstream petroleum sector to the vulnerability and exploitability of Nigeria as a less developed country. The hypothesized relations between gas flaring-related environmental performance and two forms of its disclosure (volume and substance) are estimated and tested using Prais-Winsten regression with Panel Corrected Standard Errors (PCSE). While the paper uses Data Envelopment Analysis (DEA) to measure gas flaring-related carbon performance, the two forms of gas flaring-related disclosures are measured using content analysis. We document significant positive and negative association between gas flaring-related carbon emission performance, on one hand, and the volumetric disclosure and disclosure substance on the other hand. These results imply that while the positive relation confirms the vulnerable nature of Nigeria as a less developed country, the negative relation is linked to the country’s exploitability. It is also empirically established that environmental performance is one of the key factors responsible for the undulating trend in the volume of environmental disclosures by large corporations operating in less-developed countries
Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio in Fibromyalgia

Objective:We aimed at contributing to the understanding of the pathophysiology of Fibromyalgia (FM) by measuring neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR), which are the systemic inflammatory response (SIR) markers in patients with fibromyalgia.Method:The study population consisted of 70 patients newly diagnosed with FM (mean (SD) age: 43.9 (±9.8) years, 80% were female) and 52 healthy volunteers (mean (SD) age: 43.4 (±10.4) years, 76.9% were female). American College of Rheumatology-ACR 1990 criteria regarding the evaluation of widespread pain and tender points were used for the diagnosis of FM. Demographic characteristics, anthropometrics and laboratory findings were used to make comparisons between patient and control groups.Results:PLR was 128.0 (±40.2) in the patient group while it was 110.5 (±33.6) in the control group and the difference was found to be significant (p=0.03). NLR was similar in both groups. The tender point count was significantly higher in the patient group (p<0.001) whereas there was a negative correlation between the tender point count and the lymphocyte count (r= -0.200; p=0.020) and a strong positive correlation with PLR (r=0.022; p=0.001). Conclusion:Our findings indicate that NLR levels were similar in both groups while the PLR values of the FM patients were found to be significantly higher than those of the control group and there was a positive correlation between PLR and the tender point count.
A COMPLETE SPECTROSCOPIC SURVEY OF THE MILKY WAY SATELLITE SEGUE 1: THE DARKEST GALAXY

We present the results of a comprehensive Keck/DEIMOS spectroscopic survey of the ultra-faint Milky Way satellite galaxy Segue 1. We have obtained velocity measurements for 98.2% of the stars within 67 pc (10′, or 2.3 half-light radii) of the center of Segue 1 that have colors and magnitudes consistent with membership, down to a magnitude limit of r = 21.7. Based on photometric, kinematic, and metallicity information, we identify 71 stars as probable Segue 1 members, including some as far out as 87 pc. After correcting for the influence of binary stars using repeated velocity measurements, we determine a velocity dispersion of 3.7+1.4 − 1.1 km s−1. The mass within the half-light radius is 5.8+8.2 − 3.1 × 105 M☉. The stellar kinematics of Segue 1 require very high mass-to-light ratios unless the system is far from dynamical equilibrium, even if the period distribution of unresolved binary stars is skewed toward implausibly short periods. With a total luminosity less than that of a single bright red giant and a V-band mass-to-light ratio of 3400 M☉/L☉, Segue 1 is the darkest galaxy currently known. We critically re-examine recent claims that Segue 1 is a tidally disrupting star cluster and that kinematic samples are contaminated by the Sagittarius stream. The extremely low metallicities ([Fe/H] < −3) of two Segue 1 stars and the large metallicity spread among the members demonstrate conclusively that Segue 1 is a dwarf galaxy, and we find no evidence in favor of tidal effects. We also show that contamination by the Sagittarius stream has been overestimated. Segue 1 has the highest estimated dark matter density of any known galaxy and will therefore be a prime testing ground for dark matter physics and galaxy formation on small scales.
Satellite communications link adaptation design and interaction with TCP

The dynamic allocation algorithm is designed where each link's traffic is reported as the number of IP packets in a variety of queues. There can be a number of queues corresponding to differentiated traffic, but there is no mechanism for determining if more than a single TCP flow is generating the traffic within a single differentiated queue. The interaction between dynamic allocation algorithms and TCP is investigated and illustrated in this paper. The goal is to help dynamic link adaptation designer's select system parameters that are compatible with TCP and geosynchronous satellite links. In general, quickly varying the link data rate over a wide range of values does not maximize system throughput. However, dynamic link adaptation leads to greater throughput than static robust links if bursts of higher data rate are granted when the channel can support such an increase. In addition, the results in this paper show that the manner in which the dynamic allocation algorithm transitions between states affect the system performance.
Systematic, multiparametric analysis of Mycobacterium tuberculosis intracellular infection offers insight into coordinated virulence

A key to the pathogenic success of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, is the capacity to survive within host macrophages. Although several factors required for this survival have been identified, a comprehensive knowledge of such factors and how they work together to manipulate the host environment to benefit bacterial survival are not well understood. To systematically identify Mtb factors required for intracellular growth, we screened an arrayed, non-redundant Mtb transposon mutant library by high-content imaging to characterize the mutant-macrophage interaction. Based on a combination of imaging features, we identified mutants impaired for intracellular survival. We then characterized the phenotype of infection with each mutant by profiling the induced macrophage cytokine response. Taking a systems-level approach to understanding the biology of identified mutants, we performed a multiparametric analysis combining pathogen and host phenotypes to predict functional relationships between mutants based on clustering. Strikingly, mutants defective in two well-known virulence factors, the ESX-1 protein secretion system and the virulence lipid phthiocerol dimycocerosate (PDIM), clustered together. Building upon the shared phenotype of loss of the macrophage type I interferon (IFN) response to infection, we found that PDIM production and export are required for coordinated secretion of ESX-1-substrates, for phagosomal permeabilization, and for downstream induction of the type I IFN response. Multiparametric clustering also identified two novel genes that are required for PDIM production and induction of the type I IFN response. Thus, multiparametric analysis combining host and pathogen infection phenotypes can be used to identify novel functional relationships between genes that play a role in infection.