Miracle-dz/UniFAR-FTUs huggingface dataset:
COMPARAÇÃO DA QUALIDADE DE VIDA NOS DIFERENTES TIPOS DE INCONTINÊNCIA URINÁRIA FEMININA

OBJETIVOS: Comparar o impacto do tipo de incontinencia urinaria sobre a qualidade de vida em mulheres. METODOS: Foram avaliados retrospectivamente 77 prontuarios de mulheres incontinentes que realizaram tratamento fisioterapeutico entre fevereiro de 2005 a outubro de 2006. De acordo com os dados do exame urodinâmico, as mulheres foram classificadas em tres grupos: incontinencia urinaria de esforco (IUE), hiperatividade vesical (HV) e incontinencia urinaria mista (IUM). As voluntarias responderam a uma anamnese com dados demograficos e ao King's Health Questionnaire, questionario especifico para avaliacao da qualidade de vida em individuos com incontinencia urinaria. RESULTADOS: A maioria das pacientes (44%) apresentou IUM. A idade das pacientes acometidas por HV foi significativamente maior se comparada a idade das pacientes dos demais grupos. As mulheres acometidas por IUM apresentaram um impacto negativo significativamente maior sobre a qualidade de vida (dominio percepcao geral da saude) e sobre a percepcao de que a incontinencia afeta de modo negativo a propria vida em comparacao com as pacientes dos demais grupos. CONCLUSAO: Este estudo indicou que pacientes com IUM apresentaram um maior impacto negativo sobre a qualidade de vida.
Evaluation of body condition in pregnant rabbit does by ultrasound scanner

Riassunto Stima dello stato di ingrassamento di coniglie gravide tramite ecografo – Scopo del lavoro è stato studiare le variazioni delle condizioni corporee di coniglie sottoposte a due diversi ritmi riproduttivi (fisso - IA 11 d dal parto; alternato - IA 1 e 27 d dal parto) e valutare l’efficacia di un ecografo per la stima in vivo delle loro riserve adipose (retroscapolari, perirenali e totali). Il ritmo riproduttivo fisso ha determinato la presenza di un ridotto deposito di grasso in entrambi i siti. La misurazione con l’ecografo sembra essere accurata e discriminare lo stato delle riserve adipose, ma in presenza di spessori di grasso esigui la capacità di previsione dell’apparecchio scende drasticamente.
Prevalence and intensity of geohelminths infection in Oba-Ile Community of Osun State, Nigeria

This study has determined the prevalence and intensity of geohelminth infections and the effect of some epidemiological factors on their distribution in Oba Ile, Osun State, Nigeria. The study was conducted between November 2004 and March 2005. Of 489 school children examined, 76.9% harboured Ascaris lumbricoides while 54.6% and 29.2% had hookworm and Trichuris trichiura respectively. The prevalence and intensity of all the three species of geohelminths significantly (p A. lumbricoides and hookworm was the commonest (58.6%) multiple infection. Statistical analysis showed that walking barefoot was the only risk factor for hookworm infection at regular (OR 4.39, 95%CL 2.59-7.45, p A. lumbricoides and T. trichiura infections. Geophagous pupils were at significantly increased risk of having the three species of geohelminths at both regular and occasional levels. Keywords : geohelminths, prevalence, intensity, infection determinants. Nigerian Journal of Parasitology Vol. 27 2006: pp.62-67
Pharmacotherapy of gestational trophoblastic neoplasia

Introduction: Gestational trophoblastic neoplasia (GTN) is an encompassing term for the malignant forms of gestational trophoblastic disease that require treatment with chemotherapy due to their propensity to both locally and systemically invade, and compromise survival if untreated. GTN is inherently chemotherapy sensitive with excellent cure rates; however, resistant/relapsed high-risk disease, liver/CNS metastases and placental site trophoblastic tumor can be challenging to treat. Due to rarity of the condition, there is lack of randomized trial data leading to variation in practice. Areas covered: This review covers the primary and relapse/resistant pharmacotherapy of both low- and high-risk GTN, with consideration of liver, CNS metastases and placental site trophoblastic tumor. The Pubmed and Cochrane databases have been searched with keywords – gestational trophoblastic neoplasia, gestational trophoblastic disease, low-risk GTN, high-risk GTN, relapsed GTN and placental site trophoblastic tumor. Expert opinion: Consensus is required amongst the specialist centers in defining the risk groups; hence, minimizing treatments in the low-risk group, identifying those patients at risk of relapse and tailoring treatments appropriately. While experts strive for randomized-controlled trials, international collaboration needs to continue to gather further insight into these rare diseases.
Introducing Prioritisation Protocols to Promote Efficient and Effective Allocation of Mental Health Occupational Therapy Resources

At a time of unprecedented financial constraints in the National Health Service, occupational therapy services are required to develop mechanisms to ensure the efficient allocation of occupational therapy resources. This paper describes the development of prioritisation protocols within a mental health trust. A review of their implementation found that occupational therapists were finding the protocols helpful in prioritising referrals and clarifying the added value of their interventions. These findings and the follow-up action plan suggest how protocols such as these can be used effectively to ensure that the occupational needs of service users are met, resulting in enhanced outcomes.
Antiepileptic drugs as human teratogens

Background: There is still uncertainty concerning the risk of fetal malformation associated with the intake of various individual antiepileptic drugs in pregnant women. Objective: To assess the better-quality available evidence concerning the fetal hazards from exposure to antiepileptic drug monotherapy during human pregnancy. Method: Examination of the available English language literature, particularly that dealing with individual antiepileptic drugs used in monotherapy, in the larger case series with better-quality internal comparison data. Conclusions: There is reasonable evidence that valproate is a significant teratogen during therapeutic use in women; the other older antiepileptic drugs (phenobarbitone, phenytoin, carbamazepine) probably have some teratogenic potential, but less than valproate; the situation regarding the more recently marketed antiepileptic drugs is not yet clear.
Nutritional Status of Newly Enrolled Primary School Children in Jos-Plateau, Nigeria

3 Abstract: Nutritional assessment of newly enrolled school children is needful to identify children with poor nutritional status. Poor nutrition as evidenced by poor growth and small stature could affect development, intellectual performance and intellectual achievement. Poor nutrition in school aged children is also likely to negatively affect their participation in normal school activities. Seven hundred and sixty four apparently healthy newly enrolled pupils were randomly selected using a multi stage proportionate sampling from both public and private schools. Their weights and heights were measured using standard methods. Undernutrition was determined using Z scores less than - 2 standard deviations of the NCHS/WHO international reference standard. Pupils from private schools were significantly taller (118.2±6.52) than their public school counterparts (115.7±8.44), p = 001. The prevalence of underweight, stunting and wasting was 10.3, 11.1 and 2.4% respectively. Stunting occurred in a higher proportion of boys than girls. Poor nutritional status was significantly commoner in public school pupils compared with private school pupils. These findings suggest that malnutrition (underweight, wasting and stunting) is not uncommon among newly enrolled school children and it underscores the need for institution and sustenance of a food program among school children.
Monitoring of Volatile Anesthetics in Operating Room Personnel Using GC-MS

Objective: To estimate individual occupational exposure of operating room personnel to nitrous oxide, sevoflurane, isoflurane and halothane during regular working hours. Methods: Volatile anesthetics in urine and breathing area air samples were measured in forty subjects. Passive samplers were collected after continuous five-to-seven hours of exposure. Further, thirty air samples, using passive samplers, were collected from 14 operating rooms of the Jordan University Hospital. All air and urine samples were analyzed using static headspace sampler coupled to capillary column GC-MS system. Results: The monitored anesthetic volatile agents values of breathing area air samples were as the following (mean  SEM, ppm): 43.2  6.29, 4.16  2.38, 0.19  0.05 And 0.15  0.10 for nitrous oxide, sevoflurane, isoflurane and halothane, respectively. Whereas, values of the post- shift urine samples (mean  SEM, μg/l) were: 1234  209, 4.3  0.82, 3.75  0.7 and 9.9  1.2 for nitrous oxide, sevoflurane, isoflurane and halothane, respectively. Concerning operating rooms contaminations, the median and the (range) values for N2O were 90.4 ppm (12.2 – 327), for sevoflurane they were 16.4 ppm (2.14-53.7), for isoflurane 10.7 ppm (0.41-24.9) and for halothane 0.71 ppm (0.00 8-6.05). Conclusions: Based on the results of this study, it is obvious that operating rooms personnel were exposed to high level of anesthetic agents and therefore, it is recommended to install efficient scavenging systems inside the operating rooms beside the regular maintenance of anesthetic machines. Moreover, the awareness of operating room personnel should be increased in order to minimize possible health risk. Abbreviations: MS= Mass Spectrometry; GC= Gas liquid Chromatography; NIOSH= United States Institute for Occupational Safety and Health; JUH: Jordan University Hospital; MeOH= Methanol; ug= microgram; v/v= Volume to volume; SIM; Single Ion Monitoring; ppm= one part per million parts; TWA= Time Weighted Average: r2 =Correlation coefficient: SEM= Standard Error of the Mean
Aids em área rural de Minas Gerais: abordagem cultural

OBJETIVO: Descrever comportamentos facilitadores a exposicao ao HIV/Aids em populacao rural. METODOS: Pesquisa qualitativa realizada com 52 pacientes atendidos em ambulatorio de DST/Aids, em 2002-2003. Foram feitas entrevistas abertas e semi-estruturadas em profundidade com os participantes (30 homens e 22 mulheres), conduzidas no ambulatorio ou em suas residencias, em municipios rurais da regiao norte de Minas Gerais. As entrevistas foram transcritas, analisadas em categorias: concepcoes da doenca, trabalho, sociabilidade, informacoes previas sobre a doenca, modo de vida. A interpretacao dos resultados baseou-se na analise de conteudo. RESULTADOS: Na percepcao dos entrevistados, a Aids era "doenca de cidade grande" e de "forasteiro", desvinculada da cultura local. Todos os entrevistados se infectaram atraves de atividades heterossexuais ou homossexuais. A migracao rural-urbana e aspecto relevante da infeccao do HIV na regiao devido ao deslocamento em busca de trabalho. CONCLUSOES: As nocoes populares de doenca contribuem para vulnerabilidade a infeccao pelo HIV. E necessario apreender nocoes culturais locais para melhor entender as categorias de pensamento dessa populacao, enfocando essas nocoes ao divulgar informacoes sobre a doenca.
Development and characterization of murine monoclonal antibody specific for the P1.4 PorA proteins from strain B:4:P1.(7b).4. of Neisseria meningitidis

Neisseria meningitidis isolates are conventionally classified by serosubtyping that characterizes the reactivities of the PorA outer membrane protein variable-region epitopes with monoclonal antibodies. Porins are outer membrane proteins (OMPs) of N. meningitidis serogroup B and have attracted study principally for two reasons: their use in the classification of meningococcal isolates into serotype and subtype and as potential components of vaccines against this important pathogen. New murine hybridomas, secreting specific monoclonal antibodies against PorA serotype P1.4 of N. meningitidis serogroup B, were generated using conventional hybridoma procedures. The monoclonal antibodies obtained were characterized by Western blot and whole cell ELISA, using reference strains from different N. meningitidis serotypes and subtypes. All monoclonal antibodies belong to isotype IgG1. Others hybridomas producing MAbs against PorB and FrpB were also obtained.
Percepción de la calidad de la atención de los servicios de salud en México: perspectiva de los usuarios

Objective. To describe the quality of health services as perceived by users in Mexico, as well as an analysis of predisposing and enabling factors to the use of these services. Materials and methods. Data were selected from the National Health Survey II of 1994. The survey contains information from 3324 ambulatory health service users who sought care in the two week period previous to the survey. Results. 81.2% of users perceived the quality as good and 18.8% thought it was poor. The main reasons for good quality of care were: personal attention (23.3%) improvement of the health problem (11.9%). For poor quality of care, the main reasons were: long waiting time (23.7%) and poor clinical examination (11.7%) Social security health service users perceived 2.6 times more frequently quality of attention as poor, than those who consulted private health services. Quality is represented by the aspects of the attention process (44.8%9, its results (21.3%), the structure (18.0%) and accessibility (15.7%) The main reasons for not returning to the same health service center were: deficient attention (18.2%) and long waiting times (11.8%). Conclusions. The perspective of the population should be studied further and actions for the continuous improvement of the quality of health care should be implemented.
Risk Assessment of Physical Health Hazards in Al-Azhar University Hospital in New Damietta, Egypt

Introduction: Personnel working in hospitals are exposed to many occupational hazards that may threaten their health and safety. Physical hazards that are encountered in hospital working environment include temperature, illumination, noise, electrical injuries, and radiation. Objectives: The objectives of this study were to identify physical health hazards in all departments of Al-Azhar University Hospital in new Damietta, to measure risk level of these hazards, and to recognize safety measures in these departments. Study Site: The study was conducted in Al-Azhar University Hospital in Damietta Governorate. Study Subjects: All personnel (328) working in the hospital were recruited. Study Methods: Interview forms; a workplace inspection checklist, assess physical health hazards in the hospital and a modified checklist (workplace safety and health risk management, assess leadership commitment towards workplace safety and health). Risk assessment matrix was used to describe the risk level. Also, environmental measurements of noise, temperature, relative humidity, and lighting were taken in all departments including auxiliary service offices. Results: Majority of the staffs reported stairways were free of obstacles, emergency lighting worked properly, and temperature was suitable. Minority of the staffs reported stairways were slippery, they were informed on hazards of noise and non-ionizing radiation, and they were given radiation safety training. Measurements of physical agents revealed noise levels were above standard of the WHO in all wards and above slandered of OSHA as in laundry, kitchen, etc. Range of noise level was from 58 dB in renal dialysis unit to 88 dB in kitchen. Lighting level was from 290 to 1150 Lux, temperature level was from 25 to 31°C, relative humidity level was from 45 to 59%, and heat index was low in all departments except kitchen and boiler room, it was moderate. Risk level of electrical and fire hazards was medium 22 (B), while other hazards were of low risk level; 01, 11, and 12 (A). Leadership commitment towards safety and health in the hospital was only 14.3%. Recommendations: Workplace environment should be monitored and evaluated. Environmental and behavioral interventions are indicated for all personnel to prevent undue exposures. Noise monitoring and noise engineering and administrative control should be established. Increase leadership commitment towards workplace safety and health. Training programs on health and safety issues should be conducted to all healthcare workers. Lastly, further studies in different hospitals in Egypt are needed to investigate this health problem.
Influence of Socioeconomic Status on the Association between Prenatal Periodontal Care and Preterm Low Birthweight Delivery: A Population-Based Case-Control Study

We report the effect of in-pregnancy periodontal care intensity on the risk of preterm low birthweight (PLBW) births, and the role of household income in this association. Only a few studies have examined the role of socioeconomic status (SES) in the relationship between prenatal periodontal care and risk of PLBW delivery under universal health care. This study adopted a population-based, case-control study using medical claims data in Taiwan. Mothers of PLBW and non-PLBW babies with livebirth deliveries between 2001 and 2005 (cases, n=20430 and controls, n=81573, respectively) were identified using the National Health Insurance Research Database (NHIRD) and matched. Periodontal disease and disease-specific (gingivitis and periodontitis) dental service utilization was calculated during gestational period and analyzed for its association with risk for PLBW delivery. Household income as proxy for SES was tested for modification effect. Prevalence of periodontitis and gingivitis was significantly higher
Predictions of mortality from mesothelioma

Sorahan and Nichols,1 writing in this journal, incorrectly understate the strength of evidence for work related increased mortality among their cohort of production workers in the UK flexible polyurethane foam industry. Their study actually found “some” evidence for a work related increase in all-cause mortality, respiratory disease mortality, and lung cancer mortality in this exposure circumstance, especially taking into account the healthy worker effect.2 We are concerned to correct this error, because the United Automobile, Aerospace and Agricultural Implement Workers of America (UAW) represents substantial numbers of workers exposed to this process, and the UK data provide the first evidence of a mortality hazard in this industry, in contrast to two previous, perhaps weaker studies.3,4 The authors observed an all-cause standardised mortality ratio (SMR) among men of 107 (101 to 113), and a respiratory disease SMR of 120 (101 to 141). Increased mortality of similar magnitude from these causes was observed among the smaller number of women, and the SMRs for both genders combined were significantly increased. Raised SMRs for all-cause and respiratory disease mortality are hardly ever seen in occupational cohorts except for foundry and asbestos workers. Typically, the SMR for all-cause mortality is about 80, and the SMR for most cancer causes about 90 in the absence of exposure to a carcinogen at the site.5 We have observed SMRs for all-cause mortality as low as 60 in UAW vehicle assembly and stamping cohorts.6 We are surprised that these authors mentioned a deficit for all-causes in the abstract of their previous study of this cohort, …
EGFR Tyrosine Kinase Inhibitors Prolong Overall Survival in EGFR Mutated Non-Small-Cell Lung Cancer Patients with Postsurgical Recurrence

It is indisputable that epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) prolong progression-free survival in non-small-cell lung cancer (NSCLC) patients with EGFR mutations better than cytotoxic chemotherapy. However, it is unclear whether EGFR-TKIs prolong the overall survival of NSCLC patients, especially in those with postsurgical recurrence. We retrospectively examined 304 NSCLC patients with known EGFR mutational status (excluding those with squamous cell carcinoma), who had undergone pulmonary resection and experienced postsurgical recurrence. Of these patients, 137 carried EGFR mutations and 167 did not. Of the 137 patients with EGFR mutations, 83 were treated with EGFR-TKIs for their recurrent disease, and 32 of the 167 patients without EGFR mutations were treated with EGFR-TKIs. Postsurgical survival was divided into two parts: recurrence-free survival (RFS) and postrecurrence survival (PRS), and these were compared between the subgroups with a multivariate analysis, adjusted for baseline clinical characteristics. There was no significant difference in RFS between patients with EGFR mutations and those without ( P = 0.88). PRS was also similar in these two subgroups when we excluded patients who had been treated with EGFR-TKIs ( P = 0.64). In patients with EGFR mutations, PRS was significantly longer in those who were treated with EGFR-TKIs than in those who were not given EGFR-TKIs ( P = 0.04). However, among patients without EGFR mutations, PRS was similar in patients who had and had not been treated with EGFR-TKIs ( P = 0.87). In conclusion, Among NSCLC patients with postsurgical recurrence, EGFR-TKIs prolonged PRS in those with EGFR mutations.
To Assess the Quality of Life in Patients Suffering from Allergic Rhinitis

Background : Allergic Rhinitis (AR) associated with impairments in patients day-to-day functioning at home and work is a global health problem. Itâ€™s associated with sleep disorders, emotional problems, impairment in activities, and social functioning. However, itâ€™s not known to what extent quality of life (QOL) scores, work impairment, or sleep is altered in Indian setup hence, this study was designed to assess the quality of life of patients suffering from allergic rhinitis. Methodology : This prospective, observational, cross sectional study was conducted on patients suffering from allergic rhinitis visiting the out patients department. The patients who gave written informed consent were divided into two groups based on gender, Group 1 was males and Group 2 was females. A detailed history was taken and participants underwent thorough medical examination, followed by assessment on Rhino conjunctivitis Quality of Life Questionnaire (RQLQ) and WHOQOL â€“ Bref scores. Results : A total of 87 patients were screened of which 40 patients were enrolled in study. The average age of patients in the study was 28. 08Â±10.01, a total of 26 males and 14 females completed the study. There were significantly worse non nose/eyes symptoms scores, practical problems, and emotional scores in patients in Group 2 as compared to Group 1. Group 1 had better aspect of sleep, nasal symptoms, and eyes symptoms as compared to Group 2. Whereas, Group2 had better aspect of activities score as compared to Group 1. Conclusion : To conclude both groups had compromised quality of life, with females being more affected as compared to males