Miracle-dz/UniFAR-FTUs huggingface dataset:
Improving Early Mobilization in Acute Stroke Patients Through Best Practice Education

Improving Early Mobilization in Acute Stroke Patients Through Best Practice Education by Angela C. Middleton MS, University of Missouri, 2011 BS, University of Missouri, 2004 Project Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Nursing Practice Walden University May 2019 Abstract Nonadherence to best practice guidelines in early mobilization in acute stroke increases the time from admission to mobilization and may increase residual long-term stroke effects. Early mobilization following an acute stroke is known to decrease long-term and secondary disability. The purpose of this project was to decrease the time from admissionNonadherence to best practice guidelines in early mobilization in acute stroke increases the time from admission to mobilization and may increase residual long-term stroke effects. Early mobilization following an acute stroke is known to decrease long-term and secondary disability. The purpose of this project was to decrease the time from admission to mobilization in the acute stroke patient population by improving knowledge of bestpractice guidelines in early mobility using an educational intervention for advanced practice nurse practitioners, physicians, and registered nurses. The practice-focused question for this project asked whether a staff educational program based on best-practice guidelines would decrease the time from admission to early mobilization in the acute stroke patient within the first 48 hours of admission. Rosswurm and Larrabee’s 6-step model was used for this staff education project. A review of the literature indicated sources of evidence from peer-reviewed journals, which were used to support the staff education project and establish best practices in mobilization for the acute stroke patient. A before-and-after design was used to evaluate time from admission to mobilization within the first 48 hours in 40 acute ischemic stroke adult patients following educational intervention for 35 acute stroke staff. Data were collected and analyzed using descriptive statistics. Findings revealed a decrease in time from admission to mobilization by 18.59%. Findings may be used to promote best practices in other units within the hospital and may be used to decrease the residual long-term effects of a stroke, improve activities of daily living, decrease the length of hospital stay, and decrease the long-term cost and
Reversal of diurnal variation in renal function in cases of cirrhosis with ascites.

The mechanism for control of diurnal rhythm of water and electrolyte excretion remains obscure, though the fact that such a cycle occurs was reported by Quincke (1) in 1877 who pointed out that urinary output was appreciably higher during the day in contrast to night. Campbell and Webster (2, 3) observed that the excretion of chlorides and urea was also higher during the day, though creatinine excretion remained more or less at the same level. Subsequent studies (Table I) by Kleitman (4), Simpson (5, 6), Norn (7), Manchester (8), Gerritzen (9), Brod (10), and Sirota, Baldwin, and Villarreal (11) confirmed the observations that urine flow and excretion of certain electrolytes decreased during the hours of deepest sleep in normal individuals. This rhythm was not reversed when normal subjects slept in the daytime and took food and worked at night as reported by Campbell and Webster (2, 3), and confirmed in studies of a night watchman by Jores (12). Gerritzen (13) studied the effect of exposure of four subjects to artificial daylight during the night, and darkness during the day. In three subjects duplication of the rhythm in water and chloride excretion resulted, with two maxima occurring at noon and at midnight. In the fourth subject the rhythm was completely reversed. Borst and de Vries (14) have pointed out the difficulty in evaluating the effect of daylight and of waking on diurnal rhythm, though in some of their subjects the response to the stimulus of daylight was prompt. Jores (12)
Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae

In this review, we provide an overview of protein synthesis in the yeast Saccharomyces cerevisiae. The mechanism of protein synthesis is well conserved between yeast and other eukaryotes, and molecular genetic studies in budding yeast have provided critical insights into the fundamental process of translation as well as its regulation. The review focuses on the initiation and elongation phases of protein synthesis with descriptions of the roles of translation initiation and elongation factors that assist the ribosome in binding the messenger RNA (mRNA), selecting the start codon, and synthesizing the polypeptide. We also examine mechanisms of translational control highlighting the mRNA cap-binding proteins and the regulation of GCN4 and CPA1 mRNAs.
Reciprocal inhibitory interneurones in the Xenopus embryo spinal cord.

The mechanism of reciprocal inhibition between antagonistic motor centres during swimming in the paralysed Xenopus embryo has been investigated further. Paired intracellular recordings have been made from interneurones and motoneurones in an attempt to identify neurones which make direct inhibitory synapses onto motoneurones on the opposite side of the spinal cord. A physiological class of inhibitory interneurones is described which, when stimulated by intracellular current passage, evoke short‐latency, probably monosynaptic, strychnine‐sensitive inhibitory potentials in contralateral motoneurones. These inhibitory interneurones fire once per swimming cycle in phase with the ipsilateral motor root discharge. They therefore have a pattern of activity which would cause them to inhibit motoneurones of the antagonistic motor centre at an appropriate part of the swimming cycle. The intracellular injection of horseradish peroxidase (HRP) has allowed the morphology of these inhibitory interneurones to be characterized. They have unipolar cell bodies with a thick proximal process with short dendrites which crosses the spinal cord ventrally and then bifurcates with one axonal branch ascending into the hind brain and the other descending the spinal cord. These anatomical features are typical of the 'commissural interneurones' first described by Roberts & Clarke (1982). There are also some inhibitory interneurones which can inhibit motoneurones on the same side of the spinal cord. At least some of these interneurones may be commissural interneurones with ipsilateral axons and they may play a role in the generation of the swimming rhythm.
Petrel: Power and Timing Attack Resistant Elliptic Curve Scalar Multiplier Based on Programmable  ${\rm GF}(p)$ Arithmetic Unit

This paper proposes a programmable GF(p) arithmetic unit for elliptic curve cryptography. The proposed unit can perform modular addition, subtraction, multiplication, inversion, and division. A suitable countermeasure against differential power analysis attack and doubling attack is proposed. An elliptic curve scalar multiplication hardware is subsequently designed for the curves defined over GF(p) using two cores of programmable GF(p) arithmetic unit. It performs point doubling and point addition in each iteration concurrently on two cores. The proposed scalar multiplication hardware is implemented on the Xilinx Virtex-2 Pro FPGA platform. The proposed parallel architecture is inherently programmable, memoryless, and resistant against timing and power attacks. It efficiently optimizes area × time per bit value for elliptic curve scalar multiplication.
H3 uridine incorporation in lampbrush chromosomes.

well slide. Each well slide consists of a 3" X 1' microscope slide perforated by a 1/4' hole in the center, sealed by paraffin wax in register with an unperforated slide below. The nuclear membrane was removed free-hand by fine forceps and the well slide at once placed in a sealed chamber containing formaldehyde vapor. The trace of calcium in the saline has no effect on the morphology of the chromosomes but leads to more rapid dispersal of the nuclear sap, thus allowing the chromosomes to spread out and come in contact with the floor of the well slide. Two to 3 hr formaldehyde treatment attaches the chromosomes to this glass surface; thereafter, each well slide can be split into its two component slides, the lower carrying the chromosomes. The fixed preparations were washed with water, treated for 5 min with 5% trichloroacetic acid at 5OC to remove labeled pre-cursor, washed in water again, dehydrated in an ethanol series, washed in xylene to remove paraffin wax, and air-dried from acetone. Kodak AR-10 stripping film was applied and the preparations exposed for from 20 to 100 days at about 17'C. The preparations were developed in Kodak D-19b for 10 min at 17'C, washed in water, fixed for 10 min in Kodak acid fixer, hardened for 10 min in 2% formaldehyde, washed in running water, and air-dried. The chromosomes could not be stained satisfactorily through the film, nor did they show up well by phase contrast under the dry film. However, the contrast is good before drying and the preparations have therefore been pre- served mcist. The film was wetted with distilled water containing a trace of merthiolate as pre-servative and covered with a glass slip. The edges of the slip were sealed with a resin-lanolin cement. Such preparations have now kept satisfactorily for a year.
Closing the gap in academic readiness and achievement: the role of early childcare.

BACKGROUND Socially disadvantaged children with academic difficulties at school entry are at increased risk for poor health and psychosocial outcomes. Our objective is to test the possibility that participation in childcare--at the population level--could attenuate the gap in academic readiness and achievement between children with and without a social disadvantage (indexed by low levels of maternal education). METHODS A cohort of infants born in the Canadian province of Quebec in 1997/1998 was selected through birth registries and followed annually until 7 years of age (n = 1,863). Children receiving formal childcare (i.e., center-based or non-relative out-of-home) were distinguished from those receiving informal childcare (i.e., relative or nanny). Measures from 4 standardized tests that assessed cognitive school readiness (Lollipop Test for School Readiness), receptive vocabulary (Peabody Picture Vocabulary Test Revised), mathematics (Number Knowledge Test), and reading performance (Kaufman Assessment Battery for children) were administered at 6 and 7 years. RESULTS Children of mothers with low levels of education showed a consistent pattern of lower scores on academic readiness and achievement tests at 6 and 7 years than those of highly educated mothers, unless they received formal childcare. Specifically, among children of mothers with low levels of education, those who received formal childcare obtained higher school readiness (d = 0.87), receptive vocabulary (d = 0.36), reading(d = 0.48) and math achievement scores (d = 0.38; although not significant at 5%) in comparison with those who were cared for by their parents. Childcare participation was not associated with cognitive outcomes among children of mothers with higher levels of education. CONCLUSIONS Public investments in early childcare are increasing in many countries with the intention of reducing cognitive inequalities between disadvantaged and advantaged children. Our findings provide further evidence suggesting that formal childcare could represent a preventative means of attenuating effects of disadvantage on children's early academic trajectory.
Reconstruction of Internal Orbital Fractures with Vitallium Mesh

Trauma to the face frequently results in internal orbital fractures that may produce large orbital defects involving multiple walls. Accurate anatomic reconstruction of the bony orbit is essential to maintain normal appearance and function of the eye following such injuries. Autogenous bone grafts do not always produce predictable long-term support of the globe. Displacement and varying amounts of bone-graft resorption can lead to enophthalmos. This study examines the use of Vitallium mesh in the acute reconstruction of internal orbital defects. Fifty-four patients with 66 orbits underwent reconstruction of internal orbital defects with Vitallium mesh. Associated fractures were anatomically reduced and rigidly fixed. Forty-six patients and 57 orbits had adequate follow-up for analysis of results. The average follow-up was 9 months, with 85 percent of the patients followed 6 months or longer. There were no postoperative orbital infections, and none of the Vitallium mesh required removal. Large internal orbital defects can be reconstructed using Vitallium mesh with good results and little risk of infection. Vitallium mesh appears to be well tolerated in spite of free communication with the sinuses. Stable reconstruction of the internal orbit can be achieved and predictable eye position maintained without donor-site morbidity.
What Story Is Told by Oceanic Tracer Concentrations?

In their report “Temporal trends in deep ocean Redfield ratios” (4 Feb., p. [831][1]), Pahlow and Riebesell suggest that the marine biota has changed in the last few decades in response to human activities. These findings challenge the steady-state paradigm of ocean biogeochemistry and might
Leveraging trade opportunities with non-traditional partners: the Malaysia–GCC perspective*

Abstract This paper examines the impact of economic factors on bilateral trade flows between Malaysia and the GCC through estimations of panel data using a gravity model. In particular, the paper compares the determinants of bilateral trade and trade potentials between Malaysia and two regions, the non-traditional Gulf alliance and the traditional ASEAN counterpart, to provide insights for leveraging opportunities through trade with the former. The gravity estimates imply the importance of size effects, similarities in GDP and differences in factor endowments as drivers of trade flows between Malaysia and the GCC, underlying the fact that inter-industry trade dominates these flows. The opposite holds in the case for the Malaysia–ASEAN trade. Though export potentials for industrial products per se appear exhausted in trade with both regions, the Gulf region provides opportunities for Malaysia to export quantity-based final (end-use) products and to diversify its exporting strategy away from quality-based parts and components.
Genetic and phenotypic parameters for carcass traits of American Shorthorn beef cattle.

Carcass measurements were taken on 1,292 steers and collected by the American Shorthorn Association. The sires were purebred or appendix-registered Shorthorn. Because all dams were not Shorthorn, genetic fractions of breeds of origin were determined for each dam. Measurements for hot carcass weight; dressing percentage; fat thickness; ribeye area; kidney, pelvic, and heart fat (KPH); marbling; and yield grade were analyzed jointly with a multivariate REML algorithm to estimate heritabilities of and genetic and phenotypic correlations among the traits. The sire model chosen as best fit of the data included fixed effects of herd of origin (377 classes), slaughter group (118 classes), year of birth (1979-1995), and covariates for linear effects of genetic fractions of breeds (13) of dam and slaughter age, with sire (n=409) as a random effect. Estimates of heritability were . 60+/-. 19, . 49+/-. 19, . 46+/-. 19, . 97+/-. 21, . 45+/-. 19, . 88+/-. 21, and . 54+/-. 19 for previous order of traits, respectively. Most genetic correlations were not significantly different from zero. Genetic correlations of hot carcass weight were significant and positive with dressing percentage (.65+/-.19) and with ribeye area (.70+/-.14). Dressing percentage was significantly positively genetically correlated with ribeye area (.79+/-.16) and negatively genetically correlated with yield grade (-.56+/-.29). Yield grade was also significantly negatively genetically correlated with ribeye area (-.85+/-.10) and positively genetically correlated with fat thickness (.67+/-.15). Most phenotypic correlations were significant and positive. Only the phenotypic correlations of dressing percentage with marbling and with yield grade, and ribeye area with KPH and with marbling were not significantly different from zero. Significant negative correlations were fat thickness with ribeye area (-.16+/-.04) and ribeye area with yield grade (-.61+/-.03). Results seem to indicate that genetic antagonisms between quantity and quality traits were small to moderate. Thus, the opportunity seems to exist for breeding plans to improve carcass quality without having any adverse genetic effect on hot carcass weight, dressing percentage, or ribeye area. The high heritability observed for marbling indicates that a low genetic potential for marbling can be remedied by selection within breed.
An experimental assessment of rotor superconducting stack demagnetization in a liquid nitrogen environment

Stacks of high-temperature superconducting tape have proved to trap in laboratory conditions levels of magnetic flux density one order of magnitude above actual state-of-the-art permanent magnets. Their simple manufacturing, high mechanical properties and intrinsic resistance to sudden quench greatly facilitate their utilization in industrial applications, amongst them, as a source of magnetic flux density in the rotor of electrical machines. For this to happen, the currents induced in the superconducting layers of the stack must not be disturbed during operation. This work studies in experimental conditions the demagnetization of a stack rotating in the airgap of an electrical motor under slot and winding-induced cross-field components, whose values are estimated via conventional 2D finite element analysis. The results are congruent with previous laboratory studies and show small long-term demagnetization rates that may allow operation for time spans longer than initially established.
Stochastic multiscale modeling of crack propagation in random heterogeneous media

A stochastic approach to model crack propagation in random heterogeneous media, using mesoscopic representations of elastic and fracture properties, is presented. In order to obtain reference results, Monte‐Carlo simulations are first conducted on microstructural samples in which a pre‐existing crack is propagated by means of a phase‐field approach. These computations are used to estimate the subscale‐induced randomness on the macroscopic response of the domain. Mesoscopic descriptors are then introduced to investigate scale transition. Elasticity tensor random fields are specifically defined, at that stage, through a moving‐window upscaling approach. The mesoscopic fracture toughness, which is assumed homogeneous and deterministic, is identified by solving an inverse problem involving the macroscopic peak force. A stochastic model is subsequently constructed in which the mesoscopic elasticity is described as a non‐Gaussian random field. This model allows the multiscale‐informed elastic counterpart in the phase‐field formulation to be sampled without resorting to computational homogenization. The results obtained with the sample‐based and model‐based mesoscopic descriptions are finally compared with those corresponding to the full‐scale microscopic model. It is shown, in particular, that the mesoscopic elasticity‐phase‐field formulation associated with statically uniform boundary conditions enables the accurate predictions of the mean elastic response and mean peak force.
A Robust Approach to Mining Repeated Sequence in Audio Stream

In multimedia stream, repeated sequences, e.g., commercials, jingles, usually imply potentially signiﬁcant information. Therefore, mining repeated sequence is an important approach to analyzing multimedia content. This paper reports on a robust unsupervised technique of discovering repeated sequence in audio stream. Different from former research, our approach transforms the repeated sequence detection task into a Hidden Markov Model (HMM) decoding problem in a similarity trellis. To resist the false and missing matches in real application, we present a soft deﬁnition of repeated sequence, termed as maximal loosely repeated sequence (MLRS), as the objective for detection, and use a Viterbi-like algorithm to mine all the MLRSs in the stream. In addition, we propose a novel metric to evaluate the repeated sequence detection algorithm. Experiments both on simulated data and real broadcast data demonstrate the effectiveness of our method.
Neonatal herpes virus infection and extracorporeal life support

Objectives: To investigate outcomes among neonates with herpes virus infection reported to the Extracorporeal Life Support Organization (ELSO) Registry and analyze factors associated with death before hospital discharge with this virus. Currently, scant data exist regarding extracorporeal membrane oxygenation support in neonates with herpes virus infection. Design: Retrospective analysis of ELSO Registry data set from 1985 to 2005. Setting: A total of 114 extracorporeal membrane oxygenation centers contributing data to the ELSO Registry. Patients: Patients, 0 to 31 days of age, with herpes simplex virus infection supported with extracorporeal membrane oxygenation and reported to the ELSO Registry. Interventions: None. Measurements and Main Results: Clinical characteristics, outcomes, and factors associated with death before hospital discharge were investigated for patients in the virus group. Kaplan-Meier estimates of survival to hospital discharge according to virus type were investigated. Newborns with herpes simplex virus infection requiring extracorporeal membrane oxygenation support demonstrated much lower hospital survival rates (25%). Clinical presentation with septicemia/shock was significantly associated with mortality for the herpes simplex virus group on multivariate analysis. There was no difference in herpes simplex virus mortality when comparing two eras (≥2000 vs. <2000). Conclusions: In this cohort of neonatal patients with overwhelming infections due to herpes simplex virus who were supported with extracorporeal membrane oxygenation, survival was dismal. Patients with disseminated herpes simplex virus infection presenting with septicemia/shock are unlikely to survive, even with aggressive extracorporeal support.