Miracle-dz/UniFAR-FTUs huggingface dataset:
Deep Learning Inference in Facebook Data Centers: Characterization, Performance Optimizations and Hardware Implications

The application of deep learning techniques resulted in remarkable improvement of machine learning models. In this paper provides detailed characterizations of deep learning models used in many Facebook social network services. We present computational characteristics of our models, describe high performance optimizations targeting existing systems, point out their limitations and make suggestions for the future general-purpose/accelerated inference hardware. Also, we highlight the need for better co-design of algorithms, numerics and computing platforms to address the challenges of workloads often run in data centers.
Overview of Multicarrier CDMA

This chapter contains sections titled: Introduction Overview of Multicarrier CDMA Systems Channel Model Performance of MC-CDMA System Performance of Overlapping Multicarrier DS-CDMA Systems Performance of Multicarrier DS-CDMA-I Systems Performance of AMC DS-CDMA Systems Performance of SFH/MC DS-CDMA Systems Chapter Summary and Conclusion ]]>
Aspirin, NSAIDs, and Glioma Risk: Original Data from the Glioma International Case–Control Study and a Meta-analysis

Background: There have been few studies of sufficient size to address the relationship between glioma risk and the use of aspirin or NSAIDs, and results have been conflicting. The purpose of this study was to examine the associations between glioma and aspirin/NSAID use, and to aggregate these findings with prior published studies using meta-analysis. Methods: The Glioma International Case-Control Study (GICC) consists of 4,533 glioma cases and 4,171 controls recruited from 2010 to 2013. Interviews were conducted using a standardized questionnaire to obtain information on aspirin/NSAID use. We examined history of regular use for ≥6 months and duration-response. Restricted maximum likelihood meta-regression models were used to aggregate site-specific estimates, and to combine GICC estimates with previously published studies. Results: A history of daily aspirin use for ≥6 months was associated with a 38% lower glioma risk, compared with not having a history of daily use [adjusted meta-OR = 0.62; 95% confidence interval (CI), 0.54–0.70]. There was a significant duration-response trend (P = 1.67 × 10−17), with lower ORs for increasing duration of aspirin use. Duration-response trends were not observed for NSAID use. In the meta-analysis aggregating GICC data with five previous studies, there was a marginally significant association between use of aspirin and glioma (mOR = 0.84; 95% CI, 0.70–1.02), but no association for NSAID use. Conclusions: Our study suggests that aspirin may be associated with a reduced risk of glioma. Impact: These results imply that aspirin use may be associated with decreased glioma risk. Further research examining the association between aspirin use and glioma risk is warranted.
Late Cretaceous sauropod tooth morphotypes may provide supporting evidence for faunal connections between North Africa and Southern Europe

The Cretaceous Kem Kem beds of Morocco and equivalent beds in Algeria have produced a rich fossil assemblage, yielding, amongst others, isolated sauropod teeth, which can be used in species diversity studies. These Albian-Cenomanian (∼113–93.9 Ma) strata rarely yield sauropod body fossils, therefore, isolated teeth can help to elucidate the faunal assemblages from North Africa, and their relations with those of contemporaneous beds and geographically close assemblages. Eighteen isolated sauropod teeth from three localities (Erfoud and Taouz, Morocco, and Algeria) are studied here, to assess whether the teeth can be ascribed to a specific clade, and whether different tooth morphotypes can be found in the samples. Two general morphotypes are found, based on enamel wrinkling and general tooth morphology. Morphotype I, with mainly rugose enamel wrinkling, pronounced carinae, lemon-shaped to (sub)cylindrical cross-section and mesiodistal tapering towards an apical tip, shows affinities to titanosauriforms and titanosaurs. Morphotype II, characterized by more smooth enamel, cylindrical cross-section, rectangular teeth with no apical tapering and both labial and lingual wear facets, shows similarities to rebbachisaurids. Moreover, similarities are found between these northwest African tooth morphotypes, and tooth morphotypes from titanosaurs and rebbachisaurids from both contemporaneous finds from north and central Africa, as well as from the latest Cretaceous (Campanian–Maastrichtian, 83.6 Ma–66.0 Ma) of the Ibero-Armorican Island. These results support previous hypotheses from earlier studies on faunal exchange and continental connections between North Africa and Southern Europe in the Cretaceous.
Tender Joint Count and Inflammatory Activity in Patients With Established Rheumatoid Arthritis: Results From a Longitudinal Study

The tender joint count (TJC) is included in composite disease activity scores (CDAS) (the Disease Activity Score in 28 joints, the Clinical Disease Activity Index, and the Simplified Disease Activity Index). The impact of having predominantly tender joints was explored by use of the Tender‐Swollen Joint Count Difference (TSJD), and ultrasound (US) provided a measure of joint inflammation. The current study aimed to explore the cross‐sectional and longitudinal associations between the TSJD and a spectrum of outcome measures, including US scores in patients with established rheumatoid arthritis (RA) during follow‐up and while receiving treatment with biologic disease‐modifying antirheumatic drugs (bDMARDs).
A Critic on Real-Time Scheduling Strategies

The present scenario of the computing era is dominated by the real-time systems. The real-time systems are gaining popularity in the field of job scheduling as both uni-processor and multi-processor architectures to satisfy the requirements of time-constrained applications like flight controls, avionics, multimedia data streaming, etc. The application areas are also growing by huge amounts due to increasing human dependency on machines. Hence to balance between ever-increasing needs and exponentiallyrising overheads; the necessity of new approaches, which can ensure the best results not only limited to reliable logical results but also acceptable temporal results too, is expected to increase. This paper reviews various existing scheduling algorithms suggesting further dissimilar techniques and endeavors to compare and suggest which approach best suits which scenarios based on their primary pluses.
FGF23 Induction of O-Linked N-Acetylglucosamine Regulates IL-6 Secretion in Human Bronchial Epithelial Cells

The hexosamine biosynthetic pathway (HBP) generates the substrate for the O-linked β-N-acetylglucosamine (O-GlcNAc) modification of proteins. The HBP also serves as a stress sensor and has been reported to be involved with nuclear factor of activated T-cells (NFAT) activation, which can contribute to multiple cellular processes including cell metabolism, proliferation, and inflammation. In our previously published report, Fibroblast Growth Factor (FGF) 23, an important endocrine pro-inflammatory mediator, was shown to activate the FGFR4/phospholipase Cγ (PLCγ)/nuclear factor of activated T-cells (NFAT) signaling in chronic inflammatory airway diseases such as cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD). Here, we demonstrate that FGF23 increased the O-GlcNAc modification of proteins in HBECs. Furthermore, the increase in O-GlcNAc levels by FGF23 stimulation resulted in the downstream activation of NFAT and secretion of interleukin-6 (IL-6). Conversely, inhibition of FGF23 signaling and/or O-GlcNAc transferase (OGT)/O-GlcNAc reversed these effects. Collectively, these data suggest that FGF23 induced IL-6 upregulation and secretion is, at least, partially mediated via the activation of the HBP and O-GlcNAc levels in HBECs. These findings identify a novel link whereby FGF23 and the augmentation of O-GlcNAc levels regulate airway inflammation through NFAT activation and IL-6 upregulation in HBECs. The crosstalk between these signaling pathways may contribute to the pathogenesis of chronic inflammatory airway diseases such as COPD and CF as well as metabolic syndromes, including diabetes.
Preference learning for machine translation

Automatic translation of natural language is still (as of 2017) a long-standing but unmet promise. While advancing at a fast rate, the underlying methods are still far from actually being able to reliably capture syntax or semantics of arbitrary utterances of natural language, way off transporting the encoded meaning into a second language. However, it is possible to build useful translating machines when the target domain is well known and the machine is able to learn and adapt efficiently and promptly from new inputs. This is possible thanks to efficient and effective machine learning methods which can be applied to automatic translation. In this work we present and evaluate methods for three distinct scenarios: a) We develop algorithms that can learn from very large amounts of data by exploiting pairwise preferences defined over competing translations, which can be used to make a machine translation system robust to arbitrary texts from varied sources, but also enable it to learn effectively to adapt to new domains of data; b) We describe a method that is able to efficiently learn external models which adhere to fine-grained preferences that are extracted from a constricted selection of translated material, e.g. for adapting to users or groups of users in a computer-aided translation scenario; c) We develop methods for two machine translation paradigms, neural- and traditional statistical machine translation, to directly adapt to user-defined preferences in an interactive post-editing scenario, learning precisely adapted machine translation systems. In all of these settings, we show that machine translation can be made significantly more useful by careful optimization via preference learning.
Prevalence and Risk Factors of Chronic Rhinosinusitis in the Elderly Population of Korea

Background Although a significant number of the clinical features and pathophysiologic mechanisms of chronic rhinosinusitis (CRS) have been described, only a few studies have been published on characterization of CRS in the field of aging. Objective We investigated the prevalence and risk factors of CRS in elderly (≥65 years old) Koreans using large-scale nationwide epidemiological data and compared the risk factors of elderly with those of younger adult participants (19–64 years old). Methods Data from 25 529 participants who completed the 2008–2012 Korean National Health and Nutrition Examination Survey were analyzed. Diagnosis of CRS was done according to the EP3OS 2012 guideline for epidemiologic study. Risk factors of CRS were compared in the aspects of sociodemographics, general health behaviors, clinical characteristics, and comorbidities of participants. Results The prevalence of CRS was significantly higher in 5590 elderly than in 19 939 younger adults (6.55% vs 5.69%; P = .016. Some variables of socioeconomic status and mental health in the adult group were associated with increased risk of CRS but did not show association in the elderly group. We observed a significant association between CRS prevalence and comorbid allergic rhinitis, asthma, and atopic dermatitis in both groups (P < .05). However, in the elderly group, the associations were significantly weaker with regard to allergic rhinitis (P-interaction = .03) and asthma (P-interaction = .002). Conclusion These results suggest that elderly populations have distinct pathophysiology and clinical presentations from adult CRS, and management for elderly patients with CRS may require different or additional therapeutic approaches.
THE FUNCTION OF THE DIAPHRAGM

The relationship between the action of the diaphragm and the intercostal muscles, as well as the muscles of less importance, in making respiration possible by rhythmically enlarging and decreasing the volume of the thoracic cavity has been the subject of discussion by clinicians, surgeons and physiologists. Many valuable observations have been made which, at the present time, form a background for further observation and a fund of information from which to draw, as need arises, during the progress of research. In time, certain fixed opinions become accepted as facts, often because they are stated with emphasis, owing to the conviction of their authors. As truth is relative and corresponds with the best thought of a period, these opinions are true unless they can be proved incorrect, inaccurate or incomplete. For one to replace an old truth by a wider and more accurate conception of fact requires that the observer make
Assessment of Patient and Occupational Safety Culture in Hospitals: Development of a Questionnaire with Comparable Dimensions and Results of a Feasibility Study in a German University Hospital

(1) Background: Both patient and occupational safety cultures should be considered when promoting safety culture. To our knowledge, there are no studies that capture patient safety culture (PSC) and occupational safety culture (OSC) in hospitals while using a common questionnaire. The aim of this feasibility study in a German university hospital was to develop a questionnaire to assess both issues analogously. In addition to feasibility outcomes, we report results of PSC-OSC comparisons. (2) Methods: To assess PSC, we used the existing Hospital Survey on Patient Safety Culture (HSPSC) questionnaire. Developing new OSC “twin items” for certain parts of the HSPSC was supported by a previous literature review. Additionally, we developed multiple choice questions to examine knowledge and competencies regarding specific PS/OS aspects. (3) Results: Developing and implementing a combined PSC and OSC assessment instrument was feasible. The overall response rate was 33% (407 nurses, 140 physicians). In general, the statistical reliability of almost all scales was sufficient. Positive PSC perceptions (agreement rates 46–87%) were found in 16 out of 18 scales. Of the four twin scales, the PSC values were significantly better. Individual PS- and OS-related knowledge and competencies were lower than expected. (4) Conclusion: The comparative investigation of patient and occupational safety in a large hospital is a promising approach and can be recommended for further studies. We used our experiences that are presented here in an ongoing bicentric study on the associations between working conditions, occupational safety culture, patient safety culture, and patient safety outcomes (WorkSafeMed).
Complement-Free Couples Must Communicate: A Hardness Result for Two-Player Combinatorial Auctions

We study the communication complexity of welfare maximization in combinatorial auctions with $m$ items and two subadditive bidders. A $\frac{1}{2}$-approximation can be guaranteed by a trivial randomized protocol with zero communication, or a trivial deterministic protocol with $O(1)$ communication. We show that outperforming these trivial protocols requires exponential communication, settling an open question of [DobzinskiNS10, Feige09]. Specifically, we show that any (randomized) protocol guaranteeing a $(\frac{1}{2}+\frac{6}{\log_2 m})$-approximation requires communication exponential in $m$. This is tight even up to lower-order terms: we further present a $(\frac{1}{2}+\frac{1}{O(\log m)})$-approximation in poly($m$) communication. To derive our results, we introduce a new class of subadditive functions that are "far from" fractionally subadditive functions, and may be of independent interest for future works. Beyond our main result, we consider the spectrum of valuations between fractionally-subadditive and subadditive via the MPH hierarchy. Finally, we discuss the implications of our results towards combinatorial auctions with strategic bidders.
Work stress and the risk of cancer: A meta‐analysis of observational studies

Epidemiological studies have explored the relationship between work stress and the risk of cancer, but it remains unclear on whether work stress could increase the risk of cancer, or by other factors such as smoking and physical activity. Our study aimed to investigate the association between work stress and the risk of cancer and in relation to major potential confounding and modifying factors. We systematically searched three electronic databases, hand‐searched references and citations of retrieved articles, and consulted experts to identify studies on assessing the association between work stress and the risk of cancer. The relative risks (RRs) of cancer associated with work stress were estimated using a random‐effects model, and stratified by exposure measurement, study design, gender, study location, cancer site, smoking, drinking, body mass index, and physical activity. A total of 281,290 participants were included in this analysis. The significant association between work stress and the risk of colorectal (RR = 1.36; 95%CI: 1.16–1.59), lung (RR = 1.24; 95%CI: 1.02–1.49), and esophagus (RR = 2.12; 95%CI: 1.30–3.47) cancers were found. A statistically significant effect of work stress on colorectal cancer risk was observed in North America (RR = 1.51, 95% CI: 1.23–1.86, but not significant in Europe (RR = 1.16, 95% CI: 0.90–1.48). By contrast, a significant association between work stress and esophagus cancer was found in Europe, but not in North America. In addition, we did not observe any association between work stress and the risk of prostate, breast, or ovarian cancers. Findings of our study show that work stress is an important risk factor for colorectal, lung, and esophagus cancers. General public should be aware of the increased risk of cancer in employers with work stress. More efforts should be focused on understanding and studying the potential mechanisms which would help to identify employees at higher risk of these cancers.
Results from New Zealand's 2018 Report Card on Physical Activity for Children and Youth.

In New Zealand (NZ), 88% of health loss is now caused by noncommunicable diseases, in part attributed to low levels of physical activity (PA) and high levels of inactivity, and the downstream impacts of these, including suboptimal blood glucose profiles, body size, and blood pressure.1 While the NZ 2016 PA Report Card on Physical Activity for Children and Youth2 revealed relatively high levels of PA, approximately one-third of NZ children and youth did not meet PA recommendations of ≥60 minutes of moderate-to-vigorous physical activity (MVPA) per day. The purpose of this paper is to summarize the methods for grade calculation and results of the 2018 update of the PA Report Card for NZ.
Low-Voltage OTA–C Filter With an Area- and Power-Efficient OTA for Biosignal Sensor Applications

This paper presents a systematic method for decreasing the amount of transconductors used by an operational transconductance amplifier–capacitor (OTA–C) filter to decrease the power consumption and the active area. An OTA with a local-feedback linearized technique and a transconductance booster is proposed based on the presented method. The proposed OTA combines current division with source degeneration to enhance linearity and implement low transconductance. This topology enables the proposed OTA to drive multiple integration capacitors without an additional output stage. The OTA-based circuit realizes low power consumption by operating under a weak inversion at a supply voltage of 1 V. Thus, a fifth-order ladder-type low-pass Butterworth OTA–C filter is implemented for the acquisition of electrocardiograph signals. The proposed method is validated using a prototype fabricated through a 1P6M 0.18-μm CMOS process. Results show that in ECG signal acquisition, the proposed filter has a signal bandwidth located within 250 Hz, a dynamic range of 61.2 dB, and a power consumption of 41 nW to achieve a figure-of-merit of 5.4 × 10−13. The active area of the filter is 0.24 mm2.
Findings during screening colonoscopies in a Middle Eastern cohort

Background/Aims: Colorectal cancer is the most common cancer in males and the third most common cancer in females. We aim to determine the polyp and adenoma prevalence in a cohort of patients who underwent opportunistic screening colonoscopies. Patients and Methods: A retrospective cohort study was conducted using an endoscopic reporting database of individuals seen at three tertiary care hospitals (two public hospitals and one private) in Riyadh, Saudi Arabia. Consecutive patients who were 45 years of age and older and underwent opportunistic screening colonoscopies between November 2016 and October 2017 were included. We excluded those with a history of colon cancer or colonic resection for any reason, inflammatory bowel disease, gastrointestinal bleeding, or anemia. Results: Around 1180 patients were included in the study with a mean age of 58.6 years (SD = 7.3), with males representing 53.6% and an overall cecal intubation rate of 92.4%. Masses were found in 1.6% of the study population (50% in the sigmoid or rectosigmoid, 37.5% in the rectum). The polyp detection rate in colonoscopies was 24.8% and the adenoma detection rate was 16.8%. The histology of removed polyps was tubular adenomas in 56.6%, hyperplastic polyps in 32.7%, tubulovillous adenomas in 8.2%, and villous adenomas in 2.5%. The majority of the polyps were in the sigmoid colon (28.3%) and rectum (22.0%), followed by the ascending colon (11.2%) and cecum (10.3%), then the transverse colon and descending colon (9.4% each), and multiple locations in the remainder. Conclusion: The prevalence of polyps and adenomas in this cohort is less than that reported in the Western populations.
An iterative incidence angle normalization algorithm for sea ice SAR images

For automated interpretation of the sea ice SAR data, the change in backscatter level due to the incidence angle variation should be taken into account. We have studied the statistics of the Radarsat ScanSAR Narrow data for sea ice, and developed an iterative algorithm for normalizing the data for automated interpretation of it.
RGB-D Based Action Recognition with Light-weight 3D Convolutional Networks

Different from RGB videos, depth data in RGB-D videos provide key complementary information for tristimulus visual data which potentially could achieve accuracy improvement for action recognition. However, most of the existing action recognition models solely using RGB videos limit the performance capacity. Additionally, the state-of-the-art action recognition models, namely 3D convolutional neural networks (3D-CNNs) contain tremendous parameters suffering from computational inefficiency. In this paper, we propose a series of 3D light-weight architectures for action recognition based on RGB-D data. Compared with conventional 3D-CNN models, the proposed light-weight 3D-CNNs have considerably less parameters involving lower computation cost, while it results in favorable recognition performance. Experimental results on two public benchmark datasets show that our models can approximate or outperform the state-of-the-art approaches. Specifically, on the RGB+D-NTU (NTU) dataset, we achieve 93.2% and 97.6% for cross-subject and cross-view measurement, and on the Northwestern-UCLA Multiview Action 3D (N-UCLA) dataset, we achieve 95.5% accuracy of cross-view.