Miracle-dz/UniFAR-FTUs huggingface dataset:
The Sacred Groves and Their Significance in Conserving Biodiversity An Overview

Sacred groves are tracts of virgin forest with rich diversity, which have been protected by the local people for centuries for their cultural and religious beliefs and taboos that the deities reside in them and protect the villagers from different calamities. Every sacred grove carries its own legends, lore, and myths which form the integral part of the sacred grove. An inextricable link between present society and past in terms of biodiversity, culture, religious and ethnic heritage exists in sacred groves. Sacred groves are distributed across the globe, and diverse cultures recognize them in different ways encoding various rules for their protection. Sacred groves occur in many parts of India viz., Western Ghats, Central India, northeast India, etc. particularly where the indigenous communities live. These are known by different names given to them by the ethnic people. Sacred groves act as an ideal centre for biodiversity conservation. Several plants and animals that are threatened in the forest are still well c onserved in some of the sacred groves. It has been observed that several medicinal plants that are not to be found in the forest are abundant in the sacred groves. Further, rare, endangered, threatened and endemic species are often concentrated in sacred groves. The sacredness, religious beliefs and taboos play a significant role in promoting sustainable utilization and conservation of flora and fauna of the region. However, with the passage of time, considerable changes have taken place in the extent of the sacred groves, in their vegetation structure, peoples’ perception towards them and the religious beliefs and taboos. Therefore, a holistic understanding of the current status, structure and function of sacred grove is essential for assessing their ecological role and formulating strategies for their conservation. This paper briefly reviews the studies on sacred groves across the globe in general and India in particular, highlighting that the tradition of sacred groves could provide a powerful tool for ensuring biodiversity conservation through community participation.
Prevalence and characterisation of sexual dysfunctions in women, in 12 colombian cities, 2009-2016

Objective: To determine the prevalence and characterisation of sexual dysfunctions in a population of sexually active women with ages ranging between 18 and 72 years, in 12 Colombian cities.Materials and methods: Descriptive crosssectional study that included women 18 years of age and older, sexually active within the past six weeks, living in Colombia. Excluded were illiterate and pregnant women, women in the first 6 months postpartum, women with a psychiatric disease or neurological deficit, and women with a history of cancer. The study was conducted in healthcare centres in twelve cities (Bogota, Medellin, Cali, Barranquilla, Cartagena, Cucuta, Ibague, Bucaramanga, Villavicencio, Pereira, Manizales and Armenia) between June 2009 and December 2016. A consecutive sampling method was used. The “Female Sexual Function Index” validated in Spanish was applied. Sociodemographic variables, a history of sexual and reproductive health, sexual behaviour, and frequency of overall sexual dysfunction and by type of dysfunction assessed were measured. A descriptive analysis of the data was performed using absolute and relative measurements. A stratified description was made by age under or over 40 years.Results: Of a total of 72,894 candidates for enrolment, 50,991 (69,95%) were ultimate analysed. Mean age was 30.9±10.8 years. The prevalence of sexual dysfunction in the study group was 32.97% (16,812 women). The score on the FSFI in the affected women was 24.07±6.18 points. Issues were found with libido in 32.97%, orgasm in 21.93%, arousal in 16,86%, lubrication in 14,79%, and pain in 7.56%. Median sexual dysfunction per woman was 2, found in 64.16%. Conclusion: Among Colombian women, a prevalence of sexual dysfunction is found in close to one-third of the population, characterised mainly by issues with libido and orgasm. Interventions are required in order to establish an immediate diagnostic and therapeutic plan.
Eval stud too

Material and methods. Twenty-nine dental technician students (DTS group) and 30 graduate dentists (GD group) participated in this study. The Toothguide Training Box (TTB) was used to train the participants and test their shadematching abilities. Shade-matching ability was evaluated with 3 exercises and a final test, all of which are components of the TTB. The number of mistakes for each participant for value (L), chroma (c), and hue (h) were recorded during the exercises and the final test, and the mistake ratios were calculated. Color difference (DE) values for each shade were calculated from the L*, a*, and b* values of the Vita 3D-Master shade guide for each participant in both groups. The Mann-Whitney U test was used to determine statistically significant differences between the L, c, and h mistake ratios of the 2 groups, and the Student t test was used to determine statistically significant differences between the final test scores and the DE values of the groups (a1⁄4.05).
Hypertensive Rats Sex-related Differences in Mast Cell Activity and Doxorubicin Toxicity : A Study in Spontaneously

Clinically, girls appear to be more sensitive than boys to the cardiotoxic effects of doxorubicin, whereas the opposite may be true for adults. To identify and characterize potential sex-related differences, adult male and female spontaneously hypertensive rats (SHR; some ovariectomized [OVX]) received 1 mg/kg of doxorubicin or saline iv weekly for 9, 10, or 12 weeks. Weight gain was slower in treated males. Serum concentrations of cholesterol and triglycerides increased and those of albumin decreased in both sexes, but changes were more pronounced in treated males. Treated males had significantly more severe cardiomyopathy scores and higher serum levels of cTnT than females. The increased cardiotoxicity was accompanied by higher numbers of cardiac mast cells (MCs) and percentage of cardiac MCs undergoing degranulation. Doxorubicin-treated OVX animals had significantly increased numbers of cardiac MCs, more severe myocardial lesions, and elevated serum concentrations of cTnT compared to doxorubicin-treated normal female SHR. The severity of cardiac lesions in the OVX female was similar to that observed in doxorubicin-treated males. This study demonstrated the presence of sex-related differences in the cardiotoxic effects elicited by doxorubicin and identified variations in the level of cardiac MC activity as a factor which could possibly contribute to the male-female dissimilarity.
Author ’ s Accepted Manuscript Aberrant Temporal Connectivity in Persons at Clinical High Risk for PsychosisFunctional Dysconnectivity in the Clinical High Risk

Background Schizophrenia, a neurodevelopmental disorder, involves abnormalities in functional connectivity (FC) across distributed neural networks, which are thought to antedate the emergence of psychosis. In a cohort of adolescents and young adults at clinical high risk (CHR) for psychosis, we applied data-driven approaches to resting-state fMRI data so as to systematically characterize FC abnormalities during this period and determine whether these abnormalities are associated with psychosis risk and severity of psychotic symptoms. Methods Fifty-one CHR participants and 47 matched healthy controls (HCs) were included in our analyses. Twelve of these CHR participants developed psychosis within 3.9 years. We estimated one multivariate measure of FC and studied its relationship to CHR status, conversion to psychosis and positive symptom severity. Results. Multivariate analyses revealed between-group differences in whole-brain connectivity patterns of bilateral temporal areas, mostly affecting their functional connections to the thalamus. Further, more severe positive symptoms were associated with greater connectivity abnormalities in the anterior cingulate and frontal cortex. Conclusions Our study demonstrates that the well-established FC abnormalities of the thalamus and temporal areas observed in schizophrenia are also present in the CHR
Measuring quality and non-cost competitiveness at a country-product level

This paper contributes to the ongoing debate on macroeconomic imbalances and external competitiveness by developing a set of indicators of export capability at a country-product level which can be used to complement the existing toolkit of instruments based mostly on unit labour costs and relative price levels. A micro-founded methodology is here proposed to extract information on the capacity of a country's exporters to compete abroad by combining trade and macroeconomic data. In particular, light is shed on two independent components of demand for a particular variety (country-product combination): markups-shifting "quality" and sales-boosting "non-cost competitiveness". Together with cost efficiency and information on foreign prices and consumption, these additional indicators may foster our understanding of the determinants of a country's external position, thus providing better guidance for policymaking.
Sexuality and Pregnancy in the Setting of Early , Middle , and Late Adolescence

The objectives of this article are to review current contraceptive methods available to adolescents and to provide information, guidance, and encouragement to pediatric clinicians to enable them to engage in informed up-to-date interactions with their sexually active adolescent patients. Pregnancy prevention is a complex and dynamic process, and young people benefit from having a reliable authoritative source for information, counseling, and support. Clinicians who provide services for adolescents have a responsibility to develop their skills and knowledge base so that they can serve as that source. This review begins with a discussion about adolescent sexuality and pregnancy in the context of the adolescent developmental stages. We discuss approaches to introduce the topic of contraception during the clinic visit and contraceptive counseling techniques to assist with the discussion around this topic. In addition, information is included regarding confidential services, support of parental involvement, and the importance of male
Prognosis of morbidity on type 2 diabetes according to the FINDRISC questionnaire — preliminary study

Introduction. Diabetes is not only an issue related to secretory organs or complications permanently attached to any ongoing disease process, but it is also an issue of public health as it is one of the four top priority non-contagious diseases the entire world is fighting against. The aim of this research was to assess the risk of possible diabetes incidence amongst a group of test subjects which may occur in the next decade. The study was based on a FINDRISC questionnaire. Material and methods. The research group were comprised of 100 responders at the ages of 18 to 88, including 70 female and 30 male subjects. The mean age of the men was 47.6 ± 19.98 years, while for the women it was 53.61 ± 18.31 years. Results. The results obtained in the questionnaire showed that the risk of diabetes incidence increased in subjects who turned 55 years of age in comparison to the younger responders. The risk of developing diabetes increased with the increase of BMI at the correlation coefficient 0.657 and p < 0.001. Conclusions. Genetic affinity was determined to be an irrelevant variable in the risk of developing diabetes. Both BMI and the age were strong factors determining the future risk of diabetes incidence.
Unemployment and liquidity constraints

We present a dynamic framework for the interaction between borrowing (liquidity) constraints and deviations of actual hours from desired hours, both measured by discrete-valued indicators, and estimate it as a system of dynamic binary and ordered probit models with panel data from the Panel Study of Income Dynamics. We analyze a household's propensity to be liquidity constrained by means of a dynamic binary probit model. We analyze qualitative aspects of the conditions of employment, namely whether the household head is involuntarily overemployed, voluntarily employed, or involuntarily underemployed or unemployed, by means of a dynamic ordered probit model. We focus on the possible interaction between the two types of constraints. We estimate these models jointly using maximum simulated likelihood, where we allow for individual random effects along with an autoregressive process for the general error term in each equation. A novel feature of our method is that it allows for the random effects to be correlated with regressors in a time-invariant fashion. Our results provide strong support for the basic theory of constrained behavior and the interaction between liquidity constraints and exogenous constraints on labor supply. Copyright © 2007 John Wiley & Sons, Ltd.
comparing outcome and costs since the 1970 s Intermediate-dose versus high-dose prophylaxis for severe hemophilia :

http://bloodjournal.hematologylibrary. org/content/122/7/1129.full. html Updated information and services can be found at: (721 articles) Thrombosis and Hemostasis (325 articles) Pediatric Hematology (2515 articles) Free Research Articles (3886 articles) Clinical Trials and Observations Articles on similar topics can be found in the following Blood collections http://bloodjournal.hematologylibrary. org/site/misc/rights.xhtml#repub_requests Information about reproducing this article in parts or in its entirety may be found online at: http://bloodjournal.hematologylibrary. org/site/misc/rights.xhtml#reprints Information about ordering reprints may be found online at: http://bloodjournal.hematologylibrary. org/site/subscriptions/index.xhtml Information about subscriptions and ASH membership may be found online at:
Taking Credit: Redistribution and Borrowing in an Age of Economic Polarization

Several recent studies link rising income inequality in the United States to the global financial crisis, arguing that US politicians did not respond to growing inequality with fiscal redistribution. Instead, Americans saved less and borrowed more to maintain relative consumption in the face of widening economic disparities. This article proposes a theory in which fiscal redistribution dampens the willingness of citizens to borrow to fund current consumption. A key implication is that pretax inequality will be more tightly linked with credit in less redistributive countries. The long-run partisan composition of government is, in turn, a key determinant of redistributive effort. Examining a panel of eighteen OECD democracies, the authors find that countries with limited histories of left-wing participation in government are significantly more likely see credit expansion as prefisc inequality grows compared to those in which the political left has been more influential.
chronic pancreatitis HP : hereditary pancreatitis Penetrance : the probability that an individual with a particular genotype expresses a particular phenotype Expressed pseudogene : a transition state between a functioning duplicated gene and a nonfunctional pseudogene INTRODUCTION Chronic pancreatit

Chronic pancreatitis (CP) is a persistent inflammation of the pancreas. Over the past 12 years, genetic studies of hereditary, familial, and idiopathic forms of CP have made great progress in defining the disease pathogenesis. Identification of gain-of-function missense and copy number mutations in the cationic trypsinogen gene (PRSS1) and lossof-function variants in both the pancreatic secretory trypsin inhibitor (SPINK1) and chymotrypsinogen C (CTRC ) genes has firmly established the pivotal role of prematurely activated trypsin within the pancreas in the etiology of CP. Loss-of-function variants in the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-sensing receptor (CASR) genes also increase the risk of CP. Here, we review recent developments in this rapidly evolving field, highlight the importance of gene-gene and gene-environment interactions in causing the disease, and discuss the opportunities and challenges in identifying novel genetic factors that affect susceptibility/resistance to CP. 63 A nn u. R ev . G en om . H um an G en et . 2 00 9. 10 :6 387 . D ow nl oa de d fr om w w w . a nn ua lr ev ie w s. or g by B ro w n U ni ve rs ity o n 11 /0 7/ 12 . F or p er so na l u se o nl y. ANRV386-GG10-04 ARI 29 July 2009 0:43 CP: chronic pancreatitis HP: hereditary pancreatitis Penetrance: the probability that an individual with a particular genotype expresses a particular phenotype Expressed pseudogene: a transition state between a functioning duplicated gene and a nonfunctional pseudogene INTRODUCTION Chronic pancreatitis (CP) is a persistent inflammation of the pancreas characterized by repeated attacks of abdominal pain, irreversible morphological changes, and impairment of both exocrine and endocrine functions (38, 142). Hereditary pancreatitis (HP) is a rare form of CP that is inherited as an autosomal dominant disease with approximately 80% penetrance and variable expression (37). Nonetheless, molecular genetic studies of HP have provided the strongest support for the 100-year-old hypothesis that pancreatitis is an autodigestive disease in which prematurely activated trypsin within the pancreas was thought to play a pivotal role in triggering the activation cascade of all pancreatic digestive zymogens (29). This article critically reviews the many exciting genetic findings made over the past 12 years in a historical context (Figure 1), highlights their impact on defining the early events in the development of CP, and discusses the opportunities and challenges in identifying novel disease susceptibility/resistance genetic factors. For ease of discussion, a brief description of the five CP-associated genes is given in Table 1. Given the central role of intrapancreatic trypsinogen 1996 200
Running title : GLUT 1 and SVCT 2 function in choroid plexus papilloma *

In vitro and in vivo studies suggest that the basolateral membrane of choroid plexus cells, which is in contact with blood vessels, is involved in the uptake of the reduced form of vitamin C, ascorbic acid, through the sodium-vitamin C cotransporter, SVCT2. Moreover, very low levels of vitamin C were observed in the brains of SVCT2-null mice. The oxidized form of vitamin C, dehydroascorbic acid, is incorporated through the facilitative glucose transporters, GLUTs. In this study, the contribution of SVCT2 and GLUT1 to vitamin C uptake in human choroid plexus papilloma cells in culture was examined. Both the functional activity and the kinetic parameters of GLUT1 and SVCT2 in cells isolated from human choroid plexus papilloma was observed. Finally, dehydroascorbic acid uptake by GLUT1 in choroid plexus cells was assessed in the A cc ep te d A rt ic le This article is protected by copyright. All rights reserved. presence of PMA-activated human neutrophils. A marked increase in vitamin C uptake by choroid plexus cells was observed that was associated with superoxide generation and vitamin C oxidation (bystander effect). Thus, vitamin C can be incorporated by epithelial choroid plexus papilloma cells using the basolateral polarization of SVCT2 and GLUT1. This mechanism may be amplified with neutrophil infiltration (inflammation) of choroid plexus tumors.
What Has Happened to the Bottom of the US Housing Market?

Housing quality has improved dramatically for most low-income households, but they are paying much larger shares of their income for it. Many discussions of the bottom of the market focus on either the rising costs (the 'bad' news) or the rising quality (the 'good' news). Both points of view have some merit. This paper takes a positivist approach to the question: what's happening to the bottom of the housing market. We use a variety of indicators to look at whether the supply of low-cost units has fallen. We then focus on whether this dwindling supply reflects a market failure. If the market for low-income housing is indeed failing, we would observe: relatively high prices per unit of housing services provided by low-quality housing; obstructions to the supply of low-cost housing, which arises largely from filtering; and high vacancy rates. We find evidence of market failure in some markets but not in others. Finally, we focus on one possible source of market failure—excessive regulation—to see whether it is a common thread across those markets that have difficulty producing low-cost housing.
The Effect of Post-Purchased Perceived-Value Towards the Relationship Quality of Hajj and Umra Travel Agencies in Indonesia

Purpose: About 23% of world's population is Muslims, and it is predicted to grow to 35% in the next 20 years. Million of Muslims from all over the world take Hajj and Umra every year, and Indonesia leads the largest Hajj pilgrims in the world. This makes huge demand for Hajj and Umra travel agencies. To date there are 244 licensed Hajj and Umra travel agencies in Indonesia. However, studies on Hajj and Umra travel agencies are scarce. The initial attempt to study Hajj Umra travel agencies only focused on the impact of perceived value on relationship quality. There is a need to build a more comprehensive model on Hajj and Umra travel agencies.The purpose of this study is to build a comprehensive model on Hajj and Umra travel agencies and to test the model on empirical data. This study attempted to build models from various studies on general travel agencies, with key variables of relationship quality, satisfaction, word-of-mouth, and loyalty.Design/methodology approach: This study uses quantitative design with cross sectional data collection, and convenient sampling will be used to select respondents who already use the service of Hajj and Umra travel agencies in Jabodetabek. Respondents filled structured questionnaires. Data will be analyzed with structural equation modeling. Findings: The findings are to be announced. The data collection is ongoing, and analyses are on pilot-test stage, testing the reliability and validity of the measurements as well as the wordings.Research Limitations: The study limits to travel agencies only and does not employ Hajj and Umra tour packages into the model. The study also has limited population.Practical implications: Results of this study will be beneficial to travel agencies by offering insights to factors that drive satisfaction, loyalty, and word-of-mouth in Hajj and Umra travel agenctes.Originality/value: The study extends the understanding of consumers on religious tourism, in particular Hajj and Umra travel agencies by building and empirically testing a comprehensive model on Hajj and Umra travel agencies.
Prostaglandins and Other Lipid Mediators eview ascular actions of 20-HETE amantha

20-hydroxyeicosatetraenoic acid (20-HETE) is a metabolite of arachidonic acid that exhibits a myriad of biological effects in the vascular system. This review discusses the current knowledge related to the effects of 20-HETE on vascular reactivity, activation, and remodeling, as well as its role in vascular inflammation and angiogenesis. The information explaining how 20-HETE and the renin-angiotensin system interact to promote hypertension, vasoconstriction, and vascular dysfunction is summarized in this arti-