Miracle-dz/UniFAR-FTUs huggingface dataset:
Multi-access services in heterogeneous wireless networks

A variety of wireless interfaces are available for today's mobile user to access Internet content. When coverage areas of these different technologies overlap, a terminal equipped with multiple interfaces can use them simultaneously to improve the performance of its applications. We term the services enabled by such simultaneous use of multiple interfaces as Multi-Access Services. These services constitute Bandwidth Aggregation, Mobility/Reliability Support, Resource Sharing and Data-Control Plane Separation. As a first step towards realizing in practice the above mentioned services, we develop a network layer architecture that introduces minimal changes to the infrastructure. We also identify and implement on an experimental testbed, the various functional components that make up this architecture. While the architecture can support many different services, we explore in depth one such service provided by the architecture: Bandwidth Aggregation (BAG) in the context of Video and TCP applications. For video applications, an important aspect of the architecture when providing BAG services is the scheduling algorithm that partitions the traffic onto different interfaces. We propose one such algorithm Earliest Delivery Path First (EDPF), that ensures packets meet their playback deadlines by scheduling packets based on the estimated delivery time of the packets. We show through analysis, implementation and simulations that EDPF performs close to an idealized Aggregated Single Link (ASL) discipline and outperforms by a large margin other scheduling approaches based on weighted round robin. Apart from the scheduling algorithm, we also consider a content adaptation algorithm, Min Cost Drop (MC-DROP) to selectively drop video frames when adequate bandwidth cannot be reserved on the interfaces. While BAG services can improve the throughput of TCP applications, it introduces challenges in the form of packet reordering. So, we propose Packet Pair based Earliest-Delivery-Path-First for TCP (PET) scheduling algorithm that minimizes reordering by sending packet pairs on the path that introduces the least amount of delay. A Buffer Management Policy (BMP) is also introduced at the client to hide any residual reordering from the TCP receiver. We show through simulations that PET in combination with BMP achieves good bandwidth aggregation under a variety of network conditions.
Impact of serum adipokines on tumor mitotic and apoptotic activity in endometrial cancer

Amac: Endometrial kanser, kadin genital sisteminin en sik gorulen malignitesidir. Obezite, endometrial kanserde en onemli risk faktorlerinden biridir. Adipoz doku, bircok biyoaktif madde salgilayarak tipki bir endokrin organi gibi islev gorur ve tumor gelisimine katkida bulunur. Endometrium kanserinde serum adipokin seviyeleri ile tumor mitotik ve apopitotik aktivite duzeyleri arasindaki iliskinin arastirilmasi amaclanmistir. Yontemler: Kesitsel bir calisma tasarladik. Etik Kurul onayi alindiktan sonra 2014 Temmuz-2014 Aralik tarihleri arasinda Ondokuz Mayis Universitesi Tip Fakultesi Kadin Hastaliklari ve Dogum poliklinigine endometriyal kanserli 38 hasta dahil edildi. Hastalardan preoperatif alinan 5 cc serum orneginde serum leptin ve adiponektin seviyesi olculdu. Hastalarin patoloji spesmenleri immunhistokimyasal calisma ile bcl-2 icin boyanma yuzdesi ve siddeti ve Ki67 icin boyanma yuzdesi gozonune alinarak semikantitatif olarak degerlendirildi. Ayrica hastalarin preoperatif ostradiol seviyesi, insulin direnci, vucut yag oranlari ve body mass index (BMI) degerleri belirlendi. Istatistiksel olarak Mann Whitney U Kruskal Wallis ve Spearman’in Korelasyon testi kullanildi. P 0.05). BMI arttikca serum leptin duzeylerinin istatistiksel anlamli olarak arttigi saptandi (r=0,341, P=0,036). HOMA-IR arttikca adiponektin duzeyi istatistiksel anlamli olarak artmaktaydi (r=0,393, P=0,015). Endometrioid ve non-endometrioid gruplar arasinda da; leptin, adiponektin ve leptin/adiponektin duzeyleri yonunden istatistiksel olarak anlamli farklilik gorulmedi (P=0,554, P=0,652). Endometrioid ve non-endometrioid gruplari arasinda medyan BCL-2 skoru ve Ki-67 yuzdesi yonunden istatistiksel olarak anlamli farklilik gorulmedi (P=0,05). Sonuc: Serum leptin ve adiponektin duzeyi ile tumoral dokuda Ki-67 immunhistokimyasal boyanma yuzdesi ve bcl-2 skoru arasinda istatistiksel anlamli korelasyon yoktur.
Two Cases of KNQ2 Encephalopathy with Unusual Findings: Clinical and Neurophysiological Follow-Up

Introduction: KCNQ2 encephalopathy is a developmental encephalopathy characterized by neonatal-onset pharmacoresistant epilepsy with good response to sodium channel blockers, severely abnormal background EEG activity, and severe developmental delay. In spite of confirmation of this consistent and typical electro clinical syndrome, a broader spectrum of findings has been described. Methods: We report our experience with two cases of genetically-confirmed KCNQ2 encephalopathy. Results: Our two patients, followed-up for 2 and 9 years respectively, show typical clinical and neuroimaging findings, although some peculiarities can be recognized: The first cases developed a Rett-like neurodevelopmental phenotype, while the second patient (already described) had a neonatal ictal EEG reminiscent of epilepsy of infancy with migrating focal seizures and molecular analysis showed a pathogenic de novo deletion, which is an extremely rare finding in KCNQ2 encephalopathy. Conclusions: Our cases further delineate the electroclinical and genetic heterogeneity in patients with KCNQ2 encephalopathy. Additional insights can be expected from the widespread availability of genetic testing in clinical practice.
The alumni narrative of the connection between university skills and knowledge, and industry: An ‘outside-in’ understanding

This study takes an ‘outside-in’ approach by exploring the narratives of university alumni working in industry. The aim of the study is to understand how engaging with industry alumni supports and informs graduate skills and knowledge needed for future employability, and university career/future focused curriculum design. To achieve the aim, the study adopted an Appreciative Inquiry approach to guide a series of n=8 depth interviews recorded in a digital video format. This approach provided alumni with a platform to construct their unique professional narratives in a manner that was relatable and engaging to students, and that universities could use as an educational tool. Data from the interviews resulted in three main themes: 1) the necessity of soft-skills and work experience, 2) the importance of resilience, and 3) the willingness to constantly learn. Theoretically, the findings contribute externally validated support and extension of important and desirable graduate attributes, providing evidence for informing and extending career/future focused curriculum design. Practically, the findings provide students and universities with professional confirmation and foresight of the skills and knowledge needed to transition and navigate the professional workforce, along with an educational tool to implement into curriculum.
Assessment and prevalence of depression among cardiovascular disease patients in Nilgiris District observational cross-sectional study

Depression deter mental catabolic effect over the time, symptomatically affects quality of life which leads to worse health outcomes that linked to higher mortality and morbidity rates with huge impact on public health. Chronic conditions like Cardio Vascular Diseases (CVDs) deteriorates patient health with cognitive impairment that progresses to somatic dysfunction, which can exacerbate to the occurrence and development of depression with the increased risk of inducing Chronic Diseases. Depression are often neglected, overlooked and remains unrecognized and undertreated in the patient, especially in CVDs patient are considered as normal that instances to poor prognosis. The association of depression and CVDs are not incidental, but the lack of diagnosis for the coexistence of these co-morbid condition and poor treatment hindrance the disease outcome. Depression emerges an alarming cardio vascular risk factor which is associated with higher cost of care for the patient as well as burden to the healthcare system. Prior detection and identification with rational intervention of depression at CVDs will help to change the scenario by improving the standard of health and overall quality of life of patient. Here, in this study we assess the prevalence of depression at cardio vascular disease patient in Nilgiris population.
Respiratory effect associated with use of occlusal orthotics in temporomandibular disorder patients

Occlusal orthotics are widely used to manage temporomandibular disorder (TMD). However, the respiratory effects of the use of occlusal orthotics in TMD patients are unclear. The primary purpose of this study was to determine the effect of increased the vertical dimension by an orthotic on the apnea hypopnea index (AHI) and oxygen desaturation index (ODI) of TMD patients. The secondary purpose was to determine whether these effects differed between maxillary and mandibular orthotics. A total of 26 participants who were diagnosed TMD were recruited for this study. The orthotic group performed the Nox-T3 monitor test to obtain the AHI and the ODI, one night without the use of an orthotic(baseline)and the other night two weeks after they began using an orthotic(follow-up). The control group performed the Nox-T3 monitor test for two nights without the use of an orthotic. The AHI and ODI were compared between the baseline and follow-up. In the orthotic group, half of the patients were randomly allocated to the maxillary orthotic group; the other half were allocated to the mandibular orthotic group. The AHI and ODI were compared between maxillary and mandibular orthotic groups. patients reduced respiratory disturbances in non-supine and supine positions.
Organizations In Theory And Practice

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Inventários biológicos rápidos de morcegos (Mammalia, Chiroptera) em três unidades de conservação do Amapá, Brasil

With a high biological diversity and good status of preservation, the northern part of the Amazon Basin, and specially the State of Amapa, have their fauna and flora poorly studied. Studies pointed that Amapa has several areas classified as highest priority for faunal inventories in the Amazon Basin, but even that few studies have been conducted. In order to fulfill part of these knowledge gaps, three of the most important conservation units in the State, namely the Tumucumaque Mountains National Park, the Amapa National Forest and the Rio Iratapuru Sustainable Development Reserve, were studied for different biological groups. The results of four bat surveys in these conservation units are presented here. With a sampling effort of 1730.5 mistnet.hours, 858 bats were recorded, belonging to 51 species, 36 genus and six families. At least 25 of these species are first records for the State, elevating to 73 the number of bat species already recorded in Amapa.
Fear of Falls, Physical Performance and Physical Activity Levels among Older Adults with Falls and Recurrent Falls

Older adults who fall recurrently have sub-optimal physical performance especially muscle strength, mobility and balance. Recurrent falls lead to a heightened fear of falls. However, there is limited information regarding other domains of physical performance, namely, flexibility and endurance. In addition there is still limited knowledge pertaining fear of falls and physical activity levels among Malaysian community-dwelling older adults who are recurrent fallers. The aim of our study was to compare fear of falls, physical performance and physical activity levels among older adults with falls and recurrent falls . This cross- sectional study was carried out in two Malaysian urban districts. Physical performance was examined using Functional Fitness MOT (FFMOT). Modified Baecke Questionnaire and Activities-Specific Balance Confidence (ABC-6) Scale were administered to evaluate the level of daily physical activity and fear of falls respectively. A total 35 older adults participated in this study, 20 fallers (mean age :71.95±8.22) and 15 recurrent fallers (mean age: 76.73±8.82) respectively. Our study results showed that older adults with recurrent fallers had significantly reduced lower extremity strength, dynamic balance, endurance, balance confidence in ADL and physical activity levels compared to faller group (p<0.05). Although flexibility and upper limb strength were not significantly different among fallers and recurrent fallers, overall improvement in physical performance should be targetted in falls prevention and management. This is vital to prevent further deterioration in physical performance among older adults with recurrent falls. DOI : http://dx.doi. org. /10.17576/JSKM-2019-1702-09
Association of Traffic-Related Air Pollution (TRAP) with DNA Damage and Respiratory Health Symptoms among Primary School Children in Selangor

Exposure to Traffic-Related Air Pollution (TRAP) is a public health concern accountable for several health problems each year in Malaysia. Several studies globally have shown that children in schools near high traffic roads have increased risks for Deoxyribonucleic Acid (DNA) damage due to higher exposure to TRAP. The study aimed to determine the association between TRAP exposure with DNA damage and respiratory symptoms among school children in Selangor state. PM2.5, PM10, Ultrafine Particle (UFP), Carbon Monoxide (CO), Carbon Dioxide (CO2), Nitrogen Dioxide (NO2) and Sulphur Dioxide (SO2) were measured as TRAP. A cross-sectional comparative study was carried out among children in Kajang as exposed group (n=52) and Hulu Langat as comparative group (n=52). A set of standardized and validated questionnaires were used to determine respiratory symptoms and history of exposure. Measurements of indoor and outdoor air pollutants were conducted in schools. Buccal mucosa cells were collected, which then followed by investigation of DNA damage using a comet assay. All pollutants were significantly associated with reported cough and wheezing at p<0.05. Meanwhile, PM2.5, PM10 and UFP were significantly associated with comet tail length at p<0.05. Additionally, comet tail length in the exposed group was significantly higher (35.95±7.93 μm) than those in the comparative group (30.32±8.358 μm), and the difference was significantly different (t=3.450, p=0.001). Children were more likely to have genotoxicity of buccal mucosa if they were exposed to higher levels of ultrafine particles (UFP). This study demonstrated that children in schools near heavy traffic roads have an increased risk for respiratory symptoms and DNA damage due to higher exposure to TRAP. Therefore, this study supports its importance as a risk factor in associations documented between TRAP and respiratory health among children.
Prognostic Factors in Patients with Locally Advanced Breast Cancer Treated by Neoadjuvant Chemotherapy

Purpose: Neoadjuvant chemotherapy (NAC) has become the standard treatment for patients with locally advanced breast cancer. The purpose of this study was to evaluate prognosis according to molecular subtype and clinicopathologic factors in patients with locally advanced breast cancer treated by NAC. Methods: We retrospectively analyzed the medical records of 91 patients with breast cancer who underwent NAC followed by surgery between January 2005 and January 2010. The patients were classified into four molecular subtype groups: luminal A, luminal B, HER2 enriched, and triple negative (TN). Results: Thirty-five (38%) patients had luminal A, 13 (14%) patients luminal B, 22 (24%) patients HER2 enriched and 21 (21%) patients TN breast cancer. Patients with TN breast cancer tended to be more than 50 years of age and to have a higher histologic grade. There were statistically significant differences according to ypN stage (ypN0 vs. ypN1–3; p=0.019, 5-year disease-free survival [DFS]; p=0.005, 5-year overall survival [OS]) and lymphovascular invasion (LVI) (p=0.003, 5-year DFS; p=0.006, 5-year OS) in the univariate analysis. In the multivariate analysis, LVI was a significant factor in 5-year DFS (odds ratio 2.145, 95% confidence interval 1.064–4.324, p=0.033). There was no significant difference among molecular subtypes in DFS (p=0.161) or OS (p=0.084). Conclusion: LVI was associated with prognosis in patients with locally advanced breast cancer treated by NAC and surgery. However, molecular subtype had no effect on 5-year DFS or OS.
Cardiac Arrhythmia and Blood Pressure Variability in Hemodialysis Patients

Background: end-stage renal disease is a global public health burden bearing high morbidity and mortality, and cardiovascular disease is a major cause of mortality in hemodialysis patients. Objective: the aim of this study is detection of arrhythmia and blood pressure variability in hemodialysis (HD) patients. Patients and Methods: this prospective observational study included 100 chronic renal failure patients on regular HD came to the hemodialysis center of Al-Azhar University Hospital, New Damietta and Kafr Elsheikh General Hospital. The study was carried out over a period of eight month from July 2017 until September 2018. Results: the intradialytic (ID) blood pressure was normal in 38%, ID hypertension was reported in 44% and ID hypotension was reported in 18% of HD patients, also we found that arrhythmia was developed in 84% of HD patients and the prevalence of arrhythmia was VES in 56%, PAC in 50%, SVT in 4%, AF in 8.0%, sinus tachycardia in 26% and sinus bradycardia in 20%. The sympathetic over activity (LF/HF ratio < 1.5) was reported in 38%; and high risk standard deviation of normal-to-normal intervals (SDNN) was reported in 22% and moderate risk in 70.0% while low risk was reported in 8.0% of HD patients. Conclusion: cardiac arrhythmias are common findings in patients with chronic renal failure on regular hemodialysis.
Etiological Classification of Bile Duct Dilatation and Proportion of Each Cause in 1430 Patients

Objective: To investigate the etiology of bile duct dilatation and proportion of each cause. Methods: A retrospective study was performed by classification on clinical data collected from 1430 patients with bile duct dilatation in our hospital from January 2000 to December 2013.nbsp Results: There were 90 patients with congenital bile duct cysts (6.3%) and 1340 with secondary bile duct dilatation (93.7%). In total, 22 categories of causes were identified. Among them, the top five were bile duct stones (n=476, 33.3%), pancreatic head carcinoma (n=179, 12.5%), periampullary carcinoma (n=159, 11.9%), cholangiocarcinoma (n=89, 6.2%), and chronic pancreatitis or pancreatic head cyst (n=80, 5.6%). Conclusion: The causes of bile duct dilatation can be classified into congenital and secondary categories. The former accounted for approximately 6.0% and the latter for approximately 94%. The most common causes were bile duct stones, pancreatic head carcinoma and periampullary carcinoma.
A retrospective study correlating sonographic features of thyroid nodules with fine-needle aspiration cytology in a South African setting

Background Thyroid nodules are prevalent worldwide. Detection rates are increasing because of the use of ultrasonography. Ultrasound has become the first-choice imaging modality in evaluating nodules. The decision to perform an US-guided fine-needle aspiration (FNA) is based on a nodule’s sonographic features. Thus, it is essential to accurately risk stratify thyroid nodules so that they are appropriately referred for FNA. Objectives The aim of this study was to correlate the ultrasound imaging features of thyroid nodules with FNA cytology and surgical histopathology results, and to risk stratify patients using the American Thyroid Association (ATA) classification for each imaging characteristic with the likelihood of the nodule being malignant. Method Retrospective analysis of a thyroid ultrasound database at Chris Hani Baragwanath Academic Hospital, over the period 2015–2017. Frequencies and percentages were used to summarise the data. Univariate logistic regression analyses were used to assess the accuracy of sonographic features in predicting the histologically determined diagnosis for thyroid tumours. Results A total of 113 nodules underwent FNA, of which 104 were diagnostic. The best three ultrasound features that pose a higher risk for malignancy are absent halo, presence of microcalcifications and hypoechoic appearance. No single nodule feature is an absolute indicator for malignancy. There is a high agreement between ATA classification and cytopathology or histology when nodule features are grouped into clusters. Agreement between the ATA classification and cytopathology/histology was 86.7% with a kappa of 0.714. The agreement between the cytopathology FNA results and lobectomy histopathology was 98.8% with a kappa of 0.973. Conclusion This study contributes to the paucity of data available for sub-Saharan Africa and provides reassurance that our results are consistent with international studies. The study confirms that the usage of a thyroid nodule classification system improves characterisation and increases accuracy in detecting thyroid malignancies, thus sparing many patients the morbidity of unnecessary thyroid surgery.
Efficient and practical algorithms for discrete geodesics

Computing exact geodesic distance plays an important role in many graphics applications. Many research studies have been undertaken in this area since the 1980s. However, the existing geodesic algorithms are not practical for large-scale models or time-critical applications. First, the existing algorithms compute exact geodesic in a serial manner due to the lack of a parallel structure. The computation of geodesic on a large-scale model could be very time-consuming. Second, the widely studied single-source all-destination geodesic algorithms are not elegant for all-pair geodesic queries. Thus, the efficiency and practicality of geodesic computation remain a challenge. To tackle these issues, we systematically studied the discrete geodesic problem. My study focuses on all-pairs geodesic distance, geodesic offsets, and parallel geodesic algorithm on modern GPUs. Furthermore, we propose the world’s first intrinsic and parallel Poisson-disk sampling method on surfaces, which is a time-critical application of discrete geodesics. The contributions of this work are listed as follow: First, we study the discrete geodesics on polygonal meshes with a focus on geodesic offsets and all-pairs geodesics. Geodesic offsets on discrete representation is a geodesic distance field in which the input is typically a polyline curve restricted on the piecewise linear mesh. We propose an efficient and exact algorithm to compute the geodesic offsets on triangle meshes by extending the Xin-Wang algorithm of discrete geodesics. We define a new data structure for parallel-source windows, and extend both the ”one angle one split” and the filtering theorem to maintain the windows tree. We also propose an efficient algorithm to approximate the geodesic distance between an arbitrary point pair on the given surface. We compute m sample points on the given mesh using farthest point sampling algorithm, and construct a geodesic triangulation