Miracle-dz/UniFAR-FTUs huggingface dataset:
Repeatability estimates for milk coagulation traits and non-coagulation of milk in Finnish Ayrshire cows

Effects of systematic environmental factors and milk production and quality traits on milk coagulation properties (MCP), and on repeatability of those traits were estimated from 979 milk samples collected once a month over a period of 2 years from 83 Finnish Ayrshire cows. Estimation was based on a multitrait animal model and REML methodology. In addition, persistence of non-coagulation of milk in individual cows, and factors associated with it were established from a sub sample of 24 cows producing non-coagulating (NC) milk at least once. MCP were at their best during the first lactation, at the beginning and at the end of lactation, and during grazing seasons. Variation in MCP with systematic environmental factors was partly due to variation in composition and quality of milk, especially in pH and ln (somatic cell count, SCC). Coefficients of repeatability for milk coagulation time and curd firmness were 0·65 and 0·68. These estimates were of the same magnitude as those for protein content, but were higher than those for daily milk yield, fat content, pH, and SCC. Based on the repeatability estimates for the milk coagulation traits and effects of the environmental factors, cows should be sampled at least three times during a lactation to estimate reliably breeding values for the milk coagulation traits. A total of 10% of the milk samples did not coagulate in 30 min after addition of rennet. Cows that produced NC milk at least once (30% of the cows) could be classified into those that produced NC milk only a few times during a lactation and those that produced NC milk at almost every sampling. Based on logistic regression analyses, peak and mid-lactation, high milk yield, low protein and fat content and high pH increased the risk of non-coagulation of milk.
Measurement of GABA following GABA‐transaminase inhibition by gabaculine: A 1H and 31P NMR spectroscopic study of rat brain in vivo

A selective 1H NMR spin‐echo editing method was used to detect the CCH, of GABA in rat brain in vivo before and after intravenous administration of the highly selective GABA transaminase inhibitor, gabaculine (3‐amino‐2,3‐dihydrobenzoic acid‐HCl; 100 mg/kg, intravenously). The effects of the inhibitor on high energy phosphates and pH, were determined by 31P NMR. GABA levels increased approximately linearly (r = 0.81 to 0.94; P < 0.0005) from 1.9 ± 0.4 μmol/g (pre‐gabaculine; mean ± SD) to between 6 and 8 μmollg after 4 hr at rates of accumulation of 1.1 to 2.9 μmol/hr/g. 1H NMR spectroscopic measurements of cerebral GABA and its rate of turnover offers a new approach in the study of GABA‐mediated processes in vivo.
Somatostatin and somatostatin receptors: implications for neoplastic growth and cancer biology

Somatostatin agonists (SM-As) are capable of achieving durable symptomatic relief and significant clinical responses in certain tumours. Herein, we review the diverse direct and indirect mechanisms of antineoplastic activity elicited by SM-As as well as the hurdles that complicate their use as monotherapies in a broader range of malignancies. Emphasis is placed on recent clinical attempts to neutralise the IGF-mediated survival factor effects in the bone metastasis microenvironment in advanced prostate cancer. The first clinical trials of this ‘anti-survival factor manipulation’ strategy utilised the ability of SM-As to suppress the growth hormone-dependent liver-derived IGF-I bioavailability in combination with other drugs, such as dexamethasone, zolendronate and oestrogens, acting systemically and at the bone metastasis microenvironment. These regimens restored androgen ablation responsiveness in stage D3 prostate cancer patients and successfully produced objective clinical responses while only mild toxicities were observed. Furthermore, we focus on the preclinical experimental data of a targeted SM-A coupled to the super-potent doxorubicin derivative AN-201. The resulting conjugate (AN-238) has shown increased antitumour potency with a favourable toxicity profile. The potential use of novel SM-As as anticancer drugs is discussed in relation to data suggesting other direct and indirect treatment approaches pertaining to the somatostatin system.
Urban Renewal and Sustainable Development in Jamaica: Progress, Challenges and New Directions

The chapter discusses the history and context of urban renewal in Jamaica and shares the country’s integrated model for urban renewal, as well as the lessons learned from over two decades of implementation. As the urban planning landscape evolves there is a call to move in new directions, incorporating concepts which embody the development of human capital. One call is to re-position urban renewal as a public health tool to reduce crime and violence, communicable and non-communicable diseases, especially for the urban poor and urban youth who share a greater burden of Jamaica’s status as a Low/Middle Income Country (LMIC) and Small Island Developing State (SIDS). The call for the paradigm shift from gender-blind to gender-sensitive urban planning is expected to promote policy coherence between commitments to gender mainstreaming and gender equality and urban development modalities. There is also the need for a new governance framework to support the active participation of the average resident in the decision making process for land use management and other aspects of urban renewal to meet the goals of the New Urban Agenda and to realize Vision 2030 Jamaica, making “Jamaica, the place of choice to live, work, raise families and do business�?
Personal and Interpersonal Perceived Control and the Quality of Life of Persons With Severe Mental Illness

Studies have been carried out to explore the impact of sense of control on the outcome of persons with severe mental illness (SMI). However, few studies have compared the differential effects of perceived personal control (control of the self) and perceived interpersonal control (the control of significant others). In the present study, we investigated the relations between perceived personal and perceived interpersonal control and different domains of quality of life (QOL) of persons with SMI. Measures of perceived personal and interpersonal control and QOL were administered to 145 participants with a diagnosis of SMI (schizophrenia, affective disorders, anxiety disorders, personality disorders). The results showed personal control to be positively related to various domains of QOL (β = .28–.31, p < 0.001–0.01) while interpersonal control was negatively related to the physical domain of QOL (β= –.20, p < 0.05). Theoretical, empirical, and clinical implications of the distinction between personal and interpersonal control for persons with SMI are discussed.
Dietary Zinc Intake and Kidney Stone Formation: Evaluation of NHANES III

Aims: We aimed to determine whether there is an association between dietary zinc intake (DZI) and prevalent kidney stone disease defined as self-report of any previous episode of kidney stone. Methods: We examined The Third National Health and Nutrition Examination Survey (NHANES III), a large US population-based cross-sectional study, and used logistic regression analyses to determine the independent association between DZI and prevalent kidney stone disease. Results: A total of 15,444 men and women over 18 years of age were eligible for analysis. Among them, 710 participants reported a history of kidney stones. Stone formers tended to have higher DZI than non-stone formers among NHANES III participants, though this difference did not reach statistical significance (p = 0.1). Multivariate adjusted logistic regression analysis revealed that higher DZI (log transformed) was associated with a significantly increased risk of kidney stone disease (odds ratio, OR = 1.41, 95% confidence interval, CI: 1.10–1.81, p = 0.01). After categorizing zinc intake into three groups, those with highest DZI (>15 mg/day) were also associated with a significantly increased risk of kidney stone disease, compared to those with lower DZI (<7 mg/day; OR = 1.70, 95% CI: 1.13–2.57, p = 0.01). Conclusions: Our study suggests that higher DZI is associated with increased risk of kidney stone disease. Future prospective studies are needed to clarify the causal relationship between zinc intake and kidney stone formation.
Old questions, new tools, and some answers to the mystery of fin regeneration

Pluridisciplinary approaches led to the notion that fin regeneration is an intricate phenomenon involving epithelial–mesenchymal and reciprocal exchanges throughout the process as well as interactions between ray and interray tissue. The establishment of a blastema after fin amputation is the first event leading to the reconstruction of the missing part of the fin. Here, we review our knowledge on the origin of the blastema, its formation and growth, and of the mechanisms that control differentiation and patterning of the regenerate. Our current understanding results from studies of fin regeneration performed in various teleost fish over the past century. We also report the recent breakthroughs that have been made in the past decade with the arrival of a new model, the zebrafish, Danio rerio, which now offers the possibility to combine cytologic, molecular, and genetic analyses and open new perspectives in this field. Developmental Dynamics 226:190–201, 2003. © 2003 Wiley‐Liss, Inc.
Feline respiratory viruses--their prevalence in clinically healthy cats.

The prevalence of feline calicivirus (FGV) and feline viral rhinotracheitis (FVR) virus was assessed in three different groups of clinically healthy domestic cats. The 1500 cats were sampled using single oro-pharyngeal swabs. The rate of isolation for FCV and FVR virus respectively was 8% and 1% in the household pet sample, 24·02% and 1·75% in the cat-show sample and 41·5% and 0·4% in colonies A and B. The differences are discussed in relation to the different carrier states of these viruses and the social habits of the cats in each group. A computer analysis of the cat-show group with regard to age, sex and breed demonstrated a statistically significant, lower infection rate of FCV in (1) neutered animals as compared with entires, (2) older cats compared with 0–1 year old animals and (3) certain age groups in both the Longhaired and Burmese cats as compared with other breeds. Resume. On a evalue la frequence de virus calice felin et de virus rhinotracheite viral felin dans les differents groupes de chats domestiques cliniquement en bonne sante. On a essaye un seul prelevement oropharyngien dans 1500 chats. Le pourcentage d'isolation pour le virus FCV et le virus FVR etait respectivement de 8% te de 1% dans l'echantillon de prelevement du chat domestique, 24,02% et 1,75% dans l'echantillon du chat d'exposition et de 41,5% et de 0,4% dans les colonies A et B. On discute des differences en relation avec les differents etats des porteurs de ces virus et des habitudes sociales des chats dans chaque groupe. Une analyse par machine a calculer electronique du chat d'exposition concernant l'âge, le sexe et la race a demontre un pourcentage statistiquement significatif plus faible d'infection de FCV chez (1) des animaux châtres compares â des animaux non-châtres, (2) des chats plus âges compares a des animaux de 0 a 1 an et (3) des groupes d'une certaine classe chez des chats a poils longs et des chats de Birmanie en comparaison avec d'autres races. Zusammenfassung. Das Vorherrschen von Katzen-Kalizivirus (FCV) und Katzen-virusalen Rhinotracheitis (FVR) Virus wurden in den verschiedenen Gruppen von klinisch gesunden Hauskatzen geschachtzt. Die 1500 Katzen wurden gepruft indem man einem einzigen Mundrach-enabstrich machte. Das Verhaltnis von Isolierung fur FCV und FVR Virus war jeweilig 8% und 1% in der Hauskatzenprobe, 24,02% und 1,75% in der Katzenschauprobe und 41,5% und 0,4% in den Kolonien A und B. Die Unterschiede werden diskutiert in bezug auf den verschiedenen Ubertragungszustand von diesen Viren und den geselligen Angewohnheiten dieser Katzen in jeder Gruppe. Eine Komputeranalyse der Katzenschaugruppe in bezug auf Alter, Geschlecht und Rasse bewies eine statistisch bedeutsame, niederere Infektionsrate an FCV in (1) kastrierten Tieren als der verglichen mit Nichtkastrierten, (2) altere Katzen verglichen mit 0–1 jahrig alten Tieren und (3) gewisse Altersgruppen bei den langhaarig- und Burmesischen Katzen verglichen mit anderen Rassen.
Surf feature extraction in encrypted domain

Signal processing in the encrypted domain has become a hot research topic, which enable signal processing tasks in a secure and privacy-preserving manner. Taken the fact that SURF (Speeded Up Robust Feature) has been widely utilized in various applications into account, SURF feature extraction method in the encrypted domain has been proposed in this paper. Because all steps must be implemented in the encrypted domain, Paillier homomorphic encryption method is adopted. Experimental results demonstrate that the number and location of SURF features extracted from the encrypted data are the same as those from the plaintext data. And the error between the descriptors obtained from the plaintext data and the encrypted data is only 0.0002932%. We also provide security analysis and complexity analysis. The proposed method can be used in the encrypted domain based applications, such as secure image processing and image retrieval.
PENGARUH DIGITAL MARKETING TERHADAP ORGANIZATIONAL PERFORMANCE DENGAN INTELLECTUAL CAPITAL DAN PERCEIVED QUALITY SEBAGAI VARIABEL INTERVENING PADA INDUSTRI HOTEL BINTANG LIMA DI JAWA TIMUR

Pertumbuhan Pariwisata di Indonesia sangat pesat. Keinginan masyarakat untuk berlibur semakin tinggi. Hal ini menciptakan persaingan yang ketat dalam Industri Perhotelan. Khususnya Industri Perhotelan Bintang Lima di Jawa Timur. Penelitian ini memiliki tujuan untuk menganalisa pengaruh dari Digital Marketing (Cost, Incentive Programs, Site design, Interactive), terhadap Organizational Performance pada Industri Perhotelan di Jawa Timur dengan Intellectual Capital (Human Capital, Organizational Capital, Social Capital), dan Perceived Quality (Features, Realiability, Conformance, Durability, Serviceability, Aesthetic) sebagai variable intervening. Penelitian ini dilakukan dengan menyebarkan kuisioner kepada 130 responden karyawan internal Hotel Bintang Lima di Jawa Timur. Teknik analisa yang digunakan adalah teknis analisis kuantitatif dengan metode path analysis.
Alteration of Glutathione Reductase Expression in the Female Reproductive Organs During the Estrous Cycle1

Abstract The enzyme glutathione reductase (GR) recycles oxidized glutathione (GSSG) by converting it to the reduced form (GSH) in an NADPH-dependent manner. A specific antibody raised against recombinant rat GR was used to localize the protein in the female reproductive organs during the estrous cycle in the rat. In the ovary, the strongest reactivity to the antibody was observed in oocytes, followed by granulosa cells, corpus luteum, and interstitial cells. A strongly positive reaction was also observed mainly in the oviduct epithelia, uterine epithelia, and endometrial gland in the reproductive tract. Oviducts contained the highest GR activity. The GR activity of uterus during metestrus was about twice as high as that for other stages of the cycle. The levels of GR proteins in the tissues roughly matched the activities. The expression of the GR mRNA was highest during metestrus. Because GSH is known to increase gamete viability and the efficiency of fertility, GR, which is expressed in these tissues, is predicted to play a pivotal role in the reproduction process as a source of GSH.
When the job is boring: the role of boredom in organizational contexts.

OBJECTIVE The present study investigates the role of boredom within the Job Demands-Resources model. Although empirical evidence suggests that the incidence of boredom at work is widespread, the study of job boredom remains neglected today. PARTICIPANTS Data were collected from 269 mass-retail workers, by means of structured face-to-face interviews. METHODS Results of multiple mediation analyses partially supported our hypotheses. RESULTS Boredom mediates the relationship between transformational leadership, low learning opportunities and general dysphoria, while work engagement mediates the relationship between transformational leadership, low learning opportunities and job satisfaction as well as general dysphoria. CONCLUSIONS Taken together, our results confirm the suitability of conceptualizing boredom within the JD-R model and contribute to the ongoing conceptualization of both the boredom literature and the JD-R literature.
Treatment of Osteoid Osteomas of the Foot: A Review of 100 Cases

Objectives: Osteoid osteoma (OO) is a small, benign, osteogenic bone tumor, with less than 11% of cases located in the feet. We review our experience in OO of the foot bones in order to characterize its prevalence, treatment, and recurrence rate at long term follow up. Methods: The medical records of 100 cases of osteoid osteoma of the foot treated between 1975 and 2009 were reviewed retrospectively. There were 73 male and 27 female patients, with a mean age of 23.4 years (7-61 years). The lesions were located in the talus (n=59), calcaneus (n=14), metatarsal bones (n=9), cuneiform bones (n=5), phalanges (n=4), cuboid (n=4), navicular (n=2) and tarsal bones, not otherwise specified (n=3). None of the patients had received prior percutaneous or surgical treatment for the tumor. Twelve tumors were intra-articular and 88 extraarticular. All patients were taking routine analgesics including anti-inflammatory medications. Results: Treatment consisted of radiofrequency ablation (RFA) in 43 patients, excisional CT-guided trocar biopsy, or percutaneous drill resection (PDR) in 21 patients, intra-lesional curettage in 43 patients, and wide resection alone as well as wide resection with total ankle arthroplasty in one patient each. Adequate follow-up was available for all patients. One patient treated with RFA reported recurrent pain after 2 months and was successfully treated with a second RFA. The overall recurrence rate was 1%; however, it was 2.3% in those patients treated with RFA. No adverse events related to treatment or to the anatomical location were recorded. Conclusion: RFA is a safe and effective alternative to surgical resection of osteoid osteomas of the foot. Caution should be taken when performing this procedure on lesions less than 1 cm from neurovascular structures or in superficial locations, due to risk for soft tissue injury from thermal necrosis.
An integrative typology of relational benefits and costs in social media brand pages

This article focuses on consumer–brand relationships in the social media environment and suggests a typology of the benefits and costs consumers perceive when interacting with social media brand pages. Employing an online questionnaire, quantitative data were collected from 881 followers of popular brand pages on both Facebook and Twitter. Study results indicate that followers of brand pages on Facebook and Twitter perceive “social,” “functional,” “enjoyment,” “special treatment,” “self-enhancement,” “advice,” and “status” benefits. “Privacy concern,” “information overload,” and “ad irritation” are consumers’ perceived costs. As the same seven factors of relational benefits and three factors of relational costs have been confirmed across all Facebook and Twitter brand pages, it is argued that the structure and dimensions of relational benefits and costs are medium and brand invariant, and are perceived in the same way by Facebook and Twitter followers. Considering the rapid development of social media and their penetration in business marketing actions, this research contributes to the digital marketing literature by providing a better understanding of relational benefits, relational costs, and consumer–brand relationships in a social media context. Finally, the article offers recommendations to brand managers, when designing appropriate social media content, that can enhance and strengthen a brand’s relationship with its customers.
The Bony Obliteration Tympanoplasty in Pediatric Cholesteatoma: Long-term Safety and Hygienic Results

Objective: To present the safety and hygienic results of a 5-year longitudinal study in a pediatric population undergoing surgery for extensive cholesteatoma using a canal wall up approach with bony obliteration of the mastoid and epitympanic space. Study Design: Retrospective consecutive study. Patients: Thirty-three children (⩽18 yr) undergoing surgery for cholesteatoma (34 ears) between 1997 and 2009. Interventions: Therapeutic. Setting: Tertiary referral center. Main Outcome Measures: 1) Residual and recurrent cholesteatoma rates at 5-year postsurgery, 2) postoperative waterproofing and hygienic status of the ear, and 3) required operation rate to achieve the safety and hygienic goals. Results: At 5 years no patients were lost in follow-up. This consecutive series design is rare in chronical otitis media treatment reporting. The standard residual rate at 5 years was 5.8%, representing two residual cholesteatomas in the middle ear. The standard recurrence rate at 5 years was 2.9%, representing one recurrent cholesteatoma. At 5-year follow-up all ears were free of otorrhea and waterproof and all external ear canals were patent and self-cleaning. The operation rate to reach this safety and hygienic status was 1.5 operations per ear at 5-year follow-up. Conclusion: The use of a canal wall up approach with obliteration of the mastoid cavity and epitympanic space to surgically treat cholesteatoma in children results in low residual and recurrence rates and a high rate of trouble-free ears in the long term.
Disclosure and Banking Sector: A Review on the Relationship between Disclosure Governance and Financial Stability

We survey the literature regarding the relationship of disclosure and financial stability for both depositors and financial market participants. We identified in the literature different results which are favorable to the implementation of controlled disclosure policy for banks in order to maintain financial stability. We address the importance of disclosure, emphasizing decisions taken by regulators over recent decades.
REPORTING DESIGN – A SYSTEMATIC LITERATURE REVIEW

Due to the fact, that the quality of decisions is directly linked to the availability and the perception of information, its selection and representation are of major importance in business communication. The purpose of this paper is to identify the current status quo of existing research in the field of information design in business reports (reporting design) in order to cluster empirical contributions and to generate new findings. A systematic literature review consisting of 48 international studies published between 2003 and 2013 was conducted. The extended cognitive fit model from Shaft and Vessey (2006) serves as a research framework. The analysis of its four main perspectives: “External Problem Representation”, “Internal Problem Representation”, “Problem-Solving Task” and “Mental Representation” revealed the following eight literature streams: (1) Tables versus Graphs, (2) Analyses of annual reports, (3) Reporting Guidelines, (4) Knowledge and Skills, (5) Task Type, (6) Task Complexity, (7) Working Memory and Memory Affection, and (8) Information Overload. Based on this literature review a research agenda was developed.