Miracle-dz/UniFAR-FTUs huggingface dataset:
The prognostic value of conventional imaging tools to determine how patients with hodgkin lymphoma will respond to treatment

Article type Systematic review article Introduction: This systematic review studies the prognostic value of two conventional imaging tools, sestamibi and gallium scans, for predicting how patients with Hodgkin lymphoma will respond to treatment. Methods: The PubMed database was searched for English-language articles that contained the following search terms: (Hodgkin AND (mibi OR sestamibi OR gallium OR spect) AND response). All articles that were identified during this search were included in the study, regardless of date published. The inclusion criteria were as follows: articles that described studies that were limited to Hodgkin patients and that reported the predictive value of conventional imaging tools. Articles about other types of lymphoma and/or those that focused on the diagnostic and staging accuracy of mibi and gallium scans were excluded. Result: In total, 14 articles were retrieved. Of these, the majority met the inclusion criteria of the systematic review with the exception of two, which were limited to an examination of the reliability of performing sestamibi scans to predict the response to treatment. All remaining 12 articles considered both the sestamibi scans and the gallium scintigraphy. The results of the systematic review indicate that positive gallium scan results can be proposed as a poor prognostic factor that is associated with partial or full recurrence of Hodgkin disease, a reduction in overall survival rate, and progression-free survival compared with patients with a negative scan. Discussion: Both sestamibi and gallium scans revealed high sensitivity and specificity in predicting the response to treatment including complete remission, partial remission, and recurrence of the disease. Conclusion:These imaging tools can appropriately assess how Hodgkin patients will respond to chemotherapy. As such, clinicians can use these tools to devise appropriate treatment strategies.
Beden Eğitimi Öğretmen Adaylarının Öz Yeterlik Algıları İle Mesleki Kaygıları Arasındaki İlişki

This study aims at comparing the preservice physical education teachers? self efficacy beliefs and professional concern levels 347 PE teachers candidate 130 women and 217 men accepted to participate voluntarily in the study Data were collected through Teachers? Sense of Efficacy Scale TSES developed by Tschannen Moran and Hoy and adapted into Turkish by Capa Cakiroglu and Sarikaya and Concern Scale for Physical Education Teachers developed by McCormack 1996 and adapted into Turkish by Ozer Şad Acak and Kafkas According to the findings of the study subjects? self efficacy levels differed significantly by gender doing sports with a license and type of high school Moreover a moderate level of correlation was found between self efficacy and professional concern levels
Personality Traits and Excessive Computer and Internet Usage: A Robust Relation?

Previous studies on the association between personality traits and computer and/or internet addiction reported mixed results. Moreover, whereas some authors claim that personality traits measures have adequate level of convergent validity (Hong et al., 2008; Paunonen, 2003), recent meta-analysis seems to seriously question it (Pace & Brannick, 2010). The aim of the present study was to examine whether personality traits can reliably predict excessive computer and internet usage in a consistent way and irrespectively of the personality traits measure used. Two hundred and thirty university students voluntarily participated in the study. They provided responses to various instruments including the Big Five Inventory, the International Personality Item Pool, the Computer Addiction Test and Internet usage. Canonical correlation analysis was used to examine the similarity between the two personality traits measures. Results showed that there is 50% of unexplained variance between the two personality measures. Multiple regression analyses (linear or ordinal depending on the nature of the criterion variable) showed that the pattern and strength of predictions seems to fluctuate in relation to the personality traits instrument used. In most cases conscientiousness and agreeableness were revealed as important personality traits to understand technological addictive behaviors. Researchers should be aware of the possible fluctuations in findings when they study the effect of personality traits on computer and excessive internet use.
Undercover fear of elderly people in nursing homes: Death anxiety and depression

Aim: To find out the level of death anxiety and depression level among Turkish elderly people. Methods: This research was carried out on 106 elderly people aged 60 years and older from three different nursing homes. Descriptive statistics, one-way ANOVA, t-test, Cronbach’s alpha coefficient, and correlations were used for the analyses. Results: The 25.4% of elderly were between 65-69 years old, and included most of the elderly who were male (83%), single (92.5%) and retired (35.8%). The overall mean on depression was 14.43, and the death anxiety was 7.57. Mild depression was found in 69.8%, and no symptoms of depression were reported by 16% of the subjects. A positive correlation was found between total score of GDS and TDAS (r: 0.304, p<0.01). Conclusion: Healthcare professionals working with elderly people in nursing homes should be aware about death anxiety of the elderly.
Anemia, Blood Transfusion, and Erythropoietin in the Critically Ill

Critically ill patients receive an extraordinarily large number of blood transfusions. Between 40% and 50% of all patients admitted to intensive care units (ICUs) receive at least one red blood cell (RBC) unit and average close to five RBC units during their ICU admission. For the critically ill patient, the risk of a blood transfusion-transmitted infection is not the major concern. What is of more consequence is the accumulating evidence that blood transfusion has profound negative effects on the immune system. On the other hand, there is little evidence that “routine” transfusion of stored allogeneic RBCs is beneficial to critically ill patients. It is clear that most critically ill patients can tolerate hemoglobin levels as low as 7 mg/dL, and therefore a more conservative approach to RBC transfusion is warranted. The anemia of critical illness is a distinct clinical entity characterized by a blunted erythopoietin (EPO) production and abnormalities in iron metabolism identical to what is commonly referred to as the anemia of chronic disease. As such, the bone marrow in many of these patients responds to the administration of exogenous EPO, in spite of their critical illness. The efficacy of perioperative recombinant human EPO (rHuEPO) has been demonstrated in a variety of elective surgical settings. Similarly, in critically ill patients with multiple organ failure, r-HuEPO therapy will also stimulate erythropoiesis. In a randomized, placebo-controlled trial, therapy with rHuEPO resulted in a significant reduction in RBC transfusions. Despite receiving fewer RBC transfusions, patients in the rHuEPO group had a significantly greater increase in hematocrit.
Neurons' death and rebirth in sparse heterogeneous inhibitory networks

Inhibition is a key aspect of neural dynamics playing a fundamental role for the emergence of neural rhythms and the implementation of various information coding strategies. Inhibitory populations are present in several brain structures and the comprehension of their dynamics is strategical for the understanding of neural processing. In this paper, we discuss a general mechanism present in pulse-coupled heterogeneous inhibitory networks: inhibition can induce not only suppression of the neural activity, as expected, but it can also promote neural reactivation. In particular, for globally coupled systems, the number of firing neurons monotonically reduces upon increasing the strength of inhibition (neurons’ death). The introduction of a sparse connectivity in the network is able to reverse the action of inhibition, i.e. a sufficiently strong synaptic strength can surprisingly promote, rather than depress, the activity of the neurons (neurons’ rebirth). Specifically, for small synaptic strengths, one observes an asynchronous activity of nearly independent supra-threshold neurons. By increasing the inhibition, a transition occurs towards a regime where the neurons are all effectively sub-threshold and their irregular firing is driven by current fluctuations. We explain this transition from a mean-driven to a fluctuation-driven regime by deriving an analytic mean field approach able to provide the fraction of active neurons together with the first two moments of the firing time distribution. We show that, by varying the synaptic time scale, the mechanism underlying the reported phenomenon remains unchanged. However, for sufficiently slow synapses the effect becomes dramatic. For small synaptic coupling the fraction of active neurons is frozen over long times and their firing activity is perfectly regular. For larger inhibition the active neurons display an irregular bursting behaviour induced by the emergence of correlations in the current fluctuations. In this latter regime the model gives predictions consistent with experimental findings for a specific class of neurons, namely the medium spiny neurons in the striatum.
Angiotensin Receptor Neprilysin Inhibitor for Functional Mitral Regurgitation: PRIME Study

Background: The morbidity and mortality of patients with functional mitral regurgitation (MR) remain high, but no pharmacological therapy has been proven effective. The hypothesis of this study was that sacubitril/valsartan would be superior to valsartan alone in improving functional MR via dual inhibition of the renin-angiotensin system and neprilysin. Methods: In this double-blind trial, we randomly assigned 118 patients with heart failure with chronic functional MR secondary to left ventricular (LV) dysfunction to receive either sacubitril/valsartan or valsartan, in addition to standard medical therapy for heart failure. The primary end point was the change in effective regurgitant orifice area of functional MR from baseline to the 12-month follow-up. Secondary end points included changes in regurgitant volume, LV end-systolic volume, LV end-diastolic volume, and incomplete mitral leaflet closure area. Results: The decrease in effective regurgitant orifice area was significantly greater in the sacubitril/valsartan group than in the valsartan group (–0.058±0.095 versus –0.018±0.105 cm2; P=0.032) in an intention-to-treat analysis including 117 (99%) patients. Regurgitant volume was also significantly decreased in the sacubitril/valsartan group in comparison with the valsartan group (mean difference, –7.3 mL; 95% CI, –12.6 to –1.9; P=0.009). There were no significant between-group differences regarding the changes in incomplete mitral leaflet closure area and LV volumes, with the exception of LV end-diastolic volume index (P=0.044). We noted no significant difference in the change of blood pressure between the treatment groups, and 7 patients (12%) in the sacubitril/valsartan group and 9 (16%) in the valsartan group had ≥1 serious adverse events (P=0.54). Conclusions: Among patients with secondary functional MR, sacubitril/valsartan reduced MR to a greater extent than did valsartan. Our findings suggest that an angiotensin receptor-neprilysin inhibitor might be considered for optimal medical therapy of patients with heart failure and functional MR. Clinical Trial Registration: URL: https://www.clinicaltrials. gov. Unique identifier: NCT02687932.
Socioeconomic Characteristics, Oral Care Habits and Oral Health-Related Quality of Life among the Parents of Pre-School Children in Klaipėda

Abstract There is a lack of data about oral health-related quality of life (OHRQoL) among the parents of pre-school children, especially in Lithuania and the relationships among socio-economic status, oral care habits and OHRQoL. Research questions: is OHRQoL influenced by socioeconomic status or oral care habits? Research focus – oral health-related quality of life among the parents of pre-school children. The aim of this study was to analyze the relationships among socioeconomic status, oral care habits and oral helath-related quality of life among the parents of pre-school children in Klaipeda. The study sample consisted of 375 parents (mother or father) of pre-school children. The questionnaire survey was conducted at randomly selected 23 kindergartens in Klaipeda city. The questionnaire consisted of sociodemographic and oral care habits questions. All the participants were examined by self-administered OIDP questionnaire, which measured oral impacts on physical, psychological and social aspects of daily performances. The highest overall impact on OHRQoL among the parents of pre-school children was observed in the domain of Carrying out major work or role (73.0), the lowest one in the Eating and enjoying food (25.74) domain. Mean OIDP score was significantly higher among the parents whose socioeconomic status was low (35.44), reflecting poorer OHRQoL, as compared with high (8.07) socioeconomic status. Parents with poor oral care habits significantly more frequently were affected (79.2%) in Smiling, laughing domain, as compared to the parents whose oral care habits were good (20.8%). Lower socioeconomic status and poorer oral care habits were related with worsened oral health-related quality of life, especially in the area of psychological performances.
Understanding the Career Aspirations of Diverse Community College Students

The purpose of the study was to examine the relative contributions of career predictors (self-efficacy, career barriers, and coping-efficacy for overcoming barriers) in predicting educational and achievement aspirations in a diverse sample of community college students. Data from 236 community college students were utilized. Results from hierarchical regressions suggested that career-decision self-efficacy, college self-efficacy, compromising career for partner, perceptions of barriers, and coping efficacy in overcoming barriers were unique predictors of achievement and educational aspirations. As hypothesized, coping efficacy accounted for variance above and beyond the contributions of self-efficacy and barriers in predicting aspirations. Implications of these findings for research and practice are discussed.
Everyday resilience, reworking, and resistance in North Jakarta’s kampungs

In the kampungs of North Jakarta, people make their lives in the face of a variety of transformations. While Jakarta has always experienced flooding from the coast and from its rivers, flooding is getting worse, and has dramatic effects on kampungs and their residents. At the same time, flood mitigation efforts by the government of Jakarta involve new infrastructures, such as sea walls and land reclamation, which interrupt livelihood practices in the kampungs and have led to violent evictions. Residents of North Jakarta’s kampungs must negotiate the surprise impacts of both flooding and the government’s attempts to manage flooding. In this article, we catalogue the social and material practices that support life and livelihoods in the contexts of these urban environmental transformations, drawing from fieldwork conducted in three North Jakarta kampungs and from recent critical geographical research about urban resilience and urban political ecologies. We describe these practices as everyday acts of resilience, reworking, and resistance. These everyday practices are social and material, drawing from and remaking social and material relations. Although everyday practices of resilience, reworking, and resistance require investments in social relations, we also demonstrate that the dividends filter through existing power structures in the kampungs.
Emerging multikinase inhibitors for the treatment of differentiated thyroid cancer: whom to treat?

Thyroid cancer (TC) is the most common endocrine malignancy, showing a rapid growth in its incidence during recent years. In 2013 the predicted number of all people with TC living in the USA was nearly 637,000, whereas estimated number of new cases diagnosed in 2016 is about 64,300. TC accounts for ~3.8% of all new cancer cases, but—due to a generally good prognosis—in 2016 this disease will count for no more than 2000 deaths (0.3% of all cancer mortality) (1).
MODELING THE INFLUENCE OF ATTRACTIVE PETROLEUM FISCAL REGIME DIMENSIONS ON MARGINAL FIELDS’ INVESTMENT CLIMATE IN MALAYSIA

Attractiveness of a country petroleum fiscal system plays significant role in investment location decisions. This study modeled the influence of attractive petroleum fiscal regime dimensions on marginal oil fields’ (MOFs) investment climate in Malaysia. The dimensions examined in this study are fiscal administration/economy, fiscal certainty, fiscal efficiency, and fiscal equity/neutrality. Data was collected through survey of accounting, business and taxation experts’ within Malaysian MOFs subsector. It was analyzed using Partial Lease Square (PLS) – Structural Equation Modeling (SEM) version 3 and Special Package for Social Science (SPSS) version 19. The results showed that fiscal certainty, fiscal efficiency and fiscal equity/neutrality were found to have significant positive influence on marginal oil fields’ investment climate, adversely insignificant influence of fiscal administration/economy on marginal oil fields investment climate was reported. The result has established weaker link between petroleum fiscal regime administration and MOFs’ investment climate in Malaysia, thus highlighting the scope for improvement on this dimension. Therefore, it is recommended that concerned authorities should consider strengthening of the administrative framework of MOFs’ fiscal regime, thereby enhancing its investment climate. To the best of our knowledge this is the first study that employed the use of experts’ perception in modeling the influence of attractive fiscal regime dimensions on oil and gas fields’ investment climate, and eventually investment location decisions.
Digital photogrammetric mapping of canopy height in a radiata pine plantation

Tree height is a crucial stand characteristic in forest inventories and has been used widely to estimate timber volume, to monitor growth rate, and as an indicator of site quality. Current tree heighting relies on field measurements, with sampling rates, which are typically less than one percent. Low sampling rates produce high variation in measured parameters and reduce statistical reliability. Digital photogrammetry provides an opportunity to automate the measurement of tree heights and to generate digital models of forest canopies. A sufficiently dense canopy model, with tree height data at nearly 100% sampling rates, has the potential to improve significantly the reliability of strategic and operational forest inventory. This study investigates the utility of digital photogrammetric techniques to map tree height within radiata pine plantations. A digital photogrammetric workstation, the Leica Helava DPW 770, was used to generate digital canopy models of both closed canopy and thinned stands. The performance of the image-matching algorithm was assessed using scanned aerial photos of different film types and scales, including colour, black and white, colour infrared, and black and white infrared, at 1:5,000, 1:10,000, and 1:15,090 scales. Canopy height data were obtained by subtracting a DTM from the photogrammetric data. Various filtering strategies were used to process the canopy height data including median, mean tallest tree, adaptive wavelet, adaptive Fourier filtering, and NDVI-thresholding techniques. A method for improving automatically derived tree height using a limited number of manually measured tree heights using a DPW was also developed. The reliability of the derived data was assessed by comparing it with a reference DCM produced using an analytical stereoplotter at a lOm grid, and field measurements. The study demonstrates that tree heights in a coniferous forest can be mapped using digital photogrammetric methods and appropriate post-processing. Filtered digital photogrammetric data are shown comparable to analytical stereoplotter data and field-measured data, particularly for dense stand. With the efficiency and high sampling rates afforded by digital photogrammetric techniques, this study demonstrates the potential application of photogrammetrically measured tree height data to forest inventory.
L'apparition des sensilles styloconiques sur la trompe au cours de l'évolution des Lépidoptères: les pièces buccales d'Apoplania valdiviana Davis & Nielsen 1984 (Glossata: Neopseustoidea: Neopseustidae)

Les pieces buccales du papillon sud-americain, Apoplania valdiviana (Neopseustidae) ont ete etudiees a l'aide du microscope electromque a balayage. Le labre est triangulaire ; les mandibules sont presentes mais reduites, non articulees et legerement sclerifiees. Les palpes maxillaires sont longs et constitues de cinq segments ; le quatrieme et le cinquieme sont les plus longs et de longueur egale. Les galeae maxillaires qui constituent la trompe sont relativement courtes et de longueur presque egale a la moitie de celle des palpes maxillaires. Les palpes labiaux, trisegmentes, sont de longueur egale aux galeae. Les sensilles sont localisees essentiellement sur les galeae et les quatre palpes. Les galeae possedent des sensilles chetiformes sans pore tactiles, des sensilles basiconiques a pore terminal gustatives et des sensilles styloconiques a pore terminal gustatives. Les palpes maxillaires portent des sensilles chetiformes sans pore a fonction tactile et deux groupes (apical et subapical) de sensilles styloconiques a pore terminal gustatives. Au moins une sensille campaniforme constitue l'aire sensorielle basale des palpes labiaux. La cupule sensorielle apicale des palpes labiaux n'a pu etre etudiee. Le caractere le plus original de la trompe d'Apoplania est la presence des sensilles styloconiques a pore terminal sur les galeae. Les Neopseustidae sont la premiere famille a posseder des sensilles styloconiques sur les galeae, au cours de l'evolution des Lepidopteres. Cette decouverte contredit les affirmations de Krenn & Kristensen (2000) qui signalent la premiere apparition des sensilles styloconiques beaucoup plus tard dans l'evolution, avec les Incurvarioidea.
Visual Aids in English Language Teaching : The Practice of Visual Aids in a 'Real-life' Setting

The purpose of my thesis is to illuminate the difference between the use of visual aids in `real-life' schools and practicum schools. It will prove that in practicum schools a large variety of visual aids are applied, while in ordinary schools the blackboard appears to be the ultimate visual aid. Using questionnaires filled in by English language teachers and the observation of some of the same teachers' lessons, I will demonstrate that although `real-life' teachers are aware of the application of different visual aids, they seem to use only the blackboard.