Miracle-dz/UniFAR-FTUs huggingface dataset:
Tapping of Aquatic Plant Nymphaea pubescens WILLD . For Synthesis of Silver Nanoparticles and Its Antimicrobial Evaluation

International Journal of Pharmaceutical Sciences Review and Research Available online at www.globalresearchonline. net © Copyright protected. Unauthorised republication, reproduction, distribution, dissemination and copying of this document in whole or in part is strictly prohibited. © Copyright protected. Unauthorised republication, reproduction, distribution, 63 Koya Siva Prasad*, Nataru Savithramma Department of Botany, Sri Venkateswara University, Tirupati, Andhra Pradesh, India. *Corresponding author’s E-mail: koyasiva1985@gmail.com
Riboswitches and synthetic aptamers : a head-to-head comparison

Nucleic acid aptamers are unique molecular structures used for binding to diverse targets. There is a major challenge in adapting in vitro-selected RNA aptamers for building in vivo RNA devices that control cell function. In contrast, their natural nucleic acid counterparts, riboswitches, were deliberately evolved for efficient gene regulation and cellular programming. Encoded within cells, riboswitches exploit a natural aptamer module to bind to an intracellular small molecule target enabling regulation of fundamental metabolic pathways. Here, we review several key features of natural riboswitches that may account for their function in the cellular environment. We compared these features to those of in vitro selected RNA aptamers that bind to small molecule targets. Our analysis revealed that the aptamer structure and magnesium-dependence might be the largest contributors to failed synthetic RNA devices. Thus, we make several suggestions for forthcoming aptamer selections, which may improve the success of synthetic RNA design, implementation into cells, and ultimately expand their applications.
alcohol advertising , marketing and portrayal on drinking behaviour in young people : systematic review of prospective cohort studies

Background: The effect of alcohol portrayals and advertising on the drinking behaviour of young people is a matter of much debate. We evaluated the relationship between exposure to alcohol advertising, marketing and portrayal on subsequent drinking behaviour in young people by systematic review of cohort (longitudinal) studies. Methods: studies were identified in October 2006 by searches of electronic databases, with no date restriction, supplemented with hand searches of reference lists of retrieved articles. Cohort studies that evaluated exposure to advertising or marketing or alcohol portrayals and drinking at baseline and assessed drinking behaviour at follow-up in young people were selected and reviewed. Results: seven cohort studies that followed up more than 13,000 young people aged 10 to 26 years old were reviewed. The studies evaluated a range of different alcohol advertisement and marketing exposures including print and broadcast media. Two studies measured the hours of TV and music video viewing. All measured drinking behaviour using a variety of outcome measures. Two studies evaluated drinkers and non-drinkers separately. Baseline non-drinkers were significantly more likely to have become a drinker at follow-up with greater exposure to alcohol advertisements. There was little difference in drinking frequency at follow-up in baseline drinkers. In studies that included drinkers and non-drinkers, increased exposure at baseline led to significant increased risk of drinking at follow-up. The strength of the relationship varied between studies but effect sizes were generally modest. All studies controlled for age and gender, however potential confounding factors adjusted for in analyses varied from study to study. Important risk factors such as peer drinking and parental attitudes and behaviour were not adequately accounted for in some studies. Conclusion: data from prospective cohort studies suggest there is an association between exposure to alcohol advertising or promotional activity and subsequent alcohol consumption in young people. Inferences about the modest effect sizes found are limited by the potential influence of residual or unmeasured confounding. Published: 6 February 2009 BMC Public Health 2009, 9:51 doi:10.1186/1471-2458-9-51 Received: 9 January 2008 Accepted: 6 February 2009 This article is available from: http://www.biomedcentral. com/1471-2458/9/51 © 2009 Smith and Foxcroft; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The Role of Bone Growth Stimulating Devices and Orthobiologics in Healing Nonunion Fractures

s presented for the past 2 years at the American Academy of Orthopedic Surgeons (AAOS), the Orthopedic Trauma Association (OTA) and the American Orthopedic Foot and Ankle Society (AOFAS) meetings were reviewed to identify studies relevant to Key Question 6. Studies identified from the supplemental search and the meeting abstracts are discussed in the body of this report, but are not included in the full evidence tables in the Appendices. We used the following criteria to determine which studies would be included in our analysis for Key Question 6: 1. Studies published in English. (A translated study provided to us is discussed to provide additional information on ultrasound technology.) 2. Articles published from 1990 to the present. (Studies of bone growth stimulating devices conducted prior to 1990 which otherwise meet our inclusion criteria are discussed to provide historical context for more recent publications included in the systematic review.) 3. Studies of adult humans. The developmental processes involved in bone growth prior to adulthood lead to additional complexities in the treatment of nonunions which are not relevant in the general Medicare population. We did not exclude studies which included a small number of individuals younger than 18 years of age. 4. Studies using controlled, cohort, and case series designs. Controlled studies are the preferred study design for sorting out the influence of the treatment under study from other potential influences. While we did not identify long-term studies to substantiate the belief that nonunions will not heal without further intervention, there appears to be consensus in the orthopedic community that this is the case. Therefore, carefully designed case series that reduce the potential that other aspects of treatment are responsible for healing may provide valid evidence of device or orthobiologic effectiveness. ECRI proposes a careful evaluation of uncontrolled studies in this systematic review to judge the quality and validity of their results.
Influence of Occupational Stress on Teachers ' Performance in Public Secondary Schools in Nyeri County , Nyeri South Sub County Kenya

The cost of occupational stress has been very high in many organizations. Stress can undermine the achievement of goals, both for individuals and for organizations. Managers are in dilemma over what interventions need to be employed to minimize the cost associated with occupational stress on organizational performance. This study investigated the influence of occupational stress on performance of teachers in Nyeri South Sub-County, Nyeri County. This study employed descriptive survey research design. Data collection was undertaken using questionnaires which were issued to teachers and principals from 12 out of 34 schools. There was a total of 72 respondents, 12 were principals while the rest were other teachers. Stratified random sampling and simple random sampling was used to pick schools and teachers respectively. The data was analyzed using statistical packages for social sciences (SPSS). Descriptive statistics involving frequencies and percentages was used to explain the findings of the study. The study established that the teachers have many activities to carry out in the process of executing their main duty of teaching. These include preparing professional documents including: lesson plan, schemes of work, records of work and student progress record as well as administering, marking and analyzing examinations. In carrying out other duties other than teaching, some respondents indicated that they are not very comfortable, while others indicated that they are comfortable. Regarding interpersonal relationship majority felt that it was good but some indicated that it was bad and very bad in some cases. The study established that most of the resources were adequate or satisfactory but other resources were inadequate in some schools. Most respondents indicated that there were administrative factors that affect teachers negatively. Communication was either good or bad. The study also established that the academic performance of most of the schools in Nyeri south sub –county was average, with a few being above average while the rest were below average. The study specifically recommends that the government should ensure that they are enough teachers in schools to avoid work overload and that the various stakeholders should ensure that there are adequate resources to create a conducive environment. Team building and conflict resolution seminars and workshops should also be held to enhance good interpersonal relationships and those in administration should attend more seminars and workshops concerning administration including the principals, deputy principals and the heads of departments in the schools.
Assessment of Serum Lipid Profile among Sudanese Patients with Malaria

Changes in lipid profile are seen in many patients infected with malaria parasite. The malaria parasite causes hepatocellular damage and disturbs lipid handling by the liver. Inside hepatocytes and erythrocytes the parasite replicates rapidly scavenging cholesterol and lipids required for its growth and metabolism from the host. It also requires host lipids for detoxification of free heme to form the malarial pigment, haemozoin. Aim to Assess Serum lipid profile in patients with malaria in Khartoum state. Material and methods the present study was analytical cross-sectional study carried out during Sep 2016 to Dec 2016, at Khartoum State at alssagai rural hospital. Total of one hundred individuals were enrolled in this study, and classified into two groups 50 patients with malaria as case group and 50 healthy individuals as control group. Result as compared there is difference in HDL, LDL, cholesterol and triglycerides between malaria patients and control subjects (p<0.05). Patients with malaria showed low HDL (20.00 ±3.76mg/dL versus44.52 ± 4.85 mg/dL), low LdL (59.00 ±16.15 mg/dL versus107.76 ±9.76mg/dL), low cholesterol (114.78 ± 16.75mg/dL versus175.34 ± 16.83 mg/dL) and elevated triglycerides (172.4 ± 25.63mg/dL versus135.7 ± 11.66 mg/dL). The observations show a statistically significant. Conclusions malaria infection, both P. vivax and P. falciparum infections, causes derangements in lipid profile that are characterized by low serum, low HDL, low LDL and high triglyceride levels but differ in total cholesterol level . These derangements may be of diagnostic, prognostic or therapeutic value.
SUMMARY: MARANDU GRASS ROOT SYSTEM AS AFFECTED BY THE COMBINATIONS OF NITROGEN AND SULPHUR RATES

Um sistema radicular bem desenvolvido na gramínea forrageira é necessário para a formação e sustentação da planta e, como conseqüência, para a boa produtividade da pastagem. Objetivou-se avaliar características radiculares da Brachiaria brizantha cv. Marandu, em resposta a combinações de doses de N e S na solução nutritiva, empregando sílica como substrato, num experimento realizado em casa de vegetação no período de setembro a dezembro de 2001. Utilizou-se o esquema fatorial 52 fracionado, com 13 combinações de N e S, em mg L-1, respectivamente: 14 e 3,2; 14 e 32; 14 e 80; 126 e 12,8; 126 e 64; 210 e 3,2; 210 e 32; 210 e 80; 336 e 12,8; 336 e 64; 462 e 3,2; 462 e 32 e 462 e 80, as quais foram distribuídas segundo o delineamento de blocos ao acaso, com quatro repetições. Foram realizados dois cortes nas plantas. Após o segundo corte, as raízes foram separadas do substrato e avaliadas. A concentração de N e os acúmulos de N e de S nas raízes do capim mostraram-se dependentes da interação entre as doses de N e S. A dose de N foi determinante para o comprimento, superfície, produção de massa seca, relação comprimento:massa seca e concentração de S no tecido das raízes da forrageira. A produção de massa seca, o comprimento, a superfície das raízes e o acúmulo total de N e de S nas plantas do capim tiveram significativas correlações entre si.
ERIA-DP-2016-36 ERIA Discussion Paper Series The Trade Effect of Border Controls : Evidence from the European Schengen Agreement *

The Schengen Agreement is an important milestone in the European integration process. The purpose is to facilitate the flow of goods, services, and persons across intraEuropean borders. How successful is it in achieving this goal? We apply an econometric gravity analysis to bilateral trade. Unlike earlier analysis, we acknowledge that Schengen treats different country pairs differently, depending on their relative geographical location. Moreover, we find it crucial to carefully control for other elements of European integration such as membership in the customs union, the single market or the currency union, and to factor in countries’ trade with themselves. Schengen has boosted trade by about 2.81% on average, on top of the EU’s trade effects (equivalent to a drop in tariffs between 0.46 and 1.02 percentage points). Trade creation effects for services are stronger than for goods, but estimates feature larger parameter uncertainty. Peripheral countries benefit more than central ones. Other aspects of EU integration matter much more for trade than Schengen.
Assessing the effectiveness of protected area management in the Turkish Caucasus O ğ uz

Despite expected benefits such as conservation, recreation or sustainable development, most protected areas (PAs) have serious problems in implementing basic management functions such as planning, organizing, coordination or control. In order to maximize management effectiveness, the World Wide Fund for Nature (WWF) has developed the rapid assessment and prioritization of protected area management (RAPPAM) methodology for assessment of protected area management at system level based on planning, pressure and threats, inputs, processes and outputs. The RAPPAM assessment was implemented in the Turkish part of the West Lesser Caucasus for 11 PAs with 3 different categories. Two meetings were conducted with the participation of 70 people in possession of the best local knowledge about the PAs in the region. The results show that management assessment scores in all areas were rather low and this finding was similar throughout Turkey. In general, policy environment scores were remarkably below the average, showing that the importance and priority of conservation among public policies is rather low. Threats in the region were high in areas with high biological diversity. Further, semi natural processes, pollution, conversion and tourism appeared to be the greatest threat and pressure elements for the PAs in the region.
Title Threshold Shear Strains for Cyclic Degradation and Cyclic Pore Water Pressure Generation in Two Clays Permalink

Cyclic threshold shear strains are fundamental cyclic soil properties that have not been fully investigated. To learn more about the threshold shear strains for cyclic degradation, γtd, and cyclic pore water pressure generation, γtp, in fully saturated clays, nine multistage cyclic strain-controlled NGI direct simple shear tests are conducted on laboratory-made kaolinite clay (PI 1⁄4 28) and kaolinite-bentonite clay (PI 1⁄4 55). Three levels of vertical effective consolidation stress, σ 0 vc (113 kPa, approximately 216 kPa, and approximately 674 kPa); three OCRs (1, 4 and 7.8); and two cyclic loading frequencies, f (0.01 and 0.1 Hz), were applied. In three tests on the normally consolidated (NC) kaolinite clay, γtd varied between 0.012 and 0.014% and γtp between 0.014 and 0.034%. In two tests on the overconsolidated (OC) kaolinite clay with OCR 1⁄4 4, γtd was 0.013% and γtp 0.016 and 0.017%. In two tests on the NC kaolinite-bentonite clay, γtd was 0.013 and 0.016% and γtp 0.052 and 0.078%. In the test on OC kaolinite-bentonite clay with OCR 1⁄4 4, γtd was 0.014% and with OCR 1⁄4 7.8 it was 0.012%. For the same soil γtp is typically slightly greater than γtd. Clear trends of γtd and γtp with σ 0 vc, OCR, and f could not be identified given the relatively small number of tests. The results indicate that if these trends exist they are small. The comparison of the above results with those from the literature shows that γtd for six different soils ranges between 0.006 and 0.05% and γtp for eight soils between 0.014 and 0.1%, and that there is a modest trend of γtd and moderate trend of γtp increasing with PI. DOI: 10.1061/(ASCE)GT.1943-5606.0001461. © 2016 American Society of Civil Engineers.
CCR 7 Is Recruited to the Immunological Synapse , Acts as Co-stimulatory Molecule and Drives LFA-1 Clustering for Efficient T Cell Adhesion Through ZAP 70

Citation: Laufer JM, Kindinger I, Artinger M, Pauli A and Legler DF (2019) CCR7 Is Recruited to the Immunological Synapse, Acts as Co-stimulatory Molecule and Drives LFA-1 Clustering for Efficient T Cell Adhesion Through ZAP70. Front. Immunol. 9:3115. doi: 10.3389/fimmu.2018. 03115 CCR7 Is Recruited to the Immunological Synapse, Acts as Co-stimulatory Molecule and Drives LFA-1 Clustering for Efficient T Cell Adhesion Through ZAP70
The Effect of Aerobic Training on Tumor Growth , Adiponectin , Leptin and Ghrelin in Mice with Breast Cancer

Background: Breast cancer is widespread in Iran and exercise training is an adjuvant strategy for managing this illness. Objectives: The aim of this study was to investigate the effects of aerobic training on tumor growth and its relationship with changes in adiponectin, leptin, and ghrelin in mice with breast cancer. Materials and Methods: In this animal experimental study, which was conducted during year 2016 in Iran, 20 female BALB/c mice were randomly divided to two groups: Tumor Control (TC) and Exercise (E). The MC4L2 cancer cells were injected in the mice. The E group then performed progressive aerobic training for six weeks. Tumor volume, food intake, weight, and muscle endurance of all mice were measured weekly. At six weeks, the mice were sacrificed and tumor, gastrocnemius muscle, and heart weights were measured. Level of cytokines/hormones were quantified using the Enzyme Linked Immunosorbent Assay (ELISA) methodology in tumor, serum, muscle, and adipose tissue. Results: Aerobic exercise training was associated with a significantly decreased growth rate and final weight of the tumor (1.11 versus 2.74 g) compared to the TC group (P < 0.05). Exercising mice also had greater food intake, muscle endurance, heart weight (0.12 versus 0.09 g), and muscle weight (0.078 versus 0.045 mg) when compared with the TC group (P < 0.05). In addition, the E group had significantly increased adiponectin in all sites except the tumor, decreased leptin in all sites, and increased ghrelin in serum compared to the TC group (P < 0.05). Conclusions: Aerobic exercise training in mice with breast cancer attenuated tumor burden and cachexia, and improved appetite, muscle size and function and fitness relative to non-exercising controls.
Analysis of Second-Term Reenlistment Behavior.

Abstract : This study examines the reenlistment intentions of enlisted personnel in their second term of military service. Data were taken from the DoD Survey of Enlisted Personnel, completed in mid-1979. About 2500 enlistees (from all services) met the working definition of having less than one year remaining in their second term, having served six to ten years, and having achieved a pay grade of E3 through E7. A statistical analysis (logistic regression model) was tailored to each service: it related the survey respondent's reenlistment intentions to four types of factors: compensation, promotion, location, and job satisfaction. Compensation and promotion emerged as the key factors, the others assuming varying degrees of importance in different services. As a reenlistment incentive, however, guaranteed location of choice emerged as potentially important, along with bonuses, shorter reenlistment periods, and increased probability of promotion. (See also R-717, R-2935, R-2152, R-2468). (Author)
Encoder Decoder Conditioning motion Seed motion PredictionPredictor Groundtruth Real or fake ? Discriminator Training : Inference : Encoder Decoder

Teaching a robot to predict and mimic how a human moves or acts in the near future by observing a series of historical human movements is a crucial first step in human-robot interaction and collaboration. In this paper, we instrument a robot with such a prediction ability by leveraging recent deep learning and computer vision techniques. First, our system takes images from the robot camera as input to produce the corresponding human skeleton based on real-time human pose estimation obtained with the OpenPose library. Then, conditioning on this historical sequence, the robot forecasts plausible motion through a motion predictor, generating a corresponding demonstration. Because of a lack of high-level fidelity validation, existing forecasting algorithms suffer from error accumulation and inaccurate prediction. Inspired by generative adversarial networks (GANs), we introduce a global discriminator that examines whether the predicted sequence is smooth and realistic. Our resulting motion GAN model achieves superior prediction performance to state-of-the-art approaches when evaluated on the standard H3.6M dataset. Based on this motion GAN model, the robot demonstrates its ability to replay the predicted motion in a human-like manner when interacting with a person.
Embryonic Development of the Ventral Nervous System of the Stonefly , Kamimuria tibialis ( Pictet )

I have been studying the embryonic development of the stonefly, Kamimuria tibialis to understand the basic developmental pattern of the Plecoptera, and to examine the phylogenetic relationship between the Plecoptera and other polyneopteran orders from the embryological point of view. In our previous papers on the embryogenesis of K. tibialis (Kishimoto and Ando, 1985, 1986), we described the changes in the external features of the embryo and the formation of the alimentary canal, but the embryogenesis of other organs remains unpublished. In the present paper, I describe the embryogenesis of the ventral nervous system of K. tibialis.
Identification and evaluation of regulatory factors modulating the expression of LEE4 in enterohemorrhagic Escherichia coli O157:H7

The locus of enterocyte effacement (LEE) encoded operons (LEEJ LEE5) enable enterohemorrhagic Escherichia coli (EHEC) 0157:H7 to produce attaching and effacing lesions on intestinal cells (A/E). We have previously reported that hha-deleted EHEC 0157:H7 up-regulated LEE4 through increased expression of /er, the regulatory gene encoded by the LEE] operon. In the present study, we demonstrate that a transpositional insertion in clpXP abrogated the increased expression of the LEE4 in the hha-deleted strain. The loss of LEE4 up-regulation in an EHEC 0157:H7 /Jhha, iJclpXP mutant was restored by transposon insertions immediately upstream of grlR of the grlR-grlA operon, suggesting that Names or trade names of commercial products mentioned in this article are solely for the purpose of providing specific information and do not imply recommendation or endorsement by the US. Department of Agriculture.