Miracle-dz/UniFAR-FTUs huggingface dataset:
Análisis experimental de la resistencia al fuego de pilares tubulares circulares de acero esbeltos rellenos de hormigón

En los ultimos tiempos, el empleo de perfiles tubulares de acero rellenos de hormigon ha experimentado un notable incremento debido a su buen comportamiento, por una parte, estructural, al combinar el efecto del hormigon y del acero trabajando conjuntamente, y por otra, en situacion de incendio, al presentar unos elevados tiempos de resistencia al fuego sin necesidad de proteccion externa. Una extensa revision del estado actual del conocimiento ha permitido constatar que, si bien el comportamiento frente al fuego de estos perfiles tubulares de acero rellenos de hormigon ha sido investigado en profundidad en las ultimas decadas, el numero de investigaciones experimentales especificamente disenadas para evaluar la resistencia al fuego de pilares tubulares circulares de acero esbeltos rellenos de hormigon de alta resistencia sometidos a cargas excentricas es escaso. Este trabajo de investigacion analiza una campana experimental consistente en el desarrollo de 40 ensayos de resistencia al fuego sobre pilares tubulares circulares de acero esbeltos rellenos de hormigon, tanto de resistencia normal como de alta resistencia, y sometidos a la accion de cargas centradas y excentricas, con el fin de analizar la influencia de estas variables. Asi, los parametros de diseno de este programa experimental son el valor nominal de la resistencia a compresion del hormigon (30 y 90 MPa), el tipo de hormigon de relleno (en masa, reforzado con armaduras de acero y reforzado con fibras de acero), el nivel de carga (20 y 40%) y la excentricidad de la carga (0, 20 y 50 mm). Todos los pilares ensayados tienen una longitud total de 3180 mm y un diametro exterior de 159 mm, siendo el espesor de la pared del tubo de acero de 6 mm. Como condiciones de contorno se considera empotrado el extremo inferior de cada pilar y articulado el superior, siendo el valor de la esbeltez relativa a temperatura ambiente de los pilares superior a 0,5 en todos los casos analizados. Finalmente, los resultados obtenidos en los ensayos experimentales se comparan con las previsiones de diferentes metodos de calculo simplificado propuestos por la normativa vigente a nivel internacional con el fin de validar la precision de estos metodos, confirmando que el Eurocodigo 4 proporciona predicciones inseguras para pilares circulares esbeltos CFT sometidos a cargas centradas y excesivamente conservadoras cuando la carga es excentrica.
Bases de subsistencia de los pobladores de Erralla: Macromamíferos

Los restos de alimentacion de los hombres que frecuentaron la cueva de Erralla pertenecen en su inmensa mayoria a restos de Mamiferos y entre ellos principalmente a Ungulados. Existen ademas algunos pocos restos de Aves consumidas probablemente por el hombre, pero la inmensa mayoria de las Aves son huesos de Paseriformes hallados en determinadas zonas del yacimiento junto con Micromamiferos y Anfibios, residuos de egagropilas de Estrigiformes o rapaces nocturnas.
Quality-of-Life Outcomes After Bone-Anchored Hearing Device Surgery in Children With Single-Sided Sensorineural Deafness

Objective To report our experience in a series of children with single-sided sensorineural deafness where a bone-anchored hearing device (BAHD) was used for auditory rehabilitation. Study Design Retrospective case review. Setting Tertiary referral centre. Patients Eight children (4 boys and 4 girls) who had BAHD surgery for single-sided sensorineural deafness between 2007 and 2010. Intervention(s) Bone-anchored hearing device was used for auditory rehabilitation. Main Outcome Measure(s) Glasgow Children’s Benefit Inventory (GCBI), Single-sided Deafness (SSD) Questionnaire and change in health benefit scores (visual analogue scale). Results All but one of the children showed a positive GCBI score; the child that reported a negative score was because of low self confidence and self-esteem issues secondary to bullying at school. The results of the SSD questionnaire were generally positive with a mean satisfaction score of the BAHD as 9/10. All the children had an improvement in heath benefit. Conclusion Our findings add further evidence to support patient perceived benefit of a BAHD in single sided sensorineural deafness in the paediatric population.
Efficacy of morantel tartrate in a sustained release bolus on the control of subclinical gastrointestinal parasitism in first-year grazing dairy replacements.

Thirty-four heifers (24 Holstein, 8 Ayrshire, 2 Jersey) and 12 Holstein steer calves were grouped into 23 blocks of 2 animals each according to breed, sex, and body weight. Animals in each block were randomly assigned to control or treated groups. The treated group received an anthelmintic bolus containing morantel tartrate before they were permitted access to pasture. A 2.6 ha pasture was divided in half with a double fence; the resulting two pastures had separate feed and water troughs. Steer calves were slaughtered upon termination of the trial to ascertain gastrointestinal parasite burdens. Two worm-free tracer calves were placed on each pasture every 2 mo and slaughtered after 4 wk of grazing to determine parasite infectivity of pastures. Herbage samples were obtained monthly and analyzed for infective larvae. The trial was conducted for 141 d during the grazing season. Treatment resulted in 90% reduction in infective larvae on pasture, 74% reduction in fecal worm-eggs, 91% reduction in adult worm burdens, and a trend toward reduced worm burdens in tracer calves by 52%. An overall average daily gain of . 68 and . 88 kg was obtained for control and treated animals. Reproductive data for the heifers remaining in the herd from the trial showed that treatment resulted in 44 less days to first breeding.
Recorded Music in American Life: The Phonograph and Popular Memory, 1890-1945

Have records, compact discs, and other sound reproduction equipment merely provided American listeners with pleasant diversions, or have more important historical and cultural influences flowed through them? Do recording machines simply capture what's already out there, or is the music somehow transformed in the dual process of documentation and dissemination? How would our lives be different without these machines? Such are the questions that arise when we stop taking for granted the phenomenon of recorded music and the phonograph itself. Now comes an in-depth cultural history of the phonograph in the United States from 1890 to 1945. William Howland Kenney offers a full account of what he calls "the 78 r.p.m. era"-from the formative early decades in which the giants of the record industry reigned supreme in the absence of radio, to the postwar proliferation of independent labels, disk jockeys, and changes in popular taste and opinion. By examining the interplay between recorded music and the key social, political, and economic forces in America during the phonograph's rise and fall as the dominant medium of popular recorded sound, he addresses such vital issues as the place of multiculturalism in the phonograph's history, the roles of women as record-player listeners and performers, the belated commercial legitimacy of rhythm-and-blues recordings, the "hit record" phenomenon in the wake of the Great Depression, the origins of the rock-and-roll revolution, and the shifting place of popular recorded music in America's personal and cultural memories. Throughout the book, Kenney argues that the phonograph and the recording industry served neither to impose a preference for high culture nor a degraded popular taste, but rather expressed a diverse set of sensibilities in which various sorts of people found a new kind of pleasure. To this end, Recorded Music in American Life effectively illustrates how recorded music provided the focus for active recorded sound cultures, in which listeners shared what they heard, and expressed crucial dimensions of their private lives, by way of their involvement with records and record-players. Students and scholars of American music, culture, commerce, and history-as well as fans and collectors interested in this phase of our rich artistic past-will find a great deal of thorough research and fresh scholarship to enjoy in these pages.
Valuing Simplicity: Developing a Good Point of Care Diagnostic

Point-of-care testing promises laboratory-based precision in settings that do not have easy access to laboratories or where processing tests takes too long or is too costly. Developers and global health actors stress values and norms such as simplicity, rapidity and accuracy for realizing diagnostic innovations that work at point of care and are aligned to the specific requirements of point-of-care settings. This paper uses fieldwork among diagnostic manufacturers, scientists, donors, members of civil society, industry consultants, international organizations, regulators, policymakers, programme officers, lab technicians, and clinicians involved in development and implementation of tuberculosis and HIV diagnostics, to examine how norms and values of what constitutes a good point-of-care diagnostic are operating in practice through both top-down and bottom-up dynamics. It draws the link between design, evidence and adoption of diagnostics and how the different actors interpret the values underpinning the new practice. The analysis draws on literature on valuation practices, evidence-making and technology design in science and technology studies and medical sociology. The findings reveal how these values constitute innovation, implementation, and evaluation practices across global and local (India) sites, with important consequences for funding of health infrastructure, capacity, and training resources for addressing some of the existing structural inequalities. Dominant values currently defining point of care diagnostics risk exacerbating health inequalities between those who do and do not have the necessary social and financial resources to access better equipped and functioning healthcare facilities, especially in resource constrained settings.
Cloning of endogenous murine leukemia virus-related sequences from chromosomal DNA of BALB/c and AKR/J mice: identification of an env progenitor of AKR-247 mink cell focus-forming proviral DNA

Recombinant phages containing murine leukemia virus (MuLV)-reactive DNA sequences were isolated after screening of a BALB/c mouse embryo DNA library and from shotgun cloning of EcoRI-restricted AKR/J mouse liver DNA. Twelve different clones were isolated which contained incomplete MuLV proviral DNA sequences extending various distances from either the 5' or 3' long terminal repeat (LTR) into the viral genome. Restriction maps indicated that the endogenous MuLV DNAs were related to xenotropic MuLVs, but they shared several unique restriction sites among themselves which were not present in known MuLV proviral DNAs. Analyses of internal restriction fragments of the endogenous LTRs suggested the existence of at least two size classes, both of which were larger than the LTRs of known ecotropic, xenotropic, or mink cell focus-forming (MCF) MuLV proviruses. Five of the six cloned endogenous MuLV proviral DNAs which contained envelope (env) DNA sequences annealed to a xenotropic MuLV env-specific DNA probe; in addition, four of these five also hybridized to an ecotropic MuLV-specific env DNA probe. Cloned MCF 247 proviral DNA also contained such dual-reactive env sequences. One of the dual-reactive cloned endogenous MuLV DNAs contained an env region that was indistinguishable by AluI and HpaII digestion from the analogous segment in MCF 247 proviral DNA and may therefore represent a progenitor for the env gene of this recombinant MuLV. In addition, the endogenous MuLV DNAs were highly related by AluI cleavage to the Moloney MuLV provirus in the gag and pol regions.
Machine Learning Approaches to Energy Consumption Forecasting in Households

We consider the problem of power demand forecasting in residential micro-grids. Several approaches using ARMA models, support vector machines, and recurrent neural networks that perform one-step ahead predictions have been proposed in the literature. Here, we extend them to perform multi-step ahead forecasting and we compare their performance. Toward this end, we implement a parallel and efficient training framework, using power demand traces from real deployments to gauge the accuracy of the considered techniques. Our results indicate that machine learning schemes achieve smaller prediction errors in the mean and the variance with respect to ARMA, but there is no clear algorithm of choice among them. Pros and cons of these approaches are discussed and the solution of choice is found to depend on the specific use case requirements. A hybrid approach, that is driven by the prediction interval, the target error, and its uncertainty, is then recommended.
A Study of the Importance of Clonus Symptoms in Patients with Tramadol Poisoning

Objectives Clinical studies to reduce the side effects of tramadol, such as seizure, are necessary. Owing to the high prevalence of tramadol consumption and subsequent complications that result from seizures, the aim of the present study was to find a relationship between clonus and prediction of seizure outcome in patients with tramadol overdose. This can be used to determine the need for essential actions if a significant indicator of preventive medical measures is observed. Methods In this case-control study, three groups of patients poisoned with tramadol and with marked ankle clonus were evaluated. A sample size of 50 patients per group was calculated using the Cohen first method. The data were analyzed using SPSS16 software. Results All patients with ankle clonus were evaluated. Seizures occurred most commonly in patients aged 21–25 years or younger. The patients who received the preventive medication of magnesium sulfate were seizure-free for 72 h after admission. Conclusion It is recommended that, for all patients referred with tramadol poisoning who have symptoms of ankle clonus, the administration of magnesium sulfate should be considered in addition to medication for the prevention of seizures and arrhythmias.
Detection of loss of heterozygosity at the human TP53 locus using a dinucleotide repeat polymorphism

Loss of heterozygosity at the TP53 locus occurs frequently in many types of cancer and requires polymorphic markers for detection. Several polymorphisms at the TP53 locus have been described previously, and polymerase chain reaction (PCR)‐based assays have been developed to detect these polymorphisms. However, these polymorphisms have relatively low levels of heterozygosity and are often uninformative. We report here the detection of loss of heterozygosity at the TP53 locus in various human cancers by using a highly informative dinucleotide repeat polymorphism.
Probabilistic localization and mapping in appearance space

This thesis is concerned with the problem of place recognition for mobile robots. How can a robot determine its location from an image or sequence of images, without any prior knowledge of its position, even in a world where many places look identical? We outline a new probabilistic approach to the problem, which we call Fast Appearance Based Mapping or FAB-MAP. Our map of the environment consists of a set of discrete locations, each with an associated appearance model. For every observation collected by the robot, we compute a probability distribution over the map, and either create a new location or update our belief about the appearance of an existing location. The technique can be seen as a new type of SLAM algorithm, where the appearance of locations (rather than their position) is subject to estimation. Unlike existing SLAM systems, our appearance based technique does not rely on keeping track of the robot in any metric coordinate system. Thus it is applicable even when informative observations are available only intermittently. Solutions to the loop closure detection problem, the kidnapped robot problem and the multi-session mapping problem arise as special cases of our general approach. Abstract Our probabilistic model introduces several technical advances. The model incorporates correlations between visual features in a novel way, which is shown to improve system performance. Additionally, we explicitly compute an approximation to the partition function in our Bayesian formulation, which provides a natural probabilistic measure of when a new observation should be assigned to a location not already present in the map. The technique is applicable even in visually repetitive environments where many places look the same. Abstract Finally, we define two distinct approximate inference procedures for the model. The first of these is based on concentration inequalities and has general applicability beyond the problem considered in this thesis. The second approach, built on inverted index techniques, is tailored to our specific problem of place recognition, but achieves extreme efficiency, allowing us to apply FAB-MAP to navigation problems on the largest scale. The thesis concludes with a visual SLAM experiment on a trajectory 1,000 km long. The system successfully detects loop closures with close to 100% precision and requires average inference time of only 25 ms by the end of the trajectory.
Organization of intrahippocampal projections originating from CA3 pyramidal cells in the rat

The distribution of intrahippocampal projections arising from the CA3 region of the rat hippocampus was investigated using in vitro and in vivo methods. In the in vitro hippocampal slice preparation, single CA3 pyramidal cells were intracellularly labeled with horseradish peroxidase (HRP), and the three‐dimensional organization of the axonal plexus was analyzed by using a computer‐aided digitizing system. As many as eight primary collaterals originated from the principal axon of CA3 pyramidal cells and these commonly bifurcated further and innervated stratum oriens and stratum radiatum of CA3 and CA1. Within the 400 μm slice, the summed length of all visible collaterals per neuron ranged from 2.6 mm to approximately 12.5 mm. While the CA3 principal axon tended to be relatively smooth, the axonal collaterals bore numerous varicosities that electron microscopy confirmed to be presynaptic boutons. These varicosities occurred, on average, once every 7 μm of collateral length. The distribution of axonal collaterals differed depending on the location of the parent pyramidal cell. Only rarely could CA3 collaterals be followed in the slice to their terminations within CA1.
Data Allocation Optimization for Hybrid Scratch Pad Memory With SRAM and Nonvolatile Memory

Embedded systems normally have a tight energy budget. Since the on-chip cache typically consumes 25%-50% of the processor's area and energy consumption, scratch pad memory (SPM), which is a software-controlled on-chip memory, has been widely adopted in many embedded systems due to its smaller area and lower power consumption. However, as the speed of the CMOS transistors increases along with density, leakage power consumption is becoming a critical issue for memory components with a large number of transistors. In this paper, we propose a novel hybrid SPM which consists of static random-access memory (SRAM) and nonvolatile memory (NVM) to take advantage of the ultralow leakage power and high density of latter. A novel dynamic data management algorithm is also proposed to make use of the full potential of NVM. According to the experimental results, with the help of the proposed algorithm, the novel hybrid SPM architecture can reduce the memory access time by 18.17%, the dynamic energy by 24.29%, and the leakage power by 37.34% compared with a baseline pure SRAM SPM with the same area.
TOXICOLOGICAL EFFECTS OF AFLATOXIN B 1 ON GROWTH PERFORMANCE , HUMORAL IMMUNE RESPONSE AND BLOOD PROFILE OF JAPANESE QUAIL

Toxic effects of Aflatoxin B1 on growth performance and humoral immune response against Newcastle disease Virus (NDV) vaccine were determined in Japanese quails. Quail chicks (n=300) were divided into five groups and each group was further sub-divided into two subgroups. One subgroup of each group was vaccinated with NDV vaccine to study the antibody response. Experimental diets were prepared by adding different levels of AFB1 i.e. 0.25mg/kg feed, 0.5mg/kg feed, 1 mg/kg feed and 2 mg/kg feed, and were offered to groups B, C, D and E respectively for 42 days, while group A was kept as control. Feed intake, body weight gain and feed conversion ratio were calculated on weekly basis. The Antibody titers of vaccinated quails were measured by haemagglutination inhibition test. Hematological parameters Erythrocyte sedimentation rate, Hb content, hematocrit and total leukocyte count were measured in AFB1 fed birds and were compared with the quails given basal diet. Results showed significant reduction (P≤0.05) in feed intake, weight gain and feed conversion ratio, when compared to control group. Moreover, anti-NDV antibody titre was significantly reduced (P≤0.05) in AFB1 fed groups. Hb content, hematocrit, and TLC had time and dose dependent decrease in AFB1 fed quails while ESR was increased significantly in AFB1 fed birds. This highlighted adverse effects of AFB1 on growth performance, humoral immune response and blood profile of quails.
A comparative study of two methods of synthetic phonics instruction for learning how to read: Jolly Phonics and THRASS

The National Strategy for Primary Schools in England (2006) advocates synthetic phonics as a means for teaching children to read. No studies exist to date comparing the effectiveness of different commercially available synthetic phonics methods. This case study compared two schools at which Jolly Phonics (JP) was taught with one school at which THRASS (Teaching Handwriting, Reading and Spelling Skills) was taught at Reception level (4 to 5 years) over a one-year period. Reading ability for words and non-words as well as short-term memory ability for words and phonemes improved in all schools. However, reading ability improved more in one JP school compared to the THRASS school, with no differences between the other JP school and the THRASS school. This paper considers how particular variables may mask instruction method effects, and advocates taking such factors into account for a more comprehensive future evaluation of synthetic phonics methods.
Paradoxical decreases in high-density lipoprotein cholesterol with fenofibrate: a quite common phenomenon

Background: Reduced high-density lipoprotein cholesterol (HDL-C) concentration is considered to be an independent risk factor for cardiovascular morbidity and mortality. Fibrates are useful in managing dyslipidaemia; reports highlight an expected increase in HDL-C of 10–15% in conjunction with falls in plasma triglycerides of ∼30%. Despite this, there are several reported cases of paradoxical decreases in HDL-C caused by fibrate treatment. Aim: To report the second largest observational study to date. Methods: Fenofibrate use at a regional lipid clinic was associated with reductions in HDL-C in a considerable proportion of patients, necessitating cessation of the medication. In view of this, characteristics of the first 94 patients to be given fenofibrate were retrospectively analysed, and comparisons were made between those whose profiles responded as expected and those experiencing paradoxical decreases in HDL-C. Results: 94 patients (57 male; mean (SD) age 52.5 (12.5) years; mean (SD) body mass index 28.9 (4.5) kg/m2) were assessed. After 8–12 weeks on daily fenofibrate (200 mg micronised or equivalent), 43 of the patients (46%) showed a paradoxical decrease in HDL-C (in nine the decrease was >50% from baseline). When responses to fenofibrate were compared against baseline variables, there were no significant differences between groups other than a higher baseline HDL-C (p = 0.045) in patients responding appropriately. Conclusions: Fenofibrate was associated with a reduction in HDL-C in almost half the patients studied. This is substantially more than in most studies reported to date. Other HDL-C-raising strategies need to be considered in these patients, and the mechanisms need to be explored.