Miracle-dz/UniFAR-FTUs huggingface dataset:
The Development of Japanese Passive Syntax as Indexed by Structural Priming in Comprehension

A number of previous studies reported a phenomenon of syntactic priming with young children as evidence for cognitive representations required for processing syntactic structures. However, it remains unclear how syntactic priming reflects children's grammatical competence. The current study investigated structural priming of the Japanese passive structure with 5- and 6-year-old children in a visual-world setting. Our results showed a priming effect as anticipatory eye movements to an upcoming referent in these children but the effect was significantly stronger in magnitude in 6-year-olds than in 5-year-olds. Consistently, the responses to comprehension questions revealed that 6-year-olds produced a greater number of correct answers and more answers using the passive structure than 5-year-olds. We also tested adult participants who showed even stronger priming than the children. The results together revealed that language users with the greater linguistic competence with the passives exhibited stronger priming, demonstrating a tight relationship between the effect of priming and the development of grammatical competence. Furthermore, we found that the magnitude of the priming effect decreased over time. We interpret these results in the light of an error-based learning account. Our results also provided evidence for prehead as well as head-independent priming.
Exploring genotypic variations for improved oil content and healthy fatty acids composition in rapeseed (Brassica napus L.).

BACKGROUND Development of new genotypes having high oil content and desirable levels of fatty acid compositions is a major objective of rapeseed breeding programmes. In the current study combining ability was determined for oil, protein, glucosinolates and various fatty acids content using 8 × 8 full diallel in rapeseed (Brassica napus). RESULTS Highly significant genotypic differences were observed for oil, protein, glucosinolates, oleic acid, linolenic acid and erucic acid content. Mean squares due to general combining ability (GCA), specific combining ability (SCA) and reciprocal combining ability (RCA) were highly significant (P ≤ 0.01) for biochemical traits. Parental line AUP-17 for high oil content and low glucosinolates, genotype AUP-2 for high protein and oleic acids, and AUP-18 for low lenolenic and erucic acid were best general combiners. Based on desirable SCA effects, F1 hybrids AUP-17 × AUP-20; AUP-2 × AUP-8; AUP-7 × AUP-14; AUP-2 × AUP-9; AUP-7 × AUP-14 and AUP-2 × AUP-9 were found superior involving at least one best general combiner. CONCLUSION F1 hybrids AUP-17 × AUP-20 (for oil content); AUP-2 × AUP-8 (for protein content); AUP-7 × AUP-14 (for glucosinolates); AUP-2 × AUP-9 (for oleic acid); AUP-7 × AUP-14 (for linolenic acid) and AUP-2 × AUP-9 (for erucic acid) were found superior involving at least one best general combiner. As reciprocal crosses of AUP-14 with AUP-7 and AUP-8 were superior had low × low and low × high GCA effects for glucosinolates and oleic acid, respectively therefore, these could be exploited in future rapeseed breeding programmes to develop new lines with good quality. © 2016 Society of Chemical Industry.
Axenfeld–Rieger malformation and distinctive facial features: Clues to a recognizable 6p25 microdeletion syndrome

Deletion of distal 6p is associated with a distinctive clinical phenotype including Axenfeld–Rieger malformation, hearing loss, congenital heart disease, dental anomalies, developmental delay, and a characteristic facial appearance. We report the case of a child where recognition of the specific ocular and facial phenotype, led to identification of a 6p microdeletion arising from a de novo 6:18 translocation. Detailed analysis confirmed deletion of the FOXC1 forkhead gene cluster at 6p25. CNS anomalies included hydrocephalus and hypoplasia of the cerebellum, brainstem, and corpus callosum with mild to moderate developmental delay. Unlike previous reports, hearing was normal. © 2005 Wiley‐Liss, Inc.
Assisted reproductive technologies and monozygous twins: implications for future study and clinical practice

Abstract That the zona pellucida (ZP) plays a prominent role in the physiology of some human twinning is an attractive, albeit incompletely proven, medical hypothesis. Indeed, an association has been proposed between manipulation of the ZP and/or native ZP microarchitecture and monozygotic (MZ) twins. Ovulation induction also has been theoretically linked to in vivo ZP alterations facilitating MZ twin development. In vitro fertilization (IVF) relies on necessary (and, in some cases extended) embryo culture techniques potentially creating subtle ZP changes and subsequent MZ twinning. With growing experience in the assisted reproductive technologies and particularly IVF, some preliminary reports have noted an increased frequency of MZ twins after procedures that artificially breach the ZP (i.e., intracytoplasmic sperm injection [ICSI], or ‘assisted hatching’). Such ZP manipulations ostensibly enhance oocyte fertilization or facilitate blastocyst hatching, thus improving pregnancy rates for couples undergoing fertility treatment. Evidence exists both to challenge and support the connection between these phenomena and MZ twins. This report outlines the fundamental embryological processes believed responsible for these conflicting observations; the current literature on the subject of human ZP micro-manipulation and MZ twins is also discussed. Twin Research (2000) 3, 217–223.
Fibrin Sealant for Mesh Fixation in Endoscopic Inguinal Hernia Repair: Is There Enough Evidence for Its Routine Use?

Fibrin sealing has recently evolved as a new technique for mesh fixation in endoscopic inguinal hernia repair. A comprehensive Medline search was carried out evaluating fibrin sealant for mesh fixation, and finally 12 studies were included (3 randomized trials, 3 nonrandomized trials, and 6 case series). The trials were assessed for operative time, seroma formation, recovery time, recurrence rate, and acute and chronic pain.There was a trend toward decreased operative times for fibrin sealing compared with mechanical stapling; however, the results for seroma formation remained contradictory. The most important finding was the reduced postoperative pain. Recovery times were lower after fibrin sealing and the recurrence rates showed no differences.Fibrin sealing for mesh fixation in the endoscopic inguinal hernia surgery is a promising alternative to mechanical stapling, which can be safely applied. As the overall quality of published data remains poor, further well-designed studies are needed until fibrin sealing can replace mechanical stapling as a new standard for mesh fixation.
Assessment of Feline Ehrlichiosis in Central Spain Using Serology and a Polymerase Chain Reaction Technique

Abstract: Antibodies to Ehrlichia spp. and inclusion bodies compatible with Ehrlichia spp. in feline blood cells have been previously detected in Spain. The aim of this study was to assess the presence of antibodies to E. canis, N. risticii, and A. phagocytophilum in 122 feline serum samples from Madrid (central Spain). In addition, Ehrlichia genus‐specific, one‐tube, nested polymerase chain reaction (PCR) was performed from blood samples from these cats. Of the cats, 10.6% were seropositive for E. canis, 2.4% were positive for N. risticii, and 4.9% were seropositive for A. phagocytophilum. Two N. risticii‐positive cats and one animal seropositive to A. phagocytophilum were also seropositive for E. canis. Despite these seropositive results, all the blood samples analyzed by PCR were negative. Our results demonstrate reactivity against agents implicated in feline ehrlichiosis in Spain. Further studies should be performed in order to clarify the significance of serology and PCR in the diagnosis of feline ehrlichiosis.
Break Index (BI) annotated speech corpus for Urdu TTS

This study presents 10 hours of speech corpus annotated at Break Index (BI) level for Urdu text to speech system (TTS). For the speech corpus annotation, 5-steps scale of BI is presented in this study, which assists us to understand the prosodic relationship between word boundaries and phrase boundaries in Urdu. Moreover, an algorithm for Urdu TTS is designed to detect the 5-steps scale of BI automatically using acoustic cues such as duration of phrasal breaks, intonational patterns, glottalization and phrase lengthening. This algorithm annotates 10 hours of speech automatically and reports 98.4% accuracy compared to perceptual marked BI. This research also discusses the controversial issue of prosody to syntax mapping and syntax to prosody mapping in Urdu. The results indicate: (i) in the context of noun phrase and case phrase (NP-KP), prosodic break occurs between NP-KP to eliminate syntactic ambiguity; (ii) string of KPs does not require explicit prosodic break because case markers act as phrase separators in KP-KP context (iii) verb phrase (VP) in an utterance is preceded by a prosodic break to differentiate it from other phrases in an utterance and (iv) NPs of complex predicates prosodically act as single unit in an utterance.
Physiology and Endocrinology of the Ovarian Cycle in Macaques

Macaques provide excellent models for preclinical testing and safety assessment of female reproductive toxicants. Currently, cynomolgus monkeys are the predominant species for (reproductive) toxicity testing. Marmosets and rhesus monkeys are being used occasionally. The authors provide a brief review on physiology and endocrinology of the cynomolgus monkey ovarian cycle, practical guidance on assessment and monitoring of ovarian cyclicity, and new data on effects of social housing on ovarian cyclicity in toxicological studies. In macaques, cycle monitoring is achieved using daily vaginal smears for menstruation combined with cycle-timed frequent sampling for steroid and peptide hormone analysis. Owing to requirements of frequent and timed blood sampling, it is not recommended to incorporate these special evaluations into a general toxicity study design. Marmosets lack external signs of ovarian cyclicity, and cycle monitoring is done by regular determinations of progesterone. Cynomolgus and marmoset monkeys do not exhibit seasonal variations in ovarian activity, whereas such annual rhythm is pronounced in rhesus monkeys. Studies on pair- and group-housed cynomolgus monkeys revealed transient alterations in the duration and endocrinology of the ovarian cycle followed by return to normal cyclicity after approximately six months. This effect is avoided if the animals had contact with each other prior to mingling. These experiments also demonstrated that synchronization of ovarian cycles did not occur. Competing Interests: This article was sponsored by Covance Inc. and Schering-Plough. Gerhard F. Weinbauer, Marc Niehofg, Michael Niehaus, Shiela Srivasav, and Antje Fuchs are employed by Covance Inc. Eric Van Esch is employed by Schering-Plough. No other competing interests were declared.
Using polymerase chain reaction to human papillomavirus in oral and pharyngolaryngeal carcinomas.

PURPOSE Increasingly, evidence has shown that human papillomavirus (HPV) plays a role in the induction of certain carcinomas. The presence of HPV sequences in 56 previously untreated oral and pharyngolaryngeal carcinomas was examined by the polymerase chain reaction (PCR). MATERIALS AND METHODS After DNA extraction, samples underwent 40 replication cycles with specific oligonucleotide primers corresponding to sequences from the E6 open-reading frame of HPV-6b, HPV-16, and HPV-18. To determine the E6 genomic integration, positive samples were processed with specific primers for the corresponding HPV L1 genes. Genomic HPV DNA clones into PBR 322 was used as positive control. RESULTS HPV E6 DNA of the 6b and 16 types was detected in 14 patients (25%). The L1 gene was not present. CONCLUSION Detected HPV E6 DNA might be integrated into the cell genome in the positive cases as indicated by the absence of the L1 gene-coding for the viral capside. Histological and survival rates, were unrelated to the presence of HPV.
Vital capacity as a predictor of outcome in elderly patients with rib fractures.

BACKGROUND This study tests the relationships between early bedside vital capacity (VC) measurement and morbidity, mortality, and resource consumption in geriatric blunt chest trauma patients with rib fractures. METHODS This was a retrospective study examining all patients > or = 65 years old with rib fractures who had a VC measured within 48 hours of their emergency department evaluation. Outcome variables included pulmonary complications, death from pulmonary complications, hospital length of stay (LOS), intensive care unit length of stay (ICU LOS), and discharge disposition. RESULTS Thirty-eight patients met the study criteria. The mean age was 80.2 (+/-7.4) years, the mean number of rib fractures was 3.6 (+/-1.6), and the mean ISS was 6.9 (+/-4.7). VC and the percentage of the predicted vital capacity (pVC) were both inversely correlated with LOS (p = 0.0076 and p = 0.0172, respectively). Linear regression analysis suggested that patients with a VC < 1.4 L or < 55% of their pVC had a LOS > 3 days. Mean VC was 36% higher in patients who were discharged home versus those discharged to an extended care facility (ECF; p = 0.025). There was a trend toward significance when comparing VC to ICU LOS (p = 0.079), but none in predicting pulmonary complications (p = 0.3299). No correlations between VC and mortality can be drawn given the single death in the cohort. CONCLUSIONS Bedside VC is a simple measurement which could predict LOS in elderly patients with rib fractures and may identify those patients requiring ECF upon discharge. Further prospective study may highlight the utility of emergency room VC in determining the disposition of these patients.
Production of a monoclonal antibody to Vibrio cholerae non-O1 heat-stable enterotoxin (ST) which is cross-reactive with Yersinia enterocolitica ST

A monoclonal antibody (MAb) against synthetic heat-stable enterotoxin of Vibrio cholerae non-O1 (NAG-ST) was produced. The MAb, namely, 2F, belonged to the immunoglobulin G1 class. Ascitic fluid drawn from pristane-primed BALB/c mice injected with a 2F-producing clone demonstrated anti-NAG-ST activity which could be detected in enzyme-linked immunosorbent assay even at a dilution of 1:128,000. Fifty-fold-diluted ascitic fluid could completely neutralize the activity of NAG-ST (synthetic and native) and Vibrio mimicus ST (identical to NAG-ST) in suckling mice. In the same assay, 2F could also neutralize Yersinia enterocolitica ST (Y-ST) but did not neutralize Escherichia coli STh and STp. A similar pattern of reactivity occurred in a competitive enzyme-linked immunosorbent assay with homologous and heterologous toxins. Competitive inhibition curves with synthetic peptides representing NAG-ST and its shorter analogs revealed that aspartic acid located at position 2 from the N terminus of NAG-ST was the essential residue of the recognized epitope. Significantly, in Y-ST, to which 2F cross-reacted, aspartic acid is in the corresponding position as that of NAG-ST, thereby confirming our conclusions that the epitope defining this MAb is aspartic acid.
Localization of the Chaperone Proteins GRP78 and HSP60 on the Luminal Surface of Bovine Oviduct Epithelial Cells and Their Association with Spermatozoa1

Abstract Upon their transit through the female genital tract, bovine spermatozoa bind to oviduct epithelial cells, where they are maintained alive for long periods of time until fertilization. Although carbohydrate components of the oviduct epithelial cell membrane are involved in these sperm/oviduct interactions, no protein candidate has been identified to play this role. To identify the oviduct factors involved in their survival, sperm cells were preincubated for 30 min with apical membranes isolated from oviduct epithelial cells, washed extensively, and further incubated for up to 12 h in the absence of apical membranes. During this incubation, sperm viability, motility, and acrosomal integrity were improved compared with cells preincubated in the absence of apical membranes. This suggests that, during the 30-min preincubation with apical membrane extracts, either an oviductal factor triggered intracellular events resulting in positive effects on spermatozoa or that such a factor strongly attached to sperm cells to promote a positive action. Similarly, spermatozoa were incubated with apical membranes isolated from oviduct epithelial cells labeled with [35S]-methionine and, upon extensive washes, proteins were separated by two-dimensional (2-D) gel electrophoresis to identify the factors suspected to have beneficial effects on spermatozoa. The six major proteins, according to their signal intensity on the autoradiographic film, were extracted from a 2-D gel of oviduct epithelial cell proteins run in parallel and processed for N-terminal sequencing of the first 15 amino acids. Of these, one was identical to heat shock protein 60 (HSP60) and one to the glucose-regulated protein 78 (GRP78). Their identities and association with spermatozoa were confirmed using an antibody directed against these proteins. This paper reports the localization of both GRP78 and HSP60 on the luminal/apical surface of oviduct epithelial cells, their binding to spermatozoa, and the presence of endogenous HSP60 in the sperm midpiece.
[The influencing factors on suicide attempt among adolescents in South Korea].

PURPOSE Suicide has been considered a large public health concern in recent years because suicide mortality has been increasing rapidly. This study was done to investigate the prevalence and risk factors of a suicide attempt among adolescents in South Korea. METHODS The data of the 2006 Youth Health Risk Behavior web-based Survey collected by the Korean Center for Disease Control was analyzed using logistic regression for this study. RESULTS The prevalence of a suicide attempt was 5.2% in South Korea. The risk factors of a suicide attempt were suicidal ideation (odds 31.83), depression (odds 7.98), drug use (odds 4.67), currently smoking (odds 3.19), feeling unhappiness (odds 2.77), stress (odds 2.60), currently drinking alcohol (odds 2.39), sexual activity (odds 2.33), living with neither parent (odds 2.24), initial alcohol drinking by age 9 (odds 1.80), health status (odds 2.15), skipped breakfast (odds 1.75), disease (odds 1.65), and school records (odds 1.22). CONCLUSION Suicide screening and prevention programs should be developed, considering these risk factors. Suicide prevention programs should be applied to the at risk population prior to a suicide attempt.
Computed imaging stereotaxy: experience and perspective related to 500 procedures applied to brain masses.

The evolution of more sophisticated imaging techniques has initiated a renewed interest in stereotactic devices, methods, and applications. The Brown-Roberts-Wells instrument was available to us early in its prototype stage, and this report reviews the first 500 cases using the system at the University of Southern California Medical Center Hospitals. Procedures were undertaken after recognition of apparent structural alterations on imaging studies, with objectives being both diagnostic and therapeutic. Target locations were predominantly within the cerebral centrum-basal ganglia (284 cases) and diencephalic-mesencephalic regions (129 cases). Operative objectives included: histological and microbiological assay, cyst and abscess aspiration, installation of temporary or permanent drainage conduits, point source and colloid base brachytherapy, cerebroscopy and ventriculoscopy with biopsy, aspiration, and excision, and intraoperative vascular localization. Using multiple instrumentation at the target point (741 point placements), we realized procedural objectives in 95.6% of the cases. The mortality was 0.2% and the morbidity was 1%: hematoma, 2 cases; infection, 1 case; increased deficit, 1 case; intraprocedural seizure, 1 case. A specific diagnosis was not obtained in 4.4% (necrosis, 10 cases; inflammatory response, 9 cases; granuloma, 1 case; gliosis, 1 case; diagnostic error, 1 case). Individual guidelines for case selection, technique, institutional requirements, and applications of the method are discussed. (ABSTRACT TRUNCATED AT 250 WORDS)
Macroprudential and Monetary Policy Interactions in a DSGE Model for Sweden

We analyse the effects of macroprudential and monetary policies and their interactions using an estimated dynamic stochastic general equilibrium (DSGE) model tailored to Sweden. Households face a ceiling on their loan-to-value ratio and must amortize their mortgages. The government grants mortgage interest payment deductions. Lending rates are affected by mortgage risk weights. We find that demand-side macroprudential measures are more effective in curbing household debt ratios than monetary policy, and they are less costly in terms of foregone consumption. A tighter macroprudential stance is also found to be welfare improving, by promoting lower consumption volatility in response to shocks, especially when using a combination of macroprudential instruments.
Report - Screening of the Anti-hyperglycemic activity of some medicinal plants of Jordan.

Diabetes represents a group of common diseases that are characterized by dysregulation of blood glucose levels. Plants are traditionally used for management of diseases including diabetes. In this study, we screened the anti-diabetic effect of extracts of 21 plants grown in Jordan. Extracts of plants were screened for their antihyperglycemic activity. Diabetes was induced in Sprague Dawley rats using Alloxan. Plant extracts were dosed at 1gm/kg. Blood glucose was measured at baseline and at every hour for 3 hours. Results showed that five plants out of the 21 screened showed antihyperglycemic activity. These plants are Phoenix dactylifera L. , Tecoma stans (L.) Kunth, Cichorium pumilum Jacq. , Phaseolus vulgaris L. , and Teucrium polium L. On the other hand, Sarcopoterium spinosum (L.) Spach. and Brassica oleracea L. var. capitata significantly increased blood glucose levels in diabetic rats. The following plant extracts showed neutral effect on blood glucose levels: Plantago major L. , Taraxacum cyprium H. Lindb, Artemisia inculta Delile, Marrubium vulgare L. , Inula viscosa (L.) Ai, Rubus sanguineus Friv, Coriandrum sativum L. , Cucurbita pepo var ovefera, Cucumis sativus L. , Hordeum vulgare L. , Apium graveolens L. , Avena sativa L. , Helianthus annus L. , and Anethum graveolens L. In conclusion, Jordanian medicinal plants might be useful for managements of blood glucose levels in patients with diabetes.