Miracle-dz/UniFAR-FTUs huggingface dataset:
Optimized intermolecular potential functions for liquid hydrocarbons

Optimized intermolecular potential functions have been determined for hydrocarbons through Monte Carlo simulations of 15 liquids: methane, ethane, propane, n-butane, isobutane, n-pentane, isopentane, neopentane, cyclopentane, n-hexane, 1-butene, cis- and trans-2-butene, isobutene, and benzene. To achieve high accuracy, 12 unique group types were identified and their associated Lennard-Jones parameters were established. The average deviation from experiment for the computed densities and heats of vaporization is 2% and trends for isomeric series are reproduced. Conformation results were also obtained for five liquids and revealed no condensed-phase effects on the conformer populations. Structural analyses focus on trends as a function of chain length and branching of the monomers.
Design of a flexible robot cell demonstrator based on CPPS concepts and technologies

With the Horizon 2020 EU Research and Innovation program, several research activities have developed new concepts for Plug&Produce systems based on Service-oriented Architectures. The H2020 PERFoRM project is aiming to harmonize these concepts and technologies to transform the classic and static manufacturing automation design to flexible Cyber Physical Production Systems (CPPS). To de-risk the CPPS concept, demonstration environments were set up. This paper describes the design and the set-up of a modular and flexible robot cell enable Plug&Produce on module and submodule level.
Telomere length and mortality in the Ludwigshafen Risk and Cardiovascular Health study

Introduction Short telomeres have been associated with adverse lifestyle factors, cardiovascular risk factors and age-related diseases, including cardiovascular disease (CVD), myocardial infarction, atherosclerosis, hypertension, diabetes, and also with mortality. However, previous studies report conflicting results. Objectives The aim of the present study has been to investigate the involvement of telomere length in all-cause and CVD mortality in subjects hospitalized for diagnostic coronary angiography of the Ludwigshafen Risk and Cardiovascular Health (LURIC) study. Methods Relative telomere length (RTL) was measured with a Q-PCR based method in 3,316 participants of the LURIC study. Age-corrected RTL was calculated as the ratio between RTL and age. Median follow-up was 9.9 years. Cox regression and Kaplan-Maier analyses were performed to evaluate the role of RTL for all-cause and cardiovascular mortality. Results RTL correlated negatively with age (r = -0.09; p<0.001). In surviving patients the correlation between age and RTL was statistically significant (r = -0.088; p<0.001), but not in patients who died during follow-up (r = -0.043; p = 0.20). Patients in quartiles 2–4 of RTL had a lower hazard ratio for all-cause mortality (HR:0.822; 95%CI 0.712–0.915; p = 0.008) and CVD-mortality (HR:0.836; 95%CI 0.722–0.969; p = 0.017) when compared to those in the 1st quartile. Adjustment for major cardiovascular risk factors did not change this result, however additional adjustment for age attenuated this effect. Patients in the 4th quartile of age-corrected RTL compared to those in the 1st quartile had a lower hazard ratio for all-cause mortality, even with adjustment for major cardiovascular risk factors. Conclusions The present study supports the hypothesis that short telomere length increases the risk of all-cause and CVD mortality. Age appears to be an important co-variate that explains a substantial fraction of this effect. It remains unclear whether short telomeres contribute directly to the increase in mortality or if they are simply a surrogate marker for other adverse processes of aging.
The physico-chemical properties and nutritional composition of rice bran produced at different milling degrees of rice (

Rice bran was produced by milling the paddy variety MR 220 at different milling degrees (MD) namely 2, 4, 6 and 8%. The proximate content and the effect of different MD on nutritional content and physico-chemical properties of rice bran were studied. The chemical composition of rice bran was significantly affected by the milling process. Among the samples evaluated, rice bran produced at 8% MD had the lowest protein, fat and crude fibre contents. Mineral content was highest for rice bran produced at 6% MD, while the highest vitamin content was found in rice bran produced at 2% MD. The study also indicated that all types of rice bran offer healthier benefits. *MARDI Station, Bukit Raya, P.O. Box 1, 06707 Pendang, Kedah, Malaysia Authors’ full names: Rosniyana Ahmad, Hashifah Mohd Ali and Shariffah Norin Syed Abdullah E-mail: rosa@mardi.my ©Malaysian Agricultural Research and Development Institute 2007 Introduction The utilization of commercial rice bran and its potential food values is recognized and it has recently been increased with the development of highly promising processes and products. The quality and quantity of bran produced at the mill are key factors in the utilization of the by-products (Kent 1983). Improvement in the quality of bran can be achieved by identifying and correcting inadequate milling machinery and/or improving their performances. Removal of the small broken rice grains and the husk particle passing along with bran is essential. One of the factors determining the potential use of bran for food uses is its chemical composition (Juliano and Bechtel 1985). The chemical composition of rice bran depends on several factors associated with the grain itself and the milling process. Major factors associated with the rice grain are varietal and environmental variability, distribution of chemical constituents, thickness of anatomical outer layers, size and shape of grains and resistance of grains to breakage. The machinery, processing and milling conditions are factors associated with the milling process. Friction-type mills produce bran of higher fat content, because they are more effective in removing the aleurone layer. However, the abrasive-type mills remove starchier endosperm at equivalent degrees of milling (Barber 1979). Rice kernel layers at various depths differ greatly in chemical composition (Resurreccion et al. 1979). As the percentage removal of bran may range from 2 to 12, the degree of milling greatly influences the composition of commercial bran. Generally, the differences are small and not great to justify the segregation at the mill site of the individual bran fractions as distinct commercial products.
Too Deep or Not Too Deep?: A Propensity-Matched Comparison of the Analgesic Effects of a Superficial Versus Deep Serratus Fascial Plane Block for Ambulatory Breast Cancer Surgery

Background and Objectives Serratus fascial plane block can reduce pain following breast surgery, but the question of whether to inject the local anesthetic superficial or deep to the serratus muscle has not been answered. This cohort study compares the analgesic benefits of superficial versus deep serratus plane blocks in ambulatory breast cancer surgery patients at Women's College Hospital between February 2014 and December 2016. We tested the joint hypothesis that deep serratus block is noninferior to superficial serratus block for postoperative in-hospital (pre-discharge) opioid consumption and pain severity. Methods One hundred sixty-six patients were propensity matched among 2 groups (83/group): superficial and deep serratus blocks. The cohort was used to evaluate the effect of blocks on postoperative oral morphine equivalent consumption and area under the curve for rest pain scores. We considered deep serratus block to be noninferior to superficial serratus block if it were noninferior for both outcomes, within 15 mg morphine and 4 cm·h units margins. Other outcomes included intraoperative fentanyl requirements, time to first analgesic request, recovery room stay, and incidence of postoperative nausea and vomiting. Results Deep serratus block was associated with postoperative morphine consumption and pain scores area under the curve that were noninferior to those of the superficial serratus block. Intraoperative fentanyl requirements, time to first analgesic request, recovery room stay, and postoperative nausea and vomiting were not different between blocks. Conclusions The postoperative in-hospital analgesia associated with deep serratus block is as effective (within an acceptable margin) as superficial serratus block following ambulatory breast cancer surgery. These new findings are important to inform both current clinical practices and future prospective studies.
Comprehensive quantification of the modified proteome reveals oxidative heart damage in mitochondrial heteroplasmy

Post-translational modifications hugely increase the functional diversity of proteomes. Recent algorithms based on ultratolerant database searching are forging a path to unbiased analysis of peptide modifications by shotgun mass spectrometry. However, these approaches identify only half of the modified forms potentially detectable and do not map the modified residue. Moreover, tools for the quantitative analysis of peptide modifications are currently lacking. Here, we present a suite of algorithms that allow comprehensive identification of detectable modifications, pinpoint the modified residues, and enable their quantitative analysis through an integrated statistical model. These developments were used to characterize the impact of mitochondrial heteroplasmy on the proteome and on the modified peptidome in several tissues from 12-week old mice. Our results reveal that heteroplasmy mainly affects cardiac tissue, inducing oxidative damage to proteins of the oxidative phosphorylation system, and provide a molecular mechanism that explains the structural and functional alterations produced in heart mitochondria. Highlights Identifies all protein modifications detectable by mass spectrometry Locates the modified site with 85% accuracy Integrates quantitative analysis of the proteome and the modified peptidome Reveals that mtDNA heteroplasmy causes oxidative damage in heart OXPHOS proteins
S Sexual Antagonism Hypothesis

Sexual antagonism (or sexual conflict) arises between the sexes when the evolutionary interests of males and females differ (Parker 1979; Chapman et al. 2003; Arnqvist and Rowe 2005). It can be separated into two main forms, known as intralocus and interlocus sexual conflict, which differ in whether the target of selection is a single trait shared by both sexes, or different traits in either sex that interact to influence fitness, respectively. Conflict is the result of selective processes acting differently between the sexes, and may arise due to differences in the strength or direction of sexual selection, natural selection, or both. Sexual conflict ultimately arises when there are fundamental differences in reproductive roles between the sexes (Parker 1979). For example, female mammals carry young during pregnancy, and then suckle infants with milk until they are able to fend for themselves. Male mammals do none of this, and so have a much higher potential reproductive rate than females. Therefore, the best reproductive strategy for females is to focus on rearing healthy offspring, whereas for males it may be to contribute little to parental care, and instead father offspring with as many females as possible. These biological differences thus lead to very different optimal reproductive strategies. Recognition of these evolutionary conflicts of interest between the sexes allows us to explain a variety of adaptations in males and females, especially those relating to reproduction and parental care (Arnqvist and Rowe 2005).
Mining Online Discussion Data for Understanding Teachers’ Reflective Thinking

Teachers’ online discussion text data shed light on their reflective thinking. With the growing scale of text data, the traditional way of manual coding, however, has been challenged. In order to process the large-scale unstructured text data, it is necessary to integrate the inductive content analysis method and educational data mining techniques. An inductive content analysis on samples taken from 17,624 posts was implemented and the categories of teachers’ reflective thinking were obtained. Based on the results of inductive content analysis, we implemented a single-label text classification algorithm to classify the sample data. Then, we applied the trained classification model on a large-scale and unexplored online discussion text data set and two types of visualizations of the results were provided. By using the categories gained from inductive content analysis to create a radar map, teachers’ reflection level was represented. In addition, a cumulative adjacency matrix was created to characterize the evolution of teachers’ reflective thinking. This study could partly explain how teachers reflected in online professional learning environments and brought awareness to educational policy makers, teacher training managers, and education researchers.
A unique, Late Oligocene shrew-like marsupial from western Argentina and the evolution of dental morphology

We describe a new metatherian mammal, Fieratherium sorex gen. et sp. nov., found in western Argentina (Quebrada Fiera locality, southern Mendoza Province), in Late Oligocene deposits (Agua de la Piedra Formation, Deseadan age). The only known specimen is a juvenile with fragments of both dentaries, the right maxilla and a fragment of the left premaxilla with dentition. The loci and the number teeth preserved suggest a dental formula of I? 3/i3, C1/c1, P3/p3, M? 3/m? 3. Fieratherium sorex has a convergent shrew-like appearance and a unique combination of features among metatherians and other South American mammals of Palaeogene age, including the well-known faunas of Patagonia. An analysis of its phylogenetic affinities suggests that Fieratherium is the sister-group of the Paucituberculata. As already described by other authors for several mammalian taxa, the mainly Patagonian South American Palaeogene fossil record offers little information to understanding the evolution of northern lineages. Fieratherium may represent a taxon belonging to a lineage that had its origin in Neotropical regions, so far unrecorded in the southern region of South America. http://zoobank.org/urn:lsid:zoobank.org:pub:5F6D3A50-6345-4E66-BE3E-7FEF6CC66A9B
Cellulase Production from Treated Oil Palm Empty Fruit Bunch Degradation by Locally Isolated Thermobifida fusca

The aim of this research was to evaluate the production of cellulases from locally isolated bacteria, Thermobifida fusca, using thermal and chemical treated oil palm empty fruit bunch (OPEFB) as substrate in liquid-state fermentation (LSF). T. fusca was successfully isolated and was a dominant cellulase producer in OPEFB composting at the thermophilic stage. Analysis of the surface morphology of OPEFB samples using Scanning Electron Microscopy (SEM) showed that the most significant changes after the combination of thermal and chemical pretreatment was the removal of silica bodies, and this observation was supported by X-ray Diffraction analysis (XRD), Fourier Transform Infrared (FTIR), and Thermogravimetric analysis (TG) showing changes on the hemicelluloses, cellulose, and lignin structures throughout the pretreatment process. As a result of the pretreatment, higher cellulase production by T. fusca was obtained. The highest activity for CMCase, FPase, and β-glucosidase using optimally treated OPEFB were 0.24 U/mL, 0.34 U/mL, and 0.04 U/mL, respectively. Therefore, it can be suggested that the combination of chemical and thermal pretreatments enhances the degradation of OPEFB for subsequent use as fermentation substrate, contributing to a higher cellulases yield by T. fusca.
Diabetes management in the primary care setting: a comparison of physicians’ performance by gender

Abstract Background A major shift in the gender of the medical-doctor workforce is now underway, and all over the world it is expected that an average 65% of the medical workforce will be women by 2030. In addition, an aging population means that chronic diseases, such as diabetes, are becoming more prevalent and the demand for care is rising. There is growing evidence of female physicians performing better than male physicians. Aim Our study aimed to investigate whether any differences in diabetes process indicators are associated with gender, and/or the interaction between gender and different organizational models. Design and setting A population-based cross-sectional analysis was conducted on a large data set obtained by processing the public health administration databases of seven Italian local health units (LHUs). The seven LHUs, distributed all over the Italian peninsula in seven different regions, took part in a national project called MEDINA, with the focus on chronic disease management in primary care (PC). Methods A total score was calculated for the average performance in the previously listed five indicators, representing global adherence to a quality management of patients with diabetes. A multilevel analysis was applied to see how LHUs affected the outcome. A quantile regression model was also fitted. Results Our study included 2287 Italian general practitioners (586 of them female) caring for a total of 2 646 059 patients. Analyzing the performance scores confirmed that female general practitioners obtained better results than males. The differences between males and females were stronger on the 25th and 75th percentiles of the score than on the median values. The interaction between gender and LHU was not significant. Conclusion Our study evidenced that female physicians perform better than males in providing PC for diabetes independently by the different organizational models. Further research to understand the reasons for these gender differences is needed.
Web forum crawling using text-based filters

Forum websites contain very valuable information about frequently occurred problems in any subject. The good thing about these forums is, it is organized in a very proper format so that people can navigate easily to their expected discussion page. Now a days search engines are becoming very specific for different types of websites. So, they are making special crawlers for different types of websites to crawl exact information from raw html code. The research on forum crawlers is increased since last few years. But the main challenge in forum crawlers is finding similarity between URLs from different forum sites. This paper focuses on crawling forum URLs and classifying them as Entry, Index, Thread and Page Flipping URLs.
Effect of oligofructose-enriched inulin on bone metabolism in girls with low calcium intakes

In the present clinical study, the effect of oligofructose-enriched inulin was studied on bone metabolism in girls from 9 to 12 years old, with low habitual calcium intakes, who attended public schools. Two calcium-enriched formulations, supplemented with oligofructose-enriched inulin (test drink) or without (standard drink) were made. Sixty pre-pubertal girls were randomized into a double-blind and crossover design, divided into three groups and received one daily portion of either the standard drink (group 1) or test drink (group 2) during 11 weeks, followed by a three-week washout period. Group control did not receive any supplementation. Biochemical evaluations of serum calcium, intact parathyroid hormone - iPTH - and bone alkaline phosphatase - BAP - were performed at baseline and after 4, 8 and 11 weeks of each intervention period. In group 1, a significant increase in serum calcium and BAP and a reduction of iPTH were observed after consumption of the test drink.
A Mathematical Model for the Transient Stability Analysis of a Simultaneous AC–DC Power Transmission System

The outcome of recent numerical simulation shows that the conversion of an AC transmission line to a simultaneous AC–DC line improves the system stability. This paper presents a mathematical model, suitable for the stability analysis of a simultaneous AC–DC transmission system, transmitting both AC and DC powers simultaneously through an existing AC line. The model is based on the principle of equal area criterion. The salient feature of this model is the introduction of a solution technique of an integral component of the model, which avoids the trial and error approach for the analysis. The model development process considers a single machine-infinite bus system with a transmission line connecting the machine and the infinite bus. The process also considers the severe most fault at the sending end bus. The validation of the model is executed through two different approaches; comparison of the results obtained applying the proposed model to the power system with the published ones in the literature and with the results obtained using standard software, MATLAB–Simulink, based circuit simulations. The model is also applied to a realistic system and IEEE benchmark systems to verify its capability of evaluating the benefits of a simultaneous AC–DC transmission system.
Survey Study on the Prevalence of Cutaneous Leishmaniasis in Iraq

Human cutaneous leishmaniasis (CL) is caused by Leishmania sp. parasite and endemic in Iraq. The current study was including analysis of available database from Iraqi CDC to determine the distribution of CL cases for the period (2008-2015 years) in Iraq. Total reported cases for this period were 17001 (range 2.9-10.5 per 100,000 individuals). Highest reported cases were recorded in the year 2015 (4000 cases). Male infections cases of CL (50.8%) were more than female infections (49.2%). Highest infections of CL were observed in the age group (5-14yr.) as (34.6%), While the lowest infection of CL were observed in the age group (>1yr.) as (4.3%). Highest infection case of CL was observed in the middle and west of Iraq (53%). In contrast, the lowest reported cases of CL were observed in the North of Iraq (1%). Monthly distribution of CL in winter was more than in summer months. This study concluded that the CL cases in continuously increasing. The aim of the study is to monitor the causes of CL distribution in Iraq.
A generalized Turán problem in random graphs

We study a generalization of the Turán problem in random graphs. Given graphs T and H, let ex(G(n,p),T,H) be the largest number of copies of T in an H‐free subgraph of G(n,p). We study the threshold phenomena arising in the evolution of the typical value of this random variable, for every H and every 2‐balanced T. Our results in the case when m2(H) > m2(T) are a natural generalization of the Erdős‐Stone theorem for G(n,p), proved several years ago by Conlon‐Gowers and Schacht; the case T = Km was previously resolved by Alon, Kostochka, and Shikhelman. The case when m2(H) ≤ m2(T) exhibits a more complex behavior. Here, the location(s) of the (possibly multiple) threshold(s) are determined by densities of various coverings of H with copies of T and the typical value(s) of ex(G(n,p),T,H) are given by solutions to deterministic hypergraph Turán‐type problems that we are unable to solve in full generality.