Miracle-dz/UniFAR-FTUs huggingface dataset:
Fatal Diabetic Ketosis

Three cases of Reiter's disease with aortic incompetence are described. The aortic lesion is believed to have developed during the course of Reiter's disease. This complication appears to be unusual, as no similar cases have been reported in the literature. A fourth patient, a woman with iritis, transient arthritis, cervicitis, and aortic incompetence, came to necropsy and is also recorded, though the diagnosis of Reiter's disease could not be made with certainty. A characteristic feature of the electrocardiogram was a prolonged P-R interval present at some time in all our patients.
EFFECT OF CHEMICAL AGENTS ON SOME ENZYME ACTIVITIES AND ON THE STABILITY OF MEMBRANE STRUCTURES

The effects of two chemical agents − sodium nitrite and phenobarbital (PB) applied separately or in combination, on the activity of enzymatic components of monooxigenase system of hepatocytes, the stability of liver lysosomes and peroxisomes as well as on the total activity of marker enzymes for these structures were investigated in male rats. Following the combined administration of both agents, the effects of sodium nitrite predominated. Nitrite eliminated at a considerable extent the membrane-stabilizing effect of the barbiturate, decreased its activating influence on aniline hydroxylase and potentiated PB-induced activation on systems catalyzing lipid peroxidation.
MODELING EXTRAGALACTIC JETS

▪ Abstract Extragalactic jets were discovered and initially studied by radio astronomers in connection with extended radio sources. At present, the combination of jets and disks is considered the crucial element in unification models for all active galactic nuclei (AGNs). The acceleration and propagation conditions of jets, together with the aspect ratio of the disk/jet geometry with respect to the observer, shape the morphologies of AGNs. However, these phenomenological models are very complex from the physical and mathematical point of view, as they involve different elements of the theories of gravitation, fluid dynamics, and electrodynamics in a highly nonlinear combination and in conditions not easily reproducible in laboratory plasma or fluid experiments. In the last ten years, theorists have attacked the subject with advanced analytical and numerical methods, and some important results have already been established that confirm the global scenario, although we are still far from a complete physical.
Public knowledge of and attitudes toward genetics and genetic testing.

BACKGROUND Variable health literacy and genetic knowledge may pose significant challenges to engaging the general public in personal genomics, specifically with respect to promoting risk comprehension and healthy behaviors. METHODS We are conducting a multistage study of individual responses to genomic risk information for Type 2 diabetes mellitus. A total of 300 individuals were recruited from the general public in Durham, North Carolina: 60% self-identified as White; 70% female; and 65% have a college degree. As part of the baseline survey, we assessed genetic knowledge and attitudes toward genetic testing. RESULTS Scores of factual knowledge of genetics ranged from 50% to 100% (average=84%), with significant differences in relation to racial groups, the education level, and age. Scores were significantly higher on questions pertaining to the inheritance and causes of disease (mean score 90%) compared to scientific questions (mean score 77.4%). Scores on the knowledge survey were significantly higher than scores from European populations. Participants' perceived knowledge of the social consequences of genetic testing was significantly lower than their perceived knowledge of the medical uses of testing. More than half agreed with the statement that testing may affect a person's ability to obtain health insurance (51.3%) and 16% were worried about the consequences of testing for chances of finding a job. CONCLUSIONS Despite the relatively high educational status and genetic knowledge of the study population, we find an imbalance of knowledge between scientific and medical concepts related to genetics as well as between the medical applications and societal consequences of testing, suggesting that more effort is needed to present the benefits, risks, and limitations of genetic testing, particularly, at the social and personal levels, to ensure informed decision making.
THE INNER KILOPARSEC OF Mrk 273 WITH KECK ADAPTIVE OPTICS

There is X-ray, optical, and mid-infrared imaging and spectroscopic evidence that the late-stage ultraluminous infrared galaxy merger Mrk 273 hosts a powerful active galactic nucleus (AGN). However, the exact location of the AGN and the nature of the nucleus have been difficult to determine due to dust obscuration and the limited wavelength coverage of available high-resolution data. Here we present near-infrared integral-field spectra and images of the nuclear region of Mrk 273 taken with OSIRIS and NIRC2 on the Keck II Telescope with laser guide star adaptive optics. We observe three spatially resolved components, and analyze the nuclear molecular and ionized gas emission lines and their kinematics. We confirm the presence of the hard X-ray AGN in the southwest nucleus. In the north nucleus, we find a strongly rotating gas disk whose kinematics indicate a central black hole of mass 1.04 ± 0.1 × 109 M☉. The H2 emission line shows an increase in velocity dispersion along the minor axis in both directions, and an increased flux with negative velocities in the southeast direction; this provides direct evidence for a collimated molecular outflow along the axis of rotation of the disk. The third spatially distinct component appears to the southeast, 640 and 750 pc from the north and southwest nuclei, respectively. This component is faint in continuum emission but shows several strong emission line features, including [Si vi] 1.964 μm which traces an extended coronal-line region. The geometry of the [Si vi] emission combined with shock models and energy arguments suggest that [Si vi] in the southeast component must be at least partly ionized by the SW AGN or a putative AGN in the northern disk, either through photoionization or through shock-heating from strong AGN- and circumnuclear-starburst-driven outflows. This lends support to a scenario in which Mrk 273 may be a dual AGN system.
2H-6 Tissue Doppler Gated (TDOG) Real-Time Stitching in Three-Dimensional Fetal Echocardiography

Three-dimensional (3D) fetal echocardiography is a promising technique for assessment of fetal cardiac structure and function, but suffers from lower temporal resolution than ultrasound imaging in two dimensions. Real-time, ECG-gated volume stitching is a known method in adult echocardiography, used to increase the spatial and/or temporal resolution of volumetric cardiac scans. In fetal echocardiography however, stitching has been impossible due to lack of ECG data for gating. A real-time gating signal for fetal echocardiography is suggested in this work. An ultrasound system was set up to acquire 3D gray-scale data and 3D tissue Doppler data simultaneously, with only the gray-scale data visible to the sonographer. Derived from the Doppler data, a gating signal, denoted the tissue Doppler gating (TDOG) signal, was calculated in real-time. The TDOG trigger events were used to induce changes in the geometry setup of the 3D gray-scale scan, ensuring that data from consecutive cardiac cycles were captured from separate parts of the total volumetric scan. A scan setup with six disjoint subvolumes was used, and the system could in real-time assemble and display volume data sets with data from the six most resent heart cycles. In-vivo data ware recorded from 5 pregnant women with fetuses aged 20-24 weeks, utilizing a matrix transducer with a center frequency of 3 MHz. TDOG signals from several different tissue Doppler scan geometries are presented: 5deg and 10deg planar sector scans and 8deg times 8deg volumetric scans. Volumetric, assembled scans acquired with TDOG gated stitching are shown, and both good and poor match between subvolumes are demonstrated. We conclude that the TDOG technique provides real-time gating of fetal cardiac cycles and it can be used to acquire stitched, 3D fetal echocardiographic data with high frame rate
An Efficient 2-Party Private Function Evaluation Protocol Based on Half Gates

Private function evaluation (PFE) is a special case of secure multi-party computation (MPC), where the function to be computed is known by only one party. PFE is useful in several real-life applications where an algorithm or a function itself needs to remain secret for reasons such as protecting intellectual property or security classification level. In this paper, we focus on improving 2-party PFE based on symmetric cryptographic primitives. In this respect, we look back at the seminal PFE framework presented by Mohassel and Sadeghian at Eurocrypt’13. We show how to adapt and utilize the well-known half gates garbling technique (Zahur et al., Eurocrypt’15) to their constant-round 2-party PFE scheme. Compared to their scheme, our resulting optimization significantly improves the efficiency of both the underlying Oblivious Evaluation of Extended Permutation (OEP) and secure 2-party computation (2PC) protocols, and yields a more than 40% reduction in overall communication cost (the computation time is also slightly decreased and the number of rounds remains unchanged).
Comparison of Ti-Based Coatings on Silicon Nanowires for Phosphopeptide Enrichment and Their Laser Assisted Desorption/Ionization Mass Spectrometry Detection

We created different TiO2-based coatings on silicon nanowires (SiNWs) by using either thermal metallization or atomic layer deposition (ALD). The fabricated surfaces were characterized by X-ray photoelectron spectroscopy (XPS), energy dispersive X-ray spectroscopy (EDX), and reflectivity measurements. Surfaces with different TiO2 based coating thicknesses were then used for phosphopeptide enrichment and subsequent detection by laser desorption/ionization mass spectrometry (LDI-MS). Results showed that the best enrichment and LDI-MS detection were obtained using the silicon nanowires covered with 10 nm of oxidized Ti deposited by means of thermal evaporation. This sample was also able to perform phosphopeptide enrichment and MS detection from serum.
Growth Phase Influences Complement Resistance of Bordetella pertussis

ABSTRACT The BrkA protein of Bordetella pertussis inhibits killing by the antibody-dependent classical pathway of complement; however, susceptibility to complement can be highly variable. Log-phase bacteria grown in Stainer-Scholte (SS) broth plated on Bordet-Gengou (BG) agar were about 500 times more sensitive to killing by complement than stationary-phase SS-BG cultures. While always more susceptible to complement than the wild-type strain, a BrkA mutant displayed a similar growth phase variation in susceptibility to complement. Growth phase susceptibility to complement was also observed for a mutant constitutive for Bvg activation of BrkA, suggesting that modulation of virulence factor expression was not responsible for sensitivity to complement. Susceptibility was not due to differential antigenic expression, since serum adsorbed with complement-resistant, stationary-phase SS-BG cultures lacked bactericidal activity against B. pertussis harvested at all times during the growth cycle. These results suggest that log-phase susceptibility to complement is not due to variable expression of BrkA or antigenic differences and may be an inherent property of rapidly growing cultures. Implications for vaccine development are discussed.
Short longitudinal versus transverse skin incision for carotid endarterectomy: impact on cranial and cervical nerve injuries and esthetic outcome.

AIM Nerve injuries, wound complications and especially poor cosmetic results still have an important impact on the carotid endarterectomy (CEA) morbidity. Introduction of the mini skin incision in clinical practice seems to be safe with reduction in postoperative pain and superficial and cranial nerves lesions, and better aesthetics outcomes. The objective of this retrospective study was to compare the results between the short longitudinal with the short transverse cervical incision and to evaluate their impact on cranial and cervical nerves and aesthetic outcomes. METHODS From January 2007 to December 2009 266 patients underwent 300 consecutive primary CEA procedures. Two-hundred nineteen patients were submitted to short longitudinal cervical incision (group A), in eighty one a short transverse cervical skin incision (group B) was performed. The average of skin incision was about 4-5.5 cm. In all cases a preoperative CEA duplex ultrasounds (US) assisted skin marking was carried out. All patients were submitted to the general anesthesia with Remifentanyl conserved consciousness. Routinely synthetic patch and selective policy intraluminal shunts were used. Incisions were extended when shunts were required or in case of high carotid bifurcation. Preoperative and postoperative cranial nerves evaluation was always performed and a questionnaire about the satisfaction of the aesthetic outcome was proposed to all patients to the discharge and six months follow-up. Stroke/TIA, death, wound complications, cranial and cervical nerves injuries and restenosis rate were reported and analyzed through statistical analysis (χ2 and Student's t test). RESULTS The 30 days mortality was 0.3% (1/300). The TIA rate was 0.91% in group A and 1.2 % in group B (P>0.9). Wound complications were 1.8% and 1.2 % respectively (P>0.1). No statistically differences were reported in the incidence of cranial and cervical nerves injuries between the two groups (P>0.9). No difference in restenosis rate was detected (P>0.9). In case of lengthening of the incision for high internal carotid (ICA) stenosis and especially to the need of shunt deployment, the longitudinal approach showed unequivocally to be easier and safer. CONCLUSION No differences were achieved between short longitudinal and transverse incision in term of stroke, wound complications or nerves impairment. A good cosmetic outcome was gained in both groups. The Duplex US skin markings pre-CEA permitted localization and limits of the plaque with appropriate short incision. A longitudinal cervical approach is to prefer as can lead to an easier proximal and distal lengthening in cases of atherosclerotic extension of the plaque and shunt deployment.
Social network analysis of students' participation and presence in a community of educational blogging

Purpose – The purpose of this paper is to report on an investigation of university students' participation and learning presence in a blogging activity, designed to support collaborative learning. There are three main reasons justifying the current research: to better understand the structure and the dynamics of students' blogging subgroups; to reveal students' patterns of engagement and their roles within the blogging community; and to evaluate the applicability of social network analysis (SNA) in studying students' performance and learning presence in educational blogs.Design/methodology/approach – The design of students' blogging activities was rooted on the ideas of authentic learning and followed a project‐based learning philosophy. Data analysis used methods of SNA to reveal collaborative aspects of students' engagement, the different roles undertaken by the students and the structure of the community within group blogs.Findings – SNA shed light into the different patterns of students' participation.
A Methodology for Estimating Instream Flow Values for Recreation

Water flowing in. streams has value for various types of recreationist s and is essent ial for fish and wildlife. Since water demands for offstream uses in the arid west have been steadily increasing, increasing instream flows to enhance the recreational experience might be in confl ict with established withdrawals for uses such as agricul ture, industries, and households. since market prices are not observable for instream flows, the estimation of economic value of instream flow would present well known difficulties. The household production function theory was used to build the theoretical model to measure economic value of instream flow. A representative sample of 500 recreationists at three river sites were interviewed during the summer of 1982, to estimate empirical demand equation for recreational activities. In order to estimate economic value of water used in the river, it was assumed that individuals were combining goods, services, and time as input to produce recreational services. Based on this procedure, empirical estimates of multisite demands were derived. Moreover, the corresponding I compensat ing variations I of consumers, from alteration of instream flow, were quantified.
Myopia in Singapore kindergarten children.

PURPOSE The purpose of this study was to examine whether close-up work was related to myopia in Singapore kindergarten children. METHODS One hundred twenty-eight children, ages 3 to 7 years, from a kindergarten in Singapore were examined by cycloplegic autorefraction. The parents also completed a questionnaire on the different types of close-up work activities each child was engaged in, socioeconomic status, and parental history of myopia. RESULTS Myopic children spent 3.0 hours per day (median) on close-up work activity, while nonmyopic children spent 2.0 hours per day (median) on close-up work activity. The prevalence of myopia in the sample was 8.6%. CONCLUSION Close-up work activity was not related to myopia in pre-school children.
Everolimus, an mTOR pathway inhibitor, is highly successful on ovarian hyperstimulation syndrome by reducing ovarian weight and progesterone levels: a preclinical experimental randomized controlled study

Abstract The usefulness of various pathways inhibitors, Everolimus, an inhibitor of mammalian target of rapamycin (mTOR), Infliximab, a monoclonal antibody which blocks the tumor necrosis factor-a (TNF-a), Erlotinib, a tyrosine protein kinase inhibitor of the epidermal growth factor receptor (EGFR), Metformin, an activator of AMP-activated protein kinase enzyme (AMPK) and vascular permeability reducers were explored in an ovarian hyperstimulation syndrome (OHSS) rat model. Sixty-three female Wistar rats were randomly divided in seven groups. The control group received saline, while the OHSS group received recombinant -- follicle-stimulating hormone (rec-FSH) for four consecutive days. The other five groups received rec-FSH for 4 d and Everolimus daily, Infliximab once, Erlotinib daily, Metformin daily and Vitamin C daily, respectively. All groups received human chorionic gonadotropin (hCG) at the fifth day. The efficacy of Everolimus administration for various intervals was also explored. Significantly reduced ovarian weight was observed in the Everolimus group (rec-FSH + hCG + mTOR inhibitor) compared to the OHSS group (p < 0.001). The Everolimus group also showed the lowest progesterone (PRG) concentration (p = 0.007). The Erlotinib group (rec-FSH + hCG + EGFR inhibitor) presented with the lowest graafian follicle number, while the Everolimus group was characterized by the lowest corpus luteum number. The vascular permeability and the estradiol levels did not differ between groups. Finally, the Everolimus intra-comparison showed no difference in all measured outcomes. Studying the different pathways linked to vascular endothelial growth factor (VEGF) pathway, we conclude that targeting mTOR pathways is beneficial for reducing ovarian weight and PRG levels in an OHSS animal model. Chinese abstract 用于抑制各种通路的抑制剂依维莫司，一种哺乳动物雷帕霉素靶蛋白抑制剂(mTOR)，英夫利西，阻碍肿瘤坏死因子-α（TNF-α）的一种单克隆抗体，埃罗替尼，表皮生长因子(EGFR)的酪氨酸蛋白激酶受体抑制剂，二甲双胍，腺苷酸活化蛋白激酶（AMPK）催化剂和血管通透性缩减剂被探索应用于卵巢过度刺激综合征（OHSS）的大鼠模型。 63只雌性wistar大鼠被随机分为7组 。 对照组使用生理盐水，OHSS组连续四天给予重组卵泡刺激素（rec-FSH）. 其余五组处理方式分别为给予rec-FSH 4天和依维莫司每日一次，英夫利西一次，埃罗替尼每日一次，二甲双胍每日一次和维生素C每日一次。 所有组别均在第五天给予人绒毛膜促性腺激素(hCG). 同时探究了在不同间期依维莫司处理的疗效。 依维莫司组（rec-FSH + hCG + mTOR 抑制剂）与OHSS组相比观察到了显著的卵巢重量降低（p<0.001）。 依维莫司组同时也表现出了最低的孕酮浓度 (p=0.007). 埃罗替尼组（rec-FSH + hCG + EGFR 抑制剂）格拉夫卵泡的数量最少，而依维莫司组以最少的黄体为特征。 血管通透性和雌二醇水平各组并无差异。 最后，依维莫司的组间比较表明所有数据均无差异。 根据对相关血管内皮生长因子通路相关不同通路的研究，我们推断靶向mTOR通路有利于减少OHSS模型动物的卵巢重量和PRG水平。
Undiagnosed breech

had been sufficiently deflated to pass through the incision. There is no need to extend the wound or to perform a colpotomy. The results of Yuen and Rogers (1993) compared well with Manyonda et al. (1993) and Nezhat et al. (1989). The average size of the dermoid cyst was 6 cm and the mean operative time was 72 minutes (range 60 to 90 minutes). The post-operative pain was minimal, and all patients were fit for discharge 48 hours after the operation. In experienced hands, laparoscopic removal of dermoid cysts is a safe and effective procedure. The use of Endopouch eliminates the risk of spillage and the need to extend the skin wound or perform colpotomy.
Effects of wheezing in early childhood in the development of allergic rhinitis in later years

Background Studies on the long-term effects of wheezing in infancy have particularly focused on asthma. There isn't adequate information about the effects of wheezing in the development of allergic rhinitis in later years. Objective In this study, children with wheezing in the first year of life were investigated in terms of allergic rhinitis after five years of age. Methods The study consisted of children with early-transient wheezing or persistent wheezing. The study groups were evaluated in terms of allergic rhinitis with physical examination and a questionnaire translated from International Study of Asthma and Allergies in Children (ISAAC) questionnaire after five years of age. Results The study included 50 children; 23 (46%) had early-transient wheezing and 27 (54%) had persistent wheezing. The symptoms of allergic rhinitis were reported in 13 (48%) of children with persistent wheezing but in none of children with early-transient wheezing (p < 0.05). Skin prick tests showed positive results in 4.3% of children with early-transient wheezing and in 48.1% of children with persistent wheezing (p < 0.05). Conclusion Persistent wheezing, but not early transient wheezing seems to be a risk factor in the development of allergic rhinitis in children after five years of age.
Early carotid angioplasty and stenting may offer non-inferior treatment for symptomatic cases of carotid artery stenosis

Objective Early intervention is desirable in patients presenting with stroke or transient ischemic attack (TIA) referable to carotid artery stenosis because of the high incidence of recurrent ischemic events within 48 h post-ictus. However, the optimal timing of performing carotid angioplasty and stenting (CAS) in these patients remains unclear amid concerns for an elevated risk of perioperative complications. The primary outcome of this study was the combined incidence of major perioperative complications (stroke, myocardial infarction (MI), death) based on timing of CAS relative to symptom onset. Methods A prospectively maintained database of all neuroendovascular procedures at our hospital was searched for consecutive cases of extracranial internal CAS procedures performed for symptomatic atherosclerotic carotid stenosis between January 2009 and January 2012. Rates of perioperative complications including 30-day stroke, MI and death were assembled in a total of 221 patients. Results The primary outcome was not statistically different among groups stratified based on intervention timing, with a combined incidence of stroke, MI or death of 7.1% in patients treated within 2 days, 4.5% in patients treated between days 3 and 7, 2.8% in patients treated between days 8 and 14 and 3.7% in patients treated between days 15 and 90 (p=0.749, Fisher exact test). Conclusions Our results support the conclusion that early CAS (within 2 days) carries no additional risks compared with CAS after 2 days or any other timing of the intervention up to 90 days. Early CAS may represent a reasonable option for acute revascularization to minimize the risk of perioperative stroke and overall perioperative complications.