Miracle-dz/UniFAR-FTUs huggingface dataset:
Leader trait learning goal orientation and employee voice behavior: the mediating role of managerial openness and the moderating role of felt obligation

Abstract We theorized and tested the process through which leader trait learning goal orientation influences employee voice behavior. Data were collected from 507 employees and 70 supervisors in a variety of companies in Southeast China. Results obtained from hierarchical linear modeling showed that leader trait learning goal orientation was significantly related to employee voice behavior, and that managerial openness mediated this relationship. Moreover, our cross-level interaction results showed that felt obligation for constructive change moderated the relationship between managerial openness and employee voice behavior, such that this relationship was positive only among employees with a high felt obligation for constructive change. The implications of our findings for the theory and practice of leadership and employee voice behavior are discussed here.
Interrelation of Hydration, Collagen Cross-Linking Treatment, and Biomechanical Properties of the Cornea

ABSTRACT Purpose: The present study was designed to investigate the effects of hydration and collagen cross-linking treatment on biomechanical properties of the cornea. Methods: The original corneal collagen cross-linking protocol was used to induce cross-links in bovine corneas. The thickness of samples was used as a measure of their hydration and five different thickness groups (n = 5 each) were considered. The cross-linked corneal strips were allowed to hydrate/dehydrate until their thickness reached 500, 700, 900, 1100, and 1500 μm. The tensile behavior of specimens in each thickness group was characterized by conducting uniaxial tensile experiments. The experiments were done in mineral oil in order to keep the thickness of samples constant and minimize hydration changes. Results: It was observed that collagen cross-linking treatment significantly increased both the maximum tensile stress and the equilibrium (relaxed) stress of the bovine cornea (p < 0.01). Furthermore, with increasing the thickness (hydration) of the collagen cross-linked samples, their tensile stiffness significantly decreased (p < 0.01). An exponential relation and a logarithmic expression successfully represented experimentally measured stress–strain behavior and relaxation response of all groups (r2 > 0.99), respectively. Conclusion: Hydration and collagen cross-linking treatment concomitantly affect biomechanical properties of the cornea. Therefore, an accurate estimate of stiffening effects of collagen cross-linking treatment option using uniaxial tensile experiments is only possible if the hydration of specimens is fully controlled.
The effectiveness of incentive spirometry with physical therapy for high-risk patients after coronary artery bypass surgery.

BACKGROUND AND PURPOSE The purpose of this study was to determine whether the addition of incentive spirometry (IS) to postoperative pulmonary physical therapy is more effective than physical therapy alone in reducing postoperative pulmonary complications in high-risk patients after coronary artery bypass grafting (CABG). Patients were given the spirometer and instructed in its use, as often occurs in clinical settings. SUBJECTS Patients with chronic airflow limitation following CABG (N = 185) participated. METHODS Subjects were randomly assigned to receive either postoperative pulmonary physical therapy (breathing exercises, secretion removal, mobility) or physical therapy combined with IS. RESULTS No difference was found between the two groups in atelectasis, spirometry, oxygen saturation, pulmonary infection, or hospital stay. CONCLUSION AND DISCUSSION Incentive spirometry combined with physical therapy is no more effective than postoperative physical therapy alone in reducing atelectasis for this population. Use of the spirometer, however, was not monitored, and although the study mimicked practice as it often occurs, the effectiveness of the spirometer cannot be fully evaluated.
Application of quintic order parabolic arcs in the analysis of waveguides with arbitrary cross-section

A simple and efficient higher order finite element scheme is presented for obtaining highly accurate numerical solution for the two-dimensional Helmholtz equation in waveguides of arbitrary cross-section subjected to dirichlet boundary conditions. The above approach makes use of the Quintic order (5th order) parabolic arcs for accurately mapping the irregular cross section of the waveguide and then transforming the entire waveguide geometry to a standard isosceles triangle. In case of waveguides with regular geometry the transformation is done by straight sided quintic order finite elements. A unique and accurate point transformation technique is developed that ensures high accuracy of mapping by this quintic order curved triangular elements. This point transformation procedure gives a simple interpolating polynomial that defines the transformation from the global coordinate system to the local coordinate system. The above higher order finite element method is found to be highly optimal and accurate considering the various computational parameters like the number of triangular elements, degrees of freedom, nodal point distribution on the entire geometry, etc.
Four-dimensional breast imaging, part II: clinical implementation and validation of a computer imaging system for breast augmentation planning.

BACKGROUND No publications exist describing the impact of three-dimensional imaging on the consultation process for breast augmentation, nor have existing software products claiming simulation features been validated. OBJECTIVES The authors describe the application of four-dimensional technology during patient consultation to assist in planning implant size and type. METHODS Forty-six primary breast augmentation patients underwent preoperative consultation with 4D simulation software; 35 out of 46 also received follow-up imaging. At six months postoperatively, simulated measurements were compared to actual measurements and questionnaires were mailed to patients asking them to assess the imaging experience. A follow-up phone survey 18 months postoperatively examined the persistence of patient attitudes about implant size and imaging. Practice productivity was evaluated by comparing specific parameters (such as scheduling rates) between three separate time periods for the same clinic. RESULTS Across all parameters, breast augmentation simulations correlated highly with positive surgical outcomes (R-value = 0.68). The majority (95%) of patients believed the simulations were accurate; 89% also expressed that it enhanced trust in the surgeon and 74% reporting that it helped in choosing an implant size. Despite 48% also indicating that they would select a larger implant if they were to undergo surgery again, no patients have undergone reoperations of any kind. Compared to historical controls, scheduling rates in the practice increased from 40% to 77% after addition of simulation software. CONCLUSIONS 4D breast imaging appears to be an accurate system for analysis, planning, simulation, and patient education for women considering primary breast augmentation, and application of this technology during the consultation process was correlated with a high degree of patient satisfaction and practice productivity.
Intracytoplasmic sperm injection in infertile patients with structural cytogenetic abnormalities.

OBJECTIVE To investigate the incidence of chromosomal aberration in men and women in an intracytoplasmic sperm injection (ICSI) program for severe male infertility as well as in conceptuses resulting from these ICSI treatments. STUDY DESIGN We evaluated chromosomal analysis, outcome of ICSI and the conceptuses resulting from treatment of 301 couples included in ICSI program. RESULTS Cytogenetic evaluation demonstrated structural anomalies in 11 cases (3.6%), 9 men (2.9%) and 2 women (0.7%), all consisting of balanced chromosomal translocations. There were no significant differences in the rates of developed embryos (44.2% versus 40.1%) in couples with abnormal (n = 11) and normal (n = 290) chromosomal analysis. Embryo transfer led to a similar number of newborns (15.3% versus 12.4%) per transferred embryos, without any correlation with parents' chromosomes. In 63 fetuses conceived from couples without chromosomal abnormalities, we observed one fetus affected by Patau syndrome (47,XY, + 13). Two of four (50%) fetuses conceived by couples with male balanced chromosomal defects were carriers of the chromosomal translocation inherited from their fathers. The two fetuses resulted in the birth of two infants observed to be normal at the 12-month pediatric follow-up. CONCLUSION The offer of this treatment to infertile couples with male factor infertility should be accompanied by proper information regarding the genetic risks of this treatment. ICSI remains a good therapeutic option for infertile patients, but prenatal diagnosis is mandatory because of the potential increased aneusomic risk for the offspring conceived.
LACK OF AN ASSOCIATION BETWEEN BMI AND TSH IN TREATED HYPOTHYROID PATIENTS AND EUTHYROID CONTROLS.

OBJECTIVE The standard treatment for primary hypothyroidism is replacement with levothyroxine to achieve a thyroid-stimulating hormone (TSH) level within the normal range, (0.45-4.5 mIU/L), which is known to prevent complications including weight gain. While the normal TSH range includes the 95% confidence intervals, it is not known if there is an association between weight and TSH within this interval in treated hypothyroid patients. METHODS We conducted a retrospective analysis of patients treated within the Cooper Health System from January 1 to August 31, 2014. A sample of 245 treated hypothyroid patients and 162 euthyroid controls were studied. Data collected included age, sex, race/ethnicity, height, weight, levothyroxine dose, and diabetes and smoking history. RESULTS Hypothyroid and control groups were similar in height, weight, body mass index (BMI), and the number of patients with diabetes. There were more females, Caucasians, and nonsmokers in the hypothyroid group. The average TSH was slightly higher in the treated hypothyroid patients versus nonhypothyroid controls (median 1.87 vs. 1.55, P<.01). There was no significant relationship between TSH and BMI in the treated hypothyroid patients or the euthyroid controls. CONCLUSION Since no significant relationship was found between BMI and TSH in treated hypothyroidism, there may be no weight reduction benefit gained by adjusting TSH to the lower end of normal range. Patients should be counseled that properly treated hypothyroidism is unlikely to contribute to weight gain. Other treatments such as nutrition and exercise counseling should be offered instead.
Coronary artery dissection during pregnancy and the postpartum period: Two case reports and review of literature

Spontaneous coronary dissection is a rare event occurring particularly in women during the peripartum and postpartum period. Two cases related to the early postpartum period with a successful outcome are described, together with a comprehensive review of all the previously published cases. Diagnostic and therapeutic considerations of this unique clinical entity are discussed and reviewed. Cathet Cardiovasc Intervent 2001;52:88–94. © 2001 Wiley‐Liss, Inc.
Mechanisms of early visual processing in the medulla of the locust optic lobe: How self-inhibition, spatial-pooling, and signal rectification contribute to the properties of transient cells

Abstract In the arthropod medulla, which is the second ganglion on the afferent visual pathway, a column of about 40 cells represents each point in space (i.e. compound eye facet). Some stages of visual processing underlying the responses of one class of cells in the locust medulla have been identified. These transient cells give very similar responses to intensity increments and decrements, and also to pulses and steps; there is no spontaneous activity and a stimulus causes one or two spikes to fire at fixed latencies. Movement, however, produces a prolonged spike discharge by successive excitation of subunits within the receptive field. One of the main features of the transient cells' responses is a self-inhibition which attenuates responses to successive stimuli at one point. This inhibition is restricted to the outputs of single receptor (rhabdom), it decays after about 100 ms, and is polarity sensitive so that stimuli of one polarity (e.g. dimming) do not inhibit responses to stimuli of the opposite polarity (e.g. brightening). The inhibition effectively alters the contrast threshold of the cells, because after adaptation with stimuli of one contrast, a modest (<20%) increase in contrast is sufficient to elicit an unadapted response. Transient cells are not directionally selective and there are no local spatio-temporal interactions of the kind necessary for directional selectivity. But, by analogy with the directional veto in directionally selective cells in the rabbit retina (Barlow & Levick, 1965), self-inhibition is suggested as a mechanism of non-directional motion detection. After the inhibition, there is some spatial pooling of signals which is followed by rectification. The transient cells' spiking outputs could abstract a refined subset of visual information which may encode the presence, but not the direction, amplitude, or polarity of moving object borders.
Acrodermatitis Continua of Hallopeau with Bone Resorption in an 8-Year-Old Patient: A Case Report

Acrodermatitis continua of Hallopeau (ACH) is an uncommon inflammatory disease manifesting as sterile pustular eruption of the fingers and toes. The disease is of a chronic relapsing nature and is often refractory to treatment. With longstanding disease, osteitis with consequent bone resorption of the underlying phalanges can occur, leading to disability. While the incidence of ACH is rare in children, complications like osteolysis have not been reported previously in this age group. In this paper, we report the case of an 8-year-old boy with severe ACH complicated by bone resorption.
Textural, Structural and Biological Evaluation of Hydroxyapatite Doped with Zinc at Low Concentrations

The present work was focused on the synthesis and characterization of hydroxyapatite doped with low concentrations of zinc (Zn:HAp) (0.01 < xZn < 0.05). The incorporation of low concentrations of Zn2+ ions in the hydroxyapatite (HAp) structure was achieved by co-precipitation method. The physico-chemical properties of the samples were characterized by X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), Scanning Electron Microscopy (SEM), zeta-potential, and DLS and N2-BET measurements. The results obtained by XRD and FTIR studies demonstrated that doping hydroxyapatite with low concentrations of zinc leads to the formation of a hexagonal structure with lattice parameters characteristic to hydroxyapatite. The XRD studies have also shown that the crystallite size and lattice parameters of the unit cell depend on the substitutions of Ca2+ with Zn2+ in the apatitic structure. Moreover, the FTIR analysis revealed that the water content increases with the increase of zinc concentration. Furthermore, the Energy Dispersive X-ray Analysis (EDAX) and XPS analyses showed that the elements Ca, P, O, and Zn were found in all the Zn:HAp samples suggesting that the synthesized materials were zinc doped hydroxyapatite, Ca10−xZnx(PO4)6(OH), with 0.01 ≤ xZn ≤ 0.05. Antimicrobial assays on Staphylococcus aureus and Escherichia coli bacterial strains and HepG2 cell viability assay were carried out.
Cartilage status in FAI patients – results from the Danish Hip Arthroscopy Registry (DHAR)

Introduction: The femoroacetabular impingement (FAI) morphology is associated with specific cartilage lesions, which are suspected to be early stages of the osteoarthritic development, which can be the end result of FAI. The cartilage status of FAI afflicted hip joints at the time of arthroscopic management is not fully elucidated. This study from the Danish Hip Arthroscopy Registry (DHAR) will try to show data on the cartilage status from a large cohort. Data from a national registry potentially represent large amounts of population-based epidemiological information from multiple centres and surgeons. Therefore, outcome data might be more reliable for a specific surgical intervention. Methods: This study includes patients operated for symptomatic FAI from January 2012 until December 31st 2013, with a minimum of two-year follow-up and being registered in DHAR. The extent of cartilage damage at the time of surgery is reported and the Patient Related Outcome Measures (PROM) outcome data are presented. Results: Data from a total of 686 FAI procedures in 1082 patients from January 2012 until December 31st 2013 were extracted from DHAR. Cartilage injuries were found in 88% of cases, mainly on the acetabular side. Overall PROM including pain scores improved significantly from preoperative status to follow-up one and two years postoperatively. The Copenhagen Hip and Groin Outcome Score (HAGOS), Hip Sports Activity Scale (HSAS) and global hip function showed less improvements in patients with more severe acetabular cartilage injury. Discussion: The majority of patients with femoroacetabular impingement (FAI) undergoing hip arthroscopy have significant cartilage changes at the time of surgery primarily at the acetabulum and to a lesser degree at the femoral head. During FAI surgery the majority of patients have cartilage debridement performed but rarely cartilage repair. The presence of severe cartilage injury at the time of arthroscopic FAI surgery results in reduced subjective outcome and hip function.
Reminiscence and dementia: a therapeutic intervention

ABSTRACT Background: Dementia is a significant public health problem. One non-pharmacological therapy that has shown its effectiveness is reminiscence, which is a psychological intervention designed to address issues of particular relevance to older adults. The aim of this study was to examine the benefits of an integrative reminiscence program in elderly people with dementia. Methods: A quasi-experimental design and purposeful sampling were conducted at two retirement homes. Forty-two elderly adults with dementia were studied to measure the effect of the therapy (23 in the experimental group and 19 in the control group). The treatment group activity was held in 10 sessions. Results: The treatment group significantly improved their depressive symptoms and self-acceptance, positive relations with others, autonomy, and environmental mastery. Conclusions: This study provides support for the effectiveness of integrative reminiscence therapy (RT) as an intervention in people with dementia, especially in reducing depressive symptoms and improving psychological well-being, with the therapy being effective on personal and emotional variables.
A study of principals’ perceptions as implementers of Michigan’s mandated teacher evaluation policy

The purpose of this study was to identify and develop an understanding of the relationships between the perceptions of principals regarding the Michigan mandatory annual teacher evaluation policy and job satisfaction, self-efficacy, and stress as principals navigated the roles of building manager, instructional leader and policy implementer. This quantitative study asked 3,009 Michigan public school principals to share their perceptions regarding the teacher evaluation policy. A total of 426 principals responded to a questionnaire published in a web-based format using a Likert scale. Interest in this study by the Michigan Department of Education Research Department allowed access to all email addresses for Michigan public schools using the Educational Entity Master (EEM) system. Questions in the survey collected demographic data and uncovered perceptions held by respondents regarding policy implementation, role definition, and reinforced constructs of job satisfaction, self-efficacy, time, stress, need for training and fairness in the implementation process Stakeholder theory, which had roots in business, defined the reciprocal relationship between owners and stakeholders by observing management practices implemented for the pursuit of articulated organizational goals and served as the conceptual framework. Descriptive and inferential statistics were used for the analysis and showed Michigan principals were marginally knowledgeable regarding the requirements of the evaluation policy; job satisfaction and self-efficacy were correlated to principals’ voice in the formation and implementation of the evaluation policy especially at the building and district levels; a weak relationship existed between knowledge and respondent self-esteem; and the constructs of job satisfaction, self efficacy, stress/time and knowledge were predictors for successful
Identification of a Functional Homolog of the Mammalian CYP 3 A 4 in Locusts Line

Insects have been proposed as a new tool in early drug development. It was recently demonstrated that locusts have an efflux transporter localized in the blood-brain barrier (BBB) that is functionally similar to the mammalian P-glycoprotein efflux transporter. Two insect BBB models have been put forward, an ex vivo model and an in vivo model. To use the in vivo model it is necessary to fully characterize the locust as an entire organism with regards to metabolic pathways and excretion rate. In the present study, we have characterized the locust metabolism of terfenadine, a compound that in humans is specific to the cytochrome P450 enzyme 3A4. Using high-resolution mass spectrometry coupled to ultra-high-performance liquid chromatography, we have detected metabolites identical to human metabolites of terfenadine. The formation of human metabolites in locusts was inhibited by ketoconazole, a mammalian CYP3A4 inhibitor, suggesting that the enzyme responsible for the human metabolite formation in locusts is functionally similar to human CYP3A4. Besides the human metabolites of terfenadine, additional metabolites were formed in locusts. These were tentatively identified as phosphate and glucose conjugates. In conclusion, not only may locusts be a model useful for determining BBB permeation, but possibly insects could be used in metabolism investigation. However, extensive characterization of the insect model is necessary to determine its
Genetic Diversity of Cultivated Lentil (Lens culinaris Medik.) and Its Relation to the World's Agro-ecological Zones

Assessment of genetic diversity and population structure of germplasm collections plays a critical role in supporting conservation and crop genetic enhancement strategies. We used a cultivated lentil (Lens culinaris Medik.) collection consisting of 352 accessions originating from 54 diverse countries to estimate genetic diversity and genetic structure using 1194 polymorphic single nucleotide polymorphism (SNP) markers which span the lentil genome. Using principal coordinate analysis, population structure analysis and UPGMA cluster analysis, the accessions were categorized into three major groups that prominently reflected geographical origin (world's agro-ecological zones). The three clusters complemented the origins, pedigrees, and breeding histories of the germplasm. The three groups were (a) South Asia (sub-tropical savannah), (b) Mediterranean, and (c) northern temperate. Based on the results from this study, it is also clear that breeding programs still have considerable genetic diversity to mine within the cultivated lentil, as surveyed South Asian and Canadian germplasm revealed narrow genetic diversity.