Miracle-dz/UniFAR-FTUs huggingface dataset:
Prolonged Armed Conflict and Diminished Deference to the Military: Lessons from Israel

We examine whether the level of deference shown by the Israeli Supreme Court to military decisions has changed over time by empirically analyzing the entire body of Supreme Court decisions in petitions against the military commander between 1990 and 2005. Setting forth a number of different factors that might generally affect the degree of deference to state agencies, we hypothesized that there would be a decrease in deference in the relationship between the Court and the military commander during the examined period. Our findings show that deference to the military commander has indeed diminished significantly. We argue that this is best explained by the continuation of the armed conflict (and its aftermath, namely, the routinization and increase in the number of petitions by the civilian population) and also—to some extent—by the rise of a substantive rule‐of‐law legal consciousness, central to which is the importance of human rights.
Advances in Wine Aging Technologies for Enhancing Wine Quality and Accelerating Wine Aging Process

Wine aging is an important process to produce high-quality wines. Traditionally, wines are aged in oak barrel aging systems. However, due to the disadvantages of the traditional aging technology, such as lengthy time needed, high cost, etc., innovative aging technologies have been developed. These technologies involve aging wines using wood fragments, application of micro-oxygenation, aging on lees, or application of some physical methods. Moreover, wine bottling can be regarded as the second phase of wine aging and is essential for most wines. Each technology can benefit the aging process from different aspects. Traditional oak barrel aging technology is the oldest and widely accepted technology. The application of wood fragments and physical methods are promising in accelerating aging process artificially, while application of micro-oxygenation and lees is reliable to improve wine quality. This paper reviews recent developments of the wine aging technologies. The impacts of operational parameters of each technology on wine quality during aging are analyzed, and comparisons among these aging technologies are made. In addition, several strategies to produce high-quality wines in a short aging period are also proposed.
Benzalkonium chloride in nasal decongestive sprays has a long‐lasting adverse effect on the nasal mucosa of healthy volunteers

Twenty healthy volunteers participated in the present study on the long‐term effects of a nasal decongestive spray composed of either a combination of oxymetazoline nasal spray and benzalkonium chloride or of oxymetazoline nasal spray alone. Three months before the present study the participants had undergone treatment with nasal decongestants for 4 weeks. Ten of the subjects had been treated with oxymetazoline nasal spray without bezalkonium chloride and 10 of them had been treated with oxymetazoline nasal spray with benzalkonium chloride. In a double‐blind study the subjects who had been treated with oxymetazoline nasal spray and benzalkonium chloride were again treated with the same combination of substances as before, and the subjects who had been treated with oxymetazoline nasal spray alone were also treated again with oxymetazoline nasal spray alone, but on this occasion only for 10 days. Three variables were studied before and after the 10 days of treatment, i.e. nasal mucosa congestion, nasal reactivity and symptom scores. It was found that only the subjects who were treated with the combination of oxymetazoline nasal spray and benzalkonium chloride had increased nasal stuffiness, estimated by symptom scores and measurements of nasal mucosa swelling after 10 days of treatment. It is concluded that a nasal decongestant spray composed of a combination of vasoactive substance and benzalkonium chloride has a long‐term adverse effect on the nasal mucosa.
ADHD With Comorbid Oppositional Defiant Disorder or Conduct Disorder

Objective: In children with ADHD who have comorbid disruptive behavior diagnoses distinctions between oppositional defiant disorder (ODD) and conduct disorder (CD) remain unclear. The authors investigate differences between ODD and CD in a large clinical sample of children with ADHD. Method: Consecutively referred and systematically assessed male children and adolescents with either ADHD (n = 65), ADHD with ODD (n = 85), or ADHD with CD (n = 50) were compared using structured diagnostic interviews and parent, teacher, and clinician rating scales. Results: In children with ADHD, significant differences emerged between ODD and CD in the domains of delinquency, overt aggression, and ADHD symptom severity; ADHD with CD was most severe, followed by ADHD with ODD, and ADHD had the least severe symptoms. Distinctions between ADHD with CD and the other two groups were found for parenting, treatment history, and school variables. Conclusion: Within the limits of a cross-sectional methodology, results support clinically meaningful distinctions between ODD and CD in children with ADHD. (J. of Att. Dis. 2008; 12(2) 126-134)
Acute Effects of Static vs. Ballistic Stretching on Strength and Muscular Fatigue Between Ballet Dancers and Resistance-Trained Women

Abstract Lima, CD, Brown, LE, Wong, MA, Leyva, WD, Pinto, RS, Cadore, EL, and Ruas, CV. Acute effects of static vs. ballistic stretching on strength and muscular fatigue between ballet dancers and resistance-trained women. J Strength Cond Res 30(11): 3220–3227, 2016—Stretching is used to increase joint range of motion, but the acute effects can decrease muscle strength. However, this may depend on the population or mode of stretching. The purpose of this study was to compare the acute effects of static vs. ballistic stretching on strength and muscular fatigue between ballet dancers and resistance-trained women. Fifteen resistance-trained women (age 23.8 ± 1.80 years, mass 67.47 ± 7.77 kg, height 168.30 ± 5.53 cm) and 12 ballet dancers (age 22.8 ± 3.04 years, mass 58.67 ± 5.65 kg, height 168.00 ± 7.69 cm) performed 5 days of testing. The first day was control (no stretching), whereas the other 4 days were static or ballistic stretching in a counterbalanced order. Range of motion, strength, and fatigue tests were also performed. Both groups demonstrated a significant decrease in hamstrings strength after static (102.71 ± 2.67 N·m) and ballistic stretching (99.49 ± 2.61 N·m) compared with control (113.059 ± 3.25 N·m), with no changes in quadriceps strength. For fatigue, only ballet dancers demonstrated a decrease from control (71.79 ± 4.88%) to ballistic (65.65 ± 8.19%), but no difference with static (65.01 ± 12.29%). These findings suggest that stretching decreases hamstrings strength similarly in ballet dancers and resistance-trained women, with no differences between modes of stretching. However, ballistic stretching only decreased muscular fatigue in ballet dancers, but not in resistance-trained women. Therefore, no stretching should be performed before strength performance. However, ballistic stretching may decrease acute muscular fatigue in ballet dancers.
Is Low Dialysate Potassium Ever Indicated in Outpatient Hemodialysis?

Maintenance of potassium (K) homeostasis is a critical element of the dialysis prescription. Potassium removal in any given dialysis treatment is dependent on the dialysate potassium concentration (KD) and the predialysis serum potassium; almost half is removed from the extracellular space (1). This involves removal of supra-physiological quantities of potassium in a very short time interval from the extracellular space with subsequent equilibration via transcellular shift over subsequent hours (2). This electrolyte shift may predispose to cardiac electrical instability, a concern supported by a number of studies that have evaluated the role of KD concentration and the risk of cardiac arrhythmias and sudden cardiac death. The incidence of sudden cardiac arrest at hemodialysis is estimated to range from 4.5 to 7 per 100,000 sessions, suggesting about 2700–4200 sudden cardiac arrests at dialysis in the United States per year. Most hemodialysis treatments are performed using a KD < 3 mEq/l. Data from the Dialysis Outcomes and Practice Patterns Study (DOPPS) between 1996 and 2008 from 12 countries indicated that of 37,765 study participants, 29,629 (78.4%) were dialyzed against a low KD (<3 mEq/l) (3). Similarly, a study of 56,984 maintenance HD patients in the United States between 2001 and 2004 found that at least 78% of maintenance hemodialysis patients were on a low K bath (4), while 46% of incident dialysis patients in Alberta (Canada) between 2001 and 2006 were on a low K bath (5).
Enteroviruses and Bacteriophages in Bathing Waters

ABSTRACT A new procedure for detecting and counting enteroviruses based on the VIRADEN method applied to 10 liters of seawater was examined. It improved the efficiency of detection by taking into account both the number of positive isolations and numbers found with traditional methods. It was then used to quantify viruses in bathing waters. A number of bacterial indicators and bacteriophages were also tested. Cultivable enteroviruses were detected in 55% of the samples, most of which complied with bacteriological criteria. In contrast, viral genomes were only detected in 20% of the samples by reverse transcription-PCR. Somatic coliphages outnumbered all other indicators. F-specific RNA phages were detected in only 15% of the samples, whereas phages infecting Bacteroides thetaiotaomicron were detected in 70% of samples. A numerical relationship between the numbers of enteroviruses and the numbers of enterococci and somatic coliphages was observed. In situ inactivation experiments showed that viruses persisted significantly longer than the bacterial indicators. Only somatic coliphages and bacteriophages infecting Bacteroides persisted longer than the viruses. These results explain the numbers of enteroviruses and indicators in bathing waters attending the numbers usually found in sewage in the area. Somatic coliphages show a very good potential to predict the risk of viruses being present in bathing waters.
Calcinosis circumscripta involving the metatarsal region in a dog with chronic renal failure.

Athree-year-old intact female German Shepherd dog was referred to the Purdue University Veterinary Teaching Hospital for examination of a mass involving the soft tissues of the left lateral metatarsal area. The history was unremarkable. The cutaneous mass was firm with an ulcerated, exudative surface and measured 6 x 4 x 2 cm. Other findings on physical examination included small stature, poor body condition, and poor quality hair coat. The kidneys, as assessed by palpation, were small. A complete blood count, serum biochemical analysis, and urinalysis was performed. A nonregenerative anemia (PVC 0.30 L/L) and lymphopenia (0.820 x 109/L) were present. Azotemia (serum urea nitrogen 38.6 mmol/L and creatinine 1644.2 /Amol/L), hyperphosphatemia (3.6 mmol/L), hypercalcemia (3.28 mmol/L), and mild hyperamylasemia (1,236 IU/L) were present as well as mild hypokalemia (4.0 mmol/L) and hypochloremia (112.0 mmol/L). Urine was isosthenuric (1.010) with an inactive urine sediment, and urine culture produced no bacterial growth. Radiographs of the left metatarsus showed a multilobular, mineralized cutaneous mass that did not involve the local osseous structures or pad. Thoracic radiographs revealed a slight increase in interstitial pattern and mineralization of the major lobar bronchi. The kidneys were not visible on abdominal radiographs due to lack of contrast. Ultrasonographic evaluation revealed hyperechoic kidneys with thin cortices and dilated pelves. Histological evaluation of a biopsy of the cutaneous mass revealed cystic structures that contained granular basophilic material surrounded by multinucleated giant cells, macrophages, and lymphocytes. Fibrous connective tissue was present between the cysts. A diagnosis of calcinosis circumscripta and chronic renal failure was made. The owner chose not to pursue any further
Invasive and non-invasive long-term mechanical ventilation in Italian children.

BACKGROUND To date, few studies have been published regarding the number of children in Italy who require long-term mechanical ventilation (LTV) and their underlying diagnoses, ventilatory needs and hospital discharge rate. METHODS A preliminary national postal survey was conducted and identified 535 children from 57 centers. Detailed data were then obtained for 378 children from 30 centers. RESULTS The estimated prevalence in Italy of this population was 4.3/100000. The majority of children (72.2%) were followed in pediatric units. The primary physicians who cared for these patients were either pediatric intensivists or pediatric pulmonologists. Neurological patients (78.2% of cases) represented the principal disorder category. 57.2% of the patients were non-invasively ventilated, with a nasal mask being the most common interface (85% of cases). The presence of clinical symptoms that were associated with abnormal findings on diagnostic testing was the primary indication for ventilatory support, whereas weaning failure was the primary indication for tracheotomy. Invasive ventilation was significantly related to younger age, longer daily hours on ventilation and cerebral palsy. Ventilatory modes with guaranteed minimal tidal volume were more often used in patients with tracheotomy. Despite their age, illness severity and need for technological care, 98% of the study population were successfully home discharged. CONCLUSION Managing pediatric home LTV requires tremendous effort on the part of the patient's family and places a significant strain on community financial resources. In particular, neurological patients require more health care than patients in other categories. To further improve the quality of care for these patients, it is essential to establish a dedicated national database.
Homozygote Depression in Gamete-Derived Dragon-Fruit (Hylocereus) Lines

Putative gamete-derived progenies from two Hylocereus species, the diploid H. monacanthus and the tetraploid H. megalanthus, were studied with the dual aims to confirm their gamete origin and to evaluate their potential use as genetic resources. An additional goal was to determine the origin (allotetraploid vs. autotetraploid) of H. megalanthus by exploring morphological variations in the di-haploid (2x) H. megalanthus progeny. Gamete origin was proved in all five H. monacanthus lines obtained and in 49 of the 70 H. megalanthus lines by using flow cytometry and simple sequence repeat (SSR) markers. The five double-haploid (2x) H. monacanthus lines showed low vigor and abnormal flower development, with malformed ovules and aborted pollen grains. Only one flower set fruit, giving several viable seeds. For H. megalanthus, both abnormal ovules and defective anthers were observed in the di-haploid (2x) and double di-haploid (4x) lines. Among the 46 di-haploid lines, only 14 set fruit. Another 13 di-haploid lines formed flower buds that abscised before anthesis or soon after pollination. The severe sterility of the double-haploid H. monacanthus and the reduced fertility of all the di-haploid and double di-haploid H. megalanthus lines can be linked to their reduced heterozygosity, which drastically affected the development of normal female and male organs. We thus concluded that chromosome doubling, as occurred spontaneously in the double-haploid H. monacanthus and the double di-haploid H. megalanthus, is not sufficient to restore fertility in Hylocereus. We also observed very low gametoclonal variation among the di-haploid (2x) H. megalanthus lines, a finding that supported an autotetraploid, rather than an allotetraploid, origin of this species. Nonetheless, despite the above-described challenging limitations, these gamete-derived lines are currently being bred as the seed parent, offering unique possibilities for genetic research and additional breeding.
A Moving Display Which Opposes Short-Range and Long-Range Signals

A novel display is described which stimulates both the long-range and the short-range motion detecting processes simultaneously, but with opposing directions of movement. The direction in which the stimulus appears to move depends on retinal eccentricity and element size, but adaptation to the display always produces a motion aftereffect (MAE) direction opposite to the direction of the short-range component. The display may offer insights into the properties of the two-process motion detecting system.
Hydrodynamic and statistical parameters of slug flow

In two-phase slug flow pattern, the bulk of the gas is trapped inside large bubbles that are separated by liquid slugs, which may contain small dispersed bubbles. The unsteady nature of slug flow makes the prediction of pressure drop and heat and mass transfer a difficult task. Earlier models that deal with steady slug flow assume constant lengths and shapes of liquid slugs and elongated bubbles, as well as a constant elongated bubble propagation velocity. However, due to the intrinsically irregular character of slug flow, statistical means are required for its proper description. Variation of the flow parameters along the pipes of various diameters and inclinations may strongly affect the resulting flow pattern and should thus be taken into account in modeling the flow. The development of slug flow along the pipe is mainly governed by the interaction between consecutive elongated bubbles
Accumulation of CD8+ T Cells in Advanced-Stage Tumors and Delay of Disease Progression following Secondary Immunization against an Immunorecessive Epitope1

Self-reactive T cells that survive the process of positive and negative selection during thymocyte development represent potential effector cells against tumors that express these same self-Ags. We have previously shown that CD8+ T lymphocytes (TCD8) specific for an immunorecessive epitope, designated epitope V, from the SV40 large T Ag (Tag) escape thymic deletion in line SV11 Tag-transgenic mice. In contrast, these mice are tolerant to the three most dominant Tag epitopes. The majority of the residual epitope V-specific TCD8 have a low avidity for the target epitope, but a prime/boost regimen can expand higher avidity clones in vivo. Whether higher avidity TCD8 targeting this epitope are affected by Tag-expressing tumors in the periphery or can be recruited for control of tumor progression remains unknown. In the current study, we determined the fate of naive TCR-transgenic TCD8 specific for Tag epitope V (TCR-V cells) following transfer into SV11 mice bearing advanced-stage choroid plexus tumors. The results indicate that TCR-V cells are rapidly triggered by the endogenous Tag and acquire effector function, but fail to accumulate within the tumors. Primary immunization enhanced TCR-V cell frequency in the periphery and promoted entry into the brain, but a subsequent booster immunization caused a dramatic accumulation of TCR-V T cells within the tumors and inhibited tumor progression. These results indicate that epitope V provides a target for CD8+ T cells against spontaneous tumors in vivo, and suggests that epitopes with similar properties can be harnessed for tumor immunotherapy.
Education-to-job mismatch and the risk of work injury

Objectives To examine the association between education-to-job mismatch and work injury. Methods Cross-sectional data from the 2003 and 2005 Canadian Community Health Surveys (n=63 462) were used to examine the relationship between having an educational level that is incongruent with occupational skills requirements and the risk of sustaining a work injury requiring medical attention or a work-related repetitive movement injury (RMI). The effect on injury of the interaction of overeducation with recent immigrant status was also examined. Models were stratified by sex and adjusted for possible confounders. Occupational physical demands were conceptualised as a potential mediating variable. Results After adjustment for covariates, over-education was associated with work injury and RMI for both sexes. Adjustment for occupational demands attenuated the impact on work injury but did not eliminate the effect on RMI among men. The interaction of over-education and recent immigrant status resulted among men in a fourfold increase in the odds of work injury compared with non-recent immigrants who were not over-educated. After adjustment for occupational demands, over-educated recent immigrant men still had more than a twofold increase in the odds of injury. Conclusions The risk of sustaining a work injury is higher among those whose education exceeds that of job requirements. These findings highlight the need to address barriers to suitable employment, particularly among recent immigrants.
Brain sites projecting to the spinal nucleus of the bulbocavernosus

Motoneurons of the spinal, nucleus of the bulbocavernosus (SNB) occupy a distinct dorsomedial position in the ventral horn of lumbar segments 5 and 6 and innervate sexually dimorphic striated muscles of the rat perineum, including the bulbocavernosus and levator ani. To begin the study of brain influences upon SNB function, we used retrograde tracers to identify brain regions that project to the area of SNB motoneurons. Our findings provide strong evidence that lateral vestibular and several reticular nuclei innervate the SNB. Additional possible afferents include the superior and medial vestibular nuclei raphe nucleus, red nucleus, interstitial nucleus of the medial longitudinal fasciculus, and paraventricular nucleus.
Corticonuclear projections of the cerebellum preserve both anteroposterior and mediolateral pairing patterns

The aim of the present study was to establish whether a diverging arrangement of the corticonuclear cerebellar projections exists and, if so, what relation it has with the inferior olivary complex. Iontophoretic injections of a 1 : 1 mixture of tetramethylrhodamine dextran amine and byotinilated dextran amine into the cerebellar cortex orthogradely labelled fibre terminals in the cerebellar nuclei and retrogradely labelled cell bodies in the inferior olivary complex. The injections were into A, B, C2, C3, D1 and D2 bands. These injections showed diverging projections to the cerebellar nuclei, with ‘primary projections’ directed to the nuclear region previously reported to be specifically connected with the injected band and ‘secondary projections’ directed to other nuclear regions. Secondary projections from the A, C2 and C3 bands diverged to nuclear regions primarily controlled by cortical bands lateral to those injected. Secondary projections from the D1, and D2 bands diverged to nuclear regions primarily controlled by cortical bands medial to those injected. Moreover, injections distributed along the D1 and D2 bands showed similar sets of nuclear targets, while those distributed along the A, C2 and C3 bands showed two sets of nuclear targets in relation to the anteroposterior location of the injected area within these bands. The cortical areas that projected to the same set of nuclear targets were innervated from single olivary regions, while those that projected to different sets of nuclear targets were innervated from different subsets of single regions of the inferior olive. The results suggest that the olivary bands of the cerebellar cortex project to the cerebellar nuclei with a diverging pattern that is organized in both the mediolateral and the anteroposterior axes.