Miracle-dz/UniFAR-FTUs huggingface dataset:
The ambiguity of place branding consultancy: working with stakeholders in Rio de Janeiro

ABSTRACT This study explores the tensions inherent in place branding consulting, by problematising the prescriptive and functionalistic view of consultants that characterises the place branding literature. If consultants’ pervasive impact on the contemporary place branding practice cannot be ignored, their fixed representation as powerful agents of top-down policies might limit more holistic accounts of consultancy practice. Indeed, consultants can find themselves mediating between bottom-up and top-down approaches to place branding. Thus, they can decide to promote more inclusive activities that give voice to local communities, while simultaneously addressing the needs of urban elites that are likely to pay the consultancy bill. Liminality is suggested as an appropriate idea to challenge role fixity and appreciate the ambiguity of place branding consultancy. The study reports self-reflective accounts from a case study on Rio de Janeiro, where the first author was involved in a three-year activity of working with stakeholders to stimulate a more inclusive public debate on city-brand management. Charting, snowballing, coopting consultants, informal advising, feeding and scientific arming are the six types of consulting practices of stakeholder engagement that the study identifies in order to offering a more nuanced representation of place brand consulting.
PEMETAAN POTENSI BIOGAS DI KOTA METRO

Metro City is a developing city that attracts many new citizens to come and live in the city of Metro. It affects the density and population growth in the city of Metro so it boils down to the increasing need for energy for fuel such as gas and electricity needs. UU No. 33 of 2007 the government seeks to optimize the role of PEMDA and communities and academics to be able to take advantage of the various potential that may be developed in their respective city in meeting energy needs. The survey results show the picture that the city of Metro has potential in the utilization of biogas energy. The availability of this organic material is quite common in Metro city. But the availability of the material has not been classified in number and variety. For that, we need to do research in mapping biogas potential in every area in Metro city. The research method used is the method of documentation, observation, and interview. As for data analysis techniques, conducted qualitatively and quantitatively through the findings of observations in the form of descriptions, calculation analysis, and tabulation. The results obtained show that the North Metro sub-district has the highest potential for biogas development. The most common materials are animal waste derived from cow dung as much as 84% and biogas from plants that are from rice straw (54%) and Tahu/tempe processing waste (38%). Other organic ingredients found are chicken, goat, buffalo, and banana peels. This result shows that the biogas potency of Metro City is best developed that is through the use of cow dung
Long Range Prediction Makes Adaptive Modulation Feasible for Realistic Mobile Radio Channels

-Adaptive transmission techniques, such as adaptive modulation and coding, adaptive power control, adaptive transmitter diversity, etc., depend on the transmitter's ability to predict future behavior of the channel. Recently, we proposed a reliable long-range prediction algorithm for rapidly time variant fading channels. In this paper, we analyze the statistical behavior of the errors generated by this channel prediction method. We show that our prediction technique makes adaptive modulation feasible for a standard stationary fading channel model (Jakes model), a novel realistic physical channel model and measured data. In addition, we demonstrate that the nonstationarity of the realistic mobile radio channel limits performance of adaptive modulation as the prediction range increases.
The Effect of Leverage on Asset Sales between Financial Institutions

This paper analyzes how the leverage of financial institutions affects their demand for assets and the resulting value of transactions between financial institutions. The results show a positive relationship between buyer capital and the likelihood of buying assets, and between buyer capital and the value of the deal. That is, those institutions that are the least constrained in their ability to raise funding are those that demand assets and pay more for them. This result does not hold, however, for deposit-taking institutions that had access to several government programs designed to improve their liquidity position during the crisis of 2008.
Predictors of Survival After Surgical Treatment of Spinal Metastasis

BACKGROUND:Surgery for spinal metastasis is a palliative treatment aimed at improving patient quality of life by alleviating pain and reversing or delaying neurologic dysfunction, but with a mean survival time of less than 1 year and significant complication rates, appropriate patient selection is crucial. OBJECTIVE:To identify the most significant prognostic variables of survival after surgery for spinal metastasis. METHODS:Chart review was performed on 200 surgically treated spinal metastasis patients at Stanford Hospital between 1999 and 2009. Survival analysis was performed and variables entered into a Cox proportional hazards model to determine their significance. RESULTS:Median overall survival was 8.0 months, with a 30-day mortality rate of 3.0% and a 30-day complication rate of 34.0%. A Cox proportional hazards model showed radiosensitivity of the tumor (hazard ratio: 2.557, P < .001), preoperative ambulatory status (hazard ratio: 2.355, P = .0001), and Charlson Comorbidity Index (hazard ratio: 2.955, P < .01) to be significant predictors of survival. Breast cancer had the best prognosis (median survival, 27.1 months), whereas gastrointestinal tumors had the worst (median survival, 2.66 months). CONCLUSION:We identified the Charlson Comorbidity Index score as one of the strongest predictors of survival after surgery for spinal metastasis. We confirmed previous findings that radiosensitivity of the tumor and ambulatory status are significant predictors of survival.
CT scanning of the coronary arteries : How to do it and how to interpret it

APPLIED RADIOLOGY© www.appliedradiology. com October 2005 Coronary artery disease remains one of the leading killers in the western world. Given that many of those dying of coronary artery disease have no antecedent history and that a large percentage of cardiac catheter interventions do not involve therapy, there is clearly a role for noninvasive imaging. Alhough it certainly has benefits in other areas, the inspiration and development of multidetector-row computed tomography (MDCT) has largely been driven by an interest in developing such noninvasive coronary angiography. Fundamentally, cardiac imaging is a straightforward extension of the principles underpinning stationary vessel CT angiography (CTA), though the beating heart introduces some new issues for data acquisition and processing. Although the application of mechanical helical CT for coronary imaging as yet lacks definitive outcome and comparative data, it has nevertheless gained a degree of acceptance in daily cardiology and radiology practice. Like many rapidly developing imaging modalities, cardiac CT implementation appears unlikely to pause for the results of long-term, evidence-based data. With MDCT still in its infancy, there is no monopoly on the correct way to perform and interpret coronary artery CT at this time. This paper will review and illustrate one approach to the current techniques of coronary artery MDCT data acquisition, processing, and clinical application.
Effect of p62 on tau hyperphosphorylation in a rat model of Alzheimer's disease

Tau hyperphosphorylation is a main cause of neuronal loss in Alzheimer's disease, which can be caused by many factors, including oxidative stress. The multifunctional protein p62, which exists in neurofibrillary tangles and causes aggregation of hyperphosphorylated tau, not only serves as a receptor in selective autophagy, but also regulates oxidative stress. However, whether p62 participates in oxidative stress-induced tau hyperphosphorylation remains unclear. In this study, we produced an Alzheimer's disease rat model by injecting β-amyloid protein into the hippocampus and β-galactose intraperitoneally. Hematoxylin-eosin staining was used for morphological analysis of brain tissue, and western blotting, immunohistochemistry and reverse transcription-PCR were employed to study p62 and autophagy related proteins, antioxidant defense system kelch-like ECH-associated protein 1-NF-E2-related factor 2 related proteins and hyperphosphorylated tau, respectively. The number of neurons in the brain decreased in Alzheimer's disease rats, and the autophagy related proteins Atg12-Atg5, microtubule-associated protein 1 light chain 3-phosphatidylethanolamine and Beclin1 increased significantly, while p62 expression reduced. Expression of kelch-like ECH-associated protein 1 increased, NF-E2-related factor 2 protein and the downstream gene products of glutamate cysteine ligase catalytic subunit and glutamate cysteine ligase modulatory subunit decreased, and hyperphosphorylated tau increased. These findings demonstrate that autophagy levels increased and p62 levels decreased in the brains of Alzheimer's disease rats. Moreover, the anti-oxidative capability of the NF-E2-related factor 2-antioxidant response element pathway was decreased, which may be the cause of tau hyperphosphorylation in Alzheimer's disease brain tissue and the subsequent structural and functional damage to neurons.
A qualitative analysis of influences on recovery following a first episode of psychosis

Background: Understanding perceived influences on recovery following a first episode of psychosis could help improve services. Material: Thematic analysis was used to examine important influences on early recovery identified by 30 individuals receiving services in an early intervention programme. Discussion: Social support, medication, meaningful activities and lifestyle modification were identified as helpful, and stigma, substance abuse and medication side effects as harmful. Perceptions of benefits of social support and the negative effects of stigma were particularly prominent. Conclusions: Results suggest the importance of assistance with engagement in valued activities and relationships, and provision of messages of worth and hope for recovery.
Importance of Multidrug Efflux Pumps in the Antimicrobial Resistance Property of Clinical Multidrug-Resistant Isolates of Neisseria gonorrhoeae

ABSTRACT The contribution of drug efflux pumps in clinical isolates of Neisseria gonorrhoeae that express extensively drug-resistant or multidrug-resistant phenotypes has heretofore not been examined. Accordingly, we assessed the effect on antimicrobial resistance of loss of the three gonococcal efflux pumps associated with a known capacity to export antimicrobials (MtrC-MtrD-MtrE, MacA-MacB, and NorM) in such clinical isolates. We report that the MIC of several antimicrobials, including seven previously and currently recommended for treatment was significantly impacted.
Development and validation of diagnostic tools for adolescent chronic pain patients

Background. Pain perception is a central aspect of the multidimensional model of chronic pain. Up to now, validated measurement tools are lacking in the German language for measuring pain perception in adolescents. The aim of this study was to examine and adapt the well-established Pain Perception Scale for Adults by Geissner (SES) for use in adolescents with chronic pain to provide a measure for clinical diagnosis and evaluation of treatment effects. Material and methods. Principal component, reliability and item analyses were conducted on a sample with 139 adolescents. To test validity, age and sex effects, correlations with pain-related constructs, differences between treatment groups (inpatients vs outpatients) and concordance between adolescents and their parents were analysed. Results. Findings support a two-factor solution with one affective and one sensory factor; three additional sensory items were included in the final version. The scales show good internal consistency. Consistent with hypotheses, we found significant correlations with pain characteristics, emotional and cognitive variables as well as pain-related disability. Inpatients and outpatients show a significant difference in affective pain perception. Concordance between parents and adolescents was high. Conclusion. With this questionnaire, there is now a validated German assessment tool to measure pain perception in adolescents with chronic pain (Pain Perception Scale for Adolescents, SES-J). Due to its practicability, it is suitable for clinical application. DIAGNOSTIC TOOLS FOR ADOLESCENT CHRONIC PAIN PATIENTS 51 3.2 Tension-type headache or migraine? Adolescents’ pain descriptions are of little help. Wager, J., Hirschfeld, G. , & Zernikow, B. (2013). Headache, 53(2), 322-332. doi: 10.1111/j.15264610. 2012.02224. x.
Cranial muscles of the anurans leiopelma hochstetteri and ascaphus truei and the homologies of the mandibular adductors in lissamphibia and other gnathostomes

The frogs Ascaphus truei and Leiopelma hochstetteri are members of the most basal lineages of extant anurans. Their cranial muscles have not been previously described in full and are investigated here by dissection. Comparison of these taxa is used to review a controversy regarding the homologies of the jaw adductor muscles in Lissamphibia, to place these homologies in a wider gnathostome context, and to define features that may be useful for cladistic analysis of Anura. A new muscle is defined in Ascaphus and is designated m. levator anguli oris. The differences noted between Ascaphus and Leiopelma are in the penetration of the jaw adductor muscles by the mandibular nerve (V3). In the traditional view of this anatomy, the paths of the trigeminal nerve branches define homologous muscles. This scheme results in major differences among frogs, salamanders, and caecilians. The alternative view is that the topology of origins, insertions, and fiber directions are defining features, and the nerves penetrate the muscle mass in a variable way. The results given here support the latter view. A new model is proposed for Lissamphibia, whereby the adductor posterior (levator articularis) is a separate entity, and the rest of the adductor mass is configured around it as a folded sheet. This hypothesis is examined in other gnathostomes, including coelacanth and lungfish, and a possible sequence for the evolution of the jaw muscles is demonstrated. In this system, the main jaw adductor in teleost fish is not considered homologous with that of tetrapods. This hypothesis is consistent with available data on the domain of expression of the homeobox gene engrailed 2, which has previously not been considered indicative of homology. Terminology is discussed, and “adductor mandibulae” is preferred to “levator mandibulae” to align with usage in other gnathostomes. J. Morphol. , 2011. © 2011 Wiley‐Liss, Inc.
Ca 2 +-H + antiport activity in synaptic vesicles isolated from sheep brain cortex

Synaptic vesicles isolated from sheep brain cortex exhibit an ATP-dependent Ca accumulation that is inhibited by the protonophore uncoupler carbonyl cyanide m-chorophenylhydrazone (CCCP) and completely released by the Ca ionophore ionomycin. This transport activity was sensitive to the V-type ATPase inhibitor, bafilomycin, but not to the P-type ATPase inhibitor, vanadate. We also observed that the proton gradient, established across the synaptic vesicle membranes in the presence of ATP, is partially dissipated by the addition of Ca (100–860 mM) in correlation to an increase of ATP hydrolysis by the H-pumping ATPase. In contrast, the activity of the H-ATPase, measured under uncoupling conditions (presence of CCCP), appears to be unaltered by the calcium ion. The Ca-induced H release visualized by fluorescence quenching of acridine orange correlates well with the Ca uptake determined isotopically. These results indicate that synaptic vesicles accumulate Ca, via a low affinity Ca–H antiport system energized by the protonmotive force originated from the H-pumping ATPase activity.  1998 Elsevier Science Ireland Ltd.
Role of Community Radio for Community Development in Bangladesh

Community radio is a medium of expressing and sharing views, thoughts, ideas, problems and prospects of rural, disadvantaged, vulnerable and hard to reach population with the mainstream population. As the media of root level people of the disadvantaged areas, Community radio has become popular in recent years and it has opened a new arena for both the policy makers as well as grassroots people to be involved in the development process of their community. There are about 17 Community Radios broadcasting 135 hours programmes in a day across the country. The Community Radio can help us in addressing social, economic, cultural, educational, health, water and sanitation and disaster related issues more effectively and strategically. In order to highlight the importance and effectiveness of community radio for the community development of Bangladesh, this study has been conducted based on the secondary data. This is a group effort that has become successful by the co-operation of many individuals and institutions. Access to Information (a2i) Programme would like to express sincere gratitude to Monisha Mohonto, Project Focal and Bakul Mohonto, Program Assistant, BTV for introducing such an innovative project. As this is a new concept, there is no significant study has been conducted. Therefore the study has been directed to explore the importance of community FM radio in Bangladesh particularly in remote and
Contribution of kinetic characteristics of axillary lymph nodes to the diagnosis in breast magnetic resonance imaging.

OBJECTIVE To assess the contribution of kinetic characteristics in the discrimination of malignant-benign axillary lymph nodes. MATERIAL AND METHODS One hundred fifty-five female patients were included in the study. Following magnetic resonance imaging (MRI) examinations postprocessing applications were applied, dynamic curves were obtained from subtracted images. Types of dynamic curves were correlated with histopathological results in malignant cases or final clinical results in patients with no evidence of malignancy. Sensitivity, specificity, positive likehood ratio (+LHR), negative (-LHR) of dynamic curves characterizing the axillary lymph nodes were calculated. RESULTS A total of 178 lymph nodes greater than 8 mm were evaluated in 113 patients. Forty-six lymph nodes in 24 cases had malignant axillary involvement. 132 lymph nodes in 89 patients with benign diagnosis were included in the study. The sensitivity of type 3 curve as an indicator of malignancy was calculated as 89%. However the specificity, +LHR, -LHR were calculated as 14%, 1.04, 0.76 respectively. CONCLUSION Since kinetic analysis of both benign and malignant axillary lymph nodes, rapid enhancement and washout (type 3) they cannot be used as a discriminator, unlike breast lesions. MRI, depending on the kinetic features of the axillary lymph nodes, is not high enough to be used in the clinical management of breast cancer patients.
Phenotypic sensitivity to activated protein C in healthy families: importance of genetic components and environmental factors

The relative importance of environmental factors and genetic components other than factor V Leiden on the sensitivity to activated protein C (APC) in healthy nuclear families was determined. We studied 149 European families (298 parents and 278 biological offspring aged more than 6 years). APC response was measured and expressed as normalized APC‐sensitivity ratio (n‐APC‐SR). Subjects were genotyped for G1691A and G20210A polymorphisms of factor V and II genes; levels of factors II, V and VIII, antithrombin, cholesterol, high‐density lipoprotein cholesterol and triglycerides were measured. After identifying variables influencing the n‐APC‐SR by a stepwise multiple regression model, variance component analysis was used. The heritability (proportion of the overall variability of a trait due to polygenic effects) of n‐APC‐SR was determined after adjustment for all clinical and laboratory variables, including factor V Leiden. Heritability coefficients (mean ± standard deviation) were different for males (0·68 ± 0·06) and females (0·34 ± 0·12) younger than 25 years and in subjects older than 25 years: 0·37 ± 0·09. This analysis provides strong evidence for a polygenic component influencing n‐APC‐SR in addition to factor V Leiden and suggests age‐ and gender‐specific genetic effects.
Intrauterine Inhibition of Prostaglandin Transporter Protein Blocks Release of Luteolytic PGF2alpha Pulses Without Suppressing Endometrial Expression of Estradiol or Oxytocin Receptor in Ruminants1

ABSTRACT In ruminants, prostaglandin F2 alpha (PGF2alpha) is synthesized and released in a pulsatile pattern from the endometria luminal epithelial (LE) cells during the process of luteolysis. Prostaglandin transporter (PGT) is a 12-transmembrane solute carrier organic anion transporter protein that facilitates transport of PGF2alpha. The present study determined the effects of inhibition of PGT protein on pulsatile release of luteolytic PGF2alpha and the underlined cell-signaling mechanisms. The results indicate that intrauterine inhibition of the PGT protein inhibits the pulsatile release of PGF2alpha from the endometrium and maintains a functional corpus luteum. Surprisingly, inhibition of PGT-mediated luteolytic pulses is not associated with spatial regulation of estrogen and oxytocin receptors in the LE of the endometrium and is also not accompanied by decreased biosynthesis of PGF2alpha or increased catabolism of PGF2alpha by the endometrium. Importantly, PGT inhibitor increases expression of pERK1/2 proteins in the LE of the endometrium. Knock down of ERK1/2 genes in LE cells reverses the inhibitory effects of PGT inhibitor on release of PGF2alpha. In conclusion, intrauterine inhibition of PGT inhibits the pulsatile release of PGF2alpha from the endometrium without modulating spatial expressions of estrogen and oxytocin receptor proteins and metabolism of PGF2alpha at the time of luteolysis. Activation of ERK1/2 pathways and interactions between ERK1/2 and PGT protein appear to be important cell-signaling mechanisms that control PGT-mediated efflux transport function. PGT emerges as an important final component in the luteolytic machinery that controls the release of luteolytic pulses of PGF2alpha from the endometrium in sheep.
Tourism management and subnational borders under Australian federalism : cross-border tourism management episodes in the Australian central east coast border region

Using a social constructionist approach, this thesis investigates the opportunities and challenges for cross-border tourism collaboration in an Australian subnational border region. It contributes a perspective wherein subnational border regions are characterised by multiple borders, networks, scales, meanings of borders and views on tourism. Existing approaches to investigating cross-border tourism management have focused on a single scale and on the integration of administrative units of government. Acknowledging the complexity of tourism management in subnational border regions, this thesis recommends new policy approaches and governance arrangements for sustainable cross-border tourism management.