Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparison of the Effect of Manual and Ventilator Hyperinflation on Static Lung Compliance in Mechanically Ventilated Patients with Pulmonary Acute Lung Injury/ ARDS

Purpose: Application of recruitment maneuvers, manual hyperinflation (MHI) and ventilator hyperinflation (VHI) in patients with acute lung injury/adult respiratory distress syndrome (ALI/ARDS) is controversial and concept of more recruitable lung volume in patients with extra-pulmonary ALI/ARDS has also been contradicted. The purpose of the study was to compare effectiveness of MHI and VHI in terms of improving static lung compliance (C ST ) and oxygenation (pulse oximetric saturation/ fraction of inspired oxygen ratio; S/F ratio), altering mean arterial blood pressure(MABP) and heart rate (HR) in patients with pulmonary ALI/ARDS (ALI/ARDSp). Methods: Randomized cross-over study involving 54 mechanically ventilated patients, clinically diagnosed with pulmonary ALI/ARDS. Results: Analysis of variance showed that there was highly significant improvement in CST values with both techniques (p 0.05) were statistically non-significant. Also, the two interventions did not show any adverse changes in blood pressure and heart rate. Conclusion: Hyperinflation as a part of physiotherapy treatment in mechanically ventilated patients with ALI/ARDSp can be performed with equal benefit with both techniques. Patients with ALI/ARDSp also have potential for lung recruitment.
Chapter 2 Typical Facial Beauty Analysis

As an interdisciplinary research topic facial beauty can be investigated understood from many aspects. An important issue is to determine features closely associated with facial beauty. In this book after introducing conventional features for facial beauty analysis we also present typical facial beauty analysis methods. The literature shows that researchers favor different methods. Some researchers believe that facial beauty underlies in the golden ratio. Some are interested in the averageness symmetry hypotheses. Recently biometrics techniques are also utilized for facial beauty analysis. This chapter gives a review of the typical facial beauty analysis methods discusses the advantages limitations of them. After reading this chapter people can have preliminary knowledge on features methods for facial beauty analysis. With this knowledge people will easily understand the following chapters.
Rotation invariant texture classification algorithm based on Curvelet transform and SVM

A rotation invariant texture classification algorithm based on curvelet transform and support vector machines (SVM) is proposed. The multidirectional and multiscale curvelet transform can offer more texture information and its energies are more compact as well as the SVM can achieve better classification. Compute the energies of the subbands acquired by curvelet transform to texture image first, then extract the rotation invariant feature vectors of isotropic, anisotropic and circular shift. The SVM algorithm is used to the texture classification at last. This method is compared with other rotation invariant texture classification algorithm, the experiment results show that it can improve the classification rate effectively.
Health Disparities in Colorectal Cancer Screening in the United States : An Application of the Social Ecological Model

Colorectal cancer (CRC) is the third most common cancer in the United States, yet the screening rate remains extremely low among certain populations, thereby making colorectal cancer screening an important and urgent public health issue. While it is well known among medical practitioners that CRC is almost 100% preventable if screened for and caught early, there exist significant racial, ethnic, socioeconomic, educational, and regional disparities with regard to those populations who are screened for CRC early and often, and those for whom are not. This paper draws upon the social ecological perspective to evaluate these social inequities in the US healthcare system and focuses primarily on the intersection between individual and ecological factors in the screening factors to identify possible interventions against unhealthy behaviours associated with CRC (i.e., neglecting to be screened).
The Effect of Permanent Income on Completed Schooling in Australia

Child poverty is a concern to any society, and the link between childhood poverty and schooling completion is one of the key factors causing cycles of intergenerational poverty in Australia. In particular, the literature suggests that it is sustained, or permanent, low income which has the most serious and long-lasting consequences on children, rather than transitory income shocks. This paper investigates the effect of permanent income during childhood on adolescent's schooling completion using the first six Waves of the HILDA Survey. The results show that whilst permanent income during adolescence is positively associated with the probability of completing Year 12 or a trade qualification, other factors including parental education and neighbourhood characteristics, have a far greater impact on adolescent's schooling preferences.
Inhibition of Translation by UAUUUAU and UAUUUUUAU Motifs of the AU-rich RNA Instability Element in the HPV-1 Late 3′ Untranslated Region*

The human papillomavirus type 1 (HPV-1) late mRNAs contain a 57-nucleotide adenosine- and uridine-rich RNA instability element termed h1ARE in their late 3′ untranslated regions. Here we show that five sequence motifs in the h1ARE (named I–V) affect the mRNA half-life in an additive manner. The minimal inhibitory sequence in motifs I and II was mapped to UAUUUAU, and the minimal inhibitory sequence in motifs III–V was mapped to UAUUUUUAU. We also provide evidence that the same motifs in the AU-RNA instability element inhibit mRNA translation, an effect that was entirely dependent on the presence of a poly(A) tail on the mRNA. Additional experiments demonstrated that the h1ARE interacted directly with the poly(A)-binding protein, suggesting that the h1ARE inhibits translation by interfering with the function of the poly(A)-binding protein.
Internationalization Strategy Based on Path Dependence Theory : Literature Review and Future Prospect

Although there are many kinds of literature on the internationalization of enterprises and strategic path dependence research were reviewed, there are no scholars on the path dependence theory perspective of the enterprise international strategy research specifically reviewed. In this paper, the literature review method is used to review the literature on the international strategic path of enterprises. First of all, the focus of combing the relevant literature involved in the concept, characteristics, the origin and development of the theory. Then, this paper introduces some scholars’ related discussions on the internationalization path dependence of enterprises. Finally, on the basis of these, the future direction of the research on the path dependence of the internationalization of enterprises is put forward from the aspects of cognitive perspective, dynamic capability theory and theoretical framework.
Isolation of a novel population of multipotent stem cells from epidermal layer of human skin

Fore skin samples were collected after surgical excision from boys below 7 years of age from Deccan Medical College –Hyderabad, in cold saline (4 0 C) in sterile containers. These skin samples were cut into small pieces and incubated in trypsinised phosphate buffer saline (PBS) overnight to dissociate epidermis from the dermis. The epidermal layer which got detached was lifted and taken for preparing the cell suspension. Viability of cells was 88% with PI staining. About 50 µl of cell suspension was aliquoted into vials (10 5 cells/per vial ) and incubated with 2 µl of the antibodies. Various biomarkers of stem cells such as CD34 – one of the marker’s of skin stem cell, CD 49f & CD29 - common stem cell markers, CD45 Lymphocytic marker, CD90 (Thy-1) skin stem cell marker and CD105 endothelial marker and CD56 (NCAM) neural adherent marker were used . Using these cell surface markers of stem cells, cytometry was performed on a FACS Calibur with sorter (BD Biosciences). These immunophenotypic markers with Cellquest software expressed the stem cells characteristics. FACS analyses gave different profiles of stem cells /progenitors of mesenchymal, hematopoietic and neural progenitors. These expressed profiles indicated that its progenitor might have the multipotent and or pluripotent character. By using embryonic markers, we could select a population of stem cells to give multipotent or pluripotent cells that could have the capacity to regenerate skin cells for application in burn cases, wounds, deep burns and non-healing wounds. In conclusion, we present here for the first time the isolation of pluripotent / multipotent skin stem cells from human foreskin biopsy samples and its potential applications for various applications.
Targeting DNA Checkpoint Kinases in Cancer Therapy

The DNA damage response includes not only cell cycle arrest and apoptosis, but also direct activation of DNA repair networks. Four DNA checkpoint kinases ATM, ATR, Chk1 and Chk2 have been identified in the mammalian DNA damage response signal transduction pathway. In this article, we review and discuss current knowledge and thinking about checkpoint kinases, and their potential as cancer drug targets. Particular emphasis is given to various therapeutic hypotheses and their promise for improving current cancer therapies.
Antenatal Indomethacin‐Adverse Fetal Effects Confirmed

Summary: We examined the association between antenatal indomethacin exposure and adverse neonatal outcome in a matched retrospective cohort study of infants born to 72 mothers at less than 31 weeks' gestation. Indomethacin‐exposed mothers were matched to controls by gestational age at delivery, antenatal corticosteroid exposure, prolonged spontaneous rupture of membranes, multiple pregnancy, thyrotrophin‐releasing hormone (TRH) exposure, and neonatal sex. Peri ventricular haemorrhage was significantly increased for infants delivered within 48 hours of maternal indomethacin exposure (Grade 1 and 2 19% versus 6%, and Grades 3 and 4 28% versus 3% (p<0.03)). Persistent patent ductus arteriosus was more common in those infants delivered within 48 hours of maternal indomethacin exposure (40% versus 20% (p<0.04)). More neonates exposed to antenatal indomethacin failed to respond to postnatal indomethacin to close a patent ductus arteriosus, 60% versus 0% (p<0.04). There were no adverse effects demonstrated of indomethacin administered greater than 48 hours from delivery. We have confirmed a probable association between antenatal indomethacin administration and an increased incidence of neonatal periventricular haemorrhage, patent ductus arteriosus, and impaired renal function. The adverse neonatal effects appear to be greatest when indomethacin is administered within 48 hours of delivery. We recommend that indomethacin should be used with caution as a tocolytic agent for the treatment of preterm labour at gestations less than 31 weeks.
Pseudomonas putida Strains Which Constitutively Overexpress Mercury Resistance for Biodetoxification of Organomercurial Pollutants

Improved biocatalysts for mercury (Hg) remediation were generated by random mutagenesis of Pseudomonas putida with a minitransposon containing merTPAB, the structural genes specifying organomercury resistance. Subsequent selection for derivatives exhibiting elevated resistance levels to phenylmercury allowed the isolation of strains that constitutively express merTPAB at high levels, conferring the ability to cleave Hg from an organic moiety and reduce the freed Hg(II) to the less toxic elemental form, Hg0, at greater rates. Constitutive overexpression of merTPAB had no apparent effect on culture growth rates, even when Hg(II) was initially present at otherwise toxic concentrations. These properties were also combined with benzene and toluene catabolism, allowing detoxification of the metal component of phenyl mercuric acetate, as well as degradation of its aromatic moiety.
Cross-sectional variations of illiquidity on stock returns , idiosyncratic volatility biases in the Chinese stock market

Under the NTS Reform (Non-tradable Share Reform), this paper explores the cross-sectional relations between illiquidity and stock returns by considering the idiosyncratic volatility biases in the Chinese stock market. To this end, we propose a new illiquidity index that measures the liquidity of the Chinese stock market more precisely than indexes used in previous studies. Differing from prior studies, stock returns are decreasing in a stock’s illiquidity both before and after the NTS Reform. Regarding the negative relation between illiquidity and stock returns, we find that stock returns show no clear relation with illiquidity after controlling for idiosyncratic volatility biases. Furthermore, we use residual approach to eliminate the effect of idiosyncratic volatility, and find there exists a positive relation between illiquidity and stock returns, especially after the NTS Reform. JEL codes: G11, G12, G15
OTDM Demultiplexing using HNLF in a NOLM at 160 Gb / s

We report all-optical demultiplexing using a Highly Nonlinear Fiber (HNLF) in a Nonlinear Optical Loop Mirror (NOLM). The NOLM uses Cross Phase-Modulation (XPM) between co-propagating control and signal pulses to switch the signal pulse from one output arm to the other. Simulations in combination with experiments show that this is a promising method for demultiplexing a single channel at a base rate of 10 or 40 Gb/s out of the 160 Gb/s Optical Time Division Multiplexed (OTDM) signal. A switching window of about 2.2 ps is measured with a control pulse of about 1.5 ps Full Width Half Maximum (FWHM).
Motivation , Disciplined Behaviour , Equal Treatment And Dispositional Flow In Physical Education Students

The purpose of this study is to analyse the possible relations between dispositional goal orientations, perceived motivational climate, discipline, coeducation and the flow state in physical education students. The sample consists of 1,103 students with an average age of 14. The results show that task orientation is related to discipline, the perception of equal treatment, the task-involving motivational climate, ego orientation and the flow state in a positive and significant manner, while it is related to indiscipline and the ego-involving motivational climate in a negative manner. On the other hand, ego orientation is related to indiscipline, the perception of discrimination, the ego-involving motivational climate, task orientation and the flow state in a positive and significant manner and to discipline, the perception of equal treatment and the taskinvolving motivational climate in a negative manner. In the multiple regression analysis we can observe how discipline is predicted by task orientation and by the perception of a task-involving motivational climate. The taskand ego-involving climate, as well as ego orientation, predict indiscipline. On the other hand, the perception of equal treatment is predicted by the task-involving climate. The ego-involving climate and ego orientation predict the perception of discrimination. Key-words: discipline, physical education, motivational climate, gender equality, dispositional flow. • University of Murcia, morenomu@um.es •• Research Department of Physical Education and Sports, University of Murcia ••• Catholic University of San Antonio of Murcia •••• Miguel Hernández University of Elche ••••• University of Castilla La Mancha
CHAPTER 4 Mead Production : Tradition Versus Modernity

Honey is a natural product with recognized physical and chemical properties, which contribute to its biological activity. However, honey is currently being sold at low prices, making it imperative to find alternatives to make apiculture a viable national enterprise. One of these alternatives could be mead production. Advances in Food and Nutrition Research, Volume 63 # 2011 Elsevier Inc. ISSN 1043-4526, DOI: 10.1016/B978-0-12-384927-4.00004-X All rights reserved. * CIMO, School of Agriculture, Polytechnic Institute of Bragança, Campus de Santa Apolónia, Bragança, Portugal { School of Agriculture, Polytechnic Institute of Bragança, Campus de Santa Apolónia, Bragança, Portugal 1 Corresponding author: Elsa Ramalhosa, E-mail address: elsa@ipb.pt
Experimental Study on the Use of Basalt Aggregate in Concrete Mixes

The purpose of this paper is to investigate the feasibility of using basalt aggregates in concrete mixes. Concrete is the most important engineering material and the addition or replacement of some of the materials may change the properties of the concrete. In recent years a lot of research work has been carried out in order to obtain more durable and long term performance of concrete structures in the dynamic environment. An experimental program is set up to test the effect of basalt aggregate content and its combinations with lime stone with variation of percentages in concrete mixes. Different aggregate percentage combinations were used in this study for basalt and limestone (0%,100%),(25%,75%),(50%,50%),(75%,25%),(100 %,0%) respectively. The laboratory investigation included measurement of compressive strength and workability. In addition the source aggregate properties were considered in this study: Los Angeles abrasion, specific gravity and absorption for coarse aggregates and fine aggregate. The result of this investigation indicate a general improvement in mix properties with the introduction of basalt aggregates in the mix. ’
A Study of Cardiac Autonomic Neuropathy in Patients with Type 2 Diabetes Mellitus: A Northeast India Experience

Aim: To investigate the prevalence and the risk factors for cardiac autonomic neuropathy (CAN) in type 2 diabetes mellitus (DM) patients. Study Design: Cross-sectional cohort study. Place and Duration of Study: This study was conducted in the Department of Endocrinology, Gauhati Medical College and Hospital, Assam, India between December 2016 to March 2018. Methodology: We included 100 patients (60 males and 40 females; age range: 36–72 years) with type 2 DM. Their clinical, biochemical, and metabolic parameters were analyzed and assessment of CAN were done based on the Ewing's criteria. Results: Out of 100 patients, 60 were males and 40 were females. The mean age of the patients was 53.3 ± 10.37 years (36–72 years) and the mean duration of diabetes was 9.03 ± 6.4 years (6 months–25 years). Patients were divided into two groups: “without CAN” (CAN−) and “with CAN” (CAN+). The prevalence of CAN was 70%, with early CAN in 25%, definite CAN in 24%, and severe CAN in 21% cases The patients with CAN were older (P = 0.0005), had longer diabetes duration (11.56 vs. 3.13; P = 0.0001), higher creatinine (P < 0.0001), and lower estimated glomerular filtration rate (eGFR) (P = 0.0001) compared to patients without CAN. Retinopathy, peripheral neuropathy, and nephropathy were common in CAN + patients. On multiple logistic regression analysis, duration of diabetes [odds ratio (OR); 6.7, P < 0.0001), older age (OR; 1.07, P < 0.016), and lower eGFR (OR; 0.97, P < 0.03) were risk factors for CAN. Conclusion: CAN is a common microvascular complication in type 2 DM with duration of diabetes, age, and severity of nephropathy being its significant determinants.
Mapping of the structural gene of pseudorabies virus glycoprotein A and identification of two non-glycosylated precursor polypeptides

Cell-free translation of pseudorabies virus RNA isolated during the late phase of the infectious cycle yielded a variety of polypeptides. A monoclonal antibody directed against one of the major viral glycoproteins, gA, immunoprecipitated two polypeptides ranging in molecular weight from 78K to 83K. To localize the structural gene for gA, we used cloned BamHI fragments of the viral DNA to select specific mRNA species and immunoprecipitated their in vitro translation products with the anti-gA monoclonal antibody. This allowed us to map the genomic region encoding the mRNA for the gA within the short unique region of the viral genome on BamHI fragments 7 and 12. Additional polypeptides encoded by this region were characterized by their electrophoretic mobility. In three virus strains tested a similar, but strain-specific, pattern of the two gA precursors was found which was not dependent on the host cell or the state of infection after reaching the late phase.
Heritability of pre–adult viability differences can explain apparent heritability of sperm displacement ability in Drosophila melanogaster

Sperm displacement has been the subject of a large number of evolutionary studies because of its effects on relative male reproductive success. To understand better the evolutionary role of variation in sperm displacement ability (SDA), an obvious aim is to measure its heritability. In this paper, we show that a standard method used to measure the heritability of SDA can be misleading. First, we show that using conventional methods (based on counts of adult offspring of multiply mated females), SDA appears to be heritable. However, an examination of potentially confounding variables strongly suggests that this result is misleading, and that the heritable component is more likely to be pre–adult viability. Consequently, it is likely that there is little measurable heritable genetic variation for SDA in D. melanogaster. We conclude that, although conventional methods of measuring sperm displacement will usually be adequate for phenotypic measurements, greater care must be taken when measuring genetic variances.
Detection of carbapenemase production in Enterobacteriaceae and Pseudomonas species by carbapenemase Nordmann–Poirel test

PURPOSE: Multidrug-resistant organisms causing community-acquired and hospital-acquired infections are increasing at a dangerous rate. Carbapenemase-producing Enterobacteriaceae and Pseudomonas species are an important source of concern since these organisms are not only resistant to beta-lactam antibiotics but also show cross-resistance to other groups of antibiotics. In the present study, rapid detection of these carbapenemase-producing Enterobacteriaceae and Pseudomonas species by carbapenemase Nordmann–Poirel (Carba NP) test was evaluated by comparing with modified Hodge test (MHT). MATERIALS AND METHODS: Imipenem-resistant Enterobacteriaceae and Pseudomonas species isolated from various samples such as pus, blood, sputum, urine, and endotracheal aspirates were processed for carbapenemase detection by MHT and Carba NP test. Kappa analysis was done to evaluate the percentage agreement between the two tests. RESULTS: Seventy imipenem-resistant Enterobacteriaceae and Pseudomonas isolates were analyzed in the present study for carbapenemase production. 63.41% of Enterobacteriaceae and 34.48% of Pseudomonas species were carbapenemase producers considering both the methods. By MHT, 36 (51.42%) isolates and, by Carba NP test, 35 (50%) isolates were positive for carbapenemase production out of the 70 isolates. CONCLUSION: Carba NP test when compared to MHT is a simple, rapid, cost-effective biochemical test which can be used in all laboratories in the identification of life-threatening carbapenemase-producing Gram-negative bacteria.