Miracle-dz/UniFAR-FTUs huggingface dataset:
Young children's difficulty with indirect speech acts: implications for questioning child witnesses.

Prior research suggests that infelicitous choice of questions can significantly underestimate children's actual abilities, independently of suggestiveness. One possibly difficult question type is indirect speech acts such as "Do you know. " questions (DYK, e.g., "Do you know where it happened? "). These questions directly ask if respondents know, while indirectly asking what respondents know. If respondents answer "yes," but fail to elaborate, they are either ignoring or failing to recognize the indirect question (known as pragmatic failure). Two studies examined the effect of indirect speech acts on maltreated and non-maltreated 2- to 7-year-olds' post-event interview responses. Children were read a story and later interviewed using DYK and Wh- questions. Additionally, children completed a series of executive functioning tasks. Both studies revealed that using DYK questions increased the chances of pragmatic failure, particularly for younger children and those with lower inhibitory control skills.
Morphology and Morphometry of Lingual Papillae in Adult and Newborn Egyptian Fruit Bats (Rousettus aegyptiacus)

The paper presents a comparison of the microscopic structure and morphometric traits of gustatory and mechanical lingual papillae in newborn and adult frugivorous Egyptian fruit bats (Rousettus aegyptiacus). All of the four types of lingual papillae found in adult animals were observed on the tongue surface in the newborn Egyptian fruit bats. After the birth, the gustatory papillae (fungiform and vallate papillae) were especially well‐developed, as their structural characteristics, such as morphology of the epithelium and presence of the taste buds, indicate that they have reached almost complete functional traits. Mechanical papillae, particularly filiform papillae, in newborns are still fetal in character. Keratinization processes in the epithelium of these papillae are not advanced and specific structures, such as elongated processes, are missing. The morphometric analysis of the size of papillae and thickness of the mucosal epithelium showed that a complete development of keratinized structures in Egyptian fruit bats occurs at later stages of postnatal development.
Wage Dispersion and Decentralization of Wage Bargaining

This article studies how decentralization of wage bargaining from sector to firm level influences wage levels and wage dispersion. We use detailed panel data covering a period of decentralization in the Danish labor market. The decentralization process provides variation in the individual worker’s wage-setting system that facilitates identification of the effects of decentralization. We find a wage premium associated with firm-level bargaining relative to sector-level bargaining and that the return to skills is higher under the more decentralized wage-setting systems. Using quantile regression, we also find that wages are more dispersed under firm-level bargaining compared to more centralized wage-setting systems.
The effect of cerclage in twin gestations with short cervix: a Bayesian evaluation

Abstract Objective: Bayesian inference allows the revision of prior clinical estimates of treatment effectiveness based on current data. We apply it to a published dataset evaluating the effect of cerclage upon preterm delivery in twin gestations with a short cervix. Study design: Prior probability distributions for delivery <35 weeks gestation for the control group and the treatment (cerclage) group were constructed under assumptions ranging from treatment having no effect (prior A) to halving early deliveries (prior C). Likelihood functions were calculated based on a published meta-analysis. Posterior probability densities were derived from which risk ratios for early delivery were computed, with 95% credible intervals and the probability of cerclage benefit. Results: Median posterior risk ratios (95% credible intervals) for delivery <35 weeks with cerclage are 1.51 (1.02–2.33) for prior A and 1.11 (0.72–1.77) for prior C. The probability of cerclage benefit ranged from 2.1% for prior A to 31.4% for prior C. By comparison, the conventional risk ratio (95% confidence interval) for early delivery, based on the data alone, is 2.08 (1.18–3.69). Conclusions: As might be anticipated, those with low expectation of cerclage benefit remain more convinced of the ineffectiveness (or harm) of the procedure than those with higher expectations.
A closer look into close packing: pentacoordinated silicon in a high-pressure polymorph of danburite

High-pressure single-crystal X-ray diffraction study of danburite, CaB2Si2O8, has revealed that it is the first compound showing a step-wise transition of Si coordination from tetrahedral to octahedral through trigonal bipyramidal. Along the compression, the Si2O7 groups of danburite first transform into chains of vertice-sharing SiO5 trigonal bipyramids (danburite-II) and later into chains of edge-sharing SiO6 octahedra (danburite-III).
The MMPI-2/MMPI-2-RF Symptom Validity Scale (FBS/FBS-r) is not a measure of ‘litigation response syndrome’: commentary on Nichols and Gass (2015)

Abstract Objectives: To address (1) Whether there is empirical evidence for the contention of Nichols and Gass that the MMPI-2/MMPI-2-RF FBS/FBS-r Symptom Validity Scale is a measure of Litigation Response Syndrome (LRS), representing a credible set of responses and reactions of claimants to the experience of being in litigation, rather than a measure of non-credible symptom report, as the scale is typically used; and (2) to address their stated concerns about the validity of FBS/FBS-r meta-analytic results, and the risk of false positive elevations in persons with bona-fide medical conditions. Method: Review of published literature on the FBS/FBS-r, focusing in particular on associations between scores on this symptom validity test and scores on performance validity tests (PVTs), and FBS/FBS-r score elevations in patients with genuine neurologic, psychiatric and medical problems. Results: (1) several investigations show significant associations between FBS/FBS-r scores and PVTs measuring non-credible performance; (2) litigants who pass PVTs do not produce significant elevations on FBS/FBS-r; (3) non-litigating medical patients (bariatric surgery candidates, persons with sleep disorders, and patients with severe traumatic brain injury) who have multiple physical, emotional and cognitive symptoms do not produce significant elevations on FBS/FBS-r. Two meta-analytic studies show large effect sizes for FBS/FBS-r of similar magnitude. Conclusions: FBS/FBS-r measures non-credible symptom report rather than legitimate experience of litigation stress. Importantly, the absence of significant FBS/FBS-r elevations in litigants who pass PVTs demonstrating credible performance, directly contradicts the contention of Nichols and Gass that the scale measures LRS. These data, meta-analytic publications, and recent test use surveys support the admissibility of FBS/FBS-r under both Daubert and the older Frye criteria.
Pharmacokinetics and pharmacodynamics of lispro-insulin in hemodialysis patients with diabetes mellitus.

OBJECTIVE Lispro-insulin, after subcutaneous injection in patients with normal renal function, is absorbed faster and has a faster onset of action when compared to regular insulin. However, the pharmacokinetics and pharmacodynamics of lispro-insulin in renal failure have not yet been investigated. PATIENTS AND METHODS Eight patients with diabetes mellitus on long-term hemodialysis received an individualized dose of regular insulin or lispro-insulin in a crossover design. Blood glucose and insulin concentrations were measured before and after the subcutaneous insulin injections. RESULTS Plasma insulin concentrations increased faster (time of maximum concentration tmax 20 vs 40 minutes, p = 0.01) and were higher (standardized maximum concentration Cmax/D 13.6 vs 6.1 microU/ml/U, p = 0.01) after lispro-insulin compared to regular insulin. The area under the curve, clearance and parameters of the hypoglycemic action for the 2 insulin products did not differ significantly, but there was a trend to minimum blood glucose level (time of the blood glucose minimum, Gtmin) to occur earlier with lispro-insulin (120 vs 210 minutes, p > 0.05). Differences in elimination half-life and volume of distribution were explained by flip-flop pharmacokinetics in the case of regular insulin. CONCLUSIONS In hemodialysis patients with diabetes mellitus, lispro-insulin is absorbed faster than regular insulin. Differences in the effects of lispro-and regular insulin can be explained by the differences in pharmacokinetics.
DDAVP IN CHILDHOOD NOCTURNAL ENURESIS

ABSTRACT. A double‐blind study of 18 children aged 6–12 years suffering from primary nocturnal enuresis without signs of underlying organic disease is reported. 20 μg of DDAVP (desamino‐d‐arginine vasopressin, Minirin®) was given intranasally at bedtime. The effect was prompt and satisfactory in 8 children and relatively good in another 8 children. No adverse effects were noted. DDAVP is advocated for temporary use in children with nocturnal enuresis needing immediate help.
Arthroscopic Meniscus Allograft Transplantation in Male Professional Soccer Players

Background: Meniscus allograft transplantation (MAT) is an option for symptomatic patients who have undergone subtotal meniscectomy and can potentially result in pain relief and increased function. Hypothesis: Professional soccer players would benefit from arthroscopic MAT in terms of pain, knee function, and return to play at 36-month follow-up. Study Design: Case series; Level of evidence, 4. Methods: Twelve male patients who had undergone MAT (6 medial, 6 lateral) were prospectively evaluated at 12- and 36-month follow-up. The mean age at the time of surgery was 24.5 ± 3.6 years (range, 19-29 years), and the mean time from meniscectomy to surgery was 37 ± 31 months (range, 2-82 months). The transplantation was performed in patients who had undergone subtotal meniscectomy using an arthroscopic bone plug–free technique with a single tibial tunnel plus “all-inside” meniscus sutures. The anterior horn of the transplanted meniscus was sutured to the capsule and to the remnant of the anterior horn of the native meniscus. Seven patients (58%) underwent concurrent procedures. All patients were evaluated at follow-up by the Tegner, Lysholm, International Knee Documentation Committee (IKDC) subjective, IKDC objective, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and visual analog scale (VAS) for pain scores. Information regarding rehabilitation, return to play, and return to official competition was recorded. Results: Eleven of the 12 patients (92%) returned to play soccer. At 36-month follow-up, 9 patients (75%) were still playing as professionals (Tegner score of 10), whereas 2 patients (17%) were playing as semiprofessionals (Tegner score of 9). The mean time from surgery to the end of rehabilitation was 7.5 ± 2 months, whereas the mean time to official competition was 10.5 ± 2.6 months. Patients demonstrated significant improvements on the median Tegner score from 8 (interquartile range, 3-10) to 10 (interquartile range, 9-10) (P = .0391); the mean Lysholm score from 67 ± 14 to 92 ± 10 (P = .0021); the mean IKDC subjective score from 61.8 ± 16.3 to 85.3 ± 9.8 (P = .0026); the mean IKDC objective score from 1 A, 8 B, 1 C, and 2 D to 7 A and 5 B (P = .0077); the mean WOMAC score from 77.1 ± 15.9 to 92.2 ± 9.1 (P = .0242); and the mean VAS score from 61 ± 16 to 29 ± 32 (P = .0029) at 12-month follow-up. There were no significant improvements in these outcomes at 36-month follow-up. One patient developed a knee infection after MAT plus anterior cruciate ligament allograft reconstruction. This complication was successfully treated, but the patient stopped playing soccer (Tegner score of 3 at 36-month follow-up), and this was considered a failure (8%). Conclusion: Arthroscopic MAT in professional soccer players allowed a return to play at the same level (Tegner score of 10) in 75% of the cases at 36-month follow-up.
Enhanced Electrokinetic Removal of Phenanthrene from Clay Soil by Periodic Electric Potential Application

Abstract Electrokinetically enhanced in-situ flushing using surfactants has the potential to remove polycyclic aromatic hydrocarbons (PAHs) from low permeability clay soils; however, previous research has shown that the applied electric potential produces complex physical, chemical, and electrochemical changes within clay soils that affect mass transfer and overall efficiency. This article presents the results of a laboratory investigation conducted to determine the contaminant mass removal by using a periodic voltage application. The periodic voltage effects were evaluated by performing four different bench-scale electrokinetic tests with the voltage gradient applied continuously or periodically, under relatively low voltage (1.0 VDC/cm) and high anode buffering (0.1 M NaOH) as well as high voltage (2.0 VDC/cm) and low anode buffering (0.01 M NaOH) conditions. For all the tests, kaolin soil was used as a representative clay soil and it was spiked with phenanthrene, a representative PAH, with a target concentration of 500 mg/kg. A nonionic polyoxyethylene surfactant, Igepal CA 720, was used as the flushing solution in all the tests. The voltage was applied according to a cycle of five days of continuous application followed by two days of “down time,” when the voltage was not applied. The results of these experiments show that considerable contaminant removal can be achieved by employing a high, 2.0 VDC/cm, voltage gradient along with a periodic mode of voltage application. The increased removal was attributed to increased phenanthrene solubilization and mass transfer due to the reduced flow of the bulk solution during the down time as well as to the pulsed electroosmotic flow that improved flushing action.
Ecological Impact of Grass Carp : A Review of the Available Data

The exotic grass carp ( Ctenopharyngodon idella ) has been used for almost a half a century in the United States as a biological agent to control and manage aquatic plants. This long-lived generalist herbivore consumes large amounts of vegetation and can considerably alter habitat and impact aquatic communities. We conducted a literature review to determine whether previous studies adequately addressed ecological impacts of grass carp and their underlying mechanisms. Our goal was to identify strengths and limitations of ecological assessment in the literature and suggest a trajectory of future research. The review yielded 1,924 citations on grass carp; however, data on ecological interactions were limited, and most research emphasized the biology of grass carp or eradication of aquatic plants rather than ecological mechanisms responsible for ecosystem-wide impacts. Very few studies addressed effects on habitat complexity or community-structuring processes. We provide a comprehensive tabulated overview of feeding preferences and environmental impacts of grass carp. We argue that ecology is paramount to evaluating grass carp impacts and thorough understanding of these impacts is essential for the appropriate management of aquatic communities. Current knowledge is not sufficient to accurately predict long-term effects of grass carp on freshwater ecosystems. We advise a more cautious approach to developing guidelines for grass carp use.
Comparison of plasma α glutathione S‐transferase concentrations during and after low‐flow sevoflurane or isoflurane anaesthesia

Background: We evaluated the effect of low‐flow sevoflurane anaesthesia, in which compound A is generated, and isoflurane anaesthesia, in which compound A is not generated (n=13 in each group), on hepatocellular integrity using α glutathione S‐transferase (GST). α GST is a more sensitive and specific marker of hepatocellular damage than is aminotransferase activity and correlates better with hepatic histology.
THE EFFECT OF GROWTH AND DEVELOPMENT ON THE PHOSPHOLIPIDS OF THE HUMAN BRAIN

Abstract— The phospholipid content and composition of the different regions of the developing human brain were studied. Brains from 25 fetuses and 9 infants, aged 13 weeks gestation to 26 months, were analysed. The concentration of total lipid‐P was highest in the brain stem and lowest in the cerebellum at any age. Compared with the forebrain or brain stem, the cerebellum had a sharp phospholipid growth spurt between 3 months before and 6 months after birth. Before birth, the phospholipid pattern was similar in each part of the brain, with choline phosphoglycerides as the major phospholipid. After birth, the pattern in the brain stem changed further and ethanolamine phosphoglycerides became the dominant phospholipid, while in the other two there was little change. In all parts of the brain the proportion of sphingomyelin increased. The relative proportion of serine and inositol phosphoglycerides remained almost constant throughout the whole period of development. The possible significances of the changes in the phospholipids in neurological development are discussed.
Balancing engagement and detachment in caregiving.

PURPOSE To investigate how caregivers balance engagement with detachment to cope with cumulative demands and losses. DESIGN Qualitative, descriptive. Population, formal and informal caregivers in the United States. A sample of 14 was studied between 1992 and 1994. METHODS Data were collected in open-ended interviews, then were coded and analyzed using grounded-theory methods. Credibility and fittingness were established. RESULTS Caregivers who balance engagement and detachment can affect outcomes without needing to control outcomes. Such caregivers are pragmatic and make conscious choices based on their emotional needs. They set and maintain limits and boundaries and are able to monitor the balancing process while recognizing the importance of practicing self-care. CONCLUSIONS The longer and more intense a caregiver's involvement, the more important it is to learn to balance engagement and detachment. Caregivers may need to learn effective balancing skills.
The spatiotemporal climate variability over Senegal and its relationship to global climate

Climate variability over Senegal (West Africa) and its relationship to global climate are examined for the period 1979–1998. Monthly observed rainfall for 20 stations and monthly CPC merged analysis precipitation (CMAP) over Senegal were averaged for the months of June, July, August, and September in order to generate seasonal rainfall totals for the wet season, as well as climate indices averaged over the study period. The spatial distribution patterns are mapped and analyzed using ArcGIS Spatial Analyst. Rainfall distribution over Senegal is dominated by a N–S gradient.
Wetland and upland use patterns in semi-aquatic snakes: Implications for wetland conservation

Conservation efforts require detailed knowledge of a species' habitat use and movements about the landscape. We radio-tracked sympatric congeners, the Copperbelly Water Snake (Nerodia erythrogaster neglecta) and the Northern Water Snake (Nerodia sipedon sipedon) in northwestern Ohio and southern Michigan, USA, to investigate differences in the use of wetland and upland habitats between species.Nerodia erythrogaster neglecta used twice as many wetlands (4.1±0.4) asN. s. sipedon (2.1±0.3), moved between these wetlands three times more often (9.1±1.9 times) thanN. s. sipedon (2.8±1.0 times), and moved to small wetlands seven times more often (3.6±0.7 times) thanN. s. sipedon (0.5±0.3 times). Nearly 30% ofN. e. neglecta locations were in uplands, sometimes over 100 m from the nearest wetland. Less than 3% ofN. s. sipedon locations were in upland habitats, and all locations were <30 m from wetlands. We simulated the impact of small wetland loss and demonstrated thatN. e. neglecta would need to move longer than normal distances when traveling between wetlands after small wetlands are lost, whileN. s. sipedon would not. The northernmost populations ofN. e. neglecta are listed as federally threatened and state endangered in Ohio, Michigan, and Indiana;N. s. sipedon remains abundant in this region. Historic and current wetland losses in the midwestern United States may have severely impactedN. e. neglecta populations due to this species' high vagility and use of numerous wetlands. Protection and restoration of wetland landscapes are critical for the long-term persistence of many wetland-associated species, species, includingN. e. neglecta.
Ray tracing results for elevation angle spread of departure and its impact on system performance

Elevation spread of departure angles (ESD) is the key parameter characterizing a 3D fast-fading channel model. 3D channel modeling is currently being studied in 3GPP to enable the development of MIMO techniques exploiting both azimuth and elevation dimensions of the channel. In this paper we use ray-tracing techniques to estimate the ESD behavior in Manhattan and Copenhagen city environments and compare it with the 3GPP ESD model. We also investigate the ESD spread within a cluster of rays and show that the ESD within a cluster depends significantly on the distance of the mobile from the base-station. This characterization addresses a gap in the existing literature. Simulation results show that the performance of MIMO techniques such as vertical sectorization depends significantly on the ESD of the underlying environment. This observation also underscores the importance of an accurate ESD model.
MOPP or radiation in addition to ABVD in the treatment of pathologically staged advanced Hodgkin's disease in children: results of the Children's Cancer Group Phase III Trial.

PURPOSE A randomized trial designed to compare mechlorethamine, vincristine, procarbazine, and prednisone (MOPP)/doxorubicin, bleomycin, vinblastine, and daccarbazine (ABVD) (regimen A) with ABVD plus low-dose regional (extended-field) radiation therapy (EF RT) (regimen B) for the treatment of children and adolescents with stages III and IV Hodgkin's disease was conducted by the Children's Cancer Group (CCG-521) from 1986 until 1990. PATIENTS AND METHODS One hundred eleven eligible patients were randomized, 57 to regimen A and 54 to regimen B. All patients had pathologically verified stage III or stage IV Hodgkin's disease. RESULTS Overall survival (S) is 87% at 4 years and event-free survival (EFS) is 82%. Patients randomized to ABVD plus EF RT have a 4-year EFS of 87% compared with 77% for patients randomized to MOPP/ABVD (P = .09, two-sided). Patients randomized to ABVD plus EF RT have a 4-year S of 90% compared with 84% for patients randomized to MOPP/ABVD (P = .45, two-sided). Significant prognostic factors in multivariate analysis for EFS are stage of disease, erythrocyte sedimentation rate (ESR) at diagnosis, liver size at diagnosis, and, among stage III patients, the size of the mediastinal mass at diagnosis. The acute toxicities of treatment are largely hematopoietic in nature, whereas acute pulmonary and cardiac toxicities are modest and not limiting. CONCLUSION The results of this study show that, in advanced-stage Hodgkin's disease in children, equivalent results can be obtained by the addition of either MOPP or low-dose EF RT to the ABVD regimen; whether the addition of either contributes to outcome was not addressed in this study and will require additional testing. It is clear, however, that MOPP chemotherapy can safely be eliminated from front-line combination chemotherapy regimens for advanced Hodgkin's disease in pediatric patients.