Miracle-dz/UniFAR-FTUs huggingface dataset:
Atrial fibrillation detected initially during acute medical illness: A systematic review

Objective: There is uncertainty about the incidence of and prognosis associated with atrial fibrillation that is documented for the first time in the setting of an acute stressor, such as surgery or medical illness. Our objective was to perform a systematic review of the incidence and long-term recurrence rates for atrial fibrillation occurring transiently with stress in the setting of acute medical illness. Data sources: Medline, Embase and Cochrane Central to September 2017. Study selection: We included retrospective and prospective observational studies, and randomised controlled trials. The population of interest included patients hospitalised for medical (i.e. non-surgical) illness who developed newly diagnosed atrial fibrillation. Studies were included if they included data on either the incidence of atrial fibrillation or the rate of atrial fibrillation recurrence in atrial fibrillation occurring transiently with stress patients following hospital discharge. Data extraction: Two reviewers collected data independently and in duplicate. We characterised each study’s methodology for ascertainment of prior atrial fibrillation history, atrial fibrillation during hospitalisation and atrial fibrillation recurrence after hospital discharge. Data synthesis: Thirty-six studies reported the incidence of atrial fibrillation. Ten used a prospective design and included a period of continuous electrocardiographic (ECG) monitoring. Atrial fibrillation incidence ranged from 1% to 44%, which was too heterogeneous to justify meta-analysis (I2=99%). In post-hoc meta-regression models, the use of continuous ECG monitoring explained 13% of the variance in atrial fibrillation incidence, while care in an intensive care unit explained none. Two studies reported the long-term rate of atrial fibrillation recurrence following atrial fibrillation occurring transiently with stress. Neither of these studies used prospective, systematic monitoring. Recurrence rates at 5 years ranged from 42% to 68%. Conclusions: The incidence of atrial fibrillation with medical illness may be as high as 44%, with higher estimates in reports using continuous ECG monitoring. Within 5 years following hospital discharge, atrial fibrillation recurrence is documented in approximately half of patients; however, the true rate may be higher. Protocol registration PROSPERO CRD42016043240
Circulating Tumor Cells with Stemness and Epithelial-to-Mesenchymal Transition Features Are Chemoresistant and Predictive of Poor Outcome in Metastatic Breast Cancer

Circulating tumor cells (CTCs) bearing phenotypes related to cancer stem cells (CSCs) and epithelial-to-mesenchymal transition (EMT) have been identified in breast cancer; however, their clinical significance is not clear. In the current study, we investigated the prognostic relevance of single CSC+/partial-EMT+ CTCs in patients with metastatic breast cancer and the effect of first-line chemotherapy on their incidence. For this purpose, triple immunofluorescence against cytokeratin, ALDH1, and TWIST1 was performed in peripheral blood mononuclear cell (PBMC) cytospins from 130 patients before and after first-line chemotherapy. CSC+/partial-EMT+ CTCs were characterized as cells co-expressing cytokeratin, high levels of ALDH1, and nuclear TWIST1. CSC+/partial-EMT+ CTCs were evident in 27.7% of patients at baseline and were correlated to lung metastases (P = 0.010) and decreased progression-free survival [PFS; median 10.2 (8.9–11.6) vs. 13.5 (11.3–15.7) months; P = 0.024]. Their detection was an independent factor predicting for increased risk of relapse [multivariate analysis; HR (95% confidence interval (CI)): 1.785 (1.171–2.720); P = 0.007]. In HER-2–negative patients, CSC+/partial-EMT+ CTCs were additionally associated with reduced overall survival (OS) [median 39 (26.2–51.9) vs. 51 (15.7–86.4) months; P = 0.020] and increased risk of death [multivariate analysis; HR (95% CI): 2.228 (1.066–4.655); P = 0.033]. Chemotherapy resulted in a significant increase in the incidence of CSC+/partial-EMT+ CTCs (mean CTC% per patient: 59.4% post vs. 39.5% pre; P = 0.018), which was subsequently confirmed only in HER2-negative patients (P = 0.040) and in non-responders at the end of treatment (P = 0.020). In conclusion, CSC+/partial-EMT+ CTCs represent a chemoresistant subpopulation, which independently predicts for unfavorable outcome in metastatic breast cancer. Efficient targeting of these CTCs could potentially increase patient survival.
An Epidemiological Analysis of Head Injuries in Taiwan

Traumatic head injuries occur frequently in Taiwan, having catastrophic consequences for the victims, their families, and society as a whole. However, little is known about the risk factors at the population level in Taiwan. The primary aim of this study was to obtain more information on these variables and their relationships. Another aim was to analyze the effects of independent variables such as sex, age, residency, pre-existing conditions, mechanisms of injury, associated injuries, and severity on the probability of in-hospital death. Using the 2007–2008 total admissions claim dataset from Taiwan’s National Health Insurance system, total admissions due to acute head injury were selected for further analysis. The obtained data included patient demographics and trauma hospitalization rate. A total of 99,391 patients were admitted with head injury, 48,792 of which had moderate-to-severe head injury. There were 4935 cases recorded as in-hospital mortality and the standardized in-hospital mortality rate was 10.7 deaths per 100,000 person-years. The mortality rate increased with age. After adjustments, male sex, age older than 54 years, living in a rural area, lower monthly income, a Charlson comorbidity index greater than one, being a pedestrian hit by a motor vehicle, fall from a height, and having significant chest, abdominal, or lower extremity injury increased the risk of death during admission. This population-based analysis provides information about the incidence rate and death rate for admissions in Taiwan due to acute head injury and the factors that affect in-hospital mortality. Our results that highlight the risk factors for adverse outcome can help us prevent or improve rural area trauma care of head injury patients in the future.
Culture Difference and the Impact on Online Review Helpfulness: From the Analytic and Holistic Cognitive Processing Perspective

Consumers with different national culture backgrounds heavily depend upon product review to make the shopping decisions, and thus product review helpfulness significantly influences the business performance in the e-commerce context. However, prior literature neglected the heterogeneity of different national cultures, which could cause a shift in consumers’ perception towards the review helpfulness. To fill the research gap, this paper builds upon a cultural induced cognitive processing theoretical framework, the Nisbett’s analytic and holistic cognitive processing style framework, and proposes that consumers from East Asian countries and Western countries possess different cognitive processing style, thus relying on different product review features to assess product review helpfulness. Our conception is supported by an analytical investigation of a unique dataset from a major B2C shopping website in Western countries and its similar twin website in East Asian countries. Implications for researchers and practitioners are provided at the end of this paper.
Spatial Algal Bloom Characterization by Landsat 8-Oli and Field Data Analysis

Water pollution is an important problem around the world as it is closely related to human and environmental health. Field campaigns are expensive, time consuming and may provide little information. Remote sensing provides synoptic spatio-temporal views and can lead to a better understanding of lake ecology. In this work an extreme algal bloom event which occurred in a reservoir is characterized by LANDSAT8-OLI sensor and in situ sampling. Chlorophyll-a concentration and algae abundance data are measured on samples collected simultaneously with satellite pass and used to build semiempirical models. Two linear functions to calculate chlorophyll-a from satellite data are presented and compared. A linear model from band 2 (blue) and band 5 (NIR) presents the best performance with a determination coefficient equal to 0,89. In situ and satellite chlorophyll-a lead comparable trophic class assessment, hypertrophic. Both Models fail to predict chlorophyll-a concentration near river intrusion (North), where low values of reflectance are recorded.
"Run Forrest Run!": Measuring the Impact of App-Enabled Performance and Social Feedback on Running Performance

Exercise tracking apps offer a novel and powerful channel to deliver behavioral interventions at a massive scale. As thousands of fitness tracking solutions emerge, the lack of systematic research quantifying their effectiveness on exercise outcomes becomes more prominent. Drawing on the motivation literature, this paper elucidates the effects of app-enabled motivation on fitness improvement. Specifically, this study examines the two most common forms of feedback available to users of exercise tracking apps, namely performance feedback and social feedback. The results of our field experiment reveal strong evidence that performance feedback and social feedback motivate fitness improvement. Furthermore, whereas the effect of social feedback diminishes over time, the effect of performance feedback remains resilient. There theoretical and practical implications of the findings are discussed.
Naltrexone differentially modulates the neural correlates of motor impulse control in abstinent alcohol‐dependent and polysubstance‐dependent individuals

Identifying key neural substrates in addiction disorders for targeted drug development remains a major challenge for clinical neuroscience. One emerging target is the opioid system, where substance‐dependent populations demonstrate prefrontal opioid dysregulation that predicts impulsivity and relapse. This may suggest that disturbances to the prefrontal opioid system could confer a risk for relapse in addiction due to weakened ‘top‐down’ control over impulsive behaviour. Naltrexone is currently licensed for alcohol dependence and is also used clinically for impulse control disorders. Using a go/no‐go (GNG) task, we examined the effects of acute naltrexone on the neural correlates of successful motor impulse control in abstinent alcoholics (AUD), abstinent polysubstance‐dependent (poly‐SUD) individuals and controls during a randomised double blind placebo controlled fMRI study. In the absence of any differences on GNG task performance, the AUD group showed a significantly greater BOLD response compared to the control group in lateral and medial prefrontal regions during both placebo and naltrexone treatments; effects that were positively correlated with alcohol abstinence. There was also a dissociation in the positive modulating effects of naltrexone in the orbitofrontal cortex (OFC) and anterior insula cortex (AIC) of the AUD and poly‐SUD groups respectively. Self‐reported trait impulsivity in the poly‐SUD group also predicted the effect of naltrexone in the AIC. These results suggest that acute naltrexone differentially amplifies neural responses within two distinct regions of a salience network during successful motor impulse control in abstinent AUD and poly‐SUD groups, which are predicted by trait impulsivity in the poly‐SUD group.
From reading books to increased smart device screen time

The number of people with myopia is expected to rise from 1.950 billion in 2010 to 4.758 billion by 2050.1 In Asia, the prevalence of myopia in teenagers has been reported to be as high as 96.5%. 2 One study demonstrated that 11% of Singaporean preschoolers were already myopic, placing them at a significantly higher risk of developing high myopia and myopic macular degeneration.3 This myopia ‘epidemic’ has become a profound public health concern. In Singapore, the direct cost of managing myopia was estimated at US$755 million annually, and globally at US$328 billion per year.4 It is now thought that because of the rapid increase in the prevalence of myopia in under one generation, environmental factors perhaps play a greater role in its development than our genes. Environmental risk factors include urbanisation, higher educational attainment, higher IQ, but more important has been two consistent risk factors: increased near-work activity and reduced outdoor activity.5 Studies often quantify near-work activity by the number of books …
Continuous Infusion versus Intermittent Dosing with Pantoprazole for Gastric Endoscopic Submucosal Dissection

Background/Aims Proton pump inhibitors are widely used to prevent gastric endoscopic submucosal dissection (ESD)-related bleeding, but no standard administration regimens have been established. We aimed to prospectively compare the effects of continuous infusion and intermittent dosing with pantoprazole on preventing gastric ESD-related bleeding. Additionally, we analyzed the risk factors for bleeding. Methods From April 2012 to May 2013, patients with a gastric epithelial neoplasm scheduled for ESD in the Pusan National University Hospital were randomly assigned to one of two groups according to the pantoprazole administration regimen (continuous infusion or intermittent dosing). The primary outcomes measured were intra- and postprocedural bleeding events. Results The final analysis included 401 patients. The rate of significant intraprocedural bleeding was 25.4% in the C group and 24.0% in the I group, with no significant difference (p=0.419). In addition, there was no significant difference in the postprocedural bleeding rate between the C and I groups (11.7% vs 10.2%, p=0.374). Multivariate analysis showed that intraprocedural bleeding was associated with the proximal tumor location, the presence of fibrosis, and the size of the resected specimen, whereas postprocedural bleeding was associated with the size of the resected specimen and the procedure/coagulation time. Conclusions Intermittent dosing with pantoprazole is sufficient and cost-effective for the prevention of gastric ESD-related bleeding. Operators should consider tumor characteristics when planning ESD to minimize the risk of intraprocedural bleeding, and patients with large iatrogenic ulcers should be carefully monitored for postprocedural bleeding.
Improving Spatial Resolution and Test Times of Visual Field Testing Using ARREST

Purpose Correctly classifying progression in moderate to advanced glaucoma is difficult. Pointwise visual field test–retest variability is high for sensitivities below approximately 20 dB; hence, reliably detecting progression requires many test repeats. We developed a testing approach that does not attempt to threshold accurately in areas with high variability, but instead expends presentations increasing spatial fidelity. Methods Our visual field procedure Australian Reduced Range Extended Spatial Test (ARREST; a variant of the Bayesian procedure Zippy Estimation by Sequential Testing [ZEST]) applies the following approach: once a location has an estimated sensitivity of <17 dB (a “defect”), it is checked that it is not an absolute defect (<0 dB, “blind”). Saved presentations are used to test extra locations that are located near the defect. Visual field deterioration events are either: (1) decreasing in the range of 40 to 17 dB, (2) decreasing from >17 dB to “defect”, or (3) “defect” to blind. To test this approach we used an empirical database of progressing moderate-advanced 24-2 visual fields (121 eyes) that we “reverse engineered” to create visual field series that progressed from normal to the end observed field. ARREST and ZEST were run on these fields with test accuracy, presentation time, and ability to detect progression compared. Results With specificity for detecting progression matched at 95%, ZEST and ARREST showed similar sensitivity for detecting progression. However, ARREST used approximately 25% to 40% fewer test presentations to achieve this result in advanced visual field damage. ARREST spatially defined the visual field deficit with greater precision than ZEST due to the addition of non–24-2 locations. Conclusions Spending time trying to accurately measure visual field locations that have high variability is not productive. Our simulations indicate that giving up attempting to quantify size III white-on-white sensitivities below 17 dB and using the presentations saved to test extra locations should better describe progression in moderate-to-advanced glaucoma in shorter time. Translational Relevance ARREST is a new visual field test algorithm that provides better spatial definition of visual field defects in faster test time than current procedures. This outcome is achieved by substituting inaccurate quantification of sensitivities <17 dB with new spatial locations.
Towards an Improved Inventory of N2O Emissions Using Land Cover Maps Derived from Optical Remote Sensing Images

The Intergovernmental Panel on Climate Change (IPCC) Tier 1 approach is applied to estimate emissions of N2O over an agricultural landscape located in southwestern of France. Yearly maps of potential N2O emissions are derived at a territory scale from land cover classifications, theoretical amount of mineral nitrogen (N) applied and an emission factor. The methodology takes advantage of the regular high resolution optical remote sensing images acquired during the 2006–2016 period to provide land cover maps with an overall accuracy superior to 0.87. Over the study area, the first yearly total N2O emissions estimations range from 105 to 113 tons for the 2014–2016 period. Future works will allow analyzing the estimates of potential N2O emissions and the potential associated error sources over the entire last decade.
Investigation of Optimal Afferent Feedback Modality for Inducing Neural Plasticity with A Self-Paced Brain-Computer Interface

Brain-computer interfaces (BCIs) can be used to induce neural plasticity in the human nervous system by pairing motor cortical activity with relevant afferent feedback, which can be used in neurorehabilitation. The aim of this study was to identify the optimal type or combination of afferent feedback modalities to increase cortical excitability in a BCI training intervention. In three experimental sessions, 12 healthy participants imagined a dorsiflexion that was decoded by a BCI which activated relevant afferent feedback: (1) electrical nerve stimulation (ES) (peroneal nerve—innervating tibialis anterior), (2) passive movement (PM) of the ankle joint, or (3) combined electrical stimulation and passive movement (Comb). The cortical excitability was assessed with transcranial magnetic stimulation determining motor evoked potentials (MEPs) in tibialis anterior before, immediately after and 30 min after the BCI training. Linear mixed regression models were used to assess the changes in MEPs. The three interventions led to a significant (p < 0.05) increase in MEP amplitudes immediately and 30 min after the training. The effect sizes of Comb paradigm were larger than ES and PM, although, these differences were not statistically significant (p > 0.05). These results indicate that the timing of movement imagery and afferent feedback is the main determinant of induced cortical plasticity whereas the specific type of feedback has a moderate impact. These findings can be important for the translation of such a BCI protocol to the clinical practice where by combining the BCI with the already available equipment cortical plasticity can be effectively induced. The findings in the current study need to be validated in stroke populations.
High-Speed Railway Bridge Vibration Measurement and Analysis Based on Radar Interferometry

A newly designed radar based on interferometry is proposed and well designed in the paper. The designed radar can detect the vibration of the railway bridge with a super-resolution and a high precision, which also has remote sensing ability. The general bridge monitoring methods are expensive and time-consuming since it is difficult to install sensors that should be directly contact with the bridge, such as accelerometer and dynamometer. Based on the designed radar, experiments are constructed on a Beijing-Tianjin Inter-City high-speed railway bridge to prove that the radar interferometry can be used to preciously and accurately monitor the railway bridge's vibration.
Surface Soil Moisture Estimation from Modis Apparent Thermal Inertia: A Comparison With Smos And Smap Soil Moisture Products

L-band radiometry has been considered the preferred technique for global soil moisture (SM) remote sensing, as the Soil Moisture and Ocean Salinity (SMOS) and the Soil Moisture Active Passive (SMAP) missions proved. Owing the limited spatial resolution of current L-band radiometers, several downscaling algorithms have been developed to enhance the SMOS and SMAP SM resolutions. In this regard, the apparent thermal inertia (ATI) may be used for indirectly estimating SM, not only for disaggregation. In this study, l-km ATI-derived SM was obtained from March 31, 2015 to December 31, 2016, using Moderate Resolution Imaging Spectroradiometer (MODIS) as an alternative to L-band radiometry. The ATI-derived SM was validated over the Soil Moisture Measurement Stations Network of the University of Salamanca (REMEDHUS). Comparisons with in situ SM showed slightly lower correlation (~0.62), but similar error (~0.043 m3·m−3) and lower bias (~0.027 m3·m−3) than the existing SMOS and SMAP products, whilst improving the resolution.
Hardware Distortion Correlation Has Negligible Impact on UL Massive MIMO Spectral Efficiency

This paper analyzes how the distortion created by hardware impairments in a multiple-antenna base station affects the uplink spectral efficiency (SE), with a focus on massive multiple input multiple output (MIMO). This distortion is correlated across the antennas but has been often approximated as uncorrelated to facilitate (tractable) SE analysis. To determine when this approximation is accurate, basic properties of distortion correlation are first uncovered. Then, we separately analyze the distortion correlation caused by third-order non-linearities and by quantization. Finally, we study the SE numerically and show that the distortion correlation can be safely neglected in massive MIMO when there are sufficiently many users. Under independent identically distributed Rayleigh fading and equal signal-to-noise ratios (SNRs), this occurs for more than five transmitting users. Other channel models and SNR variations have only minor impact on the accuracy. We also demonstrate the importance of taking the distortion characteristics into account in the receive combining.
Using Virtual Reality for Museum Exhibitions: The Effects of Attention and Engagement for National Palace Museum

Information technologies provide important opportunities for museums to create more engaging visitor experience. This study collaborates with National Palace Museum and focuses on investigating whether virtual reality is an effective communication medium for museum exhibition. We compare three communication mediums--video, website and virtual reality and investigate their impacts on user experience, in terms of engagement and attention. We are also interested in the role of users’ personality and their prior experience of communication media in moderating these effects. The results of findings show that virtual reality can catch more attention from user, and attention enforces their engagement, which leads to better user experience. Furthermore, personality and relative experience are both insignificant in mediating the relationship between engagement and visit intention, but we found that when using communication medium, extravert can have higher attention than the other users, which deserve more study in the future.