Miracle-dz/UniFAR-FTUs huggingface dataset:
Valuation of sequential R&D investment under technological, market, and rival preemption uncertainty

We develop a real options model for evaluating and optimizing an R&D project. The model can capture key features of R&D, including research duration, growth opportunity, debt financing, and uncertainty of technological, demand market, and rival preemption. Nevertheless, it is computationally tractable and thus helps practitioners to evaluate various cases of R&D investment. Further, by analyzing the model with a wide range of parameter values, we unveil the interactions of key R&D features. The effect of duration on investment depends on whether there is a possibility of rival preemption. Higher uncertainty of research duration speeds up project inception in the presence of rival preemption. Higher uncertainty of technological success, combined with a growth opportunity embedded in the R&D project, accelerates investment. Debt financing can greatly decrease time lag between the first stage project and growth project. These results are consistent with the empirical evidence.
Performance of prototypes and start up of series fabrication of the LHC arc quadrupoles

The construction of three prototype arc quadrupoles for the LHC machine has been concluded successfully. These magnets underwent warm and cold magnetic measurements as well as many other tests, both in CEA-Saclay's laboratory and at CERN. Their training qualifies them for use in the LHC machine and their measured field quality points to only very minor corrections. An excellent correlation is found between warm and cold magnetic measurements. The prototype quadrupole design has been fully retained for the series fabrication of the 400 magnets and their cold masses by industry. This paper describes the main tests and measurement results of all three prototypes. It further explains the logistics for the manufacturing of the series of cold masses. These cold masses contain not only the main quadrupole but also different combinations of corrector magnets. Thus, together with variants imposed by the cryogenic configuration of the machine, 40 different types of cold masses have to be fabricated by the firm, to which the contract has been adjudicated.
Protein‐Mediated Synthesis of Uniform Superparamagnetic Magnetite Nanocrystals

Magnetite nanocrystals are synthesized in the presence of a recombinant Mms6 protein thought to be involved in the biomineralization of bacterial magnetite magnetosomes, the mammalian iron‐storage protein, ferritin, and two proteins not known to bind iron, lipocalin (Lcn2) and bovine serum albumin (BSA). To mimic the conditions at which magnetite nanocrystals are formed in magnetotactic bacteria, magnetite synthesis is performed in a polymeric gel to slow down the diffusion rates of the reagents. Recombinant Mms6 facilitates formation of ca. 30 nm single‐domain, uniform magnetite nanocrystals in solution, as verified by using transmission electron microscopy analysis and magnetization measurements. The nanocrystals formed in the presence of ferritin, Lcn2, and BSA, do not exhibit the uniform sizes and shapes observed for those produced in the presence of Mms6. Mms6‐derived magnetite nanoparticles show the largest magnetization values above the blocking temperature, as well as the largest magnetic susceptibility compared to those of the nanomaterials synthesized with other proteins. The latter is indicative of a substantial effective magnetic moment per particle, which is consistent with the presence of magnetite with a well‐defined crystalline structure. The combination of electron microscopy analysis and magnetic measurements confirms our hypothesis that Mms6 promotes the shape‐selective formation of uniform superparamagnetic nanocrystals. This provides a unique bioinspired route for synthesis of uniform magnetite nanocrystals.
Integrated prediction model of iron concentration in goethite method to remove iron process

To deal with the problem of detecting the concentration of Fe2+ and Fe3+ in the goethite method to remove iron process of a smelting production enterprises,on the basis of Outokumpu production equipment and technology,by using improved least squares support vector machine to realize the nonlinear prediction for small sample and process neural networks to realize the time cumulative effect of historical data series,an integrated prediction model is proposed based on information entropy method.Simulation results show that,the integrated prediction model has good prediction performance which satisfies the error request of the iron concentration in goethite method to remove iron process.
Network RTK: Same look and feel... only better

Easier, more accurate and more reliable Global Navigation Satellite System (GNSS) positioning is increasingly becoming available to Continuously Operating Reference Station (CORS) users in Australia. Generally at no extra effort or cost to the user, thanks to the growing availability of Network Real Time Kinematic (NRTK). Until recently, NRTK services were only available in major urban areas but are now rapidly becoming accessible in regional areas. This transition to the next level of GNSS positioning is made possible by many factors, including GNSS modernisation and the rapid densification of nationwide CORS infrastructure. Many professionals currently enjoy the high precision and increased productivity offered by single-base RTK systems. For the user in the field, NRTK has the same ‘look and feel’ as traditional RTK. only it’s better. In this article we quickly review the core difference between conventional, single-base RTK and NRTK. Using CORSnet-NSW, 5 million observations and 1750 station occupations in several test areas across NSW, we then show that NRTK consistently outperforms single-base RTK in both precision and accuracy.
Histological and Ultrastructural studies on the kidneys of albino rat under the effect of tiaprofenic acid and the possibility of recovery after stoppage of the drug

ABSTRAT The present study was performed to evaluated the pathological effect s of tiaprofenic acid (surgam) on the kidneys of adult male albino rat and the possibility of recovery after stoppage of the drug administration. 40 male albino rats divided into 4 equal groups were used in this study. Group I: (the control group) the animals were intramuscularly injected with 0.5 ml physiological saline solution. Group II, the animals were intramuscularly injected with the therapeutic dose of tiaprofenic acid (TA) (18 mg/kg b.w.) every 12 hours for 2 weeks. Group III, the animals were intramuscularly injected with double the therapeutic dose of (TA) (36 mg/kg b.w.) every 12 hours for 2 weeks. Group IV, the animals were intramuscularly injected with double the therapeutic dose of (TA) (36 mg/kg b.w.) every 12 hours for 2 weeks and then left without trea tment for 4 weeks for the possibility of recovery. Animals of groups I,II,III were sacrificed 24 hours after the last dose, while animals of group IV were sacrificed 4 weeks after the last dose, and the kidney samples were obtained and processed for histological and ultrastructural examination s. Histological changes in the rat kidney induced by tiaprofenic acid (TA) included hypertrophied glomeruli, swelling of the parietal epithelial cells, proliferation of the mesangial cells, and narrowing of the urinary spaces. Moreover, the cells of the proximal and distal convoluted tubules showed marked cloudy swelling with hypertrophied nuclei ; some displayed signs of pyknosis and karyolysis. Many infla mmatory cells invading the intertubular spaces were also seen.Ultrastructural observations revealed sw ollen of the parietal epithelial cells of Bo wman’s capsules , narrow urinary spaces, focal fusion of the visceral epithelial cells, thickened glomerular basement membrane and dilated glomerular capillaries with the prescence of amorphous materials as well as blood cells in the capillaries lumina. The proximal convoluted tubules showed erosion of the microvilli constituting the brush borders, with cell debris or cast in the lumina of the tubules; besides, degenerated mitochondria and lysosomes, fragmented rough endoplasmic reticulum and destruction of the basal infolding s were observed. The epithelial cells of the distal convoluted tubules manifested marked loss of some basal infoldings as well as degenerated mitochondria, and destructed endoplasmic reticulum. However, in the recovery group there was marked improvment in the kidney tissues which appeared more or less normal.
Reversals of preference between bids and choices in gambling decisions.

Abstract : Subjects in 3 experiments chose their preferred bet from pairs of bets, and later bid for each bet separately. In each pair, one bet had a higher probability of winning (P bet); the other offered more to win (S bet). Bidding method (selling vs. buying) and payoff method (real-play vs. hourly wage) were varied. Results showed that when the P bet was chosen, the $ bet often received a higher bid. These inconsistencies are incompatible with risky decision models, but can be understood via information-processing considerations. (Author)
Perceptions of hybrid concrete construction in the UK construction industry

The findings from a survey of attitudes amongst professional and trade (PT) groups in the UK construction industry in relation to the use of hybrid concrete construction (HCC) are reported in this paper. Following a brief introduction to HCC, the context of the research presented here is explained. An account of the research methods used in the project is given, together with guidance on appropriate techniques for interviewing professional and trade groups in the construction industry. The findings from the survey are divided into two sections: areas of consensus and areas of disagreement. Conclusions are drawn relating to the future design, procurement and construction of buildings that incorporate HCC.
Forecasting northern polar stratospheric variability using a hierarchy of statistical models

The northern polar stratosphere plays an important role in modulating the wintertime near-surface temperature conditions in midlatitudes. Forecasting northern polar stratospheric variability will have the potential to extend the winter weather forecasts in midlatitudes. As such, this research seeks to explore a novel approach of forecasting short-term northern polar stratospheric variability using a hierarchy of linear and non-linear statistical models. In addition to El Nino Southern Oscillation, the Quasi-biennial Oscillation, and the 11-year solar cycle indices, this research uses the upward flux of wave activity from the troposphere into the stratosphere as a predictor for modeling and forecasting northern polar stratospheric temperature and geopotential height anomalies. The upward flux of wave activity entering the stratosphere is the primary source of intraseasonal variability in the wintertime stratospheric polar vortex. Multiple linear regression and machine learning models were trained over the 1980-2005 time period, and the 10-day and 20-day northern polar stratospheric temperature and geopotential height forecasts were generated over the 2005-2011 time period. The importance of each predictor for modeling northern polar stratospheric variability was assessed using a permutation-based method. The study has found that the use of the meridional wave heat flux predictors improves the accuracy of short-term northern polar stratospheric geopotential height forecasts as demonstrated by the correlation coefficient of 0.48 over the 2005-2011 time period. In contrast to previous studies, multiple linear regression shows better predictive performance than the machine learning models over the 2005-2011 time period. A better predictive performance of multiple linear regression in comparison to machine learning models is due to a much higher contribution of the upward flux of wave activity than other predictors to forecast skill.
Ayvalik ve Memecik Zeytin Çeşitlerinin Yapraği ve Meyvelerinin Toplam Fenolik Madde Miktarı ve Antioksidan Aktiviteleri

Bu calismada 2008/09 ve 2009/10 hasat yillarinda Bornova Zeytincilik Arastirma Istasyonu Mudurlugu bahcesinden toplanan Ayvalik ve Memecik zeytin yapragi ve zeytin meyvelerinin toplam fenolik madde miktari, DPPH• ve ABTS•+ radikal supurucu aktiviteleri incelenmistir. Istatistiksel olarak cesitlere gore zeytin yapraginin DPPH• ve ABTS•+ radikal supurucu aktiviteleri, zeytin meyvesinin toplam fenolik madde miktari, DPPH• ve ABTS•+ radikal supurucu aktiviteleri onemli bulunmustur (P<0.001). Ayvalik zeytin yapraginin toplam fenolik madde miktarlarinin 2008/09 ve 2009/10 yillarinda sirasi ile 237.73 ve 235.64 mgCAE/100 g, Memecik zeytin yapraginin 230.64 ve 233.73 mgCAE/100 g, Ayvalik zeytin meyvesinin 279.39 ve 198.87 mgCAE/100 g ve Memecik zeytin meyvesinin 349.72 ve 253.40 mgCAE/100 g oldugu saptanmistir. Sonuc olarak her iki hasat yilinda da toplam fenolik madde miktarlari acisindan Ayvalik ve Memecik zeytin cesitlerinin yapraklari arasinda onemli bir fark olmadigi, fakat Memecik zeytin meyvesinin toplam fenolik madde miktarinin Ayvalik zeytin meyvesine gore daha yuksek oldugu tespit edilmistir.
Participatory Theater, Is It Really? A Critical Examination of Practices in Timor-Leste

Dance, music, and oral narratives are an important and vibrant part of cultural practice and heritage in Timor-Leste. But while Timorese people have used such creative methods and processes during rituals, celebrations, and their fi ght for independence, today arts and artistic expression become an increasingly popular strategy in development cooperation. Especially diff erent forms of so-called participatory theater with origins in development cooperation, arts, and social movements, present themselves as innovative, participatory, and well applicable in terms of capacity building and stimulating positive social transformation. Based on the author’s experience and observations, this article critically examines the alliance between various stakeholders in Timor-Leste engaging with the fact that the current scene of participatory theater can hardly be seen as an independent grassroots or even social movement, rather than an initiated top-down process by donors with specifi c agendas.
Improving the representation of anthropogenic CO2 emissions in climate models: impact of a new parameterization for the Community Earth System Model (CESM)

Abstract. ESMs (Earth system models) are important tools that help scientists understand the complexities of the Earth's climate. Advances in computing power have permitted the development of increasingly complex ESMs and the introduction of better, more accurate parameterizations of processes that are too complex to be described in detail. One of the least well-controlled parameterizations involves human activities and their direct impact at local and regional scales. In order to improve the direct representation of human activities and climate, we have developed a simple, scalable approach that we have named the POPEM module (POpulation Parameterization for Earth Models). This module computes monthly fossil fuel emissions at grid-point scale using the modeled population projections. This paper shows how integrating POPEM parameterization into the CESM (Community Earth System Model) enhances the realism of global climate modeling, improving this beyond simpler approaches. The results show that it is indeed advantageous to model CO2 emissions and pollutants directly at model grid points rather than using the same mean value globally. A major bonus of this approach is the increased capacity to understand the potential effects of localized pollutant emissions on long-term global climate statistics, thus assisting adaptation and mitigation policies.
Context-Specific Dimensions of Trust in Manager, Subordinate and Co-Worker in Organizations

The purpose of this study is to determine the dimensions of trust relationship among managers, subordinates and the co-workers in organizations. Using an original trust questionnaire data has been collected from 550 middle-level managers from organizations operating in different regions of Turkey. Results from both qualitative and quantitative research methods indicate that the dimensions of trust vary in organizational relationships between managers and subordinates and between co-workers and furthermore, that a culture-specific meaning is attributed to its content. This study contributes to trust literature developing three original sub-scales and also it indicates that the meaning of trust in organizational relationships is influenced by cultural context.
Kobe University Repository : Kernel タイトル Tit le Neural and Genet ic Correlates of the Social Sharing of Happiness 著者

権利 Rights This Document is Protected by copyright and was first published by Front iers. All rights reserved. It is reproduced with permission. © 2017 Matsunaga, Kawamichi, Umemura, Hori, Shibata, Kobayashi, Suzuki, Ishii, Ohtsubo, Noguchi, Ochi, Yamasue and Ohira. This is an openaccess art icle distributed under the terms of the Creat ive Commons Attribut ion License (CC BY). The use, distribut ion or reproduct ion in other forums is permit ted, provided the original author(s) or licensor are credited and that the original publicat ion in this journal is cited, in accordance with accepted academic pract ice. No use, distribut ion or reproduct ion is permit ted which does not comply with these terms.
Protein patterns of Admiral- treated and untreated house dust mites: Dermatophagoides pteronyssinus and Dermatophagoides farinae (Acarina: Pyroglyphidae)

The present work deals with the study of the effect of Admiral "pyriproxyfen” as a juvenile hormone analogue (JHA) on the protein patterns of the two common house dust mites (HDM): Dermatophagoides pteronyssinus and D. farinae. Analysis revealed lower protein content in either JHA-treated or untreated tritonymphs than in the respective adults. JHA treatment affected protein concentration of both tritonymphs (significantly increased) and adults (significantly decreased). Significantly lower protein contents were detected for D. farinae than for D. pteronyssinus either in normal or JHA-treated individuals. A total of 49 bands with molecular weights of 10-108 Kilo Daltons (KD) and relative mobilities of 0.990. 16 were electrophoretically separated from the whole body tissue extracts of normal and treated tritonymphs and adults of the two species. Four common bands (12-60 KD) were suggested as genus-specific. Three D. pteronyssinus proteins (21-33 KD) and one D. farinae protein (69 KD) were suggested as speciesspecific. The HDM allergen (14-15 KD) was detected in the two mite species. Several proteins that detected in normal individuals of the two species disappeared in the respective treated individuals that may be due to the effect of treatment with such JHA.
An Experimental Study on the Mechanical Behavior of a Depth Hoar Layer Under Shear Stress (Preliminary Report)

Simple shear experiments were carried out to understand the mechanical behavior of a depth hoar layer at various shear strain rates of 10-5 S-l to 10-3 S-l at temperature of -6 °C. Ductile deformation took place in the layer at the shear strain rate lower than 8 x 10-5 s-l and typical brittle fracture took place at the shear strain rate higher than 2 x 10-4 S-l. The critical shear strain rate for the ductile-brIttle transition was considered to be between these values. Shear strength increased with increasing shear strain rate within the ductile deformation region and took tile peak value at the critical shear strain rate for the ductile-brittle tranSItion. Experimental result indicated that a natural slab avalanche does not occur in the absence of super-weak zone in the weak layer dealt in this study.
Distribution of Novel Iron Regulatory Protein Hemojuvelin in Murine Tissues

Backgroung and Aims: Juvenile hemochromatosis is an early-onset iron overload disease that leads to severe organ damage typically before 30 years of age. In patients with juvenile hemochromatosis, several mutations have been identified in the gene encoding the protein designated hemojuvelin (HJV). Previous reports based on RT-PCR have shown that the expression pattern of HJV is wider in murine tissues than in human. To understand the mechanisms whereby HJV is connected to iron homeostasis, hemojuvelin mRNA and protein expression was studied at cellular level in different mouse tissues. Methods: In situ hybridization was used to determine the distribution of murine HJV mRNA. A specific riboprobe was constructed based on the murine HJV cDNA sequence. Hemojuvelin protein expression was detected immunohistochemically with a peroxidase-antiperoxidase method. Results: HJV mRNA and protein expression appeared to be rather restricted. Tissues that were positive with both methods included the kidney, pancreas, brain and liver. In addition, protein expression was studied in the endometrium, smooth muscle of the colon, ovario, submandibular gland and skeletal muscle, of which the endometrium and smooth muscle of the colon were defined as positive. HJV mRNA and protein expression were mainly negative in the heart, spleen, thymus and lung. The gastrointestinal tract showed negligible signal for mRNA, whereas in the stomach and duodenum weak staining for HJV protein was detected. Conclusions: The expression pattern of HJV suggests that HJV protein may play important roles in various tissues – not only in those classically considered the most important ones for regulation of iron homeostasis.
Research on reasons and effects of compensation control on executives of state-owned enterprises

There has been controversies on the sky-high compensation of state-owned enterprise(SOE) executives over the years; and the Ministry of Finance issued a series of governmentimposed pay curbs on their compensation to limit the pay of the state-owned enterprise executives. However, the effect of such regulations are difficult to assess. Based on the literature research, possible effects by the limit pay order are probed into, then the underlying reasons are analyzed, and then the corresponding consequences are discussed. and in the end reasonable and feasible suggestions put forward. Keywords—executive compensation; limit pay order; SOE
Evaluation of serum lipid profile in children with nephrotic syndrome admitted in emergency ward of Government Tirunelveli Medical College and Hospital, India

Background: Nephrotic syndrome is a collection of clinical findings due to kidney damage. This includes protein in the urine, low blood albumin levels, high blood lipids, and significant edema. The objective of this study was to study the correlation between lipid profile and different types of nephrotic syndromeMethods: This cross-sectional study was done between March 2017 - October 2017 in the Department of Pediatrics, Tirunelveli Government Medical College. 40 cases of nephrotic syndrome between 1 to 12 years, which include all types of nephrotic syndrome. After history taking and clinical examination, blood samples were collected from the patients for lipid profile and analyzed with standard techniques.Results: In the 40 cases included in the present study mean serum albumin was low (mean = 2.212 gm %), mean total cholesterol (mean = 344.300 mg/dl) mean triglycerides (mean = 304.025 mg/dl) mean LDL (mean = 234.650 mg/dl) and mean VLDL (mean = 61.625 mg/dl) were elevated. HDL (mean = 46.07 mg/dl) with in normal limits. No significant changes observed.Conclusions: Serum cholesterol levels elevated significantly in relapse cases compared to the first episode. Serum cholesterol in SRNS cases shows statistically significant elevation compared to other types. LDL values were elevated in relapse cases compared to the first episode which were found out to be statistically insignificant. LDL values in SRNS cases show statistically significant elevation compared to first episodes and SDNS cases.