Miracle-dz/UniFAR-FTUs huggingface dataset:
Laparoscopic gastrectomy for locally advanced gastric carcinoma : long-term survival outcomes and prognostic factors

The purpose of this study was to evaluate the long-term outcomes of laparoscopic gastrectomy for patients with locally advanced gastric carcinoma. Of the 113 patients with locally advanced gastric carcinoma, 89 patients underwent laparoscopic total gastrectomy, while 24 patients underwent laparoscopic distal gastrectomy. There were no intraoperative or postoperataive 30-day death occurred. The 3-, and 5-year overall survival rates were 64% and 57% respectively. Univariate analysis revealed that pathological T status, pathological N status, tumor size and cancer cell differentiation status were statistically significant factors affecting overall survival. Earlier pathological T status and earlier pathological N status were significantly predictive for longer overall survival by multivariate analysis. In summary, laparoscopic gastrectomy can be considered as an alternative to traditional incision in patients with locally advanced gastric carcinoma. A prospective randomized controlled study on a larger scale is required to reach definitive conclusions regarding the efficacy of laparoscopic gastrectomy relative to other techniques.
Chapter # 11 IDENTIFYING VIOLENCE Research on Residential Care Girls ’ Recognition of Violence

The focus of this study is the violence descriptions and definitions of girls aged 14-18, who currently live in child protective institutions under the legal responsibility of the public authorities. A total of fifty-seven individual interviews for target group girls were conducted in nineteen residential care institutions in Bulgaria, Finland, Italy and Catalonia, Spain, in the spring of 2013. With the aim of drawing up a general picture of violence recognition among girls, we use a feminist theoretical discussion and definitions of violence to address the gendered and sexualized forms of violence described by the interviewed girls. In all of the countries concerned, the interviewed girls described physical, mental/psychological and verbal violence. The results of this study suggest that there are gaps in girls’ recognition of sexual violence and violence towards oneself. Girls in res idential care institutions are vulnerable to violence due to their age, gender, race and previous and often cumulative victimization with respect to various forms of violence. The study contributes to the development of participatory research methods within a feminist social psychology, by presenting a standpoint on the research making process, in particular by focusing on experiences of marginalized girls in residential care institutions and to their empowerment.
Do Not Exhibit Telomere Maintenance Mechanisms Culture In vitro Not Undergo Transformation after Long-term Derived Mesenchymal Stem Cells Do − Human Bone Marrow

Significant improvement in the understanding of mesenchymal stem cell (MSC) biology has opened the way to their clinical use. However, concerns regarding the possibility that MSCs undergo malignant transformation have been raised. We investigated the susceptibility to transformation of human bone marrow (BM)–derived MSCs at different in vitro culture time points. MSCs were isolated from BM of 10 healthy donors and propagated in vitro until reaching either senescence or passage (P) 25. MSCs in the senescence phase were closely monitored for 8 to 12 weeks before interrupting the cultures. The genetic characterization of MSCs was investigated through array-comparative genomic hybridization (arrayCGH), conventional karyotyping, and subtelomeric fluorescent in situ hybridization analysis both before and after prolonged culture. MSCs were tested for the expression of telomerase activity, human telomerase reverse transcriptase (hTERT) transcripts, and alternative lengthening of telomere (ALT) mechanism at different passages. A huge variability in terms of proliferative capacity and MSCs life span was noted between donors. In eight of 10 donors, MSCs displayed a progressive decrease in proliferative capacity until reaching senescence. In the remaining two MSC samples, the cultures were interrupted at P25 to pursue data analysis. Array-CGH and cytogenetic analyses showed that MSCs expanded in vitro did not show chromosomal abnormalities. Telomerase activity and hTERT transcripts were not expressed in any of the examined cultures and telomeres shortened during the culture period. ALT was not evidenced in the MSCs tested. BM-derived MSCs can be safely expanded in vitro and are not susceptible to malignant transformation, thus rendering these cells suitable for cell therapy approaches. [Cancer Res 2007;67(19):9142–9]
Web-based Supplementary Materials for “ Sample Size Determination for GEE Analyses of Stepped Wedge Cluster Randomized Trials ” by Li , Turner and Preisser Web Appendix

where the last equality is given by Theorem 8.9. 1 in Graybill (1983). Since both B − C and B + (T − 1)C are of the exchangeable form, it follows from (A.2) that Ri has four eigenvalues, λ1 = 1 − α0 + α1 − α2, λ2 = 1 − α0 − (T − 1)(α1 − α2), λi3 = 1 + (Ni − 1)(α0 − α1) − α2, λi4 = 1 + (Ni− 1)α0 + (T − 1)(Ni− 1)α1 + (T − 1)α2, with respective multiplicities (T − 1)(Ni− 1), Ni − 1, T − 1 and 1. For unbalanced Ni, λi3 and λi4 vary by cluster so depend on i; the subscript i will be suppressed under a balanced design with Ni = N .
Deep Learning in information analysis of electrocardiogram signals for disease diagnostics

With a rapid development of technology, new advanced methods for diseases detection become available. Thus, one possible way to diagnose the internal organs diseases is based on the information analysis of electrocardiogram signals. Since these signals contain information about various physiological processes taking place in the human body, it is possible to use them for health status evaluation. In this work, we propose a deep learning-based method for detecting various human diseases on the heart rate variability (HRV) data acquired from the electrocardiograms. We consider supervised and unsupervised approaches for training the models. In the first case, we use Convolutional Neural Networks and train them on the labeled HRV dataset. In the second case, we learn features from HRV data using Stacked Autoencoders and Restricted Boltzmann Machines, and then build a classifier on the obtained ones. The accuracy of the proposed models is evaluated on the dataset of labeled electrocardiograms with diagnosis in 14 different diseases. The final model demonstrates high performance with an average accuracy over 90% for most of the diseases. The source code of the models is written in Lua and available publicly.
Postpartum depression and child development " Depression has a profound impact on parameters of interpersonal behaviour

Depression has a profound impact on parameters of interpersonal behaviour (Lewinsohn et al. 1970; Libert & Lewinsohn, 1973; Teasdale et al. 1980). Studies of healthy mother–infant dyads have demonstrated that infants are highly sensitive to their interpersonal environment (Murray, 1988). It is, therefore, likely that postpartum depression, by virtue of its impact on maternal interpersonal functioning, will disrupt normal infant engagements with the mother and, as a consequence, impair infant developmental progress. In recent years a considerable body of research surrounding this question has accumulated.
Effect of Physical Form of the starter on Performance of Holstein Calves

Sixteen pre-weaning Holstein calves were paired based on gender and body weight (BW) and monitored for 7 wk to assess starter intake (sDMI), feed efficiency, growth rate, and weaning age as affected by feeding either a conventional ground or a commercial pelleted starter. Calves were weaned at 60 d of age if a minimum BW of 75 kg was obtained. Growth rate was estimated using a linear regression equation fitting BW against time for each calf. Polynomial equations were used to estimate the age at a daily consumption of 680 g starter and age at 75 kg BW. Weekly and average sDMI and BW, growth rate, and weaning age were not significantly affected by the processing method of the calf starter. Calves on both starters required the same time to attain 75 kg BW. Results supported the hypothesis that the easy-to-access, ground calf starter is as effectual as its more costly, pelleted form in promoting adequate starter intake and growth rate needed for the early weaning of dairy calves. (
How to Find the Missing Link between Cognitive Decline and Stroke in the Context of Chronic Renal Failure

In a study published this year [1], we used structural, cognitive, and physiological parameters to measure how the brain responds to ischemic stroke in the context of chronic renal failure. Our study, which utilized a prospective cohort of 431 participants, showed that 24 months following stroke, those with chronic renal failure (CRF) as determined by creatinine clearance (CCI < .60 ml/min) had a stronger association with cognitive decline than those without kidney dysfunction. Two known biomarkers of the aging brain, white matter hyperintensities (WMH) and cortical atrophy, along with different measures of cognitive impairment, were found to have a positive correlation with pre-stroke impaired renal function [1]. Previous studies have shown the strong association between kidney dysfunction, stroke and cognitive impairment [1-6]. However, researchers have not yet determined the link between CRF and cognitive decline in patients recovering from stroke. Our study expanded on previous works, including the widely cited Reasons for Geographic and Racial Differences in Stroke (REGARDS) study, which showed a strong association between cognitive impairment and kidney decline[1], [3,5]. In this commentary, we evaluate different mechanisms in which CRF may affect cognitive function post stroke and propose pathways through which CRF may inhibit brain recovery, helping us to narrow our focus on specific pathophysiological processes that may yield new approaches to therapy in future clinical trials.
Impact of textile wastewater on germination and growth of Pisum sativum L.

The use of industrial waste water for irrigation purposes has emerged an important way to utilize its nutrients and removal of its pollutant load by growing tolerant plant species. The present study is an attempt to find out the ways in which the otherwise harmful industrial effluent can be beneficial used especially for agricultural purposes. The present study has been made to evaluate the output of textile effluent on germination and crop growth using Pisum sativum L. var Arkel. Plants were raised first in petri dishes and then in plastic pots in triplicate and irrigated with various concentrations of effluent. It was suggested that waste water from textile factory could be utilized for irrigation purposes after proper dilution and may contribute, at least in part towards solving the problem of textile effluent disposal. However, such recommendation needs some more extensive work to minimize the risk.
Sowing Dates and Nitrogen Fertilizer Levels Effect on Grain Yield and its Components of Different Wheat Genotypes

Two field experiments were conducted at Experimental Research Center, Faculty of Agriculture, Cairo University, Egypt during 2011/2012 and 2012/2013 seasons to determine the effect of different sowing dates and nitrogen levels on growth and grain yield and its components of some wheat genotypes. Wheat crop genotypes responded differently to the three factors for various characters (number of spikes/m, spike length, grain weight/spike, 1000-grain weight, harvest index and grain yield/fed.) produced the highest values at early sowing (25 November) as well as at 100 kg N/fed. in both seasons. Late sowing (December) and low nitrogen application significantly declined yielding capacity of wheat genotypes. Either L.R. -62 or Sids 1 produced highest grain yield performed better in term of grain yield as compared to other genotypes in both seasons, respectively. Moreover, all tested genotypes produced highest grain yield when planted early in 25 November and application of 100 kg N/fed.
PASSIVE IMMUNITY TO WHITE SPOT SYNDROME VIRUS (WSSV) IN PENAEUS MONODON TREATED WITH MONOCLONAL ANTIBODIES OF THE HETEROLOGOUSLY PRODUCED VP28 VIRAL ENVELOPE PROTEIN

White spot syndrome virus (WSSV) is a highly pathogenic and prevalent virus affecting shrimp culture worldwide including Taiwan. In the present study, the viral envelope protein, VP28, gene of the WSSV was cloned into a pET28a expression vector. VP28 was expressed as a protein with a 6-histidine tag in Escherichia coli and purified by a Ni-NTA column. Antiserum was raised against this recombinant VP28 protein in BALB/C mice, and it recognized the VP28 protein in purified virions and recombinant proteins. The antiserum was mixed with arginine (100 ppm), lysine (168 ppm), and phenylalanine (88 ppm), and the titer of the antibody was 20,000-fold/ml. A series of monoclonal antibodies was tested for their ability to neutralize WSSV infectivity by immersion and oral administration. Our results proved that the antibody developed against the VP28 protein could efficiently prevent or control WSSV infection in post-larval and juvenile stages by immersion and oral administration. Furthermore, the postlarvae obtained from the antibody-treated group had > 60% survival after 20 days of challenge, illustrating that the antibody produced from heterologously expressed VP28 may specifically provide passive immunity against the WSSV pathogen. Therapeutic studies illustrated that shrimp losses could be controlled within 5 days of infection using this monoclonal antibody. These results should be considered in the light of the potential application of anti-VP28 antibodies as a prophylactic drug in aquaculture.
Localization of Cadmium metal ion in Lemna polyrhiza L. using SEM morphology and EDX analysis

Cadmium is considered to be one of the most toxic metals even at lower concentration. The significance of toxic concentration of cadmium provided individually was investigated in order to assess the effect of metal interaction in Lemna polyrhiza L. The objective of the present study was to evaluate the effect of Cadmium (Cd) ion and possible variations in its tissue after 6 days exposure to 0.5 ppm Cd solution. Lemna polyrhiza L. was cultured in hoagland medium supplemented with 0.5 ppm Cd concentration and harvested after 6 day. To scrutinize anatomical abnormalities SEMEDX analysis were carried out for cadmium treated plants (0.5 ppm) for both the test and control plants. Surface morphology of control plant showed non shiny, porous, non crystalline surface with fixed shape and was found to maintain evenness throughout the surface where as SEM images of cadmium treated samples revealed shiny, crystalline and white surface which is evidence that cadmium have got absorbed on the surface. Furthermore, more porous nature of control samples was the indications of the plant to be a good bioindicator of cadmium contaminated environment. The results obtained inveterate that Lemna polyrhiza L. is heavy metal accumulator and thus SEM-EDX applications in natural habitat open up broad prospects for future studies of metal ecotoxicity.
OF THE CASE OF HYPEROSTOSIS IN THE SILVER BREAM , Pagrus auratus ( FORSTER , 1801 ) SAMPLED FROM WATERS AROUND NEW ZEALAND

In this study a case of hyperostosis was studied in teleost fish Pagrus auratus sampled from Bay of Plenty and the North Eastern coast of New Zealand. New characteristics of the hyperostosis (position and shape) were added to those previously given for the species Pagrus auratus. The hyperostosis was found in the neural spine of the sixth caudal vertebra and the haemal spine of the sixth, seventh, and eighth caudal vertebrae. The present study showed that shape of hyperostosis in the silver bream could be irregular-spherical, spherical, elongated, pear-shaped, and elongated pear-shaped.
Chapter 6 Treatment of Neuropathic Pain in Brachial Plexus Injuries

Brachial plexus injuries are commonly followed by chronic pain, mostly with neuropathic characteristics. This is due to peripheral nerve lesions, particularly nerve root avulsions, as well as upper limb amputations, and complex regional pain syndrome (CRPS). The differential diagnosis between CRPS and neuropathic pain is essential as the treatment is different for each of them. Medical treatments are the first step, but for refractory cases there are two main types of surgical alternatives: ablative techniques and neuromodulation. The first group involves destruction of the posterior horn deafferented neurons and usually provides a better pain control but has a 10% complication rate. The second group provides pain control with function preservation but with limited effectiveness. Each case has to be thoroughly evaluated to apply the treatment modality best suited for it.
Prevalence of Neospora caninum using Milk and Serum ELISA and its Hematological Effect in Dairy Buffaloes

Received: Revised: Accepted: Published online: December 11, 2017 December 28, 2017 December 30, 2017 March 28, 2018 The current study compared the performance of serum and milk ELISA in determining Neospora caninum prevalence in lactating Nili-Ravi buffaloes. Overall, 64 milk samples (n=57 individual milk samples; n=7 bulk milk samples) collected from buffaloes of districts Lahore and Narowal were tested for anti-N. caninum antibodies using milk iscom ELISA. The same animals were evaluated serologically using serum cELISA for this purpose. Furthermore, hematological profiling of 50 seropositive and 15 seronegative buffaloes was performed to appraise any effect of N. caninum seropositivity on the hematological parameters of the host. Resultantly, milk ELISA detected lesser milk samples positive i.e., 61.64% (±12.6, 95% C.I. 35/57) for N. caninum against higher seropositivity (76.6% ±7.16, 42/57) by serum cELISA. The agreement level (Kappa ratio=0.568 & R =0.769) between the performance of two assays was found good. General Linear Model analysis of hematological parameters reflected significantly (P<0.05) lower monocyte count but higher blood glucose levels in seropositive buffaloes associated with different seasons. It was concluded that, owing to the limitations of the milk ELISA (also lower sensitivity than cELISA) it is best suited for finding prevalence in lactating dairy herds having substantial number of infected animals but in general, serum ELISA is best for prevalence studies. While, decreased monocyte count and higher blood glucose levels in the affected animals was observed, which may be attributed to persistent inherent stress of infection on the host. ©2017 PVJ. All rights reserved
The income effect of CAP subsidies: implications of distributional leakages for transfer efficiency in Italy

Enhancing farm income level is one of the main purpose of the Common Agricultural Policy (CAP). The ability to reach such a goal can be measured in terms of transfer efficiency, that is affected by the presence of distributive leakages through the agro-food system. The present work aims to shed light on the income distributional effects of the main forms of CAP subsidies in Italy over the period 2008–2014: single payment scheme, coupled payment and second pillar aids. To this aim, an Arellano–Bond linear dynamic panel-data estimation (based on a database provided by the Italian FADN) is performed. Results show that all the main types of CAP support have a significant income effect, even though some relevant differences occur between decoupled and coupled components of direct payments received by Italian farmers as a consequence of distributional leakages.
Multi-label Hate Speech and Abusive Language Detection in Indonesian Twitter

Hate speech and abusive language spreading on social media need to be detected automatically to avoid conflict between citizen. Moreover, hate speech has a target, category, and level that also needs to be detected to help the authority in prioritizing which hate speech must be addressed immediately. This research discusses multi-label text classification for abusive language and hate speech detection including detecting the target, category, and level of hate speech in Indonesian Twitter using machine learning approach with Support Vector Machine (SVM), Naive Bayes (NB), and Random Forest Decision Tree (RFDT) classifier and Binary Relevance (BR), Label Power-set (LP), and Classifier Chains (CC) as the data transformation method. We used several kinds of feature extractions which are term frequency, orthography, and lexicon features. Our experiment results show that in general RFDT classifier using LP as the transformation method gives the best accuracy with fast computational time.
Anti-inflammatory, Antioxidant Activities and Fatty Acid Profile of Three Hydrolysates from Liza aurata By-product Influenced by Hydrolysis Degree

The chemical composition, functional properties, antioxidant activity (reducing power, DPPH•, DNA nicking test, ferrous chelating and s-carotene bleaching assays) and anti-inflammatory (anti-5-lipoxygenase (5-LOX)) activities comparison between undigested Liza aurata head protein (ULAHP) and its protein hydrolysates (LAHPHs), prepared by Neutrase, testing three degrees of hydrolysis (DH), was evaluated. This study was designed to examine how the increase of degree of hydrolysis was effective for destroying protein-lipid complexes LAHPHs. Results showed that fatty acids and lipid content were distributed unequally between the fractions and the distribution was affected by the DH. Oleic acid is the most abundant in the hydrolysate fraction. The percentage of oleic acid in the LAHPHs range between 34.6% and 36.6%. The protein content of LAHPHs ranged from 61.72% to 63.44%, and the highest value was obtained in DH1. In terms of antioxidant activities, it was found that DH3 exhibited better capacities (DPPH: 72.03%, ferrous chelating: 97.14%, reducing power: 1.621 and β-carotene bleaching inhibition: 58.33%) and the activity increased as the DH increased. However, the interfacial activities and the DH are inversely proportional. Moreover, LAHPHs showed powerful inhibitory activity towards the enzyme 5-LOX. Overall, these results indicated that proteins hydrolysates from L. aurata by-product are valuable source of bioactive peptides and show promise as functional foods ingredients and biotechnological application.
Undrained shear strength of methane hydrate-bearing sand ; preliminary laboratory results

Methane hydrates are promising energy resources of natural gas that form at high pressure and low temperature in seafloor sediments and permafrost regions. In hydrate accumulations, understanding of the physical and mechanical properties of hydrate bearing sediments is practically important and also an essential input into accurate numerical simulations. An experimental program investigating the shear strength and volume change characteristics of gas hydrate bearing sand was undertaken using undrained triaxial testing. The results indicate strength of hydrate bearing sand is strongly related to how the hydrate has formed within the sediment. RÉSUMÉ Les hydrates de méthane sont des ressources prometteuses d’énergie. Ce sont des gaz naturels qui se forment à hautes pressions et basses températures dans les sédiments sous-marins et les régions de pergélisol. Dans les accumulations d’hydrates, la compréhension des propriétés physiques et mécaniques des sédiments contenant des hydrates est importante en pratique, mais est aussi essentielle pour effectuer des simulations numériques précises. Un programme expérimental s’intéressant à la résistance au cisaillement et aux caractéristiques des changements de volume des sables contenant des hydrates a été réalisé utilisant un test triaxial non-drainé. Les résultats indiquent que la résistance des sables contenant des hydrates est fortement liée à la façon dont les hydrates se sont formés dans les sédiments.