Miracle-dz/UniFAR-FTUs huggingface dataset:
The Extended Effects of the Life Review in Nursing Home Residents

To date, there is little information on the therapeutic effects of the life review beyond one year. This analysis followed fifty-two of 256 subjects who lived for at least three years in a nursing home. These participants received either a life review or friendly visit and took part in four repeated testings to determine the lasting effects of the life review at two and three years. Measures of integrity (life satisfaction, psychosocial well being, self-esteem) and despair (depression, hopelessness, and sucide intent) were used as pretest, posttest, and retest. Results showed a trend toward continued and by year three significant improvement over time in those who received the life review on measures of depression (t = −2.20, p < .03), life satisfaction (t = 2.51, p < .02), and self-esteem (t = −2.31, p < .03).
Airborne infection control in healthcare settings

Exposure of human beings to different airborne pathogens has resulted in the emergence of epidemics of respiratory infections. This airborne transmission becomes even more prevalent in healthcare settings because of overburdened hospitals and the presence of immunosuppressed patients. Airborne infection control measures include a three-pronged approach, namely administrative control, environmental control, and personal respiratory protection measures. To conclude, need of the hour is to assess the true contribution of airborne transmission to infection rates so that hospital administrators can implement appropriate control measures to keep respiratory infections under check.
Leucovorin Rescue of Enteric Lesions Induced by High-Dose Methotrexate: A Time-Related Study in Mice

In this study, different groups of mice were treated with a single high-dose of methotrexate or with a leucovorin-methotrexate association, and the changes in structure and cell types of the small intestine were studied histologically. The results suggested that leucovorin rescue diminished the degree of mitotic abatement induced by methotrexate in the first days after treatment, with better preservation of enteric structures and the cell type ratio.
Ascorbic Acid Effects on the Post-Disgorgement Oxidative Stability of Sparkling Wine

Post-disgorgement oxidative changes in bottle-fermented sparkling wines produced from Vitis vinifera and hybrid wine grape cultivars were examined with ascorbic acid and sulfur dioxide treatments added at disgorgement. Wines were stored 11 months at 21°C before analysis. Acetaldehyde was highest and browning was lowest in the sulfur dioxide treatments. Ascorbic acid after the storage period was 52% to 70% of the original amount added. Increasing SO 2 , when ascorbic acid was used, had little effect on ascorbic acid stability. When SO 2 was used, there was no benefit from including ascorbic acid. Ascorbic acid treatments reduced browning over the controls in two of the six cultivars. An accelerated storage test showed that the ascorbic acid treatments had the highest potential for browning if exposed to high levels of oxygen and increased temperature.
Splanchnic and mammary nitrogen metabolism by dairy cows fed dry-rolled or steam-flaked sorghum grain.

Objectives were to determine net release or uptake of alpha-amino N, ammonia N, and urea N across portal-drained viscera, liver, splanchnic, and mammary tissues of lactating Holstein cows (n = 8, 86 +/- 8 d in milk) fed alfalfa hay-based total mixed rations containing 40% dry-rolled or steam-flaked sorghum grain. The total mixed rations were offered at 12-h intervals in a crossover design. Blood samples were obtained from indwelling catheters in the portal, hepatic, and mammary veins and mesenteric or costoabdominal arteries, every 2 h for each cow and diet. Steam-flaking increased in vitro rate of starch hydrolysis compared with dry-rolled sorghum (66 vs. 25%). Diet did not alter dry matter intake (18.2 +/- 0.3 kg). Daily milk yield (27.6 +/- 0.8 kg), efficiency of production, and most milk components did not differ between diets, but fat yield was reduced (0.86 vs. 0.91 kg/d) by steam-flaked sorghum, and lactose concentration was increased (4.99 vs. 4.82%). Blood flows in portal and hepatic veins did not differ between diets. Steam-flaking tended to increase urea N cycling to the gut (162 vs. 95 g/d) compared with dry-rolling of sorghum, whereas net absorption of ammonia N and alpha-amino N across portal-drained viscera were decreased. Net mammary uptake of a-amino N increased more than 20% (83 vs. 67 g/d), resulting in a higher mammary extraction ratio (15 vs. 11%) for steam-flaked versus dry-rolled sorghum. Flaking of sorghum improved the efficiency of postabsorptive N metabolism by increasing urea N cycled to the gut and alpha-amino N uptake by the mammary gland.
Governing Genomics: New Governance Tools for New Technologies?

Abstract This paper considers some of the ‘new tools of governance’ and how they might apply to the life science industries. Through a study of a number of UK government–industry ‘task forces’ and recent world events in drug regulation it identifies two opposing trends in play and suggests that there are actually limits to the all pervasive notion of governance. Instead, the multi-faceted policy and regulatory situation that applies to the life sciences is leading to the existence of a government–governance continuum where different aspects of genomics and life science technologies sit at different points; contrasting the role of the state in controlling and framing the context for the implementation of innovations in life sciences through the regulatory system with the more participative forms of policy-making that are being fostered both to promote national competitiveness and encourage public acceptance of these new technologies.
microProtein Prediction Program (miP3): A Software for Predicting microProteins and Their Target Transcription Factors

An emerging concept in transcriptional regulation is that a class of truncated transcription factors (TFs), called microProteins (miPs), engages in protein-protein interactions with TF complexes and provides feedback controls. A handful of miP examples have been described in the literature but the extent of their prevalence is unclear. Here we present an algorithm that predicts miPs and their target TFs from a sequenced genome. The algorithm is called miP prediction program (miP3), which is implemented in Python. The software will help shed light on the prevalence, biological roles, and evolution of miPs. Moreover, miP3 can be used to predict other types of miP-like proteins that may have evolved from other functional classes such as kinases and receptors. The program is freely available and can be applied to any sequenced genome.
Differences in pathological gambling prevalence estimates: facts or artefacts?

The paper aims at investigating whether survey methodology has recently converged to justify the common practice of comparing prevalence estimates and interpreting differences within and between countries. To this end, prevalence studies of problem (PrG) and pathological gambling (PG) published in peer‐reviewed journals between 2000 and 2010 were critically reviewed. A systematic computer‐based literature search was conducted within various databases and major gambling journals. In a two‐step search process, a total of 39 studies reporting current prevalence data of non‐clinical national samples from different countries were identified. Analyses revealed wide ranges in estimated PrG/PG rates for adults, adolescents, and college students, whereas similar estimates were reported in two studies on PrG/PG in seniors. Despite the discussion on methodological consistency in the field of gambling research, comparability of the reported estimates was found to be still highly limited by major variation between studies with regard to survey description, administration format, exclusion criteria, assessment instrument, cut‐off scores, sample frame, and reference period. The interpretation of differences in PrG and PG prevalence estimates within and between countries may be improved by using valid and reliable instruments and by applying comparable survey methodology in well‐defined populations. Copyright © 2011 John Wiley & Sons, Ltd.
Fractional-order PID and active disturbance rejection control for active power filter

This paper proposed a fractional-Order PID controller and Active Disturbance Rejection Control (ADRC) method for current compensation of Active Power Filter (APF). The control method consists of two closed loop. One is a reference current tracking loop based on the ADRC controller, which can treat the internal and external uncertainties of the system as a whole for the convenient control. The other is the voltage controlling loop with the Fractional Order PID controller for more flexibility. By comparing with other control method, simulation results verify that the presented control method has excellent dynamic performance and strong robustness in the presence of model uncertainty as well as external disturbances.
Taylor Kuralı: Türkiye Üzerine Bir Değerlendirme

Calismanin temel amaci, para politikalarinin hangi degiskenlerin (enflasyon, uretim, kur) etkisi altinda belirlendigini ve bu surecte kural dogrultusunda hareket edilip edilmedigini ortaya koymaktir. Bu amac dogrultusunda, enflasyon hedeflenmesinin uygulandigi 2002 sonrasi icin Turkiye Cumhuriyeti Merkez Bankasi’nin (TCMB) geriye-donuk reaksiyon fonksiyonu tahmin edilmistir. Taylor kurali cercevesinde tahmin edilen reaksiyon fonksiyonu sonuclarina gore, Turkiye’de kisa vadeli faiz oranlari fiyat istikrarinin saglanmasi dogrultusunda kurala uygun degismektedir. Reaksiyon fonksiyonundan elde edilen sonuclar, TCMB’nin uyumcu politikalar izlemedigini gostermektedir. Elde edilen sonuclara gore TCMB faiz belirleme surecinde, enflasyon oraninin disinda uretim acigina ve doviz kuruna tepki vermektedir. Doviz kuruna verilen tepki, dalgali kur rejimiyle tutarli bir sekilde dusuk cikmistir. Bu sonuc, ilgili donem icin oncelikli amaci fiyat istikrarini saglamak olan TCMB’nin temel hedefi ile uyumludur.
Contribution to the knowledge of ecodiversity and density of tsetse (Glossinidae) and other biting flies (Tabanidae and Stomoxyinae) in the fly controlled-infested livestock/wild life interface of the Adamawa plateau-Cameroon

This present study seeks to contribute to knowledge of eco diversity and density of trypanosomiasis vectors in Adamawa Plateau of Cameroon. Ten Laveissiére traps were pitched in Alme and Faro Game Reserve and checked 24 hours every 4 days from December 2014 to June 2015. An overall scanty catch of 240 flies were recorded due to presence of impregnated Deltamethrin screens. Based on interview of herders, they were aware of fly dense areas such as Faro Game Reserve. Flies mean densities and Shannon-Weaver indices were: Glossina morsitans submorsitans (0.55f/t and 0.23) with bimodal peaks in January and May, Glossina tachinoides (0.13f/t and 0.10), with bimodal peaks in January and March, Tabanus spp. (0.51f/t and 0.18) with a unimodal peak in June and Stomoxys spp (0.10f/t and 0.03) with a unimodal peak in the month of May. Fly infestation of formerly controlled areas is increasing, with major re-invasion sources from protected areas.
Regulation of Longevity and Stress Resistance by Sch9 in Yeast

The protein kinase Akt/protein kinase B (PKB) is implicated in insulin signaling in mammals and functions in a pathway that regulates longevity and stress resistance in Caenorhabditis elegans. We screened for long-lived mutants in nondividing yeastSaccharomyces cerevisiae and identified mutations in adenylate cyclase and SCH9, which is homologous to Akt/PKB, that increase resistance to oxidants and extend life-span by up to threefold. Stress-resistance transcription factors Msn2/Msn4 and protein kinase Rim15 were required for this life-span extension. These results indicate that longevity is associated with increased investment in maintenance and show that highly conserved genes play similar roles in life-span regulation in S. cerevisiae and higher eukaryotes.
Genome‐wide association mapping of heritable temperament variation in the Tennessee Walking Horse

Temperament is a key criterion in the selection of horses for both leisure and competitive riding to ensure optimal performance and safety. The Tennessee Walking Horse (TWH) is described as a calm, docile breed and is often used as a trail, show and pleasure horse. However, among horse owners and caretakers, there are anecdotes supporting familial and disciplinal typical behaviors and personalities. To investigate the contribution of genetics to temperament, we collected a behavior questionnaire, brief training history and identifying information for 276 TWH, as well as blood or hair samples for DNA. Factor analysis was conducted on the 20‐item questionnaire for the set of 216 horses that met inclusion thresholds. Factor analysis identified four temperament factors in TWH: ‘anxious’, ‘tractable’, ‘agonistic’ and ‘gregarious’. These four factors account for 64% of the total trait variance. DNA from 113 TWHs were selected and genotyped using the Equine SNP70 bead chip for three separate genome‐wide association studies (GWAs) using the factor 1‐anxious, factor 2‐tractable and factor 3‐agonistic scores as the phenotype. Quantitative association analysis identified significant candidate loci for each factor that warrant further investigation.
ELECTRONIC SELF-CHECKOUT SYSTEM VS CASHIER OPERATED SYSTEM: A PERFORMANCE BASED COMPARATIVE ANALYSIS

Customers want fast checkout systems. Retailers are always searching for ways to improve store checkout systems. This study compared the cashier checkout and the electronic selfcheck out systems. Data for this study were collected by observations of checkout processes at Wal-Mart Super Centers in the Jackson, Mississippi, area. Formulated research questions were statistically tested employing the independent samples t-tests and the chi square test for independence. Results of these analyses showed that consumers preferred the cashier checkout system to the electronic self-checkout system, although shoppers also want to learn how to use the new self-checkout technology. Further studies were suggested on methods of introducing new Point of Sale technology to consumers, and ways to help managers compare costs of checkout systems.
The Effects of Thermal Preconditioning on Tissue Susceptibility to Histotripsy

Histotripsy is a non-invasive ablation method that mechanically fractionates tissue by controlling acoustic cavitation. Previous work has shown that tissue mechanical properties play a significant role in the histotripsy process, with stiffer tissues being more resistant to histotripsy-induced tissue damage. In this study, a thermal pretreatment strategy is proposed in order to precondition tissues prior to histotripsy. We hypothesize that a thermal pretreatment can be used to alter tissue stiffness by modulating collagen composition, thus changing tissue susceptibility to histotripsy. More specifically, we hypothesize that tissues will soften and become more susceptible to histotripsy when preheated at ~60°C due to collagen denaturing, but that tissues will rapidly stiffen and become less susceptible to histotripsy when preheated at ~90°C due to collagen contraction. To test this hypothesis, a controlled temperature water bath was used to heat various ex vivo bovine tissues (tongue, artery, liver, kidney medulla, tendon, and urethra). After heating, the Young’s modulus of each tissue sample was measured using a tissue elastometer, and changes in tissue composition (i.e. collagen structure/density) were analyzed histologically. The susceptibility of tissues to histotripsy was investigated by treating the samples using a 750 kHz histotripsy transducer. Results demonstrated a decrease in stiffness and an increase susceptibility to histotripsy for tissues (except urethra) preheated to 58°C. In contrast, preheating to 90°C increased tissue stiffness and reduced susceptibility to histotripsy for all tissues except tendon, which was significantly softened due to collagen hydrolysis into gelatin. Based on these results, a final set of experiments was conducted to demonstrate the feasibility of using high intensity focused ultrasound (HIFU) to provide the thermal pretreatment. Overall, the results of this study demonstrate the initial feasibility of a thermal pretreatment strategy to precondition tissue mechanical properties and alter tissue susceptibility to histotripsy. Future work will aim to optimize this thermal pretreatment strategy in order to determine if this approach can be practically applied for specific clinical applications in vivo without causing unwanted damage to surrounding or overlying tissue. Histotripsy demonstrated that tongue, artery, and urethra were less susceptible to histotripsy-induced tissue damage after heating at 90°C for 4 hours while tendon was more susceptible to histotripsy after heating. All tissues became more susceptible to histotripsy after 8 and 12 to 4
Patterns of spatial genetic structuring in a hydropsychid caddisfly (Cheumatopsyche sp. AV1) from southeastern Australia

We assessed levels of mitochondrial genetic spatial structuring in the hydropsychid caddisfly Cheumatopsyche sp. AV1 in southeastern New South Wales, Australia. No significant spatial structuring was detected within or between catchments using analysis of molecular variance, and nested clade contingency analysis suggested no strong relationship between haplotypes and geographical location, at any clade level. However, tests for association among haplotypes incorporating geographical distance in the nested clade analysis, revealed patterns of historical range expansion and recent restricted gene flow. Most likely, population fragmentation preceded range expansion, although subsequent recontact and gene flow among the previously sundered populations has apparently obscured the geographical signature of the former fragmentation. Taken together, our analyses suggest that a number of populations fragmented during the Pleistocene evolved in isolation for a time and subsequently expanded into secondary contact. Since expansion, there has apparently been substantial (albeit somewhat restricted) dispersal and gene flow of adult female Cheumatopsyche sp. AV1, throughout the study area.
Model of Coordination of Transport Processes According to the Concept of Sustainable Development

Sustainable development means that it is possible to organize current needs in the way, which does not eliminate the possibility of organizing the same needs in future. It is the ability to maintain a balance of a certain process or state in any system. In business activities, it is the ability to maintain a balance between three areas: economical, ecological and social one. In this article, the possibility of exploiting concept of sustainable development in organizing transport processes is presented. Additionally, the model of coordination of transport processes within companies is discussed, as well as its pros and cons.
Sexual Dimorphism of Bizygomatic distance & Maxillary sinus using CT Scan

An incomplete skeleton especially skull is a great challenge for Forensic anthropologists for age & sex estimation. But sometimes denser bones are often recovered intact eg. zygomatic bone, maxillary sinus. Therefore this study tries to use the alternate methods for gender estimation by using measurements of denser areas of such unknown skull especially bizygomatic distance.The aim of this study was to investigate whether the bizygomatic distance, AP diameter & width of the maxillary sinus & intermaxillary distance could be used for determination of gender using CT scan. 191 cases were studied, from M.P. region, of which 106 were males and 85 were females. All the measurements were taken from series of CT Head images in axial images on DICOM viewing software in computer.The data was statistically analyzed by using Graph pad prism.Unpaired Student t-test was carried out and calculated for each data separately. Analysis of variance was also done & F- value were calculated. A statistically significant difference with p<0.0001 was observed in the bizygomatic distance with mean±SD of 9.55±0.41cm for male & 9.262±0.52 for female. The strongest correlated variable with bizygomatic distance was the intermaxillary distance (r = 0.3037) in male & AP diameter of sinus (r = 0.5980) in female.We can conclude that Computerized Tomography measurements of bizygomatic distance & maxillary sinus dimensions may be useful to support gender determination in forensic medicine when other methods are inconclusive.
Health Beliefs of First-degree Relatives of Individuals With Colorectal Cancer and Participation in Health Maintenance Visits: A Population-based Survey

The occurrence of colorectal cancer (CRC) in two or more close relatives by chance is relatively common, and a family history of CRC is recognized as a risk factor for CRC. The purpose of this study was to identify variables associated with participation of first-degree relatives (FDRs) of individuals diagnosed with CRC in health maintenance visits with healthcare providers. Data were collected from a survey mailed to patients (n = 1081) diagnosed with CRC under age 60 years who were identified by the Pennsylvania Cancer Registry. An enclosure was also included in the mailing for their FDRs. Of the 1,081 people contacted, 174 registry patients and 90 FDRs agreed to participate in this study. A logistic regression model was built, and constructs of the Health Belief Model and selected sociodemographic variables (age, gender, level of education) were entered with participation in health maintenance visits as the dependent variable. The analysis revealed 2 Health Belief Model variables (perceived barriers and perceived seriousness) and 1 sociodemographic variable (level of education) as predictive of an FDR’s participation in health maintenance visits. The findings from this study suggest that FDRs of individuals with CRC do not perceive that they are at risk for CRC, despite their family history. These data also provide the foundation for future studies aimed at the development of interventions to increase awareness of the importance and benefits of screening for relatives of individuals with CRC.
Expression of the transcription factor Olig2 in proliferating cells in the adult zebrafish telencephalon

The telencephalon of the adult zebrafish is highly proliferative: Dividing cells are found along the entire ventricular zone and in the parenchyma. Here, we investigated the relation of proliferating cells in the telencephalic parenchyma to the oligodendrocyte lineage. We find at least three different cell types of the oligodendrocyte lineage (olig2‐and sox10‐positive) in the parenchyma of the telencephalon: Proliferating progenitors (PCNA‐positive), including a subpopulation of slowly dividing progenitors (long term label‐retaining), as well as mature oligodendrocytes (Mbp‐positive) and presumptive quiescent OPCs (neither Mbp‐positive nor proliferating). Furthermore, in the ventricular zone (in and ventral to the RMS), two different subpopulations of olig2‐positive cell populations are present. Since these ventricular olig2‐positive cells do not express the oligodendrocyte marker sox10, it is not clear whether these cells indeed belong to the oligodendrocyte lineage. Taken together, we detected at least five different classes of olig2‐positive cells in the telencephalon of the adult zebrafish. Developmental Dynamics 239:3336–3349, 2010. © 2010 Wiley‐Liss, Inc.