Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis of the dependence between the number of accidents at workplaces that involve scaffolding and changes in work efficiency

The purpose of the article is to present the occupational characteristics of people injured in accidents at workplaces that use construction scaffolding. The results obtained from the analysis of occupational accidents involving construction scaffolding, which took place in five Polish voivodships: Dolnoslaskie, Lubelskie, Lubuskie, Mazowieckie and Wielkopolskie between 2010-2015, were presented. 177 occupational accidents were analysed. On the basis of post-accident protocols, the following occupational characteristics of employees who suffered from accidents were identified: the age of the victim, the time of day when the accident happened and the season of the year. In turn, on the basis of a review of the subject literature, the course of changes in an employee's performance during the day, week and calendar year was determined. The relation between efficiency and the identified occupational characteristics of the injured parties was determined.
Principal component analysis and brain-based predictors of emotion regulation in anxiety and depression

Abstract Background Reappraisal, an adaptive emotion regulation strategy, is associated with frontal engagement. In internalizing psychopathologies (IPs) such as anxiety and depression frontal activity is atypically reduced suggesting impaired regulation capacity. Yet, successful reappraisal is often demonstrated at the behavioral level. A data-driven approach was used to clarify brain and behavioral relationships in IPs. Methods During functional magnetic resonance imaging, anxious [general anxiety disorder (n = 43), social anxiety disorder (n = 72)] and depressed (n = 47) patients reappraised negative images to reduce negative affect (‘ReappNeg’) and viewed negative images (‘LookNeg’). After each trial, the affective state was reported. A cut-point (i.e. values <0 based on ΔReappNeg-LookNeg) demarcated successful reappraisers. Neural activity for ReappNeg-LookNeg, derived from 37 regions of interest, was submitted to Principal Component Analysis (PCA) to identify unique components of reappraisal-related brain response. PCA factors, symptom severity, and self-reported habitual reappraisal were submitted to discriminant function analysis and linear regression to examine whether these data predicted successful reappraisal (yes/no) and variance in reappraisal ability. Results Most patients (63%) were successful reappraisers according to the behavioral criterion (values<0; ΔReappNeg-LookNeg). Discriminant function analysis was not significant for PCA factors, symptoms, or habitual reappraisal. For regression, more activation in a factor with high loadings for frontal regions predicted better reappraisal facility. Results were not significant for other variables. Conclusions At the individual level, more activation in a ‘frontal’ factor corresponded with better reappraisal facility. However, neither brain nor behavioral variables classified successful reappraisal (yes/no). Findings suggest individual differences in regions strongly implicated in reappraisal play a role in on-line reappraisal capability.
Performance and Symptom Validity Testing in Pediatric Assessment: A Review of the Literature

ABSTRACT There has been an increased recognition that validity testing is an integral component of evaluations conducted with youth. The incorporation of validity testing provides an objective basis for placing confidence in the test data as an accurate assessment of the child’s or adolescent’s current ability level and/or an accurate indication of the child’s or adolescent’s current symptoms or behavioral functioning. The use of objective performance validity and symptom validity is consistent with the current emphasis of data-driven decision-making. This paper provides a review of the literature on performance and symptom validity tests for children and adolescents. The strengths and limitations of the available validity tests are discussed, and recommendations for use in pediatric assessments are provided.
Permanent His Bundle Pacing for Cardiac Resynchronization Therapy in Patients With Heart Failure and Right Bundle Branch Block

Background: Cardiac resynchronization therapy utilizing biventricular pacing is an effective therapy for patients with left ventricular (LV) systolic dysfunction, left bundle branch block, and heart failure. Benefits of biventricular pacing may be limited in patients with right bundle branch block (RBBB). Permanent His bundle pacing (HBP) has recently been reported as an option for cardiac resynchronization therapy. The aim of the study was to assess the feasibility and outcomes of HBP in patients with RBBB and heart failure. Methods: HBP was attempted as a primary or rescue (failed LV lead implant) strategy in patients with reduced LV ejection fraction, RBBB, QRS duration ≥120 ms, and New York Heart Association class II to IV heart failure. Implant characteristics, New York Heart Association functional class, and echocardiographic data were assessed in follow-up. Results: Mean age was 72±10 years, female 15%, with an average LV ejection fraction of 31±10%. HBP was successful in 37 of 39 patients (95%) with narrowing of RBBB in 78% cases. His capture and bundle branch block correction thresholds were 1.1±0.6 V and 1.4±0.7 V at 1 ms, respectively. During a mean follow-up of 15±23 months, there was a significant narrowing of QRS from 158±24 to 127±17 ms (P=0.0001), increase in LV ejection fraction from 31±10% to 39±13% (P=0.004), and improvement in New York Heart Association functional class from 2.8±0.6 to 2±0.7 (P=0.0001) with HBP. Increase in capture threshold occurred in 3 patients. Conclusions: Permanent HBP was associated with significant narrowing of QRS duration and improvement in LV function in patients with RBBB and reduced LV ejection fraction. Permanent HBP is a promising option for cardiac resynchronization therapy in patients with RBBB and reduced LV ejection fraction.
Forgiveness and friendship protect adolescent victims of bullying from emotional maladjustment

Background: Adolescent victims of bullying often present high levels of maladjustment, such as depression, anxiety, and the inability to manage anger. Both forgiveness and friendship have been found to be moderating agents for the debilitating psychological effects seen in the victims of bullying. Our aim was to explore the roles of forgiveness and friendship in the psychological adjustment of victimised youths. Method: The sample was composed of 2,105 adolescents (age range 13‐20) recruited from central and southern Italy. We collected information on bullying, forgiveness, friendship, depression, anxiety and anger. Results: We found that more victimisation and not having a best friend had an additive effect on maladjustment. Moreover, adolescents who scored lower in forgiveness were more likely to be depressed and angry. Discussion: Our data provide confirmation that forgiveness is a protective factor for Italian adolescents, as is friendship, although they do not operate as interactive protective factors. Given that forgiveness is so significantly associated with wellbeing and the fact that it can be taught and enhanced in both clinical and school settings, it would be worthwhile to include work on forgiveness in prevention and treatment programmes. &NA; El perdón y la amistad protegen a los adolescentes víctimas de acoso escolar de la inadaptación emocional. Antecedentes: los adolescentes víctimas de acoso escolar presentan a menudo niveles altos de depresión y de ansiedad y problemas en el manejo de la ira. Se ha observado que tanto el perdón como la amistad funcionan como moderadores de los efectos psicológicos del acoso. Nuestro objetivo fue explorar las funciones del perdón y la amistad en la adaptación de jóvenes víctimas de acoso escolar. Método: se han utilizado datos sobre el acoso, el perdón, la amistad, la depresión y la ira de una muestra de 2.015 adolescentes, de entre 13 y 20 años, de centros de educación de Italia centro‐meridional. Resultados: se encuentra que el perdón y no tener un amigo afectan a la inadaptación de forma aditiva. Además, los adolescentes con puntuaciones bajas en perdón tienden a deprimirse y enfadarse. Conclusiones: nuestros datos confirman que tanto el perdón como la amistad funcionan como factores de protección para los adolescentes italianos, aunque no de forma interactiva. Dada la importancia del perdón para el bienestar y puesto que se puede enseñar y potenciar en escuelas y fuera de ellas, conviene incluir el perdón en programas de prevención y tratamiento.
An improved CUDA-based hybrid metaheuristic for fast controller of an evolutionary robot

This paper proposes a novel parallel hybrid training approach to conceive an evolutionary robot. The proposed design aims to provide efficient behaviours to perform its tasks in a complex area such as walking toward a hidden destination. Embedded in robot brain, this training and evolution combination is typically accomplished by evolving considerable recurrent neural networks (RNNs) using an evolutionary strategy (ES). The effectiveness of this proposal is improved by employing CUDA technology that executes the evolutionary process of RNNs in a parallel way. The modifications applied are indicating to meet CUDA requirements in terms of CPU/GPU cooperation and memory management. Using a set of experiments performed by GPGPU-based physical simulator named open dynamics engine (ODE) and CUDA-based evolution, the effectiveness of the proposed parallel evolutionary training technique was validated for real movements of humanoid robots. This validation showed a promising speed-up, since this field requires very high powerful computational resources.
Theta-modulation drives the emergence of connectivity patterns underlying replay in a network model of place cells

Place cells of the rodent hippocampus fire action potentials when the animal traverses a particular spatial location in any environment. Therefore for any given trajectory one observes a repeatable sequence of place cell activations. When the animal is quiescent or sleeping, one can observe similar sequences of activation known as replay, which underlie the process of memory consolidation. However, it remains unclear how replay is generated. Here we show how a temporally asymmetric plasticity rule during spatial exploration gives rise to spontaneous replay in a model network by shaping the recurrent connectivity to reflect the topology of the learned environment. Crucially, the rate of this encoding is strongly modulated by ongoing rhythms. Oscillations in the theta range optimize learning by generating repeated pre-post pairings on a time-scale commensurate with the window for plasticity, while lower and higher frequencies generate learning rates which are lower by orders of magnitude.
Supervisory acceleration of convergence for homogeneous systems

ABSTRACT The rate of convergence to the origin for a chain of integrators stabilised by homogeneous feedback is accelerated by a supervisory switching of control parameters. The proposed acceleration algorithm ensures a fixed-time convergence for otherwise exponentially or finite-time stable homogeneous closed-loop systems. Bounded disturbances are taken into account. The results are especially useful in the case of exponentially stable systems widespread in practice. The proposed switching strategy is illustrated by computer simulation.
Hepatectomy plus adjuvant transcatheter arterial chemoembolization improves the survival rate of patients with multicentric occurrence of hepatocellular carcinoma

The aim of the present study was to evaluate the role of hepatectomy plus adjuvant transcatheter arterial chemoembolization (TACE) in patients with multicentric occurrence (MO) or intrahepatic metastases (IM) of hepatocellular carcinoma (HCC). Patients with multifocal HCC who underwent hepatic resection only (HR) or HR plus adjuvant TACE (HRT) between January 2005 and December 2015 were divided into MO or IM groups. The patient characteristics and outcomes were retrospectively analyzed. A total of 103 patients (59 and 44 in the MO and IM groups, respectively) were included in the analysis. The 1-, 3- and 5-year overall survival (OS) rates were 92.7, 76.8 and 56.8% for the MO group, and 93.1, 41.6 and 18.5% for the IM group, respectively (OS, P=0.001), and the 1-, 3- and 5-year disease-free survival (DFS) rates were 84.1, 44.6 and 40.5% for the MO group and 51.7, 22.5 and 15.0% for the IM group, respectively (DFS, P<0.001). In the subgroup analysis, the overall survival were significantly better in the MO-HRT group compared with those in the MO-HR group (P=0.019), which was also observed between the IM-HRT and IM-HR groups (P=0.132). Furthermore, the 1-, 3- and 5-year OS demonstrated non-significant differences between patients with <3 and ≥3 tumors in the MO-HR group (P=0.300), but significantly reduced OS for patients with ≥3 tumors in the IM-HR group compared with that for patients with <3 tumors (P=0.132). In conclusion, surgical resection combined with adjuvant TACE may result in significantly increased survival rates of patients with MO-HCC. Tumor number should not be an absolute contradiction to hepatectomy in patients with MO-HCC.
Are the metabolic benefits of resistance training in type 2 diabetes linked to improvements in adipose tissue microvascular blood flow?

The microcirculation in adipose tissue is markedly impaired in type 2 diabetes (T2D). Resistance training (RT) often increases muscle mass and promotes a favorable metabolic profile in people with T2D, even in the absence of fat loss. Whether the metabolic benefits of RT in T2D are linked to improvements in adipose tissue microvascular blood flow is unknown. Eighteen sedentary people with T2D (7 women/11 men, 52 ± 7 yr) completed 6 wk of RT. Before and after RT, overnight-fasted participants had blood sampled for clinical chemistries (glucose, insulin, lipids, HbA1c, and proinflammatory markers) and underwent an oral glucose challenge (OGC; 50 g glucose × 2 h) and a DEXA scan to assess body composition. Adipose tissue microvascular blood volume and flow were assessed at rest and 1 h post-OGC using contrast-enhanced ultrasound. RT significantly reduced fasting blood glucose ( P = 0.006), HbA1c ( P = 0.007), 2-h glucose area under the time curve post-OGC ( P = 0.014), and homeostatic model assessment of insulin resistance ( P = 0.005). This was accompanied by a small reduction in total body fat ( P = 0.002), trunk fat ( P = 0.023), and fasting triglyceride levels ( P = 0.029). Lean mass ( P = 0.003), circulating TNF-α ( P = 0.006), and soluble VCAM-1 ( P < 0.001) increased post-RT. There were no significant changes in adipose tissue microvascular blood volume or flow following RT; however those who did have a higher baseline microvascular blood flow post-RT also had lower fasting triglyceride levels ( r = -0.476, P = 0.045). The anthropometric, glycemic, and insulin-sensitizing benefits of 6 wk of RT in people with T2D are not associated with an improvement in adipose tissue microvascular responses; however, there may be an adipose tissue microvascular-linked benefit to fasting triglyceride levels.
Impact of breathing exercises in subjects with lung cancer undergoing surgical resection: A systematic review and meta-analysis.

AIMS AND OBJECTIVES To assess the effects of breathing exercises on postoperative pulmonary complications (PPCs), pulmonary function, 6-min walk distance (6MWD) and the length of hospital stay (LOS) in lung cancer patients undergoing lung surgery. BACKGROUND Lung cancer patients undergoing lung resection have poor pulmonary function and multiple PPCs. Breathing exercises may improve these symptoms. DESIGN Systematic literature review and meta-analysis were conducted. METHODS All entries to the following databases were searched up until 20 December 2017: PubMed, EMBASE Ovid, the Cochrane Central Register of Randomized Controlled Trials, Web of Science, Wanfang, Weipu and Chinese National Knowledge Infrastructure databases. Only randomised controlled trials (RCTs) were included in the analysis. RESULTS A total of sixteen articles including nine articles in Chinese language and seven articles in English met the inclusion criteria. Breathing exercises decreased PPCs, and in addition, the incidence of pneumonia and atelectasis in the postoperative subgroup was reduced. Predicted forced expiratory volume in 1 s (predicted FEV1 %), predicted forced vital capacity (predicted FVC%), FVC and FEV1 /FVC ratio had improved after breathing exercises, but the changes in FEV1 were not statistically significant. Furthermore, the LOS was significantly decreased, but no improvements were found in 6MWD. CONCLUSIONS The results showed that breathing exercises could improve lung function, decrease the incidence of PPCs and LOS in a sample of lung cancer patients undergoing pulmonary surgery. RELEVANCE TO CLINICAL PRACTICE The analysis suggests that breathing exercises should be considered as a respiratory rehabilitation programme for lung cancer patients undergoing lung surgery in clinical practice.
Imaging and serum biomarkers in connective tissue disease–associated interstitial lung diseases: correlation between lung ultrasound B-lines and KL-6 levels

B-Lines are a new sonographic hallmark of connective tissue disease–associated interstitial lung diseases (CTD-ILDs). Promising data have shown that B-lines are associated with high-resolution CT (HRCT), pulmonary function test and some clinical variables, expanding the armamentarium for screening of ILDs.1 Krebs von den Lungen-6 (KL-6) antigen is a mucin-like, high molecular weight glycoprotein expressed on the surface membrane of alveolar epithelial cells Ⅱ and bronchiolar epithelial cells, and increases following cellular injury and/or regeneration.2 Its role in patients with CTD-ILDs has been studied extensively, indicating KL-6 as a useful biomarker of lung fibrosis and severity of the disease.3 To the best of our knowledge, the correlation between B-lines and serum KL-6 levels in CTD-ILDs has not been reported until now. To investigate the relationship between these two markers, 60 Chinese patients with CTD-ILDs were enrolled. Patients with a history of asthma, chronic …
Accuracy and Reliability of Internet Resources Providing Information on Obstructive Sleep Apnea.

STUDY OBJECTIVES To evaluate the readability, content, and quality of internet information about obstructive sleep apnea (OSA). METHODS Three major search engines (Google, Yahoo, and Bing) were used to retrieve the first 200 hits for the term "sleep apnea. " The website contents were assessed using established guidelines, while the website quality was evaluated using the validated DISCERN instrument and Journal of the American Medical Association benchmarks. RESULTS In total, 243 websites met the inclusion criteria for this study. The websites were divided into five categories: scientific resource, foundation, news/ media report, commercial website, and personal commentary. The mean Flesch-Kincaid grade level, which indicated the readability of the websites, was 7.5. The quality of most websites was poor, with news/media reports and commercial websites exhibiting poorer quality than the others. The Health On the Net (HON) code, which certifies the reliability and credibility of online content regarding human health, was applied only to 14.3% websites; the reliability of all these websites was poor. The content score for the diagnosis and management of OSA was lower for news/media reports and commercial websites than for scientific resources. News/media reports exhibited the worst content scores. CONCLUSIONS Our findings suggest that most online health resources regarding OSA are not reliable and are inaccurate. Health care providers should be aware of the high variability in online information concerning OSA. COMMENTARY A commentary on this article appears in this issue on page 1643.
Burden of non‐motor symptoms in Parkinson's disease patients predicts improvement in quality of life during treatment with levodopa‐carbidopa intestinal gel

GLORIA, a registry conducted with 375 advanced Parkinson's disease patients treated with levodopa‐carbidopa intestinal gel (LCIG) for 24 months in routine clinical care, demonstrated significant reductions from baseline in ‘off’ time and ‘on’ time with dyskinesia and improvements in the Non‐Motor Symptom Scale (NMSS) total and individual domain scores, and in Parkinson's Disease Questionnaire 8 item (PDQ‐8) total score.
Unsupervised Scoliosis Diagnosis via a Joint Recognition Method with Multifeature Descriptors and Centroids Extraction

To solve the problem of scoliosis recognition without a labeled dataset, an unsupervised method is proposed by combining the cascade gentle AdaBoost (CGAdaBoost) classifier and distance regularized level set evolution (DRLSE). The main idea of the proposed method is to establish the relationship between individual vertebrae and the whole spine with vertebral centroids. Scoliosis recognition can be transferred into automatic vertebral detection and segmentation processes, which can avoid the manual data-labeling processing. In the CGAdaBoost classifier, diversified vertebrae images and multifeature descriptors are considered to generate more discriminative features, thus improving the vertebral detection accuracy. After that, the detected bounding box represents an appropriate initial contour of DRLSE to make the vertebral segmentation more accurate. It is helpful for the elimination of initialization sensitivity and quick convergence of vertebra boundaries. Meanwhile, vertebral centroids are extracted to connect the whole spine, thereby describing the spinal curvature. Different parts of the spine are determined as abnormal or normal in accordance with medical prior knowledge. The experimental results demonstrate that the proposed method cannot only effectively identify scoliosis with unlabeled spine CT images but also have superiority against other state-of-the-art methods.
Nerve Repair With Fibrin Nerve Conduit and Modified Suture Placement

Sutureless nerve repair has been regarded as a promising technique for nerve repair as the suture materials often results in neuroma formation and scar tissue that impede nerve regeneration. The aim of this study was to analyze the mechanical stability and morphological outcome of sutureless repair using fibrin glue conduit and an alternative approach of modified suture placement. Using rat sciatic nerve, we tested the following experimental conditions: conventional suture repair; single suture combined with fibrin glue repair, and fibrin conduit reinforced with modified suture or fibrin glue. Nerve detachment anatomical measures such as axon density, myelin, and fiber caliber were analyzed for evaluation of nerve regeneration. Muscle atrophy were evaluated by muscle wet weight and H&E staining. All animals in sutureless repair group exhibited complete detachment or elongation by two or four weeks after repair. No detachment was found in any other groups. Animals treated with fibrin conduit reinforced with modified suture showed better axonal regeneration with good alignment. There were no significant differences in axon caliber among the groups. Muscle atrophy was found in all groups and there was no significant difference in muscle wet‐weight among the groups. In summary, sutureless nerve repair with fibrin glue was mechanically unstable for resistance of mechanical stretches, fibrin glue conduit with modified suture placement is mechanically stable and resulted in better morphological outcome. Anat Rec, 301:1690–1696, 2018. © 2018 Wiley Periodicals, Inc.